data_2F18 # _entry.id 2F18 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 2F18 RCSB RCSB035326 WWPDB D_1000035326 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1HTY . unspecified PDB 1HWW . unspecified PDB 1HXK . unspecified PDB 1PS2 . unspecified PDB 1QWN . unspecified PDB 1QX1 . unspecified PDB 1R33 . unspecified PDB 1R34 . unspecified PDB 1TQS . unspecified PDB 1TQT . unspecified PDB 1TQU . unspecified PDB 1TQV . unspecified PDB 1TQW . unspecified PDB 2ALW . unspecified PDB 2F1A . unspecified PDB 2F1B . unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 2F18 _pdbx_database_status.recvd_initial_deposition_date 2005-11-14 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? _pdbx_database_status.pdb_format_compatible Y # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Kuntz, D.A.' 1 'Rose, D.R.' 2 # _citation.id primary _citation.title 'Evaluation of docking programs for predicting binding of Golgi alpha-mannosidase II inhibitors: a comparison with crystallography.' _citation.journal_abbrev Proteins _citation.journal_volume 69 _citation.page_first 160 _citation.page_last 176 _citation.year 2007 _citation.journal_id_ASTM PSFGEY _citation.country US _citation.journal_id_ISSN 0887-3585 _citation.journal_id_CSD 0867 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 17557336 _citation.pdbx_database_id_DOI 10.1002/prot.21479 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Englebienne, P.' 1 primary 'Fiaux, H.' 2 primary 'Kuntz, D.A.' 3 primary 'Corbeil, C.R.' 4 primary 'Gerber-Lemaire, S.' 5 primary 'Rose, D.R.' 6 primary 'Moitessier, N.' 7 # _cell.entry_id 2F18 _cell.length_a 68.965 _cell.length_b 109.724 _cell.length_c 138.911 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 2F18 _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 19 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Alpha-mannosidase II' 119701.617 1 3.2.1.114 ? 'CATALYTIC DOMAIN' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 3 non-polymer syn 'PHOSPHATE ION' 94.971 1 ? ? ? ? 4 non-polymer syn 'ZINC ION' 65.409 1 ? ? ? ? 5 non-polymer syn '(2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL' 252.309 1 ? ? ? ? 6 non-polymer syn '(4S)-2-METHYL-2,4-PENTANEDIOL' 118.174 1 ? ? ? ? 7 water nat water 18.015 1172 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN II, Golgi alpha-mannosidase II, AMAN II' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_seq_one_letter_code_can ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ARG n 1 2 SER n 1 3 SER n 1 4 HIS n 1 5 HIS n 1 6 HIS n 1 7 HIS n 1 8 HIS n 1 9 HIS n 1 10 GLY n 1 11 GLU n 1 12 PHE n 1 13 ASP n 1 14 ASP n 1 15 PRO n 1 16 ILE n 1 17 ARG n 1 18 PRO n 1 19 PRO n 1 20 LEU n 1 21 LYS n 1 22 VAL n 1 23 ALA n 1 24 ARG n 1 25 SER n 1 26 PRO n 1 27 ARG n 1 28 PRO n 1 29 GLY n 1 30 GLN n 1 31 CYS n 1 32 GLN n 1 33 ASP n 1 34 VAL n 1 35 VAL n 1 36 GLN n 1 37 ASP n 1 38 VAL n 1 39 PRO n 1 40 ASN n 1 41 VAL n 1 42 ASP n 1 43 VAL n 1 44 GLN n 1 45 MET n 1 46 LEU n 1 47 GLU n 1 48 LEU n 1 49 TYR n 1 50 ASP n 1 51 ARG n 1 52 MET n 1 53 SER n 1 54 PHE n 1 55 LYS n 1 56 ASP n 1 57 ILE n 1 58 ASP n 1 59 GLY n 1 60 GLY n 1 61 VAL n 1 62 TRP n 1 63 LYS n 1 64 GLN n 1 65 GLY n 1 66 TRP n 1 67 ASN n 1 68 ILE n 1 69 LYS n 1 70 TYR n 1 71 ASP n 1 72 PRO n 1 73 LEU n 1 74 LYS n 1 75 TYR n 1 76 ASN n 1 77 ALA n 1 78 HIS n 1 79 HIS n 1 80 LYS n 1 81 LEU n 1 82 LYS n 1 83 VAL n 1 84 PHE n 1 85 VAL n 1 86 VAL n 1 87 PRO n 1 88 HIS n 1 89 SER n 1 90 HIS n 1 91 ASN n 1 92 ASP n 1 93 PRO n 1 94 GLY n 1 95 TRP n 1 96 ILE n 1 97 GLN n 1 98 THR n 1 99 PHE n 1 100 GLU n 1 101 GLU n 1 102 TYR n 1 103 TYR n 1 104 GLN n 1 105 HIS n 1 106 ASP n 1 107 THR n 1 108 LYS n 1 109 HIS n 1 110 ILE n 1 111 LEU n 1 112 SER n 1 113 ASN n 1 114 ALA n 1 115 LEU n 1 116 ARG n 1 117 HIS n 1 118 LEU n 1 119 HIS n 1 120 ASP n 1 121 ASN n 1 122 PRO n 1 123 GLU n 1 124 MET n 1 125 LYS n 1 126 PHE n 1 127 ILE n 1 128 TRP n 1 129 ALA n 1 130 GLU n 1 131 ILE n 1 132 SER n 1 133 TYR n 1 134 PHE n 1 135 ALA n 1 136 ARG n 1 137 PHE n 1 138 TYR n 1 139 HIS n 1 140 ASP n 1 141 LEU n 1 142 GLY n 1 143 GLU n 1 144 ASN n 1 145 LYS n 1 146 LYS n 1 147 LEU n 1 148 GLN n 1 149 MET n 1 150 LYS n 1 151 SER n 1 152 ILE n 1 153 VAL n 1 154 LYS n 1 155 ASN n 1 156 GLY n 1 157 GLN n 1 158 LEU n 1 159 GLU n 1 160 PHE n 1 161 VAL n 1 162 THR n 1 163 GLY n 1 164 GLY n 1 165 TRP n 1 166 VAL n 1 167 MET n 1 168 PRO n 1 169 ASP n 1 170 GLU n 1 171 ALA n 1 172 ASN n 1 173 SER n 1 174 HIS n 1 175 TRP n 1 176 ARG n 1 177 ASN n 1 178 VAL n 1 179 LEU n 1 180 LEU n 1 181 GLN n 1 182 LEU n 1 183 THR n 1 184 GLU n 1 185 GLY n 1 186 GLN n 1 187 THR n 1 188 TRP n 1 189 LEU n 1 190 LYS n 1 191 GLN n 1 192 PHE n 1 193 MET n 1 194 ASN n 1 195 VAL n 1 196 THR n 1 197 PRO n 1 198 THR n 1 199 ALA n 1 200 SER n 1 201 TRP n 1 202 ALA n 1 203 ILE n 1 204 ASP n 1 205 PRO n 1 206 PHE n 1 207 GLY n 1 208 HIS n 1 209 SER n 1 210 PRO n 1 211 THR n 1 212 MET n 1 213 PRO n 1 214 TYR n 1 215 ILE n 1 216 LEU n 1 217 GLN n 1 218 LYS n 1 219 SER n 1 220 GLY n 1 221 PHE n 1 222 LYS n 1 223 ASN n 1 224 MET n 1 225 LEU n 1 226 ILE n 1 227 GLN n 1 228 ARG n 1 229 THR n 1 230 HIS n 1 231 TYR n 1 232 SER n 1 233 VAL n 1 234 LYS n 1 235 LYS n 1 236 GLU n 1 237 LEU n 1 238 ALA n 1 239 GLN n 1 240 GLN n 1 241 ARG n 1 242 GLN n 1 243 LEU n 1 244 GLU n 1 245 PHE n 1 246 LEU n 1 247 TRP n 1 248 ARG n 1 249 GLN n 1 250 ILE n 1 251 TRP n 1 252 ASP n 1 253 ASN n 1 254 LYS n 1 255 GLY n 1 256 ASP n 1 257 THR n 1 258 ALA n 1 259 LEU n 1 260 PHE n 1 261 THR n 1 262 HIS n 1 263 MET n 1 264 MET n 1 265 PRO n 1 266 PHE n 1 267 TYR n 1 268 SER n 1 269 TYR n 1 270 ASP n 1 271 ILE n 1 272 PRO n 1 273 HIS n 1 274 THR n 1 275 CYS n 1 276 GLY n 1 277 PRO n 1 278 ASP n 1 279 PRO n 1 280 LYS n 1 281 VAL n 1 282 CYS n 1 283 CYS n 1 284 GLN n 1 285 PHE n 1 286 ASP n 1 287 PHE n 1 288 LYS n 1 289 ARG n 1 290 MET n 1 291 GLY n 1 292 SER n 1 293 PHE n 1 294 GLY n 1 295 LEU n 1 296 SER n 1 297 CYS n 1 298 PRO n 1 299 TRP n 1 300 LYS n 1 301 VAL n 1 302 PRO n 1 303 PRO n 1 304 ARG n 1 305 THR n 1 306 ILE n 1 307 SER n 1 308 ASP n 1 309 GLN n 1 310 ASN n 1 311 VAL n 1 312 ALA n 1 313 ALA n 1 314 ARG n 1 315 SER n 1 316 ASP n 1 317 LEU n 1 318 LEU n 1 319 VAL n 1 320 ASP n 1 321 GLN n 1 322 TRP n 1 323 LYS n 1 324 LYS n 1 325 LYS n 1 326 ALA n 1 327 GLU n 1 328 LEU n 1 329 TYR n 1 330 ARG n 1 331 THR n 1 332 ASN n 1 333 VAL n 1 334 LEU n 1 335 LEU n 1 336 ILE n 1 337 PRO n 1 338 LEU n 1 339 GLY n 1 340 ASP n 1 341 ASP n 1 342 PHE n 1 343 ARG n 1 344 PHE n 1 345 LYS n 1 346 GLN n 1 347 ASN n 1 348 THR n 1 349 GLU n 1 350 TRP n 1 351 ASP n 1 352 VAL n 1 353 GLN n 1 354 ARG n 1 355 VAL n 1 356 ASN n 1 357 TYR n 1 358 GLU n 1 359 ARG n 1 360 LEU n 1 361 PHE n 1 362 GLU n 1 363 HIS n 1 364 ILE n 1 365 ASN n 1 366 SER n 1 367 GLN n 1 368 ALA n 1 369 HIS n 1 370 PHE n 1 371 ASN n 1 372 VAL n 1 373 GLN n 1 374 ALA n 1 375 GLN n 1 376 PHE n 1 377 GLY n 1 378 THR n 1 379 LEU n 1 380 GLN n 1 381 GLU n 1 382 TYR n 1 383 PHE n 1 384 ASP n 1 385 ALA n 1 386 VAL n 1 387 HIS n 1 388 GLN n 1 389 ALA n 1 390 GLU n 1 391 ARG n 1 392 ALA n 1 393 GLY n 1 394 GLN n 1 395 ALA n 1 396 GLU n 1 397 PHE n 1 398 PRO n 1 399 THR n 1 400 LEU n 1 401 SER n 1 402 GLY n 1 403 ASP n 1 404 PHE n 1 405 PHE n 1 406 THR n 1 407 TYR n 1 408 ALA n 1 409 ASP n 1 410 ARG n 1 411 SER n 1 412 ASP n 1 413 ASN n 1 414 TYR n 1 415 TRP n 1 416 SER n 1 417 GLY n 1 418 TYR n 1 419 TYR n 1 420 THR n 1 421 SER n 1 422 ARG n 1 423 PRO n 1 424 TYR n 1 425 HIS n 1 426 LYS n 1 427 ARG n 1 428 MET n 1 429 ASP n 1 430 ARG n 1 431 VAL n 1 432 LEU n 1 433 MET n 1 434 HIS n 1 435 TYR n 1 436 VAL n 1 437 ARG n 1 438 ALA n 1 439 ALA n 1 440 GLU n 1 441 MET n 1 442 LEU n 1 443 SER n 1 444 ALA n 1 445 TRP n 1 446 HIS n 1 447 SER n 1 448 TRP n 1 449 ASP n 1 450 GLY n 1 451 MET n 1 452 ALA n 1 453 ARG n 1 454 ILE n 1 455 GLU n 1 456 GLU n 1 457 ARG n 1 458 LEU n 1 459 GLU n 1 460 GLN n 1 461 ALA n 1 462 ARG n 1 463 ARG n 1 464 GLU n 1 465 LEU n 1 466 SER n 1 467 LEU n 1 468 PHE n 1 469 GLN n 1 470 HIS n 1 471 HIS n 1 472 ASP n 1 473 GLY n 1 474 ILE n 1 475 THR n 1 476 GLY n 1 477 THR n 1 478 ALA n 1 479 LYS n 1 480 THR n 1 481 HIS n 1 482 VAL n 1 483 VAL n 1 484 VAL n 1 485 ASP n 1 486 TYR n 1 487 GLU n 1 488 GLN n 1 489 ARG n 1 490 MET n 1 491 GLN n 1 492 GLU n 1 493 ALA n 1 494 LEU n 1 495 LYS n 1 496 ALA n 1 497 CYS n 1 498 GLN n 1 499 MET n 1 500 VAL n 1 501 MET n 1 502 GLN n 1 503 GLN n 1 504 SER n 1 505 VAL n 1 506 TYR n 1 507 ARG n 1 508 LEU n 1 509 LEU n 1 510 THR n 1 511 LYS n 1 512 PRO n 1 513 SER n 1 514 ILE n 1 515 TYR n 1 516 SER n 1 517 PRO n 1 518 ASP n 1 519 PHE n 1 520 SER n 1 521 PHE n 1 522 SER n 1 523 TYR n 1 524 PHE n 1 525 THR n 1 526 LEU n 1 527 ASP n 1 528 ASP n 1 529 SER n 1 530 ARG n 1 531 TRP n 1 532 PRO n 1 533 GLY n 1 534 SER n 1 535 GLY n 1 536 VAL n 1 537 GLU n 1 538 ASP n 1 539 SER n 1 540 ARG n 1 541 THR n 1 542 THR n 1 543 ILE n 1 544 ILE n 1 545 LEU n 1 546 GLY n 1 547 GLU n 1 548 ASP n 1 549 ILE n 1 550 LEU n 1 551 PRO n 1 552 SER n 1 553 LYS n 1 554 HIS n 1 555 VAL n 1 556 VAL n 1 557 MET n 1 558 HIS n 1 559 ASN n 1 560 THR n 1 561 LEU n 1 562 PRO n 1 563 HIS n 1 564 TRP n 1 565 ARG n 1 566 GLU n 1 567 GLN n 1 568 LEU n 1 569 VAL n 1 570 ASP n 1 571 PHE n 1 572 TYR n 1 573 VAL n 1 574 SER n 1 575 SER n 1 576 PRO n 1 577 PHE n 1 578 VAL n 1 579 SER n 1 580 VAL n 1 581 THR n 1 582 ASP n 1 583 LEU n 1 584 ALA n 1 585 ASN n 1 586 ASN n 1 587 PRO n 1 588 VAL n 1 589 GLU n 1 590 ALA n 1 591 GLN n 1 592 VAL n 1 593 SER n 1 594 PRO n 1 595 VAL n 1 596 TRP n 1 597 SER n 1 598 TRP n 1 599 HIS n 1 600 HIS n 1 601 ASP n 1 602 THR n 1 603 LEU n 1 604 THR n 1 605 LYS n 1 606 THR n 1 607 ILE n 1 608 HIS n 1 609 PRO n 1 610 GLN n 1 611 GLY n 1 612 SER n 1 613 THR n 1 614 THR n 1 615 LYS n 1 616 TYR n 1 617 ARG n 1 618 ILE n 1 619 ILE n 1 620 PHE n 1 621 LYS n 1 622 ALA n 1 623 ARG n 1 624 VAL n 1 625 PRO n 1 626 PRO n 1 627 MET n 1 628 GLY n 1 629 LEU n 1 630 ALA n 1 631 THR n 1 632 TYR n 1 633 VAL n 1 634 LEU n 1 635 THR n 1 636 ILE n 1 637 SER n 1 638 ASP n 1 639 SER n 1 640 LYS n 1 641 PRO n 1 642 GLU n 1 643 HIS n 1 644 THR n 1 645 SER n 1 646 TYR n 1 647 ALA n 1 648 SER n 1 649 ASN n 1 650 LEU n 1 651 LEU n 1 652 LEU n 1 653 ARG n 1 654 LYS n 1 655 ASN n 1 656 PRO n 1 657 THR n 1 658 SER n 1 659 LEU n 1 660 PRO n 1 661 LEU n 1 662 GLY n 1 663 GLN n 1 664 TYR n 1 665 PRO n 1 666 GLU n 1 667 ASP n 1 668 VAL n 1 669 LYS n 1 670 PHE n 1 671 GLY n 1 672 ASP n 1 673 PRO n 1 674 ARG n 1 675 GLU n 1 676 ILE n 1 677 SER n 1 678 LEU n 1 679 ARG n 1 680 VAL n 1 681 GLY n 1 682 ASN n 1 683 GLY n 1 684 PRO n 1 685 THR n 1 686 LEU n 1 687 ALA n 1 688 PHE n 1 689 SER n 1 690 GLU n 1 691 GLN n 1 692 GLY n 1 693 LEU n 1 694 LEU n 1 695 LYS n 1 696 SER n 1 697 ILE n 1 698 GLN n 1 699 LEU n 1 700 THR n 1 701 GLN n 1 702 ASP n 1 703 SER n 1 704 PRO n 1 705 HIS n 1 706 VAL n 1 707 PRO n 1 708 VAL n 1 709 HIS n 1 710 PHE n 1 711 LYS n 1 712 PHE n 1 713 LEU n 1 714 LYS n 1 715 TYR n 1 716 GLY n 1 717 VAL n 1 718 ARG n 1 719 SER n 1 720 HIS n 1 721 GLY n 1 722 ASP n 1 723 ARG n 1 724 SER n 1 725 GLY n 1 726 ALA n 1 727 TYR n 1 728 LEU n 1 729 PHE n 1 730 LEU n 1 731 PRO n 1 732 ASN n 1 733 GLY n 1 734 PRO n 1 735 ALA n 1 736 SER n 1 737 PRO n 1 738 VAL n 1 739 GLU n 1 740 LEU n 1 741 GLY n 1 742 GLN n 1 743 PRO n 1 744 VAL n 1 745 VAL n 1 746 LEU n 1 747 VAL n 1 748 THR n 1 749 LYS n 1 750 GLY n 1 751 LYS n 1 752 LEU n 1 753 GLU n 1 754 SER n 1 755 SER n 1 756 VAL n 1 757 SER n 1 758 VAL n 1 759 GLY n 1 760 LEU n 1 761 PRO n 1 762 SER n 1 763 VAL n 1 764 VAL n 1 765 HIS n 1 766 GLN n 1 767 THR n 1 768 ILE n 1 769 MET n 1 770 ARG n 1 771 GLY n 1 772 GLY n 1 773 ALA n 1 774 PRO n 1 775 GLU n 1 776 ILE n 1 777 ARG n 1 778 ASN n 1 779 LEU n 1 780 VAL n 1 781 ASP n 1 782 ILE n 1 783 GLY n 1 784 SER n 1 785 LEU n 1 786 ASP n 1 787 ASN n 1 788 THR n 1 789 GLU n 1 790 ILE n 1 791 VAL n 1 792 MET n 1 793 ARG n 1 794 LEU n 1 795 GLU n 1 796 THR n 1 797 HIS n 1 798 ILE n 1 799 ASP n 1 800 SER n 1 801 GLY n 1 802 ASP n 1 803 ILE n 1 804 PHE n 1 805 TYR n 1 806 THR n 1 807 ASP n 1 808 LEU n 1 809 ASN n 1 810 GLY n 1 811 LEU n 1 812 GLN n 1 813 PHE n 1 814 ILE n 1 815 LYS n 1 816 ARG n 1 817 ARG n 1 818 ARG n 1 819 LEU n 1 820 ASP n 1 821 LYS n 1 822 LEU n 1 823 PRO n 1 824 LEU n 1 825 GLN n 1 826 ALA n 1 827 ASN n 1 828 TYR n 1 829 TYR n 1 830 PRO n 1 831 ILE n 1 832 PRO n 1 833 SER n 1 834 GLY n 1 835 MET n 1 836 PHE n 1 837 ILE n 1 838 GLU n 1 839 ASP n 1 840 ALA n 1 841 ASN n 1 842 THR n 1 843 ARG n 1 844 LEU n 1 845 THR n 1 846 LEU n 1 847 LEU n 1 848 THR n 1 849 GLY n 1 850 GLN n 1 851 PRO n 1 852 LEU n 1 853 GLY n 1 854 GLY n 1 855 SER n 1 856 SER n 1 857 LEU n 1 858 ALA n 1 859 SER n 1 860 GLY n 1 861 GLU n 1 862 LEU n 1 863 GLU n 1 864 ILE n 1 865 MET n 1 866 GLN n 1 867 ASP n 1 868 ARG n 1 869 ARG n 1 870 LEU n 1 871 ALA n 1 872 SER n 1 873 ASP n 1 874 ASP n 1 875 GLU n 1 876 ARG n 1 877 GLY n 1 878 LEU n 1 879 GLY n 1 880 GLN n 1 881 GLY n 1 882 VAL n 1 883 LEU n 1 884 ASP n 1 885 ASN n 1 886 LYS n 1 887 PRO n 1 888 VAL n 1 889 LEU n 1 890 HIS n 1 891 ILE n 1 892 TYR n 1 893 ARG n 1 894 LEU n 1 895 VAL n 1 896 LEU n 1 897 GLU n 1 898 LYS n 1 899 VAL n 1 900 ASN n 1 901 ASN n 1 902 CYS n 1 903 VAL n 1 904 ARG n 1 905 PRO n 1 906 SER n 1 907 LYS n 1 908 LEU n 1 909 HIS n 1 910 PRO n 1 911 ALA n 1 912 GLY n 1 913 TYR n 1 914 LEU n 1 915 THR n 1 916 SER n 1 917 ALA n 1 918 ALA n 1 919 HIS n 1 920 LYS n 1 921 ALA n 1 922 SER n 1 923 GLN n 1 924 SER n 1 925 LEU n 1 926 LEU n 1 927 ASP n 1 928 PRO n 1 929 LEU n 1 930 ASP n 1 931 LYS n 1 932 PHE n 1 933 ILE n 1 934 PHE n 1 935 ALA n 1 936 GLU n 1 937 ASN n 1 938 GLU n 1 939 TRP n 1 940 ILE n 1 941 GLY n 1 942 ALA n 1 943 GLN n 1 944 GLY n 1 945 GLN n 1 946 PHE n 1 947 GLY n 1 948 GLY n 1 949 ASP n 1 950 HIS n 1 951 PRO n 1 952 SER n 1 953 ALA n 1 954 ARG n 1 955 GLU n 1 956 ASP n 1 957 LEU n 1 958 ASP n 1 959 VAL n 1 960 SER n 1 961 VAL n 1 962 MET n 1 963 ARG n 1 964 ARG n 1 965 LEU n 1 966 THR n 1 967 LYS n 1 968 SER n 1 969 SER n 1 970 ALA n 1 971 LYS n 1 972 THR n 1 973 GLN n 1 974 ARG n 1 975 VAL n 1 976 GLY n 1 977 TYR n 1 978 VAL n 1 979 LEU n 1 980 HIS n 1 981 ARG n 1 982 THR n 1 983 ASN n 1 984 LEU n 1 985 MET n 1 986 GLN n 1 987 CYS n 1 988 GLY n 1 989 THR n 1 990 PRO n 1 991 GLU n 1 992 GLU n 1 993 HIS n 1 994 THR n 1 995 GLN n 1 996 LYS n 1 997 LEU n 1 998 ASP n 1 999 VAL n 1 1000 CYS n 1 1001 HIS n 1 1002 LEU n 1 1003 LEU n 1 1004 PRO n 1 1005 ASN n 1 1006 VAL n 1 1007 ALA n 1 1008 ARG n 1 1009 CYS n 1 1010 GLU n 1 1011 ARG n 1 1012 THR n 1 1013 THR n 1 1014 LEU n 1 1015 THR n 1 1016 PHE n 1 1017 LEU n 1 1018 GLN n 1 1019 ASN n 1 1020 LEU n 1 1021 GLU n 1 1022 HIS n 1 1023 LEU n 1 1024 ASP n 1 1025 GLY n 1 1026 MET n 1 1027 VAL n 1 1028 ALA n 1 1029 PRO n 1 1030 GLU n 1 1031 VAL n 1 1032 CYS n 1 1033 PRO n 1 1034 MET n 1 1035 GLU n 1 1036 THR n 1 1037 ALA n 1 1038 ALA n 1 1039 TYR n 1 1040 VAL n 1 1041 SER n 1 1042 SER n 1 1043 HIS n 1 1044 SER n 1 1045 SER n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name 'fruit fly' _entity_src_gen.gene_src_genus Drosophila _entity_src_gen.pdbx_gene_src_gene 'alpha-Man-II, GmII' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 7227 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'fruit fly' _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7227 _entity_src_gen.host_org_genus Drosophila _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain 'S2 cell' _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type 'Stable transfection plasmid' _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pMTBIP_NHIS _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name GB _struct_ref.db_code CAA54732 _struct_ref.pdbx_db_accession 517481 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;DDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHND PGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEAN SHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWD NKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTN VLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTLSGDFFTYADRSD NYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQE ALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFY VSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLL RKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSHGDRSGAYLFLPN GPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQ FIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVLHIY RLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVSVMRRLTKSSAKT QRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYVSSHSS ; _struct_ref.pdbx_align_begin 76 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 2F18 _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 13 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 1045 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession 517481 _struct_ref_seq.db_align_beg 76 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 1108 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 13 _struct_ref_seq.pdbx_auth_seq_align_end 1045 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 2F18 ARG A 1 ? GB 517481 ? ? 'EXPRESSION TAG' 1 1 1 2F18 SER A 2 ? GB 517481 ? ? 'EXPRESSION TAG' 2 2 1 2F18 SER A 3 ? GB 517481 ? ? 'EXPRESSION TAG' 3 3 1 2F18 HIS A 4 ? GB 517481 ? ? 'EXPRESSION TAG' 4 4 1 2F18 HIS A 5 ? GB 517481 ? ? 'EXPRESSION TAG' 5 5 1 2F18 HIS A 6 ? GB 517481 ? ? 'EXPRESSION TAG' 6 6 1 2F18 HIS A 7 ? GB 517481 ? ? 'EXPRESSION TAG' 7 7 1 2F18 HIS A 8 ? GB 517481 ? ? 'EXPRESSION TAG' 8 8 1 2F18 HIS A 9 ? GB 517481 ? ? 'EXPRESSION TAG' 9 9 1 2F18 GLY A 10 ? GB 517481 ? ? 'EXPRESSION TAG' 10 10 1 2F18 GLU A 11 ? GB 517481 ? ? 'EXPRESSION TAG' 11 11 1 2F18 PHE A 12 ? GB 517481 ? ? 'EXPRESSION TAG' 12 12 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GB1 non-polymer . '(2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL' ? 'C13 H20 N2 O3' 252.309 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MPD non-polymer . '(4S)-2-METHYL-2,4-PENTANEDIOL' ? 'C6 H14 O2' 118.174 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PO4 non-polymer . 'PHOSPHATE ION' ? 'O4 P -3' 94.971 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.entry_id 2F18 _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.19 _exptl_crystal.density_percent_sol 43.94 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 298 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 7 _exptl_crystal_grow.pdbx_details 'Tris, PEG 6K, MPD, NaCl, pH 7, VAPOR DIFFUSION, HANGING DROP, temperature 298K' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100.0 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 4' _diffrn_detector.pdbx_collection_date 2004-12-10 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9793376 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'APS BEAMLINE 19-ID' _diffrn_source.pdbx_synchrotron_site APS _diffrn_source.pdbx_synchrotron_beamline 19-ID _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.9793376 # _reflns.entry_id 2F18 _reflns.observed_criterion_sigma_I 2 _reflns.observed_criterion_sigma_F 2 _reflns.d_resolution_low 30 _reflns.d_resolution_high 1.3 _reflns.number_obs 257516 _reflns.number_all 257854 _reflns.percent_possible_obs 99.9 _reflns.pdbx_Rmerge_I_obs 0.066 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 39 _reflns.B_iso_Wilson_estimate 13.0 _reflns.pdbx_redundancy 10.8 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 1.3 _reflns_shell.d_res_low 1.35 _reflns_shell.percent_possible_all 99.6 _reflns_shell.Rmerge_I_obs 0.35 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 5.1 _reflns_shell.pdbx_redundancy 5 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 25391 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 2F18 _refine.ls_number_reflns_obs 252466 _refine.ls_number_reflns_all 258145 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF 536245.31 _refine.pdbx_data_cutoff_low_absF 0.000000 _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 29.85 _refine.ls_d_res_high 1.30 _refine.ls_percent_reflns_obs 97.8 _refine.ls_R_factor_obs 0.168 _refine.ls_R_factor_all 0.168 _refine.ls_R_factor_R_work 0.168 _refine.ls_R_factor_R_free 0.18 _refine.ls_R_factor_R_free_error 0.003 _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 1.9 _refine.ls_number_reflns_R_free 4740 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean 15.8 _refine.aniso_B[1][1] -0.81 _refine.aniso_B[2][2] 0.89 _refine.aniso_B[3][3] -0.08 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details 'FLAT MODEL' _refine.solvent_model_param_ksol 0.325707 _refine.solvent_model_param_bsol 43.9992 _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details ;The data was collected to 1.21, but since the I/sigmaI was not great in the last shell, data was only refined to a 1.3 A stucture. However sf file contains all the data. The difference in unique reflections is a difference in the way good reflections are assessed between scalepack and CNS. ; _refine.pdbx_starting_model 'PDB ENTRY 1HWW' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model RESTRAINED _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_overall_phase_error ? _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 2F18 _refine_analyze.Luzzati_coordinate_error_obs 0.13 _refine_analyze.Luzzati_sigma_a_obs 0.10 _refine_analyze.Luzzati_d_res_low_obs 30.00 _refine_analyze.Luzzati_coordinate_error_free 0.14 _refine_analyze.Luzzati_sigma_a_free 0.10 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 8181 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 46 _refine_hist.number_atoms_solvent 1172 _refine_hist.number_atoms_total 9399 _refine_hist.d_res_high 1.30 _refine_hist.d_res_low 29.85 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d 0.019 ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg 1.9 ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d 25.4 ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d 1.31 ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_mcbond_it 0.97 1.50 ? ? 'X-RAY DIFFRACTION' ? c_mcangle_it 1.59 2.00 ? ? 'X-RAY DIFFRACTION' ? c_scbond_it 1.88 2.00 ? ? 'X-RAY DIFFRACTION' ? c_scangle_it 2.92 2.50 ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used 6 _refine_ls_shell.d_res_high 1.30 _refine_ls_shell.d_res_low 1.38 _refine_ls_shell.number_reflns_R_work 38928 _refine_ls_shell.R_factor_R_work 0.226 _refine_ls_shell.percent_reflns_obs 93.6 _refine_ls_shell.R_factor_R_free 0.231 _refine_ls_shell.R_factor_R_free_error 0.008 _refine_ls_shell.percent_reflns_R_free 2.4 _refine_ls_shell.number_reflns_R_free 945 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # loop_ _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file _pdbx_xplor_file.pdbx_refine_id 1 protein_rep.param protein_rep.top 'X-RAY DIFFRACTION' 2 carbohydrate.param carbohydrate.top 'X-RAY DIFFRACTION' 3 cis_peptide.param cis_peptide.top 'X-RAY DIFFRACTION' 4 water_rep.param water_rep.top 'X-RAY DIFFRACTION' 5 ion.param ion.top 'X-RAY DIFFRACTION' 6 po4.par po4.top 'X-RAY DIFFRACTION' 7 GB1.par GB1.top 'X-RAY DIFFRACTION' # _struct.entry_id 2F18 _struct.title 'GOLGI ALPHA-MANNOSIDASE II complex with (2R,3R,4S)-2-({[(1R)-2-hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diol' _struct.pdbx_descriptor 'Alpha-mannosidase II (E.C.3.2.1.114)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 2F18 _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'GLYCOSYL HYDROLASE FAMILY 38, Hydrolase' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 6 ? G N N 7 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 MET A 45 ? MET A 52 ? MET A 45 MET A 52 1 ? 8 HELX_P HELX_P2 2 ASP A 71 ? TYR A 75 ? ASP A 71 TYR A 75 5 ? 5 HELX_P HELX_P3 3 THR A 98 ? ASP A 106 ? THR A 98 ASP A 106 1 ? 9 HELX_P HELX_P4 4 ASP A 106 ? ASN A 121 ? ASP A 106 ASN A 121 1 ? 16 HELX_P HELX_P5 5 GLU A 130 ? HIS A 139 ? GLU A 130 HIS A 139 1 ? 10 HELX_P HELX_P6 6 GLY A 142 ? ASN A 155 ? GLY A 142 ASN A 155 1 ? 14 HELX_P HELX_P7 7 HIS A 174 ? ASN A 194 ? HIS A 174 ASN A 194 1 ? 21 HELX_P HELX_P8 8 PRO A 210 ? LYS A 218 ? PRO A 210 LYS A 218 1 ? 9 HELX_P HELX_P9 9 HIS A 230 ? GLN A 240 ? HIS A 230 GLN A 240 1 ? 11 HELX_P HELX_P10 10 ASP A 270 ? THR A 274 ? ASP A 270 THR A 274 5 ? 5 HELX_P HELX_P11 11 ASP A 278 ? CYS A 283 ? ASP A 278 CYS A 283 1 ? 6 HELX_P HELX_P12 12 GLN A 284 ? MET A 290 ? GLN A 284 MET A 290 5 ? 7 HELX_P HELX_P13 13 ASN A 310 ? GLU A 327 ? ASN A 310 GLU A 327 1 ? 18 HELX_P HELX_P14 14 GLN A 346 ? GLN A 367 ? GLN A 346 GLN A 367 1 ? 22 HELX_P HELX_P15 15 ALA A 368 ? PHE A 370 ? ALA A 368 PHE A 370 5 ? 3 HELX_P HELX_P16 16 THR A 378 ? ALA A 392 ? THR A 378 ALA A 392 1 ? 15 HELX_P HELX_P17 17 SER A 416 ? THR A 420 ? SER A 416 THR A 420 5 ? 5 HELX_P HELX_P18 18 ARG A 422 ? TRP A 445 ? ARG A 422 TRP A 445 1 ? 24 HELX_P HELX_P19 19 ASP A 449 ? ALA A 452 ? ASP A 449 ALA A 452 5 ? 4 HELX_P HELX_P20 20 ARG A 453 ? GLN A 469 ? ARG A 453 GLN A 469 1 ? 17 HELX_P HELX_P21 21 LYS A 479 ? LEU A 509 ? LYS A 479 LEU A 509 1 ? 31 HELX_P HELX_P22 22 PRO A 823 ? TYR A 828 ? PRO A 823 TYR A 828 5 ? 6 HELX_P HELX_P23 23 THR A 915 ? ASP A 927 ? THR A 915 ASP A 927 1 ? 13 HELX_P HELX_P24 24 ASP A 998 ? LEU A 1002 ? ASP A 998 LEU A 1002 5 ? 5 HELX_P HELX_P25 25 ASP A 1024 ? VAL A 1027 ? ASP A 1024 VAL A 1027 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 31 SG ? ? ? 1_555 A CYS 1032 SG ? ? A CYS 31 A CYS 1032 1_555 ? ? ? ? ? ? ? 2.062 ? disulf2 disulf ? ? A CYS 275 SG ? ? ? 1_555 A CYS 282 SG ? ? A CYS 275 A CYS 282 1_555 ? ? ? ? ? ? ? 2.032 ? disulf3 disulf ? ? A CYS 283 SG ? ? ? 1_555 A CYS 297 SG ? ? A CYS 283 A CYS 297 1_555 ? ? ? ? ? ? ? 2.058 ? disulf4 disulf ? ? A CYS 902 SG ? ? ? 1_555 A CYS 987 SG ? ? A CYS 902 A CYS 987 1_555 ? ? ? ? ? ? ? 2.056 ? disulf5 disulf ? ? A CYS 1000 SG ? ? ? 1_555 A CYS 1009 SG ? ? A CYS 1000 A CYS 1009 1_555 ? ? ? ? ? ? ? 2.000 ? covale1 covale ? ? A ASN 194 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 194 A NAG 1802 1_555 ? ? ? ? ? ? ? 1.459 ? metalc1 metalc ? ? A HIS 90 NE2 ? ? ? 1_555 D ZN . ZN ? ? A HIS 90 A ZN 1805 1_555 ? ? ? ? ? ? ? 2.116 ? metalc2 metalc ? ? A ASP 92 OD1 ? ? ? 1_555 D ZN . ZN ? ? A ASP 92 A ZN 1805 1_555 ? ? ? ? ? ? ? 2.129 ? metalc3 metalc ? ? A ASP 204 OD2 ? ? ? 1_555 D ZN . ZN ? ? A ASP 204 A ZN 1805 1_555 ? ? ? ? ? ? ? 2.086 ? metalc4 metalc ? ? A HIS 471 NE2 ? ? ? 1_555 D ZN . ZN ? ? A HIS 471 A ZN 1805 1_555 ? ? ? ? ? ? ? 2.112 ? metalc5 metalc ? ? D ZN . ZN ? ? ? 1_555 E GB1 . O3 ? ? A ZN 1805 A GB1 1804 1_555 ? ? ? ? ? ? ? 2.178 ? metalc6 metalc ? ? D ZN . ZN ? ? ? 1_555 E GB1 . O4 ? ? A ZN 1805 A GB1 1804 1_555 ? ? ? ? ? ? ? 2.261 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PHE 405 A . ? PHE 405 A THR 406 A ? THR 406 A 1 -4.30 2 TRP 531 A . ? TRP 531 A PRO 532 A ? PRO 532 A 1 -0.18 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 6 ? B ? 3 ? C ? 2 ? D ? 6 ? E ? 5 ? F ? 5 ? G ? 12 ? H ? 5 ? I ? 8 ? J ? 5 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? anti-parallel A 4 5 ? parallel A 5 6 ? parallel B 1 2 ? parallel B 2 3 ? parallel C 1 2 ? parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel D 4 5 ? anti-parallel D 5 6 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel E 4 5 ? anti-parallel F 1 2 ? parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel F 4 5 ? parallel G 1 2 ? parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel G 4 5 ? anti-parallel G 5 6 ? anti-parallel G 6 7 ? anti-parallel G 7 8 ? anti-parallel G 8 9 ? anti-parallel G 9 10 ? anti-parallel G 10 11 ? anti-parallel G 11 12 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel I 4 5 ? anti-parallel I 5 6 ? anti-parallel I 6 7 ? anti-parallel I 7 8 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 VAL A 43 ? GLN A 44 ? VAL A 43 GLN A 44 A 2 THR A 399 ? SER A 401 ? THR A 399 SER A 401 A 3 GLU A 244 ? TRP A 247 ? GLU A 244 TRP A 247 A 4 LEU A 259 ? MET A 263 ? LEU A 259 MET A 263 A 5 ASN A 223 ? ILE A 226 ? ASN A 223 ILE A 226 A 6 ALA A 199 ? ALA A 202 ? ALA A 199 ALA A 202 B 1 VAL A 333 ? ASP A 341 ? VAL A 333 ASP A 341 B 2 LEU A 81 ? HIS A 90 ? LEU A 81 HIS A 90 B 3 VAL A 372 ? PHE A 376 ? VAL A 372 PHE A 376 C 1 PHE A 126 ? TRP A 128 ? PHE A 126 TRP A 128 C 2 LEU A 158 ? PHE A 160 ? LEU A 158 PHE A 160 D 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 D 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 D 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 D 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 D 5 VAL A 578 ? ASP A 582 ? VAL A 578 ASP A 582 D 6 PRO A 587 ? VAL A 588 ? PRO A 587 VAL A 588 E 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 E 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 E 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 E 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 E 5 GLN A 945 ? PHE A 946 ? GLN A 945 PHE A 946 F 1 THR A 542 ? ILE A 543 ? THR A 542 ILE A 543 F 2 ARG A 565 ? VAL A 573 ? ARG A 565 VAL A 573 F 3 THR A 606 ? VAL A 624 ? THR A 606 VAL A 624 F 4 ALA A 590 ? ASP A 601 ? ALA A 590 ASP A 601 F 5 THR A 644 ? TYR A 646 ? THR A 644 TYR A 646 G 1 LYS A 669 ? GLY A 671 ? LYS A 669 GLY A 671 G 2 SER A 648 ? LEU A 652 ? SER A 648 LEU A 652 G 3 VAL A 745 ? LYS A 749 ? VAL A 745 LYS A 749 G 4 SER A 754 ? LEU A 760 ? SER A 754 LEU A 760 G 5 VAL A 763 ? MET A 769 ? VAL A 763 MET A 769 G 6 GLU A 775 ? VAL A 780 ? GLU A 775 VAL A 780 G 7 VAL A 888 ? LYS A 898 ? VAL A 888 LYS A 898 G 8 THR A 842 ? THR A 848 ? THR A 842 THR A 848 G 9 GLY A 834 ? GLU A 838 ? GLY A 834 GLU A 838 G 10 ILE A 803 ? LEU A 808 ? ILE A 803 LEU A 808 G 11 GLN A 812 ? ARG A 817 ? GLN A 812 ARG A 817 G 12 ALA A 911 ? GLY A 912 ? ALA A 911 GLY A 912 H 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 H 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 H 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 H 4 HIS A 705 ? TYR A 715 ? HIS A 705 TYR A 715 H 5 SER A 736 ? PRO A 737 ? SER A 736 PRO A 737 I 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 I 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 I 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 I 4 HIS A 705 ? TYR A 715 ? HIS A 705 TYR A 715 I 5 THR A 788 ? THR A 796 ? THR A 788 THR A 796 I 6 GLU A 861 ? ARG A 869 ? GLU A 861 ARG A 869 I 7 LEU A 852 ? SER A 855 ? LEU A 852 SER A 855 I 8 TYR A 829 ? ILE A 831 ? TYR A 829 ILE A 831 J 1 LEU A 957 ? ARG A 964 ? LEU A 957 ARG A 964 J 2 GLN A 973 ? ARG A 981 ? GLN A 973 ARG A 981 J 3 THR A 1036 ? HIS A 1043 ? THR A 1036 HIS A 1043 J 4 VAL A 1006 ? THR A 1012 ? VAL A 1006 THR A 1012 J 5 ASN A 1019 ? HIS A 1022 ? ASN A 1019 HIS A 1022 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N VAL A 43 ? N VAL A 43 O SER A 401 ? O SER A 401 A 2 3 O LEU A 400 ? O LEU A 400 N LEU A 246 ? N LEU A 246 A 3 4 N PHE A 245 ? N PHE A 245 O THR A 261 ? O THR A 261 A 4 5 O HIS A 262 ? O HIS A 262 N MET A 224 ? N MET A 224 A 5 6 O LEU A 225 ? O LEU A 225 N ALA A 202 ? N ALA A 202 B 1 2 O LEU A 334 ? O LEU A 334 N LYS A 82 ? N LYS A 82 B 2 3 N VAL A 85 ? N VAL A 85 O GLN A 375 ? O GLN A 375 C 1 2 N PHE A 126 ? N PHE A 126 O GLU A 159 ? O GLU A 159 D 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 D 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 D 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 D 4 5 O VAL A 633 ? O VAL A 633 N THR A 581 ? N THR A 581 D 5 6 N VAL A 580 ? N VAL A 580 O VAL A 588 ? O VAL A 588 E 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 E 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 E 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 E 4 5 N LEU A 629 ? N LEU A 629 O PHE A 946 ? O PHE A 946 F 1 2 N ILE A 543 ? N ILE A 543 O TYR A 572 ? O TYR A 572 F 2 3 N ARG A 565 ? N ARG A 565 O VAL A 624 ? O VAL A 624 F 3 4 O GLN A 610 ? O GLN A 610 N SER A 597 ? N SER A 597 F 4 5 N VAL A 592 ? N VAL A 592 O SER A 645 ? O SER A 645 G 1 2 O LYS A 669 ? O LYS A 669 N LEU A 651 ? N LEU A 651 G 2 3 N LEU A 652 ? N LEU A 652 O VAL A 745 ? O VAL A 745 G 3 4 N LEU A 746 ? N LEU A 746 O SER A 757 ? O SER A 757 G 4 5 N SER A 754 ? N SER A 754 O MET A 769 ? O MET A 769 G 5 6 N ILE A 768 ? N ILE A 768 O GLU A 775 ? O GLU A 775 G 6 7 N VAL A 780 ? N VAL A 780 O VAL A 888 ? O VAL A 888 G 7 8 O VAL A 895 ? O VAL A 895 N THR A 845 ? N THR A 845 G 8 9 O LEU A 846 ? O LEU A 846 N MET A 835 ? N MET A 835 G 9 10 O PHE A 836 ? O PHE A 836 N TYR A 805 ? N TYR A 805 G 10 11 N PHE A 804 ? N PHE A 804 O ARG A 816 ? O ARG A 816 G 11 12 N PHE A 813 ? N PHE A 813 O GLY A 912 ? O GLY A 912 H 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 H 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 H 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 H 4 5 N LYS A 714 ? N LYS A 714 O SER A 736 ? O SER A 736 I 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 I 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 I 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 I 4 5 N LYS A 711 ? N LYS A 711 O ARG A 793 ? O ARG A 793 I 5 6 N ILE A 790 ? N ILE A 790 O GLN A 866 ? O GLN A 866 I 6 7 O MET A 865 ? O MET A 865 N GLY A 853 ? N GLY A 853 I 7 8 O GLY A 854 ? O GLY A 854 N TYR A 829 ? N TYR A 829 J 1 2 N ARG A 963 ? N ARG A 963 O GLY A 976 ? O GLY A 976 J 2 3 N LEU A 979 ? N LEU A 979 O ALA A 1037 ? O ALA A 1037 J 3 4 O SER A 1042 ? O SER A 1042 N ALA A 1007 ? N ALA A 1007 J 4 5 N ARG A 1011 ? N ARG A 1011 O LEU A 1020 ? O LEU A 1020 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG A 1802' AC2 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE PO4 A 1803' AC3 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE ZN A 1805' AC4 Software ? ? ? ? 15 'BINDING SITE FOR RESIDUE GB1 A 1804' AC5 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE MPD A 1801' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 1 ASN A 194 ? ASN A 194 . ? 1_555 ? 2 AC2 9 ARG A 770 ? ARG A 770 . ? 1_555 ? 3 AC2 9 ARG A 893 ? ARG A 893 . ? 1_555 ? 4 AC2 9 SER A 924 ? SER A 924 . ? 1_555 ? 5 AC2 9 HOH G . ? HOH A 1939 . ? 1_555 ? 6 AC2 9 HOH G . ? HOH A 1941 . ? 1_555 ? 7 AC2 9 HOH G . ? HOH A 1942 . ? 1_555 ? 8 AC2 9 HOH G . ? HOH A 2909 . ? 1_555 ? 9 AC2 9 HOH G . ? HOH A 2926 . ? 1_555 ? 10 AC2 9 HOH G . ? HOH A 2933 . ? 1_555 ? 11 AC3 5 HIS A 90 ? HIS A 90 . ? 1_555 ? 12 AC3 5 ASP A 92 ? ASP A 92 . ? 1_555 ? 13 AC3 5 ASP A 204 ? ASP A 204 . ? 1_555 ? 14 AC3 5 HIS A 471 ? HIS A 471 . ? 1_555 ? 15 AC3 5 GB1 E . ? GB1 A 1804 . ? 1_555 ? 16 AC4 15 HIS A 90 ? HIS A 90 . ? 1_555 ? 17 AC4 15 ASP A 92 ? ASP A 92 . ? 1_555 ? 18 AC4 15 TRP A 95 ? TRP A 95 . ? 1_555 ? 19 AC4 15 ASP A 204 ? ASP A 204 . ? 1_555 ? 20 AC4 15 ARG A 228 ? ARG A 228 . ? 1_555 ? 21 AC4 15 TYR A 269 ? TYR A 269 . ? 1_555 ? 22 AC4 15 ASP A 340 ? ASP A 340 . ? 1_555 ? 23 AC4 15 ASP A 341 ? ASP A 341 . ? 1_555 ? 24 AC4 15 HIS A 471 ? HIS A 471 . ? 1_555 ? 25 AC4 15 ASP A 472 ? ASP A 472 . ? 1_555 ? 26 AC4 15 TYR A 727 ? TYR A 727 . ? 1_555 ? 27 AC4 15 GLY A 877 ? GLY A 877 . ? 1_555 ? 28 AC4 15 ZN D . ? ZN A 1805 . ? 1_555 ? 29 AC4 15 HOH G . ? HOH A 2498 . ? 1_555 ? 30 AC4 15 HOH G . ? HOH A 2723 . ? 1_555 ? 31 AC5 7 LYS A 63 ? LYS A 63 . ? 1_555 ? 32 AC5 7 GLN A 64 ? GLN A 64 . ? 1_555 ? 33 AC5 7 HIS A 273 ? HIS A 273 . ? 1_555 ? 34 AC5 7 HOH G . ? HOH A 2362 . ? 1_555 ? 35 AC5 7 HOH G . ? HOH A 2513 . ? 1_555 ? 36 AC5 7 HOH G . ? HOH A 2514 . ? 1_555 ? 37 AC5 7 HOH G . ? HOH A 2516 . ? 1_555 ? # _database_PDB_matrix.entry_id 2F18 _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 2F18 _atom_sites.fract_transf_matrix[1][1] 0.014500 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009114 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007199 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O P S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . CYS A 1 31 ? 44.158 35.938 -18.994 1.00 23.70 ? 31 CYS A N 1 ATOM 2 C CA . CYS A 1 31 ? 43.409 37.162 -18.573 1.00 21.88 ? 31 CYS A CA 1 ATOM 3 C C . CYS A 1 31 ? 41.909 36.957 -18.632 1.00 20.75 ? 31 CYS A C 1 ATOM 4 O O . CYS A 1 31 ? 41.396 36.384 -19.619 1.00 21.80 ? 31 CYS A O 1 ATOM 5 C CB . CYS A 1 31 ? 43.715 38.327 -19.514 1.00 21.45 ? 31 CYS A CB 1 ATOM 6 S SG . CYS A 1 31 ? 45.415 38.987 -19.520 1.00 23.16 ? 31 CYS A SG 1 ATOM 7 N N . GLN A 1 32 ? 41.196 37.485 -17.642 1.00 19.69 ? 32 GLN A N 1 ATOM 8 C CA . GLN A 1 32 ? 39.740 37.416 -17.614 1.00 19.41 ? 32 GLN A CA 1 ATOM 9 C C . GLN A 1 32 ? 39.227 38.341 -18.722 1.00 17.41 ? 32 GLN A C 1 ATOM 10 O O . GLN A 1 32 ? 39.822 39.398 -19.013 1.00 15.53 ? 32 GLN A O 1 ATOM 11 C CB . GLN A 1 32 ? 39.162 37.968 -16.306 1.00 21.41 ? 32 GLN A CB 1 ATOM 12 C CG . GLN A 1 32 ? 39.303 37.107 -15.086 1.00 23.15 ? 32 GLN A CG 1 ATOM 13 C CD . GLN A 1 32 ? 38.210 37.416 -14.050 1.00 24.58 ? 32 GLN A CD 1 ATOM 14 O OE1 . GLN A 1 32 ? 37.101 36.866 -14.120 1.00 25.63 ? 32 GLN A OE1 1 ATOM 15 N NE2 . GLN A 1 32 ? 38.515 38.314 -13.098 1.00 25.11 ? 32 GLN A NE2 1 ATOM 16 N N . ASP A 1 33 ? 38.114 37.941 -19.336 1.00 17.53 ? 33 ASP A N 1 ATOM 17 C CA . ASP A 1 33 ? 37.478 38.750 -20.375 1.00 15.89 ? 33 ASP A CA 1 ATOM 18 C C . ASP A 1 33 ? 36.564 39.742 -19.624 1.00 16.10 ? 33 ASP A C 1 ATOM 19 O O . ASP A 1 33 ? 35.588 39.350 -18.983 1.00 18.04 ? 33 ASP A O 1 ATOM 20 C CB . ASP A 1 33 ? 36.664 37.812 -21.284 1.00 16.78 ? 33 ASP A CB 1 ATOM 21 C CG . ASP A 1 33 ? 36.008 38.521 -22.451 1.00 18.63 ? 33 ASP A CG 1 ATOM 22 O OD1 . ASP A 1 33 ? 35.554 39.683 -22.326 1.00 18.36 ? 33 ASP A OD1 1 ATOM 23 O OD2 . ASP A 1 33 ? 35.885 37.872 -23.529 1.00 20.60 ? 33 ASP A OD2 1 ATOM 24 N N . VAL A 1 34 ? 36.832 41.041 -19.743 1.00 12.28 ? 34 VAL A N 1 ATOM 25 C CA . VAL A 1 34 ? 36.036 42.006 -19.012 1.00 10.78 ? 34 VAL A CA 1 ATOM 26 C C . VAL A 1 34 ? 34.857 42.578 -19.765 1.00 9.90 ? 34 VAL A C 1 ATOM 27 O O . VAL A 1 34 ? 34.160 43.434 -19.261 1.00 10.31 ? 34 VAL A O 1 ATOM 28 C CB . VAL A 1 34 ? 36.915 43.165 -18.512 1.00 11.39 ? 34 VAL A CB 1 ATOM 29 C CG1 . VAL A 1 34 ? 38.169 42.593 -17.807 1.00 13.47 ? 34 VAL A CG1 1 ATOM 30 C CG2 . VAL A 1 34 ? 37.381 44.074 -19.719 1.00 11.97 ? 34 VAL A CG2 1 ATOM 31 N N . VAL A 1 35 ? 34.611 42.002 -20.954 1.00 11.22 ? 35 VAL A N 1 ATOM 32 C CA . VAL A 1 35 ? 33.506 42.462 -21.795 1.00 11.28 ? 35 VAL A CA 1 ATOM 33 C C . VAL A 1 35 ? 32.330 41.512 -21.999 1.00 11.49 ? 35 VAL A C 1 ATOM 34 O O . VAL A 1 35 ? 31.170 41.898 -21.910 1.00 11.16 ? 35 VAL A O 1 ATOM 35 C CB . VAL A 1 35 ? 34.018 42.785 -23.198 1.00 11.48 ? 35 VAL A CB 1 ATOM 36 C CG1 . VAL A 1 35 ? 32.870 43.199 -24.127 1.00 12.59 ? 35 VAL A CG1 1 ATOM 37 C CG2 . VAL A 1 35 ? 35.103 43.929 -23.090 1.00 13.23 ? 35 VAL A CG2 1 ATOM 38 N N . GLN A 1 36 ? 32.661 40.250 -22.264 1.00 12.89 ? 36 GLN A N 1 ATOM 39 C CA . GLN A 1 36 ? 31.670 39.263 -22.714 1.00 14.33 ? 36 GLN A CA 1 ATOM 40 C C . GLN A 1 36 ? 31.066 38.360 -21.676 1.00 16.54 ? 36 GLN A C 1 ATOM 41 O O . GLN A 1 36 ? 30.121 37.654 -21.972 1.00 19.92 ? 36 GLN A O 1 ATOM 42 C CB . GLN A 1 36 ? 32.349 38.419 -23.794 1.00 14.51 ? 36 GLN A CB 1 ATOM 43 C CG . GLN A 1 36 ? 33.010 39.264 -24.879 1.00 16.16 ? 36 GLN A CG 1 ATOM 44 C CD . GLN A 1 36 ? 33.474 38.441 -26.041 1.00 15.89 ? 36 GLN A CD 1 ATOM 45 O OE1 . GLN A 1 36 ? 32.730 38.254 -26.991 1.00 17.56 ? 36 GLN A OE1 1 ATOM 46 N NE2 . GLN A 1 36 ? 34.708 37.977 -25.988 1.00 16.63 ? 36 GLN A NE2 1 ATOM 47 N N . ASP A 1 37 ? 31.610 38.357 -20.467 1.00 16.91 ? 37 ASP A N 1 ATOM 48 C CA . ASP A 1 37 ? 31.097 37.502 -19.406 1.00 18.32 ? 37 ASP A CA 1 ATOM 49 C C . ASP A 1 37 ? 30.380 38.328 -18.304 1.00 16.55 ? 37 ASP A C 1 ATOM 50 O O . ASP A 1 37 ? 31.069 38.956 -17.481 1.00 19.67 ? 37 ASP A O 1 ATOM 51 C CB . ASP A 1 37 ? 32.274 36.692 -18.771 1.00 20.47 ? 37 ASP A CB 1 ATOM 52 C CG . ASP A 1 37 ? 32.905 35.651 -19.740 1.00 22.36 ? 37 ASP A CG 1 ATOM 53 O OD1 . ASP A 1 37 ? 32.136 34.983 -20.444 1.00 24.76 ? 37 ASP A OD1 1 ATOM 54 O OD2 . ASP A 1 37 ? 34.154 35.491 -19.784 1.00 23.84 ? 37 ASP A OD2 1 ATOM 55 N N . VAL A 1 38 ? 29.061 38.299 -18.259 1.00 16.08 ? 38 VAL A N 1 ATOM 56 C CA . VAL A 1 38 ? 28.319 39.040 -17.208 1.00 14.84 ? 38 VAL A CA 1 ATOM 57 C C . VAL A 1 38 ? 28.501 38.340 -15.860 1.00 15.18 ? 38 VAL A C 1 ATOM 58 O O . VAL A 1 38 ? 28.114 37.181 -15.711 1.00 15.47 ? 38 VAL A O 1 ATOM 59 C CB . VAL A 1 38 ? 26.809 39.153 -17.505 1.00 15.46 ? 38 VAL A CB 1 ATOM 60 C CG1 . VAL A 1 38 ? 26.080 39.883 -16.321 1.00 14.32 ? 38 VAL A CG1 1 ATOM 61 C CG2 . VAL A 1 38 ? 26.596 39.897 -18.876 1.00 16.84 ? 38 VAL A CG2 1 ATOM 62 N N . PRO A 1 39 ? 29.111 38.997 -14.866 1.00 13.88 ? 39 PRO A N 1 ATOM 63 C CA . PRO A 1 39 ? 29.276 38.297 -13.584 1.00 12.74 ? 39 PRO A CA 1 ATOM 64 C C . PRO A 1 39 ? 27.981 37.956 -12.920 1.00 12.72 ? 39 PRO A C 1 ATOM 65 O O . PRO A 1 39 ? 27.022 38.688 -12.992 1.00 13.60 ? 39 PRO A O 1 ATOM 66 C CB . PRO A 1 39 ? 30.050 39.293 -12.723 1.00 12.92 ? 39 PRO A CB 1 ATOM 67 C CG . PRO A 1 39 ? 30.818 40.134 -13.742 1.00 12.30 ? 39 PRO A CG 1 ATOM 68 C CD . PRO A 1 39 ? 29.837 40.287 -14.897 1.00 13.85 ? 39 PRO A CD 1 ATOM 69 N N . ASN A 1 40 ? 27.973 36.798 -12.236 1.00 13.76 ? 40 ASN A N 1 ATOM 70 C CA . ASN A 1 40 ? 26.821 36.404 -11.468 1.00 14.52 ? 40 ASN A CA 1 ATOM 71 C C . ASN A 1 40 ? 27.102 36.754 -10.000 1.00 13.51 ? 40 ASN A C 1 ATOM 72 O O . ASN A 1 40 ? 28.016 36.193 -9.356 1.00 14.97 ? 40 ASN A O 1 ATOM 73 C CB . ASN A 1 40 ? 26.550 34.900 -11.659 1.00 18.61 ? 40 ASN A CB 1 ATOM 74 C CG . ASN A 1 40 ? 25.507 34.369 -10.724 1.00 22.27 ? 40 ASN A CG 1 ATOM 75 O OD1 . ASN A 1 40 ? 24.455 34.991 -10.490 1.00 25.13 ? 40 ASN A OD1 1 ATOM 76 N ND2 . ASN A 1 40 ? 25.783 33.196 -10.164 1.00 25.68 ? 40 ASN A ND2 1 ATOM 77 N N . VAL A 1 41 ? 26.364 37.748 -9.528 1.00 12.30 ? 41 VAL A N 1 ATOM 78 C CA . VAL A 1 41 ? 26.514 38.229 -8.131 1.00 11.21 ? 41 VAL A CA 1 ATOM 79 C C . VAL A 1 41 ? 25.166 38.217 -7.453 1.00 11.42 ? 41 VAL A C 1 ATOM 80 O O . VAL A 1 41 ? 24.099 38.327 -8.075 1.00 12.81 ? 41 VAL A O 1 ATOM 81 C CB . VAL A 1 41 ? 27.137 39.671 -8.067 1.00 10.72 ? 41 VAL A CB 1 ATOM 82 C CG1 . VAL A 1 41 ? 28.583 39.616 -8.506 1.00 12.81 ? 41 VAL A CG1 1 ATOM 83 C CG2 . VAL A 1 41 ? 26.276 40.697 -8.931 1.00 11.66 ? 41 VAL A CG2 1 ATOM 84 N N . ASP A 1 42 ? 25.186 38.130 -6.120 1.00 10.59 ? 42 ASP A N 1 ATOM 85 C CA . ASP A 1 42 ? 23.925 38.123 -5.394 1.00 10.93 ? 42 ASP A CA 1 ATOM 86 C C . ASP A 1 42 ? 23.218 39.479 -5.401 1.00 11.09 ? 42 ASP A C 1 ATOM 87 O O . ASP A 1 42 ? 21.962 39.579 -5.407 1.00 12.24 ? 42 ASP A O 1 ATOM 88 C CB . ASP A 1 42 ? 24.134 37.674 -3.929 1.00 11.89 ? 42 ASP A CB 1 ATOM 89 C CG . ASP A 1 42 ? 24.699 36.281 -3.839 1.00 14.11 ? 42 ASP A CG 1 ATOM 90 O OD1 . ASP A 1 42 ? 24.073 35.357 -4.462 1.00 17.60 ? 42 ASP A OD1 1 ATOM 91 O OD2 . ASP A 1 42 ? 25.761 36.025 -3.214 1.00 14.36 ? 42 ASP A OD2 1 ATOM 92 N N . VAL A 1 43 ? 24.012 40.561 -5.329 1.00 10.26 ? 43 VAL A N 1 ATOM 93 C CA . VAL A 1 43 ? 23.478 41.916 -5.333 1.00 10.21 ? 43 VAL A CA 1 ATOM 94 C C . VAL A 1 43 ? 24.232 42.690 -6.421 1.00 9.72 ? 43 VAL A C 1 ATOM 95 O O . VAL A 1 43 ? 25.480 42.755 -6.394 1.00 10.15 ? 43 VAL A O 1 ATOM 96 C CB . VAL A 1 43 ? 23.713 42.625 -3.992 1.00 9.30 ? 43 VAL A CB 1 ATOM 97 C CG1 . VAL A 1 43 ? 23.092 44.017 -4.035 1.00 11.29 ? 43 VAL A CG1 1 ATOM 98 C CG2 . VAL A 1 43 ? 23.039 41.820 -2.839 1.00 11.78 ? 43 VAL A CG2 1 ATOM 99 N N . GLN A 1 44 ? 23.505 43.234 -7.399 1.00 9.14 ? 44 GLN A N 1 ATOM 100 C CA . GLN A 1 44 ? 24.131 44.038 -8.453 1.00 9.36 ? 44 GLN A CA 1 ATOM 101 C C . GLN A 1 44 ? 23.403 45.352 -8.308 1.00 8.83 ? 44 GLN A C 1 ATOM 102 O O . GLN A 1 44 ? 22.209 45.425 -8.452 1.00 9.35 ? 44 GLN A O 1 ATOM 103 C CB . GLN A 1 44 ? 23.932 43.377 -9.813 1.00 10.24 ? 44 GLN A CB 1 ATOM 104 C CG . GLN A 1 44 ? 25.010 43.802 -10.819 1.00 9.05 ? 44 GLN A CG 1 ATOM 105 C CD . GLN A 1 44 ? 25.068 45.309 -10.958 1.00 8.85 ? 44 GLN A CD 1 ATOM 106 O OE1 . GLN A 1 44 ? 24.058 45.950 -11.306 1.00 10.08 ? 44 GLN A OE1 1 ATOM 107 N NE2 . GLN A 1 44 ? 26.255 45.900 -10.668 1.00 8.63 ? 44 GLN A NE2 1 ATOM 108 N N . MET A 1 45 ? 24.138 46.417 -7.972 1.00 8.73 ? 45 MET A N 1 ATOM 109 C CA . MET A 1 45 ? 23.453 47.638 -7.596 1.00 8.59 ? 45 MET A CA 1 ATOM 110 C C . MET A 1 45 ? 22.535 48.318 -8.615 1.00 7.54 ? 45 MET A C 1 ATOM 111 O O . MET A 1 45 ? 21.556 48.946 -8.223 1.00 9.29 ? 45 MET A O 1 ATOM 112 C CB . MET A 1 45 ? 24.481 48.634 -7.017 1.00 8.13 ? 45 MET A CB 1 ATOM 113 C CG . MET A 1 45 ? 25.091 48.172 -5.681 1.00 9.51 ? 45 MET A CG 1 ATOM 114 S SD . MET A 1 45 ? 23.877 47.903 -4.364 1.00 10.70 ? 45 MET A SD 1 ATOM 115 C CE . MET A 1 45 ? 23.192 49.611 -4.226 1.00 12.98 ? 45 MET A CE 1 ATOM 116 N N . LEU A 1 46 ? 22.888 48.213 -9.888 1.00 8.52 ? 46 LEU A N 1 ATOM 117 C CA . LEU A 1 46 ? 22.024 48.813 -10.914 1.00 9.29 ? 46 LEU A CA 1 ATOM 118 C C . LEU A 1 46 ? 20.705 47.996 -10.933 1.00 9.98 ? 46 LEU A C 1 ATOM 119 O O . LEU A 1 46 ? 19.641 48.570 -11.056 1.00 10.02 ? 46 LEU A O 1 ATOM 120 C CB . LEU A 1 46 ? 22.714 48.759 -12.274 1.00 10.42 ? 46 LEU A CB 1 ATOM 121 C CG . LEU A 1 46 ? 21.896 49.498 -13.356 1.00 10.86 ? 46 LEU A CG 1 ATOM 122 C CD1 . LEU A 1 46 ? 21.946 51.049 -13.129 1.00 11.41 ? 46 LEU A CD1 1 ATOM 123 C CD2 . LEU A 1 46 ? 22.467 49.103 -14.705 1.00 11.10 ? 46 LEU A CD2 1 ATOM 124 N N . GLU A 1 47 ? 20.793 46.669 -10.795 1.00 9.98 ? 47 GLU A N 1 ATOM 125 C CA . GLU A 1 47 ? 19.571 45.836 -10.822 1.00 11.23 ? 47 GLU A CA 1 ATOM 126 C C . GLU A 1 47 ? 18.755 46.147 -9.596 1.00 11.49 ? 47 GLU A C 1 ATOM 127 O O . GLU A 1 47 ? 17.525 46.307 -9.649 1.00 12.15 ? 47 GLU A O 1 ATOM 128 C CB . GLU A 1 47 ? 19.975 44.366 -10.868 1.00 12.13 ? 47 GLU A CB 1 ATOM 129 C CG . GLU A 1 47 ? 18.823 43.385 -11.043 1.00 16.12 ? 47 GLU A CG 1 ATOM 130 C CD . GLU A 1 47 ? 18.038 43.109 -9.799 1.00 18.93 ? 47 GLU A CD 1 ATOM 131 O OE1 . GLU A 1 47 ? 18.532 43.238 -8.662 1.00 18.25 ? 47 GLU A OE1 1 ATOM 132 O OE2 . GLU A 1 47 ? 16.853 42.710 -9.918 1.00 21.93 ? 47 GLU A OE2 1 ATOM 133 N N . LEU A 1 48 ? 19.427 46.283 -8.462 1.00 10.41 ? 48 LEU A N 1 ATOM 134 C CA . LEU A 1 48 ? 18.740 46.591 -7.224 1.00 11.44 ? 48 LEU A CA 1 ATOM 135 C C . LEU A 1 48 ? 18.003 47.922 -7.343 1.00 10.95 ? 48 LEU A C 1 ATOM 136 O O . LEU A 1 48 ? 16.844 48.072 -6.977 1.00 12.98 ? 48 LEU A O 1 ATOM 137 C CB . LEU A 1 48 ? 19.730 46.654 -6.040 1.00 12.59 ? 48 LEU A CB 1 ATOM 138 C CG . LEU A 1 48 ? 19.050 46.786 -4.686 1.00 12.68 ? 48 LEU A CG 1 ATOM 139 C CD1 . LEU A 1 48 ? 18.160 45.555 -4.451 1.00 18.11 ? 48 LEU A CD1 1 ATOM 140 C CD2 . LEU A 1 48 ? 20.097 46.878 -3.551 1.00 16.69 ? 48 LEU A CD2 1 ATOM 141 N N . TYR A 1 49 ? 18.672 48.926 -7.880 1.00 10.26 ? 49 TYR A N 1 ATOM 142 C CA . TYR A 1 49 ? 18.017 50.202 -8.078 1.00 10.54 ? 49 TYR A CA 1 ATOM 143 C C . TYR A 1 49 ? 16.798 50.112 -8.995 1.00 11.00 ? 49 TYR A C 1 ATOM 144 O O . TYR A 1 49 ? 15.823 50.839 -8.775 1.00 11.37 ? 49 TYR A O 1 ATOM 145 C CB . TYR A 1 49 ? 19.062 51.191 -8.683 1.00 9.41 ? 49 TYR A CB 1 ATOM 146 C CG . TYR A 1 49 ? 19.649 52.120 -7.669 1.00 8.71 ? 49 TYR A CG 1 ATOM 147 C CD1 . TYR A 1 49 ? 20.079 51.628 -6.441 1.00 9.58 ? 49 TYR A CD1 1 ATOM 148 C CD2 . TYR A 1 49 ? 19.686 53.491 -7.903 1.00 9.99 ? 49 TYR A CD2 1 ATOM 149 C CE1 . TYR A 1 49 ? 20.513 52.488 -5.445 1.00 9.24 ? 49 TYR A CE1 1 ATOM 150 C CE2 . TYR A 1 49 ? 20.126 54.389 -6.897 1.00 9.13 ? 49 TYR A CE2 1 ATOM 151 C CZ . TYR A 1 49 ? 20.523 53.860 -5.671 1.00 9.03 ? 49 TYR A CZ 1 ATOM 152 O OH . TYR A 1 49 ? 20.887 54.701 -4.644 1.00 9.90 ? 49 TYR A OH 1 ATOM 153 N N . ASP A 1 50 ? 16.852 49.266 -10.021 1.00 10.88 ? 50 ASP A N 1 ATOM 154 C CA . ASP A 1 50 ? 15.719 49.197 -10.948 1.00 13.67 ? 50 ASP A CA 1 ATOM 155 C C . ASP A 1 50 ? 14.505 48.647 -10.199 1.00 14.20 ? 50 ASP A C 1 ATOM 156 O O . ASP A 1 50 ? 13.389 49.096 -10.504 1.00 14.90 ? 50 ASP A O 1 ATOM 157 C CB . ASP A 1 50 ? 16.123 48.276 -12.086 1.00 15.53 ? 50 ASP A CB 1 ATOM 158 C CG . ASP A 1 50 ? 15.329 48.464 -13.337 1.00 18.17 ? 50 ASP A CG 1 ATOM 159 O OD1 . ASP A 1 50 ? 14.624 49.468 -13.482 1.00 19.95 ? 50 ASP A OD1 1 ATOM 160 O OD2 . ASP A 1 50 ? 15.482 47.556 -14.189 1.00 22.44 ? 50 ASP A OD2 1 ATOM 161 N N . ARG A 1 51 ? 14.716 47.686 -9.303 1.00 14.10 ? 51 ARG A N 1 ATOM 162 C CA . ARG A 1 51 ? 13.606 47.029 -8.543 1.00 15.74 ? 51 ARG A CA 1 ATOM 163 C C . ARG A 1 51 ? 13.100 47.779 -7.309 1.00 15.90 ? 51 ARG A C 1 ATOM 164 O O . ARG A 1 51 ? 11.924 47.694 -6.978 1.00 17.83 ? 51 ARG A O 1 ATOM 165 C CB . ARG A 1 51 ? 14.021 45.636 -8.028 1.00 19.23 ? 51 ARG A CB 1 ATOM 166 C CG . ARG A 1 51 ? 14.645 44.714 -8.996 1.00 25.42 ? 51 ARG A CG 1 ATOM 167 C CD . ARG A 1 51 ? 14.923 43.316 -8.335 1.00 29.58 ? 51 ARG A CD 1 ATOM 168 N NE . ARG A 1 51 ? 14.840 43.359 -6.882 1.00 31.63 ? 51 ARG A NE 1 ATOM 169 C CZ . ARG A 1 51 ? 15.850 43.176 -6.034 1.00 32.76 ? 51 ARG A CZ 1 ATOM 170 N NH1 . ARG A 1 51 ? 17.084 42.916 -6.466 1.00 33.25 ? 51 ARG A NH1 1 ATOM 171 N NH2 . ARG A 1 51 ? 15.615 43.278 -4.729 1.00 33.58 ? 51 ARG A NH2 1 ATOM 172 N N . MET A 1 52 ? 13.993 48.507 -6.650 1.00 14.48 ? 52 MET A N 1 ATOM 173 C CA . MET A 1 52 ? 13.654 49.233 -5.437 1.00 14.08 ? 52 MET A CA 1 ATOM 174 C C . MET A 1 52 ? 12.626 50.310 -5.604 1.00 13.61 ? 52 MET A C 1 ATOM 175 O O . MET A 1 52 ? 12.612 51.010 -6.619 1.00 14.55 ? 52 MET A O 1 ATOM 176 C CB A MET A 1 52 ? 14.908 49.878 -4.846 0.50 12.75 ? 52 MET A CB 1 ATOM 177 C CB B MET A 1 52 ? 14.730 49.718 -4.571 0.50 15.75 ? 52 MET A CB 1 ATOM 178 C CG A MET A 1 52 ? 15.817 48.883 -4.208 0.50 12.51 ? 52 MET A CG 1 ATOM 179 C CG B MET A 1 52 ? 15.425 48.628 -3.783 0.50 17.44 ? 52 MET A CG 1 ATOM 180 S SD A MET A 1 52 ? 17.340 49.672 -3.603 0.50 11.81 ? 52 MET A SD 1 ATOM 181 S SD B MET A 1 52 ? 16.547 49.282 -2.579 0.50 19.47 ? 52 MET A SD 1 ATOM 182 C CE A MET A 1 52 ? 16.742 50.995 -2.533 0.50 11.47 ? 52 MET A CE 1 ATOM 183 C CE B MET A 1 52 ? 17.694 49.958 -3.742 0.50 18.64 ? 52 MET A CE 1 ATOM 184 N N . SER A 1 53 ? 11.787 50.481 -4.574 1.00 14.09 ? 53 SER A N 1 ATOM 185 C CA . SER A 1 53 ? 10.757 51.512 -4.611 1.00 14.87 ? 53 SER A CA 1 ATOM 186 C C . SER A 1 53 ? 11.177 52.866 -4.005 1.00 14.66 ? 53 SER A C 1 ATOM 187 O O . SER A 1 53 ? 10.561 53.907 -4.271 1.00 15.35 ? 53 SER A O 1 ATOM 188 C CB A SER A 1 53 ? 9.504 50.978 -3.896 0.50 15.18 ? 53 SER A CB 1 ATOM 189 C CB B SER A 1 53 ? 9.329 51.237 -4.105 0.50 15.23 ? 53 SER A CB 1 ATOM 190 O OG A SER A 1 53 ? 8.984 49.904 -4.648 0.50 17.95 ? 53 SER A OG 1 ATOM 191 O OG B SER A 1 53 ? 9.411 50.957 -2.720 0.50 16.66 ? 53 SER A OG 1 ATOM 192 N N . PHE A 1 54 ? 12.196 52.847 -3.155 1.00 13.87 ? 54 PHE A N 1 ATOM 193 C CA . PHE A 1 54 ? 12.680 54.045 -2.510 1.00 12.73 ? 54 PHE A CA 1 ATOM 194 C C . PHE A 1 54 ? 11.643 54.839 -1.712 1.00 13.40 ? 54 PHE A C 1 ATOM 195 O O . PHE A 1 54 ? 11.716 56.079 -1.572 1.00 13.84 ? 54 PHE A O 1 ATOM 196 C CB . PHE A 1 54 ? 13.354 55.005 -3.536 1.00 12.84 ? 54 PHE A CB 1 ATOM 197 C CG . PHE A 1 54 ? 14.617 54.452 -4.178 1.00 10.68 ? 54 PHE A CG 1 ATOM 198 C CD1 . PHE A 1 54 ? 14.545 53.615 -5.273 1.00 12.34 ? 54 PHE A CD1 1 ATOM 199 C CD2 . PHE A 1 54 ? 15.864 54.796 -3.675 1.00 11.33 ? 54 PHE A CD2 1 ATOM 200 C CE1 . PHE A 1 54 ? 15.723 53.121 -5.864 1.00 11.19 ? 54 PHE A CE1 1 ATOM 201 C CE2 . PHE A 1 54 ? 17.035 54.324 -4.268 1.00 12.81 ? 54 PHE A CE2 1 ATOM 202 C CZ . PHE A 1 54 ? 16.971 53.486 -5.358 1.00 11.86 ? 54 PHE A CZ 1 ATOM 203 N N . LYS A 1 55 ? 10.656 54.131 -1.159 1.00 14.96 ? 55 LYS A N 1 ATOM 204 C CA . LYS A 1 55 ? 9.693 54.881 -0.356 1.00 15.49 ? 55 LYS A CA 1 ATOM 205 C C . LYS A 1 55 ? 10.266 55.325 0.953 1.00 15.18 ? 55 LYS A C 1 ATOM 206 O O . LYS A 1 55 ? 10.961 54.569 1.622 1.00 17.79 ? 55 LYS A O 1 ATOM 207 C CB . LYS A 1 55 ? 8.452 54.034 -0.037 1.00 16.38 ? 55 LYS A CB 1 ATOM 208 C CG . LYS A 1 55 ? 7.702 53.589 -1.246 1.00 18.60 ? 55 LYS A CG 1 ATOM 209 C CD . LYS A 1 55 ? 7.427 54.748 -2.218 1.00 19.82 ? 55 LYS A CD 1 ATOM 210 C CE . LYS A 1 55 ? 6.579 54.269 -3.417 1.00 21.17 ? 55 LYS A CE 1 ATOM 211 N NZ . LYS A 1 55 ? 6.243 55.420 -4.341 1.00 22.93 ? 55 LYS A NZ 1 ATOM 212 N N . ASP A 1 56 ? 9.989 56.558 1.322 1.00 15.08 ? 56 ASP A N 1 ATOM 213 C CA . ASP A 1 56 ? 10.500 57.137 2.529 1.00 15.90 ? 56 ASP A CA 1 ATOM 214 C C . ASP A 1 56 ? 9.460 57.149 3.662 1.00 16.80 ? 56 ASP A C 1 ATOM 215 O O . ASP A 1 56 ? 8.839 58.163 3.969 1.00 19.03 ? 56 ASP A O 1 ATOM 216 C CB . ASP A 1 56 ? 11.010 58.549 2.185 1.00 15.80 ? 56 ASP A CB 1 ATOM 217 C CG . ASP A 1 56 ? 11.671 59.253 3.361 1.00 15.67 ? 56 ASP A CG 1 ATOM 218 O OD1 . ASP A 1 56 ? 12.203 58.617 4.296 1.00 15.52 ? 56 ASP A OD1 1 ATOM 219 O OD2 . ASP A 1 56 ? 11.651 60.506 3.312 1.00 18.28 ? 56 ASP A OD2 1 ATOM 220 N N . ILE A 1 57 ? 9.293 56.011 4.297 1.00 17.44 ? 57 ILE A N 1 ATOM 221 C CA . ILE A 1 57 ? 8.301 55.958 5.352 1.00 19.08 ? 57 ILE A CA 1 ATOM 222 C C . ILE A 1 57 ? 8.898 55.942 6.716 1.00 19.00 ? 57 ILE A C 1 ATOM 223 O O . ILE A 1 57 ? 10.031 55.503 6.922 1.00 18.34 ? 57 ILE A O 1 ATOM 224 C CB . ILE A 1 57 ? 7.347 54.731 5.201 1.00 21.21 ? 57 ILE A CB 1 ATOM 225 C CG1 . ILE A 1 57 ? 8.128 53.443 5.247 1.00 22.27 ? 57 ILE A CG1 1 ATOM 226 C CG2 . ILE A 1 57 ? 6.512 54.827 3.864 1.00 21.00 ? 57 ILE A CG2 1 ATOM 227 C CD1 . ILE A 1 57 ? 7.289 52.316 5.846 1.00 23.16 ? 57 ILE A CD1 1 ATOM 228 N N . ASP A 1 58 ? 8.117 56.425 7.664 1.00 18.39 ? 58 ASP A N 1 ATOM 229 C CA . ASP A 1 58 ? 8.504 56.501 9.048 1.00 18.97 ? 58 ASP A CA 1 ATOM 230 C C . ASP A 1 58 ? 8.530 55.094 9.613 1.00 18.48 ? 58 ASP A C 1 ATOM 231 O O . ASP A 1 58 ? 7.485 54.482 9.792 1.00 18.85 ? 58 ASP A O 1 ATOM 232 C CB . ASP A 1 58 ? 7.468 57.350 9.769 1.00 20.13 ? 58 ASP A CB 1 ATOM 233 C CG . ASP A 1 58 ? 7.843 57.643 11.183 1.00 22.79 ? 58 ASP A CG 1 ATOM 234 O OD1 . ASP A 1 58 ? 8.649 56.889 11.786 1.00 21.24 ? 58 ASP A OD1 1 ATOM 235 O OD2 . ASP A 1 58 ? 7.320 58.668 11.706 1.00 25.86 ? 58 ASP A OD2 1 ATOM 236 N N . GLY A 1 59 ? 9.711 54.550 9.872 1.00 17.24 ? 59 GLY A N 1 ATOM 237 C CA . GLY A 1 59 ? 9.806 53.195 10.397 1.00 16.64 ? 59 GLY A CA 1 ATOM 238 C C . GLY A 1 59 ? 9.753 53.080 11.922 1.00 14.89 ? 59 GLY A C 1 ATOM 239 O O . GLY A 1 59 ? 9.984 51.993 12.453 1.00 15.83 ? 59 GLY A O 1 ATOM 240 N N . GLY A 1 60 ? 9.479 54.194 12.595 1.00 14.90 ? 60 GLY A N 1 ATOM 241 C CA . GLY A 1 60 ? 9.462 54.202 14.050 1.00 14.42 ? 60 GLY A CA 1 ATOM 242 C C . GLY A 1 60 ? 10.748 54.805 14.650 1.00 13.27 ? 60 GLY A C 1 ATOM 243 O O . GLY A 1 60 ? 11.299 55.774 14.096 1.00 15.02 ? 60 GLY A O 1 ATOM 244 N N . VAL A 1 61 ? 11.206 54.282 15.790 1.00 13.85 ? 61 VAL A N 1 ATOM 245 C CA . VAL A 1 61 ? 12.410 54.850 16.396 1.00 12.97 ? 61 VAL A CA 1 ATOM 246 C C . VAL A 1 61 ? 13.572 54.727 15.371 1.00 12.79 ? 61 VAL A C 1 ATOM 247 O O . VAL A 1 61 ? 14.430 55.624 15.341 1.00 12.86 ? 61 VAL A O 1 ATOM 248 C CB . VAL A 1 61 ? 12.775 54.192 17.745 1.00 13.63 ? 61 VAL A CB 1 ATOM 249 C CG1 . VAL A 1 61 ? 11.719 54.567 18.811 1.00 14.38 ? 61 VAL A CG1 1 ATOM 250 C CG2 . VAL A 1 61 ? 12.917 52.702 17.600 1.00 15.27 ? 61 VAL A CG2 1 ATOM 251 N N . TRP A 1 62 ? 13.627 53.657 14.589 1.00 12.26 ? 62 TRP A N 1 ATOM 252 C CA . TRP A 1 62 ? 14.657 53.581 13.502 1.00 11.66 ? 62 TRP A CA 1 ATOM 253 C C . TRP A 1 62 ? 13.862 54.228 12.392 1.00 11.55 ? 62 TRP A C 1 ATOM 254 O O . TRP A 1 62 ? 13.077 53.560 11.679 1.00 12.46 ? 62 TRP A O 1 ATOM 255 C CB . TRP A 1 62 ? 15.007 52.137 13.157 1.00 11.01 ? 62 TRP A CB 1 ATOM 256 C CG . TRP A 1 62 ? 15.983 52.015 12.052 1.00 10.18 ? 62 TRP A CG 1 ATOM 257 C CD1 . TRP A 1 62 ? 16.671 53.056 11.432 1.00 10.50 ? 62 TRP A CD1 1 ATOM 258 C CD2 . TRP A 1 62 ? 16.337 50.822 11.379 1.00 10.59 ? 62 TRP A CD2 1 ATOM 259 N NE1 . TRP A 1 62 ? 17.408 52.544 10.412 1.00 10.75 ? 62 TRP A NE1 1 ATOM 260 C CE2 . TRP A 1 62 ? 17.243 51.181 10.348 1.00 10.36 ? 62 TRP A CE2 1 ATOM 261 C CE3 . TRP A 1 62 ? 15.979 49.477 11.531 1.00 10.36 ? 62 TRP A CE3 1 ATOM 262 C CZ2 . TRP A 1 62 ? 17.801 50.230 9.464 1.00 10.89 ? 62 TRP A CZ2 1 ATOM 263 C CZ3 . TRP A 1 62 ? 16.514 48.537 10.673 1.00 9.94 ? 62 TRP A CZ3 1 ATOM 264 C CH2 . TRP A 1 62 ? 17.434 48.914 9.635 1.00 11.12 ? 62 TRP A CH2 1 ATOM 265 N N . LYS A 1 63 ? 14.065 55.533 12.210 1.00 11.88 ? 63 LYS A N 1 ATOM 266 C CA . LYS A 1 63 ? 13.200 56.273 11.276 1.00 13.49 ? 63 LYS A CA 1 ATOM 267 C C . LYS A 1 63 ? 13.152 55.783 9.851 1.00 13.22 ? 63 LYS A C 1 ATOM 268 O O . LYS A 1 63 ? 12.119 55.878 9.158 1.00 14.10 ? 63 LYS A O 1 ATOM 269 C CB . LYS A 1 63 ? 13.555 57.756 11.300 1.00 14.15 ? 63 LYS A CB 1 ATOM 270 C CG . LYS A 1 63 ? 13.132 58.494 12.607 1.00 18.82 ? 63 LYS A CG 1 ATOM 271 C CD . LYS A 1 63 ? 11.602 58.852 12.645 1.00 21.32 ? 63 LYS A CD 1 ATOM 272 C CE . LYS A 1 63 ? 11.108 59.434 14.034 1.00 24.98 ? 63 LYS A CE 1 ATOM 273 N NZ . LYS A 1 63 ? 11.376 58.692 15.387 1.00 26.21 ? 63 LYS A NZ 1 ATOM 274 N N . GLN A 1 64 ? 14.260 55.240 9.390 1.00 11.98 ? 64 GLN A N 1 ATOM 275 C CA . GLN A 1 64 ? 14.342 54.775 8.019 1.00 11.10 ? 64 GLN A CA 1 ATOM 276 C C . GLN A 1 64 ? 14.424 53.278 7.868 1.00 11.20 ? 64 GLN A C 1 ATOM 277 O O . GLN A 1 64 ? 14.735 52.766 6.799 1.00 11.17 ? 64 GLN A O 1 ATOM 278 C CB . GLN A 1 64 ? 15.558 55.467 7.327 1.00 11.48 ? 64 GLN A CB 1 ATOM 279 C CG . GLN A 1 64 ? 15.432 56.975 7.326 1.00 12.20 ? 64 GLN A CG 1 ATOM 280 C CD . GLN A 1 64 ? 16.817 57.653 7.181 1.00 10.46 ? 64 GLN A CD 1 ATOM 281 O OE1 . GLN A 1 64 ? 17.751 57.313 7.907 1.00 11.04 ? 64 GLN A OE1 1 ATOM 282 N NE2 . GLN A 1 64 ? 16.896 58.633 6.285 1.00 11.09 ? 64 GLN A NE2 1 ATOM 283 N N . GLY A 1 65 ? 14.044 52.579 8.947 1.00 11.66 ? 65 GLY A N 1 ATOM 284 C CA . GLY A 1 65 ? 14.009 51.119 8.960 1.00 12.10 ? 65 GLY A CA 1 ATOM 285 C C . GLY A 1 65 ? 12.656 50.555 9.386 1.00 12.61 ? 65 GLY A C 1 ATOM 286 O O . GLY A 1 65 ? 11.633 50.886 8.776 1.00 14.19 ? 65 GLY A O 1 ATOM 287 N N . TRP A 1 66 ? 12.704 49.686 10.381 1.00 13.22 ? 66 TRP A N 1 ATOM 288 C CA . TRP A 1 66 ? 11.445 49.088 10.908 1.00 12.68 ? 66 TRP A CA 1 ATOM 289 C C . TRP A 1 66 ? 11.721 48.714 12.340 1.00 13.58 ? 66 TRP A C 1 ATOM 290 O O . TRP A 1 66 ? 12.846 48.830 12.828 1.00 13.38 ? 66 TRP A O 1 ATOM 291 C CB . TRP A 1 66 ? 11.051 47.866 10.056 1.00 12.56 ? 66 TRP A CB 1 ATOM 292 C CG . TRP A 1 66 ? 11.998 46.710 10.211 1.00 12.30 ? 66 TRP A CG 1 ATOM 293 C CD1 . TRP A 1 66 ? 11.894 45.679 11.102 1.00 13.40 ? 66 TRP A CD1 1 ATOM 294 C CD2 . TRP A 1 66 ? 13.220 46.467 9.480 1.00 13.05 ? 66 TRP A CD2 1 ATOM 295 N NE1 . TRP A 1 66 ? 12.950 44.826 10.994 1.00 13.87 ? 66 TRP A NE1 1 ATOM 296 C CE2 . TRP A 1 66 ? 13.782 45.281 9.998 1.00 12.32 ? 66 TRP A CE2 1 ATOM 297 C CE3 . TRP A 1 66 ? 13.907 47.136 8.438 1.00 12.34 ? 66 TRP A CE3 1 ATOM 298 C CZ2 . TRP A 1 66 ? 14.981 44.739 9.530 1.00 14.31 ? 66 TRP A CZ2 1 ATOM 299 C CZ3 . TRP A 1 66 ? 15.100 46.584 7.984 1.00 13.25 ? 66 TRP A CZ3 1 ATOM 300 C CH2 . TRP A 1 66 ? 15.627 45.409 8.520 1.00 13.41 ? 66 TRP A CH2 1 ATOM 301 N N . ASN A 1 67 ? 10.690 48.264 13.074 1.00 14.53 ? 67 ASN A N 1 ATOM 302 C CA . ASN A 1 67 ? 10.877 47.858 14.483 1.00 14.47 ? 67 ASN A CA 1 ATOM 303 C C . ASN A 1 67 ? 11.478 46.452 14.494 1.00 14.56 ? 67 ASN A C 1 ATOM 304 O O . ASN A 1 67 ? 10.788 45.446 14.198 1.00 15.21 ? 67 ASN A O 1 ATOM 305 C CB . ASN A 1 67 ? 9.508 47.815 15.197 1.00 16.42 ? 67 ASN A CB 1 ATOM 306 C CG . ASN A 1 67 ? 8.907 49.162 15.393 1.00 19.06 ? 67 ASN A CG 1 ATOM 307 O OD1 . ASN A 1 67 ? 9.587 50.188 15.501 1.00 20.22 ? 67 ASN A OD1 1 ATOM 308 N ND2 . ASN A 1 67 ? 7.585 49.178 15.486 1.00 21.99 ? 67 ASN A ND2 1 ATOM 309 N N . ILE A 1 68 ? 12.775 46.382 14.771 1.00 13.09 ? 68 ILE A N 1 ATOM 310 C CA . ILE A 1 68 ? 13.473 45.126 14.768 1.00 14.13 ? 68 ILE A CA 1 ATOM 311 C C . ILE A 1 68 ? 13.015 44.225 15.922 1.00 15.10 ? 68 ILE A C 1 ATOM 312 O O . ILE A 1 68 ? 12.930 44.659 17.054 1.00 15.77 ? 68 ILE A O 1 ATOM 313 C CB . ILE A 1 68 ? 15.042 45.320 14.870 1.00 13.12 ? 68 ILE A CB 1 ATOM 314 C CG1 . ILE A 1 68 ? 15.543 46.157 13.667 1.00 12.82 ? 68 ILE A CG1 1 ATOM 315 C CG2 . ILE A 1 68 ? 15.731 43.952 14.909 1.00 14.04 ? 68 ILE A CG2 1 ATOM 316 C CD1 . ILE A 1 68 ? 17.030 46.626 13.892 1.00 12.47 ? 68 ILE A CD1 1 ATOM 317 N N . LYS A 1 69 ? 12.786 42.967 15.593 1.00 16.70 ? 69 LYS A N 1 ATOM 318 C CA . LYS A 1 69 ? 12.406 41.999 16.627 1.00 17.44 ? 69 LYS A CA 1 ATOM 319 C C . LYS A 1 69 ? 13.436 40.878 16.653 1.00 17.56 ? 69 LYS A C 1 ATOM 320 O O . LYS A 1 69 ? 14.022 40.549 15.630 1.00 17.23 ? 69 LYS A O 1 ATOM 321 C CB . LYS A 1 69 ? 11.013 41.426 16.311 1.00 21.00 ? 69 LYS A CB 1 ATOM 322 C CG . LYS A 1 69 ? 9.890 42.424 16.685 1.00 24.33 ? 69 LYS A CG 1 ATOM 323 C CD . LYS A 1 69 ? 8.494 42.012 16.137 1.00 29.04 ? 69 LYS A CD 1 ATOM 324 C CE . LYS A 1 69 ? 8.158 40.507 16.351 1.00 31.40 ? 69 LYS A CE 1 ATOM 325 N NZ . LYS A 1 69 ? 6.822 40.105 15.751 1.00 33.39 ? 69 LYS A NZ 1 ATOM 326 N N . TYR A 1 70 ? 13.703 40.311 17.830 1.00 17.54 ? 70 TYR A N 1 ATOM 327 C CA . TYR A 1 70 ? 14.638 39.178 17.853 1.00 17.67 ? 70 TYR A CA 1 ATOM 328 C C . TYR A 1 70 ? 14.102 38.106 18.808 1.00 18.95 ? 70 TYR A C 1 ATOM 329 O O . TYR A 1 70 ? 13.295 38.423 19.683 1.00 19.63 ? 70 TYR A O 1 ATOM 330 C CB . TYR A 1 70 ? 16.049 39.608 18.302 1.00 17.10 ? 70 TYR A CB 1 ATOM 331 C CG . TYR A 1 70 ? 16.113 40.237 19.660 1.00 16.01 ? 70 TYR A CG 1 ATOM 332 C CD1 . TYR A 1 70 ? 15.853 41.572 19.819 1.00 17.30 ? 70 TYR A CD1 1 ATOM 333 C CD2 . TYR A 1 70 ? 16.449 39.480 20.804 1.00 16.75 ? 70 TYR A CD2 1 ATOM 334 C CE1 . TYR A 1 70 ? 15.924 42.190 21.070 1.00 18.70 ? 70 TYR A CE1 1 ATOM 335 C CE2 . TYR A 1 70 ? 16.514 40.092 22.058 1.00 18.49 ? 70 TYR A CE2 1 ATOM 336 C CZ . TYR A 1 70 ? 16.250 41.438 22.189 1.00 18.76 ? 70 TYR A CZ 1 ATOM 337 O OH . TYR A 1 70 ? 16.263 42.060 23.435 1.00 20.98 ? 70 TYR A OH 1 ATOM 338 N N . ASP A 1 71 ? 14.541 36.873 18.579 1.00 20.80 ? 71 ASP A N 1 ATOM 339 C CA . ASP A 1 71 ? 14.181 35.734 19.413 1.00 22.65 ? 71 ASP A CA 1 ATOM 340 C C . ASP A 1 71 ? 15.149 35.710 20.586 1.00 23.36 ? 71 ASP A C 1 ATOM 341 O O . ASP A 1 71 ? 16.328 35.406 20.420 1.00 22.68 ? 71 ASP A O 1 ATOM 342 C CB . ASP A 1 71 ? 14.344 34.453 18.637 1.00 24.49 ? 71 ASP A CB 1 ATOM 343 C CG . ASP A 1 71 ? 13.897 33.231 19.453 1.00 26.61 ? 71 ASP A CG 1 ATOM 344 O OD1 . ASP A 1 71 ? 13.680 33.374 20.693 1.00 26.81 ? 71 ASP A OD1 1 ATOM 345 O OD2 . ASP A 1 71 ? 13.778 32.160 18.839 1.00 28.57 ? 71 ASP A OD2 1 ATOM 346 N N . PRO A 1 72 ? 14.668 36.021 21.803 1.00 24.84 ? 72 PRO A N 1 ATOM 347 C CA . PRO A 1 72 ? 15.610 36.000 22.924 1.00 25.35 ? 72 PRO A CA 1 ATOM 348 C C . PRO A 1 72 ? 16.379 34.691 23.109 1.00 25.33 ? 72 PRO A C 1 ATOM 349 O O . PRO A 1 72 ? 17.493 34.671 23.635 1.00 26.24 ? 72 PRO A O 1 ATOM 350 C CB . PRO A 1 72 ? 14.739 36.395 24.128 1.00 25.39 ? 72 PRO A CB 1 ATOM 351 C CG . PRO A 1 72 ? 13.348 35.977 23.714 1.00 26.66 ? 72 PRO A CG 1 ATOM 352 C CD . PRO A 1 72 ? 13.295 36.327 22.246 1.00 25.27 ? 72 PRO A CD 1 ATOM 353 N N . LEU A 1 73 ? 15.819 33.598 22.608 1.00 25.51 ? 73 LEU A N 1 ATOM 354 C CA . LEU A 1 73 ? 16.471 32.312 22.735 1.00 25.92 ? 73 LEU A CA 1 ATOM 355 C C . LEU A 1 73 ? 17.547 32.048 21.704 1.00 25.51 ? 73 LEU A C 1 ATOM 356 O O . LEU A 1 73 ? 18.146 30.987 21.703 1.00 25.78 ? 73 LEU A O 1 ATOM 357 C CB . LEU A 1 73 ? 15.427 31.204 22.634 1.00 26.38 ? 73 LEU A CB 1 ATOM 358 C CG . LEU A 1 73 ? 14.337 31.332 23.688 1.00 27.65 ? 73 LEU A CG 1 ATOM 359 C CD1 . LEU A 1 73 ? 13.275 30.232 23.466 1.00 28.37 ? 73 LEU A CD1 1 ATOM 360 C CD2 . LEU A 1 73 ? 15.003 31.229 25.059 1.00 28.43 ? 73 LEU A CD2 1 ATOM 361 N N . LYS A 1 74 ? 17.801 33.014 20.815 1.00 25.18 ? 74 LYS A N 1 ATOM 362 C CA . LYS A 1 74 ? 18.821 32.842 19.792 1.00 24.45 ? 74 LYS A CA 1 ATOM 363 C C . LYS A 1 74 ? 20.200 32.708 20.427 1.00 23.79 ? 74 LYS A C 1 ATOM 364 O O . LYS A 1 74 ? 21.074 31.992 19.928 1.00 23.34 ? 74 LYS A O 1 ATOM 365 C CB . LYS A 1 74 ? 18.820 34.054 18.864 1.00 24.73 ? 74 LYS A CB 1 ATOM 366 C CG . LYS A 1 74 ? 19.792 33.963 17.705 1.00 26.45 ? 74 LYS A CG 1 ATOM 367 C CD . LYS A 1 74 ? 19.627 35.245 16.863 1.00 27.79 ? 74 LYS A CD 1 ATOM 368 C CE . LYS A 1 74 ? 20.433 35.238 15.590 1.00 28.99 ? 74 LYS A CE 1 ATOM 369 N NZ . LYS A 1 74 ? 19.810 36.189 14.627 1.00 30.60 ? 74 LYS A NZ 1 ATOM 370 N N . TYR A 1 75 ? 20.446 33.458 21.494 1.00 24.18 ? 75 TYR A N 1 ATOM 371 C CA . TYR A 1 75 ? 21.745 33.380 22.160 1.00 23.75 ? 75 TYR A CA 1 ATOM 372 C C A TYR A 1 75 ? 21.534 32.667 23.509 0.50 23.82 ? 75 TYR A C 1 ATOM 373 C C B TYR A 1 75 ? 21.417 32.490 23.490 0.50 23.89 ? 75 TYR A C 1 ATOM 374 O O A TYR A 1 75 ? 20.537 32.899 24.184 0.50 24.15 ? 75 TYR A O 1 ATOM 375 O O B TYR A 1 75 ? 20.331 32.457 24.064 0.50 24.04 ? 75 TYR A O 1 ATOM 376 C CB A TYR A 1 75 ? 22.356 34.793 22.314 0.50 23.46 ? 75 TYR A CB 1 ATOM 377 C CB B TYR A 1 75 ? 22.044 34.724 22.712 0.50 23.73 ? 75 TYR A CB 1 ATOM 378 C CG A TYR A 1 75 ? 22.713 35.423 20.973 0.50 22.40 ? 75 TYR A CG 1 ATOM 379 C CG B TYR A 1 75 ? 22.037 35.649 21.562 0.50 22.86 ? 75 TYR A CG 1 ATOM 380 C CD1 A TYR A 1 75 ? 21.926 36.445 20.409 0.50 22.80 ? 75 TYR A CD1 1 ATOM 381 C CD1 B TYR A 1 75 ? 20.982 36.530 21.367 0.50 22.98 ? 75 TYR A CD1 1 ATOM 382 C CD2 A TYR A 1 75 ? 23.780 34.935 20.224 0.50 22.31 ? 75 TYR A CD2 1 ATOM 383 C CD2 B TYR A 1 75 ? 23.049 35.598 20.617 0.50 22.04 ? 75 TYR A CD2 1 ATOM 384 C CE1 A TYR A 1 75 ? 22.196 36.954 19.126 0.50 22.55 ? 75 TYR A CE1 1 ATOM 385 C CE1 B TYR A 1 75 ? 20.933 37.344 20.252 0.50 22.08 ? 75 TYR A CE1 1 ATOM 386 C CE2 A TYR A 1 75 ? 24.059 35.426 18.937 0.50 23.10 ? 75 TYR A CE2 1 ATOM 387 C CE2 B TYR A 1 75 ? 23.013 36.408 19.494 0.50 22.15 ? 75 TYR A CE2 1 ATOM 388 C CZ A TYR A 1 75 ? 23.268 36.429 18.391 0.50 22.42 ? 75 TYR A CZ 1 ATOM 389 C CZ B TYR A 1 75 ? 21.952 37.276 19.322 0.50 21.68 ? 75 TYR A CZ 1 ATOM 390 O OH A TYR A 1 75 ? 23.545 36.868 17.096 0.50 23.09 ? 75 TYR A OH 1 ATOM 391 O OH B TYR A 1 75 ? 21.924 38.069 18.215 0.50 20.71 ? 75 TYR A OH 1 ATOM 392 N N . ASN A 1 76 ? 22.465 31.774 23.845 1.00 23.21 ? 76 ASN A N 1 ATOM 393 C CA . ASN A 1 76 ? 22.429 30.952 25.053 1.00 24.37 ? 76 ASN A CA 1 ATOM 394 C C . ASN A 1 76 ? 23.878 30.658 25.498 1.00 24.67 ? 76 ASN A C 1 ATOM 395 O O . ASN A 1 76 ? 24.818 31.200 24.930 1.00 24.48 ? 76 ASN A O 1 ATOM 396 C CB . ASN A 1 76 ? 21.646 29.655 24.774 1.00 25.07 ? 76 ASN A CB 1 ATOM 397 C CG . ASN A 1 76 ? 22.145 28.915 23.563 1.00 24.91 ? 76 ASN A CG 1 ATOM 398 O OD1 . ASN A 1 76 ? 23.317 28.608 23.460 1.00 25.11 ? 76 ASN A OD1 1 ATOM 399 N ND2 . ASN A 1 76 ? 21.232 28.620 22.623 1.00 27.32 ? 76 ASN A ND2 1 ATOM 400 N N . ALA A 1 77 ? 24.087 29.807 26.512 1.00 25.62 ? 77 ALA A N 1 ATOM 401 C CA . ALA A 1 77 ? 25.455 29.575 26.995 1.00 26.63 ? 77 ALA A CA 1 ATOM 402 C C . ALA A 1 77 ? 26.432 29.074 25.946 1.00 27.23 ? 77 ALA A C 1 ATOM 403 O O . ALA A 1 77 ? 27.632 29.323 26.026 1.00 27.71 ? 77 ALA A O 1 ATOM 404 C CB . ALA A 1 77 ? 25.439 28.599 28.164 1.00 26.94 ? 77 ALA A CB 1 ATOM 405 N N . HIS A 1 78 ? 25.900 28.390 24.945 1.00 28.31 ? 78 HIS A N 1 ATOM 406 C CA . HIS A 1 78 ? 26.720 27.805 23.899 1.00 29.39 ? 78 HIS A CA 1 ATOM 407 C C . HIS A 1 78 ? 26.841 28.672 22.665 1.00 28.29 ? 78 HIS A C 1 ATOM 408 O O . HIS A 1 78 ? 27.656 28.402 21.767 1.00 28.75 ? 78 HIS A O 1 ATOM 409 C CB . HIS A 1 78 ? 26.143 26.434 23.545 1.00 32.62 ? 78 HIS A CB 1 ATOM 410 C CG . HIS A 1 78 ? 26.028 25.531 24.732 1.00 36.33 ? 78 HIS A CG 1 ATOM 411 N ND1 . HIS A 1 78 ? 27.131 25.080 25.431 1.00 38.27 ? 78 HIS A ND1 1 ATOM 412 C CD2 . HIS A 1 78 ? 24.943 25.058 25.393 1.00 37.75 ? 78 HIS A CD2 1 ATOM 413 C CE1 . HIS A 1 78 ? 26.731 24.369 26.472 1.00 39.14 ? 78 HIS A CE1 1 ATOM 414 N NE2 . HIS A 1 78 ? 25.407 24.341 26.473 1.00 39.46 ? 78 HIS A NE2 1 ATOM 415 N N . HIS A 1 79 ? 26.021 29.716 22.625 1.00 25.76 ? 79 HIS A N 1 ATOM 416 C CA . HIS A 1 79 ? 26.040 30.621 21.489 1.00 22.71 ? 79 HIS A CA 1 ATOM 417 C C . HIS A 1 79 ? 25.846 32.031 22.016 1.00 19.39 ? 79 HIS A C 1 ATOM 418 O O . HIS A 1 79 ? 24.733 32.495 22.101 1.00 18.96 ? 79 HIS A O 1 ATOM 419 C CB . HIS A 1 79 ? 24.913 30.283 20.550 1.00 23.55 ? 79 HIS A CB 1 ATOM 420 C CG . HIS A 1 79 ? 25.089 30.902 19.203 1.00 24.13 ? 79 HIS A CG 1 ATOM 421 N ND1 . HIS A 1 79 ? 24.206 31.828 18.687 1.00 25.56 ? 79 HIS A ND1 1 ATOM 422 C CD2 . HIS A 1 79 ? 26.082 30.773 18.289 1.00 24.80 ? 79 HIS A CD2 1 ATOM 423 C CE1 . HIS A 1 79 ? 24.651 32.249 17.516 1.00 24.80 ? 79 HIS A CE1 1 ATOM 424 N NE2 . HIS A 1 79 ? 25.786 31.626 17.251 1.00 24.44 ? 79 HIS A NE2 1 ATOM 425 N N . LYS A 1 80 ? 26.951 32.677 22.375 1.00 17.81 ? 80 LYS A N 1 ATOM 426 C CA . LYS A 1 80 ? 26.848 34.014 22.951 1.00 15.82 ? 80 LYS A CA 1 ATOM 427 C C . LYS A 1 80 ? 27.071 35.076 21.882 1.00 15.00 ? 80 LYS A C 1 ATOM 428 O O . LYS A 1 80 ? 27.659 34.794 20.815 1.00 16.30 ? 80 LYS A O 1 ATOM 429 C CB . LYS A 1 80 ? 27.904 34.216 24.021 1.00 17.57 ? 80 LYS A CB 1 ATOM 430 C CG . LYS A 1 80 ? 27.713 33.258 25.204 1.00 19.80 ? 80 LYS A CG 1 ATOM 431 C CD . LYS A 1 80 ? 28.896 33.315 26.113 1.00 22.73 ? 80 LYS A CD 1 ATOM 432 C CE . LYS A 1 80 ? 29.062 34.608 26.854 1.00 22.45 ? 80 LYS A CE 1 ATOM 433 N NZ . LYS A 1 80 ? 29.954 34.328 28.055 1.00 25.33 ? 80 LYS A NZ 1 ATOM 434 N N . LEU A 1 81 ? 26.556 36.261 22.153 1.00 12.99 ? 81 LEU A N 1 ATOM 435 C CA . LEU A 1 81 ? 26.787 37.397 21.254 1.00 11.77 ? 81 LEU A CA 1 ATOM 436 C C . LEU A 1 81 ? 28.082 38.063 21.722 1.00 12.42 ? 81 LEU A C 1 ATOM 437 O O . LEU A 1 81 ? 28.202 38.482 22.893 1.00 12.78 ? 81 LEU A O 1 ATOM 438 C CB . LEU A 1 81 ? 25.649 38.371 21.379 1.00 12.96 ? 81 LEU A CB 1 ATOM 439 C CG . LEU A 1 81 ? 25.793 39.642 20.508 1.00 12.16 ? 81 LEU A CG 1 ATOM 440 C CD1 . LEU A 1 81 ? 25.718 39.283 18.991 1.00 13.68 ? 81 LEU A CD1 1 ATOM 441 C CD2 . LEU A 1 81 ? 24.650 40.620 20.843 1.00 14.56 ? 81 LEU A CD2 1 ATOM 442 N N . LYS A 1 82 ? 29.066 38.179 20.826 1.00 10.76 ? 82 LYS A N 1 ATOM 443 C CA . LYS A 1 82 ? 30.355 38.770 21.130 1.00 10.92 ? 82 LYS A CA 1 ATOM 444 C C . LYS A 1 82 ? 30.296 40.194 20.609 1.00 11.45 ? 82 LYS A C 1 ATOM 445 O O . LYS A 1 82 ? 30.066 40.397 19.405 1.00 12.49 ? 82 LYS A O 1 ATOM 446 C CB . LYS A 1 82 ? 31.465 37.972 20.426 1.00 13.28 ? 82 LYS A CB 1 ATOM 447 C CG . LYS A 1 82 ? 32.871 38.493 20.641 1.00 20.17 ? 82 LYS A CG 1 ATOM 448 C CD . LYS A 1 82 ? 33.337 38.473 22.115 1.00 23.46 ? 82 LYS A CD 1 ATOM 449 C CE . LYS A 1 82 ? 34.851 38.103 22.180 1.00 25.31 ? 82 LYS A CE 1 ATOM 450 N NZ . LYS A 1 82 ? 35.399 38.171 23.573 1.00 27.97 ? 82 LYS A NZ 1 ATOM 451 N N . VAL A 1 83 ? 30.440 41.162 21.513 1.00 10.11 ? 83 VAL A N 1 ATOM 452 C CA . VAL A 1 83 ? 30.310 42.575 21.150 1.00 10.46 ? 83 VAL A CA 1 ATOM 453 C C . VAL A 1 83 ? 31.631 43.298 21.292 1.00 10.38 ? 83 VAL A C 1 ATOM 454 O O . VAL A 1 83 ? 32.261 43.292 22.350 1.00 10.80 ? 83 VAL A O 1 ATOM 455 C CB . VAL A 1 83 ? 29.279 43.243 22.073 1.00 8.82 ? 83 VAL A CB 1 ATOM 456 C CG1 . VAL A 1 83 ? 29.054 44.756 21.730 1.00 11.24 ? 83 VAL A CG1 1 ATOM 457 C CG2 . VAL A 1 83 ? 27.924 42.510 21.938 1.00 11.50 ? 83 VAL A CG2 1 ATOM 458 N N . PHE A 1 84 ? 32.049 43.970 20.213 1.00 9.90 ? 84 PHE A N 1 ATOM 459 C CA . PHE A 1 84 ? 33.275 44.773 20.230 1.00 9.92 ? 84 PHE A CA 1 ATOM 460 C C . PHE A 1 84 ? 32.910 46.230 20.154 1.00 9.79 ? 84 PHE A C 1 ATOM 461 O O . PHE A 1 84 ? 32.368 46.691 19.138 1.00 9.46 ? 84 PHE A O 1 ATOM 462 C CB . PHE A 1 84 ? 34.164 44.410 19.053 1.00 10.67 ? 84 PHE A CB 1 ATOM 463 C CG . PHE A 1 84 ? 34.773 43.089 19.201 1.00 11.71 ? 84 PHE A CG 1 ATOM 464 C CD1 . PHE A 1 84 ? 35.873 42.901 20.050 1.00 15.26 ? 84 PHE A CD1 1 ATOM 465 C CD2 . PHE A 1 84 ? 34.293 42.001 18.501 1.00 14.24 ? 84 PHE A CD2 1 ATOM 466 C CE1 . PHE A 1 84 ? 36.501 41.665 20.192 1.00 16.18 ? 84 PHE A CE1 1 ATOM 467 C CE2 . PHE A 1 84 ? 34.895 40.743 18.629 1.00 16.23 ? 84 PHE A CE2 1 ATOM 468 C CZ . PHE A 1 84 ? 36.017 40.553 19.466 1.00 15.67 ? 84 PHE A CZ 1 ATOM 469 N N . VAL A 1 85 ? 33.180 46.961 21.231 1.00 9.19 ? 85 VAL A N 1 ATOM 470 C CA . VAL A 1 85 ? 32.941 48.401 21.272 1.00 9.21 ? 85 VAL A CA 1 ATOM 471 C C . VAL A 1 85 ? 34.256 49.038 20.863 1.00 8.74 ? 85 VAL A C 1 ATOM 472 O O . VAL A 1 85 ? 35.269 48.867 21.516 1.00 9.42 ? 85 VAL A O 1 ATOM 473 C CB . VAL A 1 85 ? 32.507 48.862 22.692 1.00 8.82 ? 85 VAL A CB 1 ATOM 474 C CG1 . VAL A 1 85 ? 32.301 50.376 22.716 1.00 11.73 ? 85 VAL A CG1 1 ATOM 475 C CG2 . VAL A 1 85 ? 31.211 48.140 23.056 1.00 10.80 ? 85 VAL A CG2 1 ATOM 476 N N . VAL A 1 86 ? 34.228 49.795 19.747 1.00 8.96 ? 86 VAL A N 1 ATOM 477 C CA . VAL A 1 86 ? 35.457 50.307 19.135 1.00 8.48 ? 86 VAL A CA 1 ATOM 478 C C . VAL A 1 86 ? 35.532 51.834 19.229 1.00 8.01 ? 86 VAL A C 1 ATOM 479 O O . VAL A 1 86 ? 34.889 52.553 18.450 1.00 8.39 ? 86 VAL A O 1 ATOM 480 C CB . VAL A 1 86 ? 35.458 49.853 17.660 1.00 8.63 ? 86 VAL A CB 1 ATOM 481 C CG1 . VAL A 1 86 ? 36.794 50.369 16.984 1.00 9.65 ? 86 VAL A CG1 1 ATOM 482 C CG2 . VAL A 1 86 ? 35.427 48.312 17.567 1.00 10.77 ? 86 VAL A CG2 1 ATOM 483 N N . PRO A 1 87 ? 36.290 52.358 20.200 1.00 8.24 ? 87 PRO A N 1 ATOM 484 C CA . PRO A 1 87 ? 36.414 53.829 20.372 1.00 8.48 ? 87 PRO A CA 1 ATOM 485 C C . PRO A 1 87 ? 37.145 54.445 19.181 1.00 7.63 ? 87 PRO A C 1 ATOM 486 O O . PRO A 1 87 ? 38.153 53.889 18.698 1.00 7.85 ? 87 PRO A O 1 ATOM 487 C CB . PRO A 1 87 ? 37.224 53.975 21.698 1.00 8.11 ? 87 PRO A CB 1 ATOM 488 C CG . PRO A 1 87 ? 36.933 52.624 22.395 1.00 10.02 ? 87 PRO A CG 1 ATOM 489 C CD . PRO A 1 87 ? 36.986 51.621 21.269 1.00 9.22 ? 87 PRO A CD 1 ATOM 490 N N . HIS A 1 88 ? 36.636 55.585 18.739 1.00 7.28 ? 88 HIS A N 1 ATOM 491 C CA . HIS A 1 88 ? 37.219 56.275 17.562 1.00 8.08 ? 88 HIS A CA 1 ATOM 492 C C . HIS A 1 88 ? 36.977 57.752 17.639 1.00 7.85 ? 88 HIS A C 1 ATOM 493 O O . HIS A 1 88 ? 36.153 58.215 18.448 1.00 8.24 ? 88 HIS A O 1 ATOM 494 C CB . HIS A 1 88 ? 36.624 55.664 16.258 1.00 7.89 ? 88 HIS A CB 1 ATOM 495 C CG . HIS A 1 88 ? 35.193 56.001 16.013 1.00 6.65 ? 88 HIS A CG 1 ATOM 496 N ND1 . HIS A 1 88 ? 34.789 57.064 15.220 1.00 7.52 ? 88 HIS A ND1 1 ATOM 497 C CD2 . HIS A 1 88 ? 34.059 55.410 16.460 1.00 7.15 ? 88 HIS A CD2 1 ATOM 498 C CE1 . HIS A 1 88 ? 33.463 57.100 15.180 1.00 8.64 ? 88 HIS A CE1 1 ATOM 499 N NE2 . HIS A 1 88 ? 33.000 56.102 15.939 1.00 8.79 ? 88 HIS A NE2 1 ATOM 500 N N . SER A 1 89 ? 37.693 58.529 16.813 1.00 8.16 ? 89 SER A N 1 ATOM 501 C CA . SER A 1 89 ? 37.574 59.988 16.809 1.00 8.01 ? 89 SER A CA 1 ATOM 502 C C . SER A 1 89 ? 37.740 60.410 15.349 1.00 7.32 ? 89 SER A C 1 ATOM 503 O O . SER A 1 89 ? 38.831 60.215 14.786 1.00 8.07 ? 89 SER A O 1 ATOM 504 C CB . SER A 1 89 ? 38.718 60.530 17.674 1.00 9.10 ? 89 SER A CB 1 ATOM 505 O OG . SER A 1 89 ? 38.717 61.943 17.696 1.00 8.56 ? 89 SER A OG 1 ATOM 506 N N . HIS A 1 90 ? 36.698 60.983 14.783 1.00 7.12 ? 90 HIS A N 1 ATOM 507 C CA . HIS A 1 90 ? 36.755 61.388 13.371 1.00 7.04 ? 90 HIS A CA 1 ATOM 508 C C . HIS A 1 90 ? 37.430 62.770 13.276 1.00 7.20 ? 90 HIS A C 1 ATOM 509 O O . HIS A 1 90 ? 36.908 63.774 13.767 1.00 7.59 ? 90 HIS A O 1 ATOM 510 C CB . HIS A 1 90 ? 35.331 61.377 12.788 1.00 7.80 ? 90 HIS A CB 1 ATOM 511 C CG . HIS A 1 90 ? 35.292 61.730 11.333 1.00 6.78 ? 90 HIS A CG 1 ATOM 512 N ND1 . HIS A 1 90 ? 35.887 60.941 10.359 1.00 7.10 ? 90 HIS A ND1 1 ATOM 513 C CD2 . HIS A 1 90 ? 34.721 62.769 10.707 1.00 6.93 ? 90 HIS A CD2 1 ATOM 514 C CE1 . HIS A 1 90 ? 35.643 61.505 9.171 1.00 7.30 ? 90 HIS A CE1 1 ATOM 515 N NE2 . HIS A 1 90 ? 34.947 62.615 9.360 1.00 6.62 ? 90 HIS A NE2 1 ATOM 516 N N . ASN A 1 91 ? 38.615 62.798 12.666 1.00 7.52 ? 91 ASN A N 1 ATOM 517 C CA . ASN A 1 91 ? 39.380 64.064 12.629 1.00 8.01 ? 91 ASN A CA 1 ATOM 518 C C . ASN A 1 91 ? 39.537 64.547 11.197 1.00 8.60 ? 91 ASN A C 1 ATOM 519 O O . ASN A 1 91 ? 40.388 64.037 10.440 1.00 10.93 ? 91 ASN A O 1 ATOM 520 C CB . ASN A 1 91 ? 40.787 63.831 13.234 1.00 8.15 ? 91 ASN A CB 1 ATOM 521 C CG . ASN A 1 91 ? 40.763 63.715 14.739 1.00 8.00 ? 91 ASN A CG 1 ATOM 522 O OD1 . ASN A 1 91 ? 40.141 62.781 15.284 1.00 10.43 ? 91 ASN A OD1 1 ATOM 523 N ND2 . ASN A 1 91 ? 41.416 64.608 15.405 1.00 6.78 ? 91 ASN A ND2 1 ATOM 524 N N . ASP A 1 92 ? 38.730 65.511 10.820 1.00 7.42 ? 92 ASP A N 1 ATOM 525 C CA . ASP A 1 92 ? 38.812 66.035 9.457 1.00 7.43 ? 92 ASP A CA 1 ATOM 526 C C . ASP A 1 92 ? 40.067 66.858 9.249 1.00 7.04 ? 92 ASP A C 1 ATOM 527 O O . ASP A 1 92 ? 40.301 67.809 10.002 1.00 8.15 ? 92 ASP A O 1 ATOM 528 C CB . ASP A 1 92 ? 37.620 66.952 9.230 1.00 7.82 ? 92 ASP A CB 1 ATOM 529 C CG . ASP A 1 92 ? 36.319 66.213 9.244 1.00 8.05 ? 92 ASP A CG 1 ATOM 530 O OD1 . ASP A 1 92 ? 36.158 65.257 8.449 1.00 7.79 ? 92 ASP A OD1 1 ATOM 531 O OD2 . ASP A 1 92 ? 35.447 66.562 10.080 1.00 9.31 ? 92 ASP A OD2 1 ATOM 532 N N . PRO A 1 93 ? 40.904 66.524 8.248 1.00 7.27 ? 93 PRO A N 1 ATOM 533 C CA . PRO A 1 93 ? 42.145 67.312 7.951 1.00 7.25 ? 93 PRO A CA 1 ATOM 534 C C . PRO A 1 93 ? 41.736 68.597 7.172 1.00 7.83 ? 93 PRO A C 1 ATOM 535 O O . PRO A 1 93 ? 42.062 68.773 5.967 1.00 9.40 ? 93 PRO A O 1 ATOM 536 C CB . PRO A 1 93 ? 43.002 66.349 7.116 1.00 8.57 ? 93 PRO A CB 1 ATOM 537 C CG . PRO A 1 93 ? 42.424 64.953 7.402 1.00 9.00 ? 93 PRO A CG 1 ATOM 538 C CD . PRO A 1 93 ? 40.893 65.251 7.504 1.00 7.43 ? 93 PRO A CD 1 ATOM 539 N N . GLY A 1 94 ? 41.017 69.484 7.885 1.00 8.41 ? 94 GLY A N 1 ATOM 540 C CA . GLY A 1 94 ? 40.469 70.720 7.338 1.00 7.83 ? 94 GLY A CA 1 ATOM 541 C C . GLY A 1 94 ? 38.974 70.527 7.091 1.00 8.46 ? 94 GLY A C 1 ATOM 542 O O . GLY A 1 94 ? 38.549 69.460 6.559 1.00 9.20 ? 94 GLY A O 1 ATOM 543 N N . TRP A 1 95 ? 38.176 71.507 7.498 1.00 7.92 ? 95 TRP A N 1 ATOM 544 C CA . TRP A 1 95 ? 36.722 71.523 7.218 1.00 7.61 ? 95 TRP A CA 1 ATOM 545 C C . TRP A 1 95 ? 36.206 72.905 7.660 1.00 7.96 ? 95 TRP A C 1 ATOM 546 O O . TRP A 1 95 ? 36.190 73.828 6.848 1.00 9.29 ? 95 TRP A O 1 ATOM 547 C CB . TRP A 1 95 ? 35.984 70.354 7.920 1.00 7.08 ? 95 TRP A CB 1 ATOM 548 C CG . TRP A 1 95 ? 34.495 70.483 7.606 1.00 7.31 ? 95 TRP A CG 1 ATOM 549 C CD1 . TRP A 1 95 ? 33.917 70.887 6.414 1.00 7.42 ? 95 TRP A CD1 1 ATOM 550 C CD2 . TRP A 1 95 ? 33.400 70.131 8.466 1.00 7.65 ? 95 TRP A CD2 1 ATOM 551 N NE1 . TRP A 1 95 ? 32.539 70.805 6.488 1.00 8.16 ? 95 TRP A NE1 1 ATOM 552 C CE2 . TRP A 1 95 ? 32.201 70.332 7.726 1.00 8.03 ? 95 TRP A CE2 1 ATOM 553 C CE3 . TRP A 1 95 ? 33.323 69.651 9.798 1.00 8.72 ? 95 TRP A CE3 1 ATOM 554 C CZ2 . TRP A 1 95 ? 30.909 70.044 8.264 1.00 8.87 ? 95 TRP A CZ2 1 ATOM 555 C CZ3 . TRP A 1 95 ? 32.033 69.370 10.332 1.00 9.71 ? 95 TRP A CZ3 1 ATOM 556 C CH2 . TRP A 1 95 ? 30.856 69.567 9.552 1.00 10.47 ? 95 TRP A CH2 1 ATOM 557 N N . ILE A 1 96 ? 35.891 73.056 8.944 1.00 8.70 ? 96 ILE A N 1 ATOM 558 C CA . ILE A 1 96 ? 35.467 74.329 9.538 1.00 11.01 ? 96 ILE A CA 1 ATOM 559 C C . ILE A 1 96 ? 36.701 75.114 10.012 1.00 9.39 ? 96 ILE A C 1 ATOM 560 O O . ILE A 1 96 ? 36.603 76.313 10.250 1.00 12.23 ? 96 ILE A O 1 ATOM 561 C CB . ILE A 1 96 ? 34.580 74.115 10.799 1.00 15.19 ? 96 ILE A CB 1 ATOM 562 C CG1 . ILE A 1 96 ? 33.384 73.303 10.455 1.00 19.20 ? 96 ILE A CG1 1 ATOM 563 C CG2 . ILE A 1 96 ? 34.126 75.449 11.401 1.00 18.72 ? 96 ILE A CG2 1 ATOM 564 C CD1 . ILE A 1 96 ? 32.828 73.787 9.205 1.00 16.36 ? 96 ILE A CD1 1 ATOM 565 N N . GLN A 1 97 ? 37.808 74.414 10.204 1.00 8.39 ? 97 GLN A N 1 ATOM 566 C CA . GLN A 1 97 ? 39.100 74.998 10.586 1.00 8.03 ? 97 GLN A CA 1 ATOM 567 C C . GLN A 1 97 ? 40.143 74.410 9.629 1.00 8.16 ? 97 GLN A C 1 ATOM 568 O O . GLN A 1 97 ? 39.902 73.386 8.985 1.00 8.28 ? 97 GLN A O 1 ATOM 569 C CB A GLN A 1 97 ? 39.458 74.596 12.021 0.50 9.50 ? 97 GLN A CB 1 ATOM 570 C CB B GLN A 1 97 ? 39.520 74.809 12.033 0.50 10.64 ? 97 GLN A CB 1 ATOM 571 C CG . GLN A 1 97 ? 38.565 75.257 13.081 1.00 10.91 ? 97 GLN A CG 1 ATOM 572 C CD A GLN A 1 97 ? 38.883 76.727 13.242 0.50 10.21 ? 97 GLN A CD 1 ATOM 573 C CD B GLN A 1 97 ? 39.017 74.987 14.545 0.50 15.73 ? 97 GLN A CD 1 ATOM 574 O OE1 A GLN A 1 97 ? 39.746 77.104 14.032 0.50 13.01 ? 97 GLN A OE1 1 ATOM 575 O OE1 B GLN A 1 97 ? 38.330 74.358 15.355 0.50 17.09 ? 97 GLN A OE1 1 ATOM 576 N NE2 A GLN A 1 97 ? 38.211 77.562 12.473 0.50 11.72 ? 97 GLN A NE2 1 ATOM 577 N NE2 B GLN A 1 97 ? 40.210 75.477 14.856 0.50 17.02 ? 97 GLN A NE2 1 ATOM 578 N N . THR A 1 98 ? 41.286 75.056 9.511 1.00 8.08 ? 98 THR A N 1 ATOM 579 C CA . THR A 1 98 ? 42.329 74.487 8.652 1.00 8.09 ? 98 THR A CA 1 ATOM 580 C C . THR A 1 98 ? 42.938 73.275 9.372 1.00 7.94 ? 98 THR A C 1 ATOM 581 O O . THR A 1 98 ? 42.704 73.043 10.574 1.00 8.31 ? 98 THR A O 1 ATOM 582 C CB . THR A 1 98 ? 43.460 75.456 8.423 1.00 7.55 ? 98 THR A CB 1 ATOM 583 O OG1 . THR A 1 98 ? 44.058 75.744 9.678 1.00 9.05 ? 98 THR A OG1 1 ATOM 584 C CG2 . THR A 1 98 ? 42.982 76.725 7.775 1.00 9.42 ? 98 THR A CG2 1 ATOM 585 N N . PHE A 1 99 ? 43.690 72.460 8.637 1.00 8.18 ? 99 PHE A N 1 ATOM 586 C CA . PHE A 1 99 ? 44.413 71.356 9.230 1.00 7.84 ? 99 PHE A CA 1 ATOM 587 C C . PHE A 1 99 ? 45.229 71.820 10.446 1.00 7.73 ? 99 PHE A C 1 ATOM 588 O O . PHE A 1 99 ? 45.148 71.216 11.514 1.00 8.46 ? 99 PHE A O 1 ATOM 589 C CB . PHE A 1 99 ? 45.383 70.789 8.170 1.00 8.25 ? 99 PHE A CB 1 ATOM 590 C CG . PHE A 1 99 ? 46.274 69.693 8.681 1.00 7.97 ? 99 PHE A CG 1 ATOM 591 C CD1 . PHE A 1 99 ? 47.505 69.978 9.274 1.00 8.93 ? 99 PHE A CD1 1 ATOM 592 C CD2 . PHE A 1 99 ? 45.879 68.355 8.598 1.00 9.07 ? 99 PHE A CD2 1 ATOM 593 C CE1 . PHE A 1 99 ? 48.321 68.942 9.768 1.00 10.36 ? 99 PHE A CE1 1 ATOM 594 C CE2 . PHE A 1 99 ? 46.685 67.307 9.090 1.00 8.73 ? 99 PHE A CE2 1 ATOM 595 C CZ . PHE A 1 99 ? 47.908 67.605 9.673 1.00 8.87 ? 99 PHE A CZ 1 ATOM 596 N N . GLU A 1 100 ? 45.996 72.910 10.311 1.00 8.18 ? 100 GLU A N 1 ATOM 597 C CA . GLU A 1 100 ? 46.838 73.313 11.432 1.00 8.00 ? 100 GLU A CA 1 ATOM 598 C C . GLU A 1 100 ? 46.015 73.860 12.584 1.00 7.96 ? 100 GLU A C 1 ATOM 599 O O . GLU A 1 100 ? 46.403 73.601 13.742 1.00 8.72 ? 100 GLU A O 1 ATOM 600 C CB . GLU A 1 100 ? 47.851 74.336 10.930 1.00 9.54 ? 100 GLU A CB 1 ATOM 601 C CG . GLU A 1 100 ? 48.904 74.715 11.993 1.00 10.70 ? 100 GLU A CG 1 ATOM 602 C CD . GLU A 1 100 ? 49.776 73.568 12.448 1.00 11.86 ? 100 GLU A CD 1 ATOM 603 O OE1 . GLU A 1 100 ? 49.977 72.530 11.796 1.00 12.13 ? 100 GLU A OE1 1 ATOM 604 O OE2 . GLU A 1 100 ? 50.415 73.752 13.533 1.00 13.84 ? 100 GLU A OE2 1 ATOM 605 N N . GLU A 1 101 ? 44.929 74.574 12.296 1.00 8.53 ? 101 GLU A N 1 ATOM 606 C CA . GLU A 1 101 ? 44.075 75.066 13.394 1.00 9.29 ? 101 GLU A CA 1 ATOM 607 C C . GLU A 1 101 ? 43.457 73.904 14.170 1.00 8.95 ? 101 GLU A C 1 ATOM 608 O O . GLU A 1 101 ? 43.452 73.911 15.423 1.00 9.27 ? 101 GLU A O 1 ATOM 609 C CB . GLU A 1 101 ? 42.962 75.901 12.830 1.00 10.13 ? 101 GLU A CB 1 ATOM 610 C CG . GLU A 1 101 ? 43.393 77.291 12.398 1.00 13.40 ? 101 GLU A CG 1 ATOM 611 C CD . GLU A 1 101 ? 42.311 78.045 11.576 1.00 14.44 ? 101 GLU A CD 1 ATOM 612 O OE1 . GLU A 1 101 ? 41.359 77.508 10.978 1.00 12.29 ? 101 GLU A OE1 1 ATOM 613 O OE2 . GLU A 1 101 ? 42.418 79.287 11.477 1.00 19.19 ? 101 GLU A OE2 1 ATOM 614 N N . TYR A 1 102 ? 42.925 72.904 13.473 1.00 8.50 ? 102 TYR A N 1 ATOM 615 C CA . TYR A 1 102 ? 42.408 71.745 14.194 1.00 8.72 ? 102 TYR A CA 1 ATOM 616 C C . TYR A 1 102 ? 43.524 71.014 14.929 1.00 8.81 ? 102 TYR A C 1 ATOM 617 O O . TYR A 1 102 ? 43.283 70.482 16.040 1.00 8.71 ? 102 TYR A O 1 ATOM 618 C CB . TYR A 1 102 ? 41.784 70.705 13.231 1.00 9.09 ? 102 TYR A CB 1 ATOM 619 C CG . TYR A 1 102 ? 40.383 70.977 12.758 1.00 8.39 ? 102 TYR A CG 1 ATOM 620 C CD1 . TYR A 1 102 ? 39.318 71.200 13.645 1.00 8.61 ? 102 TYR A CD1 1 ATOM 621 C CD2 . TYR A 1 102 ? 40.085 70.842 11.394 1.00 8.21 ? 102 TYR A CD2 1 ATOM 622 C CE1 . TYR A 1 102 ? 37.984 71.293 13.159 1.00 8.76 ? 102 TYR A CE1 1 ATOM 623 C CE2 . TYR A 1 102 ? 38.792 70.878 10.907 1.00 7.99 ? 102 TYR A CE2 1 ATOM 624 C CZ . TYR A 1 102 ? 37.742 71.108 11.792 1.00 8.18 ? 102 TYR A CZ 1 ATOM 625 O OH . TYR A 1 102 ? 36.448 71.147 11.278 1.00 9.53 ? 102 TYR A OH 1 ATOM 626 N N . TYR A 1 103 ? 44.699 70.883 14.340 1.00 8.68 ? 103 TYR A N 1 ATOM 627 C CA . TYR A 1 103 ? 45.745 70.200 15.044 1.00 8.68 ? 103 TYR A CA 1 ATOM 628 C C . TYR A 1 103 ? 46.061 70.884 16.380 1.00 9.29 ? 103 TYR A C 1 ATOM 629 O O . TYR A 1 103 ? 46.229 70.215 17.385 1.00 9.79 ? 103 TYR A O 1 ATOM 630 C CB . TYR A 1 103 ? 47.017 70.150 14.202 1.00 9.06 ? 103 TYR A CB 1 ATOM 631 C CG . TYR A 1 103 ? 48.163 69.527 14.915 1.00 9.80 ? 103 TYR A CG 1 ATOM 632 C CD1 . TYR A 1 103 ? 48.198 68.155 15.213 1.00 10.03 ? 103 TYR A CD1 1 ATOM 633 C CD2 . TYR A 1 103 ? 49.215 70.339 15.385 1.00 10.29 ? 103 TYR A CD2 1 ATOM 634 C CE1 . TYR A 1 103 ? 49.203 67.604 15.945 1.00 10.27 ? 103 TYR A CE1 1 ATOM 635 C CE2 . TYR A 1 103 ? 50.236 69.783 16.138 1.00 10.82 ? 103 TYR A CE2 1 ATOM 636 C CZ . TYR A 1 103 ? 50.234 68.422 16.419 1.00 10.53 ? 103 TYR A CZ 1 ATOM 637 O OH . TYR A 1 103 ? 51.232 67.851 17.243 1.00 12.33 ? 103 TYR A OH 1 ATOM 638 N N . GLN A 1 104 ? 46.169 72.206 16.353 1.00 9.50 ? 104 GLN A N 1 ATOM 639 C CA . GLN A 1 104 ? 46.520 72.942 17.573 1.00 10.31 ? 104 GLN A CA 1 ATOM 640 C C . GLN A 1 104 ? 45.423 72.968 18.580 1.00 10.86 ? 104 GLN A C 1 ATOM 641 O O . GLN A 1 104 ? 45.708 72.861 19.787 1.00 12.25 ? 104 GLN A O 1 ATOM 642 C CB . GLN A 1 104 ? 46.869 74.402 17.229 1.00 10.58 ? 104 GLN A CB 1 ATOM 643 C CG . GLN A 1 104 ? 48.193 74.552 16.461 1.00 11.45 ? 104 GLN A CG 1 ATOM 644 C CD . GLN A 1 104 ? 49.380 74.050 17.241 1.00 11.87 ? 104 GLN A CD 1 ATOM 645 O OE1 . GLN A 1 104 ? 49.409 74.150 18.490 1.00 13.34 ? 104 GLN A OE1 1 ATOM 646 N NE2 . GLN A 1 104 ? 50.389 73.531 16.528 1.00 13.01 ? 104 GLN A NE2 1 ATOM 647 N N . HIS A 1 105 ? 44.176 73.078 18.154 1.00 10.67 ? 105 HIS A N 1 ATOM 648 C CA . HIS A 1 105 ? 43.096 73.201 19.134 1.00 11.65 ? 105 HIS A CA 1 ATOM 649 C C A HIS A 1 105 ? 42.583 71.864 19.620 0.50 11.45 ? 105 HIS A C 1 ATOM 650 C C B HIS A 1 105 ? 42.418 71.938 19.527 0.50 11.63 ? 105 HIS A C 1 ATOM 651 O O A HIS A 1 105 ? 42.252 71.703 20.797 0.50 11.34 ? 105 HIS A O 1 ATOM 652 O O B HIS A 1 105 ? 41.785 71.904 20.577 0.50 11.67 ? 105 HIS A O 1 ATOM 653 C CB . HIS A 1 105 ? 41.919 73.969 18.522 1.00 14.54 ? 105 HIS A CB 1 ATOM 654 C CG A HIS A 1 105 ? 42.291 75.310 17.953 0.50 17.78 ? 105 HIS A CG 1 ATOM 655 C CG B HIS A 1 105 ? 40.937 74.518 19.548 0.50 16.28 ? 105 HIS A CG 1 ATOM 656 N ND1 A HIS A 1 105 ? 41.606 75.893 16.907 0.50 19.96 ? 105 HIS A ND1 1 ATOM 657 N ND1 B HIS A 1 105 ? 39.860 73.727 19.884 0.50 17.40 ? 105 HIS A ND1 1 ATOM 658 C CD2 A HIS A 1 105 ? 43.273 76.178 18.288 0.50 19.59 ? 105 HIS A CD2 1 ATOM 659 C CD2 B HIS A 1 105 ? 40.857 75.617 20.335 0.50 18.50 ? 105 HIS A CD2 1 ATOM 660 C CE1 A HIS A 1 105 ? 42.155 77.061 16.621 0.50 20.75 ? 105 HIS A CE1 1 ATOM 661 C CE1 B HIS A 1 105 ? 39.161 74.321 20.836 0.50 18.68 ? 105 HIS A CE1 1 ATOM 662 N NE2 A HIS A 1 105 ? 43.168 77.257 17.443 0.50 20.57 ? 105 HIS A NE2 1 ATOM 663 N NE2 B HIS A 1 105 ? 39.746 75.469 21.128 0.50 19.03 ? 105 HIS A NE2 1 ATOM 664 N N . ASP A 1 106 ? 42.565 70.882 18.716 1.00 11.06 ? 106 ASP A N 1 ATOM 665 C CA . ASP A 1 106 ? 41.969 69.603 19.045 1.00 10.95 ? 106 ASP A CA 1 ATOM 666 C C . ASP A 1 106 ? 42.786 68.354 18.905 1.00 9.71 ? 106 ASP A C 1 ATOM 667 O O . ASP A 1 106 ? 43.028 67.630 19.898 1.00 10.09 ? 106 ASP A O 1 ATOM 668 C CB . ASP A 1 106 ? 40.668 69.412 18.219 1.00 13.09 ? 106 ASP A CB 1 ATOM 669 C CG . ASP A 1 106 ? 39.668 70.476 18.543 1.00 15.78 ? 106 ASP A CG 1 ATOM 670 O OD1 . ASP A 1 106 ? 38.928 70.300 19.524 1.00 16.95 ? 106 ASP A OD1 1 ATOM 671 O OD2 . ASP A 1 106 ? 39.654 71.501 17.842 1.00 19.73 ? 106 ASP A OD2 1 ATOM 672 N N . THR A 1 107 ? 43.295 68.094 17.707 1.00 9.65 ? 107 THR A N 1 ATOM 673 C CA . THR A 1 107 ? 43.915 66.814 17.464 1.00 8.30 ? 107 THR A CA 1 ATOM 674 C C . THR A 1 107 ? 45.172 66.537 18.274 1.00 8.60 ? 107 THR A C 1 ATOM 675 O O . THR A 1 107 ? 45.408 65.402 18.693 1.00 8.85 ? 107 THR A O 1 ATOM 676 C CB . THR A 1 107 ? 44.171 66.653 15.949 1.00 8.04 ? 107 THR A CB 1 ATOM 677 O OG1 . THR A 1 107 ? 42.943 66.908 15.276 1.00 8.65 ? 107 THR A OG1 1 ATOM 678 C CG2 . THR A 1 107 ? 44.667 65.222 15.624 1.00 9.15 ? 107 THR A CG2 1 ATOM 679 N N . LYS A 1 108 ? 45.981 67.577 18.538 1.00 9.09 ? 108 LYS A N 1 ATOM 680 C CA . LYS A 1 108 ? 47.178 67.253 19.317 1.00 9.14 ? 108 LYS A CA 1 ATOM 681 C C . LYS A 1 108 ? 46.818 66.811 20.735 1.00 8.66 ? 108 LYS A C 1 ATOM 682 O O . LYS A 1 108 ? 47.541 66.009 21.278 1.00 10.11 ? 108 LYS A O 1 ATOM 683 C CB . LYS A 1 108 ? 48.177 68.452 19.308 1.00 10.85 ? 108 LYS A CB 1 ATOM 684 C CG . LYS A 1 108 ? 47.866 69.594 20.219 1.00 12.39 ? 108 LYS A CG 1 ATOM 685 C CD . LYS A 1 108 ? 48.989 70.641 20.020 1.00 14.21 ? 108 LYS A CD 1 ATOM 686 C CE . LYS A 1 108 ? 48.836 71.720 21.031 1.00 15.48 ? 108 LYS A CE 1 ATOM 687 N NZ . LYS A 1 108 ? 49.979 72.698 20.893 1.00 17.27 ? 108 LYS A NZ 1 ATOM 688 N N . HIS A 1 109 ? 45.714 67.325 21.258 1.00 8.79 ? 109 HIS A N 1 ATOM 689 C CA . HIS A 1 109 ? 45.271 66.949 22.602 1.00 9.50 ? 109 HIS A CA 1 ATOM 690 C C . HIS A 1 109 ? 44.650 65.586 22.581 1.00 10.01 ? 109 HIS A C 1 ATOM 691 O O . HIS A 1 109 ? 44.871 64.774 23.498 1.00 10.21 ? 109 HIS A O 1 ATOM 692 C CB . HIS A 1 109 ? 44.292 67.997 23.110 1.00 12.17 ? 109 HIS A CB 1 ATOM 693 C CG . HIS A 1 109 ? 44.893 69.353 23.150 1.00 13.93 ? 109 HIS A CG 1 ATOM 694 N ND1 . HIS A 1 109 ? 45.917 69.663 24.023 1.00 17.03 ? 109 HIS A ND1 1 ATOM 695 C CD2 . HIS A 1 109 ? 44.666 70.456 22.406 1.00 16.17 ? 109 HIS A CD2 1 ATOM 696 C CE1 . HIS A 1 109 ? 46.295 70.914 23.811 1.00 16.47 ? 109 HIS A CE1 1 ATOM 697 N NE2 . HIS A 1 109 ? 45.551 71.415 22.840 1.00 18.25 ? 109 HIS A NE2 1 ATOM 698 N N . ILE A 1 110 ? 43.879 65.283 21.530 1.00 9.74 ? 110 ILE A N 1 ATOM 699 C CA . ILE A 1 110 ? 43.285 63.947 21.420 1.00 8.96 ? 110 ILE A CA 1 ATOM 700 C C . ILE A 1 110 ? 44.380 62.893 21.396 1.00 8.87 ? 110 ILE A C 1 ATOM 701 O O . ILE A 1 110 ? 44.335 61.883 22.120 1.00 10.05 ? 110 ILE A O 1 ATOM 702 C CB . ILE A 1 110 ? 42.447 63.860 20.105 1.00 9.02 ? 110 ILE A CB 1 ATOM 703 C CG1 . ILE A 1 110 ? 41.234 64.763 20.189 1.00 9.03 ? 110 ILE A CG1 1 ATOM 704 C CG2 . ILE A 1 110 ? 42.081 62.384 19.773 1.00 9.42 ? 110 ILE A CG2 1 ATOM 705 C CD1 . ILE A 1 110 ? 40.546 64.986 18.801 1.00 9.06 ? 110 ILE A CD1 1 ATOM 706 N N . LEU A 1 111 ? 45.412 63.092 20.581 1.00 9.10 ? 111 LEU A N 1 ATOM 707 C CA . LEU A 1 111 ? 46.474 62.112 20.516 1.00 9.13 ? 111 LEU A CA 1 ATOM 708 C C . LEU A 1 111 ? 47.348 62.021 21.763 1.00 9.20 ? 111 LEU A C 1 ATOM 709 O O . LEU A 1 111 ? 47.761 60.933 22.167 1.00 10.31 ? 111 LEU A O 1 ATOM 710 C CB . LEU A 1 111 ? 47.323 62.369 19.236 1.00 8.88 ? 111 LEU A CB 1 ATOM 711 C CG . LEU A 1 111 ? 46.565 62.004 17.946 1.00 8.80 ? 111 LEU A CG 1 ATOM 712 C CD1 . LEU A 1 111 ? 47.379 62.499 16.768 1.00 10.57 ? 111 LEU A CD1 1 ATOM 713 C CD2 . LEU A 1 111 ? 46.309 60.517 17.883 1.00 11.26 ? 111 LEU A CD2 1 ATOM 714 N N . SER A 1 112 ? 47.634 63.170 22.362 1.00 9.72 ? 112 SER A N 1 ATOM 715 C CA . SER A 1 112 ? 48.465 63.138 23.564 1.00 9.90 ? 112 SER A CA 1 ATOM 716 C C . SER A 1 112 ? 47.673 62.464 24.706 1.00 10.02 ? 112 SER A C 1 ATOM 717 O O . SER A 1 112 ? 48.249 61.684 25.495 1.00 11.08 ? 112 SER A O 1 ATOM 718 C CB A SER A 1 112 ? 48.860 64.559 23.914 0.50 9.44 ? 112 SER A CB 1 ATOM 719 C CB B SER A 1 112 ? 48.510 64.670 24.056 0.50 11.80 ? 112 SER A CB 1 ATOM 720 O OG A SER A 1 112 ? 49.546 64.589 25.146 0.50 10.86 ? 112 SER A OG 1 ATOM 721 O OG B SER A 1 112 ? 49.354 65.377 23.211 0.50 16.45 ? 112 SER A OG 1 ATOM 722 N N . ASN A 1 113 ? 46.369 62.739 24.789 1.00 9.82 ? 113 ASN A N 1 ATOM 723 C CA . ASN A 1 113 ? 45.583 62.100 25.844 1.00 11.15 ? 113 ASN A CA 1 ATOM 724 C C . ASN A 1 113 ? 45.327 60.641 25.515 1.00 11.65 ? 113 ASN A C 1 ATOM 725 O O . ASN A 1 113 ? 45.241 59.803 26.445 1.00 12.19 ? 113 ASN A O 1 ATOM 726 C CB . ASN A 1 113 ? 44.342 62.896 26.176 1.00 12.50 ? 113 ASN A CB 1 ATOM 727 C CG . ASN A 1 113 ? 44.728 64.250 26.845 1.00 11.84 ? 113 ASN A CG 1 ATOM 728 O OD1 . ASN A 1 113 ? 45.856 64.371 27.437 1.00 16.82 ? 113 ASN A OD1 1 ATOM 729 N ND2 . ASN A 1 113 ? 43.886 65.242 26.722 1.00 14.17 ? 113 ASN A ND2 1 ATOM 730 N N . ALA A 1 114 ? 45.228 60.278 24.229 1.00 10.79 ? 114 ALA A N 1 ATOM 731 C CA . ALA A 1 114 ? 45.084 58.866 23.898 1.00 11.95 ? 114 ALA A CA 1 ATOM 732 C C . ALA A 1 114 ? 46.322 58.099 24.343 1.00 10.83 ? 114 ALA A C 1 ATOM 733 O O . ALA A 1 114 ? 46.252 56.962 24.882 1.00 11.54 ? 114 ALA A O 1 ATOM 734 C CB . ALA A 1 114 ? 44.926 58.726 22.374 1.00 11.80 ? 114 ALA A CB 1 ATOM 735 N N . LEU A 1 115 ? 47.496 58.696 24.152 1.00 10.98 ? 115 LEU A N 1 ATOM 736 C CA . LEU A 1 115 ? 48.727 58.033 24.546 1.00 11.06 ? 115 LEU A CA 1 ATOM 737 C C . LEU A 1 115 ? 48.736 57.770 26.068 1.00 11.96 ? 115 LEU A C 1 ATOM 738 O O . LEU A 1 115 ? 49.003 56.649 26.509 1.00 13.27 ? 115 LEU A O 1 ATOM 739 C CB . LEU A 1 115 ? 49.935 58.869 24.103 1.00 11.96 ? 115 LEU A CB 1 ATOM 740 C CG . LEU A 1 115 ? 51.296 58.321 24.554 1.00 12.89 ? 115 LEU A CG 1 ATOM 741 C CD1 . LEU A 1 115 ? 51.571 56.875 24.104 1.00 15.49 ? 115 LEU A CD1 1 ATOM 742 C CD2 . LEU A 1 115 ? 52.350 59.260 23.964 1.00 15.85 ? 115 LEU A CD2 1 ATOM 743 N N . ARG A 1 116 ? 48.365 58.800 26.804 1.00 12.51 ? 116 ARG A N 1 ATOM 744 C CA . ARG A 1 116 ? 48.345 58.663 28.255 1.00 13.70 ? 116 ARG A CA 1 ATOM 745 C C . ARG A 1 116 ? 47.278 57.654 28.706 1.00 12.43 ? 116 ARG A C 1 ATOM 746 O O . ARG A 1 116 ? 47.582 56.734 29.482 1.00 13.51 ? 116 ARG A O 1 ATOM 747 C CB . ARG A 1 116 ? 48.078 60.007 28.882 1.00 16.36 ? 116 ARG A CB 1 ATOM 748 C CG . ARG A 1 116 ? 47.713 59.942 30.406 1.00 20.91 ? 116 ARG A CG 1 ATOM 749 C CD . ARG A 1 116 ? 46.876 61.182 30.814 1.00 24.94 ? 116 ARG A CD 1 ATOM 750 N NE . ARG A 1 116 ? 46.443 61.167 32.218 1.00 27.81 ? 116 ARG A NE 1 ATOM 751 C CZ . ARG A 1 116 ? 46.096 62.262 32.895 1.00 29.94 ? 116 ARG A CZ 1 ATOM 752 N NH1 . ARG A 1 116 ? 46.138 63.451 32.304 1.00 29.84 ? 116 ARG A NH1 1 ATOM 753 N NH2 . ARG A 1 116 ? 45.701 62.165 34.169 1.00 31.53 ? 116 ARG A NH2 1 ATOM 754 N N . HIS A 1 117 ? 46.048 57.813 28.231 1.00 12.38 ? 117 HIS A N 1 ATOM 755 C CA . HIS A 1 117 ? 44.990 56.917 28.694 1.00 12.75 ? 117 HIS A CA 1 ATOM 756 C C . HIS A 1 117 ? 45.146 55.510 28.275 1.00 13.07 ? 117 HIS A C 1 ATOM 757 O O . HIS A 1 117 ? 44.850 54.612 29.062 1.00 13.41 ? 117 HIS A O 1 ATOM 758 C CB . HIS A 1 117 ? 43.631 57.464 28.346 1.00 14.01 ? 117 HIS A CB 1 ATOM 759 C CG . HIS A 1 117 ? 43.275 58.655 29.171 1.00 15.76 ? 117 HIS A CG 1 ATOM 760 N ND1 . HIS A 1 117 ? 42.639 58.544 30.399 1.00 16.29 ? 117 HIS A ND1 1 ATOM 761 C CD2 . HIS A 1 117 ? 43.580 59.965 29.013 1.00 16.96 ? 117 HIS A CD2 1 ATOM 762 C CE1 . HIS A 1 117 ? 42.578 59.745 30.959 1.00 16.41 ? 117 HIS A CE1 1 ATOM 763 N NE2 . HIS A 1 117 ? 43.145 60.621 30.145 1.00 17.48 ? 117 HIS A NE2 1 ATOM 764 N N . LEU A 1 118 ? 45.571 55.235 27.043 1.00 11.59 ? 118 LEU A N 1 ATOM 765 C CA . LEU A 1 118 ? 45.784 53.857 26.648 1.00 11.90 ? 118 LEU A CA 1 ATOM 766 C C . LEU A 1 118 ? 46.955 53.251 27.430 1.00 12.37 ? 118 LEU A C 1 ATOM 767 O O . LEU A 1 118 ? 46.886 52.101 27.885 1.00 13.08 ? 118 LEU A O 1 ATOM 768 C CB . LEU A 1 118 ? 46.012 53.804 25.105 1.00 11.35 ? 118 LEU A CB 1 ATOM 769 C CG . LEU A 1 118 ? 44.749 54.242 24.300 1.00 13.15 ? 118 LEU A CG 1 ATOM 770 C CD1 . LEU A 1 118 ? 45.213 54.406 22.794 1.00 14.12 ? 118 LEU A CD1 1 ATOM 771 C CD2 . LEU A 1 118 ? 43.626 53.229 24.425 1.00 14.05 ? 118 LEU A CD2 1 ATOM 772 N N . HIS A 1 119 ? 48.019 54.017 27.621 1.00 12.73 ? 119 HIS A N 1 ATOM 773 C CA . HIS A 1 119 ? 49.123 53.467 28.381 1.00 12.83 ? 119 HIS A CA 1 ATOM 774 C C . HIS A 1 119 ? 48.648 53.052 29.774 1.00 14.30 ? 119 HIS A C 1 ATOM 775 O O . HIS A 1 119 ? 48.978 51.976 30.245 1.00 15.08 ? 119 HIS A O 1 ATOM 776 C CB . HIS A 1 119 ? 50.207 54.525 28.534 1.00 16.71 ? 119 HIS A CB 1 ATOM 777 C CG . HIS A 1 119 ? 51.335 54.101 29.410 1.00 19.83 ? 119 HIS A CG 1 ATOM 778 N ND1 . HIS A 1 119 ? 51.406 54.448 30.742 1.00 22.81 ? 119 HIS A ND1 1 ATOM 779 C CD2 . HIS A 1 119 ? 52.402 53.306 29.161 1.00 22.25 ? 119 HIS A CD2 1 ATOM 780 C CE1 . HIS A 1 119 ? 52.478 53.881 31.278 1.00 23.27 ? 119 HIS A CE1 1 ATOM 781 N NE2 . HIS A 1 119 ? 53.096 53.185 30.341 1.00 24.01 ? 119 HIS A NE2 1 ATOM 782 N N . ASP A 1 120 ? 47.870 53.905 30.402 1.00 14.42 ? 120 ASP A N 1 ATOM 783 C CA . ASP A 1 120 ? 47.419 53.628 31.785 1.00 15.49 ? 120 ASP A CA 1 ATOM 784 C C . ASP A 1 120 ? 46.260 52.638 31.950 1.00 16.60 ? 120 ASP A C 1 ATOM 785 O O . ASP A 1 120 ? 46.010 52.180 33.083 1.00 17.05 ? 120 ASP A O 1 ATOM 786 C CB . ASP A 1 120 ? 47.006 54.937 32.461 1.00 16.16 ? 120 ASP A CB 1 ATOM 787 C CG . ASP A 1 120 ? 48.196 55.851 32.762 1.00 17.64 ? 120 ASP A CG 1 ATOM 788 O OD1 . ASP A 1 120 ? 49.360 55.410 32.673 1.00 20.78 ? 120 ASP A OD1 1 ATOM 789 O OD2 . ASP A 1 120 ? 47.982 57.026 33.084 1.00 20.60 ? 120 ASP A OD2 1 ATOM 790 N N . ASN A 1 121 ? 45.551 52.280 30.875 1.00 14.76 ? 121 ASN A N 1 ATOM 791 C CA . ASN A 1 121 ? 44.360 51.412 30.951 1.00 13.62 ? 121 ASN A CA 1 ATOM 792 C C . ASN A 1 121 ? 44.568 50.374 29.889 1.00 14.13 ? 121 ASN A C 1 ATOM 793 O O . ASN A 1 121 ? 44.084 50.518 28.767 1.00 14.07 ? 121 ASN A O 1 ATOM 794 C CB . ASN A 1 121 ? 43.115 52.234 30.701 1.00 12.95 ? 121 ASN A CB 1 ATOM 795 C CG . ASN A 1 121 ? 42.943 53.323 31.743 1.00 13.56 ? 121 ASN A CG 1 ATOM 796 O OD1 . ASN A 1 121 ? 43.320 54.503 31.543 1.00 16.29 ? 121 ASN A OD1 1 ATOM 797 N ND2 . ASN A 1 121 ? 42.386 52.925 32.890 1.00 12.83 ? 121 ASN A ND2 1 ATOM 798 N N . PRO A 1 122 ? 45.278 49.300 30.205 1.00 13.18 ? 122 PRO A N 1 ATOM 799 C CA . PRO A 1 122 ? 45.586 48.260 29.219 1.00 13.32 ? 122 PRO A CA 1 ATOM 800 C C . PRO A 1 122 ? 44.471 47.624 28.408 1.00 13.68 ? 122 PRO A C 1 ATOM 801 O O . PRO A 1 122 ? 44.768 47.113 27.280 1.00 14.67 ? 122 PRO A O 1 ATOM 802 C CB . PRO A 1 122 ? 46.397 47.221 30.019 1.00 14.21 ? 122 PRO A CB 1 ATOM 803 C CG . PRO A 1 122 ? 46.937 48.031 31.182 1.00 16.15 ? 122 PRO A CG 1 ATOM 804 C CD . PRO A 1 122 ? 45.801 48.933 31.556 1.00 14.26 ? 122 PRO A CD 1 ATOM 805 N N . GLU A 1 123 ? 43.235 47.615 28.911 1.00 13.10 ? 123 GLU A N 1 ATOM 806 C CA . GLU A 1 123 ? 42.145 47.006 28.140 1.00 14.12 ? 123 GLU A CA 1 ATOM 807 C C . GLU A 1 123 ? 41.444 48.001 27.220 1.00 13.09 ? 123 GLU A C 1 ATOM 808 O O . GLU A 1 123 ? 40.593 47.601 26.429 1.00 14.08 ? 123 GLU A O 1 ATOM 809 C CB . GLU A 1 123 ? 41.093 46.337 29.052 1.00 15.58 ? 123 GLU A CB 1 ATOM 810 C CG . GLU A 1 123 ? 41.663 45.233 29.962 1.00 21.10 ? 123 GLU A CG 1 ATOM 811 C CD . GLU A 1 123 ? 42.325 44.139 29.200 1.00 23.87 ? 123 GLU A CD 1 ATOM 812 O OE1 . GLU A 1 123 ? 41.697 43.590 28.263 1.00 26.03 ? 123 GLU A OE1 1 ATOM 813 O OE2 . GLU A 1 123 ? 43.491 43.806 29.548 1.00 28.34 ? 123 GLU A OE2 1 ATOM 814 N N . MET A 1 124 ? 41.741 49.291 27.373 1.00 12.11 ? 124 MET A N 1 ATOM 815 C CA . MET A 1 124 ? 41.108 50.312 26.540 1.00 11.85 ? 124 MET A CA 1 ATOM 816 C C . MET A 1 124 ? 41.762 50.217 25.143 1.00 10.98 ? 124 MET A C 1 ATOM 817 O O . MET A 1 124 ? 42.927 49.864 25.016 1.00 11.07 ? 124 MET A O 1 ATOM 818 C CB . MET A 1 124 ? 41.348 51.682 27.167 1.00 13.19 ? 124 MET A CB 1 ATOM 819 C CG . MET A 1 124 ? 40.631 52.862 26.484 1.00 13.75 ? 124 MET A CG 1 ATOM 820 S SD . MET A 1 124 ? 38.869 52.575 26.315 1.00 13.84 ? 124 MET A SD 1 ATOM 821 C CE . MET A 1 124 ? 38.365 54.140 25.444 1.00 14.84 ? 124 MET A CE 1 ATOM 822 N N . LYS A 1 125 ? 40.968 50.545 24.110 1.00 10.34 ? 125 LYS A N 1 ATOM 823 C CA . LYS A 1 125 ? 41.394 50.473 22.719 1.00 10.78 ? 125 LYS A CA 1 ATOM 824 C C . LYS A 1 125 ? 40.974 51.746 21.996 1.00 10.55 ? 125 LYS A C 1 ATOM 825 O O . LYS A 1 125 ? 40.101 52.498 22.450 1.00 10.83 ? 125 LYS A O 1 ATOM 826 C CB . LYS A 1 125 ? 40.690 49.316 22.015 1.00 12.82 ? 125 LYS A CB 1 ATOM 827 C CG . LYS A 1 125 ? 40.875 47.960 22.710 1.00 16.19 ? 125 LYS A CG 1 ATOM 828 C CD . LYS A 1 125 ? 42.246 47.462 22.479 1.00 19.12 ? 125 LYS A CD 1 ATOM 829 C CE . LYS A 1 125 ? 42.578 46.207 23.297 1.00 22.32 ? 125 LYS A CE 1 ATOM 830 N NZ . LYS A 1 125 ? 41.614 45.145 23.060 1.00 24.00 ? 125 LYS A NZ 1 ATOM 831 N N . PHE A 1 126 ? 41.610 51.978 20.825 1.00 9.46 ? 126 PHE A N 1 ATOM 832 C CA . PHE A 1 126 ? 41.307 53.188 20.051 1.00 8.83 ? 126 PHE A CA 1 ATOM 833 C C . PHE A 1 126 ? 41.804 52.941 18.628 1.00 7.75 ? 126 PHE A C 1 ATOM 834 O O . PHE A 1 126 ? 42.853 52.372 18.443 1.00 9.93 ? 126 PHE A O 1 ATOM 835 C CB . PHE A 1 126 ? 42.080 54.371 20.686 1.00 9.33 ? 126 PHE A CB 1 ATOM 836 C CG . PHE A 1 126 ? 41.691 55.751 20.189 1.00 8.45 ? 126 PHE A CG 1 ATOM 837 C CD1 . PHE A 1 126 ? 40.379 56.185 20.206 1.00 8.77 ? 126 PHE A CD1 1 ATOM 838 C CD2 . PHE A 1 126 ? 42.724 56.665 19.840 1.00 9.34 ? 126 PHE A CD2 1 ATOM 839 C CE1 . PHE A 1 126 ? 40.074 57.560 19.876 1.00 9.76 ? 126 PHE A CE1 1 ATOM 840 C CE2 . PHE A 1 126 ? 42.426 58.018 19.527 1.00 9.13 ? 126 PHE A CE2 1 ATOM 841 C CZ . PHE A 1 126 ? 41.124 58.474 19.541 1.00 8.81 ? 126 PHE A CZ 1 ATOM 842 N N . ILE A 1 127 ? 41.007 53.388 17.649 1.00 8.49 ? 127 ILE A N 1 ATOM 843 C CA . ILE A 1 127 ? 41.429 53.260 16.242 1.00 7.98 ? 127 ILE A CA 1 ATOM 844 C C . ILE A 1 127 ? 41.671 54.653 15.687 1.00 7.77 ? 127 ILE A C 1 ATOM 845 O O . ILE A 1 127 ? 41.077 55.653 16.123 1.00 8.18 ? 127 ILE A O 1 ATOM 846 C CB . ILE A 1 127 ? 40.408 52.524 15.335 1.00 8.45 ? 127 ILE A CB 1 ATOM 847 C CG1 . ILE A 1 127 ? 39.000 53.147 15.355 1.00 8.57 ? 127 ILE A CG1 1 ATOM 848 C CG2 . ILE A 1 127 ? 40.367 51.055 15.785 1.00 8.99 ? 127 ILE A CG2 1 ATOM 849 C CD1 . ILE A 1 127 ? 38.073 52.537 14.238 1.00 8.71 ? 127 ILE A CD1 1 ATOM 850 N N . TRP A 1 128 ? 42.624 54.717 14.775 1.00 7.83 ? 128 TRP A N 1 ATOM 851 C CA . TRP A 1 128 ? 43.015 56.007 14.152 1.00 7.33 ? 128 TRP A CA 1 ATOM 852 C C . TRP A 1 128 ? 43.135 55.889 12.648 1.00 6.54 ? 128 TRP A C 1 ATOM 853 O O . TRP A 1 128 ? 43.799 54.972 12.156 1.00 7.26 ? 128 TRP A O 1 ATOM 854 C CB . TRP A 1 128 ? 44.361 56.479 14.731 1.00 7.69 ? 128 TRP A CB 1 ATOM 855 C CG . TRP A 1 128 ? 44.647 57.931 14.393 1.00 7.33 ? 128 TRP A CG 1 ATOM 856 C CD1 . TRP A 1 128 ? 45.338 58.436 13.295 1.00 7.13 ? 128 TRP A CD1 1 ATOM 857 C CD2 . TRP A 1 128 ? 44.069 59.037 15.050 1.00 7.33 ? 128 TRP A CD2 1 ATOM 858 N NE1 . TRP A 1 128 ? 45.211 59.788 13.252 1.00 7.80 ? 128 TRP A NE1 1 ATOM 859 C CE2 . TRP A 1 128 ? 44.434 60.202 14.317 1.00 7.03 ? 128 TRP A CE2 1 ATOM 860 C CE3 . TRP A 1 128 ? 43.250 59.168 16.207 1.00 8.84 ? 128 TRP A CE3 1 ATOM 861 C CZ2 . TRP A 1 128 ? 44.028 61.478 14.687 1.00 7.68 ? 128 TRP A CZ2 1 ATOM 862 C CZ3 . TRP A 1 128 ? 42.844 60.438 16.569 1.00 9.19 ? 128 TRP A CZ3 1 ATOM 863 C CH2 . TRP A 1 128 ? 43.239 61.593 15.798 1.00 8.20 ? 128 TRP A CH2 1 ATOM 864 N N . ALA A 1 129 ? 42.536 56.841 11.928 1.00 7.34 ? 129 ALA A N 1 ATOM 865 C CA . ALA A 1 129 ? 42.507 56.772 10.462 1.00 7.18 ? 129 ALA A CA 1 ATOM 866 C C . ALA A 1 129 ? 43.397 57.755 9.711 1.00 8.41 ? 129 ALA A C 1 ATOM 867 O O . ALA A 1 129 ? 43.977 57.368 8.714 1.00 9.41 ? 129 ALA A O 1 ATOM 868 C CB . ALA A 1 129 ? 41.068 57.017 9.972 1.00 8.97 ? 129 ALA A CB 1 ATOM 869 N N . GLU A 1 130 ? 43.505 58.997 10.168 1.00 7.82 ? 130 GLU A N 1 ATOM 870 C CA . GLU A 1 130 ? 44.131 60.056 9.347 1.00 7.61 ? 130 GLU A CA 1 ATOM 871 C C . GLU A 1 130 ? 45.605 60.205 9.673 1.00 7.05 ? 130 GLU A C 1 ATOM 872 O O . GLU A 1 130 ? 46.012 60.819 10.714 1.00 7.71 ? 130 GLU A O 1 ATOM 873 C CB . GLU A 1 130 ? 43.382 61.358 9.603 1.00 8.95 ? 130 GLU A CB 1 ATOM 874 C CG . GLU A 1 130 ? 41.838 61.300 9.335 1.00 9.22 ? 130 GLU A CG 1 ATOM 875 C CD . GLU A 1 130 ? 41.020 60.892 10.534 1.00 9.42 ? 130 GLU A CD 1 ATOM 876 O OE1 . GLU A 1 130 ? 41.615 60.635 11.590 1.00 10.92 ? 130 GLU A OE1 1 ATOM 877 O OE2 . GLU A 1 130 ? 39.776 60.860 10.390 1.00 11.65 ? 130 GLU A OE2 1 ATOM 878 N N . ILE A 1 131 ? 46.452 59.668 8.806 1.00 6.30 ? 131 ILE A N 1 ATOM 879 C CA . ILE A 1 131 ? 47.898 59.686 9.101 1.00 7.24 ? 131 ILE A CA 1 ATOM 880 C C . ILE A 1 131 ? 48.519 61.055 8.954 1.00 7.61 ? 131 ILE A C 1 ATOM 881 O O . ILE A 1 131 ? 49.529 61.306 9.615 1.00 8.84 ? 131 ILE A O 1 ATOM 882 C CB . ILE A 1 131 ? 48.604 58.604 8.265 1.00 7.13 ? 131 ILE A CB 1 ATOM 883 C CG1 . ILE A 1 131 ? 47.980 57.241 8.558 1.00 7.68 ? 131 ILE A CG1 1 ATOM 884 C CG2 . ILE A 1 131 ? 50.096 58.539 8.613 1.00 8.80 ? 131 ILE A CG2 1 ATOM 885 C CD1 . ILE A 1 131 ? 47.785 56.937 10.101 1.00 10.53 ? 131 ILE A CD1 1 ATOM 886 N N . SER A 1 132 ? 47.945 61.946 8.163 1.00 7.24 ? 132 SER A N 1 ATOM 887 C CA . SER A 1 132 ? 48.460 63.321 8.088 1.00 7.50 ? 132 SER A CA 1 ATOM 888 C C . SER A 1 132 ? 48.555 63.918 9.509 1.00 7.82 ? 132 SER A C 1 ATOM 889 O O . SER A 1 132 ? 49.621 64.461 9.871 1.00 8.59 ? 132 SER A O 1 ATOM 890 C CB . SER A 1 132 ? 47.543 64.211 7.227 1.00 7.84 ? 132 SER A CB 1 ATOM 891 O OG . SER A 1 132 ? 46.185 64.112 7.664 1.00 7.70 ? 132 SER A OG 1 ATOM 892 N N . TYR A 1 133 ? 47.489 63.772 10.319 1.00 7.46 ? 133 TYR A N 1 ATOM 893 C CA . TYR A 1 133 ? 47.530 64.293 11.686 1.00 7.36 ? 133 TYR A CA 1 ATOM 894 C C . TYR A 1 133 ? 48.473 63.465 12.546 1.00 7.05 ? 133 TYR A C 1 ATOM 895 O O . TYR A 1 133 ? 49.145 64.060 13.418 1.00 8.92 ? 133 TYR A O 1 ATOM 896 C CB . TYR A 1 133 ? 46.160 64.183 12.353 1.00 7.38 ? 133 TYR A CB 1 ATOM 897 C CG . TYR A 1 133 ? 45.215 65.310 12.000 1.00 6.80 ? 133 TYR A CG 1 ATOM 898 C CD1 . TYR A 1 133 ? 45.555 66.644 12.268 1.00 8.27 ? 133 TYR A CD1 1 ATOM 899 C CD2 . TYR A 1 133 ? 43.980 65.071 11.430 1.00 7.27 ? 133 TYR A CD2 1 ATOM 900 C CE1 . TYR A 1 133 ? 44.703 67.697 11.972 1.00 7.80 ? 133 TYR A CE1 1 ATOM 901 C CE2 . TYR A 1 133 ? 43.087 66.135 11.124 1.00 7.06 ? 133 TYR A CE2 1 ATOM 902 C CZ . TYR A 1 133 ? 43.462 67.443 11.398 1.00 8.15 ? 133 TYR A CZ 1 ATOM 903 O OH . TYR A 1 133 ? 42.642 68.503 11.116 1.00 8.81 ? 133 TYR A OH 1 ATOM 904 N N . PHE A 1 134 ? 48.502 62.145 12.393 1.00 7.42 ? 134 PHE A N 1 ATOM 905 C CA . PHE A 1 134 ? 49.339 61.343 13.270 1.00 8.30 ? 134 PHE A CA 1 ATOM 906 C C . PHE A 1 134 ? 50.803 61.660 13.026 1.00 9.18 ? 134 PHE A C 1 ATOM 907 O O . PHE A 1 134 ? 51.585 61.774 14.004 1.00 9.51 ? 134 PHE A O 1 ATOM 908 C CB . PHE A 1 134 ? 49.065 59.848 13.085 1.00 8.32 ? 134 PHE A CB 1 ATOM 909 C CG . PHE A 1 134 ? 49.624 59.029 14.207 1.00 8.93 ? 134 PHE A CG 1 ATOM 910 C CD1 . PHE A 1 134 ? 48.853 58.832 15.373 1.00 9.45 ? 134 PHE A CD1 1 ATOM 911 C CD2 . PHE A 1 134 ? 50.924 58.526 14.125 1.00 10.63 ? 134 PHE A CD2 1 ATOM 912 C CE1 . PHE A 1 134 ? 49.421 58.102 16.497 1.00 11.60 ? 134 PHE A CE1 1 ATOM 913 C CE2 . PHE A 1 134 ? 51.505 57.801 15.219 1.00 11.75 ? 134 PHE A CE2 1 ATOM 914 C CZ . PHE A 1 134 ? 50.726 57.603 16.399 1.00 11.55 ? 134 PHE A CZ 1 ATOM 915 N N . ALA A 1 135 ? 51.194 61.836 11.759 1.00 9.17 ? 135 ALA A N 1 ATOM 916 C CA . ALA A 1 135 ? 52.593 62.169 11.460 1.00 9.54 ? 135 ALA A CA 1 ATOM 917 C C . ALA A 1 135 ? 52.899 63.595 11.998 1.00 10.09 ? 135 ALA A C 1 ATOM 918 O O . ALA A 1 135 ? 54.025 63.792 12.525 1.00 12.19 ? 135 ALA A O 1 ATOM 919 C CB . ALA A 1 135 ? 52.827 62.095 9.964 1.00 10.93 ? 135 ALA A CB 1 ATOM 920 N N . ARG A 1 136 ? 51.988 64.545 11.882 1.00 10.31 ? 136 ARG A N 1 ATOM 921 C CA . ARG A 1 136 ? 52.190 65.929 12.400 1.00 11.20 ? 136 ARG A CA 1 ATOM 922 C C . ARG A 1 136 ? 52.443 65.863 13.932 1.00 12.36 ? 136 ARG A C 1 ATOM 923 O O . ARG A 1 136 ? 53.307 66.572 14.466 1.00 14.50 ? 136 ARG A O 1 ATOM 924 C CB . ARG A 1 136 ? 50.958 66.784 12.085 1.00 11.73 ? 136 ARG A CB 1 ATOM 925 C CG . ARG A 1 136 ? 50.946 68.156 12.770 1.00 11.18 ? 136 ARG A CG 1 ATOM 926 C CD . ARG A 1 136 ? 51.860 69.162 12.018 1.00 13.44 ? 136 ARG A CD 1 ATOM 927 N NE . ARG A 1 136 ? 51.803 70.479 12.680 1.00 12.92 ? 136 ARG A NE 1 ATOM 928 C CZ . ARG A 1 136 ? 52.559 70.778 13.732 1.00 13.86 ? 136 ARG A CZ 1 ATOM 929 N NH1 . ARG A 1 136 ? 53.423 69.858 14.185 1.00 14.99 ? 136 ARG A NH1 1 ATOM 930 N NH2 . ARG A 1 136 ? 52.410 71.975 14.324 1.00 12.37 ? 136 ARG A NH2 1 ATOM 931 N N . PHE A 1 137 ? 51.732 64.982 14.618 1.00 11.09 ? 137 PHE A N 1 ATOM 932 C CA . PHE A 1 137 ? 51.852 64.820 16.051 1.00 11.33 ? 137 PHE A CA 1 ATOM 933 C C . PHE A 1 137 ? 53.130 64.092 16.433 1.00 11.71 ? 137 PHE A C 1 ATOM 934 O O . PHE A 1 137 ? 53.914 64.590 17.290 1.00 12.01 ? 137 PHE A O 1 ATOM 935 C CB . PHE A 1 137 ? 50.666 63.997 16.542 1.00 10.87 ? 137 PHE A CB 1 ATOM 936 C CG . PHE A 1 137 ? 50.686 63.729 18.037 1.00 11.80 ? 137 PHE A CG 1 ATOM 937 C CD1 . PHE A 1 137 ? 50.367 64.761 18.892 1.00 11.21 ? 137 PHE A CD1 1 ATOM 938 C CD2 . PHE A 1 137 ? 51.021 62.482 18.542 1.00 12.24 ? 137 PHE A CD2 1 ATOM 939 C CE1 . PHE A 1 137 ? 50.372 64.579 20.276 1.00 13.05 ? 137 PHE A CE1 1 ATOM 940 C CE2 . PHE A 1 137 ? 51.051 62.295 19.984 1.00 12.71 ? 137 PHE A CE2 1 ATOM 941 C CZ . PHE A 1 137 ? 50.720 63.351 20.794 1.00 12.61 ? 137 PHE A CZ 1 ATOM 942 N N . TYR A 1 138 ? 53.379 62.944 15.810 1.00 12.67 ? 138 TYR A N 1 ATOM 943 C CA . TYR A 1 138 ? 54.516 62.116 16.153 1.00 14.65 ? 138 TYR A CA 1 ATOM 944 C C . TYR A 1 138 ? 55.873 62.788 15.993 1.00 15.47 ? 138 TYR A C 1 ATOM 945 O O . TYR A 1 138 ? 56.780 62.590 16.832 1.00 15.64 ? 138 TYR A O 1 ATOM 946 C CB A TYR A 1 138 ? 54.447 60.804 15.354 0.50 14.37 ? 138 TYR A CB 1 ATOM 947 C CB B TYR A 1 138 ? 54.587 60.903 15.169 0.50 14.37 ? 138 TYR A CB 1 ATOM 948 C CG A TYR A 1 138 ? 55.444 59.750 15.776 0.50 14.29 ? 138 TYR A CG 1 ATOM 949 C CG B TYR A 1 138 ? 55.778 59.981 15.386 0.50 14.16 ? 138 TYR A CG 1 ATOM 950 C CD1 A TYR A 1 138 ? 55.158 58.869 16.802 0.50 13.20 ? 138 TYR A CD1 1 ATOM 951 C CD1 B TYR A 1 138 ? 55.699 58.934 16.299 0.50 14.90 ? 138 TYR A CD1 1 ATOM 952 C CD2 A TYR A 1 138 ? 56.664 59.633 15.124 0.50 13.82 ? 138 TYR A CD2 1 ATOM 953 C CD2 B TYR A 1 138 ? 56.961 60.149 14.669 0.50 14.75 ? 138 TYR A CD2 1 ATOM 954 C CE1 A TYR A 1 138 ? 56.074 57.882 17.173 0.50 14.33 ? 138 TYR A CE1 1 ATOM 955 C CE1 B TYR A 1 138 ? 56.778 58.073 16.498 0.50 14.88 ? 138 TYR A CE1 1 ATOM 956 C CE2 A TYR A 1 138 ? 57.598 58.647 15.482 0.50 13.53 ? 138 TYR A CE2 1 ATOM 957 C CE2 B TYR A 1 138 ? 58.053 59.274 14.864 0.50 15.05 ? 138 TYR A CE2 1 ATOM 958 C CZ A TYR A 1 138 ? 57.287 57.778 16.501 0.50 13.70 ? 138 TYR A CZ 1 ATOM 959 C CZ B TYR A 1 138 ? 57.937 58.256 15.779 0.50 14.71 ? 138 TYR A CZ 1 ATOM 960 O OH A TYR A 1 138 ? 58.187 56.779 16.834 0.50 14.70 ? 138 TYR A OH 1 ATOM 961 O OH B TYR A 1 138 ? 58.992 57.412 16.015 0.50 15.81 ? 138 TYR A OH 1 ATOM 962 N N . HIS A 1 139 ? 56.046 63.595 14.960 1.00 15.84 ? 139 HIS A N 1 ATOM 963 C CA . HIS A 1 139 ? 57.321 64.243 14.770 1.00 17.90 ? 139 HIS A CA 1 ATOM 964 C C . HIS A 1 139 ? 57.582 65.331 15.807 1.00 18.90 ? 139 HIS A C 1 ATOM 965 O O . HIS A 1 139 ? 58.736 65.755 15.957 1.00 20.35 ? 139 HIS A O 1 ATOM 966 C CB . HIS A 1 139 ? 57.417 64.696 13.302 1.00 18.48 ? 139 HIS A CB 1 ATOM 967 C CG . HIS A 1 139 ? 57.613 63.554 12.337 1.00 19.74 ? 139 HIS A CG 1 ATOM 968 N ND1 . HIS A 1 139 ? 58.679 62.682 12.425 1.00 21.07 ? 139 HIS A ND1 1 ATOM 969 C CD2 . HIS A 1 139 ? 56.869 63.138 11.277 1.00 19.98 ? 139 HIS A CD2 1 ATOM 970 C CE1 . HIS A 1 139 ? 58.587 61.776 11.459 1.00 21.77 ? 139 HIS A CE1 1 ATOM 971 N NE2 . HIS A 1 139 ? 57.501 62.032 10.745 1.00 20.87 ? 139 HIS A NE2 1 ATOM 972 N N . ASP A 1 140 ? 56.551 65.772 16.529 1.00 18.60 ? 140 ASP A N 1 ATOM 973 C CA . ASP A 1 140 ? 56.720 66.764 17.610 1.00 18.90 ? 140 ASP A CA 1 ATOM 974 C C . ASP A 1 140 ? 56.921 66.126 18.990 1.00 17.29 ? 140 ASP A C 1 ATOM 975 O O . ASP A 1 140 ? 57.137 66.830 19.982 1.00 18.67 ? 140 ASP A O 1 ATOM 976 C CB . ASP A 1 140 ? 55.544 67.688 17.669 1.00 19.46 ? 140 ASP A CB 1 ATOM 977 C CG . ASP A 1 140 ? 55.706 68.851 16.698 1.00 21.80 ? 140 ASP A CG 1 ATOM 978 O OD1 . ASP A 1 140 ? 56.603 68.767 15.835 1.00 23.30 ? 140 ASP A OD1 1 ATOM 979 O OD2 . ASP A 1 140 ? 54.965 69.825 16.815 1.00 22.68 ? 140 ASP A OD2 1 ATOM 980 N N . LEU A 1 141 ? 56.858 64.811 19.045 1.00 16.93 ? 141 LEU A N 1 ATOM 981 C CA . LEU A 1 141 ? 57.059 64.101 20.310 1.00 16.79 ? 141 LEU A CA 1 ATOM 982 C C . LEU A 1 141 ? 58.525 63.898 20.643 1.00 17.75 ? 141 LEU A C 1 ATOM 983 O O . LEU A 1 141 ? 59.358 63.743 19.774 1.00 18.45 ? 141 LEU A O 1 ATOM 984 C CB . LEU A 1 141 ? 56.458 62.692 20.262 1.00 16.40 ? 141 LEU A CB 1 ATOM 985 C CG . LEU A 1 141 ? 54.949 62.541 20.212 1.00 17.34 ? 141 LEU A CG 1 ATOM 986 C CD1 . LEU A 1 141 ? 54.575 61.022 20.127 1.00 17.19 ? 141 LEU A CD1 1 ATOM 987 C CD2 . LEU A 1 141 ? 54.342 63.187 21.440 1.00 17.44 ? 141 LEU A CD2 1 ATOM 988 N N . GLY A 1 142 ? 58.805 63.890 21.945 1.00 18.74 ? 142 GLY A N 1 ATOM 989 C CA . GLY A 1 142 ? 60.137 63.583 22.401 1.00 20.79 ? 142 GLY A CA 1 ATOM 990 C C . GLY A 1 142 ? 60.301 62.073 22.286 1.00 20.74 ? 142 GLY A C 1 ATOM 991 O O . GLY A 1 142 ? 59.304 61.328 22.205 1.00 20.28 ? 142 GLY A O 1 ATOM 992 N N . GLU A 1 143 ? 61.539 61.607 22.300 1.00 20.62 ? 143 GLU A N 1 ATOM 993 C CA . GLU A 1 143 ? 61.830 60.193 22.181 1.00 21.32 ? 143 GLU A CA 1 ATOM 994 C C . GLU A 1 143 ? 61.116 59.316 23.211 1.00 21.32 ? 143 GLU A C 1 ATOM 995 O O . GLU A 1 143 ? 60.655 58.206 22.891 1.00 20.93 ? 143 GLU A O 1 ATOM 996 C CB . GLU A 1 143 ? 63.342 59.964 22.280 1.00 23.74 ? 143 GLU A CB 1 ATOM 997 C CG . GLU A 1 143 ? 63.810 58.612 21.772 1.00 27.05 ? 143 GLU A CG 1 ATOM 998 C CD . GLU A 1 143 ? 63.579 58.412 20.253 1.00 29.02 ? 143 GLU A CD 1 ATOM 999 O OE1 . GLU A 1 143 ? 63.360 59.399 19.485 1.00 31.40 ? 143 GLU A OE1 1 ATOM 1000 O OE2 . GLU A 1 143 ? 63.630 57.248 19.820 1.00 31.48 ? 143 GLU A OE2 1 ATOM 1001 N N . ASN A 1 144 ? 61.007 59.772 24.445 1.00 21.17 ? 144 ASN A N 1 ATOM 1002 C CA . ASN A 1 144 ? 60.366 58.950 25.446 1.00 22.40 ? 144 ASN A CA 1 ATOM 1003 C C . ASN A 1 144 ? 58.915 58.645 25.020 1.00 20.28 ? 144 ASN A C 1 ATOM 1004 O O . ASN A 1 144 ? 58.479 57.494 25.085 1.00 19.69 ? 144 ASN A O 1 ATOM 1005 C CB . ASN A 1 144 ? 60.462 59.688 26.804 1.00 25.90 ? 144 ASN A CB 1 ATOM 1006 C CG . ASN A 1 144 ? 59.604 59.068 27.905 1.00 30.12 ? 144 ASN A CG 1 ATOM 1007 O OD1 . ASN A 1 144 ? 58.382 59.332 28.004 1.00 33.33 ? 144 ASN A OD1 1 ATOM 1008 N ND2 . ASN A 1 144 ? 60.237 58.241 28.755 1.00 32.08 ? 144 ASN A ND2 1 ATOM 1009 N N . LYS A 1 145 ? 58.211 59.673 24.557 1.00 19.54 ? 145 LYS A N 1 ATOM 1010 C CA . LYS A 1 145 ? 56.826 59.503 24.123 1.00 18.22 ? 145 LYS A CA 1 ATOM 1011 C C . LYS A 1 145 ? 56.733 58.707 22.801 1.00 17.01 ? 145 LYS A C 1 ATOM 1012 O O . LYS A 1 145 ? 55.778 57.917 22.663 1.00 16.75 ? 145 LYS A O 1 ATOM 1013 C CB . LYS A 1 145 ? 56.116 60.853 23.987 1.00 19.85 ? 145 LYS A CB 1 ATOM 1014 C CG . LYS A 1 145 ? 55.852 61.556 25.326 1.00 23.31 ? 145 LYS A CG 1 ATOM 1015 C CD . LYS A 1 145 ? 54.770 60.837 26.110 1.00 27.13 ? 145 LYS A CD 1 ATOM 1016 C CE . LYS A 1 145 ? 54.371 61.610 27.373 1.00 29.97 ? 145 LYS A CE 1 ATOM 1017 N NZ . LYS A 1 145 ? 55.451 61.573 28.401 1.00 32.19 ? 145 LYS A NZ 1 ATOM 1018 N N . LYS A 1 146 ? 57.683 58.893 21.873 1.00 16.74 ? 146 LYS A N 1 ATOM 1019 C CA . LYS A 1 146 ? 57.656 58.132 20.616 1.00 16.67 ? 146 LYS A CA 1 ATOM 1020 C C . LYS A 1 146 ? 57.724 56.653 20.973 1.00 16.65 ? 146 LYS A C 1 ATOM 1021 O O . LYS A 1 146 ? 57.018 55.822 20.400 1.00 16.78 ? 146 LYS A O 1 ATOM 1022 C CB . LYS A 1 146 ? 58.833 58.482 19.704 1.00 16.13 ? 146 LYS A CB 1 ATOM 1023 C CG . LYS A 1 146 ? 58.724 59.810 19.000 1.00 16.17 ? 146 LYS A CG 1 ATOM 1024 C CD . LYS A 1 146 ? 59.973 60.030 18.135 1.00 16.88 ? 146 LYS A CD 1 ATOM 1025 C CE A LYS A 1 146 ? 59.810 61.247 17.226 0.50 17.51 ? 146 LYS A CE 1 ATOM 1026 C CE B LYS A 1 146 ? 59.862 61.036 17.043 0.50 17.44 ? 146 LYS A CE 1 ATOM 1027 N NZ A LYS A 1 146 ? 61.066 61.566 16.501 0.50 18.49 ? 146 LYS A NZ 1 ATOM 1028 N NZ B LYS A 1 146 ? 59.851 62.415 17.579 0.50 18.43 ? 146 LYS A NZ 1 ATOM 1029 N N . LEU A 1 147 ? 58.578 56.306 21.929 1.00 17.25 ? 147 LEU A N 1 ATOM 1030 C CA . LEU A 1 147 ? 58.699 54.909 22.341 1.00 16.96 ? 147 LEU A CA 1 ATOM 1031 C C . LEU A 1 147 ? 57.408 54.405 23.034 1.00 16.40 ? 147 LEU A C 1 ATOM 1032 O O . LEU A 1 147 ? 56.981 53.272 22.782 1.00 16.26 ? 147 LEU A O 1 ATOM 1033 C CB . LEU A 1 147 ? 59.902 54.757 23.293 1.00 18.15 ? 147 LEU A CB 1 ATOM 1034 C CG . LEU A 1 147 ? 61.263 54.845 22.612 1.00 20.16 ? 147 LEU A CG 1 ATOM 1035 C CD1 . LEU A 1 147 ? 62.317 54.953 23.714 1.00 21.76 ? 147 LEU A CD1 1 ATOM 1036 C CD2 . LEU A 1 147 ? 61.552 53.597 21.766 1.00 21.28 ? 147 LEU A CD2 1 ATOM 1037 N N . GLN A 1 148 ? 56.797 55.222 23.886 1.00 15.74 ? 148 GLN A N 1 ATOM 1038 C CA . GLN A 1 148 ? 55.540 54.819 24.512 1.00 17.34 ? 148 GLN A CA 1 ATOM 1039 C C . GLN A 1 148 ? 54.469 54.593 23.413 1.00 16.41 ? 148 GLN A C 1 ATOM 1040 O O . GLN A 1 148 ? 53.700 53.659 23.489 1.00 16.64 ? 148 GLN A O 1 ATOM 1041 C CB . GLN A 1 148 ? 55.037 55.895 25.456 1.00 19.52 ? 148 GLN A CB 1 ATOM 1042 C CG . GLN A 1 148 ? 55.800 55.967 26.740 1.00 23.84 ? 148 GLN A CG 1 ATOM 1043 C CD . GLN A 1 148 ? 55.076 56.835 27.750 1.00 26.37 ? 148 GLN A CD 1 ATOM 1044 O OE1 . GLN A 1 148 ? 55.307 56.713 28.972 1.00 30.03 ? 148 GLN A OE1 1 ATOM 1045 N NE2 . GLN A 1 148 ? 54.199 57.722 27.256 1.00 27.71 ? 148 GLN A NE2 1 ATOM 1046 N N . MET A 1 149 ? 54.454 55.479 22.425 1.00 15.15 ? 149 MET A N 1 ATOM 1047 C CA . MET A 1 149 ? 53.474 55.353 21.342 1.00 14.05 ? 149 MET A CA 1 ATOM 1048 C C . MET A 1 149 ? 53.709 54.067 20.570 1.00 14.01 ? 149 MET A C 1 ATOM 1049 O O . MET A 1 149 ? 52.753 53.330 20.264 1.00 13.90 ? 149 MET A O 1 ATOM 1050 C CB . MET A 1 149 ? 53.589 56.559 20.408 1.00 14.42 ? 149 MET A CB 1 ATOM 1051 C CG . MET A 1 149 ? 52.554 56.574 19.297 1.00 14.34 ? 149 MET A CG 1 ATOM 1052 S SD . MET A 1 149 ? 50.859 56.769 19.929 1.00 15.46 ? 149 MET A SD 1 ATOM 1053 C CE . MET A 1 149 ? 50.642 58.506 20.066 1.00 18.08 ? 149 MET A CE 1 ATOM 1054 N N . LYS A 1 150 ? 54.961 53.785 20.211 1.00 14.40 ? 150 LYS A N 1 ATOM 1055 C CA . LYS A 1 150 ? 55.232 52.564 19.467 1.00 16.00 ? 150 LYS A CA 1 ATOM 1056 C C . LYS A 1 150 ? 54.773 51.344 20.255 1.00 15.54 ? 150 LYS A C 1 ATOM 1057 O O . LYS A 1 150 ? 54.284 50.362 19.657 1.00 15.83 ? 150 LYS A O 1 ATOM 1058 C CB . LYS A 1 150 ? 56.720 52.428 19.119 1.00 17.29 ? 150 LYS A CB 1 ATOM 1059 C CG . LYS A 1 150 ? 57.125 53.369 18.016 1.00 19.99 ? 150 LYS A CG 1 ATOM 1060 C CD . LYS A 1 150 ? 58.490 53.038 17.430 1.00 24.27 ? 150 LYS A CD 1 ATOM 1061 C CE . LYS A 1 150 ? 59.537 53.749 18.179 1.00 26.13 ? 150 LYS A CE 1 ATOM 1062 N NZ . LYS A 1 150 ? 60.722 53.920 17.296 1.00 28.18 ? 150 LYS A NZ 1 ATOM 1063 N N . SER A 1 151 ? 54.886 51.411 21.580 1.00 15.64 ? 151 SER A N 1 ATOM 1064 C CA . SER A 1 151 ? 54.497 50.306 22.444 1.00 16.02 ? 151 SER A CA 1 ATOM 1065 C C . SER A 1 151 ? 52.986 50.054 22.457 1.00 15.29 ? 151 SER A C 1 ATOM 1066 O O . SER A 1 151 ? 52.564 48.902 22.400 1.00 16.15 ? 151 SER A O 1 ATOM 1067 C CB . SER A 1 151 ? 55.017 50.542 23.874 1.00 16.68 ? 151 SER A CB 1 ATOM 1068 O OG A SER A 1 151 ? 54.273 51.552 24.522 0.50 17.96 ? 151 SER A OG 1 ATOM 1069 O OG B SER A 1 151 ? 54.817 49.304 24.600 0.50 17.92 ? 151 SER A OG 1 ATOM 1070 N N . ILE A 1 152 ? 52.166 51.107 22.511 1.00 14.81 ? 152 ILE A N 1 ATOM 1071 C CA . ILE A 1 152 ? 50.725 50.868 22.507 1.00 13.53 ? 152 ILE A CA 1 ATOM 1072 C C . ILE A 1 152 ? 50.216 50.453 21.111 1.00 12.60 ? 152 ILE A C 1 ATOM 1073 O O . ILE A 1 152 ? 49.114 49.905 21.011 1.00 13.43 ? 152 ILE A O 1 ATOM 1074 C CB . ILE A 1 152 ? 49.851 52.013 23.090 1.00 14.12 ? 152 ILE A CB 1 ATOM 1075 C CG1 . ILE A 1 152 ? 50.096 53.324 22.378 1.00 14.40 ? 152 ILE A CG1 1 ATOM 1076 C CG2 . ILE A 1 152 ? 50.182 52.209 24.597 1.00 15.48 ? 152 ILE A CG2 1 ATOM 1077 C CD1 . ILE A 1 152 ? 49.084 54.437 22.742 1.00 15.15 ? 152 ILE A CD1 1 ATOM 1078 N N . VAL A 1 153 ? 50.998 50.718 20.068 1.00 12.51 ? 153 VAL A N 1 ATOM 1079 C CA . VAL A 1 153 ? 50.641 50.245 18.727 1.00 13.01 ? 153 VAL A CA 1 ATOM 1080 C C . VAL A 1 153 ? 51.064 48.785 18.602 1.00 14.07 ? 153 VAL A C 1 ATOM 1081 O O . VAL A 1 153 ? 50.277 47.921 18.204 1.00 14.74 ? 153 VAL A O 1 ATOM 1082 C CB . VAL A 1 153 ? 51.305 51.128 17.660 1.00 13.22 ? 153 VAL A CB 1 ATOM 1083 C CG1 . VAL A 1 153 ? 51.117 50.471 16.266 1.00 14.60 ? 153 VAL A CG1 1 ATOM 1084 C CG2 . VAL A 1 153 ? 50.724 52.500 17.711 1.00 12.77 ? 153 VAL A CG2 1 ATOM 1085 N N . LYS A 1 154 ? 52.293 48.477 19.046 1.00 14.38 ? 154 LYS A N 1 ATOM 1086 C CA . LYS A 1 154 ? 52.750 47.103 18.972 1.00 15.97 ? 154 LYS A CA 1 ATOM 1087 C C . LYS A 1 154 ? 51.898 46.126 19.786 1.00 15.95 ? 154 LYS A C 1 ATOM 1088 O O . LYS A 1 154 ? 51.676 44.993 19.347 1.00 17.69 ? 154 LYS A O 1 ATOM 1089 C CB . LYS A 1 154 ? 54.209 47.033 19.416 1.00 17.27 ? 154 LYS A CB 1 ATOM 1090 C CG . LYS A 1 154 ? 54.829 45.674 19.123 1.00 21.94 ? 154 LYS A CG 1 ATOM 1091 C CD . LYS A 1 154 ? 56.291 45.695 19.465 1.00 25.06 ? 154 LYS A CD 1 ATOM 1092 C CE . LYS A 1 154 ? 56.884 44.278 19.341 1.00 27.60 ? 154 LYS A CE 1 ATOM 1093 N NZ . LYS A 1 154 ? 58.065 44.124 20.253 1.00 29.97 ? 154 LYS A NZ 1 ATOM 1094 N N . ASN A 1 155 ? 51.392 46.549 20.952 1.00 15.89 ? 155 ASN A N 1 ATOM 1095 C CA . ASN A 1 155 ? 50.546 45.666 21.792 1.00 15.65 ? 155 ASN A CA 1 ATOM 1096 C C A ASN A 1 155 ? 49.079 45.604 21.340 0.50 15.69 ? 155 ASN A C 1 ATOM 1097 C C B ASN A 1 155 ? 49.084 45.773 21.461 0.50 16.84 ? 155 ASN A C 1 ATOM 1098 O O A ASN A 1 155 ? 48.285 44.844 21.889 0.50 15.37 ? 155 ASN A O 1 ATOM 1099 O O B ASN A 1 155 ? 48.272 45.290 22.243 0.50 16.82 ? 155 ASN A O 1 ATOM 1100 C CB A ASN A 1 155 ? 50.626 46.038 23.305 0.50 15.73 ? 155 ASN A CB 1 ATOM 1101 C CB B ASN A 1 155 ? 51.116 45.893 23.158 0.50 19.10 ? 155 ASN A CB 1 ATOM 1102 C CG A ASN A 1 155 ? 49.823 47.289 23.696 0.50 14.87 ? 155 ASN A CG 1 ATOM 1103 C CG B ASN A 1 155 ? 52.640 45.534 23.280 0.50 20.13 ? 155 ASN A CG 1 ATOM 1104 O OD1 A ASN A 1 155 ? 49.128 47.866 22.895 0.50 14.30 ? 155 ASN A OD1 1 ATOM 1105 O OD1 B ASN A 1 155 ? 53.033 44.372 23.052 0.50 21.97 ? 155 ASN A OD1 1 ATOM 1106 N ND2 A ASN A 1 155 ? 49.922 47.693 24.969 0.50 15.11 ? 155 ASN A ND2 1 ATOM 1107 N ND2 B ASN A 1 155 ? 53.491 46.530 23.591 0.50 21.38 ? 155 ASN A ND2 1 ATOM 1108 N N . GLY A 1 156 ? 48.738 46.374 20.315 1.00 15.41 ? 156 GLY A N 1 ATOM 1109 C CA . GLY A 1 156 ? 47.350 46.395 19.819 1.00 15.13 ? 156 GLY A CA 1 ATOM 1110 C C . GLY A 1 156 ? 46.306 47.301 20.429 1.00 14.77 ? 156 GLY A C 1 ATOM 1111 O O . GLY A 1 156 ? 45.143 47.204 20.056 1.00 15.74 ? 156 GLY A O 1 ATOM 1112 N N . GLN A 1 157 ? 46.684 48.178 21.352 1.00 12.05 ? 157 GLN A N 1 ATOM 1113 C CA . GLN A 1 157 ? 45.694 49.027 21.938 1.00 10.79 ? 157 GLN A CA 1 ATOM 1114 C C . GLN A 1 157 ? 45.312 50.151 20.974 1.00 9.96 ? 157 GLN A C 1 ATOM 1115 O O . GLN A 1 157 ? 44.146 50.512 20.916 1.00 11.12 ? 157 GLN A O 1 ATOM 1116 C CB . GLN A 1 157 ? 46.230 49.646 23.224 1.00 10.60 ? 157 GLN A CB 1 ATOM 1117 C CG . GLN A 1 157 ? 46.193 48.687 24.417 1.00 11.85 ? 157 GLN A CG 1 ATOM 1118 C CD . GLN A 1 157 ? 46.498 49.482 25.677 1.00 11.70 ? 157 GLN A CD 1 ATOM 1119 O OE1 . GLN A 1 157 ? 45.631 50.158 26.250 1.00 14.56 ? 157 GLN A OE1 1 ATOM 1120 N NE2 . GLN A 1 157 ? 47.749 49.454 26.062 1.00 11.96 ? 157 GLN A NE2 1 ATOM 1121 N N . LEU A 1 158 ? 46.324 50.740 20.309 1.00 9.98 ? 158 LEU A N 1 ATOM 1122 C CA . LEU A 1 158 ? 46.067 51.801 19.325 1.00 10.18 ? 158 LEU A CA 1 ATOM 1123 C C . LEU A 1 158 ? 46.268 51.117 17.959 1.00 9.68 ? 158 LEU A C 1 ATOM 1124 O O . LEU A 1 158 ? 47.336 50.568 17.692 1.00 11.08 ? 158 LEU A O 1 ATOM 1125 C CB . LEU A 1 158 ? 47.065 52.952 19.484 1.00 11.88 ? 158 LEU A CB 1 ATOM 1126 C CG . LEU A 1 158 ? 47.010 53.996 18.374 1.00 13.46 ? 158 LEU A CG 1 ATOM 1127 C CD1 . LEU A 1 158 ? 45.718 54.642 18.424 1.00 15.34 ? 158 LEU A CD1 1 ATOM 1128 C CD2 . LEU A 1 158 ? 48.144 55.045 18.594 1.00 15.07 ? 158 LEU A CD2 1 ATOM 1129 N N . GLU A 1 159 ? 45.197 51.094 17.156 1.00 9.05 ? 159 GLU A N 1 ATOM 1130 C CA . GLU A 1 159 ? 45.272 50.434 15.846 1.00 9.01 ? 159 GLU A CA 1 ATOM 1131 C C . GLU A 1 159 ? 44.922 51.404 14.732 1.00 8.19 ? 159 GLU A C 1 ATOM 1132 O O . GLU A 1 159 ? 43.889 52.084 14.759 1.00 9.10 ? 159 GLU A O 1 ATOM 1133 C CB . GLU A 1 159 ? 44.288 49.280 15.835 1.00 9.38 ? 159 GLU A CB 1 ATOM 1134 C CG . GLU A 1 159 ? 44.234 48.538 14.501 1.00 10.02 ? 159 GLU A CG 1 ATOM 1135 C CD . GLU A 1 159 ? 43.234 47.390 14.564 1.00 12.57 ? 159 GLU A CD 1 ATOM 1136 O OE1 . GLU A 1 159 ? 43.524 46.365 15.288 1.00 11.97 ? 159 GLU A OE1 1 ATOM 1137 O OE2 . GLU A 1 159 ? 42.171 47.530 13.917 1.00 10.93 ? 159 GLU A OE2 1 ATOM 1138 N N . PHE A 1 160 ? 45.784 51.412 13.727 1.00 8.29 ? 160 PHE A N 1 ATOM 1139 C CA . PHE A 1 160 ? 45.533 52.248 12.534 1.00 7.54 ? 160 PHE A CA 1 ATOM 1140 C C . PHE A 1 160 ? 44.593 51.521 11.588 1.00 7.71 ? 160 PHE A C 1 ATOM 1141 O O . PHE A 1 160 ? 44.736 50.314 11.340 1.00 8.31 ? 160 PHE A O 1 ATOM 1142 C CB . PHE A 1 160 ? 46.885 52.560 11.868 1.00 8.49 ? 160 PHE A CB 1 ATOM 1143 C CG . PHE A 1 160 ? 47.766 53.412 12.726 1.00 8.56 ? 160 PHE A CG 1 ATOM 1144 C CD1 . PHE A 1 160 ? 47.464 54.762 12.909 1.00 9.57 ? 160 PHE A CD1 1 ATOM 1145 C CD2 . PHE A 1 160 ? 48.846 52.836 13.415 1.00 9.42 ? 160 PHE A CD2 1 ATOM 1146 C CE1 . PHE A 1 160 ? 48.249 55.549 13.780 1.00 10.39 ? 160 PHE A CE1 1 ATOM 1147 C CE2 . PHE A 1 160 ? 49.616 53.607 14.263 1.00 10.59 ? 160 PHE A CE2 1 ATOM 1148 C CZ . PHE A 1 160 ? 49.334 54.934 14.445 1.00 10.84 ? 160 PHE A CZ 1 ATOM 1149 N N . VAL A 1 161 ? 43.607 52.274 11.128 1.00 7.75 ? 161 VAL A N 1 ATOM 1150 C CA . VAL A 1 161 ? 42.627 51.757 10.166 1.00 7.76 ? 161 VAL A CA 1 ATOM 1151 C C . VAL A 1 161 ? 42.826 52.564 8.892 1.00 7.65 ? 161 VAL A C 1 ATOM 1152 O O . VAL A 1 161 ? 42.920 53.795 8.893 1.00 8.25 ? 161 VAL A O 1 ATOM 1153 C CB . VAL A 1 161 ? 41.168 51.849 10.730 1.00 6.94 ? 161 VAL A CB 1 ATOM 1154 C CG1 . VAL A 1 161 ? 41.034 50.846 11.917 1.00 8.64 ? 161 VAL A CG1 1 ATOM 1155 C CG2 . VAL A 1 161 ? 40.825 53.242 11.202 1.00 7.89 ? 161 VAL A CG2 1 ATOM 1156 N N . THR A 1 162 ? 42.864 51.789 7.799 1.00 7.67 ? 162 THR A N 1 ATOM 1157 C CA . THR A 1 162 ? 43.185 52.259 6.409 1.00 8.10 ? 162 THR A CA 1 ATOM 1158 C C . THR A 1 162 ? 44.648 52.715 6.350 1.00 7.41 ? 162 THR A C 1 ATOM 1159 O O . THR A 1 162 ? 45.459 52.139 5.614 1.00 8.34 ? 162 THR A O 1 ATOM 1160 C CB . THR A 1 162 ? 42.326 53.391 5.913 1.00 7.80 ? 162 THR A CB 1 ATOM 1161 O OG1 . THR A 1 162 ? 40.934 53.061 6.005 1.00 9.12 ? 162 THR A OG1 1 ATOM 1162 C CG2 . THR A 1 162 ? 42.646 53.629 4.415 1.00 9.28 ? 162 THR A CG2 1 ATOM 1163 N N . GLY A 1 163 ? 44.983 53.778 7.078 1.00 7.51 ? 163 GLY A N 1 ATOM 1164 C CA . GLY A 1 163 ? 46.370 54.238 7.076 1.00 7.74 ? 163 GLY A CA 1 ATOM 1165 C C . GLY A 1 163 ? 46.694 55.194 5.960 1.00 7.26 ? 163 GLY A C 1 ATOM 1166 O O . GLY A 1 163 ? 47.867 55.384 5.648 1.00 7.84 ? 163 GLY A O 1 ATOM 1167 N N . GLY A 1 164 ? 45.664 55.764 5.318 1.00 6.73 ? 164 GLY A N 1 ATOM 1168 C CA . GLY A 1 164 ? 45.970 56.797 4.299 1.00 7.07 ? 164 GLY A CA 1 ATOM 1169 C C . GLY A 1 164 ? 46.272 58.133 4.949 1.00 6.59 ? 164 GLY A C 1 ATOM 1170 O O . GLY A 1 164 ? 45.991 58.351 6.147 1.00 7.03 ? 164 GLY A O 1 ATOM 1171 N N . TRP A 1 165 ? 46.877 59.035 4.186 1.00 6.44 ? 165 TRP A N 1 ATOM 1172 C CA . TRP A 1 165 ? 47.119 60.384 4.682 1.00 6.37 ? 165 TRP A CA 1 ATOM 1173 C C . TRP A 1 165 ? 45.788 60.999 5.161 1.00 6.39 ? 165 TRP A C 1 ATOM 1174 O O . TRP A 1 165 ? 45.761 61.753 6.171 1.00 6.99 ? 165 TRP A O 1 ATOM 1175 C CB . TRP A 1 165 ? 47.727 61.190 3.536 1.00 7.01 ? 165 TRP A CB 1 ATOM 1176 C CG . TRP A 1 165 ? 48.556 62.302 3.986 1.00 7.29 ? 165 TRP A CG 1 ATOM 1177 C CD1 . TRP A 1 165 ? 48.364 63.610 3.659 1.00 8.40 ? 165 TRP A CD1 1 ATOM 1178 C CD2 . TRP A 1 165 ? 49.762 62.248 4.793 1.00 8.28 ? 165 TRP A CD2 1 ATOM 1179 N NE1 . TRP A 1 165 ? 49.387 64.397 4.216 1.00 9.75 ? 165 TRP A NE1 1 ATOM 1180 C CE2 . TRP A 1 165 ? 50.229 63.581 4.912 1.00 8.39 ? 165 TRP A CE2 1 ATOM 1181 C CE3 . TRP A 1 165 ? 50.472 61.203 5.391 1.00 8.63 ? 165 TRP A CE3 1 ATOM 1182 C CZ2 . TRP A 1 165 ? 51.427 63.902 5.665 1.00 10.90 ? 165 TRP A CZ2 1 ATOM 1183 C CZ3 . TRP A 1 165 ? 51.651 61.511 6.108 1.00 11.06 ? 165 TRP A CZ3 1 ATOM 1184 C CH2 . TRP A 1 165 ? 52.095 62.860 6.223 1.00 11.78 ? 165 TRP A CH2 1 ATOM 1185 N N . VAL A 1 166 ? 44.708 60.707 4.441 1.00 6.15 ? 166 VAL A N 1 ATOM 1186 C CA . VAL A 1 166 ? 43.369 61.207 4.763 1.00 6.38 ? 166 VAL A CA 1 ATOM 1187 C C . VAL A 1 166 ? 42.365 60.054 4.582 1.00 6.45 ? 166 VAL A C 1 ATOM 1188 O O . VAL A 1 166 ? 42.756 58.924 4.318 1.00 7.52 ? 166 VAL A O 1 ATOM 1189 C CB . VAL A 1 166 ? 42.951 62.374 3.828 1.00 5.98 ? 166 VAL A CB 1 ATOM 1190 C CG1 . VAL A 1 166 ? 43.960 63.534 3.955 1.00 7.33 ? 166 VAL A CG1 1 ATOM 1191 C CG2 . VAL A 1 166 ? 42.832 61.880 2.361 1.00 7.25 ? 166 VAL A CG2 1 ATOM 1192 N N . MET A 1 167 ? 41.061 60.350 4.816 1.00 7.76 ? 167 MET A N 1 ATOM 1193 C CA . MET A 1 167 ? 39.943 59.400 4.507 1.00 6.36 ? 167 MET A CA 1 ATOM 1194 C C . MET A 1 167 ? 39.413 60.154 3.255 1.00 6.74 ? 167 MET A C 1 ATOM 1195 O O . MET A 1 167 ? 38.635 61.112 3.344 1.00 7.01 ? 167 MET A O 1 ATOM 1196 C CB . MET A 1 167 ? 38.969 59.403 5.660 1.00 6.83 ? 167 MET A CB 1 ATOM 1197 C CG . MET A 1 167 ? 37.683 58.633 5.333 1.00 6.51 ? 167 MET A CG 1 ATOM 1198 S SD . MET A 1 167 ? 36.520 58.721 6.698 1.00 7.82 ? 167 MET A SD 1 ATOM 1199 C CE . MET A 1 167 ? 37.488 57.959 8.055 1.00 8.90 ? 167 MET A CE 1 ATOM 1200 N N . PRO A 1 168 ? 39.800 59.694 2.053 1.00 6.07 ? 168 PRO A N 1 ATOM 1201 C CA . PRO A 1 168 ? 39.414 60.445 0.871 1.00 6.72 ? 168 PRO A CA 1 ATOM 1202 C C . PRO A 1 168 ? 37.995 60.462 0.409 1.00 5.63 ? 168 PRO A C 1 ATOM 1203 O O . PRO A 1 168 ? 37.245 59.540 0.633 1.00 6.64 ? 168 PRO A O 1 ATOM 1204 C CB . PRO A 1 168 ? 40.318 59.848 -0.245 1.00 6.61 ? 168 PRO A CB 1 ATOM 1205 C CG . PRO A 1 168 ? 40.446 58.422 0.168 1.00 7.46 ? 168 PRO A CG 1 ATOM 1206 C CD . PRO A 1 168 ? 40.630 58.516 1.715 1.00 6.37 ? 168 PRO A CD 1 ATOM 1207 N N . ASP A 1 169 ? 37.651 61.551 -0.264 1.00 6.69 ? 169 ASP A N 1 ATOM 1208 C CA . ASP A 1 169 ? 36.406 61.577 -1.044 1.00 6.12 ? 169 ASP A CA 1 ATOM 1209 C C . ASP A 1 169 ? 36.543 60.401 -2.025 1.00 6.25 ? 169 ASP A C 1 ATOM 1210 O O . ASP A 1 169 ? 37.643 60.070 -2.500 1.00 6.48 ? 169 ASP A O 1 ATOM 1211 C CB . ASP A 1 169 ? 36.389 62.871 -1.860 1.00 6.32 ? 169 ASP A CB 1 ATOM 1212 C CG . ASP A 1 169 ? 35.217 62.931 -2.812 1.00 6.58 ? 169 ASP A CG 1 ATOM 1213 O OD1 . ASP A 1 169 ? 34.135 62.411 -2.501 1.00 7.52 ? 169 ASP A OD1 1 ATOM 1214 O OD2 . ASP A 1 169 ? 35.368 63.536 -3.903 1.00 8.68 ? 169 ASP A OD2 1 ATOM 1215 N N . GLU A 1 170 ? 35.423 59.811 -2.364 1.00 5.88 ? 170 GLU A N 1 ATOM 1216 C CA . GLU A 1 170 ? 35.386 58.675 -3.328 1.00 6.21 ? 170 GLU A CA 1 ATOM 1217 C C . GLU A 1 170 ? 34.659 59.041 -4.618 1.00 5.97 ? 170 GLU A C 1 ATOM 1218 O O . GLU A 1 170 ? 34.680 58.241 -5.558 1.00 6.45 ? 170 GLU A O 1 ATOM 1219 C CB . GLU A 1 170 ? 34.765 57.444 -2.643 1.00 6.90 ? 170 GLU A CB 1 ATOM 1220 C CG . GLU A 1 170 ? 35.548 57.042 -1.362 1.00 7.04 ? 170 GLU A CG 1 ATOM 1221 C CD . GLU A 1 170 ? 34.993 55.802 -0.703 1.00 8.06 ? 170 GLU A CD 1 ATOM 1222 O OE1 . GLU A 1 170 ? 34.229 55.037 -1.324 1.00 7.94 ? 170 GLU A OE1 1 ATOM 1223 O OE2 . GLU A 1 170 ? 35.380 55.554 0.458 1.00 8.72 ? 170 GLU A OE2 1 ATOM 1224 N N . ALA A 1 171 ? 34.084 60.247 -4.699 1.00 6.39 ? 171 ALA A N 1 ATOM 1225 C CA . ALA A 1 171 ? 33.355 60.663 -5.919 1.00 5.61 ? 171 ALA A CA 1 ATOM 1226 C C . ALA A 1 171 ? 34.212 61.419 -6.912 1.00 6.03 ? 171 ALA A C 1 ATOM 1227 O O . ALA A 1 171 ? 34.239 61.085 -8.081 1.00 6.86 ? 171 ALA A O 1 ATOM 1228 C CB . ALA A 1 171 ? 32.157 61.526 -5.553 1.00 6.72 ? 171 ALA A CB 1 ATOM 1229 N N . ASN A 1 172 ? 34.912 62.441 -6.439 1.00 5.97 ? 172 ASN A N 1 ATOM 1230 C CA . ASN A 1 172 ? 35.656 63.309 -7.358 1.00 6.09 ? 172 ASN A CA 1 ATOM 1231 C C . ASN A 1 172 ? 37.112 62.925 -7.494 1.00 6.11 ? 172 ASN A C 1 ATOM 1232 O O . ASN A 1 172 ? 37.793 63.368 -8.431 1.00 6.38 ? 172 ASN A O 1 ATOM 1233 C CB . ASN A 1 172 ? 35.636 64.739 -6.795 1.00 6.34 ? 172 ASN A CB 1 ATOM 1234 C CG . ASN A 1 172 ? 34.234 65.284 -6.656 1.00 7.48 ? 172 ASN A CG 1 ATOM 1235 O OD1 . ASN A 1 172 ? 33.565 65.495 -7.650 1.00 9.24 ? 172 ASN A OD1 1 ATOM 1236 N ND2 . ASN A 1 172 ? 33.802 65.546 -5.429 1.00 8.50 ? 172 ASN A ND2 1 ATOM 1237 N N . SER A 1 173 ? 37.612 62.120 -6.582 1.00 5.82 ? 173 SER A N 1 ATOM 1238 C CA . SER A 1 173 ? 39.056 61.779 -6.562 1.00 6.13 ? 173 SER A CA 1 ATOM 1239 C C . SER A 1 173 ? 39.434 60.874 -7.702 1.00 6.16 ? 173 SER A C 1 ATOM 1240 O O . SER A 1 173 ? 38.721 59.951 -8.094 1.00 6.86 ? 173 SER A O 1 ATOM 1241 C CB . SER A 1 173 ? 39.373 61.120 -5.218 1.00 6.38 ? 173 SER A CB 1 ATOM 1242 O OG . SER A 1 173 ? 38.478 59.988 -5.033 1.00 6.92 ? 173 SER A OG 1 ATOM 1243 N N . HIS A 1 174 ? 40.608 61.155 -8.246 1.00 5.71 ? 174 HIS A N 1 ATOM 1244 C CA . HIS A 1 174 ? 41.142 60.263 -9.269 1.00 5.29 ? 174 HIS A CA 1 ATOM 1245 C C . HIS A 1 174 ? 41.779 59.072 -8.584 1.00 5.05 ? 174 HIS A C 1 ATOM 1246 O O . HIS A 1 174 ? 42.448 59.252 -7.562 1.00 5.40 ? 174 HIS A O 1 ATOM 1247 C CB . HIS A 1 174 ? 42.188 60.988 -10.122 1.00 6.27 ? 174 HIS A CB 1 ATOM 1248 C CG . HIS A 1 174 ? 42.431 60.311 -11.427 1.00 6.05 ? 174 HIS A CG 1 ATOM 1249 N ND1 . HIS A 1 174 ? 43.139 59.134 -11.534 1.00 6.87 ? 174 HIS A ND1 1 ATOM 1250 C CD2 . HIS A 1 174 ? 41.980 60.615 -12.664 1.00 6.98 ? 174 HIS A CD2 1 ATOM 1251 C CE1 . HIS A 1 174 ? 43.114 58.738 -12.792 1.00 7.03 ? 174 HIS A CE1 1 ATOM 1252 N NE2 . HIS A 1 174 ? 42.416 59.616 -13.492 1.00 7.50 ? 174 HIS A NE2 1 ATOM 1253 N N . TRP A 1 175 ? 41.641 57.865 -9.129 1.00 5.46 ? 175 TRP A N 1 ATOM 1254 C CA . TRP A 1 175 ? 42.256 56.698 -8.479 1.00 4.94 ? 175 TRP A CA 1 ATOM 1255 C C . TRP A 1 175 ? 43.755 56.857 -8.285 1.00 5.60 ? 175 TRP A C 1 ATOM 1256 O O . TRP A 1 175 ? 44.287 56.352 -7.299 1.00 5.88 ? 175 TRP A O 1 ATOM 1257 C CB . TRP A 1 175 ? 41.944 55.414 -9.295 1.00 6.17 ? 175 TRP A CB 1 ATOM 1258 C CG . TRP A 1 175 ? 42.795 55.196 -10.566 1.00 6.05 ? 175 TRP A CG 1 ATOM 1259 C CD1 . TRP A 1 175 ? 42.440 55.573 -11.854 1.00 6.18 ? 175 TRP A CD1 1 ATOM 1260 C CD2 . TRP A 1 175 ? 44.101 54.580 -10.660 1.00 6.47 ? 175 TRP A CD2 1 ATOM 1261 N NE1 . TRP A 1 175 ? 43.490 55.203 -12.712 1.00 7.21 ? 175 TRP A NE1 1 ATOM 1262 C CE2 . TRP A 1 175 ? 44.489 54.608 -11.991 1.00 6.57 ? 175 TRP A CE2 1 ATOM 1263 C CE3 . TRP A 1 175 ? 44.972 53.997 -9.714 1.00 7.54 ? 175 TRP A CE3 1 ATOM 1264 C CZ2 . TRP A 1 175 ? 45.719 54.090 -12.423 1.00 7.54 ? 175 TRP A CZ2 1 ATOM 1265 C CZ3 . TRP A 1 175 ? 46.172 53.462 -10.150 1.00 8.04 ? 175 TRP A CZ3 1 ATOM 1266 C CH2 . TRP A 1 175 ? 46.535 53.519 -11.488 1.00 8.07 ? 175 TRP A CH2 1 ATOM 1267 N N . ARG A 1 176 ? 44.423 57.572 -9.187 1.00 6.39 ? 176 ARG A N 1 ATOM 1268 C CA . ARG A 1 176 ? 45.882 57.746 -8.985 1.00 5.65 ? 176 ARG A CA 1 ATOM 1269 C C . ARG A 1 176 ? 46.150 58.518 -7.697 1.00 5.50 ? 176 ARG A C 1 ATOM 1270 O O . ARG A 1 176 ? 47.139 58.223 -7.016 1.00 6.33 ? 176 ARG A O 1 ATOM 1271 C CB . ARG A 1 176 ? 46.457 58.516 -10.206 1.00 7.13 ? 176 ARG A CB 1 ATOM 1272 C CG . ARG A 1 176 ? 46.447 57.633 -11.455 1.00 8.26 ? 176 ARG A CG 1 ATOM 1273 C CD . ARG A 1 176 ? 46.399 58.465 -12.744 1.00 9.72 ? 176 ARG A CD 1 ATOM 1274 N NE . ARG A 1 176 ? 47.550 59.340 -12.867 1.00 9.12 ? 176 ARG A NE 1 ATOM 1275 C CZ . ARG A 1 176 ? 47.675 60.180 -13.906 1.00 8.84 ? 176 ARG A CZ 1 ATOM 1276 N NH1 . ARG A 1 176 ? 46.727 60.218 -14.861 1.00 8.67 ? 176 ARG A NH1 1 ATOM 1277 N NH2 . ARG A 1 176 ? 48.639 61.104 -13.907 1.00 10.13 ? 176 ARG A NH2 1 ATOM 1278 N N . ASN A 1 177 ? 45.297 59.495 -7.347 1.00 5.39 ? 177 ASN A N 1 ATOM 1279 C CA . ASN A 1 177 ? 45.522 60.264 -6.113 1.00 5.63 ? 177 ASN A CA 1 ATOM 1280 C C . ASN A 1 177 ? 45.015 59.506 -4.902 1.00 5.89 ? 177 ASN A C 1 ATOM 1281 O O . ASN A 1 177 ? 45.529 59.721 -3.781 1.00 6.22 ? 177 ASN A O 1 ATOM 1282 C CB . ASN A 1 177 ? 44.895 61.643 -6.212 1.00 6.04 ? 177 ASN A CB 1 ATOM 1283 C CG . ASN A 1 177 ? 45.573 62.488 -7.251 1.00 6.85 ? 177 ASN A CG 1 ATOM 1284 O OD1 . ASN A 1 177 ? 46.753 62.296 -7.557 1.00 7.69 ? 177 ASN A OD1 1 ATOM 1285 N ND2 . ASN A 1 177 ? 44.855 63.463 -7.773 1.00 9.46 ? 177 ASN A ND2 1 ATOM 1286 N N . VAL A 1 178 ? 44.014 58.637 -5.071 1.00 6.05 ? 178 VAL A N 1 ATOM 1287 C CA . VAL A 1 178 ? 43.609 57.804 -3.927 1.00 5.77 ? 178 VAL A CA 1 ATOM 1288 C C . VAL A 1 178 ? 44.811 56.906 -3.593 1.00 5.42 ? 178 VAL A C 1 ATOM 1289 O O . VAL A 1 178 ? 45.141 56.746 -2.410 1.00 6.59 ? 178 VAL A O 1 ATOM 1290 C CB . VAL A 1 178 ? 42.376 56.946 -4.309 1.00 5.65 ? 178 VAL A CB 1 ATOM 1291 C CG1 . VAL A 1 178 ? 42.080 55.941 -3.193 1.00 7.65 ? 178 VAL A CG1 1 ATOM 1292 C CG2 . VAL A 1 178 ? 41.132 57.840 -4.520 1.00 7.34 ? 178 VAL A CG2 1 ATOM 1293 N N . LEU A 1 179 ? 45.457 56.319 -4.606 1.00 6.16 ? 179 LEU A N 1 ATOM 1294 C CA . LEU A 1 179 ? 46.646 55.498 -4.335 1.00 6.24 ? 179 LEU A CA 1 ATOM 1295 C C . LEU A 1 179 ? 47.768 56.335 -3.768 1.00 5.98 ? 179 LEU A C 1 ATOM 1296 O O . LEU A 1 179 ? 48.438 55.888 -2.831 1.00 6.59 ? 179 LEU A O 1 ATOM 1297 C CB . LEU A 1 179 ? 47.086 54.821 -5.656 1.00 6.71 ? 179 LEU A CB 1 ATOM 1298 C CG . LEU A 1 179 ? 48.406 53.981 -5.489 1.00 6.98 ? 179 LEU A CG 1 ATOM 1299 C CD1 . LEU A 1 179 ? 48.270 52.833 -4.428 1.00 8.34 ? 179 LEU A CD1 1 ATOM 1300 C CD2 . LEU A 1 179 ? 48.810 53.433 -6.863 1.00 8.48 ? 179 LEU A CD2 1 ATOM 1301 N N . LEU A 1 180 ? 47.947 57.553 -4.266 1.00 6.17 ? 180 LEU A N 1 ATOM 1302 C CA . LEU A 1 180 ? 49.062 58.407 -3.763 1.00 6.52 ? 180 LEU A CA 1 ATOM 1303 C C . LEU A 1 180 ? 48.885 58.644 -2.273 1.00 5.88 ? 180 LEU A C 1 ATOM 1304 O O . LEU A 1 180 ? 49.836 58.456 -1.489 1.00 6.34 ? 180 LEU A O 1 ATOM 1305 C CB . LEU A 1 180 ? 49.029 59.767 -4.506 1.00 6.33 ? 180 LEU A CB 1 ATOM 1306 C CG . LEU A 1 180 ? 50.177 60.730 -4.167 1.00 7.97 ? 180 LEU A CG 1 ATOM 1307 C CD1 . LEU A 1 180 ? 51.446 60.214 -4.841 1.00 8.89 ? 180 LEU A CD1 1 ATOM 1308 C CD2 . LEU A 1 180 ? 49.853 62.147 -4.663 1.00 8.51 ? 180 LEU A CD2 1 ATOM 1309 N N . GLN A 1 181 ? 47.684 59.045 -1.854 1.00 5.90 ? 181 GLN A N 1 ATOM 1310 C CA . GLN A 1 181 ? 47.545 59.352 -0.425 1.00 5.96 ? 181 GLN A CA 1 ATOM 1311 C C . GLN A 1 181 ? 47.584 58.106 0.447 1.00 6.04 ? 181 GLN A C 1 ATOM 1312 O O . GLN A 1 181 ? 48.071 58.178 1.588 1.00 6.08 ? 181 GLN A O 1 ATOM 1313 C CB . GLN A 1 181 ? 46.261 60.201 -0.215 1.00 6.20 ? 181 GLN A CB 1 ATOM 1314 C CG . GLN A 1 181 ? 44.920 59.460 -0.438 1.00 6.10 ? 181 GLN A CG 1 ATOM 1315 C CD . GLN A 1 181 ? 44.532 58.525 0.702 1.00 6.43 ? 181 GLN A CD 1 ATOM 1316 O OE1 . GLN A 1 181 ? 44.755 58.851 1.876 1.00 8.04 ? 181 GLN A OE1 1 ATOM 1317 N NE2 . GLN A 1 181 ? 43.909 57.406 0.357 1.00 7.30 ? 181 GLN A NE2 1 ATOM 1318 N N . LEU A 1 182 ? 47.094 56.976 -0.054 1.00 6.59 ? 182 LEU A N 1 ATOM 1319 C CA . LEU A 1 182 ? 47.166 55.728 0.696 1.00 6.44 ? 182 LEU A CA 1 ATOM 1320 C C . LEU A 1 182 ? 48.638 55.384 0.861 1.00 6.34 ? 182 LEU A C 1 ATOM 1321 O O . LEU A 1 182 ? 49.066 55.000 1.972 1.00 6.82 ? 182 LEU A O 1 ATOM 1322 C CB . LEU A 1 182 ? 46.418 54.606 -0.065 1.00 6.46 ? 182 LEU A CB 1 ATOM 1323 C CG . LEU A 1 182 ? 46.497 53.232 0.602 1.00 6.74 ? 182 LEU A CG 1 ATOM 1324 C CD1 . LEU A 1 182 ? 45.740 53.212 1.979 1.00 9.22 ? 182 LEU A CD1 1 ATOM 1325 C CD2 . LEU A 1 182 ? 45.892 52.161 -0.343 1.00 8.20 ? 182 LEU A CD2 1 ATOM 1326 N N . THR A 1 183 ? 49.411 55.488 -0.203 1.00 6.26 ? 183 THR A N 1 ATOM 1327 C CA . THR A 1 183 ? 50.825 55.178 -0.126 1.00 6.03 ? 183 THR A CA 1 ATOM 1328 C C . THR A 1 183 ? 51.554 56.156 0.813 1.00 6.40 ? 183 THR A C 1 ATOM 1329 O O . THR A 1 183 ? 52.455 55.720 1.577 1.00 6.74 ? 183 THR A O 1 ATOM 1330 C CB . THR A 1 183 ? 51.435 55.243 -1.548 1.00 6.85 ? 183 THR A CB 1 ATOM 1331 O OG1 . THR A 1 183 ? 50.747 54.309 -2.390 1.00 6.95 ? 183 THR A OG1 1 ATOM 1332 C CG2 . THR A 1 183 ? 52.915 54.818 -1.504 1.00 8.11 ? 183 THR A CG2 1 ATOM 1333 N N . GLU A 1 184 ? 51.193 57.431 0.821 1.00 6.21 ? 184 GLU A N 1 ATOM 1334 C CA . GLU A 1 184 ? 51.897 58.392 1.679 1.00 7.26 ? 184 GLU A CA 1 ATOM 1335 C C . GLU A 1 184 ? 51.677 57.998 3.128 1.00 7.26 ? 184 GLU A C 1 ATOM 1336 O O . GLU A 1 184 ? 52.621 57.976 3.923 1.00 8.21 ? 184 GLU A O 1 ATOM 1337 C CB . GLU A 1 184 ? 51.332 59.777 1.428 1.00 8.17 ? 184 GLU A CB 1 ATOM 1338 C CG . GLU A 1 184 ? 52.191 60.940 1.928 1.00 9.80 ? 184 GLU A CG 1 ATOM 1339 C CD . GLU A 1 184 ? 53.607 60.992 1.271 1.00 9.21 ? 184 GLU A CD 1 ATOM 1340 O OE1 . GLU A 1 184 ? 53.792 60.619 0.117 1.00 10.08 ? 184 GLU A OE1 1 ATOM 1341 O OE2 . GLU A 1 184 ? 54.512 61.440 1.971 1.00 12.23 ? 184 GLU A OE2 1 ATOM 1342 N N . GLY A 1 185 ? 50.448 57.695 3.516 1.00 6.99 ? 185 GLY A N 1 ATOM 1343 C CA . GLY A 1 185 ? 50.205 57.326 4.910 1.00 6.74 ? 185 GLY A CA 1 ATOM 1344 C C . GLY A 1 185 ? 50.791 55.991 5.251 1.00 7.22 ? 185 GLY A C 1 ATOM 1345 O O . GLY A 1 185 ? 51.384 55.865 6.344 1.00 7.90 ? 185 GLY A O 1 ATOM 1346 N N . GLN A 1 186 ? 50.649 54.997 4.403 1.00 7.32 ? 186 GLN A N 1 ATOM 1347 C CA . GLN A 1 186 ? 51.156 53.665 4.792 1.00 7.81 ? 186 GLN A CA 1 ATOM 1348 C C . GLN A 1 186 ? 52.673 53.632 4.759 1.00 7.52 ? 186 GLN A C 1 ATOM 1349 O O . GLN A 1 186 ? 53.270 52.877 5.542 1.00 7.82 ? 186 GLN A O 1 ATOM 1350 C CB . GLN A 1 186 ? 50.581 52.553 3.901 1.00 6.46 ? 186 GLN A CB 1 ATOM 1351 C CG . GLN A 1 186 ? 49.051 52.399 4.077 1.00 8.84 ? 186 GLN A CG 1 ATOM 1352 C CD . GLN A 1 186 ? 48.637 50.994 3.851 1.00 8.56 ? 186 GLN A CD 1 ATOM 1353 O OE1 . GLN A 1 186 ? 49.270 50.301 3.073 1.00 11.56 ? 186 GLN A OE1 1 ATOM 1354 N NE2 . GLN A 1 186 ? 47.599 50.535 4.530 1.00 9.27 ? 186 GLN A NE2 1 ATOM 1355 N N . THR A 1 187 ? 53.335 54.405 3.881 1.00 7.99 ? 187 THR A N 1 ATOM 1356 C CA . THR A 1 187 ? 54.810 54.370 3.874 1.00 8.04 ? 187 THR A CA 1 ATOM 1357 C C . THR A 1 187 ? 55.270 54.972 5.191 1.00 8.78 ? 187 THR A C 1 ATOM 1358 O O . THR A 1 187 ? 56.215 54.437 5.796 1.00 8.98 ? 187 THR A O 1 ATOM 1359 C CB . THR A 1 187 ? 55.294 55.136 2.683 1.00 7.03 ? 187 THR A CB 1 ATOM 1360 O OG1 . THR A 1 187 ? 54.832 54.462 1.502 1.00 8.63 ? 187 THR A OG1 1 ATOM 1361 C CG2 . THR A 1 187 ? 56.869 55.132 2.660 1.00 9.55 ? 187 THR A CG2 1 ATOM 1362 N N . TRP A 1 188 ? 54.617 56.028 5.650 1.00 8.04 ? 188 TRP A N 1 ATOM 1363 C CA . TRP A 1 188 ? 54.964 56.647 6.937 1.00 8.72 ? 188 TRP A CA 1 ATOM 1364 C C . TRP A 1 188 ? 54.736 55.628 8.075 1.00 8.72 ? 188 TRP A C 1 ATOM 1365 O O . TRP A 1 188 ? 55.617 55.416 8.962 1.00 9.15 ? 188 TRP A O 1 ATOM 1366 C CB . TRP A 1 188 ? 54.106 57.880 7.174 1.00 9.00 ? 188 TRP A CB 1 ATOM 1367 C CG . TRP A 1 188 ? 54.541 58.680 8.402 1.00 9.45 ? 188 TRP A CG 1 ATOM 1368 C CD1 . TRP A 1 188 ? 55.408 59.707 8.390 1.00 10.43 ? 188 TRP A CD1 1 ATOM 1369 C CD2 . TRP A 1 188 ? 54.208 58.416 9.775 1.00 9.76 ? 188 TRP A CD2 1 ATOM 1370 N NE1 . TRP A 1 188 ? 55.692 60.114 9.685 1.00 10.74 ? 188 TRP A NE1 1 ATOM 1371 C CE2 . TRP A 1 188 ? 54.969 59.342 10.557 1.00 10.17 ? 188 TRP A CE2 1 ATOM 1372 C CE3 . TRP A 1 188 ? 53.389 57.494 10.409 1.00 8.86 ? 188 TRP A CE3 1 ATOM 1373 C CZ2 . TRP A 1 188 ? 54.928 59.349 11.968 1.00 10.59 ? 188 TRP A CZ2 1 ATOM 1374 C CZ3 . TRP A 1 188 ? 53.360 57.485 11.807 1.00 9.76 ? 188 TRP A CZ3 1 ATOM 1375 C CH2 . TRP A 1 188 ? 54.124 58.408 12.563 1.00 9.97 ? 188 TRP A CH2 1 ATOM 1376 N N . LEU A 1 189 ? 53.611 54.922 8.054 1.00 7.66 ? 189 LEU A N 1 ATOM 1377 C CA . LEU A 1 189 ? 53.342 53.944 9.101 1.00 8.35 ? 189 LEU A CA 1 ATOM 1378 C C . LEU A 1 189 ? 54.331 52.820 9.114 1.00 8.96 ? 189 LEU A C 1 ATOM 1379 O O . LEU A 1 189 ? 54.705 52.340 10.219 1.00 9.97 ? 189 LEU A O 1 ATOM 1380 C CB . LEU A 1 189 ? 51.941 53.310 8.959 1.00 8.43 ? 189 LEU A CB 1 ATOM 1381 C CG . LEU A 1 189 ? 50.826 54.227 9.417 1.00 8.55 ? 189 LEU A CG 1 ATOM 1382 C CD1 . LEU A 1 189 ? 49.458 53.529 9.090 1.00 9.61 ? 189 LEU A CD1 1 ATOM 1383 C CD2 . LEU A 1 189 ? 50.888 54.452 11.001 1.00 9.36 ? 189 LEU A CD2 1 ATOM 1384 N N . LYS A 1 190 ? 54.782 52.342 7.967 1.00 8.78 ? 190 LYS A N 1 ATOM 1385 C CA . LYS A 1 190 ? 55.713 51.220 7.978 1.00 9.78 ? 190 LYS A CA 1 ATOM 1386 C C . LYS A 1 190 ? 57.046 51.678 8.551 1.00 10.22 ? 190 LYS A C 1 ATOM 1387 O O . LYS A 1 190 ? 57.655 50.957 9.351 1.00 11.49 ? 190 LYS A O 1 ATOM 1388 C CB . LYS A 1 190 ? 55.937 50.640 6.569 1.00 11.63 ? 190 LYS A CB 1 ATOM 1389 C CG . LYS A 1 190 ? 56.852 49.405 6.576 1.00 14.20 ? 190 LYS A CG 1 ATOM 1390 C CD . LYS A 1 190 ? 57.048 48.857 5.210 1.00 18.10 ? 190 LYS A CD 1 ATOM 1391 C CE . LYS A 1 190 ? 57.887 47.573 5.210 1.00 21.16 ? 190 LYS A CE 1 ATOM 1392 N NZ . LYS A 1 190 ? 58.129 47.150 3.767 1.00 21.51 ? 190 LYS A NZ 1 ATOM 1393 N N . GLN A 1 191 ? 57.465 52.858 8.152 1.00 10.51 ? 191 GLN A N 1 ATOM 1394 C CA . GLN A 1 191 ? 58.754 53.403 8.599 1.00 12.65 ? 191 GLN A CA 1 ATOM 1395 C C . GLN A 1 191 ? 58.792 53.692 10.091 1.00 13.56 ? 191 GLN A C 1 ATOM 1396 O O . GLN A 1 191 ? 59.740 53.273 10.783 1.00 15.36 ? 191 GLN A O 1 ATOM 1397 C CB . GLN A 1 191 ? 59.061 54.689 7.841 1.00 14.15 ? 191 GLN A CB 1 ATOM 1398 C CG . GLN A 1 191 ? 60.426 55.270 8.248 1.00 19.65 ? 191 GLN A CG 1 ATOM 1399 C CD . GLN A 1 191 ? 60.902 56.433 7.334 1.00 22.74 ? 191 GLN A CD 1 ATOM 1400 O OE1 . GLN A 1 191 ? 61.978 57.006 7.577 1.00 27.22 ? 191 GLN A OE1 1 ATOM 1401 N NE2 . GLN A 1 191 ? 60.128 56.771 6.308 1.00 24.72 ? 191 GLN A NE2 1 ATOM 1402 N N . PHE A 1 192 ? 57.784 54.364 10.596 1.00 11.56 ? 192 PHE A N 1 ATOM 1403 C CA . PHE A 1 192 ? 57.785 54.785 11.994 1.00 12.27 ? 192 PHE A CA 1 ATOM 1404 C C . PHE A 1 192 ? 57.021 53.946 12.999 1.00 12.89 ? 192 PHE A C 1 ATOM 1405 O O . PHE A 1 192 ? 57.357 53.969 14.194 1.00 15.26 ? 192 PHE A O 1 ATOM 1406 C CB . PHE A 1 192 ? 57.316 56.227 12.080 1.00 11.42 ? 192 PHE A CB 1 ATOM 1407 C CG . PHE A 1 192 ? 58.211 57.183 11.344 1.00 11.71 ? 192 PHE A CG 1 ATOM 1408 C CD1 . PHE A 1 192 ? 59.447 57.537 11.901 1.00 13.48 ? 192 PHE A CD1 1 ATOM 1409 C CD2 . PHE A 1 192 ? 57.884 57.662 10.064 1.00 12.56 ? 192 PHE A CD2 1 ATOM 1410 C CE1 . PHE A 1 192 ? 60.346 58.350 11.191 1.00 14.74 ? 192 PHE A CE1 1 ATOM 1411 C CE2 . PHE A 1 192 ? 58.755 58.464 9.352 1.00 12.82 ? 192 PHE A CE2 1 ATOM 1412 C CZ . PHE A 1 192 ? 60.015 58.816 9.929 1.00 14.43 ? 192 PHE A CZ 1 ATOM 1413 N N . MET A 1 193 ? 56.000 53.226 12.564 1.00 11.63 ? 193 MET A N 1 ATOM 1414 C CA . MET A 1 193 ? 55.223 52.415 13.496 1.00 11.46 ? 193 MET A CA 1 ATOM 1415 C C . MET A 1 193 ? 55.350 50.921 13.224 1.00 11.95 ? 193 MET A C 1 ATOM 1416 O O . MET A 1 193 ? 54.814 50.095 13.995 1.00 13.85 ? 193 MET A O 1 ATOM 1417 C CB . MET A 1 193 ? 53.733 52.814 13.411 1.00 11.31 ? 193 MET A CB 1 ATOM 1418 C CG A MET A 1 193 ? 53.379 54.177 14.048 0.50 10.37 ? 193 MET A CG 1 ATOM 1419 C CG B MET A 1 193 ? 53.598 54.400 13.679 0.50 15.69 ? 193 MET A CG 1 ATOM 1420 S SD A MET A 1 193 ? 53.521 54.157 15.870 0.50 11.45 ? 193 MET A SD 1 ATOM 1421 S SD B MET A 1 193 ? 54.607 55.180 14.928 0.50 18.20 ? 193 MET A SD 1 ATOM 1422 C CE A MET A 1 193 ? 54.734 55.453 16.160 0.50 12.66 ? 193 MET A CE 1 ATOM 1423 C CE B MET A 1 193 ? 53.832 54.504 16.398 0.50 16.90 ? 193 MET A CE 1 ATOM 1424 N N . ASN A 1 194 ? 56.007 50.565 12.119 1.00 12.47 ? 194 ASN A N 1 ATOM 1425 C CA . ASN A 1 194 ? 56.182 49.182 11.718 1.00 13.18 ? 194 ASN A CA 1 ATOM 1426 C C . ASN A 1 194 ? 54.885 48.392 11.610 1.00 13.36 ? 194 ASN A C 1 ATOM 1427 O O . ASN A 1 194 ? 54.777 47.229 12.049 1.00 14.37 ? 194 ASN A O 1 ATOM 1428 C CB . ASN A 1 194 ? 57.098 48.453 12.740 1.00 15.66 ? 194 ASN A CB 1 ATOM 1429 C CG . ASN A 1 194 ? 57.610 47.144 12.211 1.00 21.62 ? 194 ASN A CG 1 ATOM 1430 O OD1 . ASN A 1 194 ? 57.812 46.987 11.014 1.00 20.44 ? 194 ASN A OD1 1 ATOM 1431 N ND2 . ASN A 1 194 ? 57.837 46.211 13.128 1.00 26.61 ? 194 ASN A ND2 1 ATOM 1432 N N . VAL A 1 195 ? 53.872 49.026 11.023 1.00 11.85 ? 195 VAL A N 1 ATOM 1433 C CA . VAL A 1 195 ? 52.599 48.344 10.829 1.00 11.88 ? 195 VAL A CA 1 ATOM 1434 C C . VAL A 1 195 ? 52.016 48.800 9.498 1.00 10.79 ? 195 VAL A C 1 ATOM 1435 O O . VAL A 1 195 ? 52.281 49.902 9.047 1.00 10.32 ? 195 VAL A O 1 ATOM 1436 C CB . VAL A 1 195 ? 51.530 48.692 11.939 1.00 12.25 ? 195 VAL A CB 1 ATOM 1437 C CG1 . VAL A 1 195 ? 52.003 48.262 13.316 1.00 16.71 ? 195 VAL A CG1 1 ATOM 1438 C CG2 . VAL A 1 195 ? 51.176 50.172 11.954 1.00 13.90 ? 195 VAL A CG2 1 ATOM 1439 N N . THR A 1 196 ? 51.260 47.890 8.891 1.00 10.00 ? 196 THR A N 1 ATOM 1440 C CA . THR A 1 196 ? 50.533 48.152 7.617 1.00 10.25 ? 196 THR A CA 1 ATOM 1441 C C . THR A 1 196 ? 49.105 47.651 7.813 1.00 9.87 ? 196 THR A C 1 ATOM 1442 O O . THR A 1 196 ? 48.863 46.443 7.864 1.00 10.37 ? 196 THR A O 1 ATOM 1443 C CB . THR A 1 196 ? 51.141 47.409 6.421 1.00 10.57 ? 196 THR A CB 1 ATOM 1444 O OG1 . THR A 1 196 ? 52.525 47.792 6.276 1.00 12.83 ? 196 THR A OG1 1 ATOM 1445 C CG2 . THR A 1 196 ? 50.404 47.789 5.146 1.00 13.21 ? 196 THR A CG2 1 ATOM 1446 N N . PRO A 1 197 ? 48.116 48.569 7.911 1.00 8.77 ? 197 PRO A N 1 ATOM 1447 C CA . PRO A 1 197 ? 46.732 48.152 8.109 1.00 8.67 ? 197 PRO A CA 1 ATOM 1448 C C . PRO A 1 197 ? 46.215 47.294 6.972 1.00 9.15 ? 197 PRO A C 1 ATOM 1449 O O . PRO A 1 197 ? 46.574 47.536 5.793 1.00 8.96 ? 197 PRO A O 1 ATOM 1450 C CB . PRO A 1 197 ? 45.988 49.485 8.153 1.00 10.45 ? 197 PRO A CB 1 ATOM 1451 C CG . PRO A 1 197 ? 47.008 50.476 8.656 1.00 9.89 ? 197 PRO A CG 1 ATOM 1452 C CD . PRO A 1 197 ? 48.292 50.022 8.078 1.00 9.52 ? 197 PRO A CD 1 ATOM 1453 N N . THR A 1 198 ? 45.389 46.324 7.318 1.00 8.16 ? 198 THR A N 1 ATOM 1454 C CA . THR A 1 198 ? 44.738 45.488 6.306 1.00 8.87 ? 198 THR A CA 1 ATOM 1455 C C . THR A 1 198 ? 43.226 45.637 6.398 1.00 8.01 ? 198 THR A C 1 ATOM 1456 O O . THR A 1 198 ? 42.495 44.936 5.698 1.00 8.55 ? 198 THR A O 1 ATOM 1457 C CB . THR A 1 198 ? 45.076 43.995 6.454 1.00 10.03 ? 198 THR A CB 1 ATOM 1458 O OG1 . THR A 1 198 ? 44.672 43.583 7.757 1.00 11.90 ? 198 THR A OG1 1 ATOM 1459 C CG2 . THR A 1 198 ? 46.594 43.741 6.277 1.00 11.76 ? 198 THR A CG2 1 ATOM 1460 N N . ALA A 1 199 ? 42.738 46.516 7.275 1.00 7.81 ? 199 ALA A N 1 ATOM 1461 C CA . ALA A 1 199 ? 41.290 46.806 7.380 1.00 7.25 ? 199 ALA A CA 1 ATOM 1462 C C . ALA A 1 199 ? 41.130 48.310 7.142 1.00 8.06 ? 199 ALA A C 1 ATOM 1463 O O . ALA A 1 199 ? 41.890 49.116 7.718 1.00 7.55 ? 199 ALA A O 1 ATOM 1464 C CB . ALA A 1 199 ? 40.756 46.462 8.821 1.00 8.67 ? 199 ALA A CB 1 ATOM 1465 N N . SER A 1 200 ? 40.150 48.684 6.327 1.00 7.27 ? 200 SER A N 1 ATOM 1466 C CA . SER A 1 200 ? 39.861 50.070 6.017 1.00 7.14 ? 200 SER A CA 1 ATOM 1467 C C . SER A 1 200 ? 38.604 50.552 6.723 1.00 6.91 ? 200 SER A C 1 ATOM 1468 O O . SER A 1 200 ? 37.627 49.771 6.884 1.00 7.55 ? 200 SER A O 1 ATOM 1469 C CB . SER A 1 200 ? 39.726 50.202 4.504 1.00 7.79 ? 200 SER A CB 1 ATOM 1470 O OG . SER A 1 200 ? 39.555 51.575 4.124 1.00 10.37 ? 200 SER A OG 1 ATOM 1471 N N . TRP A 1 201 ? 38.615 51.827 7.103 1.00 7.56 ? 201 TRP A N 1 ATOM 1472 C CA . TRP A 1 201 ? 37.524 52.510 7.808 1.00 6.70 ? 201 TRP A CA 1 ATOM 1473 C C . TRP A 1 201 ? 37.173 53.768 7.048 1.00 6.48 ? 201 TRP A C 1 ATOM 1474 O O . TRP A 1 201 ? 37.986 54.712 7.044 1.00 8.34 ? 201 TRP A O 1 ATOM 1475 C CB . TRP A 1 201 ? 38.076 52.848 9.190 1.00 7.13 ? 201 TRP A CB 1 ATOM 1476 C CG . TRP A 1 201 ? 37.235 53.672 10.136 1.00 6.93 ? 201 TRP A CG 1 ATOM 1477 C CD1 . TRP A 1 201 ? 37.381 55.006 10.446 1.00 7.55 ? 201 TRP A CD1 1 ATOM 1478 C CD2 . TRP A 1 201 ? 36.264 53.165 11.066 1.00 8.01 ? 201 TRP A CD2 1 ATOM 1479 N NE1 . TRP A 1 201 ? 36.567 55.334 11.505 1.00 8.06 ? 201 TRP A NE1 1 ATOM 1480 C CE2 . TRP A 1 201 ? 35.876 54.240 11.913 1.00 8.26 ? 201 TRP A CE2 1 ATOM 1481 C CE3 . TRP A 1 201 ? 35.699 51.904 11.283 1.00 8.53 ? 201 TRP A CE3 1 ATOM 1482 C CZ2 . TRP A 1 201 ? 34.955 54.102 12.959 1.00 8.81 ? 201 TRP A CZ2 1 ATOM 1483 C CZ3 . TRP A 1 201 ? 34.766 51.749 12.343 1.00 9.08 ? 201 TRP A CZ3 1 ATOM 1484 C CH2 . TRP A 1 201 ? 34.414 52.852 13.161 1.00 9.86 ? 201 TRP A CH2 1 ATOM 1485 N N . ALA A 1 202 ? 35.988 53.791 6.428 1.00 6.97 ? 202 ALA A N 1 ATOM 1486 C CA . ALA A 1 202 ? 35.570 54.997 5.692 1.00 6.87 ? 202 ALA A CA 1 ATOM 1487 C C . ALA A 1 202 ? 34.148 55.373 6.101 1.00 7.19 ? 202 ALA A C 1 ATOM 1488 O O . ALA A 1 202 ? 33.153 54.992 5.488 1.00 7.81 ? 202 ALA A O 1 ATOM 1489 C CB . ALA A 1 202 ? 35.674 54.733 4.187 1.00 8.49 ? 202 ALA A CB 1 ATOM 1490 N N . ILE A 1 203 ? 34.072 56.068 7.233 1.00 7.08 ? 203 ILE A N 1 ATOM 1491 C CA . ILE A 1 203 ? 32.778 56.403 7.828 1.00 6.77 ? 203 ILE A CA 1 ATOM 1492 C C . ILE A 1 203 ? 32.133 57.664 7.316 1.00 7.10 ? 203 ILE A C 1 ATOM 1493 O O . ILE A 1 203 ? 30.946 57.877 7.590 1.00 8.17 ? 203 ILE A O 1 ATOM 1494 C CB . ILE A 1 203 ? 32.861 56.503 9.401 1.00 7.46 ? 203 ILE A CB 1 ATOM 1495 C CG1 . ILE A 1 203 ? 34.008 57.427 9.858 1.00 7.92 ? 203 ILE A CG1 1 ATOM 1496 C CG2 . ILE A 1 203 ? 33.125 55.065 9.943 1.00 8.48 ? 203 ILE A CG2 1 ATOM 1497 C CD1 . ILE A 1 203 ? 33.913 57.816 11.383 1.00 8.41 ? 203 ILE A CD1 1 ATOM 1498 N N . ASP A 1 204 ? 32.887 58.512 6.618 1.00 7.12 ? 204 ASP A N 1 ATOM 1499 C CA . ASP A 1 204 ? 32.327 59.802 6.219 1.00 7.13 ? 204 ASP A CA 1 ATOM 1500 C C . ASP A 1 204 ? 32.272 60.197 4.723 1.00 6.69 ? 204 ASP A C 1 ATOM 1501 O O . ASP A 1 204 ? 31.562 61.134 4.429 1.00 8.36 ? 204 ASP A O 1 ATOM 1502 C CB . ASP A 1 204 ? 33.017 60.939 6.998 1.00 7.65 ? 204 ASP A CB 1 ATOM 1503 C CG . ASP A 1 204 ? 32.103 62.165 7.216 1.00 7.84 ? 204 ASP A CG 1 ATOM 1504 O OD1 . ASP A 1 204 ? 30.874 62.047 7.334 1.00 8.65 ? 204 ASP A OD1 1 ATOM 1505 O OD2 . ASP A 1 204 ? 32.632 63.303 7.291 1.00 7.72 ? 204 ASP A OD2 1 ATOM 1506 N N . PRO A 1 205 ? 33.003 59.531 3.783 1.00 6.43 ? 205 PRO A N 1 ATOM 1507 C CA . PRO A 1 205 ? 32.827 60.012 2.380 1.00 6.92 ? 205 PRO A CA 1 ATOM 1508 C C . PRO A 1 205 ? 31.360 59.964 1.967 1.00 6.88 ? 205 PRO A C 1 ATOM 1509 O O . PRO A 1 205 ? 30.606 59.080 2.410 1.00 7.64 ? 205 PRO A O 1 ATOM 1510 C CB . PRO A 1 205 ? 33.741 59.085 1.555 1.00 8.49 ? 205 PRO A CB 1 ATOM 1511 C CG . PRO A 1 205 ? 34.844 58.610 2.590 1.00 9.78 ? 205 PRO A CG 1 ATOM 1512 C CD . PRO A 1 205 ? 33.991 58.428 3.896 1.00 8.41 ? 205 PRO A CD 1 ATOM 1513 N N . PHE A 1 206 ? 30.940 60.883 1.100 1.00 6.83 ? 206 PHE A N 1 ATOM 1514 C CA . PHE A 1 206 ? 29.468 61.045 0.828 1.00 7.14 ? 206 PHE A CA 1 ATOM 1515 C C . PHE A 1 206 ? 29.018 60.161 -0.348 1.00 7.31 ? 206 PHE A C 1 ATOM 1516 O O . PHE A 1 206 ? 28.804 60.589 -1.482 1.00 7.64 ? 206 PHE A O 1 ATOM 1517 C CB . PHE A 1 206 ? 29.177 62.536 0.579 1.00 7.59 ? 206 PHE A CB 1 ATOM 1518 C CG . PHE A 1 206 ? 30.036 63.488 1.420 1.00 6.58 ? 206 PHE A CG 1 ATOM 1519 C CD1 . PHE A 1 206 ? 30.228 63.254 2.772 1.00 7.53 ? 206 PHE A CD1 1 ATOM 1520 C CD2 . PHE A 1 206 ? 30.651 64.583 0.809 1.00 7.22 ? 206 PHE A CD2 1 ATOM 1521 C CE1 . PHE A 1 206 ? 31.018 64.095 3.532 1.00 8.10 ? 206 PHE A CE1 1 ATOM 1522 C CE2 . PHE A 1 206 ? 31.458 65.454 1.553 1.00 6.49 ? 206 PHE A CE2 1 ATOM 1523 C CZ . PHE A 1 206 ? 31.644 65.225 2.925 1.00 8.18 ? 206 PHE A CZ 1 ATOM 1524 N N . GLY A 1 207 ? 28.892 58.892 -0.008 1.00 6.82 ? 207 GLY A N 1 ATOM 1525 C CA . GLY A 1 207 ? 28.687 57.835 -1.004 1.00 6.82 ? 207 GLY A CA 1 ATOM 1526 C C . GLY A 1 207 ? 30.019 57.122 -1.210 1.00 6.80 ? 207 GLY A C 1 ATOM 1527 O O . GLY A 1 207 ? 31.127 57.662 -0.909 1.00 7.28 ? 207 GLY A O 1 ATOM 1528 N N . HIS A 1 208 ? 29.950 55.922 -1.796 1.00 6.90 ? 208 HIS A N 1 ATOM 1529 C CA . HIS A 1 208 ? 31.156 55.061 -1.860 1.00 7.13 ? 208 HIS A CA 1 ATOM 1530 C C . HIS A 1 208 ? 31.368 54.433 -3.213 1.00 6.40 ? 208 HIS A C 1 ATOM 1531 O O . HIS A 1 208 ? 30.392 54.075 -3.915 1.00 7.31 ? 208 HIS A O 1 ATOM 1532 C CB . HIS A 1 208 ? 31.048 53.947 -0.786 1.00 7.78 ? 208 HIS A CB 1 ATOM 1533 C CG . HIS A 1 208 ? 31.123 54.460 0.635 1.00 7.57 ? 208 HIS A CG 1 ATOM 1534 N ND1 . HIS A 1 208 ? 32.337 54.754 1.250 1.00 9.01 ? 208 HIS A ND1 1 ATOM 1535 C CD2 . HIS A 1 208 ? 30.153 54.744 1.529 1.00 9.09 ? 208 HIS A CD2 1 ATOM 1536 C CE1 . HIS A 1 208 ? 32.073 55.181 2.480 1.00 9.17 ? 208 HIS A CE1 1 ATOM 1537 N NE2 . HIS A 1 208 ? 30.771 55.184 2.674 1.00 10.13 ? 208 HIS A NE2 1 ATOM 1538 N N . SER A 1 209 ? 32.638 54.301 -3.591 1.00 6.73 ? 209 SER A N 1 ATOM 1539 C CA . SER A 1 209 ? 33.041 53.811 -4.919 1.00 5.58 ? 209 SER A CA 1 ATOM 1540 C C . SER A 1 209 ? 33.760 52.509 -4.855 1.00 6.26 ? 209 SER A C 1 ATOM 1541 O O . SER A 1 209 ? 34.567 52.269 -3.958 1.00 6.45 ? 209 SER A O 1 ATOM 1542 C CB . SER A 1 209 ? 34.011 54.863 -5.496 1.00 7.42 ? 209 SER A CB 1 ATOM 1543 O OG . SER A 1 209 ? 34.541 54.337 -6.714 1.00 6.90 ? 209 SER A OG 1 ATOM 1544 N N . PRO A 1 210 ? 33.515 51.614 -5.844 1.00 6.13 ? 210 PRO A N 1 ATOM 1545 C CA . PRO A 1 210 ? 34.211 50.312 -5.878 1.00 6.63 ? 210 PRO A CA 1 ATOM 1546 C C . PRO A 1 210 ? 35.693 50.513 -6.225 1.00 6.48 ? 210 PRO A C 1 ATOM 1547 O O . PRO A 1 210 ? 36.475 49.548 -6.156 1.00 6.59 ? 210 PRO A O 1 ATOM 1548 C CB . PRO A 1 210 ? 33.490 49.521 -6.983 1.00 7.14 ? 210 PRO A CB 1 ATOM 1549 C CG . PRO A 1 210 ? 32.903 50.642 -7.857 1.00 7.61 ? 210 PRO A CG 1 ATOM 1550 C CD . PRO A 1 210 ? 32.505 51.745 -6.915 1.00 6.22 ? 210 PRO A CD 1 ATOM 1551 N N . THR A 1 211 ? 36.131 51.745 -6.612 1.00 6.50 ? 211 THR A N 1 ATOM 1552 C CA . THR A 1 211 ? 37.559 51.954 -6.798 1.00 7.57 ? 211 THR A CA 1 ATOM 1553 C C . THR A 1 211 ? 38.297 51.700 -5.493 1.00 6.90 ? 211 THR A C 1 ATOM 1554 O O . THR A 1 211 ? 39.477 51.296 -5.517 1.00 7.24 ? 211 THR A O 1 ATOM 1555 C CB . THR A 1 211 ? 37.774 53.389 -7.280 1.00 7.05 ? 211 THR A CB 1 ATOM 1556 O OG1 . THR A 1 211 ? 37.203 53.440 -8.611 1.00 7.58 ? 211 THR A OG1 1 ATOM 1557 C CG2 . THR A 1 211 ? 39.245 53.788 -7.313 1.00 8.77 ? 211 THR A CG2 1 ATOM 1558 N N . MET A 1 212 ? 37.628 51.960 -4.354 1.00 6.62 ? 212 MET A N 1 ATOM 1559 C CA . MET A 1 212 ? 38.305 51.698 -3.086 1.00 7.12 ? 212 MET A CA 1 ATOM 1560 C C . MET A 1 212 ? 38.660 50.220 -2.870 1.00 6.98 ? 212 MET A C 1 ATOM 1561 O O . MET A 1 212 ? 39.838 49.907 -2.654 1.00 6.70 ? 212 MET A O 1 ATOM 1562 C CB . MET A 1 212 ? 37.500 52.271 -1.923 1.00 7.76 ? 212 MET A CB 1 ATOM 1563 C CG . MET A 1 212 ? 37.249 53.745 -2.024 1.00 8.39 ? 212 MET A CG 1 ATOM 1564 S SD . MET A 1 212 ? 38.702 54.737 -2.336 1.00 11.81 ? 212 MET A SD 1 ATOM 1565 C CE . MET A 1 212 ? 39.496 54.715 -0.751 1.00 12.94 ? 212 MET A CE 1 ATOM 1566 N N . PRO A 1 213 ? 37.697 49.275 -2.892 1.00 7.12 ? 213 PRO A N 1 ATOM 1567 C CA . PRO A 1 213 ? 38.128 47.873 -2.718 1.00 7.41 ? 213 PRO A CA 1 ATOM 1568 C C . PRO A 1 213 ? 39.100 47.470 -3.847 1.00 7.35 ? 213 PRO A C 1 ATOM 1569 O O . PRO A 1 213 ? 39.986 46.638 -3.626 1.00 8.34 ? 213 PRO A O 1 ATOM 1570 C CB . PRO A 1 213 ? 36.813 47.069 -2.769 1.00 7.90 ? 213 PRO A CB 1 ATOM 1571 C CG . PRO A 1 213 ? 35.795 48.045 -3.442 1.00 7.60 ? 213 PRO A CG 1 ATOM 1572 C CD . PRO A 1 213 ? 36.221 49.415 -2.892 1.00 7.11 ? 213 PRO A CD 1 ATOM 1573 N N . TYR A 1 214 ? 38.953 48.047 -5.061 1.00 7.21 ? 214 TYR A N 1 ATOM 1574 C CA . TYR A 1 214 ? 39.912 47.677 -6.108 1.00 7.12 ? 214 TYR A CA 1 ATOM 1575 C C . TYR A 1 214 ? 41.362 47.966 -5.664 1.00 7.30 ? 214 TYR A C 1 ATOM 1576 O O . TYR A 1 214 ? 42.262 47.086 -5.766 1.00 7.93 ? 214 TYR A O 1 ATOM 1577 C CB . TYR A 1 214 ? 39.607 48.488 -7.389 1.00 7.79 ? 214 TYR A CB 1 ATOM 1578 C CG . TYR A 1 214 ? 40.582 48.235 -8.544 1.00 10.12 ? 214 TYR A CG 1 ATOM 1579 C CD1 . TYR A 1 214 ? 40.345 47.165 -9.407 1.00 12.87 ? 214 TYR A CD1 1 ATOM 1580 C CD2 . TYR A 1 214 ? 41.654 49.092 -8.785 1.00 9.33 ? 214 TYR A CD2 1 ATOM 1581 C CE1 . TYR A 1 214 ? 41.158 46.970 -10.523 1.00 13.95 ? 214 TYR A CE1 1 ATOM 1582 C CE2 . TYR A 1 214 ? 42.458 48.913 -9.878 1.00 10.01 ? 214 TYR A CE2 1 ATOM 1583 C CZ . TYR A 1 214 ? 42.191 47.873 -10.743 1.00 12.29 ? 214 TYR A CZ 1 ATOM 1584 O OH . TYR A 1 214 ? 42.924 47.774 -11.927 1.00 12.60 ? 214 TYR A OH 1 ATOM 1585 N N . ILE A 1 215 ? 41.626 49.197 -5.239 1.00 6.66 ? 215 ILE A N 1 ATOM 1586 C CA . ILE A 1 215 ? 42.975 49.589 -4.825 1.00 6.89 ? 215 ILE A CA 1 ATOM 1587 C C . ILE A 1 215 ? 43.372 48.886 -3.510 1.00 6.59 ? 215 ILE A C 1 ATOM 1588 O O . ILE A 1 215 ? 44.470 48.370 -3.391 1.00 7.52 ? 215 ILE A O 1 ATOM 1589 C CB . ILE A 1 215 ? 43.038 51.123 -4.617 1.00 7.50 ? 215 ILE A CB 1 ATOM 1590 C CG1 . ILE A 1 215 ? 42.865 51.829 -5.961 1.00 8.53 ? 215 ILE A CG1 1 ATOM 1591 C CG2 . ILE A 1 215 ? 44.379 51.531 -3.886 1.00 8.82 ? 215 ILE A CG2 1 ATOM 1592 C CD1 . ILE A 1 215 ? 42.732 53.351 -5.814 1.00 11.27 ? 215 ILE A CD1 1 ATOM 1593 N N . LEU A 1 216 ? 42.465 48.829 -2.566 1.00 7.24 ? 216 LEU A N 1 ATOM 1594 C CA . LEU A 1 216 ? 42.788 48.210 -1.255 1.00 6.82 ? 216 LEU A CA 1 ATOM 1595 C C . LEU A 1 216 ? 43.118 46.729 -1.406 1.00 7.55 ? 216 LEU A C 1 ATOM 1596 O O . LEU A 1 216 ? 44.114 46.269 -0.823 1.00 7.54 ? 216 LEU A O 1 ATOM 1597 C CB . LEU A 1 216 ? 41.601 48.386 -0.293 1.00 7.03 ? 216 LEU A CB 1 ATOM 1598 C CG . LEU A 1 216 ? 41.230 49.822 0.075 1.00 7.63 ? 216 LEU A CG 1 ATOM 1599 C CD1 . LEU A 1 216 ? 39.922 49.785 0.840 1.00 9.28 ? 216 LEU A CD1 1 ATOM 1600 C CD2 . LEU A 1 216 ? 42.353 50.467 0.961 1.00 9.34 ? 216 LEU A CD2 1 ATOM 1601 N N . GLN A 1 217 ? 42.331 45.997 -2.213 1.00 7.25 ? 217 GLN A N 1 ATOM 1602 C CA . GLN A 1 217 ? 42.617 44.571 -2.381 1.00 8.09 ? 217 GLN A CA 1 ATOM 1603 C C . GLN A 1 217 ? 43.984 44.327 -3.059 1.00 9.08 ? 217 GLN A C 1 ATOM 1604 O O . GLN A 1 217 ? 44.617 43.317 -2.800 1.00 10.35 ? 217 GLN A O 1 ATOM 1605 C CB . GLN A 1 217 ? 41.434 43.957 -3.144 1.00 9.33 ? 217 GLN A CB 1 ATOM 1606 C CG . GLN A 1 217 ? 41.443 42.403 -3.189 1.00 10.70 ? 217 GLN A CG 1 ATOM 1607 C CD . GLN A 1 217 ? 42.350 41.843 -4.242 1.00 13.74 ? 217 GLN A CD 1 ATOM 1608 O OE1 . GLN A 1 217 ? 42.496 42.416 -5.289 1.00 15.51 ? 217 GLN A OE1 1 ATOM 1609 N NE2 . GLN A 1 217 ? 42.918 40.667 -3.987 1.00 14.74 ? 217 GLN A NE2 1 ATOM 1610 N N . LYS A 1 218 ? 44.446 45.263 -3.884 1.00 8.04 ? 218 LYS A N 1 ATOM 1611 C CA . LYS A 1 218 ? 45.756 45.150 -4.534 1.00 8.32 ? 218 LYS A CA 1 ATOM 1612 C C . LYS A 1 218 ? 46.862 45.774 -3.671 1.00 8.12 ? 218 LYS A C 1 ATOM 1613 O O . LYS A 1 218 ? 48.025 45.849 -4.107 1.00 8.49 ? 218 LYS A O 1 ATOM 1614 C CB . LYS A 1 218 ? 45.680 45.875 -5.883 1.00 8.37 ? 218 LYS A CB 1 ATOM 1615 C CG . LYS A 1 218 ? 44.892 45.052 -6.904 1.00 9.61 ? 218 LYS A CG 1 ATOM 1616 C CD . LYS A 1 218 ? 44.588 45.935 -8.158 1.00 10.01 ? 218 LYS A CD 1 ATOM 1617 C CE . LYS A 1 218 ? 44.145 45.123 -9.355 1.00 14.10 ? 218 LYS A CE 1 ATOM 1618 N NZ . LYS A 1 218 ? 43.084 44.073 -9.184 1.00 13.70 ? 218 LYS A NZ 1 ATOM 1619 N N . SER A 1 219 ? 46.514 46.204 -2.465 1.00 7.96 ? 219 SER A N 1 ATOM 1620 C CA . SER A 1 219 ? 47.428 46.798 -1.487 1.00 8.05 ? 219 SER A CA 1 ATOM 1621 C C . SER A 1 219 ? 47.437 46.032 -0.174 1.00 7.80 ? 219 SER A C 1 ATOM 1622 O O . SER A 1 219 ? 47.746 46.610 0.849 1.00 8.34 ? 219 SER A O 1 ATOM 1623 C CB . SER A 1 219 ? 47.057 48.266 -1.242 1.00 8.22 ? 219 SER A CB 1 ATOM 1624 O OG . SER A 1 219 ? 47.093 48.989 -2.494 1.00 8.63 ? 219 SER A OG 1 ATOM 1625 N N . GLY A 1 220 ? 47.086 44.738 -0.255 1.00 7.64 ? 220 GLY A N 1 ATOM 1626 C CA . GLY A 1 220 ? 47.155 43.865 0.930 1.00 9.21 ? 220 GLY A CA 1 ATOM 1627 C C . GLY A 1 220 ? 45.950 43.824 1.853 1.00 8.91 ? 220 GLY A C 1 ATOM 1628 O O . GLY A 1 220 ? 45.963 43.072 2.835 1.00 10.12 ? 220 GLY A O 1 ATOM 1629 N N . PHE A 1 221 ? 44.907 44.596 1.557 1.00 7.99 ? 221 PHE A N 1 ATOM 1630 C CA . PHE A 1 221 ? 43.784 44.605 2.472 1.00 8.05 ? 221 PHE A CA 1 ATOM 1631 C C . PHE A 1 221 ? 42.940 43.372 2.397 1.00 8.32 ? 221 PHE A C 1 ATOM 1632 O O . PHE A 1 221 ? 42.853 42.697 1.357 1.00 9.30 ? 221 PHE A O 1 ATOM 1633 C CB . PHE A 1 221 ? 42.889 45.838 2.248 1.00 7.17 ? 221 PHE A CB 1 ATOM 1634 C CG . PHE A 1 221 ? 43.459 47.095 2.773 1.00 6.71 ? 221 PHE A CG 1 ATOM 1635 C CD1 . PHE A 1 221 ? 44.583 47.703 2.173 1.00 7.73 ? 221 PHE A CD1 1 ATOM 1636 C CD2 . PHE A 1 221 ? 42.866 47.716 3.884 1.00 7.59 ? 221 PHE A CD2 1 ATOM 1637 C CE1 . PHE A 1 221 ? 45.078 48.857 2.668 1.00 7.71 ? 221 PHE A CE1 1 ATOM 1638 C CE2 . PHE A 1 221 ? 43.377 48.916 4.379 1.00 8.28 ? 221 PHE A CE2 1 ATOM 1639 C CZ . PHE A 1 221 ? 44.496 49.495 3.770 1.00 7.42 ? 221 PHE A CZ 1 ATOM 1640 N N . LYS A 1 222 ? 42.313 43.092 3.529 1.00 8.75 ? 222 LYS A N 1 ATOM 1641 C CA . LYS A 1 222 ? 41.430 41.955 3.641 1.00 9.38 ? 222 LYS A CA 1 ATOM 1642 C C . LYS A 1 222 ? 40.013 42.355 4.011 1.00 9.20 ? 222 LYS A C 1 ATOM 1643 O O . LYS A 1 222 ? 39.106 41.570 3.807 1.00 9.26 ? 222 LYS A O 1 ATOM 1644 C CB . LYS A 1 222 ? 41.951 40.980 4.702 1.00 11.58 ? 222 LYS A CB 1 ATOM 1645 C CG . LYS A 1 222 ? 43.361 40.480 4.471 1.00 14.83 ? 222 LYS A CG 1 ATOM 1646 C CD . LYS A 1 222 ? 43.563 39.852 3.110 1.00 18.77 ? 222 LYS A CD 1 ATOM 1647 C CE . LYS A 1 222 ? 44.971 39.244 3.023 1.00 21.01 ? 222 LYS A CE 1 ATOM 1648 N NZ A LYS A 1 222 ? 45.180 38.298 4.158 0.50 21.75 ? 222 LYS A NZ 1 ATOM 1649 N NZ B LYS A 1 222 ? 45.120 38.391 1.681 0.50 21.30 ? 222 LYS A NZ 1 ATOM 1650 N N . ASN A 1 223 ? 39.798 43.573 4.510 1.00 7.48 ? 223 ASN A N 1 ATOM 1651 C CA . ASN A 1 223 ? 38.454 43.978 4.939 1.00 7.66 ? 223 ASN A CA 1 ATOM 1652 C C . ASN A 1 223 ? 38.307 45.490 4.834 1.00 7.18 ? 223 ASN A C 1 ATOM 1653 O O . ASN A 1 223 ? 39.284 46.216 4.932 1.00 7.73 ? 223 ASN A O 1 ATOM 1654 C CB . ASN A 1 223 ? 38.233 43.625 6.454 1.00 8.59 ? 223 ASN A CB 1 ATOM 1655 C CG . ASN A 1 223 ? 38.302 42.152 6.733 1.00 9.07 ? 223 ASN A CG 1 ATOM 1656 O OD1 . ASN A 1 223 ? 39.351 41.642 7.209 1.00 11.45 ? 223 ASN A OD1 1 ATOM 1657 N ND2 . ASN A 1 223 ? 37.251 41.444 6.424 1.00 7.71 ? 223 ASN A ND2 1 ATOM 1658 N N . MET A 1 224 ? 37.067 45.916 4.672 1.00 6.77 ? 224 MET A N 1 ATOM 1659 C CA . MET A 1 224 ? 36.782 47.368 4.650 1.00 6.97 ? 224 MET A CA 1 ATOM 1660 C C . MET A 1 224 ? 35.384 47.648 5.216 1.00 7.48 ? 224 MET A C 1 ATOM 1661 O O . MET A 1 224 ? 34.479 46.762 5.220 1.00 7.74 ? 224 MET A O 1 ATOM 1662 C CB . MET A 1 224 ? 36.907 47.980 3.234 1.00 8.16 ? 224 MET A CB 1 ATOM 1663 C CG . MET A 1 224 ? 35.896 47.384 2.235 1.00 8.16 ? 224 MET A CG 1 ATOM 1664 S SD . MET A 1 224 ? 36.048 48.182 0.609 1.00 9.27 ? 224 MET A SD 1 ATOM 1665 C CE . MET A 1 224 ? 35.593 49.765 1.048 1.00 13.60 ? 224 MET A CE 1 ATOM 1666 N N . LEU A 1 225 ? 35.216 48.878 5.696 1.00 7.56 ? 225 LEU A N 1 ATOM 1667 C CA . LEU A 1 225 ? 33.978 49.328 6.284 1.00 7.02 ? 225 LEU A CA 1 ATOM 1668 C C . LEU A 1 225 ? 33.554 50.627 5.629 1.00 6.77 ? 225 LEU A C 1 ATOM 1669 O O . LEU A 1 225 ? 34.349 51.533 5.437 1.00 7.07 ? 225 LEU A O 1 ATOM 1670 C CB . LEU A 1 225 ? 34.153 49.478 7.814 1.00 7.85 ? 225 LEU A CB 1 ATOM 1671 C CG . LEU A 1 225 ? 32.935 50.076 8.519 1.00 7.42 ? 225 LEU A CG 1 ATOM 1672 C CD1 . LEU A 1 225 ? 32.839 49.491 9.965 1.00 8.49 ? 225 LEU A CD1 1 ATOM 1673 C CD2 . LEU A 1 225 ? 32.997 51.625 8.594 1.00 8.73 ? 225 LEU A CD2 1 ATOM 1674 N N . ILE A 1 226 ? 32.262 50.726 5.375 1.00 6.88 ? 226 ILE A N 1 ATOM 1675 C CA . ILE A 1 226 ? 31.641 51.936 4.782 1.00 7.34 ? 226 ILE A CA 1 ATOM 1676 C C . ILE A 1 226 ? 30.392 52.313 5.544 1.00 6.61 ? 226 ILE A C 1 ATOM 1677 O O . ILE A 1 226 ? 29.836 51.488 6.296 1.00 8.40 ? 226 ILE A O 1 ATOM 1678 C CB . ILE A 1 226 ? 31.353 51.759 3.251 1.00 7.18 ? 226 ILE A CB 1 ATOM 1679 C CG1 . ILE A 1 226 ? 30.287 50.670 3.035 1.00 8.27 ? 226 ILE A CG1 1 ATOM 1680 C CG2 . ILE A 1 226 ? 32.685 51.388 2.517 1.00 8.20 ? 226 ILE A CG2 1 ATOM 1681 C CD1 . ILE A 1 226 ? 29.902 50.499 1.519 1.00 9.21 ? 226 ILE A CD1 1 ATOM 1682 N N . GLN A 1 227 ? 29.967 53.564 5.387 1.00 8.24 ? 227 GLN A N 1 ATOM 1683 C CA . GLN A 1 227 ? 28.795 54.107 6.126 1.00 7.93 ? 227 GLN A CA 1 ATOM 1684 C C . GLN A 1 227 ? 27.803 54.930 5.350 1.00 8.14 ? 227 GLN A C 1 ATOM 1685 O O . GLN A 1 227 ? 26.605 54.708 5.504 1.00 8.92 ? 227 GLN A O 1 ATOM 1686 C CB . GLN A 1 227 ? 29.318 54.939 7.335 1.00 8.78 ? 227 GLN A CB 1 ATOM 1687 C CG . GLN A 1 227 ? 28.344 56.000 7.909 1.00 9.52 ? 227 GLN A CG 1 ATOM 1688 C CD . GLN A 1 227 ? 27.009 55.460 8.424 1.00 9.10 ? 227 GLN A CD 1 ATOM 1689 O OE1 . GLN A 1 227 ? 26.902 54.281 8.817 1.00 10.61 ? 227 GLN A OE1 1 ATOM 1690 N NE2 . GLN A 1 227 ? 25.993 56.317 8.421 1.00 10.33 ? 227 GLN A NE2 1 ATOM 1691 N N . ARG A 1 228 ? 28.234 55.857 4.504 1.00 7.91 ? 228 ARG A N 1 ATOM 1692 C CA . ARG A 1 228 ? 27.251 56.740 3.891 1.00 7.45 ? 228 ARG A CA 1 ATOM 1693 C C . ARG A 1 228 ? 26.721 56.180 2.595 1.00 7.72 ? 228 ARG A C 1 ATOM 1694 O O . ARG A 1 228 ? 27.285 56.409 1.538 1.00 8.30 ? 228 ARG A O 1 ATOM 1695 C CB . ARG A 1 228 ? 27.867 58.155 3.687 1.00 7.75 ? 228 ARG A CB 1 ATOM 1696 C CG . ARG A 1 228 ? 28.072 58.917 4.978 1.00 7.87 ? 228 ARG A CG 1 ATOM 1697 C CD . ARG A 1 228 ? 28.338 60.403 4.636 1.00 8.16 ? 228 ARG A CD 1 ATOM 1698 N NE . ARG A 1 228 ? 28.672 61.247 5.794 1.00 8.43 ? 228 ARG A NE 1 ATOM 1699 C CZ . ARG A 1 228 ? 27.783 61.936 6.505 1.00 9.67 ? 228 ARG A CZ 1 ATOM 1700 N NH1 . ARG A 1 228 ? 26.485 61.841 6.209 1.00 10.30 ? 228 ARG A NH1 1 ATOM 1701 N NH2 . ARG A 1 228 ? 28.200 62.790 7.429 1.00 10.95 ? 228 ARG A NH2 1 ATOM 1702 N N . THR A 1 229 ? 25.684 55.356 2.724 1.00 7.82 ? 229 THR A N 1 ATOM 1703 C CA . THR A 1 229 ? 24.966 54.835 1.580 1.00 7.91 ? 229 THR A CA 1 ATOM 1704 C C . THR A 1 229 ? 23.494 55.235 1.792 1.00 7.58 ? 229 THR A C 1 ATOM 1705 O O . THR A 1 229 ? 23.025 55.525 2.905 1.00 8.48 ? 229 THR A O 1 ATOM 1706 C CB . THR A 1 229 ? 25.065 53.303 1.465 1.00 7.43 ? 229 THR A CB 1 ATOM 1707 O OG1 . THR A 1 229 ? 24.483 52.739 2.629 1.00 9.50 ? 229 THR A OG1 1 ATOM 1708 C CG2 . THR A 1 229 ? 26.528 52.898 1.410 1.00 8.85 ? 229 THR A CG2 1 ATOM 1709 N N . HIS A 1 230 ? 22.815 55.328 0.661 1.00 7.92 ? 230 HIS A N 1 ATOM 1710 C CA . HIS A 1 230 ? 21.406 55.782 0.689 1.00 8.65 ? 230 HIS A CA 1 ATOM 1711 C C . HIS A 1 230 ? 20.572 55.036 1.738 1.00 8.34 ? 230 HIS A C 1 ATOM 1712 O O . HIS A 1 230 ? 20.640 53.803 1.811 1.00 8.59 ? 230 HIS A O 1 ATOM 1713 C CB . HIS A 1 230 ? 20.858 55.549 -0.738 1.00 8.49 ? 230 HIS A CB 1 ATOM 1714 C CG . HIS A 1 230 ? 19.564 56.246 -1.038 1.00 8.63 ? 230 HIS A CG 1 ATOM 1715 N ND1 . HIS A 1 230 ? 18.390 55.986 -0.370 1.00 9.30 ? 230 HIS A ND1 1 ATOM 1716 C CD2 . HIS A 1 230 ? 19.257 57.159 -2.003 1.00 9.57 ? 230 HIS A CD2 1 ATOM 1717 C CE1 . HIS A 1 230 ? 17.418 56.707 -0.897 1.00 9.72 ? 230 HIS A CE1 1 ATOM 1718 N NE2 . HIS A 1 230 ? 17.910 57.429 -1.894 1.00 8.84 ? 230 HIS A NE2 1 ATOM 1719 N N . TYR A 1 231 ? 19.773 55.797 2.504 1.00 8.77 ? 231 TYR A N 1 ATOM 1720 C CA . TYR A 1 231 ? 18.960 55.159 3.538 1.00 8.79 ? 231 TYR A CA 1 ATOM 1721 C C . TYR A 1 231 ? 18.070 54.038 2.973 1.00 9.54 ? 231 TYR A C 1 ATOM 1722 O O . TYR A 1 231 ? 17.819 53.068 3.679 1.00 9.60 ? 231 TYR A O 1 ATOM 1723 C CB . TYR A 1 231 ? 18.127 56.207 4.272 1.00 10.15 ? 231 TYR A CB 1 ATOM 1724 C CG . TYR A 1 231 ? 17.135 56.984 3.385 1.00 10.41 ? 231 TYR A CG 1 ATOM 1725 C CD1 . TYR A 1 231 ? 15.839 56.492 3.142 1.00 10.36 ? 231 TYR A CD1 1 ATOM 1726 C CD2 . TYR A 1 231 ? 17.479 58.230 2.795 1.00 10.01 ? 231 TYR A CD2 1 ATOM 1727 C CE1 . TYR A 1 231 ? 14.938 57.204 2.379 1.00 11.15 ? 231 TYR A CE1 1 ATOM 1728 C CE2 . TYR A 1 231 ? 16.611 58.924 2.025 1.00 10.36 ? 231 TYR A CE2 1 ATOM 1729 C CZ . TYR A 1 231 ? 15.309 58.412 1.814 1.00 10.24 ? 231 TYR A CZ 1 ATOM 1730 O OH . TYR A 1 231 ? 14.392 59.151 1.059 1.00 12.27 ? 231 TYR A OH 1 ATOM 1731 N N . SER A 1 232 ? 17.642 54.129 1.719 1.00 8.97 ? 232 SER A N 1 ATOM 1732 C CA . SER A 1 232 ? 16.801 53.063 1.147 1.00 10.50 ? 232 SER A CA 1 ATOM 1733 C C . SER A 1 232 ? 17.625 51.796 0.887 1.00 9.94 ? 232 SER A C 1 ATOM 1734 O O . SER A 1 232 ? 17.131 50.666 1.016 1.00 10.39 ? 232 SER A O 1 ATOM 1735 C CB . SER A 1 232 ? 16.172 53.494 -0.153 1.00 11.67 ? 232 SER A CB 1 ATOM 1736 O OG . SER A 1 232 ? 15.208 54.504 0.060 1.00 13.04 ? 232 SER A OG 1 ATOM 1737 N N . VAL A 1 233 ? 18.902 51.972 0.516 1.00 10.09 ? 233 VAL A N 1 ATOM 1738 C CA . VAL A 1 233 ? 19.794 50.837 0.320 1.00 9.72 ? 233 VAL A CA 1 ATOM 1739 C C . VAL A 1 233 ? 20.091 50.157 1.679 1.00 9.62 ? 233 VAL A C 1 ATOM 1740 O O . VAL A 1 233 ? 20.090 48.921 1.775 1.00 9.84 ? 233 VAL A O 1 ATOM 1741 C CB . VAL A 1 233 ? 21.135 51.326 -0.363 1.00 9.43 ? 233 VAL A CB 1 ATOM 1742 C CG1 . VAL A 1 233 ? 22.189 50.219 -0.347 1.00 9.79 ? 233 VAL A CG1 1 ATOM 1743 C CG2 . VAL A 1 233 ? 20.834 51.713 -1.829 1.00 9.82 ? 233 VAL A CG2 1 ATOM 1744 N N . LYS A 1 234 ? 20.375 50.939 2.721 1.00 8.80 ? 234 LYS A N 1 ATOM 1745 C CA . LYS A 1 234 ? 20.564 50.322 4.039 1.00 9.74 ? 234 LYS A CA 1 ATOM 1746 C C . LYS A 1 234 ? 19.353 49.479 4.435 1.00 9.88 ? 234 LYS A C 1 ATOM 1747 O O . LYS A 1 234 ? 19.515 48.379 4.941 1.00 9.91 ? 234 LYS A O 1 ATOM 1748 C CB . LYS A 1 234 ? 20.782 51.408 5.091 1.00 8.97 ? 234 LYS A CB 1 ATOM 1749 C CG . LYS A 1 234 ? 22.183 52.057 5.005 1.00 9.24 ? 234 LYS A CG 1 ATOM 1750 C CD . LYS A 1 234 ? 22.190 53.355 5.780 1.00 9.19 ? 234 LYS A CD 1 ATOM 1751 C CE . LYS A 1 234 ? 23.609 54.058 5.730 1.00 8.45 ? 234 LYS A CE 1 ATOM 1752 N NZ . LYS A 1 234 ? 24.501 53.499 6.848 1.00 9.01 ? 234 LYS A NZ 1 ATOM 1753 N N . LYS A 1 235 ? 18.153 50.017 4.230 1.00 10.06 ? 235 LYS A N 1 ATOM 1754 C CA . LYS A 1 235 ? 16.944 49.242 4.621 1.00 10.42 ? 235 LYS A CA 1 ATOM 1755 C C . LYS A 1 235 ? 16.834 47.959 3.810 1.00 10.07 ? 235 LYS A C 1 ATOM 1756 O O . LYS A 1 235 ? 16.605 46.873 4.389 1.00 11.21 ? 235 LYS A O 1 ATOM 1757 C CB . LYS A 1 235 ? 15.718 50.123 4.447 1.00 11.34 ? 235 LYS A CB 1 ATOM 1758 C CG . LYS A 1 235 ? 14.392 49.391 4.861 1.00 11.32 ? 235 LYS A CG 1 ATOM 1759 C CD . LYS A 1 235 ? 13.240 50.358 4.764 1.00 13.41 ? 235 LYS A CD 1 ATOM 1760 C CE . LYS A 1 235 ? 11.921 49.708 5.247 1.00 14.79 ? 235 LYS A CE 1 ATOM 1761 N NZ . LYS A 1 235 ? 10.811 50.691 5.029 1.00 20.51 ? 235 LYS A NZ 1 ATOM 1762 N N . GLU A 1 236 ? 17.027 48.040 2.509 1.00 10.25 ? 236 GLU A N 1 ATOM 1763 C CA . GLU A 1 236 ? 16.909 46.886 1.660 1.00 11.11 ? 236 GLU A CA 1 ATOM 1764 C C . GLU A 1 236 ? 17.937 45.804 1.991 1.00 11.43 ? 236 GLU A C 1 ATOM 1765 O O . GLU A 1 236 ? 17.643 44.606 2.099 1.00 12.27 ? 236 GLU A O 1 ATOM 1766 C CB . GLU A 1 236 ? 17.073 47.341 0.210 1.00 14.09 ? 236 GLU A CB 1 ATOM 1767 C CG . GLU A 1 236 ? 16.839 46.279 -0.864 1.00 18.45 ? 236 GLU A CG 1 ATOM 1768 C CD . GLU A 1 236 ? 15.347 45.967 -1.084 1.00 21.57 ? 236 GLU A CD 1 ATOM 1769 O OE1 . GLU A 1 236 ? 14.454 46.759 -0.669 1.00 24.77 ? 236 GLU A OE1 1 ATOM 1770 O OE2 . GLU A 1 236 ? 15.089 44.915 -1.687 1.00 25.37 ? 236 GLU A OE2 1 ATOM 1771 N N . LEU A 1 237 ? 19.198 46.204 2.153 1.00 10.19 ? 237 LEU A N 1 ATOM 1772 C CA . LEU A 1 237 ? 20.224 45.199 2.414 1.00 10.78 ? 237 LEU A CA 1 ATOM 1773 C C . LEU A 1 237 ? 20.045 44.691 3.854 1.00 10.21 ? 237 LEU A C 1 ATOM 1774 O O . LEU A 1 237 ? 20.285 43.490 4.103 1.00 10.84 ? 237 LEU A O 1 ATOM 1775 C CB . LEU A 1 237 ? 21.620 45.803 2.217 1.00 10.24 ? 237 LEU A CB 1 ATOM 1776 C CG . LEU A 1 237 ? 21.953 46.268 0.779 1.00 9.82 ? 237 LEU A CG 1 ATOM 1777 C CD1 . LEU A 1 237 ? 23.388 46.846 0.797 1.00 11.88 ? 237 LEU A CD1 1 ATOM 1778 C CD2 . LEU A 1 237 ? 21.906 45.103 -0.241 1.00 11.94 ? 237 LEU A CD2 1 ATOM 1779 N N . ALA A 1 238 ? 19.616 45.548 4.793 1.00 10.10 ? 238 ALA A N 1 ATOM 1780 C CA . ALA A 1 238 ? 19.419 45.060 6.154 1.00 10.29 ? 238 ALA A CA 1 ATOM 1781 C C . ALA A 1 238 ? 18.338 43.965 6.184 1.00 11.28 ? 238 ALA A C 1 ATOM 1782 O O . ALA A 1 238 ? 18.501 42.963 6.917 1.00 11.77 ? 238 ALA A O 1 ATOM 1783 C CB . ALA A 1 238 ? 19.031 46.223 7.077 1.00 11.01 ? 238 ALA A CB 1 ATOM 1784 N N . GLN A 1 239 ? 17.254 44.197 5.440 1.00 11.49 ? 239 GLN A N 1 ATOM 1785 C CA . GLN A 1 239 ? 16.181 43.179 5.427 1.00 13.25 ? 239 GLN A CA 1 ATOM 1786 C C . GLN A 1 239 ? 16.661 41.815 4.952 1.00 14.05 ? 239 GLN A C 1 ATOM 1787 O O . GLN A 1 239 ? 16.134 40.786 5.384 1.00 16.18 ? 239 GLN A O 1 ATOM 1788 C CB . GLN A 1 239 ? 15.027 43.667 4.574 1.00 15.08 ? 239 GLN A CB 1 ATOM 1789 C CG . GLN A 1 239 ? 14.229 44.764 5.271 1.00 18.49 ? 239 GLN A CG 1 ATOM 1790 C CD . GLN A 1 239 ? 13.211 45.461 4.375 1.00 21.87 ? 239 GLN A CD 1 ATOM 1791 O OE1 . GLN A 1 239 ? 13.338 45.510 3.142 1.00 24.52 ? 239 GLN A OE1 1 ATOM 1792 N NE2 . GLN A 1 239 ? 12.205 46.053 5.010 1.00 23.91 ? 239 GLN A NE2 1 ATOM 1793 N N . GLN A 1 240 ? 17.654 41.769 4.073 1.00 12.54 ? 240 GLN A N 1 ATOM 1794 C CA . GLN A 1 240 ? 18.172 40.505 3.561 1.00 12.76 ? 240 GLN A CA 1 ATOM 1795 C C . GLN A 1 240 ? 19.467 40.076 4.227 1.00 11.33 ? 240 GLN A C 1 ATOM 1796 O O . GLN A 1 240 ? 20.077 39.118 3.816 1.00 11.36 ? 240 GLN A O 1 ATOM 1797 C CB . GLN A 1 240 ? 18.437 40.645 2.059 1.00 14.21 ? 240 GLN A CB 1 ATOM 1798 C CG . GLN A 1 240 ? 17.262 41.178 1.232 1.00 17.32 ? 240 GLN A CG 1 ATOM 1799 C CD . GLN A 1 240 ? 16.061 40.325 1.396 1.00 19.74 ? 240 GLN A CD 1 ATOM 1800 O OE1 . GLN A 1 240 ? 14.922 40.836 1.484 1.00 23.80 ? 240 GLN A OE1 1 ATOM 1801 N NE2 . GLN A 1 240 ? 16.273 39.034 1.450 1.00 20.63 ? 240 GLN A NE2 1 ATOM 1802 N N . ARG A 1 241 ? 19.851 40.789 5.303 1.00 11.48 ? 241 ARG A N 1 ATOM 1803 C CA . ARG A 1 241 ? 21.146 40.541 5.955 1.00 10.93 ? 241 ARG A CA 1 ATOM 1804 C C . ARG A 1 241 ? 22.280 40.515 4.921 1.00 9.99 ? 241 ARG A C 1 ATOM 1805 O O . ARG A 1 241 ? 23.124 39.638 4.895 1.00 10.37 ? 241 ARG A O 1 ATOM 1806 C CB . ARG A 1 241 ? 21.171 39.250 6.796 1.00 11.94 ? 241 ARG A CB 1 ATOM 1807 C CG . ARG A 1 241 ? 20.139 39.367 7.911 1.00 13.71 ? 241 ARG A CG 1 ATOM 1808 C CD . ARG A 1 241 ? 20.293 38.225 8.920 1.00 16.13 ? 241 ARG A CD 1 ATOM 1809 N NE . ARG A 1 241 ? 20.237 36.932 8.281 1.00 21.51 ? 241 ARG A NE 1 ATOM 1810 C CZ . ARG A 1 241 ? 20.633 35.817 8.885 1.00 23.06 ? 241 ARG A CZ 1 ATOM 1811 N NH1 . ARG A 1 241 ? 21.090 35.888 10.132 1.00 23.32 ? 241 ARG A NH1 1 ATOM 1812 N NH2 . ARG A 1 241 ? 20.624 34.657 8.223 1.00 24.54 ? 241 ARG A NH2 1 ATOM 1813 N N . GLN A 1 242 ? 22.263 41.548 4.055 1.00 10.18 ? 242 GLN A N 1 ATOM 1814 C CA . GLN A 1 242 ? 23.290 41.703 3.010 1.00 9.85 ? 242 GLN A CA 1 ATOM 1815 C C . GLN A 1 242 ? 24.147 42.949 3.259 1.00 9.81 ? 242 GLN A C 1 ATOM 1816 O O . GLN A 1 242 ? 24.708 43.522 2.318 1.00 10.43 ? 242 GLN A O 1 ATOM 1817 C CB . GLN A 1 242 ? 22.654 41.750 1.622 1.00 10.20 ? 242 GLN A CB 1 ATOM 1818 C CG . GLN A 1 242 ? 22.030 40.362 1.239 1.00 11.68 ? 242 GLN A CG 1 ATOM 1819 C CD . GLN A 1 242 ? 21.203 40.465 -0.031 1.00 12.31 ? 242 GLN A CD 1 ATOM 1820 O OE1 . GLN A 1 242 ? 20.644 41.515 -0.326 1.00 12.38 ? 242 GLN A OE1 1 ATOM 1821 N NE2 . GLN A 1 242 ? 21.158 39.367 -0.794 1.00 13.50 ? 242 GLN A NE2 1 ATOM 1822 N N . LEU A 1 243 ? 24.282 43.336 4.545 1.00 9.19 ? 243 LEU A N 1 ATOM 1823 C CA . LEU A 1 243 ? 25.101 44.504 4.891 1.00 8.67 ? 243 LEU A CA 1 ATOM 1824 C C . LEU A 1 243 ? 26.580 44.138 4.904 1.00 8.89 ? 243 LEU A C 1 ATOM 1825 O O . LEU A 1 243 ? 27.409 45.027 4.925 1.00 9.23 ? 243 LEU A O 1 ATOM 1826 C CB . LEU A 1 243 ? 24.668 45.067 6.247 1.00 9.16 ? 243 LEU A CB 1 ATOM 1827 C CG . LEU A 1 243 ? 23.284 45.751 6.224 1.00 10.54 ? 243 LEU A CG 1 ATOM 1828 C CD1 . LEU A 1 243 ? 22.848 45.963 7.677 1.00 10.96 ? 243 LEU A CD1 1 ATOM 1829 C CD2 . LEU A 1 243 ? 23.317 47.120 5.470 1.00 10.97 ? 243 LEU A CD2 1 ATOM 1830 N N . GLU A 1 244 ? 26.928 42.855 4.999 1.00 8.14 ? 244 GLU A N 1 ATOM 1831 C CA . GLU A 1 244 ? 28.315 42.411 4.866 1.00 8.30 ? 244 GLU A CA 1 ATOM 1832 C C . GLU A 1 244 ? 28.327 41.610 3.579 1.00 8.87 ? 244 GLU A C 1 ATOM 1833 O O . GLU A 1 244 ? 27.514 40.693 3.397 1.00 9.25 ? 244 GLU A O 1 ATOM 1834 C CB . GLU A 1 244 ? 28.783 41.550 6.059 1.00 8.14 ? 244 GLU A CB 1 ATOM 1835 C CG . GLU A 1 244 ? 29.088 42.488 7.250 1.00 9.63 ? 244 GLU A CG 1 ATOM 1836 C CD . GLU A 1 244 ? 29.390 41.805 8.566 1.00 9.12 ? 244 GLU A CD 1 ATOM 1837 O OE1 . GLU A 1 244 ? 28.811 40.725 8.846 1.00 9.74 ? 244 GLU A OE1 1 ATOM 1838 O OE2 . GLU A 1 244 ? 30.198 42.369 9.327 1.00 9.20 ? 244 GLU A OE2 1 ATOM 1839 N N . PHE A 1 245 ? 29.282 41.907 2.691 1.00 8.38 ? 245 PHE A N 1 ATOM 1840 C CA . PHE A 1 245 ? 29.314 41.289 1.371 1.00 7.99 ? 245 PHE A CA 1 ATOM 1841 C C . PHE A 1 245 ? 30.717 41.252 0.817 1.00 8.42 ? 245 PHE A C 1 ATOM 1842 O O . PHE A 1 245 ? 31.601 42.006 1.257 1.00 8.72 ? 245 PHE A O 1 ATOM 1843 C CB . PHE A 1 245 ? 28.366 42.074 0.416 1.00 8.38 ? 245 PHE A CB 1 ATOM 1844 C CG . PHE A 1 245 ? 28.529 43.546 0.473 1.00 7.99 ? 245 PHE A CG 1 ATOM 1845 C CD1 . PHE A 1 245 ? 29.472 44.193 -0.338 1.00 8.48 ? 245 PHE A CD1 1 ATOM 1846 C CD2 . PHE A 1 245 ? 27.720 44.298 1.316 1.00 8.82 ? 245 PHE A CD2 1 ATOM 1847 C CE1 . PHE A 1 245 ? 29.617 45.622 -0.335 1.00 8.27 ? 245 PHE A CE1 1 ATOM 1848 C CE2 . PHE A 1 245 ? 27.848 45.726 1.360 1.00 8.82 ? 245 PHE A CE2 1 ATOM 1849 C CZ . PHE A 1 245 ? 28.816 46.367 0.505 1.00 8.35 ? 245 PHE A CZ 1 ATOM 1850 N N . LEU A 1 246 ? 30.940 40.398 -0.169 1.00 8.01 ? 246 LEU A N 1 ATOM 1851 C CA . LEU A 1 246 ? 32.216 40.328 -0.882 1.00 8.14 ? 246 LEU A CA 1 ATOM 1852 C C . LEU A 1 246 ? 32.045 41.248 -2.083 1.00 7.74 ? 246 LEU A C 1 ATOM 1853 O O . LEU A 1 246 ? 31.381 40.920 -3.089 1.00 8.34 ? 246 LEU A O 1 ATOM 1854 C CB . LEU A 1 246 ? 32.505 38.862 -1.300 1.00 9.55 ? 246 LEU A CB 1 ATOM 1855 C CG . LEU A 1 246 ? 32.818 38.029 -0.033 1.00 12.22 ? 246 LEU A CG 1 ATOM 1856 C CD1 . LEU A 1 246 ? 32.666 36.534 -0.372 1.00 15.68 ? 246 LEU A CD1 1 ATOM 1857 C CD2 . LEU A 1 246 ? 34.261 38.333 0.378 1.00 15.63 ? 246 LEU A CD2 1 ATOM 1858 N N . TRP A 1 247 ? 32.668 42.415 -1.992 1.00 8.06 ? 247 TRP A N 1 ATOM 1859 C CA . TRP A 1 247 ? 32.494 43.454 -3.027 1.00 7.85 ? 247 TRP A CA 1 ATOM 1860 C C . TRP A 1 247 ? 33.524 43.262 -4.121 1.00 7.40 ? 247 TRP A C 1 ATOM 1861 O O . TRP A 1 247 ? 34.725 43.459 -3.903 1.00 7.67 ? 247 TRP A O 1 ATOM 1862 C CB . TRP A 1 247 ? 32.634 44.815 -2.325 1.00 7.37 ? 247 TRP A CB 1 ATOM 1863 C CG . TRP A 1 247 ? 32.212 46.003 -3.180 1.00 5.99 ? 247 TRP A CG 1 ATOM 1864 C CD1 . TRP A 1 247 ? 31.673 45.991 -4.426 1.00 6.79 ? 247 TRP A CD1 1 ATOM 1865 C CD2 . TRP A 1 247 ? 32.220 47.366 -2.757 1.00 7.40 ? 247 TRP A CD2 1 ATOM 1866 N NE1 . TRP A 1 247 ? 31.310 47.299 -4.816 1.00 6.86 ? 247 TRP A NE1 1 ATOM 1867 C CE2 . TRP A 1 247 ? 31.640 48.147 -3.800 1.00 6.63 ? 247 TRP A CE2 1 ATOM 1868 C CE3 . TRP A 1 247 ? 32.664 48.016 -1.598 1.00 7.81 ? 247 TRP A CE3 1 ATOM 1869 C CZ2 . TRP A 1 247 ? 31.506 49.527 -3.712 1.00 7.85 ? 247 TRP A CZ2 1 ATOM 1870 C CZ3 . TRP A 1 247 ? 32.528 49.390 -1.522 1.00 6.84 ? 247 TRP A CZ3 1 ATOM 1871 C CH2 . TRP A 1 247 ? 31.966 50.135 -2.553 1.00 6.93 ? 247 TRP A CH2 1 ATOM 1872 N N . ARG A 1 248 ? 33.028 42.829 -5.297 1.00 7.98 ? 248 ARG A N 1 ATOM 1873 C CA . ARG A 1 248 ? 33.910 42.668 -6.459 1.00 7.87 ? 248 ARG A CA 1 ATOM 1874 C C . ARG A 1 248 ? 33.623 43.739 -7.489 1.00 6.37 ? 248 ARG A C 1 ATOM 1875 O O . ARG A 1 248 ? 32.591 44.388 -7.453 1.00 7.55 ? 248 ARG A O 1 ATOM 1876 C CB . ARG A 1 248 ? 33.686 41.287 -7.128 1.00 8.22 ? 248 ARG A CB 1 ATOM 1877 C CG . ARG A 1 248 ? 32.298 41.123 -7.754 1.00 8.94 ? 248 ARG A CG 1 ATOM 1878 C CD . ARG A 1 248 ? 32.254 39.809 -8.582 1.00 10.80 ? 248 ARG A CD 1 ATOM 1879 N NE . ARG A 1 248 ? 32.299 38.654 -7.697 1.00 11.02 ? 248 ARG A NE 1 ATOM 1880 C CZ . ARG A 1 248 ? 32.247 37.402 -8.129 1.00 12.26 ? 248 ARG A CZ 1 ATOM 1881 N NH1 . ARG A 1 248 ? 32.194 37.165 -9.444 1.00 13.37 ? 248 ARG A NH1 1 ATOM 1882 N NH2 . ARG A 1 248 ? 32.172 36.419 -7.247 1.00 13.35 ? 248 ARG A NH2 1 ATOM 1883 N N . GLN A 1 249 ? 34.551 43.855 -8.445 1.00 7.53 ? 249 GLN A N 1 ATOM 1884 C CA . GLN A 1 249 ? 34.356 44.852 -9.516 1.00 7.75 ? 249 GLN A CA 1 ATOM 1885 C C . GLN A 1 249 ? 33.242 44.394 -10.471 1.00 7.88 ? 249 GLN A C 1 ATOM 1886 O O . GLN A 1 249 ? 32.990 43.184 -10.644 1.00 8.60 ? 249 GLN A O 1 ATOM 1887 C CB . GLN A 1 249 ? 35.686 45.034 -10.289 1.00 8.41 ? 249 GLN A CB 1 ATOM 1888 C CG . GLN A 1 249 ? 36.823 45.536 -9.337 1.00 8.20 ? 249 GLN A CG 1 ATOM 1889 C CD . GLN A 1 249 ? 36.420 46.836 -8.612 1.00 7.93 ? 249 GLN A CD 1 ATOM 1890 O OE1 . GLN A 1 249 ? 36.402 46.893 -7.333 1.00 9.68 ? 249 GLN A OE1 1 ATOM 1891 N NE2 . GLN A 1 249 ? 36.074 47.846 -9.348 1.00 6.94 ? 249 GLN A NE2 1 ATOM 1892 N N . ILE A 1 250 ? 32.594 45.368 -11.108 1.00 8.43 ? 250 ILE A N 1 ATOM 1893 C CA . ILE A 1 250 ? 31.465 45.078 -11.982 1.00 8.84 ? 250 ILE A CA 1 ATOM 1894 C C . ILE A 1 250 ? 31.776 44.140 -13.154 1.00 9.11 ? 250 ILE A C 1 ATOM 1895 O O . ILE A 1 250 ? 30.849 43.483 -13.616 1.00 10.41 ? 250 ILE A O 1 ATOM 1896 C CB . ILE A 1 250 ? 30.766 46.395 -12.508 1.00 9.28 ? 250 ILE A CB 1 ATOM 1897 C CG1 . ILE A 1 250 ? 31.769 47.276 -13.230 1.00 9.96 ? 250 ILE A CG1 1 ATOM 1898 C CG2 . ILE A 1 250 ? 30.073 47.121 -11.352 1.00 10.55 ? 250 ILE A CG2 1 ATOM 1899 C CD1 . ILE A 1 250 ? 31.125 48.598 -13.745 1.00 12.23 ? 250 ILE A CD1 1 ATOM 1900 N N . TRP A 1 251 ? 33.025 44.080 -13.592 1.00 9.91 ? 251 TRP A N 1 ATOM 1901 C CA . TRP A 1 251 ? 33.378 43.212 -14.739 1.00 11.63 ? 251 TRP A CA 1 ATOM 1902 C C . TRP A 1 251 ? 34.017 41.921 -14.305 1.00 13.89 ? 251 TRP A C 1 ATOM 1903 O O . TRP A 1 251 ? 34.331 41.093 -15.147 1.00 14.38 ? 251 TRP A O 1 ATOM 1904 C CB . TRP A 1 251 ? 34.375 43.939 -15.635 1.00 12.48 ? 251 TRP A CB 1 ATOM 1905 C CG . TRP A 1 251 ? 35.613 44.092 -14.938 1.00 14.72 ? 251 TRP A CG 1 ATOM 1906 C CD1 . TRP A 1 251 ? 36.588 43.124 -14.741 1.00 16.07 ? 251 TRP A CD1 1 ATOM 1907 C CD2 . TRP A 1 251 ? 36.028 45.225 -14.252 1.00 14.58 ? 251 TRP A CD2 1 ATOM 1908 N NE1 . TRP A 1 251 ? 37.568 43.616 -13.966 1.00 15.23 ? 251 TRP A NE1 1 ATOM 1909 C CE2 . TRP A 1 251 ? 37.268 44.911 -13.640 1.00 13.94 ? 251 TRP A CE2 1 ATOM 1910 C CE3 . TRP A 1 251 ? 35.487 46.480 -14.064 1.00 13.63 ? 251 TRP A CE3 1 ATOM 1911 C CZ2 . TRP A 1 251 ? 37.976 45.811 -12.856 1.00 14.49 ? 251 TRP A CZ2 1 ATOM 1912 C CZ3 . TRP A 1 251 ? 36.178 47.395 -13.263 1.00 15.34 ? 251 TRP A CZ3 1 ATOM 1913 C CH2 . TRP A 1 251 ? 37.412 47.053 -12.676 1.00 16.28 ? 251 TRP A CH2 1 ATOM 1914 N N . ASP A 1 252 ? 34.163 41.691 -13.003 1.00 12.88 ? 252 ASP A N 1 ATOM 1915 C CA . ASP A 1 252 ? 34.901 40.524 -12.497 1.00 13.76 ? 252 ASP A CA 1 ATOM 1916 C C . ASP A 1 252 ? 34.075 39.256 -12.379 1.00 13.73 ? 252 ASP A C 1 ATOM 1917 O O . ASP A 1 252 ? 33.343 39.021 -11.450 1.00 14.07 ? 252 ASP A O 1 ATOM 1918 C CB . ASP A 1 252 ? 35.542 40.942 -11.160 1.00 13.45 ? 252 ASP A CB 1 ATOM 1919 C CG . ASP A 1 252 ? 36.282 39.815 -10.499 1.00 15.81 ? 252 ASP A CG 1 ATOM 1920 O OD1 . ASP A 1 252 ? 36.547 38.796 -11.191 1.00 17.56 ? 252 ASP A OD1 1 ATOM 1921 O OD2 . ASP A 1 252 ? 36.574 39.960 -9.295 1.00 13.57 ? 252 ASP A OD2 1 ATOM 1922 N N . ASN A 1 253 ? 34.220 38.396 -13.377 1.00 15.04 ? 253 ASN A N 1 ATOM 1923 C CA . ASN A 1 253 ? 33.451 37.194 -13.446 1.00 15.45 ? 253 ASN A CA 1 ATOM 1924 C C . ASN A 1 253 ? 33.852 36.149 -12.411 1.00 15.54 ? 253 ASN A C 1 ATOM 1925 O O . ASN A 1 253 ? 33.003 35.492 -11.834 1.00 16.88 ? 253 ASN A O 1 ATOM 1926 C CB . ASN A 1 253 ? 33.647 36.598 -14.840 1.00 18.46 ? 253 ASN A CB 1 ATOM 1927 C CG . ASN A 1 253 ? 32.841 35.386 -15.048 1.00 21.46 ? 253 ASN A CG 1 ATOM 1928 O OD1 . ASN A 1 253 ? 33.383 34.345 -15.482 1.00 24.92 ? 253 ASN A OD1 1 ATOM 1929 N ND2 . ASN A 1 253 ? 31.548 35.462 -14.765 1.00 20.73 ? 253 ASN A ND2 1 ATOM 1930 N N . LYS A 1 254 ? 35.140 36.063 -12.184 1.00 18.16 ? 254 LYS A N 1 ATOM 1931 C CA . LYS A 1 254 ? 35.725 35.066 -11.278 1.00 19.39 ? 254 LYS A CA 1 ATOM 1932 C C . LYS A 1 254 ? 35.637 35.422 -9.801 1.00 19.31 ? 254 LYS A C 1 ATOM 1933 O O . LYS A 1 254 ? 35.438 34.547 -8.945 1.00 20.52 ? 254 LYS A O 1 ATOM 1934 C CB . LYS A 1 254 ? 37.192 34.875 -11.668 1.00 23.08 ? 254 LYS A CB 1 ATOM 1935 C CG . LYS A 1 254 ? 37.829 33.615 -11.157 1.00 26.56 ? 254 LYS A CG 1 ATOM 1936 C CD . LYS A 1 254 ? 39.250 33.489 -11.724 1.00 28.96 ? 254 LYS A CD 1 ATOM 1937 C CE . LYS A 1 254 ? 40.056 32.360 -11.047 1.00 29.92 ? 254 LYS A CE 1 ATOM 1938 N NZ . LYS A 1 254 ? 40.033 32.382 -9.545 1.00 31.35 ? 254 LYS A NZ 1 ATOM 1939 N N . GLY A 1 255 ? 35.787 36.709 -9.519 1.00 17.48 ? 255 GLY A N 1 ATOM 1940 C CA . GLY A 1 255 ? 35.741 37.183 -8.146 1.00 15.81 ? 255 GLY A CA 1 ATOM 1941 C C . GLY A 1 255 ? 37.103 37.442 -7.503 1.00 15.46 ? 255 GLY A C 1 ATOM 1942 O O . GLY A 1 255 ? 37.134 37.701 -6.307 1.00 14.80 ? 255 GLY A O 1 ATOM 1943 N N . ASP A 1 256 ? 38.205 37.426 -8.243 1.00 15.26 ? 256 ASP A N 1 ATOM 1944 C CA . ASP A 1 256 ? 39.502 37.655 -7.611 1.00 16.23 ? 256 ASP A CA 1 ATOM 1945 C C . ASP A 1 256 ? 39.698 39.065 -7.069 1.00 14.63 ? 256 ASP A C 1 ATOM 1946 O O . ASP A 1 256 ? 40.602 39.304 -6.265 1.00 15.04 ? 256 ASP A O 1 ATOM 1947 C CB . ASP A 1 256 ? 40.659 37.338 -8.567 1.00 18.82 ? 256 ASP A CB 1 ATOM 1948 C CG A ASP A 1 256 ? 40.667 35.893 -9.023 0.50 20.65 ? 256 ASP A CG 1 ATOM 1949 C CG B ASP A 1 256 ? 40.147 37.362 -10.107 0.50 20.80 ? 256 ASP A CG 1 ATOM 1950 O OD1 A ASP A 1 256 ? 40.167 35.024 -8.280 0.50 22.41 ? 256 ASP A OD1 1 ATOM 1951 O OD1 B ASP A 1 256 ? 39.567 38.370 -10.552 0.50 21.58 ? 256 ASP A OD1 1 ATOM 1952 O OD2 A ASP A 1 256 ? 41.197 35.643 -10.123 0.50 21.95 ? 256 ASP A OD2 1 ATOM 1953 O OD2 B ASP A 1 256 ? 40.368 36.344 -10.804 0.50 23.20 ? 256 ASP A OD2 1 ATOM 1954 N N . THR A 1 257 ? 38.862 40.010 -7.495 1.00 12.89 ? 257 THR A N 1 ATOM 1955 C CA . THR A 1 257 ? 38.996 41.363 -6.963 1.00 11.88 ? 257 THR A CA 1 ATOM 1956 C C . THR A 1 257 ? 38.189 41.552 -5.666 1.00 11.30 ? 257 THR A C 1 ATOM 1957 O O . THR A 1 257 ? 38.294 42.630 -5.045 1.00 11.26 ? 257 THR A O 1 ATOM 1958 C CB . THR A 1 257 ? 38.459 42.460 -7.935 1.00 11.30 ? 257 THR A CB 1 ATOM 1959 O OG1 . THR A 1 257 ? 37.039 42.268 -8.149 1.00 10.96 ? 257 THR A OG1 1 ATOM 1960 C CG2 . THR A 1 257 ? 39.222 42.342 -9.274 1.00 13.46 ? 257 THR A CG2 1 ATOM 1961 N N . ALA A 1 258 ? 37.435 40.527 -5.239 1.00 11.06 ? 258 ALA A N 1 ATOM 1962 C CA . ALA A 1 258 ? 36.565 40.671 -4.063 1.00 10.67 ? 258 ALA A CA 1 ATOM 1963 C C . ALA A 1 258 ? 37.244 41.057 -2.790 1.00 9.62 ? 258 ALA A C 1 ATOM 1964 O O . ALA A 1 258 ? 38.323 40.568 -2.469 1.00 10.73 ? 258 ALA A O 1 ATOM 1965 C CB . ALA A 1 258 ? 35.795 39.395 -3.756 1.00 12.01 ? 258 ALA A CB 1 ATOM 1966 N N . LEU A 1 259 ? 36.604 41.968 -2.078 1.00 8.15 ? 259 LEU A N 1 ATOM 1967 C CA . LEU A 1 259 ? 37.079 42.395 -0.747 1.00 7.79 ? 259 LEU A CA 1 ATOM 1968 C C . LEU A 1 259 ? 35.887 42.390 0.207 1.00 7.40 ? 259 LEU A C 1 ATOM 1969 O O . LEU A 1 259 ? 34.842 43.019 -0.062 1.00 7.37 ? 259 LEU A O 1 ATOM 1970 C CB . LEU A 1 259 ? 37.681 43.814 -0.814 1.00 9.16 ? 259 LEU A CB 1 ATOM 1971 C CG . LEU A 1 259 ? 38.424 44.234 0.470 1.00 8.32 ? 259 LEU A CG 1 ATOM 1972 C CD1 . LEU A 1 259 ? 39.697 43.343 0.725 1.00 10.05 ? 259 LEU A CD1 1 ATOM 1973 C CD2 . LEU A 1 259 ? 38.877 45.721 0.287 1.00 9.65 ? 259 LEU A CD2 1 ATOM 1974 N N . PHE A 1 260 ? 36.040 41.738 1.363 1.00 7.57 ? 260 PHE A N 1 ATOM 1975 C CA . PHE A 1 260 ? 34.962 41.697 2.335 1.00 7.31 ? 260 PHE A CA 1 ATOM 1976 C C . PHE A 1 260 ? 34.656 43.112 2.819 1.00 7.24 ? 260 PHE A C 1 ATOM 1977 O O . PHE A 1 260 ? 35.588 43.852 3.247 1.00 7.65 ? 260 PHE A O 1 ATOM 1978 C CB . PHE A 1 260 ? 35.404 40.811 3.519 1.00 8.03 ? 260 PHE A CB 1 ATOM 1979 C CG . PHE A 1 260 ? 34.298 40.640 4.546 1.00 8.89 ? 260 PHE A CG 1 ATOM 1980 C CD1 . PHE A 1 260 ? 33.309 39.666 4.333 1.00 10.01 ? 260 PHE A CD1 1 ATOM 1981 C CD2 . PHE A 1 260 ? 34.227 41.424 5.682 1.00 8.65 ? 260 PHE A CD2 1 ATOM 1982 C CE1 . PHE A 1 260 ? 32.253 39.481 5.283 1.00 11.24 ? 260 PHE A CE1 1 ATOM 1983 C CE2 . PHE A 1 260 ? 33.188 41.263 6.630 1.00 10.36 ? 260 PHE A CE2 1 ATOM 1984 C CZ . PHE A 1 260 ? 32.219 40.303 6.435 1.00 11.04 ? 260 PHE A CZ 1 ATOM 1985 N N . THR A 1 261 ? 33.378 43.479 2.813 1.00 6.72 ? 261 THR A N 1 ATOM 1986 C CA . THR A 1 261 ? 32.965 44.833 3.130 1.00 7.29 ? 261 THR A CA 1 ATOM 1987 C C . THR A 1 261 ? 31.846 44.787 4.146 1.00 7.06 ? 261 THR A C 1 ATOM 1988 O O . THR A 1 261 ? 30.899 43.996 4.028 1.00 8.07 ? 261 THR A O 1 ATOM 1989 C CB . THR A 1 261 ? 32.441 45.544 1.844 1.00 8.16 ? 261 THR A CB 1 ATOM 1990 O OG1 . THR A 1 261 ? 33.516 45.587 0.885 1.00 8.06 ? 261 THR A OG1 1 ATOM 1991 C CG2 . THR A 1 261 ? 31.932 46.956 2.144 1.00 8.39 ? 261 THR A CG2 1 ATOM 1992 N N . HIS A 1 262 ? 31.955 45.650 5.154 1.00 7.15 ? 262 HIS A N 1 ATOM 1993 C CA . HIS A 1 262 ? 30.902 45.837 6.150 1.00 7.31 ? 262 HIS A CA 1 ATOM 1994 C C . HIS A 1 262 ? 30.253 47.192 5.958 1.00 7.51 ? 262 HIS A C 1 ATOM 1995 O O . HIS A 1 262 ? 30.956 48.226 6.060 1.00 7.84 ? 262 HIS A O 1 ATOM 1996 C CB . HIS A 1 262 ? 31.528 45.788 7.564 1.00 7.71 ? 262 HIS A CB 1 ATOM 1997 C CG . HIS A 1 262 ? 30.569 46.148 8.674 1.00 7.05 ? 262 HIS A CG 1 ATOM 1998 N ND1 . HIS A 1 262 ? 29.934 45.185 9.442 1.00 7.98 ? 262 HIS A ND1 1 ATOM 1999 C CD2 . HIS A 1 262 ? 30.141 47.354 9.146 1.00 7.83 ? 262 HIS A CD2 1 ATOM 2000 C CE1 . HIS A 1 262 ? 29.167 45.803 10.351 1.00 9.03 ? 262 HIS A CE1 1 ATOM 2001 N NE2 . HIS A 1 262 ? 29.265 47.108 10.189 1.00 8.68 ? 262 HIS A NE2 1 ATOM 2002 N N . MET A 1 263 ? 28.950 47.240 5.679 1.00 7.19 ? 263 MET A N 1 ATOM 2003 C CA . MET A 1 263 ? 28.250 48.509 5.614 1.00 7.17 ? 263 MET A CA 1 ATOM 2004 C C . MET A 1 263 ? 27.504 48.708 6.939 1.00 7.71 ? 263 MET A C 1 ATOM 2005 O O . MET A 1 263 ? 26.733 47.795 7.369 1.00 8.50 ? 263 MET A O 1 ATOM 2006 C CB . MET A 1 263 ? 27.216 48.468 4.476 1.00 8.03 ? 263 MET A CB 1 ATOM 2007 C CG . MET A 1 263 ? 26.420 49.777 4.329 1.00 8.53 ? 263 MET A CG 1 ATOM 2008 S SD . MET A 1 263 ? 25.039 49.585 3.110 1.00 8.69 ? 263 MET A SD 1 ATOM 2009 C CE . MET A 1 263 ? 25.917 49.150 1.579 1.00 10.51 ? 263 MET A CE 1 ATOM 2010 N N . MET A 1 264 ? 27.721 49.850 7.584 1.00 7.44 ? 264 MET A N 1 ATOM 2011 C CA . MET A 1 264 ? 27.022 50.142 8.842 1.00 8.43 ? 264 MET A CA 1 ATOM 2012 C C . MET A 1 264 ? 25.553 50.371 8.440 1.00 8.42 ? 264 MET A C 1 ATOM 2013 O O . MET A 1 264 ? 25.244 50.835 7.323 1.00 8.76 ? 264 MET A O 1 ATOM 2014 C CB . MET A 1 264 ? 27.694 51.292 9.581 1.00 8.53 ? 264 MET A CB 1 ATOM 2015 C CG A MET A 1 264 ? 29.045 51.132 9.936 0.50 7.86 ? 264 MET A CG 1 ATOM 2016 C CG B MET A 1 264 ? 29.140 50.888 9.943 0.50 9.16 ? 264 MET A CG 1 ATOM 2017 S SD A MET A 1 264 ? 30.066 52.598 10.387 0.50 7.76 ? 264 MET A SD 1 ATOM 2018 S SD B MET A 1 264 ? 29.737 51.596 11.486 0.50 11.33 ? 264 MET A SD 1 ATOM 2019 C CE A MET A 1 264 ? 28.962 53.515 11.546 0.50 10.44 ? 264 MET A CE 1 ATOM 2020 C CE B MET A 1 264 ? 29.483 53.366 11.075 0.50 10.79 ? 264 MET A CE 1 ATOM 2021 N N . PRO A 1 265 ? 24.613 50.079 9.349 1.00 8.17 ? 265 PRO A N 1 ATOM 2022 C CA . PRO A 1 265 ? 23.199 50.187 9.034 1.00 8.93 ? 265 PRO A CA 1 ATOM 2023 C C . PRO A 1 265 ? 22.357 51.378 9.203 1.00 8.74 ? 265 PRO A C 1 ATOM 2024 O O . PRO A 1 265 ? 21.264 51.463 8.635 1.00 9.47 ? 265 PRO A O 1 ATOM 2025 C CB . PRO A 1 265 ? 22.556 49.178 9.987 1.00 10.45 ? 265 PRO A CB 1 ATOM 2026 C CG . PRO A 1 265 ? 23.469 49.144 11.165 1.00 10.40 ? 265 PRO A CG 1 ATOM 2027 C CD . PRO A 1 265 ? 24.839 49.472 10.641 1.00 8.10 ? 265 PRO A CD 1 ATOM 2028 N N . PHE A 1 266 ? 22.881 52.299 9.986 1.00 9.08 ? 266 PHE A N 1 ATOM 2029 C CA . PHE A 1 266 ? 22.100 53.432 10.435 1.00 9.61 ? 266 PHE A CA 1 ATOM 2030 C C . PHE A 1 266 ? 22.461 54.768 9.856 1.00 8.73 ? 266 PHE A C 1 ATOM 2031 O O . PHE A 1 266 ? 23.355 54.846 9.011 1.00 9.43 ? 266 PHE A O 1 ATOM 2032 C CB . PHE A 1 266 ? 22.101 53.417 11.979 1.00 10.00 ? 266 PHE A CB 1 ATOM 2033 C CG . PHE A 1 266 ? 21.549 52.111 12.592 1.00 9.51 ? 266 PHE A CG 1 ATOM 2034 C CD1 . PHE A 1 266 ? 20.393 51.480 12.074 1.00 10.14 ? 266 PHE A CD1 1 ATOM 2035 C CD2 . PHE A 1 266 ? 22.184 51.549 13.680 1.00 9.46 ? 266 PHE A CD2 1 ATOM 2036 C CE1 . PHE A 1 266 ? 19.911 50.283 12.674 1.00 10.59 ? 266 PHE A CE1 1 ATOM 2037 C CE2 . PHE A 1 266 ? 21.707 50.356 14.270 1.00 10.40 ? 266 PHE A CE2 1 ATOM 2038 C CZ . PHE A 1 266 ? 20.565 49.739 13.748 1.00 10.00 ? 266 PHE A CZ 1 ATOM 2039 N N . TYR A 1 267 ? 21.802 55.810 10.297 1.00 9.08 ? 267 TYR A N 1 ATOM 2040 C CA . TYR A 1 267 ? 21.909 57.114 9.669 1.00 8.83 ? 267 TYR A CA 1 ATOM 2041 C C . TYR A 1 267 ? 23.241 57.826 9.847 1.00 8.59 ? 267 TYR A C 1 ATOM 2042 O O . TYR A 1 267 ? 23.589 58.668 9.002 1.00 8.41 ? 267 TYR A O 1 ATOM 2043 C CB . TYR A 1 267 ? 20.752 57.956 10.234 1.00 10.19 ? 267 TYR A CB 1 ATOM 2044 C CG . TYR A 1 267 ? 20.842 59.469 10.084 1.00 10.32 ? 267 TYR A CG 1 ATOM 2045 C CD1 . TYR A 1 267 ? 20.515 60.104 8.881 1.00 12.28 ? 267 TYR A CD1 1 ATOM 2046 C CD2 . TYR A 1 267 ? 21.226 60.251 11.171 1.00 12.64 ? 267 TYR A CD2 1 ATOM 2047 C CE1 . TYR A 1 267 ? 20.595 61.517 8.769 1.00 13.44 ? 267 TYR A CE1 1 ATOM 2048 C CE2 . TYR A 1 267 ? 21.291 61.621 11.085 1.00 13.62 ? 267 TYR A CE2 1 ATOM 2049 C CZ . TYR A 1 267 ? 20.978 62.232 9.901 1.00 14.02 ? 267 TYR A CZ 1 ATOM 2050 O OH . TYR A 1 267 ? 21.037 63.630 9.890 1.00 18.28 ? 267 TYR A OH 1 ATOM 2051 N N . SER A 1 268 ? 23.913 57.562 10.937 1.00 8.31 ? 268 SER A N 1 ATOM 2052 C CA . SER A 1 268 ? 25.192 58.239 11.220 1.00 8.89 ? 268 SER A CA 1 ATOM 2053 C C . SER A 1 268 ? 26.177 57.293 11.894 1.00 9.04 ? 268 SER A C 1 ATOM 2054 O O . SER A 1 268 ? 25.832 56.193 12.327 1.00 8.97 ? 268 SER A O 1 ATOM 2055 C CB . SER A 1 268 ? 24.911 59.427 12.146 1.00 9.92 ? 268 SER A CB 1 ATOM 2056 O OG . SER A 1 268 ? 26.119 60.090 12.515 1.00 12.53 ? 268 SER A OG 1 ATOM 2057 N N . TYR A 1 269 ? 27.457 57.682 11.899 1.00 8.83 ? 269 TYR A N 1 ATOM 2058 C CA . TYR A 1 269 ? 28.468 56.979 12.680 1.00 8.18 ? 269 TYR A CA 1 ATOM 2059 C C . TYR A 1 269 ? 28.577 57.523 14.164 1.00 8.55 ? 269 TYR A C 1 ATOM 2060 O O . TYR A 1 269 ? 29.436 57.049 14.918 1.00 9.06 ? 269 TYR A O 1 ATOM 2061 C CB . TYR A 1 269 ? 29.851 57.164 11.993 1.00 7.68 ? 269 TYR A CB 1 ATOM 2062 C CG . TYR A 1 269 ? 30.248 58.616 11.771 1.00 8.52 ? 269 TYR A CG 1 ATOM 2063 C CD1 . TYR A 1 269 ? 30.704 59.429 12.842 1.00 8.88 ? 269 TYR A CD1 1 ATOM 2064 C CD2 . TYR A 1 269 ? 30.158 59.178 10.489 1.00 8.63 ? 269 TYR A CD2 1 ATOM 2065 C CE1 . TYR A 1 269 ? 31.057 60.789 12.614 1.00 9.93 ? 269 TYR A CE1 1 ATOM 2066 C CE2 . TYR A 1 269 ? 30.512 60.522 10.246 1.00 8.86 ? 269 TYR A CE2 1 ATOM 2067 C CZ . TYR A 1 269 ? 30.958 61.302 11.328 1.00 9.32 ? 269 TYR A CZ 1 ATOM 2068 O OH . TYR A 1 269 ? 31.285 62.599 11.101 1.00 9.25 ? 269 TYR A OH 1 ATOM 2069 N N . ASP A 1 270 ? 27.742 58.496 14.553 1.00 8.70 ? 270 ASP A N 1 ATOM 2070 C CA . ASP A 1 270 ? 27.796 59.041 15.918 1.00 9.02 ? 270 ASP A CA 1 ATOM 2071 C C . ASP A 1 270 ? 27.242 58.007 16.904 1.00 8.23 ? 270 ASP A C 1 ATOM 2072 O O . ASP A 1 270 ? 26.712 56.950 16.503 1.00 9.28 ? 270 ASP A O 1 ATOM 2073 C CB . ASP A 1 270 ? 27.124 60.437 15.961 1.00 9.85 ? 270 ASP A CB 1 ATOM 2074 C CG . ASP A 1 270 ? 25.640 60.423 15.757 1.00 10.28 ? 270 ASP A CG 1 ATOM 2075 O OD1 . ASP A 1 270 ? 25.015 59.345 15.710 1.00 11.41 ? 270 ASP A OD1 1 ATOM 2076 O OD2 . ASP A 1 270 ? 25.088 61.557 15.678 1.00 12.94 ? 270 ASP A OD2 1 ATOM 2077 N N . ILE A 1 271 ? 27.458 58.262 18.186 1.00 8.97 ? 271 ILE A N 1 ATOM 2078 C CA . ILE A 1 271 ? 27.053 57.251 19.194 1.00 9.31 ? 271 ILE A CA 1 ATOM 2079 C C . ILE A 1 271 ? 25.553 56.991 19.175 1.00 8.75 ? 271 ILE A C 1 ATOM 2080 O O . ILE A 1 271 ? 25.158 55.814 19.196 1.00 9.20 ? 271 ILE A O 1 ATOM 2081 C CB . ILE A 1 271 ? 27.624 57.631 20.553 1.00 9.43 ? 271 ILE A CB 1 ATOM 2082 C CG1 . ILE A 1 271 ? 29.141 57.499 20.454 1.00 9.69 ? 271 ILE A CG1 1 ATOM 2083 C CG2 . ILE A 1 271 ? 27.058 56.671 21.663 1.00 10.38 ? 271 ILE A CG2 1 ATOM 2084 C CD1 . ILE A 1 271 ? 29.891 58.164 21.634 1.00 9.88 ? 271 ILE A CD1 1 ATOM 2085 N N . PRO A 1 272 ? 24.701 58.021 19.007 1.00 9.00 ? 272 PRO A N 1 ATOM 2086 C CA . PRO A 1 272 ? 23.243 57.722 18.969 1.00 9.89 ? 272 PRO A CA 1 ATOM 2087 C C . PRO A 1 272 ? 22.838 56.792 17.845 1.00 10.63 ? 272 PRO A C 1 ATOM 2088 O O . PRO A 1 272 ? 21.792 56.118 17.942 1.00 11.02 ? 272 PRO A O 1 ATOM 2089 C CB . PRO A 1 272 ? 22.565 59.093 18.798 1.00 10.92 ? 272 PRO A CB 1 ATOM 2090 C CG . PRO A 1 272 ? 23.567 60.032 19.503 1.00 11.01 ? 272 PRO A CG 1 ATOM 2091 C CD . PRO A 1 272 ? 24.959 59.476 19.106 1.00 9.96 ? 272 PRO A CD 1 ATOM 2092 N N . HIS A 1 273 ? 23.650 56.702 16.781 1.00 9.66 ? 273 HIS A N 1 ATOM 2093 C CA . HIS A 1 273 ? 23.274 55.837 15.637 1.00 9.05 ? 273 HIS A CA 1 ATOM 2094 C C . HIS A 1 273 ? 24.201 54.658 15.444 1.00 9.45 ? 273 HIS A C 1 ATOM 2095 O O . HIS A 1 273 ? 24.244 54.050 14.349 1.00 10.07 ? 273 HIS A O 1 ATOM 2096 C CB . HIS A 1 273 ? 23.133 56.666 14.328 1.00 9.33 ? 273 HIS A CB 1 ATOM 2097 C CG . HIS A 1 273 ? 22.137 57.779 14.450 1.00 9.56 ? 273 HIS A CG 1 ATOM 2098 N ND1 . HIS A 1 273 ? 20.787 57.694 14.115 1.00 11.76 ? 273 HIS A ND1 1 ATOM 2099 C CD2 . HIS A 1 273 ? 22.325 59.020 14.948 1.00 8.60 ? 273 HIS A CD2 1 ATOM 2100 C CE1 . HIS A 1 273 ? 20.206 58.849 14.412 1.00 7.91 ? 273 HIS A CE1 1 ATOM 2101 N NE2 . HIS A 1 273 ? 21.108 59.667 14.923 1.00 12.20 ? 273 HIS A NE2 1 ATOM 2102 N N . THR A 1 274 ? 24.922 54.285 16.498 1.00 8.96 ? 274 THR A N 1 ATOM 2103 C CA . THR A 1 274 ? 25.771 53.119 16.405 1.00 9.28 ? 274 THR A CA 1 ATOM 2104 C C . THR A 1 274 ? 25.560 52.026 17.452 1.00 9.11 ? 274 THR A C 1 ATOM 2105 O O . THR A 1 274 ? 26.084 50.952 17.316 1.00 10.36 ? 274 THR A O 1 ATOM 2106 C CB . THR A 1 274 ? 27.275 53.511 16.361 1.00 9.89 ? 274 THR A CB 1 ATOM 2107 O OG1 . THR A 1 274 ? 27.550 54.468 17.397 1.00 9.82 ? 274 THR A OG1 1 ATOM 2108 C CG2 . THR A 1 274 ? 27.644 54.105 14.988 1.00 10.44 ? 274 THR A CG2 1 ATOM 2109 N N . CYS A 1 275 ? 24.779 52.291 18.503 1.00 10.42 ? 275 CYS A N 1 ATOM 2110 C CA . CYS A 1 275 ? 24.584 51.195 19.452 1.00 10.78 ? 275 CYS A CA 1 ATOM 2111 C C . CYS A 1 275 ? 23.408 50.276 19.082 1.00 10.04 ? 275 CYS A C 1 ATOM 2112 O O . CYS A 1 275 ? 23.350 49.135 19.558 1.00 11.82 ? 275 CYS A O 1 ATOM 2113 C CB . CYS A 1 275 ? 24.314 51.781 20.861 1.00 11.70 ? 275 CYS A CB 1 ATOM 2114 S SG . CYS A 1 275 ? 22.582 51.887 21.439 1.00 13.29 ? 275 CYS A SG 1 ATOM 2115 N N . GLY A 1 276 ? 22.534 50.744 18.220 1.00 10.18 ? 276 GLY A N 1 ATOM 2116 C CA . GLY A 1 276 ? 21.310 50.003 17.949 1.00 10.02 ? 276 GLY A CA 1 ATOM 2117 C C . GLY A 1 276 ? 20.390 50.900 17.190 1.00 10.16 ? 276 GLY A C 1 ATOM 2118 O O . GLY A 1 276 ? 20.742 52.056 16.925 1.00 10.97 ? 276 GLY A O 1 ATOM 2119 N N . PRO A 1 277 ? 19.161 50.458 16.882 1.00 10.43 ? 277 PRO A N 1 ATOM 2120 C CA . PRO A 1 277 ? 18.205 51.217 16.113 1.00 11.33 ? 277 PRO A CA 1 ATOM 2121 C C . PRO A 1 277 ? 17.523 52.416 16.702 1.00 10.75 ? 277 PRO A C 1 ATOM 2122 O O . PRO A 1 277 ? 16.953 53.175 15.957 1.00 11.46 ? 277 PRO A O 1 ATOM 2123 C CB . PRO A 1 277 ? 17.169 50.151 15.689 1.00 11.61 ? 277 PRO A CB 1 ATOM 2124 C CG . PRO A 1 277 ? 17.184 49.216 16.954 1.00 11.40 ? 277 PRO A CG 1 ATOM 2125 C CD . PRO A 1 277 ? 18.663 49.105 17.242 1.00 11.31 ? 277 PRO A CD 1 ATOM 2126 N N . ASP A 1 278 ? 17.594 52.557 18.026 1.00 11.21 ? 278 ASP A N 1 ATOM 2127 C CA . ASP A 1 278 ? 16.858 53.664 18.659 1.00 12.39 ? 278 ASP A CA 1 ATOM 2128 C C . ASP A 1 278 ? 17.807 54.713 19.208 1.00 10.94 ? 278 ASP A C 1 ATOM 2129 O O . ASP A 1 278 ? 18.396 54.525 20.275 1.00 12.00 ? 278 ASP A O 1 ATOM 2130 C CB . ASP A 1 278 ? 15.970 53.130 19.805 1.00 13.15 ? 278 ASP A CB 1 ATOM 2131 C CG . ASP A 1 278 ? 15.079 54.219 20.381 1.00 13.90 ? 278 ASP A CG 1 ATOM 2132 O OD1 . ASP A 1 278 ? 15.200 55.413 20.026 1.00 14.69 ? 278 ASP A OD1 1 ATOM 2133 O OD2 . ASP A 1 278 ? 14.211 53.875 21.233 1.00 16.31 ? 278 ASP A OD2 1 ATOM 2134 N N . PRO A 1 279 ? 17.948 55.833 18.476 1.00 11.86 ? 279 PRO A N 1 ATOM 2135 C CA . PRO A 1 279 ? 18.880 56.881 18.955 1.00 12.97 ? 279 PRO A CA 1 ATOM 2136 C C . PRO A 1 279 ? 18.505 57.513 20.280 1.00 13.11 ? 279 PRO A C 1 ATOM 2137 O O . PRO A 1 279 ? 19.379 58.007 20.948 1.00 12.47 ? 279 PRO A O 1 ATOM 2138 C CB . PRO A 1 279 ? 18.923 57.890 17.780 1.00 12.88 ? 279 PRO A CB 1 ATOM 2139 C CG . PRO A 1 279 ? 17.555 57.797 17.205 1.00 12.58 ? 279 PRO A CG 1 ATOM 2140 C CD . PRO A 1 279 ? 17.215 56.270 17.282 1.00 12.11 ? 279 PRO A CD 1 ATOM 2141 N N . LYS A 1 280 ? 17.215 57.500 20.658 1.00 12.51 ? 280 LYS A N 1 ATOM 2142 C CA . LYS A 1 280 ? 16.852 58.061 21.974 1.00 13.98 ? 280 LYS A CA 1 ATOM 2143 C C . LYS A 1 280 ? 17.482 57.228 23.101 1.00 13.32 ? 280 LYS A C 1 ATOM 2144 O O . LYS A 1 280 ? 17.904 57.748 24.158 1.00 14.33 ? 280 LYS A O 1 ATOM 2145 C CB . LYS A 1 280 ? 15.339 58.067 22.118 1.00 15.66 ? 280 LYS A CB 1 ATOM 2146 C CG . LYS A 1 280 ? 14.834 58.507 23.509 1.00 17.37 ? 280 LYS A CG 1 ATOM 2147 C CD . LYS A 1 280 ? 13.297 58.550 23.394 1.00 20.36 ? 280 LYS A CD 1 ATOM 2148 C CE . LYS A 1 280 ? 12.626 59.047 24.670 1.00 24.55 ? 280 LYS A CE 1 ATOM 2149 N NZ . LYS A 1 280 ? 11.192 59.403 24.366 1.00 26.65 ? 280 LYS A NZ 1 ATOM 2150 N N . VAL A 1 281 ? 17.639 55.918 22.877 1.00 12.80 ? 281 VAL A N 1 ATOM 2151 C CA . VAL A 1 281 ? 18.285 55.063 23.849 1.00 13.31 ? 281 VAL A CA 1 ATOM 2152 C C . VAL A 1 281 ? 19.822 55.127 23.717 1.00 12.35 ? 281 VAL A C 1 ATOM 2153 O O . VAL A 1 281 ? 20.566 55.286 24.696 1.00 11.65 ? 281 VAL A O 1 ATOM 2154 C CB . VAL A 1 281 ? 17.859 53.583 23.675 1.00 13.44 ? 281 VAL A CB 1 ATOM 2155 C CG1 . VAL A 1 281 ? 18.699 52.669 24.591 1.00 13.00 ? 281 VAL A CG1 1 ATOM 2156 C CG2 . VAL A 1 281 ? 16.307 53.480 23.909 1.00 13.73 ? 281 VAL A CG2 1 ATOM 2157 N N . CYS A 1 282 ? 20.329 55.045 22.466 1.00 12.10 ? 282 CYS A N 1 ATOM 2158 C CA . CYS A 1 282 ? 21.800 55.043 22.304 1.00 12.62 ? 282 CYS A CA 1 ATOM 2159 C C . CYS A 1 282 ? 22.465 56.332 22.793 1.00 10.60 ? 282 CYS A C 1 ATOM 2160 O O . CYS A 1 282 ? 23.612 56.289 23.297 1.00 11.43 ? 282 CYS A O 1 ATOM 2161 C CB . CYS A 1 282 ? 22.185 54.827 20.829 1.00 12.09 ? 282 CYS A CB 1 ATOM 2162 S SG . CYS A 1 282 ? 21.732 53.215 20.158 1.00 12.64 ? 282 CYS A SG 1 ATOM 2163 N N . CYS A 1 283 ? 21.746 57.452 22.628 1.00 11.21 ? 283 CYS A N 1 ATOM 2164 C CA . CYS A 1 283 ? 22.306 58.716 23.059 1.00 11.58 ? 283 CYS A CA 1 ATOM 2165 C C . CYS A 1 283 ? 22.594 58.698 24.553 1.00 12.06 ? 283 CYS A C 1 ATOM 2166 O O . CYS A 1 283 ? 23.472 59.385 25.007 1.00 11.37 ? 283 CYS A O 1 ATOM 2167 C CB . CYS A 1 283 ? 21.335 59.843 22.683 1.00 11.63 ? 283 CYS A CB 1 ATOM 2168 S SG . CYS A 1 283 ? 22.150 61.479 22.815 1.00 13.00 ? 283 CYS A SG 1 ATOM 2169 N N . GLN A 1 284 ? 21.855 57.869 25.309 1.00 11.82 ? 284 GLN A N 1 ATOM 2170 C CA . GLN A 1 284 ? 22.079 57.781 26.739 1.00 11.44 ? 284 GLN A CA 1 ATOM 2171 C C . GLN A 1 284 ? 23.366 57.025 27.114 1.00 11.77 ? 284 GLN A C 1 ATOM 2172 O O . GLN A 1 284 ? 23.736 56.936 28.277 1.00 13.02 ? 284 GLN A O 1 ATOM 2173 C CB . GLN A 1 284 ? 20.869 57.085 27.419 1.00 12.15 ? 284 GLN A CB 1 ATOM 2174 C CG . GLN A 1 284 ? 19.593 57.844 27.254 1.00 14.26 ? 284 GLN A CG 1 ATOM 2175 C CD . GLN A 1 284 ? 18.419 57.048 27.777 1.00 14.10 ? 284 GLN A CD 1 ATOM 2176 O OE1 . GLN A 1 284 ? 18.457 56.574 28.911 1.00 17.10 ? 284 GLN A OE1 1 ATOM 2177 N NE2 . GLN A 1 284 ? 17.422 56.856 26.945 1.00 15.38 ? 284 GLN A NE2 1 ATOM 2178 N N . PHE A 1 285 ? 24.072 56.499 26.088 1.00 11.19 ? 285 PHE A N 1 ATOM 2179 C CA . PHE A 1 285 ? 25.306 55.793 26.294 1.00 10.55 ? 285 PHE A CA 1 ATOM 2180 C C . PHE A 1 285 ? 26.456 56.564 25.649 1.00 10.62 ? 285 PHE A C 1 ATOM 2181 O O . PHE A 1 285 ? 27.520 56.004 25.432 1.00 10.72 ? 285 PHE A O 1 ATOM 2182 C CB . PHE A 1 285 ? 25.179 54.340 25.836 1.00 11.51 ? 285 PHE A CB 1 ATOM 2183 C CG . PHE A 1 285 ? 24.170 53.575 26.680 1.00 11.68 ? 285 PHE A CG 1 ATOM 2184 C CD1 . PHE A 1 285 ? 24.559 52.946 27.868 1.00 11.76 ? 285 PHE A CD1 1 ATOM 2185 C CD2 . PHE A 1 285 ? 22.830 53.590 26.315 1.00 12.24 ? 285 PHE A CD2 1 ATOM 2186 C CE1 . PHE A 1 285 ? 23.557 52.342 28.690 1.00 12.62 ? 285 PHE A CE1 1 ATOM 2187 C CE2 . PHE A 1 285 ? 21.831 52.986 27.128 1.00 12.89 ? 285 PHE A CE2 1 ATOM 2188 C CZ . PHE A 1 285 ? 22.220 52.371 28.312 1.00 13.90 ? 285 PHE A CZ 1 ATOM 2189 N N . ASP A 1 286 ? 26.192 57.841 25.369 1.00 10.22 ? 286 ASP A N 1 ATOM 2190 C CA . ASP A 1 286 ? 27.297 58.758 24.938 1.00 10.22 ? 286 ASP A CA 1 ATOM 2191 C C . ASP A 1 286 ? 27.561 59.594 26.225 1.00 8.74 ? 286 ASP A C 1 ATOM 2192 O O . ASP A 1 286 ? 26.874 60.609 26.437 1.00 11.17 ? 286 ASP A O 1 ATOM 2193 C CB . ASP A 1 286 ? 26.856 59.634 23.796 1.00 10.16 ? 286 ASP A CB 1 ATOM 2194 C CG . ASP A 1 286 ? 27.999 60.508 23.277 1.00 9.16 ? 286 ASP A CG 1 ATOM 2195 O OD1 . ASP A 1 286 ? 29.042 60.572 23.986 1.00 9.56 ? 286 ASP A OD1 1 ATOM 2196 O OD2 . ASP A 1 286 ? 27.805 61.146 22.203 1.00 10.37 ? 286 ASP A OD2 1 ATOM 2197 N N . PHE A 1 287 ? 28.539 59.165 27.025 1.00 9.75 ? 287 PHE A N 1 ATOM 2198 C CA . PHE A 1 287 ? 28.714 59.815 28.323 1.00 10.72 ? 287 PHE A CA 1 ATOM 2199 C C . PHE A 1 287 ? 29.263 61.195 28.268 1.00 12.28 ? 287 PHE A C 1 ATOM 2200 O O . PHE A 1 287 ? 29.381 61.842 29.297 1.00 13.02 ? 287 PHE A O 1 ATOM 2201 C CB . PHE A 1 287 ? 29.426 58.859 29.312 1.00 11.31 ? 287 PHE A CB 1 ATOM 2202 C CG . PHE A 1 287 ? 28.622 57.575 29.544 1.00 10.56 ? 287 PHE A CG 1 ATOM 2203 C CD1 . PHE A 1 287 ? 27.623 57.543 30.530 1.00 11.95 ? 287 PHE A CD1 1 ATOM 2204 C CD2 . PHE A 1 287 ? 28.812 56.429 28.786 1.00 11.97 ? 287 PHE A CD2 1 ATOM 2205 C CE1 . PHE A 1 287 ? 26.849 56.386 30.733 1.00 12.70 ? 287 PHE A CE1 1 ATOM 2206 C CE2 . PHE A 1 287 ? 28.035 55.281 28.991 1.00 12.80 ? 287 PHE A CE2 1 ATOM 2207 C CZ . PHE A 1 287 ? 27.048 55.261 29.980 1.00 13.06 ? 287 PHE A CZ 1 ATOM 2208 N N . LYS A 1 288 ? 29.597 61.694 27.063 1.00 12.40 ? 288 LYS A N 1 ATOM 2209 C CA . LYS A 1 288 ? 29.997 63.096 26.967 1.00 11.97 ? 288 LYS A CA 1 ATOM 2210 C C . LYS A 1 288 ? 28.798 64.026 26.922 1.00 12.68 ? 288 LYS A C 1 ATOM 2211 O O . LYS A 1 288 ? 28.961 65.263 26.946 1.00 13.33 ? 288 LYS A O 1 ATOM 2212 C CB . LYS A 1 288 ? 30.845 63.312 25.672 1.00 12.34 ? 288 LYS A CB 1 ATOM 2213 C CG . LYS A 1 288 ? 31.710 64.599 25.734 1.00 10.25 ? 288 LYS A CG 1 ATOM 2214 C CD . LYS A 1 288 ? 32.447 64.799 24.384 1.00 10.41 ? 288 LYS A CD 1 ATOM 2215 C CE . LYS A 1 288 ? 33.153 66.127 24.558 1.00 11.99 ? 288 LYS A CE 1 ATOM 2216 N NZ . LYS A 1 288 ? 33.909 66.423 23.219 1.00 16.39 ? 288 LYS A NZ 1 ATOM 2217 N N . ARG A 1 289 ? 27.578 63.508 26.856 1.00 13.12 ? 289 ARG A N 1 ATOM 2218 C CA . ARG A 1 289 ? 26.394 64.347 26.751 1.00 15.11 ? 289 ARG A CA 1 ATOM 2219 C C . ARG A 1 289 ? 25.623 64.644 28.077 1.00 16.42 ? 289 ARG A C 1 ATOM 2220 O O . ARG A 1 289 ? 24.430 64.852 28.023 1.00 16.87 ? 289 ARG A O 1 ATOM 2221 C CB . ARG A 1 289 ? 25.431 63.711 25.743 1.00 13.18 ? 289 ARG A CB 1 ATOM 2222 C CG . ARG A 1 289 ? 26.075 63.564 24.352 1.00 13.14 ? 289 ARG A CG 1 ATOM 2223 C CD . ARG A 1 289 ? 25.049 63.136 23.373 1.00 12.49 ? 289 ARG A CD 1 ATOM 2224 N NE . ARG A 1 289 ? 25.590 62.827 22.037 1.00 12.43 ? 289 ARG A NE 1 ATOM 2225 C CZ . ARG A 1 289 ? 25.147 63.378 20.925 1.00 12.50 ? 289 ARG A CZ 1 ATOM 2226 N NH1 . ARG A 1 289 ? 24.169 64.287 20.902 1.00 13.97 ? 289 ARG A NH1 1 ATOM 2227 N NH2 . ARG A 1 289 ? 25.672 62.977 19.771 1.00 13.28 ? 289 ARG A NH2 1 ATOM 2228 N N . MET A 1 290 ? 26.265 64.659 29.245 1.00 19.93 ? 290 MET A N 1 ATOM 2229 C CA . MET A 1 290 ? 25.426 64.949 30.431 1.00 21.76 ? 290 MET A CA 1 ATOM 2230 C C . MET A 1 290 ? 25.335 66.469 30.846 1.00 22.69 ? 290 MET A C 1 ATOM 2231 O O . MET A 1 290 ? 24.550 66.820 31.802 1.00 24.44 ? 290 MET A O 1 ATOM 2232 C CB . MET A 1 290 ? 25.809 64.002 31.619 1.00 21.51 ? 290 MET A CB 1 ATOM 2233 C CG . MET A 1 290 ? 25.785 62.566 31.287 1.00 22.94 ? 290 MET A CG 1 ATOM 2234 S SD . MET A 1 290 ? 26.276 61.378 32.654 1.00 24.52 ? 290 MET A SD 1 ATOM 2235 C CE . MET A 1 290 ? 28.079 61.438 32.505 1.00 25.47 ? 290 MET A CE 1 ATOM 2236 N N . GLY A 1 291 ? 26.078 67.373 30.148 1.00 23.29 ? 291 GLY A N 1 ATOM 2237 C CA . GLY A 1 291 ? 26.020 68.815 30.438 1.00 21.49 ? 291 GLY A CA 1 ATOM 2238 C C . GLY A 1 291 ? 27.299 69.699 30.587 1.00 21.13 ? 291 GLY A C 1 ATOM 2239 O O . GLY A 1 291 ? 27.406 70.804 30.005 1.00 21.49 ? 291 GLY A O 1 ATOM 2240 N N . SER A 1 292 ? 28.275 69.214 31.361 1.00 19.74 ? 292 SER A N 1 ATOM 2241 C CA . SER A 1 292 ? 29.516 69.951 31.620 1.00 16.22 ? 292 SER A CA 1 ATOM 2242 C C . SER A 1 292 ? 30.380 70.143 30.349 1.00 14.39 ? 292 SER A C 1 ATOM 2243 O O . SER A 1 292 ? 31.272 71.010 30.292 1.00 13.26 ? 292 SER A O 1 ATOM 2244 C CB . SER A 1 292 ? 30.302 69.194 32.692 1.00 17.38 ? 292 SER A CB 1 ATOM 2245 O OG . SER A 1 292 ? 30.804 67.951 32.212 1.00 19.09 ? 292 SER A OG 1 ATOM 2246 N N . PHE A 1 293 ? 30.113 69.319 29.341 1.00 12.76 ? 293 PHE A N 1 ATOM 2247 C CA . PHE A 1 293 ? 30.826 69.415 28.067 1.00 11.99 ? 293 PHE A CA 1 ATOM 2248 C C . PHE A 1 293 ? 30.080 70.235 27.052 1.00 12.75 ? 293 PHE A C 1 ATOM 2249 O O . PHE A 1 293 ? 30.533 70.310 25.902 1.00 12.88 ? 293 PHE A O 1 ATOM 2250 C CB . PHE A 1 293 ? 31.097 67.996 27.434 1.00 13.10 ? 293 PHE A CB 1 ATOM 2251 C CG . PHE A 1 293 ? 32.042 67.129 28.231 1.00 12.93 ? 293 PHE A CG 1 ATOM 2252 C CD1 . PHE A 1 293 ? 33.402 67.257 28.066 1.00 13.46 ? 293 PHE A CD1 1 ATOM 2253 C CD2 . PHE A 1 293 ? 31.534 66.202 29.141 1.00 14.99 ? 293 PHE A CD2 1 ATOM 2254 C CE1 . PHE A 1 293 ? 34.292 66.432 28.818 1.00 15.41 ? 293 PHE A CE1 1 ATOM 2255 C CE2 . PHE A 1 293 ? 32.421 65.389 29.894 1.00 16.16 ? 293 PHE A CE2 1 ATOM 2256 C CZ . PHE A 1 293 ? 33.780 65.529 29.706 1.00 15.53 ? 293 PHE A CZ 1 ATOM 2257 N N . GLY A 1 294 ? 28.927 70.778 27.457 1.00 13.20 ? 294 GLY A N 1 ATOM 2258 C CA . GLY A 1 294 ? 28.178 71.602 26.527 1.00 13.98 ? 294 GLY A CA 1 ATOM 2259 C C . GLY A 1 294 ? 27.428 70.808 25.460 1.00 13.32 ? 294 GLY A C 1 ATOM 2260 O O . GLY A 1 294 ? 27.100 71.326 24.379 1.00 13.75 ? 294 GLY A O 1 ATOM 2261 N N . LEU A 1 295 ? 27.168 69.523 25.750 1.00 13.75 ? 295 LEU A N 1 ATOM 2262 C CA . LEU A 1 295 ? 26.447 68.661 24.846 1.00 13.53 ? 295 LEU A CA 1 ATOM 2263 C C . LEU A 1 295 ? 25.208 68.117 25.534 1.00 14.50 ? 295 LEU A C 1 ATOM 2264 O O . LEU A 1 295 ? 25.128 68.078 26.756 1.00 15.59 ? 295 LEU A O 1 ATOM 2265 C CB . LEU A 1 295 ? 27.345 67.499 24.393 1.00 13.75 ? 295 LEU A CB 1 ATOM 2266 C CG . LEU A 1 295 ? 28.666 67.895 23.700 1.00 14.23 ? 295 LEU A CG 1 ATOM 2267 C CD1 . LEU A 1 295 ? 29.466 66.648 23.367 1.00 16.25 ? 295 LEU A CD1 1 ATOM 2268 C CD2 . LEU A 1 295 ? 28.359 68.653 22.416 1.00 14.95 ? 295 LEU A CD2 1 ATOM 2269 N N . SER A 1 296 ? 24.244 67.719 24.719 1.00 14.88 ? 296 SER A N 1 ATOM 2270 C CA . SER A 1 296 ? 22.999 67.119 25.225 1.00 16.10 ? 296 SER A CA 1 ATOM 2271 C C . SER A 1 296 ? 22.449 66.145 24.183 1.00 16.29 ? 296 SER A C 1 ATOM 2272 O O . SER A 1 296 ? 23.002 66.018 23.084 1.00 14.45 ? 296 SER A O 1 ATOM 2273 C CB . SER A 1 296 ? 21.998 68.254 25.553 1.00 17.21 ? 296 SER A CB 1 ATOM 2274 O OG . SER A 1 296 ? 21.666 69.015 24.403 1.00 18.66 ? 296 SER A OG 1 ATOM 2275 N N . CYS A 1 297 ? 21.394 65.412 24.545 1.00 14.65 ? 297 CYS A N 1 ATOM 2276 C CA . CYS A 1 297 ? 20.723 64.448 23.664 1.00 15.35 ? 297 CYS A CA 1 ATOM 2277 C C . CYS A 1 297 ? 19.484 65.107 23.062 1.00 15.97 ? 297 CYS A C 1 ATOM 2278 O O . CYS A 1 297 ? 18.585 65.507 23.808 1.00 17.42 ? 297 CYS A O 1 ATOM 2279 C CB . CYS A 1 297 ? 20.311 63.195 24.493 1.00 15.90 ? 297 CYS A CB 1 ATOM 2280 S SG . CYS A 1 297 ? 21.740 62.082 24.739 1.00 15.42 ? 297 CYS A SG 1 ATOM 2281 N N . PRO A 1 298 ? 19.384 65.198 21.729 1.00 15.92 ? 298 PRO A N 1 ATOM 2282 C CA . PRO A 1 298 ? 18.195 65.846 21.155 1.00 16.96 ? 298 PRO A CA 1 ATOM 2283 C C . PRO A 1 298 ? 16.914 65.095 21.408 1.00 16.42 ? 298 PRO A C 1 ATOM 2284 O O . PRO A 1 298 ? 15.841 65.706 21.314 1.00 17.12 ? 298 PRO A O 1 ATOM 2285 C CB . PRO A 1 298 ? 18.508 66.022 19.663 1.00 18.80 ? 298 PRO A CB 1 ATOM 2286 C CG . PRO A 1 298 ? 19.771 65.261 19.410 1.00 17.50 ? 298 PRO A CG 1 ATOM 2287 C CD . PRO A 1 298 ? 20.471 65.010 20.725 1.00 16.57 ? 298 PRO A CD 1 ATOM 2288 N N . TRP A 1 299 ? 17.022 63.833 21.810 1.00 15.69 ? 299 TRP A N 1 ATOM 2289 C CA . TRP A 1 299 ? 15.798 63.038 22.065 1.00 16.04 ? 299 TRP A CA 1 ATOM 2290 C C . TRP A 1 299 ? 15.299 63.280 23.469 1.00 17.48 ? 299 TRP A C 1 ATOM 2291 O O . TRP A 1 299 ? 14.332 62.643 23.916 1.00 18.50 ? 299 TRP A O 1 ATOM 2292 C CB . TRP A 1 299 ? 16.070 61.541 21.810 1.00 15.44 ? 299 TRP A CB 1 ATOM 2293 C CG . TRP A 1 299 ? 16.459 61.323 20.356 1.00 15.00 ? 299 TRP A CG 1 ATOM 2294 C CD1 . TRP A 1 299 ? 15.619 61.141 19.307 1.00 14.02 ? 299 TRP A CD1 1 ATOM 2295 C CD2 . TRP A 1 299 ? 17.792 61.424 19.802 1.00 14.36 ? 299 TRP A CD2 1 ATOM 2296 N NE1 . TRP A 1 299 ? 16.327 61.121 18.128 1.00 15.33 ? 299 TRP A NE1 1 ATOM 2297 C CE2 . TRP A 1 299 ? 17.658 61.298 18.408 1.00 14.36 ? 299 TRP A CE2 1 ATOM 2298 C CE3 . TRP A 1 299 ? 19.062 61.608 20.362 1.00 13.75 ? 299 TRP A CE3 1 ATOM 2299 C CZ2 . TRP A 1 299 ? 18.762 61.361 17.543 1.00 15.15 ? 299 TRP A CZ2 1 ATOM 2300 C CZ3 . TRP A 1 299 ? 20.172 61.668 19.505 1.00 13.14 ? 299 TRP A CZ3 1 ATOM 2301 C CH2 . TRP A 1 299 ? 19.995 61.550 18.108 1.00 13.96 ? 299 TRP A CH2 1 ATOM 2302 N N . LYS A 1 300 ? 16.004 64.156 24.181 1.00 17.64 ? 300 LYS A N 1 ATOM 2303 C CA . LYS A 1 300 ? 15.587 64.622 25.517 1.00 19.07 ? 300 LYS A CA 1 ATOM 2304 C C . LYS A 1 300 ? 15.733 63.713 26.720 1.00 19.17 ? 300 LYS A C 1 ATOM 2305 O O . LYS A 1 300 ? 15.237 64.034 27.828 1.00 20.55 ? 300 LYS A O 1 ATOM 2306 C CB . LYS A 1 300 ? 14.154 65.159 25.445 1.00 20.66 ? 300 LYS A CB 1 ATOM 2307 C CG . LYS A 1 300 ? 13.986 66.341 24.558 1.00 22.93 ? 300 LYS A CG 1 ATOM 2308 C CD . LYS A 1 300 ? 12.493 66.696 24.419 1.00 25.88 ? 300 LYS A CD 1 ATOM 2309 C CE . LYS A 1 300 ? 12.254 68.009 23.653 1.00 28.12 ? 300 LYS A CE 1 ATOM 2310 N NZ . LYS A 1 300 ? 13.282 68.255 22.622 1.00 29.55 ? 300 LYS A NZ 1 ATOM 2311 N N . VAL A 1 301 ? 16.427 62.601 26.568 1.00 18.28 ? 301 VAL A N 1 ATOM 2312 C CA . VAL A 1 301 ? 16.695 61.754 27.715 1.00 17.44 ? 301 VAL A CA 1 ATOM 2313 C C . VAL A 1 301 ? 18.217 61.762 27.810 1.00 17.01 ? 301 VAL A C 1 ATOM 2314 O O . VAL A 1 301 ? 18.910 61.264 26.901 1.00 17.54 ? 301 VAL A O 1 ATOM 2315 C CB . VAL A 1 301 ? 16.179 60.298 27.553 1.00 17.57 ? 301 VAL A CB 1 ATOM 2316 C CG1 . VAL A 1 301 ? 16.496 59.520 28.821 1.00 17.99 ? 301 VAL A CG1 1 ATOM 2317 C CG2 . VAL A 1 301 ? 14.655 60.293 27.257 1.00 19.48 ? 301 VAL A CG2 1 ATOM 2318 N N . PRO A 1 302 ? 18.780 62.285 28.896 1.00 15.40 ? 302 PRO A N 1 ATOM 2319 C CA . PRO A 1 302 ? 20.223 62.347 29.018 1.00 15.65 ? 302 PRO A CA 1 ATOM 2320 C C . PRO A 1 302 ? 20.901 61.081 29.469 1.00 15.62 ? 302 PRO A C 1 ATOM 2321 O O . PRO A 1 302 ? 20.279 60.143 29.972 1.00 15.84 ? 302 PRO A O 1 ATOM 2322 C CB . PRO A 1 302 ? 20.427 63.484 30.038 1.00 16.85 ? 302 PRO A CB 1 ATOM 2323 C CG . PRO A 1 302 ? 19.208 63.291 30.963 1.00 18.15 ? 302 PRO A CG 1 ATOM 2324 C CD . PRO A 1 302 ? 18.099 62.973 30.026 1.00 16.19 ? 302 PRO A CD 1 ATOM 2325 N N . PRO A 1 303 ? 22.210 60.976 29.217 1.00 14.17 ? 303 PRO A N 1 ATOM 2326 C CA . PRO A 1 303 ? 22.908 59.785 29.698 1.00 15.30 ? 303 PRO A CA 1 ATOM 2327 C C . PRO A 1 303 ? 22.908 59.918 31.244 1.00 16.67 ? 303 PRO A C 1 ATOM 2328 O O . PRO A 1 303 ? 22.834 61.036 31.807 1.00 17.30 ? 303 PRO A O 1 ATOM 2329 C CB . PRO A 1 303 ? 24.364 59.974 29.227 1.00 14.65 ? 303 PRO A CB 1 ATOM 2330 C CG . PRO A 1 303 ? 24.302 61.132 28.242 1.00 15.23 ? 303 PRO A CG 1 ATOM 2331 C CD . PRO A 1 303 ? 23.122 61.976 28.634 1.00 14.80 ? 303 PRO A CD 1 ATOM 2332 N N . ARG A 1 304 ? 23.038 58.779 31.920 1.00 18.26 ? 304 ARG A N 1 ATOM 2333 C CA . ARG A 1 304 ? 23.169 58.798 33.367 1.00 19.46 ? 304 ARG A CA 1 ATOM 2334 C C . ARG A 1 304 ? 24.367 57.991 33.779 1.00 17.55 ? 304 ARG A C 1 ATOM 2335 O O . ARG A 1 304 ? 24.620 56.899 33.211 1.00 16.35 ? 304 ARG A O 1 ATOM 2336 C CB . ARG A 1 304 ? 21.927 58.203 34.021 1.00 23.53 ? 304 ARG A CB 1 ATOM 2337 C CG . ARG A 1 304 ? 20.810 59.232 34.179 1.00 29.53 ? 304 ARG A CG 1 ATOM 2338 C CD . ARG A 1 304 ? 19.645 58.609 34.905 1.00 34.59 ? 304 ARG A CD 1 ATOM 2339 N NE . ARG A 1 304 ? 19.237 57.381 34.215 1.00 39.24 ? 304 ARG A NE 1 ATOM 2340 C CZ . ARG A 1 304 ? 19.055 56.204 34.816 1.00 41.45 ? 304 ARG A CZ 1 ATOM 2341 N NH1 . ARG A 1 304 ? 19.233 56.066 36.138 1.00 42.71 ? 304 ARG A NH1 1 ATOM 2342 N NH2 . ARG A 1 304 ? 18.716 55.149 34.083 1.00 43.03 ? 304 ARG A NH2 1 ATOM 2343 N N . THR A 1 305 ? 25.124 58.488 34.747 1.00 16.84 ? 305 THR A N 1 ATOM 2344 C CA . THR A 1 305 ? 26.272 57.780 35.226 1.00 16.74 ? 305 THR A CA 1 ATOM 2345 C C . THR A 1 305 ? 25.893 56.373 35.684 1.00 15.74 ? 305 THR A C 1 ATOM 2346 O O . THR A 1 305 ? 24.894 56.210 36.396 1.00 16.66 ? 305 THR A O 1 ATOM 2347 C CB . THR A 1 305 ? 26.931 58.565 36.384 1.00 17.09 ? 305 THR A CB 1 ATOM 2348 O OG1 . THR A 1 305 ? 27.403 59.806 35.836 1.00 20.79 ? 305 THR A OG1 1 ATOM 2349 C CG2 . THR A 1 305 ? 28.045 57.817 37.036 1.00 18.55 ? 305 THR A CG2 1 ATOM 2350 N N . ILE A 1 306 ? 26.652 55.372 35.274 1.00 14.45 ? 306 ILE A N 1 ATOM 2351 C CA . ILE A 1 306 ? 26.343 53.990 35.643 1.00 14.23 ? 306 ILE A CA 1 ATOM 2352 C C . ILE A 1 306 ? 26.784 53.781 37.087 1.00 15.60 ? 306 ILE A C 1 ATOM 2353 O O . ILE A 1 306 ? 27.890 54.165 37.493 1.00 16.27 ? 306 ILE A O 1 ATOM 2354 C CB . ILE A 1 306 ? 27.068 52.999 34.672 1.00 13.77 ? 306 ILE A CB 1 ATOM 2355 C CG1 . ILE A 1 306 ? 26.720 53.305 33.203 1.00 12.85 ? 306 ILE A CG1 1 ATOM 2356 C CG2 . ILE A 1 306 ? 26.703 51.529 35.111 1.00 14.12 ? 306 ILE A CG2 1 ATOM 2357 C CD1 . ILE A 1 306 ? 25.282 53.222 32.832 1.00 13.72 ? 306 ILE A CD1 1 ATOM 2358 N N . SER A 1 307 ? 25.903 53.122 37.856 1.00 16.78 ? 307 SER A N 1 ATOM 2359 C CA . SER A 1 307 ? 26.131 52.851 39.291 1.00 17.48 ? 307 SER A CA 1 ATOM 2360 C C . SER A 1 307 ? 25.642 51.460 39.574 1.00 18.25 ? 307 SER A C 1 ATOM 2361 O O . SER A 1 307 ? 24.925 50.869 38.770 1.00 17.36 ? 307 SER A O 1 ATOM 2362 C CB . SER A 1 307 ? 25.262 53.784 40.146 1.00 17.80 ? 307 SER A CB 1 ATOM 2363 O OG . SER A 1 307 ? 23.871 53.515 39.993 1.00 17.51 ? 307 SER A OG 1 ATOM 2364 N N . ASP A 1 308 ? 25.954 50.977 40.766 1.00 19.80 ? 308 ASP A N 1 ATOM 2365 C CA . ASP A 1 308 ? 25.447 49.660 41.112 1.00 20.59 ? 308 ASP A CA 1 ATOM 2366 C C . ASP A 1 308 ? 23.900 49.610 41.172 1.00 20.23 ? 308 ASP A C 1 ATOM 2367 O O . ASP A 1 308 ? 23.350 48.532 40.912 1.00 19.74 ? 308 ASP A O 1 ATOM 2368 C CB . ASP A 1 308 ? 26.072 49.163 42.423 1.00 23.85 ? 308 ASP A CB 1 ATOM 2369 C CG . ASP A 1 308 ? 27.571 48.897 42.310 1.00 26.25 ? 308 ASP A CG 1 ATOM 2370 O OD1 . ASP A 1 308 ? 28.150 48.896 41.197 1.00 28.23 ? 308 ASP A OD1 1 ATOM 2371 O OD2 . ASP A 1 308 ? 28.228 48.648 43.351 1.00 29.33 ? 308 ASP A OD2 1 ATOM 2372 N N . GLN A 1 309 ? 23.196 50.720 41.460 1.00 19.24 ? 309 GLN A N 1 ATOM 2373 C CA . GLN A 1 309 ? 21.714 50.741 41.537 1.00 19.12 ? 309 GLN A CA 1 ATOM 2374 C C A GLN A 1 309 ? 20.977 50.925 40.210 0.50 18.68 ? 309 GLN A C 1 ATOM 2375 C C B GLN A 1 309 ? 21.084 50.684 40.179 0.50 20.28 ? 309 GLN A C 1 ATOM 2376 O O A GLN A 1 309 ? 19.727 50.820 40.132 0.50 17.50 ? 309 GLN A O 1 ATOM 2377 O O B GLN A 1 309 ? 19.978 50.165 40.044 0.50 20.51 ? 309 GLN A O 1 ATOM 2378 C CB A GLN A 1 309 ? 21.188 51.810 42.517 0.50 18.11 ? 309 GLN A CB 1 ATOM 2379 C CB B GLN A 1 309 ? 21.196 52.046 42.154 0.50 21.09 ? 309 GLN A CB 1 ATOM 2380 C CG A GLN A 1 309 ? 21.682 51.664 43.956 0.50 17.15 ? 309 GLN A CG 1 ATOM 2381 C CG B GLN A 1 309 ? 21.028 52.247 43.634 0.50 22.78 ? 309 GLN A CG 1 ATOM 2382 C CD A GLN A 1 309 ? 23.171 51.874 44.073 0.50 17.18 ? 309 GLN A CD 1 ATOM 2383 C CD B GLN A 1 309 ? 20.671 53.708 43.881 0.50 22.47 ? 309 GLN A CD 1 ATOM 2384 O OE1 A GLN A 1 309 ? 23.714 52.836 43.521 0.50 16.78 ? 309 GLN A OE1 1 ATOM 2385 O OE1 B GLN A 1 309 ? 19.880 54.318 43.129 0.50 22.43 ? 309 GLN A OE1 1 ATOM 2386 N NE2 A GLN A 1 309 ? 23.839 50.988 44.808 0.50 16.92 ? 309 GLN A NE2 1 ATOM 2387 N NE2 B GLN A 1 309 ? 21.270 54.291 44.900 0.50 24.57 ? 309 GLN A NE2 1 ATOM 2388 N N . ASN A 1 310 ? 21.723 51.262 39.167 1.00 18.87 ? 310 ASN A N 1 ATOM 2389 C CA . ASN A 1 310 ? 21.085 51.345 37.875 1.00 17.16 ? 310 ASN A CA 1 ATOM 2390 C C . ASN A 1 310 ? 21.758 50.466 36.825 1.00 15.55 ? 310 ASN A C 1 ATOM 2391 O O . ASN A 1 310 ? 21.183 50.380 35.768 1.00 16.03 ? 310 ASN A O 1 ATOM 2392 C CB . ASN A 1 310 ? 21.027 52.799 37.369 1.00 17.62 ? 310 ASN A CB 1 ATOM 2393 C CG . ASN A 1 310 ? 22.412 53.371 37.005 1.00 16.43 ? 310 ASN A CG 1 ATOM 2394 O OD1 . ASN A 1 310 ? 23.372 52.644 36.758 1.00 16.44 ? 310 ASN A OD1 1 ATOM 2395 N ND2 . ASN A 1 310 ? 22.489 54.697 36.984 1.00 18.84 ? 310 ASN A ND2 1 ATOM 2396 N N . VAL A 1 311 ? 22.853 49.802 37.150 1.00 14.76 ? 311 VAL A N 1 ATOM 2397 C CA . VAL A 1 311 ? 23.580 49.055 36.061 1.00 14.91 ? 311 VAL A CA 1 ATOM 2398 C C . VAL A 1 311 ? 22.721 47.937 35.471 1.00 16.35 ? 311 VAL A C 1 ATOM 2399 O O . VAL A 1 311 ? 22.742 47.699 34.255 1.00 16.43 ? 311 VAL A O 1 ATOM 2400 C CB . VAL A 1 311 ? 24.963 48.547 36.504 1.00 14.99 ? 311 VAL A CB 1 ATOM 2401 C CG1 . VAL A 1 311 ? 24.847 47.433 37.535 1.00 17.04 ? 311 VAL A CG1 1 ATOM 2402 C CG2 . VAL A 1 311 ? 25.764 48.019 35.257 1.00 15.00 ? 311 VAL A CG2 1 ATOM 2403 N N . ALA A 1 312 ? 21.915 47.255 36.272 1.00 16.18 ? 312 ALA A N 1 ATOM 2404 C CA . ALA A 1 312 ? 21.103 46.215 35.666 1.00 15.94 ? 312 ALA A CA 1 ATOM 2405 C C . ALA A 1 312 ? 20.097 46.777 34.684 1.00 16.63 ? 312 ALA A C 1 ATOM 2406 O O . ALA A 1 312 ? 19.920 46.223 33.590 1.00 17.31 ? 312 ALA A O 1 ATOM 2407 C CB . ALA A 1 312 ? 20.359 45.375 36.776 1.00 16.71 ? 312 ALA A CB 1 ATOM 2408 N N . ALA A 1 313 ? 19.400 47.859 35.016 1.00 15.90 ? 313 ALA A N 1 ATOM 2409 C CA . ALA A 1 313 ? 18.438 48.450 34.117 1.00 16.91 ? 313 ALA A CA 1 ATOM 2410 C C . ALA A 1 313 ? 19.135 49.061 32.915 1.00 17.11 ? 313 ALA A C 1 ATOM 2411 O O . ALA A 1 313 ? 18.633 48.929 31.825 1.00 16.72 ? 313 ALA A O 1 ATOM 2412 C CB . ALA A 1 313 ? 17.553 49.536 34.827 1.00 17.46 ? 313 ALA A CB 1 ATOM 2413 N N . ARG A 1 314 ? 20.263 49.714 33.141 1.00 16.64 ? 314 ARG A N 1 ATOM 2414 C CA . ARG A 1 314 ? 20.961 50.337 31.993 1.00 16.04 ? 314 ARG A CA 1 ATOM 2415 C C . ARG A 1 314 ? 21.457 49.247 31.049 1.00 15.31 ? 314 ARG A C 1 ATOM 2416 O O . ARG A 1 314 ? 21.379 49.420 29.821 1.00 15.59 ? 314 ARG A O 1 ATOM 2417 C CB . ARG A 1 314 ? 22.146 51.157 32.500 1.00 15.50 ? 314 ARG A CB 1 ATOM 2418 C CG . ARG A 1 314 ? 21.796 52.341 33.373 1.00 16.86 ? 314 ARG A CG 1 ATOM 2419 C CD . ARG A 1 314 ? 21.481 53.566 32.549 1.00 20.01 ? 314 ARG A CD 1 ATOM 2420 N NE . ARG A 1 314 ? 20.110 53.609 32.084 1.00 21.93 ? 314 ARG A NE 1 ATOM 2421 C CZ . ARG A 1 314 ? 19.624 54.477 31.197 1.00 21.76 ? 314 ARG A CZ 1 ATOM 2422 N NH1 . ARG A 1 314 ? 20.418 55.402 30.624 1.00 22.69 ? 314 ARG A NH1 1 ATOM 2423 N NH2 . ARG A 1 314 ? 18.324 54.497 30.926 1.00 22.61 ? 314 ARG A NH2 1 ATOM 2424 N N . SER A 1 315 ? 21.943 48.156 31.615 1.00 15.08 ? 315 SER A N 1 ATOM 2425 C CA . SER A 1 315 ? 22.429 47.000 30.800 1.00 16.42 ? 315 SER A CA 1 ATOM 2426 C C . SER A 1 315 ? 21.320 46.381 30.022 1.00 17.68 ? 315 SER A C 1 ATOM 2427 O O . SER A 1 315 ? 21.509 45.955 28.871 1.00 18.22 ? 315 SER A O 1 ATOM 2428 C CB . SER A 1 315 ? 23.055 45.932 31.665 1.00 15.81 ? 315 SER A CB 1 ATOM 2429 O OG . SER A 1 315 ? 24.229 46.409 32.216 1.00 16.39 ? 315 SER A OG 1 ATOM 2430 N N . ASP A 1 316 ? 20.134 46.272 30.604 1.00 17.42 ? 316 ASP A N 1 ATOM 2431 C CA . ASP A 1 316 ? 19.015 45.682 29.866 1.00 17.18 ? 316 ASP A CA 1 ATOM 2432 C C . ASP A 1 316 ? 18.577 46.541 28.658 1.00 16.91 ? 316 ASP A C 1 ATOM 2433 O O A ASP A 1 316 ? 18.107 46.040 27.623 0.50 15.22 ? 316 ASP A O 1 ATOM 2434 O O B ASP A 1 316 ? 18.667 45.894 27.618 0.50 16.45 ? 316 ASP A O 1 ATOM 2435 C CB A ASP A 1 316 ? 17.840 45.475 30.803 0.50 17.60 ? 316 ASP A CB 1 ATOM 2436 C CB B ASP A 1 316 ? 17.725 46.000 30.817 0.50 19.97 ? 316 ASP A CB 1 ATOM 2437 C CG A ASP A 1 316 ? 16.905 44.420 30.304 0.50 17.64 ? 316 ASP A CG 1 ATOM 2438 C CG B ASP A 1 316 ? 17.161 44.743 31.355 0.50 21.89 ? 316 ASP A CG 1 ATOM 2439 O OD1 A ASP A 1 316 ? 15.708 44.738 30.119 0.50 19.43 ? 316 ASP A OD1 1 ATOM 2440 O OD1 B ASP A 1 316 ? 17.882 44.095 32.118 0.50 21.24 ? 316 ASP A OD1 1 ATOM 2441 O OD2 A ASP A 1 316 ? 17.391 43.286 30.102 0.50 17.95 ? 316 ASP A OD2 1 ATOM 2442 O OD2 B ASP A 1 316 ? 16.000 44.412 31.002 0.50 23.00 ? 316 ASP A OD2 1 ATOM 2443 N N . LEU A 1 317 ? 18.681 47.851 28.791 1.00 16.60 ? 317 LEU A N 1 ATOM 2444 C CA . LEU A 1 317 ? 18.358 48.726 27.659 1.00 16.88 ? 317 LEU A CA 1 ATOM 2445 C C . LEU A 1 317 ? 19.423 48.601 26.582 1.00 14.21 ? 317 LEU A C 1 ATOM 2446 O O . LEU A 1 317 ? 19.106 48.464 25.406 1.00 14.44 ? 317 LEU A O 1 ATOM 2447 C CB . LEU A 1 317 ? 18.297 50.211 28.101 1.00 18.50 ? 317 LEU A CB 1 ATOM 2448 C CG . LEU A 1 317 ? 16.937 50.733 28.525 1.00 20.87 ? 317 LEU A CG 1 ATOM 2449 C CD1 . LEU A 1 317 ? 17.162 52.032 29.326 1.00 22.68 ? 317 LEU A CD1 1 ATOM 2450 C CD2 . LEU A 1 317 ? 16.001 50.972 27.321 1.00 22.49 ? 317 LEU A CD2 1 ATOM 2451 N N . LEU A 1 318 ? 20.664 48.608 27.029 1.00 13.33 ? 318 LEU A N 1 ATOM 2452 C CA . LEU A 1 318 ? 21.778 48.563 26.066 1.00 12.55 ? 318 LEU A CA 1 ATOM 2453 C C . LEU A 1 318 ? 21.885 47.241 25.351 1.00 12.94 ? 318 LEU A C 1 ATOM 2454 O O . LEU A 1 318 ? 22.019 47.186 24.094 1.00 12.93 ? 318 LEU A O 1 ATOM 2455 C CB . LEU A 1 318 ? 23.088 48.900 26.764 1.00 12.70 ? 318 LEU A CB 1 ATOM 2456 C CG . LEU A 1 318 ? 24.315 48.992 25.824 1.00 13.13 ? 318 LEU A CG 1 ATOM 2457 C CD1 . LEU A 1 318 ? 24.066 50.120 24.785 1.00 13.23 ? 318 LEU A CD1 1 ATOM 2458 C CD2 . LEU A 1 318 ? 25.577 49.288 26.646 1.00 13.75 ? 318 LEU A CD2 1 ATOM 2459 N N . VAL A 1 319 ? 21.796 46.152 26.090 1.00 12.94 ? 319 VAL A N 1 ATOM 2460 C CA . VAL A 1 319 ? 21.919 44.831 25.469 1.00 12.84 ? 319 VAL A CA 1 ATOM 2461 C C . VAL A 1 319 ? 20.749 44.626 24.490 1.00 12.72 ? 319 VAL A C 1 ATOM 2462 O O . VAL A 1 319 ? 20.901 43.970 23.463 1.00 12.86 ? 319 VAL A O 1 ATOM 2463 C CB . VAL A 1 319 ? 21.947 43.699 26.529 1.00 13.26 ? 319 VAL A CB 1 ATOM 2464 C CG1 . VAL A 1 319 ? 21.789 42.336 25.798 1.00 13.26 ? 319 VAL A CG1 1 ATOM 2465 C CG2 . VAL A 1 319 ? 23.248 43.696 27.282 1.00 14.38 ? 319 VAL A CG2 1 ATOM 2466 N N . ASP A 1 320 ? 19.568 45.142 24.802 1.00 12.84 ? 320 ASP A N 1 ATOM 2467 C CA . ASP A 1 320 ? 18.432 45.036 23.890 1.00 13.20 ? 320 ASP A CA 1 ATOM 2468 C C . ASP A 1 320 ? 18.743 45.782 22.557 1.00 12.63 ? 320 ASP A C 1 ATOM 2469 O O . ASP A 1 320 ? 18.392 45.288 21.478 1.00 12.01 ? 320 ASP A O 1 ATOM 2470 C CB . ASP A 1 320 ? 17.160 45.580 24.579 1.00 14.99 ? 320 ASP A CB 1 ATOM 2471 C CG . ASP A 1 320 ? 15.973 45.651 23.676 1.00 13.97 ? 320 ASP A CG 1 ATOM 2472 O OD1 . ASP A 1 320 ? 15.445 44.569 23.311 1.00 18.13 ? 320 ASP A OD1 1 ATOM 2473 O OD2 . ASP A 1 320 ? 15.486 46.732 23.303 1.00 16.32 ? 320 ASP A OD2 1 ATOM 2474 N N . GLN A 1 321 ? 19.363 46.961 22.626 1.00 11.58 ? 321 GLN A N 1 ATOM 2475 C CA . GLN A 1 321 ? 19.758 47.649 21.363 1.00 10.81 ? 321 GLN A CA 1 ATOM 2476 C C . GLN A 1 321 ? 20.779 46.796 20.613 1.00 10.02 ? 321 GLN A C 1 ATOM 2477 O O . GLN A 1 321 ? 20.675 46.669 19.384 1.00 10.90 ? 321 GLN A O 1 ATOM 2478 C CB . GLN A 1 321 ? 20.396 48.993 21.717 1.00 10.52 ? 321 GLN A CB 1 ATOM 2479 C CG . GLN A 1 321 ? 19.398 50.046 22.181 1.00 12.33 ? 321 GLN A CG 1 ATOM 2480 C CD . GLN A 1 321 ? 18.349 50.257 21.102 1.00 12.75 ? 321 GLN A CD 1 ATOM 2481 O OE1 . GLN A 1 321 ? 18.654 50.662 19.989 1.00 13.12 ? 321 GLN A OE1 1 ATOM 2482 N NE2 . GLN A 1 321 ? 17.077 49.963 21.415 1.00 13.85 ? 321 GLN A NE2 1 ATOM 2483 N N . TRP A 1 322 ? 21.764 46.246 21.313 1.00 10.33 ? 322 TRP A N 1 ATOM 2484 C CA . TRP A 1 322 ? 22.764 45.420 20.647 1.00 11.25 ? 322 TRP A CA 1 ATOM 2485 C C . TRP A 1 322 ? 22.136 44.220 19.956 1.00 12.00 ? 322 TRP A C 1 ATOM 2486 O O . TRP A 1 322 ? 22.507 43.873 18.822 1.00 11.79 ? 322 TRP A O 1 ATOM 2487 C CB . TRP A 1 322 ? 23.788 44.903 21.650 1.00 10.75 ? 322 TRP A CB 1 ATOM 2488 C CG . TRP A 1 322 ? 24.742 45.971 22.206 1.00 11.16 ? 322 TRP A CG 1 ATOM 2489 C CD1 . TRP A 1 322 ? 24.961 47.247 21.741 1.00 11.17 ? 322 TRP A CD1 1 ATOM 2490 C CD2 . TRP A 1 322 ? 25.622 45.794 23.324 1.00 11.08 ? 322 TRP A CD2 1 ATOM 2491 N NE1 . TRP A 1 322 ? 25.941 47.871 22.516 1.00 11.43 ? 322 TRP A NE1 1 ATOM 2492 C CE2 . TRP A 1 322 ? 26.354 47.003 23.487 1.00 11.50 ? 322 TRP A CE2 1 ATOM 2493 C CE3 . TRP A 1 322 ? 25.871 44.720 24.212 1.00 12.57 ? 322 TRP A CE3 1 ATOM 2494 C CZ2 . TRP A 1 322 ? 27.319 47.181 24.505 1.00 12.79 ? 322 TRP A CZ2 1 ATOM 2495 C CZ3 . TRP A 1 322 ? 26.832 44.894 25.233 1.00 12.63 ? 322 TRP A CZ3 1 ATOM 2496 C CH2 . TRP A 1 322 ? 27.539 46.103 25.372 1.00 13.53 ? 322 TRP A CH2 1 ATOM 2497 N N . LYS A 1 323 ? 21.188 43.564 20.631 1.00 11.90 ? 323 LYS A N 1 ATOM 2498 C CA . LYS A 1 323 ? 20.606 42.351 20.020 1.00 12.52 ? 323 LYS A CA 1 ATOM 2499 C C . LYS A 1 323 ? 19.752 42.700 18.839 1.00 12.42 ? 323 LYS A C 1 ATOM 2500 O O . LYS A 1 323 ? 19.648 41.926 17.896 1.00 13.05 ? 323 LYS A O 1 ATOM 2501 C CB . LYS A 1 323 ? 19.848 41.518 21.097 1.00 13.21 ? 323 LYS A CB 1 ATOM 2502 C CG . LYS A 1 323 ? 20.848 40.744 21.973 1.00 13.97 ? 323 LYS A CG 1 ATOM 2503 C CD . LYS A 1 323 ? 20.179 39.947 23.109 1.00 14.73 ? 323 LYS A CD 1 ATOM 2504 C CE . LYS A 1 323 ? 21.191 39.077 23.765 1.00 15.65 ? 323 LYS A CE 1 ATOM 2505 N NZ . LYS A 1 323 ? 20.492 38.267 24.776 1.00 19.05 ? 323 LYS A NZ 1 ATOM 2506 N N . LYS A 1 324 ? 19.123 43.858 18.851 1.00 11.22 ? 324 LYS A N 1 ATOM 2507 C CA . LYS A 1 324 ? 18.385 44.324 17.674 1.00 11.45 ? 324 LYS A CA 1 ATOM 2508 C C . LYS A 1 324 ? 19.378 44.593 16.511 1.00 11.77 ? 324 LYS A C 1 ATOM 2509 O O . LYS A 1 324 ? 19.160 44.170 15.383 1.00 11.67 ? 324 LYS A O 1 ATOM 2510 C CB . LYS A 1 324 ? 17.608 45.589 18.021 1.00 11.04 ? 324 LYS A CB 1 ATOM 2511 C CG . LYS A 1 324 ? 16.348 45.214 18.837 1.00 11.63 ? 324 LYS A CG 1 ATOM 2512 C CD . LYS A 1 324 ? 15.765 46.464 19.434 1.00 13.32 ? 324 LYS A CD 1 ATOM 2513 C CE . LYS A 1 324 ? 14.453 46.020 20.132 1.00 14.72 ? 324 LYS A CE 1 ATOM 2514 N NZ . LYS A 1 324 ? 13.899 47.095 21.007 1.00 16.67 ? 324 LYS A NZ 1 ATOM 2515 N N . LYS A 1 325 ? 20.459 45.322 16.787 1.00 10.41 ? 325 LYS A N 1 ATOM 2516 C CA . LYS A 1 325 ? 21.441 45.563 15.712 1.00 9.36 ? 325 LYS A CA 1 ATOM 2517 C C . LYS A 1 325 ? 21.980 44.239 15.184 1.00 9.58 ? 325 LYS A C 1 ATOM 2518 O O . LYS A 1 325 ? 22.179 44.071 13.970 1.00 9.57 ? 325 LYS A O 1 ATOM 2519 C CB . LYS A 1 325 ? 22.580 46.424 16.268 1.00 9.71 ? 325 LYS A CB 1 ATOM 2520 C CG . LYS A 1 325 ? 23.485 47.029 15.138 1.00 9.21 ? 325 LYS A CG 1 ATOM 2521 C CD . LYS A 1 325 ? 24.602 47.850 15.730 1.00 10.56 ? 325 LYS A CD 1 ATOM 2522 C CE . LYS A 1 325 ? 25.332 48.575 14.554 1.00 9.47 ? 325 LYS A CE 1 ATOM 2523 N NZ . LYS A 1 325 ? 26.556 49.240 15.126 1.00 11.32 ? 325 LYS A NZ 1 ATOM 2524 N N . ALA A 1 326 ? 22.229 43.268 16.066 1.00 10.68 ? 326 ALA A N 1 ATOM 2525 C CA . ALA A 1 326 ? 22.777 41.978 15.642 1.00 10.33 ? 326 ALA A CA 1 ATOM 2526 C C . ALA A 1 326 ? 21.833 41.217 14.692 1.00 11.31 ? 326 ALA A C 1 ATOM 2527 O O . ALA A 1 326 ? 22.293 40.366 13.923 1.00 11.60 ? 326 ALA A O 1 ATOM 2528 C CB . ALA A 1 326 ? 23.085 41.136 16.874 1.00 10.87 ? 326 ALA A CB 1 ATOM 2529 N N . GLU A 1 327 ? 20.534 41.506 14.762 1.00 11.66 ? 327 GLU A N 1 ATOM 2530 C CA . GLU A 1 327 ? 19.602 40.853 13.840 1.00 12.46 ? 327 GLU A CA 1 ATOM 2531 C C . GLU A 1 327 ? 19.840 41.196 12.376 1.00 12.03 ? 327 GLU A C 1 ATOM 2532 O O . GLU A 1 327 ? 19.373 40.486 11.471 1.00 13.31 ? 327 GLU A O 1 ATOM 2533 C CB . GLU A 1 327 ? 18.143 41.230 14.161 1.00 14.44 ? 327 GLU A CB 1 ATOM 2534 C CG . GLU A 1 327 ? 17.514 40.471 15.244 1.00 17.79 ? 327 GLU A CG 1 ATOM 2535 C CD . GLU A 1 327 ? 17.522 38.970 14.958 1.00 17.97 ? 327 GLU A CD 1 ATOM 2536 O OE1 . GLU A 1 327 ? 16.859 38.454 14.019 1.00 21.33 ? 327 GLU A OE1 1 ATOM 2537 O OE2 . GLU A 1 327 ? 18.237 38.288 15.684 1.00 19.20 ? 327 GLU A OE2 1 ATOM 2538 N N . LEU A 1 328 ? 20.553 42.288 12.139 1.00 10.86 ? 328 LEU A N 1 ATOM 2539 C CA . LEU A 1 328 ? 20.780 42.739 10.763 1.00 10.92 ? 328 LEU A CA 1 ATOM 2540 C C . LEU A 1 328 ? 21.990 42.091 10.124 1.00 10.89 ? 328 LEU A C 1 ATOM 2541 O O . LEU A 1 328 ? 22.233 42.332 8.958 1.00 11.76 ? 328 LEU A O 1 ATOM 2542 C CB . LEU A 1 328 ? 20.974 44.253 10.774 1.00 11.10 ? 328 LEU A CB 1 ATOM 2543 C CG . LEU A 1 328 ? 19.865 45.022 11.503 1.00 10.22 ? 328 LEU A CG 1 ATOM 2544 C CD1 . LEU A 1 328 ? 20.104 46.536 11.286 1.00 11.22 ? 328 LEU A CD1 1 ATOM 2545 C CD2 . LEU A 1 328 ? 18.465 44.646 10.971 1.00 12.72 ? 328 LEU A CD2 1 ATOM 2546 N N . TYR A 1 329 ? 22.714 41.273 10.870 1.00 10.13 ? 329 TYR A N 1 ATOM 2547 C CA . TYR A 1 329 ? 23.947 40.653 10.411 1.00 10.11 ? 329 TYR A CA 1 ATOM 2548 C C . TYR A 1 329 ? 23.947 39.149 10.590 1.00 11.45 ? 329 TYR A C 1 ATOM 2549 O O . TYR A 1 329 ? 23.114 38.637 11.361 1.00 12.83 ? 329 TYR A O 1 ATOM 2550 C CB . TYR A 1 329 ? 25.176 41.292 11.111 1.00 11.05 ? 329 TYR A CB 1 ATOM 2551 C CG . TYR A 1 329 ? 25.390 42.748 10.761 1.00 9.33 ? 329 TYR A CG 1 ATOM 2552 C CD1 . TYR A 1 329 ? 26.118 43.103 9.641 1.00 10.12 ? 329 TYR A CD1 1 ATOM 2553 C CD2 . TYR A 1 329 ? 24.789 43.762 11.544 1.00 10.82 ? 329 TYR A CD2 1 ATOM 2554 C CE1 . TYR A 1 329 ? 26.240 44.460 9.272 1.00 9.85 ? 329 TYR A CE1 1 ATOM 2555 C CE2 . TYR A 1 329 ? 24.911 45.099 11.208 1.00 10.99 ? 329 TYR A CE2 1 ATOM 2556 C CZ . TYR A 1 329 ? 25.637 45.429 10.056 1.00 9.14 ? 329 TYR A CZ 1 ATOM 2557 O OH . TYR A 1 329 ? 25.729 46.769 9.709 1.00 10.64 ? 329 TYR A OH 1 ATOM 2558 N N . ARG A 1 330 ? 24.876 38.452 9.942 1.00 11.22 ? 330 ARG A N 1 ATOM 2559 C CA . ARG A 1 330 ? 24.825 36.993 9.919 1.00 11.69 ? 330 ARG A CA 1 ATOM 2560 C C . ARG A 1 330 ? 25.618 36.265 10.959 1.00 12.39 ? 330 ARG A C 1 ATOM 2561 O O . ARG A 1 330 ? 25.407 35.050 11.089 1.00 15.06 ? 330 ARG A O 1 ATOM 2562 C CB . ARG A 1 330 ? 25.233 36.489 8.522 1.00 11.24 ? 330 ARG A CB 1 ATOM 2563 C CG . ARG A 1 330 ? 24.269 36.957 7.437 1.00 12.49 ? 330 ARG A CG 1 ATOM 2564 C CD . ARG A 1 330 ? 24.632 36.360 6.060 1.00 13.56 ? 330 ARG A CD 1 ATOM 2565 N NE . ARG A 1 330 ? 23.679 36.924 5.130 1.00 14.56 ? 330 ARG A NE 1 ATOM 2566 C CZ . ARG A 1 330 ? 23.333 36.420 3.952 1.00 16.93 ? 330 ARG A CZ 1 ATOM 2567 N NH1 . ARG A 1 330 ? 23.880 35.304 3.484 1.00 18.53 ? 330 ARG A NH1 1 ATOM 2568 N NH2 . ARG A 1 330 ? 22.392 37.036 3.254 1.00 18.01 ? 330 ARG A NH2 1 ATOM 2569 N N . THR A 1 331 ? 26.533 36.912 11.667 1.00 11.86 ? 331 THR A N 1 ATOM 2570 C CA . THR A 1 331 ? 27.304 36.172 12.661 1.00 11.55 ? 331 THR A CA 1 ATOM 2571 C C . THR A 1 331 ? 26.902 36.584 14.073 1.00 12.01 ? 331 THR A C 1 ATOM 2572 O O . THR A 1 331 ? 26.066 37.473 14.242 1.00 13.42 ? 331 THR A O 1 ATOM 2573 C CB . THR A 1 331 ? 28.843 36.400 12.519 1.00 12.29 ? 331 THR A CB 1 ATOM 2574 O OG1 . THR A 1 331 ? 29.207 37.714 13.001 1.00 11.76 ? 331 THR A OG1 1 ATOM 2575 C CG2 . THR A 1 331 ? 29.278 36.160 11.025 1.00 12.55 ? 331 THR A CG2 1 ATOM 2576 N N . ASN A 1 332 ? 27.548 35.940 15.061 1.00 12.67 ? 332 ASN A N 1 ATOM 2577 C CA . ASN A 1 332 ? 27.319 36.323 16.465 1.00 12.69 ? 332 ASN A CA 1 ATOM 2578 C C . ASN A 1 332 ? 28.395 37.263 16.974 1.00 11.33 ? 332 ASN A C 1 ATOM 2579 O O . ASN A 1 332 ? 28.664 37.351 18.178 1.00 13.03 ? 332 ASN A O 1 ATOM 2580 C CB . ASN A 1 332 ? 27.250 35.056 17.359 1.00 14.17 ? 332 ASN A CB 1 ATOM 2581 C CG . ASN A 1 332 ? 28.606 34.355 17.504 1.00 18.17 ? 332 ASN A CG 1 ATOM 2582 O OD1 . ASN A 1 332 ? 29.419 34.371 16.593 1.00 19.01 ? 332 ASN A OD1 1 ATOM 2583 N ND2 . ASN A 1 332 ? 28.840 33.693 18.665 1.00 19.61 ? 332 ASN A ND2 1 ATOM 2584 N N . VAL A 1 333 ? 29.004 38.005 16.048 1.00 11.06 ? 333 VAL A N 1 ATOM 2585 C CA . VAL A 1 333 ? 30.052 38.967 16.390 1.00 10.87 ? 333 VAL A CA 1 ATOM 2586 C C . VAL A 1 333 ? 29.499 40.327 15.955 1.00 9.61 ? 333 VAL A C 1 ATOM 2587 O O . VAL A 1 333 ? 29.204 40.531 14.771 1.00 10.35 ? 333 VAL A O 1 ATOM 2588 C CB . VAL A 1 333 ? 31.362 38.656 15.614 1.00 11.94 ? 333 VAL A CB 1 ATOM 2589 C CG1 . VAL A 1 333 ? 32.440 39.667 16.024 1.00 12.02 ? 333 VAL A CG1 1 ATOM 2590 C CG2 . VAL A 1 333 ? 31.791 37.204 15.863 1.00 14.18 ? 333 VAL A CG2 1 ATOM 2591 N N . LEU A 1 334 ? 29.395 41.273 16.891 1.00 9.68 ? 334 LEU A N 1 ATOM 2592 C CA . LEU A 1 334 ? 28.755 42.577 16.630 1.00 9.63 ? 334 LEU A CA 1 ATOM 2593 C C . LEU A 1 334 ? 29.724 43.739 16.790 1.00 8.97 ? 334 LEU A C 1 ATOM 2594 O O . LEU A 1 334 ? 30.465 43.846 17.778 1.00 9.90 ? 334 LEU A O 1 ATOM 2595 C CB . LEU A 1 334 ? 27.590 42.769 17.611 1.00 9.05 ? 334 LEU A CB 1 ATOM 2596 C CG . LEU A 1 334 ? 26.779 44.047 17.436 1.00 9.62 ? 334 LEU A CG 1 ATOM 2597 C CD1 . LEU A 1 334 ? 25.997 43.972 16.121 1.00 11.38 ? 334 LEU A CD1 1 ATOM 2598 C CD2 . LEU A 1 334 ? 25.807 44.190 18.629 1.00 11.05 ? 334 LEU A CD2 1 ATOM 2599 N N . LEU A 1 335 ? 29.710 44.635 15.799 1.00 8.33 ? 335 LEU A N 1 ATOM 2600 C CA . LEU A 1 335 ? 30.582 45.829 15.814 1.00 8.32 ? 335 LEU A CA 1 ATOM 2601 C C . LEU A 1 335 ? 29.779 47.015 16.347 1.00 7.43 ? 335 LEU A C 1 ATOM 2602 O O . LEU A 1 335 ? 28.732 47.363 15.797 1.00 9.56 ? 335 LEU A O 1 ATOM 2603 C CB . LEU A 1 335 ? 31.038 46.130 14.364 1.00 8.81 ? 335 LEU A CB 1 ATOM 2604 C CG . LEU A 1 335 ? 31.874 47.423 14.267 1.00 7.88 ? 335 LEU A CG 1 ATOM 2605 C CD1 . LEU A 1 335 ? 33.214 47.256 15.001 1.00 11.07 ? 335 LEU A CD1 1 ATOM 2606 C CD2 . LEU A 1 335 ? 32.126 47.712 12.762 1.00 10.90 ? 335 LEU A CD2 1 ATOM 2607 N N . ILE A 1 336 ? 30.289 47.653 17.405 1.00 8.29 ? 336 ILE A N 1 ATOM 2608 C CA . ILE A 1 336 ? 29.678 48.842 17.988 1.00 8.56 ? 336 ILE A CA 1 ATOM 2609 C C . ILE A 1 336 ? 30.702 49.997 18.013 1.00 7.61 ? 336 ILE A C 1 ATOM 2610 O O . ILE A 1 336 ? 31.507 50.114 18.924 1.00 8.86 ? 336 ILE A O 1 ATOM 2611 C CB . ILE A 1 336 ? 29.158 48.598 19.422 1.00 9.14 ? 336 ILE A CB 1 ATOM 2612 C CG1 . ILE A 1 336 ? 28.123 47.469 19.431 1.00 9.01 ? 336 ILE A CG1 1 ATOM 2613 C CG2 . ILE A 1 336 ? 28.579 49.882 19.940 1.00 9.67 ? 336 ILE A CG2 1 ATOM 2614 C CD1 . ILE A 1 336 ? 26.825 47.771 18.695 1.00 10.06 ? 336 ILE A CD1 1 ATOM 2615 N N . PRO A 1 337 ? 30.749 50.814 16.961 1.00 8.01 ? 337 PRO A N 1 ATOM 2616 C CA . PRO A 1 337 ? 31.685 51.957 17.020 1.00 8.34 ? 337 PRO A CA 1 ATOM 2617 C C . PRO A 1 337 ? 31.261 52.894 18.188 1.00 8.56 ? 337 PRO A C 1 ATOM 2618 O O . PRO A 1 337 ? 30.068 53.017 18.494 1.00 9.42 ? 337 PRO A O 1 ATOM 2619 C CB . PRO A 1 337 ? 31.426 52.691 15.689 1.00 8.83 ? 337 PRO A CB 1 ATOM 2620 C CG . PRO A 1 337 ? 30.976 51.549 14.781 1.00 8.52 ? 337 PRO A CG 1 ATOM 2621 C CD . PRO A 1 337 ? 30.058 50.722 15.654 1.00 8.81 ? 337 PRO A CD 1 ATOM 2622 N N . LEU A 1 338 ? 32.245 53.520 18.837 1.00 9.22 ? 338 LEU A N 1 ATOM 2623 C CA . LEU A 1 338 ? 31.986 54.449 19.934 1.00 8.63 ? 338 LEU A CA 1 ATOM 2624 C C . LEU A 1 338 ? 32.824 55.735 19.692 1.00 8.47 ? 338 LEU A C 1 ATOM 2625 O O . LEU A 1 338 ? 34.000 55.818 20.103 1.00 8.33 ? 338 LEU A O 1 ATOM 2626 C CB . LEU A 1 338 ? 32.352 53.792 21.261 1.00 9.44 ? 338 LEU A CB 1 ATOM 2627 C CG . LEU A 1 338 ? 32.009 54.708 22.437 1.00 10.17 ? 338 LEU A CG 1 ATOM 2628 C CD1 . LEU A 1 338 ? 30.495 54.617 22.727 1.00 12.18 ? 338 LEU A CD1 1 ATOM 2629 C CD2 . LEU A 1 338 ? 32.767 54.192 23.677 1.00 12.05 ? 338 LEU A CD2 1 ATOM 2630 N N . GLY A 1 339 ? 32.208 56.707 18.992 1.00 8.05 ? 339 GLY A N 1 ATOM 2631 C CA . GLY A 1 339 ? 32.956 57.941 18.705 1.00 8.55 ? 339 GLY A CA 1 ATOM 2632 C C . GLY A 1 339 ? 32.165 58.920 17.888 1.00 8.47 ? 339 GLY A C 1 ATOM 2633 O O . GLY A 1 339 ? 30.986 58.658 17.538 1.00 9.65 ? 339 GLY A O 1 ATOM 2634 N N . ASP A 1 340 ? 32.817 60.050 17.527 1.00 8.74 ? 340 ASP A N 1 ATOM 2635 C CA . ASP A 1 340 ? 32.186 61.108 16.781 1.00 7.99 ? 340 ASP A CA 1 ATOM 2636 C C . ASP A 1 340 ? 33.333 62.059 16.411 1.00 7.99 ? 340 ASP A C 1 ATOM 2637 O O . ASP A 1 340 ? 34.507 61.765 16.654 1.00 8.28 ? 340 ASP A O 1 ATOM 2638 C CB . ASP A 1 340 ? 31.126 61.800 17.667 1.00 9.22 ? 340 ASP A CB 1 ATOM 2639 C CG . ASP A 1 340 ? 30.029 62.481 16.875 1.00 10.93 ? 340 ASP A CG 1 ATOM 2640 O OD1 . ASP A 1 340 ? 30.222 62.787 15.660 1.00 10.91 ? 340 ASP A OD1 1 ATOM 2641 O OD2 . ASP A 1 340 ? 28.957 62.774 17.469 1.00 11.21 ? 340 ASP A OD2 1 ATOM 2642 N N . ASP A 1 341 ? 32.955 63.202 15.854 1.00 8.37 ? 341 ASP A N 1 ATOM 2643 C CA . ASP A 1 341 ? 33.964 64.175 15.344 1.00 8.31 ? 341 ASP A CA 1 ATOM 2644 C C . ASP A 1 341 ? 34.843 64.693 16.484 1.00 8.00 ? 341 ASP A C 1 ATOM 2645 O O . ASP A 1 341 ? 34.330 65.195 17.499 1.00 8.97 ? 341 ASP A O 1 ATOM 2646 C CB . ASP A 1 341 ? 33.270 65.348 14.657 1.00 8.61 ? 341 ASP A CB 1 ATOM 2647 C CG . ASP A 1 341 ? 32.599 64.965 13.358 1.00 8.64 ? 341 ASP A CG 1 ATOM 2648 O OD1 . ASP A 1 341 ? 32.493 63.756 13.068 1.00 9.17 ? 341 ASP A OD1 1 ATOM 2649 O OD2 . ASP A 1 341 ? 32.183 65.898 12.642 1.00 9.10 ? 341 ASP A OD2 1 ATOM 2650 N N . PHE A 1 342 ? 36.166 64.603 16.315 1.00 7.58 ? 342 PHE A N 1 ATOM 2651 C CA . PHE A 1 342 ? 37.105 65.136 17.297 1.00 8.51 ? 342 PHE A CA 1 ATOM 2652 C C . PHE A 1 342 ? 36.792 64.757 18.747 1.00 8.64 ? 342 PHE A C 1 ATOM 2653 O O . PHE A 1 342 ? 37.024 65.539 19.677 1.00 10.33 ? 342 PHE A O 1 ATOM 2654 C CB . PHE A 1 342 ? 37.264 66.680 17.076 1.00 7.99 ? 342 PHE A CB 1 ATOM 2655 C CG . PHE A 1 342 ? 37.821 67.035 15.723 1.00 7.67 ? 342 PHE A CG 1 ATOM 2656 C CD1 . PHE A 1 342 ? 39.209 67.029 15.496 1.00 7.79 ? 342 PHE A CD1 1 ATOM 2657 C CD2 . PHE A 1 342 ? 36.981 67.427 14.663 1.00 8.66 ? 342 PHE A CD2 1 ATOM 2658 C CE1 . PHE A 1 342 ? 39.753 67.417 14.263 1.00 7.87 ? 342 PHE A CE1 1 ATOM 2659 C CE2 . PHE A 1 342 ? 37.550 67.813 13.418 1.00 8.54 ? 342 PHE A CE2 1 ATOM 2660 C CZ . PHE A 1 342 ? 38.922 67.807 13.239 1.00 8.32 ? 342 PHE A CZ 1 ATOM 2661 N N . ARG A 1 343 ? 36.341 63.511 18.901 1.00 8.70 ? 343 ARG A N 1 ATOM 2662 C CA . ARG A 1 343 ? 36.120 62.984 20.244 1.00 7.72 ? 343 ARG A CA 1 ATOM 2663 C C . ARG A 1 343 ? 37.433 62.515 20.891 1.00 9.48 ? 343 ARG A C 1 ATOM 2664 O O . ARG A 1 343 ? 38.524 62.426 20.287 1.00 8.96 ? 343 ARG A O 1 ATOM 2665 C CB . ARG A 1 343 ? 35.101 61.821 20.200 1.00 8.56 ? 343 ARG A CB 1 ATOM 2666 C CG . ARG A 1 343 ? 33.686 62.285 19.925 1.00 9.79 ? 343 ARG A CG 1 ATOM 2667 C CD . ARG A 1 343 ? 33.214 63.311 21.023 1.00 9.83 ? 343 ARG A CD 1 ATOM 2668 N NE . ARG A 1 343 ? 31.773 63.552 20.899 1.00 10.18 ? 343 ARG A NE 1 ATOM 2669 C CZ . ARG A 1 343 ? 30.837 62.827 21.553 1.00 9.50 ? 343 ARG A CZ 1 ATOM 2670 N NH1 . ARG A 1 343 ? 31.202 61.801 22.337 1.00 9.77 ? 343 ARG A NH1 1 ATOM 2671 N NH2 . ARG A 1 343 ? 29.566 63.235 21.467 1.00 10.66 ? 343 ARG A NH2 1 ATOM 2672 N N . PHE A 1 344 ? 37.298 62.206 22.190 1.00 8.92 ? 344 PHE A N 1 ATOM 2673 C CA . PHE A 1 344 ? 38.384 61.744 23.041 1.00 9.21 ? 344 PHE A CA 1 ATOM 2674 C C . PHE A 1 344 ? 39.490 62.767 23.158 1.00 10.63 ? 344 PHE A C 1 ATOM 2675 O O . PHE A 1 344 ? 40.666 62.452 23.010 1.00 11.59 ? 344 PHE A O 1 ATOM 2676 C CB . PHE A 1 344 ? 38.849 60.340 22.573 1.00 10.00 ? 344 PHE A CB 1 ATOM 2677 C CG . PHE A 1 344 ? 37.789 59.297 22.728 1.00 10.06 ? 344 PHE A CG 1 ATOM 2678 C CD1 . PHE A 1 344 ? 37.560 58.718 23.994 1.00 11.87 ? 344 PHE A CD1 1 ATOM 2679 C CD2 . PHE A 1 344 ? 36.970 58.922 21.675 1.00 9.98 ? 344 PHE A CD2 1 ATOM 2680 C CE1 . PHE A 1 344 ? 36.518 57.788 24.164 1.00 10.86 ? 344 PHE A CE1 1 ATOM 2681 C CE2 . PHE A 1 344 ? 35.940 58.001 21.860 1.00 10.85 ? 344 PHE A CE2 1 ATOM 2682 C CZ . PHE A 1 344 ? 35.731 57.443 23.126 1.00 11.32 ? 344 PHE A CZ 1 ATOM 2683 N N . LYS A 1 345 ? 39.077 64.005 23.442 1.00 11.58 ? 345 LYS A N 1 ATOM 2684 C CA . LYS A 1 345 ? 40.058 65.095 23.605 1.00 13.38 ? 345 LYS A CA 1 ATOM 2685 C C . LYS A 1 345 ? 40.442 65.200 25.114 1.00 14.32 ? 345 LYS A C 1 ATOM 2686 O O . LYS A 1 345 ? 41.498 64.697 25.540 1.00 15.92 ? 345 LYS A O 1 ATOM 2687 C CB . LYS A 1 345 ? 39.412 66.389 23.094 1.00 14.44 ? 345 LYS A CB 1 ATOM 2688 C CG . LYS A 1 345 ? 40.289 67.619 23.164 1.00 16.56 ? 345 LYS A CG 1 ATOM 2689 C CD . LYS A 1 345 ? 39.491 68.833 22.708 1.00 19.46 ? 345 LYS A CD 1 ATOM 2690 C CE . LYS A 1 345 ? 40.265 70.109 22.881 1.00 20.81 ? 345 LYS A CE 1 ATOM 2691 N NZ . LYS A 1 345 ? 39.440 71.188 22.254 1.00 22.44 ? 345 LYS A NZ 1 ATOM 2692 N N . GLN A 1 346 ? 39.513 65.688 25.902 1.00 14.60 ? 346 GLN A N 1 ATOM 2693 C CA . GLN A 1 346 ? 39.860 65.881 27.292 1.00 16.18 ? 346 GLN A CA 1 ATOM 2694 C C . GLN A 1 346 ? 40.016 64.644 28.138 1.00 15.55 ? 346 GLN A C 1 ATOM 2695 O O . GLN A 1 346 ? 39.342 63.629 27.911 1.00 13.31 ? 346 GLN A O 1 ATOM 2696 C CB . GLN A 1 346 ? 38.834 66.790 27.912 1.00 18.98 ? 346 GLN A CB 1 ATOM 2697 C CG . GLN A 1 346 ? 38.858 68.173 27.275 1.00 22.75 ? 346 GLN A CG 1 ATOM 2698 C CD . GLN A 1 346 ? 37.681 68.995 27.737 1.00 26.04 ? 346 GLN A CD 1 ATOM 2699 O OE1 . GLN A 1 346 ? 37.813 69.843 28.641 1.00 29.80 ? 346 GLN A OE1 1 ATOM 2700 N NE2 . GLN A 1 346 ? 36.518 68.752 27.136 1.00 29.09 ? 346 GLN A NE2 1 ATOM 2701 N N . ASN A 1 347 ? 40.851 64.728 29.164 1.00 15.85 ? 347 ASN A N 1 ATOM 2702 C CA . ASN A 1 347 ? 41.050 63.596 30.059 1.00 15.42 ? 347 ASN A CA 1 ATOM 2703 C C . ASN A 1 347 ? 39.729 63.207 30.720 1.00 14.26 ? 347 ASN A C 1 ATOM 2704 O O . ASN A 1 347 ? 39.430 62.014 30.841 1.00 14.03 ? 347 ASN A O 1 ATOM 2705 C CB . ASN A 1 347 ? 42.051 63.975 31.153 1.00 17.70 ? 347 ASN A CB 1 ATOM 2706 C CG . ASN A 1 347 ? 43.386 64.183 30.609 1.00 20.20 ? 347 ASN A CG 1 ATOM 2707 O OD1 . ASN A 1 347 ? 43.912 63.299 29.943 1.00 22.48 ? 347 ASN A OD1 1 ATOM 2708 N ND2 . ASN A 1 347 ? 43.982 65.363 30.868 1.00 23.25 ? 347 ASN A ND2 1 ATOM 2709 N N . THR A 1 348 ? 38.904 64.194 31.100 1.00 13.46 ? 348 THR A N 1 ATOM 2710 C CA . THR A 1 348 ? 37.621 63.896 31.721 1.00 14.58 ? 348 THR A CA 1 ATOM 2711 C C . THR A 1 348 ? 36.701 63.130 30.776 1.00 13.90 ? 348 THR A C 1 ATOM 2712 O O . THR A 1 348 ? 35.860 62.335 31.206 1.00 14.30 ? 348 THR A O 1 ATOM 2713 C CB . THR A 1 348 ? 36.899 65.202 32.201 1.00 14.53 ? 348 THR A CB 1 ATOM 2714 O OG1 . THR A 1 348 ? 36.787 66.149 31.107 1.00 18.38 ? 348 THR A OG1 1 ATOM 2715 C CG2 . THR A 1 348 ? 37.725 65.871 33.338 1.00 16.61 ? 348 THR A CG2 1 ATOM 2716 N N . GLU A 1 349 ? 36.852 63.359 29.461 1.00 11.14 ? 349 GLU A N 1 ATOM 2717 C CA . GLU A 1 349 ? 36.028 62.642 28.483 1.00 10.87 ? 349 GLU A CA 1 ATOM 2718 C C . GLU A 1 349 ? 36.511 61.206 28.350 1.00 9.95 ? 349 GLU A C 1 ATOM 2719 O O . GLU A 1 349 ? 35.678 60.284 28.308 1.00 10.74 ? 349 GLU A O 1 ATOM 2720 C CB . GLU A 1 349 ? 36.133 63.333 27.114 1.00 10.96 ? 349 GLU A CB 1 ATOM 2721 C CG . GLU A 1 349 ? 35.312 62.633 26.039 1.00 10.28 ? 349 GLU A CG 1 ATOM 2722 C CD . GLU A 1 349 ? 35.574 63.191 24.631 1.00 10.30 ? 349 GLU A CD 1 ATOM 2723 O OE1 . GLU A 1 349 ? 36.267 64.224 24.478 1.00 12.52 ? 349 GLU A OE1 1 ATOM 2724 O OE2 . GLU A 1 349 ? 35.061 62.532 23.725 1.00 11.44 ? 349 GLU A OE2 1 ATOM 2725 N N . TRP A 1 350 ? 37.818 60.988 28.306 1.00 9.94 ? 350 TRP A N 1 ATOM 2726 C CA . TRP A 1 350 ? 38.342 59.604 28.286 1.00 10.15 ? 350 TRP A CA 1 ATOM 2727 C C . TRP A 1 350 ? 37.803 58.838 29.494 1.00 10.73 ? 350 TRP A C 1 ATOM 2728 O O . TRP A 1 350 ? 37.297 57.710 29.366 1.00 12.16 ? 350 TRP A O 1 ATOM 2729 C CB . TRP A 1 350 ? 39.858 59.561 28.352 1.00 10.65 ? 350 TRP A CB 1 ATOM 2730 C CG . TRP A 1 350 ? 40.526 59.776 27.013 1.00 10.86 ? 350 TRP A CG 1 ATOM 2731 C CD1 . TRP A 1 350 ? 40.865 60.972 26.471 1.00 11.25 ? 350 TRP A CD1 1 ATOM 2732 C CD2 . TRP A 1 350 ? 40.827 58.775 26.043 1.00 10.94 ? 350 TRP A CD2 1 ATOM 2733 N NE1 . TRP A 1 350 ? 41.374 60.791 25.215 1.00 10.78 ? 350 TRP A NE1 1 ATOM 2734 C CE2 . TRP A 1 350 ? 41.359 59.458 24.913 1.00 11.21 ? 350 TRP A CE2 1 ATOM 2735 C CE3 . TRP A 1 350 ? 40.698 57.384 25.999 1.00 12.93 ? 350 TRP A CE3 1 ATOM 2736 C CZ2 . TRP A 1 350 ? 41.757 58.785 23.758 1.00 12.89 ? 350 TRP A CZ2 1 ATOM 2737 C CZ3 . TRP A 1 350 ? 41.110 56.705 24.829 1.00 13.51 ? 350 TRP A CZ3 1 ATOM 2738 C CH2 . TRP A 1 350 ? 41.628 57.416 23.734 1.00 13.78 ? 350 TRP A CH2 1 ATOM 2739 N N . ASP A 1 351 ? 37.870 59.474 30.665 1.00 12.34 ? 351 ASP A N 1 ATOM 2740 C CA . ASP A 1 351 ? 37.372 58.820 31.867 1.00 13.51 ? 351 ASP A CA 1 ATOM 2741 C C . ASP A 1 351 ? 35.870 58.569 31.865 1.00 12.58 ? 351 ASP A C 1 ATOM 2742 O O . ASP A 1 351 ? 35.422 57.455 32.241 1.00 13.47 ? 351 ASP A O 1 ATOM 2743 C CB . ASP A 1 351 ? 37.653 59.694 33.096 1.00 16.32 ? 351 ASP A CB 1 ATOM 2744 C CG . ASP A 1 351 ? 39.091 59.748 33.474 1.00 18.72 ? 351 ASP A CG 1 ATOM 2745 O OD1 . ASP A 1 351 ? 39.876 58.820 33.142 1.00 20.63 ? 351 ASP A OD1 1 ATOM 2746 O OD2 . ASP A 1 351 ? 39.439 60.737 34.178 1.00 21.85 ? 351 ASP A OD2 1 ATOM 2747 N N . VAL A 1 352 ? 35.073 59.548 31.463 1.00 12.78 ? 352 VAL A N 1 ATOM 2748 C CA . VAL A 1 352 ? 33.646 59.357 31.528 1.00 13.76 ? 352 VAL A CA 1 ATOM 2749 C C . VAL A 1 352 ? 33.196 58.238 30.582 1.00 13.00 ? 352 VAL A C 1 ATOM 2750 O O . VAL A 1 352 ? 32.339 57.433 30.909 1.00 14.95 ? 352 VAL A O 1 ATOM 2751 C CB . VAL A 1 352 ? 32.892 60.704 31.326 1.00 15.03 ? 352 VAL A CB 1 ATOM 2752 C CG1 . VAL A 1 352 ? 32.698 61.040 29.907 1.00 14.77 ? 352 VAL A CG1 1 ATOM 2753 C CG2 . VAL A 1 352 ? 31.593 60.711 32.096 1.00 17.17 ? 352 VAL A CG2 1 ATOM 2754 N N . GLN A 1 353 ? 33.784 58.122 29.405 1.00 12.13 ? 353 GLN A N 1 ATOM 2755 C CA . GLN A 1 353 ? 33.360 57.034 28.544 1.00 11.15 ? 353 GLN A CA 1 ATOM 2756 C C . GLN A 1 353 ? 33.925 55.697 29.041 1.00 11.11 ? 353 GLN A C 1 ATOM 2757 O O . GLN A 1 353 ? 33.169 54.704 29.158 1.00 12.10 ? 353 GLN A O 1 ATOM 2758 C CB . GLN A 1 353 ? 33.878 57.288 27.104 1.00 10.32 ? 353 GLN A CB 1 ATOM 2759 C CG . GLN A 1 353 ? 33.343 58.582 26.399 1.00 10.60 ? 353 GLN A CG 1 ATOM 2760 C CD . GLN A 1 353 ? 31.900 58.499 25.953 1.00 10.28 ? 353 GLN A CD 1 ATOM 2761 O OE1 . GLN A 1 353 ? 31.077 57.761 26.549 1.00 12.07 ? 353 GLN A OE1 1 ATOM 2762 N NE2 . GLN A 1 353 ? 31.544 59.242 24.922 1.00 10.56 ? 353 GLN A NE2 1 ATOM 2763 N N . ARG A 1 354 ? 35.219 55.636 29.356 1.00 10.72 ? 354 ARG A N 1 ATOM 2764 C CA . ARG A 1 354 ? 35.826 54.389 29.790 1.00 11.74 ? 354 ARG A CA 1 ATOM 2765 C C . ARG A 1 354 ? 35.222 53.804 31.077 1.00 12.84 ? 354 ARG A C 1 ATOM 2766 O O . ARG A 1 354 ? 34.865 52.630 31.107 1.00 12.37 ? 354 ARG A O 1 ATOM 2767 C CB . ARG A 1 354 ? 37.334 54.537 30.015 1.00 11.44 ? 354 ARG A CB 1 ATOM 2768 C CG . ARG A 1 354 ? 37.963 53.216 30.439 1.00 11.55 ? 354 ARG A CG 1 ATOM 2769 C CD . ARG A 1 354 ? 39.480 53.390 30.723 1.00 12.92 ? 354 ARG A CD 1 ATOM 2770 N NE . ARG A 1 354 ? 39.724 54.461 31.697 1.00 15.18 ? 354 ARG A NE 1 ATOM 2771 C CZ . ARG A 1 354 ? 39.573 54.355 33.012 1.00 15.43 ? 354 ARG A CZ 1 ATOM 2772 N NH1 . ARG A 1 354 ? 39.144 53.227 33.565 1.00 15.80 ? 354 ARG A NH1 1 ATOM 2773 N NH2 . ARG A 1 354 ? 39.927 55.372 33.790 1.00 18.77 ? 354 ARG A NH2 1 ATOM 2774 N N . VAL A 1 355 ? 35.099 54.613 32.114 1.00 13.23 ? 355 VAL A N 1 ATOM 2775 C CA . VAL A 1 355 ? 34.600 54.049 33.374 1.00 13.57 ? 355 VAL A CA 1 ATOM 2776 C C . VAL A 1 355 ? 33.181 53.582 33.270 1.00 12.64 ? 355 VAL A C 1 ATOM 2777 O O . VAL A 1 355 ? 32.838 52.489 33.836 1.00 14.78 ? 355 VAL A O 1 ATOM 2778 C CB . VAL A 1 355 ? 34.770 55.099 34.518 1.00 15.32 ? 355 VAL A CB 1 ATOM 2779 C CG1 . VAL A 1 355 ? 34.240 54.550 35.854 1.00 19.58 ? 355 VAL A CG1 1 ATOM 2780 C CG2 . VAL A 1 355 ? 36.257 55.432 34.716 1.00 16.65 ? 355 VAL A CG2 1 ATOM 2781 N N . ASN A 1 356 ? 32.321 54.328 32.590 1.00 12.43 ? 356 ASN A N 1 ATOM 2782 C CA . ASN A 1 356 ? 30.931 53.911 32.472 1.00 12.19 ? 356 ASN A CA 1 ATOM 2783 C C . ASN A 1 356 ? 30.828 52.624 31.637 1.00 13.35 ? 356 ASN A C 1 ATOM 2784 O O . ASN A 1 356 ? 30.093 51.672 32.026 1.00 12.92 ? 356 ASN A O 1 ATOM 2785 C CB . ASN A 1 356 ? 30.038 55.045 31.992 1.00 13.25 ? 356 ASN A CB 1 ATOM 2786 C CG . ASN A 1 356 ? 29.795 56.039 33.069 1.00 14.36 ? 356 ASN A CG 1 ATOM 2787 O OD1 . ASN A 1 356 ? 29.100 55.725 34.055 1.00 14.75 ? 356 ASN A OD1 1 ATOM 2788 N ND2 . ASN A 1 356 ? 30.389 57.237 32.949 1.00 14.47 ? 356 ASN A ND2 1 ATOM 2789 N N . TYR A 1 357 ? 31.561 52.530 30.531 1.00 11.40 ? 357 TYR A N 1 ATOM 2790 C CA . TYR A 1 357 ? 31.503 51.298 29.789 1.00 11.57 ? 357 TYR A CA 1 ATOM 2791 C C . TYR A 1 357 ? 32.116 50.123 30.547 1.00 11.77 ? 357 TYR A C 1 ATOM 2792 O O . TYR A 1 357 ? 31.572 49.001 30.449 1.00 11.97 ? 357 TYR A O 1 ATOM 2793 C CB . TYR A 1 357 ? 32.131 51.466 28.367 1.00 10.50 ? 357 TYR A CB 1 ATOM 2794 C CG . TYR A 1 357 ? 31.137 51.979 27.389 1.00 10.67 ? 357 TYR A CG 1 ATOM 2795 C CD1 . TYR A 1 357 ? 30.274 51.095 26.693 1.00 10.28 ? 357 TYR A CD1 1 ATOM 2796 C CD2 . TYR A 1 357 ? 30.999 53.350 27.191 1.00 10.17 ? 357 TYR A CD2 1 ATOM 2797 C CE1 . TYR A 1 357 ? 29.305 51.571 25.833 1.00 10.26 ? 357 TYR A CE1 1 ATOM 2798 C CE2 . TYR A 1 357 ? 30.005 53.862 26.332 1.00 10.72 ? 357 TYR A CE2 1 ATOM 2799 C CZ . TYR A 1 357 ? 29.146 52.976 25.646 1.00 11.75 ? 357 TYR A CZ 1 ATOM 2800 O OH . TYR A 1 357 ? 28.146 53.445 24.843 1.00 11.46 ? 357 TYR A OH 1 ATOM 2801 N N . GLU A 1 358 ? 33.212 50.330 31.293 1.00 11.92 ? 358 GLU A N 1 ATOM 2802 C CA . GLU A 1 358 ? 33.762 49.215 32.092 1.00 12.79 ? 358 GLU A CA 1 ATOM 2803 C C . GLU A 1 358 ? 32.688 48.692 33.076 1.00 12.99 ? 358 GLU A C 1 ATOM 2804 O O . GLU A 1 358 ? 32.591 47.481 33.278 1.00 13.03 ? 358 GLU A O 1 ATOM 2805 C CB . GLU A 1 358 ? 34.961 49.664 32.905 1.00 13.78 ? 358 GLU A CB 1 ATOM 2806 C CG . GLU A 1 358 ? 36.236 49.904 32.082 1.00 16.11 ? 358 GLU A CG 1 ATOM 2807 C CD . GLU A 1 358 ? 37.448 50.300 32.928 1.00 18.33 ? 358 GLU A CD 1 ATOM 2808 O OE1 . GLU A 1 358 ? 37.364 50.293 34.173 1.00 21.27 ? 358 GLU A OE1 1 ATOM 2809 O OE2 . GLU A 1 358 ? 38.512 50.603 32.371 1.00 18.33 ? 358 GLU A OE2 1 ATOM 2810 N N . ARG A 1 359 ? 31.904 49.577 33.671 1.00 12.52 ? 359 ARG A N 1 ATOM 2811 C CA . ARG A 1 359 ? 30.873 49.092 34.624 1.00 14.31 ? 359 ARG A CA 1 ATOM 2812 C C . ARG A 1 359 ? 29.804 48.295 33.894 1.00 14.14 ? 359 ARG A C 1 ATOM 2813 O O . ARG A 1 359 ? 29.305 47.263 34.411 1.00 14.00 ? 359 ARG A O 1 ATOM 2814 C CB . ARG A 1 359 ? 30.223 50.246 35.363 1.00 15.39 ? 359 ARG A CB 1 ATOM 2815 C CG . ARG A 1 359 ? 31.089 50.943 36.401 1.00 18.10 ? 359 ARG A CG 1 ATOM 2816 C CD . ARG A 1 359 ? 30.332 52.178 36.877 1.00 21.83 ? 359 ARG A CD 1 ATOM 2817 N NE . ARG A 1 359 ? 31.191 53.105 37.615 1.00 24.87 ? 359 ARG A NE 1 ATOM 2818 C CZ . ARG A 1 359 ? 31.208 54.437 37.438 1.00 25.24 ? 359 ARG A CZ 1 ATOM 2819 N NH1 . ARG A 1 359 ? 30.407 55.062 36.530 1.00 24.06 ? 359 ARG A NH1 1 ATOM 2820 N NH2 . ARG A 1 359 ? 32.048 55.163 38.191 1.00 29.05 ? 359 ARG A NH2 1 ATOM 2821 N N . LEU A 1 360 ? 29.405 48.726 32.702 1.00 13.09 ? 360 LEU A N 1 ATOM 2822 C CA . LEU A 1 360 ? 28.436 47.981 31.927 1.00 12.40 ? 360 LEU A CA 1 ATOM 2823 C C . LEU A 1 360 ? 29.010 46.627 31.536 1.00 12.88 ? 360 LEU A C 1 ATOM 2824 O O . LEU A 1 360 ? 28.315 45.602 31.670 1.00 14.31 ? 360 LEU A O 1 ATOM 2825 C CB . LEU A 1 360 ? 28.064 48.785 30.676 1.00 12.36 ? 360 LEU A CB 1 ATOM 2826 C CG . LEU A 1 360 ? 27.192 50.012 31.011 1.00 11.75 ? 360 LEU A CG 1 ATOM 2827 C CD1 . LEU A 1 360 ? 27.275 51.034 29.868 1.00 13.24 ? 360 LEU A CD1 1 ATOM 2828 C CD2 . LEU A 1 360 ? 25.717 49.628 31.204 1.00 13.43 ? 360 LEU A CD2 1 ATOM 2829 N N . PHE A 1 361 ? 30.247 46.568 31.044 1.00 12.39 ? 361 PHE A N 1 ATOM 2830 C CA . PHE A 1 361 ? 30.837 45.277 30.647 1.00 12.50 ? 361 PHE A CA 1 ATOM 2831 C C . PHE A 1 361 ? 30.935 44.316 31.861 1.00 13.95 ? 361 PHE A C 1 ATOM 2832 O O . PHE A 1 361 ? 30.671 43.117 31.721 1.00 13.60 ? 361 PHE A O 1 ATOM 2833 C CB . PHE A 1 361 ? 32.263 45.440 30.091 1.00 12.10 ? 361 PHE A CB 1 ATOM 2834 C CG . PHE A 1 361 ? 32.349 46.228 28.829 1.00 11.95 ? 361 PHE A CG 1 ATOM 2835 C CD1 . PHE A 1 361 ? 31.269 46.368 27.982 1.00 11.48 ? 361 PHE A CD1 1 ATOM 2836 C CD2 . PHE A 1 361 ? 33.542 46.865 28.549 1.00 11.43 ? 361 PHE A CD2 1 ATOM 2837 C CE1 . PHE A 1 361 ? 31.382 47.172 26.819 1.00 11.79 ? 361 PHE A CE1 1 ATOM 2838 C CE2 . PHE A 1 361 ? 33.667 47.678 27.370 1.00 12.27 ? 361 PHE A CE2 1 ATOM 2839 C CZ . PHE A 1 361 ? 32.582 47.811 26.533 1.00 11.95 ? 361 PHE A CZ 1 ATOM 2840 N N . GLU A 1 362 ? 31.378 44.819 33.020 1.00 14.20 ? 362 GLU A N 1 ATOM 2841 C CA . GLU A 1 362 ? 31.509 43.886 34.146 1.00 14.27 ? 362 GLU A CA 1 ATOM 2842 C C . GLU A 1 362 ? 30.121 43.294 34.499 1.00 13.76 ? 362 GLU A C 1 ATOM 2843 O O . GLU A 1 362 ? 30.003 42.095 34.739 1.00 14.52 ? 362 GLU A O 1 ATOM 2844 C CB . GLU A 1 362 ? 32.113 44.599 35.363 1.00 16.48 ? 362 GLU A CB 1 ATOM 2845 C CG . GLU A 1 362 ? 32.221 43.603 36.499 1.00 19.73 ? 362 GLU A CG 1 ATOM 2846 C CD . GLU A 1 362 ? 32.703 44.177 37.806 1.00 24.12 ? 362 GLU A CD 1 ATOM 2847 O OE1 . GLU A 1 362 ? 33.039 45.387 37.872 1.00 27.03 ? 362 GLU A OE1 1 ATOM 2848 O OE2 . GLU A 1 362 ? 32.722 43.373 38.768 1.00 25.55 ? 362 GLU A OE2 1 ATOM 2849 N N . HIS A 1 363 ? 29.087 44.110 34.514 1.00 13.72 ? 363 HIS A N 1 ATOM 2850 C CA . HIS A 1 363 ? 27.754 43.602 34.801 1.00 15.17 ? 363 HIS A CA 1 ATOM 2851 C C . HIS A 1 363 ? 27.241 42.647 33.734 1.00 14.68 ? 363 HIS A C 1 ATOM 2852 O O . HIS A 1 363 ? 26.865 41.490 34.003 1.00 15.22 ? 363 HIS A O 1 ATOM 2853 C CB . HIS A 1 363 ? 26.749 44.740 34.994 1.00 15.58 ? 363 HIS A CB 1 ATOM 2854 C CG . HIS A 1 363 ? 25.350 44.270 35.310 1.00 17.86 ? 363 HIS A CG 1 ATOM 2855 N ND1 . HIS A 1 363 ? 24.970 43.839 36.573 1.00 19.98 ? 363 HIS A ND1 1 ATOM 2856 C CD2 . HIS A 1 363 ? 24.263 44.129 34.521 1.00 18.73 ? 363 HIS A CD2 1 ATOM 2857 C CE1 . HIS A 1 363 ? 23.707 43.452 36.531 1.00 20.13 ? 363 HIS A CE1 1 ATOM 2858 N NE2 . HIS A 1 363 ? 23.246 43.618 35.306 1.00 20.48 ? 363 HIS A NE2 1 ATOM 2859 N N . ILE A 1 364 ? 27.257 43.094 32.471 1.00 14.17 ? 364 ILE A N 1 ATOM 2860 C CA . ILE A 1 364 ? 26.713 42.297 31.412 1.00 14.26 ? 364 ILE A CA 1 ATOM 2861 C C . ILE A 1 364 ? 27.424 40.977 31.280 1.00 13.32 ? 364 ILE A C 1 ATOM 2862 O O . ILE A 1 364 ? 26.760 39.912 31.149 1.00 14.93 ? 364 ILE A O 1 ATOM 2863 C CB . ILE A 1 364 ? 26.818 43.075 30.050 1.00 13.62 ? 364 ILE A CB 1 ATOM 2864 C CG1 . ILE A 1 364 ? 25.787 44.218 30.028 1.00 13.65 ? 364 ILE A CG1 1 ATOM 2865 C CG2 . ILE A 1 364 ? 26.604 42.094 28.894 1.00 12.80 ? 364 ILE A CG2 1 ATOM 2866 C CD1 . ILE A 1 364 ? 26.079 45.341 29.013 1.00 13.83 ? 364 ILE A CD1 1 ATOM 2867 N N . ASN A 1 365 ? 28.740 40.981 31.324 1.00 13.50 ? 365 ASN A N 1 ATOM 2868 C CA . ASN A 1 365 ? 29.527 39.747 31.105 1.00 14.99 ? 365 ASN A CA 1 ATOM 2869 C C . ASN A 1 365 ? 29.383 38.748 32.259 1.00 16.92 ? 365 ASN A C 1 ATOM 2870 O O . ASN A 1 365 ? 29.701 37.575 32.095 1.00 16.99 ? 365 ASN A O 1 ATOM 2871 C CB . ASN A 1 365 ? 31.009 40.031 30.875 1.00 13.35 ? 365 ASN A CB 1 ATOM 2872 C CG . ASN A 1 365 ? 31.240 40.868 29.602 1.00 12.85 ? 365 ASN A CG 1 ATOM 2873 O OD1 . ASN A 1 365 ? 30.313 41.039 28.806 1.00 13.40 ? 365 ASN A OD1 1 ATOM 2874 N ND2 . ASN A 1 365 ? 32.449 41.399 29.456 1.00 12.50 ? 365 ASN A ND2 1 ATOM 2875 N N . SER A 1 366 ? 28.890 39.240 33.394 1.00 18.53 ? 366 SER A N 1 ATOM 2876 C CA . SER A 1 366 ? 28.736 38.371 34.579 1.00 21.13 ? 366 SER A CA 1 ATOM 2877 C C . SER A 1 366 ? 27.324 37.853 34.747 1.00 21.96 ? 366 SER A C 1 ATOM 2878 O O . SER A 1 366 ? 27.072 36.987 35.601 1.00 23.39 ? 366 SER A O 1 ATOM 2879 C CB . SER A 1 366 ? 29.165 39.136 35.858 1.00 21.56 ? 366 SER A CB 1 ATOM 2880 O OG . SER A 1 366 ? 28.158 40.064 36.238 1.00 24.15 ? 366 SER A OG 1 ATOM 2881 N N . GLN A 1 367 ? 26.394 38.362 33.970 1.00 22.47 ? 367 GLN A N 1 ATOM 2882 C CA . GLN A 1 367 ? 25.002 37.962 34.035 1.00 23.37 ? 367 GLN A CA 1 ATOM 2883 C C . GLN A 1 367 ? 24.696 37.013 32.874 1.00 23.21 ? 367 GLN A C 1 ATOM 2884 O O . GLN A 1 367 ? 24.310 37.427 31.767 1.00 22.26 ? 367 GLN A O 1 ATOM 2885 C CB . GLN A 1 367 ? 24.105 39.180 33.940 1.00 25.23 ? 367 GLN A CB 1 ATOM 2886 C CG . GLN A 1 367 ? 24.214 40.086 35.144 1.00 28.52 ? 367 GLN A CG 1 ATOM 2887 C CD . GLN A 1 367 ? 23.493 39.476 36.319 1.00 30.15 ? 367 GLN A CD 1 ATOM 2888 O OE1 . GLN A 1 367 ? 22.275 39.250 36.249 1.00 31.42 ? 367 GLN A OE1 1 ATOM 2889 N NE2 . GLN A 1 367 ? 24.233 39.188 37.402 1.00 31.06 ? 367 GLN A NE2 1 ATOM 2890 N N . ALA A 1 368 ? 24.779 35.722 33.171 1.00 21.99 ? 368 ALA A N 1 ATOM 2891 C CA . ALA A 1 368 ? 24.557 34.693 32.168 1.00 21.01 ? 368 ALA A CA 1 ATOM 2892 C C . ALA A 1 368 ? 23.311 34.853 31.305 1.00 20.46 ? 368 ALA A C 1 ATOM 2893 O O . ALA A 1 368 ? 23.335 34.520 30.100 1.00 20.06 ? 368 ALA A O 1 ATOM 2894 C CB . ALA A 1 368 ? 24.507 33.331 32.865 1.00 21.78 ? 368 ALA A CB 1 ATOM 2895 N N . HIS A 1 369 ? 22.212 35.328 31.895 1.00 19.32 ? 369 HIS A N 1 ATOM 2896 C CA . HIS A 1 369 ? 20.977 35.478 31.167 1.00 19.69 ? 369 HIS A CA 1 ATOM 2897 C C . HIS A 1 369 ? 21.107 36.357 29.930 1.00 18.84 ? 369 HIS A C 1 ATOM 2898 O O . HIS A 1 369 ? 20.296 36.232 29.029 1.00 19.98 ? 369 HIS A O 1 ATOM 2899 C CB . HIS A 1 369 ? 19.843 35.999 32.084 1.00 21.82 ? 369 HIS A CB 1 ATOM 2900 C CG . HIS A 1 369 ? 20.051 37.398 32.570 1.00 23.42 ? 369 HIS A CG 1 ATOM 2901 N ND1 . HIS A 1 369 ? 19.621 38.501 31.863 1.00 25.66 ? 369 HIS A ND1 1 ATOM 2902 C CD2 . HIS A 1 369 ? 20.698 37.877 33.656 1.00 24.74 ? 369 HIS A CD2 1 ATOM 2903 C CE1 . HIS A 1 369 ? 19.997 39.603 32.490 1.00 24.50 ? 369 HIS A CE1 1 ATOM 2904 N NE2 . HIS A 1 369 ? 20.655 39.254 33.581 1.00 25.28 ? 369 HIS A NE2 1 ATOM 2905 N N . PHE A 1 370 ? 22.111 37.244 29.875 1.00 18.80 ? 370 PHE A N 1 ATOM 2906 C CA . PHE A 1 370 ? 22.242 38.061 28.640 1.00 17.38 ? 370 PHE A CA 1 ATOM 2907 C C . PHE A 1 370 ? 22.920 37.275 27.506 1.00 15.61 ? 370 PHE A C 1 ATOM 2908 O O . PHE A 1 370 ? 22.696 37.574 26.328 1.00 16.03 ? 370 PHE A O 1 ATOM 2909 C CB . PHE A 1 370 ? 23.123 39.307 28.837 1.00 18.64 ? 370 PHE A CB 1 ATOM 2910 C CG . PHE A 1 370 ? 22.514 40.385 29.682 1.00 19.42 ? 370 PHE A CG 1 ATOM 2911 C CD1 . PHE A 1 370 ? 21.349 41.019 29.280 1.00 20.16 ? 370 PHE A CD1 1 ATOM 2912 C CD2 . PHE A 1 370 ? 23.157 40.808 30.824 1.00 20.20 ? 370 PHE A CD2 1 ATOM 2913 C CE1 . PHE A 1 370 ? 20.817 42.115 30.042 1.00 21.51 ? 370 PHE A CE1 1 ATOM 2914 C CE2 . PHE A 1 370 ? 22.643 41.889 31.577 1.00 21.75 ? 370 PHE A CE2 1 ATOM 2915 C CZ . PHE A 1 370 ? 21.496 42.519 31.181 1.00 21.22 ? 370 PHE A CZ 1 ATOM 2916 N N . ASN A 1 371 ? 23.767 36.314 27.875 1.00 14.49 ? 371 ASN A N 1 ATOM 2917 C CA . ASN A 1 371 ? 24.527 35.502 26.939 1.00 13.62 ? 371 ASN A CA 1 ATOM 2918 C C . ASN A 1 371 ? 25.304 36.414 26.004 1.00 13.65 ? 371 ASN A C 1 ATOM 2919 O O . ASN A 1 371 ? 25.308 36.224 24.777 1.00 14.42 ? 371 ASN A O 1 ATOM 2920 C CB . ASN A 1 371 ? 23.596 34.555 26.167 1.00 15.21 ? 371 ASN A CB 1 ATOM 2921 C CG . ASN A 1 371 ? 22.921 33.554 27.096 1.00 15.66 ? 371 ASN A CG 1 ATOM 2922 O OD1 . ASN A 1 371 ? 23.597 32.743 27.746 1.00 17.18 ? 371 ASN A OD1 1 ATOM 2923 N ND2 . ASN A 1 371 ? 21.619 33.651 27.190 1.00 16.95 ? 371 ASN A ND2 1 ATOM 2924 N N . VAL A 1 372 ? 25.973 37.388 26.617 1.00 12.27 ? 372 VAL A N 1 ATOM 2925 C CA . VAL A 1 372 ? 26.810 38.367 25.888 1.00 13.11 ? 372 VAL A CA 1 ATOM 2926 C C . VAL A 1 372 ? 28.179 38.445 26.503 1.00 13.21 ? 372 VAL A C 1 ATOM 2927 O O . VAL A 1 372 ? 28.327 38.334 27.741 1.00 14.23 ? 372 VAL A O 1 ATOM 2928 C CB . VAL A 1 372 ? 26.171 39.794 25.998 1.00 13.34 ? 372 VAL A CB 1 ATOM 2929 C CG1 . VAL A 1 372 ? 27.143 40.927 25.440 1.00 12.99 ? 372 VAL A CG1 1 ATOM 2930 C CG2 . VAL A 1 372 ? 24.838 39.841 25.218 1.00 13.54 ? 372 VAL A CG2 1 ATOM 2931 N N . GLN A 1 373 ? 29.210 38.601 25.678 1.00 12.65 ? 373 GLN A N 1 ATOM 2932 C CA . GLN A 1 373 ? 30.587 38.878 26.138 1.00 12.06 ? 373 GLN A CA 1 ATOM 2933 C C . GLN A 1 373 ? 30.955 40.183 25.395 1.00 11.40 ? 373 GLN A C 1 ATOM 2934 O O . GLN A 1 373 ? 31.137 40.173 24.149 1.00 11.61 ? 373 GLN A O 1 ATOM 2935 C CB . GLN A 1 373 ? 31.563 37.759 25.779 1.00 13.44 ? 373 GLN A CB 1 ATOM 2936 C CG . GLN A 1 373 ? 33.049 38.075 26.104 1.00 15.79 ? 373 GLN A CG 1 ATOM 2937 C CD . GLN A 1 373 ? 33.303 38.443 27.575 1.00 17.38 ? 373 GLN A CD 1 ATOM 2938 O OE1 . GLN A 1 373 ? 32.565 37.990 28.476 1.00 18.88 ? 373 GLN A OE1 1 ATOM 2939 N NE2 . GLN A 1 373 ? 34.333 39.280 27.822 1.00 18.73 ? 373 GLN A NE2 1 ATOM 2940 N N . ALA A 1 374 ? 31.035 41.296 26.112 1.00 11.27 ? 374 ALA A N 1 ATOM 2941 C CA . ALA A 1 374 ? 31.322 42.599 25.526 1.00 11.65 ? 374 ALA A CA 1 ATOM 2942 C C . ALA A 1 374 ? 32.620 43.153 26.000 1.00 11.43 ? 374 ALA A C 1 ATOM 2943 O O . ALA A 1 374 ? 32.998 42.994 27.171 1.00 11.55 ? 374 ALA A O 1 ATOM 2944 C CB . ALA A 1 374 ? 30.191 43.560 25.875 1.00 11.62 ? 374 ALA A CB 1 ATOM 2945 N N . GLN A 1 375 ? 33.330 43.856 25.108 1.00 11.12 ? 375 GLN A N 1 ATOM 2946 C CA . GLN A 1 375 ? 34.629 44.434 25.444 1.00 10.85 ? 375 GLN A CA 1 ATOM 2947 C C . GLN A 1 375 ? 35.038 45.515 24.465 1.00 9.76 ? 375 GLN A C 1 ATOM 2948 O O . GLN A 1 375 ? 34.490 45.591 23.381 1.00 11.07 ? 375 GLN A O 1 ATOM 2949 C CB . GLN A 1 375 ? 35.710 43.363 25.356 1.00 12.10 ? 375 GLN A CB 1 ATOM 2950 C CG . GLN A 1 375 ? 35.723 42.631 23.979 1.00 15.25 ? 375 GLN A CG 1 ATOM 2951 C CD . GLN A 1 375 ? 35.044 41.275 24.082 1.00 18.77 ? 375 GLN A CD 1 ATOM 2952 O OE1 . GLN A 1 375 ? 35.490 40.414 24.869 1.00 21.87 ? 375 GLN A OE1 1 ATOM 2953 N NE2 . GLN A 1 375 ? 33.941 41.074 23.315 1.00 18.46 ? 375 GLN A NE2 1 ATOM 2954 N N . PHE A 1 376 ? 35.969 46.371 24.894 1.00 10.03 ? 376 PHE A N 1 ATOM 2955 C CA . PHE A 1 376 ? 36.548 47.310 23.930 1.00 10.36 ? 376 PHE A CA 1 ATOM 2956 C C . PHE A 1 376 ? 37.357 46.464 22.942 1.00 11.54 ? 376 PHE A C 1 ATOM 2957 O O . PHE A 1 376 ? 37.990 45.464 23.276 1.00 11.79 ? 376 PHE A O 1 ATOM 2958 C CB . PHE A 1 376 ? 37.520 48.260 24.638 1.00 10.13 ? 376 PHE A CB 1 ATOM 2959 C CG . PHE A 1 376 ? 36.844 49.199 25.556 1.00 10.45 ? 376 PHE A CG 1 ATOM 2960 C CD1 . PHE A 1 376 ? 35.823 50.052 25.106 1.00 11.30 ? 376 PHE A CD1 1 ATOM 2961 C CD2 . PHE A 1 376 ? 37.227 49.252 26.910 1.00 12.26 ? 376 PHE A CD2 1 ATOM 2962 C CE1 . PHE A 1 376 ? 35.186 50.960 26.046 1.00 12.59 ? 376 PHE A CE1 1 ATOM 2963 C CE2 . PHE A 1 376 ? 36.585 50.144 27.786 1.00 13.41 ? 376 PHE A CE2 1 ATOM 2964 C CZ . PHE A 1 376 ? 35.602 50.973 27.376 1.00 13.96 ? 376 PHE A CZ 1 ATOM 2965 N N . GLY A 1 377 ? 37.327 46.891 21.667 1.00 10.49 ? 377 GLY A N 1 ATOM 2966 C CA . GLY A 1 377 ? 38.086 46.181 20.665 1.00 10.14 ? 377 GLY A CA 1 ATOM 2967 C C . GLY A 1 377 ? 38.491 47.148 19.566 1.00 9.52 ? 377 GLY A C 1 ATOM 2968 O O . GLY A 1 377 ? 38.188 48.319 19.590 1.00 10.31 ? 377 GLY A O 1 ATOM 2969 N N . THR A 1 378 ? 39.241 46.584 18.619 1.00 11.07 ? 378 THR A N 1 ATOM 2970 C CA . THR A 1 378 ? 39.670 47.344 17.436 1.00 10.86 ? 378 THR A CA 1 ATOM 2971 C C . THR A 1 378 ? 38.917 46.782 16.221 1.00 10.07 ? 378 THR A C 1 ATOM 2972 O O . THR A 1 378 ? 38.210 45.765 16.274 1.00 9.90 ? 378 THR A O 1 ATOM 2973 C CB . THR A 1 378 ? 41.170 47.212 17.156 1.00 11.28 ? 378 THR A CB 1 ATOM 2974 O OG1 . THR A 1 378 ? 41.481 45.859 16.804 1.00 11.79 ? 378 THR A OG1 1 ATOM 2975 C CG2 . THR A 1 378 ? 42.018 47.594 18.396 1.00 13.23 ? 378 THR A CG2 1 ATOM 2976 N N . LEU A 1 379 ? 39.071 47.459 15.080 1.00 9.55 ? 379 LEU A N 1 ATOM 2977 C CA . LEU A 1 379 ? 38.399 47.038 13.854 1.00 9.02 ? 379 LEU A CA 1 ATOM 2978 C C . LEU A 1 379 ? 38.896 45.708 13.367 1.00 8.45 ? 379 LEU A C 1 ATOM 2979 O O . LEU A 1 379 ? 38.115 44.833 13.004 1.00 9.16 ? 379 LEU A O 1 ATOM 2980 C CB . LEU A 1 379 ? 38.598 48.140 12.804 1.00 9.35 ? 379 LEU A CB 1 ATOM 2981 C CG . LEU A 1 379 ? 37.848 47.899 11.496 1.00 9.27 ? 379 LEU A CG 1 ATOM 2982 C CD1 . LEU A 1 379 ? 36.298 47.926 11.764 1.00 9.70 ? 379 LEU A CD1 1 ATOM 2983 C CD2 . LEU A 1 379 ? 38.260 49.032 10.486 1.00 9.62 ? 379 LEU A CD2 1 ATOM 2984 N N . GLN A 1 380 ? 40.222 45.510 13.400 1.00 8.69 ? 380 GLN A N 1 ATOM 2985 C CA . GLN A 1 380 ? 40.784 44.221 12.948 1.00 9.82 ? 380 GLN A CA 1 ATOM 2986 C C . GLN A 1 380 ? 40.272 43.091 13.850 1.00 10.33 ? 380 GLN A C 1 ATOM 2987 O O . GLN A 1 380 ? 40.012 41.984 13.357 1.00 9.85 ? 380 GLN A O 1 ATOM 2988 C CB . GLN A 1 380 ? 42.312 44.275 12.955 1.00 10.98 ? 380 GLN A CB 1 ATOM 2989 C CG . GLN A 1 380 ? 42.923 42.956 12.425 1.00 12.54 ? 380 GLN A CG 1 ATOM 2990 C CD . GLN A 1 380 ? 42.636 42.803 10.964 1.00 14.16 ? 380 GLN A CD 1 ATOM 2991 O OE1 . GLN A 1 380 ? 42.695 43.789 10.200 1.00 14.69 ? 380 GLN A OE1 1 ATOM 2992 N NE2 . GLN A 1 380 ? 42.320 41.557 10.532 1.00 17.65 ? 380 GLN A NE2 1 ATOM 2993 N N . GLU A 1 381 ? 40.123 43.362 15.149 1.00 10.55 ? 381 GLU A N 1 ATOM 2994 C CA . GLU A 1 381 ? 39.641 42.310 16.040 1.00 10.42 ? 381 GLU A CA 1 ATOM 2995 C C . GLU A 1 381 ? 38.215 41.895 15.656 1.00 9.46 ? 381 GLU A C 1 ATOM 2996 O O . GLU A 1 381 ? 37.885 40.719 15.669 1.00 11.11 ? 381 GLU A O 1 ATOM 2997 C CB . GLU A 1 381 ? 39.623 42.800 17.486 1.00 12.16 ? 381 GLU A CB 1 ATOM 2998 C CG . GLU A 1 381 ? 40.927 42.813 18.276 1.00 17.06 ? 381 GLU A CG 1 ATOM 2999 C CD . GLU A 1 381 ? 40.538 43.132 19.737 1.00 19.57 ? 381 GLU A CD 1 ATOM 3000 O OE1 . GLU A 1 381 ? 40.359 44.285 20.019 1.00 20.09 ? 381 GLU A OE1 1 ATOM 3001 O OE2 . GLU A 1 381 ? 40.345 42.213 20.608 1.00 23.53 ? 381 GLU A OE2 1 ATOM 3002 N N . TYR A 1 382 ? 37.370 42.864 15.306 1.00 9.85 ? 382 TYR A N 1 ATOM 3003 C CA . TYR A 1 382 ? 36.044 42.551 14.871 1.00 8.76 ? 382 TYR A CA 1 ATOM 3004 C C . TYR A 1 382 ? 36.096 41.656 13.629 1.00 8.80 ? 382 TYR A C 1 ATOM 3005 O O . TYR A 1 382 ? 35.448 40.616 13.553 1.00 9.56 ? 382 TYR A O 1 ATOM 3006 C CB . TYR A 1 382 ? 35.276 43.834 14.507 1.00 9.07 ? 382 TYR A CB 1 ATOM 3007 C CG . TYR A 1 382 ? 33.952 43.552 13.818 1.00 8.76 ? 382 TYR A CG 1 ATOM 3008 C CD1 . TYR A 1 382 ? 32.881 42.959 14.506 1.00 9.34 ? 382 TYR A CD1 1 ATOM 3009 C CD2 . TYR A 1 382 ? 33.795 43.813 12.438 1.00 9.26 ? 382 TYR A CD2 1 ATOM 3010 C CE1 . TYR A 1 382 ? 31.694 42.633 13.850 1.00 9.87 ? 382 TYR A CE1 1 ATOM 3011 C CE2 . TYR A 1 382 ? 32.631 43.490 11.798 1.00 9.65 ? 382 TYR A CE2 1 ATOM 3012 C CZ . TYR A 1 382 ? 31.584 42.891 12.510 1.00 9.15 ? 382 TYR A CZ 1 ATOM 3013 O OH . TYR A 1 382 ? 30.405 42.516 11.889 1.00 10.09 ? 382 TYR A OH 1 ATOM 3014 N N . PHE A 1 383 ? 36.792 42.118 12.593 1.00 8.72 ? 383 PHE A N 1 ATOM 3015 C CA . PHE A 1 383 ? 36.839 41.316 11.373 1.00 8.93 ? 383 PHE A CA 1 ATOM 3016 C C . PHE A 1 383 ? 37.447 39.930 11.582 1.00 9.18 ? 383 PHE A C 1 ATOM 3017 O O . PHE A 1 383 ? 36.947 38.958 11.004 1.00 10.97 ? 383 PHE A O 1 ATOM 3018 C CB . PHE A 1 383 ? 37.616 42.070 10.258 1.00 8.56 ? 383 PHE A CB 1 ATOM 3019 C CG . PHE A 1 383 ? 36.841 43.220 9.641 1.00 8.90 ? 383 PHE A CG 1 ATOM 3020 C CD1 . PHE A 1 383 ? 35.615 43.002 8.990 1.00 8.81 ? 383 PHE A CD1 1 ATOM 3021 C CD2 . PHE A 1 383 ? 37.390 44.522 9.676 1.00 9.04 ? 383 PHE A CD2 1 ATOM 3022 C CE1 . PHE A 1 383 ? 34.920 44.079 8.364 1.00 9.56 ? 383 PHE A CE1 1 ATOM 3023 C CE2 . PHE A 1 383 ? 36.701 45.594 9.053 1.00 8.64 ? 383 PHE A CE2 1 ATOM 3024 C CZ . PHE A 1 383 ? 35.484 45.365 8.408 1.00 9.08 ? 383 PHE A CZ 1 ATOM 3025 N N . ASP A 1 384 ? 38.487 39.834 12.412 1.00 10.72 ? 384 ASP A N 1 ATOM 3026 C CA . ASP A 1 384 ? 39.073 38.502 12.640 1.00 11.81 ? 384 ASP A CA 1 ATOM 3027 C C . ASP A 1 384 ? 38.013 37.575 13.281 1.00 11.35 ? 384 ASP A C 1 ATOM 3028 O O . ASP A 1 384 ? 37.908 36.381 12.903 1.00 12.02 ? 384 ASP A O 1 ATOM 3029 C CB . ASP A 1 384 ? 40.276 38.582 13.580 1.00 12.92 ? 384 ASP A CB 1 ATOM 3030 C CG . ASP A 1 384 ? 41.495 39.196 12.952 1.00 15.18 ? 384 ASP A CG 1 ATOM 3031 O OD1 . ASP A 1 384 ? 41.607 39.288 11.703 1.00 15.86 ? 384 ASP A OD1 1 ATOM 3032 O OD2 . ASP A 1 384 ? 42.356 39.563 13.795 1.00 17.79 ? 384 ASP A OD2 1 ATOM 3033 N N . ALA A 1 385 ? 37.197 38.093 14.193 1.00 10.80 ? 385 ALA A N 1 ATOM 3034 C CA . ALA A 1 385 ? 36.193 37.267 14.821 1.00 11.43 ? 385 ALA A CA 1 ATOM 3035 C C . ALA A 1 385 ? 35.082 36.937 13.845 1.00 12.00 ? 385 ALA A C 1 ATOM 3036 O O . ALA A 1 385 ? 34.571 35.823 13.857 1.00 12.01 ? 385 ALA A O 1 ATOM 3037 C CB . ALA A 1 385 ? 35.675 37.969 16.093 1.00 11.40 ? 385 ALA A CB 1 ATOM 3038 N N . VAL A 1 386 ? 34.711 37.863 12.951 1.00 10.84 ? 386 VAL A N 1 ATOM 3039 C CA . VAL A 1 386 ? 33.674 37.538 11.985 1.00 11.09 ? 386 VAL A CA 1 ATOM 3040 C C . VAL A 1 386 ? 34.163 36.405 11.078 1.00 11.71 ? 386 VAL A C 1 ATOM 3041 O O . VAL A 1 386 ? 33.387 35.471 10.787 1.00 12.12 ? 386 VAL A O 1 ATOM 3042 C CB . VAL A 1 386 ? 33.379 38.776 11.106 1.00 9.77 ? 386 VAL A CB 1 ATOM 3043 C CG1 . VAL A 1 386 ? 32.543 38.403 9.879 1.00 12.14 ? 386 VAL A CG1 1 ATOM 3044 C CG2 . VAL A 1 386 ? 32.629 39.806 11.934 1.00 12.24 ? 386 VAL A CG2 1 ATOM 3045 N N . HIS A 1 387 ? 35.410 36.457 10.635 1.00 11.71 ? 387 HIS A N 1 ATOM 3046 C CA . HIS A 1 387 ? 35.895 35.402 9.739 1.00 12.93 ? 387 HIS A CA 1 ATOM 3047 C C . HIS A 1 387 ? 36.112 34.065 10.459 1.00 13.36 ? 387 HIS A C 1 ATOM 3048 O O . HIS A 1 387 ? 35.984 33.006 9.822 1.00 13.97 ? 387 HIS A O 1 ATOM 3049 C CB . HIS A 1 387 ? 37.141 35.856 8.972 1.00 12.88 ? 387 HIS A CB 1 ATOM 3050 C CG . HIS A 1 387 ? 36.844 36.966 7.995 1.00 11.95 ? 387 HIS A CG 1 ATOM 3051 N ND1 . HIS A 1 387 ? 35.939 36.820 6.957 1.00 13.94 ? 387 HIS A ND1 1 ATOM 3052 C CD2 . HIS A 1 387 ? 37.274 38.250 7.950 1.00 12.51 ? 387 HIS A CD2 1 ATOM 3053 C CE1 . HIS A 1 387 ? 35.836 37.977 6.308 1.00 14.75 ? 387 HIS A CE1 1 ATOM 3054 N NE2 . HIS A 1 387 ? 36.640 38.856 6.890 1.00 12.52 ? 387 HIS A NE2 1 ATOM 3055 N N . GLN A 1 388 ? 36.379 34.122 11.766 1.00 13.62 ? 388 GLN A N 1 ATOM 3056 C CA . GLN A 1 388 ? 36.483 32.852 12.534 1.00 14.74 ? 388 GLN A CA 1 ATOM 3057 C C . GLN A 1 388 ? 35.081 32.227 12.532 1.00 15.83 ? 388 GLN A C 1 ATOM 3058 O O . GLN A 1 388 ? 34.951 31.014 12.379 1.00 16.28 ? 388 GLN A O 1 ATOM 3059 C CB . GLN A 1 388 ? 36.993 33.169 13.927 1.00 16.20 ? 388 GLN A CB 1 ATOM 3060 C CG . GLN A 1 388 ? 38.517 33.435 13.928 1.00 21.20 ? 388 GLN A CG 1 ATOM 3061 C CD . GLN A 1 388 ? 39.023 34.251 15.167 1.00 24.91 ? 388 GLN A CD 1 ATOM 3062 O OE1 . GLN A 1 388 ? 40.222 34.631 15.256 1.00 27.34 ? 388 GLN A OE1 1 ATOM 3063 N NE2 . GLN A 1 388 ? 38.114 34.523 16.114 1.00 26.28 ? 388 GLN A NE2 1 ATOM 3064 N N . ALA A 1 389 ? 34.029 33.026 12.675 1.00 15.74 ? 389 ALA A N 1 ATOM 3065 C CA . ALA A 1 389 ? 32.634 32.537 12.680 1.00 16.93 ? 389 ALA A CA 1 ATOM 3066 C C . ALA A 1 389 ? 32.322 31.932 11.319 1.00 18.21 ? 389 ALA A C 1 ATOM 3067 O O . ALA A 1 389 ? 31.748 30.840 11.210 1.00 18.76 ? 389 ALA A O 1 ATOM 3068 C CB . ALA A 1 389 ? 31.679 33.685 12.999 1.00 16.48 ? 389 ALA A CB 1 ATOM 3069 N N . GLU A 1 390 ? 32.695 32.636 10.261 1.00 18.22 ? 390 GLU A N 1 ATOM 3070 C CA . GLU A 1 390 ? 32.495 32.165 8.901 1.00 20.20 ? 390 GLU A CA 1 ATOM 3071 C C . GLU A 1 390 ? 33.177 30.808 8.708 1.00 21.10 ? 390 GLU A C 1 ATOM 3072 O O . GLU A 1 390 ? 32.549 29.872 8.180 1.00 21.88 ? 390 GLU A O 1 ATOM 3073 C CB . GLU A 1 390 ? 33.080 33.202 7.932 1.00 19.62 ? 390 GLU A CB 1 ATOM 3074 C CG . GLU A 1 390 ? 33.024 32.874 6.436 1.00 21.69 ? 390 GLU A CG 1 ATOM 3075 C CD . GLU A 1 390 ? 33.755 33.926 5.606 1.00 22.57 ? 390 GLU A CD 1 ATOM 3076 O OE1 . GLU A 1 390 ? 34.603 34.653 6.172 1.00 22.32 ? 390 GLU A OE1 1 ATOM 3077 O OE2 . GLU A 1 390 ? 33.504 34.028 4.383 1.00 24.83 ? 390 GLU A OE2 1 ATOM 3078 N N . ARG A 1 391 ? 34.436 30.691 9.123 1.00 21.89 ? 391 ARG A N 1 ATOM 3079 C CA . ARG A 1 391 ? 35.165 29.428 8.958 1.00 23.51 ? 391 ARG A CA 1 ATOM 3080 C C . ARG A 1 391 ? 34.527 28.311 9.780 1.00 23.35 ? 391 ARG A C 1 ATOM 3081 O O . ARG A 1 391 ? 34.594 27.130 9.383 1.00 24.32 ? 391 ARG A O 1 ATOM 3082 C CB . ARG A 1 391 ? 36.638 29.589 9.335 1.00 24.27 ? 391 ARG A CB 1 ATOM 3083 C CG . ARG A 1 391 ? 37.417 30.458 8.338 1.00 27.36 ? 391 ARG A CG 1 ATOM 3084 C CD . ARG A 1 391 ? 38.926 30.332 8.534 1.00 28.49 ? 391 ARG A CD 1 ATOM 3085 N NE . ARG A 1 391 ? 39.373 30.810 9.842 1.00 30.80 ? 391 ARG A NE 1 ATOM 3086 C CZ . ARG A 1 391 ? 39.562 32.094 10.157 1.00 31.23 ? 391 ARG A CZ 1 ATOM 3087 N NH1 . ARG A 1 391 ? 39.343 33.051 9.260 1.00 31.36 ? 391 ARG A NH1 1 ATOM 3088 N NH2 . ARG A 1 391 ? 39.972 32.409 11.375 1.00 32.33 ? 391 ARG A NH2 1 ATOM 3089 N N . ALA A 1 392 ? 33.879 28.668 10.883 1.00 23.55 ? 392 ALA A N 1 ATOM 3090 C CA . ALA A 1 392 ? 33.212 27.669 11.733 1.00 24.03 ? 392 ALA A CA 1 ATOM 3091 C C . ALA A 1 392 ? 31.877 27.260 11.081 1.00 24.87 ? 392 ALA A C 1 ATOM 3092 O O . ALA A 1 392 ? 31.073 26.505 11.691 1.00 26.58 ? 392 ALA A O 1 ATOM 3093 C CB . ALA A 1 392 ? 32.960 28.242 13.118 1.00 24.01 ? 392 ALA A CB 1 ATOM 3094 N N . GLY A 1 393 ? 31.620 27.776 9.873 1.00 24.89 ? 393 GLY A N 1 ATOM 3095 C CA . GLY A 1 393 ? 30.391 27.453 9.166 1.00 24.23 ? 393 GLY A CA 1 ATOM 3096 C C . GLY A 1 393 ? 29.160 28.150 9.669 1.00 23.73 ? 393 GLY A C 1 ATOM 3097 O O . GLY A 1 393 ? 28.042 27.761 9.339 1.00 24.33 ? 393 GLY A O 1 ATOM 3098 N N . GLN A 1 394 ? 29.326 29.228 10.431 1.00 23.27 ? 394 GLN A N 1 ATOM 3099 C CA . GLN A 1 394 ? 28.132 29.855 10.940 1.00 23.89 ? 394 GLN A CA 1 ATOM 3100 C C . GLN A 1 394 ? 27.497 30.896 10.024 1.00 22.54 ? 394 GLN A C 1 ATOM 3101 O O . GLN A 1 394 ? 26.359 31.328 10.273 1.00 23.94 ? 394 GLN A O 1 ATOM 3102 C CB . GLN A 1 394 ? 28.365 30.351 12.387 1.00 25.90 ? 394 GLN A CB 1 ATOM 3103 C CG . GLN A 1 394 ? 28.934 31.699 12.569 1.00 28.17 ? 394 GLN A CG 1 ATOM 3104 C CD . GLN A 1 394 ? 28.732 32.204 14.008 1.00 27.79 ? 394 GLN A CD 1 ATOM 3105 O OE1 . GLN A 1 394 ? 29.232 31.615 14.993 1.00 28.28 ? 394 GLN A OE1 1 ATOM 3106 N NE2 . GLN A 1 394 ? 28.014 33.285 14.127 1.00 25.02 ? 394 GLN A NE2 1 ATOM 3107 N N . ALA A 1 395 ? 28.169 31.258 8.916 1.00 20.96 ? 395 ALA A N 1 ATOM 3108 C CA . ALA A 1 395 ? 27.593 32.241 7.993 1.00 20.42 ? 395 ALA A CA 1 ATOM 3109 C C . ALA A 1 395 ? 28.265 32.138 6.621 1.00 19.87 ? 395 ALA A C 1 ATOM 3110 O O . ALA A 1 395 ? 29.405 31.696 6.514 1.00 19.88 ? 395 ALA A O 1 ATOM 3111 C CB . ALA A 1 395 ? 27.817 33.676 8.576 1.00 21.49 ? 395 ALA A CB 1 ATOM 3112 N N . GLU A 1 396 ? 27.543 32.506 5.574 1.00 19.72 ? 396 GLU A N 1 ATOM 3113 C CA . GLU A 1 396 ? 28.105 32.563 4.226 1.00 20.30 ? 396 GLU A CA 1 ATOM 3114 C C . GLU A 1 396 ? 27.698 33.987 3.816 1.00 18.80 ? 396 GLU A C 1 ATOM 3115 O O . GLU A 1 396 ? 26.597 34.472 4.171 1.00 19.43 ? 396 GLU A O 1 ATOM 3116 C CB . GLU A 1 396 ? 27.490 31.518 3.293 1.00 24.33 ? 396 GLU A CB 1 ATOM 3117 C CG . GLU A 1 396 ? 26.014 31.708 3.087 1.00 30.12 ? 396 GLU A CG 1 ATOM 3118 C CD . GLU A 1 396 ? 25.302 30.429 2.662 1.00 33.57 ? 396 GLU A CD 1 ATOM 3119 O OE1 . GLU A 1 396 ? 25.646 29.876 1.584 1.00 35.92 ? 396 GLU A OE1 1 ATOM 3120 O OE2 . GLU A 1 396 ? 24.393 29.979 3.414 1.00 36.80 ? 396 GLU A OE2 1 ATOM 3121 N N . PHE A 1 397 ? 28.582 34.650 3.095 1.00 15.24 ? 397 PHE A N 1 ATOM 3122 C CA . PHE A 1 397 ? 28.317 36.030 2.741 1.00 13.17 ? 397 PHE A CA 1 ATOM 3123 C C . PHE A 1 397 ? 27.998 36.193 1.256 1.00 11.45 ? 397 PHE A C 1 ATOM 3124 O O . PHE A 1 397 ? 28.558 35.481 0.423 1.00 13.61 ? 397 PHE A O 1 ATOM 3125 C CB . PHE A 1 397 ? 29.555 36.844 3.104 1.00 12.61 ? 397 PHE A CB 1 ATOM 3126 C CG . PHE A 1 397 ? 29.813 36.913 4.588 1.00 11.57 ? 397 PHE A CG 1 ATOM 3127 C CD1 . PHE A 1 397 ? 28.947 37.637 5.409 1.00 10.73 ? 397 PHE A CD1 1 ATOM 3128 C CD2 . PHE A 1 397 ? 30.888 36.230 5.146 1.00 13.04 ? 397 PHE A CD2 1 ATOM 3129 C CE1 . PHE A 1 397 ? 29.142 37.674 6.781 1.00 11.52 ? 397 PHE A CE1 1 ATOM 3130 C CE2 . PHE A 1 397 ? 31.089 36.261 6.560 1.00 13.61 ? 397 PHE A CE2 1 ATOM 3131 C CZ . PHE A 1 397 ? 30.207 36.984 7.342 1.00 12.38 ? 397 PHE A CZ 1 ATOM 3132 N N . PRO A 1 398 ? 27.083 37.102 0.952 1.00 10.55 ? 398 PRO A N 1 ATOM 3133 C CA . PRO A 1 398 ? 26.698 37.353 -0.442 1.00 11.08 ? 398 PRO A CA 1 ATOM 3134 C C . PRO A 1 398 ? 27.771 38.133 -1.198 1.00 10.05 ? 398 PRO A C 1 ATOM 3135 O O . PRO A 1 398 ? 28.599 38.821 -0.579 1.00 10.10 ? 398 PRO A O 1 ATOM 3136 C CB . PRO A 1 398 ? 25.417 38.167 -0.290 1.00 12.52 ? 398 PRO A CB 1 ATOM 3137 C CG . PRO A 1 398 ? 25.724 39.024 0.982 1.00 11.72 ? 398 PRO A CG 1 ATOM 3138 C CD . PRO A 1 398 ? 26.315 37.940 1.887 1.00 11.14 ? 398 PRO A CD 1 ATOM 3139 N N . THR A 1 399 ? 27.747 38.005 -2.517 1.00 9.84 ? 399 THR A N 1 ATOM 3140 C CA . THR A 1 399 ? 28.639 38.748 -3.399 1.00 9.32 ? 399 THR A CA 1 ATOM 3141 C C . THR A 1 399 ? 27.837 39.971 -3.905 1.00 9.46 ? 399 THR A C 1 ATOM 3142 O O . THR A 1 399 ? 26.615 39.962 -4.062 1.00 9.60 ? 399 THR A O 1 ATOM 3143 C CB . THR A 1 399 ? 29.046 37.883 -4.597 1.00 9.37 ? 399 THR A CB 1 ATOM 3144 O OG1 . THR A 1 399 ? 27.858 37.438 -5.269 1.00 10.92 ? 399 THR A OG1 1 ATOM 3145 C CG2 . THR A 1 399 ? 29.836 36.669 -4.101 1.00 11.74 ? 399 THR A CG2 1 ATOM 3146 N N . LEU A 1 400 ? 28.585 41.050 -4.156 1.00 8.31 ? 400 LEU A N 1 ATOM 3147 C CA . LEU A 1 400 ? 27.991 42.290 -4.608 1.00 7.92 ? 400 LEU A CA 1 ATOM 3148 C C . LEU A 1 400 ? 28.903 43.012 -5.568 1.00 7.56 ? 400 LEU A C 1 ATOM 3149 O O . LEU A 1 400 ? 30.138 43.002 -5.454 1.00 8.26 ? 400 LEU A O 1 ATOM 3150 C CB . LEU A 1 400 ? 27.751 43.199 -3.375 1.00 8.53 ? 400 LEU A CB 1 ATOM 3151 C CG . LEU A 1 400 ? 27.038 44.561 -3.632 1.00 8.45 ? 400 LEU A CG 1 ATOM 3152 C CD1 . LEU A 1 400 ? 26.213 44.909 -2.357 1.00 10.10 ? 400 LEU A CD1 1 ATOM 3153 C CD2 . LEU A 1 400 ? 28.063 45.692 -3.911 1.00 9.44 ? 400 LEU A CD2 1 ATOM 3154 N N . SER A 1 401 ? 28.283 43.648 -6.564 1.00 7.61 ? 401 SER A N 1 ATOM 3155 C CA . SER A 1 401 ? 29.047 44.573 -7.422 1.00 7.92 ? 401 SER A CA 1 ATOM 3156 C C . SER A 1 401 ? 28.183 45.822 -7.606 1.00 7.60 ? 401 SER A C 1 ATOM 3157 O O . SER A 1 401 ? 26.946 45.814 -7.409 1.00 7.44 ? 401 SER A O 1 ATOM 3158 C CB . SER A 1 401 ? 29.423 43.984 -8.787 1.00 8.16 ? 401 SER A CB 1 ATOM 3159 O OG . SER A 1 401 ? 28.315 43.948 -9.686 1.00 8.67 ? 401 SER A OG 1 ATOM 3160 N N . GLY A 1 402 ? 28.864 46.913 -7.965 1.00 7.29 ? 402 GLY A N 1 ATOM 3161 C CA . GLY A 1 402 ? 28.207 48.194 -8.205 1.00 7.84 ? 402 GLY A CA 1 ATOM 3162 C C . GLY A 1 402 ? 28.818 49.286 -7.334 1.00 7.01 ? 402 GLY A C 1 ATOM 3163 O O . GLY A 1 402 ? 29.872 49.087 -6.715 1.00 8.72 ? 402 GLY A O 1 ATOM 3164 N N . ASP A 1 403 ? 28.162 50.431 -7.304 1.00 7.25 ? 403 ASP A N 1 ATOM 3165 C CA . ASP A 1 403 ? 28.647 51.571 -6.475 1.00 7.71 ? 403 ASP A CA 1 ATOM 3166 C C . ASP A 1 403 ? 27.530 52.033 -5.564 1.00 7.07 ? 403 ASP A C 1 ATOM 3167 O O . ASP A 1 403 ? 26.450 51.455 -5.530 1.00 8.18 ? 403 ASP A O 1 ATOM 3168 C CB . ASP A 1 403 ? 29.166 52.723 -7.360 1.00 7.53 ? 403 ASP A CB 1 ATOM 3169 C CG . ASP A 1 403 ? 28.059 53.505 -8.043 1.00 8.46 ? 403 ASP A CG 1 ATOM 3170 O OD1 . ASP A 1 403 ? 26.918 53.037 -8.096 1.00 11.45 ? 403 ASP A OD1 1 ATOM 3171 O OD2 . ASP A 1 403 ? 28.390 54.597 -8.516 1.00 10.96 ? 403 ASP A OD2 1 ATOM 3172 N N . PHE A 1 404 ? 27.816 53.035 -4.756 1.00 6.63 ? 404 PHE A N 1 ATOM 3173 C CA . PHE A 1 404 ? 26.876 53.605 -3.803 1.00 6.70 ? 404 PHE A CA 1 ATOM 3174 C C . PHE A 1 404 ? 26.777 55.105 -3.966 1.00 6.85 ? 404 PHE A C 1 ATOM 3175 O O . PHE A 1 404 ? 26.896 55.886 -3.006 1.00 7.80 ? 404 PHE A O 1 ATOM 3176 C CB . PHE A 1 404 ? 27.234 53.211 -2.352 1.00 7.21 ? 404 PHE A CB 1 ATOM 3177 C CG . PHE A 1 404 ? 27.213 51.726 -2.133 1.00 7.35 ? 404 PHE A CG 1 ATOM 3178 C CD1 . PHE A 1 404 ? 25.982 51.051 -1.996 1.00 8.06 ? 404 PHE A CD1 1 ATOM 3179 C CD2 . PHE A 1 404 ? 28.399 50.993 -2.125 1.00 6.99 ? 404 PHE A CD2 1 ATOM 3180 C CE1 . PHE A 1 404 ? 25.945 49.620 -1.858 1.00 7.87 ? 404 PHE A CE1 1 ATOM 3181 C CE2 . PHE A 1 404 ? 28.367 49.586 -1.988 1.00 7.97 ? 404 PHE A CE2 1 ATOM 3182 C CZ . PHE A 1 404 ? 27.121 48.902 -1.863 1.00 7.99 ? 404 PHE A CZ 1 ATOM 3183 N N . PHE A 1 405 ? 26.529 55.495 -5.206 1.00 7.76 ? 405 PHE A N 1 ATOM 3184 C CA . PHE A 1 405 ? 26.210 56.887 -5.535 1.00 6.09 ? 405 PHE A CA 1 ATOM 3185 C C . PHE A 1 405 ? 24.838 56.856 -6.225 1.00 8.12 ? 405 PHE A C 1 ATOM 3186 O O . PHE A 1 405 ? 24.501 55.881 -6.911 1.00 8.94 ? 405 PHE A O 1 ATOM 3187 C CB . PHE A 1 405 ? 27.230 57.474 -6.540 1.00 7.60 ? 405 PHE A CB 1 ATOM 3188 C CG . PHE A 1 405 ? 28.600 57.598 -5.985 1.00 7.51 ? 405 PHE A CG 1 ATOM 3189 C CD1 . PHE A 1 405 ? 28.838 58.450 -4.894 1.00 7.75 ? 405 PHE A CD1 1 ATOM 3190 C CD2 . PHE A 1 405 ? 29.645 56.893 -6.557 1.00 7.89 ? 405 PHE A CD2 1 ATOM 3191 C CE1 . PHE A 1 405 ? 30.166 58.582 -4.354 1.00 7.73 ? 405 PHE A CE1 1 ATOM 3192 C CE2 . PHE A 1 405 ? 30.953 57.003 -6.036 1.00 8.09 ? 405 PHE A CE2 1 ATOM 3193 C CZ . PHE A 1 405 ? 31.189 57.853 -4.920 1.00 7.30 ? 405 PHE A CZ 1 ATOM 3194 N N . THR A 1 406 ? 24.019 57.893 -6.112 1.00 7.28 ? 406 THR A N 1 ATOM 3195 C CA . THR A 1 406 ? 24.218 59.087 -5.315 1.00 7.22 ? 406 THR A CA 1 ATOM 3196 C C . THR A 1 406 ? 23.562 58.966 -3.964 1.00 7.46 ? 406 THR A C 1 ATOM 3197 O O . THR A 1 406 ? 22.376 58.587 -3.817 1.00 8.58 ? 406 THR A O 1 ATOM 3198 C CB . THR A 1 406 ? 23.683 60.304 -6.120 1.00 7.32 ? 406 THR A CB 1 ATOM 3199 O OG1 . THR A 1 406 ? 24.624 60.528 -7.170 1.00 8.08 ? 406 THR A OG1 1 ATOM 3200 C CG2 . THR A 1 406 ? 23.568 61.586 -5.291 1.00 8.51 ? 406 THR A CG2 1 ATOM 3201 N N . TYR A 1 407 ? 24.346 59.288 -2.950 1.00 7.66 ? 407 TYR A N 1 ATOM 3202 C CA . TYR A 1 407 ? 23.916 59.219 -1.571 1.00 7.21 ? 407 TYR A CA 1 ATOM 3203 C C . TYR A 1 407 ? 22.833 60.199 -1.196 1.00 7.77 ? 407 TYR A C 1 ATOM 3204 O O . TYR A 1 407 ? 22.853 61.346 -1.617 1.00 8.05 ? 407 TYR A O 1 ATOM 3205 C CB . TYR A 1 407 ? 25.162 59.530 -0.690 1.00 8.31 ? 407 TYR A CB 1 ATOM 3206 C CG . TYR A 1 407 ? 24.919 59.662 0.784 1.00 7.22 ? 407 TYR A CG 1 ATOM 3207 C CD1 . TYR A 1 407 ? 24.438 58.575 1.555 1.00 8.40 ? 407 TYR A CD1 1 ATOM 3208 C CD2 . TYR A 1 407 ? 25.252 60.833 1.444 1.00 7.63 ? 407 TYR A CD2 1 ATOM 3209 C CE1 . TYR A 1 407 ? 24.330 58.689 2.937 1.00 7.94 ? 407 TYR A CE1 1 ATOM 3210 C CE2 . TYR A 1 407 ? 25.147 60.966 2.822 1.00 7.81 ? 407 TYR A CE2 1 ATOM 3211 C CZ . TYR A 1 407 ? 24.697 59.884 3.574 1.00 8.41 ? 407 TYR A CZ 1 ATOM 3212 O OH . TYR A 1 407 ? 24.705 59.990 4.951 1.00 8.56 ? 407 TYR A OH 1 ATOM 3213 N N . ALA A 1 408 ? 21.864 59.708 -0.418 1.00 8.32 ? 408 ALA A N 1 ATOM 3214 C CA . ALA A 1 408 ? 20.904 60.599 0.269 1.00 8.64 ? 408 ALA A CA 1 ATOM 3215 C C . ALA A 1 408 ? 20.842 60.126 1.704 1.00 8.67 ? 408 ALA A C 1 ATOM 3216 O O . ALA A 1 408 ? 20.707 58.898 1.972 1.00 8.87 ? 408 ALA A O 1 ATOM 3217 C CB . ALA A 1 408 ? 19.475 60.550 -0.356 1.00 9.84 ? 408 ALA A CB 1 ATOM 3218 N N . ASP A 1 409 ? 20.953 61.072 2.651 1.00 8.26 ? 409 ASP A N 1 ATOM 3219 C CA . ASP A 1 409 ? 20.877 60.702 4.052 1.00 9.21 ? 409 ASP A CA 1 ATOM 3220 C C . ASP A 1 409 ? 19.448 60.769 4.591 1.00 9.78 ? 409 ASP A C 1 ATOM 3221 O O . ASP A 1 409 ? 19.181 60.163 5.634 1.00 10.81 ? 409 ASP A O 1 ATOM 3222 C CB . ASP A 1 409 ? 21.832 61.562 4.934 1.00 9.19 ? 409 ASP A CB 1 ATOM 3223 C CG . ASP A 1 409 ? 21.599 63.074 4.842 1.00 8.39 ? 409 ASP A CG 1 ATOM 3224 O OD1 . ASP A 1 409 ? 20.972 63.593 3.901 1.00 9.30 ? 409 ASP A OD1 1 ATOM 3225 O OD2 . ASP A 1 409 ? 22.142 63.758 5.735 1.00 9.93 ? 409 ASP A OD2 1 ATOM 3226 N N . ARG A 1 410 ? 18.559 61.498 3.915 1.00 9.53 ? 410 ARG A N 1 ATOM 3227 C CA . ARG A 1 410 ? 17.153 61.602 4.360 1.00 10.62 ? 410 ARG A CA 1 ATOM 3228 C C . ARG A 1 410 ? 16.339 62.241 3.248 1.00 11.92 ? 410 ARG A C 1 ATOM 3229 O O . ARG A 1 410 ? 16.892 62.979 2.398 1.00 12.03 ? 410 ARG A O 1 ATOM 3230 C CB . ARG A 1 410 ? 17.048 62.433 5.646 1.00 11.73 ? 410 ARG A CB 1 ATOM 3231 C CG . ARG A 1 410 ? 17.526 63.870 5.545 1.00 13.06 ? 410 ARG A CG 1 ATOM 3232 C CD . ARG A 1 410 ? 17.472 64.424 6.953 1.00 13.80 ? 410 ARG A CD 1 ATOM 3233 N NE . ARG A 1 410 ? 18.147 65.712 7.087 1.00 15.47 ? 410 ARG A NE 1 ATOM 3234 C CZ . ARG A 1 410 ? 17.590 66.891 6.845 1.00 16.84 ? 410 ARG A CZ 1 ATOM 3235 N NH1 . ARG A 1 410 ? 16.310 66.953 6.431 1.00 17.62 ? 410 ARG A NH1 1 ATOM 3236 N NH2 . ARG A 1 410 ? 18.306 68.002 7.041 1.00 17.16 ? 410 ARG A NH2 1 ATOM 3237 N N . SER A 1 411 ? 15.057 61.857 3.177 1.00 11.16 ? 411 SER A N 1 ATOM 3238 C CA A SER A 1 411 ? 14.094 62.364 2.206 0.50 12.29 ? 411 SER A CA 1 ATOM 3239 C CA B SER A 1 411 ? 14.104 62.619 2.334 0.50 12.28 ? 411 SER A CA 1 ATOM 3240 C C . SER A 1 411 ? 14.629 62.543 0.787 1.00 11.56 ? 411 SER A C 1 ATOM 3241 O O A SER A 1 411 ? 15.093 61.574 0.185 0.50 12.16 ? 411 SER A O 1 ATOM 3242 O O B SER A 1 411 ? 15.107 61.577 0.444 0.50 12.18 ? 411 SER A O 1 ATOM 3243 C CB A SER A 1 411 ? 13.425 63.644 2.763 0.50 13.53 ? 411 SER A CB 1 ATOM 3244 C CB B SER A 1 411 ? 13.814 64.050 2.838 0.50 13.93 ? 411 SER A CB 1 ATOM 3245 O OG A SER A 1 411 ? 14.340 64.697 2.983 0.50 15.51 ? 411 SER A OG 1 ATOM 3246 O OG B SER A 1 411 ? 12.710 64.606 2.160 0.50 15.91 ? 411 SER A OG 1 ATOM 3247 N N . ASP A 1 412 ? 14.562 63.756 0.228 1.00 11.34 ? 412 ASP A N 1 ATOM 3248 C CA . ASP A 1 412 ? 15.065 63.962 -1.138 1.00 10.15 ? 412 ASP A CA 1 ATOM 3249 C C . ASP A 1 412 ? 16.422 64.712 -1.097 1.00 9.63 ? 412 ASP A C 1 ATOM 3250 O O . ASP A 1 412 ? 16.804 65.291 -2.095 1.00 9.52 ? 412 ASP A O 1 ATOM 3251 C CB . ASP A 1 412 ? 14.068 64.813 -1.956 1.00 11.28 ? 412 ASP A CB 1 ATOM 3252 C CG . ASP A 1 412 ? 13.896 66.236 -1.370 1.00 10.46 ? 412 ASP A CG 1 ATOM 3253 O OD1 . ASP A 1 412 ? 14.410 66.527 -0.275 1.00 12.04 ? 412 ASP A OD1 1 ATOM 3254 O OD2 . ASP A 1 412 ? 13.218 67.053 -2.045 1.00 13.75 ? 412 ASP A OD2 1 ATOM 3255 N N . ASN A 1 413 ? 17.104 64.639 0.042 1.00 9.67 ? 413 ASN A N 1 ATOM 3256 C CA . ASN A 1 413 ? 18.382 65.362 0.192 1.00 9.35 ? 413 ASN A CA 1 ATOM 3257 C C . ASN A 1 413 ? 19.549 64.498 -0.365 1.00 8.51 ? 413 ASN A C 1 ATOM 3258 O O . ASN A 1 413 ? 20.239 63.804 0.397 1.00 9.20 ? 413 ASN A O 1 ATOM 3259 C CB . ASN A 1 413 ? 18.665 65.703 1.658 1.00 10.14 ? 413 ASN A CB 1 ATOM 3260 C CG . ASN A 1 413 ? 17.727 66.799 2.275 1.00 9.37 ? 413 ASN A CG 1 ATOM 3261 O OD1 . ASN A 1 413 ? 18.025 67.300 3.360 1.00 11.60 ? 413 ASN A OD1 1 ATOM 3262 N ND2 . ASN A 1 413 ? 16.620 67.163 1.599 1.00 10.81 ? 413 ASN A ND2 1 ATOM 3263 N N . TYR A 1 414 ? 19.724 64.574 -1.688 1.00 7.80 ? 414 TYR A N 1 ATOM 3264 C CA . TYR A 1 414 ? 20.782 63.858 -2.401 1.00 8.47 ? 414 TYR A CA 1 ATOM 3265 C C . TYR A 1 414 ? 22.016 64.757 -2.478 1.00 8.48 ? 414 TYR A C 1 ATOM 3266 O O . TYR A 1 414 ? 21.924 65.965 -2.780 1.00 9.03 ? 414 TYR A O 1 ATOM 3267 C CB . TYR A 1 414 ? 20.306 63.492 -3.818 1.00 9.41 ? 414 TYR A CB 1 ATOM 3268 C CG . TYR A 1 414 ? 19.308 62.371 -3.857 1.00 8.37 ? 414 TYR A CG 1 ATOM 3269 C CD1 . TYR A 1 414 ? 17.966 62.617 -3.621 1.00 10.18 ? 414 TYR A CD1 1 ATOM 3270 C CD2 . TYR A 1 414 ? 19.736 61.064 -4.050 1.00 9.37 ? 414 TYR A CD2 1 ATOM 3271 C CE1 . TYR A 1 414 ? 17.051 61.530 -3.578 1.00 10.55 ? 414 TYR A CE1 1 ATOM 3272 C CE2 . TYR A 1 414 ? 18.823 59.968 -4.020 1.00 9.20 ? 414 TYR A CE2 1 ATOM 3273 C CZ . TYR A 1 414 ? 17.511 60.246 -3.789 1.00 9.52 ? 414 TYR A CZ 1 ATOM 3274 O OH . TYR A 1 414 ? 16.607 59.177 -3.804 1.00 10.14 ? 414 TYR A OH 1 ATOM 3275 N N . TRP A 1 415 ? 23.162 64.121 -2.173 1.00 8.28 ? 415 TRP A N 1 ATOM 3276 C CA . TRP A 1 415 ? 24.436 64.830 -2.082 1.00 7.93 ? 415 TRP A CA 1 ATOM 3277 C C . TRP A 1 415 ? 25.141 64.895 -3.407 1.00 8.52 ? 415 TRP A C 1 ATOM 3278 O O . TRP A 1 415 ? 26.275 64.409 -3.530 1.00 9.57 ? 415 TRP A O 1 ATOM 3279 C CB . TRP A 1 415 ? 25.312 64.146 -1.040 1.00 7.60 ? 415 TRP A CB 1 ATOM 3280 C CG . TRP A 1 415 ? 24.756 64.229 0.397 1.00 7.61 ? 415 TRP A CG 1 ATOM 3281 C CD1 . TRP A 1 415 ? 23.443 63.951 0.813 1.00 8.75 ? 415 TRP A CD1 1 ATOM 3282 C CD2 . TRP A 1 415 ? 25.492 64.505 1.588 1.00 7.97 ? 415 TRP A CD2 1 ATOM 3283 N NE1 . TRP A 1 415 ? 23.362 64.044 2.181 1.00 9.17 ? 415 TRP A NE1 1 ATOM 3284 C CE2 . TRP A 1 415 ? 24.603 64.376 2.691 1.00 8.00 ? 415 TRP A CE2 1 ATOM 3285 C CE3 . TRP A 1 415 ? 26.847 64.847 1.838 1.00 8.12 ? 415 TRP A CE3 1 ATOM 3286 C CZ2 . TRP A 1 415 ? 25.017 64.569 4.006 1.00 8.74 ? 415 TRP A CZ2 1 ATOM 3287 C CZ3 . TRP A 1 415 ? 27.257 65.030 3.082 1.00 8.32 ? 415 TRP A CZ3 1 ATOM 3288 C CH2 . TRP A 1 415 ? 26.367 64.894 4.207 1.00 8.36 ? 415 TRP A CH2 1 ATOM 3289 N N . SER A 1 416 ? 24.485 65.466 -4.407 1.00 7.34 ? 416 SER A N 1 ATOM 3290 C CA . SER A 1 416 ? 25.153 65.602 -5.713 1.00 7.88 ? 416 SER A CA 1 ATOM 3291 C C . SER A 1 416 ? 25.707 67.008 -5.940 1.00 7.13 ? 416 SER A C 1 ATOM 3292 O O . SER A 1 416 ? 26.349 67.240 -6.939 1.00 7.99 ? 416 SER A O 1 ATOM 3293 C CB . SER A 1 416 ? 24.206 65.165 -6.831 1.00 7.24 ? 416 SER A CB 1 ATOM 3294 O OG . SER A 1 416 ? 22.879 65.753 -6.677 1.00 8.56 ? 416 SER A OG 1 ATOM 3295 N N . GLY A 1 417 ? 25.480 67.938 -5.013 1.00 6.93 ? 417 GLY A N 1 ATOM 3296 C CA . GLY A 1 417 ? 26.044 69.269 -5.193 1.00 7.67 ? 417 GLY A CA 1 ATOM 3297 C C . GLY A 1 417 ? 27.565 69.269 -5.109 1.00 6.71 ? 417 GLY A C 1 ATOM 3298 O O . GLY A 1 417 ? 28.233 69.977 -5.869 1.00 7.35 ? 417 GLY A O 1 ATOM 3299 N N . TYR A 1 418 ? 28.134 68.454 -4.213 1.00 6.56 ? 418 TYR A N 1 ATOM 3300 C CA . TYR A 1 418 ? 29.608 68.477 -4.032 1.00 6.61 ? 418 TYR A CA 1 ATOM 3301 C C . TYR A 1 418 ? 30.347 67.860 -5.212 1.00 6.19 ? 418 TYR A C 1 ATOM 3302 O O . TYR A 1 418 ? 31.601 67.860 -5.257 1.00 6.86 ? 418 TYR A O 1 ATOM 3303 C CB . TYR A 1 418 ? 30.012 67.818 -2.704 1.00 6.38 ? 418 TYR A CB 1 ATOM 3304 C CG . TYR A 1 418 ? 30.109 66.304 -2.750 1.00 6.79 ? 418 TYR A CG 1 ATOM 3305 C CD1 . TYR A 1 418 ? 28.970 65.469 -2.565 1.00 7.72 ? 418 TYR A CD1 1 ATOM 3306 C CD2 . TYR A 1 418 ? 31.338 65.704 -2.953 1.00 6.88 ? 418 TYR A CD2 1 ATOM 3307 C CE1 . TYR A 1 418 ? 29.073 64.049 -2.581 1.00 6.35 ? 418 TYR A CE1 1 ATOM 3308 C CE2 . TYR A 1 418 ? 31.461 64.328 -2.987 1.00 6.38 ? 418 TYR A CE2 1 ATOM 3309 C CZ . TYR A 1 418 ? 30.340 63.505 -2.790 1.00 6.17 ? 418 TYR A CZ 1 ATOM 3310 O OH . TYR A 1 418 ? 30.532 62.134 -2.787 1.00 7.10 ? 418 TYR A OH 1 ATOM 3311 N N . TYR A 1 419 ? 29.623 67.277 -6.169 1.00 6.23 ? 419 TYR A N 1 ATOM 3312 C CA . TYR A 1 419 ? 30.279 66.834 -7.401 1.00 5.90 ? 419 TYR A CA 1 ATOM 3313 C C . TYR A 1 419 ? 30.785 68.055 -8.207 1.00 6.53 ? 419 TYR A C 1 ATOM 3314 O O . TYR A 1 419 ? 31.621 67.851 -9.102 1.00 6.90 ? 419 TYR A O 1 ATOM 3315 C CB . TYR A 1 419 ? 29.341 66.030 -8.292 1.00 6.57 ? 419 TYR A CB 1 ATOM 3316 C CG . TYR A 1 419 ? 28.709 64.826 -7.640 1.00 5.76 ? 419 TYR A CG 1 ATOM 3317 C CD1 . TYR A 1 419 ? 29.274 64.158 -6.545 1.00 6.61 ? 419 TYR A CD1 1 ATOM 3318 C CD2 . TYR A 1 419 ? 27.530 64.316 -8.211 1.00 7.05 ? 419 TYR A CD2 1 ATOM 3319 C CE1 . TYR A 1 419 ? 28.691 63.011 -6.018 1.00 6.61 ? 419 TYR A CE1 1 ATOM 3320 C CE2 . TYR A 1 419 ? 26.932 63.167 -7.694 1.00 7.07 ? 419 TYR A CE2 1 ATOM 3321 C CZ . TYR A 1 419 ? 27.518 62.524 -6.601 1.00 6.46 ? 419 TYR A CZ 1 ATOM 3322 O OH . TYR A 1 419 ? 26.929 61.382 -6.084 1.00 7.25 ? 419 TYR A OH 1 ATOM 3323 N N . THR A 1 420 ? 30.310 69.267 -7.863 1.00 6.51 ? 420 THR A N 1 ATOM 3324 C CA . THR A 1 420 ? 30.697 70.474 -8.586 1.00 7.13 ? 420 THR A CA 1 ATOM 3325 C C . THR A 1 420 ? 31.234 71.582 -7.711 1.00 6.80 ? 420 THR A C 1 ATOM 3326 O O . THR A 1 420 ? 32.008 72.429 -8.177 1.00 7.50 ? 420 THR A O 1 ATOM 3327 C CB . THR A 1 420 ? 29.446 70.982 -9.369 1.00 7.22 ? 420 THR A CB 1 ATOM 3328 O OG1 . THR A 1 420 ? 28.998 69.950 -10.250 1.00 8.12 ? 420 THR A OG1 1 ATOM 3329 C CG2 . THR A 1 420 ? 29.717 72.234 -10.225 1.00 8.10 ? 420 THR A CG2 1 ATOM 3330 N N . SER A 1 421 ? 30.890 71.606 -6.433 1.00 6.58 ? 421 SER A N 1 ATOM 3331 C CA . SER A 1 421 ? 31.277 72.736 -5.565 1.00 7.36 ? 421 SER A CA 1 ATOM 3332 C C . SER A 1 421 ? 32.743 73.069 -5.627 1.00 7.10 ? 421 SER A C 1 ATOM 3333 O O . SER A 1 421 ? 33.601 72.171 -5.569 1.00 6.93 ? 421 SER A O 1 ATOM 3334 C CB . SER A 1 421 ? 30.913 72.429 -4.098 1.00 7.00 ? 421 SER A CB 1 ATOM 3335 O OG . SER A 1 421 ? 29.509 72.223 -4.033 1.00 7.73 ? 421 SER A OG 1 ATOM 3336 N N . ARG A 1 422 ? 33.032 74.379 -5.663 1.00 6.25 ? 422 ARG A N 1 ATOM 3337 C CA . ARG A 1 422 ? 34.443 74.864 -5.739 1.00 7.33 ? 422 ARG A CA 1 ATOM 3338 C C . ARG A 1 422 ? 35.176 74.198 -6.910 1.00 6.85 ? 422 ARG A C 1 ATOM 3339 O O . ARG A 1 422 ? 36.217 73.514 -6.774 1.00 7.33 ? 422 ARG A O 1 ATOM 3340 C CB . ARG A 1 422 ? 35.201 74.639 -4.428 1.00 8.15 ? 422 ARG A CB 1 ATOM 3341 C CG . ARG A 1 422 ? 34.943 75.724 -3.353 1.00 8.43 ? 422 ARG A CG 1 ATOM 3342 C CD . ARG A 1 422 ? 33.494 75.832 -2.864 1.00 8.33 ? 422 ARG A CD 1 ATOM 3343 N NE . ARG A 1 422 ? 33.452 76.831 -1.772 1.00 8.58 ? 422 ARG A NE 1 ATOM 3344 C CZ . ARG A 1 422 ? 33.492 76.530 -0.482 1.00 8.72 ? 422 ARG A CZ 1 ATOM 3345 N NH1 . ARG A 1 422 ? 33.505 75.279 -0.059 1.00 8.48 ? 422 ARG A NH1 1 ATOM 3346 N NH2 . ARG A 1 422 ? 33.746 77.514 0.414 1.00 9.17 ? 422 ARG A NH2 1 ATOM 3347 N N . PRO A 1 423 ? 34.682 74.420 -8.109 1.00 6.73 ? 423 PRO A N 1 ATOM 3348 C CA . PRO A 1 423 ? 35.292 73.809 -9.285 1.00 6.71 ? 423 PRO A CA 1 ATOM 3349 C C . PRO A 1 423 ? 36.678 74.285 -9.619 1.00 5.87 ? 423 PRO A C 1 ATOM 3350 O O . PRO A 1 423 ? 37.402 73.555 -10.312 1.00 7.23 ? 423 PRO A O 1 ATOM 3351 C CB . PRO A 1 423 ? 34.249 74.071 -10.409 1.00 6.58 ? 423 PRO A CB 1 ATOM 3352 C CG . PRO A 1 423 ? 33.675 75.434 -9.990 1.00 7.06 ? 423 PRO A CG 1 ATOM 3353 C CD . PRO A 1 423 ? 33.551 75.304 -8.468 1.00 7.12 ? 423 PRO A CD 1 ATOM 3354 N N . TYR A 1 424 ? 37.072 75.474 -9.173 1.00 7.08 ? 424 TYR A N 1 ATOM 3355 C CA . TYR A 1 424 ? 38.448 75.907 -9.446 1.00 7.16 ? 424 TYR A CA 1 ATOM 3356 C C . TYR A 1 424 ? 39.422 74.895 -8.860 1.00 6.99 ? 424 TYR A C 1 ATOM 3357 O O . TYR A 1 424 ? 40.412 74.485 -9.522 1.00 6.75 ? 424 TYR A O 1 ATOM 3358 C CB . TYR A 1 424 ? 38.669 77.299 -8.797 1.00 7.85 ? 424 TYR A CB 1 ATOM 3359 C CG . TYR A 1 424 ? 40.049 77.841 -9.050 1.00 7.54 ? 424 TYR A CG 1 ATOM 3360 C CD1 . TYR A 1 424 ? 41.121 77.554 -8.185 1.00 8.16 ? 424 TYR A CD1 1 ATOM 3361 C CD2 . TYR A 1 424 ? 40.278 78.633 -10.162 1.00 9.83 ? 424 TYR A CD2 1 ATOM 3362 C CE1 . TYR A 1 424 ? 42.405 78.069 -8.474 1.00 10.18 ? 424 TYR A CE1 1 ATOM 3363 C CE2 . TYR A 1 424 ? 41.505 79.145 -10.427 1.00 11.11 ? 424 TYR A CE2 1 ATOM 3364 C CZ . TYR A 1 424 ? 42.563 78.869 -9.591 1.00 10.28 ? 424 TYR A CZ 1 ATOM 3365 O OH . TYR A 1 424 ? 43.784 79.473 -9.934 1.00 14.31 ? 424 TYR A OH 1 ATOM 3366 N N . HIS A 1 425 ? 39.134 74.478 -7.619 1.00 6.74 ? 425 HIS A N 1 ATOM 3367 C CA . HIS A 1 425 ? 40.080 73.569 -6.945 1.00 5.92 ? 425 HIS A CA 1 ATOM 3368 C C . HIS A 1 425 ? 39.964 72.153 -7.432 1.00 6.65 ? 425 HIS A C 1 ATOM 3369 O O . HIS A 1 425 ? 40.936 71.365 -7.379 1.00 6.34 ? 425 HIS A O 1 ATOM 3370 C CB . HIS A 1 425 ? 39.919 73.708 -5.415 1.00 7.46 ? 425 HIS A CB 1 ATOM 3371 C CG . HIS A 1 425 ? 39.875 75.134 -4.995 1.00 8.07 ? 425 HIS A CG 1 ATOM 3372 N ND1 . HIS A 1 425 ? 40.997 75.901 -4.716 1.00 10.89 ? 425 HIS A ND1 1 ATOM 3373 C CD2 . HIS A 1 425 ? 38.820 75.970 -4.996 1.00 6.94 ? 425 HIS A CD2 1 ATOM 3374 C CE1 . HIS A 1 425 ? 40.606 77.165 -4.556 1.00 6.86 ? 425 HIS A CE1 1 ATOM 3375 N NE2 . HIS A 1 425 ? 39.297 77.223 -4.723 1.00 11.67 ? 425 HIS A NE2 1 ATOM 3376 N N . LYS A 1 426 ? 38.768 71.759 -7.904 1.00 6.27 ? 426 LYS A N 1 ATOM 3377 C CA . LYS A 1 426 ? 38.617 70.447 -8.557 1.00 6.45 ? 426 LYS A CA 1 ATOM 3378 C C . LYS A 1 426 ? 39.495 70.395 -9.819 1.00 6.10 ? 426 LYS A C 1 ATOM 3379 O O . LYS A 1 426 ? 40.156 69.371 -10.088 1.00 6.49 ? 426 LYS A O 1 ATOM 3380 C CB . LYS A 1 426 ? 37.113 70.226 -8.949 1.00 6.94 ? 426 LYS A CB 1 ATOM 3381 C CG . LYS A 1 426 ? 36.248 69.880 -7.737 1.00 6.46 ? 426 LYS A CG 1 ATOM 3382 C CD . LYS A 1 426 ? 34.749 69.937 -8.119 1.00 6.84 ? 426 LYS A CD 1 ATOM 3383 C CE . LYS A 1 426 ? 33.890 69.054 -7.208 1.00 6.77 ? 426 LYS A CE 1 ATOM 3384 N NZ . LYS A 1 426 ? 33.853 69.430 -5.770 1.00 7.03 ? 426 LYS A NZ 1 ATOM 3385 N N . ARG A 1 427 ? 39.564 71.496 -10.589 1.00 5.81 ? 427 ARG A N 1 ATOM 3386 C CA . ARG A 1 427 ? 40.409 71.478 -11.751 1.00 6.62 ? 427 ARG A CA 1 ATOM 3387 C C . ARG A 1 427 ? 41.879 71.504 -11.293 1.00 6.61 ? 427 ARG A C 1 ATOM 3388 O O . ARG A 1 427 ? 42.725 70.810 -11.874 1.00 6.45 ? 427 ARG A O 1 ATOM 3389 C CB . ARG A 1 427 ? 40.075 72.713 -12.608 1.00 7.50 ? 427 ARG A CB 1 ATOM 3390 C CG . ARG A 1 427 ? 41.009 72.963 -13.783 1.00 8.79 ? 427 ARG A CG 1 ATOM 3391 C CD . ARG A 1 427 ? 41.075 71.850 -14.806 1.00 9.69 ? 427 ARG A CD 1 ATOM 3392 N NE . ARG A 1 427 ? 42.131 72.244 -15.754 1.00 10.39 ? 427 ARG A NE 1 ATOM 3393 C CZ . ARG A 1 427 ? 42.943 71.416 -16.347 1.00 10.19 ? 427 ARG A CZ 1 ATOM 3394 N NH1 . ARG A 1 427 ? 42.885 70.115 -16.162 1.00 10.25 ? 427 ARG A NH1 1 ATOM 3395 N NH2 . ARG A 1 427 ? 43.926 71.943 -17.127 1.00 10.94 ? 427 ARG A NH2 1 ATOM 3396 N N . MET A 1 428 ? 42.197 72.312 -10.261 1.00 6.58 ? 428 MET A N 1 ATOM 3397 C CA . MET A 1 428 ? 43.581 72.359 -9.764 1.00 6.64 ? 428 MET A CA 1 ATOM 3398 C C . MET A 1 428 ? 44.066 70.965 -9.350 1.00 6.64 ? 428 MET A C 1 ATOM 3399 O O . MET A 1 428 ? 45.263 70.624 -9.554 1.00 6.73 ? 428 MET A O 1 ATOM 3400 C CB . MET A 1 428 ? 43.651 73.309 -8.571 1.00 7.69 ? 428 MET A CB 1 ATOM 3401 C CG . MET A 1 428 ? 45.113 73.715 -8.248 1.00 7.28 ? 428 MET A CG 1 ATOM 3402 S SD . MET A 1 428 ? 44.999 75.010 -6.970 1.00 9.70 ? 428 MET A SD 1 ATOM 3403 C CE . MET A 1 428 ? 46.726 75.545 -6.936 1.00 9.77 ? 428 MET A CE 1 ATOM 3404 N N . ASP A 1 429 ? 43.190 70.151 -8.751 1.00 5.99 ? 429 ASP A N 1 ATOM 3405 C CA . ASP A 1 429 ? 43.555 68.808 -8.354 1.00 5.86 ? 429 ASP A CA 1 ATOM 3406 C C . ASP A 1 429 ? 44.108 67.997 -9.514 1.00 5.91 ? 429 ASP A C 1 ATOM 3407 O O . ASP A 1 429 ? 45.093 67.274 -9.371 1.00 6.25 ? 429 ASP A O 1 ATOM 3408 C CB . ASP A 1 429 ? 42.286 68.098 -7.835 1.00 7.11 ? 429 ASP A CB 1 ATOM 3409 C CG . ASP A 1 429 ? 42.562 66.624 -7.518 1.00 6.14 ? 429 ASP A CG 1 ATOM 3410 O OD1 . ASP A 1 429 ? 43.076 66.379 -6.411 1.00 7.73 ? 429 ASP A OD1 1 ATOM 3411 O OD2 . ASP A 1 429 ? 42.252 65.729 -8.377 1.00 6.68 ? 429 ASP A OD2 1 ATOM 3412 N N . ARG A 1 430 ? 43.463 68.113 -10.689 1.00 6.20 ? 430 ARG A N 1 ATOM 3413 C CA . ARG A 1 430 ? 43.913 67.337 -11.824 1.00 5.45 ? 430 ARG A CA 1 ATOM 3414 C C . ARG A 1 430 ? 45.215 67.856 -12.398 1.00 5.88 ? 430 ARG A C 1 ATOM 3415 O O . ARG A 1 430 ? 46.068 67.052 -12.865 1.00 6.43 ? 430 ARG A O 1 ATOM 3416 C CB . ARG A 1 430 ? 42.823 67.390 -12.906 1.00 6.47 ? 430 ARG A CB 1 ATOM 3417 C CG . ARG A 1 430 ? 41.533 66.615 -12.506 1.00 6.88 ? 430 ARG A CG 1 ATOM 3418 C CD . ARG A 1 430 ? 41.808 65.167 -12.077 1.00 6.45 ? 430 ARG A CD 1 ATOM 3419 N NE . ARG A 1 430 ? 40.559 64.407 -12.094 1.00 6.12 ? 430 ARG A NE 1 ATOM 3420 C CZ . ARG A 1 430 ? 39.880 64.070 -11.015 1.00 6.29 ? 430 ARG A CZ 1 ATOM 3421 N NH1 . ARG A 1 430 ? 40.278 64.402 -9.777 1.00 6.74 ? 430 ARG A NH1 1 ATOM 3422 N NH2 . ARG A 1 430 ? 38.744 63.355 -11.150 1.00 6.86 ? 430 ARG A NH2 1 ATOM 3423 N N . VAL A 1 431 ? 45.410 69.174 -12.334 1.00 5.75 ? 431 VAL A N 1 ATOM 3424 C CA . VAL A 1 431 ? 46.666 69.734 -12.818 1.00 6.86 ? 431 VAL A CA 1 ATOM 3425 C C . VAL A 1 431 ? 47.804 69.250 -11.901 1.00 6.61 ? 431 VAL A C 1 ATOM 3426 O O . VAL A 1 431 ? 48.851 68.766 -12.368 1.00 7.16 ? 431 VAL A O 1 ATOM 3427 C CB . VAL A 1 431 ? 46.545 71.247 -12.794 1.00 6.32 ? 431 VAL A CB 1 ATOM 3428 C CG1 . VAL A 1 431 ? 47.932 71.865 -13.149 1.00 8.43 ? 431 VAL A CG1 1 ATOM 3429 C CG2 . VAL A 1 431 ? 45.510 71.702 -13.841 1.00 8.18 ? 431 VAL A CG2 1 ATOM 3430 N N . LEU A 1 432 ? 47.621 69.366 -10.585 1.00 5.99 ? 432 LEU A N 1 ATOM 3431 C CA . LEU A 1 432 ? 48.660 68.918 -9.651 1.00 6.36 ? 432 LEU A CA 1 ATOM 3432 C C . LEU A 1 432 ? 48.852 67.414 -9.754 1.00 5.92 ? 432 LEU A C 1 ATOM 3433 O O . LEU A 1 432 ? 49.984 66.940 -9.606 1.00 6.83 ? 432 LEU A O 1 ATOM 3434 C CB . LEU A 1 432 ? 48.335 69.380 -8.230 1.00 7.26 ? 432 LEU A CB 1 ATOM 3435 C CG . LEU A 1 432 ? 49.352 69.016 -7.158 1.00 7.24 ? 432 LEU A CG 1 ATOM 3436 C CD1 . LEU A 1 432 ? 50.807 69.524 -7.495 1.00 7.37 ? 432 LEU A CD1 1 ATOM 3437 C CD2 . LEU A 1 432 ? 48.868 69.637 -5.840 1.00 8.13 ? 432 LEU A CD2 1 ATOM 3438 N N . MET A 1 433 ? 47.780 66.628 -9.993 1.00 5.66 ? 433 MET A N 1 ATOM 3439 C CA . MET A 1 433 ? 47.936 65.179 -10.175 1.00 6.43 ? 433 MET A CA 1 ATOM 3440 C C . MET A 1 433 ? 49.000 64.884 -11.209 1.00 5.70 ? 433 MET A C 1 ATOM 3441 O O . MET A 1 433 ? 49.890 64.031 -11.002 1.00 6.03 ? 433 MET A O 1 ATOM 3442 C CB . MET A 1 433 ? 46.602 64.592 -10.640 1.00 6.77 ? 433 MET A CB 1 ATOM 3443 C CG . MET A 1 433 ? 46.714 63.114 -10.934 1.00 6.85 ? 433 MET A CG 1 ATOM 3444 S SD . MET A 1 433 ? 45.152 62.435 -11.589 1.00 8.02 ? 433 MET A SD 1 ATOM 3445 C CE . MET A 1 433 ? 45.142 63.114 -13.209 1.00 9.56 ? 433 MET A CE 1 ATOM 3446 N N . HIS A 1 434 ? 48.892 65.571 -12.326 1.00 5.91 ? 434 HIS A N 1 ATOM 3447 C CA . HIS A 1 434 ? 49.819 65.372 -13.430 1.00 5.67 ? 434 HIS A CA 1 ATOM 3448 C C . HIS A 1 434 ? 51.229 65.884 -13.134 1.00 5.69 ? 434 HIS A C 1 ATOM 3449 O O . HIS A 1 434 ? 52.225 65.224 -13.497 1.00 6.22 ? 434 HIS A O 1 ATOM 3450 C CB . HIS A 1 434 ? 49.268 66.050 -14.694 1.00 6.73 ? 434 HIS A CB 1 ATOM 3451 C CG . HIS A 1 434 ? 50.255 65.999 -15.826 1.00 6.12 ? 434 HIS A CG 1 ATOM 3452 N ND1 . HIS A 1 434 ? 51.056 67.073 -16.196 1.00 9.16 ? 434 HIS A ND1 1 ATOM 3453 C CD2 . HIS A 1 434 ? 50.688 64.925 -16.532 1.00 5.12 ? 434 HIS A CD2 1 ATOM 3454 C CE1 . HIS A 1 434 ? 51.942 66.640 -17.109 1.00 5.46 ? 434 HIS A CE1 1 ATOM 3455 N NE2 . HIS A 1 434 ? 51.738 65.354 -17.308 1.00 9.51 ? 434 HIS A NE2 1 ATOM 3456 N N . TYR A 1 435 ? 51.325 67.042 -12.496 1.00 6.35 ? 435 TYR A N 1 ATOM 3457 C CA . TYR A 1 435 ? 52.631 67.605 -12.160 1.00 7.02 ? 435 TYR A CA 1 ATOM 3458 C C . TYR A 1 435 ? 53.367 66.691 -11.184 1.00 6.92 ? 435 TYR A C 1 ATOM 3459 O O . TYR A 1 435 ? 54.580 66.502 -11.314 1.00 6.84 ? 435 TYR A O 1 ATOM 3460 C CB A TYR A 1 435 ? 52.470 69.021 -11.531 0.50 7.92 ? 435 TYR A CB 1 ATOM 3461 C CB B TYR A 1 435 ? 52.534 69.084 -11.820 0.50 7.71 ? 435 TYR A CB 1 ATOM 3462 C CG A TYR A 1 435 ? 52.399 70.166 -12.526 0.50 9.65 ? 435 TYR A CG 1 ATOM 3463 C CG B TYR A 1 435 ? 52.433 69.948 -13.065 0.50 8.36 ? 435 TYR A CG 1 ATOM 3464 C CD1 A TYR A 1 435 ? 51.445 70.191 -13.545 0.50 9.25 ? 435 TYR A CD1 1 ATOM 3465 C CD1 B TYR A 1 435 ? 53.498 70.036 -13.953 0.50 12.26 ? 435 TYR A CD1 1 ATOM 3466 C CD2 A TYR A 1 435 ? 53.240 71.263 -12.400 0.50 11.16 ? 435 TYR A CD2 1 ATOM 3467 C CD2 B TYR A 1 435 ? 51.294 70.684 -13.350 0.50 8.89 ? 435 TYR A CD2 1 ATOM 3468 C CE1 A TYR A 1 435 ? 51.321 71.284 -14.415 0.50 10.71 ? 435 TYR A CE1 1 ATOM 3469 C CE1 B TYR A 1 435 ? 53.432 70.854 -15.078 0.50 13.90 ? 435 TYR A CE1 1 ATOM 3470 C CE2 A TYR A 1 435 ? 53.134 72.354 -13.259 0.50 14.02 ? 435 TYR A CE2 1 ATOM 3471 C CE2 B TYR A 1 435 ? 51.207 71.490 -14.482 0.50 9.60 ? 435 TYR A CE2 1 ATOM 3472 C CZ A TYR A 1 435 ? 52.176 72.361 -14.259 0.50 11.94 ? 435 TYR A CZ 1 ATOM 3473 C CZ B TYR A 1 435 ? 52.283 71.578 -15.338 0.50 10.93 ? 435 TYR A CZ 1 ATOM 3474 O OH A TYR A 1 435 ? 52.076 73.441 -15.102 0.50 15.47 ? 435 TYR A OH 1 ATOM 3475 O OH B TYR A 1 435 ? 52.229 72.401 -16.469 0.50 12.89 ? 435 TYR A OH 1 ATOM 3476 N N . VAL A 1 436 ? 52.658 66.105 -10.232 1.00 6.46 ? 436 VAL A N 1 ATOM 3477 C CA . VAL A 1 436 ? 53.328 65.215 -9.293 1.00 6.48 ? 436 VAL A CA 1 ATOM 3478 C C . VAL A 1 436 ? 53.850 64.004 -10.087 1.00 7.09 ? 436 VAL A C 1 ATOM 3479 O O . VAL A 1 436 ? 55.005 63.564 -9.907 1.00 6.69 ? 436 VAL A O 1 ATOM 3480 C CB . VAL A 1 436 ? 52.350 64.760 -8.194 1.00 6.40 ? 436 VAL A CB 1 ATOM 3481 C CG1 . VAL A 1 436 ? 52.894 63.525 -7.377 1.00 7.96 ? 436 VAL A CG1 1 ATOM 3482 C CG2 . VAL A 1 436 ? 52.194 65.961 -7.169 1.00 6.75 ? 436 VAL A CG2 1 ATOM 3483 N N . ARG A 1 437 ? 53.025 63.399 -10.948 1.00 6.27 ? 437 ARG A N 1 ATOM 3484 C CA . ARG A 1 437 ? 53.498 62.241 -11.735 1.00 6.88 ? 437 ARG A CA 1 ATOM 3485 C C . ARG A 1 437 ? 54.730 62.640 -12.545 1.00 6.79 ? 437 ARG A C 1 ATOM 3486 O O . ARG A 1 437 ? 55.731 61.893 -12.565 1.00 6.72 ? 437 ARG A O 1 ATOM 3487 C CB . ARG A 1 437 ? 52.394 61.751 -12.679 1.00 6.60 ? 437 ARG A CB 1 ATOM 3488 C CG . ARG A 1 437 ? 52.920 60.771 -13.715 1.00 7.54 ? 437 ARG A CG 1 ATOM 3489 C CD . ARG A 1 437 ? 51.764 60.275 -14.573 1.00 8.27 ? 437 ARG A CD 1 ATOM 3490 N NE . ARG A 1 437 ? 52.295 59.592 -15.755 1.00 7.79 ? 437 ARG A NE 1 ATOM 3491 C CZ . ARG A 1 437 ? 51.565 58.757 -16.494 1.00 7.22 ? 437 ARG A CZ 1 ATOM 3492 N NH1 . ARG A 1 437 ? 50.284 58.457 -16.175 1.00 8.07 ? 437 ARG A NH1 1 ATOM 3493 N NH2 . ARG A 1 437 ? 52.094 58.228 -17.577 1.00 8.21 ? 437 ARG A NH2 1 ATOM 3494 N N . ALA A 1 438 ? 54.634 63.782 -13.246 1.00 6.24 ? 438 ALA A N 1 ATOM 3495 C CA . ALA A 1 438 ? 55.772 64.172 -14.097 1.00 6.87 ? 438 ALA A CA 1 ATOM 3496 C C . ALA A 1 438 ? 57.037 64.483 -13.305 1.00 6.91 ? 438 ALA A C 1 ATOM 3497 O O . ALA A 1 438 ? 58.130 64.118 -13.780 1.00 7.06 ? 438 ALA A O 1 ATOM 3498 C CB . ALA A 1 438 ? 55.382 65.341 -14.992 1.00 7.71 ? 438 ALA A CB 1 ATOM 3499 N N . ALA A 1 439 ? 56.909 65.122 -12.139 1.00 7.50 ? 439 ALA A N 1 ATOM 3500 C CA . ALA A 1 439 ? 58.103 65.409 -11.325 1.00 7.03 ? 439 ALA A CA 1 ATOM 3501 C C . ALA A 1 439 ? 58.704 64.130 -10.786 1.00 7.29 ? 439 ALA A C 1 ATOM 3502 O O . ALA A 1 439 ? 59.954 63.981 -10.787 1.00 7.65 ? 439 ALA A O 1 ATOM 3503 C CB . ALA A 1 439 ? 57.704 66.369 -10.202 1.00 7.29 ? 439 ALA A CB 1 ATOM 3504 N N . GLU A 1 440 ? 57.876 63.202 -10.321 1.00 6.53 ? 440 GLU A N 1 ATOM 3505 C CA . GLU A 1 440 ? 58.438 61.957 -9.793 1.00 6.94 ? 440 GLU A CA 1 ATOM 3506 C C . GLU A 1 440 ? 59.069 61.150 -10.909 1.00 6.83 ? 440 GLU A C 1 ATOM 3507 O O . GLU A 1 440 ? 60.147 60.585 -10.703 1.00 7.72 ? 440 GLU A O 1 ATOM 3508 C CB . GLU A 1 440 ? 57.387 61.101 -9.078 1.00 7.31 ? 440 GLU A CB 1 ATOM 3509 C CG . GLU A 1 440 ? 56.789 61.777 -7.818 1.00 8.26 ? 440 GLU A CG 1 ATOM 3510 C CD . GLU A 1 440 ? 56.137 60.789 -6.904 1.00 10.03 ? 440 GLU A CD 1 ATOM 3511 O OE1 . GLU A 1 440 ? 55.033 60.287 -7.186 1.00 9.70 ? 440 GLU A OE1 1 ATOM 3512 O OE2 . GLU A 1 440 ? 56.766 60.431 -5.888 1.00 10.39 ? 440 GLU A OE2 1 ATOM 3513 N N . MET A 1 441 ? 58.468 61.127 -12.093 1.00 6.40 ? 441 MET A N 1 ATOM 3514 C CA . MET A 1 441 ? 59.046 60.358 -13.196 1.00 6.51 ? 441 MET A CA 1 ATOM 3515 C C . MET A 1 441 ? 60.342 61.020 -13.734 1.00 7.38 ? 441 MET A C 1 ATOM 3516 O O . MET A 1 441 ? 61.363 60.325 -13.845 1.00 7.66 ? 441 MET A O 1 ATOM 3517 C CB . MET A 1 441 ? 58.008 60.265 -14.321 1.00 6.78 ? 441 MET A CB 1 ATOM 3518 C CG . MET A 1 441 ? 58.530 59.489 -15.525 1.00 6.58 ? 441 MET A CG 1 ATOM 3519 S SD . MET A 1 441 ? 57.247 59.257 -16.813 1.00 8.12 ? 441 MET A SD 1 ATOM 3520 C CE . MET A 1 441 ? 56.149 58.086 -15.991 1.00 9.66 ? 441 MET A CE 1 ATOM 3521 N N . LEU A 1 442 ? 60.316 62.304 -14.020 1.00 7.23 ? 442 LEU A N 1 ATOM 3522 C CA . LEU A 1 442 ? 61.527 62.963 -14.557 1.00 7.64 ? 442 LEU A CA 1 ATOM 3523 C C . LEU A 1 442 ? 62.718 62.860 -13.633 1.00 8.05 ? 442 LEU A C 1 ATOM 3524 O O . LEU A 1 442 ? 63.852 62.675 -14.112 1.00 8.40 ? 442 LEU A O 1 ATOM 3525 C CB . LEU A 1 442 ? 61.264 64.458 -14.850 1.00 7.28 ? 442 LEU A CB 1 ATOM 3526 C CG . LEU A 1 442 ? 60.600 64.668 -16.208 1.00 6.85 ? 442 LEU A CG 1 ATOM 3527 C CD1 . LEU A 1 442 ? 60.001 66.043 -16.281 1.00 8.69 ? 442 LEU A CD1 1 ATOM 3528 C CD2 . LEU A 1 442 ? 61.677 64.512 -17.292 1.00 8.89 ? 442 LEU A CD2 1 ATOM 3529 N N . SER A 1 443 ? 62.495 62.932 -12.315 1.00 7.28 ? 443 SER A N 1 ATOM 3530 C CA . SER A 1 443 ? 63.604 62.867 -11.395 1.00 7.56 ? 443 SER A CA 1 ATOM 3531 C C . SER A 1 443 ? 64.004 61.458 -11.034 1.00 8.37 ? 443 SER A C 1 ATOM 3532 O O . SER A 1 443 ? 65.112 61.261 -10.497 1.00 9.30 ? 443 SER A O 1 ATOM 3533 C CB . SER A 1 443 ? 63.330 63.655 -10.144 1.00 7.53 ? 443 SER A CB 1 ATOM 3534 O OG . SER A 1 443 ? 62.207 63.160 -9.384 1.00 7.89 ? 443 SER A OG 1 ATOM 3535 N N . ALA A 1 444 ? 63.188 60.475 -11.344 1.00 7.72 ? 444 ALA A N 1 ATOM 3536 C CA . ALA A 1 444 ? 63.503 59.087 -11.019 1.00 8.51 ? 444 ALA A CA 1 ATOM 3537 C C . ALA A 1 444 ? 64.656 58.537 -11.833 1.00 9.33 ? 444 ALA A C 1 ATOM 3538 O O . ALA A 1 444 ? 65.263 57.559 -11.412 1.00 10.01 ? 444 ALA A O 1 ATOM 3539 C CB . ALA A 1 444 ? 62.280 58.175 -11.228 1.00 9.10 ? 444 ALA A CB 1 ATOM 3540 N N . TRP A 1 445 ? 64.915 59.107 -12.990 1.00 9.99 ? 445 TRP A N 1 ATOM 3541 C CA . TRP A 1 445 ? 65.970 58.551 -13.863 1.00 9.83 ? 445 TRP A CA 1 ATOM 3542 C C . TRP A 1 445 ? 67.358 58.626 -13.234 1.00 10.73 ? 445 TRP A C 1 ATOM 3543 O O . TRP A 1 445 ? 68.226 57.851 -13.659 1.00 12.36 ? 445 TRP A O 1 ATOM 3544 C CB . TRP A 1 445 ? 66.018 59.280 -15.220 1.00 9.68 ? 445 TRP A CB 1 ATOM 3545 C CG . TRP A 1 445 ? 64.711 59.136 -16.001 1.00 8.21 ? 445 TRP A CG 1 ATOM 3546 C CD1 . TRP A 1 445 ? 63.723 60.085 -16.145 1.00 8.66 ? 445 TRP A CD1 1 ATOM 3547 C CD2 . TRP A 1 445 ? 64.246 57.958 -16.667 1.00 7.86 ? 445 TRP A CD2 1 ATOM 3548 N NE1 . TRP A 1 445 ? 62.684 59.561 -16.839 1.00 8.71 ? 445 TRP A NE1 1 ATOM 3549 C CE2 . TRP A 1 445 ? 62.964 58.253 -17.172 1.00 8.06 ? 445 TRP A CE2 1 ATOM 3550 C CE3 . TRP A 1 445 ? 64.797 56.671 -16.878 1.00 9.30 ? 445 TRP A CE3 1 ATOM 3551 C CZ2 . TRP A 1 445 ? 62.203 57.331 -17.865 1.00 8.79 ? 445 TRP A CZ2 1 ATOM 3552 C CZ3 . TRP A 1 445 ? 64.052 55.734 -17.567 1.00 9.98 ? 445 TRP A CZ3 1 ATOM 3553 C CH2 . TRP A 1 445 ? 62.741 56.066 -18.062 1.00 9.72 ? 445 TRP A CH2 1 ATOM 3554 N N . HIS A 1 446 ? 67.556 59.547 -12.304 1.00 10.24 ? 446 HIS A N 1 ATOM 3555 C CA . HIS A 1 446 ? 68.855 59.646 -11.663 1.00 11.72 ? 446 HIS A CA 1 ATOM 3556 C C . HIS A 1 446 ? 68.736 59.619 -10.162 1.00 11.55 ? 446 HIS A C 1 ATOM 3557 O O . HIS A 1 446 ? 67.657 59.831 -9.584 1.00 10.85 ? 446 HIS A O 1 ATOM 3558 C CB . HIS A 1 446 ? 69.511 61.001 -11.935 1.00 12.87 ? 446 HIS A CB 1 ATOM 3559 C CG . HIS A 1 446 ? 69.887 61.255 -13.356 1.00 14.66 ? 446 HIS A CG 1 ATOM 3560 N ND1 . HIS A 1 446 ? 69.098 61.995 -14.207 1.00 16.20 ? 446 HIS A ND1 1 ATOM 3561 C CD2 . HIS A 1 446 ? 71.016 60.956 -14.057 1.00 17.69 ? 446 HIS A CD2 1 ATOM 3562 C CE1 . HIS A 1 446 ? 69.703 62.141 -15.369 1.00 19.27 ? 446 HIS A CE1 1 ATOM 3563 N NE2 . HIS A 1 446 ? 70.866 61.520 -15.310 1.00 17.94 ? 446 HIS A NE2 1 ATOM 3564 N N . SER A 1 447 ? 69.887 59.395 -9.529 1.00 12.10 ? 447 SER A N 1 ATOM 3565 C CA . SER A 1 447 ? 70.036 59.471 -8.090 1.00 11.72 ? 447 SER A CA 1 ATOM 3566 C C . SER A 1 447 ? 70.490 60.939 -7.869 1.00 12.24 ? 447 SER A C 1 ATOM 3567 O O . SER A 1 447 ? 71.304 61.474 -8.653 1.00 13.73 ? 447 SER A O 1 ATOM 3568 C CB A SER A 1 447 ? 71.123 58.491 -7.656 0.50 13.82 ? 447 SER A CB 1 ATOM 3569 C CB B SER A 1 447 ? 70.966 58.491 -7.462 0.50 13.94 ? 447 SER A CB 1 ATOM 3570 O OG A SER A 1 447 ? 71.128 58.353 -6.255 0.50 14.25 ? 447 SER A OG 1 ATOM 3571 O OG B SER A 1 447 ? 70.338 57.265 -7.162 0.50 15.03 ? 447 SER A OG 1 ATOM 3572 N N . TRP A 1 448 ? 69.957 61.616 -6.858 1.00 11.07 ? 448 TRP A N 1 ATOM 3573 C CA . TRP A 1 448 ? 70.293 63.006 -6.621 1.00 12.49 ? 448 TRP A CA 1 ATOM 3574 C C . TRP A 1 448 ? 70.946 63.212 -5.285 1.00 13.84 ? 448 TRP A C 1 ATOM 3575 O O . TRP A 1 448 ? 70.613 62.576 -4.302 1.00 14.74 ? 448 TRP A O 1 ATOM 3576 C CB . TRP A 1 448 ? 69.032 63.916 -6.678 1.00 10.97 ? 448 TRP A CB 1 ATOM 3577 C CG . TRP A 1 448 ? 68.389 63.909 -8.031 1.00 10.14 ? 448 TRP A CG 1 ATOM 3578 C CD1 . TRP A 1 448 ? 67.530 62.962 -8.538 1.00 10.64 ? 448 TRP A CD1 1 ATOM 3579 C CD2 . TRP A 1 448 ? 68.540 64.908 -9.038 1.00 9.75 ? 448 TRP A CD2 1 ATOM 3580 N NE1 . TRP A 1 448 ? 67.134 63.319 -9.816 1.00 10.45 ? 448 TRP A NE1 1 ATOM 3581 C CE2 . TRP A 1 448 ? 67.736 64.509 -10.135 1.00 10.47 ? 448 TRP A CE2 1 ATOM 3582 C CE3 . TRP A 1 448 ? 69.259 66.099 -9.114 1.00 11.00 ? 448 TRP A CE3 1 ATOM 3583 C CZ2 . TRP A 1 448 ? 67.642 65.257 -11.279 1.00 11.31 ? 448 TRP A CZ2 1 ATOM 3584 C CZ3 . TRP A 1 448 ? 69.153 66.863 -10.285 1.00 10.98 ? 448 TRP A CZ3 1 ATOM 3585 C CH2 . TRP A 1 448 ? 68.344 66.420 -11.342 1.00 10.02 ? 448 TRP A CH2 1 ATOM 3586 N N . ASP A 1 449 ? 71.920 64.104 -5.287 1.00 16.04 ? 449 ASP A N 1 ATOM 3587 C CA . ASP A 1 449 ? 72.566 64.450 -4.052 1.00 17.73 ? 449 ASP A CA 1 ATOM 3588 C C . ASP A 1 449 ? 71.548 65.106 -3.117 1.00 17.63 ? 449 ASP A C 1 ATOM 3589 O O . ASP A 1 449 ? 70.672 65.835 -3.555 1.00 16.39 ? 449 ASP A O 1 ATOM 3590 C CB . ASP A 1 449 ? 73.676 65.443 -4.371 1.00 21.12 ? 449 ASP A CB 1 ATOM 3591 C CG . ASP A 1 449 ? 74.521 65.760 -3.163 1.00 23.70 ? 449 ASP A CG 1 ATOM 3592 O OD1 . ASP A 1 449 ? 75.442 64.962 -2.886 1.00 28.43 ? 449 ASP A OD1 1 ATOM 3593 O OD2 . ASP A 1 449 ? 74.261 66.766 -2.481 1.00 25.34 ? 449 ASP A OD2 1 ATOM 3594 N N . GLY A 1 450 ? 71.695 64.901 -1.823 1.00 17.18 ? 450 GLY A N 1 ATOM 3595 C CA . GLY A 1 450 ? 70.783 65.526 -0.890 1.00 17.89 ? 450 GLY A CA 1 ATOM 3596 C C . GLY A 1 450 ? 70.669 67.024 -1.008 1.00 17.64 ? 450 GLY A C 1 ATOM 3597 O O . GLY A 1 450 ? 69.607 67.592 -0.693 1.00 18.13 ? 450 GLY A O 1 ATOM 3598 N N . MET A 1 451 ? 71.754 67.682 -1.450 1.00 17.08 ? 451 MET A N 1 ATOM 3599 C CA . MET A 1 451 ? 71.754 69.118 -1.584 1.00 18.06 ? 451 MET A CA 1 ATOM 3600 C C . MET A 1 451 ? 70.793 69.603 -2.652 1.00 15.53 ? 451 MET A C 1 ATOM 3601 O O . MET A 1 451 ? 70.419 70.786 -2.682 1.00 16.61 ? 451 MET A O 1 ATOM 3602 C CB . MET A 1 451 ? 73.174 69.612 -1.911 1.00 22.48 ? 451 MET A CB 1 ATOM 3603 C CG . MET A 1 451 ? 74.172 69.516 -0.767 1.00 27.71 ? 451 MET A CG 1 ATOM 3604 S SD . MET A 1 451 ? 73.681 70.472 0.719 1.00 36.08 ? 451 MET A SD 1 ATOM 3605 C CE . MET A 1 451 ? 73.076 69.101 1.838 1.00 33.09 ? 451 MET A CE 1 ATOM 3606 N N . ALA A 1 452 ? 70.370 68.685 -3.525 1.00 14.09 ? 452 ALA A N 1 ATOM 3607 C CA . ALA A 1 452 ? 69.445 69.088 -4.583 1.00 13.72 ? 452 ALA A CA 1 ATOM 3608 C C . ALA A 1 452 ? 68.026 69.221 -4.052 1.00 12.63 ? 452 ALA A C 1 ATOM 3609 O O . ALA A 1 452 ? 67.178 69.814 -4.749 1.00 14.52 ? 452 ALA A O 1 ATOM 3610 C CB . ALA A 1 452 ? 69.467 68.129 -5.722 1.00 13.00 ? 452 ALA A CB 1 ATOM 3611 N N . ARG A 1 453 ? 67.775 68.701 -2.839 1.00 12.53 ? 453 ARG A N 1 ATOM 3612 C CA . ARG A 1 453 ? 66.431 68.822 -2.224 1.00 13.11 ? 453 ARG A CA 1 ATOM 3613 C C . ARG A 1 453 ? 65.331 68.224 -3.103 1.00 12.10 ? 453 ARG A C 1 ATOM 3614 O O . ARG A 1 453 ? 64.188 68.689 -3.033 1.00 13.62 ? 453 ARG A O 1 ATOM 3615 C CB . ARG A 1 453 ? 66.135 70.277 -1.940 1.00 13.76 ? 453 ARG A CB 1 ATOM 3616 C CG . ARG A 1 453 ? 67.207 70.939 -1.030 1.00 16.23 ? 453 ARG A CG 1 ATOM 3617 C CD . ARG A 1 453 ? 66.924 72.448 -0.827 1.00 19.20 ? 453 ARG A CD 1 ATOM 3618 N NE . ARG A 1 453 ? 65.756 72.684 0.015 1.00 20.37 ? 453 ARG A NE 1 ATOM 3619 C CZ . ARG A 1 453 ? 65.271 73.895 0.279 1.00 21.05 ? 453 ARG A CZ 1 ATOM 3620 N NH1 . ARG A 1 453 ? 65.861 74.989 -0.230 1.00 22.22 ? 453 ARG A NH1 1 ATOM 3621 N NH2 . ARG A 1 453 ? 64.183 74.013 1.023 1.00 22.90 ? 453 ARG A NH2 1 ATOM 3622 N N . ILE A 1 454 ? 65.643 67.198 -3.871 1.00 10.98 ? 454 ILE A N 1 ATOM 3623 C CA . ILE A 1 454 ? 64.637 66.587 -4.725 1.00 10.69 ? 454 ILE A CA 1 ATOM 3624 C C . ILE A 1 454 ? 63.643 65.808 -3.862 1.00 11.13 ? 454 ILE A C 1 ATOM 3625 O O . ILE A 1 454 ? 62.408 66.043 -3.981 1.00 10.06 ? 454 ILE A O 1 ATOM 3626 C CB . ILE A 1 454 ? 65.320 65.652 -5.730 1.00 10.22 ? 454 ILE A CB 1 ATOM 3627 C CG1 . ILE A 1 454 ? 66.257 66.468 -6.647 1.00 12.32 ? 454 ILE A CG1 1 ATOM 3628 C CG2 . ILE A 1 454 ? 64.236 64.826 -6.473 1.00 11.13 ? 454 ILE A CG2 1 ATOM 3629 C CD1 . ILE A 1 454 ? 65.552 67.488 -7.549 1.00 12.39 ? 454 ILE A CD1 1 ATOM 3630 N N . GLU A 1 455 ? 64.093 64.938 -2.970 1.00 11.02 ? 455 GLU A N 1 ATOM 3631 C CA . GLU A 1 455 ? 63.151 64.166 -2.128 1.00 11.00 ? 455 GLU A CA 1 ATOM 3632 C C . GLU A 1 455 ? 62.327 65.099 -1.271 1.00 10.40 ? 455 GLU A C 1 ATOM 3633 O O . GLU A 1 455 ? 61.122 64.853 -1.085 1.00 10.57 ? 455 GLU A O 1 ATOM 3634 C CB . GLU A 1 455 ? 63.916 63.176 -1.226 1.00 12.38 ? 455 GLU A CB 1 ATOM 3635 C CG . GLU A 1 455 ? 64.525 61.979 -1.962 1.00 12.97 ? 455 GLU A CG 1 ATOM 3636 C CD . GLU A 1 455 ? 65.937 62.264 -2.570 1.00 12.16 ? 455 GLU A CD 1 ATOM 3637 O OE1 . GLU A 1 455 ? 66.395 63.425 -2.481 1.00 13.46 ? 455 GLU A OE1 1 ATOM 3638 O OE2 . GLU A 1 455 ? 66.484 61.296 -3.103 1.00 12.62 ? 455 GLU A OE2 1 ATOM 3639 N N . GLU A 1 456 ? 62.898 66.163 -0.749 1.00 11.16 ? 456 GLU A N 1 ATOM 3640 C CA . GLU A 1 456 ? 62.185 67.117 0.072 1.00 10.47 ? 456 GLU A CA 1 ATOM 3641 C C . GLU A 1 456 ? 61.029 67.754 -0.693 1.00 10.21 ? 456 GLU A C 1 ATOM 3642 O O . GLU A 1 456 ? 59.879 67.828 -0.209 1.00 10.10 ? 456 GLU A O 1 ATOM 3643 C CB . GLU A 1 456 ? 63.197 68.203 0.542 1.00 12.19 ? 456 GLU A CB 1 ATOM 3644 C CG . GLU A 1 456 ? 62.584 69.331 1.322 1.00 15.41 ? 456 GLU A CG 1 ATOM 3645 C CD . GLU A 1 456 ? 63.503 70.550 1.550 1.00 17.98 ? 456 GLU A CD 1 ATOM 3646 O OE1 . GLU A 1 456 ? 64.735 70.444 1.323 1.00 20.00 ? 456 GLU A OE1 1 ATOM 3647 O OE2 . GLU A 1 456 ? 62.987 71.623 1.973 1.00 20.33 ? 456 GLU A OE2 1 ATOM 3648 N N . ARG A 1 457 ? 61.296 68.233 -1.906 1.00 9.53 ? 457 ARG A N 1 ATOM 3649 C CA . ARG A 1 457 ? 60.232 68.889 -2.673 1.00 8.69 ? 457 ARG A CA 1 ATOM 3650 C C . ARG A 1 457 ? 59.171 67.885 -3.127 1.00 8.34 ? 457 ARG A C 1 ATOM 3651 O O . ARG A 1 457 ? 57.973 68.235 -3.118 1.00 8.79 ? 457 ARG A O 1 ATOM 3652 C CB . ARG A 1 457 ? 60.847 69.642 -3.886 1.00 9.57 ? 457 ARG A CB 1 ATOM 3653 C CG . ARG A 1 457 ? 61.140 71.099 -3.653 1.00 11.67 ? 457 ARG A CG 1 ATOM 3654 C CD . ARG A 1 457 ? 62.179 71.329 -2.597 1.00 12.79 ? 457 ARG A CD 1 ATOM 3655 N NE . ARG A 1 457 ? 62.352 72.763 -2.250 1.00 15.59 ? 457 ARG A NE 1 ATOM 3656 C CZ . ARG A 1 457 ? 63.248 73.569 -2.830 1.00 17.87 ? 457 ARG A CZ 1 ATOM 3657 N NH1 . ARG A 1 457 ? 64.073 73.107 -3.793 1.00 16.88 ? 457 ARG A NH1 1 ATOM 3658 N NH2 . ARG A 1 457 ? 63.327 74.841 -2.443 1.00 18.85 ? 457 ARG A NH2 1 ATOM 3659 N N . LEU A 1 458 ? 59.561 66.683 -3.487 1.00 7.89 ? 458 LEU A N 1 ATOM 3660 C CA . LEU A 1 458 ? 58.556 65.675 -3.902 1.00 8.34 ? 458 LEU A CA 1 ATOM 3661 C C . LEU A 1 458 ? 57.723 65.272 -2.716 1.00 8.97 ? 458 LEU A C 1 ATOM 3662 O O . LEU A 1 458 ? 56.498 65.093 -2.878 1.00 8.80 ? 458 LEU A O 1 ATOM 3663 C CB . LEU A 1 458 ? 59.228 64.468 -4.509 1.00 8.38 ? 458 LEU A CB 1 ATOM 3664 C CG . LEU A 1 458 ? 59.944 64.785 -5.863 1.00 8.06 ? 458 LEU A CG 1 ATOM 3665 C CD1 . LEU A 1 458 ? 60.711 63.581 -6.274 1.00 10.68 ? 458 LEU A CD1 1 ATOM 3666 C CD2 . LEU A 1 458 ? 58.920 65.215 -6.996 1.00 10.00 ? 458 LEU A CD2 1 ATOM 3667 N N . GLU A 1 459 ? 58.301 65.149 -1.511 1.00 8.64 ? 459 GLU A N 1 ATOM 3668 C CA . GLU A 1 459 ? 57.468 64.758 -0.368 1.00 8.98 ? 459 GLU A CA 1 ATOM 3669 C C . GLU A 1 459 ? 56.453 65.876 -0.080 1.00 9.15 ? 459 GLU A C 1 ATOM 3670 O O . GLU A 1 459 ? 55.256 65.597 0.185 1.00 8.99 ? 459 GLU A O 1 ATOM 3671 C CB . GLU A 1 459 ? 58.379 64.540 0.842 1.00 9.08 ? 459 GLU A CB 1 ATOM 3672 C CG . GLU A 1 459 ? 57.574 64.197 2.116 1.00 13.09 ? 459 GLU A CG 1 ATOM 3673 C CD . GLU A 1 459 ? 58.459 63.567 3.170 1.00 15.82 ? 459 GLU A CD 1 ATOM 3674 O OE1 . GLU A 1 459 ? 59.077 64.361 3.878 1.00 20.13 ? 459 GLU A OE1 1 ATOM 3675 O OE2 . GLU A 1 459 ? 58.561 62.332 3.250 1.00 18.35 ? 459 GLU A OE2 1 ATOM 3676 N N . GLN A 1 460 ? 56.876 67.134 -0.156 1.00 8.33 ? 460 GLN A N 1 ATOM 3677 C CA . GLN A 1 460 ? 55.937 68.224 0.063 1.00 9.33 ? 460 GLN A CA 1 ATOM 3678 C C . GLN A 1 460 ? 54.806 68.141 -0.981 1.00 9.27 ? 460 GLN A C 1 ATOM 3679 O O . GLN A 1 460 ? 53.615 68.243 -0.672 1.00 9.15 ? 460 GLN A O 1 ATOM 3680 C CB . GLN A 1 460 ? 56.654 69.562 -0.087 1.00 11.26 ? 460 GLN A CB 1 ATOM 3681 C CG . GLN A 1 460 ? 55.755 70.780 0.088 1.00 16.38 ? 460 GLN A CG 1 ATOM 3682 C CD . GLN A 1 460 ? 56.551 72.093 -0.166 1.00 19.74 ? 460 GLN A CD 1 ATOM 3683 O OE1 . GLN A 1 460 ? 56.150 73.138 0.272 1.00 25.32 ? 460 GLN A OE1 1 ATOM 3684 N NE2 . GLN A 1 460 ? 57.641 72.003 -0.922 1.00 22.30 ? 460 GLN A NE2 1 ATOM 3685 N N . ALA A 1 461 ? 55.172 67.984 -2.242 1.00 8.01 ? 461 ALA A N 1 ATOM 3686 C CA . ALA A 1 461 ? 54.115 67.936 -3.259 1.00 8.13 ? 461 ALA A CA 1 ATOM 3687 C C . ALA A 1 461 ? 53.137 66.776 -3.090 1.00 7.49 ? 461 ALA A C 1 ATOM 3688 O O . ALA A 1 461 ? 51.915 66.983 -3.172 1.00 8.12 ? 461 ALA A O 1 ATOM 3689 C CB . ALA A 1 461 ? 54.784 67.935 -4.661 1.00 8.77 ? 461 ALA A CB 1 ATOM 3690 N N . ARG A 1 462 ? 53.658 65.588 -2.816 1.00 7.76 ? 462 ARG A N 1 ATOM 3691 C CA . ARG A 1 462 ? 52.800 64.436 -2.600 1.00 7.49 ? 462 ARG A CA 1 ATOM 3692 C C . ARG A 1 462 ? 51.893 64.685 -1.395 1.00 7.27 ? 462 ARG A C 1 ATOM 3693 O O . ARG A 1 462 ? 50.686 64.309 -1.437 1.00 7.42 ? 462 ARG A O 1 ATOM 3694 C CB . ARG A 1 462 ? 53.572 63.152 -2.325 1.00 8.12 ? 462 ARG A CB 1 ATOM 3695 C CG . ARG A 1 462 ? 54.309 62.572 -3.564 1.00 7.05 ? 462 ARG A CG 1 ATOM 3696 C CD . ARG A 1 462 ? 54.802 61.161 -3.304 1.00 8.11 ? 462 ARG A CD 1 ATOM 3697 N NE . ARG A 1 462 ? 55.685 61.119 -2.123 1.00 7.94 ? 462 ARG A NE 1 ATOM 3698 C CZ . ARG A 1 462 ? 57.001 61.264 -2.191 1.00 9.36 ? 462 ARG A CZ 1 ATOM 3699 N NH1 . ARG A 1 462 ? 57.605 61.424 -3.354 1.00 9.98 ? 462 ARG A NH1 1 ATOM 3700 N NH2 . ARG A 1 462 ? 57.723 61.273 -1.081 1.00 11.16 ? 462 ARG A NH2 1 ATOM 3701 N N . ARG A 1 463 ? 52.421 65.305 -0.332 1.00 7.50 ? 463 ARG A N 1 ATOM 3702 C CA . ARG A 1 463 ? 51.585 65.464 0.858 1.00 7.25 ? 463 ARG A CA 1 ATOM 3703 C C . ARG A 1 463 ? 50.523 66.532 0.690 1.00 7.44 ? 463 ARG A C 1 ATOM 3704 O O . ARG A 1 463 ? 49.389 66.356 1.213 1.00 8.26 ? 463 ARG A O 1 ATOM 3705 C CB . ARG A 1 463 ? 52.485 65.725 2.089 1.00 7.76 ? 463 ARG A CB 1 ATOM 3706 C CG . ARG A 1 463 ? 53.178 64.448 2.494 1.00 8.48 ? 463 ARG A CG 1 ATOM 3707 C CD . ARG A 1 463 ? 54.224 64.709 3.606 1.00 11.00 ? 463 ARG A CD 1 ATOM 3708 N NE . ARG A 1 463 ? 54.727 63.383 3.966 1.00 11.74 ? 463 ARG A NE 1 ATOM 3709 C CZ . ARG A 1 463 ? 55.485 63.134 5.020 1.00 14.58 ? 463 ARG A CZ 1 ATOM 3710 N NH1 . ARG A 1 463 ? 55.850 64.131 5.793 1.00 15.08 ? 463 ARG A NH1 1 ATOM 3711 N NH2 . ARG A 1 463 ? 55.799 61.854 5.277 1.00 15.28 ? 463 ARG A NH2 1 ATOM 3712 N N . GLU A 1 464 ? 50.767 67.626 -0.052 1.00 7.46 ? 464 GLU A N 1 ATOM 3713 C CA . GLU A 1 464 ? 49.733 68.628 -0.178 1.00 7.66 ? 464 GLU A CA 1 ATOM 3714 C C . GLU A 1 464 ? 48.649 68.097 -1.099 1.00 8.14 ? 464 GLU A C 1 ATOM 3715 O O . GLU A 1 464 ? 47.460 68.346 -0.854 1.00 8.03 ? 464 GLU A O 1 ATOM 3716 C CB . GLU A 1 464 ? 50.264 69.953 -0.768 1.00 9.72 ? 464 GLU A CB 1 ATOM 3717 C CG . GLU A 1 464 ? 51.465 70.623 0.015 1.00 11.81 ? 464 GLU A CG 1 ATOM 3718 C CD . GLU A 1 464 ? 51.194 71.009 1.473 1.00 16.04 ? 464 GLU A CD 1 ATOM 3719 O OE1 . GLU A 1 464 ? 50.232 70.551 2.072 1.00 15.35 ? 464 GLU A OE1 1 ATOM 3720 O OE2 . GLU A 1 464 ? 52.025 71.796 1.990 1.00 19.55 ? 464 GLU A OE2 1 ATOM 3721 N N . LEU A 1 465 ? 49.035 67.374 -2.155 1.00 6.98 ? 465 LEU A N 1 ATOM 3722 C CA . LEU A 1 465 ? 47.996 66.798 -3.049 1.00 6.73 ? 465 LEU A CA 1 ATOM 3723 C C . LEU A 1 465 ? 47.227 65.727 -2.278 1.00 6.91 ? 465 LEU A C 1 ATOM 3724 O O . LEU A 1 465 ? 45.962 65.638 -2.387 1.00 7.19 ? 465 LEU A O 1 ATOM 3725 C CB . LEU A 1 465 ? 48.639 66.207 -4.317 1.00 7.09 ? 465 LEU A CB 1 ATOM 3726 C CG . LEU A 1 465 ? 47.634 65.526 -5.289 1.00 7.40 ? 465 LEU A CG 1 ATOM 3727 C CD1 . LEU A 1 465 ? 46.565 66.552 -5.770 1.00 8.10 ? 465 LEU A CD1 1 ATOM 3728 C CD2 . LEU A 1 465 ? 48.412 64.986 -6.503 1.00 8.18 ? 465 LEU A CD2 1 ATOM 3729 N N . SER A 1 466 ? 47.933 64.929 -1.452 1.00 6.42 ? 466 SER A N 1 ATOM 3730 C CA . SER A 1 466 ? 47.235 63.893 -0.682 1.00 6.21 ? 466 SER A CA 1 ATOM 3731 C C . SER A 1 466 ? 46.246 64.500 0.316 1.00 6.43 ? 466 SER A C 1 ATOM 3732 O O . SER A 1 466 ? 45.117 63.984 0.455 1.00 6.72 ? 466 SER A O 1 ATOM 3733 C CB . SER A 1 466 ? 48.255 63.055 0.069 1.00 6.51 ? 466 SER A CB 1 ATOM 3734 O OG . SER A 1 466 ? 49.003 62.229 -0.831 1.00 7.26 ? 466 SER A OG 1 ATOM 3735 N N . LEU A 1 467 ? 46.634 65.597 0.966 1.00 6.10 ? 467 LEU A N 1 ATOM 3736 C CA . LEU A 1 467 ? 45.727 66.259 1.919 1.00 6.79 ? 467 LEU A CA 1 ATOM 3737 C C . LEU A 1 467 ? 44.449 66.690 1.230 1.00 5.83 ? 467 LEU A C 1 ATOM 3738 O O . LEU A 1 467 ? 43.363 66.537 1.800 1.00 6.38 ? 467 LEU A O 1 ATOM 3739 C CB . LEU A 1 467 ? 46.484 67.452 2.523 1.00 7.92 ? 467 LEU A CB 1 ATOM 3740 C CG . LEU A 1 467 ? 45.656 68.194 3.566 1.00 9.97 ? 467 LEU A CG 1 ATOM 3741 C CD1 . LEU A 1 467 ? 45.618 67.345 4.809 1.00 15.33 ? 467 LEU A CD1 1 ATOM 3742 C CD2 . LEU A 1 467 ? 46.317 69.545 3.861 1.00 11.02 ? 467 LEU A CD2 1 ATOM 3743 N N . PHE A 1 468 ? 44.562 67.187 -0.003 1.00 6.01 ? 468 PHE A N 1 ATOM 3744 C CA . PHE A 1 468 ? 43.389 67.697 -0.699 1.00 5.99 ? 468 PHE A CA 1 ATOM 3745 C C . PHE A 1 468 ? 42.426 66.597 -1.074 1.00 6.07 ? 468 PHE A C 1 ATOM 3746 O O . PHE A 1 468 ? 41.247 66.902 -1.373 1.00 6.94 ? 468 PHE A O 1 ATOM 3747 C CB . PHE A 1 468 ? 43.821 68.488 -1.954 1.00 7.02 ? 468 PHE A CB 1 ATOM 3748 C CG . PHE A 1 468 ? 42.699 69.328 -2.511 1.00 5.80 ? 468 PHE A CG 1 ATOM 3749 C CD1 . PHE A 1 468 ? 42.039 70.254 -1.733 1.00 7.11 ? 468 PHE A CD1 1 ATOM 3750 C CD2 . PHE A 1 468 ? 42.271 69.135 -3.815 1.00 7.04 ? 468 PHE A CD2 1 ATOM 3751 C CE1 . PHE A 1 468 ? 40.969 70.988 -2.211 1.00 7.03 ? 468 PHE A CE1 1 ATOM 3752 C CE2 . PHE A 1 468 ? 41.198 69.877 -4.308 1.00 6.57 ? 468 PHE A CE2 1 ATOM 3753 C CZ . PHE A 1 468 ? 40.545 70.807 -3.506 1.00 7.04 ? 468 PHE A CZ 1 ATOM 3754 N N . GLN A 1 469 ? 42.851 65.324 -1.061 1.00 5.56 ? 469 GLN A N 1 ATOM 3755 C CA . GLN A 1 469 ? 41.884 64.258 -1.320 1.00 5.71 ? 469 GLN A CA 1 ATOM 3756 C C . GLN A 1 469 ? 40.873 64.083 -0.206 1.00 6.11 ? 469 GLN A C 1 ATOM 3757 O O . GLN A 1 469 ? 39.910 63.312 -0.380 1.00 6.51 ? 469 GLN A O 1 ATOM 3758 C CB . GLN A 1 469 ? 42.618 62.910 -1.516 1.00 6.16 ? 469 GLN A CB 1 ATOM 3759 C CG . GLN A 1 469 ? 43.741 62.977 -2.642 1.00 6.22 ? 469 GLN A CG 1 ATOM 3760 C CD . GLN A 1 469 ? 43.257 63.676 -3.909 1.00 6.12 ? 469 GLN A CD 1 ATOM 3761 O OE1 . GLN A 1 469 ? 43.800 64.728 -4.357 1.00 8.71 ? 469 GLN A OE1 1 ATOM 3762 N NE2 . GLN A 1 469 ? 42.230 63.147 -4.456 1.00 4.65 ? 469 GLN A NE2 1 ATOM 3763 N N . HIS A 1 470 ? 41.080 64.751 0.922 1.00 5.58 ? 470 HIS A N 1 ATOM 3764 C CA . HIS A 1 470 ? 40.127 64.680 2.024 1.00 5.60 ? 470 HIS A CA 1 ATOM 3765 C C . HIS A 1 470 ? 38.696 64.935 1.527 1.00 6.33 ? 470 HIS A C 1 ATOM 3766 O O . HIS A 1 470 ? 38.483 65.684 0.567 1.00 6.45 ? 470 HIS A O 1 ATOM 3767 C CB . HIS A 1 470 ? 40.529 65.726 3.074 1.00 6.44 ? 470 HIS A CB 1 ATOM 3768 C CG . HIS A 1 470 ? 39.499 65.883 4.139 1.00 6.47 ? 470 HIS A CG 1 ATOM 3769 N ND1 . HIS A 1 470 ? 39.025 67.098 4.591 1.00 8.71 ? 470 HIS A ND1 1 ATOM 3770 C CD2 . HIS A 1 470 ? 38.854 64.923 4.849 1.00 4.79 ? 470 HIS A CD2 1 ATOM 3771 C CE1 . HIS A 1 470 ? 38.123 66.866 5.548 1.00 5.97 ? 470 HIS A CE1 1 ATOM 3772 N NE2 . HIS A 1 470 ? 38.015 65.559 5.704 1.00 10.00 ? 470 HIS A NE2 1 ATOM 3773 N N . HIS A 1 471 ? 37.730 64.306 2.218 1.00 6.50 ? 471 HIS A N 1 ATOM 3774 C CA . HIS A 1 471 ? 36.337 64.423 1.866 1.00 6.21 ? 471 HIS A CA 1 ATOM 3775 C C . HIS A 1 471 ? 35.683 65.789 2.155 1.00 6.73 ? 471 HIS A C 1 ATOM 3776 O O . HIS A 1 471 ? 34.487 65.920 1.924 1.00 7.69 ? 471 HIS A O 1 ATOM 3777 C CB . HIS A 1 471 ? 35.559 63.254 2.464 1.00 5.83 ? 471 HIS A CB 1 ATOM 3778 C CG . HIS A 1 471 ? 35.625 63.187 3.951 1.00 5.23 ? 471 HIS A CG 1 ATOM 3779 N ND1 . HIS A 1 471 ? 36.571 62.456 4.627 1.00 6.50 ? 471 HIS A ND1 1 ATOM 3780 C CD2 . HIS A 1 471 ? 34.875 63.808 4.883 1.00 6.23 ? 471 HIS A CD2 1 ATOM 3781 C CE1 . HIS A 1 471 ? 36.403 62.636 5.935 1.00 6.03 ? 471 HIS A CE1 1 ATOM 3782 N NE2 . HIS A 1 471 ? 35.372 63.445 6.128 1.00 6.63 ? 471 HIS A NE2 1 ATOM 3783 N N . ASP A 1 472 ? 36.464 66.780 2.643 1.00 7.14 ? 472 ASP A N 1 ATOM 3784 C CA . ASP A 1 472 ? 35.984 68.174 2.602 1.00 6.81 ? 472 ASP A CA 1 ATOM 3785 C C . ASP A 1 472 ? 36.993 69.028 1.808 1.00 7.55 ? 472 ASP A C 1 ATOM 3786 O O . ASP A 1 472 ? 36.846 70.269 1.809 1.00 8.02 ? 472 ASP A O 1 ATOM 3787 C CB . ASP A 1 472 ? 35.741 68.817 3.965 1.00 7.64 ? 472 ASP A CB 1 ATOM 3788 C CG . ASP A 1 472 ? 34.674 68.088 4.777 1.00 7.32 ? 472 ASP A CG 1 ATOM 3789 O OD1 . ASP A 1 472 ? 33.472 68.179 4.365 1.00 8.10 ? 472 ASP A OD1 1 ATOM 3790 O OD2 . ASP A 1 472 ? 35.097 67.430 5.747 1.00 7.91 ? 472 ASP A OD2 1 ATOM 3791 N N . GLY A 1 473 ? 37.937 68.411 1.084 1.00 6.51 ? 473 GLY A N 1 ATOM 3792 C CA . GLY A 1 473 ? 38.914 69.185 0.300 1.00 7.34 ? 473 GLY A CA 1 ATOM 3793 C C . GLY A 1 473 ? 38.442 69.251 -1.153 1.00 5.91 ? 473 GLY A C 1 ATOM 3794 O O . GLY A 1 473 ? 37.729 70.178 -1.528 1.00 7.28 ? 473 GLY A O 1 ATOM 3795 N N . ILE A 1 474 ? 38.769 68.214 -1.929 1.00 6.33 ? 474 ILE A N 1 ATOM 3796 C CA . ILE A 1 474 ? 38.331 68.210 -3.335 1.00 6.28 ? 474 ILE A CA 1 ATOM 3797 C C . ILE A 1 474 ? 36.819 68.318 -3.515 1.00 6.16 ? 474 ILE A C 1 ATOM 3798 O O . ILE A 1 474 ? 36.386 68.804 -4.548 1.00 7.01 ? 474 ILE A O 1 ATOM 3799 C CB . ILE A 1 474 ? 38.949 66.939 -4.030 1.00 6.19 ? 474 ILE A CB 1 ATOM 3800 C CG1 . ILE A 1 474 ? 38.685 66.995 -5.536 1.00 7.19 ? 474 ILE A CG1 1 ATOM 3801 C CG2 . ILE A 1 474 ? 38.381 65.609 -3.383 1.00 7.56 ? 474 ILE A CG2 1 ATOM 3802 C CD1 . ILE A 1 474 ? 39.411 65.806 -6.293 1.00 8.72 ? 474 ILE A CD1 1 ATOM 3803 N N . THR A 1 475 ? 36.078 67.867 -2.511 1.00 5.70 ? 475 THR A N 1 ATOM 3804 C CA . THR A 1 475 ? 34.610 67.967 -2.549 1.00 7.11 ? 475 THR A CA 1 ATOM 3805 C C . THR A 1 475 ? 34.088 69.419 -2.547 1.00 6.07 ? 475 THR A C 1 ATOM 3806 O O . THR A 1 475 ? 32.917 69.647 -2.880 1.00 6.94 ? 475 THR A O 1 ATOM 3807 C CB . THR A 1 475 ? 34.037 67.296 -1.293 1.00 7.09 ? 475 THR A CB 1 ATOM 3808 O OG1 . THR A 1 475 ? 34.566 68.032 -0.166 1.00 7.83 ? 475 THR A OG1 1 ATOM 3809 C CG2 . THR A 1 475 ? 34.431 65.828 -1.196 1.00 7.83 ? 475 THR A CG2 1 ATOM 3810 N N . GLY A 1 476 ? 34.919 70.390 -2.193 1.00 6.85 ? 476 GLY A N 1 ATOM 3811 C CA . GLY A 1 476 ? 34.420 71.773 -2.192 1.00 7.06 ? 476 GLY A CA 1 ATOM 3812 C C . GLY A 1 476 ? 33.460 72.061 -1.032 1.00 7.14 ? 476 GLY A C 1 ATOM 3813 O O . GLY A 1 476 ? 32.571 72.893 -1.176 1.00 7.73 ? 476 GLY A O 1 ATOM 3814 N N . THR A 1 477 ? 33.633 71.342 0.072 1.00 7.05 ? 477 THR A N 1 ATOM 3815 C CA . THR A 1 477 ? 32.749 71.501 1.192 1.00 7.74 ? 477 THR A CA 1 ATOM 3816 C C . THR A 1 477 ? 33.361 72.072 2.465 1.00 6.94 ? 477 THR A C 1 ATOM 3817 O O . THR A 1 477 ? 32.805 71.906 3.547 1.00 9.41 ? 477 THR A O 1 ATOM 3818 C CB . THR A 1 477 ? 32.048 70.155 1.529 1.00 7.34 ? 477 THR A CB 1 ATOM 3819 O OG1 . THR A 1 477 ? 33.017 69.124 1.788 1.00 7.14 ? 477 THR A OG1 1 ATOM 3820 C CG2 . THR A 1 477 ? 31.200 69.698 0.322 1.00 7.83 ? 477 THR A CG2 1 ATOM 3821 N N . ALA A 1 478 ? 34.458 72.820 2.342 1.00 6.94 ? 478 ALA A N 1 ATOM 3822 C CA . ALA A 1 478 ? 35.099 73.430 3.529 1.00 7.41 ? 478 ALA A CA 1 ATOM 3823 C C . ALA A 1 478 ? 34.819 74.938 3.581 1.00 7.43 ? 478 ALA A C 1 ATOM 3824 O O . ALA A 1 478 ? 34.318 75.574 2.632 1.00 7.98 ? 478 ALA A O 1 ATOM 3825 C CB . ALA A 1 478 ? 36.663 73.192 3.489 1.00 7.88 ? 478 ALA A CB 1 ATOM 3826 N N . LYS A 1 479 ? 35.108 75.529 4.742 1.00 7.71 ? 479 LYS A N 1 ATOM 3827 C CA . LYS A 1 479 ? 34.867 76.979 4.853 1.00 8.61 ? 479 LYS A CA 1 ATOM 3828 C C . LYS A 1 479 ? 35.816 77.735 3.931 1.00 8.18 ? 479 LYS A C 1 ATOM 3829 O O . LYS A 1 479 ? 36.887 77.229 3.556 1.00 7.77 ? 479 LYS A O 1 ATOM 3830 C CB . LYS A 1 479 ? 35.074 77.427 6.309 1.00 9.39 ? 479 LYS A CB 1 ATOM 3831 C CG . LYS A 1 479 ? 33.821 77.117 7.204 1.00 12.09 ? 479 LYS A CG 1 ATOM 3832 C CD . LYS A 1 479 ? 33.931 77.853 8.514 1.00 13.27 ? 479 LYS A CD 1 ATOM 3833 C CE . LYS A 1 479 ? 32.643 77.731 9.376 1.00 15.79 ? 479 LYS A CE 1 ATOM 3834 N NZ . LYS A 1 479 ? 31.411 78.384 8.772 1.00 16.59 ? 479 LYS A NZ 1 ATOM 3835 N N . THR A 1 480 ? 35.457 78.963 3.592 1.00 8.70 ? 480 THR A N 1 ATOM 3836 C CA . THR A 1 480 ? 36.236 79.751 2.681 1.00 9.23 ? 480 THR A CA 1 ATOM 3837 C C . THR A 1 480 ? 37.699 79.844 3.050 1.00 9.11 ? 480 THR A C 1 ATOM 3838 O O . THR A 1 480 ? 38.566 79.662 2.155 1.00 9.27 ? 480 THR A O 1 ATOM 3839 C CB . THR A 1 480 ? 35.646 81.154 2.621 1.00 10.54 ? 480 THR A CB 1 ATOM 3840 O OG1 . THR A 1 480 ? 34.311 81.049 2.120 1.00 13.17 ? 480 THR A OG1 1 ATOM 3841 C CG2 . THR A 1 480 ? 36.416 82.062 1.684 1.00 13.00 ? 480 THR A CG2 1 ATOM 3842 N N . HIS A 1 481 ? 38.057 80.132 4.314 1.00 8.72 ? 481 HIS A N 1 ATOM 3843 C CA . HIS A 1 481 ? 39.481 80.245 4.613 1.00 8.13 ? 481 HIS A CA 1 ATOM 3844 C C . HIS A 1 481 ? 40.230 78.918 4.565 1.00 9.10 ? 481 HIS A C 1 ATOM 3845 O O . HIS A 1 481 ? 41.448 78.876 4.427 1.00 9.67 ? 481 HIS A O 1 ATOM 3846 C CB . HIS A 1 481 ? 39.687 80.957 5.997 1.00 9.93 ? 481 HIS A CB 1 ATOM 3847 C CG . HIS A 1 481 ? 39.521 80.056 7.183 1.00 9.83 ? 481 HIS A CG 1 ATOM 3848 N ND1 . HIS A 1 481 ? 38.287 79.612 7.647 1.00 11.67 ? 481 HIS A ND1 1 ATOM 3849 C CD2 . HIS A 1 481 ? 40.455 79.538 8.015 1.00 10.56 ? 481 HIS A CD2 1 ATOM 3850 C CE1 . HIS A 1 481 ? 38.491 78.868 8.717 1.00 10.63 ? 481 HIS A CE1 1 ATOM 3851 N NE2 . HIS A 1 481 ? 39.788 78.811 8.961 1.00 11.86 ? 481 HIS A NE2 1 ATOM 3852 N N . VAL A 1 482 ? 39.471 77.803 4.682 1.00 8.43 ? 482 VAL A N 1 ATOM 3853 C CA . VAL A 1 482 ? 40.071 76.459 4.593 1.00 8.34 ? 482 VAL A CA 1 ATOM 3854 C C . VAL A 1 482 ? 40.331 76.151 3.115 1.00 7.12 ? 482 VAL A C 1 ATOM 3855 O O . VAL A 1 482 ? 41.400 75.609 2.800 1.00 7.42 ? 482 VAL A O 1 ATOM 3856 C CB . VAL A 1 482 ? 39.122 75.428 5.244 1.00 7.17 ? 482 VAL A CB 1 ATOM 3857 C CG1 . VAL A 1 482 ? 39.775 74.030 5.219 1.00 8.81 ? 482 VAL A CG1 1 ATOM 3858 C CG2 . VAL A 1 482 ? 38.919 75.789 6.775 1.00 8.87 ? 482 VAL A CG2 1 ATOM 3859 N N . VAL A 1 483 ? 39.395 76.493 2.236 1.00 7.28 ? 483 VAL A N 1 ATOM 3860 C CA . VAL A 1 483 ? 39.649 76.357 0.801 1.00 7.56 ? 483 VAL A CA 1 ATOM 3861 C C . VAL A 1 483 ? 40.903 77.159 0.409 1.00 7.55 ? 483 VAL A C 1 ATOM 3862 O O . VAL A 1 483 ? 41.754 76.642 -0.348 1.00 8.08 ? 483 VAL A O 1 ATOM 3863 C CB . VAL A 1 483 ? 38.449 76.865 0.006 1.00 7.21 ? 483 VAL A CB 1 ATOM 3864 C CG1 . VAL A 1 483 ? 38.735 76.850 -1.511 1.00 8.96 ? 483 VAL A CG1 1 ATOM 3865 C CG2 . VAL A 1 483 ? 37.218 75.972 0.326 1.00 8.46 ? 483 VAL A CG2 1 ATOM 3866 N N . VAL A 1 484 ? 41.091 78.365 0.992 1.00 8.75 ? 484 VAL A N 1 ATOM 3867 C CA . VAL A 1 484 ? 42.282 79.181 0.687 1.00 9.74 ? 484 VAL A CA 1 ATOM 3868 C C . VAL A 1 484 ? 43.509 78.438 1.159 1.00 8.70 ? 484 VAL A C 1 ATOM 3869 O O . VAL A 1 484 ? 44.514 78.418 0.430 1.00 8.87 ? 484 VAL A O 1 ATOM 3870 C CB . VAL A 1 484 ? 42.171 80.533 1.367 1.00 10.77 ? 484 VAL A CB 1 ATOM 3871 C CG1 . VAL A 1 484 ? 43.548 81.276 1.292 1.00 11.61 ? 484 VAL A CG1 1 ATOM 3872 C CG2 . VAL A 1 484 ? 41.114 81.354 0.650 1.00 12.29 ? 484 VAL A CG2 1 ATOM 3873 N N . ASP A 1 485 ? 43.468 77.798 2.334 1.00 8.78 ? 485 ASP A N 1 ATOM 3874 C CA . ASP A 1 485 ? 44.628 77.038 2.794 1.00 8.22 ? 485 ASP A CA 1 ATOM 3875 C C . ASP A 1 485 ? 44.969 75.900 1.838 1.00 8.57 ? 485 ASP A C 1 ATOM 3876 O O . ASP A 1 485 ? 46.128 75.687 1.502 1.00 8.40 ? 485 ASP A O 1 ATOM 3877 C CB . ASP A 1 485 ? 44.358 76.503 4.223 1.00 9.21 ? 485 ASP A CB 1 ATOM 3878 C CG . ASP A 1 485 ? 45.593 75.869 4.832 1.00 9.83 ? 485 ASP A CG 1 ATOM 3879 O OD1 . ASP A 1 485 ? 46.616 76.581 4.950 1.00 14.31 ? 485 ASP A OD1 1 ATOM 3880 O OD2 . ASP A 1 485 ? 45.583 74.713 5.208 1.00 10.13 ? 485 ASP A OD2 1 ATOM 3881 N N . TYR A 1 486 ? 43.966 75.142 1.402 1.00 7.32 ? 486 TYR A N 1 ATOM 3882 C CA . TYR A 1 486 ? 44.244 74.063 0.464 1.00 7.87 ? 486 TYR A CA 1 ATOM 3883 C C . TYR A 1 486 ? 44.828 74.610 -0.839 1.00 7.58 ? 486 TYR A C 1 ATOM 3884 O O . TYR A 1 486 ? 45.751 73.978 -1.377 1.00 8.38 ? 486 TYR A O 1 ATOM 3885 C CB . TYR A 1 486 ? 42.974 73.281 0.103 1.00 8.10 ? 486 TYR A CB 1 ATOM 3886 C CG . TYR A 1 486 ? 42.365 72.445 1.234 1.00 7.76 ? 486 TYR A CG 1 ATOM 3887 C CD1 . TYR A 1 486 ? 43.156 71.590 2.015 1.00 9.15 ? 486 TYR A CD1 1 ATOM 3888 C CD2 . TYR A 1 486 ? 40.992 72.491 1.425 1.00 8.47 ? 486 TYR A CD2 1 ATOM 3889 C CE1 . TYR A 1 486 ? 42.536 70.746 3.016 1.00 9.56 ? 486 TYR A CE1 1 ATOM 3890 C CE2 . TYR A 1 486 ? 40.365 71.667 2.387 1.00 8.01 ? 486 TYR A CE2 1 ATOM 3891 C CZ . TYR A 1 486 ? 41.151 70.822 3.152 1.00 8.76 ? 486 TYR A CZ 1 ATOM 3892 O OH . TYR A 1 486 ? 40.527 69.999 4.087 1.00 10.09 ? 486 TYR A OH 1 ATOM 3893 N N . GLU A 1 487 ? 44.297 75.723 -1.343 1.00 8.56 ? 487 GLU A N 1 ATOM 3894 C CA . GLU A 1 487 ? 44.813 76.305 -2.574 1.00 8.49 ? 487 GLU A CA 1 ATOM 3895 C C . GLU A 1 487 ? 46.266 76.746 -2.402 1.00 8.70 ? 487 GLU A C 1 ATOM 3896 O O . GLU A 1 487 ? 47.120 76.466 -3.274 1.00 9.28 ? 487 GLU A O 1 ATOM 3897 C CB . GLU A 1 487 ? 43.961 77.499 -2.971 1.00 9.17 ? 487 GLU A CB 1 ATOM 3898 C CG . GLU A 1 487 ? 44.409 78.073 -4.317 1.00 12.04 ? 487 GLU A CG 1 ATOM 3899 C CD . GLU A 1 487 ? 43.548 79.186 -4.820 1.00 15.04 ? 487 GLU A CD 1 ATOM 3900 O OE1 . GLU A 1 487 ? 42.395 79.362 -4.406 1.00 16.58 ? 487 GLU A OE1 1 ATOM 3901 O OE2 . GLU A 1 487 ? 44.090 79.907 -5.691 1.00 19.56 ? 487 GLU A OE2 1 ATOM 3902 N N . GLN A 1 488 ? 46.565 77.392 -1.279 1.00 9.43 ? 488 GLN A N 1 ATOM 3903 C CA . GLN A 1 488 ? 47.951 77.838 -1.027 1.00 10.31 ? 488 GLN A CA 1 ATOM 3904 C C . GLN A 1 488 ? 48.875 76.655 -0.946 1.00 9.13 ? 488 GLN A C 1 ATOM 3905 O O . GLN A 1 488 ? 49.998 76.683 -1.509 1.00 9.33 ? 488 GLN A O 1 ATOM 3906 C CB . GLN A 1 488 ? 48.022 78.578 0.331 1.00 13.32 ? 488 GLN A CB 1 ATOM 3907 C CG . GLN A 1 488 ? 47.349 79.907 0.244 1.00 18.57 ? 488 GLN A CG 1 ATOM 3908 C CD . GLN A 1 488 ? 47.356 80.639 1.580 1.00 21.84 ? 488 GLN A CD 1 ATOM 3909 O OE1 . GLN A 1 488 ? 47.095 81.824 1.615 1.00 25.95 ? 488 GLN A OE1 1 ATOM 3910 N NE2 . GLN A 1 488 ? 47.628 79.930 2.680 1.00 22.99 ? 488 GLN A NE2 1 ATOM 3911 N N . ARG A 1 489 ? 48.484 75.583 -0.254 1.00 8.52 ? 489 ARG A N 1 ATOM 3912 C CA . ARG A 1 489 ? 49.303 74.384 -0.169 1.00 8.22 ? 489 ARG A CA 1 ATOM 3913 C C . ARG A 1 489 ? 49.517 73.793 -1.561 1.00 8.25 ? 489 ARG A C 1 ATOM 3914 O O . ARG A 1 489 ? 50.636 73.384 -1.900 1.00 8.10 ? 489 ARG A O 1 ATOM 3915 C CB . ARG A 1 489 ? 48.624 73.372 0.765 1.00 8.20 ? 489 ARG A CB 1 ATOM 3916 C CG . ARG A 1 489 ? 48.674 73.763 2.184 1.00 9.13 ? 489 ARG A CG 1 ATOM 3917 C CD . ARG A 1 489 ? 47.730 72.790 2.953 1.00 10.49 ? 489 ARG A CD 1 ATOM 3918 N NE . ARG A 1 489 ? 47.828 72.935 4.431 1.00 9.66 ? 489 ARG A NE 1 ATOM 3919 C CZ . ARG A 1 489 ? 48.666 72.285 5.220 1.00 10.74 ? 489 ARG A CZ 1 ATOM 3920 N NH1 . ARG A 1 489 ? 49.516 71.399 4.734 1.00 12.09 ? 489 ARG A NH1 1 ATOM 3921 N NH2 . ARG A 1 489 ? 48.663 72.554 6.540 1.00 12.52 ? 489 ARG A NH2 1 ATOM 3922 N N . MET A 1 490 ? 48.469 73.754 -2.389 1.00 7.38 ? 490 MET A N 1 ATOM 3923 C CA . MET A 1 490 ? 48.650 73.189 -3.727 1.00 7.45 ? 490 MET A CA 1 ATOM 3924 C C . MET A 1 490 ? 49.516 74.067 -4.606 1.00 7.54 ? 490 MET A C 1 ATOM 3925 O O . MET A 1 490 ? 50.195 73.532 -5.472 1.00 7.94 ? 490 MET A O 1 ATOM 3926 C CB . MET A 1 490 ? 47.308 72.912 -4.433 1.00 7.77 ? 490 MET A CB 1 ATOM 3927 C CG . MET A 1 490 ? 46.578 71.677 -3.784 1.00 9.12 ? 490 MET A CG 1 ATOM 3928 S SD . MET A 1 490 ? 45.228 70.986 -4.831 1.00 10.47 ? 490 MET A SD 1 ATOM 3929 C CE . MET A 1 490 ? 43.950 72.222 -4.474 1.00 12.09 ? 490 MET A CE 1 ATOM 3930 N N . GLN A 1 491 ? 49.445 75.390 -4.412 1.00 8.13 ? 491 GLN A N 1 ATOM 3931 C CA . GLN A 1 491 ? 50.314 76.283 -5.191 1.00 9.60 ? 491 GLN A CA 1 ATOM 3932 C C . GLN A 1 491 ? 51.763 76.026 -4.838 1.00 9.66 ? 491 GLN A C 1 ATOM 3933 O O . GLN A 1 491 ? 52.632 75.964 -5.737 1.00 10.48 ? 491 GLN A O 1 ATOM 3934 C CB . GLN A 1 491 ? 49.981 77.753 -4.919 1.00 11.02 ? 491 GLN A CB 1 ATOM 3935 C CG . GLN A 1 491 ? 50.832 78.611 -5.848 1.00 17.72 ? 491 GLN A CG 1 ATOM 3936 C CD . GLN A 1 491 ? 50.680 78.199 -7.306 1.00 21.61 ? 491 GLN A CD 1 ATOM 3937 O OE1 . GLN A 1 491 ? 51.671 78.014 -8.041 1.00 24.71 ? 491 GLN A OE1 1 ATOM 3938 N NE2 . GLN A 1 491 ? 49.452 78.036 -7.723 1.00 23.17 ? 491 GLN A NE2 1 ATOM 3939 N N . GLU A 1 492 ? 52.051 75.818 -3.558 1.00 9.75 ? 492 GLU A N 1 ATOM 3940 C CA . GLU A 1 492 ? 53.423 75.503 -3.155 1.00 10.51 ? 492 GLU A CA 1 ATOM 3941 C C . GLU A 1 492 ? 53.826 74.161 -3.752 1.00 9.82 ? 492 GLU A C 1 ATOM 3942 O O . GLU A 1 492 ? 54.969 73.998 -4.248 1.00 10.19 ? 492 GLU A O 1 ATOM 3943 C CB . GLU A 1 492 ? 53.546 75.490 -1.630 1.00 12.86 ? 492 GLU A CB 1 ATOM 3944 C CG . GLU A 1 492 ? 53.500 76.877 -1.009 1.00 20.08 ? 492 GLU A CG 1 ATOM 3945 C CD . GLU A 1 492 ? 54.398 77.859 -1.743 1.00 23.63 ? 492 GLU A CD 1 ATOM 3946 O OE1 . GLU A 1 492 ? 55.620 77.565 -1.886 1.00 28.07 ? 492 GLU A OE1 1 ATOM 3947 O OE2 . GLU A 1 492 ? 53.881 78.908 -2.199 1.00 27.84 ? 492 GLU A OE2 1 ATOM 3948 N N . ALA A 1 493 ? 52.912 73.187 -3.788 1.00 9.05 ? 493 ALA A N 1 ATOM 3949 C CA . ALA A 1 493 ? 53.245 71.889 -4.375 1.00 7.21 ? 493 ALA A CA 1 ATOM 3950 C C . ALA A 1 493 ? 53.538 72.030 -5.887 1.00 8.00 ? 493 ALA A C 1 ATOM 3951 O O . ALA A 1 493 ? 54.422 71.318 -6.392 1.00 7.05 ? 493 ALA A O 1 ATOM 3952 C CB . ALA A 1 493 ? 52.077 70.902 -4.171 1.00 8.23 ? 493 ALA A CB 1 ATOM 3953 N N . LEU A 1 494 ? 52.756 72.850 -6.614 1.00 7.41 ? 494 LEU A N 1 ATOM 3954 C CA . LEU A 1 494 ? 53.034 73.041 -8.045 1.00 7.66 ? 494 LEU A CA 1 ATOM 3955 C C . LEU A 1 494 ? 54.437 73.651 -8.228 1.00 7.67 ? 494 LEU A C 1 ATOM 3956 O O . LEU A 1 494 ? 55.156 73.212 -9.145 1.00 8.37 ? 494 LEU A O 1 ATOM 3957 C CB . LEU A 1 494 ? 51.943 73.967 -8.637 1.00 8.71 ? 494 LEU A CB 1 ATOM 3958 C CG . LEU A 1 494 ? 50.575 73.292 -8.892 1.00 8.73 ? 494 LEU A CG 1 ATOM 3959 C CD1 . LEU A 1 494 ? 49.554 74.377 -9.210 1.00 10.57 ? 494 LEU A CD1 1 ATOM 3960 C CD2 . LEU A 1 494 ? 50.662 72.267 -9.997 1.00 9.15 ? 494 LEU A CD2 1 ATOM 3961 N N . LYS A 1 495 ? 54.820 74.613 -7.385 1.00 9.26 ? 495 LYS A N 1 ATOM 3962 C CA . LYS A 1 495 ? 56.184 75.210 -7.496 1.00 9.15 ? 495 LYS A CA 1 ATOM 3963 C C . LYS A 1 495 ? 57.238 74.161 -7.178 1.00 8.55 ? 495 LYS A C 1 ATOM 3964 O O . LYS A 1 495 ? 58.268 74.099 -7.877 1.00 9.36 ? 495 LYS A O 1 ATOM 3965 C CB . LYS A 1 495 ? 56.288 76.390 -6.571 1.00 11.42 ? 495 LYS A CB 1 ATOM 3966 C CG . LYS A 1 495 ? 55.410 77.544 -7.020 1.00 16.35 ? 495 LYS A CG 1 ATOM 3967 C CD . LYS A 1 495 ? 55.555 78.807 -6.150 1.00 21.55 ? 495 LYS A CD 1 ATOM 3968 C CE . LYS A 1 495 ? 55.092 78.605 -4.727 1.00 24.74 ? 495 LYS A CE 1 ATOM 3969 N NZ . LYS A 1 495 ? 55.197 79.908 -3.920 1.00 27.61 ? 495 LYS A NZ 1 ATOM 3970 N N . ALA A 1 496 ? 57.000 73.280 -6.209 1.00 7.88 ? 496 ALA A N 1 ATOM 3971 C CA . ALA A 1 496 ? 57.928 72.225 -5.921 1.00 7.82 ? 496 ALA A CA 1 ATOM 3972 C C . ALA A 1 496 ? 58.104 71.285 -7.124 1.00 7.48 ? 496 ALA A C 1 ATOM 3973 O O . ALA A 1 496 ? 59.216 70.856 -7.494 1.00 8.12 ? 496 ALA A O 1 ATOM 3974 C CB . ALA A 1 496 ? 57.440 71.429 -4.664 1.00 8.44 ? 496 ALA A CB 1 ATOM 3975 N N . CYS A 1 497 ? 56.985 70.912 -7.751 1.00 7.27 ? 497 CYS A N 1 ATOM 3976 C CA . CYS A 1 497 ? 57.045 70.049 -8.939 1.00 7.73 ? 497 CYS A CA 1 ATOM 3977 C C . CYS A 1 497 ? 57.804 70.723 -10.059 1.00 8.00 ? 497 CYS A C 1 ATOM 3978 O O . CYS A 1 497 ? 58.627 70.084 -10.723 1.00 7.55 ? 497 CYS A O 1 ATOM 3979 C CB . CYS A 1 497 ? 55.617 69.738 -9.435 1.00 7.62 ? 497 CYS A CB 1 ATOM 3980 S SG . CYS A 1 497 ? 54.717 68.544 -8.347 1.00 8.20 ? 497 CYS A SG 1 ATOM 3981 N N . GLN A 1 498 ? 57.512 71.988 -10.308 1.00 7.33 ? 498 GLN A N 1 ATOM 3982 C CA . GLN A 1 498 ? 58.232 72.695 -11.394 1.00 8.41 ? 498 GLN A CA 1 ATOM 3983 C C . GLN A 1 498 ? 59.726 72.680 -11.114 1.00 8.18 ? 498 GLN A C 1 ATOM 3984 O O . GLN A 1 498 ? 60.523 72.406 -12.010 1.00 8.52 ? 498 GLN A O 1 ATOM 3985 C CB . GLN A 1 498 ? 57.753 74.147 -11.504 1.00 8.01 ? 498 GLN A CB 1 ATOM 3986 C CG A GLN A 1 498 ? 58.631 74.989 -12.446 0.50 9.86 ? 498 GLN A CG 1 ATOM 3987 C CG B GLN A 1 498 ? 56.210 74.283 -11.881 0.50 13.57 ? 498 GLN A CG 1 ATOM 3988 C CD A GLN A 1 498 ? 58.173 76.446 -12.554 0.50 10.70 ? 498 GLN A CD 1 ATOM 3989 C CD B GLN A 1 498 ? 55.671 75.705 -11.787 0.50 16.00 ? 498 GLN A CD 1 ATOM 3990 O OE1 A GLN A 1 498 ? 58.040 77.152 -11.541 0.50 14.21 ? 498 GLN A OE1 1 ATOM 3991 O OE1 B GLN A 1 498 ? 56.163 76.607 -12.466 0.50 18.93 ? 498 GLN A OE1 1 ATOM 3992 N NE2 A GLN A 1 498 ? 57.963 76.909 -13.773 0.50 7.49 ? 498 GLN A NE2 1 ATOM 3993 N NE2 B GLN A 1 498 ? 54.674 75.915 -10.928 0.50 18.11 ? 498 GLN A NE2 1 ATOM 3994 N N . MET A 1 499 ? 60.134 72.981 -9.883 1.00 7.86 ? 499 MET A N 1 ATOM 3995 C CA . MET A 1 499 ? 61.559 72.988 -9.569 1.00 8.57 ? 499 MET A CA 1 ATOM 3996 C C . MET A 1 499 ? 62.204 71.633 -9.863 1.00 8.15 ? 499 MET A C 1 ATOM 3997 O O . MET A 1 499 ? 63.226 71.545 -10.545 1.00 8.70 ? 499 MET A O 1 ATOM 3998 C CB . MET A 1 499 ? 61.716 73.383 -8.100 1.00 8.60 ? 499 MET A CB 1 ATOM 3999 C CG . MET A 1 499 ? 63.136 73.258 -7.571 1.00 10.62 ? 499 MET A CG 1 ATOM 4000 S SD . MET A 1 499 ? 64.457 74.197 -8.381 1.00 14.38 ? 499 MET A SD 1 ATOM 4001 C CE . MET A 1 499 ? 63.964 75.857 -7.931 1.00 16.40 ? 499 MET A CE 1 ATOM 4002 N N . VAL A 1 500 ? 61.568 70.546 -9.418 1.00 7.56 ? 500 VAL A N 1 ATOM 4003 C CA . VAL A 1 500 ? 62.125 69.220 -9.645 1.00 7.44 ? 500 VAL A CA 1 ATOM 4004 C C . VAL A 1 500 ? 62.141 68.907 -11.129 1.00 7.29 ? 500 VAL A C 1 ATOM 4005 O O . VAL A 1 500 ? 63.144 68.374 -11.638 1.00 7.99 ? 500 VAL A O 1 ATOM 4006 C CB . VAL A 1 500 ? 61.330 68.159 -8.832 1.00 7.82 ? 500 VAL A CB 1 ATOM 4007 C CG1 . VAL A 1 500 ? 61.729 66.773 -9.233 1.00 8.95 ? 500 VAL A CG1 1 ATOM 4008 C CG2 . VAL A 1 500 ? 61.605 68.424 -7.304 1.00 9.40 ? 500 VAL A CG2 1 ATOM 4009 N N . MET A 1 501 ? 61.030 69.181 -11.815 1.00 7.05 ? 501 MET A N 1 ATOM 4010 C CA . MET A 1 501 ? 60.975 68.911 -13.238 1.00 7.38 ? 501 MET A CA 1 ATOM 4011 C C . MET A 1 501 ? 62.059 69.630 -14.007 1.00 6.69 ? 501 MET A C 1 ATOM 4012 O O . MET A 1 501 ? 62.738 68.977 -14.851 1.00 7.88 ? 501 MET A O 1 ATOM 4013 C CB . MET A 1 501 ? 59.600 69.289 -13.817 1.00 7.82 ? 501 MET A CB 1 ATOM 4014 C CG . MET A 1 501 ? 58.483 68.292 -13.355 1.00 7.98 ? 501 MET A CG 1 ATOM 4015 S SD . MET A 1 501 ? 56.822 68.999 -13.596 1.00 11.94 ? 501 MET A SD 1 ATOM 4016 C CE . MET A 1 501 ? 56.695 68.787 -15.347 1.00 12.66 ? 501 MET A CE 1 ATOM 4017 N N . GLN A 1 502 ? 62.219 70.931 -13.777 1.00 7.94 ? 502 GLN A N 1 ATOM 4018 C CA . GLN A 1 502 ? 63.187 71.666 -14.618 1.00 7.60 ? 502 GLN A CA 1 ATOM 4019 C C . GLN A 1 502 ? 64.624 71.285 -14.286 1.00 8.48 ? 502 GLN A C 1 ATOM 4020 O O . GLN A 1 502 ? 65.450 71.206 -15.209 1.00 8.89 ? 502 GLN A O 1 ATOM 4021 C CB . GLN A 1 502 ? 62.913 73.149 -14.522 1.00 8.43 ? 502 GLN A CB 1 ATOM 4022 C CG . GLN A 1 502 ? 63.105 73.763 -13.138 1.00 9.36 ? 502 GLN A CG 1 ATOM 4023 C CD . GLN A 1 502 ? 64.527 74.299 -12.928 1.00 10.49 ? 502 GLN A CD 1 ATOM 4024 O OE1 . GLN A 1 502 ? 65.286 74.462 -13.897 1.00 11.62 ? 502 GLN A OE1 1 ATOM 4025 N NE2 . GLN A 1 502 ? 64.876 74.632 -11.691 1.00 11.47 ? 502 GLN A NE2 1 ATOM 4026 N N . GLN A 1 503 ? 64.909 71.004 -13.026 1.00 7.88 ? 503 GLN A N 1 ATOM 4027 C CA . GLN A 1 503 ? 66.290 70.509 -12.727 1.00 8.30 ? 503 GLN A CA 1 ATOM 4028 C C . GLN A 1 503 ? 66.500 69.171 -13.431 1.00 8.87 ? 503 GLN A C 1 ATOM 4029 O O . GLN A 1 503 ? 67.614 68.869 -13.945 1.00 8.68 ? 503 GLN A O 1 ATOM 4030 C CB . GLN A 1 503 ? 66.508 70.258 -11.226 1.00 9.65 ? 503 GLN A CB 1 ATOM 4031 C CG . GLN A 1 503 ? 66.614 71.532 -10.388 1.00 10.44 ? 503 GLN A CG 1 ATOM 4032 C CD . GLN A 1 503 ? 67.963 72.255 -10.545 1.00 11.46 ? 503 GLN A CD 1 ATOM 4033 O OE1 . GLN A 1 503 ? 68.958 71.605 -10.838 1.00 14.40 ? 503 GLN A OE1 1 ATOM 4034 N NE2 . GLN A 1 503 ? 67.993 73.570 -10.312 1.00 13.06 ? 503 GLN A NE2 1 ATOM 4035 N N . SER A 1 504 ? 65.477 68.292 -13.485 1.00 7.68 ? 504 SER A N 1 ATOM 4036 C CA . SER A 1 504 ? 65.618 66.993 -14.133 1.00 8.75 ? 504 SER A CA 1 ATOM 4037 C C . SER A 1 504 ? 65.861 67.149 -15.637 1.00 8.79 ? 504 SER A C 1 ATOM 4038 O O . SER A 1 504 ? 66.733 66.474 -16.214 1.00 8.82 ? 504 SER A O 1 ATOM 4039 C CB . SER A 1 504 ? 64.346 66.138 -13.900 1.00 8.46 ? 504 SER A CB 1 ATOM 4040 O OG . SER A 1 504 ? 64.256 65.852 -12.488 1.00 9.71 ? 504 SER A OG 1 ATOM 4041 N N . VAL A 1 505 ? 65.090 68.029 -16.280 1.00 8.25 ? 505 VAL A N 1 ATOM 4042 C CA . VAL A 1 505 ? 65.256 68.231 -17.732 1.00 8.46 ? 505 VAL A CA 1 ATOM 4043 C C . VAL A 1 505 ? 66.699 68.762 -18.038 1.00 8.40 ? 505 VAL A C 1 ATOM 4044 O O . VAL A 1 505 ? 67.372 68.279 -18.974 1.00 10.08 ? 505 VAL A O 1 ATOM 4045 C CB . VAL A 1 505 ? 64.183 69.236 -18.238 1.00 8.95 ? 505 VAL A CB 1 ATOM 4046 C CG1 . VAL A 1 505 ? 64.511 69.712 -19.674 1.00 10.21 ? 505 VAL A CG1 1 ATOM 4047 C CG2 . VAL A 1 505 ? 62.771 68.576 -18.201 1.00 10.62 ? 505 VAL A CG2 1 ATOM 4048 N N . TYR A 1 506 ? 67.199 69.654 -17.203 1.00 8.70 ? 506 TYR A N 1 ATOM 4049 C CA . TYR A 1 506 ? 68.532 70.197 -17.456 1.00 9.48 ? 506 TYR A CA 1 ATOM 4050 C C . TYR A 1 506 ? 69.560 69.069 -17.361 1.00 10.13 ? 506 TYR A C 1 ATOM 4051 O O . TYR A 1 506 ? 70.477 68.949 -18.186 1.00 10.93 ? 506 TYR A O 1 ATOM 4052 C CB . TYR A 1 506 ? 68.830 71.317 -16.458 1.00 10.60 ? 506 TYR A CB 1 ATOM 4053 C CG . TYR A 1 506 ? 70.113 72.023 -16.721 1.00 13.58 ? 506 TYR A CG 1 ATOM 4054 C CD1 . TYR A 1 506 ? 70.275 72.673 -17.960 1.00 15.37 ? 506 TYR A CD1 1 ATOM 4055 C CD2 . TYR A 1 506 ? 71.128 72.018 -15.795 1.00 13.82 ? 506 TYR A CD2 1 ATOM 4056 C CE1 . TYR A 1 506 ? 71.424 73.312 -18.278 1.00 17.59 ? 506 TYR A CE1 1 ATOM 4057 C CE2 . TYR A 1 506 ? 72.383 72.673 -16.125 1.00 16.96 ? 506 TYR A CE2 1 ATOM 4058 C CZ . TYR A 1 506 ? 72.460 73.308 -17.386 1.00 16.15 ? 506 TYR A CZ 1 ATOM 4059 O OH . TYR A 1 506 ? 73.548 74.069 -17.793 1.00 18.21 ? 506 TYR A OH 1 ATOM 4060 N N . ARG A 1 507 ? 69.401 68.200 -16.372 1.00 9.39 ? 507 ARG A N 1 ATOM 4061 C CA . ARG A 1 507 ? 70.335 67.089 -16.231 1.00 9.22 ? 507 ARG A CA 1 ATOM 4062 C C . ARG A 1 507 ? 70.215 66.058 -17.351 1.00 10.44 ? 507 ARG A C 1 ATOM 4063 O O . ARG A 1 507 ? 71.210 65.524 -17.862 1.00 10.40 ? 507 ARG A O 1 ATOM 4064 C CB . ARG A 1 507 ? 70.116 66.442 -14.882 1.00 10.19 ? 507 ARG A CB 1 ATOM 4065 C CG . ARG A 1 507 ? 71.209 65.382 -14.568 1.00 11.30 ? 507 ARG A CG 1 ATOM 4066 C CD . ARG A 1 507 ? 71.063 64.932 -13.093 1.00 12.98 ? 507 ARG A CD 1 ATOM 4067 N NE . ARG A 1 507 ? 72.115 63.958 -12.702 1.00 15.08 ? 507 ARG A NE 1 ATOM 4068 C CZ . ARG A 1 507 ? 72.135 63.353 -11.506 1.00 14.54 ? 507 ARG A CZ 1 ATOM 4069 N NH1 . ARG A 1 507 ? 71.214 63.620 -10.591 1.00 15.71 ? 507 ARG A NH1 1 ATOM 4070 N NH2 . ARG A 1 507 ? 73.031 62.405 -11.260 1.00 17.41 ? 507 ARG A NH2 1 ATOM 4071 N N . LEU A 1 508 ? 68.990 65.752 -17.764 1.00 8.82 ? 508 LEU A N 1 ATOM 4072 C CA . LEU A 1 508 ? 68.796 64.770 -18.782 1.00 8.65 ? 508 LEU A CA 1 ATOM 4073 C C . LEU A 1 508 ? 69.225 65.181 -20.194 1.00 9.52 ? 508 LEU A C 1 ATOM 4074 O O . LEU A 1 508 ? 69.429 64.307 -21.068 1.00 11.14 ? 508 LEU A O 1 ATOM 4075 C CB . LEU A 1 508 ? 67.305 64.367 -18.846 1.00 8.71 ? 508 LEU A CB 1 ATOM 4076 C CG . LEU A 1 508 ? 66.852 63.561 -17.615 1.00 9.06 ? 508 LEU A CG 1 ATOM 4077 C CD1 . LEU A 1 508 ? 65.290 63.632 -17.543 1.00 10.43 ? 508 LEU A CD1 1 ATOM 4078 C CD2 . LEU A 1 508 ? 67.312 62.115 -17.750 1.00 11.88 ? 508 LEU A CD2 1 ATOM 4079 N N . LEU A 1 509 ? 69.271 66.498 -20.429 1.00 9.86 ? 509 LEU A N 1 ATOM 4080 C CA . LEU A 1 509 ? 69.562 67.004 -21.779 1.00 10.01 ? 509 LEU A CA 1 ATOM 4081 C C . LEU A 1 509 ? 70.835 67.843 -21.859 1.00 11.05 ? 509 LEU A C 1 ATOM 4082 O O . LEU A 1 509 ? 70.979 68.617 -22.799 1.00 12.23 ? 509 LEU A O 1 ATOM 4083 C CB . LEU A 1 509 ? 68.334 67.790 -22.298 1.00 9.49 ? 509 LEU A CB 1 ATOM 4084 C CG . LEU A 1 509 ? 67.135 66.895 -22.636 1.00 9.75 ? 509 LEU A CG 1 ATOM 4085 C CD1 . LEU A 1 509 ? 66.021 67.873 -23.063 1.00 9.64 ? 509 LEU A CD1 1 ATOM 4086 C CD2 . LEU A 1 509 ? 67.389 65.881 -23.753 1.00 11.04 ? 509 LEU A CD2 1 ATOM 4087 N N . THR A 1 510 ? 71.748 67.726 -20.902 1.00 10.21 ? 510 THR A N 1 ATOM 4088 C CA . THR A 1 510 ? 73.005 68.476 -20.985 1.00 11.42 ? 510 THR A CA 1 ATOM 4089 C C . THR A 1 510 ? 74.155 67.468 -21.015 1.00 12.00 ? 510 THR A C 1 ATOM 4090 O O . THR A 1 510 ? 74.149 66.491 -20.271 1.00 11.59 ? 510 THR A O 1 ATOM 4091 C CB . THR A 1 510 ? 73.155 69.408 -19.800 1.00 9.89 ? 510 THR A CB 1 ATOM 4092 O OG1 . THR A 1 510 ? 72.054 70.343 -19.832 1.00 11.56 ? 510 THR A OG1 1 ATOM 4093 C CG2 . THR A 1 510 ? 74.474 70.263 -19.862 1.00 10.94 ? 510 THR A CG2 1 ATOM 4094 N N . LYS A 1 511 ? 75.119 67.716 -21.907 1.00 13.37 ? 511 LYS A N 1 ATOM 4095 C CA . LYS A 1 511 ? 76.280 66.831 -21.988 1.00 14.08 ? 511 LYS A CA 1 ATOM 4096 C C . LYS A 1 511 ? 76.796 66.639 -20.583 1.00 13.54 ? 511 LYS A C 1 ATOM 4097 O O . LYS A 1 511 ? 77.076 67.578 -19.829 1.00 12.73 ? 511 LYS A O 1 ATOM 4098 C CB . LYS A 1 511 ? 77.336 67.504 -22.852 1.00 15.71 ? 511 LYS A CB 1 ATOM 4099 C CG . LYS A 1 511 ? 78.542 66.618 -22.988 1.00 19.93 ? 511 LYS A CG 1 ATOM 4100 C CD . LYS A 1 511 ? 79.512 67.131 -24.016 1.00 23.86 ? 511 LYS A CD 1 ATOM 4101 C CE . LYS A 1 511 ? 80.601 66.072 -24.195 1.00 26.22 ? 511 LYS A CE 1 ATOM 4102 N NZ . LYS A 1 511 ? 81.629 66.477 -25.186 1.00 29.38 ? 511 LYS A NZ 1 ATOM 4103 N N . PRO A 1 512 ? 77.012 65.381 -20.195 1.00 15.22 ? 512 PRO A N 1 ATOM 4104 C CA . PRO A 1 512 ? 77.476 65.114 -18.847 1.00 15.79 ? 512 PRO A CA 1 ATOM 4105 C C . PRO A 1 512 ? 78.717 65.838 -18.323 1.00 15.01 ? 512 PRO A C 1 ATOM 4106 O O . PRO A 1 512 ? 78.748 66.305 -17.175 1.00 15.13 ? 512 PRO A O 1 ATOM 4107 C CB . PRO A 1 512 ? 77.652 63.589 -18.844 1.00 17.86 ? 512 PRO A CB 1 ATOM 4108 C CG . PRO A 1 512 ? 76.659 63.139 -19.834 1.00 18.86 ? 512 PRO A CG 1 ATOM 4109 C CD . PRO A 1 512 ? 76.737 64.137 -20.940 1.00 16.99 ? 512 PRO A CD 1 ATOM 4110 N N . SER A 1 513 ? 79.729 65.959 -19.177 1.00 14.60 ? 513 SER A N 1 ATOM 4111 C CA . SER A 1 513 ? 80.936 66.616 -18.689 1.00 14.92 ? 513 SER A CA 1 ATOM 4112 C C . SER A 1 513 ? 80.842 68.125 -18.645 1.00 14.28 ? 513 SER A C 1 ATOM 4113 O O . SER A 1 513 ? 81.798 68.803 -18.220 1.00 15.20 ? 513 SER A O 1 ATOM 4114 C CB . SER A 1 513 ? 82.106 66.218 -19.553 1.00 15.65 ? 513 SER A CB 1 ATOM 4115 O OG . SER A 1 513 ? 81.869 66.552 -20.882 1.00 16.19 ? 513 SER A OG 1 ATOM 4116 N N . ILE A 1 514 ? 79.693 68.679 -19.031 1.00 14.35 ? 514 ILE A N 1 ATOM 4117 C CA . ILE A 1 514 ? 79.459 70.121 -19.011 1.00 15.10 ? 514 ILE A CA 1 ATOM 4118 C C . ILE A 1 514 ? 78.451 70.463 -17.882 1.00 13.71 ? 514 ILE A C 1 ATOM 4119 O O . ILE A 1 514 ? 78.463 71.550 -17.315 1.00 13.18 ? 514 ILE A O 1 ATOM 4120 C CB . ILE A 1 514 ? 78.841 70.594 -20.398 1.00 16.69 ? 514 ILE A CB 1 ATOM 4121 C CG1 . ILE A 1 514 ? 79.913 70.508 -21.493 1.00 18.06 ? 514 ILE A CG1 1 ATOM 4122 C CG2 . ILE A 1 514 ? 78.180 71.993 -20.256 1.00 17.28 ? 514 ILE A CG2 1 ATOM 4123 C CD1 . ILE A 1 514 ? 79.434 70.841 -22.838 1.00 20.60 ? 514 ILE A CD1 1 ATOM 4124 N N . TYR A 1 515 ? 77.590 69.496 -17.547 1.00 13.71 ? 515 TYR A N 1 ATOM 4125 C CA . TYR A 1 515 ? 76.531 69.728 -16.547 1.00 12.72 ? 515 TYR A CA 1 ATOM 4126 C C . TYR A 1 515 ? 77.080 70.300 -15.250 1.00 12.41 ? 515 TYR A C 1 ATOM 4127 O O . TYR A 1 515 ? 77.947 69.659 -14.612 1.00 12.79 ? 515 TYR A O 1 ATOM 4128 C CB . TYR A 1 515 ? 75.796 68.388 -16.361 1.00 12.79 ? 515 TYR A CB 1 ATOM 4129 C CG . TYR A 1 515 ? 74.784 68.401 -15.271 1.00 11.92 ? 515 TYR A CG 1 ATOM 4130 C CD1 . TYR A 1 515 ? 73.612 69.155 -15.372 1.00 11.39 ? 515 TYR A CD1 1 ATOM 4131 C CD2 . TYR A 1 515 ? 74.976 67.586 -14.168 1.00 12.50 ? 515 TYR A CD2 1 ATOM 4132 C CE1 . TYR A 1 515 ? 72.639 69.076 -14.379 1.00 11.64 ? 515 TYR A CE1 1 ATOM 4133 C CE2 . TYR A 1 515 ? 74.013 67.491 -13.171 1.00 11.93 ? 515 TYR A CE2 1 ATOM 4134 C CZ . TYR A 1 515 ? 72.844 68.241 -13.289 1.00 12.28 ? 515 TYR A CZ 1 ATOM 4135 O OH . TYR A 1 515 ? 71.906 68.126 -12.313 1.00 12.68 ? 515 TYR A OH 1 ATOM 4136 N N . SER A 1 516 ? 76.606 71.474 -14.807 1.00 12.91 ? 516 SER A N 1 ATOM 4137 C CA . SER A 1 516 ? 77.140 72.126 -13.577 1.00 13.06 ? 516 SER A CA 1 ATOM 4138 C C . SER A 1 516 ? 75.949 72.777 -12.880 1.00 13.52 ? 516 SER A C 1 ATOM 4139 O O . SER A 1 516 ? 75.752 73.997 -12.923 1.00 14.47 ? 516 SER A O 1 ATOM 4140 C CB . SER A 1 516 ? 78.144 73.192 -14.042 1.00 14.90 ? 516 SER A CB 1 ATOM 4141 O OG . SER A 1 516 ? 78.860 73.657 -12.909 1.00 17.85 ? 516 SER A OG 1 ATOM 4142 N N . PRO A 1 517 ? 75.177 71.953 -12.196 1.00 14.23 ? 517 PRO A N 1 ATOM 4143 C CA . PRO A 1 517 ? 73.999 72.517 -11.566 1.00 14.98 ? 517 PRO A CA 1 ATOM 4144 C C . PRO A 1 517 ? 74.058 73.376 -10.358 1.00 14.52 ? 517 PRO A C 1 ATOM 4145 O O . PRO A 1 517 ? 74.832 73.115 -9.445 1.00 18.28 ? 517 PRO A O 1 ATOM 4146 C CB . PRO A 1 517 ? 73.148 71.259 -11.314 1.00 15.70 ? 517 PRO A CB 1 ATOM 4147 C CG . PRO A 1 517 ? 74.228 70.254 -10.912 1.00 14.69 ? 517 PRO A CG 1 ATOM 4148 C CD . PRO A 1 517 ? 75.279 70.499 -12.004 1.00 14.84 ? 517 PRO A CD 1 ATOM 4149 N N . ASP A 1 518 ? 73.215 74.399 -10.339 1.00 15.31 ? 518 ASP A N 1 ATOM 4150 C CA . ASP A 1 518 ? 73.005 75.218 -9.141 1.00 15.28 ? 518 ASP A CA 1 ATOM 4151 C C . ASP A 1 518 ? 71.568 74.730 -8.813 1.00 14.27 ? 518 ASP A C 1 ATOM 4152 O O . ASP A 1 518 ? 70.630 75.002 -9.568 1.00 14.60 ? 518 ASP A O 1 ATOM 4153 C CB . ASP A 1 518 ? 72.985 76.699 -9.493 1.00 17.40 ? 518 ASP A CB 1 ATOM 4154 C CG . ASP A 1 518 ? 72.463 77.566 -8.366 1.00 18.74 ? 518 ASP A CG 1 ATOM 4155 O OD1 . ASP A 1 518 ? 71.884 77.046 -7.370 1.00 18.11 ? 518 ASP A OD1 1 ATOM 4156 O OD2 . ASP A 1 518 ? 72.614 78.799 -8.520 1.00 21.59 ? 518 ASP A OD2 1 ATOM 4157 N N . PHE A 1 519 ? 71.432 74.019 -7.701 1.00 14.29 ? 519 PHE A N 1 ATOM 4158 C CA . PHE A 1 519 ? 70.144 73.415 -7.371 1.00 14.29 ? 519 PHE A CA 1 ATOM 4159 C C . PHE A 1 519 ? 69.070 74.389 -6.970 1.00 15.30 ? 519 PHE A C 1 ATOM 4160 O O . PHE A 1 519 ? 67.910 73.985 -6.820 1.00 16.77 ? 519 PHE A O 1 ATOM 4161 C CB . PHE A 1 519 ? 70.343 72.334 -6.327 1.00 13.86 ? 519 PHE A CB 1 ATOM 4162 C CG . PHE A 1 519 ? 71.225 71.196 -6.796 1.00 15.08 ? 519 PHE A CG 1 ATOM 4163 C CD1 . PHE A 1 519 ? 70.944 70.481 -7.983 1.00 14.56 ? 519 PHE A CD1 1 ATOM 4164 C CD2 . PHE A 1 519 ? 72.316 70.808 -6.023 1.00 15.78 ? 519 PHE A CD2 1 ATOM 4165 C CE1 . PHE A 1 519 ? 71.727 69.402 -8.395 1.00 14.27 ? 519 PHE A CE1 1 ATOM 4166 C CE2 . PHE A 1 519 ? 73.104 69.733 -6.423 1.00 15.53 ? 519 PHE A CE2 1 ATOM 4167 C CZ . PHE A 1 519 ? 72.817 69.017 -7.616 1.00 15.43 ? 519 PHE A CZ 1 ATOM 4168 N N . SER A 1 520 ? 69.392 75.666 -6.838 1.00 15.20 ? 520 SER A N 1 ATOM 4169 C CA . SER A 1 520 ? 68.380 76.666 -6.504 1.00 16.17 ? 520 SER A CA 1 ATOM 4170 C C . SER A 1 520 ? 68.012 77.479 -7.775 1.00 15.65 ? 520 SER A C 1 ATOM 4171 O O . SER A 1 520 ? 67.106 78.328 -7.733 1.00 16.89 ? 520 SER A O 1 ATOM 4172 C CB . SER A 1 520 ? 68.943 77.643 -5.457 1.00 17.99 ? 520 SER A CB 1 ATOM 4173 O OG . SER A 1 520 ? 69.932 78.486 -6.047 1.00 21.25 ? 520 SER A OG 1 ATOM 4174 N N . PHE A 1 521 ? 68.682 77.185 -8.910 1.00 14.23 ? 521 PHE A N 1 ATOM 4175 C CA . PHE A 1 521 ? 68.472 77.984 -10.109 1.00 14.46 ? 521 PHE A CA 1 ATOM 4176 C C . PHE A 1 521 ? 67.362 77.472 -11.019 1.00 13.45 ? 521 PHE A C 1 ATOM 4177 O O . PHE A 1 521 ? 67.161 76.273 -11.086 1.00 13.74 ? 521 PHE A O 1 ATOM 4178 C CB . PHE A 1 521 ? 69.810 78.017 -10.891 1.00 15.06 ? 521 PHE A CB 1 ATOM 4179 C CG . PHE A 1 521 ? 69.814 78.981 -12.069 1.00 16.70 ? 521 PHE A CG 1 ATOM 4180 C CD1 . PHE A 1 521 ? 69.924 80.350 -11.834 1.00 18.69 ? 521 PHE A CD1 1 ATOM 4181 C CD2 . PHE A 1 521 ? 69.668 78.524 -13.398 1.00 16.96 ? 521 PHE A CD2 1 ATOM 4182 C CE1 . PHE A 1 521 ? 69.885 81.252 -12.893 1.00 19.73 ? 521 PHE A CE1 1 ATOM 4183 C CE2 . PHE A 1 521 ? 69.628 79.426 -14.455 1.00 18.61 ? 521 PHE A CE2 1 ATOM 4184 C CZ . PHE A 1 521 ? 69.736 80.786 -14.210 1.00 18.78 ? 521 PHE A CZ 1 ATOM 4185 N N . SER A 1 522 ? 66.741 78.386 -11.748 1.00 14.07 ? 522 SER A N 1 ATOM 4186 C CA . SER A 1 522 ? 65.686 78.035 -12.689 1.00 14.71 ? 522 SER A CA 1 ATOM 4187 C C . SER A 1 522 ? 66.245 77.977 -14.103 1.00 12.92 ? 522 SER A C 1 ATOM 4188 O O . SER A 1 522 ? 66.380 78.999 -14.782 1.00 14.90 ? 522 SER A O 1 ATOM 4189 C CB . SER A 1 522 ? 64.538 79.050 -12.626 1.00 18.24 ? 522 SER A CB 1 ATOM 4190 O OG . SER A 1 522 ? 63.688 78.633 -11.565 1.00 22.50 ? 522 SER A OG 1 ATOM 4191 N N . TYR A 1 523 ? 66.611 76.788 -14.537 1.00 10.20 ? 523 TYR A N 1 ATOM 4192 C CA . TYR A 1 523 ? 67.133 76.597 -15.902 1.00 9.70 ? 523 TYR A CA 1 ATOM 4193 C C . TYR A 1 523 ? 66.022 76.657 -16.918 1.00 9.89 ? 523 TYR A C 1 ATOM 4194 O O . TYR A 1 523 ? 66.250 77.037 -18.061 1.00 9.76 ? 523 TYR A O 1 ATOM 4195 C CB . TYR A 1 523 ? 67.843 75.241 -16.021 1.00 9.69 ? 523 TYR A CB 1 ATOM 4196 C CG . TYR A 1 523 ? 69.100 75.197 -15.216 1.00 11.04 ? 523 TYR A CG 1 ATOM 4197 C CD1 . TYR A 1 523 ? 70.268 75.784 -15.729 1.00 13.11 ? 523 TYR A CD1 1 ATOM 4198 C CD2 . TYR A 1 523 ? 69.134 74.634 -13.941 1.00 10.96 ? 523 TYR A CD2 1 ATOM 4199 C CE1 . TYR A 1 523 ? 71.420 75.812 -14.995 1.00 13.71 ? 523 TYR A CE1 1 ATOM 4200 C CE2 . TYR A 1 523 ? 70.295 74.675 -13.199 1.00 12.67 ? 523 TYR A CE2 1 ATOM 4201 C CZ . TYR A 1 523 ? 71.413 75.275 -13.737 1.00 13.95 ? 523 TYR A CZ 1 ATOM 4202 O OH . TYR A 1 523 ? 72.584 75.420 -12.961 1.00 15.60 ? 523 TYR A OH 1 ATOM 4203 N N . PHE A 1 524 ? 64.815 76.245 -16.518 1.00 9.79 ? 524 PHE A N 1 ATOM 4204 C CA . PHE A 1 524 ? 63.654 76.318 -17.381 1.00 8.95 ? 524 PHE A CA 1 ATOM 4205 C C . PHE A 1 524 ? 62.462 76.774 -16.571 1.00 10.61 ? 524 PHE A C 1 ATOM 4206 O O . PHE A 1 524 ? 62.398 76.577 -15.367 1.00 11.07 ? 524 PHE A O 1 ATOM 4207 C CB . PHE A 1 524 ? 63.222 74.933 -17.928 1.00 8.97 ? 524 PHE A CB 1 ATOM 4208 C CG . PHE A 1 524 ? 64.277 74.247 -18.799 1.00 8.81 ? 524 PHE A CG 1 ATOM 4209 C CD1 . PHE A 1 524 ? 65.279 73.492 -18.201 1.00 9.98 ? 524 PHE A CD1 1 ATOM 4210 C CD2 . PHE A 1 524 ? 64.274 74.374 -20.213 1.00 8.34 ? 524 PHE A CD2 1 ATOM 4211 C CE1 . PHE A 1 524 ? 66.242 72.900 -18.966 1.00 10.96 ? 524 PHE A CE1 1 ATOM 4212 C CE2 . PHE A 1 524 ? 65.239 73.784 -20.987 1.00 9.47 ? 524 PHE A CE2 1 ATOM 4213 C CZ . PHE A 1 524 ? 66.239 73.038 -20.358 1.00 10.56 ? 524 PHE A CZ 1 ATOM 4214 N N . THR A 1 525 ? 61.556 77.419 -17.263 1.00 10.96 ? 525 THR A N 1 ATOM 4215 C CA . THR A 1 525 ? 60.266 77.680 -16.644 1.00 12.95 ? 525 THR A CA 1 ATOM 4216 C C . THR A 1 525 ? 59.223 76.885 -17.387 1.00 11.83 ? 525 THR A C 1 ATOM 4217 O O . THR A 1 525 ? 59.288 76.685 -18.625 1.00 12.79 ? 525 THR A O 1 ATOM 4218 C CB . THR A 1 525 ? 59.861 79.097 -16.657 1.00 15.32 ? 525 THR A CB 1 ATOM 4219 O OG1 . THR A 1 525 ? 59.812 79.562 -17.977 1.00 17.56 ? 525 THR A OG1 1 ATOM 4220 C CG2 . THR A 1 525 ? 60.863 79.961 -15.904 1.00 19.01 ? 525 THR A CG2 1 ATOM 4221 N N . LEU A 1 526 ? 58.270 76.383 -16.639 1.00 11.50 ? 526 LEU A N 1 ATOM 4222 C CA . LEU A 1 526 ? 57.183 75.653 -17.260 1.00 12.15 ? 526 LEU A CA 1 ATOM 4223 C C . LEU A 1 526 ? 56.211 76.610 -17.931 1.00 12.46 ? 526 LEU A C 1 ATOM 4224 O O . LEU A 1 526 ? 55.986 77.732 -17.465 1.00 15.30 ? 526 LEU A O 1 ATOM 4225 C CB . LEU A 1 526 ? 56.412 74.813 -16.211 1.00 15.48 ? 526 LEU A CB 1 ATOM 4226 C CG . LEU A 1 526 ? 56.961 73.472 -15.782 1.00 16.97 ? 526 LEU A CG 1 ATOM 4227 C CD1 . LEU A 1 526 ? 56.120 72.934 -14.607 1.00 19.85 ? 526 LEU A CD1 1 ATOM 4228 C CD2 . LEU A 1 526 ? 56.884 72.502 -16.973 1.00 17.67 ? 526 LEU A CD2 1 ATOM 4229 N N . ASP A 1 527 ? 55.677 76.178 -19.046 1.00 9.93 ? 527 ASP A N 1 ATOM 4230 C CA . ASP A 1 527 ? 54.658 76.954 -19.756 1.00 11.03 ? 527 ASP A CA 1 ATOM 4231 C C . ASP A 1 527 ? 53.418 76.090 -19.780 1.00 10.98 ? 527 ASP A C 1 ATOM 4232 O O . ASP A 1 527 ? 53.464 74.988 -20.278 1.00 13.11 ? 527 ASP A O 1 ATOM 4233 C CB . ASP A 1 527 ? 55.110 77.322 -21.203 1.00 11.59 ? 527 ASP A CB 1 ATOM 4234 C CG . ASP A 1 527 ? 54.066 78.192 -21.920 1.00 13.58 ? 527 ASP A CG 1 ATOM 4235 O OD1 . ASP A 1 527 ? 53.833 79.321 -21.495 1.00 14.58 ? 527 ASP A OD1 1 ATOM 4236 O OD2 . ASP A 1 527 ? 53.475 77.710 -22.890 1.00 15.07 ? 527 ASP A OD2 1 ATOM 4237 N N . ASP A 1 528 ? 52.317 76.569 -19.215 1.00 10.40 ? 528 ASP A N 1 ATOM 4238 C CA . ASP A 1 528 ? 51.094 75.762 -19.200 1.00 10.33 ? 528 ASP A CA 1 ATOM 4239 C C . ASP A 1 528 ? 49.988 76.600 -19.811 1.00 11.02 ? 528 ASP A C 1 ATOM 4240 O O . ASP A 1 528 ? 49.664 77.672 -19.299 1.00 11.67 ? 528 ASP A O 1 ATOM 4241 C CB . ASP A 1 528 ? 50.773 75.359 -17.759 1.00 10.74 ? 528 ASP A CB 1 ATOM 4242 C CG . ASP A 1 528 ? 49.689 74.292 -17.677 1.00 12.08 ? 528 ASP A CG 1 ATOM 4243 O OD1 . ASP A 1 528 ? 48.662 74.386 -18.379 1.00 12.39 ? 528 ASP A OD1 1 ATOM 4244 O OD2 . ASP A 1 528 ? 49.899 73.322 -16.902 1.00 12.62 ? 528 ASP A OD2 1 ATOM 4245 N N . SER A 1 529 ? 49.470 76.107 -20.943 1.00 12.05 ? 529 SER A N 1 ATOM 4246 C CA . SER A 1 529 ? 48.385 76.776 -21.676 1.00 13.14 ? 529 SER A CA 1 ATOM 4247 C C . SER A 1 529 ? 46.994 76.658 -21.103 1.00 13.75 ? 529 SER A C 1 ATOM 4248 O O . SER A 1 529 ? 46.125 77.395 -21.496 1.00 15.23 ? 529 SER A O 1 ATOM 4249 C CB . SER A 1 529 ? 48.258 76.218 -23.107 1.00 17.03 ? 529 SER A CB 1 ATOM 4250 O OG . SER A 1 529 ? 49.469 76.382 -23.776 1.00 20.39 ? 529 SER A OG 1 ATOM 4251 N N . ARG A 1 530 ? 46.803 75.759 -20.146 1.00 11.42 ? 530 ARG A N 1 ATOM 4252 C CA . ARG A 1 530 ? 45.450 75.555 -19.620 1.00 11.99 ? 530 ARG A CA 1 ATOM 4253 C C . ARG A 1 530 ? 45.337 75.673 -18.137 1.00 13.11 ? 530 ARG A C 1 ATOM 4254 O O . ARG A 1 530 ? 44.313 75.245 -17.569 1.00 16.57 ? 530 ARG A O 1 ATOM 4255 C CB . ARG A 1 530 ? 44.908 74.183 -20.064 1.00 12.39 ? 530 ARG A CB 1 ATOM 4256 C CG . ARG A 1 530 ? 44.949 74.089 -21.601 1.00 14.53 ? 530 ARG A CG 1 ATOM 4257 C CD . ARG A 1 530 ? 44.304 72.841 -22.182 1.00 14.93 ? 530 ARG A CD 1 ATOM 4258 N NE . ARG A 1 530 ? 45.001 71.642 -21.718 1.00 13.80 ? 530 ARG A NE 1 ATOM 4259 C CZ . ARG A 1 530 ? 44.796 70.454 -22.267 1.00 15.30 ? 530 ARG A CZ 1 ATOM 4260 N NH1 . ARG A 1 530 ? 43.932 70.314 -23.278 1.00 15.89 ? 530 ARG A NH1 1 ATOM 4261 N NH2 . ARG A 1 530 ? 45.433 69.415 -21.816 1.00 14.98 ? 530 ARG A NH2 1 ATOM 4262 N N . TRP A 1 531 ? 46.382 76.123 -17.455 1.00 11.04 ? 531 TRP A N 1 ATOM 4263 C CA . TRP A 1 531 ? 46.200 76.317 -15.996 1.00 10.70 ? 531 TRP A CA 1 ATOM 4264 C C . TRP A 1 531 ? 47.150 77.444 -15.581 1.00 11.70 ? 531 TRP A C 1 ATOM 4265 O O . TRP A 1 531 ? 48.345 77.348 -15.828 1.00 12.54 ? 531 TRP A O 1 ATOM 4266 C CB . TRP A 1 531 ? 46.586 75.077 -15.166 1.00 11.29 ? 531 TRP A CB 1 ATOM 4267 C CG . TRP A 1 531 ? 46.481 75.428 -13.717 1.00 13.43 ? 531 TRP A CG 1 ATOM 4268 C CD1 . TRP A 1 531 ? 47.505 75.856 -12.894 1.00 14.24 ? 531 TRP A CD1 1 ATOM 4269 C CD2 . TRP A 1 531 ? 45.294 75.512 -12.968 1.00 14.89 ? 531 TRP A CD2 1 ATOM 4270 N NE1 . TRP A 1 531 ? 46.997 76.209 -11.681 1.00 16.78 ? 531 TRP A NE1 1 ATOM 4271 C CE2 . TRP A 1 531 ? 45.644 76.015 -11.697 1.00 13.40 ? 531 TRP A CE2 1 ATOM 4272 C CE3 . TRP A 1 531 ? 43.980 75.223 -13.243 1.00 15.03 ? 531 TRP A CE3 1 ATOM 4273 C CZ2 . TRP A 1 531 ? 44.687 76.241 -10.676 1.00 15.40 ? 531 TRP A CZ2 1 ATOM 4274 C CZ3 . TRP A 1 531 ? 43.024 75.439 -12.256 1.00 15.25 ? 531 TRP A CZ3 1 ATOM 4275 C CH2 . TRP A 1 531 ? 43.391 75.950 -10.980 1.00 15.56 ? 531 TRP A CH2 1 ATOM 4276 N N . PRO A 1 532 ? 46.656 78.485 -14.904 1.00 11.49 ? 532 PRO A N 1 ATOM 4277 C CA . PRO A 1 532 ? 45.258 78.678 -14.503 1.00 13.00 ? 532 PRO A CA 1 ATOM 4278 C C . PRO A 1 532 ? 44.375 78.932 -15.687 1.00 14.00 ? 532 PRO A C 1 ATOM 4279 O O . PRO A 1 532 ? 43.143 78.790 -15.610 1.00 14.87 ? 532 PRO A O 1 ATOM 4280 C CB . PRO A 1 532 ? 45.307 79.902 -13.559 1.00 13.00 ? 532 PRO A CB 1 ATOM 4281 C CG . PRO A 1 532 ? 46.680 79.810 -12.956 1.00 14.79 ? 532 PRO A CG 1 ATOM 4282 C CD . PRO A 1 532 ? 47.556 79.412 -14.176 1.00 12.80 ? 532 PRO A CD 1 ATOM 4283 N N . GLY A 1 533 ? 44.994 79.304 -16.798 1.00 14.55 ? 533 GLY A N 1 ATOM 4284 C CA . GLY A 1 533 ? 44.216 79.561 -17.995 1.00 17.06 ? 533 GLY A CA 1 ATOM 4285 C C . GLY A 1 533 ? 44.094 80.994 -18.418 1.00 20.54 ? 533 GLY A C 1 ATOM 4286 O O . GLY A 1 533 ? 44.207 81.934 -17.593 1.00 19.45 ? 533 GLY A O 1 ATOM 4287 N N . SER A 1 534 ? 43.868 81.138 -19.729 1.00 23.35 ? 534 SER A N 1 ATOM 4288 C CA . SER A 1 534 ? 43.695 82.446 -20.361 1.00 26.10 ? 534 SER A CA 1 ATOM 4289 C C . SER A 1 534 ? 42.436 83.002 -19.770 1.00 26.35 ? 534 SER A C 1 ATOM 4290 O O . SER A 1 534 ? 41.378 82.336 -19.775 1.00 27.56 ? 534 SER A O 1 ATOM 4291 C CB . SER A 1 534 ? 43.503 82.341 -21.888 1.00 28.43 ? 534 SER A CB 1 ATOM 4292 O OG . SER A 1 534 ? 43.431 83.641 -22.466 1.00 32.20 ? 534 SER A OG 1 ATOM 4293 N N . GLY A 1 535 ? 42.527 84.227 -19.287 1.00 26.18 ? 535 GLY A N 1 ATOM 4294 C CA . GLY A 1 535 ? 41.347 84.832 -18.702 1.00 25.09 ? 535 GLY A CA 1 ATOM 4295 C C . GLY A 1 535 ? 41.220 84.520 -17.226 1.00 24.74 ? 535 GLY A C 1 ATOM 4296 O O . GLY A 1 535 ? 40.328 85.052 -16.549 1.00 25.11 ? 535 GLY A O 1 ATOM 4297 N N . VAL A 1 536 ? 42.071 83.635 -16.700 1.00 24.09 ? 536 VAL A N 1 ATOM 4298 C CA . VAL A 1 536 ? 42.004 83.344 -15.272 1.00 23.92 ? 536 VAL A CA 1 ATOM 4299 C C . VAL A 1 536 ? 43.172 84.088 -14.601 1.00 25.74 ? 536 VAL A C 1 ATOM 4300 O O . VAL A 1 536 ? 42.975 84.850 -13.644 1.00 24.71 ? 536 VAL A O 1 ATOM 4301 C CB . VAL A 1 536 ? 42.063 81.803 -14.995 1.00 22.57 ? 536 VAL A CB 1 ATOM 4302 C CG1 . VAL A 1 536 ? 41.936 81.507 -13.478 1.00 22.98 ? 536 VAL A CG1 1 ATOM 4303 C CG2 . VAL A 1 536 ? 40.864 81.105 -15.694 1.00 22.78 ? 536 VAL A CG2 1 ATOM 4304 N N . GLU A 1 537 ? 44.381 83.885 -15.113 1.00 27.46 ? 537 GLU A N 1 ATOM 4305 C CA . GLU A 1 537 ? 45.566 84.564 -14.577 1.00 29.77 ? 537 GLU A CA 1 ATOM 4306 C C . GLU A 1 537 ? 46.493 84.835 -15.772 1.00 30.37 ? 537 GLU A C 1 ATOM 4307 O O . GLU A 1 537 ? 46.705 83.938 -16.600 1.00 29.91 ? 537 GLU A O 1 ATOM 4308 C CB . GLU A 1 537 ? 46.264 83.652 -13.562 1.00 31.39 ? 537 GLU A CB 1 ATOM 4309 C CG . GLU A 1 537 ? 47.496 84.225 -12.882 1.00 35.05 ? 537 GLU A CG 1 ATOM 4310 C CD . GLU A 1 537 ? 48.041 83.293 -11.789 1.00 37.08 ? 537 GLU A CD 1 ATOM 4311 O OE1 . GLU A 1 537 ? 47.318 83.052 -10.782 1.00 38.32 ? 537 GLU A OE1 1 ATOM 4312 O OE2 . GLU A 1 537 ? 49.183 82.787 -11.936 1.00 38.26 ? 537 GLU A OE2 1 ATOM 4313 N N . ASP A 1 538 ? 47.012 86.056 -15.902 1.00 31.37 ? 538 ASP A N 1 ATOM 4314 C CA . ASP A 1 538 ? 47.944 86.345 -17.022 1.00 32.72 ? 538 ASP A CA 1 ATOM 4315 C C . ASP A 1 538 ? 49.274 85.900 -16.406 1.00 31.91 ? 538 ASP A C 1 ATOM 4316 O O . ASP A 1 538 ? 49.970 86.685 -15.745 1.00 32.85 ? 538 ASP A O 1 ATOM 4317 C CB . ASP A 1 538 ? 47.971 87.858 -17.340 1.00 35.10 ? 538 ASP A CB 1 ATOM 4318 C CG . ASP A 1 538 ? 48.690 88.180 -18.669 1.00 37.32 ? 538 ASP A CG 1 ATOM 4319 O OD1 . ASP A 1 538 ? 49.800 87.632 -18.890 1.00 38.59 ? 538 ASP A OD1 1 ATOM 4320 O OD2 . ASP A 1 538 ? 48.155 88.984 -19.496 1.00 38.41 ? 538 ASP A OD2 1 ATOM 4321 N N . SER A 1 539 ? 49.641 84.642 -16.579 1.00 29.92 ? 539 SER A N 1 ATOM 4322 C CA . SER A 1 539 ? 50.866 84.204 -15.918 1.00 28.41 ? 539 SER A CA 1 ATOM 4323 C C . SER A 1 539 ? 51.928 83.568 -16.803 1.00 26.18 ? 539 SER A C 1 ATOM 4324 O O . SER A 1 539 ? 53.040 83.291 -16.335 1.00 26.47 ? 539 SER A O 1 ATOM 4325 C CB . SER A 1 539 ? 50.520 83.228 -14.787 1.00 29.31 ? 539 SER A CB 1 ATOM 4326 O OG . SER A 1 539 ? 50.109 81.971 -15.301 1.00 30.77 ? 539 SER A OG 1 ATOM 4327 N N . ARG A 1 540 ? 51.574 83.328 -18.059 1.00 23.22 ? 540 ARG A N 1 ATOM 4328 C CA . ARG A 1 540 ? 52.505 82.705 -18.992 1.00 20.85 ? 540 ARG A CA 1 ATOM 4329 C C . ARG A 1 540 ? 53.589 83.676 -19.389 1.00 20.00 ? 540 ARG A C 1 ATOM 4330 O O . ARG A 1 540 ? 53.331 84.849 -19.557 1.00 21.27 ? 540 ARG A O 1 ATOM 4331 C CB . ARG A 1 540 ? 51.761 82.270 -20.249 1.00 20.54 ? 540 ARG A CB 1 ATOM 4332 C CG . ARG A 1 540 ? 50.928 80.975 -20.010 1.00 18.10 ? 540 ARG A CG 1 ATOM 4333 C CD . ARG A 1 540 ? 50.149 80.612 -21.221 1.00 16.80 ? 540 ARG A CD 1 ATOM 4334 N NE . ARG A 1 540 ? 51.014 79.989 -22.210 1.00 14.76 ? 540 ARG A NE 1 ATOM 4335 C CZ . ARG A 1 540 ? 50.582 79.599 -23.404 1.00 15.48 ? 540 ARG A CZ 1 ATOM 4336 N NH1 . ARG A 1 540 ? 49.303 79.762 -23.766 1.00 16.62 ? 540 ARG A NH1 1 ATOM 4337 N NH2 . ARG A 1 540 ? 51.419 79.037 -24.242 1.00 15.05 ? 540 ARG A NH2 1 ATOM 4338 N N . THR A 1 541 ? 54.802 83.169 -19.564 1.00 18.76 ? 541 THR A N 1 ATOM 4339 C CA . THR A 1 541 ? 55.864 84.055 -19.985 1.00 18.71 ? 541 THR A CA 1 ATOM 4340 C C . THR A 1 541 ? 55.949 84.084 -21.512 1.00 16.77 ? 541 THR A C 1 ATOM 4341 O O . THR A 1 541 ? 55.746 83.086 -22.195 1.00 19.79 ? 541 THR A O 1 ATOM 4342 C CB . THR A 1 541 ? 57.213 83.621 -19.445 1.00 20.89 ? 541 THR A CB 1 ATOM 4343 O OG1 . THR A 1 541 ? 57.718 82.572 -20.248 1.00 24.29 ? 541 THR A OG1 1 ATOM 4344 C CG2 . THR A 1 541 ? 57.107 83.141 -18.027 1.00 20.16 ? 541 THR A CG2 1 ATOM 4345 N N . THR A 1 542 ? 56.238 85.259 -22.027 1.00 14.91 ? 542 THR A N 1 ATOM 4346 C CA . THR A 1 542 ? 56.426 85.441 -23.443 1.00 13.36 ? 542 THR A CA 1 ATOM 4347 C C . THR A 1 542 ? 57.899 85.194 -23.744 1.00 12.16 ? 542 THR A C 1 ATOM 4348 O O . THR A 1 542 ? 58.791 85.679 -23.010 1.00 13.34 ? 542 THR A O 1 ATOM 4349 C CB . THR A 1 542 ? 56.063 86.884 -23.846 1.00 14.81 ? 542 THR A CB 1 ATOM 4350 O OG1 . THR A 1 542 ? 54.705 87.123 -23.484 1.00 16.33 ? 542 THR A OG1 1 ATOM 4351 C CG2 . THR A 1 542 ? 56.225 87.112 -25.355 1.00 14.36 ? 542 THR A CG2 1 ATOM 4352 N N . ILE A 1 543 ? 58.148 84.434 -24.812 1.00 11.79 ? 543 ILE A N 1 ATOM 4353 C CA . ILE A 1 543 ? 59.521 84.228 -25.248 1.00 11.60 ? 543 ILE A CA 1 ATOM 4354 C C . ILE A 1 543 ? 59.875 85.521 -26.031 1.00 11.47 ? 543 ILE A C 1 ATOM 4355 O O . ILE A 1 543 ? 59.252 85.840 -27.059 1.00 11.66 ? 543 ILE A O 1 ATOM 4356 C CB . ILE A 1 543 ? 59.591 83.007 -26.124 1.00 11.43 ? 543 ILE A CB 1 ATOM 4357 C CG1 . ILE A 1 543 ? 59.243 81.751 -25.252 1.00 11.86 ? 543 ILE A CG1 1 ATOM 4358 C CG2 . ILE A 1 543 ? 60.968 82.978 -26.834 1.00 11.63 ? 543 ILE A CG2 1 ATOM 4359 C CD1 . ILE A 1 543 ? 59.199 80.464 -26.067 1.00 11.33 ? 543 ILE A CD1 1 ATOM 4360 N N . ILE A 1 544 ? 60.835 86.271 -25.498 1.00 11.29 ? 544 ILE A N 1 ATOM 4361 C CA . ILE A 1 544 ? 61.203 87.562 -26.081 1.00 11.96 ? 544 ILE A CA 1 ATOM 4362 C C . ILE A 1 544 ? 62.407 87.405 -26.982 1.00 11.89 ? 544 ILE A C 1 ATOM 4363 O O . ILE A 1 544 ? 63.499 87.078 -26.520 1.00 12.19 ? 544 ILE A O 1 ATOM 4364 C CB . ILE A 1 544 ? 61.444 88.548 -24.944 1.00 14.26 ? 544 ILE A CB 1 ATOM 4365 C CG1 . ILE A 1 544 ? 60.104 88.795 -24.221 1.00 16.99 ? 544 ILE A CG1 1 ATOM 4366 C CG2 . ILE A 1 544 ? 61.964 89.872 -25.514 1.00 15.41 ? 544 ILE A CG2 1 ATOM 4367 C CD1 . ILE A 1 544 ? 60.160 89.692 -23.003 1.00 19.12 ? 544 ILE A CD1 1 ATOM 4368 N N . LEU A 1 545 ? 62.170 87.617 -28.268 1.00 11.65 ? 545 LEU A N 1 ATOM 4369 C CA . LEU A 1 545 ? 63.191 87.495 -29.293 1.00 11.88 ? 545 LEU A CA 1 ATOM 4370 C C . LEU A 1 545 ? 63.303 88.843 -29.996 1.00 12.77 ? 545 LEU A C 1 ATOM 4371 O O . LEU A 1 545 ? 62.341 89.613 -30.033 1.00 14.07 ? 545 LEU A O 1 ATOM 4372 C CB . LEU A 1 545 ? 62.797 86.424 -30.317 1.00 12.04 ? 545 LEU A CB 1 ATOM 4373 C CG . LEU A 1 545 ? 62.596 85.034 -29.730 1.00 11.86 ? 545 LEU A CG 1 ATOM 4374 C CD1 . LEU A 1 545 ? 62.126 84.103 -30.856 1.00 13.87 ? 545 LEU A CD1 1 ATOM 4375 C CD2 . LEU A 1 545 ? 63.895 84.490 -29.109 1.00 12.79 ? 545 LEU A CD2 1 ATOM 4376 N N . GLY A 1 546 ? 64.475 89.108 -30.552 1.00 13.00 ? 546 GLY A N 1 ATOM 4377 C CA . GLY A 1 546 ? 64.656 90.374 -31.271 1.00 13.96 ? 546 GLY A CA 1 ATOM 4378 C C . GLY A 1 546 ? 66.096 90.467 -31.708 1.00 14.35 ? 546 GLY A C 1 ATOM 4379 O O . GLY A 1 546 ? 67.012 89.980 -31.022 1.00 13.56 ? 546 GLY A O 1 ATOM 4380 N N . GLU A 1 547 ? 66.323 91.143 -32.829 1.00 15.94 ? 547 GLU A N 1 ATOM 4381 C CA . GLU A 1 547 ? 67.686 91.254 -33.350 1.00 18.53 ? 547 GLU A CA 1 ATOM 4382 C C . GLU A 1 547 ? 68.654 91.920 -32.402 1.00 17.65 ? 547 GLU A C 1 ATOM 4383 O O . GLU A 1 547 ? 69.836 91.608 -32.388 1.00 20.32 ? 547 GLU A O 1 ATOM 4384 C CB . GLU A 1 547 ? 67.697 92.031 -34.671 1.00 22.01 ? 547 GLU A CB 1 ATOM 4385 C CG . GLU A 1 547 ? 69.037 91.877 -35.405 1.00 28.20 ? 547 GLU A CG 1 ATOM 4386 C CD . GLU A 1 547 ? 69.138 92.752 -36.653 1.00 31.26 ? 547 GLU A CD 1 ATOM 4387 O OE1 . GLU A 1 547 ? 68.103 92.929 -37.357 1.00 33.80 ? 547 GLU A OE1 1 ATOM 4388 O OE2 . GLU A 1 547 ? 70.258 93.259 -36.936 1.00 34.31 ? 547 GLU A OE2 1 ATOM 4389 N N . ASP A 1 548 ? 68.125 92.823 -31.595 1.00 16.17 ? 548 ASP A N 1 ATOM 4390 C CA . ASP A 1 548 ? 68.962 93.535 -30.660 1.00 16.62 ? 548 ASP A CA 1 ATOM 4391 C C . ASP A 1 548 ? 68.892 92.945 -29.265 1.00 16.72 ? 548 ASP A C 1 ATOM 4392 O O . ASP A 1 548 ? 69.278 93.609 -28.287 1.00 18.40 ? 548 ASP A O 1 ATOM 4393 C CB . ASP A 1 548 ? 68.547 95.010 -30.612 1.00 17.77 ? 548 ASP A CB 1 ATOM 4394 C CG . ASP A 1 548 ? 68.776 95.722 -31.929 1.00 19.27 ? 548 ASP A CG 1 ATOM 4395 O OD1 . ASP A 1 548 ? 69.939 95.724 -32.383 1.00 22.02 ? 548 ASP A OD1 1 ATOM 4396 O OD2 . ASP A 1 548 ? 67.808 96.258 -32.502 1.00 21.88 ? 548 ASP A OD2 1 ATOM 4397 N N . ILE A 1 549 ? 68.411 91.702 -29.131 1.00 15.00 ? 549 ILE A N 1 ATOM 4398 C CA . ILE A 1 549 ? 68.402 91.114 -27.796 1.00 14.96 ? 549 ILE A CA 1 ATOM 4399 C C . ILE A 1 549 ? 68.678 89.611 -27.777 1.00 13.87 ? 549 ILE A C 1 ATOM 4400 O O . ILE A 1 549 ? 69.535 89.181 -27.009 1.00 14.39 ? 549 ILE A O 1 ATOM 4401 C CB . ILE A 1 549 ? 67.067 91.417 -26.986 1.00 14.66 ? 549 ILE A CB 1 ATOM 4402 C CG1 . ILE A 1 549 ? 67.209 90.862 -25.545 1.00 15.65 ? 549 ILE A CG1 1 ATOM 4403 C CG2 . ILE A 1 549 ? 65.800 90.938 -27.735 1.00 13.58 ? 549 ILE A CG2 1 ATOM 4404 C CD1 . ILE A 1 549 ? 66.017 91.200 -24.602 1.00 18.47 ? 549 ILE A CD1 1 ATOM 4405 N N . LEU A 1 550 ? 67.995 88.847 -28.641 1.00 12.51 ? 550 LEU A N 1 ATOM 4406 C CA . LEU A 1 550 ? 68.128 87.380 -28.571 1.00 12.45 ? 550 LEU A CA 1 ATOM 4407 C C . LEU A 1 550 ? 67.500 86.810 -29.828 1.00 12.34 ? 550 LEU A C 1 ATOM 4408 O O . LEU A 1 550 ? 66.284 86.946 -30.063 1.00 12.93 ? 550 LEU A O 1 ATOM 4409 C CB . LEU A 1 550 ? 67.356 86.856 -27.349 1.00 13.19 ? 550 LEU A CB 1 ATOM 4410 C CG . LEU A 1 550 ? 67.469 85.346 -27.145 1.00 13.85 ? 550 LEU A CG 1 ATOM 4411 C CD1 . LEU A 1 550 ? 68.930 84.937 -26.884 1.00 15.32 ? 550 LEU A CD1 1 ATOM 4412 C CD2 . LEU A 1 550 ? 66.569 84.982 -25.953 1.00 15.13 ? 550 LEU A CD2 1 ATOM 4413 N N . PRO A 1 551 ? 68.286 86.123 -30.640 1.00 12.30 ? 551 PRO A N 1 ATOM 4414 C CA . PRO A 1 551 ? 67.728 85.578 -31.863 1.00 13.16 ? 551 PRO A CA 1 ATOM 4415 C C . PRO A 1 551 ? 66.833 84.333 -31.755 1.00 12.30 ? 551 PRO A C 1 ATOM 4416 O O . PRO A 1 551 ? 65.978 84.111 -32.637 1.00 13.33 ? 551 PRO A O 1 ATOM 4417 C CB . PRO A 1 551 ? 68.970 85.207 -32.701 1.00 14.02 ? 551 PRO A CB 1 ATOM 4418 C CG . PRO A 1 551 ? 70.044 85.950 -32.138 1.00 17.36 ? 551 PRO A CG 1 ATOM 4419 C CD . PRO A 1 551 ? 69.759 86.133 -30.671 1.00 14.23 ? 551 PRO A CD 1 ATOM 4420 N N . SER A 1 552 ? 67.099 83.502 -30.741 1.00 10.92 ? 552 SER A N 1 ATOM 4421 C CA . SER A 1 552 ? 66.385 82.223 -30.717 1.00 11.37 ? 552 SER A CA 1 ATOM 4422 C C . SER A 1 552 ? 66.285 81.736 -29.294 1.00 10.31 ? 552 SER A C 1 ATOM 4423 O O . SER A 1 552 ? 66.946 82.227 -28.394 1.00 10.78 ? 552 SER A O 1 ATOM 4424 C CB . SER A 1 552 ? 67.158 81.194 -31.565 1.00 12.71 ? 552 SER A CB 1 ATOM 4425 O OG . SER A 1 552 ? 68.414 80.870 -31.013 1.00 14.05 ? 552 SER A OG 1 ATOM 4426 N N . LYS A 1 553 ? 65.437 80.724 -29.111 1.00 10.30 ? 553 LYS A N 1 ATOM 4427 C CA . LYS A 1 553 ? 65.181 80.158 -27.782 1.00 9.50 ? 553 LYS A CA 1 ATOM 4428 C C . LYS A 1 553 ? 64.894 78.665 -27.894 1.00 8.90 ? 553 LYS A C 1 ATOM 4429 O O . LYS A 1 553 ? 64.083 78.217 -28.728 1.00 9.64 ? 553 LYS A O 1 ATOM 4430 C CB . LYS A 1 553 ? 63.896 80.853 -27.234 1.00 10.56 ? 553 LYS A CB 1 ATOM 4431 C CG . LYS A 1 553 ? 63.387 80.222 -25.898 1.00 11.92 ? 553 LYS A CG 1 ATOM 4432 C CD . LYS A 1 553 ? 64.431 80.371 -24.777 1.00 11.86 ? 553 LYS A CD 1 ATOM 4433 C CE . LYS A 1 553 ? 64.655 81.838 -24.310 1.00 12.84 ? 553 LYS A CE 1 ATOM 4434 N NZ . LYS A 1 553 ? 65.860 81.949 -23.459 1.00 11.94 ? 553 LYS A NZ 1 ATOM 4435 N N . HIS A 1 554 ? 65.523 77.901 -27.002 1.00 9.09 ? 554 HIS A N 1 ATOM 4436 C CA . HIS A 1 554 ? 65.228 76.463 -26.931 1.00 8.85 ? 554 HIS A CA 1 ATOM 4437 C C . HIS A 1 554 ? 64.051 76.214 -25.999 1.00 8.33 ? 554 HIS A C 1 ATOM 4438 O O . HIS A 1 554 ? 63.896 76.852 -24.945 1.00 9.27 ? 554 HIS A O 1 ATOM 4439 C CB . HIS A 1 554 ? 66.424 75.689 -26.344 1.00 11.38 ? 554 HIS A CB 1 ATOM 4440 C CG . HIS A 1 554 ? 67.560 75.573 -27.299 1.00 13.41 ? 554 HIS A CG 1 ATOM 4441 N ND1 . HIS A 1 554 ? 68.223 74.400 -27.562 1.00 18.14 ? 554 HIS A ND1 1 ATOM 4442 C CD2 . HIS A 1 554 ? 68.175 76.533 -28.043 1.00 15.73 ? 554 HIS A CD2 1 ATOM 4443 C CE1 . HIS A 1 554 ? 69.227 74.643 -28.391 1.00 15.32 ? 554 HIS A CE1 1 ATOM 4444 N NE2 . HIS A 1 554 ? 69.218 75.927 -28.696 1.00 20.33 ? 554 HIS A NE2 1 ATOM 4445 N N . VAL A 1 555 ? 63.212 75.298 -26.432 1.00 7.77 ? 555 VAL A N 1 ATOM 4446 C CA . VAL A 1 555 ? 62.049 74.812 -25.667 1.00 8.80 ? 555 VAL A CA 1 ATOM 4447 C C . VAL A 1 555 ? 62.142 73.293 -25.664 1.00 8.33 ? 555 VAL A C 1 ATOM 4448 O O . VAL A 1 555 ? 62.685 72.685 -26.584 1.00 8.95 ? 555 VAL A O 1 ATOM 4449 C CB . VAL A 1 555 ? 60.685 75.279 -26.216 1.00 8.44 ? 555 VAL A CB 1 ATOM 4450 C CG1 . VAL A 1 555 ? 60.598 76.810 -26.183 1.00 8.85 ? 555 VAL A CG1 1 ATOM 4451 C CG2 . VAL A 1 555 ? 60.455 74.776 -27.607 1.00 9.81 ? 555 VAL A CG2 1 ATOM 4452 N N . VAL A 1 556 ? 61.655 72.666 -24.590 1.00 7.65 ? 556 VAL A N 1 ATOM 4453 C CA . VAL A 1 556 ? 61.701 71.209 -24.435 1.00 7.81 ? 556 VAL A CA 1 ATOM 4454 C C . VAL A 1 556 ? 60.327 70.707 -24.017 1.00 6.88 ? 556 VAL A C 1 ATOM 4455 O O . VAL A 1 556 ? 59.665 71.295 -23.138 1.00 7.85 ? 556 VAL A O 1 ATOM 4456 C CB . VAL A 1 556 ? 62.707 70.821 -23.319 1.00 7.78 ? 556 VAL A CB 1 ATOM 4457 C CG1 . VAL A 1 556 ? 62.627 69.319 -23.025 1.00 8.60 ? 556 VAL A CG1 1 ATOM 4458 C CG2 . VAL A 1 556 ? 64.097 71.233 -23.714 1.00 9.43 ? 556 VAL A CG2 1 ATOM 4459 N N . MET A 1 557 ? 59.898 69.625 -24.632 1.00 7.25 ? 557 MET A N 1 ATOM 4460 C CA . MET A 1 557 ? 58.651 68.946 -24.274 1.00 7.18 ? 557 MET A CA 1 ATOM 4461 C C . MET A 1 557 ? 58.939 67.626 -23.604 1.00 7.12 ? 557 MET A C 1 ATOM 4462 O O . MET A 1 557 ? 59.836 66.877 -24.003 1.00 7.97 ? 557 MET A O 1 ATOM 4463 C CB . MET A 1 557 ? 57.763 68.660 -25.521 1.00 7.38 ? 557 MET A CB 1 ATOM 4464 C CG . MET A 1 557 ? 56.749 69.805 -25.827 1.00 8.91 ? 557 MET A CG 1 ATOM 4465 S SD . MET A 1 557 ? 57.399 71.457 -26.026 1.00 9.85 ? 557 MET A SD 1 ATOM 4466 C CE . MET A 1 557 ? 57.629 72.041 -24.429 1.00 19.51 ? 557 MET A CE 1 ATOM 4467 N N . HIS A 1 558 ? 58.148 67.330 -22.565 1.00 7.09 ? 558 HIS A N 1 ATOM 4468 C CA . HIS A 1 558 ? 58.224 66.043 -21.879 1.00 6.00 ? 558 HIS A CA 1 ATOM 4469 C C . HIS A 1 558 ? 56.916 65.296 -22.115 1.00 7.32 ? 558 HIS A C 1 ATOM 4470 O O . HIS A 1 558 ? 55.806 65.872 -22.104 1.00 7.10 ? 558 HIS A O 1 ATOM 4471 C CB . HIS A 1 558 ? 58.371 66.236 -20.356 1.00 7.29 ? 558 HIS A CB 1 ATOM 4472 C CG . HIS A 1 558 ? 58.246 64.967 -19.568 1.00 7.19 ? 558 HIS A CG 1 ATOM 4473 N ND1 . HIS A 1 558 ? 57.305 64.793 -18.565 1.00 7.44 ? 558 HIS A ND1 1 ATOM 4474 C CD2 . HIS A 1 558 ? 58.995 63.837 -19.586 1.00 7.39 ? 558 HIS A CD2 1 ATOM 4475 C CE1 . HIS A 1 558 ? 57.500 63.601 -18.001 1.00 7.65 ? 558 HIS A CE1 1 ATOM 4476 N NE2 . HIS A 1 558 ? 58.515 63.003 -18.599 1.00 7.53 ? 558 HIS A NE2 1 ATOM 4477 N N . ASN A 1 559 ? 57.041 63.989 -22.306 1.00 7.03 ? 559 ASN A N 1 ATOM 4478 C CA . ASN A 1 559 ? 55.899 63.110 -22.507 1.00 6.38 ? 559 ASN A CA 1 ATOM 4479 C C . ASN A 1 559 ? 55.902 62.019 -21.445 1.00 6.75 ? 559 ASN A C 1 ATOM 4480 O O . ASN A 1 559 ? 56.654 61.071 -21.544 1.00 8.15 ? 559 ASN A O 1 ATOM 4481 C CB . ASN A 1 559 ? 55.995 62.451 -23.903 1.00 7.19 ? 559 ASN A CB 1 ATOM 4482 C CG . ASN A 1 559 ? 54.972 61.369 -24.099 1.00 7.97 ? 559 ASN A CG 1 ATOM 4483 O OD1 . ASN A 1 559 ? 53.884 61.352 -23.519 1.00 7.75 ? 559 ASN A OD1 1 ATOM 4484 N ND2 . ASN A 1 559 ? 55.285 60.455 -25.007 1.00 9.20 ? 559 ASN A ND2 1 ATOM 4485 N N . THR A 1 560 ? 55.030 62.152 -20.445 1.00 6.47 ? 560 THR A N 1 ATOM 4486 C CA . THR A 1 560 ? 55.033 61.167 -19.346 1.00 7.17 ? 560 THR A CA 1 ATOM 4487 C C . THR A 1 560 ? 54.427 59.821 -19.735 1.00 6.95 ? 560 THR A C 1 ATOM 4488 O O . THR A 1 560 ? 54.615 58.856 -19.021 1.00 7.54 ? 560 THR A O 1 ATOM 4489 C CB . THR A 1 560 ? 54.263 61.800 -18.162 1.00 6.26 ? 560 THR A CB 1 ATOM 4490 O OG1 . THR A 1 560 ? 54.540 61.043 -16.956 1.00 7.74 ? 560 THR A OG1 1 ATOM 4491 C CG2 . THR A 1 560 ? 52.762 61.767 -18.366 1.00 8.13 ? 560 THR A CG2 1 ATOM 4492 N N . LEU A 1 561 ? 53.683 59.755 -20.854 1.00 7.50 ? 561 LEU A N 1 ATOM 4493 C CA . LEU A 1 561 ? 53.067 58.488 -21.260 1.00 8.17 ? 561 LEU A CA 1 ATOM 4494 C C . LEU A 1 561 ? 54.091 57.561 -21.942 1.00 7.58 ? 561 LEU A C 1 ATOM 4495 O O . LEU A 1 561 ? 54.970 58.033 -22.676 1.00 8.25 ? 561 LEU A O 1 ATOM 4496 C CB . LEU A 1 561 ? 51.905 58.734 -22.271 1.00 8.53 ? 561 LEU A CB 1 ATOM 4497 C CG . LEU A 1 561 ? 50.823 59.663 -21.723 1.00 8.52 ? 561 LEU A CG 1 ATOM 4498 C CD1 . LEU A 1 561 ? 49.728 59.772 -22.778 1.00 9.72 ? 561 LEU A CD1 1 ATOM 4499 C CD2 . LEU A 1 561 ? 50.176 59.078 -20.480 1.00 10.12 ? 561 LEU A CD2 1 ATOM 4500 N N . PRO A 1 562 ? 53.920 56.248 -21.797 1.00 7.64 ? 562 PRO A N 1 ATOM 4501 C CA . PRO A 1 562 ? 54.873 55.285 -22.382 1.00 9.06 ? 562 PRO A CA 1 ATOM 4502 C C . PRO A 1 562 ? 54.676 54.921 -23.823 1.00 9.13 ? 562 PRO A C 1 ATOM 4503 O O . PRO A 1 562 ? 54.804 53.767 -24.202 1.00 10.23 ? 562 PRO A O 1 ATOM 4504 C CB . PRO A 1 562 ? 54.767 54.087 -21.424 1.00 8.66 ? 562 PRO A CB 1 ATOM 4505 C CG . PRO A 1 562 ? 53.229 54.067 -21.130 1.00 8.08 ? 562 PRO A CG 1 ATOM 4506 C CD . PRO A 1 562 ? 52.977 55.569 -20.894 1.00 8.34 ? 562 PRO A CD 1 ATOM 4507 N N . HIS A 1 563 ? 54.312 55.906 -24.641 1.00 9.45 ? 563 HIS A N 1 ATOM 4508 C CA . HIS A 1 563 ? 54.247 55.676 -26.096 1.00 9.50 ? 563 HIS A CA 1 ATOM 4509 C C . HIS A 1 563 ? 54.616 56.980 -26.762 1.00 10.29 ? 563 HIS A C 1 ATOM 4510 O O . HIS A 1 563 ? 54.490 58.061 -26.163 1.00 10.29 ? 563 HIS A O 1 ATOM 4511 C CB . HIS A 1 563 ? 52.843 55.180 -26.546 1.00 9.67 ? 563 HIS A CB 1 ATOM 4512 C CG . HIS A 1 563 ? 51.712 56.052 -26.104 1.00 10.11 ? 563 HIS A CG 1 ATOM 4513 N ND1 . HIS A 1 563 ? 50.889 55.688 -25.059 1.00 10.61 ? 563 HIS A ND1 1 ATOM 4514 C CD2 . HIS A 1 563 ? 51.199 57.204 -26.613 1.00 10.12 ? 563 HIS A CD2 1 ATOM 4515 C CE1 . HIS A 1 563 ? 49.906 56.584 -24.947 1.00 11.47 ? 563 HIS A CE1 1 ATOM 4516 N NE2 . HIS A 1 563 ? 50.081 57.519 -25.874 1.00 11.89 ? 563 HIS A NE2 1 ATOM 4517 N N . TRP A 1 564 ? 55.152 56.898 -27.985 1.00 10.33 ? 564 TRP A N 1 ATOM 4518 C CA . TRP A 1 564 ? 55.476 58.119 -28.735 1.00 9.98 ? 564 TRP A CA 1 ATOM 4519 C C . TRP A 1 564 ? 54.224 58.938 -28.864 1.00 10.83 ? 564 TRP A C 1 ATOM 4520 O O . TRP A 1 564 ? 53.114 58.427 -29.075 1.00 11.26 ? 564 TRP A O 1 ATOM 4521 C CB . TRP A 1 564 ? 55.937 57.751 -30.160 1.00 11.74 ? 564 TRP A CB 1 ATOM 4522 C CG . TRP A 1 564 ? 57.321 57.291 -30.246 1.00 11.02 ? 564 TRP A CG 1 ATOM 4523 C CD1 . TRP A 1 564 ? 57.780 55.985 -30.126 1.00 13.09 ? 564 TRP A CD1 1 ATOM 4524 C CD2 . TRP A 1 564 ? 58.488 58.110 -30.407 1.00 11.89 ? 564 TRP A CD2 1 ATOM 4525 N NE1 . TRP A 1 564 ? 59.140 55.968 -30.197 1.00 14.25 ? 564 TRP A NE1 1 ATOM 4526 C CE2 . TRP A 1 564 ? 59.611 57.245 -30.367 1.00 12.84 ? 564 TRP A CE2 1 ATOM 4527 C CE3 . TRP A 1 564 ? 58.699 59.493 -30.577 1.00 12.77 ? 564 TRP A CE3 1 ATOM 4528 C CZ2 . TRP A 1 564 ? 60.931 57.718 -30.481 1.00 13.47 ? 564 TRP A CZ2 1 ATOM 4529 C CZ3 . TRP A 1 564 ? 60.019 59.956 -30.694 1.00 13.18 ? 564 TRP A CZ3 1 ATOM 4530 C CH2 . TRP A 1 564 ? 61.107 59.072 -30.643 1.00 14.37 ? 564 TRP A CH2 1 ATOM 4531 N N . ARG A 1 565 ? 54.391 60.250 -28.749 1.00 11.29 ? 565 ARG A N 1 ATOM 4532 C CA . ARG A 1 565 ? 53.239 61.084 -28.899 1.00 12.17 ? 565 ARG A CA 1 ATOM 4533 C C . ARG A 1 565 ? 53.595 62.296 -29.740 1.00 11.87 ? 565 ARG A C 1 ATOM 4534 O O . ARG A 1 565 ? 54.688 62.875 -29.618 1.00 13.17 ? 565 ARG A O 1 ATOM 4535 C CB . ARG A 1 565 ? 52.779 61.532 -27.500 1.00 15.10 ? 565 ARG A CB 1 ATOM 4536 C CG . ARG A 1 565 ? 51.463 62.208 -27.425 1.00 18.06 ? 565 ARG A CG 1 ATOM 4537 C CD . ARG A 1 565 ? 50.662 61.828 -26.109 1.00 15.04 ? 565 ARG A CD 1 ATOM 4538 N NE . ARG A 1 565 ? 51.414 62.138 -24.905 1.00 14.26 ? 565 ARG A NE 1 ATOM 4539 C CZ . ARG A 1 565 ? 50.859 62.777 -23.869 1.00 11.23 ? 565 ARG A CZ 1 ATOM 4540 N NH1 . ARG A 1 565 ? 49.557 63.176 -23.865 1.00 11.19 ? 565 ARG A NH1 1 ATOM 4541 N NH2 . ARG A 1 565 ? 51.658 63.067 -22.837 1.00 10.77 ? 565 ARG A NH2 1 ATOM 4542 N N . GLU A 1 566 ? 52.693 62.639 -30.641 1.00 13.32 ? 566 GLU A N 1 ATOM 4543 C CA . GLU A 1 566 ? 52.794 63.882 -31.372 1.00 15.96 ? 566 GLU A CA 1 ATOM 4544 C C . GLU A 1 566 ? 51.621 64.692 -30.760 1.00 17.56 ? 566 GLU A C 1 ATOM 4545 O O . GLU A 1 566 ? 50.562 64.129 -30.378 1.00 19.88 ? 566 GLU A O 1 ATOM 4546 C CB . GLU A 1 566 ? 52.582 63.649 -32.823 1.00 19.46 ? 566 GLU A CB 1 ATOM 4547 C CG . GLU A 1 566 ? 53.717 63.106 -33.461 1.00 20.93 ? 566 GLU A CG 1 ATOM 4548 C CD . GLU A 1 566 ? 53.452 63.016 -34.944 1.00 25.08 ? 566 GLU A CD 1 ATOM 4549 O OE1 . GLU A 1 566 ? 52.312 62.611 -35.304 1.00 27.42 ? 566 GLU A OE1 1 ATOM 4550 O OE2 . GLU A 1 566 ? 54.375 63.381 -35.713 1.00 25.86 ? 566 GLU A OE2 1 ATOM 4551 N N . GLN A 1 567 ? 51.778 66.003 -30.628 1.00 14.61 ? 567 GLN A N 1 ATOM 4552 C CA . GLN A 1 567 ? 50.678 66.793 -30.039 1.00 14.34 ? 567 GLN A CA 1 ATOM 4553 C C . GLN A 1 567 ? 51.054 68.230 -30.401 1.00 13.39 ? 567 GLN A C 1 ATOM 4554 O O . GLN A 1 567 ? 52.241 68.576 -30.401 1.00 11.52 ? 567 GLN A O 1 ATOM 4555 C CB . GLN A 1 567 ? 50.605 66.645 -28.473 1.00 15.24 ? 567 GLN A CB 1 ATOM 4556 C CG . GLN A 1 567 ? 49.468 67.521 -27.712 1.00 16.43 ? 567 GLN A CG 1 ATOM 4557 C CD . GLN A 1 567 ? 49.860 68.045 -26.278 1.00 17.86 ? 567 GLN A CD 1 ATOM 4558 O OE1 . GLN A 1 567 ? 49.854 67.258 -25.267 1.00 13.06 ? 567 GLN A OE1 1 ATOM 4559 N NE2 . GLN A 1 567 ? 50.181 69.396 -26.185 1.00 17.24 ? 567 GLN A NE2 1 ATOM 4560 N N . LEU A 1 568 ? 50.077 69.038 -30.763 1.00 11.24 ? 568 LEU A N 1 ATOM 4561 C CA . LEU A 1 568 ? 50.382 70.469 -30.999 1.00 10.93 ? 568 LEU A CA 1 ATOM 4562 C C . LEU A 1 568 ? 50.666 71.091 -29.641 1.00 10.13 ? 568 LEU A C 1 ATOM 4563 O O . LEU A 1 568 ? 50.001 70.769 -28.597 1.00 11.08 ? 568 LEU A O 1 ATOM 4564 C CB . LEU A 1 568 ? 49.170 71.194 -31.608 1.00 12.23 ? 568 LEU A CB 1 ATOM 4565 C CG . LEU A 1 568 ? 48.794 70.847 -33.049 1.00 13.81 ? 568 LEU A CG 1 ATOM 4566 C CD1 . LEU A 1 568 ? 47.713 71.861 -33.511 1.00 15.40 ? 568 LEU A CD1 1 ATOM 4567 C CD2 . LEU A 1 568 ? 49.964 70.984 -33.978 1.00 15.14 ? 568 LEU A CD2 1 ATOM 4568 N N . VAL A 1 569 ? 51.668 71.953 -29.644 1.00 8.46 ? 569 VAL A N 1 ATOM 4569 C CA . VAL A 1 569 ? 52.036 72.720 -28.466 1.00 9.46 ? 569 VAL A CA 1 ATOM 4570 C C . VAL A 1 569 ? 52.088 74.185 -28.862 1.00 10.20 ? 569 VAL A C 1 ATOM 4571 O O . VAL A 1 569 ? 52.302 74.506 -30.039 1.00 11.33 ? 569 VAL A O 1 ATOM 4572 C CB . VAL A 1 569 ? 53.432 72.331 -27.872 1.00 8.76 ? 569 VAL A CB 1 ATOM 4573 C CG1 . VAL A 1 569 ? 53.328 70.915 -27.231 1.00 10.46 ? 569 VAL A CG1 1 ATOM 4574 C CG2 . VAL A 1 569 ? 54.561 72.382 -28.933 1.00 9.48 ? 569 VAL A CG2 1 ATOM 4575 N N . ASP A 1 570 ? 51.867 75.077 -27.919 1.00 9.99 ? 570 ASP A N 1 ATOM 4576 C CA . ASP A 1 570 ? 51.912 76.498 -28.236 1.00 10.99 ? 570 ASP A CA 1 ATOM 4577 C C . ASP A 1 570 ? 52.684 77.278 -27.197 1.00 10.44 ? 570 ASP A C 1 ATOM 4578 O O . ASP A 1 570 ? 52.769 76.887 -26.009 1.00 11.77 ? 570 ASP A O 1 ATOM 4579 C CB . ASP A 1 570 ? 50.478 77.075 -28.376 1.00 13.78 ? 570 ASP A CB 1 ATOM 4580 C CG . ASP A 1 570 ? 49.747 77.184 -27.023 1.00 17.46 ? 570 ASP A CG 1 ATOM 4581 O OD1 . ASP A 1 570 ? 49.539 76.163 -26.366 1.00 23.94 ? 570 ASP A OD1 1 ATOM 4582 O OD2 . ASP A 1 570 ? 49.381 78.290 -26.604 1.00 21.88 ? 570 ASP A OD2 1 ATOM 4583 N N . PHE A 1 571 ? 53.300 78.358 -27.664 1.00 9.35 ? 571 PHE A N 1 ATOM 4584 C CA . PHE A 1 571 ? 54.049 79.275 -26.820 1.00 9.71 ? 571 PHE A CA 1 ATOM 4585 C C . PHE A 1 571 ? 53.717 80.702 -27.198 1.00 9.66 ? 571 PHE A C 1 ATOM 4586 O O . PHE A 1 571 ? 53.306 80.957 -28.322 1.00 10.91 ? 571 PHE A O 1 ATOM 4587 C CB . PHE A 1 571 ? 55.563 79.104 -27.042 1.00 9.49 ? 571 PHE A CB 1 ATOM 4588 C CG . PHE A 1 571 ? 56.073 77.763 -26.643 1.00 8.65 ? 571 PHE A CG 1 ATOM 4589 C CD1 . PHE A 1 571 ? 56.071 76.675 -27.499 1.00 9.42 ? 571 PHE A CD1 1 ATOM 4590 C CD2 . PHE A 1 571 ? 56.531 77.592 -25.353 1.00 9.20 ? 571 PHE A CD2 1 ATOM 4591 C CE1 . PHE A 1 571 ? 56.519 75.434 -27.074 1.00 8.95 ? 571 PHE A CE1 1 ATOM 4592 C CE2 . PHE A 1 571 ? 56.982 76.334 -24.914 1.00 9.30 ? 571 PHE A CE2 1 ATOM 4593 C CZ . PHE A 1 571 ? 56.972 75.251 -25.786 1.00 10.05 ? 571 PHE A CZ 1 ATOM 4594 N N . TYR A 1 572 ? 53.850 81.601 -26.252 1.00 9.01 ? 572 TYR A N 1 ATOM 4595 C CA . TYR A 1 572 ? 53.731 83.029 -26.534 1.00 9.57 ? 572 TYR A CA 1 ATOM 4596 C C . TYR A 1 572 ? 55.101 83.535 -26.947 1.00 10.13 ? 572 TYR A C 1 ATOM 4597 O O . TYR A 1 572 ? 56.123 83.199 -26.310 1.00 10.30 ? 572 TYR A O 1 ATOM 4598 C CB . TYR A 1 572 ? 53.275 83.805 -25.294 1.00 11.21 ? 572 TYR A CB 1 ATOM 4599 C CG . TYR A 1 572 ? 51.823 83.672 -24.909 1.00 12.50 ? 572 TYR A CG 1 ATOM 4600 C CD1 . TYR A 1 572 ? 50.923 82.981 -25.699 1.00 14.56 ? 572 TYR A CD1 1 ATOM 4601 C CD2 . TYR A 1 572 ? 51.375 84.277 -23.729 1.00 16.20 ? 572 TYR A CD2 1 ATOM 4602 C CE1 . TYR A 1 572 ? 49.578 82.880 -25.329 1.00 16.41 ? 572 TYR A CE1 1 ATOM 4603 C CE2 . TYR A 1 572 ? 50.023 84.179 -23.349 1.00 17.20 ? 572 TYR A CE2 1 ATOM 4604 C CZ . TYR A 1 572 ? 49.162 83.477 -24.163 1.00 16.76 ? 572 TYR A CZ 1 ATOM 4605 O OH . TYR A 1 572 ? 47.807 83.324 -23.789 1.00 20.80 ? 572 TYR A OH 1 ATOM 4606 N N . VAL A 1 573 ? 55.130 84.348 -28.014 1.00 10.47 ? 573 VAL A N 1 ATOM 4607 C CA . VAL A 1 573 ? 56.370 84.936 -28.545 1.00 10.62 ? 573 VAL A CA 1 ATOM 4608 C C . VAL A 1 573 ? 56.132 86.412 -28.823 1.00 9.49 ? 573 VAL A C 1 ATOM 4609 O O . VAL A 1 573 ? 55.025 86.849 -29.074 1.00 10.53 ? 573 VAL A O 1 ATOM 4610 C CB . VAL A 1 573 ? 56.822 84.209 -29.861 1.00 11.05 ? 573 VAL A CB 1 ATOM 4611 C CG1 . VAL A 1 573 ? 57.391 82.848 -29.529 1.00 13.21 ? 573 VAL A CG1 1 ATOM 4612 C CG2 . VAL A 1 573 ? 55.658 84.076 -30.832 1.00 11.30 ? 573 VAL A CG2 1 ATOM 4613 N N . SER A 1 574 ? 57.212 87.167 -28.821 1.00 10.75 ? 574 SER A N 1 ATOM 4614 C CA . SER A 1 574 ? 57.114 88.629 -29.000 1.00 11.78 ? 574 SER A CA 1 ATOM 4615 C C . SER A 1 574 ? 57.102 89.130 -30.409 1.00 12.12 ? 574 SER A C 1 ATOM 4616 O O . SER A 1 574 ? 57.086 90.361 -30.632 1.00 14.68 ? 574 SER A O 1 ATOM 4617 C CB . SER A 1 574 ? 58.227 89.271 -28.212 1.00 11.60 ? 574 SER A CB 1 ATOM 4618 O OG . SER A 1 574 ? 59.491 88.951 -28.765 1.00 12.51 ? 574 SER A OG 1 ATOM 4619 N N . SER A 1 575 ? 57.101 88.228 -31.377 1.00 12.79 ? 575 SER A N 1 ATOM 4620 C CA . SER A 1 575 ? 57.049 88.582 -32.787 1.00 13.77 ? 575 SER A CA 1 ATOM 4621 C C . SER A 1 575 ? 56.285 87.513 -33.544 1.00 14.45 ? 575 SER A C 1 ATOM 4622 O O . SER A 1 575 ? 56.292 86.324 -33.165 1.00 13.14 ? 575 SER A O 1 ATOM 4623 C CB . SER A 1 575 ? 58.455 88.605 -33.369 1.00 14.08 ? 575 SER A CB 1 ATOM 4624 O OG . SER A 1 575 ? 58.451 88.716 -34.801 1.00 15.34 ? 575 SER A OG 1 ATOM 4625 N N . PRO A 1 576 ? 55.576 87.898 -34.600 1.00 14.04 ? 576 PRO A N 1 ATOM 4626 C CA . PRO A 1 576 ? 54.861 86.882 -35.367 1.00 14.12 ? 576 PRO A CA 1 ATOM 4627 C C . PRO A 1 576 ? 55.798 86.178 -36.362 1.00 12.79 ? 576 PRO A C 1 ATOM 4628 O O . PRO A 1 576 ? 55.432 85.147 -36.943 1.00 14.18 ? 576 PRO A O 1 ATOM 4629 C CB . PRO A 1 576 ? 53.769 87.668 -36.063 1.00 15.41 ? 576 PRO A CB 1 ATOM 4630 C CG . PRO A 1 576 ? 54.367 89.058 -36.236 1.00 16.50 ? 576 PRO A CG 1 ATOM 4631 C CD . PRO A 1 576 ? 55.290 89.277 -35.068 1.00 14.45 ? 576 PRO A CD 1 ATOM 4632 N N . PHE A 1 577 ? 57.032 86.688 -36.524 1.00 12.55 ? 577 PHE A N 1 ATOM 4633 C CA . PHE A 1 577 ? 57.934 86.137 -37.563 1.00 12.81 ? 577 PHE A CA 1 ATOM 4634 C C . PHE A 1 577 ? 58.912 85.203 -36.893 1.00 13.16 ? 577 PHE A C 1 ATOM 4635 O O . PHE A 1 577 ? 60.083 85.508 -36.665 1.00 13.75 ? 577 PHE A O 1 ATOM 4636 C CB . PHE A 1 577 ? 58.658 87.314 -38.277 1.00 14.18 ? 577 PHE A CB 1 ATOM 4637 C CG . PHE A 1 577 ? 57.696 88.330 -38.872 1.00 17.22 ? 577 PHE A CG 1 ATOM 4638 C CD1 . PHE A 1 577 ? 56.652 87.925 -39.671 1.00 16.68 ? 577 PHE A CD1 1 ATOM 4639 C CD2 . PHE A 1 577 ? 57.906 89.706 -38.669 1.00 19.70 ? 577 PHE A CD2 1 ATOM 4640 C CE1 . PHE A 1 577 ? 55.802 88.879 -40.303 1.00 18.46 ? 577 PHE A CE1 1 ATOM 4641 C CE2 . PHE A 1 577 ? 57.071 90.660 -39.290 1.00 20.73 ? 577 PHE A CE2 1 ATOM 4642 C CZ . PHE A 1 577 ? 56.034 90.234 -40.101 1.00 20.24 ? 577 PHE A CZ 1 ATOM 4643 N N . VAL A 1 578 ? 58.371 84.045 -36.522 1.00 12.41 ? 578 VAL A N 1 ATOM 4644 C CA . VAL A 1 578 ? 59.137 83.017 -35.812 1.00 12.29 ? 578 VAL A CA 1 ATOM 4645 C C . VAL A 1 578 ? 58.991 81.681 -36.513 1.00 11.99 ? 578 VAL A C 1 ATOM 4646 O O . VAL A 1 578 ? 57.912 81.338 -36.997 1.00 13.38 ? 578 VAL A O 1 ATOM 4647 C CB . VAL A 1 578 ? 58.611 82.912 -34.327 1.00 12.02 ? 578 VAL A CB 1 ATOM 4648 C CG1 . VAL A 1 578 ? 59.368 81.773 -33.578 1.00 12.45 ? 578 VAL A CG1 1 ATOM 4649 C CG2 . VAL A 1 578 ? 58.861 84.197 -33.615 1.00 12.49 ? 578 VAL A CG2 1 ATOM 4650 N N . SER A 1 579 ? 60.086 80.956 -36.584 1.00 12.97 ? 579 SER A N 1 ATOM 4651 C CA . SER A 1 579 ? 60.007 79.644 -37.186 1.00 14.58 ? 579 SER A CA 1 ATOM 4652 C C . SER A 1 579 ? 60.581 78.630 -36.232 1.00 12.55 ? 579 SER A C 1 ATOM 4653 O O . SER A 1 579 ? 61.352 78.963 -35.324 1.00 12.96 ? 579 SER A O 1 ATOM 4654 C CB . SER A 1 579 ? 60.609 79.618 -38.583 1.00 18.41 ? 579 SER A CB 1 ATOM 4655 O OG . SER A 1 579 ? 61.910 80.057 -38.519 1.00 20.19 ? 579 SER A OG 1 ATOM 4656 N N . VAL A 1 580 ? 60.191 77.393 -36.440 1.00 10.95 ? 580 VAL A N 1 ATOM 4657 C CA . VAL A 1 580 ? 60.580 76.309 -35.548 1.00 10.72 ? 580 VAL A CA 1 ATOM 4658 C C . VAL A 1 580 ? 61.442 75.272 -36.239 1.00 11.03 ? 580 VAL A C 1 ATOM 4659 O O . VAL A 1 580 ? 61.186 74.933 -37.422 1.00 12.09 ? 580 VAL A O 1 ATOM 4660 C CB . VAL A 1 580 ? 59.287 75.611 -35.033 1.00 10.83 ? 580 VAL A CB 1 ATOM 4661 C CG1 . VAL A 1 580 ? 59.642 74.563 -33.987 1.00 12.12 ? 580 VAL A CG1 1 ATOM 4662 C CG2 . VAL A 1 580 ? 58.314 76.644 -34.390 1.00 11.76 ? 580 VAL A CG2 1 ATOM 4663 N N . THR A 1 581 ? 62.423 74.771 -35.503 1.00 11.03 ? 581 THR A N 1 ATOM 4664 C CA . THR A 1 581 ? 63.277 73.701 -35.996 1.00 11.24 ? 581 THR A CA 1 ATOM 4665 C C . THR A 1 581 ? 63.450 72.676 -34.883 1.00 10.71 ? 581 THR A C 1 ATOM 4666 O O . THR A 1 581 ? 63.216 72.988 -33.688 1.00 11.19 ? 581 THR A O 1 ATOM 4667 C CB . THR A 1 581 ? 64.714 74.185 -36.377 1.00 12.38 ? 581 THR A CB 1 ATOM 4668 O OG1 . THR A 1 581 ? 65.211 75.108 -35.384 1.00 14.72 ? 581 THR A OG1 1 ATOM 4669 C CG2 . THR A 1 581 ? 64.688 74.926 -37.732 1.00 12.99 ? 581 THR A CG2 1 ATOM 4670 N N . ASP A 1 582 ? 63.782 71.450 -35.240 1.00 12.81 ? 582 ASP A N 1 ATOM 4671 C CA . ASP A 1 582 ? 64.076 70.404 -34.238 1.00 14.00 ? 582 ASP A CA 1 ATOM 4672 C C . ASP A 1 582 ? 65.588 70.500 -33.939 1.00 16.08 ? 582 ASP A C 1 ATOM 4673 O O . ASP A 1 582 ? 66.236 71.406 -34.469 1.00 15.66 ? 582 ASP A O 1 ATOM 4674 C CB . ASP A 1 582 ? 63.591 69.032 -34.697 1.00 16.39 ? 582 ASP A CB 1 ATOM 4675 C CG . ASP A 1 582 ? 64.341 68.492 -35.908 1.00 15.64 ? 582 ASP A CG 1 ATOM 4676 O OD1 . ASP A 1 582 ? 65.417 69.029 -36.272 1.00 14.79 ? 582 ASP A OD1 1 ATOM 4677 O OD2 . ASP A 1 582 ? 63.796 67.494 -36.438 1.00 17.35 ? 582 ASP A OD2 1 ATOM 4678 N N . LEU A 1 583 ? 66.186 69.646 -33.089 1.00 19.99 ? 583 LEU A N 1 ATOM 4679 C CA . LEU A 1 583 ? 67.610 69.961 -32.887 1.00 21.48 ? 583 LEU A CA 1 ATOM 4680 C C . LEU A 1 583 ? 68.525 69.458 -33.995 1.00 21.88 ? 583 LEU A C 1 ATOM 4681 O O . LEU A 1 583 ? 69.747 69.681 -33.924 1.00 24.59 ? 583 LEU A O 1 ATOM 4682 C CB . LEU A 1 583 ? 68.176 69.589 -31.478 1.00 21.76 ? 583 LEU A CB 1 ATOM 4683 C CG . LEU A 1 583 ? 69.132 70.620 -30.765 1.00 20.90 ? 583 LEU A CG 1 ATOM 4684 C CD1 . LEU A 1 583 ? 68.521 72.011 -30.749 1.00 23.86 ? 583 LEU A CD1 1 ATOM 4685 C CD2 . LEU A 1 583 ? 69.402 70.236 -29.317 1.00 22.99 ? 583 LEU A CD2 1 ATOM 4686 N N . ALA A 1 584 ? 67.963 68.805 -35.025 1.00 18.89 ? 584 ALA A N 1 ATOM 4687 C CA . ALA A 1 584 ? 68.827 68.501 -36.185 1.00 16.61 ? 584 ALA A CA 1 ATOM 4688 C C . ALA A 1 584 ? 68.624 69.646 -37.178 1.00 15.53 ? 584 ALA A C 1 ATOM 4689 O O . ALA A 1 584 ? 69.036 69.542 -38.347 1.00 14.38 ? 584 ALA A O 1 ATOM 4690 C CB . ALA A 1 584 ? 68.463 67.213 -36.844 1.00 15.80 ? 584 ALA A CB 1 ATOM 4691 N N . ASN A 1 585 ? 67.976 70.727 -36.752 1.00 15.10 ? 585 ASN A N 1 ATOM 4692 C CA . ASN A 1 585 ? 67.750 71.898 -37.615 1.00 15.85 ? 585 ASN A CA 1 ATOM 4693 C C . ASN A 1 585 ? 66.726 71.663 -38.735 1.00 15.61 ? 585 ASN A C 1 ATOM 4694 O O A ASN A 1 585 ? 66.605 72.432 -39.708 0.50 16.20 ? 585 ASN A O 1 ATOM 4695 O O B ASN A 1 585 ? 66.917 72.278 -39.766 0.50 15.82 ? 585 ASN A O 1 ATOM 4696 C CB . ASN A 1 585 ? 69.074 72.379 -38.224 1.00 18.18 ? 585 ASN A CB 1 ATOM 4697 C CG A ASN A 1 585 ? 69.307 73.830 -37.993 0.50 20.22 ? 585 ASN A CG 1 ATOM 4698 C CG B ASN A 1 585 ? 68.999 73.889 -38.494 0.50 17.58 ? 585 ASN A CG 1 ATOM 4699 O OD1 A ASN A 1 585 ? 68.383 74.643 -38.080 0.50 21.74 ? 585 ASN A OD1 1 ATOM 4700 O OD1 B ASN A 1 585 ? 68.450 74.728 -37.769 0.50 19.54 ? 585 ASN A OD1 1 ATOM 4701 N ND2 A ASN A 1 585 ? 70.550 74.182 -37.691 0.50 22.19 ? 585 ASN A ND2 1 ATOM 4702 N ND2 B ASN A 1 585 ? 69.543 74.201 -39.667 0.50 17.78 ? 585 ASN A ND2 1 ATOM 4703 N N . ASN A 1 586 ? 65.957 70.606 -38.598 1.00 13.99 ? 586 ASN A N 1 ATOM 4704 C CA . ASN A 1 586 ? 64.942 70.312 -39.621 1.00 14.93 ? 586 ASN A CA 1 ATOM 4705 C C . ASN A 1 586 ? 63.778 71.288 -39.371 1.00 14.93 ? 586 ASN A C 1 ATOM 4706 O O . ASN A 1 586 ? 63.316 71.455 -38.243 1.00 13.56 ? 586 ASN A O 1 ATOM 4707 C CB . ASN A 1 586 ? 64.357 68.904 -39.495 1.00 16.32 ? 586 ASN A CB 1 ATOM 4708 C CG . ASN A 1 586 ? 65.397 67.823 -39.610 1.00 16.18 ? 586 ASN A CG 1 ATOM 4709 O OD1 . ASN A 1 586 ? 66.282 67.891 -40.479 1.00 16.30 ? 586 ASN A OD1 1 ATOM 4710 N ND2 . ASN A 1 586 ? 65.317 66.810 -38.728 1.00 15.78 ? 586 ASN A ND2 1 ATOM 4711 N N . PRO A 1 587 ? 63.282 71.966 -40.397 1.00 14.51 ? 587 PRO A N 1 ATOM 4712 C CA . PRO A 1 587 ? 62.161 72.882 -40.167 1.00 14.62 ? 587 PRO A CA 1 ATOM 4713 C C . PRO A 1 587 ? 60.924 72.112 -39.743 1.00 13.64 ? 587 PRO A C 1 ATOM 4714 O O . PRO A 1 587 ? 60.694 70.968 -40.146 1.00 15.58 ? 587 PRO A O 1 ATOM 4715 C CB . PRO A 1 587 ? 61.959 73.579 -41.511 1.00 15.93 ? 587 PRO A CB 1 ATOM 4716 C CG . PRO A 1 587 ? 62.544 72.652 -42.485 1.00 18.90 ? 587 PRO A CG 1 ATOM 4717 C CD . PRO A 1 587 ? 63.729 71.979 -41.807 1.00 16.07 ? 587 PRO A CD 1 ATOM 4718 N N . VAL A 1 588 ? 60.102 72.740 -38.900 1.00 12.47 ? 588 VAL A N 1 ATOM 4719 C CA . VAL A 1 588 ? 58.892 72.127 -38.413 1.00 12.04 ? 588 VAL A CA 1 ATOM 4720 C C . VAL A 1 588 ? 57.779 73.125 -38.769 1.00 11.98 ? 588 VAL A C 1 ATOM 4721 O O . VAL A 1 588 ? 57.904 74.335 -38.496 1.00 12.69 ? 588 VAL A O 1 ATOM 4722 C CB . VAL A 1 588 ? 58.956 71.979 -36.855 1.00 11.98 ? 588 VAL A CB 1 ATOM 4723 C CG1 . VAL A 1 588 ? 57.651 71.498 -36.320 1.00 13.99 ? 588 VAL A CG1 1 ATOM 4724 C CG2 . VAL A 1 588 ? 60.136 71.042 -36.449 1.00 12.40 ? 588 VAL A CG2 1 ATOM 4725 N N . GLU A 1 589 ? 56.703 72.631 -39.367 1.00 12.28 ? 589 GLU A N 1 ATOM 4726 C CA . GLU A 1 589 ? 55.609 73.483 -39.769 1.00 12.83 ? 589 GLU A CA 1 ATOM 4727 C C . GLU A 1 589 ? 54.972 74.128 -38.552 1.00 12.51 ? 589 GLU A C 1 ATOM 4728 O O . GLU A 1 589 ? 54.742 73.436 -37.538 1.00 12.67 ? 589 GLU A O 1 ATOM 4729 C CB . GLU A 1 589 ? 54.559 72.657 -40.489 1.00 16.05 ? 589 GLU A CB 1 ATOM 4730 C CG . GLU A 1 589 ? 53.504 73.534 -41.043 1.00 22.34 ? 589 GLU A CG 1 ATOM 4731 C CD . GLU A 1 589 ? 52.370 72.806 -41.715 1.00 25.09 ? 589 GLU A CD 1 ATOM 4732 O OE1 . GLU A 1 589 ? 52.469 71.560 -41.883 1.00 27.50 ? 589 GLU A OE1 1 ATOM 4733 O OE2 . GLU A 1 589 ? 51.367 73.503 -42.081 1.00 27.61 ? 589 GLU A OE2 1 ATOM 4734 N N . ALA A 1 590 ? 54.664 75.417 -38.638 1.00 11.31 ? 590 ALA A N 1 ATOM 4735 C CA . ALA A 1 590 ? 54.080 76.103 -37.493 1.00 10.84 ? 590 ALA A CA 1 ATOM 4736 C C . ALA A 1 590 ? 52.991 77.045 -37.935 1.00 11.04 ? 590 ALA A C 1 ATOM 4737 O O . ALA A 1 590 ? 52.922 77.417 -39.111 1.00 12.07 ? 590 ALA A O 1 ATOM 4738 C CB . ALA A 1 590 ? 55.137 76.868 -36.768 1.00 11.46 ? 590 ALA A CB 1 ATOM 4739 N N . GLN A 1 591 ? 52.169 77.438 -36.995 1.00 10.08 ? 591 GLN A N 1 ATOM 4740 C CA . GLN A 1 591 ? 51.085 78.388 -37.235 1.00 9.96 ? 591 GLN A CA 1 ATOM 4741 C C . GLN A 1 591 ? 51.156 79.469 -36.170 1.00 10.74 ? 591 GLN A C 1 ATOM 4742 O O . GLN A 1 591 ? 51.392 79.180 -34.988 1.00 11.72 ? 591 GLN A O 1 ATOM 4743 C CB . GLN A 1 591 ? 49.702 77.689 -37.162 1.00 10.74 ? 591 GLN A CB 1 ATOM 4744 C CG . GLN A 1 591 ? 48.547 78.687 -37.142 1.00 11.80 ? 591 GLN A CG 1 ATOM 4745 C CD . GLN A 1 591 ? 47.220 77.978 -36.898 1.00 11.16 ? 591 GLN A CD 1 ATOM 4746 O OE1 . GLN A 1 591 ? 46.993 76.912 -37.464 1.00 12.15 ? 591 GLN A OE1 1 ATOM 4747 N NE2 . GLN A 1 591 ? 46.366 78.545 -36.092 1.00 11.75 ? 591 GLN A NE2 1 ATOM 4748 N N . VAL A 1 592 ? 50.978 80.726 -36.567 1.00 10.29 ? 592 VAL A N 1 ATOM 4749 C CA . VAL A 1 592 ? 50.962 81.812 -35.616 1.00 10.48 ? 592 VAL A CA 1 ATOM 4750 C C . VAL A 1 592 ? 49.560 82.376 -35.613 1.00 10.62 ? 592 VAL A C 1 ATOM 4751 O O . VAL A 1 592 ? 48.927 82.527 -36.671 1.00 10.84 ? 592 VAL A O 1 ATOM 4752 C CB . VAL A 1 592 ? 51.995 82.895 -35.980 1.00 11.43 ? 592 VAL A CB 1 ATOM 4753 C CG1 . VAL A 1 592 ? 51.771 84.171 -35.163 1.00 12.51 ? 592 VAL A CG1 1 ATOM 4754 C CG2 . VAL A 1 592 ? 53.402 82.369 -35.673 1.00 10.96 ? 592 VAL A CG2 1 ATOM 4755 N N . SER A 1 593 ? 49.042 82.664 -34.430 1.00 11.61 ? 593 SER A N 1 ATOM 4756 C CA . SER A 1 593 ? 47.708 83.241 -34.239 1.00 12.05 ? 593 SER A CA 1 ATOM 4757 C C . SER A 1 593 ? 47.863 84.357 -33.252 1.00 12.55 ? 593 SER A C 1 ATOM 4758 O O . SER A 1 593 ? 48.868 84.442 -32.510 1.00 13.76 ? 593 SER A O 1 ATOM 4759 C CB . SER A 1 593 ? 46.739 82.215 -33.583 1.00 13.04 ? 593 SER A CB 1 ATOM 4760 O OG . SER A 1 593 ? 46.535 81.057 -34.397 1.00 13.71 ? 593 SER A OG 1 ATOM 4761 N N . PRO A 1 594 ? 46.878 85.234 -33.164 1.00 12.00 ? 594 PRO A N 1 ATOM 4762 C CA . PRO A 1 594 ? 46.969 86.330 -32.188 1.00 11.32 ? 594 PRO A CA 1 ATOM 4763 C C . PRO A 1 594 ? 46.726 85.796 -30.764 1.00 11.80 ? 594 PRO A C 1 ATOM 4764 O O . PRO A 1 594 ? 46.298 84.635 -30.563 1.00 12.33 ? 594 PRO A O 1 ATOM 4765 C CB . PRO A 1 594 ? 45.801 87.268 -32.566 1.00 12.24 ? 594 PRO A CB 1 ATOM 4766 C CG . PRO A 1 594 ? 45.441 86.830 -34.014 1.00 12.15 ? 594 PRO A CG 1 ATOM 4767 C CD . PRO A 1 594 ? 45.677 85.363 -34.023 1.00 11.37 ? 594 PRO A CD 1 ATOM 4768 N N . VAL A 1 595 ? 47.000 86.650 -29.774 1.00 11.65 ? 595 VAL A N 1 ATOM 4769 C CA . VAL A 1 595 ? 46.673 86.331 -28.400 1.00 11.75 ? 595 VAL A CA 1 ATOM 4770 C C . VAL A 1 595 ? 45.408 87.140 -28.142 1.00 12.10 ? 595 VAL A C 1 ATOM 4771 O O . VAL A 1 595 ? 45.433 88.381 -28.131 1.00 13.00 ? 595 VAL A O 1 ATOM 4772 C CB . VAL A 1 595 ? 47.771 86.723 -27.407 1.00 12.34 ? 595 VAL A CB 1 ATOM 4773 C CG1 . VAL A 1 595 ? 47.261 86.464 -25.979 1.00 13.93 ? 595 VAL A CG1 1 ATOM 4774 C CG2 . VAL A 1 595 ? 49.004 85.846 -27.680 1.00 13.63 ? 595 VAL A CG2 1 ATOM 4775 N N . TRP A 1 596 ? 44.294 86.436 -27.969 1.00 11.94 ? 596 TRP A N 1 ATOM 4776 C CA . TRP A 1 596 ? 43.003 87.036 -27.732 1.00 12.93 ? 596 TRP A CA 1 ATOM 4777 C C . TRP A 1 596 ? 42.570 86.935 -26.286 1.00 14.27 ? 596 TRP A C 1 ATOM 4778 O O . TRP A 1 596 ? 42.667 85.858 -25.696 1.00 15.63 ? 596 TRP A O 1 ATOM 4779 C CB . TRP A 1 596 ? 41.929 86.328 -28.585 1.00 13.01 ? 596 TRP A CB 1 ATOM 4780 C CG . TRP A 1 596 ? 42.068 86.518 -30.056 1.00 12.14 ? 596 TRP A CG 1 ATOM 4781 C CD1 . TRP A 1 596 ? 42.470 85.585 -30.995 1.00 12.30 ? 596 TRP A CD1 1 ATOM 4782 C CD2 . TRP A 1 596 ? 41.760 87.703 -30.789 1.00 11.78 ? 596 TRP A CD2 1 ATOM 4783 N NE1 . TRP A 1 596 ? 42.417 86.133 -32.266 1.00 12.32 ? 596 TRP A NE1 1 ATOM 4784 C CE2 . TRP A 1 596 ? 41.994 87.427 -32.158 1.00 12.15 ? 596 TRP A CE2 1 ATOM 4785 C CE3 . TRP A 1 596 ? 41.309 88.991 -30.419 1.00 12.66 ? 596 TRP A CE3 1 ATOM 4786 C CZ2 . TRP A 1 596 ? 41.801 88.375 -33.148 1.00 13.43 ? 596 TRP A CZ2 1 ATOM 4787 C CZ3 . TRP A 1 596 ? 41.120 89.940 -31.437 1.00 14.11 ? 596 TRP A CZ3 1 ATOM 4788 C CH2 . TRP A 1 596 ? 41.364 89.619 -32.763 1.00 14.71 ? 596 TRP A CH2 1 ATOM 4789 N N . SER A 1 597 ? 42.121 88.032 -25.700 1.00 14.72 ? 597 SER A N 1 ATOM 4790 C CA . SER A 1 597 ? 41.603 87.985 -24.349 1.00 15.93 ? 597 SER A CA 1 ATOM 4791 C C . SER A 1 597 ? 40.203 88.591 -24.416 1.00 15.95 ? 597 SER A C 1 ATOM 4792 O O . SER A 1 597 ? 39.928 89.486 -25.230 1.00 18.16 ? 597 SER A O 1 ATOM 4793 C CB A SER A 1 597 ? 42.481 88.785 -23.391 0.50 15.72 ? 597 SER A CB 1 ATOM 4794 C CB B SER A 1 597 ? 42.515 89.171 -23.596 0.50 15.42 ? 597 SER A CB 1 ATOM 4795 O OG A SER A 1 597 ? 42.630 90.104 -23.857 0.50 15.98 ? 597 SER A OG 1 ATOM 4796 O OG B SER A 1 597 ? 43.892 88.840 -23.705 0.50 16.70 ? 597 SER A OG 1 ATOM 4797 N N . TRP A 1 598 ? 39.332 88.108 -23.556 1.00 15.78 ? 598 TRP A N 1 ATOM 4798 C CA . TRP A 1 598 ? 37.942 88.555 -23.528 1.00 15.69 ? 598 TRP A CA 1 ATOM 4799 C C . TRP A 1 598 ? 37.708 89.501 -22.362 1.00 18.49 ? 598 TRP A C 1 ATOM 4800 O O . TRP A 1 598 ? 38.180 89.263 -21.270 1.00 19.20 ? 598 TRP A O 1 ATOM 4801 C CB . TRP A 1 598 ? 37.008 87.337 -23.424 1.00 15.59 ? 598 TRP A CB 1 ATOM 4802 C CG . TRP A 1 598 ? 36.960 86.587 -24.709 1.00 13.03 ? 598 TRP A CG 1 ATOM 4803 C CD1 . TRP A 1 598 ? 37.866 85.684 -25.172 1.00 12.12 ? 598 TRP A CD1 1 ATOM 4804 C CD2 . TRP A 1 598 ? 35.952 86.694 -25.702 1.00 12.62 ? 598 TRP A CD2 1 ATOM 4805 N NE1 . TRP A 1 598 ? 37.500 85.224 -26.398 1.00 12.13 ? 598 TRP A NE1 1 ATOM 4806 C CE2 . TRP A 1 598 ? 36.314 85.808 -26.753 1.00 11.43 ? 598 TRP A CE2 1 ATOM 4807 C CE3 . TRP A 1 598 ? 34.768 87.439 -25.811 1.00 12.41 ? 598 TRP A CE3 1 ATOM 4808 C CZ2 . TRP A 1 598 ? 35.522 85.644 -27.903 1.00 12.04 ? 598 TRP A CZ2 1 ATOM 4809 C CZ3 . TRP A 1 598 ? 33.977 87.274 -26.959 1.00 12.17 ? 598 TRP A CZ3 1 ATOM 4810 C CH2 . TRP A 1 598 ? 34.365 86.374 -27.992 1.00 12.62 ? 598 TRP A CH2 1 ATOM 4811 N N . HIS A 1 599 ? 36.969 90.558 -22.614 1.00 21.03 ? 599 HIS A N 1 ATOM 4812 C CA . HIS A 1 599 ? 36.752 91.547 -21.589 1.00 24.77 ? 599 HIS A CA 1 ATOM 4813 C C . HIS A 1 599 ? 35.297 91.879 -21.479 1.00 26.14 ? 599 HIS A C 1 ATOM 4814 O O . HIS A 1 599 ? 34.597 91.954 -22.498 1.00 24.70 ? 599 HIS A O 1 ATOM 4815 C CB . HIS A 1 599 ? 37.525 92.816 -21.936 1.00 27.44 ? 599 HIS A CB 1 ATOM 4816 C CG . HIS A 1 599 ? 39.009 92.609 -22.000 1.00 30.37 ? 599 HIS A CG 1 ATOM 4817 N ND1 . HIS A 1 599 ? 39.760 92.241 -20.903 1.00 31.53 ? 599 HIS A ND1 1 ATOM 4818 C CD2 . HIS A 1 599 ? 39.863 92.613 -23.053 1.00 31.74 ? 599 HIS A CD2 1 ATOM 4819 C CE1 . HIS A 1 599 ? 41.006 92.015 -21.280 1.00 31.97 ? 599 HIS A CE1 1 ATOM 4820 N NE2 . HIS A 1 599 ? 41.095 92.232 -22.579 1.00 32.30 ? 599 HIS A NE2 1 ATOM 4821 N N . HIS A 1 600 ? 34.822 92.049 -20.248 1.00 29.26 ? 600 HIS A N 1 ATOM 4822 C CA . HIS A 1 600 ? 33.438 92.453 -20.095 1.00 32.61 ? 600 HIS A CA 1 ATOM 4823 C C . HIS A 1 600 ? 33.553 93.955 -20.071 1.00 33.25 ? 600 HIS A C 1 ATOM 4824 O O . HIS A 1 600 ? 34.003 94.524 -19.077 1.00 33.89 ? 600 HIS A O 1 ATOM 4825 C CB . HIS A 1 600 ? 32.781 92.003 -18.788 1.00 35.43 ? 600 HIS A CB 1 ATOM 4826 C CG . HIS A 1 600 ? 31.437 92.643 -18.579 1.00 38.55 ? 600 HIS A CG 1 ATOM 4827 N ND1 . HIS A 1 600 ? 30.442 92.599 -19.538 1.00 39.95 ? 600 HIS A ND1 1 ATOM 4828 C CD2 . HIS A 1 600 ? 30.962 93.436 -17.586 1.00 39.87 ? 600 HIS A CD2 1 ATOM 4829 C CE1 . HIS A 1 600 ? 29.418 93.338 -19.149 1.00 40.54 ? 600 HIS A CE1 1 ATOM 4830 N NE2 . HIS A 1 600 ? 29.707 93.859 -17.968 1.00 40.58 ? 600 HIS A NE2 1 ATOM 4831 N N . ASP A 1 601 ? 33.169 94.575 -21.179 1.00 34.01 ? 601 ASP A N 1 ATOM 4832 C CA . ASP A 1 601 ? 33.229 96.014 -21.359 1.00 35.29 ? 601 ASP A CA 1 ATOM 4833 C C . ASP A 1 601 ? 32.073 96.661 -20.578 1.00 36.02 ? 601 ASP A C 1 ATOM 4834 O O . ASP A 1 601 ? 30.923 96.525 -20.967 1.00 35.50 ? 601 ASP A O 1 ATOM 4835 C CB . ASP A 1 601 ? 33.088 96.314 -22.848 1.00 35.64 ? 601 ASP A CB 1 ATOM 4836 C CG . ASP A 1 601 ? 33.433 97.746 -23.200 1.00 36.61 ? 601 ASP A CG 1 ATOM 4837 O OD1 . ASP A 1 601 ? 33.235 98.647 -22.353 1.00 36.29 ? 601 ASP A OD1 1 ATOM 4838 O OD2 . ASP A 1 601 ? 33.884 97.979 -24.350 1.00 36.99 ? 601 ASP A OD2 1 ATOM 4839 N N . THR A 1 602 ? 32.365 97.347 -19.479 1.00 37.25 ? 602 THR A N 1 ATOM 4840 C CA . THR A 1 602 ? 31.287 97.987 -18.717 1.00 38.56 ? 602 THR A CA 1 ATOM 4841 C C . THR A 1 602 ? 30.749 99.204 -19.449 1.00 38.21 ? 602 THR A C 1 ATOM 4842 O O . THR A 1 602 ? 29.589 99.603 -19.243 1.00 39.17 ? 602 THR A O 1 ATOM 4843 C CB . THR A 1 602 ? 31.746 98.419 -17.324 1.00 39.65 ? 602 THR A CB 1 ATOM 4844 O OG1 . THR A 1 602 ? 32.926 99.231 -17.441 1.00 40.91 ? 602 THR A OG1 1 ATOM 4845 C CG2 . THR A 1 602 ? 32.013 97.190 -16.453 1.00 40.58 ? 602 THR A CG2 1 ATOM 4846 N N . LEU A 1 603 ? 31.561 99.792 -20.319 1.00 37.19 ? 603 LEU A N 1 ATOM 4847 C CA . LEU A 1 603 ? 31.086 100.944 -21.063 1.00 36.19 ? 603 LEU A CA 1 ATOM 4848 C C . LEU A 1 603 ? 30.000 100.559 -22.053 1.00 34.34 ? 603 LEU A C 1 ATOM 4849 O O . LEU A 1 603 ? 28.913 101.136 -22.049 1.00 35.02 ? 603 LEU A O 1 ATOM 4850 C CB . LEU A 1 603 ? 32.233 101.660 -21.800 1.00 37.78 ? 603 LEU A CB 1 ATOM 4851 C CG . LEU A 1 603 ? 33.220 102.458 -20.928 1.00 38.88 ? 603 LEU A CG 1 ATOM 4852 C CD1 . LEU A 1 603 ? 32.449 103.199 -19.811 1.00 39.69 ? 603 LEU A CD1 1 ATOM 4853 C CD2 . LEU A 1 603 ? 34.248 101.521 -20.312 1.00 39.81 ? 603 LEU A CD2 1 ATOM 4854 N N . THR A 1 604 ? 30.271 99.561 -22.883 1.00 31.04 ? 604 THR A N 1 ATOM 4855 C CA . THR A 1 604 ? 29.313 99.112 -23.886 1.00 27.90 ? 604 THR A CA 1 ATOM 4856 C C . THR A 1 604 ? 28.376 97.995 -23.397 1.00 25.02 ? 604 THR A C 1 ATOM 4857 O O . THR A 1 604 ? 27.409 97.670 -24.083 1.00 23.46 ? 604 THR A O 1 ATOM 4858 C CB . THR A 1 604 ? 30.045 98.593 -25.123 1.00 28.24 ? 604 THR A CB 1 ATOM 4859 O OG1 . THR A 1 604 ? 30.935 97.527 -24.723 1.00 28.57 ? 604 THR A OG1 1 ATOM 4860 C CG2 . THR A 1 604 ? 30.860 99.726 -25.773 1.00 28.98 ? 604 THR A CG2 1 ATOM 4861 N N . LYS A 1 605 ? 28.656 97.442 -22.221 1.00 23.25 ? 605 LYS A N 1 ATOM 4862 C CA . LYS A 1 605 ? 27.854 96.337 -21.660 1.00 22.27 ? 605 LYS A CA 1 ATOM 4863 C C . LYS A 1 605 ? 27.873 95.147 -22.609 1.00 21.91 ? 605 LYS A C 1 ATOM 4864 O O . LYS A 1 605 ? 26.841 94.579 -22.919 1.00 22.58 ? 605 LYS A O 1 ATOM 4865 C CB . LYS A 1 605 ? 26.387 96.743 -21.415 1.00 22.60 ? 605 LYS A CB 1 ATOM 4866 C CG . LYS A 1 605 ? 26.222 97.849 -20.419 1.00 23.88 ? 605 LYS A CG 1 ATOM 4867 C CD . LYS A 1 605 ? 26.777 97.446 -19.067 1.00 24.78 ? 605 LYS A CD 1 ATOM 4868 C CE . LYS A 1 605 ? 26.677 98.612 -18.066 1.00 26.06 ? 605 LYS A CE 1 ATOM 4869 N NZ . LYS A 1 605 ? 27.091 98.145 -16.725 1.00 28.55 ? 605 LYS A NZ 1 ATOM 4870 N N . THR A 1 606 ? 29.049 94.815 -23.121 1.00 20.19 ? 606 THR A N 1 ATOM 4871 C CA . THR A 1 606 ? 29.190 93.649 -24.015 1.00 19.60 ? 606 THR A CA 1 ATOM 4872 C C . THR A 1 606 ? 30.438 92.920 -23.590 1.00 19.13 ? 606 THR A C 1 ATOM 4873 O O . THR A 1 606 ? 31.313 93.482 -22.940 1.00 19.69 ? 606 THR A O 1 ATOM 4874 C CB . THR A 1 606 ? 29.428 94.046 -25.479 1.00 20.61 ? 606 THR A CB 1 ATOM 4875 O OG1 . THR A 1 606 ? 30.600 94.882 -25.552 1.00 23.02 ? 606 THR A OG1 1 ATOM 4876 C CG2 . THR A 1 606 ? 28.204 94.722 -26.060 1.00 21.28 ? 606 THR A CG2 1 ATOM 4877 N N . ILE A 1 607 ? 30.508 91.643 -23.955 1.00 17.65 ? 607 ILE A N 1 ATOM 4878 C CA . ILE A 1 607 ? 31.682 90.809 -23.696 1.00 16.51 ? 607 ILE A CA 1 ATOM 4879 C C . ILE A 1 607 ? 32.356 90.612 -25.070 1.00 15.85 ? 607 ILE A C 1 ATOM 4880 O O . ILE A 1 607 ? 31.782 90.030 -25.990 1.00 15.98 ? 607 ILE A O 1 ATOM 4881 C CB . ILE A 1 607 ? 31.237 89.497 -23.134 1.00 15.96 ? 607 ILE A CB 1 ATOM 4882 C CG1 . ILE A 1 607 ? 30.422 89.769 -21.863 1.00 17.53 ? 607 ILE A CG1 1 ATOM 4883 C CG2 . ILE A 1 607 ? 32.462 88.633 -22.814 1.00 17.34 ? 607 ILE A CG2 1 ATOM 4884 C CD1 . ILE A 1 607 ? 29.758 88.573 -21.275 1.00 19.66 ? 607 ILE A CD1 1 ATOM 4885 N N . HIS A 1 608 ? 33.594 91.088 -25.223 1.00 15.99 ? 608 HIS A N 1 ATOM 4886 C CA . HIS A 1 608 ? 34.204 90.998 -26.534 1.00 16.29 ? 608 HIS A CA 1 ATOM 4887 C C . HIS A 1 608 ? 35.701 90.795 -26.413 1.00 15.22 ? 608 HIS A C 1 ATOM 4888 O O . HIS A 1 608 ? 36.286 91.081 -25.373 1.00 16.96 ? 608 HIS A O 1 ATOM 4889 C CB . HIS A 1 608 ? 33.842 92.247 -27.366 1.00 20.07 ? 608 HIS A CB 1 ATOM 4890 C CG . HIS A 1 608 ? 34.427 93.515 -26.847 1.00 23.28 ? 608 HIS A CG 1 ATOM 4891 N ND1 . HIS A 1 608 ? 34.153 94.023 -25.594 1.00 26.33 ? 608 HIS A ND1 1 ATOM 4892 C CD2 . HIS A 1 608 ? 35.299 94.379 -27.419 1.00 26.06 ? 608 HIS A CD2 1 ATOM 4893 C CE1 . HIS A 1 608 ? 34.832 95.145 -25.413 1.00 26.61 ? 608 HIS A CE1 1 ATOM 4894 N NE2 . HIS A 1 608 ? 35.537 95.383 -26.506 1.00 27.02 ? 608 HIS A NE2 1 ATOM 4895 N N . PRO A 1 609 ? 36.338 90.346 -27.493 1.00 14.51 ? 609 PRO A N 1 ATOM 4896 C CA . PRO A 1 609 ? 37.771 90.069 -27.482 1.00 14.95 ? 609 PRO A CA 1 ATOM 4897 C C . PRO A 1 609 ? 38.662 91.213 -27.912 1.00 15.84 ? 609 PRO A C 1 ATOM 4898 O O . PRO A 1 609 ? 38.274 91.987 -28.791 1.00 17.86 ? 609 PRO A O 1 ATOM 4899 C CB . PRO A 1 609 ? 37.867 88.879 -28.453 1.00 14.86 ? 609 PRO A CB 1 ATOM 4900 C CG . PRO A 1 609 ? 36.865 89.267 -29.531 1.00 15.24 ? 609 PRO A CG 1 ATOM 4901 C CD . PRO A 1 609 ? 35.724 89.942 -28.777 1.00 14.20 ? 609 PRO A CD 1 ATOM 4902 N N . GLN A 1 610 ? 39.836 91.287 -27.286 1.00 16.04 ? 610 GLN A N 1 ATOM 4903 C CA . GLN A 1 610 ? 40.871 92.262 -27.605 1.00 17.28 ? 610 GLN A CA 1 ATOM 4904 C C . GLN A 1 610 ? 42.109 91.452 -27.971 1.00 15.24 ? 610 GLN A C 1 ATOM 4905 O O . GLN A 1 610 ? 42.388 90.446 -27.334 1.00 15.75 ? 610 GLN A O 1 ATOM 4906 C CB . GLN A 1 610 ? 41.165 93.143 -26.389 1.00 20.90 ? 610 GLN A CB 1 ATOM 4907 C CG . GLN A 1 610 ? 39.905 93.917 -25.947 1.00 27.10 ? 610 GLN A CG 1 ATOM 4908 C CD . GLN A 1 610 ? 39.568 95.128 -26.824 1.00 30.85 ? 610 GLN A CD 1 ATOM 4909 O OE1 . GLN A 1 610 ? 39.151 95.004 -28.003 1.00 32.69 ? 610 GLN A OE1 1 ATOM 4910 N NE2 . GLN A 1 610 ? 39.743 96.327 -26.236 1.00 32.93 ? 610 GLN A NE2 1 ATOM 4911 N N . GLY A 1 611 ? 42.796 91.868 -29.012 1.00 14.65 ? 611 GLY A N 1 ATOM 4912 C CA . GLY A 1 611 ? 43.995 91.153 -29.414 1.00 14.94 ? 611 GLY A CA 1 ATOM 4913 C C . GLY A 1 611 ? 45.224 91.895 -28.970 1.00 15.46 ? 611 GLY A C 1 ATOM 4914 O O . GLY A 1 611 ? 45.242 93.132 -28.905 1.00 15.75 ? 611 GLY A O 1 ATOM 4915 N N . SER A 1 612 ? 46.260 91.124 -28.657 1.00 15.02 ? 612 SER A N 1 ATOM 4916 C CA . SER A 1 612 ? 47.520 91.748 -28.257 1.00 15.54 ? 612 SER A CA 1 ATOM 4917 C C . SER A 1 612 ? 48.231 92.344 -29.441 1.00 15.64 ? 612 SER A C 1 ATOM 4918 O O . SER A 1 612 ? 48.189 91.815 -30.535 1.00 16.05 ? 612 SER A O 1 ATOM 4919 C CB . SER A 1 612 ? 48.445 90.703 -27.630 1.00 14.71 ? 612 SER A CB 1 ATOM 4920 O OG . SER A 1 612 ? 49.671 91.312 -27.294 1.00 16.72 ? 612 SER A OG 1 ATOM 4921 N N . THR A 1 613 ? 48.930 93.461 -29.219 1.00 18.67 ? 613 THR A N 1 ATOM 4922 C CA . THR A 1 613 ? 49.691 94.023 -30.310 1.00 18.86 ? 613 THR A CA 1 ATOM 4923 C C . THR A 1 613 ? 51.189 93.792 -30.048 1.00 19.68 ? 613 THR A C 1 ATOM 4924 O O . THR A 1 613 ? 52.028 94.261 -30.827 1.00 21.59 ? 613 THR A O 1 ATOM 4925 C CB . THR A 1 613 ? 49.450 95.511 -30.484 1.00 21.08 ? 613 THR A CB 1 ATOM 4926 O OG1 . THR A 1 613 ? 49.832 96.177 -29.283 1.00 21.29 ? 613 THR A OG1 1 ATOM 4927 C CG2 . THR A 1 613 ? 47.967 95.785 -30.741 1.00 20.16 ? 613 THR A CG2 1 ATOM 4928 N N . THR A 1 614 ? 51.510 93.063 -28.978 1.00 19.45 ? 614 THR A N 1 ATOM 4929 C CA . THR A 1 614 ? 52.920 92.791 -28.668 1.00 20.36 ? 614 THR A CA 1 ATOM 4930 C C . THR A 1 614 ? 53.320 91.316 -28.466 1.00 19.70 ? 614 THR A C 1 ATOM 4931 O O . THR A 1 614 ? 54.517 91.004 -28.338 1.00 19.69 ? 614 THR A O 1 ATOM 4932 C CB . THR A 1 614 ? 53.334 93.532 -27.430 1.00 21.49 ? 614 THR A CB 1 ATOM 4933 O OG1 . THR A 1 614 ? 52.474 93.182 -26.355 1.00 23.91 ? 614 THR A OG1 1 ATOM 4934 C CG2 . THR A 1 614 ? 53.351 95.057 -27.692 1.00 23.47 ? 614 THR A CG2 1 ATOM 4935 N N . LYS A 1 615 ? 52.350 90.411 -28.373 1.00 17.38 ? 615 LYS A N 1 ATOM 4936 C CA . LYS A 1 615 ? 52.680 89.004 -28.242 1.00 15.94 ? 615 LYS A CA 1 ATOM 4937 C C . LYS A 1 615 ? 51.725 88.210 -29.101 1.00 14.38 ? 615 LYS A C 1 ATOM 4938 O O . LYS A 1 615 ? 50.613 88.639 -29.383 1.00 14.27 ? 615 LYS A O 1 ATOM 4939 C CB . LYS A 1 615 ? 52.711 88.520 -26.793 1.00 18.16 ? 615 LYS A CB 1 ATOM 4940 C CG . LYS A 1 615 ? 51.408 88.504 -26.070 1.00 20.13 ? 615 LYS A CG 1 ATOM 4941 C CD . LYS A 1 615 ? 51.640 88.140 -24.577 1.00 23.00 ? 615 LYS A CD 1 ATOM 4942 C CE . LYS A 1 615 ? 50.340 87.898 -23.872 1.00 23.08 ? 615 LYS A CE 1 ATOM 4943 N NZ . LYS A 1 615 ? 50.542 88.046 -22.399 1.00 26.58 ? 615 LYS A NZ 1 ATOM 4944 N N . TYR A 1 616 ? 52.202 87.041 -29.523 1.00 11.88 ? 616 TYR A N 1 ATOM 4945 C CA . TYR A 1 616 ? 51.510 86.165 -30.440 1.00 12.09 ? 616 TYR A CA 1 ATOM 4946 C C . TYR A 1 616 ? 51.678 84.733 -30.021 1.00 11.35 ? 616 TYR A C 1 ATOM 4947 O O . TYR A 1 616 ? 52.584 84.413 -29.255 1.00 12.27 ? 616 TYR A O 1 ATOM 4948 C CB . TYR A 1 616 ? 52.146 86.381 -31.847 1.00 12.42 ? 616 TYR A CB 1 ATOM 4949 C CG . TYR A 1 616 ? 52.185 87.840 -32.216 1.00 14.99 ? 616 TYR A CG 1 ATOM 4950 C CD1 . TYR A 1 616 ? 51.043 88.438 -32.780 1.00 14.72 ? 616 TYR A CD1 1 ATOM 4951 C CD2 . TYR A 1 616 ? 53.285 88.640 -31.888 1.00 15.37 ? 616 TYR A CD2 1 ATOM 4952 C CE1 . TYR A 1 616 ? 50.985 89.776 -32.981 1.00 18.68 ? 616 TYR A CE1 1 ATOM 4953 C CE2 . TYR A 1 616 ? 53.247 90.023 -32.108 1.00 17.56 ? 616 TYR A CE2 1 ATOM 4954 C CZ . TYR A 1 616 ? 52.093 90.564 -32.642 1.00 18.10 ? 616 TYR A CZ 1 ATOM 4955 O OH . TYR A 1 616 ? 51.997 91.935 -32.861 1.00 23.08 ? 616 TYR A OH 1 ATOM 4956 N N . ARG A 1 617 ? 50.799 83.867 -30.499 1.00 11.29 ? 617 ARG A N 1 ATOM 4957 C CA . ARG A 1 617 ? 50.895 82.461 -30.172 1.00 12.10 ? 617 ARG A CA 1 ATOM 4958 C C . ARG A 1 617 ? 51.518 81.695 -31.330 1.00 12.12 ? 617 ARG A C 1 ATOM 4959 O O . ARG A 1 617 ? 51.021 81.841 -32.450 1.00 13.41 ? 617 ARG A O 1 ATOM 4960 C CB . ARG A 1 617 ? 49.509 81.862 -29.961 1.00 14.69 ? 617 ARG A CB 1 ATOM 4961 C CG . ARG A 1 617 ? 48.813 82.263 -28.707 1.00 17.94 ? 617 ARG A CG 1 ATOM 4962 C CD . ARG A 1 617 ? 47.416 81.555 -28.579 1.00 18.73 ? 617 ARG A CD 1 ATOM 4963 N NE . ARG A 1 617 ? 47.482 80.096 -28.631 1.00 18.46 ? 617 ARG A NE 1 ATOM 4964 C CZ . ARG A 1 617 ? 46.821 79.336 -29.510 1.00 19.94 ? 617 ARG A CZ 1 ATOM 4965 N NH1 . ARG A 1 617 ? 46.023 79.901 -30.428 1.00 18.60 ? 617 ARG A NH1 1 ATOM 4966 N NH2 . ARG A 1 617 ? 46.960 78.025 -29.501 1.00 19.54 ? 617 ARG A NH2 1 ATOM 4967 N N . ILE A 1 618 ? 52.555 80.883 -31.095 1.00 11.10 ? 618 ILE A N 1 ATOM 4968 C CA . ILE A 1 618 ? 53.107 80.018 -32.123 1.00 11.85 ? 618 ILE A CA 1 ATOM 4969 C C . ILE A 1 618 ? 52.737 78.608 -31.744 1.00 10.88 ? 618 ILE A C 1 ATOM 4970 O O . ILE A 1 618 ? 52.878 78.221 -30.596 1.00 11.37 ? 618 ILE A O 1 ATOM 4971 C CB . ILE A 1 618 ? 54.607 80.212 -32.369 1.00 11.86 ? 618 ILE A CB 1 ATOM 4972 C CG1 . ILE A 1 618 ? 54.978 79.407 -33.622 1.00 13.53 ? 618 ILE A CG1 1 ATOM 4973 C CG2 . ILE A 1 618 ? 55.455 79.878 -31.124 1.00 12.68 ? 618 ILE A CG2 1 ATOM 4974 C CD1 . ILE A 1 618 ? 56.231 79.836 -34.308 1.00 13.34 ? 618 ILE A CD1 1 ATOM 4975 N N . ILE A 1 619 ? 52.299 77.825 -32.710 1.00 10.96 ? 619 ILE A N 1 ATOM 4976 C CA . ILE A 1 619 ? 51.777 76.468 -32.501 1.00 10.46 ? 619 ILE A CA 1 ATOM 4977 C C . ILE A 1 619 ? 52.473 75.536 -33.466 1.00 10.03 ? 619 ILE A C 1 ATOM 4978 O O . ILE A 1 619 ? 52.663 75.863 -34.648 1.00 10.76 ? 619 ILE A O 1 ATOM 4979 C CB . ILE A 1 619 ? 50.268 76.463 -32.865 1.00 13.42 ? 619 ILE A CB 1 ATOM 4980 C CG1 . ILE A 1 619 ? 49.548 77.488 -32.003 1.00 15.14 ? 619 ILE A CG1 1 ATOM 4981 C CG2 . ILE A 1 619 ? 49.642 75.104 -32.795 1.00 16.03 ? 619 ILE A CG2 1 ATOM 4982 C CD1 . ILE A 1 619 ? 48.472 78.285 -32.849 1.00 15.94 ? 619 ILE A CD1 1 ATOM 4983 N N . PHE A 1 620 ? 52.872 74.372 -33.012 1.00 9.60 ? 620 PHE A N 1 ATOM 4984 C CA . PHE A 1 620 ? 53.533 73.401 -33.888 1.00 9.86 ? 620 PHE A CA 1 ATOM 4985 C C . PHE A 1 620 ? 53.412 72.029 -33.278 1.00 9.36 ? 620 PHE A C 1 ATOM 4986 O O . PHE A 1 620 ? 53.135 71.886 -32.080 1.00 9.96 ? 620 PHE A O 1 ATOM 4987 C CB . PHE A 1 620 ? 55.033 73.745 -34.109 1.00 9.33 ? 620 PHE A CB 1 ATOM 4988 C CG . PHE A 1 620 ? 55.877 73.685 -32.854 1.00 9.23 ? 620 PHE A CG 1 ATOM 4989 C CD1 . PHE A 1 620 ? 56.017 74.813 -32.044 1.00 10.16 ? 620 PHE A CD1 1 ATOM 4990 C CD2 . PHE A 1 620 ? 56.569 72.491 -32.526 1.00 10.58 ? 620 PHE A CD2 1 ATOM 4991 C CE1 . PHE A 1 620 ? 56.872 74.751 -30.889 1.00 10.71 ? 620 PHE A CE1 1 ATOM 4992 C CE2 . PHE A 1 620 ? 57.417 72.455 -31.369 1.00 9.81 ? 620 PHE A CE2 1 ATOM 4993 C CZ . PHE A 1 620 ? 57.544 73.585 -30.595 1.00 11.11 ? 620 PHE A CZ 1 ATOM 4994 N N . LYS A 1 621 ? 53.629 71.015 -34.090 1.00 9.87 ? 621 LYS A N 1 ATOM 4995 C CA . LYS A 1 621 ? 53.564 69.655 -33.583 1.00 11.47 ? 621 LYS A CA 1 ATOM 4996 C C . LYS A 1 621 ? 54.878 69.185 -32.989 1.00 11.14 ? 621 LYS A C 1 ATOM 4997 O O . LYS A 1 621 ? 55.916 69.207 -33.642 1.00 12.84 ? 621 LYS A O 1 ATOM 4998 C CB . LYS A 1 621 ? 53.140 68.718 -34.752 1.00 13.14 ? 621 LYS A CB 1 ATOM 4999 C CG . LYS A 1 621 ? 52.762 67.339 -34.276 1.00 17.66 ? 621 LYS A CG 1 ATOM 5000 C CD . LYS A 1 621 ? 51.802 66.641 -35.226 1.00 22.47 ? 621 LYS A CD 1 ATOM 5001 C CE . LYS A 1 621 ? 52.397 66.568 -36.608 1.00 24.15 ? 621 LYS A CE 1 ATOM 5002 N NZ . LYS A 1 621 ? 51.545 65.688 -37.519 1.00 26.72 ? 621 LYS A NZ 1 ATOM 5003 N N . ALA A 1 622 ? 54.829 68.801 -31.705 1.00 10.84 ? 622 ALA A N 1 ATOM 5004 C CA . ALA A 1 622 ? 55.985 68.230 -31.055 1.00 10.23 ? 622 ALA A CA 1 ATOM 5005 C C . ALA A 1 622 ? 55.885 66.701 -31.046 1.00 10.64 ? 622 ALA A C 1 ATOM 5006 O O . ALA A 1 622 ? 54.835 66.166 -30.754 1.00 12.67 ? 622 ALA A O 1 ATOM 5007 C CB . ALA A 1 622 ? 56.084 68.722 -29.585 1.00 11.09 ? 622 ALA A CB 1 ATOM 5008 N N . ARG A 1 623 ? 56.969 66.031 -31.416 1.00 9.54 ? 623 ARG A N 1 ATOM 5009 C CA . ARG A 1 623 ? 57.025 64.554 -31.399 1.00 10.24 ? 623 ARG A CA 1 ATOM 5010 C C . ARG A 1 623 ? 58.003 64.167 -30.309 1.00 8.88 ? 623 ARG A C 1 ATOM 5011 O O . ARG A 1 623 ? 59.171 64.551 -30.320 1.00 11.46 ? 623 ARG A O 1 ATOM 5012 C CB . ARG A 1 623 ? 57.464 64.068 -32.775 1.00 12.19 ? 623 ARG A CB 1 ATOM 5013 C CG . ARG A 1 623 ? 57.632 62.571 -32.848 1.00 13.62 ? 623 ARG A CG 1 ATOM 5014 C CD . ARG A 1 623 ? 57.887 62.084 -34.316 1.00 16.51 ? 623 ARG A CD 1 ATOM 5015 N NE . ARG A 1 623 ? 57.951 60.621 -34.292 1.00 21.02 ? 623 ARG A NE 1 ATOM 5016 C CZ . ARG A 1 623 ? 59.099 59.961 -34.161 1.00 21.75 ? 623 ARG A CZ 1 ATOM 5017 N NH1 . ARG A 1 623 ? 60.251 60.621 -34.075 1.00 24.55 ? 623 ARG A NH1 1 ATOM 5018 N NH2 . ARG A 1 623 ? 59.092 58.640 -34.026 1.00 23.96 ? 623 ARG A NH2 1 ATOM 5019 N N . VAL A 1 624 ? 57.476 63.452 -29.306 1.00 9.23 ? 624 VAL A N 1 ATOM 5020 C CA . VAL A 1 624 ? 58.228 63.175 -28.085 1.00 8.66 ? 624 VAL A CA 1 ATOM 5021 C C . VAL A 1 624 ? 58.261 61.687 -27.793 1.00 8.36 ? 624 VAL A C 1 ATOM 5022 O O . VAL A 1 624 ? 57.234 61.013 -27.869 1.00 8.99 ? 624 VAL A O 1 ATOM 5023 C CB . VAL A 1 624 ? 57.550 63.935 -26.914 1.00 9.48 ? 624 VAL A CB 1 ATOM 5024 C CG1 . VAL A 1 624 ? 58.467 63.963 -25.684 1.00 9.70 ? 624 VAL A CG1 1 ATOM 5025 C CG2 . VAL A 1 624 ? 57.210 65.390 -27.348 1.00 10.62 ? 624 VAL A CG2 1 ATOM 5026 N N . PRO A 1 625 ? 59.457 61.179 -27.424 1.00 8.70 ? 625 PRO A N 1 ATOM 5027 C CA . PRO A 1 625 ? 59.564 59.736 -27.142 1.00 9.41 ? 625 PRO A CA 1 ATOM 5028 C C . PRO A 1 625 ? 58.741 59.287 -25.925 1.00 9.05 ? 625 PRO A C 1 ATOM 5029 O O . PRO A 1 625 ? 58.333 60.105 -25.086 1.00 8.96 ? 625 PRO A O 1 ATOM 5030 C CB . PRO A 1 625 ? 61.063 59.501 -26.847 1.00 10.13 ? 625 PRO A CB 1 ATOM 5031 C CG . PRO A 1 625 ? 61.791 60.709 -27.423 1.00 10.53 ? 625 PRO A CG 1 ATOM 5032 C CD . PRO A 1 625 ? 60.754 61.861 -27.319 1.00 8.94 ? 625 PRO A CD 1 ATOM 5033 N N . PRO A 1 626 ? 58.522 57.990 -25.816 1.00 9.24 ? 626 PRO A N 1 ATOM 5034 C CA . PRO A 1 626 ? 57.780 57.435 -24.659 1.00 8.53 ? 626 PRO A CA 1 ATOM 5035 C C . PRO A 1 626 ? 58.575 57.854 -23.401 1.00 8.54 ? 626 PRO A C 1 ATOM 5036 O O . PRO A 1 626 ? 59.820 57.661 -23.328 1.00 8.70 ? 626 PRO A O 1 ATOM 5037 C CB . PRO A 1 626 ? 57.937 55.918 -24.839 1.00 8.41 ? 626 PRO A CB 1 ATOM 5038 C CG . PRO A 1 626 ? 58.189 55.742 -26.359 1.00 9.65 ? 626 PRO A CG 1 ATOM 5039 C CD . PRO A 1 626 ? 59.052 56.908 -26.707 1.00 10.78 ? 626 PRO A CD 1 ATOM 5040 N N . MET A 1 627 ? 57.899 58.412 -22.389 1.00 7.45 ? 627 MET A N 1 ATOM 5041 C CA . MET A 1 627 ? 58.537 58.825 -21.109 1.00 6.93 ? 627 MET A CA 1 ATOM 5042 C C . MET A 1 627 ? 59.828 59.604 -21.370 1.00 7.84 ? 627 MET A C 1 ATOM 5043 O O . MET A 1 627 ? 60.838 59.447 -20.704 1.00 8.54 ? 627 MET A O 1 ATOM 5044 C CB . MET A 1 627 ? 58.829 57.566 -20.258 1.00 7.88 ? 627 MET A CB 1 ATOM 5045 C CG . MET A 1 627 ? 57.550 56.883 -19.892 1.00 8.63 ? 627 MET A CG 1 ATOM 5046 S SD . MET A 1 627 ? 57.713 55.195 -19.179 1.00 10.79 ? 627 MET A SD 1 ATOM 5047 C CE . MET A 1 627 ? 58.583 55.572 -17.715 1.00 10.52 ? 627 MET A CE 1 ATOM 5048 N N . GLY A 1 628 ? 59.744 60.487 -22.372 1.00 7.90 ? 628 GLY A N 1 ATOM 5049 C CA . GLY A 1 628 ? 60.942 61.164 -22.812 1.00 8.47 ? 628 GLY A CA 1 ATOM 5050 C C . GLY A 1 628 ? 60.823 62.654 -23.051 1.00 7.70 ? 628 GLY A C 1 ATOM 5051 O O . GLY A 1 628 ? 59.848 63.304 -22.643 1.00 7.86 ? 628 GLY A O 1 ATOM 5052 N N . LEU A 1 629 ? 61.875 63.183 -23.688 1.00 8.28 ? 629 LEU A N 1 ATOM 5053 C CA . LEU A 1 629 ? 62.006 64.616 -23.930 1.00 8.57 ? 629 LEU A CA 1 ATOM 5054 C C . LEU A 1 629 ? 62.445 64.915 -25.336 1.00 8.74 ? 629 LEU A C 1 ATOM 5055 O O . LEU A 1 629 ? 63.204 64.142 -25.956 1.00 9.48 ? 629 LEU A O 1 ATOM 5056 C CB . LEU A 1 629 ? 63.078 65.217 -23.031 1.00 8.67 ? 629 LEU A CB 1 ATOM 5057 C CG . LEU A 1 629 ? 62.853 65.052 -21.526 1.00 8.51 ? 629 LEU A CG 1 ATOM 5058 C CD1 . LEU A 1 629 ? 64.146 65.343 -20.749 1.00 8.86 ? 629 LEU A CD1 1 ATOM 5059 C CD2 . LEU A 1 629 ? 61.755 66.052 -21.075 1.00 9.30 ? 629 LEU A CD2 1 ATOM 5060 N N . ALA A 1 630 ? 61.950 66.029 -25.847 1.00 7.82 ? 630 ALA A N 1 ATOM 5061 C CA . ALA A 1 630 ? 62.354 66.471 -27.205 1.00 9.39 ? 630 ALA A CA 1 ATOM 5062 C C . ALA A 1 630 ? 62.581 67.960 -27.188 1.00 9.10 ? 630 ALA A C 1 ATOM 5063 O O . ALA A 1 630 ? 61.748 68.736 -26.663 1.00 9.66 ? 630 ALA A O 1 ATOM 5064 C CB . ALA A 1 630 ? 61.284 66.119 -28.237 1.00 10.65 ? 630 ALA A CB 1 ATOM 5065 N N . THR A 1 631 ? 63.668 68.389 -27.849 1.00 9.04 ? 631 THR A N 1 ATOM 5066 C CA . THR A 1 631 ? 64.052 69.812 -27.888 1.00 10.15 ? 631 THR A CA 1 ATOM 5067 C C . THR A 1 631 ? 63.766 70.455 -29.222 1.00 9.96 ? 631 THR A C 1 ATOM 5068 O O . THR A 1 631 ? 64.014 69.843 -30.279 1.00 10.37 ? 631 THR A O 1 ATOM 5069 C CB . THR A 1 631 ? 65.553 69.918 -27.626 1.00 9.69 ? 631 THR A CB 1 ATOM 5070 O OG1 . THR A 1 631 ? 65.841 69.257 -26.363 1.00 10.67 ? 631 THR A OG1 1 ATOM 5071 C CG2 . THR A 1 631 ? 66.011 71.387 -27.501 1.00 11.39 ? 631 THR A CG2 1 ATOM 5072 N N . TYR A 1 632 ? 63.250 71.675 -29.182 1.00 9.19 ? 632 TYR A N 1 ATOM 5073 C CA . TYR A 1 632 ? 63.012 72.474 -30.381 1.00 9.09 ? 632 TYR A CA 1 ATOM 5074 C C . TYR A 1 632 ? 63.595 73.853 -30.192 1.00 9.35 ? 632 TYR A C 1 ATOM 5075 O O . TYR A 1 632 ? 63.886 74.294 -29.083 1.00 10.37 ? 632 TYR A O 1 ATOM 5076 C CB . TYR A 1 632 ? 61.512 72.561 -30.700 1.00 9.95 ? 632 TYR A CB 1 ATOM 5077 C CG . TYR A 1 632 ? 60.904 71.248 -31.108 1.00 9.33 ? 632 TYR A CG 1 ATOM 5078 C CD1 . TYR A 1 632 ? 60.547 70.317 -30.148 1.00 10.85 ? 632 TYR A CD1 1 ATOM 5079 C CD2 . TYR A 1 632 ? 60.705 70.938 -32.463 1.00 11.42 ? 632 TYR A CD2 1 ATOM 5080 C CE1 . TYR A 1 632 ? 59.997 69.080 -30.532 1.00 11.62 ? 632 TYR A CE1 1 ATOM 5081 C CE2 . TYR A 1 632 ? 60.161 69.714 -32.866 1.00 12.41 ? 632 TYR A CE2 1 ATOM 5082 C CZ . TYR A 1 632 ? 59.816 68.799 -31.886 1.00 11.11 ? 632 TYR A CZ 1 ATOM 5083 O OH . TYR A 1 632 ? 59.314 67.577 -32.256 1.00 13.82 ? 632 TYR A OH 1 ATOM 5084 N N . VAL A 1 633 ? 63.761 74.569 -31.313 1.00 9.68 ? 633 VAL A N 1 ATOM 5085 C CA . VAL A 1 633 ? 64.307 75.913 -31.292 1.00 10.61 ? 633 VAL A CA 1 ATOM 5086 C C . VAL A 1 633 ? 63.362 76.871 -32.021 1.00 9.93 ? 633 VAL A C 1 ATOM 5087 O O . VAL A 1 633 ? 62.860 76.548 -33.096 1.00 10.21 ? 633 VAL A O 1 ATOM 5088 C CB . VAL A 1 633 ? 65.685 75.972 -31.998 1.00 11.14 ? 633 VAL A CB 1 ATOM 5089 C CG1 . VAL A 1 633 ? 66.269 77.420 -31.946 1.00 13.32 ? 633 VAL A CG1 1 ATOM 5090 C CG2 . VAL A 1 633 ? 66.624 74.957 -31.348 1.00 14.01 ? 633 VAL A CG2 1 ATOM 5091 N N . LEU A 1 634 ? 63.087 78.023 -31.402 1.00 9.72 ? 634 LEU A N 1 ATOM 5092 C CA . LEU A 1 634 ? 62.232 79.071 -31.997 1.00 10.45 ? 634 LEU A CA 1 ATOM 5093 C C . LEU A 1 634 ? 63.184 80.195 -32.401 1.00 10.82 ? 634 LEU A C 1 ATOM 5094 O O . LEU A 1 634 ? 63.959 80.681 -31.574 1.00 10.48 ? 634 LEU A O 1 ATOM 5095 C CB . LEU A 1 634 ? 61.207 79.617 -30.985 1.00 11.43 ? 634 LEU A CB 1 ATOM 5096 C CG . LEU A 1 634 ? 60.300 78.587 -30.272 1.00 17.26 ? 634 LEU A CG 1 ATOM 5097 C CD1 . LEU A 1 634 ? 59.048 79.317 -29.739 1.00 16.60 ? 634 LEU A CD1 1 ATOM 5098 C CD2 . LEU A 1 634 ? 59.968 77.400 -31.067 1.00 19.05 ? 634 LEU A CD2 1 ATOM 5099 N N . THR A 1 635 ? 63.117 80.619 -33.682 1.00 10.28 ? 635 THR A N 1 ATOM 5100 C CA . THR A 1 635 ? 64.038 81.643 -34.174 1.00 10.47 ? 635 THR A CA 1 ATOM 5101 C C . THR A 1 635 ? 63.256 82.783 -34.842 1.00 11.27 ? 635 THR A C 1 ATOM 5102 O O . THR A 1 635 ? 62.347 82.561 -35.635 1.00 11.77 ? 635 THR A O 1 ATOM 5103 C CB . THR A 1 635 ? 64.965 80.986 -35.222 1.00 12.33 ? 635 THR A CB 1 ATOM 5104 O OG1 . THR A 1 635 ? 65.683 79.880 -34.620 1.00 12.25 ? 635 THR A OG1 1 ATOM 5105 C CG2 . THR A 1 635 ? 66.029 82.022 -35.718 1.00 12.35 ? 635 THR A CG2 1 ATOM 5106 N N . ILE A 1 636 ? 63.677 84.015 -34.559 1.00 11.81 ? 636 ILE A N 1 ATOM 5107 C CA . ILE A 1 636 ? 62.976 85.167 -35.159 1.00 12.27 ? 636 ILE A CA 1 ATOM 5108 C C . ILE A 1 636 ? 63.598 85.497 -36.518 1.00 13.86 ? 636 ILE A C 1 ATOM 5109 O O . ILE A 1 636 ? 64.777 85.195 -36.769 1.00 14.81 ? 636 ILE A O 1 ATOM 5110 C CB . ILE A 1 636 ? 63.070 86.416 -34.223 1.00 12.18 ? 636 ILE A CB 1 ATOM 5111 C CG1 . ILE A 1 636 ? 62.109 87.500 -34.699 1.00 13.39 ? 636 ILE A CG1 1 ATOM 5112 C CG2 . ILE A 1 636 ? 64.508 86.956 -34.149 1.00 14.61 ? 636 ILE A CG2 1 ATOM 5113 C CD1 . ILE A 1 636 ? 62.048 88.677 -33.733 1.00 15.43 ? 636 ILE A CD1 1 ATOM 5114 N N . SER A 1 637 ? 62.783 86.067 -37.395 1.00 15.66 ? 637 SER A N 1 ATOM 5115 C CA . SER A 1 637 ? 63.311 86.528 -38.687 1.00 18.97 ? 637 SER A CA 1 ATOM 5116 C C . SER A 1 637 ? 62.670 87.891 -38.961 1.00 20.31 ? 637 SER A C 1 ATOM 5117 O O . SER A 1 637 ? 61.770 88.313 -38.252 1.00 19.30 ? 637 SER A O 1 ATOM 5118 C CB . SER A 1 637 ? 63.042 85.506 -39.814 1.00 21.27 ? 637 SER A CB 1 ATOM 5119 O OG . SER A 1 637 ? 61.663 85.304 -39.960 1.00 24.47 ? 637 SER A OG 1 ATOM 5120 N N . ASP A 1 638 ? 63.172 88.616 -39.964 1.00 23.23 ? 638 ASP A N 1 ATOM 5121 C CA . ASP A 1 638 ? 62.623 89.954 -40.232 1.00 26.07 ? 638 ASP A CA 1 ATOM 5122 C C . ASP A 1 638 ? 61.225 89.931 -40.871 1.00 25.76 ? 638 ASP A C 1 ATOM 5123 O O . ASP A 1 638 ? 60.416 90.872 -40.693 1.00 27.37 ? 638 ASP A O 1 ATOM 5124 C CB . ASP A 1 638 ? 63.573 90.740 -41.138 1.00 29.32 ? 638 ASP A CB 1 ATOM 5125 C CG . ASP A 1 638 ? 63.546 90.228 -42.564 1.00 32.74 ? 638 ASP A CG 1 ATOM 5126 O OD1 . ASP A 1 638 ? 63.972 89.063 -42.801 1.00 35.54 ? 638 ASP A OD1 1 ATOM 5127 O OD2 . ASP A 1 638 ? 63.068 90.983 -43.457 1.00 36.94 ? 638 ASP A OD2 1 ATOM 5128 N N . SER A 1 639 ? 60.930 88.841 -41.571 1.00 24.74 ? 639 SER A N 1 ATOM 5129 C CA . SER A 1 639 ? 59.667 88.691 -42.272 1.00 24.14 ? 639 SER A CA 1 ATOM 5130 C C . SER A 1 639 ? 59.107 87.284 -42.192 1.00 22.96 ? 639 SER A C 1 ATOM 5131 O O . SER A 1 639 ? 59.714 86.399 -41.586 1.00 20.66 ? 639 SER A O 1 ATOM 5132 C CB . SER A 1 639 ? 59.848 89.069 -43.753 1.00 24.29 ? 639 SER A CB 1 ATOM 5133 O OG . SER A 1 639 ? 60.841 88.252 -44.333 1.00 26.31 ? 639 SER A OG 1 ATOM 5134 N N . LYS A 1 640 ? 57.952 87.083 -42.814 1.00 22.05 ? 640 LYS A N 1 ATOM 5135 C CA . LYS A 1 640 ? 57.303 85.775 -42.785 1.00 22.39 ? 640 LYS A CA 1 ATOM 5136 C C . LYS A 1 640 ? 58.241 84.647 -43.180 1.00 21.64 ? 640 LYS A C 1 ATOM 5137 O O . LYS A 1 640 ? 58.800 84.646 -44.278 1.00 22.28 ? 640 LYS A O 1 ATOM 5138 C CB . LYS A 1 640 ? 56.075 85.759 -43.703 1.00 23.80 ? 640 LYS A CB 1 ATOM 5139 C CG . LYS A 1 640 ? 54.965 86.765 -43.353 1.00 28.09 ? 640 LYS A CG 1 ATOM 5140 C CD . LYS A 1 640 ? 53.639 86.475 -44.114 1.00 30.30 ? 640 LYS A CD 1 ATOM 5141 C CE . LYS A 1 640 ? 53.787 86.413 -45.636 1.00 32.83 ? 640 LYS A CE 1 ATOM 5142 N NZ . LYS A 1 640 ? 54.030 87.736 -46.301 1.00 34.34 ? 640 LYS A NZ 1 ATOM 5143 N N . PRO A 1 641 ? 58.476 83.684 -42.273 1.00 19.52 ? 641 PRO A N 1 ATOM 5144 C CA . PRO A 1 641 ? 59.355 82.562 -42.598 1.00 18.99 ? 641 PRO A CA 1 ATOM 5145 C C . PRO A 1 641 ? 58.610 81.540 -43.452 1.00 18.15 ? 641 PRO A C 1 ATOM 5146 O O . PRO A 1 641 ? 57.374 81.439 -43.428 1.00 17.50 ? 641 PRO A O 1 ATOM 5147 C CB . PRO A 1 641 ? 59.740 81.980 -41.243 1.00 20.56 ? 641 PRO A CB 1 ATOM 5148 C CG . PRO A 1 641 ? 58.687 82.404 -40.375 1.00 19.66 ? 641 PRO A CG 1 ATOM 5149 C CD . PRO A 1 641 ? 58.210 83.748 -40.823 1.00 19.69 ? 641 PRO A CD 1 ATOM 5150 N N . GLU A 1 642 ? 59.384 80.753 -44.177 1.00 18.61 ? 642 GLU A N 1 ATOM 5151 C CA . GLU A 1 642 ? 58.823 79.777 -45.090 1.00 19.51 ? 642 GLU A CA 1 ATOM 5152 C C . GLU A 1 642 ? 57.897 78.719 -44.521 1.00 19.04 ? 642 GLU A C 1 ATOM 5153 O O . GLU A 1 642 ? 56.899 78.347 -45.124 1.00 20.08 ? 642 GLU A O 1 ATOM 5154 C CB . GLU A 1 642 ? 59.983 79.088 -45.845 1.00 21.64 ? 642 GLU A CB 1 ATOM 5155 C CG . GLU A 1 642 ? 59.559 77.942 -46.737 1.00 25.98 ? 642 GLU A CG 1 ATOM 5156 C CD . GLU A 1 642 ? 60.736 77.270 -47.474 1.00 28.46 ? 642 GLU A CD 1 ATOM 5157 O OE1 . GLU A 1 642 ? 61.893 77.776 -47.390 1.00 30.84 ? 642 GLU A OE1 1 ATOM 5158 O OE2 . GLU A 1 642 ? 60.482 76.228 -48.129 1.00 30.59 ? 642 GLU A OE2 1 ATOM 5159 N N . HIS A 1 643 ? 58.192 78.274 -43.308 1.00 17.32 ? 643 HIS A N 1 ATOM 5160 C CA . HIS A 1 643 ? 57.419 77.175 -42.730 1.00 16.01 ? 643 HIS A CA 1 ATOM 5161 C C . HIS A 1 643 ? 56.420 77.577 -41.649 1.00 14.72 ? 643 HIS A C 1 ATOM 5162 O O . HIS A 1 643 ? 55.974 76.709 -40.884 1.00 14.73 ? 643 HIS A O 1 ATOM 5163 C CB . HIS A 1 643 ? 58.384 76.142 -42.187 1.00 16.78 ? 643 HIS A CB 1 ATOM 5164 C CG . HIS A 1 643 ? 59.255 75.560 -43.255 1.00 18.04 ? 643 HIS A CG 1 ATOM 5165 N ND1 . HIS A 1 643 ? 58.824 74.554 -44.080 1.00 20.93 ? 643 HIS A ND1 1 ATOM 5166 C CD2 . HIS A 1 643 ? 60.508 75.875 -43.657 1.00 18.18 ? 643 HIS A CD2 1 ATOM 5167 C CE1 . HIS A 1 643 ? 59.780 74.261 -44.951 1.00 19.13 ? 643 HIS A CE1 1 ATOM 5168 N NE2 . HIS A 1 643 ? 60.812 75.048 -44.712 1.00 19.84 ? 643 HIS A NE2 1 ATOM 5169 N N . THR A 1 644 ? 56.105 78.861 -41.589 1.00 13.24 ? 644 THR A N 1 ATOM 5170 C CA . THR A 1 644 ? 55.132 79.359 -40.634 1.00 12.77 ? 644 THR A CA 1 ATOM 5171 C C . THR A 1 644 ? 53.986 80.019 -41.389 1.00 13.30 ? 644 THR A C 1 ATOM 5172 O O . THR A 1 644 ? 54.253 80.836 -42.292 1.00 14.21 ? 644 THR A O 1 ATOM 5173 C CB . THR A 1 644 ? 55.785 80.387 -39.693 1.00 12.77 ? 644 THR A CB 1 ATOM 5174 O OG1 . THR A 1 644 ? 56.821 79.707 -38.961 1.00 12.97 ? 644 THR A OG1 1 ATOM 5175 C CG2 . THR A 1 644 ? 54.743 80.976 -38.643 1.00 13.26 ? 644 THR A CG2 1 ATOM 5176 N N . SER A 1 645 ? 52.755 79.641 -41.047 1.00 12.39 ? 645 SER A N 1 ATOM 5177 C CA . SER A 1 645 ? 51.551 80.209 -41.657 1.00 12.88 ? 645 SER A CA 1 ATOM 5178 C C . SER A 1 645 ? 50.851 81.024 -40.597 1.00 12.09 ? 645 SER A C 1 ATOM 5179 O O . SER A 1 645 ? 51.186 80.944 -39.407 1.00 12.26 ? 645 SER A O 1 ATOM 5180 C CB . SER A 1 645 ? 50.605 79.113 -42.163 1.00 13.50 ? 645 SER A CB 1 ATOM 5181 O OG . SER A 1 645 ? 50.145 78.300 -41.057 1.00 15.21 ? 645 SER A OG 1 ATOM 5182 N N . TYR A 1 646 ? 49.887 81.836 -41.007 1.00 11.56 ? 646 TYR A N 1 ATOM 5183 C CA . TYR A 1 646 ? 49.164 82.743 -40.127 1.00 11.86 ? 646 TYR A CA 1 ATOM 5184 C C . TYR A 1 646 ? 47.669 82.538 -40.208 1.00 11.96 ? 646 TYR A C 1 ATOM 5185 O O . TYR A 1 646 ? 47.110 82.428 -41.285 1.00 13.39 ? 646 TYR A O 1 ATOM 5186 C CB . TYR A 1 646 ? 49.506 84.191 -40.518 1.00 13.40 ? 646 TYR A CB 1 ATOM 5187 C CG . TYR A 1 646 ? 50.961 84.459 -40.320 1.00 12.01 ? 646 TYR A CG 1 ATOM 5188 C CD1 . TYR A 1 646 ? 51.423 84.854 -39.068 1.00 12.04 ? 646 TYR A CD1 1 ATOM 5189 C CD2 . TYR A 1 646 ? 51.899 84.165 -41.328 1.00 13.18 ? 646 TYR A CD2 1 ATOM 5190 C CE1 . TYR A 1 646 ? 52.769 84.944 -38.825 1.00 13.10 ? 646 TYR A CE1 1 ATOM 5191 C CE2 . TYR A 1 646 ? 53.282 84.255 -41.073 1.00 15.11 ? 646 TYR A CE2 1 ATOM 5192 C CZ . TYR A 1 646 ? 53.687 84.644 -39.811 1.00 13.23 ? 646 TYR A CZ 1 ATOM 5193 O OH . TYR A 1 646 ? 55.041 84.711 -39.512 1.00 15.35 ? 646 TYR A OH 1 ATOM 5194 N N . ALA A 1 647 ? 47.013 82.407 -39.057 1.00 10.95 ? 647 ALA A N 1 ATOM 5195 C CA . ALA A 1 647 ? 45.596 82.210 -39.034 1.00 10.37 ? 647 ALA A CA 1 ATOM 5196 C C . ALA A 1 647 ? 44.820 83.436 -39.469 1.00 11.25 ? 647 ALA A C 1 ATOM 5197 O O . ALA A 1 647 ? 45.256 84.588 -39.323 1.00 11.77 ? 647 ALA A O 1 ATOM 5198 C CB . ALA A 1 647 ? 45.152 81.837 -37.614 1.00 12.21 ? 647 ALA A CB 1 ATOM 5199 N N . SER A 1 648 ? 43.677 83.181 -40.068 1.00 11.02 ? 648 SER A N 1 ATOM 5200 C CA . SER A 1 648 ? 42.795 84.296 -40.353 1.00 11.68 ? 648 SER A CA 1 ATOM 5201 C C . SER A 1 648 ? 41.908 84.488 -39.102 1.00 11.17 ? 648 SER A C 1 ATOM 5202 O O . SER A 1 648 ? 41.723 83.551 -38.274 1.00 11.23 ? 648 SER A O 1 ATOM 5203 C CB . SER A 1 648 ? 41.920 83.986 -41.572 1.00 12.88 ? 648 SER A CB 1 ATOM 5204 O OG . SER A 1 648 ? 41.105 82.857 -41.369 1.00 17.94 ? 648 SER A OG 1 ATOM 5205 N N . ASN A 1 649 ? 41.280 85.648 -38.953 1.00 10.21 ? 649 ASN A N 1 ATOM 5206 C CA . ASN A 1 649 ? 40.445 85.929 -37.789 1.00 10.81 ? 649 ASN A CA 1 ATOM 5207 C C . ASN A 1 649 ? 39.227 86.678 -38.260 1.00 10.85 ? 649 ASN A C 1 ATOM 5208 O O . ASN A 1 649 ? 39.369 87.647 -39.035 1.00 12.49 ? 649 ASN A O 1 ATOM 5209 C CB . ASN A 1 649 ? 41.219 86.753 -36.744 1.00 10.62 ? 649 ASN A CB 1 ATOM 5210 C CG . ASN A 1 649 ? 42.395 85.980 -36.166 1.00 11.41 ? 649 ASN A CG 1 ATOM 5211 O OD1 . ASN A 1 649 ? 42.240 85.196 -35.187 1.00 11.33 ? 649 ASN A OD1 1 ATOM 5212 N ND2 . ASN A 1 649 ? 43.568 86.137 -36.765 1.00 11.50 ? 649 ASN A ND2 1 ATOM 5213 N N . LEU A 1 650 ? 38.065 86.233 -37.817 1.00 11.01 ? 650 LEU A N 1 ATOM 5214 C CA . LEU A 1 650 ? 36.785 86.840 -38.229 1.00 10.94 ? 650 LEU A CA 1 ATOM 5215 C C . LEU A 1 650 ? 35.967 87.108 -36.974 1.00 11.03 ? 650 LEU A C 1 ATOM 5216 O O . LEU A 1 650 ? 35.667 86.173 -36.190 1.00 12.25 ? 650 LEU A O 1 ATOM 5217 C CB . LEU A 1 650 ? 36.044 85.877 -39.144 1.00 12.44 ? 650 LEU A CB 1 ATOM 5218 C CG . LEU A 1 650 ? 34.571 86.202 -39.434 1.00 12.32 ? 650 LEU A CG 1 ATOM 5219 C CD1 . LEU A 1 650 ? 34.531 87.515 -40.321 1.00 14.40 ? 650 LEU A CD1 1 ATOM 5220 C CD2 . LEU A 1 650 ? 33.966 85.055 -40.255 1.00 14.88 ? 650 LEU A CD2 1 ATOM 5221 N N . LEU A 1 651 ? 35.615 88.356 -36.731 1.00 12.31 ? 651 LEU A N 1 ATOM 5222 C CA . LEU A 1 651 ? 34.837 88.786 -35.580 1.00 13.18 ? 651 LEU A CA 1 ATOM 5223 C C . LEU A 1 651 ? 33.402 89.015 -36.037 1.00 14.15 ? 651 LEU A C 1 ATOM 5224 O O . LEU A 1 651 ? 33.155 89.845 -36.912 1.00 14.50 ? 651 LEU A O 1 ATOM 5225 C CB . LEU A 1 651 ? 35.441 90.059 -35.006 1.00 16.07 ? 651 LEU A CB 1 ATOM 5226 C CG . LEU A 1 651 ? 35.097 90.492 -33.570 1.00 19.82 ? 651 LEU A CG 1 ATOM 5227 C CD1 . LEU A 1 651 ? 33.838 91.249 -33.550 1.00 23.27 ? 651 LEU A CD1 1 ATOM 5228 C CD2 . LEU A 1 651 ? 35.099 89.309 -32.638 1.00 19.52 ? 651 LEU A CD2 1 ATOM 5229 N N . LEU A 1 652 ? 32.454 88.266 -35.494 1.00 14.65 ? 652 LEU A N 1 ATOM 5230 C CA . LEU A 1 652 ? 31.082 88.358 -35.894 1.00 14.84 ? 652 LEU A CA 1 ATOM 5231 C C . LEU A 1 652 ? 30.278 89.055 -34.824 1.00 16.66 ? 652 LEU A C 1 ATOM 5232 O O . LEU A 1 652 ? 30.123 88.552 -33.687 1.00 16.02 ? 652 LEU A O 1 ATOM 5233 C CB . LEU A 1 652 ? 30.505 86.958 -36.159 1.00 14.72 ? 652 LEU A CB 1 ATOM 5234 C CG . LEU A 1 652 ? 31.223 86.183 -37.253 1.00 14.65 ? 652 LEU A CG 1 ATOM 5235 C CD1 . LEU A 1 652 ? 30.686 84.745 -37.366 1.00 16.30 ? 652 LEU A CD1 1 ATOM 5236 C CD2 . LEU A 1 652 ? 31.057 86.945 -38.625 1.00 16.45 ? 652 LEU A CD2 1 ATOM 5237 N N . ARG A 1 653 ? 29.772 90.240 -35.171 1.00 17.56 ? 653 ARG A N 1 ATOM 5238 C CA . ARG A 1 653 ? 28.953 91.043 -34.307 1.00 20.22 ? 653 ARG A CA 1 ATOM 5239 C C . ARG A 1 653 ? 28.478 92.252 -35.139 1.00 20.45 ? 653 ARG A C 1 ATOM 5240 O O . ARG A 1 653 ? 29.124 92.648 -36.109 1.00 20.93 ? 653 ARG A O 1 ATOM 5241 C CB . ARG A 1 653 ? 29.746 91.533 -33.117 1.00 22.06 ? 653 ARG A CB 1 ATOM 5242 C CG . ARG A 1 653 ? 30.860 92.423 -33.491 1.00 24.50 ? 653 ARG A CG 1 ATOM 5243 C CD . ARG A 1 653 ? 30.637 93.665 -32.700 1.00 28.84 ? 653 ARG A CD 1 ATOM 5244 N NE . ARG A 1 653 ? 31.310 93.660 -31.420 1.00 29.45 ? 653 ARG A NE 1 ATOM 5245 C CZ . ARG A 1 653 ? 31.004 94.463 -30.401 1.00 31.09 ? 653 ARG A CZ 1 ATOM 5246 N NH1 . ARG A 1 653 ? 30.010 95.337 -30.491 1.00 33.29 ? 653 ARG A NH1 1 ATOM 5247 N NH2 . ARG A 1 653 ? 31.749 94.460 -29.312 1.00 32.71 ? 653 ARG A NH2 1 ATOM 5248 N N . LYS A 1 654 ? 27.323 92.780 -34.775 1.00 22.78 ? 654 LYS A N 1 ATOM 5249 C CA . LYS A 1 654 ? 26.845 93.970 -35.469 1.00 24.98 ? 654 LYS A CA 1 ATOM 5250 C C . LYS A 1 654 ? 27.618 95.145 -34.833 1.00 25.55 ? 654 LYS A C 1 ATOM 5251 O O . LYS A 1 654 ? 28.087 95.033 -33.709 1.00 25.92 ? 654 LYS A O 1 ATOM 5252 C CB . LYS A 1 654 ? 25.335 94.087 -35.277 1.00 27.06 ? 654 LYS A CB 1 ATOM 5253 C CG . LYS A 1 654 ? 24.577 92.990 -36.035 1.00 30.56 ? 654 LYS A CG 1 ATOM 5254 C CD . LYS A 1 654 ? 23.101 93.322 -36.245 1.00 34.32 ? 654 LYS A CD 1 ATOM 5255 C CE . LYS A 1 654 ? 22.939 94.502 -37.208 1.00 36.02 ? 654 LYS A CE 1 ATOM 5256 N NZ . LYS A 1 654 ? 21.549 95.088 -37.193 1.00 38.13 ? 654 LYS A NZ 1 ATOM 5257 N N . ASN A 1 655 ? 27.789 96.255 -35.530 1.00 27.16 ? 655 ASN A N 1 ATOM 5258 C CA . ASN A 1 655 ? 28.482 97.381 -34.890 1.00 27.11 ? 655 ASN A CA 1 ATOM 5259 C C . ASN A 1 655 ? 29.889 97.022 -34.400 1.00 25.44 ? 655 ASN A C 1 ATOM 5260 O O . ASN A 1 655 ? 30.219 97.218 -33.227 1.00 25.72 ? 655 ASN A O 1 ATOM 5261 C CB . ASN A 1 655 ? 27.678 97.877 -33.680 1.00 30.21 ? 655 ASN A CB 1 ATOM 5262 C CG . ASN A 1 655 ? 28.103 99.277 -33.217 1.00 33.09 ? 655 ASN A CG 1 ATOM 5263 O OD1 . ASN A 1 655 ? 28.520 99.474 -32.053 1.00 34.71 ? 655 ASN A OD1 1 ATOM 5264 N ND2 . ASN A 1 655 ? 27.980 100.268 -34.121 1.00 34.88 ? 655 ASN A ND2 1 ATOM 5265 N N . PRO A 1 656 ? 30.740 96.497 -35.292 1.00 22.42 ? 656 PRO A N 1 ATOM 5266 C CA . PRO A 1 656 ? 32.101 96.134 -34.884 1.00 20.78 ? 656 PRO A CA 1 ATOM 5267 C C . PRO A 1 656 ? 32.977 97.375 -34.865 1.00 19.45 ? 656 PRO A C 1 ATOM 5268 O O . PRO A 1 656 ? 32.629 98.406 -35.469 1.00 18.69 ? 656 PRO A O 1 ATOM 5269 C CB . PRO A 1 656 ? 32.553 95.190 -35.987 1.00 20.35 ? 656 PRO A CB 1 ATOM 5270 C CG . PRO A 1 656 ? 31.849 95.738 -37.193 1.00 19.95 ? 656 PRO A CG 1 ATOM 5271 C CD . PRO A 1 656 ? 30.459 96.070 -36.675 1.00 21.78 ? 656 PRO A CD 1 ATOM 5272 N N . THR A 1 657 ? 34.088 97.278 -34.151 1.00 19.12 ? 657 THR A N 1 ATOM 5273 C CA . THR A 1 657 ? 35.079 98.333 -34.142 1.00 18.91 ? 657 THR A CA 1 ATOM 5274 C C . THR A 1 657 ? 36.358 97.595 -34.492 1.00 18.08 ? 657 THR A C 1 ATOM 5275 O O . THR A 1 657 ? 36.431 96.341 -34.385 1.00 18.16 ? 657 THR A O 1 ATOM 5276 C CB . THR A 1 657 ? 35.188 99.042 -32.804 1.00 19.46 ? 657 THR A CB 1 ATOM 5277 O OG1 . THR A 1 657 ? 35.303 98.072 -31.753 1.00 22.43 ? 657 THR A OG1 1 ATOM 5278 C CG2 . THR A 1 657 ? 33.944 99.916 -32.582 1.00 20.46 ? 657 THR A CG2 1 ATOM 5279 N N . SER A 1 658 ? 37.364 98.354 -34.889 1.00 17.03 ? 658 SER A N 1 ATOM 5280 C CA . SER A 1 658 ? 38.632 97.828 -35.376 1.00 17.31 ? 658 SER A CA 1 ATOM 5281 C C . SER A 1 658 ? 39.378 96.999 -34.314 1.00 17.65 ? 658 SER A C 1 ATOM 5282 O O . SER A 1 658 ? 39.168 97.184 -33.105 1.00 18.41 ? 658 SER A O 1 ATOM 5283 C CB . SER A 1 658 ? 39.498 98.991 -35.823 1.00 18.41 ? 658 SER A CB 1 ATOM 5284 O OG . SER A 1 658 ? 39.927 99.702 -34.671 1.00 19.40 ? 658 SER A OG 1 ATOM 5285 N N . LEU A 1 659 ? 40.227 96.085 -34.775 1.00 16.78 ? 659 LEU A N 1 ATOM 5286 C CA . LEU A 1 659 ? 41.000 95.208 -33.848 1.00 17.38 ? 659 LEU A CA 1 ATOM 5287 C C . LEU A 1 659 ? 42.412 95.131 -34.412 1.00 17.77 ? 659 LEU A C 1 ATOM 5288 O O . LEU A 1 659 ? 42.755 94.225 -35.175 1.00 17.27 ? 659 LEU A O 1 ATOM 5289 C CB . LEU A 1 659 ? 40.371 93.781 -33.794 1.00 18.33 ? 659 LEU A CB 1 ATOM 5290 C CG . LEU A 1 659 ? 39.010 93.677 -33.112 1.00 19.41 ? 659 LEU A CG 1 ATOM 5291 C CD1 . LEU A 1 659 ? 38.457 92.249 -33.299 1.00 20.41 ? 659 LEU A CD1 1 ATOM 5292 C CD2 . LEU A 1 659 ? 39.116 94.039 -31.644 1.00 19.95 ? 659 LEU A CD2 1 ATOM 5293 N N . PRO A 1 660 ? 43.236 96.141 -34.112 1.00 18.71 ? 660 PRO A N 1 ATOM 5294 C CA . PRO A 1 660 ? 44.599 96.125 -34.624 1.00 18.44 ? 660 PRO A CA 1 ATOM 5295 C C . PRO A 1 660 ? 45.391 95.024 -33.891 1.00 17.42 ? 660 PRO A C 1 ATOM 5296 O O . PRO A 1 660 ? 45.127 94.723 -32.733 1.00 17.56 ? 660 PRO A O 1 ATOM 5297 C CB . PRO A 1 660 ? 45.104 97.539 -34.312 1.00 19.69 ? 660 PRO A CB 1 ATOM 5298 C CG . PRO A 1 660 ? 44.396 97.900 -33.100 1.00 20.67 ? 660 PRO A CG 1 ATOM 5299 C CD . PRO A 1 660 ? 42.964 97.356 -33.331 1.00 19.13 ? 660 PRO A CD 1 ATOM 5300 N N . LEU A 1 661 ? 46.376 94.475 -34.583 1.00 18.18 ? 661 LEU A N 1 ATOM 5301 C CA . LEU A 1 661 ? 47.165 93.359 -34.007 1.00 17.91 ? 661 LEU A CA 1 ATOM 5302 C C . LEU A 1 661 ? 48.698 93.544 -34.133 1.00 19.04 ? 661 LEU A C 1 ATOM 5303 O O . LEU A 1 661 ? 49.444 92.566 -34.304 1.00 17.24 ? 661 LEU A O 1 ATOM 5304 C CB . LEU A 1 661 ? 46.749 92.076 -34.715 1.00 17.68 ? 661 LEU A CB 1 ATOM 5305 C CG . LEU A 1 661 ? 45.315 91.615 -34.497 1.00 16.27 ? 661 LEU A CG 1 ATOM 5306 C CD1 . LEU A 1 661 ? 45.059 90.311 -35.339 1.00 16.56 ? 661 LEU A CD1 1 ATOM 5307 C CD2 . LEU A 1 661 ? 45.132 91.351 -33.009 1.00 16.95 ? 661 LEU A CD2 1 ATOM 5308 N N . GLY A 1 662 ? 49.171 94.789 -34.087 1.00 20.41 ? 662 GLY A N 1 ATOM 5309 C CA . GLY A 1 662 ? 50.622 95.031 -34.193 1.00 20.46 ? 662 GLY A CA 1 ATOM 5310 C C . GLY A 1 662 ? 51.212 94.513 -35.494 1.00 20.93 ? 662 GLY A C 1 ATOM 5311 O O . GLY A 1 662 ? 50.694 94.762 -36.565 1.00 22.14 ? 662 GLY A O 1 ATOM 5312 N N . GLN A 1 663 ? 52.277 93.709 -35.411 1.00 20.68 ? 663 GLN A N 1 ATOM 5313 C CA . GLN A 1 663 ? 52.878 93.199 -36.622 1.00 20.95 ? 663 GLN A CA 1 ATOM 5314 C C . GLN A 1 663 ? 52.177 91.977 -37.228 1.00 19.14 ? 663 GLN A C 1 ATOM 5315 O O . GLN A 1 663 ? 52.578 91.519 -38.274 1.00 20.13 ? 663 GLN A O 1 ATOM 5316 C CB . GLN A 1 663 ? 54.333 92.785 -36.391 1.00 22.86 ? 663 GLN A CB 1 ATOM 5317 C CG . GLN A 1 663 ? 55.191 93.714 -35.521 1.00 26.10 ? 663 GLN A CG 1 ATOM 5318 C CD . GLN A 1 663 ? 56.480 92.995 -35.130 1.00 26.76 ? 663 GLN A CD 1 ATOM 5319 O OE1 . GLN A 1 663 ? 57.361 92.814 -35.996 1.00 27.35 ? 663 GLN A OE1 1 ATOM 5320 N NE2 . GLN A 1 663 ? 56.583 92.529 -33.852 1.00 27.51 ? 663 GLN A NE2 1 ATOM 5321 N N . TYR A 1 664 ? 51.123 91.464 -36.583 1.00 18.61 ? 664 TYR A N 1 ATOM 5322 C CA . TYR A 1 664 ? 50.464 90.275 -37.156 1.00 17.48 ? 664 TYR A CA 1 ATOM 5323 C C . TYR A 1 664 ? 50.158 90.565 -38.628 1.00 17.08 ? 664 TYR A C 1 ATOM 5324 O O . TYR A 1 664 ? 49.499 91.561 -38.929 1.00 18.18 ? 664 TYR A O 1 ATOM 5325 C CB . TYR A 1 664 ? 49.217 90.015 -36.340 1.00 15.27 ? 664 TYR A CB 1 ATOM 5326 C CG . TYR A 1 664 ? 48.625 88.669 -36.642 1.00 14.19 ? 664 TYR A CG 1 ATOM 5327 C CD1 . TYR A 1 664 ? 49.175 87.513 -36.068 1.00 12.54 ? 664 TYR A CD1 1 ATOM 5328 C CD2 . TYR A 1 664 ? 47.512 88.541 -37.474 1.00 12.52 ? 664 TYR A CD2 1 ATOM 5329 C CE1 . TYR A 1 664 ? 48.626 86.285 -36.301 1.00 13.82 ? 664 TYR A CE1 1 ATOM 5330 C CE2 . TYR A 1 664 ? 46.957 87.302 -37.739 1.00 13.57 ? 664 TYR A CE2 1 ATOM 5331 C CZ . TYR A 1 664 ? 47.527 86.181 -37.124 1.00 12.02 ? 664 TYR A CZ 1 ATOM 5332 O OH . TYR A 1 664 ? 46.922 84.992 -37.337 1.00 13.09 ? 664 TYR A OH 1 ATOM 5333 N N . PRO A 1 665 ? 50.544 89.684 -39.544 1.00 17.87 ? 665 PRO A N 1 ATOM 5334 C CA . PRO A 1 665 ? 50.307 89.985 -40.972 1.00 18.52 ? 665 PRO A CA 1 ATOM 5335 C C . PRO A 1 665 ? 48.991 89.938 -41.665 1.00 19.88 ? 665 PRO A C 1 ATOM 5336 O O . PRO A 1 665 ? 48.904 90.398 -42.807 1.00 22.32 ? 665 PRO A O 1 ATOM 5337 C CB . PRO A 1 665 ? 51.116 88.905 -41.690 1.00 18.75 ? 665 PRO A CB 1 ATOM 5338 C CG . PRO A 1 665 ? 51.117 87.750 -40.747 1.00 19.02 ? 665 PRO A CG 1 ATOM 5339 C CD . PRO A 1 665 ? 51.013 88.338 -39.368 1.00 18.17 ? 665 PRO A CD 1 ATOM 5340 N N . GLU A 1 666 ? 47.973 89.381 -41.024 1.00 19.34 ? 666 GLU A N 1 ATOM 5341 C CA . GLU A 1 666 ? 46.655 89.307 -41.651 1.00 19.20 ? 666 GLU A CA 1 ATOM 5342 C C . GLU A 1 666 ? 45.718 90.201 -40.872 1.00 18.16 ? 666 GLU A C 1 ATOM 5343 O O A GLU A 1 666 ? 45.654 90.136 -39.642 0.50 16.85 ? 666 GLU A O 1 ATOM 5344 O O B GLU A 1 666 ? 45.475 89.991 -39.668 0.50 17.19 ? 666 GLU A O 1 ATOM 5345 C CB . GLU A 1 666 ? 46.114 87.870 -41.628 1.00 21.13 ? 666 GLU A CB 1 ATOM 5346 C CG A GLU A 1 666 ? 44.655 87.798 -42.008 0.50 23.73 ? 666 GLU A CG 1 ATOM 5347 C CG B GLU A 1 666 ? 47.070 86.901 -42.347 0.50 23.58 ? 666 GLU A CG 1 ATOM 5348 C CD A GLU A 1 666 ? 44.373 86.876 -43.172 0.50 24.49 ? 666 GLU A CD 1 ATOM 5349 C CD B GLU A 1 666 ? 46.984 87.225 -43.821 0.50 24.88 ? 666 GLU A CD 1 ATOM 5350 O OE1 A GLU A 1 666 ? 45.301 86.619 -43.966 0.50 25.85 ? 666 GLU A OE1 1 ATOM 5351 O OE1 B GLU A 1 666 ? 45.924 86.964 -44.412 0.50 25.84 ? 666 GLU A OE1 1 ATOM 5352 O OE2 A GLU A 1 666 ? 43.218 86.430 -43.303 0.50 23.30 ? 666 GLU A OE2 1 ATOM 5353 O OE2 B GLU A 1 666 ? 47.962 87.759 -44.387 0.50 26.94 ? 666 GLU A OE2 1 ATOM 5354 N N . ASP A 1 667 ? 44.999 91.062 -41.586 1.00 17.19 ? 667 ASP A N 1 ATOM 5355 C CA . ASP A 1 667 ? 44.045 91.951 -40.939 1.00 16.93 ? 667 ASP A CA 1 ATOM 5356 C C . ASP A 1 667 ? 42.784 91.175 -40.485 1.00 14.63 ? 667 ASP A C 1 ATOM 5357 O O . ASP A 1 667 ? 42.300 90.320 -41.202 1.00 13.73 ? 667 ASP A O 1 ATOM 5358 C CB . ASP A 1 667 ? 43.543 93.039 -41.934 1.00 18.94 ? 667 ASP A CB 1 ATOM 5359 C CG . ASP A 1 667 ? 44.626 94.025 -42.338 1.00 21.79 ? 667 ASP A CG 1 ATOM 5360 O OD1 . ASP A 1 667 ? 45.632 94.184 -41.587 1.00 24.91 ? 667 ASP A OD1 1 ATOM 5361 O OD2 . ASP A 1 667 ? 44.467 94.685 -43.406 1.00 24.30 ? 667 ASP A OD2 1 ATOM 5362 N N . VAL A 1 668 ? 42.275 91.498 -39.310 1.00 13.91 ? 668 VAL A N 1 ATOM 5363 C CA . VAL A 1 668 ? 41.031 90.894 -38.813 1.00 14.15 ? 668 VAL A CA 1 ATOM 5364 C C . VAL A 1 668 ? 39.876 91.294 -39.765 1.00 14.26 ? 668 VAL A C 1 ATOM 5365 O O . VAL A 1 668 ? 39.817 92.458 -40.264 1.00 14.77 ? 668 VAL A O 1 ATOM 5366 C CB . VAL A 1 668 ? 40.668 91.393 -37.388 1.00 15.30 ? 668 VAL A CB 1 ATOM 5367 C CG1 . VAL A 1 668 ? 39.329 90.769 -36.932 1.00 14.80 ? 668 VAL A CG1 1 ATOM 5368 C CG2 . VAL A 1 668 ? 41.776 90.975 -36.395 1.00 15.47 ? 668 VAL A CG2 1 ATOM 5369 N N . LYS A 1 669 ? 38.977 90.348 -40.014 1.00 12.72 ? 669 LYS A N 1 ATOM 5370 C CA . LYS A 1 669 ? 37.782 90.505 -40.877 1.00 13.40 ? 669 LYS A CA 1 ATOM 5371 C C . LYS A 1 669 ? 36.557 90.614 -39.955 1.00 12.40 ? 669 LYS A C 1 ATOM 5372 O O . LYS A 1 669 ? 36.553 90.055 -38.831 1.00 12.84 ? 669 LYS A O 1 ATOM 5373 C CB . LYS A 1 669 ? 37.636 89.301 -41.789 1.00 16.68 ? 669 LYS A CB 1 ATOM 5374 C CG . LYS A 1 669 ? 38.597 89.264 -42.976 1.00 22.86 ? 669 LYS A CG 1 ATOM 5375 C CD . LYS A 1 669 ? 40.097 89.106 -42.656 1.00 27.01 ? 669 LYS A CD 1 ATOM 5376 C CE . LYS A 1 669 ? 40.994 89.794 -43.769 1.00 28.79 ? 669 LYS A CE 1 ATOM 5377 N NZ . LYS A 1 669 ? 40.469 89.542 -45.166 1.00 31.86 ? 669 LYS A NZ 1 ATOM 5378 N N . PHE A 1 670 ? 35.513 91.300 -40.396 1.00 12.90 ? 670 PHE A N 1 ATOM 5379 C CA . PHE A 1 670 ? 34.314 91.506 -39.603 1.00 13.40 ? 670 PHE A CA 1 ATOM 5380 C C . PHE A 1 670 ? 33.087 91.090 -40.374 1.00 14.11 ? 670 PHE A C 1 ATOM 5381 O O . PHE A 1 670 ? 33.094 91.047 -41.585 1.00 15.38 ? 670 PHE A O 1 ATOM 5382 C CB . PHE A 1 670 ? 34.175 92.969 -39.184 1.00 14.41 ? 670 PHE A CB 1 ATOM 5383 C CG . PHE A 1 670 ? 35.339 93.464 -38.406 1.00 15.16 ? 670 PHE A CG 1 ATOM 5384 C CD1 . PHE A 1 670 ? 36.478 93.916 -39.071 1.00 15.99 ? 670 PHE A CD1 1 ATOM 5385 C CD2 . PHE A 1 670 ? 35.330 93.399 -37.015 1.00 16.37 ? 670 PHE A CD2 1 ATOM 5386 C CE1 . PHE A 1 670 ? 37.613 94.300 -38.328 1.00 15.83 ? 670 PHE A CE1 1 ATOM 5387 C CE2 . PHE A 1 670 ? 36.453 93.775 -36.271 1.00 16.99 ? 670 PHE A CE2 1 ATOM 5388 C CZ . PHE A 1 670 ? 37.593 94.228 -36.944 1.00 16.07 ? 670 PHE A CZ 1 ATOM 5389 N N . GLY A 1 671 ? 32.020 90.741 -39.660 1.00 14.35 ? 671 GLY A N 1 ATOM 5390 C CA . GLY A 1 671 ? 30.773 90.377 -40.333 1.00 14.65 ? 671 GLY A CA 1 ATOM 5391 C C . GLY A 1 671 ? 29.628 90.314 -39.337 1.00 15.53 ? 671 GLY A C 1 ATOM 5392 O O . GLY A 1 671 ? 29.826 90.296 -38.115 1.00 14.80 ? 671 GLY A O 1 ATOM 5393 N N . ASP A 1 672 ? 28.398 90.301 -39.829 1.00 16.04 ? 672 ASP A N 1 ATOM 5394 C CA . ASP A 1 672 ? 27.273 90.164 -38.921 1.00 16.82 ? 672 ASP A CA 1 ATOM 5395 C C . ASP A 1 672 ? 27.218 88.688 -38.469 1.00 15.89 ? 672 ASP A C 1 ATOM 5396 O O . ASP A 1 672 ? 27.703 87.814 -39.183 1.00 15.26 ? 672 ASP A O 1 ATOM 5397 C CB . ASP A 1 672 ? 25.963 90.439 -39.665 1.00 19.79 ? 672 ASP A CB 1 ATOM 5398 C CG . ASP A 1 672 ? 25.667 91.911 -39.836 1.00 22.05 ? 672 ASP A CG 1 ATOM 5399 O OD1 . ASP A 1 672 ? 26.362 92.772 -39.266 1.00 23.00 ? 672 ASP A OD1 1 ATOM 5400 O OD2 . ASP A 1 672 ? 24.680 92.194 -40.552 1.00 25.81 ? 672 ASP A OD2 1 ATOM 5401 N N . PRO A 1 673 ? 26.645 88.425 -37.279 1.00 16.89 ? 673 PRO A N 1 ATOM 5402 C CA . PRO A 1 673 ? 26.539 87.026 -36.805 1.00 17.18 ? 673 PRO A CA 1 ATOM 5403 C C . PRO A 1 673 ? 25.943 86.158 -37.910 1.00 16.88 ? 673 PRO A C 1 ATOM 5404 O O . PRO A 1 673 ? 24.991 86.559 -38.625 1.00 17.86 ? 673 PRO A O 1 ATOM 5405 C CB . PRO A 1 673 ? 25.625 87.153 -35.596 1.00 18.08 ? 673 PRO A CB 1 ATOM 5406 C CG . PRO A 1 673 ? 25.956 88.491 -35.028 1.00 18.85 ? 673 PRO A CG 1 ATOM 5407 C CD . PRO A 1 673 ? 26.120 89.370 -36.275 1.00 18.12 ? 673 PRO A CD 1 ATOM 5408 N N . ARG A 1 674 ? 26.470 84.954 -38.052 1.00 16.15 ? 674 ARG A N 1 ATOM 5409 C CA . ARG A 1 674 ? 26.001 84.027 -39.078 1.00 16.24 ? 674 ARG A CA 1 ATOM 5410 C C . ARG A 1 674 ? 26.423 82.606 -38.740 1.00 17.10 ? 674 ARG A C 1 ATOM 5411 O O . ARG A 1 674 ? 27.356 82.411 -37.951 1.00 16.80 ? 674 ARG A O 1 ATOM 5412 C CB . ARG A 1 674 ? 26.588 84.395 -40.452 1.00 17.44 ? 674 ARG A CB 1 ATOM 5413 C CG . ARG A 1 674 ? 28.106 84.309 -40.597 1.00 19.56 ? 674 ARG A CG 1 ATOM 5414 C CD . ARG A 1 674 ? 28.418 84.342 -42.096 1.00 21.78 ? 674 ARG A CD 1 ATOM 5415 N NE . ARG A 1 674 ? 29.792 84.016 -42.448 1.00 24.42 ? 674 ARG A NE 1 ATOM 5416 C CZ . ARG A 1 674 ? 30.768 84.910 -42.592 1.00 24.60 ? 674 ARG A CZ 1 ATOM 5417 N NH1 . ARG A 1 674 ? 30.555 86.221 -42.402 1.00 26.11 ? 674 ARG A NH1 1 ATOM 5418 N NH2 . ARG A 1 674 ? 31.955 84.488 -42.983 1.00 26.13 ? 674 ARG A NH2 1 ATOM 5419 N N . GLU A 1 675 ? 25.738 81.608 -39.282 1.00 17.15 ? 675 GLU A N 1 ATOM 5420 C CA . GLU A 1 675 ? 26.193 80.261 -39.043 1.00 17.42 ? 675 GLU A CA 1 ATOM 5421 C C . GLU A 1 675 ? 27.516 80.033 -39.760 1.00 18.53 ? 675 GLU A C 1 ATOM 5422 O O . GLU A 1 675 ? 27.803 80.638 -40.820 1.00 19.43 ? 675 GLU A O 1 ATOM 5423 C CB . GLU A 1 675 ? 25.131 79.247 -39.519 1.00 19.61 ? 675 GLU A CB 1 ATOM 5424 C CG . GLU A 1 675 ? 23.856 79.470 -38.798 1.00 22.92 ? 675 GLU A CG 1 ATOM 5425 C CD . GLU A 1 675 ? 22.953 78.252 -38.774 1.00 26.26 ? 675 GLU A CD 1 ATOM 5426 O OE1 . GLU A 1 675 ? 23.034 77.464 -39.749 1.00 28.07 ? 675 GLU A OE1 1 ATOM 5427 O OE2 . GLU A 1 675 ? 22.163 78.090 -37.782 1.00 28.00 ? 675 GLU A OE2 1 ATOM 5428 N N . ILE A 1 676 ? 28.379 79.191 -39.202 1.00 18.01 ? 676 ILE A N 1 ATOM 5429 C CA . ILE A 1 676 ? 29.608 78.917 -39.896 1.00 19.36 ? 676 ILE A CA 1 ATOM 5430 C C . ILE A 1 676 ? 30.027 77.480 -39.721 1.00 17.18 ? 676 ILE A C 1 ATOM 5431 O O . ILE A 1 676 ? 29.577 76.809 -38.789 1.00 17.53 ? 676 ILE A O 1 ATOM 5432 C CB . ILE A 1 676 ? 30.743 79.792 -39.464 1.00 21.67 ? 676 ILE A CB 1 ATOM 5433 C CG1 . ILE A 1 676 ? 31.074 79.521 -38.031 1.00 21.58 ? 676 ILE A CG1 1 ATOM 5434 C CG2 . ILE A 1 676 ? 30.426 81.250 -39.649 1.00 24.25 ? 676 ILE A CG2 1 ATOM 5435 C CD1 . ILE A 1 676 ? 32.520 79.191 -37.908 1.00 24.78 ? 676 ILE A CD1 1 ATOM 5436 N N . SER A 1 677 ? 30.885 77.036 -40.627 1.00 16.97 ? 677 SER A N 1 ATOM 5437 C CA . SER A 1 677 ? 31.398 75.670 -40.667 1.00 17.08 ? 677 SER A CA 1 ATOM 5438 C C . SER A 1 677 ? 32.920 75.670 -40.746 1.00 17.20 ? 677 SER A C 1 ATOM 5439 O O . SER A 1 677 ? 33.516 76.493 -41.438 1.00 17.95 ? 677 SER A O 1 ATOM 5440 C CB A SER A 1 677 ? 30.826 74.970 -41.908 0.50 18.65 ? 677 SER A CB 1 ATOM 5441 C CB B SER A 1 677 ? 30.752 74.763 -41.669 0.50 17.51 ? 677 SER A CB 1 ATOM 5442 O OG A SER A 1 677 ? 31.350 73.674 -42.048 0.50 19.95 ? 677 SER A OG 1 ATOM 5443 O OG B SER A 1 677 ? 29.402 74.488 -41.366 0.50 17.21 ? 677 SER A OG 1 ATOM 5444 N N . LEU A 1 678 ? 33.570 74.742 -40.042 1.00 15.91 ? 678 LEU A N 1 ATOM 5445 C CA . LEU A 1 678 ? 35.008 74.665 -40.073 1.00 15.30 ? 678 LEU A CA 1 ATOM 5446 C C . LEU A 1 678 ? 35.474 73.228 -40.133 1.00 15.16 ? 678 LEU A C 1 ATOM 5447 O O . LEU A 1 678 ? 34.804 72.325 -39.579 1.00 14.83 ? 678 LEU A O 1 ATOM 5448 C CB . LEU A 1 678 ? 35.622 75.225 -38.783 1.00 17.30 ? 678 LEU A CB 1 ATOM 5449 C CG . LEU A 1 678 ? 35.696 76.715 -38.514 1.00 17.38 ? 678 LEU A CG 1 ATOM 5450 C CD1 . LEU A 1 678 ? 36.048 76.897 -37.029 1.00 18.93 ? 678 LEU A CD1 1 ATOM 5451 C CD2 . LEU A 1 678 ? 36.766 77.352 -39.351 1.00 19.98 ? 678 LEU A CD2 1 ATOM 5452 N N . ARG A 1 679 ? 36.613 73.026 -40.768 1.00 14.19 ? 679 ARG A N 1 ATOM 5453 C CA . ARG A 1 679 ? 37.215 71.700 -40.828 1.00 16.43 ? 679 ARG A CA 1 ATOM 5454 C C . ARG A 1 679 ? 38.727 71.870 -40.825 1.00 16.60 ? 679 ARG A C 1 ATOM 5455 O O . ARG A 1 679 ? 39.301 72.648 -41.633 1.00 18.73 ? 679 ARG A O 1 ATOM 5456 C CB . ARG A 1 679 ? 36.758 70.955 -42.096 1.00 19.13 ? 679 ARG A CB 1 ATOM 5457 C CG . ARG A 1 679 ? 37.330 69.538 -42.171 1.00 20.80 ? 679 ARG A CG 1 ATOM 5458 C CD . ARG A 1 679 ? 37.153 68.972 -43.572 1.00 24.44 ? 679 ARG A CD 1 ATOM 5459 N NE . ARG A 1 679 ? 37.449 67.556 -43.533 1.00 28.62 ? 679 ARG A NE 1 ATOM 5460 C CZ . ARG A 1 679 ? 37.587 66.799 -44.609 1.00 30.54 ? 679 ARG A CZ 1 ATOM 5461 N NH1 . ARG A 1 679 ? 37.460 67.338 -45.820 1.00 32.56 ? 679 ARG A NH1 1 ATOM 5462 N NH2 . ARG A 1 679 ? 37.822 65.502 -44.468 1.00 32.60 ? 679 ARG A NH2 1 ATOM 5463 N N . VAL A 1 680 ? 39.391 71.203 -39.887 1.00 15.56 ? 680 VAL A N 1 ATOM 5464 C CA . VAL A 1 680 ? 40.822 71.205 -39.835 1.00 15.47 ? 680 VAL A CA 1 ATOM 5465 C C . VAL A 1 680 ? 41.345 69.850 -40.315 1.00 18.21 ? 680 VAL A C 1 ATOM 5466 O O . VAL A 1 680 ? 40.854 68.782 -39.892 1.00 17.86 ? 680 VAL A O 1 ATOM 5467 C CB . VAL A 1 680 ? 41.325 71.457 -38.392 1.00 14.59 ? 680 VAL A CB 1 ATOM 5468 C CG1 . VAL A 1 680 ? 42.806 71.263 -38.335 1.00 15.08 ? 680 VAL A CG1 1 ATOM 5469 C CG2 . VAL A 1 680 ? 40.906 72.931 -37.959 1.00 13.74 ? 680 VAL A CG2 1 ATOM 5470 N N . GLY A 1 681 ? 42.334 69.924 -41.208 1.00 18.88 ? 681 GLY A N 1 ATOM 5471 C CA . GLY A 1 681 ? 42.919 68.722 -41.779 1.00 22.55 ? 681 GLY A CA 1 ATOM 5472 C C . GLY A 1 681 ? 41.842 67.878 -42.471 1.00 23.99 ? 681 GLY A C 1 ATOM 5473 O O . GLY A 1 681 ? 40.964 68.386 -43.191 1.00 24.81 ? 681 GLY A O 1 ATOM 5474 N N . ASN A 1 682 ? 41.905 66.572 -42.212 1.00 27.45 ? 682 ASN A N 1 ATOM 5475 C CA . ASN A 1 682 ? 40.953 65.616 -42.781 1.00 28.96 ? 682 ASN A CA 1 ATOM 5476 C C . ASN A 1 682 ? 39.962 65.209 -41.712 1.00 28.82 ? 682 ASN A C 1 ATOM 5477 O O . ASN A 1 682 ? 39.174 64.271 -41.901 1.00 30.18 ? 682 ASN A O 1 ATOM 5478 C CB . ASN A 1 682 ? 41.676 64.363 -43.249 1.00 31.95 ? 682 ASN A CB 1 ATOM 5479 C CG . ASN A 1 682 ? 42.556 64.628 -44.421 1.00 34.22 ? 682 ASN A CG 1 ATOM 5480 O OD1 . ASN A 1 682 ? 42.100 65.156 -45.440 1.00 36.87 ? 682 ASN A OD1 1 ATOM 5481 N ND2 . ASN A 1 682 ? 43.836 64.274 -44.295 1.00 35.94 ? 682 ASN A ND2 1 ATOM 5482 N N . GLY A 1 683 ? 39.993 65.930 -40.595 1.00 27.11 ? 683 GLY A N 1 ATOM 5483 C CA . GLY A 1 683 ? 39.144 65.612 -39.474 1.00 24.71 ? 683 GLY A CA 1 ATOM 5484 C C . GLY A 1 683 ? 37.695 65.935 -39.688 1.00 22.30 ? 683 GLY A C 1 ATOM 5485 O O . GLY A 1 683 ? 37.285 66.165 -40.829 1.00 23.11 ? 683 GLY A O 1 ATOM 5486 N N . PRO A 1 684 ? 36.896 66.009 -38.601 1.00 20.34 ? 684 PRO A N 1 ATOM 5487 C CA . PRO A 1 684 ? 35.473 66.313 -38.765 1.00 18.85 ? 684 PRO A CA 1 ATOM 5488 C C . PRO A 1 684 ? 35.173 67.746 -39.179 1.00 17.15 ? 684 PRO A C 1 ATOM 5489 O O . PRO A 1 684 ? 35.994 68.626 -39.009 1.00 16.76 ? 684 PRO A O 1 ATOM 5490 C CB . PRO A 1 684 ? 34.871 65.991 -37.391 1.00 18.31 ? 684 PRO A CB 1 ATOM 5491 C CG . PRO A 1 684 ? 36.033 66.266 -36.416 1.00 20.56 ? 684 PRO A CG 1 ATOM 5492 C CD . PRO A 1 684 ? 37.260 65.815 -37.181 1.00 20.72 ? 684 PRO A CD 1 ATOM 5493 N N . THR A 1 685 ? 33.990 67.956 -39.723 1.00 16.21 ? 685 THR A N 1 ATOM 5494 C CA . THR A 1 685 ? 33.543 69.293 -40.089 1.00 15.87 ? 685 THR A CA 1 ATOM 5495 C C . THR A 1 685 ? 32.497 69.627 -39.045 1.00 16.31 ? 685 THR A C 1 ATOM 5496 O O . THR A 1 685 ? 31.563 68.861 -38.820 1.00 15.32 ? 685 THR A O 1 ATOM 5497 C CB . THR A 1 685 ? 32.942 69.326 -41.508 1.00 17.82 ? 685 THR A CB 1 ATOM 5498 O OG1 . THR A 1 685 ? 33.966 69.000 -42.439 1.00 18.85 ? 685 THR A OG1 1 ATOM 5499 C CG2 . THR A 1 685 ? 32.382 70.696 -41.804 1.00 18.31 ? 685 THR A CG2 1 ATOM 5500 N N . LEU A 1 686 ? 32.651 70.786 -38.387 1.00 14.38 ? 686 LEU A N 1 ATOM 5501 C CA . LEU A 1 686 ? 31.760 71.217 -37.339 1.00 14.43 ? 686 LEU A CA 1 ATOM 5502 C C . LEU A 1 686 ? 30.989 72.436 -37.808 1.00 13.30 ? 686 LEU A C 1 ATOM 5503 O O . LEU A 1 686 ? 31.588 73.377 -38.354 1.00 13.65 ? 686 LEU A O 1 ATOM 5504 C CB . LEU A 1 686 ? 32.552 71.614 -36.056 1.00 13.36 ? 686 LEU A CB 1 ATOM 5505 C CG . LEU A 1 686 ? 33.499 70.614 -35.374 1.00 18.44 ? 686 LEU A CG 1 ATOM 5506 C CD1 . LEU A 1 686 ? 33.562 70.980 -33.917 1.00 17.72 ? 686 LEU A CD1 1 ATOM 5507 C CD2 . LEU A 1 686 ? 33.190 69.203 -35.590 1.00 17.32 ? 686 LEU A CD2 1 ATOM 5508 N N . ALA A 1 687 ? 29.705 72.431 -37.543 1.00 12.63 ? 687 ALA A N 1 ATOM 5509 C CA . ALA A 1 687 ? 28.836 73.565 -37.839 1.00 12.72 ? 687 ALA A CA 1 ATOM 5510 C C . ALA A 1 687 ? 28.420 74.243 -36.558 1.00 13.70 ? 687 ALA A C 1 ATOM 5511 O O . ALA A 1 687 ? 28.073 73.597 -35.572 1.00 13.97 ? 687 ALA A O 1 ATOM 5512 C CB . ALA A 1 687 ? 27.567 73.103 -38.609 1.00 13.51 ? 687 ALA A CB 1 ATOM 5513 N N . PHE A 1 688 ? 28.354 75.560 -36.603 1.00 12.05 ? 688 PHE A N 1 ATOM 5514 C CA . PHE A 1 688 ? 28.030 76.374 -35.465 1.00 12.14 ? 688 PHE A CA 1 ATOM 5515 C C . PHE A 1 688 ? 26.862 77.299 -35.714 1.00 12.08 ? 688 PHE A C 1 ATOM 5516 O O . PHE A 1 688 ? 26.686 77.795 -36.857 1.00 14.70 ? 688 PHE A O 1 ATOM 5517 C CB . PHE A 1 688 ? 29.238 77.258 -35.052 1.00 11.94 ? 688 PHE A CB 1 ATOM 5518 C CG . PHE A 1 688 ? 30.439 76.457 -34.673 1.00 11.26 ? 688 PHE A CG 1 ATOM 5519 C CD1 . PHE A 1 688 ? 31.290 75.988 -35.641 1.00 11.28 ? 688 PHE A CD1 1 ATOM 5520 C CD2 . PHE A 1 688 ? 30.698 76.174 -33.343 1.00 10.43 ? 688 PHE A CD2 1 ATOM 5521 C CE1 . PHE A 1 688 ? 32.434 75.233 -35.364 1.00 11.42 ? 688 PHE A CE1 1 ATOM 5522 C CE2 . PHE A 1 688 ? 31.825 75.428 -33.009 1.00 11.49 ? 688 PHE A CE2 1 ATOM 5523 C CZ . PHE A 1 688 ? 32.710 74.946 -34.012 1.00 10.80 ? 688 PHE A CZ 1 ATOM 5524 N N . SER A 1 689 ? 26.083 77.546 -34.703 1.00 12.81 ? 689 SER A N 1 ATOM 5525 C CA . SER A 1 689 ? 24.963 78.515 -34.768 1.00 14.24 ? 689 SER A CA 1 ATOM 5526 C C . SER A 1 689 ? 25.513 79.940 -34.833 1.00 14.58 ? 689 SER A C 1 ATOM 5527 O O . SER A 1 689 ? 26.722 80.178 -34.613 1.00 13.53 ? 689 SER A O 1 ATOM 5528 C CB . SER A 1 689 ? 24.118 78.414 -33.512 1.00 15.13 ? 689 SER A CB 1 ATOM 5529 O OG . SER A 1 689 ? 24.756 78.987 -32.390 1.00 14.81 ? 689 SER A OG 1 ATOM 5530 N N . GLU A 1 690 ? 24.631 80.896 -35.116 1.00 14.94 ? 690 GLU A N 1 ATOM 5531 C CA . GLU A 1 690 ? 25.037 82.292 -35.134 1.00 15.61 ? 690 GLU A CA 1 ATOM 5532 C C . GLU A 1 690 ? 25.426 82.778 -33.737 1.00 15.85 ? 690 GLU A C 1 ATOM 5533 O O . GLU A 1 690 ? 25.994 83.861 -33.596 1.00 14.71 ? 690 GLU A O 1 ATOM 5534 C CB . GLU A 1 690 ? 23.910 83.149 -35.757 1.00 18.33 ? 690 GLU A CB 1 ATOM 5535 C CG . GLU A 1 690 ? 22.811 83.553 -34.879 1.00 21.98 ? 690 GLU A CG 1 ATOM 5536 C CD . GLU A 1 690 ? 21.943 84.632 -35.578 1.00 24.44 ? 690 GLU A CD 1 ATOM 5537 O OE1 . GLU A 1 690 ? 21.435 84.326 -36.680 1.00 27.19 ? 690 GLU A OE1 1 ATOM 5538 O OE2 . GLU A 1 690 ? 21.797 85.765 -35.042 1.00 27.45 ? 690 GLU A OE2 1 ATOM 5539 N N . GLN A 1 691 ? 25.097 82.011 -32.684 1.00 15.19 ? 691 GLN A N 1 ATOM 5540 C CA . GLN A 1 691 ? 25.551 82.382 -31.342 1.00 15.88 ? 691 GLN A CA 1 ATOM 5541 C C . GLN A 1 691 ? 26.871 81.696 -30.970 1.00 13.88 ? 691 GLN A C 1 ATOM 5542 O O . GLN A 1 691 ? 27.266 81.765 -29.830 1.00 15.26 ? 691 GLN A O 1 ATOM 5543 C CB . GLN A 1 691 ? 24.550 82.067 -30.245 1.00 17.03 ? 691 GLN A CB 1 ATOM 5544 C CG . GLN A 1 691 ? 23.270 82.817 -30.370 1.00 21.15 ? 691 GLN A CG 1 ATOM 5545 C CD . GLN A 1 691 ? 22.249 81.807 -30.590 1.00 26.02 ? 691 GLN A CD 1 ATOM 5546 O OE1 . GLN A 1 691 ? 21.727 81.205 -29.613 1.00 28.11 ? 691 GLN A OE1 1 ATOM 5547 N NE2 . GLN A 1 691 ? 21.995 81.505 -31.856 1.00 25.87 ? 691 GLN A NE2 1 ATOM 5548 N N . GLY A 1 692 ? 27.515 81.058 -31.924 1.00 12.98 ? 692 GLY A N 1 ATOM 5549 C CA . GLY A 1 692 ? 28.847 80.463 -31.698 1.00 12.98 ? 692 GLY A CA 1 ATOM 5550 C C . GLY A 1 692 ? 28.868 79.114 -31.018 1.00 12.91 ? 692 GLY A C 1 ATOM 5551 O O . GLY A 1 692 ? 29.918 78.693 -30.566 1.00 13.41 ? 692 GLY A O 1 ATOM 5552 N N . LEU A 1 693 ? 27.736 78.421 -30.993 1.00 12.32 ? 693 LEU A N 1 ATOM 5553 C CA . LEU A 1 693 ? 27.618 77.106 -30.324 1.00 11.96 ? 693 LEU A CA 1 ATOM 5554 C C . LEU A 1 693 ? 27.463 76.009 -31.348 1.00 12.52 ? 693 LEU A C 1 ATOM 5555 O O . LEU A 1 693 ? 26.759 76.148 -32.377 1.00 12.65 ? 693 LEU A O 1 ATOM 5556 C CB . LEU A 1 693 ? 26.423 77.118 -29.379 1.00 14.91 ? 693 LEU A CB 1 ATOM 5557 C CG . LEU A 1 693 ? 26.605 78.083 -28.197 1.00 16.50 ? 693 LEU A CG 1 ATOM 5558 C CD1 . LEU A 1 693 ? 25.292 78.807 -27.958 1.00 20.43 ? 693 LEU A CD1 1 ATOM 5559 C CD2 . LEU A 1 693 ? 27.006 77.353 -26.925 1.00 18.22 ? 693 LEU A CD2 1 ATOM 5560 N N . LEU A 1 694 ? 28.108 74.877 -31.095 1.00 11.67 ? 694 LEU A N 1 ATOM 5561 C CA . LEU A 1 694 ? 28.043 73.732 -31.971 1.00 11.39 ? 694 LEU A CA 1 ATOM 5562 C C . LEU A 1 694 ? 26.599 73.316 -32.233 1.00 10.69 ? 694 LEU A C 1 ATOM 5563 O O . LEU A 1 694 ? 25.756 73.346 -31.331 1.00 11.89 ? 694 LEU A O 1 ATOM 5564 C CB . LEU A 1 694 ? 28.784 72.565 -31.277 1.00 11.71 ? 694 LEU A CB 1 ATOM 5565 C CG . LEU A 1 694 ? 28.923 71.332 -32.165 1.00 12.20 ? 694 LEU A CG 1 ATOM 5566 C CD1 . LEU A 1 694 ? 29.847 71.575 -33.317 1.00 13.11 ? 694 LEU A CD1 1 ATOM 5567 C CD2 . LEU A 1 694 ? 29.498 70.173 -31.297 1.00 12.61 ? 694 LEU A CD2 1 ATOM 5568 N N . LYS A 1 695 ? 26.348 72.996 -33.492 1.00 12.23 ? 695 LYS A N 1 ATOM 5569 C CA . LYS A 1 695 ? 25.051 72.531 -33.945 1.00 14.46 ? 695 LYS A CA 1 ATOM 5570 C C . LYS A 1 695 ? 25.159 71.153 -34.551 1.00 12.76 ? 695 LYS A C 1 ATOM 5571 O O . LYS A 1 695 ? 24.170 70.407 -34.427 1.00 14.36 ? 695 LYS A O 1 ATOM 5572 C CB . LYS A 1 695 ? 24.521 73.496 -35.019 1.00 19.41 ? 695 LYS A CB 1 ATOM 5573 C CG . LYS A 1 695 ? 23.081 73.508 -35.255 1.00 25.07 ? 695 LYS A CG 1 ATOM 5574 C CD . LYS A 1 695 ? 22.854 74.711 -36.216 1.00 28.66 ? 695 LYS A CD 1 ATOM 5575 C CE . LYS A 1 695 ? 21.468 74.744 -36.766 1.00 30.59 ? 695 LYS A CE 1 ATOM 5576 N NZ . LYS A 1 695 ? 21.510 75.235 -38.174 1.00 32.04 ? 695 LYS A NZ 1 ATOM 5577 N N . SER A 1 696 ? 26.248 70.793 -35.200 1.00 12.86 ? 696 SER A N 1 ATOM 5578 C CA . SER A 1 696 ? 26.372 69.486 -35.843 1.00 13.53 ? 696 SER A CA 1 ATOM 5579 C C . SER A 1 696 ? 27.781 69.101 -36.094 1.00 13.91 ? 696 SER A C 1 ATOM 5580 O O . SER A 1 696 ? 28.698 69.977 -36.150 1.00 13.04 ? 696 SER A O 1 ATOM 5581 C CB . SER A 1 696 ? 25.576 69.468 -37.182 1.00 16.77 ? 696 SER A CB 1 ATOM 5582 O OG . SER A 1 696 ? 26.265 70.206 -38.202 1.00 18.13 ? 696 SER A OG 1 ATOM 5583 N N . ILE A 1 697 ? 28.018 67.794 -36.249 1.00 14.74 ? 697 ILE A N 1 ATOM 5584 C CA . ILE A 1 697 ? 29.323 67.260 -36.547 1.00 14.61 ? 697 ILE A CA 1 ATOM 5585 C C . ILE A 1 697 ? 29.173 66.300 -37.714 1.00 16.59 ? 697 ILE A C 1 ATOM 5586 O O . ILE A 1 697 ? 28.257 65.459 -37.676 1.00 16.91 ? 697 ILE A O 1 ATOM 5587 C CB . ILE A 1 697 ? 29.967 66.445 -35.337 1.00 14.87 ? 697 ILE A CB 1 ATOM 5588 C CG1 . ILE A 1 697 ? 30.155 67.344 -34.131 1.00 14.81 ? 697 ILE A CG1 1 ATOM 5589 C CG2 . ILE A 1 697 ? 31.284 65.870 -35.716 1.00 15.26 ? 697 ILE A CG2 1 ATOM 5590 C CD1 . ILE A 1 697 ? 30.611 66.512 -32.892 1.00 14.63 ? 697 ILE A CD1 1 ATOM 5591 N N . GLN A 1 698 ? 30.010 66.465 -38.733 1.00 15.84 ? 698 GLN A N 1 ATOM 5592 C CA . GLN A 1 698 ? 30.005 65.591 -39.913 1.00 17.47 ? 698 GLN A CA 1 ATOM 5593 C C . GLN A 1 698 ? 31.357 64.907 -39.861 1.00 17.57 ? 698 GLN A C 1 ATOM 5594 O O . GLN A 1 698 ? 32.414 65.516 -40.015 1.00 17.23 ? 698 GLN A O 1 ATOM 5595 C CB . GLN A 1 698 ? 29.868 66.414 -41.204 1.00 18.08 ? 698 GLN A CB 1 ATOM 5596 C CG . GLN A 1 698 ? 29.804 65.477 -42.417 1.00 20.24 ? 698 GLN A CG 1 ATOM 5597 C CD . GLN A 1 698 ? 29.921 66.247 -43.701 1.00 22.17 ? 698 GLN A CD 1 ATOM 5598 O OE1 . GLN A 1 698 ? 29.074 66.119 -44.585 1.00 25.08 ? 698 GLN A OE1 1 ATOM 5599 N NE2 . GLN A 1 698 ? 30.958 67.055 -43.812 1.00 22.50 ? 698 GLN A NE2 1 ATOM 5600 N N . LEU A 1 699 ? 31.376 63.594 -39.632 1.00 19.99 ? 699 LEU A N 1 ATOM 5601 C CA . LEU A 1 699 ? 32.639 62.912 -39.482 1.00 21.80 ? 699 LEU A CA 1 ATOM 5602 C C . LEU A 1 699 ? 33.558 62.814 -40.676 1.00 25.03 ? 699 LEU A C 1 ATOM 5603 O O . LEU A 1 699 ? 34.773 62.931 -40.530 1.00 24.73 ? 699 LEU A O 1 ATOM 5604 C CB . LEU A 1 699 ? 32.425 61.496 -38.905 1.00 22.43 ? 699 LEU A CB 1 ATOM 5605 C CG . LEU A 1 699 ? 31.771 61.439 -37.512 1.00 21.47 ? 699 LEU A CG 1 ATOM 5606 C CD1 . LEU A 1 699 ? 31.582 59.950 -37.096 1.00 22.37 ? 699 LEU A CD1 1 ATOM 5607 C CD2 . LEU A 1 699 ? 32.627 62.163 -36.526 1.00 22.09 ? 699 LEU A CD2 1 ATOM 5608 N N . THR A 1 700 ? 32.981 62.613 -41.857 1.00 28.18 ? 700 THR A N 1 ATOM 5609 C CA . THR A 1 700 ? 33.772 62.456 -43.076 1.00 31.97 ? 700 THR A CA 1 ATOM 5610 C C . THR A 1 700 ? 33.070 63.188 -44.208 1.00 33.83 ? 700 THR A C 1 ATOM 5611 O O . THR A 1 700 ? 31.912 63.556 -44.070 1.00 33.75 ? 700 THR A O 1 ATOM 5612 C CB . THR A 1 700 ? 33.917 60.952 -43.465 1.00 31.81 ? 700 THR A CB 1 ATOM 5613 O OG1 . THR A 1 700 ? 32.616 60.388 -43.723 1.00 32.68 ? 700 THR A OG1 1 ATOM 5614 C CG2 . THR A 1 700 ? 34.578 60.164 -42.328 1.00 32.48 ? 700 THR A CG2 1 ATOM 5615 N N . GLN A 1 701 ? 33.785 63.398 -45.317 1.00 37.08 ? 701 GLN A N 1 ATOM 5616 C CA . GLN A 1 701 ? 33.249 64.098 -46.494 1.00 40.17 ? 701 GLN A CA 1 ATOM 5617 C C . GLN A 1 701 ? 31.836 63.700 -46.906 1.00 40.70 ? 701 GLN A C 1 ATOM 5618 O O . GLN A 1 701 ? 30.998 64.557 -47.210 1.00 41.39 ? 701 GLN A O 1 ATOM 5619 C CB . GLN A 1 701 ? 34.175 63.901 -47.706 1.00 42.19 ? 701 GLN A CB 1 ATOM 5620 C CG . GLN A 1 701 ? 35.411 64.808 -47.732 1.00 45.19 ? 701 GLN A CG 1 ATOM 5621 C CD . GLN A 1 701 ? 35.056 66.291 -47.863 1.00 46.99 ? 701 GLN A CD 1 ATOM 5622 O OE1 . GLN A 1 701 ? 35.943 67.149 -48.022 1.00 47.72 ? 701 GLN A OE1 1 ATOM 5623 N NE2 . GLN A 1 701 ? 33.756 66.604 -47.787 1.00 48.16 ? 701 GLN A NE2 1 ATOM 5624 N N . ASP A 1 702 ? 31.574 62.403 -46.901 1.00 41.22 ? 702 ASP A N 1 ATOM 5625 C CA . ASP A 1 702 ? 30.273 61.872 -47.287 1.00 41.65 ? 702 ASP A CA 1 ATOM 5626 C C . ASP A 1 702 ? 29.156 61.859 -46.229 1.00 40.74 ? 702 ASP A C 1 ATOM 5627 O O . ASP A 1 702 ? 28.000 62.230 -46.513 1.00 41.00 ? 702 ASP A O 1 ATOM 5628 C CB . ASP A 1 702 ? 30.468 60.443 -47.810 1.00 43.56 ? 702 ASP A CB 1 ATOM 5629 C CG . ASP A 1 702 ? 31.289 59.566 -46.847 1.00 45.20 ? 702 ASP A CG 1 ATOM 5630 O OD1 . ASP A 1 702 ? 32.395 60.001 -46.434 1.00 45.63 ? 702 ASP A OD1 1 ATOM 5631 O OD2 . ASP A 1 702 ? 30.832 58.440 -46.521 1.00 45.88 ? 702 ASP A OD2 1 ATOM 5632 N N . SER A 1 703 ? 29.521 61.440 -45.017 1.00 38.80 ? 703 SER A N 1 ATOM 5633 C CA . SER A 1 703 ? 28.593 61.275 -43.907 1.00 36.49 ? 703 SER A CA 1 ATOM 5634 C C . SER A 1 703 ? 27.610 62.390 -43.574 1.00 34.61 ? 703 SER A C 1 ATOM 5635 O O . SER A 1 703 ? 27.758 63.527 -44.008 1.00 34.71 ? 703 SER A O 1 ATOM 5636 C CB . SER A 1 703 ? 29.385 60.873 -42.659 1.00 36.98 ? 703 SER A CB 1 ATOM 5637 O OG . SER A 1 703 ? 30.217 61.926 -42.206 1.00 35.95 ? 703 SER A OG 1 ATOM 5638 N N . PRO A 1 704 ? 26.576 62.070 -42.782 1.00 32.73 ? 704 PRO A N 1 ATOM 5639 C CA . PRO A 1 704 ? 25.610 63.104 -42.435 1.00 30.91 ? 704 PRO A CA 1 ATOM 5640 C C . PRO A 1 704 ? 26.097 64.094 -41.387 1.00 28.88 ? 704 PRO A C 1 ATOM 5641 O O . PRO A 1 704 ? 27.060 63.842 -40.642 1.00 27.49 ? 704 PRO A O 1 ATOM 5642 C CB . PRO A 1 704 ? 24.397 62.312 -41.956 1.00 31.89 ? 704 PRO A CB 1 ATOM 5643 C CG . PRO A 1 704 ? 24.984 61.070 -41.437 1.00 32.64 ? 704 PRO A CG 1 ATOM 5644 C CD . PRO A 1 704 ? 26.101 60.737 -42.374 1.00 32.60 ? 704 PRO A CD 1 ATOM 5645 N N . HIS A 1 705 ? 25.430 65.240 -41.370 1.00 27.05 ? 705 HIS A N 1 ATOM 5646 C CA . HIS A 1 705 ? 25.736 66.281 -40.386 1.00 24.86 ? 705 HIS A CA 1 ATOM 5647 C C . HIS A 1 705 ? 24.863 65.868 -39.192 1.00 22.87 ? 705 HIS A C 1 ATOM 5648 O O . HIS A 1 705 ? 23.679 66.159 -39.121 1.00 23.28 ? 705 HIS A O 1 ATOM 5649 C CB . HIS A 1 705 ? 25.354 67.674 -40.963 1.00 26.94 ? 705 HIS A CB 1 ATOM 5650 C CG . HIS A 1 705 ? 26.244 68.127 -42.095 1.00 28.71 ? 705 HIS A CG 1 ATOM 5651 N ND1 . HIS A 1 705 ? 27.478 68.716 -41.889 1.00 28.86 ? 705 HIS A ND1 1 ATOM 5652 C CD2 . HIS A 1 705 ? 26.136 67.960 -43.438 1.00 29.27 ? 705 HIS A CD2 1 ATOM 5653 C CE1 . HIS A 1 705 ? 28.097 68.872 -43.047 1.00 30.11 ? 705 HIS A CE1 1 ATOM 5654 N NE2 . HIS A 1 705 ? 27.302 68.420 -44.007 1.00 30.21 ? 705 HIS A NE2 1 ATOM 5655 N N . VAL A 1 706 ? 25.500 65.204 -38.220 1.00 19.57 ? 706 VAL A N 1 ATOM 5656 C CA . VAL A 1 706 ? 24.817 64.700 -37.036 1.00 17.19 ? 706 VAL A CA 1 ATOM 5657 C C . VAL A 1 706 ? 24.483 65.804 -36.043 1.00 15.56 ? 706 VAL A C 1 ATOM 5658 O O . VAL A 1 706 ? 25.396 66.508 -35.590 1.00 14.92 ? 706 VAL A O 1 ATOM 5659 C CB . VAL A 1 706 ? 25.750 63.632 -36.345 1.00 17.27 ? 706 VAL A CB 1 ATOM 5660 C CG1 . VAL A 1 706 ? 25.059 63.034 -35.152 1.00 16.98 ? 706 VAL A CG1 1 ATOM 5661 C CG2 . VAL A 1 706 ? 26.189 62.581 -37.339 1.00 18.32 ? 706 VAL A CG2 1 ATOM 5662 N N . PRO A 1 707 ? 23.222 65.996 -35.661 1.00 15.27 ? 707 PRO A N 1 ATOM 5663 C CA . PRO A 1 707 ? 22.892 67.055 -34.712 1.00 15.86 ? 707 PRO A CA 1 ATOM 5664 C C . PRO A 1 707 ? 23.609 66.813 -33.372 1.00 15.56 ? 707 PRO A C 1 ATOM 5665 O O . PRO A 1 707 ? 23.455 65.728 -32.767 1.00 15.93 ? 707 PRO A O 1 ATOM 5666 C CB . PRO A 1 707 ? 21.366 66.947 -34.564 1.00 16.55 ? 707 PRO A CB 1 ATOM 5667 C CG . PRO A 1 707 ? 20.924 66.306 -35.843 1.00 17.92 ? 707 PRO A CG 1 ATOM 5668 C CD . PRO A 1 707 ? 21.994 65.301 -36.124 1.00 15.15 ? 707 PRO A CD 1 ATOM 5669 N N . VAL A 1 708 ? 24.414 67.795 -32.922 1.00 15.10 ? 708 VAL A N 1 ATOM 5670 C CA . VAL A 1 708 ? 25.107 67.749 -31.609 1.00 13.12 ? 708 VAL A CA 1 ATOM 5671 C C . VAL A 1 708 ? 25.042 69.225 -31.241 1.00 13.13 ? 708 VAL A C 1 ATOM 5672 O O . VAL A 1 708 ? 25.801 70.045 -31.790 1.00 14.30 ? 708 VAL A O 1 ATOM 5673 C CB . VAL A 1 708 ? 26.545 67.242 -31.728 1.00 13.75 ? 708 VAL A CB 1 ATOM 5674 C CG1 . VAL A 1 708 ? 27.191 67.209 -30.311 1.00 12.72 ? 708 VAL A CG1 1 ATOM 5675 C CG2 . VAL A 1 708 ? 26.565 65.817 -32.323 1.00 14.64 ? 708 VAL A CG2 1 ATOM 5676 N N . HIS A 1 709 ? 24.135 69.573 -30.358 1.00 12.68 ? 709 HIS A N 1 ATOM 5677 C CA . HIS A 1 709 ? 23.939 70.974 -30.004 1.00 13.54 ? 709 HIS A CA 1 ATOM 5678 C C . HIS A 1 709 ? 24.378 71.305 -28.577 1.00 13.12 ? 709 HIS A C 1 ATOM 5679 O O A HIS A 1 709 ? 23.948 70.631 -27.645 0.50 13.32 ? 709 HIS A O 1 ATOM 5680 O O B HIS A 1 709 ? 23.792 70.763 -27.606 0.50 13.12 ? 709 HIS A O 1 ATOM 5681 C CB A HIS A 1 709 ? 22.437 71.327 -30.122 0.50 15.86 ? 709 HIS A CB 1 ATOM 5682 C CB B HIS A 1 709 ? 22.552 71.403 -30.288 0.50 15.26 ? 709 HIS A CB 1 ATOM 5683 C CG A HIS A 1 709 ? 21.916 71.465 -31.526 0.50 18.67 ? 709 HIS A CG 1 ATOM 5684 C CG B HIS A 1 709 ? 22.258 72.840 -29.979 0.50 17.43 ? 709 HIS A CG 1 ATOM 5685 N ND1 A HIS A 1 709 ? 21.961 70.449 -32.458 0.50 20.73 ? 709 HIS A ND1 1 ATOM 5686 N ND1 B HIS A 1 709 ? 23.070 73.873 -30.399 0.50 18.40 ? 709 HIS A ND1 1 ATOM 5687 C CD2 A HIS A 1 709 ? 21.256 72.487 -32.122 0.50 20.49 ? 709 HIS A CD2 1 ATOM 5688 C CD2 B HIS A 1 709 ? 21.213 73.417 -29.339 0.50 18.30 ? 709 HIS A CD2 1 ATOM 5689 C CE1 A HIS A 1 709 ? 21.348 70.835 -33.562 0.50 18.48 ? 709 HIS A CE1 1 ATOM 5690 C CE1 B HIS A 1 709 ? 22.536 75.026 -30.030 0.50 18.86 ? 709 HIS A CE1 1 ATOM 5691 N NE2 A HIS A 1 709 ? 20.909 72.068 -33.384 0.50 21.11 ? 709 HIS A NE2 1 ATOM 5692 N NE2 B HIS A 1 709 ? 21.408 74.776 -29.389 0.50 19.21 ? 709 HIS A NE2 1 ATOM 5693 N N . PHE A 1 710 ? 25.262 72.300 -28.393 1.00 12.08 ? 710 PHE A N 1 ATOM 5694 C CA . PHE A 1 710 ? 25.629 72.739 -27.081 1.00 11.36 ? 710 PHE A CA 1 ATOM 5695 C C . PHE A 1 710 ? 24.634 73.834 -26.629 1.00 11.29 ? 710 PHE A C 1 ATOM 5696 O O . PHE A 1 710 ? 24.186 74.701 -27.445 1.00 12.06 ? 710 PHE A O 1 ATOM 5697 C CB . PHE A 1 710 ? 27.059 73.333 -27.053 1.00 12.02 ? 710 PHE A CB 1 ATOM 5698 C CG . PHE A 1 710 ? 28.153 72.361 -26.644 1.00 13.29 ? 710 PHE A CG 1 ATOM 5699 C CD1 . PHE A 1 710 ? 28.078 71.687 -25.442 1.00 15.17 ? 710 PHE A CD1 1 ATOM 5700 C CD2 . PHE A 1 710 ? 29.270 72.163 -27.442 1.00 14.74 ? 710 PHE A CD2 1 ATOM 5701 C CE1 . PHE A 1 710 ? 29.105 70.807 -25.025 1.00 15.31 ? 710 PHE A CE1 1 ATOM 5702 C CE2 . PHE A 1 710 ? 30.296 71.282 -27.008 1.00 13.75 ? 710 PHE A CE2 1 ATOM 5703 C CZ . PHE A 1 710 ? 30.193 70.627 -25.823 1.00 14.90 ? 710 PHE A CZ 1 ATOM 5704 N N . LYS A 1 711 ? 24.273 73.826 -25.359 1.00 11.09 ? 711 LYS A N 1 ATOM 5705 C CA . LYS A 1 711 ? 23.368 74.798 -24.785 1.00 13.03 ? 711 LYS A CA 1 ATOM 5706 C C . LYS A 1 711 ? 23.761 75.020 -23.349 1.00 12.95 ? 711 LYS A C 1 ATOM 5707 O O . LYS A 1 711 ? 24.185 74.056 -22.686 1.00 14.14 ? 711 LYS A O 1 ATOM 5708 C CB . LYS A 1 711 ? 21.912 74.270 -24.856 1.00 15.55 ? 711 LYS A CB 1 ATOM 5709 C CG . LYS A 1 711 ? 20.876 75.234 -24.366 1.00 18.65 ? 711 LYS A CG 1 ATOM 5710 C CD . LYS A 1 711 ? 19.434 74.657 -24.523 1.00 21.04 ? 711 LYS A CD 1 ATOM 5711 C CE . LYS A 1 711 ? 19.074 74.600 -26.016 1.00 22.43 ? 711 LYS A CE 1 ATOM 5712 N NZ . LYS A 1 711 ? 17.753 73.862 -26.168 1.00 23.70 ? 711 LYS A NZ 1 ATOM 5713 N N . PHE A 1 712 ? 23.619 76.232 -22.842 1.00 10.88 ? 712 PHE A N 1 ATOM 5714 C CA . PHE A 1 712 ? 23.860 76.563 -21.466 1.00 11.18 ? 712 PHE A CA 1 ATOM 5715 C C . PHE A 1 712 ? 22.537 76.899 -20.788 1.00 10.14 ? 712 PHE A C 1 ATOM 5716 O O . PHE A 1 712 ? 21.721 77.652 -21.337 1.00 11.44 ? 712 PHE A O 1 ATOM 5717 C CB . PHE A 1 712 ? 24.884 77.731 -21.328 1.00 10.70 ? 712 PHE A CB 1 ATOM 5718 C CG . PHE A 1 712 ? 26.298 77.322 -21.640 1.00 10.66 ? 712 PHE A CG 1 ATOM 5719 C CD1 . PHE A 1 712 ? 26.770 77.392 -22.943 1.00 11.01 ? 712 PHE A CD1 1 ATOM 5720 C CD2 . PHE A 1 712 ? 27.140 76.822 -20.637 1.00 9.91 ? 712 PHE A CD2 1 ATOM 5721 C CE1 . PHE A 1 712 ? 28.065 76.970 -23.261 1.00 10.18 ? 712 PHE A CE1 1 ATOM 5722 C CE2 . PHE A 1 712 ? 28.401 76.415 -20.944 1.00 10.01 ? 712 PHE A CE2 1 ATOM 5723 C CZ . PHE A 1 712 ? 28.868 76.480 -22.226 1.00 10.74 ? 712 PHE A CZ 1 ATOM 5724 N N . LEU A 1 713 ? 22.330 76.340 -19.608 1.00 9.93 ? 713 LEU A N 1 ATOM 5725 C CA . LEU A 1 713 ? 21.079 76.545 -18.856 1.00 9.87 ? 713 LEU A CA 1 ATOM 5726 C C . LEU A 1 713 ? 21.401 76.814 -17.412 1.00 10.22 ? 713 LEU A C 1 ATOM 5727 O O . LEU A 1 713 ? 22.586 76.709 -16.977 1.00 11.39 ? 713 LEU A O 1 ATOM 5728 C CB . LEU A 1 713 ? 20.144 75.316 -18.963 1.00 10.97 ? 713 LEU A CB 1 ATOM 5729 C CG . LEU A 1 713 ? 19.832 74.883 -20.396 1.00 11.07 ? 713 LEU A CG 1 ATOM 5730 C CD1 . LEU A 1 713 ? 20.702 73.678 -20.821 1.00 12.34 ? 713 LEU A CD1 1 ATOM 5731 C CD2 . LEU A 1 713 ? 18.334 74.368 -20.494 1.00 12.21 ? 713 LEU A CD2 1 ATOM 5732 N N . LYS A 1 714 ? 20.401 77.181 -16.632 1.00 11.23 ? 714 LYS A N 1 ATOM 5733 C CA . LYS A 1 714 ? 20.597 77.470 -15.245 1.00 12.52 ? 714 LYS A CA 1 ATOM 5734 C C . LYS A 1 714 ? 19.583 76.822 -14.354 1.00 12.05 ? 714 LYS A C 1 ATOM 5735 O O . LYS A 1 714 ? 18.375 76.743 -14.689 1.00 13.02 ? 714 LYS A O 1 ATOM 5736 C CB . LYS A 1 714 ? 20.575 78.972 -14.982 1.00 17.03 ? 714 LYS A CB 1 ATOM 5737 C CG . LYS A 1 714 ? 19.457 79.695 -15.629 1.00 22.02 ? 714 LYS A CG 1 ATOM 5738 C CD . LYS A 1 714 ? 19.486 81.188 -15.201 1.00 25.36 ? 714 LYS A CD 1 ATOM 5739 C CE . LYS A 1 714 ? 20.830 81.855 -15.501 1.00 26.61 ? 714 LYS A CE 1 ATOM 5740 N NZ . LYS A 1 714 ? 20.888 83.356 -15.251 1.00 29.36 ? 714 LYS A NZ 1 ATOM 5741 N N . TYR A 1 715 ? 20.078 76.279 -13.248 1.00 9.81 ? 715 TYR A N 1 ATOM 5742 C CA . TYR A 1 715 ? 19.219 75.765 -12.206 1.00 10.12 ? 715 TYR A CA 1 ATOM 5743 C C . TYR A 1 715 ? 19.181 76.786 -11.069 1.00 11.39 ? 715 TYR A C 1 ATOM 5744 O O . TYR A 1 715 ? 20.154 77.534 -10.819 1.00 12.25 ? 715 TYR A O 1 ATOM 5745 C CB . TYR A 1 715 ? 19.758 74.450 -11.598 1.00 10.48 ? 715 TYR A CB 1 ATOM 5746 C CG . TYR A 1 715 ? 19.685 73.245 -12.459 1.00 9.29 ? 715 TYR A CG 1 ATOM 5747 C CD1 . TYR A 1 715 ? 18.513 72.498 -12.522 1.00 9.63 ? 715 TYR A CD1 1 ATOM 5748 C CD2 . TYR A 1 715 ? 20.806 72.788 -13.231 1.00 9.47 ? 715 TYR A CD2 1 ATOM 5749 C CE1 . TYR A 1 715 ? 18.458 71.358 -13.295 1.00 10.55 ? 715 TYR A CE1 1 ATOM 5750 C CE2 . TYR A 1 715 ? 20.724 71.644 -14.013 1.00 9.61 ? 715 TYR A CE2 1 ATOM 5751 C CZ . TYR A 1 715 ? 19.538 70.913 -14.039 1.00 9.42 ? 715 TYR A CZ 1 ATOM 5752 O OH . TYR A 1 715 ? 19.398 69.787 -14.751 1.00 10.47 ? 715 TYR A OH 1 ATOM 5753 N N . GLY A 1 716 ? 18.068 76.833 -10.357 1.00 11.64 ? 716 GLY A N 1 ATOM 5754 C CA . GLY A 1 716 ? 17.916 77.726 -9.236 1.00 11.83 ? 716 GLY A CA 1 ATOM 5755 C C . GLY A 1 716 ? 17.794 76.952 -7.931 1.00 11.97 ? 716 GLY A C 1 ATOM 5756 O O . GLY A 1 716 ? 18.112 75.731 -7.850 1.00 12.69 ? 716 GLY A O 1 ATOM 5757 N N . VAL A 1 717 ? 17.317 77.640 -6.915 1.00 12.29 ? 717 VAL A N 1 ATOM 5758 C CA . VAL A 1 717 ? 17.199 77.118 -5.579 1.00 13.82 ? 717 VAL A CA 1 ATOM 5759 C C . VAL A 1 717 ? 15.743 77.295 -5.142 1.00 13.25 ? 717 VAL A C 1 ATOM 5760 O O . VAL A 1 717 ? 15.090 78.263 -5.556 1.00 15.66 ? 717 VAL A O 1 ATOM 5761 C CB . VAL A 1 717 ? 18.170 77.915 -4.657 1.00 13.86 ? 717 VAL A CB 1 ATOM 5762 C CG1 . VAL A 1 717 ? 18.001 77.513 -3.199 1.00 16.53 ? 717 VAL A CG1 1 ATOM 5763 C CG2 . VAL A 1 717 ? 19.637 77.698 -5.156 1.00 13.84 ? 717 VAL A CG2 1 ATOM 5764 N N . ARG A 1 718 ? 15.278 76.408 -4.273 1.00 13.76 ? 718 ARG A N 1 ATOM 5765 C CA . ARG A 1 718 ? 13.890 76.456 -3.808 1.00 14.30 ? 718 ARG A CA 1 ATOM 5766 C C . ARG A 1 718 ? 13.670 77.611 -2.871 1.00 16.69 ? 718 ARG A C 1 ATOM 5767 O O . ARG A 1 718 ? 14.513 77.950 -2.050 1.00 19.22 ? 718 ARG A O 1 ATOM 5768 C CB . ARG A 1 718 ? 13.512 75.146 -3.100 1.00 13.46 ? 718 ARG A CB 1 ATOM 5769 C CG . ARG A 1 718 ? 13.540 73.957 -4.046 1.00 13.37 ? 718 ARG A CG 1 ATOM 5770 C CD . ARG A 1 718 ? 13.541 72.621 -3.334 1.00 13.52 ? 718 ARG A CD 1 ATOM 5771 N NE . ARG A 1 718 ? 13.828 71.605 -4.328 1.00 13.95 ? 718 ARG A NE 1 ATOM 5772 C CZ . ARG A 1 718 ? 13.780 70.288 -4.104 1.00 13.22 ? 718 ARG A CZ 1 ATOM 5773 N NH1 . ARG A 1 718 ? 13.449 69.843 -2.899 1.00 13.16 ? 718 ARG A NH1 1 ATOM 5774 N NH2 . ARG A 1 718 ? 14.088 69.464 -5.106 1.00 13.86 ? 718 ARG A NH2 1 ATOM 5775 N N . SER A 1 719 ? 12.488 78.205 -2.997 1.00 17.71 ? 719 SER A N 1 ATOM 5776 C CA . SER A 1 719 ? 12.151 79.325 -2.137 1.00 20.77 ? 719 SER A CA 1 ATOM 5777 C C . SER A 1 719 ? 11.394 78.827 -0.903 1.00 22.11 ? 719 SER A C 1 ATOM 5778 O O . SER A 1 719 ? 11.133 79.597 0.002 1.00 23.82 ? 719 SER A O 1 ATOM 5779 C CB . SER A 1 719 ? 11.307 80.343 -2.919 1.00 21.67 ? 719 SER A CB 1 ATOM 5780 O OG . SER A 1 719 ? 10.142 79.724 -3.391 1.00 24.24 ? 719 SER A OG 1 ATOM 5781 N N . HIS A 1 720 ? 10.990 77.562 -0.907 1.00 23.61 ? 720 HIS A N 1 ATOM 5782 C CA . HIS A 1 720 ? 10.351 76.952 0.237 1.00 24.32 ? 720 HIS A CA 1 ATOM 5783 C C . HIS A 1 720 ? 10.978 75.548 0.364 1.00 23.16 ? 720 HIS A C 1 ATOM 5784 O O . HIS A 1 720 ? 11.306 74.905 -0.642 1.00 23.07 ? 720 HIS A O 1 ATOM 5785 C CB . HIS A 1 720 ? 8.807 76.911 0.081 1.00 28.56 ? 720 HIS A CB 1 ATOM 5786 C CG . HIS A 1 720 ? 8.313 76.157 -1.115 1.00 32.77 ? 720 HIS A CG 1 ATOM 5787 N ND1 . HIS A 1 720 ? 7.767 74.890 -1.022 1.00 34.94 ? 720 HIS A ND1 1 ATOM 5788 C CD2 . HIS A 1 720 ? 8.240 76.503 -2.427 1.00 34.81 ? 720 HIS A CD2 1 ATOM 5789 C CE1 . HIS A 1 720 ? 7.380 74.490 -2.226 1.00 35.27 ? 720 HIS A CE1 1 ATOM 5790 N NE2 . HIS A 1 720 ? 7.655 75.450 -3.095 1.00 35.71 ? 720 HIS A NE2 1 ATOM 5791 N N . GLY A 1 721 ? 11.159 75.101 1.594 1.00 21.90 ? 721 GLY A N 1 ATOM 5792 C CA . GLY A 1 721 ? 11.751 73.784 1.800 1.00 21.16 ? 721 GLY A CA 1 ATOM 5793 C C . GLY A 1 721 ? 13.263 73.844 1.948 1.00 20.30 ? 721 GLY A C 1 ATOM 5794 O O . GLY A 1 721 ? 13.857 74.853 2.327 1.00 20.43 ? 721 GLY A O 1 ATOM 5795 N N . ASP A 1 722 ? 13.903 72.744 1.601 1.00 17.76 ? 722 ASP A N 1 ATOM 5796 C CA . ASP A 1 722 ? 15.350 72.660 1.794 1.00 16.28 ? 722 ASP A CA 1 ATOM 5797 C C . ASP A 1 722 ? 16.126 73.339 0.689 1.00 14.98 ? 722 ASP A C 1 ATOM 5798 O O . ASP A 1 722 ? 15.771 73.271 -0.478 1.00 14.90 ? 722 ASP A O 1 ATOM 5799 C CB . ASP A 1 722 ? 15.767 71.202 1.899 1.00 15.57 ? 722 ASP A CB 1 ATOM 5800 C CG . ASP A 1 722 ? 15.173 70.480 3.135 1.00 15.78 ? 722 ASP A CG 1 ATOM 5801 O OD1 . ASP A 1 722 ? 14.977 71.087 4.223 1.00 18.09 ? 722 ASP A OD1 1 ATOM 5802 O OD2 . ASP A 1 722 ? 14.929 69.266 3.007 1.00 16.77 ? 722 ASP A OD2 1 ATOM 5803 N N . ARG A 1 723 ? 17.196 74.011 1.101 1.00 13.98 ? 723 ARG A N 1 ATOM 5804 C CA . ARG A 1 723 ? 18.028 74.734 0.154 1.00 14.06 ? 723 ARG A CA 1 ATOM 5805 C C . ARG A 1 723 ? 19.308 74.010 -0.237 1.00 11.82 ? 723 ARG A C 1 ATOM 5806 O O . ARG A 1 723 ? 19.954 73.398 0.607 1.00 12.33 ? 723 ARG A O 1 ATOM 5807 C CB . ARG A 1 723 ? 18.461 76.082 0.769 1.00 16.34 ? 723 ARG A CB 1 ATOM 5808 C CG . ARG A 1 723 ? 17.365 77.206 0.765 1.00 23.04 ? 723 ARG A CG 1 ATOM 5809 C CD . ARG A 1 723 ? 16.168 76.830 1.620 1.00 28.87 ? 723 ARG A CD 1 ATOM 5810 N NE . ARG A 1 723 ? 15.019 77.755 1.539 1.00 34.24 ? 723 ARG A NE 1 ATOM 5811 C CZ . ARG A 1 723 ? 15.105 79.081 1.590 1.00 36.25 ? 723 ARG A CZ 1 ATOM 5812 N NH1 . ARG A 1 723 ? 16.291 79.684 1.700 1.00 38.01 ? 723 ARG A NH1 1 ATOM 5813 N NH2 . ARG A 1 723 ? 13.995 79.810 1.598 1.00 37.32 ? 723 ARG A NH2 1 ATOM 5814 N N . SER A 1 724 ? 19.621 74.117 -1.537 1.00 10.90 ? 724 SER A N 1 ATOM 5815 C CA . SER A 1 724 ? 20.910 73.642 -2.014 1.00 10.68 ? 724 SER A CA 1 ATOM 5816 C C . SER A 1 724 ? 22.027 74.369 -1.279 1.00 11.18 ? 724 SER A C 1 ATOM 5817 O O . SER A 1 724 ? 21.917 75.552 -0.911 1.00 12.84 ? 724 SER A O 1 ATOM 5818 C CB . SER A 1 724 ? 21.101 73.971 -3.470 1.00 11.20 ? 724 SER A CB 1 ATOM 5819 O OG . SER A 1 724 ? 20.040 73.398 -4.204 1.00 10.58 ? 724 SER A OG 1 ATOM 5820 N N . GLY A 1 725 ? 23.147 73.654 -1.087 1.00 10.24 ? 725 GLY A N 1 ATOM 5821 C CA . GLY A 1 725 ? 24.333 74.227 -0.435 1.00 9.70 ? 725 GLY A CA 1 ATOM 5822 C C . GLY A 1 725 ? 25.552 73.496 -1.008 1.00 9.12 ? 725 GLY A C 1 ATOM 5823 O O . GLY A 1 725 ? 25.455 72.827 -2.035 1.00 9.34 ? 725 GLY A O 1 ATOM 5824 N N . ALA A 1 726 ? 26.683 73.574 -0.327 1.00 8.68 ? 726 ALA A N 1 ATOM 5825 C CA . ALA A 1 726 ? 27.910 72.934 -0.837 1.00 8.29 ? 726 ALA A CA 1 ATOM 5826 C C . ALA A 1 726 ? 27.758 71.432 -1.044 1.00 8.54 ? 726 ALA A C 1 ATOM 5827 O O . ALA A 1 726 ? 28.416 70.867 -1.916 1.00 8.09 ? 726 ALA A O 1 ATOM 5828 C CB . ALA A 1 726 ? 29.071 73.185 0.146 1.00 9.46 ? 726 ALA A CB 1 ATOM 5829 N N . TYR A 1 727 ? 26.951 70.780 -0.194 1.00 8.44 ? 727 TYR A N 1 ATOM 5830 C CA . TYR A 1 727 ? 26.759 69.323 -0.327 1.00 7.65 ? 727 TYR A CA 1 ATOM 5831 C C . TYR A 1 727 ? 25.581 68.927 -1.186 1.00 7.45 ? 727 TYR A C 1 ATOM 5832 O O . TYR A 1 727 ? 25.715 68.090 -2.095 1.00 8.37 ? 727 TYR A O 1 ATOM 5833 C CB . TYR A 1 727 ? 26.551 68.661 1.044 1.00 8.84 ? 727 TYR A CB 1 ATOM 5834 C CG . TYR A 1 727 ? 27.674 68.880 2.060 1.00 8.70 ? 727 TYR A CG 1 ATOM 5835 C CD1 . TYR A 1 727 ? 27.683 69.993 2.898 1.00 8.92 ? 727 TYR A CD1 1 ATOM 5836 C CD2 . TYR A 1 727 ? 28.715 67.970 2.183 1.00 8.28 ? 727 TYR A CD2 1 ATOM 5837 C CE1 . TYR A 1 727 ? 28.710 70.199 3.852 1.00 9.07 ? 727 TYR A CE1 1 ATOM 5838 C CE2 . TYR A 1 727 ? 29.744 68.148 3.126 1.00 8.85 ? 727 TYR A CE2 1 ATOM 5839 C CZ . TYR A 1 727 ? 29.740 69.247 3.950 1.00 8.84 ? 727 TYR A CZ 1 ATOM 5840 O OH . TYR A 1 727 ? 30.756 69.393 4.884 1.00 10.05 ? 727 TYR A OH 1 ATOM 5841 N N . LEU A 1 728 ? 24.430 69.542 -0.913 1.00 8.36 ? 728 LEU A N 1 ATOM 5842 C CA . LEU A 1 728 ? 23.184 69.140 -1.565 1.00 7.83 ? 728 LEU A CA 1 ATOM 5843 C C . LEU A 1 728 ? 22.800 69.884 -2.824 1.00 8.40 ? 728 LEU A C 1 ATOM 5844 O O . LEU A 1 728 ? 23.001 71.099 -2.920 1.00 9.16 ? 728 LEU A O 1 ATOM 5845 C CB . LEU A 1 728 ? 22.019 69.352 -0.570 1.00 10.35 ? 728 LEU A CB 1 ATOM 5846 C CG . LEU A 1 728 ? 22.199 68.755 0.813 1.00 8.41 ? 728 LEU A CG 1 ATOM 5847 C CD1 . LEU A 1 728 ? 20.844 68.999 1.593 1.00 11.51 ? 728 LEU A CD1 1 ATOM 5848 C CD2 . LEU A 1 728 ? 22.514 67.297 0.734 1.00 10.38 ? 728 LEU A CD2 1 ATOM 5849 N N . PHE A 1 729 ? 22.236 69.162 -3.784 1.00 9.44 ? 729 PHE A N 1 ATOM 5850 C CA . PHE A 1 729 ? 21.688 69.751 -4.990 1.00 9.16 ? 729 PHE A CA 1 ATOM 5851 C C . PHE A 1 729 ? 20.153 69.553 -4.866 1.00 9.75 ? 729 PHE A C 1 ATOM 5852 O O . PHE A 1 729 ? 19.647 68.416 -4.944 1.00 10.28 ? 729 PHE A O 1 ATOM 5853 C CB . PHE A 1 729 ? 22.223 69.034 -6.216 1.00 8.58 ? 729 PHE A CB 1 ATOM 5854 C CG . PHE A 1 729 ? 21.701 69.532 -7.552 1.00 8.03 ? 729 PHE A CG 1 ATOM 5855 C CD1 . PHE A 1 729 ? 21.375 70.882 -7.773 1.00 8.88 ? 729 PHE A CD1 1 ATOM 5856 C CD2 . PHE A 1 729 ? 21.614 68.632 -8.602 1.00 8.48 ? 729 PHE A CD2 1 ATOM 5857 C CE1 . PHE A 1 729 ? 20.968 71.278 -9.073 1.00 8.92 ? 729 PHE A CE1 1 ATOM 5858 C CE2 . PHE A 1 729 ? 21.203 69.033 -9.886 1.00 8.46 ? 729 PHE A CE2 1 ATOM 5859 C CZ . PHE A 1 729 ? 20.888 70.355 -10.103 1.00 8.99 ? 729 PHE A CZ 1 ATOM 5860 N N . LEU A 1 730 ? 19.452 70.683 -4.680 1.00 9.57 ? 730 LEU A N 1 ATOM 5861 C CA . LEU A 1 730 ? 17.966 70.658 -4.528 1.00 10.19 ? 730 LEU A CA 1 ATOM 5862 C C . LEU A 1 730 ? 17.374 71.679 -5.501 1.00 9.66 ? 730 LEU A C 1 ATOM 5863 O O . LEU A 1 730 ? 16.937 72.768 -5.087 1.00 10.53 ? 730 LEU A O 1 ATOM 5864 C CB . LEU A 1 730 ? 17.656 71.001 -3.076 1.00 10.08 ? 730 LEU A CB 1 ATOM 5865 C CG . LEU A 1 730 ? 18.047 69.918 -2.072 1.00 10.54 ? 730 LEU A CG 1 ATOM 5866 C CD1 . LEU A 1 730 ? 18.034 70.488 -0.684 1.00 12.92 ? 730 LEU A CD1 1 ATOM 5867 C CD2 . LEU A 1 730 ? 17.040 68.751 -2.224 1.00 13.49 ? 730 LEU A CD2 1 ATOM 5868 N N . PRO A 1 731 ? 17.411 71.368 -6.781 1.00 9.80 ? 731 PRO A N 1 ATOM 5869 C CA . PRO A 1 731 ? 16.887 72.326 -7.780 1.00 11.26 ? 731 PRO A CA 1 ATOM 5870 C C . PRO A 1 731 ? 15.442 72.668 -7.678 1.00 11.47 ? 731 PRO A C 1 ATOM 5871 O O . PRO A 1 731 ? 14.661 71.860 -7.189 1.00 12.20 ? 731 PRO A O 1 ATOM 5872 C CB . PRO A 1 731 ? 17.214 71.681 -9.118 1.00 11.29 ? 731 PRO A CB 1 ATOM 5873 C CG . PRO A 1 731 ? 17.192 70.151 -8.779 1.00 11.52 ? 731 PRO A CG 1 ATOM 5874 C CD . PRO A 1 731 ? 17.803 70.083 -7.399 1.00 10.90 ? 731 PRO A CD 1 ATOM 5875 N N . ASN A 1 732 ? 15.095 73.861 -8.142 1.00 12.34 ? 732 ASN A N 1 ATOM 5876 C CA . ASN A 1 732 ? 13.656 74.249 -8.121 1.00 13.62 ? 732 ASN A CA 1 ATOM 5877 C C . ASN A 1 732 ? 13.111 73.956 -9.518 1.00 13.51 ? 732 ASN A C 1 ATOM 5878 O O . ASN A 1 732 ? 12.586 74.844 -10.241 1.00 16.14 ? 732 ASN A O 1 ATOM 5879 C CB . ASN A 1 732 ? 13.522 75.735 -7.775 1.00 16.28 ? 732 ASN A CB 1 ATOM 5880 C CG . ASN A 1 732 ? 14.187 76.627 -8.789 1.00 18.15 ? 732 ASN A CG 1 ATOM 5881 O OD1 . ASN A 1 732 ? 15.187 76.265 -9.391 1.00 18.63 ? 732 ASN A OD1 1 ATOM 5882 N ND2 . ASN A 1 732 ? 13.612 77.832 -9.009 1.00 20.39 ? 732 ASN A ND2 1 ATOM 5883 N N . GLY A 1 733 ? 13.241 72.703 -9.936 1.00 13.05 ? 733 GLY A N 1 ATOM 5884 C CA . GLY A 1 733 ? 12.771 72.217 -11.222 1.00 14.17 ? 733 GLY A CA 1 ATOM 5885 C C . GLY A 1 733 ? 13.865 72.103 -12.279 1.00 12.68 ? 733 GLY A C 1 ATOM 5886 O O . GLY A 1 733 ? 15.046 72.440 -12.004 1.00 13.00 ? 733 GLY A O 1 ATOM 5887 N N . PRO A 1 734 ? 13.531 71.666 -13.488 1.00 11.83 ? 734 PRO A N 1 ATOM 5888 C CA . PRO A 1 734 ? 14.455 71.519 -14.619 1.00 13.14 ? 734 PRO A CA 1 ATOM 5889 C C . PRO A 1 734 ? 15.074 72.889 -14.909 1.00 12.27 ? 734 PRO A C 1 ATOM 5890 O O . PRO A 1 734 ? 14.503 73.965 -14.642 1.00 13.15 ? 734 PRO A O 1 ATOM 5891 C CB . PRO A 1 734 ? 13.561 71.072 -15.784 1.00 14.09 ? 734 PRO A CB 1 ATOM 5892 C CG . PRO A 1 734 ? 12.412 70.413 -15.075 1.00 16.82 ? 734 PRO A CG 1 ATOM 5893 C CD . PRO A 1 734 ? 12.184 71.150 -13.822 1.00 14.12 ? 734 PRO A CD 1 ATOM 5894 N N . ALA A 1 735 ? 16.259 72.839 -15.509 1.00 11.62 ? 735 ALA A N 1 ATOM 5895 C CA . ALA A 1 735 ? 16.983 74.058 -15.795 1.00 12.85 ? 735 ALA A CA 1 ATOM 5896 C C . ALA A 1 735 ? 16.279 74.893 -16.879 1.00 13.09 ? 735 ALA A C 1 ATOM 5897 O O . ALA A 1 735 ? 15.585 74.355 -17.723 1.00 14.06 ? 735 ALA A O 1 ATOM 5898 C CB . ALA A 1 735 ? 18.435 73.659 -16.227 1.00 12.15 ? 735 ALA A CB 1 ATOM 5899 N N . SER A 1 736 ? 16.544 76.202 -16.869 1.00 13.53 ? 736 SER A N 1 ATOM 5900 C CA . SER A 1 736 ? 15.957 77.145 -17.846 1.00 15.20 ? 736 SER A CA 1 ATOM 5901 C C . SER A 1 736 ? 17.107 77.657 -18.686 1.00 15.15 ? 736 SER A C 1 ATOM 5902 O O . SER A 1 736 ? 18.175 77.858 -18.164 1.00 13.99 ? 736 SER A O 1 ATOM 5903 C CB . SER A 1 736 ? 15.346 78.321 -17.099 1.00 17.53 ? 736 SER A CB 1 ATOM 5904 O OG . SER A 1 736 ? 14.444 77.858 -16.121 1.00 22.82 ? 736 SER A OG 1 ATOM 5905 N N . PRO A 1 737 ? 16.915 77.900 -19.977 1.00 15.77 ? 737 PRO A N 1 ATOM 5906 C CA . PRO A 1 737 ? 18.036 78.391 -20.818 1.00 17.33 ? 737 PRO A CA 1 ATOM 5907 C C . PRO A 1 737 ? 18.614 79.715 -20.397 1.00 16.63 ? 737 PRO A C 1 ATOM 5908 O O . PRO A 1 737 ? 17.890 80.582 -19.904 1.00 17.96 ? 737 PRO A O 1 ATOM 5909 C CB . PRO A 1 737 ? 17.442 78.500 -22.223 1.00 18.02 ? 737 PRO A CB 1 ATOM 5910 C CG . PRO A 1 737 ? 16.216 77.602 -22.178 1.00 18.81 ? 737 PRO A CG 1 ATOM 5911 C CD . PRO A 1 737 ? 15.683 77.672 -20.760 1.00 17.68 ? 737 PRO A CD 1 ATOM 5912 N N . VAL A 1 738 ? 19.948 79.851 -20.501 1.00 16.46 ? 738 VAL A N 1 ATOM 5913 C CA . VAL A 1 738 ? 20.552 81.148 -20.185 1.00 16.36 ? 738 VAL A CA 1 ATOM 5914 C C . VAL A 1 738 ? 20.145 82.076 -21.358 1.00 16.97 ? 738 VAL A C 1 ATOM 5915 O O . VAL A 1 738 ? 20.203 81.663 -22.508 1.00 16.41 ? 738 VAL A O 1 ATOM 5916 C CB . VAL A 1 738 ? 22.064 81.008 -20.144 1.00 15.09 ? 738 VAL A CB 1 ATOM 5917 C CG1 . VAL A 1 738 ? 22.720 82.429 -20.052 1.00 16.23 ? 738 VAL A CG1 1 ATOM 5918 C CG2 . VAL A 1 738 ? 22.481 80.165 -18.910 1.00 14.96 ? 738 VAL A CG2 1 ATOM 5919 N N . GLU A 1 739 ? 19.719 83.317 -21.085 1.00 18.18 ? 739 GLU A N 1 ATOM 5920 C CA . GLU A 1 739 ? 19.349 84.236 -22.191 1.00 19.42 ? 739 GLU A CA 1 ATOM 5921 C C . GLU A 1 739 ? 20.660 84.752 -22.727 1.00 18.03 ? 739 GLU A C 1 ATOM 5922 O O . GLU A 1 739 ? 21.441 85.386 -22.003 1.00 19.36 ? 739 GLU A O 1 ATOM 5923 C CB . GLU A 1 739 ? 18.496 85.397 -21.688 1.00 22.09 ? 739 GLU A CB 1 ATOM 5924 C CG . GLU A 1 739 ? 17.024 85.031 -21.536 1.00 28.54 ? 739 GLU A CG 1 ATOM 5925 C CD . GLU A 1 739 ? 16.145 86.228 -21.136 1.00 32.01 ? 739 GLU A CD 1 ATOM 5926 O OE1 . GLU A 1 739 ? 16.612 87.389 -21.204 1.00 34.13 ? 739 GLU A OE1 1 ATOM 5927 O OE2 . GLU A 1 739 ? 14.970 85.986 -20.763 1.00 34.65 ? 739 GLU A OE2 1 ATOM 5928 N N . LEU A 1 740 ? 20.894 84.461 -23.996 1.00 17.91 ? 740 LEU A N 1 ATOM 5929 C CA . LEU A 1 740 ? 22.175 84.794 -24.615 1.00 18.34 ? 740 LEU A CA 1 ATOM 5930 C C . LEU A 1 740 ? 22.361 86.155 -25.213 1.00 19.39 ? 740 LEU A C 1 ATOM 5931 O O . LEU A 1 740 ? 23.490 86.561 -25.378 1.00 19.38 ? 740 LEU A O 1 ATOM 5932 C CB . LEU A 1 740 ? 22.522 83.750 -25.673 1.00 18.56 ? 740 LEU A CB 1 ATOM 5933 C CG . LEU A 1 740 ? 22.487 82.282 -25.217 1.00 18.38 ? 740 LEU A CG 1 ATOM 5934 C CD1 . LEU A 1 740 ? 22.967 81.442 -26.347 1.00 19.29 ? 740 LEU A CD1 1 ATOM 5935 C CD2 . LEU A 1 740 ? 23.409 82.042 -23.990 1.00 17.85 ? 740 LEU A CD2 1 ATOM 5936 N N . GLY A 1 741 ? 21.268 86.850 -25.526 1.00 19.80 ? 741 GLY A N 1 ATOM 5937 C CA . GLY A 1 741 ? 21.407 88.160 -26.158 1.00 20.11 ? 741 GLY A CA 1 ATOM 5938 C C . GLY A 1 741 ? 21.965 87.931 -27.564 1.00 19.67 ? 741 GLY A C 1 ATOM 5939 O O . GLY A 1 741 ? 21.622 86.953 -28.210 1.00 19.93 ? 741 GLY A O 1 ATOM 5940 N N . GLN A 1 742 ? 22.793 88.847 -28.079 1.00 19.92 ? 742 GLN A N 1 ATOM 5941 C CA . GLN A 1 742 ? 23.405 88.646 -29.401 1.00 19.74 ? 742 GLN A CA 1 ATOM 5942 C C . GLN A 1 742 ? 24.910 88.644 -29.051 1.00 18.21 ? 742 GLN A C 1 ATOM 5943 O O . GLN A 1 742 ? 25.593 89.662 -29.109 1.00 19.46 ? 742 GLN A O 1 ATOM 5944 C CB . GLN A 1 742 ? 23.081 89.810 -30.333 1.00 22.59 ? 742 GLN A CB 1 ATOM 5945 C CG . GLN A 1 742 ? 23.506 89.518 -31.751 1.00 28.06 ? 742 GLN A CG 1 ATOM 5946 C CD . GLN A 1 742 ? 22.824 90.410 -32.777 1.00 30.55 ? 742 GLN A CD 1 ATOM 5947 O OE1 . GLN A 1 742 ? 23.069 90.267 -33.975 1.00 31.64 ? 742 GLN A OE1 1 ATOM 5948 N NE2 . GLN A 1 742 ? 21.948 91.331 -32.311 1.00 32.47 ? 742 GLN A NE2 1 ATOM 5949 N N . PRO A 1 743 ? 25.440 87.480 -28.679 1.00 16.66 ? 743 PRO A N 1 ATOM 5950 C CA . PRO A 1 743 ? 26.858 87.457 -28.300 1.00 15.68 ? 743 PRO A CA 1 ATOM 5951 C C . PRO A 1 743 ? 27.890 87.661 -29.397 1.00 14.72 ? 743 PRO A C 1 ATOM 5952 O O . PRO A 1 743 ? 27.658 87.399 -30.588 1.00 16.59 ? 743 PRO A O 1 ATOM 5953 C CB . PRO A 1 743 ? 27.000 86.102 -27.613 1.00 15.75 ? 743 PRO A CB 1 ATOM 5954 C CG . PRO A 1 743 ? 26.010 85.240 -28.331 1.00 15.58 ? 743 PRO A CG 1 ATOM 5955 C CD . PRO A 1 743 ? 24.820 86.146 -28.650 1.00 15.34 ? 743 PRO A CD 1 ATOM 5956 N N . VAL A 1 744 ? 29.068 88.135 -28.987 1.00 12.54 ? 744 VAL A N 1 ATOM 5957 C CA . VAL A 1 744 ? 30.163 88.327 -29.945 1.00 12.05 ? 744 VAL A CA 1 ATOM 5958 C C . VAL A 1 744 ? 30.850 86.980 -30.168 1.00 11.38 ? 744 VAL A C 1 ATOM 5959 O O . VAL A 1 744 ? 31.183 86.270 -29.185 1.00 12.26 ? 744 VAL A O 1 ATOM 5960 C CB . VAL A 1 744 ? 31.182 89.335 -29.404 1.00 12.06 ? 744 VAL A CB 1 ATOM 5961 C CG1 . VAL A 1 744 ? 32.312 89.551 -30.380 1.00 12.70 ? 744 VAL A CG1 1 ATOM 5962 C CG2 . VAL A 1 744 ? 30.442 90.679 -29.105 1.00 14.37 ? 744 VAL A CG2 1 ATOM 5963 N N . VAL A 1 745 ? 31.060 86.621 -31.417 1.00 11.01 ? 745 VAL A N 1 ATOM 5964 C CA . VAL A 1 745 ? 31.696 85.382 -31.821 1.00 10.22 ? 745 VAL A CA 1 ATOM 5965 C C . VAL A 1 745 ? 32.987 85.631 -32.565 1.00 10.83 ? 745 VAL A C 1 ATOM 5966 O O . VAL A 1 745 ? 33.039 86.457 -33.499 1.00 11.83 ? 745 VAL A O 1 ATOM 5967 C CB . VAL A 1 745 ? 30.720 84.521 -32.721 1.00 10.92 ? 745 VAL A CB 1 ATOM 5968 C CG1 . VAL A 1 745 ? 31.411 83.203 -33.135 1.00 11.53 ? 745 VAL A CG1 1 ATOM 5969 C CG2 . VAL A 1 745 ? 29.429 84.227 -31.968 1.00 11.94 ? 745 VAL A CG2 1 ATOM 5970 N N . LEU A 1 746 ? 34.061 84.935 -32.214 1.00 9.71 ? 746 LEU A N 1 ATOM 5971 C CA . LEU A 1 746 ? 35.379 85.059 -32.828 1.00 9.40 ? 746 LEU A CA 1 ATOM 5972 C C . LEU A 1 746 ? 35.788 83.762 -33.476 1.00 10.07 ? 746 LEU A C 1 ATOM 5973 O O . LEU A 1 746 ? 35.880 82.709 -32.787 1.00 10.29 ? 746 LEU A O 1 ATOM 5974 C CB . LEU A 1 746 ? 36.412 85.467 -31.774 1.00 11.08 ? 746 LEU A CB 1 ATOM 5975 C CG . LEU A 1 746 ? 37.868 85.480 -32.253 1.00 11.75 ? 746 LEU A CG 1 ATOM 5976 C CD1 . LEU A 1 746 ? 38.112 86.546 -33.283 1.00 13.02 ? 746 LEU A CD1 1 ATOM 5977 C CD2 . LEU A 1 746 ? 38.741 85.760 -31.035 1.00 14.37 ? 746 LEU A CD2 1 ATOM 5978 N N . VAL A 1 747 ? 36.063 83.789 -34.762 1.00 9.90 ? 747 VAL A N 1 ATOM 5979 C CA . VAL A 1 747 ? 36.471 82.606 -35.509 1.00 10.05 ? 747 VAL A CA 1 ATOM 5980 C C . VAL A 1 747 ? 37.890 82.753 -35.930 1.00 10.73 ? 747 VAL A C 1 ATOM 5981 O O . VAL A 1 747 ? 38.264 83.727 -36.628 1.00 12.20 ? 747 VAL A O 1 ATOM 5982 C CB . VAL A 1 747 ? 35.590 82.400 -36.754 1.00 10.62 ? 747 VAL A CB 1 ATOM 5983 C CG1 . VAL A 1 747 ? 35.948 81.136 -37.459 1.00 12.06 ? 747 VAL A CG1 1 ATOM 5984 C CG2 . VAL A 1 747 ? 34.135 82.352 -36.368 1.00 11.09 ? 747 VAL A CG2 1 ATOM 5985 N N . THR A 1 748 ? 38.764 81.841 -35.531 1.00 10.51 ? 748 THR A N 1 ATOM 5986 C CA . THR A 1 748 ? 40.153 81.880 -35.945 1.00 11.13 ? 748 THR A CA 1 ATOM 5987 C C . THR A 1 748 ? 40.356 80.649 -36.765 1.00 10.96 ? 748 THR A C 1 ATOM 5988 O O . THR A 1 748 ? 40.039 79.543 -36.290 1.00 12.82 ? 748 THR A O 1 ATOM 5989 C CB . THR A 1 748 ? 41.079 81.902 -34.703 1.00 12.13 ? 748 THR A CB 1 ATOM 5990 O OG1 . THR A 1 748 ? 40.820 83.111 -33.966 1.00 13.28 ? 748 THR A OG1 1 ATOM 5991 C CG2 . THR A 1 748 ? 42.579 81.794 -35.122 1.00 12.65 ? 748 THR A CG2 1 ATOM 5992 N N . LYS A 1 749 ? 40.831 80.791 -38.002 1.00 12.04 ? 749 LYS A N 1 ATOM 5993 C CA . LYS A 1 749 ? 40.985 79.646 -38.900 1.00 12.15 ? 749 LYS A CA 1 ATOM 5994 C C . LYS A 1 749 ? 42.423 79.499 -39.323 1.00 11.70 ? 749 LYS A C 1 ATOM 5995 O O . LYS A 1 749 ? 43.054 80.426 -39.882 1.00 11.81 ? 749 LYS A O 1 ATOM 5996 C CB . LYS A 1 749 ? 40.109 79.834 -40.131 1.00 14.04 ? 749 LYS A CB 1 ATOM 5997 C CG . LYS A 1 749 ? 40.296 78.712 -41.138 1.00 16.82 ? 749 LYS A CG 1 ATOM 5998 C CD . LYS A 1 749 ? 39.307 78.912 -42.317 1.00 21.24 ? 749 LYS A CD 1 ATOM 5999 C CE . LYS A 1 749 ? 39.653 77.970 -43.458 1.00 23.46 ? 749 LYS A CE 1 ATOM 6000 N NZ . LYS A 1 749 ? 39.291 78.578 -44.775 1.00 27.12 ? 749 LYS A NZ 1 ATOM 6001 N N . GLY A 1 750 ? 42.986 78.362 -38.982 1.00 11.79 ? 750 GLY A N 1 ATOM 6002 C CA . GLY A 1 750 ? 44.366 78.096 -39.311 1.00 12.22 ? 750 GLY A CA 1 ATOM 6003 C C . GLY A 1 750 ? 44.558 76.727 -39.895 1.00 12.37 ? 750 GLY A C 1 ATOM 6004 O O . GLY A 1 750 ? 43.651 75.870 -39.796 1.00 13.70 ? 750 GLY A O 1 ATOM 6005 N N . LYS A 1 751 ? 45.736 76.509 -40.450 1.00 12.42 ? 751 LYS A N 1 ATOM 6006 C CA . LYS A 1 751 ? 46.021 75.214 -41.046 1.00 13.74 ? 751 LYS A CA 1 ATOM 6007 C C . LYS A 1 751 ? 46.186 74.108 -40.012 1.00 13.43 ? 751 LYS A C 1 ATOM 6008 O O . LYS A 1 751 ? 45.841 72.942 -40.282 1.00 13.24 ? 751 LYS A O 1 ATOM 6009 C CB . LYS A 1 751 ? 47.292 75.301 -41.876 1.00 17.00 ? 751 LYS A CB 1 ATOM 6010 C CG . LYS A 1 751 ? 47.658 73.992 -42.535 1.00 23.91 ? 751 LYS A CG 1 ATOM 6011 C CD . LYS A 1 751 ? 48.740 74.161 -43.621 1.00 28.72 ? 751 LYS A CD 1 ATOM 6012 C CE . LYS A 1 751 ? 49.065 72.795 -44.206 1.00 31.20 ? 751 LYS A CE 1 ATOM 6013 N NZ . LYS A 1 751 ? 47.786 72.046 -44.493 1.00 34.25 ? 751 LYS A NZ 1 ATOM 6014 N N . LEU A 1 752 ? 46.729 74.460 -38.854 1.00 12.29 ? 752 LEU A N 1 ATOM 6015 C CA . LEU A 1 752 ? 46.948 73.468 -37.791 1.00 11.19 ? 752 LEU A CA 1 ATOM 6016 C C . LEU A 1 752 ? 45.901 73.507 -36.690 1.00 11.42 ? 752 LEU A C 1 ATOM 6017 O O . LEU A 1 752 ? 45.603 72.480 -36.064 1.00 10.91 ? 752 LEU A O 1 ATOM 6018 C CB . LEU A 1 752 ? 48.319 73.688 -37.122 1.00 12.33 ? 752 LEU A CB 1 ATOM 6019 C CG . LEU A 1 752 ? 49.560 73.668 -38.029 1.00 13.54 ? 752 LEU A CG 1 ATOM 6020 C CD1 . LEU A 1 752 ? 50.842 73.797 -37.200 1.00 15.09 ? 752 LEU A CD1 1 ATOM 6021 C CD2 . LEU A 1 752 ? 49.560 72.412 -38.882 1.00 17.17 ? 752 LEU A CD2 1 ATOM 6022 N N . GLU A 1 753 ? 45.300 74.676 -36.462 1.00 11.65 ? 753 GLU A N 1 ATOM 6023 C CA . GLU A 1 753 ? 44.366 74.805 -35.371 1.00 11.43 ? 753 GLU A CA 1 ATOM 6024 C C . GLU A 1 753 ? 43.365 75.918 -35.697 1.00 10.87 ? 753 GLU A C 1 ATOM 6025 O O . GLU A 1 753 ? 43.823 77.025 -36.124 1.00 12.37 ? 753 GLU A O 1 ATOM 6026 C CB . GLU A 1 753 ? 45.128 75.198 -34.074 1.00 11.75 ? 753 GLU A CB 1 ATOM 6027 C CG . GLU A 1 753 ? 44.207 75.387 -32.858 1.00 14.53 ? 753 GLU A CG 1 ATOM 6028 C CD . GLU A 1 753 ? 44.946 75.986 -31.644 1.00 16.59 ? 753 GLU A CD 1 ATOM 6029 O OE1 . GLU A 1 753 ? 45.251 77.203 -31.648 1.00 22.37 ? 753 GLU A OE1 1 ATOM 6030 O OE2 . GLU A 1 753 ? 45.225 75.182 -30.751 1.00 20.36 ? 753 GLU A OE2 1 ATOM 6031 N N . SER A 1 754 ? 42.086 75.638 -35.500 1.00 10.18 ? 754 SER A N 1 ATOM 6032 C CA . SER A 1 754 ? 41.016 76.614 -35.687 1.00 9.86 ? 754 SER A CA 1 ATOM 6033 C C . SER A 1 754 ? 40.140 76.632 -34.459 1.00 9.62 ? 754 SER A C 1 ATOM 6034 O O . SER A 1 754 ? 40.134 75.661 -33.646 1.00 10.20 ? 754 SER A O 1 ATOM 6035 C CB . SER A 1 754 ? 40.167 76.229 -36.885 1.00 10.83 ? 754 SER A CB 1 ATOM 6036 O OG . SER A 1 754 ? 40.925 76.369 -38.086 1.00 11.88 ? 754 SER A OG 1 ATOM 6037 N N . SER A 1 755 ? 39.364 77.689 -34.297 1.00 9.82 ? 755 SER A N 1 ATOM 6038 C CA . SER A 1 755 ? 38.497 77.766 -33.155 1.00 10.16 ? 755 SER A CA 1 ATOM 6039 C C . SER A 1 755 ? 37.329 78.686 -33.346 1.00 9.17 ? 755 SER A C 1 ATOM 6040 O O A SER A 1 755 ? 37.373 79.574 -34.200 0.50 10.24 ? 755 SER A O 1 ATOM 6041 O O B SER A 1 755 ? 37.500 79.724 -33.998 0.50 10.31 ? 755 SER A O 1 ATOM 6042 C CB A SER A 1 755 ? 39.304 78.245 -31.935 0.50 11.12 ? 755 SER A CB 1 ATOM 6043 C CB B SER A 1 755 ? 39.262 78.021 -31.810 0.50 12.51 ? 755 SER A CB 1 ATOM 6044 O OG A SER A 1 755 ? 39.955 79.468 -32.192 0.50 12.09 ? 755 SER A OG 1 ATOM 6045 O OG B SER A 1 755 ? 39.659 79.357 -31.716 0.50 13.12 ? 755 SER A OG 1 ATOM 6046 N N . VAL A 1 756 ? 36.298 78.497 -32.548 1.00 9.13 ? 756 VAL A N 1 ATOM 6047 C CA . VAL A 1 756 ? 35.149 79.362 -32.490 1.00 9.66 ? 756 VAL A CA 1 ATOM 6048 C C . VAL A 1 756 ? 35.018 79.701 -31.008 1.00 9.80 ? 756 VAL A C 1 ATOM 6049 O O . VAL A 1 756 ? 34.867 78.769 -30.151 1.00 10.15 ? 756 VAL A O 1 ATOM 6050 C CB . VAL A 1 756 ? 33.865 78.728 -32.995 1.00 10.33 ? 756 VAL A CB 1 ATOM 6051 C CG1 . VAL A 1 756 ? 32.674 79.723 -32.776 1.00 12.08 ? 756 VAL A CG1 1 ATOM 6052 C CG2 . VAL A 1 756 ? 34.051 78.343 -34.484 1.00 12.49 ? 756 VAL A CG2 1 ATOM 6053 N N . SER A 1 757 ? 35.041 80.974 -30.642 1.00 9.29 ? 757 SER A N 1 ATOM 6054 C CA . SER A 1 757 ? 34.919 81.405 -29.233 1.00 9.77 ? 757 SER A CA 1 ATOM 6055 C C . SER A 1 757 ? 33.776 82.374 -29.106 1.00 10.02 ? 757 SER A C 1 ATOM 6056 O O . SER A 1 757 ? 33.608 83.235 -30.015 1.00 11.34 ? 757 SER A O 1 ATOM 6057 C CB . SER A 1 757 ? 36.219 82.117 -28.777 1.00 10.72 ? 757 SER A CB 1 ATOM 6058 O OG . SER A 1 757 ? 37.294 81.222 -28.948 1.00 12.95 ? 757 SER A OG 1 ATOM 6059 N N . VAL A 1 758 ? 32.984 82.308 -28.061 1.00 9.83 ? 758 VAL A N 1 ATOM 6060 C CA . VAL A 1 758 ? 31.858 83.220 -27.892 1.00 10.45 ? 758 VAL A CA 1 ATOM 6061 C C . VAL A 1 758 ? 31.738 83.670 -26.470 1.00 9.95 ? 758 VAL A C 1 ATOM 6062 O O . VAL A 1 758 ? 31.914 82.876 -25.521 1.00 9.98 ? 758 VAL A O 1 ATOM 6063 C CB . VAL A 1 758 ? 30.542 82.568 -28.416 1.00 10.43 ? 758 VAL A CB 1 ATOM 6064 C CG1 . VAL A 1 758 ? 30.288 81.216 -27.700 1.00 11.06 ? 758 VAL A CG1 1 ATOM 6065 C CG2 . VAL A 1 758 ? 29.381 83.522 -28.205 1.00 11.31 ? 758 VAL A CG2 1 ATOM 6066 N N . GLY A 1 759 ? 31.483 84.951 -26.287 1.00 10.56 ? 759 GLY A N 1 ATOM 6067 C CA . GLY A 1 759 ? 31.357 85.505 -24.953 1.00 11.97 ? 759 GLY A CA 1 ATOM 6068 C C . GLY A 1 759 ? 29.914 85.491 -24.496 1.00 11.71 ? 759 GLY A C 1 ATOM 6069 O O . GLY A 1 759 ? 29.113 86.390 -24.819 1.00 12.19 ? 759 GLY A O 1 ATOM 6070 N N . LEU A 1 760 ? 29.539 84.471 -23.750 1.00 12.12 ? 760 LEU A N 1 ATOM 6071 C CA . LEU A 1 760 ? 28.171 84.338 -23.250 1.00 12.89 ? 760 LEU A CA 1 ATOM 6072 C C . LEU A 1 760 ? 28.086 84.822 -21.826 1.00 12.92 ? 760 LEU A C 1 ATOM 6073 O O . LEU A 1 760 ? 29.094 84.984 -21.143 1.00 14.03 ? 760 LEU A O 1 ATOM 6074 C CB . LEU A 1 760 ? 27.811 82.838 -23.248 1.00 13.02 ? 760 LEU A CB 1 ATOM 6075 C CG . LEU A 1 760 ? 28.001 82.136 -24.591 1.00 12.96 ? 760 LEU A CG 1 ATOM 6076 C CD1 . LEU A 1 760 ? 27.783 80.632 -24.489 1.00 14.34 ? 760 LEU A CD1 1 ATOM 6077 C CD2 . LEU A 1 760 ? 26.987 82.745 -25.619 1.00 15.89 ? 760 LEU A CD2 1 ATOM 6078 N N . PRO A 1 761 ? 26.876 85.034 -21.302 1.00 14.45 ? 761 PRO A N 1 ATOM 6079 C CA . PRO A 1 761 ? 26.832 85.485 -19.904 1.00 14.16 ? 761 PRO A CA 1 ATOM 6080 C C . PRO A 1 761 ? 27.402 84.362 -19.031 1.00 14.28 ? 761 PRO A C 1 ATOM 6081 O O . PRO A 1 761 ? 26.923 83.209 -19.099 1.00 14.58 ? 761 PRO A O 1 ATOM 6082 C CB . PRO A 1 761 ? 25.315 85.692 -19.650 1.00 15.29 ? 761 PRO A CB 1 ATOM 6083 C CG . PRO A 1 761 ? 24.823 86.035 -21.042 1.00 16.25 ? 761 PRO A CG 1 ATOM 6084 C CD . PRO A 1 761 ? 25.546 85.072 -21.938 1.00 14.97 ? 761 PRO A CD 1 ATOM 6085 N N . SER A 1 762 ? 28.410 84.751 -18.243 1.00 13.36 ? 762 SER A N 1 ATOM 6086 C CA . SER A 1 762 ? 29.120 83.899 -17.298 1.00 12.53 ? 762 SER A CA 1 ATOM 6087 C C . SER A 1 762 ? 30.050 82.880 -17.910 1.00 10.75 ? 762 SER A C 1 ATOM 6088 O O . SER A 1 762 ? 30.727 82.183 -17.163 1.00 10.94 ? 762 SER A O 1 ATOM 6089 C CB . SER A 1 762 ? 28.165 83.114 -16.419 1.00 13.19 ? 762 SER A CB 1 ATOM 6090 O OG . SER A 1 762 ? 27.258 83.922 -15.661 1.00 16.95 ? 762 SER A OG 1 ATOM 6091 N N . VAL A 1 763 ? 30.138 82.798 -19.222 1.00 10.49 ? 763 VAL A N 1 ATOM 6092 C CA . VAL A 1 763 ? 30.990 81.791 -19.846 1.00 10.88 ? 763 VAL A CA 1 ATOM 6093 C C . VAL A 1 763 ? 31.591 82.204 -21.159 1.00 10.41 ? 763 VAL A C 1 ATOM 6094 O O . VAL A 1 763 ? 30.857 82.573 -22.043 1.00 11.76 ? 763 VAL A O 1 ATOM 6095 C CB . VAL A 1 763 ? 30.218 80.464 -20.164 1.00 12.01 ? 763 VAL A CB 1 ATOM 6096 C CG1 . VAL A 1 763 ? 31.182 79.388 -20.698 1.00 11.97 ? 763 VAL A CG1 1 ATOM 6097 C CG2 . VAL A 1 763 ? 29.515 79.909 -18.921 1.00 14.96 ? 763 VAL A CG2 1 ATOM 6098 N N . VAL A 1 764 ? 32.912 82.231 -21.267 1.00 9.12 ? 764 VAL A N 1 ATOM 6099 C CA . VAL A 1 764 ? 33.507 82.402 -22.586 1.00 8.84 ? 764 VAL A CA 1 ATOM 6100 C C . VAL A 1 764 ? 33.675 80.925 -23.042 1.00 8.77 ? 764 VAL A C 1 ATOM 6101 O O . VAL A 1 764 ? 34.454 80.146 -22.463 1.00 9.29 ? 764 VAL A O 1 ATOM 6102 C CB . VAL A 1 764 ? 34.885 83.112 -22.578 1.00 9.54 ? 764 VAL A CB 1 ATOM 6103 C CG1 . VAL A 1 764 ? 35.439 83.169 -24.038 1.00 11.11 ? 764 VAL A CG1 1 ATOM 6104 C CG2 . VAL A 1 764 ? 34.727 84.543 -21.985 1.00 11.75 ? 764 VAL A CG2 1 ATOM 6105 N N . HIS A 1 765 ? 32.922 80.526 -24.069 1.00 9.39 ? 765 HIS A N 1 ATOM 6106 C CA . HIS A 1 765 ? 32.869 79.147 -24.565 1.00 8.34 ? 765 HIS A CA 1 ATOM 6107 C C . HIS A 1 765 ? 33.699 79.031 -25.805 1.00 8.87 ? 765 HIS A C 1 ATOM 6108 O O . HIS A 1 765 ? 33.517 79.843 -26.722 1.00 10.26 ? 765 HIS A O 1 ATOM 6109 C CB . HIS A 1 765 ? 31.388 78.823 -24.859 1.00 9.67 ? 765 HIS A CB 1 ATOM 6110 C CG . HIS A 1 765 ? 31.147 77.464 -25.398 1.00 8.69 ? 765 HIS A CG 1 ATOM 6111 N ND1 . HIS A 1 765 ? 30.596 77.199 -26.641 1.00 12.62 ? 765 HIS A ND1 1 ATOM 6112 C CD2 . HIS A 1 765 ? 31.347 76.262 -24.813 1.00 7.28 ? 765 HIS A CD2 1 ATOM 6113 C CE1 . HIS A 1 765 ? 30.470 75.889 -26.803 1.00 9.36 ? 765 HIS A CE1 1 ATOM 6114 N NE2 . HIS A 1 765 ? 30.925 75.295 -25.699 1.00 12.81 ? 765 HIS A NE2 1 ATOM 6115 N N . GLN A 1 766 ? 34.570 78.040 -25.888 1.00 8.66 ? 766 GLN A N 1 ATOM 6116 C CA . GLN A 1 766 ? 35.447 77.909 -27.020 1.00 8.78 ? 766 GLN A CA 1 ATOM 6117 C C . GLN A 1 766 ? 35.397 76.478 -27.505 1.00 8.34 ? 766 GLN A C 1 ATOM 6118 O O A GLN A 1 766 ? 35.329 75.537 -26.682 0.50 7.33 ? 766 GLN A O 1 ATOM 6119 O O B GLN A 1 766 ? 35.850 75.492 -26.792 0.50 8.64 ? 766 GLN A O 1 ATOM 6120 C CB . GLN A 1 766 ? 36.901 78.270 -26.596 1.00 10.53 ? 766 GLN A CB 1 ATOM 6121 C CG A GLN A 1 766 ? 37.047 79.604 -25.807 0.50 12.76 ? 766 GLN A CG 1 ATOM 6122 C CG B GLN A 1 766 ? 37.866 78.268 -27.850 0.50 10.32 ? 766 GLN A CG 1 ATOM 6123 C CD A GLN A 1 766 ? 38.083 79.564 -24.647 0.50 15.98 ? 766 GLN A CD 1 ATOM 6124 C CD B GLN A 1 766 ? 39.278 78.752 -27.527 0.50 11.61 ? 766 GLN A CD 1 ATOM 6125 O OE1 A GLN A 1 766 ? 39.259 79.277 -24.875 0.50 15.39 ? 766 GLN A OE1 1 ATOM 6126 O OE1 B GLN A 1 766 ? 40.047 79.171 -28.424 0.50 13.30 ? 766 GLN A OE1 1 ATOM 6127 N NE2 A GLN A 1 766 ? 37.635 79.863 -23.395 0.50 14.10 ? 766 GLN A NE2 1 ATOM 6128 N NE2 B GLN A 1 766 ? 39.632 78.698 -26.247 0.50 12.54 ? 766 GLN A NE2 1 ATOM 6129 N N . THR A 1 767 ? 35.385 76.311 -28.831 1.00 8.23 ? 767 THR A N 1 ATOM 6130 C CA . THR A 1 767 ? 35.490 75.019 -29.481 1.00 8.62 ? 767 THR A CA 1 ATOM 6131 C C . THR A 1 767 ? 36.755 75.072 -30.296 1.00 8.91 ? 767 THR A C 1 ATOM 6132 O O . THR A 1 767 ? 36.884 75.928 -31.201 1.00 10.21 ? 767 THR A O 1 ATOM 6133 C CB . THR A 1 767 ? 34.297 74.755 -30.367 1.00 9.50 ? 767 THR A CB 1 ATOM 6134 O OG1 . THR A 1 767 ? 33.117 74.847 -29.568 1.00 11.01 ? 767 THR A OG1 1 ATOM 6135 C CG2 . THR A 1 767 ? 34.396 73.319 -30.982 1.00 10.16 ? 767 THR A CG2 1 ATOM 6136 N N . ILE A 1 768 ? 37.715 74.196 -30.034 1.00 9.88 ? 768 ILE A N 1 ATOM 6137 C CA . ILE A 1 768 ? 39.009 74.178 -30.725 1.00 9.06 ? 768 ILE A CA 1 ATOM 6138 C C . ILE A 1 768 ? 39.171 72.914 -31.546 1.00 9.81 ? 768 ILE A C 1 ATOM 6139 O O . ILE A 1 768 ? 38.849 71.804 -31.074 1.00 11.20 ? 768 ILE A O 1 ATOM 6140 C CB . ILE A 1 768 ? 40.147 74.271 -29.717 1.00 9.77 ? 768 ILE A CB 1 ATOM 6141 C CG1 . ILE A 1 768 ? 39.939 75.523 -28.892 1.00 11.03 ? 768 ILE A CG1 1 ATOM 6142 C CG2 . ILE A 1 768 ? 41.512 74.350 -30.392 1.00 11.07 ? 768 ILE A CG2 1 ATOM 6143 C CD1 . ILE A 1 768 ? 40.769 75.487 -27.585 1.00 13.60 ? 768 ILE A CD1 1 ATOM 6144 N N . MET A 1 769 ? 39.632 73.051 -32.766 1.00 9.64 ? 769 MET A N 1 ATOM 6145 C CA . MET A 1 769 ? 39.797 71.919 -33.689 1.00 9.57 ? 769 MET A CA 1 ATOM 6146 C C . MET A 1 769 ? 41.228 71.809 -34.129 1.00 10.76 ? 769 MET A C 1 ATOM 6147 O O . MET A 1 769 ? 41.849 72.792 -34.595 1.00 10.92 ? 769 MET A O 1 ATOM 6148 C CB . MET A 1 769 ? 38.938 72.181 -34.926 1.00 11.83 ? 769 MET A CB 1 ATOM 6149 C CG . MET A 1 769 ? 37.490 72.314 -34.547 1.00 12.19 ? 769 MET A CG 1 ATOM 6150 S SD . MET A 1 769 ? 36.454 72.922 -35.879 1.00 15.84 ? 769 MET A SD 1 ATOM 6151 C CE . MET A 1 769 ? 36.774 71.556 -37.026 1.00 18.30 ? 769 MET A CE 1 ATOM 6152 N N . ARG A 1 770 ? 41.809 70.632 -33.941 1.00 11.27 ? 770 ARG A N 1 ATOM 6153 C CA . ARG A 1 770 ? 43.167 70.419 -34.356 1.00 13.06 ? 770 ARG A CA 1 ATOM 6154 C C . ARG A 1 770 ? 43.270 69.233 -35.317 1.00 15.03 ? 770 ARG A C 1 ATOM 6155 O O . ARG A 1 770 ? 44.371 68.730 -35.538 1.00 16.34 ? 770 ARG A O 1 ATOM 6156 C CB . ARG A 1 770 ? 44.067 70.231 -33.126 1.00 13.52 ? 770 ARG A CB 1 ATOM 6157 C CG A ARG A 1 770 ? 43.851 71.298 -32.037 0.50 14.11 ? 770 ARG A CG 1 ATOM 6158 C CG B ARG A 1 770 ? 44.360 71.274 -32.386 0.50 13.15 ? 770 ARG A CG 1 ATOM 6159 C CD A ARG A 1 770 ? 45.001 71.355 -31.001 0.50 14.48 ? 770 ARG A CD 1 ATOM 6160 C CD B ARG A 1 770 ? 45.211 70.802 -31.230 0.50 14.37 ? 770 ARG A CD 1 ATOM 6161 N NE A ARG A 1 770 ? 44.813 72.355 -29.949 0.50 16.43 ? 770 ARG A NE 1 ATOM 6162 N NE B ARG A 1 770 ? 44.537 69.697 -30.559 0.50 16.06 ? 770 ARG A NE 1 ATOM 6163 C CZ A ARG A 1 770 ? 44.031 72.187 -28.886 0.50 15.62 ? 770 ARG A CZ 1 ATOM 6164 C CZ B ARG A 1 770 ? 43.764 69.839 -29.490 0.50 16.80 ? 770 ARG A CZ 1 ATOM 6165 N NH1 A ARG A 1 770 ? 43.353 71.059 -28.741 0.50 17.22 ? 770 ARG A NH1 1 ATOM 6166 N NH1 B ARG A 1 770 ? 43.563 71.039 -28.953 0.50 18.11 ? 770 ARG A NH1 1 ATOM 6167 N NH2 A ARG A 1 770 ? 43.956 73.122 -27.946 0.50 15.81 ? 770 ARG A NH2 1 ATOM 6168 N NH2 B ARG A 1 770 ? 43.196 68.774 -28.952 0.50 15.96 ? 770 ARG A NH2 1 ATOM 6169 N N . GLY A 1 771 ? 42.128 68.792 -35.852 1.00 15.39 ? 771 GLY A N 1 ATOM 6170 C CA . GLY A 1 771 ? 42.139 67.705 -36.809 1.00 17.55 ? 771 GLY A CA 1 ATOM 6171 C C . GLY A 1 771 ? 41.449 66.431 -36.429 1.00 19.01 ? 771 GLY A C 1 ATOM 6172 O O . GLY A 1 771 ? 41.193 65.573 -37.303 1.00 20.05 ? 771 GLY A O 1 ATOM 6173 N N . GLY A 1 772 ? 41.180 66.279 -35.134 1.00 18.05 ? 772 GLY A N 1 ATOM 6174 C CA . GLY A 1 772 ? 40.480 65.102 -34.596 1.00 16.71 ? 772 GLY A CA 1 ATOM 6175 C C . GLY A 1 772 ? 39.325 65.565 -33.698 1.00 15.96 ? 772 GLY A C 1 ATOM 6176 O O . GLY A 1 772 ? 38.651 66.550 -34.018 1.00 14.77 ? 772 GLY A O 1 ATOM 6177 N N . ALA A 1 773 ? 39.078 64.892 -32.570 1.00 13.80 ? 773 ALA A N 1 ATOM 6178 C CA . ALA A 1 773 ? 37.971 65.285 -31.702 1.00 12.95 ? 773 ALA A CA 1 ATOM 6179 C C . ALA A 1 773 ? 38.197 66.710 -31.216 1.00 10.53 ? 773 ALA A C 1 ATOM 6180 O O . ALA A 1 773 ? 39.302 67.052 -30.803 1.00 10.83 ? 773 ALA A O 1 ATOM 6181 C CB . ALA A 1 773 ? 37.886 64.372 -30.508 1.00 14.68 ? 773 ALA A CB 1 ATOM 6182 N N . PRO A 1 774 ? 37.158 67.520 -31.218 1.00 10.08 ? 774 PRO A N 1 ATOM 6183 C CA . PRO A 1 774 ? 37.369 68.895 -30.751 1.00 10.35 ? 774 PRO A CA 1 ATOM 6184 C C . PRO A 1 774 ? 37.650 68.946 -29.265 1.00 9.83 ? 774 PRO A C 1 ATOM 6185 O O . PRO A 1 774 ? 37.362 68.010 -28.518 1.00 9.31 ? 774 PRO A O 1 ATOM 6186 C CB . PRO A 1 774 ? 36.046 69.624 -31.074 1.00 12.11 ? 774 PRO A CB 1 ATOM 6187 C CG . PRO A 1 774 ? 35.077 68.569 -31.235 1.00 14.90 ? 774 PRO A CG 1 ATOM 6188 C CD . PRO A 1 774 ? 35.825 67.364 -31.813 1.00 11.29 ? 774 PRO A CD 1 ATOM 6189 N N . GLU A 1 775 ? 38.212 70.058 -28.869 1.00 9.33 ? 775 GLU A N 1 ATOM 6190 C CA . GLU A 1 775 ? 38.457 70.395 -27.478 1.00 8.62 ? 775 GLU A CA 1 ATOM 6191 C C . GLU A 1 775 ? 37.533 71.533 -27.124 1.00 7.79 ? 775 GLU A C 1 ATOM 6192 O O . GLU A 1 775 ? 37.381 72.484 -27.940 1.00 10.63 ? 775 GLU A O 1 ATOM 6193 C CB . GLU A 1 775 ? 39.896 70.839 -27.269 1.00 9.27 ? 775 GLU A CB 1 ATOM 6194 C CG . GLU A 1 775 ? 40.216 71.260 -25.796 1.00 10.61 ? 775 GLU A CG 1 ATOM 6195 C CD . GLU A 1 775 ? 41.677 71.493 -25.565 1.00 15.82 ? 775 GLU A CD 1 ATOM 6196 O OE1 . GLU A 1 775 ? 42.499 70.710 -26.064 1.00 19.27 ? 775 GLU A OE1 1 ATOM 6197 O OE2 . GLU A 1 775 ? 42.004 72.433 -24.852 1.00 18.77 ? 775 GLU A OE2 1 ATOM 6198 N N . ILE A 1 776 ? 36.870 71.486 -25.993 1.00 7.79 ? 776 ILE A N 1 ATOM 6199 C CA . ILE A 1 776 ? 36.024 72.565 -25.548 1.00 8.34 ? 776 ILE A CA 1 ATOM 6200 C C . ILE A 1 776 ? 36.667 73.178 -24.319 1.00 7.61 ? 776 ILE A C 1 ATOM 6201 O O . ILE A 1 776 ? 37.118 72.445 -23.425 1.00 8.13 ? 776 ILE A O 1 ATOM 6202 C CB . ILE A 1 776 ? 34.625 72.051 -25.139 1.00 9.10 ? 776 ILE A CB 1 ATOM 6203 C CG1 . ILE A 1 776 ? 34.072 71.103 -26.218 1.00 12.76 ? 776 ILE A CG1 1 ATOM 6204 C CG2 . ILE A 1 776 ? 33.738 73.239 -24.701 1.00 10.01 ? 776 ILE A CG2 1 ATOM 6205 C CD1 . ILE A 1 776 ? 33.922 71.667 -27.628 1.00 14.76 ? 776 ILE A CD1 1 ATOM 6206 N N . ARG A 1 777 ? 36.718 74.498 -24.258 1.00 8.27 ? 777 ARG A N 1 ATOM 6207 C CA . ARG A 1 777 ? 37.196 75.210 -23.054 1.00 7.84 ? 777 ARG A CA 1 ATOM 6208 C C . ARG A 1 777 ? 36.138 76.202 -22.650 1.00 8.99 ? 777 ARG A C 1 ATOM 6209 O O . ARG A 1 777 ? 35.615 77.007 -23.489 1.00 10.11 ? 777 ARG A O 1 ATOM 6210 C CB . ARG A 1 777 ? 38.499 75.984 -23.321 1.00 9.94 ? 777 ARG A CB 1 ATOM 6211 C CG . ARG A 1 777 ? 39.658 75.088 -23.692 1.00 9.51 ? 777 ARG A CG 1 ATOM 6212 C CD . ARG A 1 777 ? 40.945 75.901 -23.812 1.00 11.21 ? 777 ARG A CD 1 ATOM 6213 N NE . ARG A 1 777 ? 42.024 75.042 -24.259 1.00 12.63 ? 777 ARG A NE 1 ATOM 6214 C CZ . ARG A 1 777 ? 43.227 75.501 -24.588 1.00 17.05 ? 777 ARG A CZ 1 ATOM 6215 N NH1 . ARG A 1 777 ? 43.474 76.808 -24.476 1.00 18.99 ? 777 ARG A NH1 1 ATOM 6216 N NH2 . ARG A 1 777 ? 44.150 74.675 -25.105 1.00 19.05 ? 777 ARG A NH2 1 ATOM 6217 N N . ASN A 1 778 ? 35.789 76.213 -21.395 1.00 7.97 ? 778 ASN A N 1 ATOM 6218 C CA . ASN A 1 778 ? 34.852 77.176 -20.837 1.00 8.00 ? 778 ASN A CA 1 ATOM 6219 C C . ASN A 1 778 ? 35.551 77.994 -19.760 1.00 8.03 ? 778 ASN A C 1 ATOM 6220 O O . ASN A 1 778 ? 36.001 77.415 -18.725 1.00 7.69 ? 778 ASN A O 1 ATOM 6221 C CB . ASN A 1 778 ? 33.627 76.516 -20.163 1.00 8.64 ? 778 ASN A CB 1 ATOM 6222 C CG . ASN A 1 778 ? 32.679 75.836 -21.144 1.00 8.58 ? 778 ASN A CG 1 ATOM 6223 O OD1 . ASN A 1 778 ? 32.615 76.171 -22.327 1.00 9.67 ? 778 ASN A OD1 1 ATOM 6224 N ND2 . ASN A 1 778 ? 31.904 74.877 -20.635 1.00 9.52 ? 778 ASN A ND2 1 ATOM 6225 N N . LEU A 1 779 ? 35.618 79.317 -19.942 1.00 8.07 ? 779 LEU A N 1 ATOM 6226 C CA . LEU A 1 779 ? 36.138 80.187 -18.870 1.00 8.37 ? 779 LEU A CA 1 ATOM 6227 C C . LEU A 1 779 ? 34.863 80.596 -18.145 1.00 8.54 ? 779 LEU A C 1 ATOM 6228 O O . LEU A 1 779 ? 34.044 81.380 -18.658 1.00 9.51 ? 779 LEU A O 1 ATOM 6229 C CB . LEU A 1 779 ? 36.902 81.381 -19.487 1.00 10.72 ? 779 LEU A CB 1 ATOM 6230 C CG . LEU A 1 779 ? 37.458 82.334 -18.413 1.00 13.40 ? 779 LEU A CG 1 ATOM 6231 C CD1 . LEU A 1 779 ? 38.453 81.671 -17.530 1.00 15.11 ? 779 LEU A CD1 1 ATOM 6232 C CD2 . LEU A 1 779 ? 38.057 83.540 -19.182 1.00 17.34 ? 779 LEU A CD2 1 ATOM 6233 N N . VAL A 1 780 ? 34.651 80.001 -16.982 1.00 8.21 ? 780 VAL A N 1 ATOM 6234 C CA . VAL A 1 780 ? 33.400 80.170 -16.244 1.00 9.30 ? 780 VAL A CA 1 ATOM 6235 C C . VAL A 1 780 ? 33.545 81.171 -15.091 1.00 9.73 ? 780 VAL A C 1 ATOM 6236 O O . VAL A 1 780 ? 34.344 80.971 -14.180 1.00 9.80 ? 780 VAL A O 1 ATOM 6237 C CB . VAL A 1 780 ? 32.917 78.800 -15.687 1.00 8.77 ? 780 VAL A CB 1 ATOM 6238 C CG1 . VAL A 1 780 ? 31.609 78.976 -14.926 1.00 10.14 ? 780 VAL A CG1 1 ATOM 6239 C CG2 . VAL A 1 780 ? 32.818 77.772 -16.804 1.00 9.81 ? 780 VAL A CG2 1 ATOM 6240 N N . ASP A 1 781 ? 32.785 82.271 -15.157 1.00 9.86 ? 781 ASP A N 1 ATOM 6241 C CA . ASP A 1 781 ? 32.761 83.304 -14.103 1.00 10.20 ? 781 ASP A CA 1 ATOM 6242 C C . ASP A 1 781 ? 31.339 83.615 -13.757 1.00 10.83 ? 781 ASP A C 1 ATOM 6243 O O . ASP A 1 781 ? 30.678 84.444 -14.410 1.00 11.27 ? 781 ASP A O 1 ATOM 6244 C CB . ASP A 1 781 ? 33.452 84.551 -14.602 1.00 11.87 ? 781 ASP A CB 1 ATOM 6245 C CG . ASP A 1 781 ? 33.531 85.597 -13.528 1.00 12.96 ? 781 ASP A CG 1 ATOM 6246 O OD1 . ASP A 1 781 ? 33.086 85.341 -12.396 1.00 12.24 ? 781 ASP A OD1 1 ATOM 6247 O OD2 . ASP A 1 781 ? 34.080 86.680 -13.860 1.00 17.35 ? 781 ASP A OD2 1 ATOM 6248 N N . ILE A 1 782 ? 30.830 82.906 -12.765 1.00 10.84 ? 782 ILE A N 1 ATOM 6249 C CA . ILE A 1 782 ? 29.423 83.034 -12.338 1.00 12.28 ? 782 ILE A CA 1 ATOM 6250 C C . ILE A 1 782 ? 29.172 84.392 -11.718 1.00 14.36 ? 782 ILE A C 1 ATOM 6251 O O . ILE A 1 782 ? 28.013 84.750 -11.418 1.00 16.07 ? 782 ILE A O 1 ATOM 6252 C CB . ILE A 1 782 ? 29.073 81.810 -11.435 1.00 13.46 ? 782 ILE A CB 1 ATOM 6253 C CG1 . ILE A 1 782 ? 27.576 81.654 -11.217 1.00 14.07 ? 782 ILE A CG1 1 ATOM 6254 C CG2 . ILE A 1 782 ? 29.749 81.962 -10.091 1.00 13.82 ? 782 ILE A CG2 1 ATOM 6255 C CD1 . ILE A 1 782 ? 27.261 80.266 -10.724 1.00 15.11 ? 782 ILE A CD1 1 ATOM 6256 N N . GLY A 1 783 ? 30.244 85.159 -11.498 1.00 14.27 ? 783 GLY A N 1 ATOM 6257 C CA . GLY A 1 783 ? 30.065 86.536 -11.041 1.00 15.41 ? 783 GLY A CA 1 ATOM 6258 C C . GLY A 1 783 ? 29.239 86.637 -9.777 1.00 15.75 ? 783 GLY A C 1 ATOM 6259 O O . GLY A 1 783 ? 29.491 85.901 -8.816 1.00 17.53 ? 783 GLY A O 1 ATOM 6260 N N . SER A 1 784 ? 28.243 87.526 -9.766 1.00 18.43 ? 784 SER A N 1 ATOM 6261 C CA . SER A 1 784 ? 27.448 87.645 -8.545 1.00 19.45 ? 784 SER A CA 1 ATOM 6262 C C . SER A 1 784 ? 26.043 87.054 -8.674 1.00 19.55 ? 784 SER A C 1 ATOM 6263 O O . SER A 1 784 ? 25.108 87.460 -7.949 1.00 19.99 ? 784 SER A O 1 ATOM 6264 C CB . SER A 1 784 ? 27.357 89.105 -8.107 1.00 21.12 ? 784 SER A CB 1 ATOM 6265 O OG . SER A 1 784 ? 26.760 89.889 -9.131 1.00 24.74 ? 784 SER A OG 1 ATOM 6266 N N . LEU A 1 785 ? 25.889 86.087 -9.576 1.00 18.63 ? 785 LEU A N 1 ATOM 6267 C CA . LEU A 1 785 ? 24.588 85.451 -9.766 1.00 18.75 ? 785 LEU A CA 1 ATOM 6268 C C . LEU A 1 785 ? 24.258 84.547 -8.602 1.00 19.74 ? 785 LEU A C 1 ATOM 6269 O O . LEU A 1 785 ? 24.590 83.342 -8.613 1.00 21.58 ? 785 LEU A O 1 ATOM 6270 C CB . LEU A 1 785 ? 24.571 84.611 -11.038 1.00 18.89 ? 785 LEU A CB 1 ATOM 6271 C CG . LEU A 1 785 ? 24.806 85.366 -12.342 1.00 19.06 ? 785 LEU A CG 1 ATOM 6272 C CD1 . LEU A 1 785 ? 24.791 84.409 -13.487 1.00 22.00 ? 785 LEU A CD1 1 ATOM 6273 C CD2 . LEU A 1 785 ? 23.772 86.475 -12.473 1.00 19.82 ? 785 LEU A CD2 1 ATOM 6274 N N . ASP A 1 786 ? 23.511 85.030 -7.631 1.00 19.14 ? 786 ASP A N 1 ATOM 6275 C CA . ASP A 1 786 ? 23.269 84.158 -6.500 1.00 18.76 ? 786 ASP A CA 1 ATOM 6276 C C . ASP A 1 786 ? 22.215 83.104 -6.797 1.00 15.51 ? 786 ASP A C 1 ATOM 6277 O O . ASP A 1 786 ? 21.394 83.242 -7.700 1.00 15.64 ? 786 ASP A O 1 ATOM 6278 C CB . ASP A 1 786 ? 22.879 84.920 -5.224 1.00 21.35 ? 786 ASP A CB 1 ATOM 6279 C CG . ASP A 1 786 ? 23.886 85.997 -4.857 1.00 24.35 ? 786 ASP A CG 1 ATOM 6280 O OD1 . ASP A 1 786 ? 25.143 85.775 -4.811 1.00 22.49 ? 786 ASP A OD1 1 ATOM 6281 O OD2 . ASP A 1 786 ? 23.397 87.113 -4.627 1.00 26.96 ? 786 ASP A OD2 1 ATOM 6282 N N . ASN A 1 787 ? 22.345 82.024 -6.039 1.00 14.31 ? 787 ASN A N 1 ATOM 6283 C CA . ASN A 1 787 ? 21.442 80.892 -6.121 1.00 13.05 ? 787 ASN A CA 1 ATOM 6284 C C . ASN A 1 787 ? 21.255 80.421 -7.526 1.00 12.47 ? 787 ASN A C 1 ATOM 6285 O O . ASN A 1 787 ? 20.141 80.209 -8.012 1.00 13.76 ? 787 ASN A O 1 ATOM 6286 C CB . ASN A 1 787 ? 20.131 81.253 -5.403 1.00 14.47 ? 787 ASN A CB 1 ATOM 6287 C CG . ASN A 1 787 ? 20.382 81.529 -3.969 1.00 17.96 ? 787 ASN A CG 1 ATOM 6288 O OD1 . ASN A 1 787 ? 21.052 80.716 -3.302 1.00 18.16 ? 787 ASN A OD1 1 ATOM 6289 N ND2 . ASN A 1 787 ? 19.900 82.704 -3.462 1.00 22.34 ? 787 ASN A ND2 1 ATOM 6290 N N . THR A 1 788 ? 22.387 80.211 -8.199 1.00 11.28 ? 788 THR A N 1 ATOM 6291 C CA . THR A 1 788 ? 22.384 79.800 -9.589 1.00 11.06 ? 788 THR A CA 1 ATOM 6292 C C . THR A 1 788 ? 23.424 78.688 -9.819 1.00 10.10 ? 788 THR A C 1 ATOM 6293 O O . THR A 1 788 ? 24.522 78.756 -9.256 1.00 10.84 ? 788 THR A O 1 ATOM 6294 C CB . THR A 1 788 ? 22.805 80.995 -10.464 1.00 12.50 ? 788 THR A CB 1 ATOM 6295 O OG1 . THR A 1 788 ? 21.803 82.034 -10.324 1.00 14.19 ? 788 THR A OG1 1 ATOM 6296 C CG2 . THR A 1 788 ? 22.862 80.615 -11.917 1.00 14.04 ? 788 THR A CG2 1 ATOM 6297 N N . GLU A 1 789 ? 23.036 77.676 -10.597 1.00 9.15 ? 789 GLU A N 1 ATOM 6298 C CA . GLU A 1 789 ? 23.993 76.631 -11.003 1.00 9.47 ? 789 GLU A CA 1 ATOM 6299 C C . GLU A 1 789 ? 23.977 76.660 -12.521 1.00 9.68 ? 789 GLU A C 1 ATOM 6300 O O . GLU A 1 789 ? 22.900 76.572 -13.131 1.00 11.16 ? 789 GLU A O 1 ATOM 6301 C CB . GLU A 1 789 ? 23.619 75.226 -10.420 1.00 9.85 ? 789 GLU A CB 1 ATOM 6302 C CG . GLU A 1 789 ? 23.233 75.279 -8.957 1.00 10.50 ? 789 GLU A CG 1 ATOM 6303 C CD . GLU A 1 789 ? 23.457 73.956 -8.209 1.00 9.26 ? 789 GLU A CD 1 ATOM 6304 O OE1 . GLU A 1 789 ? 24.290 73.139 -8.708 1.00 9.66 ? 789 GLU A OE1 1 ATOM 6305 O OE2 . GLU A 1 789 ? 22.809 73.810 -7.153 1.00 9.76 ? 789 GLU A OE2 1 ATOM 6306 N N . ILE A 1 790 ? 25.123 76.823 -13.172 1.00 8.85 ? 790 ILE A N 1 ATOM 6307 C CA . ILE A 1 790 ? 25.208 76.866 -14.612 1.00 9.93 ? 790 ILE A CA 1 ATOM 6308 C C . ILE A 1 790 ? 25.569 75.495 -15.145 1.00 9.08 ? 790 ILE A C 1 ATOM 6309 O O . ILE A 1 790 ? 26.572 74.888 -14.677 1.00 9.63 ? 790 ILE A O 1 ATOM 6310 C CB . ILE A 1 790 ? 26.311 77.854 -15.082 1.00 10.82 ? 790 ILE A CB 1 ATOM 6311 C CG1 . ILE A 1 790 ? 25.961 79.287 -14.604 1.00 14.61 ? 790 ILE A CG1 1 ATOM 6312 C CG2 . ILE A 1 790 ? 26.440 77.782 -16.634 1.00 11.82 ? 790 ILE A CG2 1 ATOM 6313 C CD1 . ILE A 1 790 ? 27.203 80.247 -14.691 1.00 17.97 ? 790 ILE A CD1 1 ATOM 6314 N N . VAL A 1 791 ? 24.767 74.995 -16.070 1.00 8.86 ? 791 VAL A N 1 ATOM 6315 C CA . VAL A 1 791 ? 24.995 73.681 -16.661 1.00 8.48 ? 791 VAL A CA 1 ATOM 6316 C C . VAL A 1 791 ? 25.245 73.777 -18.152 1.00 8.72 ? 791 VAL A C 1 ATOM 6317 O O . VAL A 1 791 ? 24.659 74.688 -18.854 1.00 9.14 ? 791 VAL A O 1 ATOM 6318 C CB . VAL A 1 791 ? 23.776 72.740 -16.351 1.00 8.33 ? 791 VAL A CB 1 ATOM 6319 C CG1 . VAL A 1 791 ? 22.465 73.208 -17.115 1.00 10.60 ? 791 VAL A CG1 1 ATOM 6320 C CG2 . VAL A 1 791 ? 24.104 71.304 -16.753 1.00 9.67 ? 791 VAL A CG2 1 ATOM 6321 N N . MET A 1 792 ? 26.128 72.937 -18.653 1.00 8.13 ? 792 MET A N 1 ATOM 6322 C CA . MET A 1 792 ? 26.396 72.830 -20.078 1.00 8.31 ? 792 MET A CA 1 ATOM 6323 C C . MET A 1 792 ? 25.731 71.515 -20.537 1.00 7.83 ? 792 MET A C 1 ATOM 6324 O O . MET A 1 792 ? 26.048 70.426 -20.023 1.00 9.54 ? 792 MET A O 1 ATOM 6325 C CB . MET A 1 792 ? 27.921 72.794 -20.382 1.00 9.05 ? 792 MET A CB 1 ATOM 6326 C CG . MET A 1 792 ? 28.192 72.601 -21.893 1.00 10.02 ? 792 MET A CG 1 ATOM 6327 S SD . MET A 1 792 ? 29.948 72.719 -22.254 1.00 10.01 ? 792 MET A SD 1 ATOM 6328 C CE . MET A 1 792 ? 30.544 71.200 -21.464 1.00 11.64 ? 792 MET A CE 1 ATOM 6329 N N . ARG A 1 793 ? 24.798 71.609 -21.479 1.00 9.16 ? 793 ARG A N 1 ATOM 6330 C CA . ARG A 1 793 ? 24.090 70.439 -22.002 1.00 9.28 ? 793 ARG A CA 1 ATOM 6331 C C . ARG A 1 793 ? 24.388 70.234 -23.469 1.00 9.33 ? 793 ARG A C 1 ATOM 6332 O O . ARG A 1 793 ? 24.619 71.200 -24.230 1.00 10.20 ? 793 ARG A O 1 ATOM 6333 C CB . ARG A 1 793 ? 22.581 70.678 -21.797 1.00 9.84 ? 793 ARG A CB 1 ATOM 6334 C CG . ARG A 1 793 ? 21.750 69.441 -22.236 1.00 9.81 ? 793 ARG A CG 1 ATOM 6335 C CD . ARG A 1 793 ? 20.250 69.690 -21.965 1.00 10.19 ? 793 ARG A CD 1 ATOM 6336 N NE . ARG A 1 793 ? 19.985 69.723 -20.536 1.00 10.78 ? 793 ARG A NE 1 ATOM 6337 C CZ . ARG A 1 793 ? 18.929 70.297 -19.974 1.00 10.66 ? 793 ARG A CZ 1 ATOM 6338 N NH1 . ARG A 1 793 ? 17.995 70.912 -20.758 1.00 11.97 ? 793 ARG A NH1 1 ATOM 6339 N NH2 . ARG A 1 793 ? 18.836 70.354 -18.653 1.00 12.14 ? 793 ARG A NH2 1 ATOM 6340 N N . LEU A 1 794 ? 24.427 68.977 -23.877 1.00 9.36 ? 794 LEU A N 1 ATOM 6341 C CA . LEU A 1 794 ? 24.580 68.531 -25.245 1.00 9.78 ? 794 LEU A CA 1 ATOM 6342 C C . LEU A 1 794 ? 23.242 67.845 -25.608 1.00 10.37 ? 794 LEU A C 1 ATOM 6343 O O . LEU A 1 794 ? 22.758 66.980 -24.883 1.00 10.74 ? 794 LEU A O 1 ATOM 6344 C CB . LEU A 1 794 ? 25.720 67.534 -25.373 1.00 12.09 ? 794 LEU A CB 1 ATOM 6345 C CG . LEU A 1 794 ? 27.075 68.202 -25.478 1.00 10.84 ? 794 LEU A CG 1 ATOM 6346 C CD1 . LEU A 1 794 ? 28.171 67.191 -25.102 1.00 12.75 ? 794 LEU A CD1 1 ATOM 6347 C CD2 . LEU A 1 794 ? 27.270 68.631 -26.948 1.00 14.44 ? 794 LEU A CD2 1 ATOM 6348 N N . GLU A 1 795 ? 22.644 68.271 -26.723 1.00 10.48 ? 795 GLU A N 1 ATOM 6349 C CA . GLU A 1 795 ? 21.392 67.663 -27.217 1.00 11.91 ? 795 GLU A CA 1 ATOM 6350 C C . GLU A 1 795 ? 21.686 66.961 -28.520 1.00 11.78 ? 795 GLU A C 1 ATOM 6351 O O . GLU A 1 795 ? 22.210 67.542 -29.451 1.00 13.25 ? 795 GLU A O 1 ATOM 6352 C CB . GLU A 1 795 ? 20.312 68.736 -27.447 1.00 13.32 ? 795 GLU A CB 1 ATOM 6353 C CG . GLU A 1 795 ? 19.921 69.452 -26.170 1.00 17.20 ? 795 GLU A CG 1 ATOM 6354 C CD . GLU A 1 795 ? 19.015 70.693 -26.387 1.00 17.79 ? 795 GLU A CD 1 ATOM 6355 O OE1 . GLU A 1 795 ? 19.009 71.236 -27.517 1.00 21.90 ? 795 GLU A OE1 1 ATOM 6356 O OE2 . GLU A 1 795 ? 18.343 71.144 -25.430 1.00 18.80 ? 795 GLU A OE2 1 ATOM 6357 N N . THR A 1 796 ? 21.310 65.687 -28.616 1.00 11.77 ? 796 THR A N 1 ATOM 6358 C CA . THR A 1 796 ? 21.528 64.920 -29.783 1.00 11.83 ? 796 THR A CA 1 ATOM 6359 C C . THR A 1 796 ? 20.282 64.078 -30.087 1.00 12.44 ? 796 THR A C 1 ATOM 6360 O O . THR A 1 796 ? 19.305 64.105 -29.305 1.00 14.61 ? 796 THR A O 1 ATOM 6361 C CB . THR A 1 796 ? 22.690 63.896 -29.662 1.00 12.03 ? 796 THR A CB 1 ATOM 6362 O OG1 . THR A 1 796 ? 22.273 62.749 -28.878 1.00 11.11 ? 796 THR A OG1 1 ATOM 6363 C CG2 . THR A 1 796 ? 23.925 64.541 -28.938 1.00 12.38 ? 796 THR A CG2 1 ATOM 6364 N N . HIS A 1 797 ? 20.348 63.345 -31.189 1.00 13.40 ? 797 HIS A N 1 ATOM 6365 C CA . HIS A 1 797 ? 19.230 62.458 -31.523 1.00 14.09 ? 797 HIS A CA 1 ATOM 6366 C C A HIS A 1 797 ? 19.690 60.971 -31.390 0.50 14.75 ? 797 HIS A C 1 ATOM 6367 C C B HIS A 1 797 ? 19.537 61.024 -31.167 0.50 14.31 ? 797 HIS A C 1 ATOM 6368 O O A HIS A 1 797 ? 19.198 60.041 -32.039 0.50 14.78 ? 797 HIS A O 1 ATOM 6369 O O B HIS A 1 797 ? 18.615 60.227 -31.365 0.50 11.81 ? 797 HIS A O 1 ATOM 6370 C CB A HIS A 1 797 ? 18.637 62.856 -32.897 0.50 13.48 ? 797 HIS A CB 1 ATOM 6371 C CB B HIS A 1 797 ? 19.331 62.376 -33.132 0.50 14.17 ? 797 HIS A CB 1 ATOM 6372 C CG A HIS A 1 797 ? 18.046 64.242 -32.924 0.50 12.69 ? 797 HIS A CG 1 ATOM 6373 C CG B HIS A 1 797 ? 18.551 63.499 -33.697 0.50 12.96 ? 797 HIS A CG 1 ATOM 6374 N ND1 A HIS A 1 797 ? 17.720 64.907 -34.093 0.50 12.68 ? 797 HIS A ND1 1 ATOM 6375 N ND1 B HIS A 1 797 ? 18.680 63.924 -34.996 0.50 14.17 ? 797 HIS A ND1 1 ATOM 6376 C CD2 A HIS A 1 797 ? 17.753 65.097 -31.916 0.50 12.77 ? 797 HIS A CD2 1 ATOM 6377 C CD2 B HIS A 1 797 ? 17.704 64.360 -33.094 0.50 14.51 ? 797 HIS A CD2 1 ATOM 6378 C CE1 A HIS A 1 797 ? 17.253 66.107 -33.798 0.50 12.26 ? 797 HIS A CE1 1 ATOM 6379 C CE1 B HIS A 1 797 ? 17.946 65.006 -35.168 0.50 13.86 ? 797 HIS A CE1 1 ATOM 6380 N NE2 A HIS A 1 797 ? 17.263 66.250 -32.486 0.50 14.74 ? 797 HIS A NE2 1 ATOM 6381 N NE2 B HIS A 1 797 ? 17.346 65.294 -34.030 0.50 13.98 ? 797 HIS A NE2 1 ATOM 6382 N N . ILE A 1 798 ? 20.686 60.751 -30.531 1.00 13.93 ? 798 ILE A N 1 ATOM 6383 C CA . ILE A 1 798 ? 21.105 59.398 -30.156 1.00 12.79 ? 798 ILE A CA 1 ATOM 6384 C C . ILE A 1 798 ? 19.990 58.827 -29.270 1.00 11.72 ? 798 ILE A C 1 ATOM 6385 O O . ILE A 1 798 ? 19.469 59.469 -28.363 1.00 12.76 ? 798 ILE A O 1 ATOM 6386 C CB . ILE A 1 798 ? 22.445 59.434 -29.407 1.00 11.76 ? 798 ILE A CB 1 ATOM 6387 C CG1 . ILE A 1 798 ? 23.558 59.915 -30.323 1.00 13.02 ? 798 ILE A CG1 1 ATOM 6388 C CG2 . ILE A 1 798 ? 22.772 58.042 -28.861 1.00 14.05 ? 798 ILE A CG2 1 ATOM 6389 C CD1 . ILE A 1 798 ? 24.942 60.207 -29.609 1.00 13.66 ? 798 ILE A CD1 1 ATOM 6390 N N . ASP A 1 799 ? 19.572 57.586 -29.630 1.00 13.49 ? 799 ASP A N 1 ATOM 6391 C CA . ASP A 1 799 ? 18.476 56.927 -28.975 1.00 12.35 ? 799 ASP A CA 1 ATOM 6392 C C . ASP A 1 799 ? 18.988 56.140 -27.789 1.00 12.07 ? 799 ASP A C 1 ATOM 6393 O O . ASP A 1 799 ? 18.946 54.934 -27.730 1.00 11.34 ? 799 ASP A O 1 ATOM 6394 C CB . ASP A 1 799 ? 17.731 55.976 -29.961 1.00 15.79 ? 799 ASP A CB 1 ATOM 6395 C CG . ASP A 1 799 ? 16.388 55.495 -29.399 1.00 16.52 ? 799 ASP A CG 1 ATOM 6396 O OD1 . ASP A 1 799 ? 15.908 55.952 -28.334 1.00 21.64 ? 799 ASP A OD1 1 ATOM 6397 O OD2 . ASP A 1 799 ? 15.839 54.563 -30.000 1.00 23.25 ? 799 ASP A OD2 1 ATOM 6398 N N . SER A 1 800 ? 19.410 56.914 -26.798 1.00 11.17 ? 800 SER A N 1 ATOM 6399 C CA . SER A 1 800 ? 19.978 56.327 -25.597 1.00 10.72 ? 800 SER A CA 1 ATOM 6400 C C . SER A 1 800 ? 18.928 55.945 -24.574 1.00 10.54 ? 800 SER A C 1 ATOM 6401 O O . SER A 1 800 ? 19.213 55.166 -23.663 1.00 11.29 ? 800 SER A O 1 ATOM 6402 C CB . SER A 1 800 ? 21.005 57.331 -24.980 1.00 11.01 ? 800 SER A CB 1 ATOM 6403 O OG . SER A 1 800 ? 20.356 58.530 -24.628 1.00 11.17 ? 800 SER A OG 1 ATOM 6404 N N . GLY A 1 801 ? 17.697 56.448 -24.689 1.00 10.85 ? 801 GLY A N 1 ATOM 6405 C CA . GLY A 1 801 ? 16.678 56.074 -23.744 1.00 11.69 ? 801 GLY A CA 1 ATOM 6406 C C . GLY A 1 801 ? 16.931 56.612 -22.382 1.00 12.19 ? 801 GLY A C 1 ATOM 6407 O O . GLY A 1 801 ? 16.956 57.811 -22.193 1.00 13.65 ? 801 GLY A O 1 ATOM 6408 N N . ASP A 1 802 ? 17.070 55.715 -21.418 1.00 11.59 ? 802 ASP A N 1 ATOM 6409 C CA . ASP A 1 802 ? 17.341 56.083 -20.038 1.00 11.47 ? 802 ASP A CA 1 ATOM 6410 C C . ASP A 1 802 ? 18.716 55.648 -19.587 1.00 10.59 ? 802 ASP A C 1 ATOM 6411 O O . ASP A 1 802 ? 18.990 55.674 -18.373 1.00 11.41 ? 802 ASP A O 1 ATOM 6412 C CB . ASP A 1 802 ? 16.276 55.494 -19.083 1.00 12.43 ? 802 ASP A CB 1 ATOM 6413 C CG . ASP A 1 802 ? 16.110 53.979 -19.199 1.00 12.87 ? 802 ASP A CG 1 ATOM 6414 O OD1 . ASP A 1 802 ? 16.907 53.275 -19.884 1.00 15.88 ? 802 ASP A OD1 1 ATOM 6415 O OD2 . ASP A 1 802 ? 15.126 53.506 -18.552 1.00 16.13 ? 802 ASP A OD2 1 ATOM 6416 N N . ILE A 1 803 ? 19.536 55.243 -20.520 1.00 8.87 ? 803 ILE A N 1 ATOM 6417 C CA . ILE A 1 803 ? 20.887 54.770 -20.192 1.00 9.46 ? 803 ILE A CA 1 ATOM 6418 C C . ILE A 1 803 ? 21.981 55.753 -20.501 1.00 9.14 ? 803 ILE A C 1 ATOM 6419 O O . ILE A 1 803 ? 21.933 56.439 -21.531 1.00 9.46 ? 803 ILE A O 1 ATOM 6420 C CB . ILE A 1 803 ? 21.213 53.467 -20.983 1.00 9.37 ? 803 ILE A CB 1 ATOM 6421 C CG1 . ILE A 1 803 ? 20.156 52.358 -20.645 1.00 10.80 ? 803 ILE A CG1 1 ATOM 6422 C CG2 . ILE A 1 803 ? 22.653 52.973 -20.709 1.00 9.75 ? 803 ILE A CG2 1 ATOM 6423 C CD1 . ILE A 1 803 ? 20.069 52.028 -19.149 1.00 12.81 ? 803 ILE A CD1 1 ATOM 6424 N N . PHE A 1 804 ? 22.980 55.831 -19.595 1.00 9.13 ? 804 PHE A N 1 ATOM 6425 C CA . PHE A 1 804 ? 24.169 56.647 -19.860 1.00 7.74 ? 804 PHE A CA 1 ATOM 6426 C C . PHE A 1 804 ? 25.274 56.033 -19.030 1.00 8.33 ? 804 PHE A C 1 ATOM 6427 O O . PHE A 1 804 ? 25.032 55.159 -18.213 1.00 9.29 ? 804 PHE A O 1 ATOM 6428 C CB . PHE A 1 804 ? 23.965 58.162 -19.541 1.00 8.40 ? 804 PHE A CB 1 ATOM 6429 C CG . PHE A 1 804 ? 23.544 58.480 -18.163 1.00 7.37 ? 804 PHE A CG 1 ATOM 6430 C CD1 . PHE A 1 804 ? 22.252 58.266 -17.707 1.00 8.89 ? 804 PHE A CD1 1 ATOM 6431 C CD2 . PHE A 1 804 ? 24.460 59.098 -17.287 1.00 8.12 ? 804 PHE A CD2 1 ATOM 6432 C CE1 . PHE A 1 804 ? 21.849 58.653 -16.411 1.00 8.28 ? 804 PHE A CE1 1 ATOM 6433 C CE2 . PHE A 1 804 ? 24.096 59.503 -16.004 1.00 8.52 ? 804 PHE A CE2 1 ATOM 6434 C CZ . PHE A 1 804 ? 22.797 59.297 -15.536 1.00 8.24 ? 804 PHE A CZ 1 ATOM 6435 N N . TYR A 1 805 ? 26.487 56.491 -19.265 1.00 7.85 ? 805 TYR A N 1 ATOM 6436 C CA . TYR A 1 805 ? 27.674 55.937 -18.601 1.00 8.61 ? 805 TYR A CA 1 ATOM 6437 C C . TYR A 1 805 ? 28.490 57.045 -18.053 1.00 7.94 ? 805 TYR A C 1 ATOM 6438 O O . TYR A 1 805 ? 28.665 58.077 -18.707 1.00 8.22 ? 805 TYR A O 1 ATOM 6439 C CB . TYR A 1 805 ? 28.520 55.129 -19.625 1.00 8.36 ? 805 TYR A CB 1 ATOM 6440 C CG . TYR A 1 805 ? 27.814 53.901 -20.160 1.00 7.95 ? 805 TYR A CG 1 ATOM 6441 C CD1 . TYR A 1 805 ? 26.871 54.023 -21.148 1.00 9.19 ? 805 TYR A CD1 1 ATOM 6442 C CD2 . TYR A 1 805 ? 28.109 52.655 -19.642 1.00 9.10 ? 805 TYR A CD2 1 ATOM 6443 C CE1 . TYR A 1 805 ? 26.216 52.891 -21.600 1.00 9.89 ? 805 TYR A CE1 1 ATOM 6444 C CE2 . TYR A 1 805 ? 27.451 51.479 -20.118 1.00 9.65 ? 805 TYR A CE2 1 ATOM 6445 C CZ . TYR A 1 805 ? 26.515 51.665 -21.101 1.00 9.62 ? 805 TYR A CZ 1 ATOM 6446 O OH . TYR A 1 805 ? 25.906 50.532 -21.655 1.00 11.08 ? 805 TYR A OH 1 ATOM 6447 N N . THR A 1 806 ? 28.998 56.828 -16.832 1.00 7.77 ? 806 THR A N 1 ATOM 6448 C CA . THR A 1 806 ? 29.888 57.846 -16.193 1.00 7.00 ? 806 THR A CA 1 ATOM 6449 C C . THR A 1 806 ? 31.047 57.058 -15.593 1.00 8.01 ? 806 THR A C 1 ATOM 6450 O O . THR A 1 806 ? 30.948 55.828 -15.349 1.00 7.86 ? 806 THR A O 1 ATOM 6451 C CB . THR A 1 806 ? 29.156 58.630 -15.087 1.00 7.17 ? 806 THR A CB 1 ATOM 6452 O OG1 . THR A 1 806 ? 28.772 57.731 -14.041 1.00 8.04 ? 806 THR A OG1 1 ATOM 6453 C CG2 . THR A 1 806 ? 27.868 59.300 -15.614 1.00 7.97 ? 806 THR A CG2 1 ATOM 6454 N N . ASP A 1 807 ? 32.159 57.721 -15.369 1.00 6.91 ? 807 ASP A N 1 ATOM 6455 C CA . ASP A 1 807 ? 33.289 56.986 -14.794 1.00 8.06 ? 807 ASP A CA 1 ATOM 6456 C C . ASP A 1 807 ? 33.379 57.100 -13.275 1.00 6.25 ? 807 ASP A C 1 ATOM 6457 O O . ASP A 1 807 ? 32.710 57.928 -12.637 1.00 7.00 ? 807 ASP A O 1 ATOM 6458 C CB . ASP A 1 807 ? 34.616 57.437 -15.432 1.00 9.13 ? 807 ASP A CB 1 ATOM 6459 C CG . ASP A 1 807 ? 35.054 58.776 -14.952 1.00 8.27 ? 807 ASP A CG 1 ATOM 6460 O OD1 . ASP A 1 807 ? 34.315 59.770 -15.033 1.00 9.00 ? 807 ASP A OD1 1 ATOM 6461 O OD2 . ASP A 1 807 ? 36.207 58.856 -14.436 1.00 9.78 ? 807 ASP A OD2 1 ATOM 6462 N N . LEU A 1 808 ? 34.120 56.141 -12.755 1.00 6.80 ? 808 LEU A N 1 ATOM 6463 C CA . LEU A 1 808 ? 34.405 56.110 -11.316 1.00 6.16 ? 808 LEU A CA 1 ATOM 6464 C C . LEU A 1 808 ? 35.902 56.325 -11.156 1.00 5.49 ? 808 LEU A C 1 ATOM 6465 O O . LEU A 1 808 ? 36.722 55.524 -11.607 1.00 6.66 ? 808 LEU A O 1 ATOM 6466 C CB . LEU A 1 808 ? 33.981 54.792 -10.666 1.00 7.54 ? 808 LEU A CB 1 ATOM 6467 C CG . LEU A 1 808 ? 32.442 54.679 -10.621 1.00 7.67 ? 808 LEU A CG 1 ATOM 6468 C CD1 . LEU A 1 808 ? 32.076 53.191 -10.388 1.00 9.14 ? 808 LEU A CD1 1 ATOM 6469 C CD2 . LEU A 1 808 ? 31.920 55.485 -9.433 1.00 10.24 ? 808 LEU A CD2 1 ATOM 6470 N N . ASN A 1 809 ? 36.246 57.502 -10.587 1.00 6.01 ? 809 ASN A N 1 ATOM 6471 C CA . ASN A 1 809 ? 37.646 57.853 -10.262 1.00 5.86 ? 809 ASN A CA 1 ATOM 6472 C C . ASN A 1 809 ? 38.625 57.754 -11.404 1.00 6.05 ? 809 ASN A C 1 ATOM 6473 O O . ASN A 1 809 ? 39.798 57.482 -11.216 1.00 6.74 ? 809 ASN A O 1 ATOM 6474 C CB . ASN A 1 809 ? 38.137 56.958 -9.087 1.00 5.91 ? 809 ASN A CB 1 ATOM 6475 C CG . ASN A 1 809 ? 37.087 56.856 -8.003 1.00 6.01 ? 809 ASN A CG 1 ATOM 6476 O OD1 . ASN A 1 809 ? 36.232 55.938 -8.015 1.00 6.55 ? 809 ASN A OD1 1 ATOM 6477 N ND2 . ASN A 1 809 ? 37.110 57.809 -7.070 1.00 7.04 ? 809 ASN A ND2 1 ATOM 6478 N N . GLY A 1 810 ? 38.141 57.964 -12.636 1.00 6.14 ? 810 GLY A N 1 ATOM 6479 C CA . GLY A 1 810 ? 39.064 57.880 -13.793 1.00 7.43 ? 810 GLY A CA 1 ATOM 6480 C C . GLY A 1 810 ? 39.553 56.452 -14.071 1.00 8.23 ? 810 GLY A C 1 ATOM 6481 O O . GLY A 1 810 ? 40.490 56.282 -14.869 1.00 9.52 ? 810 GLY A O 1 ATOM 6482 N N . LEU A 1 811 ? 38.925 55.449 -13.443 1.00 6.89 ? 811 LEU A N 1 ATOM 6483 C CA . LEU A 1 811 ? 39.372 54.059 -13.527 1.00 8.06 ? 811 LEU A CA 1 ATOM 6484 C C . LEU A 1 811 ? 38.489 53.164 -14.377 1.00 8.86 ? 811 LEU A C 1 ATOM 6485 O O . LEU A 1 811 ? 38.995 52.282 -15.083 1.00 10.43 ? 811 LEU A O 1 ATOM 6486 C CB . LEU A 1 811 ? 39.439 53.479 -12.092 1.00 8.88 ? 811 LEU A CB 1 ATOM 6487 C CG . LEU A 1 811 ? 39.839 51.999 -11.987 1.00 9.98 ? 811 LEU A CG 1 ATOM 6488 C CD1 . LEU A 1 811 ? 41.276 51.831 -12.473 1.00 11.29 ? 811 LEU A CD1 1 ATOM 6489 C CD2 . LEU A 1 811 ? 39.709 51.545 -10.537 1.00 10.56 ? 811 LEU A CD2 1 ATOM 6490 N N . GLN A 1 812 ? 37.182 53.394 -14.327 1.00 7.29 ? 812 GLN A N 1 ATOM 6491 C CA . GLN A 1 812 ? 36.249 52.479 -14.992 1.00 7.48 ? 812 GLN A CA 1 ATOM 6492 C C . GLN A 1 812 ? 34.957 53.213 -15.330 1.00 7.59 ? 812 GLN A C 1 ATOM 6493 O O . GLN A 1 812 ? 34.636 54.231 -14.668 1.00 8.87 ? 812 GLN A O 1 ATOM 6494 C CB . GLN A 1 812 ? 35.915 51.310 -14.041 1.00 8.98 ? 812 GLN A CB 1 ATOM 6495 C CG . GLN A 1 812 ? 35.295 51.815 -12.728 1.00 11.03 ? 812 GLN A CG 1 ATOM 6496 C CD . GLN A 1 812 ? 35.022 50.687 -11.735 1.00 11.92 ? 812 GLN A CD 1 ATOM 6497 O OE1 . GLN A 1 812 ? 34.058 49.931 -11.882 1.00 12.14 ? 812 GLN A OE1 1 ATOM 6498 N NE2 . GLN A 1 812 ? 35.824 50.617 -10.678 1.00 13.40 ? 812 GLN A NE2 1 ATOM 6499 N N . PHE A 1 813 ? 34.216 52.752 -16.335 1.00 7.93 ? 813 PHE A N 1 ATOM 6500 C CA . PHE A 1 813 ? 32.924 53.364 -16.657 1.00 7.49 ? 813 PHE A CA 1 ATOM 6501 C C . PHE A 1 813 ? 31.809 52.440 -16.211 1.00 7.58 ? 813 PHE A C 1 ATOM 6502 O O . PHE A 1 813 ? 31.828 51.195 -16.498 1.00 9.52 ? 813 PHE A O 1 ATOM 6503 C CB . PHE A 1 813 ? 32.856 53.653 -18.161 1.00 7.74 ? 813 PHE A CB 1 ATOM 6504 C CG . PHE A 1 813 ? 33.620 54.878 -18.558 1.00 8.19 ? 813 PHE A CG 1 ATOM 6505 C CD1 . PHE A 1 813 ? 35.000 54.839 -18.633 1.00 8.55 ? 813 PHE A CD1 1 ATOM 6506 C CD2 . PHE A 1 813 ? 32.940 56.109 -18.771 1.00 8.35 ? 813 PHE A CD2 1 ATOM 6507 C CE1 . PHE A 1 813 ? 35.720 56.029 -18.892 1.00 10.36 ? 813 PHE A CE1 1 ATOM 6508 C CE2 . PHE A 1 813 ? 33.678 57.267 -19.039 1.00 9.61 ? 813 PHE A CE2 1 ATOM 6509 C CZ . PHE A 1 813 ? 35.044 57.204 -19.090 1.00 9.89 ? 813 PHE A CZ 1 ATOM 6510 N N . ILE A 1 814 ? 30.840 53.017 -15.534 1.00 6.62 ? 814 ILE A N 1 ATOM 6511 C CA . ILE A 1 814 ? 29.745 52.226 -15.003 1.00 8.04 ? 814 ILE A CA 1 ATOM 6512 C C . ILE A 1 814 ? 28.438 52.665 -15.695 1.00 7.86 ? 814 ILE A C 1 ATOM 6513 O O . ILE A 1 814 ? 28.212 53.855 -15.954 1.00 7.85 ? 814 ILE A O 1 ATOM 6514 C CB . ILE A 1 814 ? 29.693 52.421 -13.448 1.00 7.65 ? 814 ILE A CB 1 ATOM 6515 C CG1 . ILE A 1 814 ? 28.627 51.504 -12.856 1.00 8.10 ? 814 ILE A CG1 1 ATOM 6516 C CG2 . ILE A 1 814 ? 29.429 53.883 -13.044 1.00 8.17 ? 814 ILE A CG2 1 ATOM 6517 C CD1 . ILE A 1 814 ? 28.773 51.337 -11.292 1.00 8.96 ? 814 ILE A CD1 1 ATOM 6518 N N . LYS A 1 815 ? 27.597 51.670 -16.011 1.00 8.00 ? 815 LYS A N 1 ATOM 6519 C CA . LYS A 1 815 ? 26.289 51.980 -16.593 1.00 8.31 ? 815 LYS A CA 1 ATOM 6520 C C . LYS A 1 815 ? 25.372 52.595 -15.551 1.00 7.66 ? 815 LYS A C 1 ATOM 6521 O O . LYS A 1 815 ? 25.233 52.124 -14.423 1.00 8.17 ? 815 LYS A O 1 ATOM 6522 C CB . LYS A 1 815 ? 25.672 50.658 -17.118 1.00 9.34 ? 815 LYS A CB 1 ATOM 6523 C CG . LYS A 1 815 ? 24.371 50.826 -17.887 1.00 10.45 ? 815 LYS A CG 1 ATOM 6524 C CD . LYS A 1 815 ? 23.998 49.417 -18.442 1.00 13.49 ? 815 LYS A CD 1 ATOM 6525 C CE . LYS A 1 815 ? 22.866 49.426 -19.429 1.00 17.49 ? 815 LYS A CE 1 ATOM 6526 N NZ . LYS A 1 815 ? 22.541 48.007 -19.806 1.00 19.16 ? 815 LYS A NZ 1 ATOM 6527 N N . ARG A 1 816 ? 24.724 53.680 -15.952 1.00 7.73 ? 816 ARG A N 1 ATOM 6528 C CA . ARG A 1 816 ? 23.724 54.360 -15.183 1.00 7.82 ? 816 ARG A CA 1 ATOM 6529 C C . ARG A 1 816 ? 22.349 54.252 -15.855 1.00 8.47 ? 816 ARG A C 1 ATOM 6530 O O . ARG A 1 816 ? 22.284 54.205 -17.104 1.00 8.38 ? 816 ARG A O 1 ATOM 6531 C CB . ARG A 1 816 ? 23.984 55.890 -15.059 1.00 8.13 ? 816 ARG A CB 1 ATOM 6532 C CG . ARG A 1 816 ? 25.426 56.218 -14.546 1.00 7.87 ? 816 ARG A CG 1 ATOM 6533 C CD . ARG A 1 816 ? 25.626 55.637 -13.163 1.00 8.02 ? 816 ARG A CD 1 ATOM 6534 N NE . ARG A 1 816 ? 26.842 56.196 -12.538 1.00 7.36 ? 816 ARG A NE 1 ATOM 6535 C CZ . ARG A 1 816 ? 27.224 55.792 -11.327 1.00 7.96 ? 816 ARG A CZ 1 ATOM 6536 N NH1 . ARG A 1 816 ? 26.509 54.876 -10.699 1.00 7.69 ? 816 ARG A NH1 1 ATOM 6537 N NH2 . ARG A 1 816 ? 28.275 56.372 -10.713 1.00 8.39 ? 816 ARG A NH2 1 ATOM 6538 N N . ARG A 1 817 ? 21.297 54.196 -15.028 1.00 8.16 ? 817 ARG A N 1 ATOM 6539 C CA . ARG A 1 817 ? 19.941 54.252 -15.621 1.00 8.12 ? 817 ARG A CA 1 ATOM 6540 C C . ARG A 1 817 ? 19.222 55.385 -14.933 1.00 8.67 ? 817 ARG A C 1 ATOM 6541 O O . ARG A 1 817 ? 19.107 55.429 -13.694 1.00 9.23 ? 817 ARG A O 1 ATOM 6542 C CB . ARG A 1 817 ? 19.230 52.917 -15.386 1.00 9.61 ? 817 ARG A CB 1 ATOM 6543 C CG . ARG A 1 817 ? 17.747 52.933 -15.788 1.00 10.97 ? 817 ARG A CG 1 ATOM 6544 C CD . ARG A 1 817 ? 17.069 51.530 -15.654 1.00 12.20 ? 817 ARG A CD 1 ATOM 6545 N NE . ARG A 1 817 ? 17.626 50.508 -16.540 1.00 12.19 ? 817 ARG A NE 1 ATOM 6546 C CZ . ARG A 1 817 ? 18.398 49.510 -16.138 1.00 12.74 ? 817 ARG A CZ 1 ATOM 6547 N NH1 . ARG A 1 817 ? 18.726 49.386 -14.837 1.00 12.99 ? 817 ARG A NH1 1 ATOM 6548 N NH2 . ARG A 1 817 ? 18.843 48.621 -17.021 1.00 15.88 ? 817 ARG A NH2 1 ATOM 6549 N N . ARG A 1 818 ? 18.757 56.340 -15.750 1.00 8.66 ? 818 ARG A N 1 ATOM 6550 C CA . ARG A 1 818 ? 17.983 57.469 -15.251 1.00 9.46 ? 818 ARG A CA 1 ATOM 6551 C C . ARG A 1 818 ? 16.669 56.885 -14.726 1.00 9.72 ? 818 ARG A C 1 ATOM 6552 O O A ARG A 1 818 ? 16.009 56.133 -15.452 0.50 11.51 ? 818 ARG A O 1 ATOM 6553 O O B ARG A 1 818 ? 16.124 55.930 -15.320 0.50 11.07 ? 818 ARG A O 1 ATOM 6554 C CB . ARG A 1 818 ? 17.699 58.428 -16.413 1.00 9.97 ? 818 ARG A CB 1 ATOM 6555 C CG A ARG A 1 818 ? 17.072 59.737 -15.963 0.50 10.07 ? 818 ARG A CG 1 ATOM 6556 C CG B ARG A 1 818 ? 16.721 59.587 -15.929 0.50 11.56 ? 818 ARG A CG 1 ATOM 6557 C CD . ARG A 1 818 ? 16.335 60.433 -17.105 1.00 10.03 ? 818 ARG A CD 1 ATOM 6558 N NE A ARG A 1 818 ? 15.037 59.798 -17.366 0.50 10.04 ? 818 ARG A NE 1 ATOM 6559 N NE B ARG A 1 818 ? 17.161 60.373 -18.192 0.50 14.85 ? 818 ARG A NE 1 ATOM 6560 C CZ A ARG A 1 818 ? 14.679 59.242 -18.516 0.50 10.21 ? 818 ARG A CZ 1 ATOM 6561 C CZ B ARG A 1 818 ? 16.999 59.792 -19.384 0.50 13.61 ? 818 ARG A CZ 1 ATOM 6562 N NH1 A ARG A 1 818 ? 15.483 59.220 -19.552 0.50 11.06 ? 818 ARG A NH1 1 ATOM 6563 N NH1 B ARG A 1 818 ? 15.845 59.188 -19.726 0.50 15.56 ? 818 ARG A NH1 1 ATOM 6564 N NH2 A ARG A 1 818 ? 13.493 58.656 -18.609 0.50 10.63 ? 818 ARG A NH2 1 ATOM 6565 N NH2 B ARG A 1 818 ? 18.066 59.706 -20.180 0.50 10.31 ? 818 ARG A NH2 1 ATOM 6566 N N . LEU A 1 819 ? 16.306 57.241 -13.503 1.00 9.86 ? 819 LEU A N 1 ATOM 6567 C CA . LEU A 1 819 ? 15.086 56.702 -12.844 1.00 11.99 ? 819 LEU A CA 1 ATOM 6568 C C . LEU A 1 819 ? 14.140 57.863 -12.575 1.00 11.47 ? 819 LEU A C 1 ATOM 6569 O O . LEU A 1 819 ? 14.387 58.747 -11.731 1.00 12.00 ? 819 LEU A O 1 ATOM 6570 C CB . LEU A 1 819 ? 15.466 55.991 -11.527 1.00 12.58 ? 819 LEU A CB 1 ATOM 6571 C CG . LEU A 1 819 ? 16.408 54.768 -11.679 1.00 12.81 ? 819 LEU A CG 1 ATOM 6572 C CD1 . LEU A 1 819 ? 16.816 54.262 -10.314 1.00 15.34 ? 819 LEU A CD1 1 ATOM 6573 C CD2 . LEU A 1 819 ? 15.745 53.698 -12.514 1.00 14.86 ? 819 LEU A CD2 1 ATOM 6574 N N . ASP A 1 820 ? 13.019 57.843 -13.315 1.00 12.59 ? 820 ASP A N 1 ATOM 6575 C CA . ASP A 1 820 ? 12.067 58.904 -13.120 1.00 13.86 ? 820 ASP A CA 1 ATOM 6576 C C . ASP A 1 820 ? 11.348 58.780 -11.777 1.00 12.74 ? 820 ASP A C 1 ATOM 6577 O O . ASP A 1 820 ? 10.722 59.738 -11.312 1.00 13.69 ? 820 ASP A O 1 ATOM 6578 C CB . ASP A 1 820 ? 11.099 58.945 -14.289 1.00 16.16 ? 820 ASP A CB 1 ATOM 6579 C CG . ASP A 1 820 ? 11.794 59.305 -15.600 1.00 16.99 ? 820 ASP A CG 1 ATOM 6580 O OD1 . ASP A 1 820 ? 12.908 59.912 -15.604 1.00 17.87 ? 820 ASP A OD1 1 ATOM 6581 O OD2 . ASP A 1 820 ? 11.232 58.994 -16.677 1.00 20.10 ? 820 ASP A OD2 1 ATOM 6582 N N . LYS A 1 821 ? 11.470 57.627 -11.110 1.00 11.37 ? 821 LYS A N 1 ATOM 6583 C CA . LYS A 1 821 ? 10.879 57.509 -9.783 1.00 12.95 ? 821 LYS A CA 1 ATOM 6584 C C . LYS A 1 821 ? 11.699 58.238 -8.706 1.00 13.42 ? 821 LYS A C 1 ATOM 6585 O O . LYS A 1 821 ? 11.274 58.380 -7.569 1.00 15.26 ? 821 LYS A O 1 ATOM 6586 C CB . LYS A 1 821 ? 10.703 56.039 -9.364 1.00 13.19 ? 821 LYS A CB 1 ATOM 6587 C CG . LYS A 1 821 ? 12.052 55.315 -9.107 1.00 12.34 ? 821 LYS A CG 1 ATOM 6588 C CD . LYS A 1 821 ? 11.867 53.812 -9.083 1.00 13.38 ? 821 LYS A CD 1 ATOM 6589 C CE . LYS A 1 821 ? 13.225 53.143 -8.918 1.00 12.36 ? 821 LYS A CE 1 ATOM 6590 N NZ . LYS A 1 821 ? 13.197 51.688 -9.180 1.00 12.90 ? 821 LYS A NZ 1 ATOM 6591 N N . LEU A 1 822 ? 12.889 58.714 -9.089 1.00 11.75 ? 822 LEU A N 1 ATOM 6592 C CA . LEU A 1 822 ? 13.717 59.479 -8.146 1.00 12.29 ? 822 LEU A CA 1 ATOM 6593 C C . LEU A 1 822 ? 13.743 60.922 -8.656 1.00 12.18 ? 822 LEU A C 1 ATOM 6594 O O . LEU A 1 822 ? 13.571 61.162 -9.847 1.00 12.21 ? 822 LEU A O 1 ATOM 6595 C CB . LEU A 1 822 ? 15.158 58.935 -8.144 1.00 13.03 ? 822 LEU A CB 1 ATOM 6596 C CG . LEU A 1 822 ? 15.295 57.465 -7.683 1.00 13.62 ? 822 LEU A CG 1 ATOM 6597 C CD1 . LEU A 1 822 ? 16.780 57.094 -7.704 1.00 14.73 ? 822 LEU A CD1 1 ATOM 6598 C CD2 . LEU A 1 822 ? 14.645 57.207 -6.314 1.00 14.35 ? 822 LEU A CD2 1 ATOM 6599 N N . PRO A 1 823 ? 14.008 61.881 -7.754 1.00 11.51 ? 823 PRO A N 1 ATOM 6600 C CA . PRO A 1 823 ? 14.067 63.296 -8.173 1.00 11.16 ? 823 PRO A CA 1 ATOM 6601 C C . PRO A 1 823 ? 15.286 63.587 -9.040 1.00 10.88 ? 823 PRO A C 1 ATOM 6602 O O . PRO A 1 823 ? 16.267 62.802 -9.082 1.00 11.44 ? 823 PRO A O 1 ATOM 6603 C CB . PRO A 1 823 ? 14.087 64.084 -6.868 1.00 12.75 ? 823 PRO A CB 1 ATOM 6604 C CG . PRO A 1 823 ? 14.668 63.138 -5.857 1.00 13.88 ? 823 PRO A CG 1 ATOM 6605 C CD . PRO A 1 823 ? 14.221 61.710 -6.310 1.00 12.19 ? 823 PRO A CD 1 ATOM 6606 N N . LEU A 1 824 ? 15.220 64.703 -9.769 1.00 10.63 ? 824 LEU A N 1 ATOM 6607 C CA . LEU A 1 824 ? 16.275 65.094 -10.670 1.00 9.76 ? 824 LEU A CA 1 ATOM 6608 C C . LEU A 1 824 ? 17.702 64.978 -10.059 1.00 9.16 ? 824 LEU A C 1 ATOM 6609 O O . LEU A 1 824 ? 18.575 64.369 -10.698 1.00 9.33 ? 824 LEU A O 1 ATOM 6610 C CB . LEU A 1 824 ? 15.947 66.536 -11.162 1.00 11.13 ? 824 LEU A CB 1 ATOM 6611 C CG . LEU A 1 824 ? 16.747 67.143 -12.306 1.00 10.07 ? 824 LEU A CG 1 ATOM 6612 C CD1 . LEU A 1 824 ? 15.980 68.426 -12.801 1.00 12.26 ? 824 LEU A CD1 1 ATOM 6613 C CD2 . LEU A 1 824 ? 18.250 67.546 -11.907 1.00 10.46 ? 824 LEU A CD2 1 ATOM 6614 N N . GLN A 1 825 ? 17.876 65.541 -8.865 1.00 9.05 ? 825 GLN A N 1 ATOM 6615 C CA . GLN A 1 825 ? 19.199 65.532 -8.227 1.00 9.10 ? 825 GLN A CA 1 ATOM 6616 C C . GLN A 1 825 ? 19.698 64.124 -7.939 1.00 9.26 ? 825 GLN A C 1 ATOM 6617 O O . GLN A 1 825 ? 20.948 63.950 -7.808 1.00 9.09 ? 825 GLN A O 1 ATOM 6618 C CB . GLN A 1 825 ? 19.185 66.413 -6.968 1.00 9.95 ? 825 GLN A CB 1 ATOM 6619 C CG . GLN A 1 825 ? 18.261 65.890 -5.842 1.00 9.63 ? 825 GLN A CG 1 ATOM 6620 C CD . GLN A 1 825 ? 16.802 66.371 -5.952 1.00 9.38 ? 825 GLN A CD 1 ATOM 6621 O OE1 . GLN A 1 825 ? 16.351 66.828 -6.976 1.00 10.92 ? 825 GLN A OE1 1 ATOM 6622 N NE2 . GLN A 1 825 ? 16.105 66.263 -4.866 1.00 10.90 ? 825 GLN A NE2 1 ATOM 6623 N N . ALA A 1 826 ? 18.814 63.116 -7.833 1.00 9.02 ? 826 ALA A N 1 ATOM 6624 C CA . ALA A 1 826 ? 19.282 61.739 -7.588 1.00 8.23 ? 826 ALA A CA 1 ATOM 6625 C C . ALA A 1 826 ? 19.863 61.154 -8.864 1.00 8.76 ? 826 ALA A C 1 ATOM 6626 O O . ALA A 1 826 ? 20.619 60.182 -8.823 1.00 9.32 ? 826 ALA A O 1 ATOM 6627 C CB . ALA A 1 826 ? 18.089 60.867 -7.121 1.00 9.02 ? 826 ALA A CB 1 ATOM 6628 N N . ASN A 1 827 ? 19.515 61.715 -10.026 1.00 8.26 ? 827 ASN A N 1 ATOM 6629 C CA . ASN A 1 827 ? 20.004 61.235 -11.331 1.00 9.11 ? 827 ASN A CA 1 ATOM 6630 C C . ASN A 1 827 ? 21.314 61.880 -11.772 1.00 8.51 ? 827 ASN A C 1 ATOM 6631 O O . ASN A 1 827 ? 21.839 61.607 -12.830 1.00 8.97 ? 827 ASN A O 1 ATOM 6632 C CB . ASN A 1 827 ? 18.885 61.382 -12.380 1.00 9.79 ? 827 ASN A CB 1 ATOM 6633 C CG . ASN A 1 827 ? 17.770 60.368 -12.140 1.00 10.75 ? 827 ASN A CG 1 ATOM 6634 O OD1 . ASN A 1 827 ? 18.001 59.155 -12.183 1.00 11.06 ? 827 ASN A OD1 1 ATOM 6635 N ND2 . ASN A 1 827 ? 16.582 60.862 -11.841 1.00 12.25 ? 827 ASN A ND2 1 ATOM 6636 N N . TYR A 1 828 ? 21.801 62.741 -10.886 1.00 8.29 ? 828 TYR A N 1 ATOM 6637 C CA . TYR A 1 828 ? 23.147 63.361 -11.053 1.00 7.77 ? 828 TYR A CA 1 ATOM 6638 C C . TYR A 1 828 ? 24.174 62.424 -10.421 1.00 7.04 ? 828 TYR A C 1 ATOM 6639 O O . TYR A 1 828 ? 23.951 61.901 -9.330 1.00 8.30 ? 828 TYR A O 1 ATOM 6640 C CB . TYR A 1 828 ? 23.195 64.738 -10.348 1.00 8.80 ? 828 TYR A CB 1 ATOM 6641 C CG . TYR A 1 828 ? 23.227 65.883 -11.328 1.00 7.54 ? 828 TYR A CG 1 ATOM 6642 C CD1 . TYR A 1 828 ? 22.187 66.084 -12.248 1.00 8.71 ? 828 TYR A CD1 1 ATOM 6643 C CD2 . TYR A 1 828 ? 24.316 66.739 -11.392 1.00 8.92 ? 828 TYR A CD2 1 ATOM 6644 C CE1 . TYR A 1 828 ? 22.241 67.094 -13.208 1.00 9.32 ? 828 TYR A CE1 1 ATOM 6645 C CE2 . TYR A 1 828 ? 24.368 67.725 -12.353 1.00 9.81 ? 828 TYR A CE2 1 ATOM 6646 C CZ . TYR A 1 828 ? 23.341 67.896 -13.248 1.00 8.41 ? 828 TYR A CZ 1 ATOM 6647 O OH . TYR A 1 828 ? 23.466 68.917 -14.184 1.00 9.94 ? 828 TYR A OH 1 ATOM 6648 N N . TYR A 1 829 ? 25.274 62.252 -11.151 1.00 7.29 ? 829 TYR A N 1 ATOM 6649 C CA . TYR A 1 829 ? 26.369 61.375 -10.749 1.00 7.87 ? 829 TYR A CA 1 ATOM 6650 C C . TYR A 1 829 ? 27.696 62.078 -10.898 1.00 8.45 ? 829 TYR A C 1 ATOM 6651 O O . TYR A 1 829 ? 27.792 63.089 -11.558 1.00 8.16 ? 829 TYR A O 1 ATOM 6652 C CB . TYR A 1 829 ? 26.403 60.125 -11.647 1.00 7.92 ? 829 TYR A CB 1 ATOM 6653 C CG . TYR A 1 829 ? 25.262 59.204 -11.356 1.00 7.71 ? 829 TYR A CG 1 ATOM 6654 C CD1 . TYR A 1 829 ? 25.321 58.310 -10.297 1.00 7.45 ? 829 TYR A CD1 1 ATOM 6655 C CD2 . TYR A 1 829 ? 24.078 59.261 -12.119 1.00 7.94 ? 829 TYR A CD2 1 ATOM 6656 C CE1 . TYR A 1 829 ? 24.202 57.485 -9.961 1.00 7.92 ? 829 TYR A CE1 1 ATOM 6657 C CE2 . TYR A 1 829 ? 22.998 58.428 -11.814 1.00 9.10 ? 829 TYR A CE2 1 ATOM 6658 C CZ . TYR A 1 829 ? 23.072 57.556 -10.735 1.00 8.29 ? 829 TYR A CZ 1 ATOM 6659 O OH . TYR A 1 829 ? 22.016 56.731 -10.419 1.00 9.38 ? 829 TYR A OH 1 ATOM 6660 N N . PRO A 1 830 ? 28.729 61.586 -10.211 1.00 8.09 ? 830 PRO A N 1 ATOM 6661 C CA . PRO A 1 830 ? 30.040 62.223 -10.381 1.00 7.50 ? 830 PRO A CA 1 ATOM 6662 C C . PRO A 1 830 ? 30.507 61.997 -11.833 1.00 7.18 ? 830 PRO A C 1 ATOM 6663 O O . PRO A 1 830 ? 30.300 60.906 -12.393 1.00 7.61 ? 830 PRO A O 1 ATOM 6664 C CB . PRO A 1 830 ? 30.951 61.398 -9.439 1.00 10.98 ? 830 PRO A CB 1 ATOM 6665 C CG . PRO A 1 830 ? 30.039 60.663 -8.508 1.00 9.77 ? 830 PRO A CG 1 ATOM 6666 C CD . PRO A 1 830 ? 28.723 60.478 -9.235 1.00 7.80 ? 830 PRO A CD 1 ATOM 6667 N N . ILE A 1 831 ? 31.114 63.002 -12.463 1.00 7.00 ? 831 ILE A N 1 ATOM 6668 C CA . ILE A 1 831 ? 31.768 62.847 -13.764 1.00 7.40 ? 831 ILE A CA 1 ATOM 6669 C C . ILE A 1 831 ? 33.252 63.155 -13.475 1.00 7.45 ? 831 ILE A C 1 ATOM 6670 O O . ILE A 1 831 ? 33.791 64.241 -13.801 1.00 7.65 ? 831 ILE A O 1 ATOM 6671 C CB . ILE A 1 831 ? 31.204 63.837 -14.823 1.00 6.79 ? 831 ILE A CB 1 ATOM 6672 C CG1 . ILE A 1 831 ? 29.673 63.873 -14.832 1.00 7.95 ? 831 ILE A CG1 1 ATOM 6673 C CG2 . ILE A 1 831 ? 31.709 63.394 -16.218 1.00 8.10 ? 831 ILE A CG2 1 ATOM 6674 C CD1 . ILE A 1 831 ? 28.961 62.576 -15.162 1.00 8.31 ? 831 ILE A CD1 1 ATOM 6675 N N . PRO A 1 832 ? 33.978 62.194 -12.894 1.00 6.92 ? 832 PRO A N 1 ATOM 6676 C CA . PRO A 1 832 ? 35.390 62.508 -12.579 1.00 7.26 ? 832 PRO A CA 1 ATOM 6677 C C . PRO A 1 832 ? 36.288 62.615 -13.772 1.00 8.01 ? 832 PRO A C 1 ATOM 6678 O O . PRO A 1 832 ? 37.242 63.380 -13.674 1.00 9.70 ? 832 PRO A O 1 ATOM 6679 C CB . PRO A 1 832 ? 35.786 61.427 -11.544 1.00 7.25 ? 832 PRO A CB 1 ATOM 6680 C CG . PRO A 1 832 ? 34.788 60.333 -11.775 1.00 8.40 ? 832 PRO A CG 1 ATOM 6681 C CD . PRO A 1 832 ? 33.500 61.012 -12.160 1.00 7.62 ? 832 PRO A CD 1 ATOM 6682 N N . SER A 1 833 ? 35.968 61.965 -14.890 1.00 7.15 ? 833 SER A N 1 ATOM 6683 C CA . SER A 1 833 ? 36.787 62.113 -16.069 1.00 7.39 ? 833 SER A CA 1 ATOM 6684 C C . SER A 1 833 ? 36.013 61.924 -17.387 1.00 7.28 ? 833 SER A C 1 ATOM 6685 O O . SER A 1 833 ? 36.549 62.262 -18.444 1.00 6.87 ? 833 SER A O 1 ATOM 6686 C CB . SER A 1 833 ? 38.006 61.178 -16.048 1.00 8.93 ? 833 SER A CB 1 ATOM 6687 O OG . SER A 1 833 ? 37.721 59.864 -16.326 1.00 10.49 ? 833 SER A OG 1 ATOM 6688 N N . GLY A 1 834 ? 34.791 61.376 -17.329 1.00 7.01 ? 834 GLY A N 1 ATOM 6689 C CA . GLY A 1 834 ? 34.088 61.272 -18.630 1.00 7.37 ? 834 GLY A CA 1 ATOM 6690 C C . GLY A 1 834 ? 32.725 60.668 -18.498 1.00 6.61 ? 834 GLY A C 1 ATOM 6691 O O . GLY A 1 834 ? 32.341 60.090 -17.485 1.00 7.28 ? 834 GLY A O 1 ATOM 6692 N N . MET A 1 835 ? 31.948 60.835 -19.560 1.00 6.97 ? 835 MET A N 1 ATOM 6693 C CA . MET A 1 835 ? 30.575 60.288 -19.598 1.00 7.70 ? 835 MET A CA 1 ATOM 6694 C C . MET A 1 835 ? 30.220 60.066 -21.057 1.00 7.60 ? 835 MET A C 1 ATOM 6695 O O . MET A 1 835 ? 30.813 60.701 -21.960 1.00 8.48 ? 835 MET A O 1 ATOM 6696 C CB . MET A 1 835 ? 29.593 61.287 -18.986 1.00 8.05 ? 835 MET A CB 1 ATOM 6697 C CG . MET A 1 835 ? 29.479 62.627 -19.752 1.00 9.64 ? 835 MET A CG 1 ATOM 6698 S SD . MET A 1 835 ? 28.620 63.916 -18.847 1.00 11.05 ? 835 MET A SD 1 ATOM 6699 C CE . MET A 1 835 ? 27.175 63.179 -18.390 1.00 12.41 ? 835 MET A CE 1 ATOM 6700 N N . PHE A 1 836 ? 29.285 59.147 -21.297 1.00 7.08 ? 836 PHE A N 1 ATOM 6701 C CA . PHE A 1 836 ? 28.858 58.930 -22.694 1.00 8.06 ? 836 PHE A CA 1 ATOM 6702 C C . PHE A 1 836 ? 27.466 58.367 -22.761 1.00 8.30 ? 836 PHE A C 1 ATOM 6703 O O . PHE A 1 836 ? 26.908 57.835 -21.788 1.00 8.17 ? 836 PHE A O 1 ATOM 6704 C CB . PHE A 1 836 ? 29.882 58.071 -23.488 1.00 8.61 ? 836 PHE A CB 1 ATOM 6705 C CG . PHE A 1 836 ? 30.052 56.612 -23.039 1.00 9.00 ? 836 PHE A CG 1 ATOM 6706 C CD1 . PHE A 1 836 ? 29.170 55.627 -23.503 1.00 9.39 ? 836 PHE A CD1 1 ATOM 6707 C CD2 . PHE A 1 836 ? 31.138 56.239 -22.245 1.00 8.45 ? 836 PHE A CD2 1 ATOM 6708 C CE1 . PHE A 1 836 ? 29.392 54.278 -23.172 1.00 10.22 ? 836 PHE A CE1 1 ATOM 6709 C CE2 . PHE A 1 836 ? 31.360 54.893 -21.933 1.00 9.87 ? 836 PHE A CE2 1 ATOM 6710 C CZ . PHE A 1 836 ? 30.499 53.911 -22.399 1.00 9.66 ? 836 PHE A CZ 1 ATOM 6711 N N . ILE A 1 837 ? 26.880 58.592 -23.956 1.00 8.64 ? 837 ILE A N 1 ATOM 6712 C CA . ILE A 1 837 ? 25.559 57.994 -24.295 1.00 9.61 ? 837 ILE A CA 1 ATOM 6713 C C . ILE A 1 837 ? 25.738 57.325 -25.635 1.00 9.13 ? 837 ILE A C 1 ATOM 6714 O O . ILE A 1 837 ? 26.578 57.708 -26.431 1.00 9.22 ? 837 ILE A O 1 ATOM 6715 C CB . ILE A 1 837 ? 24.389 59.024 -24.399 1.00 10.41 ? 837 ILE A CB 1 ATOM 6716 C CG1 . ILE A 1 837 ? 24.847 60.253 -25.211 1.00 9.65 ? 837 ILE A CG1 1 ATOM 6717 C CG2 . ILE A 1 837 ? 23.862 59.337 -23.045 1.00 11.02 ? 837 ILE A CG2 1 ATOM 6718 C CD1 . ILE A 1 837 ? 23.601 61.108 -25.662 1.00 11.73 ? 837 ILE A CD1 1 ATOM 6719 N N . GLU A 1 838 ? 24.944 56.284 -25.861 1.00 9.74 ? 838 GLU A N 1 ATOM 6720 C CA . GLU A 1 838 ? 25.041 55.593 -27.159 1.00 10.23 ? 838 GLU A CA 1 ATOM 6721 C C . GLU A 1 838 ? 23.752 54.855 -27.471 1.00 10.24 ? 838 GLU A C 1 ATOM 6722 O O . GLU A 1 838 ? 22.888 54.649 -26.648 1.00 11.08 ? 838 GLU A O 1 ATOM 6723 C CB . GLU A 1 838 ? 26.165 54.560 -27.156 1.00 10.84 ? 838 GLU A CB 1 ATOM 6724 C CG . GLU A 1 838 ? 25.947 53.416 -26.114 1.00 11.28 ? 838 GLU A CG 1 ATOM 6725 C CD . GLU A 1 838 ? 27.055 52.363 -26.106 1.00 11.95 ? 838 GLU A CD 1 ATOM 6726 O OE1 . GLU A 1 838 ? 28.079 52.507 -26.794 1.00 14.36 ? 838 GLU A OE1 1 ATOM 6727 O OE2 . GLU A 1 838 ? 26.914 51.314 -25.417 1.00 14.09 ? 838 GLU A OE2 1 ATOM 6728 N N . ASP A 1 839 ? 23.633 54.559 -28.765 1.00 10.27 ? 839 ASP A N 1 ATOM 6729 C CA . ASP A 1 839 ? 22.517 53.678 -29.220 1.00 11.34 ? 839 ASP A CA 1 ATOM 6730 C C . ASP A 1 839 ? 23.221 52.598 -30.026 1.00 12.28 ? 839 ASP A C 1 ATOM 6731 O O . ASP A 1 839 ? 24.441 52.376 -29.932 1.00 13.00 ? 839 ASP A O 1 ATOM 6732 C CB . ASP A 1 839 ? 21.418 54.423 -30.006 1.00 11.56 ? 839 ASP A CB 1 ATOM 6733 C CG . ASP A 1 839 ? 21.917 55.144 -31.276 1.00 11.55 ? 839 ASP A CG 1 ATOM 6734 O OD1 . ASP A 1 839 ? 22.922 54.738 -31.872 1.00 11.92 ? 839 ASP A OD1 1 ATOM 6735 O OD2 . ASP A 1 839 ? 21.197 56.142 -31.584 1.00 15.02 ? 839 ASP A OD2 1 ATOM 6736 N N . ALA A 1 840 ? 22.461 51.864 -30.859 1.00 13.25 ? 840 ALA A N 1 ATOM 6737 C CA . ALA A 1 840 ? 23.091 50.819 -31.594 1.00 14.13 ? 840 ALA A CA 1 ATOM 6738 C C . ALA A 1 840 ? 24.208 51.258 -32.534 1.00 13.53 ? 840 ALA A C 1 ATOM 6739 O O . ALA A 1 840 ? 25.181 50.547 -32.777 1.00 15.27 ? 840 ALA A O 1 ATOM 6740 C CB . ALA A 1 840 ? 22.018 50.052 -32.405 1.00 15.57 ? 840 ALA A CB 1 ATOM 6741 N N . ASN A 1 841 ? 24.086 52.481 -33.056 1.00 12.78 ? 841 ASN A N 1 ATOM 6742 C CA . ASN A 1 841 ? 25.047 52.927 -34.044 1.00 12.73 ? 841 ASN A CA 1 ATOM 6743 C C . ASN A 1 841 ? 26.004 54.069 -33.700 1.00 11.18 ? 841 ASN A C 1 ATOM 6744 O O . ASN A 1 841 ? 27.079 54.155 -34.293 1.00 11.90 ? 841 ASN A O 1 ATOM 6745 C CB . ASN A 1 841 ? 24.295 53.385 -35.311 1.00 13.58 ? 841 ASN A CB 1 ATOM 6746 C CG . ASN A 1 841 ? 23.539 52.246 -35.985 1.00 14.92 ? 841 ASN A CG 1 ATOM 6747 O OD1 . ASN A 1 841 ? 24.033 51.141 -36.094 1.00 18.37 ? 841 ASN A OD1 1 ATOM 6748 N ND2 . ASN A 1 841 ? 22.327 52.552 -36.445 1.00 19.22 ? 841 ASN A ND2 1 ATOM 6749 N N . THR A 1 842 ? 25.590 54.908 -32.767 1.00 10.97 ? 842 THR A N 1 ATOM 6750 C CA . THR A 1 842 ? 26.332 56.141 -32.504 1.00 10.88 ? 842 THR A CA 1 ATOM 6751 C C . THR A 1 842 ? 26.583 56.308 -31.015 1.00 10.21 ? 842 THR A C 1 ATOM 6752 O O . THR A 1 842 ? 25.724 56.001 -30.203 1.00 11.20 ? 842 THR A O 1 ATOM 6753 C CB . THR A 1 842 ? 25.460 57.342 -32.969 1.00 9.97 ? 842 THR A CB 1 ATOM 6754 O OG1 . THR A 1 842 ? 25.069 57.116 -34.339 1.00 12.76 ? 842 THR A OG1 1 ATOM 6755 C CG2 . THR A 1 842 ? 26.239 58.668 -32.962 1.00 12.54 ? 842 THR A CG2 1 ATOM 6756 N N . ARG A 1 843 ? 27.763 56.867 -30.738 1.00 10.01 ? 843 ARG A N 1 ATOM 6757 C CA . ARG A 1 843 ? 28.125 57.189 -29.336 1.00 9.93 ? 843 ARG A CA 1 ATOM 6758 C C . ARG A 1 843 ? 28.667 58.633 -29.291 1.00 8.91 ? 843 ARG A C 1 ATOM 6759 O O . ARG A 1 843 ? 29.361 59.078 -30.221 1.00 9.83 ? 843 ARG A O 1 ATOM 6760 C CB . ARG A 1 843 ? 29.238 56.268 -28.844 1.00 10.70 ? 843 ARG A CB 1 ATOM 6761 C CG . ARG A 1 843 ? 29.587 56.545 -27.318 1.00 9.69 ? 843 ARG A CG 1 ATOM 6762 C CD . ARG A 1 843 ? 30.777 55.693 -26.928 1.00 10.07 ? 843 ARG A CD 1 ATOM 6763 N NE . ARG A 1 843 ? 30.413 54.295 -26.655 1.00 9.67 ? 843 ARG A NE 1 ATOM 6764 C CZ . ARG A 1 843 ? 31.236 53.469 -26.050 1.00 10.06 ? 843 ARG A CZ 1 ATOM 6765 N NH1 . ARG A 1 843 ? 32.459 53.843 -25.695 1.00 9.66 ? 843 ARG A NH1 1 ATOM 6766 N NH2 . ARG A 1 843 ? 30.740 52.287 -25.667 1.00 11.03 ? 843 ARG A NH2 1 ATOM 6767 N N . LEU A 1 844 ? 28.293 59.316 -28.227 1.00 8.68 ? 844 LEU A N 1 ATOM 6768 C CA . LEU A 1 844 ? 28.881 60.671 -27.968 1.00 8.63 ? 844 LEU A CA 1 ATOM 6769 C C . LEU A 1 844 ? 29.536 60.540 -26.580 1.00 8.35 ? 844 LEU A C 1 ATOM 6770 O O . LEU A 1 844 ? 28.830 60.249 -25.590 1.00 8.66 ? 844 LEU A O 1 ATOM 6771 C CB . LEU A 1 844 ? 27.813 61.767 -27.932 1.00 9.72 ? 844 LEU A CB 1 ATOM 6772 C CG . LEU A 1 844 ? 28.477 63.167 -27.802 1.00 10.51 ? 844 LEU A CG 1 ATOM 6773 C CD1 . LEU A 1 844 ? 29.350 63.519 -28.984 1.00 12.09 ? 844 LEU A CD1 1 ATOM 6774 C CD2 . LEU A 1 844 ? 27.361 64.193 -27.654 1.00 13.09 ? 844 LEU A CD2 1 ATOM 6775 N N . THR A 1 845 ? 30.844 60.830 -26.559 1.00 8.54 ? 845 THR A N 1 ATOM 6776 C CA . THR A 1 845 ? 31.602 60.791 -25.271 1.00 8.10 ? 845 THR A CA 1 ATOM 6777 C C . THR A 1 845 ? 32.151 62.204 -24.994 1.00 8.03 ? 845 THR A C 1 ATOM 6778 O O . THR A 1 845 ? 32.749 62.834 -25.873 1.00 8.71 ? 845 THR A O 1 ATOM 6779 C CB . THR A 1 845 ? 32.819 59.867 -25.344 1.00 7.88 ? 845 THR A CB 1 ATOM 6780 O OG1 . THR A 1 845 ? 32.365 58.549 -25.755 1.00 9.28 ? 845 THR A OG1 1 ATOM 6781 C CG2 . THR A 1 845 ? 33.467 59.671 -23.962 1.00 9.20 ? 845 THR A CG2 1 ATOM 6782 N N . LEU A 1 846 ? 31.972 62.642 -23.756 1.00 8.47 ? 846 LEU A N 1 ATOM 6783 C CA . LEU A 1 846 ? 32.482 63.928 -23.280 1.00 8.28 ? 846 LEU A CA 1 ATOM 6784 C C . LEU A 1 846 ? 33.529 63.605 -22.222 1.00 7.09 ? 846 LEU A C 1 ATOM 6785 O O . LEU A 1 846 ? 33.177 63.024 -21.178 1.00 7.43 ? 846 LEU A O 1 ATOM 6786 C CB . LEU A 1 846 ? 31.356 64.794 -22.689 1.00 9.58 ? 846 LEU A CB 1 ATOM 6787 C CG . LEU A 1 846 ? 31.795 66.191 -22.195 1.00 10.58 ? 846 LEU A CG 1 ATOM 6788 C CD1 . LEU A 1 846 ? 32.237 67.061 -23.418 1.00 10.14 ? 846 LEU A CD1 1 ATOM 6789 C CD2 . LEU A 1 846 ? 30.687 66.896 -21.410 1.00 13.20 ? 846 LEU A CD2 1 ATOM 6790 N N . LEU A 1 847 ? 34.795 63.906 -22.507 1.00 7.81 ? 847 LEU A N 1 ATOM 6791 C CA . LEU A 1 847 ? 35.890 63.681 -21.520 1.00 6.36 ? 847 LEU A CA 1 ATOM 6792 C C . LEU A 1 847 ? 36.140 65.006 -20.809 1.00 7.29 ? 847 LEU A C 1 ATOM 6793 O O . LEU A 1 847 ? 36.004 66.098 -21.410 1.00 7.55 ? 847 LEU A O 1 ATOM 6794 C CB . LEU A 1 847 ? 37.144 63.223 -22.223 1.00 7.44 ? 847 LEU A CB 1 ATOM 6795 C CG . LEU A 1 847 ? 37.169 61.859 -22.926 1.00 6.97 ? 847 LEU A CG 1 ATOM 6796 C CD1 . LEU A 1 847 ? 36.510 60.768 -22.037 1.00 8.50 ? 847 LEU A CD1 1 ATOM 6797 C CD2 . LEU A 1 847 ? 36.455 61.980 -24.272 1.00 8.31 ? 847 LEU A CD2 1 ATOM 6798 N N . THR A 1 848 ? 36.516 64.911 -19.539 1.00 6.51 ? 848 THR A N 1 ATOM 6799 C CA . THR A 1 848 ? 36.795 66.126 -18.755 1.00 6.80 ? 848 THR A CA 1 ATOM 6800 C C . THR A 1 848 ? 38.220 66.220 -18.194 1.00 7.22 ? 848 THR A C 1 ATOM 6801 O O A THR A 1 848 ? 38.955 65.217 -18.002 0.50 6.51 ? 848 THR A O 1 ATOM 6802 O O B THR A 1 848 ? 38.676 65.210 -17.679 0.50 8.80 ? 848 THR A O 1 ATOM 6803 C CB A THR A 1 848 ? 35.895 66.313 -17.523 0.50 7.10 ? 848 THR A CB 1 ATOM 6804 C CB B THR A 1 848 ? 35.647 66.173 -17.627 0.50 8.97 ? 848 THR A CB 1 ATOM 6805 O OG1 A THR A 1 848 ? 36.227 65.322 -16.539 0.50 4.25 ? 848 THR A OG1 1 ATOM 6806 O OG1 B THR A 1 848 ? 34.379 65.765 -18.128 0.50 13.05 ? 848 THR A OG1 1 ATOM 6807 C CG2 A THR A 1 848 ? 34.476 66.196 -17.818 0.50 8.59 ? 848 THR A CG2 1 ATOM 6808 C CG2 B THR A 1 848 ? 35.573 67.529 -17.049 0.50 9.02 ? 848 THR A CG2 1 ATOM 6809 N N . GLY A 1 849 ? 38.588 67.465 -17.942 1.00 6.71 ? 849 GLY A N 1 ATOM 6810 C CA . GLY A 1 849 ? 39.864 67.710 -17.287 1.00 6.77 ? 849 GLY A CA 1 ATOM 6811 C C . GLY A 1 849 ? 39.680 68.071 -15.846 1.00 5.71 ? 849 GLY A C 1 ATOM 6812 O O . GLY A 1 849 ? 40.635 68.515 -15.208 1.00 6.75 ? 849 GLY A O 1 ATOM 6813 N N . GLN A 1 850 ? 38.497 67.855 -15.285 1.00 5.94 ? 850 GLN A N 1 ATOM 6814 C CA . GLN A 1 850 ? 38.212 68.196 -13.898 1.00 5.53 ? 850 GLN A CA 1 ATOM 6815 C C . GLN A 1 850 ? 36.950 67.448 -13.523 1.00 6.42 ? 850 GLN A C 1 ATOM 6816 O O . GLN A 1 850 ? 36.053 67.216 -14.369 1.00 6.74 ? 850 GLN A O 1 ATOM 6817 C CB . GLN A 1 850 ? 37.986 69.742 -13.775 1.00 7.03 ? 850 GLN A CB 1 ATOM 6818 C CG . GLN A 1 850 ? 36.830 70.301 -14.687 1.00 7.11 ? 850 GLN A CG 1 ATOM 6819 C CD . GLN A 1 850 ? 37.190 70.401 -16.144 1.00 6.96 ? 850 GLN A CD 1 ATOM 6820 O OE1 . GLN A 1 850 ? 38.300 70.802 -16.520 1.00 7.77 ? 850 GLN A OE1 1 ATOM 6821 N NE2 . GLN A 1 850 ? 36.232 70.072 -17.016 1.00 7.42 ? 850 GLN A NE2 1 ATOM 6822 N N . PRO A 1 851 ? 36.813 67.047 -12.260 1.00 5.52 ? 851 PRO A N 1 ATOM 6823 C CA . PRO A 1 851 ? 35.577 66.336 -11.867 1.00 6.22 ? 851 PRO A CA 1 ATOM 6824 C C . PRO A 1 851 ? 34.468 67.338 -11.682 1.00 6.12 ? 851 PRO A C 1 ATOM 6825 O O . PRO A 1 851 ? 34.658 68.375 -11.023 1.00 6.69 ? 851 PRO A O 1 ATOM 6826 C CB . PRO A 1 851 ? 35.948 65.659 -10.508 1.00 6.15 ? 851 PRO A CB 1 ATOM 6827 C CG . PRO A 1 851 ? 37.108 66.611 -9.954 1.00 6.14 ? 851 PRO A CG 1 ATOM 6828 C CD . PRO A 1 851 ? 37.861 67.048 -11.207 1.00 5.25 ? 851 PRO A CD 1 ATOM 6829 N N . LEU A 1 852 ? 33.279 67.007 -12.249 1.00 6.74 ? 852 LEU A N 1 ATOM 6830 C CA . LEU A 1 852 ? 32.088 67.866 -12.123 1.00 7.24 ? 852 LEU A CA 1 ATOM 6831 C C . LEU A 1 852 ? 30.885 66.940 -12.020 1.00 8.19 ? 852 LEU A C 1 ATOM 6832 O O . LEU A 1 852 ? 31.019 65.766 -12.294 1.00 11.02 ? 852 LEU A O 1 ATOM 6833 C CB . LEU A 1 852 ? 31.956 68.748 -13.362 1.00 8.01 ? 852 LEU A CB 1 ATOM 6834 C CG . LEU A 1 852 ? 33.119 69.779 -13.502 1.00 6.92 ? 852 LEU A CG 1 ATOM 6835 C CD1 . LEU A 1 852 ? 33.043 70.350 -14.974 1.00 9.26 ? 852 LEU A CD1 1 ATOM 6836 C CD2 . LEU A 1 852 ? 33.035 70.923 -12.506 1.00 8.00 ? 852 LEU A CD2 1 ATOM 6837 N N . GLY A 1 853 ? 29.728 67.472 -11.684 1.00 6.82 ? 853 GLY A N 1 ATOM 6838 C CA . GLY A 1 853 ? 28.539 66.616 -11.638 1.00 7.78 ? 853 GLY A CA 1 ATOM 6839 C C . GLY A 1 853 ? 27.799 66.608 -12.967 1.00 6.81 ? 853 GLY A C 1 ATOM 6840 O O . GLY A 1 853 ? 27.833 67.594 -13.725 1.00 7.32 ? 853 GLY A O 1 ATOM 6841 N N . GLY A 1 854 ? 27.092 65.523 -13.262 1.00 6.71 ? 854 GLY A N 1 ATOM 6842 C CA . GLY A 1 854 ? 26.385 65.493 -14.533 1.00 8.05 ? 854 GLY A CA 1 ATOM 6843 C C . GLY A 1 854 ? 25.354 64.385 -14.627 1.00 7.11 ? 854 GLY A C 1 ATOM 6844 O O . GLY A 1 854 ? 25.163 63.573 -13.703 1.00 7.69 ? 854 GLY A O 1 ATOM 6845 N N . SER A 1 855 ? 24.669 64.367 -15.775 1.00 7.50 ? 855 SER A N 1 ATOM 6846 C CA . SER A 1 855 ? 23.600 63.372 -15.938 1.00 8.34 ? 855 SER A CA 1 ATOM 6847 C C . SER A 1 855 ? 23.222 63.330 -17.390 1.00 8.14 ? 855 SER A C 1 ATOM 6848 O O . SER A 1 855 ? 23.788 64.019 -18.233 1.00 8.99 ? 855 SER A O 1 ATOM 6849 C CB . SER A 1 855 ? 22.364 63.865 -15.180 1.00 9.16 ? 855 SER A CB 1 ATOM 6850 O OG . SER A 1 855 ? 21.376 62.827 -15.128 1.00 9.70 ? 855 SER A OG 1 ATOM 6851 N N . SER A 1 856 ? 22.230 62.467 -17.670 1.00 8.35 ? 856 SER A N 1 ATOM 6852 C CA . SER A 1 856 ? 21.538 62.436 -18.991 1.00 8.59 ? 856 SER A CA 1 ATOM 6853 C C . SER A 1 856 ? 20.075 62.442 -18.546 1.00 9.33 ? 856 SER A C 1 ATOM 6854 O O . SER A 1 856 ? 19.541 61.387 -18.158 1.00 10.09 ? 856 SER A O 1 ATOM 6855 C CB . SER A 1 856 ? 21.864 61.161 -19.707 1.00 8.39 ? 856 SER A CB 1 ATOM 6856 O OG . SER A 1 856 ? 21.057 61.092 -20.910 1.00 10.26 ? 856 SER A OG 1 ATOM 6857 N N . LEU A 1 857 ? 19.402 63.603 -18.598 1.00 9.58 ? 857 LEU A N 1 ATOM 6858 C CA . LEU A 1 857 ? 18.027 63.732 -18.078 1.00 10.07 ? 857 LEU A CA 1 ATOM 6859 C C . LEU A 1 857 ? 16.944 63.393 -19.093 1.00 10.21 ? 857 LEU A C 1 ATOM 6860 O O . LEU A 1 857 ? 15.769 63.329 -18.735 1.00 11.52 ? 857 LEU A O 1 ATOM 6861 C CB . LEU A 1 857 ? 17.831 65.148 -17.467 1.00 10.68 ? 857 LEU A CB 1 ATOM 6862 C CG . LEU A 1 857 ? 18.682 65.343 -16.222 1.00 10.70 ? 857 LEU A CG 1 ATOM 6863 C CD1 . LEU A 1 857 ? 18.511 66.799 -15.728 1.00 12.67 ? 857 LEU A CD1 1 ATOM 6864 C CD2 . LEU A 1 857 ? 18.283 64.347 -15.117 1.00 11.57 ? 857 LEU A CD2 1 ATOM 6865 N N . ALA A 1 858 ? 17.371 63.195 -20.295 1.00 9.52 ? 858 ALA A N 1 ATOM 6866 C CA . ALA A 1 858 ? 16.478 62.745 -21.396 1.00 10.07 ? 858 ALA A CA 1 ATOM 6867 C C . ALA A 1 858 ? 17.297 62.039 -22.463 1.00 10.89 ? 858 ALA A C 1 ATOM 6868 O O . ALA A 1 858 ? 18.505 62.284 -22.622 1.00 10.52 ? 858 ALA A O 1 ATOM 6869 C CB . ALA A 1 858 ? 15.714 63.957 -22.020 1.00 11.89 ? 858 ALA A CB 1 ATOM 6870 N N . SER A 1 859 ? 16.674 61.143 -23.227 1.00 11.19 ? 859 SER A N 1 ATOM 6871 C CA . SER A 1 859 ? 17.330 60.408 -24.272 1.00 10.38 ? 859 SER A CA 1 ATOM 6872 C C . SER A 1 859 ? 18.055 61.370 -25.202 1.00 9.52 ? 859 SER A C 1 ATOM 6873 O O . SER A 1 859 ? 17.498 62.418 -25.574 1.00 12.27 ? 859 SER A O 1 ATOM 6874 C CB . SER A 1 859 ? 16.233 59.586 -25.044 1.00 12.20 ? 859 SER A CB 1 ATOM 6875 O OG . SER A 1 859 ? 16.794 58.823 -26.024 1.00 12.64 ? 859 SER A OG 1 ATOM 6876 N N . GLY A 1 860 ? 19.270 61.026 -25.581 1.00 10.51 ? 860 GLY A N 1 ATOM 6877 C CA . GLY A 1 860 ? 20.044 61.867 -26.480 1.00 10.79 ? 860 GLY A CA 1 ATOM 6878 C C . GLY A 1 860 ? 20.795 63.013 -25.774 1.00 9.58 ? 860 GLY A C 1 ATOM 6879 O O . GLY A 1 860 ? 21.565 63.674 -26.481 1.00 10.09 ? 860 GLY A O 1 ATOM 6880 N N . GLU A 1 861 ? 20.624 63.207 -24.466 1.00 9.85 ? 861 GLU A N 1 ATOM 6881 C CA . GLU A 1 861 ? 21.286 64.314 -23.791 1.00 9.81 ? 861 GLU A CA 1 ATOM 6882 C C . GLU A 1 861 ? 22.433 63.915 -22.883 1.00 9.70 ? 861 GLU A C 1 ATOM 6883 O O . GLU A 1 861 ? 22.491 62.806 -22.341 1.00 10.93 ? 861 GLU A O 1 ATOM 6884 C CB . GLU A 1 861 ? 20.339 65.085 -22.886 1.00 11.09 ? 861 GLU A CB 1 ATOM 6885 C CG . GLU A 1 861 ? 19.171 65.735 -23.608 1.00 12.82 ? 861 GLU A CG 1 ATOM 6886 C CD . GLU A 1 861 ? 18.289 66.568 -22.701 1.00 13.60 ? 861 GLU A CD 1 ATOM 6887 O OE1 . GLU A 1 861 ? 18.445 66.628 -21.467 1.00 13.68 ? 861 GLU A OE1 1 ATOM 6888 O OE2 . GLU A 1 861 ? 17.312 67.196 -23.261 1.00 16.31 ? 861 GLU A OE2 1 ATOM 6889 N N . LEU A 1 862 ? 23.356 64.845 -22.784 1.00 9.48 ? 862 LEU A N 1 ATOM 6890 C CA . LEU A 1 862 ? 24.422 64.774 -21.744 1.00 9.22 ? 862 LEU A CA 1 ATOM 6891 C C . LEU A 1 862 ? 24.445 66.138 -21.101 1.00 8.16 ? 862 LEU A C 1 ATOM 6892 O O . LEU A 1 862 ? 24.258 67.152 -21.793 1.00 8.81 ? 862 LEU A O 1 ATOM 6893 C CB . LEU A 1 862 ? 25.836 64.510 -22.374 1.00 9.57 ? 862 LEU A CB 1 ATOM 6894 C CG . LEU A 1 862 ? 26.220 63.139 -23.024 1.00 10.18 ? 862 LEU A CG 1 ATOM 6895 C CD1 . LEU A 1 862 ? 27.515 63.164 -23.773 1.00 10.20 ? 862 LEU A CD1 1 ATOM 6896 C CD2 . LEU A 1 862 ? 26.173 62.064 -21.907 1.00 11.05 ? 862 LEU A CD2 1 ATOM 6897 N N . GLU A 1 863 ? 24.698 66.220 -19.804 1.00 7.95 ? 863 GLU A N 1 ATOM 6898 C CA . GLU A 1 863 ? 24.871 67.552 -19.218 1.00 8.51 ? 863 GLU A CA 1 ATOM 6899 C C . GLU A 1 863 ? 25.854 67.482 -18.078 1.00 8.02 ? 863 GLU A C 1 ATOM 6900 O O . GLU A 1 863 ? 25.978 66.452 -17.412 1.00 8.15 ? 863 GLU A O 1 ATOM 6901 C CB . GLU A 1 863 ? 23.558 68.226 -18.790 1.00 9.00 ? 863 GLU A CB 1 ATOM 6902 C CG . GLU A 1 863 ? 22.958 67.644 -17.545 1.00 9.95 ? 863 GLU A CG 1 ATOM 6903 C CD . GLU A 1 863 ? 21.690 68.372 -17.127 1.00 8.63 ? 863 GLU A CD 1 ATOM 6904 O OE1 . GLU A 1 863 ? 20.789 68.385 -18.018 1.00 11.19 ? 863 GLU A OE1 1 ATOM 6905 O OE2 . GLU A 1 863 ? 21.558 68.879 -16.004 1.00 10.01 ? 863 GLU A OE2 1 ATOM 6906 N N . ILE A 1 864 ? 26.603 68.570 -17.917 1.00 8.20 ? 864 ILE A N 1 ATOM 6907 C CA . ILE A 1 864 ? 27.638 68.637 -16.859 1.00 7.74 ? 864 ILE A CA 1 ATOM 6908 C C . ILE A 1 864 ? 27.625 70.029 -16.235 1.00 7.38 ? 864 ILE A C 1 ATOM 6909 O O . ILE A 1 864 ? 27.644 71.049 -16.975 1.00 7.94 ? 864 ILE A O 1 ATOM 6910 C CB . ILE A 1 864 ? 28.985 68.225 -17.484 1.00 9.44 ? 864 ILE A CB 1 ATOM 6911 C CG1 . ILE A 1 864 ? 30.056 68.182 -16.384 1.00 10.85 ? 864 ILE A CG1 1 ATOM 6912 C CG2 . ILE A 1 864 ? 29.368 69.096 -18.664 1.00 10.69 ? 864 ILE A CG2 1 ATOM 6913 C CD1 . ILE A 1 864 ? 31.172 67.134 -16.850 1.00 11.80 ? 864 ILE A CD1 1 ATOM 6914 N N . MET A 1 865 ? 27.567 70.070 -14.917 1.00 7.08 ? 865 MET A N 1 ATOM 6915 C CA . MET A 1 865 ? 27.528 71.345 -14.203 1.00 7.31 ? 865 MET A CA 1 ATOM 6916 C C . MET A 1 865 ? 28.894 72.049 -14.247 1.00 8.04 ? 865 MET A C 1 ATOM 6917 O O . MET A 1 865 ? 29.935 71.435 -14.080 1.00 8.52 ? 865 MET A O 1 ATOM 6918 C CB . MET A 1 865 ? 27.079 71.117 -12.748 1.00 7.38 ? 865 MET A CB 1 ATOM 6919 C CG . MET A 1 865 ? 26.476 72.381 -12.081 1.00 7.60 ? 865 MET A CG 1 ATOM 6920 S SD . MET A 1 865 ? 24.830 72.788 -12.813 1.00 9.85 ? 865 MET A SD 1 ATOM 6921 C CE . MET A 1 865 ? 23.848 71.539 -11.893 1.00 9.81 ? 865 MET A CE 1 ATOM 6922 N N . GLN A 1 866 ? 28.860 73.367 -14.453 1.00 8.28 ? 866 GLN A N 1 ATOM 6923 C CA . GLN A 1 866 ? 30.074 74.192 -14.574 1.00 7.75 ? 866 GLN A CA 1 ATOM 6924 C C . GLN A 1 866 ? 30.460 74.895 -13.268 1.00 8.21 ? 866 GLN A C 1 ATOM 6925 O O . GLN A 1 866 ? 31.655 74.918 -12.916 1.00 8.99 ? 866 GLN A O 1 ATOM 6926 C CB . GLN A 1 866 ? 29.891 75.236 -15.679 1.00 8.41 ? 866 GLN A CB 1 ATOM 6927 C CG . GLN A 1 866 ? 29.551 74.618 -17.029 1.00 9.00 ? 866 GLN A CG 1 ATOM 6928 C CD . GLN A 1 866 ? 30.589 73.651 -17.466 1.00 9.07 ? 866 GLN A CD 1 ATOM 6929 O OE1 . GLN A 1 866 ? 31.735 74.007 -17.806 1.00 8.98 ? 866 GLN A OE1 1 ATOM 6930 N NE2 . GLN A 1 866 ? 30.219 72.394 -17.457 1.00 9.32 ? 866 GLN A NE2 1 ATOM 6931 N N . ASP A 1 867 ? 29.492 75.503 -12.575 1.00 8.15 ? 867 ASP A N 1 ATOM 6932 C CA . ASP A 1 867 ? 29.746 76.140 -11.268 1.00 8.53 ? 867 ASP A CA 1 ATOM 6933 C C . ASP A 1 867 ? 28.417 76.367 -10.607 1.00 7.81 ? 867 ASP A C 1 ATOM 6934 O O . ASP A 1 867 ? 27.352 76.230 -11.286 1.00 8.43 ? 867 ASP A O 1 ATOM 6935 C CB . ASP A 1 867 ? 30.556 77.452 -11.416 1.00 8.69 ? 867 ASP A CB 1 ATOM 6936 C CG . ASP A 1 867 ? 31.270 77.849 -10.121 1.00 8.42 ? 867 ASP A CG 1 ATOM 6937 O OD1 . ASP A 1 867 ? 31.120 77.186 -9.091 1.00 8.77 ? 867 ASP A OD1 1 ATOM 6938 O OD2 . ASP A 1 867 ? 31.972 78.875 -10.169 1.00 9.25 ? 867 ASP A OD2 1 ATOM 6939 N N . ARG A 1 868 ? 28.458 76.619 -9.321 1.00 8.23 ? 868 ARG A N 1 ATOM 6940 C CA . ARG A 1 868 ? 27.242 76.855 -8.551 1.00 8.22 ? 868 ARG A CA 1 ATOM 6941 C C . ARG A 1 868 ? 27.570 77.893 -7.477 1.00 8.50 ? 868 ARG A C 1 ATOM 6942 O O . ARG A 1 868 ? 28.628 77.830 -6.827 1.00 8.72 ? 868 ARG A O 1 ATOM 6943 C CB . ARG A 1 868 ? 26.700 75.527 -7.951 1.00 8.64 ? 868 ARG A CB 1 ATOM 6944 C CG . ARG A 1 868 ? 27.743 74.783 -7.095 1.00 9.24 ? 868 ARG A CG 1 ATOM 6945 C CD . ARG A 1 868 ? 27.498 73.266 -7.097 1.00 8.05 ? 868 ARG A CD 1 ATOM 6946 N NE . ARG A 1 868 ? 26.114 72.932 -6.690 1.00 7.85 ? 868 ARG A NE 1 ATOM 6947 C CZ . ARG A 1 868 ? 25.768 72.623 -5.455 1.00 7.82 ? 868 ARG A CZ 1 ATOM 6948 N NH1 . ARG A 1 868 ? 26.672 72.524 -4.460 1.00 8.52 ? 868 ARG A NH1 1 ATOM 6949 N NH2 . ARG A 1 868 ? 24.450 72.497 -5.195 1.00 9.18 ? 868 ARG A NH2 1 ATOM 6950 N N . ARG A 1 869 ? 26.644 78.838 -7.305 1.00 9.35 ? 869 ARG A N 1 ATOM 6951 C CA . ARG A 1 869 ? 26.841 79.929 -6.308 1.00 10.06 ? 869 ARG A CA 1 ATOM 6952 C C . ARG A 1 869 ? 25.563 79.909 -5.507 1.00 9.81 ? 869 ARG A C 1 ATOM 6953 O O . ARG A 1 869 ? 24.495 80.098 -6.059 1.00 10.57 ? 869 ARG A O 1 ATOM 6954 C CB . ARG A 1 869 ? 27.042 81.281 -7.021 1.00 10.95 ? 869 ARG A CB 1 ATOM 6955 C CG . ARG A 1 869 ? 27.223 82.409 -6.033 1.00 11.27 ? 869 ARG A CG 1 ATOM 6956 C CD . ARG A 1 869 ? 27.524 83.697 -6.820 1.00 14.53 ? 869 ARG A CD 1 ATOM 6957 N NE . ARG A 1 869 ? 27.719 84.860 -5.930 1.00 16.33 ? 869 ARG A NE 1 ATOM 6958 C CZ . ARG A 1 869 ? 28.862 85.185 -5.361 1.00 15.63 ? 869 ARG A CZ 1 ATOM 6959 N NH1 . ARG A 1 869 ? 29.958 84.477 -5.548 1.00 16.03 ? 869 ARG A NH1 1 ATOM 6960 N NH2 . ARG A 1 869 ? 28.899 86.276 -4.578 1.00 17.71 ? 869 ARG A NH2 1 ATOM 6961 N N . LEU A 1 870 ? 25.709 79.631 -4.229 1.00 11.44 ? 870 LEU A N 1 ATOM 6962 C CA . LEU A 1 870 ? 24.568 79.369 -3.304 1.00 11.48 ? 870 LEU A CA 1 ATOM 6963 C C . LEU A 1 870 ? 24.636 80.205 -2.058 1.00 12.08 ? 870 LEU A C 1 ATOM 6964 O O . LEU A 1 870 ? 25.615 80.196 -1.327 1.00 11.67 ? 870 LEU A O 1 ATOM 6965 C CB . LEU A 1 870 ? 24.629 77.882 -2.943 1.00 12.60 ? 870 LEU A CB 1 ATOM 6966 C CG . LEU A 1 870 ? 24.621 77.027 -4.210 1.00 14.49 ? 870 LEU A CG 1 ATOM 6967 C CD1 . LEU A 1 870 ? 25.076 75.681 -3.882 1.00 16.72 ? 870 LEU A CD1 1 ATOM 6968 C CD2 . LEU A 1 870 ? 23.287 77.006 -4.908 1.00 13.78 ? 870 LEU A CD2 1 ATOM 6969 N N . ALA A 1 871 ? 23.528 80.898 -1.773 1.00 12.77 ? 871 ALA A N 1 ATOM 6970 C CA . ALA A 1 871 ? 23.537 81.770 -0.623 1.00 14.24 ? 871 ALA A CA 1 ATOM 6971 C C . ALA A 1 871 ? 23.347 81.070 0.735 1.00 15.28 ? 871 ALA A C 1 ATOM 6972 O O . ALA A 1 871 ? 23.765 81.568 1.785 1.00 17.06 ? 871 ALA A O 1 ATOM 6973 C CB . ALA A 1 871 ? 22.408 82.824 -0.808 1.00 15.81 ? 871 ALA A CB 1 ATOM 6974 N N . SER A 1 872 ? 22.754 79.889 0.691 1.00 14.70 ? 872 SER A N 1 ATOM 6975 C CA . SER A 1 872 ? 22.413 79.208 1.919 1.00 15.42 ? 872 SER A CA 1 ATOM 6976 C C . SER A 1 872 ? 23.271 78.061 2.323 1.00 14.20 ? 872 SER A C 1 ATOM 6977 O O . SER A 1 872 ? 23.908 77.447 1.466 1.00 14.16 ? 872 SER A O 1 ATOM 6978 C CB . SER A 1 872 ? 20.977 78.690 1.793 1.00 18.03 ? 872 SER A CB 1 ATOM 6979 O OG . SER A 1 872 ? 20.099 79.780 1.519 1.00 21.42 ? 872 SER A OG 1 ATOM 6980 N N . ASP A 1 873 ? 23.340 77.839 3.630 1.00 13.89 ? 873 ASP A N 1 ATOM 6981 C CA . ASP A 1 873 ? 23.964 76.654 4.243 1.00 13.49 ? 873 ASP A CA 1 ATOM 6982 C C . ASP A 1 873 ? 22.945 75.508 4.069 1.00 13.81 ? 873 ASP A C 1 ATOM 6983 O O . ASP A 1 873 ? 21.740 75.729 4.117 1.00 14.25 ? 873 ASP A O 1 ATOM 6984 C CB . ASP A 1 873 ? 24.200 76.868 5.727 1.00 13.30 ? 873 ASP A CB 1 ATOM 6985 C CG . ASP A 1 873 ? 24.668 75.610 6.401 1.00 13.11 ? 873 ASP A CG 1 ATOM 6986 O OD1 . ASP A 1 873 ? 25.774 75.133 6.015 1.00 14.56 ? 873 ASP A OD1 1 ATOM 6987 O OD2 . ASP A 1 873 ? 23.978 75.068 7.291 1.00 15.28 ? 873 ASP A OD2 1 ATOM 6988 N N . ASP A 1 874 ? 23.438 74.281 3.876 1.00 12.13 ? 874 ASP A N 1 ATOM 6989 C CA . ASP A 1 874 ? 22.546 73.149 3.675 1.00 10.71 ? 874 ASP A CA 1 ATOM 6990 C C . ASP A 1 874 ? 22.488 72.170 4.839 1.00 10.56 ? 874 ASP A C 1 ATOM 6991 O O . ASP A 1 874 ? 22.275 70.965 4.663 1.00 11.70 ? 874 ASP A O 1 ATOM 6992 C CB . ASP A 1 874 ? 22.866 72.436 2.347 1.00 10.92 ? 874 ASP A CB 1 ATOM 6993 C CG . ASP A 1 874 ? 24.352 72.047 2.206 1.00 9.26 ? 874 ASP A CG 1 ATOM 6994 O OD1 . ASP A 1 874 ? 25.157 72.296 3.124 1.00 11.46 ? 874 ASP A OD1 1 ATOM 6995 O OD2 . ASP A 1 874 ? 24.622 71.482 1.142 1.00 10.04 ? 874 ASP A OD2 1 ATOM 6996 N N . GLU A 1 875 ? 22.755 72.686 6.026 1.00 11.52 ? 875 GLU A N 1 ATOM 6997 C CA . GLU A 1 875 ? 22.503 71.898 7.252 1.00 12.74 ? 875 GLU A CA 1 ATOM 6998 C C . GLU A 1 875 ? 23.292 70.644 7.479 1.00 12.83 ? 875 GLU A C 1 ATOM 6999 O O . GLU A 1 875 ? 22.882 69.732 8.191 1.00 13.10 ? 875 GLU A O 1 ATOM 7000 C CB . GLU A 1 875 ? 20.986 71.573 7.372 1.00 16.29 ? 875 GLU A CB 1 ATOM 7001 C CG . GLU A 1 875 ? 20.112 72.858 7.282 1.00 21.86 ? 875 GLU A CG 1 ATOM 7002 C CD . GLU A 1 875 ? 18.684 72.702 7.844 1.00 25.97 ? 875 GLU A CD 1 ATOM 7003 O OE1 . GLU A 1 875 ? 18.528 72.312 9.014 1.00 30.94 ? 875 GLU A OE1 1 ATOM 7004 O OE2 . GLU A 1 875 ? 17.716 72.979 7.125 1.00 29.26 ? 875 GLU A OE2 1 ATOM 7005 N N . ARG A 1 876 ? 24.479 70.610 6.883 1.00 11.42 ? 876 ARG A N 1 ATOM 7006 C CA . ARG A 1 876 ? 25.389 69.463 7.053 1.00 11.35 ? 876 ARG A CA 1 ATOM 7007 C C . ARG A 1 876 ? 26.656 69.839 7.841 1.00 11.69 ? 876 ARG A C 1 ATOM 7008 O O . ARG A 1 876 ? 27.632 69.080 7.877 1.00 11.96 ? 876 ARG A O 1 ATOM 7009 C CB . ARG A 1 876 ? 25.718 68.835 5.672 1.00 10.39 ? 876 ARG A CB 1 ATOM 7010 C CG . ARG A 1 876 ? 24.468 68.286 4.920 1.00 10.23 ? 876 ARG A CG 1 ATOM 7011 C CD . ARG A 1 876 ? 23.685 67.335 5.818 1.00 10.73 ? 876 ARG A CD 1 ATOM 7012 N NE . ARG A 1 876 ? 22.591 66.617 5.147 1.00 9.91 ? 876 ARG A NE 1 ATOM 7013 C CZ . ARG A 1 876 ? 21.397 67.156 4.877 1.00 9.79 ? 876 ARG A CZ 1 ATOM 7014 N NH1 . ARG A 1 876 ? 21.159 68.453 5.146 1.00 10.31 ? 876 ARG A NH1 1 ATOM 7015 N NH2 . ARG A 1 876 ? 20.415 66.356 4.436 1.00 10.29 ? 876 ARG A NH2 1 ATOM 7016 N N . GLY A 1 877 ? 26.652 71.030 8.441 1.00 11.78 ? 877 GLY A N 1 ATOM 7017 C CA . GLY A 1 877 ? 27.756 71.454 9.299 1.00 11.33 ? 877 GLY A CA 1 ATOM 7018 C C . GLY A 1 877 ? 28.700 72.516 8.787 1.00 11.23 ? 877 GLY A C 1 ATOM 7019 O O . GLY A 1 877 ? 29.505 73.023 9.562 1.00 12.83 ? 877 GLY A O 1 ATOM 7020 N N . LEU A 1 878 ? 28.627 72.815 7.500 1.00 10.32 ? 878 LEU A N 1 ATOM 7021 C CA . LEU A 1 878 ? 29.567 73.808 6.919 1.00 11.80 ? 878 LEU A CA 1 ATOM 7022 C C . LEU A 1 878 ? 29.330 75.217 7.461 1.00 12.34 ? 878 LEU A C 1 ATOM 7023 O O . LEU A 1 878 ? 30.269 75.949 7.726 1.00 12.07 ? 878 LEU A O 1 ATOM 7024 C CB . LEU A 1 878 ? 29.498 73.781 5.374 1.00 11.42 ? 878 LEU A CB 1 ATOM 7025 C CG . LEU A 1 878 ? 30.243 74.886 4.617 1.00 10.76 ? 878 LEU A CG 1 ATOM 7026 C CD1 . LEU A 1 878 ? 31.737 74.860 5.018 1.00 11.34 ? 878 LEU A CD1 1 ATOM 7027 C CD2 . LEU A 1 878 ? 30.066 74.681 3.100 1.00 11.40 ? 878 LEU A CD2 1 ATOM 7028 N N . GLY A 1 879 ? 28.060 75.572 7.644 1.00 11.35 ? 879 GLY A N 1 ATOM 7029 C CA . GLY A 1 879 ? 27.796 76.877 8.231 1.00 13.05 ? 879 GLY A CA 1 ATOM 7030 C C . GLY A 1 879 ? 28.000 78.078 7.337 1.00 13.50 ? 879 GLY A C 1 ATOM 7031 O O . GLY A 1 879 ? 28.216 79.177 7.837 1.00 15.85 ? 879 GLY A O 1 ATOM 7032 N N . GLN A 1 880 ? 27.954 77.880 6.038 1.00 12.30 ? 880 GLN A N 1 ATOM 7033 C CA . GLN A 1 880 ? 28.013 79.009 5.113 1.00 12.35 ? 880 GLN A CA 1 ATOM 7034 C C . GLN A 1 880 ? 27.489 78.524 3.762 1.00 12.75 ? 880 GLN A C 1 ATOM 7035 O O . GLN A 1 880 ? 27.406 77.318 3.553 1.00 13.32 ? 880 GLN A O 1 ATOM 7036 C CB . GLN A 1 880 ? 29.455 79.547 4.947 1.00 11.46 ? 880 GLN A CB 1 ATOM 7037 C CG . GLN A 1 880 ? 30.499 78.510 4.436 1.00 12.70 ? 880 GLN A CG 1 ATOM 7038 C CD . GLN A 1 880 ? 31.745 79.169 3.848 1.00 10.91 ? 880 GLN A CD 1 ATOM 7039 O OE1 . GLN A 1 880 ? 31.801 79.442 2.634 1.00 15.43 ? 880 GLN A OE1 1 ATOM 7040 N NE2 . GLN A 1 880 ? 32.697 79.437 4.659 1.00 10.51 ? 880 GLN A NE2 1 ATOM 7041 N N . GLY A 1 881 ? 27.183 79.472 2.877 1.00 13.42 ? 881 GLY A N 1 ATOM 7042 C CA . GLY A 1 881 ? 26.823 79.137 1.497 1.00 14.40 ? 881 GLY A CA 1 ATOM 7043 C C . GLY A 1 881 ? 28.136 79.015 0.692 1.00 13.31 ? 881 GLY A C 1 ATOM 7044 O O . GLY A 1 881 ? 29.239 78.881 1.241 1.00 14.85 ? 881 GLY A O 1 ATOM 7045 N N . VAL A 1 882 ? 27.999 79.008 -0.628 1.00 12.47 ? 882 VAL A N 1 ATOM 7046 C CA . VAL A 1 882 ? 29.162 78.939 -1.518 1.00 10.55 ? 882 VAL A CA 1 ATOM 7047 C C . VAL A 1 882 ? 29.089 80.230 -2.316 1.00 10.60 ? 882 VAL A C 1 ATOM 7048 O O . VAL A 1 882 ? 28.345 80.370 -3.275 1.00 10.93 ? 882 VAL A O 1 ATOM 7049 C CB . VAL A 1 882 ? 29.053 77.708 -2.439 1.00 11.09 ? 882 VAL A CB 1 ATOM 7050 C CG1 . VAL A 1 882 ? 30.194 77.701 -3.469 1.00 11.80 ? 882 VAL A CG1 1 ATOM 7051 C CG2 . VAL A 1 882 ? 29.125 76.427 -1.578 1.00 13.06 ? 882 VAL A CG2 1 ATOM 7052 N N . LEU A 1 883 ? 29.841 81.211 -1.806 1.00 11.80 ? 883 LEU A N 1 ATOM 7053 C CA . LEU A 1 883 ? 29.841 82.559 -2.421 1.00 12.82 ? 883 LEU A CA 1 ATOM 7054 C C . LEU A 1 883 ? 31.245 83.044 -2.734 1.00 13.36 ? 883 LEU A C 1 ATOM 7055 O O . LEU A 1 883 ? 31.464 84.256 -2.923 1.00 16.04 ? 883 LEU A O 1 ATOM 7056 C CB . LEU A 1 883 ? 29.140 83.571 -1.487 1.00 14.15 ? 883 LEU A CB 1 ATOM 7057 C CG . LEU A 1 883 ? 27.674 83.221 -1.150 1.00 13.68 ? 883 LEU A CG 1 ATOM 7058 C CD1 . LEU A 1 883 ? 27.086 84.208 -0.058 1.00 15.19 ? 883 LEU A CD1 1 ATOM 7059 C CD2 . LEU A 1 883 ? 26.834 83.365 -2.419 1.00 15.09 ? 883 LEU A CD2 1 ATOM 7060 N N . ASP A 1 884 ? 32.182 82.126 -2.800 1.00 11.43 ? 884 ASP A N 1 ATOM 7061 C CA . ASP A 1 884 ? 33.581 82.431 -3.043 1.00 11.11 ? 884 ASP A CA 1 ATOM 7062 C C . ASP A 1 884 ? 34.070 81.979 -4.407 1.00 11.24 ? 884 ASP A C 1 ATOM 7063 O O . ASP A 1 884 ? 35.251 81.720 -4.595 1.00 11.56 ? 884 ASP A O 1 ATOM 7064 C CB . ASP A 1 884 ? 34.463 81.819 -1.956 1.00 12.65 ? 884 ASP A CB 1 ATOM 7065 C CG . ASP A 1 884 ? 34.262 80.302 -1.743 1.00 12.82 ? 884 ASP A CG 1 ATOM 7066 O OD1 . ASP A 1 884 ? 33.456 79.668 -2.453 1.00 12.00 ? 884 ASP A OD1 1 ATOM 7067 O OD2 . ASP A 1 884 ? 34.940 79.801 -0.803 1.00 15.83 ? 884 ASP A OD2 1 ATOM 7068 N N . ASN A 1 885 ? 33.155 81.925 -5.359 1.00 10.00 ? 885 ASN A N 1 ATOM 7069 C CA . ASN A 1 885 ? 33.463 81.530 -6.717 1.00 10.84 ? 885 ASN A CA 1 ATOM 7070 C C . ASN A 1 885 ? 34.529 82.398 -7.348 1.00 11.49 ? 885 ASN A C 1 ATOM 7071 O O . ASN A 1 885 ? 34.636 83.589 -7.027 1.00 12.05 ? 885 ASN A O 1 ATOM 7072 C CB . ASN A 1 885 ? 32.228 81.654 -7.587 1.00 10.93 ? 885 ASN A CB 1 ATOM 7073 C CG . ASN A 1 885 ? 31.039 80.913 -7.019 1.00 10.60 ? 885 ASN A CG 1 ATOM 7074 O OD1 . ASN A 1 885 ? 30.710 79.786 -7.464 1.00 12.71 ? 885 ASN A OD1 1 ATOM 7075 N ND2 . ASN A 1 885 ? 30.377 81.510 -6.055 1.00 10.38 ? 885 ASN A ND2 1 ATOM 7076 N N . LYS A 1 886 ? 35.312 81.802 -8.231 1.00 10.23 ? 886 LYS A N 1 ATOM 7077 C CA . LYS A 1 886 ? 36.325 82.530 -8.944 1.00 12.55 ? 886 LYS A CA 1 ATOM 7078 C C . LYS A 1 886 ? 36.406 81.943 -10.348 1.00 11.80 ? 886 LYS A C 1 ATOM 7079 O O . LYS A 1 886 ? 36.025 80.799 -10.588 1.00 11.13 ? 886 LYS A O 1 ATOM 7080 C CB . LYS A 1 886 ? 37.659 82.450 -8.207 1.00 15.34 ? 886 LYS A CB 1 ATOM 7081 C CG . LYS A 1 886 ? 38.193 81.033 -8.014 1.00 17.10 ? 886 LYS A CG 1 ATOM 7082 C CD . LYS A 1 886 ? 39.303 80.923 -6.921 1.00 19.51 ? 886 LYS A CD 1 ATOM 7083 C CE . LYS A 1 886 ? 40.585 81.459 -7.469 1.00 20.13 ? 886 LYS A CE 1 ATOM 7084 N NZ . LYS A 1 886 ? 41.747 81.560 -6.506 1.00 20.97 ? 886 LYS A NZ 1 ATOM 7085 N N . PRO A 1 887 ? 36.871 82.718 -11.317 1.00 9.74 ? 887 PRO A N 1 ATOM 7086 C CA . PRO A 1 887 ? 36.966 82.237 -12.688 1.00 9.38 ? 887 PRO A CA 1 ATOM 7087 C C . PRO A 1 887 ? 37.749 80.971 -12.784 1.00 8.50 ? 887 PRO A C 1 ATOM 7088 O O . PRO A 1 887 ? 38.808 80.830 -12.179 1.00 9.48 ? 887 PRO A O 1 ATOM 7089 C CB . PRO A 1 887 ? 37.640 83.404 -13.433 1.00 10.18 ? 887 PRO A CB 1 ATOM 7090 C CG . PRO A 1 887 ? 37.160 84.611 -12.635 1.00 11.70 ? 887 PRO A CG 1 ATOM 7091 C CD . PRO A 1 887 ? 37.187 84.156 -11.208 1.00 10.40 ? 887 PRO A CD 1 ATOM 7092 N N . VAL A 1 888 ? 37.248 80.019 -13.559 1.00 8.40 ? 888 VAL A N 1 ATOM 7093 C CA . VAL A 1 888 ? 37.930 78.743 -13.744 1.00 8.19 ? 888 VAL A CA 1 ATOM 7094 C C . VAL A 1 888 ? 37.837 78.361 -15.200 1.00 7.86 ? 888 VAL A C 1 ATOM 7095 O O . VAL A 1 888 ? 36.795 78.619 -15.884 1.00 8.90 ? 888 VAL A O 1 ATOM 7096 C CB . VAL A 1 888 ? 37.265 77.613 -12.832 1.00 8.28 ? 888 VAL A CB 1 ATOM 7097 C CG1 . VAL A 1 888 ? 35.731 77.496 -13.085 1.00 10.02 ? 888 VAL A CG1 1 ATOM 7098 C CG2 . VAL A 1 888 ? 37.935 76.301 -13.085 1.00 8.76 ? 888 VAL A CG2 1 ATOM 7099 N N . LEU A 1 889 ? 38.913 77.802 -15.730 1.00 7.68 ? 889 LEU A N 1 ATOM 7100 C CA . LEU A 1 889 ? 38.944 77.312 -17.101 1.00 7.79 ? 889 LEU A CA 1 ATOM 7101 C C . LEU A 1 889 ? 38.730 75.780 -17.131 1.00 8.04 ? 889 LEU A C 1 ATOM 7102 O O . LEU A 1 889 ? 39.626 74.986 -16.818 1.00 8.97 ? 889 LEU A O 1 ATOM 7103 C CB . LEU A 1 889 ? 40.266 77.659 -17.789 1.00 9.43 ? 889 LEU A CB 1 ATOM 7104 C CG . LEU A 1 889 ? 40.345 77.269 -19.286 1.00 9.72 ? 889 LEU A CG 1 ATOM 7105 C CD1 . LEU A 1 889 ? 39.412 78.187 -20.096 1.00 12.07 ? 889 LEU A CD1 1 ATOM 7106 C CD2 . LEU A 1 889 ? 41.791 77.340 -19.779 1.00 13.50 ? 889 LEU A CD2 1 ATOM 7107 N N . HIS A 1 890 ? 37.508 75.385 -17.472 1.00 6.95 ? 890 HIS A N 1 ATOM 7108 C CA . HIS A 1 890 ? 37.213 73.960 -17.596 1.00 7.13 ? 890 HIS A CA 1 ATOM 7109 C C . HIS A 1 890 ? 37.556 73.474 -18.994 1.00 7.34 ? 890 HIS A C 1 ATOM 7110 O O . HIS A 1 890 ? 37.335 74.214 -19.993 1.00 7.74 ? 890 HIS A O 1 ATOM 7111 C CB . HIS A 1 890 ? 35.723 73.696 -17.380 1.00 7.50 ? 890 HIS A CB 1 ATOM 7112 C CG . HIS A 1 890 ? 35.271 73.899 -15.969 1.00 7.66 ? 890 HIS A CG 1 ATOM 7113 N ND1 . HIS A 1 890 ? 36.065 73.520 -14.903 1.00 9.15 ? 890 HIS A ND1 1 ATOM 7114 C CD2 . HIS A 1 890 ? 34.097 74.314 -15.441 1.00 9.30 ? 890 HIS A CD2 1 ATOM 7115 C CE1 . HIS A 1 890 ? 35.386 73.680 -13.778 1.00 9.58 ? 890 HIS A CE1 1 ATOM 7116 N NE2 . HIS A 1 890 ? 34.184 74.162 -14.079 1.00 8.50 ? 890 HIS A NE2 1 ATOM 7117 N N . ILE A 1 891 ? 38.098 72.266 -19.105 1.00 6.48 ? 891 ILE A N 1 ATOM 7118 C CA . ILE A 1 891 ? 38.492 71.711 -20.387 1.00 7.09 ? 891 ILE A CA 1 ATOM 7119 C C . ILE A 1 891 ? 37.841 70.352 -20.621 1.00 6.42 ? 891 ILE A C 1 ATOM 7120 O O . ILE A 1 891 ? 37.564 69.587 -19.690 1.00 6.62 ? 891 ILE A O 1 ATOM 7121 C CB . ILE A 1 891 ? 40.034 71.660 -20.519 1.00 7.02 ? 891 ILE A CB 1 ATOM 7122 C CG1 . ILE A 1 891 ? 40.648 70.659 -19.541 1.00 9.50 ? 891 ILE A CG1 1 ATOM 7123 C CG2 . ILE A 1 891 ? 40.625 73.047 -20.279 1.00 9.95 ? 891 ILE A CG2 1 ATOM 7124 C CD1 . ILE A 1 891 ? 42.202 70.496 -19.775 1.00 10.40 ? 891 ILE A CD1 1 ATOM 7125 N N . TYR A 1 892 ? 37.585 70.089 -21.904 1.00 6.39 ? 892 TYR A N 1 ATOM 7126 C CA . TYR A 1 892 ? 36.924 68.857 -22.346 1.00 6.18 ? 892 TYR A CA 1 ATOM 7127 C C . TYR A 1 892 ? 37.342 68.428 -23.714 1.00 6.14 ? 892 TYR A C 1 ATOM 7128 O O . TYR A 1 892 ? 37.923 69.218 -24.479 1.00 6.90 ? 892 TYR A O 1 ATOM 7129 C CB . TYR A 1 892 ? 35.389 69.077 -22.468 1.00 6.89 ? 892 TYR A CB 1 ATOM 7130 C CG . TYR A 1 892 ? 34.723 69.766 -21.296 1.00 6.10 ? 892 TYR A CG 1 ATOM 7131 C CD1 . TYR A 1 892 ? 34.714 71.161 -21.188 1.00 6.70 ? 892 TYR A CD1 1 ATOM 7132 C CD2 . TYR A 1 892 ? 34.130 68.998 -20.267 1.00 6.73 ? 892 TYR A CD2 1 ATOM 7133 C CE1 . TYR A 1 892 ? 34.126 71.774 -20.082 1.00 7.15 ? 892 TYR A CE1 1 ATOM 7134 C CE2 . TYR A 1 892 ? 33.552 69.582 -19.184 1.00 6.85 ? 892 TYR A CE2 1 ATOM 7135 C CZ . TYR A 1 892 ? 33.542 70.974 -19.082 1.00 7.08 ? 892 TYR A CZ 1 ATOM 7136 O OH . TYR A 1 892 ? 32.933 71.533 -17.977 1.00 8.16 ? 892 TYR A OH 1 ATOM 7137 N N . ARG A 1 893 ? 37.056 67.166 -24.026 1.00 6.53 ? 893 ARG A N 1 ATOM 7138 C CA . ARG A 1 893 ? 37.168 66.687 -25.438 1.00 7.41 ? 893 ARG A CA 1 ATOM 7139 C C . ARG A 1 893 ? 35.800 66.079 -25.761 1.00 7.30 ? 893 ARG A C 1 ATOM 7140 O O . ARG A 1 893 ? 35.172 65.444 -24.924 1.00 8.27 ? 893 ARG A O 1 ATOM 7141 C CB . ARG A 1 893 ? 38.221 65.635 -25.678 1.00 6.95 ? 893 ARG A CB 1 ATOM 7142 C CG . ARG A 1 893 ? 39.633 66.174 -25.400 1.00 8.13 ? 893 ARG A CG 1 ATOM 7143 C CD . ARG A 1 893 ? 40.064 67.296 -26.417 1.00 8.82 ? 893 ARG A CD 1 ATOM 7144 N NE . ARG A 1 893 ? 40.242 66.763 -27.764 1.00 9.32 ? 893 ARG A NE 1 ATOM 7145 C CZ . ARG A 1 893 ? 41.316 66.104 -28.206 1.00 9.13 ? 893 ARG A CZ 1 ATOM 7146 N NH1 . ARG A 1 893 ? 42.372 65.891 -27.406 1.00 11.12 ? 893 ARG A NH1 1 ATOM 7147 N NH2 . ARG A 1 893 ? 41.354 65.645 -29.470 1.00 11.73 ? 893 ARG A NH2 1 ATOM 7148 N N . LEU A 1 894 ? 35.350 66.271 -27.002 1.00 8.33 ? 894 LEU A N 1 ATOM 7149 C CA . LEU A 1 894 ? 34.028 65.785 -27.438 1.00 9.66 ? 894 LEU A CA 1 ATOM 7150 C C . LEU A 1 894 ? 34.251 64.807 -28.593 1.00 9.16 ? 894 LEU A C 1 ATOM 7151 O O . LEU A 1 894 ? 34.760 65.176 -29.634 1.00 10.29 ? 894 LEU A O 1 ATOM 7152 C CB . LEU A 1 894 ? 33.204 66.976 -27.903 1.00 10.42 ? 894 LEU A CB 1 ATOM 7153 C CG . LEU A 1 894 ? 31.773 66.583 -28.298 1.00 11.87 ? 894 LEU A CG 1 ATOM 7154 C CD1 . LEU A 1 894 ? 30.984 66.084 -27.107 1.00 14.71 ? 894 LEU A CD1 1 ATOM 7155 C CD2 . LEU A 1 894 ? 31.090 67.834 -28.876 1.00 15.22 ? 894 LEU A CD2 1 ATOM 7156 N N . VAL A 1 895 ? 33.900 63.547 -28.363 1.00 9.41 ? 895 VAL A N 1 ATOM 7157 C CA . VAL A 1 895 ? 34.126 62.491 -29.353 1.00 10.16 ? 895 VAL A CA 1 ATOM 7158 C C . VAL A 1 895 ? 32.816 61.848 -29.826 1.00 10.39 ? 895 VAL A C 1 ATOM 7159 O O . VAL A 1 895 ? 32.112 61.157 -29.075 1.00 10.17 ? 895 VAL A O 1 ATOM 7160 C CB . VAL A 1 895 ? 34.984 61.384 -28.720 1.00 10.39 ? 895 VAL A CB 1 ATOM 7161 C CG1 . VAL A 1 895 ? 35.352 60.378 -29.801 1.00 13.54 ? 895 VAL A CG1 1 ATOM 7162 C CG2 . VAL A 1 895 ? 36.267 61.982 -28.047 1.00 13.12 ? 895 VAL A CG2 1 ATOM 7163 N N . LEU A 1 896 ? 32.458 62.149 -31.075 1.00 10.77 ? 896 LEU A N 1 ATOM 7164 C CA . LEU A 1 896 ? 31.279 61.539 -31.723 1.00 11.15 ? 896 LEU A CA 1 ATOM 7165 C C . LEU A 1 896 ? 31.846 60.404 -32.555 1.00 10.74 ? 896 LEU A C 1 ATOM 7166 O O . LEU A 1 896 ? 32.768 60.587 -33.321 1.00 12.02 ? 896 LEU A O 1 ATOM 7167 C CB . LEU A 1 896 ? 30.606 62.561 -32.648 1.00 11.11 ? 896 LEU A CB 1 ATOM 7168 C CG . LEU A 1 896 ? 29.429 61.913 -33.422 1.00 12.32 ? 896 LEU A CG 1 ATOM 7169 C CD1 . LEU A 1 896 ? 28.301 61.649 -32.524 1.00 13.39 ? 896 LEU A CD1 1 ATOM 7170 C CD2 . LEU A 1 896 ? 28.946 62.890 -34.488 1.00 13.76 ? 896 LEU A CD2 1 ATOM 7171 N N . GLU A 1 897 ? 31.285 59.192 -32.390 1.00 10.59 ? 897 GLU A N 1 ATOM 7172 C CA . GLU A 1 897 ? 31.798 58.044 -33.129 1.00 12.00 ? 897 GLU A CA 1 ATOM 7173 C C . GLU A 1 897 ? 30.718 57.057 -33.540 1.00 11.71 ? 897 GLU A C 1 ATOM 7174 O O . GLU A 1 897 ? 29.677 56.951 -32.896 1.00 12.12 ? 897 GLU A O 1 ATOM 7175 C CB . GLU A 1 897 ? 32.763 57.240 -32.233 1.00 14.38 ? 897 GLU A CB 1 ATOM 7176 C CG . GLU A 1 897 ? 33.847 58.011 -31.507 1.00 17.01 ? 897 GLU A CG 1 ATOM 7177 C CD . GLU A 1 897 ? 34.506 57.103 -30.400 1.00 16.48 ? 897 GLU A CD 1 ATOM 7178 O OE1 . GLU A 1 897 ? 33.899 56.893 -29.311 1.00 18.62 ? 897 GLU A OE1 1 ATOM 7179 O OE2 . GLU A 1 897 ? 35.631 56.678 -30.690 1.00 22.15 ? 897 GLU A OE2 1 ATOM 7180 N N . LYS A 1 898 ? 31.016 56.309 -34.608 1.00 12.95 ? 898 LYS A N 1 ATOM 7181 C CA . LYS A 1 898 ? 30.126 55.219 -34.999 1.00 14.11 ? 898 LYS A CA 1 ATOM 7182 C C . LYS A 1 898 ? 30.589 54.006 -34.187 1.00 14.51 ? 898 LYS A C 1 ATOM 7183 O O . LYS A 1 898 ? 31.794 53.700 -34.102 1.00 17.68 ? 898 LYS A O 1 ATOM 7184 C CB . LYS A 1 898 ? 30.276 54.937 -36.493 1.00 16.68 ? 898 LYS A CB 1 ATOM 7185 C CG . LYS A 1 898 ? 29.890 56.072 -37.427 1.00 19.95 ? 898 LYS A CG 1 ATOM 7186 C CD . LYS A 1 898 ? 28.630 56.918 -37.034 1.00 23.86 ? 898 LYS A CD 1 ATOM 7187 C CE . LYS A 1 898 ? 27.297 56.123 -36.829 1.00 24.95 ? 898 LYS A CE 1 ATOM 7188 N NZ . LYS A 1 898 ? 27.115 54.912 -37.694 1.00 27.86 ? 898 LYS A NZ 1 ATOM 7189 N N . VAL A 1 899 ? 29.658 53.308 -33.581 1.00 14.48 ? 899 VAL A N 1 ATOM 7190 C CA . VAL A 1 899 ? 30.027 52.158 -32.769 1.00 14.80 ? 899 VAL A CA 1 ATOM 7191 C C . VAL A 1 899 ? 29.281 50.868 -33.147 1.00 15.31 ? 899 VAL A C 1 ATOM 7192 O O . VAL A 1 899 ? 29.369 49.888 -32.445 1.00 14.75 ? 899 VAL A O 1 ATOM 7193 C CB . VAL A 1 899 ? 29.796 52.453 -31.264 1.00 14.67 ? 899 VAL A CB 1 ATOM 7194 C CG1 . VAL A 1 899 ? 30.801 53.546 -30.790 1.00 15.70 ? 899 VAL A CG1 1 ATOM 7195 C CG2 . VAL A 1 899 ? 28.391 52.947 -31.030 1.00 14.55 ? 899 VAL A CG2 1 ATOM 7196 N N . ASN A 1 900 ? 28.574 50.856 -34.280 1.00 15.70 ? 900 ASN A N 1 ATOM 7197 C CA . ASN A 1 900 ? 27.854 49.637 -34.626 1.00 17.08 ? 900 ASN A CA 1 ATOM 7198 C C . ASN A 1 900 ? 28.798 48.473 -34.917 1.00 16.20 ? 900 ASN A C 1 ATOM 7199 O O . ASN A 1 900 ? 28.336 47.319 -34.851 1.00 18.34 ? 900 ASN A O 1 ATOM 7200 C CB . ASN A 1 900 ? 26.948 49.853 -35.841 1.00 19.02 ? 900 ASN A CB 1 ATOM 7201 C CG . ASN A 1 900 ? 27.684 50.388 -37.011 1.00 20.64 ? 900 ASN A CG 1 ATOM 7202 O OD1 . ASN A 1 900 ? 28.288 51.456 -36.964 1.00 22.45 ? 900 ASN A OD1 1 ATOM 7203 N ND2 . ASN A 1 900 ? 27.636 49.633 -38.130 1.00 24.12 ? 900 ASN A ND2 1 ATOM 7204 N N . ASN A 1 901 ? 30.071 48.718 -35.216 1.00 14.90 ? 901 ASN A N 1 ATOM 7205 C CA . ASN A 1 901 ? 30.987 47.610 -35.475 1.00 15.76 ? 901 ASN A CA 1 ATOM 7206 C C . ASN A 1 901 ? 31.797 47.218 -34.237 1.00 14.51 ? 901 ASN A C 1 ATOM 7207 O O . ASN A 1 901 ? 32.578 46.281 -34.277 1.00 15.01 ? 901 ASN A O 1 ATOM 7208 C CB . ASN A 1 901 ? 31.971 47.979 -36.567 1.00 18.64 ? 901 ASN A CB 1 ATOM 7209 C CG . ASN A 1 901 ? 31.336 48.032 -37.914 1.00 21.38 ? 901 ASN A CG 1 ATOM 7210 O OD1 . ASN A 1 901 ? 31.588 48.967 -38.686 1.00 26.12 ? 901 ASN A OD1 1 ATOM 7211 N ND2 . ASN A 1 901 ? 30.533 47.044 -38.227 1.00 22.68 ? 901 ASN A ND2 1 ATOM 7212 N N . CYS A 1 902 ? 31.571 47.901 -33.125 1.00 13.42 ? 902 CYS A N 1 ATOM 7213 C CA . CYS A 1 902 ? 32.344 47.588 -31.917 1.00 13.49 ? 902 CYS A CA 1 ATOM 7214 C C . CYS A 1 902 ? 31.794 46.398 -31.164 1.00 13.58 ? 902 CYS A C 1 ATOM 7215 O O . CYS A 1 902 ? 30.573 46.221 -31.086 1.00 14.70 ? 902 CYS A O 1 ATOM 7216 C CB . CYS A 1 902 ? 32.309 48.774 -30.951 1.00 14.25 ? 902 CYS A CB 1 ATOM 7217 S SG . CYS A 1 902 ? 33.061 50.316 -31.533 1.00 16.03 ? 902 CYS A SG 1 ATOM 7218 N N . VAL A 1 903 ? 32.674 45.593 -30.585 1.00 12.39 ? 903 VAL A N 1 ATOM 7219 C CA . VAL A 1 903 ? 32.248 44.465 -29.749 1.00 13.14 ? 903 VAL A CA 1 ATOM 7220 C C . VAL A 1 903 ? 31.965 45.050 -28.355 1.00 12.70 ? 903 VAL A C 1 ATOM 7221 O O . VAL A 1 903 ? 32.894 45.393 -27.586 1.00 14.46 ? 903 VAL A O 1 ATOM 7222 C CB . VAL A 1 903 ? 33.371 43.397 -29.706 1.00 13.08 ? 903 VAL A CB 1 ATOM 7223 C CG1 . VAL A 1 903 ? 32.955 42.243 -28.781 1.00 13.88 ? 903 VAL A CG1 1 ATOM 7224 C CG2 . VAL A 1 903 ? 33.595 42.808 -31.109 1.00 14.32 ? 903 VAL A CG2 1 ATOM 7225 N N . ARG A 1 904 ? 30.703 45.192 -28.033 1.00 12.63 ? 904 ARG A N 1 ATOM 7226 C CA . ARG A 1 904 ? 30.306 45.777 -26.750 1.00 12.27 ? 904 ARG A CA 1 ATOM 7227 C C . ARG A 1 904 ? 29.779 44.721 -25.807 1.00 12.74 ? 904 ARG A C 1 ATOM 7228 O O . ARG A 1 904 ? 29.421 43.597 -26.217 1.00 13.38 ? 904 ARG A O 1 ATOM 7229 C CB . ARG A 1 904 ? 29.190 46.811 -26.978 1.00 13.41 ? 904 ARG A CB 1 ATOM 7230 C CG . ARG A 1 904 ? 29.772 48.081 -27.637 1.00 15.30 ? 904 ARG A CG 1 ATOM 7231 C CD . ARG A 1 904 ? 28.751 49.186 -27.907 1.00 17.59 ? 904 ARG A CD 1 ATOM 7232 N NE . ARG A 1 904 ? 28.007 48.856 -29.095 1.00 17.98 ? 904 ARG A NE 1 ATOM 7233 C CZ . ARG A 1 904 ? 27.008 49.601 -29.578 1.00 19.07 ? 904 ARG A CZ 1 ATOM 7234 N NH1 . ARG A 1 904 ? 26.623 50.721 -28.972 1.00 19.48 ? 904 ARG A NH1 1 ATOM 7235 N NH2 . ARG A 1 904 ? 26.399 49.187 -30.685 1.00 19.75 ? 904 ARG A NH2 1 ATOM 7236 N N . PRO A 1 905 ? 29.741 45.053 -24.512 1.00 11.36 ? 905 PRO A N 1 ATOM 7237 C CA . PRO A 1 905 ? 29.199 44.121 -23.526 1.00 12.35 ? 905 PRO A CA 1 ATOM 7238 C C . PRO A 1 905 ? 27.713 43.913 -23.862 1.00 12.85 ? 905 PRO A C 1 ATOM 7239 O O . PRO A 1 905 ? 27.071 44.733 -24.527 1.00 12.80 ? 905 PRO A O 1 ATOM 7240 C CB . PRO A 1 905 ? 29.307 44.892 -22.206 1.00 11.02 ? 905 PRO A CB 1 ATOM 7241 C CG . PRO A 1 905 ? 30.458 45.875 -22.470 1.00 10.66 ? 905 PRO A CG 1 ATOM 7242 C CD . PRO A 1 905 ? 30.195 46.321 -23.889 1.00 11.38 ? 905 PRO A CD 1 ATOM 7243 N N . SER A 1 906 ? 27.176 42.787 -23.403 1.00 12.24 ? 906 SER A N 1 ATOM 7244 C CA . SER A 1 906 ? 25.763 42.493 -23.576 1.00 15.47 ? 906 SER A CA 1 ATOM 7245 C C . SER A 1 906 ? 24.905 43.486 -22.770 1.00 15.71 ? 906 SER A C 1 ATOM 7246 O O . SER A 1 906 ? 25.407 44.204 -21.866 1.00 15.64 ? 906 SER A O 1 ATOM 7247 C CB . SER A 1 906 ? 25.515 41.103 -23.040 1.00 17.81 ? 906 SER A CB 1 ATOM 7248 O OG . SER A 1 906 ? 25.182 41.225 -21.666 1.00 22.90 ? 906 SER A OG 1 ATOM 7249 N N . LYS A 1 907 ? 23.615 43.542 -23.060 1.00 16.43 ? 907 LYS A N 1 ATOM 7250 C CA . LYS A 1 907 ? 22.682 44.441 -22.387 1.00 18.19 ? 907 LYS A CA 1 ATOM 7251 C C . LYS A 1 907 ? 22.660 44.253 -20.883 1.00 17.79 ? 907 LYS A C 1 ATOM 7252 O O . LYS A 1 907 ? 22.371 45.205 -20.171 1.00 19.05 ? 907 LYS A O 1 ATOM 7253 C CB . LYS A 1 907 ? 21.266 44.241 -22.959 1.00 21.06 ? 907 LYS A CB 1 ATOM 7254 C CG . LYS A 1 907 ? 21.216 44.540 -24.445 1.00 26.34 ? 907 LYS A CG 1 ATOM 7255 C CD . LYS A 1 907 ? 19.813 44.338 -25.014 1.00 29.85 ? 907 LYS A CD 1 ATOM 7256 C CE . LYS A 1 907 ? 19.688 44.857 -26.437 1.00 32.39 ? 907 LYS A CE 1 ATOM 7257 N NZ . LYS A 1 907 ? 18.265 44.677 -26.910 1.00 34.60 ? 907 LYS A NZ 1 ATOM 7258 N N . LEU A 1 908 ? 22.976 43.070 -20.371 1.00 16.21 ? 908 LEU A N 1 ATOM 7259 C CA . LEU A 1 908 ? 22.947 42.901 -18.907 1.00 16.26 ? 908 LEU A CA 1 ATOM 7260 C C . LEU A 1 908 ? 24.268 43.247 -18.196 1.00 14.17 ? 908 LEU A C 1 ATOM 7261 O O . LEU A 1 908 ? 24.326 43.224 -16.957 1.00 14.87 ? 908 LEU A O 1 ATOM 7262 C CB . LEU A 1 908 ? 22.526 41.458 -18.528 1.00 18.64 ? 908 LEU A CB 1 ATOM 7263 C CG . LEU A 1 908 ? 21.071 41.134 -18.915 1.00 20.22 ? 908 LEU A CG 1 ATOM 7264 C CD1 . LEU A 1 908 ? 20.838 39.632 -18.754 1.00 21.10 ? 908 LEU A CD1 1 ATOM 7265 C CD2 . LEU A 1 908 ? 20.115 41.920 -18.040 1.00 22.12 ? 908 LEU A CD2 1 ATOM 7266 N N . HIS A 1 909 ? 25.323 43.570 -18.941 1.00 12.18 ? 909 HIS A N 1 ATOM 7267 C CA . HIS A 1 909 ? 26.603 43.868 -18.309 1.00 11.74 ? 909 HIS A CA 1 ATOM 7268 C C . HIS A 1 909 ? 26.546 45.257 -17.661 1.00 10.97 ? 909 HIS A C 1 ATOM 7269 O O . HIS A 1 909 ? 26.038 46.203 -18.259 1.00 11.01 ? 909 HIS A O 1 ATOM 7270 C CB . HIS A 1 909 ? 27.684 43.842 -19.352 1.00 11.72 ? 909 HIS A CB 1 ATOM 7271 C CG . HIS A 1 909 ? 29.033 43.614 -18.796 1.00 11.00 ? 909 HIS A CG 1 ATOM 7272 N ND1 . HIS A 1 909 ? 29.702 44.575 -18.060 1.00 11.39 ? 909 HIS A ND1 1 ATOM 7273 C CD2 . HIS A 1 909 ? 29.859 42.539 -18.859 1.00 11.81 ? 909 HIS A CD2 1 ATOM 7274 C CE1 . HIS A 1 909 ? 30.883 44.101 -17.718 1.00 11.25 ? 909 HIS A CE1 1 ATOM 7275 N NE2 . HIS A 1 909 ? 31.016 42.868 -18.202 1.00 12.03 ? 909 HIS A NE2 1 ATOM 7276 N N . PRO A 1 910 ? 27.032 45.381 -16.425 1.00 10.51 ? 910 PRO A N 1 ATOM 7277 C CA . PRO A 1 910 ? 26.972 46.713 -15.780 1.00 9.55 ? 910 PRO A CA 1 ATOM 7278 C C . PRO A 1 910 ? 28.074 47.719 -16.147 1.00 7.98 ? 910 PRO A C 1 ATOM 7279 O O . PRO A 1 910 ? 28.012 48.828 -15.605 1.00 9.06 ? 910 PRO A O 1 ATOM 7280 C CB . PRO A 1 910 ? 27.009 46.419 -14.279 1.00 10.09 ? 910 PRO A CB 1 ATOM 7281 C CG . PRO A 1 910 ? 27.107 44.906 -14.136 1.00 12.62 ? 910 PRO A CG 1 ATOM 7282 C CD . PRO A 1 910 ? 27.422 44.302 -15.479 1.00 10.36 ? 910 PRO A CD 1 ATOM 7283 N N . ALA A 1 911 ? 29.034 47.327 -16.970 1.00 8.49 ? 911 ALA A N 1 ATOM 7284 C CA . ALA A 1 911 ? 30.141 48.232 -17.337 1.00 8.75 ? 911 ALA A CA 1 ATOM 7285 C C . ALA A 1 911 ? 30.024 48.715 -18.759 1.00 8.78 ? 911 ALA A C 1 ATOM 7286 O O . ALA A 1 911 ? 29.286 48.118 -19.609 1.00 10.12 ? 911 ALA A O 1 ATOM 7287 C CB . ALA A 1 911 ? 31.474 47.518 -17.223 1.00 9.34 ? 911 ALA A CB 1 ATOM 7288 N N . GLY A 1 912 ? 30.781 49.775 -19.041 1.00 8.71 ? 912 GLY A N 1 ATOM 7289 C CA . GLY A 1 912 ? 30.976 50.198 -20.419 1.00 9.17 ? 912 GLY A CA 1 ATOM 7290 C C . GLY A 1 912 ? 32.471 50.478 -20.569 1.00 8.61 ? 912 GLY A C 1 ATOM 7291 O O . GLY A 1 912 ? 33.199 50.574 -19.568 1.00 9.30 ? 912 GLY A O 1 ATOM 7292 N N . TYR A 1 913 ? 32.932 50.653 -21.799 1.00 8.64 ? 913 TYR A N 1 ATOM 7293 C CA . TYR A 1 913 ? 34.335 50.860 -22.096 1.00 8.65 ? 913 TYR A CA 1 ATOM 7294 C C . TYR A 1 913 ? 34.488 51.883 -23.199 1.00 9.24 ? 913 TYR A C 1 ATOM 7295 O O . TYR A 1 913 ? 33.677 51.910 -24.150 1.00 9.76 ? 913 TYR A O 1 ATOM 7296 C CB . TYR A 1 913 ? 34.995 49.523 -22.568 1.00 9.75 ? 913 TYR A CB 1 ATOM 7297 C CG . TYR A 1 913 ? 34.972 48.461 -21.472 1.00 8.75 ? 913 TYR A CG 1 ATOM 7298 C CD1 . TYR A 1 913 ? 35.863 48.504 -20.431 1.00 8.72 ? 913 TYR A CD1 1 ATOM 7299 C CD2 . TYR A 1 913 ? 33.976 47.475 -21.462 1.00 9.76 ? 913 TYR A CD2 1 ATOM 7300 C CE1 . TYR A 1 913 ? 35.797 47.645 -19.393 1.00 9.27 ? 913 TYR A CE1 1 ATOM 7301 C CE2 . TYR A 1 913 ? 33.868 46.558 -20.408 1.00 9.88 ? 913 TYR A CE2 1 ATOM 7302 C CZ . TYR A 1 913 ? 34.806 46.670 -19.361 1.00 8.63 ? 913 TYR A CZ 1 ATOM 7303 O OH . TYR A 1 913 ? 34.727 45.802 -18.304 1.00 10.75 ? 913 TYR A OH 1 ATOM 7304 N N . LEU A 1 914 ? 35.574 52.634 -23.095 1.00 9.33 ? 914 LEU A N 1 ATOM 7305 C CA . LEU A 1 914 ? 35.893 53.651 -24.083 1.00 9.78 ? 914 LEU A CA 1 ATOM 7306 C C . LEU A 1 914 ? 36.454 53.026 -25.335 1.00 10.10 ? 914 LEU A C 1 ATOM 7307 O O . LEU A 1 914 ? 36.969 51.890 -25.347 1.00 10.68 ? 914 LEU A O 1 ATOM 7308 C CB . LEU A 1 914 ? 36.978 54.624 -23.523 1.00 9.01 ? 914 LEU A CB 1 ATOM 7309 C CG . LEU A 1 914 ? 36.498 55.483 -22.359 1.00 8.47 ? 914 LEU A CG 1 ATOM 7310 C CD1 . LEU A 1 914 ? 37.564 56.520 -22.120 1.00 10.42 ? 914 LEU A CD1 1 ATOM 7311 C CD2 . LEU A 1 914 ? 35.178 56.207 -22.635 1.00 9.49 ? 914 LEU A CD2 1 ATOM 7312 N N . THR A 1 915 ? 36.353 53.801 -26.413 1.00 9.91 ? 915 THR A N 1 ATOM 7313 C CA . THR A 1 915 ? 37.080 53.455 -27.628 1.00 9.46 ? 915 THR A CA 1 ATOM 7314 C C . THR A 1 915 ? 38.506 54.034 -27.506 1.00 10.24 ? 915 THR A C 1 ATOM 7315 O O . THR A 1 915 ? 38.845 54.858 -26.596 1.00 10.38 ? 915 THR A O 1 ATOM 7316 C CB . THR A 1 915 ? 36.473 54.137 -28.844 1.00 11.05 ? 915 THR A CB 1 ATOM 7317 O OG1 . THR A 1 915 ? 36.465 55.555 -28.543 1.00 12.26 ? 915 THR A OG1 1 ATOM 7318 C CG2 . THR A 1 915 ? 35.023 53.652 -29.128 1.00 12.13 ? 915 THR A CG2 1 ATOM 7319 N N . SER A 1 916 ? 39.366 53.632 -28.405 1.00 10.42 ? 916 SER A N 1 ATOM 7320 C CA . SER A 1 916 ? 40.715 54.128 -28.470 1.00 11.02 ? 916 SER A CA 1 ATOM 7321 C C . SER A 1 916 ? 40.746 55.670 -28.566 1.00 10.57 ? 916 SER A C 1 ATOM 7322 O O . SER A 1 916 ? 41.471 56.333 -27.812 1.00 10.31 ? 916 SER A O 1 ATOM 7323 C CB . SER A 1 916 ? 41.413 53.576 -29.704 1.00 12.85 ? 916 SER A CB 1 ATOM 7324 O OG . SER A 1 916 ? 42.623 54.263 -29.859 1.00 19.79 ? 916 SER A OG 1 ATOM 7325 N N . ALA A 1 917 ? 39.956 56.256 -29.448 1.00 9.59 ? 917 ALA A N 1 ATOM 7326 C CA . ALA A 1 917 ? 39.978 57.701 -29.568 1.00 9.86 ? 917 ALA A CA 1 ATOM 7327 C C . ALA A 1 917 ? 39.518 58.418 -28.331 1.00 9.67 ? 917 ALA A C 1 ATOM 7328 O O . ALA A 1 917 ? 40.069 59.464 -28.006 1.00 9.32 ? 917 ALA A O 1 ATOM 7329 C CB . ALA A 1 917 ? 39.078 58.139 -30.741 1.00 11.78 ? 917 ALA A CB 1 ATOM 7330 N N . ALA A 1 918 ? 38.503 57.888 -27.628 1.00 9.07 ? 918 ALA A N 1 ATOM 7331 C CA . ALA A 1 918 ? 38.048 58.600 -26.430 1.00 8.98 ? 918 ALA A CA 1 ATOM 7332 C C . ALA A 1 918 ? 39.082 58.450 -25.324 1.00 8.53 ? 918 ALA A C 1 ATOM 7333 O O . ALA A 1 918 ? 39.292 59.409 -24.528 1.00 8.63 ? 918 ALA A O 1 ATOM 7334 C CB . ALA A 1 918 ? 36.706 58.067 -26.022 1.00 9.13 ? 918 ALA A CB 1 ATOM 7335 N N . HIS A 1 919 ? 39.689 57.273 -25.195 1.00 7.55 ? 919 HIS A N 1 ATOM 7336 C CA . HIS A 1 919 ? 40.739 57.104 -24.184 1.00 8.53 ? 919 HIS A CA 1 ATOM 7337 C C . HIS A 1 919 ? 41.912 58.049 -24.472 1.00 8.18 ? 919 HIS A C 1 ATOM 7338 O O . HIS A 1 919 ? 42.424 58.714 -23.530 1.00 8.67 ? 919 HIS A O 1 ATOM 7339 C CB . HIS A 1 919 ? 41.200 55.645 -24.182 1.00 9.77 ? 919 HIS A CB 1 ATOM 7340 C CG . HIS A 1 919 ? 42.353 55.399 -23.260 1.00 10.38 ? 919 HIS A CG 1 ATOM 7341 N ND1 . HIS A 1 919 ? 43.606 55.051 -23.710 1.00 13.68 ? 919 HIS A ND1 1 ATOM 7342 C CD2 . HIS A 1 919 ? 42.436 55.490 -21.911 1.00 11.12 ? 919 HIS A CD2 1 ATOM 7343 C CE1 . HIS A 1 919 ? 44.423 54.922 -22.673 1.00 12.99 ? 919 HIS A CE1 1 ATOM 7344 N NE2 . HIS A 1 919 ? 43.747 55.195 -21.581 1.00 12.75 ? 919 HIS A NE2 1 ATOM 7345 N N . LYS A 1 920 ? 42.364 58.131 -25.727 1.00 8.62 ? 920 LYS A N 1 ATOM 7346 C CA . LYS A 1 920 ? 43.462 59.046 -26.030 1.00 9.53 ? 920 LYS A CA 1 ATOM 7347 C C . LYS A 1 920 ? 43.049 60.493 -25.747 1.00 8.41 ? 920 LYS A C 1 ATOM 7348 O O . LYS A 1 920 ? 43.881 61.280 -25.277 1.00 8.57 ? 920 LYS A O 1 ATOM 7349 C CB . LYS A 1 920 ? 43.914 58.871 -27.470 1.00 11.54 ? 920 LYS A CB 1 ATOM 7350 C CG . LYS A 1 920 ? 44.754 57.615 -27.604 1.00 14.42 ? 920 LYS A CG 1 ATOM 7351 C CD . LYS A 1 920 ? 45.601 57.631 -28.915 1.00 17.82 ? 920 LYS A CD 1 ATOM 7352 C CE . LYS A 1 920 ? 46.517 56.418 -29.039 1.00 19.58 ? 920 LYS A CE 1 ATOM 7353 N NZ . LYS A 1 920 ? 47.705 56.487 -28.152 1.00 17.58 ? 920 LYS A NZ 1 ATOM 7354 N N . ALA A 1 921 ? 41.798 60.848 -26.038 1.00 8.04 ? 921 ALA A N 1 ATOM 7355 C CA . ALA A 1 921 ? 41.334 62.224 -25.768 1.00 8.43 ? 921 ALA A CA 1 ATOM 7356 C C . ALA A 1 921 ? 41.407 62.494 -24.248 1.00 7.80 ? 921 ALA A C 1 ATOM 7357 O O . ALA A 1 921 ? 41.776 63.597 -23.820 1.00 8.34 ? 921 ALA A O 1 ATOM 7358 C CB . ALA A 1 921 ? 39.886 62.403 -26.338 1.00 7.77 ? 921 ALA A CB 1 ATOM 7359 N N . SER A 1 922 ? 41.035 61.504 -23.435 1.00 7.52 ? 922 SER A N 1 ATOM 7360 C CA . SER A 1 922 ? 41.115 61.688 -21.979 1.00 7.25 ? 922 SER A CA 1 ATOM 7361 C C . SER A 1 922 ? 42.572 61.888 -21.556 1.00 8.03 ? 922 SER A C 1 ATOM 7362 O O . SER A 1 922 ? 42.843 62.772 -20.724 1.00 8.78 ? 922 SER A O 1 ATOM 7363 C CB . SER A 1 922 ? 40.518 60.444 -21.291 1.00 7.35 ? 922 SER A CB 1 ATOM 7364 O OG . SER A 1 922 ? 40.655 60.616 -19.864 1.00 7.69 ? 922 SER A OG 1 ATOM 7365 N N . GLN A 1 923 ? 43.478 61.080 -22.095 1.00 7.75 ? 923 GLN A N 1 ATOM 7366 C CA . GLN A 1 923 ? 44.918 61.235 -21.796 1.00 7.64 ? 923 GLN A CA 1 ATOM 7367 C C . GLN A 1 923 ? 45.418 62.626 -22.215 1.00 8.07 ? 923 GLN A C 1 ATOM 7368 O O . GLN A 1 923 ? 46.250 63.201 -21.542 1.00 8.53 ? 923 GLN A O 1 ATOM 7369 C CB . GLN A 1 923 ? 45.734 60.149 -22.513 1.00 8.10 ? 923 GLN A CB 1 ATOM 7370 C CG . GLN A 1 923 ? 45.481 58.763 -21.961 1.00 9.07 ? 923 GLN A CG 1 ATOM 7371 C CD . GLN A 1 923 ? 46.413 57.760 -22.567 1.00 9.45 ? 923 GLN A CD 1 ATOM 7372 O OE1 . GLN A 1 923 ? 46.564 57.706 -23.796 1.00 10.93 ? 923 GLN A OE1 1 ATOM 7373 N NE2 . GLN A 1 923 ? 47.055 56.949 -21.703 1.00 9.62 ? 923 GLN A NE2 1 ATOM 7374 N N . SER A 1 924 ? 44.895 63.165 -23.314 1.00 8.33 ? 924 SER A N 1 ATOM 7375 C CA . SER A 1 924 ? 45.294 64.480 -23.788 1.00 8.45 ? 924 SER A CA 1 ATOM 7376 C C . SER A 1 924 ? 44.931 65.537 -22.738 1.00 9.20 ? 924 SER A C 1 ATOM 7377 O O A SER A 1 924 ? 45.668 66.496 -22.538 0.50 10.46 ? 924 SER A O 1 ATOM 7378 O O B SER A 1 924 ? 45.488 66.673 -22.692 0.50 8.24 ? 924 SER A O 1 ATOM 7379 C CB A SER A 1 924 ? 44.588 64.808 -25.113 0.50 8.50 ? 924 SER A CB 1 ATOM 7380 C CB B SER A 1 924 ? 44.812 64.817 -25.121 0.50 7.78 ? 924 SER A CB 1 ATOM 7381 O OG A SER A 1 924 ? 43.269 65.314 -24.961 0.50 10.93 ? 924 SER A OG 1 ATOM 7382 O OG B SER A 1 924 ? 45.396 63.974 -26.099 0.50 7.60 ? 924 SER A OG 1 ATOM 7383 N N . LEU A 1 925 ? 43.823 65.340 -22.037 1.00 8.41 ? 925 LEU A N 1 ATOM 7384 C CA . LEU A 1 925 ? 43.373 66.302 -21.039 1.00 8.25 ? 925 LEU A CA 1 ATOM 7385 C C . LEU A 1 925 ? 44.123 66.142 -19.698 1.00 9.13 ? 925 LEU A C 1 ATOM 7386 O O . LEU A 1 925 ? 44.504 67.146 -19.057 1.00 10.40 ? 925 LEU A O 1 ATOM 7387 C CB . LEU A 1 925 ? 41.872 66.106 -20.740 1.00 8.12 ? 925 LEU A CB 1 ATOM 7388 C CG . LEU A 1 925 ? 40.961 66.421 -21.927 1.00 6.70 ? 925 LEU A CG 1 ATOM 7389 C CD1 . LEU A 1 925 ? 39.517 66.148 -21.482 1.00 8.52 ? 925 LEU A CD1 1 ATOM 7390 C CD2 . LEU A 1 925 ? 41.111 67.897 -22.361 1.00 9.34 ? 925 LEU A CD2 1 ATOM 7391 N N . LEU A 1 926 ? 44.325 64.881 -19.300 1.00 7.67 ? 926 LEU A N 1 ATOM 7392 C CA . LEU A 1 926 ? 44.899 64.637 -17.969 1.00 7.45 ? 926 LEU A CA 1 ATOM 7393 C C . LEU A 1 926 ? 46.381 64.610 -17.928 1.00 7.87 ? 926 LEU A C 1 ATOM 7394 O O . LEU A 1 926 ? 46.950 65.014 -16.890 1.00 8.34 ? 926 LEU A O 1 ATOM 7395 C CB . LEU A 1 926 ? 44.325 63.347 -17.340 1.00 8.58 ? 926 LEU A CB 1 ATOM 7396 C CG . LEU A 1 926 ? 42.776 63.415 -17.135 1.00 11.05 ? 926 LEU A CG 1 ATOM 7397 C CD1 . LEU A 1 926 ? 42.326 62.041 -16.561 1.00 11.32 ? 926 LEU A CD1 1 ATOM 7398 C CD2 . LEU A 1 926 ? 42.407 64.594 -16.183 1.00 13.55 ? 926 LEU A CD2 1 ATOM 7399 N N . ASP A 1 927 ? 47.005 64.139 -18.988 1.00 7.00 ? 927 ASP A N 1 ATOM 7400 C CA . ASP A 1 927 ? 48.476 64.056 -19.023 1.00 7.33 ? 927 ASP A CA 1 ATOM 7401 C C . ASP A 1 927 ? 49.052 64.596 -20.322 1.00 7.13 ? 927 ASP A C 1 ATOM 7402 O O . ASP A 1 927 ? 49.619 63.861 -21.121 1.00 7.74 ? 927 ASP A O 1 ATOM 7403 C CB . ASP A 1 927 ? 48.947 62.608 -18.730 1.00 7.99 ? 927 ASP A CB 1 ATOM 7404 C CG . ASP A 1 927 ? 48.606 62.184 -17.299 1.00 7.95 ? 927 ASP A CG 1 ATOM 7405 O OD1 . ASP A 1 927 ? 49.341 62.576 -16.346 1.00 7.92 ? 927 ASP A OD1 1 ATOM 7406 O OD2 . ASP A 1 927 ? 47.575 61.508 -17.154 1.00 9.72 ? 927 ASP A OD2 1 ATOM 7407 N N . PRO A 1 928 ? 48.879 65.893 -20.529 1.00 7.49 ? 928 PRO A N 1 ATOM 7408 C CA . PRO A 1 928 ? 49.395 66.547 -21.749 1.00 8.01 ? 928 PRO A CA 1 ATOM 7409 C C . PRO A 1 928 ? 50.921 66.568 -21.741 1.00 8.24 ? 928 PRO A C 1 ATOM 7410 O O . PRO A 1 928 ? 51.573 66.293 -20.734 1.00 8.29 ? 928 PRO A O 1 ATOM 7411 C CB . PRO A 1 928 ? 48.863 67.977 -21.626 1.00 9.53 ? 928 PRO A CB 1 ATOM 7412 C CG . PRO A 1 928 ? 48.853 68.229 -20.129 1.00 10.62 ? 928 PRO A CG 1 ATOM 7413 C CD . PRO A 1 928 ? 48.331 66.874 -19.569 1.00 9.50 ? 928 PRO A CD 1 ATOM 7414 N N . LEU A 1 929 ? 51.504 66.863 -22.875 1.00 7.67 ? 929 LEU A N 1 ATOM 7415 C CA . LEU A 1 929 ? 52.934 67.143 -22.888 1.00 7.68 ? 929 LEU A CA 1 ATOM 7416 C C . LEU A 1 929 ? 53.232 68.341 -21.981 1.00 7.80 ? 929 LEU A C 1 ATOM 7417 O O . LEU A 1 929 ? 52.476 69.299 -21.911 1.00 9.42 ? 929 LEU A O 1 ATOM 7418 C CB . LEU A 1 929 ? 53.410 67.499 -24.327 1.00 8.43 ? 929 LEU A CB 1 ATOM 7419 C CG . LEU A 1 929 ? 53.188 66.441 -25.375 1.00 8.43 ? 929 LEU A CG 1 ATOM 7420 C CD1 . LEU A 1 929 ? 53.739 67.049 -26.687 1.00 10.36 ? 929 LEU A CD1 1 ATOM 7421 C CD2 . LEU A 1 929 ? 54.005 65.156 -25.060 1.00 8.33 ? 929 LEU A CD2 1 ATOM 7422 N N . ASP A 1 930 ? 54.340 68.271 -21.263 1.00 7.54 ? 930 ASP A N 1 ATOM 7423 C CA . ASP A 1 930 ? 54.808 69.399 -20.449 1.00 7.10 ? 930 ASP A CA 1 ATOM 7424 C C . ASP A 1 930 ? 55.763 70.221 -21.307 1.00 7.55 ? 930 ASP A C 1 ATOM 7425 O O . ASP A 1 930 ? 56.522 69.682 -22.134 1.00 9.29 ? 930 ASP A O 1 ATOM 7426 C CB . ASP A 1 930 ? 55.538 68.878 -19.204 1.00 8.24 ? 930 ASP A CB 1 ATOM 7427 C CG . ASP A 1 930 ? 54.745 67.844 -18.488 1.00 8.54 ? 930 ASP A CG 1 ATOM 7428 O OD1 . ASP A 1 930 ? 53.650 68.249 -18.009 1.00 11.20 ? 930 ASP A OD1 1 ATOM 7429 O OD2 . ASP A 1 930 ? 55.164 66.663 -18.436 1.00 8.91 ? 930 ASP A OD2 1 ATOM 7430 N N . LYS A 1 931 ? 55.745 71.528 -21.126 1.00 7.57 ? 931 LYS A N 1 ATOM 7431 C CA . LYS A 1 931 ? 56.559 72.455 -21.931 1.00 7.30 ? 931 LYS A CA 1 ATOM 7432 C C . LYS A 1 931 ? 57.471 73.239 -21.061 1.00 8.03 ? 931 LYS A C 1 ATOM 7433 O O . LYS A 1 931 ? 57.030 73.841 -20.068 1.00 9.98 ? 931 LYS A O 1 ATOM 7434 C CB . LYS A 1 931 ? 55.607 73.413 -22.676 1.00 8.66 ? 931 LYS A CB 1 ATOM 7435 C CG . LYS A 1 931 ? 54.643 72.747 -23.703 1.00 11.23 ? 931 LYS A CG 1 ATOM 7436 C CD . LYS A 1 931 ? 53.706 73.789 -24.336 1.00 13.92 ? 931 LYS A CD 1 ATOM 7437 C CE . LYS A 1 931 ? 52.743 74.386 -23.326 1.00 15.65 ? 931 LYS A CE 1 ATOM 7438 N NZ . LYS A 1 931 ? 52.051 75.465 -23.937 1.00 16.11 ? 931 LYS A NZ 1 ATOM 7439 N N . PHE A 1 932 ? 58.740 73.316 -21.456 1.00 7.47 ? 932 PHE A N 1 ATOM 7440 C CA . PHE A 1 932 ? 59.777 74.026 -20.712 1.00 7.29 ? 932 PHE A CA 1 ATOM 7441 C C . PHE A 1 932 ? 60.445 75.075 -21.593 1.00 6.89 ? 932 PHE A C 1 ATOM 7442 O O . PHE A 1 932 ? 60.788 74.754 -22.719 1.00 8.79 ? 932 PHE A O 1 ATOM 7443 C CB . PHE A 1 932 ? 60.838 73.037 -20.230 1.00 8.57 ? 932 PHE A CB 1 ATOM 7444 C CG . PHE A 1 932 ? 60.326 71.959 -19.333 1.00 8.64 ? 932 PHE A CG 1 ATOM 7445 C CD1 . PHE A 1 932 ? 59.724 70.806 -19.844 1.00 8.95 ? 932 PHE A CD1 1 ATOM 7446 C CD2 . PHE A 1 932 ? 60.505 72.091 -17.955 1.00 10.16 ? 932 PHE A CD2 1 ATOM 7447 C CE1 . PHE A 1 932 ? 59.294 69.756 -19.006 1.00 8.01 ? 932 PHE A CE1 1 ATOM 7448 C CE2 . PHE A 1 932 ? 60.090 71.053 -17.080 1.00 9.96 ? 932 PHE A CE2 1 ATOM 7449 C CZ . PHE A 1 932 ? 59.487 69.892 -17.607 1.00 9.89 ? 932 PHE A CZ 1 ATOM 7450 N N . ILE A 1 933 ? 60.633 76.288 -21.106 1.00 8.19 ? 933 ILE A N 1 ATOM 7451 C CA . ILE A 1 933 ? 61.305 77.358 -21.877 1.00 8.27 ? 933 ILE A CA 1 ATOM 7452 C C . ILE A 1 933 ? 62.655 77.566 -21.198 1.00 8.35 ? 933 ILE A C 1 ATOM 7453 O O . ILE A 1 933 ? 62.719 77.855 -19.982 1.00 8.48 ? 933 ILE A O 1 ATOM 7454 C CB . ILE A 1 933 ? 60.491 78.659 -21.798 1.00 8.82 ? 933 ILE A CB 1 ATOM 7455 C CG1 . ILE A 1 933 ? 59.070 78.415 -22.343 1.00 8.75 ? 933 ILE A CG1 1 ATOM 7456 C CG2 . ILE A 1 933 ? 61.227 79.765 -22.572 1.00 8.79 ? 933 ILE A CG2 1 ATOM 7457 C CD1 . ILE A 1 933 ? 58.158 79.636 -22.146 1.00 10.09 ? 933 ILE A CD1 1 ATOM 7458 N N . PHE A 1 934 ? 63.758 77.413 -21.939 1.00 7.74 ? 934 PHE A N 1 ATOM 7459 C CA . PHE A 1 934 ? 65.074 77.618 -21.327 1.00 9.01 ? 934 PHE A CA 1 ATOM 7460 C C . PHE A 1 934 ? 65.162 79.091 -20.862 1.00 9.00 ? 934 PHE A C 1 ATOM 7461 O O . PHE A 1 934 ? 64.850 80.023 -21.610 1.00 10.54 ? 934 PHE A O 1 ATOM 7462 C CB . PHE A 1 934 ? 66.194 77.280 -22.338 1.00 10.31 ? 934 PHE A CB 1 ATOM 7463 C CG . PHE A 1 934 ? 67.569 77.291 -21.741 1.00 10.41 ? 934 PHE A CG 1 ATOM 7464 C CD1 . PHE A 1 934 ? 67.967 76.289 -20.895 1.00 10.79 ? 934 PHE A CD1 1 ATOM 7465 C CD2 . PHE A 1 934 ? 68.442 78.360 -21.989 1.00 11.85 ? 934 PHE A CD2 1 ATOM 7466 C CE1 . PHE A 1 934 ? 69.224 76.318 -20.278 1.00 13.40 ? 934 PHE A CE1 1 ATOM 7467 C CE2 . PHE A 1 934 ? 69.697 78.412 -21.391 1.00 12.85 ? 934 PHE A CE2 1 ATOM 7468 C CZ . PHE A 1 934 ? 70.097 77.396 -20.534 1.00 14.12 ? 934 PHE A CZ 1 ATOM 7469 N N . ALA A 1 935 ? 65.582 79.311 -19.611 1.00 9.74 ? 935 ALA A N 1 ATOM 7470 C CA . ALA A 1 935 ? 65.536 80.666 -19.075 1.00 11.62 ? 935 ALA A CA 1 ATOM 7471 C C . ALA A 1 935 ? 66.676 81.611 -19.503 1.00 13.80 ? 935 ALA A C 1 ATOM 7472 O O . ALA A 1 935 ? 66.428 82.829 -19.798 1.00 17.46 ? 935 ALA A O 1 ATOM 7473 C CB . ALA A 1 935 ? 65.463 80.572 -17.537 1.00 14.10 ? 935 ALA A CB 1 ATOM 7474 N N . GLU A 1 936 ? 67.883 81.098 -19.605 1.00 13.13 ? 936 GLU A N 1 ATOM 7475 C CA . GLU A 1 936 ? 69.057 81.918 -19.946 1.00 13.74 ? 936 GLU A CA 1 ATOM 7476 C C . GLU A 1 936 ? 69.162 82.119 -21.461 1.00 13.04 ? 936 GLU A C 1 ATOM 7477 O O . GLU A 1 936 ? 68.380 81.541 -22.248 1.00 13.73 ? 936 GLU A O 1 ATOM 7478 C CB . GLU A 1 936 ? 70.339 81.246 -19.445 1.00 16.35 ? 936 GLU A CB 1 ATOM 7479 C CG . GLU A 1 936 ? 70.480 80.958 -17.912 1.00 21.13 ? 936 GLU A CG 1 ATOM 7480 C CD . GLU A 1 936 ? 71.609 79.870 -17.612 1.00 23.20 ? 936 GLU A CD 1 ATOM 7481 O OE1 . GLU A 1 936 ? 71.432 78.635 -17.860 1.00 22.25 ? 936 GLU A OE1 1 ATOM 7482 O OE2 . GLU A 1 936 ? 72.720 80.244 -17.150 1.00 25.89 ? 936 GLU A OE2 1 ATOM 7483 N N . ASN A 1 937 ? 70.160 82.879 -21.890 1.00 13.19 ? 937 ASN A N 1 ATOM 7484 C CA . ASN A 1 937 ? 70.265 83.122 -23.306 1.00 12.65 ? 937 ASN A CA 1 ATOM 7485 C C . ASN A 1 937 ? 70.854 81.976 -24.101 1.00 12.46 ? 937 ASN A C 1 ATOM 7486 O O . ASN A 1 937 ? 70.465 81.768 -25.260 1.00 12.91 ? 937 ASN A O 1 ATOM 7487 C CB . ASN A 1 937 ? 71.097 84.386 -23.559 1.00 14.76 ? 937 ASN A CB 1 ATOM 7488 C CG . ASN A 1 937 ? 70.370 85.654 -23.170 1.00 17.50 ? 937 ASN A CG 1 ATOM 7489 O OD1 . ASN A 1 937 ? 69.130 85.688 -23.020 1.00 15.99 ? 937 ASN A OD1 1 ATOM 7490 N ND2 . ASN A 1 937 ? 71.149 86.730 -23.021 1.00 20.25 ? 937 ASN A ND2 1 ATOM 7491 N N . GLU A 1 938 ? 71.809 81.251 -23.508 1.00 13.07 ? 938 GLU A N 1 ATOM 7492 C CA . GLU A 1 938 ? 72.409 80.154 -24.246 1.00 15.15 ? 938 GLU A CA 1 ATOM 7493 C C . GLU A 1 938 ? 72.505 78.913 -23.380 1.00 13.56 ? 938 GLU A C 1 ATOM 7494 O O . GLU A 1 938 ? 72.940 78.978 -22.255 1.00 14.13 ? 938 GLU A O 1 ATOM 7495 C CB . GLU A 1 938 ? 73.819 80.516 -24.741 1.00 17.82 ? 938 GLU A CB 1 ATOM 7496 C CG . GLU A 1 938 ? 74.454 79.345 -25.457 1.00 23.34 ? 938 GLU A CG 1 ATOM 7497 C CD . GLU A 1 938 ? 75.695 79.696 -26.255 1.00 25.78 ? 938 GLU A CD 1 ATOM 7498 O OE1 . GLU A 1 938 ? 76.394 80.674 -25.906 1.00 29.47 ? 938 GLU A OE1 1 ATOM 7499 O OE2 . GLU A 1 938 ? 75.969 78.947 -27.229 1.00 28.82 ? 938 GLU A OE2 1 ATOM 7500 N N . TRP A 1 939 ? 72.103 77.778 -23.946 1.00 14.64 ? 939 TRP A N 1 ATOM 7501 C CA . TRP A 1 939 ? 72.181 76.512 -23.221 1.00 14.58 ? 939 TRP A CA 1 ATOM 7502 C C . TRP A 1 939 ? 73.406 75.736 -23.735 1.00 15.34 ? 939 TRP A C 1 ATOM 7503 O O . TRP A 1 939 ? 73.331 75.097 -24.773 1.00 17.08 ? 939 TRP A O 1 ATOM 7504 C CB . TRP A 1 939 ? 70.865 75.762 -23.477 1.00 13.90 ? 939 TRP A CB 1 ATOM 7505 C CG . TRP A 1 939 ? 70.756 74.377 -22.832 1.00 11.56 ? 939 TRP A CG 1 ATOM 7506 C CD1 . TRP A 1 939 ? 71.643 73.745 -21.975 1.00 11.79 ? 939 TRP A CD1 1 ATOM 7507 C CD2 . TRP A 1 939 ? 69.679 73.478 -23.035 1.00 11.43 ? 939 TRP A CD2 1 ATOM 7508 N NE1 . TRP A 1 939 ? 71.154 72.494 -21.643 1.00 10.94 ? 939 TRP A NE1 1 ATOM 7509 C CE2 . TRP A 1 939 ? 69.952 72.308 -22.290 1.00 11.35 ? 939 TRP A CE2 1 ATOM 7510 C CE3 . TRP A 1 939 ? 68.495 73.548 -23.788 1.00 10.89 ? 939 TRP A CE3 1 ATOM 7511 C CZ2 . TRP A 1 939 ? 69.089 71.217 -22.281 1.00 11.84 ? 939 TRP A CZ2 1 ATOM 7512 C CZ3 . TRP A 1 939 ? 67.626 72.476 -23.786 1.00 11.87 ? 939 TRP A CZ3 1 ATOM 7513 C CH2 . TRP A 1 939 ? 67.929 71.309 -23.036 1.00 11.23 ? 939 TRP A CH2 1 ATOM 7514 N N . ILE A 1 940 ? 74.506 75.806 -22.986 1.00 17.24 ? 940 ILE A N 1 ATOM 7515 C CA . ILE A 1 940 ? 75.713 75.101 -23.449 1.00 18.83 ? 940 ILE A CA 1 ATOM 7516 C C . ILE A 1 940 ? 75.595 73.579 -23.192 1.00 17.96 ? 940 ILE A C 1 ATOM 7517 O O . ILE A 1 940 ? 75.162 73.152 -22.130 1.00 18.58 ? 940 ILE A O 1 ATOM 7518 C CB . ILE A 1 940 ? 76.966 75.695 -22.780 1.00 20.37 ? 940 ILE A CB 1 ATOM 7519 C CG1 . ILE A 1 940 ? 77.165 77.142 -23.268 1.00 22.38 ? 940 ILE A CG1 1 ATOM 7520 C CG2 . ILE A 1 940 ? 78.200 74.832 -23.120 1.00 21.28 ? 940 ILE A CG2 1 ATOM 7521 C CD1 . ILE A 1 940 ? 77.926 78.000 -22.288 1.00 25.72 ? 940 ILE A CD1 1 ATOM 7522 N N . GLY A 1 941 ? 75.930 72.790 -24.195 1.00 17.88 ? 941 GLY A N 1 ATOM 7523 C CA . GLY A 1 941 ? 75.840 71.339 -24.030 1.00 16.78 ? 941 GLY A CA 1 ATOM 7524 C C . GLY A 1 941 ? 74.444 70.746 -24.262 1.00 16.68 ? 941 GLY A C 1 ATOM 7525 O O . GLY A 1 941 ? 74.217 69.551 -23.982 1.00 15.63 ? 941 GLY A O 1 ATOM 7526 N N . ALA A 1 942 ? 73.519 71.542 -24.799 1.00 15.66 ? 942 ALA A N 1 ATOM 7527 C CA . ALA A 1 942 ? 72.158 71.060 -25.054 1.00 16.30 ? 942 ALA A CA 1 ATOM 7528 C C . ALA A 1 942 ? 72.084 69.846 -25.954 1.00 15.91 ? 942 ALA A C 1 ATOM 7529 O O . ALA A 1 942 ? 72.794 69.756 -26.961 1.00 17.44 ? 942 ALA A O 1 ATOM 7530 C CB . ALA A 1 942 ? 71.311 72.176 -25.675 1.00 16.48 ? 942 ALA A CB 1 ATOM 7531 N N . GLN A 1 943 ? 71.213 68.902 -25.604 1.00 15.35 ? 943 GLN A N 1 ATOM 7532 C CA . GLN A 1 943 ? 70.984 67.711 -26.391 1.00 14.47 ? 943 GLN A CA 1 ATOM 7533 C C . GLN A 1 943 ? 69.561 67.737 -26.927 1.00 13.36 ? 943 GLN A C 1 ATOM 7534 O O . GLN A 1 943 ? 68.675 68.408 -26.332 1.00 14.77 ? 943 GLN A O 1 ATOM 7535 C CB . GLN A 1 943 ? 71.185 66.446 -25.553 1.00 17.14 ? 943 GLN A CB 1 ATOM 7536 C CG . GLN A 1 943 ? 72.576 66.471 -24.929 1.00 20.50 ? 943 GLN A CG 1 ATOM 7537 C CD . GLN A 1 943 ? 72.850 65.226 -24.129 1.00 22.52 ? 943 GLN A CD 1 ATOM 7538 O OE1 . GLN A 1 943 ? 71.966 64.752 -23.401 1.00 25.82 ? 943 GLN A OE1 1 ATOM 7539 N NE2 . GLN A 1 943 ? 74.083 64.687 -24.238 1.00 25.10 ? 943 GLN A NE2 1 ATOM 7540 N N . GLY A 1 944 ? 69.303 67.026 -28.013 1.00 13.27 ? 944 GLY A N 1 ATOM 7541 C CA . GLY A 1 944 ? 68.029 67.091 -28.669 1.00 13.65 ? 944 GLY A CA 1 ATOM 7542 C C . GLY A 1 944 ? 66.930 66.159 -28.253 1.00 13.05 ? 944 GLY A C 1 ATOM 7543 O O . GLY A 1 944 ? 65.741 66.390 -28.542 1.00 13.58 ? 944 GLY A O 1 ATOM 7544 N N . GLN A 1 945 ? 67.297 65.097 -27.546 1.00 12.76 ? 945 GLN A N 1 ATOM 7545 C CA . GLN A 1 945 ? 66.283 64.112 -27.199 1.00 13.12 ? 945 GLN A CA 1 ATOM 7546 C C . GLN A 1 945 ? 66.715 63.223 -26.063 1.00 13.07 ? 945 GLN A C 1 ATOM 7547 O O . GLN A 1 945 ? 67.911 63.015 -25.820 1.00 13.90 ? 945 GLN A O 1 ATOM 7548 C CB . GLN A 1 945 ? 65.988 63.265 -28.440 1.00 13.80 ? 945 GLN A CB 1 ATOM 7549 C CG . GLN A 1 945 ? 64.738 62.355 -28.399 1.00 16.30 ? 945 GLN A CG 1 ATOM 7550 C CD . GLN A 1 945 ? 64.686 61.395 -29.628 1.00 17.19 ? 945 GLN A CD 1 ATOM 7551 O OE1 . GLN A 1 945 ? 63.876 61.559 -30.542 1.00 20.49 ? 945 GLN A OE1 1 ATOM 7552 N NE2 . GLN A 1 945 ? 65.537 60.407 -29.623 1.00 18.70 ? 945 GLN A NE2 1 ATOM 7553 N N . PHE A 1 946 ? 65.724 62.747 -25.306 1.00 10.94 ? 946 PHE A N 1 ATOM 7554 C CA . PHE A 1 946 ? 65.979 61.747 -24.243 1.00 10.46 ? 946 PHE A CA 1 ATOM 7555 C C . PHE A 1 946 ? 64.854 60.748 -24.362 1.00 10.35 ? 946 PHE A C 1 ATOM 7556 O O . PHE A 1 946 ? 63.707 61.094 -24.574 1.00 10.07 ? 946 PHE A O 1 ATOM 7557 C CB . PHE A 1 946 ? 65.949 62.398 -22.850 1.00 10.91 ? 946 PHE A CB 1 ATOM 7558 C CG . PHE A 1 946 ? 65.830 61.392 -21.732 1.00 10.94 ? 946 PHE A CG 1 ATOM 7559 C CD1 . PHE A 1 946 ? 66.891 60.560 -21.403 1.00 11.82 ? 946 PHE A CD1 1 ATOM 7560 C CD2 . PHE A 1 946 ? 64.604 61.231 -21.069 1.00 11.35 ? 946 PHE A CD2 1 ATOM 7561 C CE1 . PHE A 1 946 ? 66.739 59.545 -20.408 1.00 12.68 ? 946 PHE A CE1 1 ATOM 7562 C CE2 . PHE A 1 946 ? 64.436 60.247 -20.101 1.00 12.48 ? 946 PHE A CE2 1 ATOM 7563 C CZ . PHE A 1 946 ? 65.466 59.409 -19.762 1.00 12.45 ? 946 PHE A CZ 1 ATOM 7564 N N . GLY A 1 947 ? 65.188 59.469 -24.207 1.00 10.94 ? 947 GLY A N 1 ATOM 7565 C CA . GLY A 1 947 ? 64.212 58.404 -24.256 1.00 12.27 ? 947 GLY A CA 1 ATOM 7566 C C . GLY A 1 947 ? 63.872 57.820 -25.600 1.00 11.88 ? 947 GLY A C 1 ATOM 7567 O O . GLY A 1 947 ? 62.936 57.043 -25.684 1.00 13.00 ? 947 GLY A O 1 ATOM 7568 N N . GLY A 1 948 ? 64.672 58.126 -26.641 1.00 13.45 ? 948 GLY A N 1 ATOM 7569 C CA . GLY A 1 948 ? 64.394 57.590 -27.960 1.00 15.25 ? 948 GLY A CA 1 ATOM 7570 C C . GLY A 1 948 ? 64.391 56.063 -28.003 1.00 16.17 ? 948 GLY A C 1 ATOM 7571 O O . GLY A 1 948 ? 63.750 55.476 -28.897 1.00 18.92 ? 948 GLY A O 1 ATOM 7572 N N . ASP A 1 949 ? 65.089 55.436 -27.048 1.00 17.12 ? 949 ASP A N 1 ATOM 7573 C CA . ASP A 1 949 ? 65.167 53.974 -26.952 1.00 18.72 ? 949 ASP A CA 1 ATOM 7574 C C . ASP A 1 949 ? 64.161 53.361 -25.972 1.00 18.22 ? 949 ASP A C 1 ATOM 7575 O O . ASP A 1 949 ? 64.160 52.131 -25.714 1.00 18.35 ? 949 ASP A O 1 ATOM 7576 C CB . ASP A 1 949 ? 66.614 53.541 -26.580 1.00 21.81 ? 949 ASP A CB 1 ATOM 7577 C CG . ASP A 1 949 ? 67.090 54.061 -25.202 1.00 25.38 ? 949 ASP A CG 1 ATOM 7578 O OD1 . ASP A 1 949 ? 66.579 55.082 -24.631 1.00 26.86 ? 949 ASP A OD1 1 ATOM 7579 O OD2 . ASP A 1 949 ? 68.048 53.427 -24.663 1.00 28.96 ? 949 ASP A OD2 1 ATOM 7580 N N . HIS A 1 950 ? 63.306 54.200 -25.380 1.00 16.50 ? 950 HIS A N 1 ATOM 7581 C CA . HIS A 1 950 ? 62.295 53.653 -24.478 1.00 14.15 ? 950 HIS A CA 1 ATOM 7582 C C . HIS A 1 950 ? 61.208 52.923 -25.305 1.00 14.17 ? 950 HIS A C 1 ATOM 7583 O O . HIS A 1 950 ? 60.814 53.378 -26.376 1.00 14.60 ? 950 HIS A O 1 ATOM 7584 C CB . HIS A 1 950 ? 61.589 54.779 -23.751 1.00 12.16 ? 950 HIS A CB 1 ATOM 7585 C CG . HIS A 1 950 ? 62.414 55.554 -22.786 1.00 11.48 ? 950 HIS A CG 1 ATOM 7586 N ND1 . HIS A 1 950 ? 63.663 55.213 -22.290 1.00 13.65 ? 950 HIS A ND1 1 ATOM 7587 C CD2 . HIS A 1 950 ? 62.070 56.702 -22.165 1.00 8.80 ? 950 HIS A CD2 1 ATOM 7588 C CE1 . HIS A 1 950 ? 64.039 56.129 -21.406 1.00 10.70 ? 950 HIS A CE1 1 ATOM 7589 N NE2 . HIS A 1 950 ? 63.080 57.041 -21.321 1.00 13.74 ? 950 HIS A NE2 1 ATOM 7590 N N . PRO A 1 951 ? 60.723 51.762 -24.839 1.00 13.91 ? 951 PRO A N 1 ATOM 7591 C CA . PRO A 1 951 ? 59.689 51.031 -25.588 1.00 13.93 ? 951 PRO A CA 1 ATOM 7592 C C . PRO A 1 951 ? 58.411 51.830 -25.701 1.00 13.93 ? 951 PRO A C 1 ATOM 7593 O O . PRO A 1 951 ? 57.996 52.483 -24.719 1.00 13.58 ? 951 PRO A O 1 ATOM 7594 C CB . PRO A 1 951 ? 59.443 49.749 -24.746 1.00 15.35 ? 951 PRO A CB 1 ATOM 7595 C CG . PRO A 1 951 ? 60.706 49.577 -24.019 1.00 16.24 ? 951 PRO A CG 1 ATOM 7596 C CD . PRO A 1 951 ? 61.191 50.998 -23.671 1.00 16.11 ? 951 PRO A CD 1 ATOM 7597 N N . SER A 1 952 ? 57.761 51.765 -26.849 1.00 12.73 ? 952 SER A N 1 ATOM 7598 C CA . SER A 1 952 ? 56.526 52.478 -27.068 1.00 12.62 ? 952 SER A CA 1 ATOM 7599 C C . SER A 1 952 ? 55.444 51.415 -26.886 1.00 12.83 ? 952 SER A C 1 ATOM 7600 O O . SER A 1 952 ? 55.154 50.595 -27.808 1.00 13.20 ? 952 SER A O 1 ATOM 7601 C CB . SER A 1 952 ? 56.508 53.114 -28.474 1.00 12.53 ? 952 SER A CB 1 ATOM 7602 O OG . SER A 1 952 ? 55.408 53.999 -28.624 1.00 14.15 ? 952 SER A OG 1 ATOM 7603 N N . ALA A 1 953 ? 54.842 51.398 -25.694 1.00 12.17 ? 953 ALA A N 1 ATOM 7604 C CA . ALA A 1 953 ? 53.875 50.375 -25.319 1.00 11.48 ? 953 ALA A CA 1 ATOM 7605 C C . ALA A 1 953 ? 52.516 50.502 -25.937 1.00 11.44 ? 953 ALA A C 1 ATOM 7606 O O . ALA A 1 953 ? 52.117 51.549 -26.406 1.00 12.02 ? 953 ALA A O 1 ATOM 7607 C CB . ALA A 1 953 ? 53.737 50.344 -23.766 1.00 12.64 ? 953 ALA A CB 1 ATOM 7608 N N . ARG A 1 954 ? 51.789 49.391 -25.937 1.00 11.53 ? 954 ARG A N 1 ATOM 7609 C CA . ARG A 1 954 ? 50.447 49.318 -26.444 1.00 12.30 ? 954 ARG A CA 1 ATOM 7610 C C . ARG A 1 954 ? 49.619 50.463 -25.818 1.00 11.26 ? 954 ARG A C 1 ATOM 7611 O O . ARG A 1 954 ? 49.758 50.778 -24.626 1.00 10.57 ? 954 ARG A O 1 ATOM 7612 C CB . ARG A 1 954 ? 49.898 47.918 -26.114 1.00 14.66 ? 954 ARG A CB 1 ATOM 7613 C CG . ARG A 1 954 ? 49.906 47.610 -24.621 1.00 18.88 ? 954 ARG A CG 1 ATOM 7614 C CD . ARG A 1 954 ? 49.319 46.218 -24.285 1.00 22.87 ? 954 ARG A CD 1 ATOM 7615 N NE . ARG A 1 954 ? 50.194 45.097 -24.643 1.00 27.37 ? 954 ARG A NE 1 ATOM 7616 C CZ . ARG A 1 954 ? 49.853 44.158 -25.519 1.00 29.85 ? 954 ARG A CZ 1 ATOM 7617 N NH1 . ARG A 1 954 ? 48.661 44.231 -26.130 1.00 30.98 ? 954 ARG A NH1 1 ATOM 7618 N NH2 . ARG A 1 954 ? 50.673 43.131 -25.759 1.00 31.57 ? 954 ARG A NH2 1 ATOM 7619 N N . GLU A 1 955 ? 48.698 50.996 -26.607 1.00 10.80 ? 955 GLU A N 1 ATOM 7620 C CA . GLU A 1 955 ? 47.933 52.175 -26.234 1.00 11.66 ? 955 GLU A CA 1 ATOM 7621 C C . GLU A 1 955 ? 47.106 52.054 -24.971 1.00 10.42 ? 955 GLU A C 1 ATOM 7622 O O . GLU A 1 955 ? 46.819 53.086 -24.326 1.00 11.70 ? 955 GLU A O 1 ATOM 7623 C CB . GLU A 1 955 ? 47.041 52.628 -27.422 1.00 13.37 ? 955 GLU A CB 1 ATOM 7624 C CG . GLU A 1 955 ? 45.951 51.629 -27.779 1.00 15.64 ? 955 GLU A CG 1 ATOM 7625 C CD . GLU A 1 955 ? 45.073 52.093 -28.898 1.00 17.76 ? 955 GLU A CD 1 ATOM 7626 O OE1 . GLU A 1 955 ? 44.938 53.311 -29.113 1.00 22.20 ? 955 GLU A OE1 1 ATOM 7627 O OE2 . GLU A 1 955 ? 44.488 51.209 -29.556 1.00 21.28 ? 955 GLU A OE2 1 ATOM 7628 N N . ASP A 1 956 ? 46.704 50.841 -24.627 1.00 9.53 ? 956 ASP A N 1 ATOM 7629 C CA . ASP A 1 956 ? 45.902 50.673 -23.419 1.00 10.03 ? 956 ASP A CA 1 ATOM 7630 C C . ASP A 1 956 ? 46.738 50.560 -22.152 1.00 8.67 ? 956 ASP A C 1 ATOM 7631 O O . ASP A 1 956 ? 46.156 50.479 -21.085 1.00 11.19 ? 956 ASP A O 1 ATOM 7632 C CB . ASP A 1 956 ? 44.910 49.500 -23.552 1.00 11.20 ? 956 ASP A CB 1 ATOM 7633 C CG . ASP A 1 956 ? 45.563 48.191 -23.891 1.00 12.72 ? 956 ASP A CG 1 ATOM 7634 O OD1 . ASP A 1 956 ? 46.794 48.137 -24.097 1.00 16.31 ? 956 ASP A OD1 1 ATOM 7635 O OD2 . ASP A 1 956 ? 44.792 47.191 -23.948 1.00 14.07 ? 956 ASP A OD2 1 ATOM 7636 N N . LEU A 1 957 ? 48.051 50.570 -22.245 1.00 9.23 ? 957 LEU A N 1 ATOM 7637 C CA . LEU A 1 957 ? 48.904 50.433 -21.064 1.00 9.00 ? 957 LEU A CA 1 ATOM 7638 C C . LEU A 1 957 ? 49.489 51.781 -20.671 1.00 8.74 ? 957 LEU A C 1 ATOM 7639 O O . LEU A 1 957 ? 49.921 52.562 -21.521 1.00 9.93 ? 957 LEU A O 1 ATOM 7640 C CB . LEU A 1 957 ? 50.064 49.473 -21.422 1.00 10.48 ? 957 LEU A CB 1 ATOM 7641 C CG . LEU A 1 957 ? 50.934 49.012 -20.250 1.00 12.82 ? 957 LEU A CG 1 ATOM 7642 C CD1 . LEU A 1 957 ? 50.102 48.276 -19.208 1.00 16.05 ? 957 LEU A CD1 1 ATOM 7643 C CD2 . LEU A 1 957 ? 52.020 48.077 -20.789 1.00 14.01 ? 957 LEU A CD2 1 ATOM 7644 N N . ASP A 1 958 ? 49.518 52.059 -19.368 1.00 8.53 ? 958 ASP A N 1 ATOM 7645 C CA . ASP A 1 958 ? 50.171 53.278 -18.863 1.00 7.53 ? 958 ASP A CA 1 ATOM 7646 C C . ASP A 1 958 ? 51.081 52.952 -17.699 1.00 7.10 ? 958 ASP A C 1 ATOM 7647 O O . ASP A 1 958 ? 50.835 51.983 -16.945 1.00 8.15 ? 958 ASP A O 1 ATOM 7648 C CB . ASP A 1 958 ? 49.079 54.295 -18.393 1.00 8.53 ? 958 ASP A CB 1 ATOM 7649 C CG . ASP A 1 958 ? 49.634 55.694 -18.205 1.00 8.95 ? 958 ASP A CG 1 ATOM 7650 O OD1 . ASP A 1 958 ? 50.742 55.995 -18.673 1.00 8.91 ? 958 ASP A OD1 1 ATOM 7651 O OD2 . ASP A 1 958 ? 48.906 56.484 -17.562 1.00 9.12 ? 958 ASP A OD2 1 ATOM 7652 N N . VAL A 1 959 ? 52.159 53.753 -17.588 1.00 7.42 ? 959 VAL A N 1 ATOM 7653 C CA . VAL A 1 959 ? 53.034 53.717 -16.418 1.00 7.99 ? 959 VAL A CA 1 ATOM 7654 C C . VAL A 1 959 ? 52.434 54.866 -15.581 1.00 6.83 ? 959 VAL A C 1 ATOM 7655 O O . VAL A 1 959 ? 52.846 56.040 -15.694 1.00 8.31 ? 959 VAL A O 1 ATOM 7656 C CB . VAL A 1 959 ? 54.485 53.966 -16.781 1.00 8.43 ? 959 VAL A CB 1 ATOM 7657 C CG1 . VAL A 1 959 ? 55.333 54.098 -15.462 1.00 8.38 ? 959 VAL A CG1 1 ATOM 7658 C CG2 . VAL A 1 959 ? 55.020 52.729 -17.611 1.00 10.04 ? 959 VAL A CG2 1 ATOM 7659 N N . SER A 1 960 ? 51.473 54.526 -14.722 1.00 7.67 ? 960 SER A N 1 ATOM 7660 C CA . SER A 1 960 ? 50.772 55.528 -13.907 1.00 7.58 ? 960 SER A CA 1 ATOM 7661 C C . SER A 1 960 ? 51.666 56.223 -12.924 1.00 7.64 ? 960 SER A C 1 ATOM 7662 O O . SER A 1 960 ? 51.501 57.442 -12.668 1.00 8.79 ? 960 SER A O 1 ATOM 7663 C CB . SER A 1 960 ? 49.650 54.868 -13.126 1.00 8.33 ? 960 SER A CB 1 ATOM 7664 O OG . SER A 1 960 ? 48.826 54.052 -13.978 1.00 10.14 ? 960 SER A OG 1 ATOM 7665 N N . VAL A 1 961 ? 52.638 55.452 -12.411 1.00 7.72 ? 961 VAL A N 1 ATOM 7666 C CA . VAL A 1 961 ? 53.620 55.987 -11.436 1.00 7.98 ? 961 VAL A CA 1 ATOM 7667 C C . VAL A 1 961 ? 55.006 55.425 -11.759 1.00 7.13 ? 961 VAL A C 1 ATOM 7668 O O . VAL A 1 961 ? 55.154 54.207 -12.015 1.00 7.15 ? 961 VAL A O 1 ATOM 7669 C CB . VAL A 1 961 ? 53.293 55.511 -9.986 1.00 8.11 ? 961 VAL A CB 1 ATOM 7670 C CG1 . VAL A 1 961 ? 54.416 55.954 -9.005 1.00 10.04 ? 961 VAL A CG1 1 ATOM 7671 C CG2 . VAL A 1 961 ? 51.934 56.130 -9.560 1.00 10.18 ? 961 VAL A CG2 1 ATOM 7672 N N . MET A 1 962 ? 56.007 56.310 -11.745 1.00 7.89 ? 962 MET A N 1 ATOM 7673 C CA . MET A 1 962 ? 57.411 55.897 -11.738 1.00 7.64 ? 962 MET A CA 1 ATOM 7674 C C . MET A 1 962 ? 57.977 56.713 -10.588 1.00 7.38 ? 962 MET A C 1 ATOM 7675 O O . MET A 1 962 ? 57.907 57.955 -10.560 1.00 7.90 ? 962 MET A O 1 ATOM 7676 C CB . MET A 1 962 ? 58.132 56.246 -13.044 1.00 8.17 ? 962 MET A CB 1 ATOM 7677 C CG . MET A 1 962 ? 59.648 55.872 -12.950 1.00 7.75 ? 962 MET A CG 1 ATOM 7678 S SD . MET A 1 962 ? 60.378 56.187 -14.581 1.00 9.77 ? 962 MET A SD 1 ATOM 7679 C CE . MET A 1 962 ? 62.123 55.714 -14.288 1.00 9.72 ? 962 MET A CE 1 ATOM 7680 N N . ARG A 1 963 ? 58.544 56.012 -9.588 1.00 8.04 ? 963 ARG A N 1 ATOM 7681 C CA . ARG A 1 963 ? 59.061 56.663 -8.396 1.00 8.07 ? 963 ARG A CA 1 ATOM 7682 C C . ARG A 1 963 ? 60.313 55.999 -7.858 1.00 8.04 ? 963 ARG A C 1 ATOM 7683 O O . ARG A 1 963 ? 60.252 54.817 -7.539 1.00 8.30 ? 963 ARG A O 1 ATOM 7684 C CB . ARG A 1 963 ? 57.988 56.594 -7.292 1.00 8.30 ? 963 ARG A CB 1 ATOM 7685 C CG . ARG A 1 963 ? 58.443 57.262 -5.954 1.00 8.40 ? 963 ARG A CG 1 ATOM 7686 C CD . ARG A 1 963 ? 57.381 57.088 -4.820 1.00 8.88 ? 963 ARG A CD 1 ATOM 7687 N NE . ARG A 1 963 ? 56.166 57.817 -5.226 1.00 8.62 ? 963 ARG A NE 1 ATOM 7688 C CZ . ARG A 1 963 ? 54.940 57.298 -5.161 1.00 8.45 ? 963 ARG A CZ 1 ATOM 7689 N NH1 . ARG A 1 963 ? 54.665 56.077 -4.646 1.00 8.81 ? 963 ARG A NH1 1 ATOM 7690 N NH2 . ARG A 1 963 ? 53.986 57.949 -5.804 1.00 8.81 ? 963 ARG A NH2 1 ATOM 7691 N N . ARG A 1 964 ? 61.425 56.722 -7.802 1.00 8.63 ? 964 ARG A N 1 ATOM 7692 C CA . ARG A 1 964 ? 62.619 56.132 -7.157 1.00 8.69 ? 964 ARG A CA 1 ATOM 7693 C C . ARG A 1 964 ? 62.297 56.084 -5.650 1.00 9.06 ? 964 ARG A C 1 ATOM 7694 O O . ARG A 1 964 ? 61.866 57.055 -5.055 1.00 9.10 ? 964 ARG A O 1 ATOM 7695 C CB . ARG A 1 964 ? 63.813 57.050 -7.445 1.00 8.17 ? 964 ARG A CB 1 ATOM 7696 C CG . ARG A 1 964 ? 65.097 56.421 -6.843 1.00 8.81 ? 964 ARG A CG 1 ATOM 7697 C CD . ARG A 1 964 ? 66.410 57.053 -7.341 1.00 9.76 ? 964 ARG A CD 1 ATOM 7698 N NE . ARG A 1 964 ? 66.588 56.870 -8.785 1.00 10.62 ? 964 ARG A NE 1 ATOM 7699 C CZ . ARG A 1 964 ? 67.471 56.062 -9.355 1.00 11.43 ? 964 ARG A CZ 1 ATOM 7700 N NH1 . ARG A 1 964 ? 68.286 55.318 -8.585 1.00 14.38 ? 964 ARG A NH1 1 ATOM 7701 N NH2 . ARG A 1 964 ? 67.585 56.016 -10.695 1.00 12.39 ? 964 ARG A NH2 1 ATOM 7702 N N . LEU A 1 965 ? 62.592 54.920 -5.068 1.00 9.41 ? 965 LEU A N 1 ATOM 7703 C CA . LEU A 1 965 ? 62.216 54.651 -3.681 1.00 9.54 ? 965 LEU A CA 1 ATOM 7704 C C . LEU A 1 965 ? 63.374 54.770 -2.695 1.00 10.20 ? 965 LEU A C 1 ATOM 7705 O O . LEU A 1 965 ? 63.157 54.699 -1.483 1.00 11.91 ? 965 LEU A O 1 ATOM 7706 C CB . LEU A 1 965 ? 61.653 53.237 -3.578 1.00 10.96 ? 965 LEU A CB 1 ATOM 7707 C CG . LEU A 1 965 ? 60.412 52.950 -4.458 1.00 9.72 ? 965 LEU A CG 1 ATOM 7708 C CD1 . LEU A 1 965 ? 60.013 51.455 -4.434 1.00 11.47 ? 965 LEU A CD1 1 ATOM 7709 C CD2 . LEU A 1 965 ? 59.197 53.806 -3.990 1.00 11.31 ? 965 LEU A CD2 1 ATOM 7710 N N . THR A 1 966 ? 64.578 54.941 -3.234 1.00 9.93 ? 966 THR A N 1 ATOM 7711 C CA . THR A 1 966 ? 65.792 55.041 -2.400 1.00 10.54 ? 966 THR A CA 1 ATOM 7712 C C . THR A 1 966 ? 66.492 56.355 -2.573 1.00 10.06 ? 966 THR A C 1 ATOM 7713 O O . THR A 1 966 ? 66.460 56.921 -3.686 1.00 10.52 ? 966 THR A O 1 ATOM 7714 C CB . THR A 1 966 ? 66.793 53.939 -2.817 1.00 10.96 ? 966 THR A CB 1 ATOM 7715 O OG1 . THR A 1 966 ? 66.837 53.861 -4.234 1.00 11.35 ? 966 THR A OG1 1 ATOM 7716 C CG2 . THR A 1 966 ? 66.371 52.568 -2.258 1.00 12.28 ? 966 THR A CG2 1 ATOM 7717 N N . LYS A 1 967 ? 67.143 56.832 -1.508 1.00 11.63 ? 967 LYS A N 1 ATOM 7718 C CA . LYS A 1 967 ? 67.988 58.028 -1.536 1.00 12.03 ? 967 LYS A CA 1 ATOM 7719 C C . LYS A 1 967 ? 69.380 57.584 -2.032 1.00 11.87 ? 967 LYS A C 1 ATOM 7720 O O . LYS A 1 967 ? 69.644 56.404 -2.202 1.00 11.54 ? 967 LYS A O 1 ATOM 7721 C CB . LYS A 1 967 ? 68.052 58.668 -0.152 1.00 13.69 ? 967 LYS A CB 1 ATOM 7722 C CG . LYS A 1 967 ? 66.663 59.243 0.302 1.00 16.62 ? 967 LYS A CG 1 ATOM 7723 C CD . LYS A 1 967 ? 66.812 59.989 1.605 1.00 19.58 ? 967 LYS A CD 1 ATOM 7724 C CE . LYS A 1 967 ? 65.457 60.639 2.012 1.00 23.89 ? 967 LYS A CE 1 ATOM 7725 N NZ . LYS A 1 967 ? 65.745 61.605 3.146 1.00 28.36 ? 967 LYS A NZ 1 ATOM 7726 N N . SER A 1 968 ? 70.197 58.594 -2.344 1.00 13.25 ? 968 SER A N 1 ATOM 7727 C CA . SER A 1 968 ? 71.495 58.330 -2.979 1.00 15.36 ? 968 SER A CA 1 ATOM 7728 C C . SER A 1 968 ? 72.469 57.477 -2.199 1.00 16.55 ? 968 SER A C 1 ATOM 7729 O O . SER A 1 968 ? 73.273 56.777 -2.832 1.00 18.74 ? 968 SER A O 1 ATOM 7730 C CB . SER A 1 968 ? 72.168 59.644 -3.400 1.00 16.55 ? 968 SER A CB 1 ATOM 7731 O OG . SER A 1 968 ? 72.413 60.482 -2.304 1.00 21.42 ? 968 SER A OG 1 ATOM 7732 N N . SER A 1 969 ? 72.330 57.473 -0.881 1.00 17.14 ? 969 SER A N 1 ATOM 7733 C CA . SER A 1 969 ? 73.257 56.666 -0.059 1.00 18.57 ? 969 SER A CA 1 ATOM 7734 C C . SER A 1 969 ? 72.998 55.159 -0.107 1.00 18.05 ? 969 SER A C 1 ATOM 7735 O O . SER A 1 969 ? 73.829 54.370 0.340 1.00 18.60 ? 969 SER A O 1 ATOM 7736 C CB . SER A 1 969 ? 73.246 57.149 1.376 1.00 21.45 ? 969 SER A CB 1 ATOM 7737 O OG . SER A 1 969 ? 71.964 56.939 1.951 1.00 26.26 ? 969 SER A OG 1 ATOM 7738 N N . ALA A 1 970 ? 71.852 54.708 -0.617 1.00 15.71 ? 970 ALA A N 1 ATOM 7739 C CA . ALA A 1 970 ? 71.602 53.282 -0.749 1.00 14.87 ? 970 ALA A CA 1 ATOM 7740 C C . ALA A 1 970 ? 72.457 52.580 -1.786 1.00 16.12 ? 970 ALA A C 1 ATOM 7741 O O . ALA A 1 970 ? 72.449 52.921 -2.972 1.00 16.18 ? 970 ALA A O 1 ATOM 7742 C CB . ALA A 1 970 ? 70.103 52.987 -1.082 1.00 14.68 ? 970 ALA A CB 1 ATOM 7743 N N . LYS A 1 971 ? 73.181 51.546 -1.360 1.00 17.65 ? 971 LYS A N 1 ATOM 7744 C CA . LYS A 1 971 ? 74.005 50.773 -2.273 1.00 19.68 ? 971 LYS A CA 1 ATOM 7745 C C . LYS A 1 971 ? 73.121 50.150 -3.364 1.00 18.63 ? 971 LYS A C 1 ATOM 7746 O O . LYS A 1 971 ? 73.508 50.138 -4.509 1.00 20.38 ? 971 LYS A O 1 ATOM 7747 C CB . LYS A 1 971 ? 74.731 49.655 -1.495 1.00 21.69 ? 971 LYS A CB 1 ATOM 7748 C CG . LYS A 1 971 ? 75.767 48.883 -2.315 1.00 26.65 ? 971 LYS A CG 1 ATOM 7749 C CD . LYS A 1 971 ? 76.581 47.940 -1.409 1.00 29.16 ? 971 LYS A CD 1 ATOM 7750 C CE . LYS A 1 971 ? 76.621 48.443 0.035 1.00 31.51 ? 971 LYS A CE 1 ATOM 7751 N NZ . LYS A 1 971 ? 77.150 49.823 0.193 1.00 33.05 ? 971 LYS A NZ 1 ATOM 7752 N N . THR A 1 972 ? 71.938 49.635 -3.008 1.00 17.56 ? 972 THR A N 1 ATOM 7753 C CA . THR A 1 972 ? 71.058 49.039 -4.013 1.00 16.92 ? 972 THR A CA 1 ATOM 7754 C C . THR A 1 972 ? 69.902 50.012 -4.246 1.00 15.66 ? 972 THR A C 1 ATOM 7755 O O . THR A 1 972 ? 69.073 50.252 -3.368 1.00 15.74 ? 972 THR A O 1 ATOM 7756 C CB . THR A 1 972 ? 70.498 47.664 -3.567 1.00 17.57 ? 972 THR A CB 1 ATOM 7757 O OG1 . THR A 1 972 ? 71.608 46.767 -3.368 1.00 18.94 ? 972 THR A OG1 1 ATOM 7758 C CG2 . THR A 1 972 ? 69.612 47.032 -4.665 1.00 19.05 ? 972 THR A CG2 1 ATOM 7759 N N . GLN A 1 973 ? 69.889 50.615 -5.422 1.00 13.77 ? 973 GLN A N 1 ATOM 7760 C CA . GLN A 1 973 ? 68.813 51.583 -5.719 1.00 12.93 ? 973 GLN A CA 1 ATOM 7761 C C . GLN A 1 973 ? 67.552 50.825 -6.092 1.00 12.78 ? 973 GLN A C 1 ATOM 7762 O O . GLN A 1 973 ? 67.585 49.760 -6.689 1.00 13.35 ? 973 GLN A O 1 ATOM 7763 C CB . GLN A 1 973 ? 69.279 52.444 -6.866 1.00 12.12 ? 973 GLN A CB 1 ATOM 7764 C CG . GLN A 1 973 ? 70.369 53.460 -6.443 1.00 12.92 ? 973 GLN A CG 1 ATOM 7765 C CD . GLN A 1 973 ? 69.923 54.450 -5.411 1.00 13.26 ? 973 GLN A CD 1 ATOM 7766 O OE1 . GLN A 1 973 ? 70.533 54.636 -4.334 1.00 14.54 ? 973 GLN A OE1 1 ATOM 7767 N NE2 . GLN A 1 973 ? 68.813 55.138 -5.722 1.00 10.98 ? 973 GLN A NE2 1 ATOM 7768 N N . ARG A 1 974 ? 66.396 51.421 -5.758 1.00 11.85 ? 974 ARG A N 1 ATOM 7769 C CA . ARG A 1 974 ? 65.127 50.777 -6.087 1.00 11.95 ? 974 ARG A CA 1 ATOM 7770 C C . ARG A 1 974 ? 64.176 51.765 -6.742 1.00 10.07 ? 974 ARG A C 1 ATOM 7771 O O . ARG A 1 974 ? 64.053 52.896 -6.280 1.00 10.83 ? 974 ARG A O 1 ATOM 7772 C CB . ARG A 1 974 ? 64.460 50.238 -4.842 1.00 12.02 ? 974 ARG A CB 1 ATOM 7773 C CG . ARG A 1 974 ? 65.321 49.168 -4.067 1.00 13.16 ? 974 ARG A CG 1 ATOM 7774 C CD . ARG A 1 974 ? 64.749 48.948 -2.619 1.00 16.16 ? 974 ARG A CD 1 ATOM 7775 N NE . ARG A 1 974 ? 63.494 48.202 -2.660 1.00 20.13 ? 974 ARG A NE 1 ATOM 7776 C CZ . ARG A 1 974 ? 62.331 48.608 -2.167 1.00 19.67 ? 974 ARG A CZ 1 ATOM 7777 N NH1 . ARG A 1 974 ? 62.195 49.788 -1.554 1.00 20.17 ? 974 ARG A NH1 1 ATOM 7778 N NH2 . ARG A 1 974 ? 61.287 47.819 -2.332 1.00 18.89 ? 974 ARG A NH2 1 ATOM 7779 N N . VAL A 1 975 ? 63.537 51.311 -7.798 1.00 10.00 ? 975 VAL A N 1 ATOM 7780 C CA . VAL A 1 975 ? 62.594 52.200 -8.496 1.00 10.43 ? 975 VAL A CA 1 ATOM 7781 C C . VAL A 1 975 ? 61.283 51.435 -8.606 1.00 10.38 ? 975 VAL A C 1 ATOM 7782 O O . VAL A 1 975 ? 61.223 50.271 -9.092 1.00 10.27 ? 975 VAL A O 1 ATOM 7783 C CB . VAL A 1 975 ? 63.090 52.520 -9.912 1.00 10.15 ? 975 VAL A CB 1 ATOM 7784 C CG1 . VAL A 1 975 ? 62.060 53.438 -10.633 1.00 11.57 ? 975 VAL A CG1 1 ATOM 7785 C CG2 . VAL A 1 975 ? 64.475 53.275 -9.803 1.00 13.81 ? 975 VAL A CG2 1 ATOM 7786 N N . GLY A 1 976 ? 60.193 52.119 -8.212 1.00 9.39 ? 976 GLY A N 1 ATOM 7787 C CA . GLY A 1 976 ? 58.851 51.539 -8.263 1.00 9.57 ? 976 GLY A CA 1 ATOM 7788 C C . GLY A 1 976 ? 58.041 52.024 -9.447 1.00 8.51 ? 976 GLY A C 1 ATOM 7789 O O . GLY A 1 976 ? 58.128 53.200 -9.815 1.00 8.52 ? 976 GLY A O 1 ATOM 7790 N N . TYR A 1 977 ? 57.267 51.126 -10.012 1.00 8.46 ? 977 TYR A N 1 ATOM 7791 C CA . TYR A 1 977 ? 56.390 51.431 -11.129 1.00 7.94 ? 977 TYR A CA 1 ATOM 7792 C C . TYR A 1 977 ? 54.988 50.935 -10.847 1.00 8.48 ? 977 TYR A C 1 ATOM 7793 O O . TYR A 1 977 ? 54.819 49.823 -10.316 1.00 9.01 ? 977 TYR A O 1 ATOM 7794 C CB . TYR A 1 977 ? 56.860 50.718 -12.405 1.00 9.23 ? 977 TYR A CB 1 ATOM 7795 C CG . TYR A 1 977 ? 58.251 51.072 -12.807 1.00 8.98 ? 977 TYR A CG 1 ATOM 7796 C CD1 . TYR A 1 977 ? 59.334 50.343 -12.324 1.00 9.02 ? 977 TYR A CD1 1 ATOM 7797 C CD2 . TYR A 1 977 ? 58.471 52.134 -13.665 1.00 8.80 ? 977 TYR A CD2 1 ATOM 7798 C CE1 . TYR A 1 977 ? 60.626 50.682 -12.712 1.00 10.18 ? 977 TYR A CE1 1 ATOM 7799 C CE2 . TYR A 1 977 ? 59.739 52.514 -14.057 1.00 9.58 ? 977 TYR A CE2 1 ATOM 7800 C CZ . TYR A 1 977 ? 60.811 51.776 -13.578 1.00 9.17 ? 977 TYR A CZ 1 ATOM 7801 O OH . TYR A 1 977 ? 62.066 52.168 -14.017 1.00 10.95 ? 977 TYR A OH 1 ATOM 7802 N N . VAL A 1 978 ? 53.955 51.755 -11.136 1.00 7.28 ? 978 VAL A N 1 ATOM 7803 C CA . VAL A 1 978 ? 52.596 51.225 -11.088 1.00 8.13 ? 978 VAL A CA 1 ATOM 7804 C C . VAL A 1 978 ? 52.156 51.176 -12.560 1.00 7.90 ? 978 VAL A C 1 ATOM 7805 O O . VAL A 1 978 ? 52.235 52.224 -13.235 1.00 8.70 ? 978 VAL A O 1 ATOM 7806 C CB . VAL A 1 978 ? 51.615 52.125 -10.281 1.00 7.54 ? 978 VAL A CB 1 ATOM 7807 C CG1 . VAL A 1 978 ? 50.161 51.612 -10.436 1.00 8.25 ? 978 VAL A CG1 1 ATOM 7808 C CG2 . VAL A 1 978 ? 52.027 52.140 -8.793 1.00 8.76 ? 978 VAL A CG2 1 ATOM 7809 N N . LEU A 1 979 ? 51.741 50.005 -13.034 1.00 8.31 ? 979 LEU A N 1 ATOM 7810 C CA . LEU A 1 979 ? 51.295 49.787 -14.411 1.00 9.57 ? 979 LEU A CA 1 ATOM 7811 C C . LEU A 1 979 ? 49.813 49.555 -14.437 1.00 9.33 ? 979 LEU A C 1 ATOM 7812 O O . LEU A 1 979 ? 49.297 48.680 -13.743 1.00 11.60 ? 979 LEU A O 1 ATOM 7813 C CB . LEU A 1 979 ? 51.970 48.553 -15.010 1.00 12.03 ? 979 LEU A CB 1 ATOM 7814 C CG A LEU A 1 979 ? 53.438 48.706 -15.373 0.50 12.52 ? 979 LEU A CG 1 ATOM 7815 C CG B LEU A 1 979 ? 52.999 48.470 -16.134 0.50 16.05 ? 979 LEU A CG 1 ATOM 7816 C CD1 A LEU A 1 979 ? 53.942 47.389 -15.978 0.50 14.86 ? 979 LEU A CD1 1 ATOM 7817 C CD1 B LEU A 1 979 ? 52.886 47.090 -16.770 0.50 15.95 ? 979 LEU A CD1 1 ATOM 7818 C CD2 A LEU A 1 979 ? 53.569 49.818 -16.382 0.50 13.89 ? 979 LEU A CD2 1 ATOM 7819 C CD2 B LEU A 1 979 ? 52.848 49.520 -17.184 0.50 15.72 ? 979 LEU A CD2 1 ATOM 7820 N N . HIS A 1 980 ? 49.118 50.329 -15.246 1.00 9.24 ? 980 HIS A N 1 ATOM 7821 C CA . HIS A 1 980 ? 47.672 50.172 -15.361 1.00 9.42 ? 980 HIS A CA 1 ATOM 7822 C C . HIS A 1 980 ? 47.280 49.873 -16.822 1.00 9.07 ? 980 HIS A C 1 ATOM 7823 O O . HIS A 1 980 ? 47.714 50.604 -17.693 1.00 10.37 ? 980 HIS A O 1 ATOM 7824 C CB . HIS A 1 980 ? 46.886 51.437 -14.929 1.00 9.84 ? 980 HIS A CB 1 ATOM 7825 C CG . HIS A 1 980 ? 45.414 51.217 -15.029 1.00 10.51 ? 980 HIS A CG 1 ATOM 7826 N ND1 . HIS A 1 980 ? 44.585 51.804 -15.967 1.00 11.69 ? 980 HIS A ND1 1 ATOM 7827 C CD2 . HIS A 1 980 ? 44.646 50.323 -14.365 1.00 7.46 ? 980 HIS A CD2 1 ATOM 7828 C CE1 . HIS A 1 980 ? 43.370 51.274 -15.877 1.00 8.40 ? 980 HIS A CE1 1 ATOM 7829 N NE2 . HIS A 1 980 ? 43.383 50.374 -14.912 1.00 13.41 ? 980 HIS A NE2 1 ATOM 7830 N N . ARG A 1 981 ? 46.483 48.832 -17.060 1.00 8.69 ? 981 ARG A N 1 ATOM 7831 C CA . ARG A 1 981 ? 46.020 48.591 -18.410 1.00 9.43 ? 981 ARG A CA 1 ATOM 7832 C C . ARG A 1 981 ? 44.531 48.779 -18.355 1.00 9.26 ? 981 ARG A C 1 ATOM 7833 O O . ARG A 1 981 ? 43.843 48.156 -17.564 1.00 9.22 ? 981 ARG A O 1 ATOM 7834 C CB . ARG A 1 981 ? 46.336 47.187 -18.851 1.00 12.19 ? 981 ARG A CB 1 ATOM 7835 C CG . ARG A 1 981 ? 46.087 47.033 -20.336 1.00 16.11 ? 981 ARG A CG 1 ATOM 7836 C CD . ARG A 1 981 ? 46.683 45.700 -20.767 1.00 20.43 ? 981 ARG A CD 1 ATOM 7837 N NE . ARG A 1 981 ? 46.167 45.396 -22.078 1.00 23.23 ? 981 ARG A NE 1 ATOM 7838 C CZ . ARG A 1 981 ? 46.243 44.188 -22.615 1.00 23.93 ? 981 ARG A CZ 1 ATOM 7839 N NH1 . ARG A 1 981 ? 46.826 43.215 -21.920 1.00 24.71 ? 981 ARG A NH1 1 ATOM 7840 N NH2 . ARG A 1 981 ? 45.719 43.947 -23.819 1.00 24.78 ? 981 ARG A NH2 1 ATOM 7841 N N . THR A 1 982 ? 44.030 49.675 -19.189 1.00 9.55 ? 982 THR A N 1 ATOM 7842 C CA . THR A 1 982 ? 42.566 49.870 -19.283 1.00 9.31 ? 982 THR A CA 1 ATOM 7843 C C . THR A 1 982 ? 42.023 48.828 -20.299 1.00 10.05 ? 982 THR A C 1 ATOM 7844 O O . THR A 1 982 ? 42.723 47.885 -20.645 1.00 11.32 ? 982 THR A O 1 ATOM 7845 C CB . THR A 1 982 ? 42.260 51.334 -19.737 1.00 8.85 ? 982 THR A CB 1 ATOM 7846 O OG1 . THR A 1 982 ? 40.862 51.603 -19.614 1.00 9.79 ? 982 THR A OG1 1 ATOM 7847 C CG2 . THR A 1 982 ? 42.697 51.610 -21.189 1.00 11.13 ? 982 THR A CG2 1 ATOM 7848 N N . ASN A 1 983 ? 40.745 48.908 -20.618 1.00 9.80 ? 983 ASN A N 1 ATOM 7849 C CA . ASN A 1 983 ? 40.182 48.012 -21.651 1.00 9.10 ? 983 ASN A CA 1 ATOM 7850 C C . ASN A 1 983 ? 39.452 48.884 -22.682 1.00 9.90 ? 983 ASN A C 1 ATOM 7851 O O . ASN A 1 983 ? 38.578 49.664 -22.319 1.00 11.19 ? 983 ASN A O 1 ATOM 7852 C CB . ASN A 1 983 ? 39.211 47.007 -21.055 1.00 9.16 ? 983 ASN A CB 1 ATOM 7853 C CG . ASN A 1 983 ? 38.708 46.054 -22.100 1.00 9.77 ? 983 ASN A CG 1 ATOM 7854 O OD1 . ASN A 1 983 ? 39.461 45.166 -22.483 1.00 11.94 ? 983 ASN A OD1 1 ATOM 7855 N ND2 . ASN A 1 983 ? 37.504 46.254 -22.585 1.00 10.80 ? 983 ASN A ND2 1 ATOM 7856 N N . LEU A 1 984 ? 39.920 48.811 -23.917 1.00 9.67 ? 984 LEU A N 1 ATOM 7857 C CA . LEU A 1 984 ? 39.345 49.588 -25.028 1.00 10.83 ? 984 LEU A CA 1 ATOM 7858 C C . LEU A 1 984 ? 38.528 48.687 -25.922 1.00 12.33 ? 984 LEU A C 1 ATOM 7859 O O . LEU A 1 984 ? 38.854 47.523 -26.095 1.00 12.84 ? 984 LEU A O 1 ATOM 7860 C CB . LEU A 1 984 ? 40.453 50.223 -25.862 1.00 11.98 ? 984 LEU A CB 1 ATOM 7861 C CG . LEU A 1 984 ? 41.421 51.054 -25.001 1.00 12.46 ? 984 LEU A CG 1 ATOM 7862 C CD1 . LEU A 1 984 ? 42.611 51.509 -25.905 1.00 14.34 ? 984 LEU A CD1 1 ATOM 7863 C CD2 . LEU A 1 984 ? 40.708 52.204 -24.372 1.00 12.21 ? 984 LEU A CD2 1 ATOM 7864 N N . MET A 1 985 ? 37.440 49.222 -26.449 1.00 12.37 ? 985 MET A N 1 ATOM 7865 C CA . MET A 1 985 ? 36.621 48.382 -27.326 1.00 14.70 ? 985 MET A CA 1 ATOM 7866 C C . MET A 1 985 ? 37.280 48.016 -28.623 1.00 15.28 ? 985 MET A C 1 ATOM 7867 O O . MET A 1 985 ? 38.062 48.798 -29.216 1.00 15.44 ? 985 MET A O 1 ATOM 7868 C CB . MET A 1 985 ? 35.318 49.078 -27.674 1.00 15.89 ? 985 MET A CB 1 ATOM 7869 C CG . MET A 1 985 ? 34.444 49.201 -26.477 1.00 17.89 ? 985 MET A CG 1 ATOM 7870 S SD . MET A 1 985 ? 32.730 49.386 -26.988 1.00 19.65 ? 985 MET A SD 1 ATOM 7871 C CE . MET A 1 985 ? 32.851 50.931 -27.816 1.00 20.67 ? 985 MET A CE 1 ATOM 7872 N N . GLN A 1 986 ? 36.995 46.786 -29.047 1.00 15.47 ? 986 GLN A N 1 ATOM 7873 C CA . GLN A 1 986 ? 37.471 46.263 -30.343 1.00 16.71 ? 986 GLN A CA 1 ATOM 7874 C C . GLN A 1 986 ? 36.446 46.772 -31.370 1.00 16.08 ? 986 GLN A C 1 ATOM 7875 O O . GLN A 1 986 ? 35.250 46.427 -31.287 1.00 16.06 ? 986 GLN A O 1 ATOM 7876 C CB . GLN A 1 986 ? 37.453 44.711 -30.341 1.00 18.75 ? 986 GLN A CB 1 ATOM 7877 C CG . GLN A 1 986 ? 38.476 44.075 -29.439 1.00 22.14 ? 986 GLN A CG 1 ATOM 7878 C CD . GLN A 1 986 ? 39.888 44.405 -29.865 1.00 24.95 ? 986 GLN A CD 1 ATOM 7879 O OE1 . GLN A 1 986 ? 40.766 44.617 -29.019 1.00 28.38 ? 986 GLN A OE1 1 ATOM 7880 N NE2 . GLN A 1 986 ? 40.128 44.450 -31.192 1.00 25.75 ? 986 GLN A NE2 1 ATOM 7881 N N . CYS A 1 987 ? 36.887 47.604 -32.313 1.00 16.80 ? 987 CYS A N 1 ATOM 7882 C CA . CYS A 1 987 ? 35.976 48.133 -33.324 1.00 18.18 ? 987 CYS A CA 1 ATOM 7883 C C . CYS A 1 987 ? 36.502 47.940 -34.736 1.00 19.81 ? 987 CYS A C 1 ATOM 7884 O O . CYS A 1 987 ? 36.013 48.607 -35.663 1.00 20.38 ? 987 CYS A O 1 ATOM 7885 C CB . CYS A 1 987 ? 35.676 49.613 -33.097 1.00 18.21 ? 987 CYS A CB 1 ATOM 7886 S SG . CYS A 1 987 ? 35.088 49.996 -31.412 1.00 19.33 ? 987 CYS A SG 1 ATOM 7887 N N . GLY A 1 988 ? 37.464 47.034 -34.892 1.00 21.29 ? 988 GLY A N 1 ATOM 7888 C CA . GLY A 1 988 ? 38.009 46.711 -36.204 1.00 27.42 ? 988 GLY A CA 1 ATOM 7889 C C . GLY A 1 988 ? 39.138 47.568 -36.677 1.00 31.91 ? 988 GLY A C 1 ATOM 7890 O O . GLY A 1 988 ? 39.477 47.553 -37.881 1.00 31.69 ? 988 GLY A O 1 ATOM 7891 N N . THR A 1 989 ? 39.734 48.313 -35.747 1.00 35.98 ? 989 THR A N 1 ATOM 7892 C CA . THR A 1 989 ? 40.862 49.173 -36.079 1.00 40.85 ? 989 THR A CA 1 ATOM 7893 C C . THR A 1 989 ? 42.095 48.424 -35.612 1.00 44.20 ? 989 THR A C 1 ATOM 7894 O O . THR A 1 989 ? 42.471 48.505 -34.448 1.00 44.56 ? 989 THR A O 1 ATOM 7895 C CB . THR A 1 989 ? 40.811 50.499 -35.339 1.00 40.78 ? 989 THR A CB 1 ATOM 7896 O OG1 . THR A 1 989 ? 39.595 51.182 -35.649 1.00 41.06 ? 989 THR A OG1 1 ATOM 7897 C CG2 . THR A 1 989 ? 41.992 51.360 -35.752 1.00 41.72 ? 989 THR A CG2 1 ATOM 7898 N N . PRO A 1 990 ? 42.741 47.681 -36.528 1.00 47.67 ? 990 PRO A N 1 ATOM 7899 C CA . PRO A 1 990 ? 43.940 46.914 -36.181 1.00 50.16 ? 990 PRO A CA 1 ATOM 7900 C C . PRO A 1 990 ? 44.819 47.615 -35.143 1.00 52.46 ? 990 PRO A C 1 ATOM 7901 O O . PRO A 1 990 ? 44.808 47.240 -33.967 1.00 53.08 ? 990 PRO A O 1 ATOM 7902 C CB . PRO A 1 990 ? 44.646 46.748 -37.525 1.00 50.06 ? 990 PRO A CB 1 ATOM 7903 C CG . PRO A 1 990 ? 43.499 46.652 -38.496 1.00 49.61 ? 990 PRO A CG 1 ATOM 7904 C CD . PRO A 1 990 ? 42.586 47.774 -37.995 1.00 48.64 ? 990 PRO A CD 1 ATOM 7905 N N . GLU A 1 991 ? 45.547 48.649 -35.558 1.00 54.52 ? 991 GLU A N 1 ATOM 7906 C CA . GLU A 1 991 ? 46.455 49.329 -34.632 1.00 56.87 ? 991 GLU A CA 1 ATOM 7907 C C . GLU A 1 991 ? 47.418 48.240 -34.152 1.00 57.52 ? 991 GLU A C 1 ATOM 7908 O O . GLU A 1 991 ? 47.114 47.491 -33.224 1.00 57.96 ? 991 GLU A O 1 ATOM 7909 C CB . GLU A 1 991 ? 45.680 49.912 -33.446 1.00 57.63 ? 991 GLU A CB 1 ATOM 7910 C CG . GLU A 1 991 ? 44.666 50.981 -33.839 1.00 58.97 ? 991 GLU A CG 1 ATOM 7911 C CD . GLU A 1 991 ? 43.985 51.630 -32.640 1.00 59.60 ? 991 GLU A CD 1 ATOM 7912 O OE1 . GLU A 1 991 ? 43.174 50.955 -31.959 1.00 59.63 ? 991 GLU A OE1 1 ATOM 7913 O OE2 . GLU A 1 991 ? 44.272 52.821 -32.381 1.00 60.00 ? 991 GLU A OE2 1 ATOM 7914 N N . GLU A 1 992 ? 48.575 48.129 -34.785 1.00 58.17 ? 992 GLU A N 1 ATOM 7915 C CA . GLU A 1 992 ? 49.478 47.071 -34.377 1.00 58.66 ? 992 GLU A CA 1 ATOM 7916 C C . GLU A 1 992 ? 50.861 47.509 -33.996 1.00 57.42 ? 992 GLU A C 1 ATOM 7917 O O . GLU A 1 992 ? 51.057 48.592 -33.435 1.00 57.58 ? 992 GLU A O 1 ATOM 7918 C CB . GLU A 1 992 ? 49.574 46.011 -35.478 1.00 60.84 ? 992 GLU A CB 1 ATOM 7919 C CG . GLU A 1 992 ? 48.247 45.314 -35.788 1.00 63.59 ? 992 GLU A CG 1 ATOM 7920 C CD . GLU A 1 992 ? 47.614 44.653 -34.559 1.00 65.24 ? 992 GLU A CD 1 ATOM 7921 O OE1 . GLU A 1 992 ? 48.171 44.762 -33.430 1.00 65.95 ? 992 GLU A OE1 1 ATOM 7922 O OE2 . GLU A 1 992 ? 46.546 44.019 -34.732 1.00 66.34 ? 992 GLU A OE2 1 ATOM 7923 N N . HIS A 1 993 ? 51.809 46.631 -34.320 1.00 55.66 ? 993 HIS A N 1 ATOM 7924 C CA . HIS A 1 993 ? 53.236 46.806 -34.058 1.00 53.49 ? 993 HIS A CA 1 ATOM 7925 C C . HIS A 1 993 ? 53.632 47.670 -32.869 1.00 50.11 ? 993 HIS A C 1 ATOM 7926 O O . HIS A 1 993 ? 54.019 48.843 -33.032 1.00 50.21 ? 993 HIS A O 1 ATOM 7927 C CB . HIS A 1 993 ? 53.995 47.301 -35.325 1.00 56.27 ? 993 HIS A CB 1 ATOM 7928 C CG . HIS A 1 993 ? 53.498 48.601 -35.892 1.00 58.63 ? 993 HIS A CG 1 ATOM 7929 N ND1 . HIS A 1 993 ? 52.327 48.702 -36.617 1.00 59.96 ? 993 HIS A ND1 1 ATOM 7930 C CD2 . HIS A 1 993 ? 54.029 49.848 -35.864 1.00 59.78 ? 993 HIS A CD2 1 ATOM 7931 C CE1 . HIS A 1 993 ? 52.159 49.953 -37.011 1.00 60.60 ? 993 HIS A CE1 1 ATOM 7932 N NE2 . HIS A 1 993 ? 53.178 50.670 -36.567 1.00 60.60 ? 993 HIS A NE2 1 ATOM 7933 N N . THR A 1 994 ? 53.508 47.106 -31.667 1.00 45.29 ? 994 THR A N 1 ATOM 7934 C CA . THR A 1 994 ? 53.954 47.835 -30.490 1.00 40.08 ? 994 THR A CA 1 ATOM 7935 C C . THR A 1 994 ? 54.951 46.971 -29.742 1.00 36.46 ? 994 THR A C 1 ATOM 7936 O O . THR A 1 994 ? 54.947 45.732 -29.834 1.00 36.24 ? 994 THR A O 1 ATOM 7937 C CB . THR A 1 994 ? 52.800 48.268 -29.546 1.00 40.08 ? 994 THR A CB 1 ATOM 7938 O OG1 . THR A 1 994 ? 52.066 47.125 -29.100 1.00 39.52 ? 994 THR A OG1 1 ATOM 7939 C CG2 . THR A 1 994 ? 51.876 49.227 -30.273 1.00 39.54 ? 994 THR A CG2 1 ATOM 7940 N N . GLN A 1 995 ? 55.807 47.634 -28.981 1.00 31.45 ? 995 GLN A N 1 ATOM 7941 C CA . GLN A 1 995 ? 56.839 46.937 -28.247 1.00 26.70 ? 995 GLN A CA 1 ATOM 7942 C C . GLN A 1 995 ? 56.437 46.577 -26.829 1.00 23.63 ? 995 GLN A C 1 ATOM 7943 O O . GLN A 1 995 ? 55.712 47.324 -26.176 1.00 21.45 ? 995 GLN A O 1 ATOM 7944 C CB . GLN A 1 995 ? 58.067 47.823 -28.175 1.00 26.52 ? 995 GLN A CB 1 ATOM 7945 C CG . GLN A 1 995 ? 58.546 48.285 -29.528 1.00 27.45 ? 995 GLN A CG 1 ATOM 7946 C CD . GLN A 1 995 ? 59.485 49.482 -29.429 1.00 28.60 ? 995 GLN A CD 1 ATOM 7947 O OE1 . GLN A 1 995 ? 59.078 50.580 -29.065 1.00 25.41 ? 995 GLN A OE1 1 ATOM 7948 N NE2 . GLN A 1 995 ? 60.763 49.264 -29.758 1.00 29.83 ? 995 GLN A NE2 1 ATOM 7949 N N . LYS A 1 996 ? 56.902 45.423 -26.365 1.00 20.95 ? 996 LYS A N 1 ATOM 7950 C CA . LYS A 1 996 ? 56.662 44.992 -25.001 1.00 20.71 ? 996 LYS A CA 1 ATOM 7951 C C . LYS A 1 996 ? 57.362 45.989 -24.062 1.00 18.89 ? 996 LYS A C 1 ATOM 7952 O O . LYS A 1 996 ? 58.541 46.376 -24.274 1.00 18.26 ? 996 LYS A O 1 ATOM 7953 C CB . LYS A 1 996 ? 57.268 43.566 -24.810 1.00 22.50 ? 996 LYS A CB 1 ATOM 7954 C CG . LYS A 1 996 ? 57.221 43.020 -23.382 1.00 26.04 ? 996 LYS A CG 1 ATOM 7955 C CD . LYS A 1 996 ? 57.813 41.570 -23.324 1.00 29.36 ? 996 LYS A CD 1 ATOM 7956 C CE . LYS A 1 996 ? 57.790 40.967 -21.901 1.00 31.11 ? 996 LYS A CE 1 ATOM 7957 N NZ . LYS A 1 996 ? 58.279 39.533 -21.927 1.00 33.86 ? 996 LYS A NZ 1 ATOM 7958 N N . LEU A 1 997 ? 56.642 46.387 -23.008 1.00 17.66 ? 997 LEU A N 1 ATOM 7959 C CA . LEU A 1 997 ? 57.252 47.268 -22.036 1.00 16.32 ? 997 LEU A CA 1 ATOM 7960 C C . LEU A 1 997 ? 57.607 46.451 -20.796 1.00 15.68 ? 997 LEU A C 1 ATOM 7961 O O . LEU A 1 997 ? 56.711 45.876 -20.165 1.00 16.82 ? 997 LEU A O 1 ATOM 7962 C CB . LEU A 1 997 ? 56.280 48.403 -21.665 1.00 16.58 ? 997 LEU A CB 1 ATOM 7963 C CG . LEU A 1 997 ? 56.827 49.261 -20.499 1.00 17.09 ? 997 LEU A CG 1 ATOM 7964 C CD1 . LEU A 1 997 ? 58.099 50.041 -20.829 1.00 18.24 ? 997 LEU A CD1 1 ATOM 7965 C CD2 . LEU A 1 997 ? 55.758 50.251 -20.151 1.00 17.66 ? 997 LEU A CD2 1 ATOM 7966 N N . ASP A 1 998 ? 58.912 46.376 -20.489 1.00 14.59 ? 998 ASP A N 1 ATOM 7967 C CA . ASP A 1 998 ? 59.376 45.689 -19.271 1.00 14.77 ? 998 ASP A CA 1 ATOM 7968 C C . ASP A 1 998 ? 59.957 46.790 -18.403 1.00 14.47 ? 998 ASP A C 1 ATOM 7969 O O . ASP A 1 998 ? 61.104 47.257 -18.620 1.00 14.09 ? 998 ASP A O 1 ATOM 7970 C CB . ASP A 1 998 ? 60.462 44.652 -19.609 1.00 15.50 ? 998 ASP A CB 1 ATOM 7971 C CG . ASP A 1 998 ? 61.141 44.129 -18.378 1.00 17.91 ? 998 ASP A CG 1 ATOM 7972 O OD1 . ASP A 1 998 ? 60.606 44.315 -17.249 1.00 17.44 ? 998 ASP A OD1 1 ATOM 7973 O OD2 . ASP A 1 998 ? 62.232 43.517 -18.545 1.00 19.31 ? 998 ASP A OD2 1 ATOM 7974 N N . VAL A 1 999 ? 59.171 47.262 -17.426 1.00 13.57 ? 999 VAL A N 1 ATOM 7975 C CA . VAL A 1 999 ? 59.703 48.378 -16.641 1.00 12.53 ? 999 VAL A CA 1 ATOM 7976 C C . VAL A 1 999 ? 60.954 48.075 -15.851 1.00 12.43 ? 999 VAL A C 1 ATOM 7977 O O . VAL A 1 999 ? 61.732 48.973 -15.500 1.00 12.75 ? 999 VAL A O 1 ATOM 7978 C CB . VAL A 1 999 ? 58.645 48.967 -15.673 1.00 12.28 ? 999 VAL A CB 1 ATOM 7979 C CG1 . VAL A 1 999 ? 57.486 49.597 -16.482 1.00 13.58 ? 999 VAL A CG1 1 ATOM 7980 C CG2 . VAL A 1 999 ? 58.080 47.903 -14.732 1.00 14.35 ? 999 VAL A CG2 1 ATOM 7981 N N . CYS A 1 1000 ? 61.166 46.786 -15.602 1.00 13.67 ? 1000 CYS A N 1 ATOM 7982 C CA . CYS A 1 1000 ? 62.334 46.454 -14.808 1.00 15.68 ? 1000 CYS A CA 1 ATOM 7983 C C . CYS A 1 1000 ? 63.670 46.660 -15.516 1.00 15.74 ? 1000 CYS A C 1 ATOM 7984 O O . CYS A 1 1000 ? 64.687 46.763 -14.859 1.00 16.62 ? 1000 CYS A O 1 ATOM 7985 C CB . CYS A 1 1000 ? 62.213 45.038 -14.228 1.00 17.33 ? 1000 CYS A CB 1 ATOM 7986 S SG . CYS A 1 1000 ? 61.313 45.070 -12.596 1.00 20.73 ? 1000 CYS A SG 1 ATOM 7987 N N . HIS A 1 1001 ? 63.632 46.814 -16.839 1.00 15.12 ? 1001 HIS A N 1 ATOM 7988 C CA . HIS A 1 1001 ? 64.858 47.045 -17.594 1.00 15.76 ? 1001 HIS A CA 1 ATOM 7989 C C . HIS A 1 1001 ? 64.926 48.494 -18.096 1.00 15.56 ? 1001 HIS A C 1 ATOM 7990 O O . HIS A 1 1001 ? 65.776 48.852 -18.914 1.00 17.57 ? 1001 HIS A O 1 ATOM 7991 C CB . HIS A 1 1001 ? 64.996 46.030 -18.756 1.00 16.71 ? 1001 HIS A CB 1 ATOM 7992 C CG . HIS A 1 1001 ? 65.547 44.707 -18.326 1.00 17.22 ? 1001 HIS A CG 1 ATOM 7993 N ND1 . HIS A 1 1001 ? 64.753 43.698 -17.837 1.00 18.36 ? 1001 HIS A ND1 1 ATOM 7994 C CD2 . HIS A 1 1001 ? 66.825 44.245 -18.258 1.00 18.42 ? 1001 HIS A CD2 1 ATOM 7995 C CE1 . HIS A 1 1001 ? 65.508 42.667 -17.484 1.00 18.27 ? 1001 HIS A CE1 1 ATOM 7996 N NE2 . HIS A 1 1001 ? 66.768 42.973 -17.732 1.00 18.09 ? 1001 HIS A NE2 1 ATOM 7997 N N . LEU A 1 1002 ? 64.037 49.372 -17.612 1.00 15.30 ? 1002 LEU A N 1 ATOM 7998 C CA . LEU A 1 1002 ? 64.114 50.777 -18.036 1.00 14.88 ? 1002 LEU A CA 1 ATOM 7999 C C . LEU A 1 1002 ? 65.380 51.458 -17.508 1.00 15.77 ? 1002 LEU A C 1 ATOM 8000 O O . LEU A 1 1002 ? 65.873 52.388 -18.155 1.00 17.71 ? 1002 LEU A O 1 ATOM 8001 C CB . LEU A 1 1002 ? 62.899 51.583 -17.544 1.00 13.95 ? 1002 LEU A CB 1 ATOM 8002 C CG . LEU A 1 1002 ? 61.682 51.391 -18.387 1.00 13.38 ? 1002 LEU A CG 1 ATOM 8003 C CD1 . LEU A 1 1002 ? 60.475 52.014 -17.651 1.00 13.10 ? 1002 LEU A CD1 1 ATOM 8004 C CD2 . LEU A 1 1002 ? 61.878 52.048 -19.730 1.00 15.59 ? 1002 LEU A CD2 1 ATOM 8005 N N . LEU A 1 1003 ? 65.883 51.046 -16.341 1.00 15.85 ? 1003 LEU A N 1 ATOM 8006 C CA . LEU A 1 1003 ? 67.118 51.592 -15.793 1.00 16.05 ? 1003 LEU A CA 1 ATOM 8007 C C . LEU A 1 1003 ? 68.146 50.477 -15.923 1.00 16.78 ? 1003 LEU A C 1 ATOM 8008 O O . LEU A 1 1003 ? 67.823 49.285 -15.777 1.00 17.39 ? 1003 LEU A O 1 ATOM 8009 C CB . LEU A 1 1003 ? 66.978 52.021 -14.333 1.00 16.52 ? 1003 LEU A CB 1 ATOM 8010 C CG . LEU A 1 1003 ? 66.298 53.395 -14.218 1.00 19.31 ? 1003 LEU A CG 1 ATOM 8011 C CD1 . LEU A 1 1003 ? 65.651 53.514 -12.877 1.00 21.39 ? 1003 LEU A CD1 1 ATOM 8012 C CD2 . LEU A 1 1003 ? 67.318 54.518 -14.486 1.00 21.01 ? 1003 LEU A CD2 1 ATOM 8013 N N . PRO A 1 1004 ? 69.399 50.859 -16.140 1.00 17.32 ? 1004 PRO A N 1 ATOM 8014 C CA . PRO A 1 1004 ? 70.423 49.827 -16.295 1.00 17.21 ? 1004 PRO A CA 1 ATOM 8015 C C . PRO A 1 1004 ? 70.841 49.120 -15.028 1.00 17.07 ? 1004 PRO A C 1 ATOM 8016 O O . PRO A 1 1004 ? 70.507 49.506 -13.891 1.00 16.47 ? 1004 PRO A O 1 ATOM 8017 C CB . PRO A 1 1004 ? 71.575 50.597 -16.908 1.00 18.05 ? 1004 PRO A CB 1 ATOM 8018 C CG . PRO A 1 1004 ? 71.487 51.923 -16.212 1.00 18.37 ? 1004 PRO A CG 1 ATOM 8019 C CD . PRO A 1 1004 ? 69.975 52.217 -16.222 1.00 17.51 ? 1004 PRO A CD 1 ATOM 8020 N N . ASN A 1 1005 ? 71.582 48.033 -15.254 1.00 17.48 ? 1005 ASN A N 1 ATOM 8021 C CA . ASN A 1 1005 ? 72.153 47.242 -14.171 1.00 17.22 ? 1005 ASN A CA 1 ATOM 8022 C C . ASN A 1 1005 ? 71.122 46.681 -13.215 1.00 16.60 ? 1005 ASN A C 1 ATOM 8023 O O . ASN A 1 1005 ? 71.316 46.709 -12.023 1.00 16.55 ? 1005 ASN A O 1 ATOM 8024 C CB . ASN A 1 1005 ? 73.145 48.087 -13.377 1.00 19.65 ? 1005 ASN A CB 1 ATOM 8025 C CG . ASN A 1 1005 ? 74.104 48.828 -14.271 1.00 22.94 ? 1005 ASN A CG 1 ATOM 8026 O OD1 . ASN A 1 1005 ? 74.177 50.061 -14.238 1.00 25.97 ? 1005 ASN A OD1 1 ATOM 8027 N ND2 . ASN A 1 1005 ? 74.820 48.096 -15.084 1.00 23.36 ? 1005 ASN A ND2 1 ATOM 8028 N N . VAL A 1 1006 ? 70.015 46.206 -13.751 1.00 17.20 ? 1006 VAL A N 1 ATOM 8029 C CA . VAL A 1 1006 ? 69.024 45.641 -12.879 1.00 17.19 ? 1006 VAL A CA 1 ATOM 8030 C C . VAL A 1 1006 ? 69.590 44.343 -12.275 1.00 17.25 ? 1006 VAL A C 1 ATOM 8031 O O . VAL A 1 1006 ? 70.293 43.565 -12.941 1.00 19.64 ? 1006 VAL A O 1 ATOM 8032 C CB . VAL A 1 1006 ? 67.656 45.396 -13.639 1.00 16.89 ? 1006 VAL A CB 1 ATOM 8033 C CG1 . VAL A 1 1006 ? 67.768 44.385 -14.733 1.00 18.09 ? 1006 VAL A CG1 1 ATOM 8034 C CG2 . VAL A 1 1006 ? 66.575 44.946 -12.619 1.00 17.35 ? 1006 VAL A CG2 1 ATOM 8035 N N . ALA A 1 1007 ? 69.299 44.154 -11.008 1.00 16.32 ? 1007 ALA A N 1 ATOM 8036 C CA . ALA A 1 1007 ? 69.747 42.979 -10.272 1.00 17.48 ? 1007 ALA A CA 1 ATOM 8037 C C . ALA A 1 1007 ? 68.584 42.165 -9.743 1.00 17.98 ? 1007 ALA A C 1 ATOM 8038 O O . ALA A 1 1007 ? 68.755 41.007 -9.371 1.00 18.94 ? 1007 ALA A O 1 ATOM 8039 C CB . ALA A 1 1007 ? 70.640 43.431 -9.121 1.00 17.46 ? 1007 ALA A CB 1 ATOM 8040 N N . ARG A 1 1008 ? 67.382 42.753 -9.684 1.00 17.51 ? 1008 ARG A N 1 ATOM 8041 C CA . ARG A 1 1008 ? 66.242 42.034 -9.158 1.00 16.90 ? 1008 ARG A CA 1 ATOM 8042 C C . ARG A 1 1008 ? 64.995 42.790 -9.593 1.00 15.64 ? 1008 ARG A C 1 ATOM 8043 O O . ARG A 1 1008 ? 65.046 44.013 -9.713 1.00 15.73 ? 1008 ARG A O 1 ATOM 8044 C CB . ARG A 1 1008 ? 66.305 42.017 -7.639 1.00 18.85 ? 1008 ARG A CB 1 ATOM 8045 C CG . ARG A 1 1008 ? 65.283 41.135 -6.998 1.00 22.17 ? 1008 ARG A CG 1 ATOM 8046 C CD . ARG A 1 1008 ? 65.385 41.324 -5.484 1.00 25.72 ? 1008 ARG A CD 1 ATOM 8047 N NE . ARG A 1 1008 ? 64.648 40.297 -4.757 1.00 30.16 ? 1008 ARG A NE 1 ATOM 8048 C CZ . ARG A 1 1008 ? 65.035 39.026 -4.665 1.00 32.25 ? 1008 ARG A CZ 1 ATOM 8049 N NH1 . ARG A 1 1008 ? 66.167 38.626 -5.257 1.00 33.68 ? 1008 ARG A NH1 1 ATOM 8050 N NH2 . ARG A 1 1008 ? 64.291 38.152 -3.982 1.00 32.90 ? 1008 ARG A NH2 1 ATOM 8051 N N . CYS A 1 1009 ? 63.911 42.071 -9.822 1.00 14.83 ? 1009 CYS A N 1 ATOM 8052 C CA . CYS A 1 1009 ? 62.631 42.686 -10.222 1.00 15.67 ? 1009 CYS A CA 1 ATOM 8053 C C . CYS A 1 1009 ? 61.577 41.937 -9.397 1.00 14.96 ? 1009 CYS A C 1 ATOM 8054 O O . CYS A 1 1009 ? 61.503 40.701 -9.463 1.00 15.36 ? 1009 CYS A O 1 ATOM 8055 C CB . CYS A 1 1009 ? 62.417 42.461 -11.696 1.00 16.99 ? 1009 CYS A CB 1 ATOM 8056 S SG . CYS A 1 1009 ? 60.833 43.150 -12.310 1.00 21.80 ? 1009 CYS A SG 1 ATOM 8057 N N . GLU A 1 1010 ? 60.742 42.679 -8.649 1.00 13.66 ? 1010 GLU A N 1 ATOM 8058 C CA . GLU A 1 1010 ? 59.723 42.094 -7.821 1.00 13.91 ? 1010 GLU A CA 1 ATOM 8059 C C . GLU A 1 1010 ? 58.355 42.678 -8.108 1.00 12.61 ? 1010 GLU A C 1 ATOM 8060 O O . GLU A 1 1010 ? 58.232 43.864 -8.399 1.00 12.94 ? 1010 GLU A O 1 ATOM 8061 C CB . GLU A 1 1010 ? 60.068 42.384 -6.349 1.00 15.68 ? 1010 GLU A CB 1 ATOM 8062 C CG . GLU A 1 1010 ? 61.321 41.574 -5.900 1.00 20.50 ? 1010 GLU A CG 1 ATOM 8063 C CD . GLU A 1 1010 ? 62.096 42.167 -4.723 1.00 23.20 ? 1010 GLU A CD 1 ATOM 8064 O OE1 . GLU A 1 1010 ? 62.555 43.342 -4.772 1.00 23.75 ? 1010 GLU A OE1 1 ATOM 8065 O OE2 . GLU A 1 1010 ? 62.260 41.424 -3.721 1.00 26.19 ? 1010 GLU A OE2 1 ATOM 8066 N N . ARG A 1 1011 ? 57.343 41.855 -8.046 1.00 12.69 ? 1011 ARG A N 1 ATOM 8067 C CA . ARG A 1 1011 ? 55.985 42.395 -8.080 1.00 11.43 ? 1011 ARG A CA 1 ATOM 8068 C C . ARG A 1 1011 ? 55.673 42.752 -6.619 1.00 11.11 ? 1011 ARG A C 1 ATOM 8069 O O . ARG A 1 1011 ? 56.001 42.004 -5.669 1.00 11.73 ? 1011 ARG A O 1 ATOM 8070 C CB . ARG A 1 1011 ? 55.008 41.358 -8.602 1.00 13.24 ? 1011 ARG A CB 1 ATOM 8071 C CG . ARG A 1 1011 ? 53.622 42.043 -8.839 1.00 16.42 ? 1011 ARG A CG 1 ATOM 8072 C CD . ARG A 1 1011 ? 52.659 41.156 -9.531 1.00 19.88 ? 1011 ARG A CD 1 ATOM 8073 N NE . ARG A 1 1011 ? 52.353 40.001 -8.715 1.00 23.49 ? 1011 ARG A NE 1 ATOM 8074 C CZ . ARG A 1 1011 ? 51.371 39.956 -7.807 1.00 26.13 ? 1011 ARG A CZ 1 ATOM 8075 N NH1 . ARG A 1 1011 ? 50.587 41.028 -7.605 1.00 27.71 ? 1011 ARG A NH1 1 ATOM 8076 N NH2 . ARG A 1 1011 ? 51.164 38.843 -7.095 1.00 27.64 ? 1011 ARG A NH2 1 ATOM 8077 N N . THR A 1 1012 ? 55.032 43.907 -6.408 1.00 10.07 ? 1012 THR A N 1 ATOM 8078 C CA . THR A 1 1012 ? 54.707 44.330 -5.050 1.00 9.19 ? 1012 THR A CA 1 ATOM 8079 C C . THR A 1 1012 ? 53.252 44.780 -4.946 1.00 9.28 ? 1012 THR A C 1 ATOM 8080 O O . THR A 1 1012 ? 52.543 44.930 -5.946 1.00 10.34 ? 1012 THR A O 1 ATOM 8081 C CB . THR A 1 1012 ? 55.572 45.557 -4.598 1.00 9.72 ? 1012 THR A CB 1 ATOM 8082 O OG1 . THR A 1 1012 ? 55.260 46.701 -5.439 1.00 11.00 ? 1012 THR A OG1 1 ATOM 8083 C CG2 . THR A 1 1012 ? 57.067 45.277 -4.831 1.00 11.41 ? 1012 THR A CG2 1 ATOM 8084 N N . THR A 1 1013 ? 52.820 44.986 -3.706 1.00 8.85 ? 1013 THR A N 1 ATOM 8085 C CA . THR A 1 1013 ? 51.527 45.646 -3.524 1.00 9.10 ? 1013 THR A CA 1 ATOM 8086 C C . THR A 1 1013 ? 51.637 47.067 -4.146 1.00 8.53 ? 1013 THR A C 1 ATOM 8087 O O . THR A 1 1013 ? 52.714 47.619 -4.381 1.00 8.38 ? 1013 THR A O 1 ATOM 8088 C CB . THR A 1 1013 ? 51.213 45.793 -2.060 1.00 8.74 ? 1013 THR A CB 1 ATOM 8089 O OG1 . THR A 1 1013 ? 52.393 46.225 -1.371 1.00 9.91 ? 1013 THR A OG1 1 ATOM 8090 C CG2 . THR A 1 1013 ? 50.703 44.433 -1.478 1.00 11.16 ? 1013 THR A CG2 1 ATOM 8091 N N . LEU A 1 1014 ? 50.479 47.687 -4.400 1.00 8.32 ? 1014 LEU A N 1 ATOM 8092 C CA . LEU A 1 1014 ? 50.510 48.992 -5.105 1.00 7.81 ? 1014 LEU A CA 1 ATOM 8093 C C . LEU A 1 1014 ? 51.166 50.134 -4.394 1.00 6.30 ? 1014 LEU A C 1 ATOM 8094 O O . LEU A 1 1014 ? 51.523 51.131 -5.020 1.00 8.12 ? 1014 LEU A O 1 ATOM 8095 C CB . LEU A 1 1014 ? 49.077 49.430 -5.532 1.00 8.18 ? 1014 LEU A CB 1 ATOM 8096 C CG . LEU A 1 1014 ? 48.299 48.464 -6.428 1.00 7.60 ? 1014 LEU A CG 1 ATOM 8097 C CD1 . LEU A 1 1014 ? 46.968 49.155 -6.830 1.00 8.21 ? 1014 LEU A CD1 1 ATOM 8098 C CD2 . LEU A 1 1014 ? 49.070 48.119 -7.731 1.00 9.21 ? 1014 LEU A CD2 1 ATOM 8099 N N . THR A 1 1015 ? 51.353 49.988 -3.076 1.00 7.28 ? 1015 THR A N 1 ATOM 8100 C CA . THR A 1 1015 ? 52.011 50.976 -2.215 1.00 7.65 ? 1015 THR A CA 1 ATOM 8101 C C . THR A 1 1015 ? 53.514 50.688 -2.149 1.00 7.36 ? 1015 THR A C 1 ATOM 8102 O O . THR A 1 1015 ? 54.216 51.437 -1.489 1.00 8.75 ? 1015 THR A O 1 ATOM 8103 C CB . THR A 1 1015 ? 51.497 50.835 -0.780 1.00 7.83 ? 1015 THR A CB 1 ATOM 8104 O OG1 . THR A 1 1015 ? 51.658 49.455 -0.425 1.00 8.43 ? 1015 THR A OG1 1 ATOM 8105 C CG2 . THR A 1 1015 ? 50.005 51.212 -0.689 1.00 9.48 ? 1015 THR A CG2 1 ATOM 8106 N N . PHE A 1 1016 ? 53.970 49.624 -2.824 1.00 7.90 ? 1016 PHE A N 1 ATOM 8107 C CA . PHE A 1 1016 ? 55.392 49.166 -2.856 1.00 8.93 ? 1016 PHE A CA 1 ATOM 8108 C C . PHE A 1 1016 ? 55.880 48.636 -1.512 1.00 10.44 ? 1016 PHE A C 1 ATOM 8109 O O . PHE A 1 1016 ? 57.062 48.324 -1.407 1.00 10.94 ? 1016 PHE A O 1 ATOM 8110 C CB . PHE A 1 1016 ? 56.348 50.307 -3.311 1.00 9.36 ? 1016 PHE A CB 1 ATOM 8111 C CG . PHE A 1 1016 ? 55.996 50.934 -4.640 1.00 9.05 ? 1016 PHE A CG 1 ATOM 8112 C CD1 . PHE A 1 1016 ? 55.895 50.170 -5.792 1.00 8.90 ? 1016 PHE A CD1 1 ATOM 8113 C CD2 . PHE A 1 1016 ? 55.800 52.321 -4.715 1.00 9.60 ? 1016 PHE A CD2 1 ATOM 8114 C CE1 . PHE A 1 1016 ? 55.582 50.802 -7.033 1.00 10.21 ? 1016 PHE A CE1 1 ATOM 8115 C CE2 . PHE A 1 1016 ? 55.504 52.941 -5.924 1.00 8.76 ? 1016 PHE A CE2 1 ATOM 8116 C CZ . PHE A 1 1016 ? 55.396 52.149 -7.088 1.00 9.66 ? 1016 PHE A CZ 1 ATOM 8117 N N . LEU A 1 1017 ? 54.969 48.420 -0.559 1.00 9.88 ? 1017 LEU A N 1 ATOM 8118 C CA . LEU A 1 1017 ? 55.394 48.009 0.796 1.00 10.75 ? 1017 LEU A CA 1 ATOM 8119 C C . LEU A 1 1017 ? 55.570 46.528 1.047 1.00 11.85 ? 1017 LEU A C 1 ATOM 8120 O O . LEU A 1 1017 ? 56.194 46.184 2.080 1.00 15.56 ? 1017 LEU A O 1 ATOM 8121 C CB . LEU A 1 1017 ? 54.438 48.631 1.827 1.00 11.15 ? 1017 LEU A CB 1 ATOM 8122 C CG . LEU A 1 1017 ? 54.428 50.150 1.768 1.00 10.39 ? 1017 LEU A CG 1 ATOM 8123 C CD1 . LEU A 1 1017 ? 53.377 50.655 2.766 1.00 10.16 ? 1017 LEU A CD1 1 ATOM 8124 C CD2 . LEU A 1 1017 ? 55.791 50.740 2.097 1.00 12.14 ? 1017 LEU A CD2 1 ATOM 8125 N N . GLN A 1 1018 ? 55.097 45.672 0.149 1.00 11.34 ? 1018 GLN A N 1 ATOM 8126 C CA . GLN A 1 1018 ? 55.271 44.240 0.350 1.00 12.66 ? 1018 GLN A CA 1 ATOM 8127 C C . GLN A 1 1018 ? 55.612 43.567 -0.965 1.00 12.77 ? 1018 GLN A C 1 ATOM 8128 O O . GLN A 1 1018 ? 54.972 43.822 -1.986 1.00 12.74 ? 1018 GLN A O 1 ATOM 8129 C CB . GLN A 1 1018 ? 53.997 43.605 0.924 1.00 13.81 ? 1018 GLN A CB 1 ATOM 8130 C CG . GLN A 1 1018 ? 54.175 42.063 1.138 1.00 17.73 ? 1018 GLN A CG 1 ATOM 8131 C CD . GLN A 1 1018 ? 52.877 41.317 1.425 1.00 21.49 ? 1018 GLN A CD 1 ATOM 8132 O OE1 . GLN A 1 1018 ? 51.803 41.898 1.496 1.00 22.50 ? 1018 GLN A OE1 1 ATOM 8133 N NE2 . GLN A 1 1018 ? 52.986 39.985 1.588 1.00 23.20 ? 1018 GLN A NE2 1 ATOM 8134 N N . ASN A 1 1019 ? 56.637 42.697 -0.935 1.00 13.56 ? 1019 ASN A N 1 ATOM 8135 C CA . ASN A 1 1019 ? 57.048 41.951 -2.100 1.00 15.09 ? 1019 ASN A CA 1 ATOM 8136 C C . ASN A 1 1019 ? 56.149 40.760 -2.243 1.00 16.44 ? 1019 ASN A C 1 ATOM 8137 O O . ASN A 1 1019 ? 55.978 39.965 -1.281 1.00 17.65 ? 1019 ASN A O 1 ATOM 8138 C CB . ASN A 1 1019 ? 58.536 41.518 -1.991 1.00 16.62 ? 1019 ASN A CB 1 ATOM 8139 C CG . ASN A 1 1019 ? 59.470 42.711 -1.901 1.00 18.82 ? 1019 ASN A CG 1 ATOM 8140 O OD1 . ASN A 1 1019 ? 59.211 43.742 -2.502 1.00 19.84 ? 1019 ASN A OD1 1 ATOM 8141 N ND2 . ASN A 1 1019 ? 60.577 42.582 -1.150 1.00 20.32 ? 1019 ASN A ND2 1 ATOM 8142 N N . LEU A 1 1020 ? 55.557 40.610 -3.407 1.00 16.02 ? 1020 LEU A N 1 ATOM 8143 C CA . LEU A 1 1020 ? 54.637 39.511 -3.654 1.00 17.77 ? 1020 LEU A CA 1 ATOM 8144 C C . LEU A 1 1020 ? 55.208 38.407 -4.528 1.00 18.77 ? 1020 LEU A C 1 ATOM 8145 O O . LEU A 1 1020 ? 54.761 37.243 -4.449 1.00 19.84 ? 1020 LEU A O 1 ATOM 8146 C CB . LEU A 1 1020 ? 53.357 40.007 -4.341 1.00 17.54 ? 1020 LEU A CB 1 ATOM 8147 C CG . LEU A 1 1020 ? 52.594 41.104 -3.612 1.00 17.41 ? 1020 LEU A CG 1 ATOM 8148 C CD1 . LEU A 1 1020 ? 51.453 41.585 -4.530 1.00 19.29 ? 1020 LEU A CD1 1 ATOM 8149 C CD2 . LEU A 1 1020 ? 52.048 40.576 -2.251 1.00 18.09 ? 1020 LEU A CD2 1 ATOM 8150 N N . GLU A 1 1021 ? 56.164 38.745 -5.377 1.00 18.96 ? 1021 GLU A N 1 ATOM 8151 C CA . GLU A 1 1021 ? 56.718 37.756 -6.319 1.00 21.01 ? 1021 GLU A CA 1 ATOM 8152 C C . GLU A 1 1021 ? 58.091 38.175 -6.795 1.00 21.05 ? 1021 GLU A C 1 ATOM 8153 O O . GLU A 1 1021 ? 58.321 39.337 -7.129 1.00 18.94 ? 1021 GLU A O 1 ATOM 8154 C CB . GLU A 1 1021 ? 55.765 37.666 -7.510 1.00 23.57 ? 1021 GLU A CB 1 ATOM 8155 C CG . GLU A 1 1021 ? 56.027 36.602 -8.532 1.00 29.06 ? 1021 GLU A CG 1 ATOM 8156 C CD . GLU A 1 1021 ? 54.984 36.626 -9.647 1.00 31.01 ? 1021 GLU A CD 1 ATOM 8157 O OE1 . GLU A 1 1021 ? 54.117 37.555 -9.671 1.00 33.24 ? 1021 GLU A OE1 1 ATOM 8158 O OE2 . GLU A 1 1021 ? 55.045 35.710 -10.507 1.00 34.29 ? 1021 GLU A OE2 1 ATOM 8159 N N . HIS A 1 1022 ? 59.036 37.228 -6.829 1.00 21.54 ? 1022 HIS A N 1 ATOM 8160 C CA . HIS A 1 1022 ? 60.385 37.491 -7.282 1.00 22.02 ? 1022 HIS A CA 1 ATOM 8161 C C . HIS A 1 1022 ? 60.333 37.081 -8.740 1.00 21.80 ? 1022 HIS A C 1 ATOM 8162 O O . HIS A 1 1022 ? 60.023 35.932 -9.065 1.00 22.34 ? 1022 HIS A O 1 ATOM 8163 C CB . HIS A 1 1022 ? 61.366 36.631 -6.492 1.00 24.19 ? 1022 HIS A CB 1 ATOM 8164 C CG . HIS A 1 1022 ? 62.778 36.832 -6.908 1.00 26.80 ? 1022 HIS A CG 1 ATOM 8165 N ND1 . HIS A 1 1022 ? 63.690 35.795 -6.956 1.00 29.26 ? 1022 HIS A ND1 1 ATOM 8166 C CD2 . HIS A 1 1022 ? 63.437 37.941 -7.327 1.00 27.88 ? 1022 HIS A CD2 1 ATOM 8167 C CE1 . HIS A 1 1022 ? 64.849 36.256 -7.395 1.00 29.20 ? 1022 HIS A CE1 1 ATOM 8168 N NE2 . HIS A 1 1022 ? 64.725 37.554 -7.623 1.00 29.67 ? 1022 HIS A NE2 1 ATOM 8169 N N . LEU A 1 1023 ? 60.653 37.997 -9.636 1.00 20.82 ? 1023 LEU A N 1 ATOM 8170 C CA . LEU A 1 1023 ? 60.441 37.711 -11.028 1.00 21.62 ? 1023 LEU A CA 1 ATOM 8171 C C . LEU A 1 1023 ? 61.605 37.154 -11.817 1.00 22.31 ? 1023 LEU A C 1 ATOM 8172 O O . LEU A 1 1023 ? 62.715 37.716 -11.821 1.00 21.55 ? 1023 LEU A O 1 ATOM 8173 C CB . LEU A 1 1023 ? 59.914 38.980 -11.703 1.00 21.46 ? 1023 LEU A CB 1 ATOM 8174 C CG . LEU A 1 1023 ? 58.616 39.499 -11.086 1.00 22.28 ? 1023 LEU A CG 1 ATOM 8175 C CD1 . LEU A 1 1023 ? 58.396 40.937 -11.476 1.00 23.22 ? 1023 LEU A CD1 1 ATOM 8176 C CD2 . LEU A 1 1023 ? 57.457 38.610 -11.555 1.00 23.30 ? 1023 LEU A CD2 1 ATOM 8177 N N . ASP A 1 1024 ? 61.297 36.067 -12.524 1.00 25.45 ? 1024 ASP A N 1 ATOM 8178 C CA . ASP A 1 1024 ? 62.265 35.377 -13.375 1.00 26.94 ? 1024 ASP A CA 1 ATOM 8179 C C . ASP A 1 1024 ? 62.786 36.250 -14.472 1.00 26.74 ? 1024 ASP A C 1 ATOM 8180 O O . ASP A 1 1024 ? 62.019 36.961 -15.165 1.00 26.59 ? 1024 ASP A O 1 ATOM 8181 C CB . ASP A 1 1024 ? 61.636 34.157 -14.030 1.00 30.14 ? 1024 ASP A CB 1 ATOM 8182 C CG . ASP A 1 1024 ? 61.461 33.014 -13.065 1.00 32.79 ? 1024 ASP A CG 1 ATOM 8183 O OD1 . ASP A 1 1024 ? 62.291 32.926 -12.106 1.00 35.31 ? 1024 ASP A OD1 1 ATOM 8184 O OD2 . ASP A 1 1024 ? 60.507 32.211 -13.288 1.00 35.04 ? 1024 ASP A OD2 1 ATOM 8185 N N . GLY A 1 1025 ? 64.094 36.181 -14.638 1.00 25.20 ? 1025 GLY A N 1 ATOM 8186 C CA . GLY A 1 1025 ? 64.732 36.954 -15.675 1.00 24.85 ? 1025 GLY A CA 1 ATOM 8187 C C . GLY A 1 1025 ? 64.707 38.434 -15.414 1.00 23.58 ? 1025 GLY A C 1 ATOM 8188 O O . GLY A 1 1025 ? 65.139 39.202 -16.257 1.00 24.20 ? 1025 GLY A O 1 ATOM 8189 N N . MET A 1 1026 ? 64.234 38.827 -14.231 1.00 22.62 ? 1026 MET A N 1 ATOM 8190 C CA . MET A 1 1026 ? 64.141 40.241 -13.866 1.00 22.34 ? 1026 MET A CA 1 ATOM 8191 C C . MET A 1 1026 ? 63.232 40.929 -14.865 1.00 21.59 ? 1026 MET A C 1 ATOM 8192 O O . MET A 1 1026 ? 63.452 42.104 -15.209 1.00 21.35 ? 1026 MET A O 1 ATOM 8193 C CB . MET A 1 1026 ? 65.520 40.920 -13.859 1.00 22.71 ? 1026 MET A CB 1 ATOM 8194 C CG . MET A 1 1026 ? 66.507 40.244 -12.892 1.00 24.90 ? 1026 MET A CG 1 ATOM 8195 S SD . MET A 1 1026 ? 68.140 40.968 -12.819 1.00 27.96 ? 1026 MET A SD 1 ATOM 8196 C CE . MET A 1 1026 ? 68.762 40.613 -14.527 1.00 27.30 ? 1026 MET A CE 1 ATOM 8197 N N . VAL A 1 1027 ? 62.222 40.217 -15.350 1.00 21.06 ? 1027 VAL A N 1 ATOM 8198 C CA . VAL A 1 1027 ? 61.315 40.800 -16.326 1.00 21.88 ? 1027 VAL A CA 1 ATOM 8199 C C . VAL A 1 1027 ? 59.926 41.038 -15.708 1.00 22.81 ? 1027 VAL A C 1 ATOM 8200 O O . VAL A 1 1027 ? 59.318 40.133 -15.116 1.00 22.92 ? 1027 VAL A O 1 ATOM 8201 C CB . VAL A 1 1027 ? 61.177 39.899 -17.585 1.00 21.58 ? 1027 VAL A CB 1 ATOM 8202 C CG1 . VAL A 1 1027 ? 60.077 40.428 -18.502 1.00 23.22 ? 1027 VAL A CG1 1 ATOM 8203 C CG2 . VAL A 1 1027 ? 62.499 39.895 -18.371 1.00 22.38 ? 1027 VAL A CG2 1 ATOM 8204 N N . ALA A 1 1028 ? 59.429 42.264 -15.830 1.00 22.49 ? 1028 ALA A N 1 ATOM 8205 C CA . ALA A 1 1028 ? 58.103 42.585 -15.283 1.00 23.21 ? 1028 ALA A CA 1 ATOM 8206 C C . ALA A 1 1028 ? 57.110 42.374 -16.388 1.00 23.44 ? 1028 ALA A C 1 ATOM 8207 O O . ALA A 1 1028 ? 57.123 43.122 -17.369 1.00 24.35 ? 1028 ALA A O 1 ATOM 8208 C CB . ALA A 1 1028 ? 58.042 44.050 -14.834 1.00 22.47 ? 1028 ALA A CB 1 ATOM 8209 N N . PRO A 1 1029 ? 56.243 41.361 -16.263 1.00 23.41 ? 1029 PRO A N 1 ATOM 8210 C CA . PRO A 1 1029 ? 55.253 41.134 -17.327 1.00 24.28 ? 1029 PRO A CA 1 ATOM 8211 C C . PRO A 1 1029 ? 54.186 42.240 -17.404 1.00 23.81 ? 1029 PRO A C 1 ATOM 8212 O O . PRO A 1 1029 ? 53.893 42.905 -16.422 1.00 25.31 ? 1029 PRO A O 1 ATOM 8213 C CB . PRO A 1 1029 ? 54.590 39.815 -16.947 1.00 24.22 ? 1029 PRO A CB 1 ATOM 8214 C CG . PRO A 1 1029 ? 55.194 39.401 -15.595 1.00 24.34 ? 1029 PRO A CG 1 ATOM 8215 C CD . PRO A 1 1029 ? 56.022 40.512 -15.077 1.00 23.23 ? 1029 PRO A CD 1 ATOM 8216 N N . GLU A 1 1030 ? 53.604 42.436 -18.571 1.00 23.93 ? 1030 GLU A N 1 ATOM 8217 C CA . GLU A 1 1030 ? 52.533 43.408 -18.672 1.00 23.79 ? 1030 GLU A CA 1 ATOM 8218 C C . GLU A 1 1030 ? 51.285 42.793 -18.033 1.00 23.37 ? 1030 GLU A C 1 ATOM 8219 O O . GLU A 1 1030 ? 51.149 41.554 -17.875 1.00 25.24 ? 1030 GLU A O 1 ATOM 8220 C CB . GLU A 1 1030 ? 52.263 43.770 -20.139 1.00 23.38 ? 1030 GLU A CB 1 ATOM 8221 C CG . GLU A 1 1030 ? 53.466 44.462 -20.835 1.00 23.46 ? 1030 GLU A CG 1 ATOM 8222 C CD . GLU A 1 1030 ? 53.122 44.901 -22.245 1.00 24.07 ? 1030 GLU A CD 1 ATOM 8223 O OE1 . GLU A 1 1030 ? 52.082 44.421 -22.757 1.00 25.84 ? 1030 GLU A OE1 1 ATOM 8224 O OE2 . GLU A 1 1030 ? 53.881 45.703 -22.856 1.00 22.24 ? 1030 GLU A OE2 1 ATOM 8225 N N . VAL A 1 1031 ? 50.378 43.676 -17.672 1.00 22.18 ? 1031 VAL A N 1 ATOM 8226 C CA . VAL A 1 1031 ? 49.170 43.291 -16.991 1.00 19.19 ? 1031 VAL A CA 1 ATOM 8227 C C . VAL A 1 1031 ? 47.977 43.111 -17.925 1.00 17.87 ? 1031 VAL A C 1 ATOM 8228 O O . VAL A 1 1031 ? 48.006 43.493 -19.087 1.00 17.37 ? 1031 VAL A O 1 ATOM 8229 C CB . VAL A 1 1031 ? 48.849 44.335 -15.854 1.00 21.13 ? 1031 VAL A CB 1 ATOM 8230 C CG1 . VAL A 1 1031 ? 50.125 44.541 -14.983 1.00 22.62 ? 1031 VAL A CG1 1 ATOM 8231 C CG2 . VAL A 1 1031 ? 48.383 45.637 -16.425 1.00 20.69 ? 1031 VAL A CG2 1 ATOM 8232 N N . CYS A 1 1032 ? 46.957 42.453 -17.399 1.00 15.16 ? 1032 CYS A N 1 ATOM 8233 C CA . CYS A 1 1032 ? 45.714 42.200 -18.114 1.00 14.03 ? 1032 CYS A CA 1 ATOM 8234 C C . CYS A 1 1032 ? 44.790 43.422 -18.173 1.00 12.25 ? 1032 CYS A C 1 ATOM 8235 O O . CYS A 1 1032 ? 44.943 44.370 -17.388 1.00 11.89 ? 1032 CYS A O 1 ATOM 8236 C CB . CYS A 1 1032 ? 44.950 41.124 -17.384 1.00 14.29 ? 1032 CYS A CB 1 ATOM 8237 S SG . CYS A 1 1032 ? 45.747 39.487 -17.547 1.00 20.77 ? 1032 CYS A SG 1 ATOM 8238 N N . PRO A 1 1033 ? 43.836 43.437 -19.124 1.00 12.02 ? 1033 PRO A N 1 ATOM 8239 C CA . PRO A 1 1033 ? 42.909 44.568 -19.193 1.00 10.69 ? 1033 PRO A CA 1 ATOM 8240 C C . PRO A 1 1033 ? 42.186 44.734 -17.859 1.00 9.81 ? 1033 PRO A C 1 ATOM 8241 O O . PRO A 1 1033 ? 41.684 43.769 -17.236 1.00 10.25 ? 1033 PRO A O 1 ATOM 8242 C CB . PRO A 1 1033 ? 41.904 44.152 -20.296 1.00 11.95 ? 1033 PRO A CB 1 ATOM 8243 C CG . PRO A 1 1033 ? 42.766 43.254 -21.190 1.00 13.76 ? 1033 PRO A CG 1 ATOM 8244 C CD . PRO A 1 1033 ? 43.568 42.444 -20.195 1.00 13.44 ? 1033 PRO A CD 1 ATOM 8245 N N . MET A 1 1034 ? 42.088 46.003 -17.456 1.00 9.38 ? 1034 MET A N 1 ATOM 8246 C CA . MET A 1 1034 ? 41.482 46.470 -16.200 1.00 10.08 ? 1034 MET A CA 1 ATOM 8247 C C . MET A 1 1034 ? 42.271 46.082 -14.966 1.00 11.24 ? 1034 MET A C 1 ATOM 8248 O O . MET A 1 1034 ? 41.800 46.326 -13.855 1.00 15.35 ? 1034 MET A O 1 ATOM 8249 C CB . MET A 1 1034 ? 40.013 46.043 -16.021 1.00 9.86 ? 1034 MET A CB 1 ATOM 8250 C CG . MET A 1 1034 ? 39.160 46.534 -17.149 1.00 11.27 ? 1034 MET A CG 1 ATOM 8251 S SD . MET A 1 1034 ? 39.182 48.351 -17.382 1.00 12.45 ? 1034 MET A SD 1 ATOM 8252 C CE . MET A 1 1034 ? 38.285 48.914 -15.820 1.00 13.45 ? 1034 MET A CE 1 ATOM 8253 N N . GLU A 1 1035 ? 43.501 45.638 -15.133 1.00 9.97 ? 1035 GLU A N 1 ATOM 8254 C CA . GLU A 1 1035 ? 44.325 45.278 -14.001 1.00 10.57 ? 1035 GLU A CA 1 ATOM 8255 C C . GLU A 1 1035 ? 45.382 46.341 -13.790 1.00 9.88 ? 1035 GLU A C 1 ATOM 8256 O O . GLU A 1 1035 ? 45.747 47.101 -14.690 1.00 9.88 ? 1035 GLU A O 1 ATOM 8257 C CB . GLU A 1 1035 ? 44.958 43.903 -14.211 1.00 14.36 ? 1035 GLU A CB 1 ATOM 8258 C CG . GLU A 1 1035 ? 43.934 42.801 -13.882 1.00 20.49 ? 1035 GLU A CG 1 ATOM 8259 C CD . GLU A 1 1035 ? 43.628 42.766 -12.375 1.00 24.79 ? 1035 GLU A CD 1 ATOM 8260 O OE1 . GLU A 1 1035 ? 44.436 42.120 -11.648 1.00 28.12 ? 1035 GLU A OE1 1 ATOM 8261 O OE2 . GLU A 1 1035 ? 42.645 43.407 -11.929 1.00 27.13 ? 1035 GLU A OE2 1 ATOM 8262 N N . THR A 1 1036 ? 45.836 46.423 -12.544 1.00 9.82 ? 1036 THR A N 1 ATOM 8263 C CA . THR A 1 1036 ? 46.870 47.364 -12.140 1.00 10.34 ? 1036 THR A CA 1 ATOM 8264 C C . THR A 1 1036 ? 47.849 46.532 -11.303 1.00 10.67 ? 1036 THR A C 1 ATOM 8265 O O . THR A 1 1036 ? 47.430 45.780 -10.426 1.00 12.02 ? 1036 THR A O 1 ATOM 8266 C CB . THR A 1 1036 ? 46.284 48.473 -11.260 1.00 10.70 ? 1036 THR A CB 1 ATOM 8267 O OG1 . THR A 1 1036 ? 45.203 49.116 -11.958 1.00 10.35 ? 1036 THR A OG1 1 ATOM 8268 C CG2 . THR A 1 1036 ? 47.373 49.528 -10.889 1.00 10.60 ? 1036 THR A CG2 1 ATOM 8269 N N . ALA A 1 1037 ? 49.142 46.675 -11.596 1.00 10.56 ? 1037 ALA A N 1 ATOM 8270 C CA . ALA A 1 1037 ? 50.187 45.960 -10.855 1.00 10.07 ? 1037 ALA A CA 1 ATOM 8271 C C . ALA A 1 1037 ? 51.321 46.898 -10.551 1.00 10.04 ? 1037 ALA A C 1 ATOM 8272 O O . ALA A 1 1037 ? 51.468 47.949 -11.194 1.00 11.20 ? 1037 ALA A O 1 ATOM 8273 C CB . ALA A 1 1037 ? 50.744 44.798 -11.706 1.00 13.17 ? 1037 ALA A CB 1 ATOM 8274 N N . ALA A 1 1038 ? 52.093 46.574 -9.528 1.00 8.37 ? 1038 ALA A N 1 ATOM 8275 C CA . ALA A 1 1038 ? 53.232 47.372 -9.183 1.00 9.30 ? 1038 ALA A CA 1 ATOM 8276 C C . ALA A 1 1038 ? 54.484 46.501 -9.207 1.00 9.30 ? 1038 ALA A C 1 ATOM 8277 O O . ALA A 1 1038 ? 54.453 45.323 -8.862 1.00 9.71 ? 1038 ALA A O 1 ATOM 8278 C CB . ALA A 1 1038 ? 53.050 48.006 -7.794 1.00 9.03 ? 1038 ALA A CB 1 ATOM 8279 N N . TYR A 1 1039 ? 55.564 47.105 -9.655 1.00 10.20 ? 1039 TYR A N 1 ATOM 8280 C CA . TYR A 1 1039 ? 56.859 46.421 -9.702 1.00 10.54 ? 1039 TYR A CA 1 ATOM 8281 C C . TYR A 1 1039 ? 57.940 47.287 -9.162 1.00 10.82 ? 1039 TYR A C 1 ATOM 8282 O O . TYR A 1 1039 ? 57.900 48.513 -9.313 1.00 11.93 ? 1039 TYR A O 1 ATOM 8283 C CB . TYR A 1 1039 ? 57.218 46.081 -11.146 1.00 11.99 ? 1039 TYR A CB 1 ATOM 8284 C CG . TYR A 1 1039 ? 56.245 45.193 -11.840 1.00 11.77 ? 1039 TYR A CG 1 ATOM 8285 C CD1 . TYR A 1 1039 ? 56.220 43.824 -11.600 1.00 14.06 ? 1039 TYR A CD1 1 ATOM 8286 C CD2 . TYR A 1 1039 ? 55.307 45.732 -12.716 1.00 13.64 ? 1039 TYR A CD2 1 ATOM 8287 C CE1 . TYR A 1 1039 ? 55.277 42.998 -12.220 1.00 15.42 ? 1039 TYR A CE1 1 ATOM 8288 C CE2 . TYR A 1 1039 ? 54.376 44.928 -13.353 1.00 15.38 ? 1039 TYR A CE2 1 ATOM 8289 C CZ . TYR A 1 1039 ? 54.363 43.574 -13.110 1.00 16.85 ? 1039 TYR A CZ 1 ATOM 8290 O OH . TYR A 1 1039 ? 53.483 42.776 -13.834 1.00 20.06 ? 1039 TYR A OH 1 ATOM 8291 N N . VAL A 1 1040 ? 58.934 46.679 -8.507 1.00 11.62 ? 1040 VAL A N 1 ATOM 8292 C CA . VAL A 1 1040 ? 60.094 47.423 -8.031 1.00 11.84 ? 1040 VAL A CA 1 ATOM 8293 C C . VAL A 1 1040 ? 61.328 46.758 -8.663 1.00 11.44 ? 1040 VAL A C 1 ATOM 8294 O O . VAL A 1 1040 ? 61.524 45.532 -8.532 1.00 12.49 ? 1040 VAL A O 1 ATOM 8295 C CB . VAL A 1 1040 ? 60.226 47.372 -6.489 1.00 11.21 ? 1040 VAL A CB 1 ATOM 8296 C CG1 . VAL A 1 1040 ? 61.559 48.077 -6.063 1.00 12.96 ? 1040 VAL A CG1 1 ATOM 8297 C CG2 . VAL A 1 1040 ? 59.045 48.133 -5.842 1.00 12.46 ? 1040 VAL A CG2 1 ATOM 8298 N N . SER A 1 1041 ? 62.137 47.551 -9.361 1.00 10.45 ? 1041 SER A N 1 ATOM 8299 C CA . SER A 1 1041 ? 63.406 47.072 -9.898 1.00 11.84 ? 1041 SER A CA 1 ATOM 8300 C C . SER A 1 1041 ? 64.513 47.537 -8.949 1.00 12.41 ? 1041 SER A C 1 ATOM 8301 O O . SER A 1 1041 ? 64.504 48.662 -8.398 1.00 12.38 ? 1041 SER A O 1 ATOM 8302 C CB . SER A 1 1041 ? 63.619 47.576 -11.321 1.00 13.01 ? 1041 SER A CB 1 ATOM 8303 O OG . SER A 1 1041 ? 63.672 48.980 -11.395 1.00 14.07 ? 1041 SER A OG 1 ATOM 8304 N N . SER A 1 1042 ? 65.485 46.625 -8.730 1.00 13.56 ? 1042 SER A N 1 ATOM 8305 C CA . SER A 1 1042 ? 66.649 46.910 -7.867 1.00 13.66 ? 1042 SER A CA 1 ATOM 8306 C C . SER A 1 1042 ? 67.895 46.967 -8.763 1.00 14.36 ? 1042 SER A C 1 ATOM 8307 O O . SER A 1 1042 ? 68.013 46.173 -9.690 1.00 15.52 ? 1042 SER A O 1 ATOM 8308 C CB . SER A 1 1042 ? 66.824 45.804 -6.817 1.00 13.94 ? 1042 SER A CB 1 ATOM 8309 O OG . SER A 1 1042 ? 65.722 45.818 -5.915 1.00 14.87 ? 1042 SER A OG 1 ATOM 8310 N N . HIS A 1 1043 ? 68.757 47.937 -8.498 1.00 14.70 ? 1043 HIS A N 1 ATOM 8311 C CA . HIS A 1 1043 ? 69.932 48.197 -9.353 1.00 15.50 ? 1043 HIS A CA 1 ATOM 8312 C C . HIS A 1 1043 ? 71.192 48.314 -8.537 1.00 17.05 ? 1043 HIS A C 1 ATOM 8313 O O . HIS A 1 1043 ? 71.235 48.992 -7.498 1.00 16.96 ? 1043 HIS A O 1 ATOM 8314 C CB . HIS A 1 1043 ? 69.678 49.480 -10.153 1.00 14.12 ? 1043 HIS A CB 1 ATOM 8315 C CG . HIS A 1 1043 ? 68.371 49.448 -10.893 1.00 13.41 ? 1043 HIS A CG 1 ATOM 8316 N ND1 . HIS A 1 1043 ? 68.259 48.995 -12.192 1.00 14.04 ? 1043 HIS A ND1 1 ATOM 8317 C CD2 . HIS A 1 1043 ? 67.103 49.704 -10.470 1.00 12.34 ? 1043 HIS A CD2 1 ATOM 8318 C CE1 . HIS A 1 1043 ? 66.981 48.979 -12.548 1.00 13.67 ? 1043 HIS A CE1 1 ATOM 8319 N NE2 . HIS A 1 1043 ? 66.265 49.405 -11.507 1.00 12.92 ? 1043 HIS A NE2 1 ATOM 8320 N N . SER A 1 1044 ? 72.212 47.619 -9.056 1.00 20.20 ? 1044 SER A N 1 ATOM 8321 C CA . SER A 1 1044 ? 73.495 47.556 -8.395 1.00 23.34 ? 1044 SER A CA 1 ATOM 8322 C C . SER A 1 1044 ? 74.449 48.678 -8.754 1.00 24.22 ? 1044 SER A C 1 ATOM 8323 O O . SER A 1 1044 ? 74.185 49.481 -9.693 1.00 25.22 ? 1044 SER A O 1 ATOM 8324 C CB . SER A 1 1044 ? 74.143 46.186 -8.675 1.00 24.03 ? 1044 SER A CB 1 ATOM 8325 O OG . SER A 1 1044 ? 74.169 45.900 -10.072 1.00 26.50 ? 1044 SER A OG 1 HETATM 8326 C C1 . NAG B 2 . ? 58.346 44.912 12.701 1.00 35.36 ? 1802 NAG A C1 1 HETATM 8327 C C2 . NAG B 2 . ? 59.459 44.559 13.666 1.00 38.86 ? 1802 NAG A C2 1 HETATM 8328 C C3 . NAG B 2 . ? 59.950 43.162 13.393 1.00 40.36 ? 1802 NAG A C3 1 HETATM 8329 C C4 . NAG B 2 . ? 58.809 42.182 13.524 1.00 41.30 ? 1802 NAG A C4 1 HETATM 8330 C C5 . NAG B 2 . ? 57.748 42.576 12.487 1.00 41.44 ? 1802 NAG A C5 1 HETATM 8331 C C6 . NAG B 2 . ? 56.519 41.678 12.523 1.00 42.71 ? 1802 NAG A C6 1 HETATM 8332 C C7 . NAG B 2 . ? 60.831 46.361 14.497 1.00 43.50 ? 1802 NAG A C7 1 HETATM 8333 C C8 . NAG B 2 . ? 61.571 45.831 15.712 1.00 45.03 ? 1802 NAG A C8 1 HETATM 8334 N N2 . NAG B 2 . ? 60.556 45.499 13.521 1.00 41.41 ? 1802 NAG A N2 1 HETATM 8335 O O3 . NAG B 2 . ? 60.942 42.861 14.342 1.00 41.02 ? 1802 NAG A O3 1 HETATM 8336 O O4 . NAG B 2 . ? 59.291 40.861 13.297 1.00 42.92 ? 1802 NAG A O4 1 HETATM 8337 O O5 . NAG B 2 . ? 57.292 43.933 12.733 1.00 38.41 ? 1802 NAG A O5 1 HETATM 8338 O O6 . NAG B 2 . ? 56.675 40.549 11.661 1.00 45.67 ? 1802 NAG A O6 1 HETATM 8339 O O7 . NAG B 2 . ? 60.523 47.555 14.447 1.00 45.24 ? 1802 NAG A O7 1 HETATM 8340 P P . PO4 C 3 . ? 45.237 65.478 -29.819 1.00 21.28 ? 1803 PO4 A P 1 HETATM 8341 O O1 . PO4 C 3 . ? 44.767 66.823 -30.483 1.00 26.96 ? 1803 PO4 A O1 1 HETATM 8342 O O2 . PO4 C 3 . ? 46.608 65.016 -30.310 1.00 26.10 ? 1803 PO4 A O2 1 HETATM 8343 O O3 . PO4 C 3 . ? 44.112 64.407 -30.114 1.00 27.54 ? 1803 PO4 A O3 1 HETATM 8344 O O4 . PO4 C 3 . ? 45.329 65.762 -28.304 1.00 27.61 ? 1803 PO4 A O4 1 HETATM 8345 ZN ZN . ZN D 4 . ? 34.459 64.087 7.921 1.00 7.92 ? 1805 ZN A ZN 1 HETATM 8346 C C15 . GB1 E 5 . ? 27.365 67.513 11.671 1.00 15.24 ? 1804 GB1 A C15 1 HETATM 8347 C C14 . GB1 E 5 . ? 27.127 68.895 11.774 1.00 18.26 ? 1804 GB1 A C14 1 HETATM 8348 C C13 . GB1 E 5 . ? 28.038 69.716 12.418 1.00 15.64 ? 1804 GB1 A C13 1 HETATM 8349 C C12 . GB1 E 5 . ? 29.150 69.095 12.941 1.00 16.82 ? 1804 GB1 A C12 1 HETATM 8350 C C11 . GB1 E 5 . ? 29.431 67.727 12.865 1.00 14.67 ? 1804 GB1 A C11 1 HETATM 8351 C C10 . GB1 E 5 . ? 28.509 66.901 12.209 1.00 15.40 ? 1804 GB1 A C10 1 HETATM 8352 C C8 . GB1 E 5 . ? 28.761 65.382 12.122 1.00 13.17 ? 1804 GB1 A C8 1 HETATM 8353 C C9 . GB1 E 5 . ? 28.903 64.845 13.539 1.00 14.59 ? 1804 GB1 A C9 1 HETATM 8354 O O9 . GB1 E 5 . ? 29.026 63.444 13.365 1.00 13.98 ? 1804 GB1 A O9 1 HETATM 8355 N N7 . GB1 E 5 . ? 29.900 65.263 11.183 1.00 12.29 ? 1804 GB1 A N7 1 HETATM 8356 C C6 . GB1 E 5 . ? 29.871 65.714 9.793 1.00 11.58 ? 1804 GB1 A C6 1 HETATM 8357 C C5 . GB1 E 5 . ? 31.019 65.192 8.945 1.00 9.52 ? 1804 GB1 A C5 1 HETATM 8358 N N1 . GB1 E 5 . ? 30.750 65.381 7.506 1.00 10.29 ? 1804 GB1 A N1 1 HETATM 8359 C C2 . GB1 E 5 . ? 31.244 66.641 6.960 1.00 8.93 ? 1804 GB1 A C2 1 HETATM 8360 C C3 . GB1 E 5 . ? 32.602 66.592 7.659 1.00 10.12 ? 1804 GB1 A C3 1 HETATM 8361 O O3 . GB1 E 5 . ? 33.616 65.869 6.994 1.00 9.26 ? 1804 GB1 A O3 1 HETATM 8362 C C4 . GB1 E 5 . ? 32.239 66.104 9.056 1.00 9.69 ? 1804 GB1 A C4 1 HETATM 8363 O O4 . GB1 E 5 . ? 33.221 65.174 9.470 1.00 10.30 ? 1804 GB1 A O4 1 HETATM 8364 C C1 . MPD F 6 . ? 14.744 60.981 10.271 1.00 14.23 ? 1801 MPD A C1 1 HETATM 8365 C C2 . MPD F 6 . ? 16.174 61.008 10.575 1.00 15.83 ? 1801 MPD A C2 1 HETATM 8366 O O2 . MPD F 6 . ? 16.810 59.991 9.703 1.00 20.72 ? 1801 MPD A O2 1 HETATM 8367 C CM . MPD F 6 . ? 16.764 62.369 10.201 1.00 18.60 ? 1801 MPD A CM 1 HETATM 8368 C C3 . MPD F 6 . ? 16.294 60.678 12.097 1.00 17.16 ? 1801 MPD A C3 1 HETATM 8369 C C4 . MPD F 6 . ? 17.697 60.501 12.715 1.00 16.15 ? 1801 MPD A C4 1 HETATM 8370 O O4 . MPD F 6 . ? 17.596 59.570 13.817 1.00 13.78 ? 1801 MPD A O4 1 HETATM 8371 C C5 . MPD F 6 . ? 18.253 61.862 13.243 1.00 16.77 ? 1801 MPD A C5 1 HETATM 8372 O O . HOH G 7 . ? 27.930 46.834 -31.294 1.00 29.75 ? 1806 HOH A O 1 HETATM 8373 O O . HOH G 7 . ? 28.558 43.875 -29.638 1.00 31.79 ? 1807 HOH A O 1 HETATM 8374 O O . HOH G 7 . ? 26.274 44.240 -27.244 1.00 32.13 ? 1808 HOH A O 1 HETATM 8375 O O . HOH G 7 . ? 27.009 41.456 -27.610 1.00 37.32 ? 1809 HOH A O 1 HETATM 8376 O O . HOH G 7 . ? 29.356 40.899 -25.560 1.00 22.29 ? 1810 HOH A O 1 HETATM 8377 O O . HOH G 7 . ? 28.602 41.105 -21.686 1.00 13.00 ? 1811 HOH A O 1 HETATM 8378 O O . HOH G 7 . ? 27.810 38.498 -22.663 1.00 31.71 ? 1812 HOH A O 1 HETATM 8379 O O . HOH G 7 . ? 27.639 36.244 -19.545 1.00 24.13 ? 1813 HOH A O 1 HETATM 8380 O O . HOH G 7 . ? 29.439 34.917 -16.399 1.00 27.89 ? 1814 HOH A O 1 HETATM 8381 O O . HOH G 7 . ? 25.630 36.146 -15.498 1.00 30.97 ? 1815 HOH A O 1 HETATM 8382 O O . HOH G 7 . ? 23.670 37.526 -17.573 1.00 31.42 ? 1816 HOH A O 1 HETATM 8383 O O . HOH G 7 . ? 23.094 39.109 -15.358 1.00 25.78 ? 1817 HOH A O 1 HETATM 8384 O O . HOH G 7 . ? 24.106 41.780 -14.601 1.00 20.60 ? 1818 HOH A O 1 HETATM 8385 O O . HOH G 7 . ? 21.993 42.473 -13.175 1.00 21.30 ? 1819 HOH A O 1 HETATM 8386 O O . HOH G 7 . ? 22.214 40.560 -11.258 1.00 17.80 ? 1820 HOH A O 1 HETATM 8387 O O . HOH G 7 . ? 20.167 39.071 -12.158 1.00 40.39 ? 1821 HOH A O 1 HETATM 8388 O O . HOH G 7 . ? 19.523 41.837 -14.295 1.00 41.75 ? 1822 HOH A O 1 HETATM 8389 O O . HOH G 7 . ? 17.315 45.501 -14.037 1.00 30.23 ? 1823 HOH A O 1 HETATM 8390 O O . HOH G 7 . ? 19.889 46.611 -14.225 1.00 15.54 ? 1824 HOH A O 1 HETATM 8391 O O . HOH G 7 . ? 22.482 45.194 -13.422 1.00 15.45 ? 1825 HOH A O 1 HETATM 8392 O O . HOH G 7 . ? 23.585 45.766 -15.812 1.00 17.88 ? 1826 HOH A O 1 HETATM 8393 O O . HOH G 7 . ? 21.367 46.520 -17.420 1.00 27.77 ? 1827 HOH A O 1 HETATM 8394 O O . HOH G 7 . ? 18.073 48.534 -19.777 1.00 35.44 ? 1828 HOH A O 1 HETATM 8395 O O . HOH G 7 . ? 16.855 50.725 -19.232 1.00 20.90 ? 1829 HOH A O 1 HETATM 8396 O O . HOH G 7 . ? 16.331 52.814 -22.463 1.00 29.84 ? 1830 HOH A O 1 HETATM 8397 O O . HOH G 7 . ? 16.271 52.830 -25.558 1.00 37.59 ? 1831 HOH A O 1 HETATM 8398 O O . HOH G 7 . ? 19.580 52.410 -27.018 1.00 28.64 ? 1832 HOH A O 1 HETATM 8399 O O . HOH G 7 . ? 20.019 52.573 -24.230 1.00 15.56 ? 1833 HOH A O 1 HETATM 8400 O O . HOH G 7 . ? 19.081 50.143 -23.330 1.00 30.54 ? 1834 HOH A O 1 HETATM 8401 O O . HOH G 7 . ? 22.791 52.914 -24.391 1.00 12.22 ? 1835 HOH A O 1 HETATM 8402 O O . HOH G 7 . ? 24.655 50.930 -24.079 1.00 12.90 ? 1836 HOH A O 1 HETATM 8403 O O . HOH G 7 . ? 23.989 48.272 -24.194 1.00 32.31 ? 1837 HOH A O 1 HETATM 8404 O O . HOH G 7 . ? 22.730 48.094 -26.843 1.00 40.19 ? 1838 HOH A O 1 HETATM 8405 O O . HOH G 7 . ? 22.452 50.320 -27.295 1.00 37.28 ? 1839 HOH A O 1 HETATM 8406 O O . HOH G 7 . ? 19.363 51.850 -31.097 1.00 34.34 ? 1840 HOH A O 1 HETATM 8407 O O . HOH G 7 . ? 22.387 56.657 -34.223 1.00 16.11 ? 1841 HOH A O 1 HETATM 8408 O O . HOH G 7 . ? 21.516 55.384 -36.461 1.00 28.74 ? 1842 HOH A O 1 HETATM 8409 O O . HOH G 7 . ? 19.448 58.357 -36.764 1.00 23.63 ? 1843 HOH A O 1 HETATM 8410 O O . HOH G 7 . ? 18.702 60.518 -37.931 1.00 23.45 ? 1844 HOH A O 1 HETATM 8411 O O . HOH G 7 . ? 20.662 60.871 -40.329 1.00 30.22 ? 1845 HOH A O 1 HETATM 8412 O O . HOH G 7 . ? 25.029 58.761 -38.586 1.00 42.04 ? 1846 HOH A O 1 HETATM 8413 O O . HOH G 7 . ? 24.887 59.258 -36.253 1.00 38.47 ? 1847 HOH A O 1 HETATM 8414 O O . HOH G 7 . ? 21.698 61.354 -34.834 1.00 27.61 ? 1848 HOH A O 1 HETATM 8415 O O . HOH G 7 . ? 22.416 63.219 -33.021 1.00 20.10 ? 1849 HOH A O 1 HETATM 8416 O O . HOH G 7 . ? 20.711 58.806 -34.500 1.00 16.70 ? 1850 HOH A O 1 HETATM 8417 O O . HOH G 7 . ? 16.722 57.156 -36.125 1.00 38.06 ? 1851 HOH A O 1 HETATM 8418 O O . HOH G 7 . ? 20.807 51.077 -38.435 1.00 27.17 ? 1852 HOH A O 1 HETATM 8419 O O . HOH G 7 . ? 21.696 48.682 -38.996 1.00 40.49 ? 1853 HOH A O 1 HETATM 8420 O O . HOH G 7 . ? 22.877 48.709 -36.382 1.00 33.65 ? 1854 HOH A O 1 HETATM 8421 O O . HOH G 7 . ? 31.796 51.032 -35.482 1.00 22.25 ? 1855 HOH A O 1 HETATM 8422 O O . HOH G 7 . ? 34.777 53.457 -33.197 1.00 34.87 ? 1856 HOH A O 1 HETATM 8423 O O . HOH G 7 . ? 35.436 55.288 -34.749 1.00 36.53 ? 1857 HOH A O 1 HETATM 8424 O O . HOH G 7 . ? 36.545 56.448 -32.756 1.00 28.18 ? 1858 HOH A O 1 HETATM 8425 O O . HOH G 7 . ? 36.927 58.795 -33.573 1.00 25.95 ? 1859 HOH A O 1 HETATM 8426 O O . HOH G 7 . ? 34.746 59.326 -34.933 1.00 22.15 ? 1860 HOH A O 1 HETATM 8427 O O . HOH G 7 . ? 33.515 56.900 -35.976 1.00 17.49 ? 1861 HOH A O 1 HETATM 8428 O O . HOH G 7 . ? 30.819 58.127 -40.338 1.00 42.92 ? 1862 HOH A O 1 HETATM 8429 O O . HOH G 7 . ? 28.064 59.664 -38.847 1.00 30.02 ? 1863 HOH A O 1 HETATM 8430 O O . HOH G 7 . ? 28.981 62.048 -39.825 1.00 23.15 ? 1864 HOH A O 1 HETATM 8431 O O . HOH G 7 . ? 34.434 65.770 -42.383 1.00 34.74 ? 1865 HOH A O 1 HETATM 8432 O O . HOH G 7 . ? 34.257 70.064 -44.884 1.00 39.79 ? 1866 HOH A O 1 HETATM 8433 O O . HOH G 7 . ? 30.990 69.101 -45.555 1.00 37.50 ? 1867 HOH A O 1 HETATM 8434 O O . HOH G 7 . ? 28.007 68.051 -47.018 1.00 38.49 ? 1868 HOH A O 1 HETATM 8435 O O . HOH G 7 . ? 28.795 69.591 -39.609 1.00 23.30 ? 1869 HOH A O 1 HETATM 8436 O O . HOH G 7 . ? 24.657 71.440 -39.914 1.00 27.30 ? 1870 HOH A O 1 HETATM 8437 O O . HOH G 7 . ? 26.019 76.095 -39.103 1.00 26.67 ? 1871 HOH A O 1 HETATM 8438 O O . HOH G 7 . ? 27.311 75.977 -41.430 1.00 36.04 ? 1872 HOH A O 1 HETATM 8439 O O . HOH G 7 . ? 31.193 78.804 -42.842 1.00 32.63 ? 1873 HOH A O 1 HETATM 8440 O O . HOH G 7 . ? 29.530 81.106 -43.212 1.00 42.94 ? 1874 HOH A O 1 HETATM 8441 O O . HOH G 7 . ? 26.059 81.358 -42.841 1.00 35.18 ? 1875 HOH A O 1 HETATM 8442 O O . HOH G 7 . ? 23.342 82.502 -40.605 1.00 23.78 ? 1876 HOH A O 1 HETATM 8443 O O . HOH G 7 . ? 22.083 80.608 -42.259 1.00 36.04 ? 1877 HOH A O 1 HETATM 8444 O O . HOH G 7 . ? 21.995 79.949 -35.955 1.00 25.69 ? 1878 HOH A O 1 HETATM 8445 O O . HOH G 7 . ? 20.663 79.813 -33.484 1.00 39.24 ? 1879 HOH A O 1 HETATM 8446 O O . HOH G 7 . ? 22.929 78.388 -30.352 1.00 23.54 ? 1880 HOH A O 1 HETATM 8447 O O . HOH G 7 . ? 22.887 77.274 -27.326 1.00 24.11 ? 1881 HOH A O 1 HETATM 8448 O O . HOH G 7 . ? 20.626 77.817 -27.528 1.00 34.23 ? 1882 HOH A O 1 HETATM 8449 O O . HOH G 7 . ? 19.305 78.900 -25.569 1.00 36.20 ? 1883 HOH A O 1 HETATM 8450 O O . HOH G 7 . ? 21.000 79.316 -23.479 1.00 21.09 ? 1884 HOH A O 1 HETATM 8451 O O . HOH G 7 . ? 23.158 78.262 -24.792 1.00 16.53 ? 1885 HOH A O 1 HETATM 8452 O O . HOH G 7 . ? 19.093 83.238 -25.761 1.00 28.30 ? 1886 HOH A O 1 HETATM 8453 O O . HOH G 7 . ? 21.496 85.957 -30.988 1.00 28.93 ? 1887 HOH A O 1 HETATM 8454 O O . HOH G 7 . ? 23.213 86.846 -32.540 1.00 31.71 ? 1888 HOH A O 1 HETATM 8455 O O . HOH G 7 . ? 25.572 86.044 -31.910 1.00 17.02 ? 1889 HOH A O 1 HETATM 8456 O O . HOH G 7 . ? 27.158 89.740 -31.691 1.00 37.18 ? 1890 HOH A O 1 HETATM 8457 O O . HOH G 7 . ? 25.733 91.581 -32.890 1.00 35.66 ? 1891 HOH A O 1 HETATM 8458 O O . HOH G 7 . ? 26.683 91.589 -27.683 1.00 28.33 ? 1892 HOH A O 1 HETATM 8459 O O . HOH G 7 . ? 28.063 90.801 -25.363 1.00 20.06 ? 1893 HOH A O 1 HETATM 8460 O O . HOH G 7 . ? 29.509 88.593 -26.238 1.00 13.45 ? 1894 HOH A O 1 HETATM 8461 O O . HOH G 7 . ? 27.046 87.793 -23.608 1.00 22.35 ? 1895 HOH A O 1 HETATM 8462 O O . HOH G 7 . ? 25.157 88.519 -25.411 1.00 31.07 ? 1896 HOH A O 1 HETATM 8463 O O . HOH G 7 . ? 23.703 90.762 -26.118 1.00 33.44 ? 1897 HOH A O 1 HETATM 8464 O O . HOH G 7 . ? 22.770 88.702 -18.805 1.00 38.04 ? 1898 HOH A O 1 HETATM 8465 O O . HOH G 7 . ? 21.596 86.011 -19.256 1.00 27.33 ? 1899 HOH A O 1 HETATM 8466 O O . HOH G 7 . ? 19.739 84.183 -18.440 1.00 29.84 ? 1900 HOH A O 1 HETATM 8467 O O . HOH G 7 . ? 17.459 81.306 -17.215 1.00 41.52 ? 1901 HOH A O 1 HETATM 8468 O O . HOH G 7 . ? 18.840 80.340 -11.713 1.00 34.78 ? 1902 HOH A O 1 HETATM 8469 O O . HOH G 7 . ? 18.290 82.511 -11.467 1.00 38.54 ? 1903 HOH A O 1 HETATM 8470 O O . HOH G 7 . ? 18.231 81.822 -8.948 1.00 35.92 ? 1904 HOH A O 1 HETATM 8471 O O . HOH G 7 . ? 17.277 80.508 -7.318 1.00 21.86 ? 1905 HOH A O 1 HETATM 8472 O O . HOH G 7 . ? 16.575 81.934 -5.120 1.00 32.56 ? 1906 HOH A O 1 HETATM 8473 O O . HOH G 7 . ? 18.123 84.465 -5.019 1.00 35.82 ? 1907 HOH A O 1 HETATM 8474 O O . HOH G 7 . ? 18.202 84.426 -7.993 1.00 40.97 ? 1908 HOH A O 1 HETATM 8475 O O . HOH G 7 . ? 20.893 83.723 -12.267 1.00 26.81 ? 1909 HOH A O 1 HETATM 8476 O O . HOH G 7 . ? 24.866 83.036 -16.967 1.00 19.99 ? 1910 HOH A O 1 HETATM 8477 O O . HOH G 7 . ? 27.682 86.240 -14.626 1.00 26.38 ? 1911 HOH A O 1 HETATM 8478 O O . HOH G 7 . ? 30.231 87.007 -15.130 1.00 22.28 ? 1912 HOH A O 1 HETATM 8479 O O . HOH G 7 . ? 29.649 87.163 -17.963 1.00 23.52 ? 1913 HOH A O 1 HETATM 8480 O O . HOH G 7 . ? 31.643 85.733 -19.868 1.00 21.73 ? 1914 HOH A O 1 HETATM 8481 O O . HOH G 7 . ? 33.308 84.218 -18.320 1.00 15.70 ? 1915 HOH A O 1 HETATM 8482 O O . HOH G 7 . ? 35.352 86.014 -17.992 1.00 26.06 ? 1916 HOH A O 1 HETATM 8483 O O . HOH G 7 . ? 40.051 85.858 -22.020 1.00 25.14 ? 1917 HOH A O 1 HETATM 8484 O O . HOH G 7 . ? 40.768 83.071 -23.409 1.00 38.98 ? 1918 HOH A O 1 HETATM 8485 O O . HOH G 7 . ? 39.563 81.402 -22.103 1.00 34.34 ? 1919 HOH A O 1 HETATM 8486 O O . HOH G 7 . ? 41.781 79.154 -23.586 1.00 27.19 ? 1920 HOH A O 1 HETATM 8487 O O . HOH G 7 . ? 43.454 80.824 -25.318 1.00 37.52 ? 1921 HOH A O 1 HETATM 8488 O O . HOH G 7 . ? 45.838 81.982 -25.529 1.00 43.01 ? 1922 HOH A O 1 HETATM 8489 O O . HOH G 7 . ? 44.288 83.515 -28.071 1.00 26.71 ? 1923 HOH A O 1 HETATM 8490 O O . HOH G 7 . ? 44.724 82.395 -30.611 1.00 21.61 ? 1924 HOH A O 1 HETATM 8491 O O . HOH G 7 . ? 41.371 82.548 -28.972 1.00 33.16 ? 1925 HOH A O 1 HETATM 8492 O O . HOH G 7 . ? 40.543 82.753 -31.337 1.00 26.36 ? 1926 HOH A O 1 HETATM 8493 O O . HOH G 7 . ? 38.133 81.587 -31.394 1.00 11.28 ? 1927 HOH A O 1 HETATM 8494 O O . HOH G 7 . ? 39.103 83.102 -27.494 1.00 22.04 ? 1928 HOH A O 1 HETATM 8495 O O . HOH G 7 . ? 41.400 83.405 -26.175 1.00 33.81 ? 1929 HOH A O 1 HETATM 8496 O O . HOH G 7 . ? 43.257 79.029 -27.600 1.00 41.33 ? 1930 HOH A O 1 HETATM 8497 O O . HOH G 7 . ? 42.816 78.327 -29.711 1.00 31.43 ? 1931 HOH A O 1 HETATM 8498 O O . HOH G 7 . ? 42.413 79.593 -31.745 1.00 28.35 ? 1932 HOH A O 1 HETATM 8499 O O . HOH G 7 . ? 44.615 79.074 -33.391 1.00 19.53 ? 1933 HOH A O 1 HETATM 8500 O O . HOH G 7 . ? 44.534 76.110 -28.362 1.00 27.47 ? 1934 HOH A O 1 HETATM 8501 O O . HOH G 7 . ? 46.321 76.849 -26.136 1.00 25.46 ? 1935 HOH A O 1 HETATM 8502 O O . HOH G 7 . ? 44.885 71.839 -26.005 1.00 39.14 ? 1936 HOH A O 1 HETATM 8503 O O . HOH G 7 . ? 47.310 70.555 -24.997 1.00 38.05 ? 1937 HOH A O 1 HETATM 8504 O O . HOH G 7 . ? 47.129 67.506 -24.728 1.00 20.79 ? 1938 HOH A O 1 HETATM 8505 O O . HOH G 7 . ? 45.891 67.947 -26.997 1.00 14.87 ? 1939 HOH A O 1 HETATM 8506 O O . HOH G 7 . ? 47.292 69.829 -28.661 1.00 21.61 ? 1940 HOH A O 1 HETATM 8507 O O . HOH G 7 . ? 47.364 68.045 -30.900 1.00 17.96 ? 1941 HOH A O 1 HETATM 8508 O O . HOH G 7 . ? 43.386 66.643 -32.350 1.00 27.71 ? 1942 HOH A O 1 HETATM 8509 O O . HOH G 7 . ? 41.258 68.133 -32.569 1.00 17.56 ? 1943 HOH A O 1 HETATM 8510 O O . HOH G 7 . ? 39.282 68.914 -35.390 1.00 15.73 ? 1944 HOH A O 1 HETATM 8511 O O . HOH G 7 . ? 38.556 68.989 -38.195 1.00 16.76 ? 1945 HOH A O 1 HETATM 8512 O O . HOH G 7 . ? 39.688 75.377 -40.323 1.00 18.14 ? 1946 HOH A O 1 HETATM 8513 O O . HOH G 7 . ? 42.118 74.634 -41.468 1.00 27.76 ? 1947 HOH A O 1 HETATM 8514 O O . HOH G 7 . ? 43.680 72.356 -42.009 1.00 19.69 ? 1948 HOH A O 1 HETATM 8515 O O . HOH G 7 . ? 44.650 71.861 -44.653 1.00 43.72 ? 1949 HOH A O 1 HETATM 8516 O O . HOH G 7 . ? 46.324 70.066 -39.897 1.00 36.11 ? 1950 HOH A O 1 HETATM 8517 O O . HOH G 7 . ? 46.546 70.042 -36.697 1.00 18.38 ? 1951 HOH A O 1 HETATM 8518 O O . HOH G 7 . ? 48.924 68.947 -36.946 1.00 30.65 ? 1952 HOH A O 1 HETATM 8519 O O . HOH G 7 . ? 51.515 69.911 -38.180 1.00 27.74 ? 1953 HOH A O 1 HETATM 8520 O O . HOH G 7 . ? 53.943 71.026 -36.990 1.00 13.41 ? 1954 HOH A O 1 HETATM 8521 O O . HOH G 7 . ? 55.397 68.764 -37.812 1.00 28.62 ? 1955 HOH A O 1 HETATM 8522 O O . HOH G 7 . ? 56.745 69.711 -39.791 1.00 29.31 ? 1956 HOH A O 1 HETATM 8523 O O . HOH G 7 . ? 59.907 68.472 -39.009 1.00 26.08 ? 1957 HOH A O 1 HETATM 8524 O O . HOH G 7 . ? 61.087 67.210 -36.852 1.00 28.17 ? 1958 HOH A O 1 HETATM 8525 O O . HOH G 7 . ? 59.403 67.019 -34.881 1.00 25.89 ? 1959 HOH A O 1 HETATM 8526 O O . HOH G 7 . ? 56.811 67.511 -35.593 1.00 22.55 ? 1960 HOH A O 1 HETATM 8527 O O . HOH G 7 . ? 56.060 64.982 -36.211 1.00 26.17 ? 1961 HOH A O 1 HETATM 8528 O O . HOH G 7 . ? 58.639 64.530 -36.889 1.00 34.02 ? 1962 HOH A O 1 HETATM 8529 O O . HOH G 7 . ? 61.766 63.666 -30.802 1.00 22.56 ? 1963 HOH A O 1 HETATM 8530 O O . HOH G 7 . ? 64.021 65.582 -30.180 1.00 34.94 ? 1964 HOH A O 1 HETATM 8531 O O . HOH G 7 . ? 63.371 67.739 -31.760 1.00 23.09 ? 1965 HOH A O 1 HETATM 8532 O O . HOH G 7 . ? 69.702 63.727 -28.800 1.00 26.59 ? 1966 HOH A O 1 HETATM 8533 O O . HOH G 7 . ? 72.046 63.334 -27.341 1.00 46.61 ? 1967 HOH A O 1 HETATM 8534 O O . HOH G 7 . ? 69.893 62.850 -23.792 1.00 33.84 ? 1968 HOH A O 1 HETATM 8535 O O . HOH G 7 . ? 70.159 61.649 -20.400 1.00 23.59 ? 1969 HOH A O 1 HETATM 8536 O O . HOH G 7 . ? 71.720 62.448 -18.139 1.00 28.60 ? 1970 HOH A O 1 HETATM 8537 O O . HOH G 7 . ? 72.735 63.934 -21.050 1.00 31.93 ? 1971 HOH A O 1 HETATM 8538 O O . HOH G 7 . ? 73.906 65.867 -17.579 1.00 15.79 ? 1972 HOH A O 1 HETATM 8539 O O . HOH G 7 . ? 75.185 64.159 -16.112 1.00 29.28 ? 1973 HOH A O 1 HETATM 8540 O O . HOH G 7 . ? 77.636 66.012 -11.924 1.00 32.24 ? 1974 HOH A O 1 HETATM 8541 O O . HOH G 7 . ? 78.670 68.927 -11.940 1.00 21.95 ? 1975 HOH A O 1 HETATM 8542 O O . HOH G 7 . ? 81.315 68.342 -11.440 1.00 17.60 ? 1976 HOH A O 1 HETATM 8543 O O . HOH G 7 . ? 81.656 66.861 -13.658 1.00 17.42 ? 1977 HOH A O 1 HETATM 8544 O O . HOH G 7 . ? 83.656 66.207 -15.352 1.00 19.24 ? 1978 HOH A O 1 HETATM 8545 O O . HOH G 7 . ? 84.337 68.140 -17.282 1.00 14.65 ? 1979 HOH A O 1 HETATM 8546 O O . HOH G 7 . ? 83.679 69.917 -20.113 1.00 22.94 ? 1980 HOH A O 1 HETATM 8547 O O . HOH G 7 . ? 83.592 67.339 -22.825 1.00 21.36 ? 1981 HOH A O 1 HETATM 8548 O O . HOH G 7 . ? 80.427 64.018 -21.343 1.00 22.43 ? 1982 HOH A O 1 HETATM 8549 O O . HOH G 7 . ? 79.205 62.737 -23.528 1.00 40.68 ? 1983 HOH A O 1 HETATM 8550 O O . HOH G 7 . ? 79.710 67.931 -15.213 1.00 31.83 ? 1984 HOH A O 1 HETATM 8551 O O . HOH G 7 . ? 79.822 73.856 -17.518 1.00 26.02 ? 1985 HOH A O 1 HETATM 8552 O O . HOH G 7 . ? 77.639 75.018 -17.620 1.00 34.07 ? 1986 HOH A O 1 HETATM 8553 O O . HOH G 7 . ? 75.536 73.848 -16.102 1.00 26.05 ? 1987 HOH A O 1 HETATM 8554 O O . HOH G 7 . ? 74.769 76.196 -14.459 1.00 25.69 ? 1988 HOH A O 1 HETATM 8555 O O . HOH G 7 . ? 73.734 78.252 -13.314 1.00 42.08 ? 1989 HOH A O 1 HETATM 8556 O O . HOH G 7 . ? 73.620 80.044 -10.906 1.00 37.98 ? 1990 HOH A O 1 HETATM 8557 O O . HOH G 7 . ? 74.607 77.923 -16.540 1.00 42.01 ? 1991 HOH A O 1 HETATM 8558 O O . HOH G 7 . ? 73.216 76.716 -18.520 1.00 27.25 ? 1992 HOH A O 1 HETATM 8559 O O . HOH G 7 . ? 74.641 77.326 -20.684 1.00 33.15 ? 1993 HOH A O 1 HETATM 8560 O O . HOH G 7 . ? 75.432 74.063 -19.522 1.00 23.25 ? 1994 HOH A O 1 HETATM 8561 O O . HOH G 7 . ? 76.722 73.989 -26.760 1.00 33.17 ? 1995 HOH A O 1 HETATM 8562 O O . HOH G 7 . ? 72.477 75.708 -27.204 1.00 35.94 ? 1996 HOH A O 1 HETATM 8563 O O . HOH G 7 . ? 71.755 73.733 -29.269 1.00 25.59 ? 1997 HOH A O 1 HETATM 8564 O O . HOH G 7 . ? 70.502 77.870 -26.262 1.00 21.96 ? 1998 HOH A O 1 HETATM 8565 O O . HOH G 7 . ? 71.065 79.718 -27.959 1.00 36.92 ? 1999 HOH A O 1 HETATM 8566 O O . HOH G 7 . ? 71.404 82.295 -27.664 1.00 30.77 ? 2000 HOH A O 1 HETATM 8567 O O . HOH G 7 . ? 70.071 82.852 -29.893 1.00 20.12 ? 2001 HOH A O 1 HETATM 8568 O O . HOH G 7 . ? 68.442 79.259 -28.667 1.00 20.48 ? 2002 HOH A O 1 HETATM 8569 O O . HOH G 7 . ? 67.729 78.761 -25.365 1.00 12.53 ? 2003 HOH A O 1 HETATM 8570 O O . HOH G 7 . ? 67.783 81.557 -25.722 1.00 12.98 ? 2004 HOH A O 1 HETATM 8571 O O . HOH G 7 . ? 66.827 84.284 -22.253 1.00 24.78 ? 2005 HOH A O 1 HETATM 8572 O O . HOH G 7 . ? 64.812 85.170 -22.695 1.00 32.08 ? 2006 HOH A O 1 HETATM 8573 O O . HOH G 7 . ? 62.269 85.166 -23.172 1.00 31.61 ? 2007 HOH A O 1 HETATM 8574 O O . HOH G 7 . ? 62.582 83.073 -21.474 1.00 39.24 ? 2008 HOH A O 1 HETATM 8575 O O . HOH G 7 . ? 62.114 80.577 -18.988 1.00 21.36 ? 2009 HOH A O 1 HETATM 8576 O O . HOH G 7 . ? 62.629 82.492 -17.220 1.00 38.45 ? 2010 HOH A O 1 HETATM 8577 O O . HOH G 7 . ? 63.618 82.125 -14.534 1.00 40.31 ? 2011 HOH A O 1 HETATM 8578 O O . HOH G 7 . ? 66.319 81.732 -14.314 1.00 25.36 ? 2012 HOH A O 1 HETATM 8579 O O . HOH G 7 . ? 66.666 81.226 -11.235 1.00 23.12 ? 2013 HOH A O 1 HETATM 8580 O O . HOH G 7 . ? 64.893 79.603 -9.066 1.00 34.87 ? 2014 HOH A O 1 HETATM 8581 O O . HOH G 7 . ? 65.348 78.731 -5.744 1.00 24.05 ? 2015 HOH A O 1 HETATM 8582 O O . HOH G 7 . ? 65.515 81.238 -4.866 1.00 29.18 ? 2016 HOH A O 1 HETATM 8583 O O . HOH G 7 . ? 64.799 78.940 -1.560 1.00 27.72 ? 2017 HOH A O 1 HETATM 8584 O O . HOH G 7 . ? 64.328 77.311 0.230 1.00 32.66 ? 2018 HOH A O 1 HETATM 8585 O O . HOH G 7 . ? 65.516 77.722 2.948 1.00 31.27 ? 2019 HOH A O 1 HETATM 8586 O O . HOH G 7 . ? 65.186 76.908 -3.669 1.00 35.38 ? 2020 HOH A O 1 HETATM 8587 O O . HOH G 7 . ? 66.742 74.352 -4.449 1.00 24.49 ? 2021 HOH A O 1 HETATM 8588 O O . HOH G 7 . ? 66.402 71.358 -6.817 1.00 16.06 ? 2022 HOH A O 1 HETATM 8589 O O . HOH G 7 . ? 64.064 70.613 -5.323 1.00 15.02 ? 2023 HOH A O 1 HETATM 8590 O O . HOH G 7 . ? 67.931 65.472 -3.366 1.00 14.89 ? 2024 HOH A O 1 HETATM 8591 O O . HOH G 7 . ? 65.966 66.020 -0.559 1.00 20.97 ? 2025 HOH A O 1 HETATM 8592 O O . HOH G 7 . ? 66.261 68.631 2.059 1.00 35.00 ? 2026 HOH A O 1 HETATM 8593 O O . HOH G 7 . ? 69.198 63.607 2.020 1.00 34.05 ? 2027 HOH A O 1 HETATM 8594 O O . HOH G 7 . ? 70.212 61.849 0.024 1.00 34.78 ? 2028 HOH A O 1 HETATM 8595 O O . HOH G 7 . ? 69.140 61.306 -2.362 1.00 14.11 ? 2029 HOH A O 1 HETATM 8596 O O . HOH G 7 . ? 67.453 60.574 -5.642 1.00 10.86 ? 2030 HOH A O 1 HETATM 8597 O O . HOH G 7 . ? 65.630 60.176 -7.676 1.00 10.69 ? 2031 HOH A O 1 HETATM 8598 O O . HOH G 7 . ? 63.087 61.200 -7.604 1.00 8.94 ? 2032 HOH A O 1 HETATM 8599 O O . HOH G 7 . ? 60.984 59.554 -8.266 1.00 8.17 ? 2033 HOH A O 1 HETATM 8600 O O . HOH G 7 . ? 59.522 60.531 -6.243 1.00 11.75 ? 2034 HOH A O 1 HETATM 8601 O O . HOH G 7 . ? 60.692 60.764 -3.614 1.00 11.50 ? 2035 HOH A O 1 HETATM 8602 O O . HOH G 7 . ? 60.754 58.165 -2.850 1.00 11.00 ? 2036 HOH A O 1 HETATM 8603 O O . HOH G 7 . ? 58.902 56.641 -1.454 1.00 11.63 ? 2037 HOH A O 1 HETATM 8604 O O . HOH G 7 . ? 60.524 54.653 -0.409 1.00 13.13 ? 2038 HOH A O 1 HETATM 8605 O O . HOH G 7 . ? 58.711 52.565 -0.133 1.00 12.58 ? 2039 HOH A O 1 HETATM 8606 O O . HOH G 7 . ? 56.091 53.301 -0.648 1.00 8.13 ? 2040 HOH A O 1 HETATM 8607 O O . HOH G 7 . ? 56.355 55.654 -2.140 1.00 10.17 ? 2041 HOH A O 1 HETATM 8608 O O . HOH G 7 . ? 55.000 57.487 -0.526 1.00 14.16 ? 2042 HOH A O 1 HETATM 8609 O O . HOH G 7 . ? 56.557 58.370 1.351 1.00 21.75 ? 2043 HOH A O 1 HETATM 8610 O O . HOH G 7 . ? 59.139 58.056 0.946 1.00 21.98 ? 2044 HOH A O 1 HETATM 8611 O O . HOH G 7 . ? 60.814 56.036 2.040 1.00 30.41 ? 2045 HOH A O 1 HETATM 8612 O O . HOH G 7 . ? 63.795 56.923 0.828 1.00 30.48 ? 2046 HOH A O 1 HETATM 8613 O O . HOH G 7 . ? 63.184 58.583 -1.464 1.00 15.67 ? 2047 HOH A O 1 HETATM 8614 O O . HOH G 7 . ? 64.868 59.195 -3.572 1.00 12.13 ? 2048 HOH A O 1 HETATM 8615 O O . HOH G 7 . ? 63.111 61.008 -4.843 1.00 12.82 ? 2049 HOH A O 1 HETATM 8616 O O . HOH G 7 . ? 60.498 62.158 -1.246 1.00 10.91 ? 2050 HOH A O 1 HETATM 8617 O O . HOH G 7 . ? 62.195 60.652 0.471 1.00 29.07 ? 2051 HOH A O 1 HETATM 8618 O O . HOH G 7 . ? 56.909 60.994 1.562 1.00 14.53 ? 2052 HOH A O 1 HETATM 8619 O O . HOH G 7 . ? 55.234 59.034 3.958 1.00 15.60 ? 2053 HOH A O 1 HETATM 8620 O O . HOH G 7 . ? 57.533 58.449 5.446 1.00 22.46 ? 2054 HOH A O 1 HETATM 8621 O O . HOH G 7 . ? 58.598 60.582 5.782 1.00 28.15 ? 2055 HOH A O 1 HETATM 8622 O O . HOH G 7 . ? 57.645 62.344 7.820 1.00 20.53 ? 2056 HOH A O 1 HETATM 8623 O O . HOH G 7 . ? 56.635 66.948 5.136 1.00 31.67 ? 2057 HOH A O 1 HETATM 8624 O O . HOH G 7 . ? 54.909 68.546 3.420 1.00 29.43 ? 2058 HOH A O 1 HETATM 8625 O O . HOH G 7 . ? 51.991 68.893 4.023 1.00 29.29 ? 2059 HOH A O 1 HETATM 8626 O O . HOH G 7 . ? 49.832 67.480 4.242 1.00 18.71 ? 2060 HOH A O 1 HETATM 8627 O O . HOH G 7 . ? 49.297 68.040 6.681 1.00 26.66 ? 2061 HOH A O 1 HETATM 8628 O O . HOH G 7 . ? 50.675 70.429 7.435 1.00 41.40 ? 2062 HOH A O 1 HETATM 8629 O O . HOH G 7 . ? 52.293 70.878 5.885 1.00 25.60 ? 2063 HOH A O 1 HETATM 8630 O O . HOH G 7 . ? 52.720 70.768 8.720 1.00 26.58 ? 2064 HOH A O 1 HETATM 8631 O O . HOH G 7 . ? 50.427 72.138 9.144 1.00 17.42 ? 2065 HOH A O 1 HETATM 8632 O O . HOH G 7 . ? 51.438 74.518 8.378 1.00 31.45 ? 2066 HOH A O 1 HETATM 8633 O O . HOH G 7 . ? 48.317 76.513 8.196 1.00 30.65 ? 2067 HOH A O 1 HETATM 8634 O O . HOH G 7 . ? 46.137 77.528 9.418 1.00 20.23 ? 2068 HOH A O 1 HETATM 8635 O O . HOH G 7 . ? 47.208 78.262 11.618 1.00 25.49 ? 2069 HOH A O 1 HETATM 8636 O O . HOH G 7 . ? 47.062 77.372 14.086 1.00 37.18 ? 2070 HOH A O 1 HETATM 8637 O O . HOH G 7 . ? 51.070 76.282 14.330 1.00 21.19 ? 2071 HOH A O 1 HETATM 8638 O O . HOH G 7 . ? 51.566 77.710 12.083 1.00 34.88 ? 2072 HOH A O 1 HETATM 8639 O O . HOH G 7 . ? 49.219 76.361 5.272 1.00 27.90 ? 2073 HOH A O 1 HETATM 8640 O O . HOH G 7 . ? 50.795 77.255 2.010 1.00 35.17 ? 2074 HOH A O 1 HETATM 8641 O O . HOH G 7 . ? 52.498 75.318 1.832 1.00 40.10 ? 2075 HOH A O 1 HETATM 8642 O O . HOH G 7 . ? 52.410 73.106 4.048 1.00 37.55 ? 2076 HOH A O 1 HETATM 8643 O O . HOH G 7 . ? 56.976 75.916 0.066 1.00 34.52 ? 2077 HOH A O 1 HETATM 8644 O O . HOH G 7 . ? 59.048 77.832 0.719 1.00 36.56 ? 2078 HOH A O 1 HETATM 8645 O O . HOH G 7 . ? 60.611 73.603 -0.354 1.00 49.69 ? 2079 HOH A O 1 HETATM 8646 O O . HOH G 7 . ? 59.843 71.196 0.120 1.00 36.90 ? 2080 HOH A O 1 HETATM 8647 O O . HOH G 7 . ? 59.260 68.169 2.411 1.00 20.91 ? 2081 HOH A O 1 HETATM 8648 O O . HOH G 7 . ? 52.998 67.956 9.013 1.00 27.05 ? 2082 HOH A O 1 HETATM 8649 O O . HOH G 7 . ? 51.211 66.345 8.437 1.00 23.87 ? 2083 HOH A O 1 HETATM 8650 O O . HOH G 7 . ? 55.484 67.540 13.227 1.00 25.51 ? 2084 HOH A O 1 HETATM 8651 O O . HOH G 7 . ? 57.500 68.726 13.543 1.00 35.66 ? 2085 HOH A O 1 HETATM 8652 O O . HOH G 7 . ? 61.331 63.751 14.657 1.00 35.69 ? 2086 HOH A O 1 HETATM 8653 O O . HOH G 7 . ? 61.577 59.510 14.550 1.00 32.27 ? 2087 HOH A O 1 HETATM 8654 O O . HOH G 7 . ? 61.173 57.080 15.577 1.00 33.10 ? 2088 HOH A O 1 HETATM 8655 O O . HOH G 7 . ? 58.978 50.986 14.804 1.00 40.97 ? 2089 HOH A O 1 HETATM 8656 O O . HOH G 7 . ? 57.685 49.378 16.627 1.00 28.87 ? 2090 HOH A O 1 HETATM 8657 O O . HOH G 7 . ? 55.252 50.142 16.836 1.00 28.67 ? 2091 HOH A O 1 HETATM 8658 O O . HOH G 7 . ? 54.319 47.667 15.627 1.00 23.51 ? 2092 HOH A O 1 HETATM 8659 O O . HOH G 7 . ? 56.835 46.633 15.813 1.00 28.44 ? 2093 HOH A O 1 HETATM 8660 O O . HOH G 7 . ? 57.318 48.974 21.255 1.00 23.50 ? 2094 HOH A O 1 HETATM 8661 O O . HOH G 7 . ? 56.860 47.347 23.253 1.00 36.21 ? 2095 HOH A O 1 HETATM 8662 O O . HOH G 7 . ? 58.746 51.135 22.081 1.00 21.90 ? 2096 HOH A O 1 HETATM 8663 O O . HOH G 7 . ? 60.241 50.775 20.209 1.00 35.58 ? 2097 HOH A O 1 HETATM 8664 O O . HOH G 7 . ? 59.623 50.931 24.750 1.00 32.32 ? 2098 HOH A O 1 HETATM 8665 O O . HOH G 7 . ? 58.116 52.705 26.152 1.00 35.37 ? 2099 HOH A O 1 HETATM 8666 O O . HOH G 7 . ? 55.838 51.971 27.294 1.00 31.71 ? 2100 HOH A O 1 HETATM 8667 O O . HOH G 7 . ? 53.340 52.636 26.240 1.00 29.52 ? 2101 HOH A O 1 HETATM 8668 O O . HOH G 7 . ? 51.895 50.406 27.486 1.00 28.58 ? 2102 HOH A O 1 HETATM 8669 O O . HOH G 7 . ? 52.360 49.123 25.640 1.00 28.84 ? 2103 HOH A O 1 HETATM 8670 O O . HOH G 7 . ? 49.151 49.831 28.366 1.00 16.97 ? 2104 HOH A O 1 HETATM 8671 O O . HOH G 7 . ? 49.878 47.254 28.938 1.00 24.79 ? 2105 HOH A O 1 HETATM 8672 O O . HOH G 7 . ? 49.505 45.528 30.938 1.00 24.75 ? 2106 HOH A O 1 HETATM 8673 O O . HOH G 7 . ? 46.477 43.770 28.499 1.00 37.21 ? 2107 HOH A O 1 HETATM 8674 O O . HOH G 7 . ? 47.322 45.856 26.762 1.00 31.48 ? 2108 HOH A O 1 HETATM 8675 O O . HOH G 7 . ? 44.151 45.307 25.423 1.00 32.82 ? 2109 HOH A O 1 HETATM 8676 O O . HOH G 7 . ? 45.677 45.006 23.020 1.00 31.80 ? 2110 HOH A O 1 HETATM 8677 O O . HOH G 7 . ? 43.917 44.925 19.237 1.00 40.19 ? 2111 HOH A O 1 HETATM 8678 O O . HOH G 7 . ? 46.209 46.091 16.318 1.00 32.63 ? 2112 HOH A O 1 HETATM 8679 O O . HOH G 7 . ? 48.058 48.278 16.480 1.00 15.82 ? 2113 HOH A O 1 HETATM 8680 O O . HOH G 7 . ? 48.010 49.496 13.848 1.00 11.66 ? 2114 HOH A O 1 HETATM 8681 O O . HOH G 7 . ? 47.026 48.596 11.525 1.00 15.81 ? 2115 HOH A O 1 HETATM 8682 O O . HOH G 7 . ? 46.681 45.825 11.655 1.00 29.02 ? 2116 HOH A O 1 HETATM 8683 O O . HOH G 7 . ? 48.448 44.775 10.240 1.00 33.85 ? 2117 HOH A O 1 HETATM 8684 O O . HOH G 7 . ? 51.022 45.287 10.248 1.00 29.43 ? 2118 HOH A O 1 HETATM 8685 O O . HOH G 7 . ? 50.006 43.935 7.072 1.00 18.08 ? 2119 HOH A O 1 HETATM 8686 O O . HOH G 7 . ? 49.126 41.808 8.347 1.00 26.85 ? 2120 HOH A O 1 HETATM 8687 O O . HOH G 7 . ? 46.558 42.882 9.718 1.00 29.39 ? 2121 HOH A O 1 HETATM 8688 O O . HOH G 7 . ? 44.481 40.853 7.753 1.00 37.48 ? 2122 HOH A O 1 HETATM 8689 O O . HOH G 7 . ? 42.450 39.381 7.770 1.00 35.38 ? 2123 HOH A O 1 HETATM 8690 O O . HOH G 7 . ? 40.138 39.135 9.239 1.00 25.09 ? 2124 HOH A O 1 HETATM 8691 O O . HOH G 7 . ? 40.053 35.298 11.388 1.00 23.17 ? 2125 HOH A O 1 HETATM 8692 O O . HOH G 7 . ? 37.184 33.840 5.602 1.00 42.70 ? 2126 HOH A O 1 HETATM 8693 O O . HOH G 7 . ? 34.611 36.208 3.424 1.00 32.37 ? 2127 HOH A O 1 HETATM 8694 O O . HOH G 7 . ? 37.157 37.474 3.023 1.00 28.01 ? 2128 HOH A O 1 HETATM 8695 O O . HOH G 7 . ? 38.295 39.975 1.756 1.00 12.25 ? 2129 HOH A O 1 HETATM 8696 O O . HOH G 7 . ? 39.934 39.623 -0.377 1.00 21.97 ? 2130 HOH A O 1 HETATM 8697 O O . HOH G 7 . ? 42.570 39.354 -1.398 1.00 24.07 ? 2131 HOH A O 1 HETATM 8698 O O . HOH G 7 . ? 44.518 41.714 -0.526 1.00 14.13 ? 2132 HOH A O 1 HETATM 8699 O O . HOH G 7 . ? 46.169 39.737 0.086 1.00 30.39 ? 2133 HOH A O 1 HETATM 8700 O O . HOH G 7 . ? 48.539 40.770 -1.001 1.00 22.67 ? 2134 HOH A O 1 HETATM 8701 O O . HOH G 7 . ? 49.722 41.032 1.388 1.00 35.84 ? 2135 HOH A O 1 HETATM 8702 O O . HOH G 7 . ? 48.147 41.653 3.671 1.00 18.82 ? 2136 HOH A O 1 HETATM 8703 O O . HOH G 7 . ? 47.690 40.083 6.001 1.00 32.37 ? 2137 HOH A O 1 HETATM 8704 O O . HOH G 7 . ? 49.362 44.121 4.429 1.00 14.52 ? 2138 HOH A O 1 HETATM 8705 O O . HOH G 7 . ? 51.696 44.375 3.037 1.00 20.56 ? 2139 HOH A O 1 HETATM 8706 O O . HOH G 7 . ? 51.820 46.399 1.239 1.00 11.90 ? 2140 HOH A O 1 HETATM 8707 O O . HOH G 7 . ? 49.791 48.383 1.371 1.00 9.25 ? 2141 HOH A O 1 HETATM 8708 O O . HOH G 7 . ? 47.489 45.956 3.641 1.00 11.04 ? 2142 HOH A O 1 HETATM 8709 O O . HOH G 7 . ? 47.457 42.820 -2.430 1.00 14.15 ? 2143 HOH A O 1 HETATM 8710 O O . HOH G 7 . ? 47.981 41.589 -5.279 1.00 27.66 ? 2144 HOH A O 1 HETATM 8711 O O . HOH G 7 . ? 48.715 44.131 -6.228 1.00 14.30 ? 2145 HOH A O 1 HETATM 8712 O O . HOH G 7 . ? 47.895 43.839 -8.710 1.00 19.59 ? 2146 HOH A O 1 HETATM 8713 O O . HOH G 7 . ? 45.546 42.027 -8.876 1.00 33.32 ? 2147 HOH A O 1 HETATM 8714 O O . HOH G 7 . ? 43.501 41.668 -7.665 1.00 23.42 ? 2148 HOH A O 1 HETATM 8715 O O . HOH G 7 . ? 42.273 40.476 -9.812 1.00 33.64 ? 2149 HOH A O 1 HETATM 8716 O O . HOH G 7 . ? 41.457 44.615 -6.872 1.00 13.76 ? 2150 HOH A O 1 HETATM 8717 O O . HOH G 7 . ? 36.683 44.771 -5.431 1.00 9.89 ? 2151 HOH A O 1 HETATM 8718 O O . HOH G 7 . ? 31.705 46.887 -8.073 1.00 8.22 ? 2152 HOH A O 1 HETATM 8719 O O . HOH G 7 . ? 33.433 48.000 -10.139 1.00 8.44 ? 2153 HOH A O 1 HETATM 8720 O O . HOH G 7 . ? 35.082 48.066 -16.457 1.00 31.53 ? 2154 HOH A O 1 HETATM 8721 O O . HOH G 7 . ? 35.069 50.401 -17.567 1.00 13.15 ? 2155 HOH A O 1 HETATM 8722 O O . HOH G 7 . ? 37.562 51.343 -18.554 1.00 16.39 ? 2156 HOH A O 1 HETATM 8723 O O . HOH G 7 . ? 37.571 51.987 -21.073 1.00 11.85 ? 2157 HOH A O 1 HETATM 8724 O O . HOH G 7 . ? 39.621 53.800 -20.760 1.00 14.28 ? 2158 HOH A O 1 HETATM 8725 O O . HOH G 7 . ? 40.140 56.137 -19.085 1.00 24.65 ? 2159 HOH A O 1 HETATM 8726 O O . HOH G 7 . ? 39.632 58.772 -18.011 1.00 16.92 ? 2160 HOH A O 1 HETATM 8727 O O . HOH G 7 . ? 41.630 58.537 -16.071 1.00 11.52 ? 2161 HOH A O 1 HETATM 8728 O O . HOH G 7 . ? 44.565 58.568 -15.964 1.00 13.01 ? 2162 HOH A O 1 HETATM 8729 O O . HOH G 7 . ? 44.471 55.948 -15.357 1.00 14.48 ? 2163 HOH A O 1 HETATM 8730 O O . HOH G 7 . ? 47.229 55.706 -15.465 1.00 14.55 ? 2164 HOH A O 1 HETATM 8731 O O . HOH G 7 . ? 46.614 57.132 -18.838 1.00 12.62 ? 2165 HOH A O 1 HETATM 8732 O O . HOH G 7 . ? 44.986 54.899 -18.320 1.00 26.54 ? 2166 HOH A O 1 HETATM 8733 O O . HOH G 7 . ? 45.895 52.634 -19.155 1.00 16.17 ? 2167 HOH A O 1 HETATM 8734 O O . HOH G 7 . ? 46.755 53.703 -21.461 1.00 25.37 ? 2168 HOH A O 1 HETATM 8735 O O . HOH G 7 . ? 48.700 54.777 -22.789 1.00 17.46 ? 2169 HOH A O 1 HETATM 8736 O O . HOH G 7 . ? 51.291 53.181 -23.956 1.00 11.39 ? 2170 HOH A O 1 HETATM 8737 O O . HOH G 7 . ? 50.999 52.662 -28.594 1.00 19.39 ? 2171 HOH A O 1 HETATM 8738 O O . HOH G 7 . ? 49.780 54.988 -29.139 1.00 18.73 ? 2172 HOH A O 1 HETATM 8739 O O . HOH G 7 . ? 52.097 56.240 -30.188 1.00 26.18 ? 2173 HOH A O 1 HETATM 8740 O O . HOH G 7 . ? 53.094 55.030 -31.955 1.00 32.78 ? 2174 HOH A O 1 HETATM 8741 O O . HOH G 7 . ? 53.239 53.225 -30.018 1.00 25.54 ? 2175 HOH A O 1 HETATM 8742 O O . HOH G 7 . ? 56.177 50.103 -30.439 1.00 43.48 ? 2176 HOH A O 1 HETATM 8743 O O . HOH G 7 . ? 59.955 52.865 -30.593 1.00 30.14 ? 2177 HOH A O 1 HETATM 8744 O O . HOH G 7 . ? 61.310 54.132 -28.890 1.00 23.36 ? 2178 HOH A O 1 HETATM 8745 O O . HOH G 7 . ? 64.671 55.758 -31.293 1.00 33.54 ? 2179 HOH A O 1 HETATM 8746 O O . HOH G 7 . ? 66.334 58.108 -31.201 1.00 36.20 ? 2180 HOH A O 1 HETATM 8747 O O . HOH G 7 . ? 66.785 59.808 -27.142 1.00 18.38 ? 2181 HOH A O 1 HETATM 8748 O O . HOH G 7 . ? 67.929 58.556 -24.101 1.00 18.34 ? 2182 HOH A O 1 HETATM 8749 O O . HOH G 7 . ? 66.625 56.099 -20.267 1.00 17.11 ? 2183 HOH A O 1 HETATM 8750 O O . HOH G 7 . ? 67.596 54.412 -18.392 1.00 22.16 ? 2184 HOH A O 1 HETATM 8751 O O . HOH G 7 . ? 69.815 53.691 -19.744 1.00 36.32 ? 2185 HOH A O 1 HETATM 8752 O O . HOH G 7 . ? 65.651 52.399 -21.090 1.00 38.40 ? 2186 HOH A O 1 HETATM 8753 O O . HOH G 7 . ? 64.406 49.476 -21.642 1.00 36.96 ? 2187 HOH A O 1 HETATM 8754 O O . HOH G 7 . ? 62.297 48.096 -20.925 1.00 37.64 ? 2188 HOH A O 1 HETATM 8755 O O . HOH G 7 . ? 60.843 46.684 -22.436 1.00 34.35 ? 2189 HOH A O 1 HETATM 8756 O O . HOH G 7 . ? 63.036 42.786 -20.917 1.00 26.36 ? 2190 HOH A O 1 HETATM 8757 O O . HOH G 7 . ? 57.039 43.053 -19.969 1.00 24.99 ? 2191 HOH A O 1 HETATM 8758 O O . HOH G 7 . ? 56.501 46.105 -17.439 1.00 16.36 ? 2192 HOH A O 1 HETATM 8759 O O . HOH G 7 . ? 57.146 39.023 -19.448 1.00 39.07 ? 2193 HOH A O 1 HETATM 8760 O O . HOH G 7 . ? 58.229 37.196 -18.025 1.00 40.67 ? 2194 HOH A O 1 HETATM 8761 O O . HOH G 7 . ? 59.337 37.571 -15.307 1.00 28.62 ? 2195 HOH A O 1 HETATM 8762 O O . HOH G 7 . ? 57.124 35.915 -14.341 1.00 31.92 ? 2196 HOH A O 1 HETATM 8763 O O . HOH G 7 . ? 58.434 34.710 -12.059 1.00 35.07 ? 2197 HOH A O 1 HETATM 8764 O O . HOH G 7 . ? 58.424 34.714 -6.009 1.00 34.48 ? 2198 HOH A O 1 HETATM 8765 O O . HOH G 7 . ? 64.413 39.285 -10.220 1.00 21.76 ? 2199 HOH A O 1 HETATM 8766 O O . HOH G 7 . ? 67.127 38.366 -9.541 1.00 27.59 ? 2200 HOH A O 1 HETATM 8767 O O . HOH G 7 . ? 63.506 44.547 -6.731 1.00 16.42 ? 2201 HOH A O 1 HETATM 8768 O O . HOH G 7 . ? 63.550 45.661 -3.026 1.00 42.57 ? 2202 HOH A O 1 HETATM 8769 O O . HOH G 7 . ? 66.069 45.348 -3.252 1.00 32.62 ? 2203 HOH A O 1 HETATM 8770 O O . HOH G 7 . ? 67.435 46.483 -1.386 1.00 23.44 ? 2204 HOH A O 1 HETATM 8771 O O . HOH G 7 . ? 68.160 49.245 -1.087 1.00 22.56 ? 2205 HOH A O 1 HETATM 8772 O O . HOH G 7 . ? 66.464 50.296 0.504 1.00 34.17 ? 2206 HOH A O 1 HETATM 8773 O O . HOH G 7 . ? 63.398 51.906 -0.295 1.00 31.08 ? 2207 HOH A O 1 HETATM 8774 O O . HOH G 7 . ? 59.300 49.907 -0.731 1.00 15.69 ? 2208 HOH A O 1 HETATM 8775 O O . HOH G 7 . ? 59.353 48.809 2.285 1.00 37.13 ? 2209 HOH A O 1 HETATM 8776 O O . HOH G 7 . ? 59.359 51.818 2.545 1.00 24.22 ? 2210 HOH A O 1 HETATM 8777 O O . HOH G 7 . ? 58.395 52.699 4.714 1.00 22.29 ? 2211 HOH A O 1 HETATM 8778 O O . HOH G 7 . ? 60.221 51.261 6.243 1.00 28.61 ? 2212 HOH A O 1 HETATM 8779 O O . HOH G 7 . ? 52.112 50.548 6.363 1.00 10.63 ? 2213 HOH A O 1 HETATM 8780 O O . HOH G 7 . ? 52.901 43.729 7.567 1.00 34.51 ? 2214 HOH A O 1 HETATM 8781 O O . HOH G 7 . ? 57.927 42.199 1.589 1.00 22.74 ? 2215 HOH A O 1 HETATM 8782 O O . HOH G 7 . ? 58.894 46.235 -1.461 1.00 21.41 ? 2216 HOH A O 1 HETATM 8783 O O . HOH G 7 . ? 60.993 45.216 -3.782 1.00 30.67 ? 2217 HOH A O 1 HETATM 8784 O O . HOH G 7 . ? 51.008 44.160 -8.020 1.00 11.45 ? 2218 HOH A O 1 HETATM 8785 O O . HOH G 7 . ? 51.856 40.896 -13.033 1.00 31.51 ? 2219 HOH A O 1 HETATM 8786 O O . HOH G 7 . ? 47.159 41.277 -14.816 1.00 27.87 ? 2220 HOH A O 1 HETATM 8787 O O . HOH G 7 . ? 42.514 39.236 -15.685 1.00 25.62 ? 2221 HOH A O 1 HETATM 8788 O O . HOH G 7 . ? 41.513 41.033 -17.525 1.00 16.99 ? 2222 HOH A O 1 HETATM 8789 O O . HOH G 7 . ? 40.879 40.635 -21.508 1.00 23.99 ? 2223 HOH A O 1 HETATM 8790 O O . HOH G 7 . ? 38.666 42.062 -22.152 1.00 25.59 ? 2224 HOH A O 1 HETATM 8791 O O . HOH G 7 . ? 36.867 41.056 -24.687 1.00 27.74 ? 2225 HOH A O 1 HETATM 8792 O O . HOH G 7 . ? 37.279 45.008 -25.368 1.00 20.34 ? 2226 HOH A O 1 HETATM 8793 O O . HOH G 7 . ? 35.485 45.010 -27.389 1.00 15.62 ? 2227 HOH A O 1 HETATM 8794 O O . HOH G 7 . ? 40.793 47.978 -29.259 1.00 31.81 ? 2228 HOH A O 1 HETATM 8795 O O . HOH G 7 . ? 42.642 47.304 -27.299 1.00 29.25 ? 2229 HOH A O 1 HETATM 8796 O O . HOH G 7 . ? 42.121 47.138 -24.528 1.00 13.69 ? 2230 HOH A O 1 HETATM 8797 O O . HOH G 7 . ? 41.406 44.584 -24.317 1.00 20.39 ? 2231 HOH A O 1 HETATM 8798 O O . HOH G 7 . ? 43.302 40.311 -23.045 1.00 33.81 ? 2232 HOH A O 1 HETATM 8799 O O . HOH G 7 . ? 46.997 46.142 -26.501 1.00 36.04 ? 2233 HOH A O 1 HETATM 8800 O O . HOH G 7 . ? 47.226 47.615 -28.728 1.00 31.75 ? 2234 HOH A O 1 HETATM 8801 O O . HOH G 7 . ? 48.451 49.665 -29.194 1.00 24.26 ? 2235 HOH A O 1 HETATM 8802 O O . HOH G 7 . ? 49.261 51.477 -30.306 1.00 34.79 ? 2236 HOH A O 1 HETATM 8803 O O . HOH G 7 . ? 47.848 49.571 -31.520 1.00 39.72 ? 2237 HOH A O 1 HETATM 8804 O O . HOH G 7 . ? 49.986 46.720 -30.508 1.00 43.44 ? 2238 HOH A O 1 HETATM 8805 O O . HOH G 7 . ? 52.184 45.119 -27.281 1.00 34.63 ? 2239 HOH A O 1 HETATM 8806 O O . HOH G 7 . ? 53.272 46.973 -25.199 1.00 18.12 ? 2240 HOH A O 1 HETATM 8807 O O . HOH G 7 . ? 58.418 43.928 -28.116 1.00 34.47 ? 2241 HOH A O 1 HETATM 8808 O O . HOH G 7 . ? 58.768 53.523 -22.249 1.00 21.18 ? 2242 HOH A O 1 HETATM 8809 O O . HOH G 7 . ? 60.390 60.828 -18.155 1.00 10.05 ? 2243 HOH A O 1 HETATM 8810 O O . HOH G 7 . ? 53.672 64.697 -19.860 1.00 7.98 ? 2244 HOH A O 1 HETATM 8811 O O . HOH G 7 . ? 53.175 70.583 -17.407 1.00 29.74 ? 2245 HOH A O 1 HETATM 8812 O O . HOH G 7 . ? 53.535 72.423 -19.334 1.00 14.24 ? 2246 HOH A O 1 HETATM 8813 O O . HOH G 7 . ? 51.240 71.225 -20.379 1.00 18.70 ? 2247 HOH A O 1 HETATM 8814 O O . HOH G 7 . ? 49.914 73.365 -21.765 1.00 26.89 ? 2248 HOH A O 1 HETATM 8815 O O . HOH G 7 . ? 47.517 71.732 -20.265 1.00 24.40 ? 2249 HOH A O 1 HETATM 8816 O O . HOH G 7 . ? 46.935 72.202 -17.485 1.00 21.65 ? 2250 HOH A O 1 HETATM 8817 O O . HOH G 7 . ? 45.562 69.853 -18.509 1.00 35.59 ? 2251 HOH A O 1 HETATM 8818 O O . HOH G 7 . ? 46.408 67.528 -15.673 1.00 13.76 ? 2252 HOH A O 1 HETATM 8819 O O . HOH G 7 . ? 50.008 70.663 -17.771 1.00 26.40 ? 2253 HOH A O 1 HETATM 8820 O O . HOH G 7 . ? 51.038 70.762 -23.830 1.00 17.61 ? 2254 HOH A O 1 HETATM 8821 O O . HOH G 7 . ? 50.490 73.554 -25.519 1.00 19.47 ? 2255 HOH A O 1 HETATM 8822 O O . HOH G 7 . ? 54.913 80.881 -23.700 1.00 12.37 ? 2256 HOH A O 1 HETATM 8823 O O . HOH G 7 . ? 55.142 80.340 -19.433 1.00 22.02 ? 2257 HOH A O 1 HETATM 8824 O O . HOH G 7 . ? 57.262 80.092 -17.987 1.00 37.86 ? 2258 HOH A O 1 HETATM 8825 O O . HOH G 7 . ? 55.598 81.848 -16.421 1.00 33.33 ? 2259 HOH A O 1 HETATM 8826 O O . HOH G 7 . ? 56.023 78.597 -14.705 1.00 33.27 ? 2260 HOH A O 1 HETATM 8827 O O . HOH G 7 . ? 52.922 76.071 -14.248 1.00 37.39 ? 2261 HOH A O 1 HETATM 8828 O O . HOH G 7 . ? 52.526 76.376 -11.827 1.00 38.02 ? 2262 HOH A O 1 HETATM 8829 O O . HOH G 7 . ? 50.095 79.574 -11.379 1.00 41.36 ? 2263 HOH A O 1 HETATM 8830 O O . HOH G 7 . ? 48.380 77.875 -9.797 1.00 25.49 ? 2264 HOH A O 1 HETATM 8831 O O . HOH G 7 . ? 45.744 79.031 -7.964 1.00 24.29 ? 2265 HOH A O 1 HETATM 8832 O O . HOH G 7 . ? 48.149 80.137 -4.354 1.00 39.13 ? 2266 HOH A O 1 HETATM 8833 O O . HOH G 7 . ? 50.057 81.167 -3.047 1.00 38.66 ? 2267 HOH A O 1 HETATM 8834 O O . HOH G 7 . ? 51.225 79.326 -1.875 1.00 23.27 ? 2268 HOH A O 1 HETATM 8835 O O . HOH G 7 . ? 51.738 79.986 0.709 1.00 34.91 ? 2269 HOH A O 1 HETATM 8836 O O . HOH G 7 . ? 46.531 82.617 -0.721 1.00 32.61 ? 2270 HOH A O 1 HETATM 8837 O O . HOH G 7 . ? 40.994 81.603 -3.478 1.00 45.68 ? 2271 HOH A O 1 HETATM 8838 O O . HOH G 7 . ? 38.721 80.166 -3.256 1.00 25.89 ? 2272 HOH A O 1 HETATM 8839 O O . HOH G 7 . ? 37.692 80.345 -0.675 1.00 16.71 ? 2273 HOH A O 1 HETATM 8840 O O . HOH G 7 . ? 38.142 83.113 -0.978 1.00 23.83 ? 2274 HOH A O 1 HETATM 8841 O O . HOH G 7 . ? 37.229 83.543 -4.142 1.00 26.68 ? 2275 HOH A O 1 HETATM 8842 O O . HOH G 7 . ? 35.089 85.106 -1.000 1.00 36.77 ? 2276 HOH A O 1 HETATM 8843 O O . HOH G 7 . ? 32.988 84.221 0.320 1.00 26.08 ? 2277 HOH A O 1 HETATM 8844 O O . HOH G 7 . ? 31.409 81.701 0.536 1.00 16.30 ? 2278 HOH A O 1 HETATM 8845 O O . HOH G 7 . ? 29.874 83.027 2.542 1.00 17.72 ? 2279 HOH A O 1 HETATM 8846 O O . HOH G 7 . ? 27.578 82.397 3.617 1.00 22.42 ? 2280 HOH A O 1 HETATM 8847 O O . HOH G 7 . ? 24.787 83.782 2.513 1.00 27.07 ? 2281 HOH A O 1 HETATM 8848 O O . HOH G 7 . ? 21.791 79.597 5.470 1.00 24.32 ? 2282 HOH A O 1 HETATM 8849 O O . HOH G 7 . ? 19.270 76.328 4.827 1.00 23.89 ? 2283 HOH A O 1 HETATM 8850 O O . HOH G 7 . ? 17.717 74.289 3.985 1.00 18.96 ? 2284 HOH A O 1 HETATM 8851 O O . HOH G 7 . ? 15.695 73.418 5.469 1.00 24.71 ? 2285 HOH A O 1 HETATM 8852 O O . HOH G 7 . ? 15.725 70.018 6.348 1.00 27.60 ? 2286 HOH A O 1 HETATM 8853 O O . HOH G 7 . ? 17.880 70.744 6.644 1.00 27.55 ? 2287 HOH A O 1 HETATM 8854 O O . HOH G 7 . ? 18.667 69.843 4.250 1.00 13.49 ? 2288 HOH A O 1 HETATM 8855 O O . HOH G 7 . ? 19.298 72.272 3.068 1.00 14.73 ? 2289 HOH A O 1 HETATM 8856 O O . HOH G 7 . ? 16.927 74.399 -2.994 1.00 13.25 ? 2290 HOH A O 1 HETATM 8857 O O . HOH G 7 . ? 20.133 74.184 -6.706 1.00 12.18 ? 2291 HOH A O 1 HETATM 8858 O O . HOH G 7 . ? 24.615 70.455 -8.730 1.00 10.69 ? 2292 HOH A O 1 HETATM 8859 O O . HOH G 7 . ? 26.757 68.788 -9.219 1.00 8.47 ? 2293 HOH A O 1 HETATM 8860 O O . HOH G 7 . ? 32.599 64.497 -9.974 1.00 15.58 ? 2294 HOH A O 1 HETATM 8861 O O . HOH G 7 . ? 34.238 58.439 -8.764 1.00 7.71 ? 2295 HOH A O 1 HETATM 8862 O O . HOH G 7 . ? 30.158 58.304 -11.768 1.00 7.43 ? 2296 HOH A O 1 HETATM 8863 O O . HOH G 7 . ? 24.691 52.763 -11.720 1.00 8.57 ? 2297 HOH A O 1 HETATM 8864 O O . HOH G 7 . ? 22.298 54.274 -12.020 1.00 9.59 ? 2298 HOH A O 1 HETATM 8865 O O . HOH G 7 . ? 19.641 53.347 -11.794 1.00 9.89 ? 2299 HOH A O 1 HETATM 8866 O O . HOH G 7 . ? 18.575 50.861 -12.426 1.00 11.57 ? 2300 HOH A O 1 HETATM 8867 O O . HOH G 7 . ? 22.892 51.606 -8.729 1.00 15.09 ? 2301 HOH A O 1 HETATM 8868 O O . HOH G 7 . ? 25.509 51.053 -9.469 1.00 11.58 ? 2302 HOH A O 1 HETATM 8869 O O . HOH G 7 . ? 26.257 48.757 -10.941 1.00 9.46 ? 2303 HOH A O 1 HETATM 8870 O O . HOH G 7 . ? 26.039 49.487 -13.675 1.00 8.93 ? 2304 HOH A O 1 HETATM 8871 O O . HOH G 7 . ? 28.823 42.614 -11.935 1.00 11.04 ? 2305 HOH A O 1 HETATM 8872 O O . HOH G 7 . ? 26.662 41.437 -13.207 1.00 13.11 ? 2306 HOH A O 1 HETATM 8873 O O . HOH G 7 . ? 24.470 38.946 -11.483 1.00 19.74 ? 2307 HOH A O 1 HETATM 8874 O O . HOH G 7 . ? 22.773 36.634 -9.688 1.00 39.57 ? 2308 HOH A O 1 HETATM 8875 O O . HOH G 7 . ? 21.788 40.176 -8.605 1.00 22.30 ? 2309 HOH A O 1 HETATM 8876 O O . HOH G 7 . ? 20.692 42.564 -7.319 1.00 17.13 ? 2310 HOH A O 1 HETATM 8877 O O . HOH G 7 . ? 19.711 41.441 -4.945 1.00 21.97 ? 2311 HOH A O 1 HETATM 8878 O O . HOH G 7 . ? 19.158 42.292 -2.530 1.00 25.71 ? 2312 HOH A O 1 HETATM 8879 O O . HOH G 7 . ? 16.578 42.760 -2.254 1.00 26.38 ? 2313 HOH A O 1 HETATM 8880 O O . HOH G 7 . ? 18.634 39.170 -2.573 1.00 34.93 ? 2314 HOH A O 1 HETATM 8881 O O . HOH G 7 . ? 17.845 37.673 -0.093 1.00 37.22 ? 2315 HOH A O 1 HETATM 8882 O O . HOH G 7 . ? 21.984 36.708 0.342 1.00 21.20 ? 2316 HOH A O 1 HETATM 8883 O O . HOH G 7 . ? 24.611 34.180 0.329 1.00 43.72 ? 2317 HOH A O 1 HETATM 8884 O O . HOH G 7 . ? 27.059 33.655 -3.191 1.00 35.02 ? 2318 HOH A O 1 HETATM 8885 O O . HOH G 7 . ? 29.962 34.048 -1.486 1.00 25.57 ? 2319 HOH A O 1 HETATM 8886 O O . HOH G 7 . ? 32.135 34.216 -3.247 1.00 20.36 ? 2320 HOH A O 1 HETATM 8887 O O . HOH G 7 . ? 33.224 36.517 -4.339 1.00 13.96 ? 2321 HOH A O 1 HETATM 8888 O O . HOH G 7 . ? 32.326 38.999 -4.886 1.00 10.69 ? 2322 HOH A O 1 HETATM 8889 O O . HOH G 7 . ? 35.948 35.913 -4.506 1.00 18.88 ? 2323 HOH A O 1 HETATM 8890 O O . HOH G 7 . ? 39.852 38.665 -3.531 1.00 21.30 ? 2324 HOH A O 1 HETATM 8891 O O . HOH G 7 . ? 30.441 34.530 -9.639 1.00 28.87 ? 2325 HOH A O 1 HETATM 8892 O O . HOH G 7 . ? 30.223 34.997 -12.353 1.00 19.63 ? 2326 HOH A O 1 HETATM 8893 O O . HOH G 7 . ? 28.058 35.138 -6.709 1.00 21.92 ? 2327 HOH A O 1 HETATM 8894 O O . HOH G 7 . ? 25.242 34.421 -7.096 1.00 39.22 ? 2328 HOH A O 1 HETATM 8895 O O . HOH G 7 . ? 21.446 35.225 -5.302 1.00 33.78 ? 2329 HOH A O 1 HETATM 8896 O O . HOH G 7 . ? 18.047 36.746 5.812 1.00 38.08 ? 2330 HOH A O 1 HETATM 8897 O O . HOH G 7 . ? 17.266 41.507 9.362 1.00 27.75 ? 2331 HOH A O 1 HETATM 8898 O O . HOH G 7 . ? 12.945 42.424 12.762 1.00 17.97 ? 2332 HOH A O 1 HETATM 8899 O O . HOH G 7 . ? 10.342 41.660 12.292 1.00 34.85 ? 2333 HOH A O 1 HETATM 8900 O O . HOH G 7 . ? 8.747 44.353 13.213 1.00 28.05 ? 2334 HOH A O 1 HETATM 8901 O O . HOH G 7 . ? 8.030 47.983 12.006 1.00 24.48 ? 2335 HOH A O 1 HETATM 8902 O O . HOH G 7 . ? 7.064 51.216 9.213 1.00 43.25 ? 2336 HOH A O 1 HETATM 8903 O O . HOH G 7 . ? 9.023 50.247 8.102 1.00 26.76 ? 2337 HOH A O 1 HETATM 8904 O O . HOH G 7 . ? 8.582 49.274 5.628 1.00 45.44 ? 2338 HOH A O 1 HETATM 8905 O O . HOH G 7 . ? 10.438 51.512 2.412 1.00 28.51 ? 2339 HOH A O 1 HETATM 8906 O O . HOH G 7 . ? 10.891 53.477 4.115 1.00 24.12 ? 2340 HOH A O 1 HETATM 8907 O O . HOH G 7 . ? 11.300 53.007 6.922 1.00 16.43 ? 2341 HOH A O 1 HETATM 8908 O O . HOH G 7 . ? 12.433 56.149 5.415 1.00 14.88 ? 2342 HOH A O 1 HETATM 8909 O O . HOH G 7 . ? 13.829 53.996 4.413 1.00 13.01 ? 2343 HOH A O 1 HETATM 8910 O O . HOH G 7 . ? 13.426 53.320 1.840 1.00 16.84 ? 2344 HOH A O 1 HETATM 8911 O O . HOH G 7 . ? 14.364 50.527 0.978 1.00 20.39 ? 2345 HOH A O 1 HETATM 8912 O O . HOH G 7 . ? 13.401 48.163 1.672 1.00 27.98 ? 2346 HOH A O 1 HETATM 8913 O O . HOH G 7 . ? 13.321 50.619 -1.581 1.00 21.00 ? 2347 HOH A O 1 HETATM 8914 O O . HOH G 7 . ? 11.617 48.051 -2.379 1.00 32.71 ? 2348 HOH A O 1 HETATM 8915 O O . HOH G 7 . ? 9.460 47.597 -8.713 1.00 38.54 ? 2349 HOH A O 1 HETATM 8916 O O . HOH G 7 . ? 7.994 52.704 -7.541 1.00 38.30 ? 2350 HOH A O 1 HETATM 8917 O O . HOH G 7 . ? 8.702 54.740 -6.092 1.00 22.69 ? 2351 HOH A O 1 HETATM 8918 O O . HOH G 7 . ? 8.608 57.478 -6.816 1.00 21.56 ? 2352 HOH A O 1 HETATM 8919 O O . HOH G 7 . ? 10.016 57.731 -3.306 1.00 29.37 ? 2353 HOH A O 1 HETATM 8920 O O . HOH G 7 . ? 11.704 59.302 -4.973 1.00 18.74 ? 2354 HOH A O 1 HETATM 8921 O O . HOH G 7 . ? 14.038 59.592 -3.358 1.00 12.84 ? 2355 HOH A O 1 HETATM 8922 O O . HOH G 7 . ? 13.905 57.843 -1.337 1.00 17.30 ? 2356 HOH A O 1 HETATM 8923 O O . HOH G 7 . ? 12.938 61.826 -2.259 1.00 21.93 ? 2357 HOH A O 1 HETATM 8924 O O . HOH G 7 . ? 11.491 61.429 0.043 1.00 40.08 ? 2358 HOH A O 1 HETATM 8925 O O . HOH G 7 . ? 10.321 62.061 1.910 1.00 33.39 ? 2359 HOH A O 1 HETATM 8926 O O . HOH G 7 . ? 11.266 62.020 5.265 1.00 30.45 ? 2360 HOH A O 1 HETATM 8927 O O . HOH G 7 . ? 13.172 62.792 6.714 1.00 37.90 ? 2361 HOH A O 1 HETATM 8928 O O . HOH G 7 . ? 13.641 60.562 7.738 1.00 23.50 ? 2362 HOH A O 1 HETATM 8929 O O . HOH G 7 . ? 14.425 59.873 5.152 1.00 12.56 ? 2363 HOH A O 1 HETATM 8930 O O . HOH G 7 . ? 11.567 58.587 7.878 1.00 25.31 ? 2364 HOH A O 1 HETATM 8931 O O . HOH G 7 . ? 9.762 59.660 6.599 1.00 32.08 ? 2365 HOH A O 1 HETATM 8932 O O . HOH G 7 . ? 5.362 57.025 6.991 1.00 32.78 ? 2366 HOH A O 1 HETATM 8933 O O . HOH G 7 . ? 6.854 59.552 2.339 1.00 51.96 ? 2367 HOH A O 1 HETATM 8934 O O . HOH G 7 . ? 7.755 58.108 0.055 1.00 35.54 ? 2368 HOH A O 1 HETATM 8935 O O . HOH G 7 . ? 11.022 62.385 -4.463 1.00 34.16 ? 2369 HOH A O 1 HETATM 8936 O O . HOH G 7 . ? 13.156 66.687 -4.752 1.00 13.79 ? 2370 HOH A O 1 HETATM 8937 O O . HOH G 7 . ? 14.080 68.103 -7.719 1.00 16.43 ? 2371 HOH A O 1 HETATM 8938 O O . HOH G 7 . ? 13.718 69.884 -9.573 1.00 19.85 ? 2372 HOH A O 1 HETATM 8939 O O . HOH G 7 . ? 11.383 70.740 -7.899 1.00 30.48 ? 2373 HOH A O 1 HETATM 8940 O O . HOH G 7 . ? 12.680 66.169 -9.608 1.00 16.90 ? 2374 HOH A O 1 HETATM 8941 O O . HOH G 7 . ? 10.329 64.506 -10.201 1.00 40.32 ? 2375 HOH A O 1 HETATM 8942 O O . HOH G 7 . ? 12.223 64.434 -12.353 1.00 24.47 ? 2376 HOH A O 1 HETATM 8943 O O . HOH G 7 . ? 14.241 62.706 -12.079 1.00 16.70 ? 2377 HOH A O 1 HETATM 8944 O O . HOH G 7 . ? 14.584 61.750 -14.544 1.00 18.69 ? 2378 HOH A O 1 HETATM 8945 O O . HOH G 7 . ? 14.359 63.792 -16.344 1.00 15.26 ? 2379 HOH A O 1 HETATM 8946 O O . HOH G 7 . ? 11.681 63.479 -16.828 1.00 19.22 ? 2380 HOH A O 1 HETATM 8947 O O . HOH G 7 . ? 10.118 62.928 -14.602 1.00 30.99 ? 2381 HOH A O 1 HETATM 8948 O O . HOH G 7 . ? 8.515 65.101 -14.619 1.00 21.99 ? 2382 HOH A O 1 HETATM 8949 O O . HOH G 7 . ? 11.398 61.187 -18.381 1.00 18.69 ? 2383 HOH A O 1 HETATM 8950 O O . HOH G 7 . ? 13.349 62.209 -19.954 1.00 16.94 ? 2384 HOH A O 1 HETATM 8951 O O . HOH G 7 . ? 13.807 60.677 -22.440 1.00 15.60 ? 2385 HOH A O 1 HETATM 8952 O O . HOH G 7 . ? 12.892 61.807 -24.968 1.00 29.67 ? 2386 HOH A O 1 HETATM 8953 O O . HOH G 7 . ? 14.889 63.451 -25.832 1.00 24.92 ? 2387 HOH A O 1 HETATM 8954 O O . HOH G 7 . ? 14.631 64.485 -28.885 1.00 35.95 ? 2388 HOH A O 1 HETATM 8955 O O . HOH G 7 . ? 16.605 62.866 -29.552 1.00 38.94 ? 2389 HOH A O 1 HETATM 8956 O O . HOH G 7 . ? 16.646 60.490 -28.124 1.00 19.96 ? 2390 HOH A O 1 HETATM 8957 O O . HOH G 7 . ? 18.463 64.831 -26.997 1.00 19.59 ? 2391 HOH A O 1 HETATM 8958 O O . HOH G 7 . ? 17.076 67.067 -26.003 1.00 25.82 ? 2392 HOH A O 1 HETATM 8959 O O . HOH G 7 . ? 17.216 69.935 -23.334 1.00 15.62 ? 2393 HOH A O 1 HETATM 8960 O O . HOH G 7 . ? 14.546 70.337 -22.905 1.00 24.35 ? 2394 HOH A O 1 HETATM 8961 O O . HOH G 7 . ? 13.086 69.916 -24.924 1.00 41.25 ? 2395 HOH A O 1 HETATM 8962 O O . HOH G 7 . ? 12.767 74.251 -23.026 1.00 37.18 ? 2396 HOH A O 1 HETATM 8963 O O . HOH G 7 . ? 14.903 73.540 -21.789 1.00 31.58 ? 2397 HOH A O 1 HETATM 8964 O O . HOH G 7 . ? 16.202 74.779 -23.988 1.00 38.82 ? 2398 HOH A O 1 HETATM 8965 O O . HOH G 7 . ? 17.122 74.242 -28.714 1.00 46.14 ? 2399 HOH A O 1 HETATM 8966 O O . HOH G 7 . ? 18.156 76.260 -29.587 1.00 45.11 ? 2400 HOH A O 1 HETATM 8967 O O . HOH G 7 . ? 18.215 73.210 -31.231 1.00 36.27 ? 2401 HOH A O 1 HETATM 8968 O O . HOH G 7 . ? 18.572 70.552 -29.976 1.00 33.91 ? 2402 HOH A O 1 HETATM 8969 O O . HOH G 7 . ? 20.765 68.640 -31.543 1.00 32.84 ? 2403 HOH A O 1 HETATM 8970 O O . HOH G 7 . ? 16.894 69.979 -33.694 1.00 45.04 ? 2404 HOH A O 1 HETATM 8971 O O . HOH G 7 . ? 17.088 72.761 -34.070 1.00 37.57 ? 2405 HOH A O 1 HETATM 8972 O O . HOH G 7 . ? 30.207 74.716 -29.240 1.00 12.61 ? 2406 HOH A O 1 HETATM 8973 O O . HOH G 7 . ? 32.335 77.474 -29.697 1.00 13.41 ? 2407 HOH A O 1 HETATM 8974 O O . HOH G 7 . ? 28.891 81.682 -35.657 1.00 17.13 ? 2408 HOH A O 1 HETATM 8975 O O . HOH G 7 . ? 28.075 84.348 -35.548 1.00 15.55 ? 2409 HOH A O 1 HETATM 8976 O O . HOH G 7 . ? 23.240 88.503 -38.356 1.00 32.43 ? 2410 HOH A O 1 HETATM 8977 O O . HOH G 7 . ? 25.852 87.412 -42.960 1.00 39.56 ? 2411 HOH A O 1 HETATM 8978 O O . HOH G 7 . ? 28.346 87.584 -41.752 1.00 29.38 ? 2412 HOH A O 1 HETATM 8979 O O . HOH G 7 . ? 28.329 90.354 -42.770 1.00 26.78 ? 2413 HOH A O 1 HETATM 8980 O O . HOH G 7 . ? 32.545 88.893 -43.284 1.00 24.98 ? 2414 HOH A O 1 HETATM 8981 O O . HOH G 7 . ? 34.046 86.608 -43.746 1.00 42.47 ? 2415 HOH A O 1 HETATM 8982 O O . HOH G 7 . ? 38.921 86.314 -41.597 1.00 30.52 ? 2416 HOH A O 1 HETATM 8983 O O . HOH G 7 . ? 42.128 87.563 -41.039 1.00 14.39 ? 2417 HOH A O 1 HETATM 8984 O O . HOH G 7 . ? 43.648 88.202 -38.767 1.00 14.90 ? 2418 HOH A O 1 HETATM 8985 O O . HOH G 7 . ? 43.496 93.658 -37.740 1.00 19.62 ? 2419 HOH A O 1 HETATM 8986 O O . HOH G 7 . ? 41.244 94.691 -39.574 1.00 25.50 ? 2420 HOH A O 1 HETATM 8987 O O . HOH G 7 . ? 40.789 96.225 -37.509 1.00 24.17 ? 2421 HOH A O 1 HETATM 8988 O O . HOH G 7 . ? 43.069 97.978 -37.319 1.00 33.26 ? 2422 HOH A O 1 HETATM 8989 O O . HOH G 7 . ? 46.893 95.357 -37.059 1.00 38.25 ? 2423 HOH A O 1 HETATM 8990 O O . HOH G 7 . ? 48.699 97.694 -33.723 1.00 32.10 ? 2424 HOH A O 1 HETATM 8991 O O . HOH G 7 . ? 47.348 99.643 -32.731 1.00 33.08 ? 2425 HOH A O 1 HETATM 8992 O O . HOH G 7 . ? 42.095 101.031 -32.230 1.00 36.04 ? 2426 HOH A O 1 HETATM 8993 O O . HOH G 7 . ? 40.121 99.814 -32.019 1.00 29.57 ? 2427 HOH A O 1 HETATM 8994 O O . HOH G 7 . ? 37.738 97.348 -30.851 1.00 49.00 ? 2428 HOH A O 1 HETATM 8995 O O . HOH G 7 . ? 35.134 94.770 -32.373 1.00 26.37 ? 2429 HOH A O 1 HETATM 8996 O O . HOH G 7 . ? 35.993 93.454 -30.044 1.00 33.39 ? 2430 HOH A O 1 HETATM 8997 O O . HOH G 7 . ? 42.582 94.219 -30.337 1.00 39.95 ? 2431 HOH A O 1 HETATM 8998 O O . HOH G 7 . ? 44.362 95.558 -30.497 1.00 36.04 ? 2432 HOH A O 1 HETATM 8999 O O . HOH G 7 . ? 45.152 92.555 -25.520 1.00 29.71 ? 2433 HOH A O 1 HETATM 9000 O O . HOH G 7 . ? 45.039 89.753 -25.584 1.00 18.82 ? 2434 HOH A O 1 HETATM 9001 O O . HOH G 7 . ? 47.001 89.404 -23.810 1.00 29.32 ? 2435 HOH A O 1 HETATM 9002 O O . HOH G 7 . ? 49.340 91.699 -24.590 1.00 32.66 ? 2436 HOH A O 1 HETATM 9003 O O . HOH G 7 . ? 52.678 91.711 -23.599 1.00 31.04 ? 2437 HOH A O 1 HETATM 9004 O O . HOH G 7 . ? 54.847 89.966 -23.795 1.00 24.78 ? 2438 HOH A O 1 HETATM 9005 O O . HOH G 7 . ? 56.190 90.769 -25.891 1.00 22.96 ? 2439 HOH A O 1 HETATM 9006 O O . HOH G 7 . ? 57.621 93.210 -25.136 1.00 33.57 ? 2440 HOH A O 1 HETATM 9007 O O . HOH G 7 . ? 58.565 93.214 -27.340 1.00 36.11 ? 2441 HOH A O 1 HETATM 9008 O O . HOH G 7 . ? 60.326 91.749 -28.510 1.00 26.40 ? 2442 HOH A O 1 HETATM 9009 O O . HOH G 7 . ? 60.321 91.053 -31.323 1.00 29.30 ? 2443 HOH A O 1 HETATM 9010 O O . HOH G 7 . ? 59.620 90.906 -35.511 1.00 20.63 ? 2444 HOH A O 1 HETATM 9011 O O . HOH G 7 . ? 61.445 90.643 -37.162 1.00 30.68 ? 2445 HOH A O 1 HETATM 9012 O O . HOH G 7 . ? 60.447 92.977 -38.309 1.00 38.27 ? 2446 HOH A O 1 HETATM 9013 O O . HOH G 7 . ? 58.453 91.975 -42.598 1.00 51.13 ? 2447 HOH A O 1 HETATM 9014 O O . HOH G 7 . ? 56.616 89.666 -43.770 1.00 31.97 ? 2448 HOH A O 1 HETATM 9015 O O . HOH G 7 . ? 53.928 90.544 -43.135 1.00 36.90 ? 2449 HOH A O 1 HETATM 9016 O O . HOH G 7 . ? 53.679 92.851 -40.243 1.00 35.10 ? 2450 HOH A O 1 HETATM 9017 O O . HOH G 7 . ? 53.944 93.807 -33.029 1.00 43.09 ? 2451 HOH A O 1 HETATM 9018 O O . HOH G 7 . ? 56.450 92.687 -29.791 1.00 26.24 ? 2452 HOH A O 1 HETATM 9019 O O . HOH G 7 . ? 56.409 89.795 -21.333 1.00 31.65 ? 2453 HOH A O 1 HETATM 9020 O O . HOH G 7 . ? 56.930 87.495 -20.168 1.00 27.41 ? 2454 HOH A O 1 HETATM 9021 O O . HOH G 7 . ? 53.157 86.658 -21.420 1.00 24.26 ? 2455 HOH A O 1 HETATM 9022 O O . HOH G 7 . ? 49.011 84.080 -19.588 1.00 36.96 ? 2456 HOH A O 1 HETATM 9023 O O . HOH G 7 . ? 47.103 83.106 -21.020 1.00 40.11 ? 2457 HOH A O 1 HETATM 9024 O O . HOH G 7 . ? 47.266 81.324 -17.192 1.00 30.37 ? 2458 HOH A O 1 HETATM 9025 O O . HOH G 7 . ? 47.444 79.488 -18.425 1.00 24.98 ? 2459 HOH A O 1 HETATM 9026 O O . HOH G 7 . ? 50.491 79.026 -15.814 1.00 25.90 ? 2460 HOH A O 1 HETATM 9027 O O . HOH G 7 . ? 52.503 78.864 -17.524 1.00 20.49 ? 2461 HOH A O 1 HETATM 9028 O O . HOH G 7 . ? 60.008 83.879 -16.766 1.00 34.16 ? 2462 HOH A O 1 HETATM 9029 O O . HOH G 7 . ? 61.128 77.293 -13.000 1.00 19.54 ? 2463 HOH A O 1 HETATM 9030 O O . HOH G 7 . ? 61.806 76.242 -10.662 1.00 16.78 ? 2464 HOH A O 1 HETATM 9031 O O . HOH G 7 . ? 59.537 76.389 -9.025 1.00 14.29 ? 2465 HOH A O 1 HETATM 9032 O O . HOH G 7 . ? 59.232 77.008 -4.339 1.00 28.16 ? 2466 HOH A O 1 HETATM 9033 O O . HOH G 7 . ? 57.270 75.383 -3.077 1.00 31.39 ? 2467 HOH A O 1 HETATM 9034 O O . HOH G 7 . ? 46.019 70.880 0.021 1.00 13.18 ? 2468 HOH A O 1 HETATM 9035 O O . HOH G 7 . ? 43.482 73.068 5.699 1.00 11.45 ? 2469 HOH A O 1 HETATM 9036 O O . HOH G 7 . ? 46.720 74.365 7.708 1.00 10.74 ? 2470 HOH A O 1 HETATM 9037 O O . HOH G 7 . ? 46.063 79.486 4.869 1.00 23.10 ? 2471 HOH A O 1 HETATM 9038 O O . HOH G 7 . ? 43.439 80.596 5.150 1.00 21.05 ? 2472 HOH A O 1 HETATM 9039 O O . HOH G 7 . ? 36.177 80.897 6.318 1.00 16.02 ? 2473 HOH A O 1 HETATM 9040 O O . HOH G 7 . ? 32.127 80.403 7.423 1.00 26.56 ? 2474 HOH A O 1 HETATM 9041 O O . HOH G 7 . ? 30.259 82.336 7.311 1.00 36.04 ? 2475 HOH A O 1 HETATM 9042 O O . HOH G 7 . ? 29.854 75.574 10.781 1.00 23.52 ? 2476 HOH A O 1 HETATM 9043 O O . HOH G 7 . ? 26.598 74.772 11.043 1.00 24.67 ? 2477 HOH A O 1 HETATM 9044 O O . HOH G 7 . ? 27.650 73.123 13.085 1.00 39.54 ? 2478 HOH A O 1 HETATM 9045 O O . HOH G 7 . ? 28.349 71.958 15.222 1.00 39.93 ? 2479 HOH A O 1 HETATM 9046 O O . HOH G 7 . ? 30.159 72.467 12.224 1.00 26.77 ? 2480 HOH A O 1 HETATM 9047 O O . HOH G 7 . ? 31.967 71.298 13.552 1.00 24.58 ? 2481 HOH A O 1 HETATM 9048 O O . HOH G 7 . ? 34.635 70.324 13.060 1.00 11.98 ? 2482 HOH A O 1 HETATM 9049 O O . HOH G 7 . ? 35.047 71.215 15.523 1.00 25.04 ? 2483 HOH A O 1 HETATM 9050 O O . HOH G 7 . ? 36.766 70.346 16.625 1.00 35.86 ? 2484 HOH A O 1 HETATM 9051 O O . HOH G 7 . ? 36.085 70.299 19.242 1.00 39.50 ? 2485 HOH A O 1 HETATM 9052 O O . HOH G 7 . ? 34.164 68.904 19.588 1.00 40.29 ? 2486 HOH A O 1 HETATM 9053 O O . HOH G 7 . ? 32.648 70.415 17.890 1.00 34.01 ? 2487 HOH A O 1 HETATM 9054 O O . HOH G 7 . ? 33.720 68.464 16.863 1.00 39.65 ? 2488 HOH A O 1 HETATM 9055 O O . HOH G 7 . ? 31.853 65.288 18.622 1.00 13.13 ? 2489 HOH A O 1 HETATM 9056 O O . HOH G 7 . ? 29.717 65.849 16.905 1.00 27.39 ? 2490 HOH A O 1 HETATM 9057 O O . HOH G 7 . ? 28.206 67.623 16.029 1.00 36.90 ? 2491 HOH A O 1 HETATM 9058 O O . HOH G 7 . ? 25.771 66.062 17.474 1.00 26.76 ? 2492 HOH A O 1 HETATM 9059 O O . HOH G 7 . ? 23.512 66.140 18.666 1.00 35.19 ? 2493 HOH A O 1 HETATM 9060 O O . HOH G 7 . ? 23.083 63.733 18.110 1.00 38.01 ? 2494 HOH A O 1 HETATM 9061 O O . HOH G 7 . ? 22.790 62.447 16.200 1.00 26.78 ? 2495 HOH A O 1 HETATM 9062 O O . HOH G 7 . ? 21.192 63.507 14.662 1.00 31.94 ? 2496 HOH A O 1 HETATM 9063 O O . HOH G 7 . ? 24.416 63.105 11.405 1.00 37.11 ? 2497 HOH A O 1 HETATM 9064 O O . HOH G 7 . ? 26.390 62.777 12.792 1.00 28.11 ? 2498 HOH A O 1 HETATM 9065 O O . HOH G 7 . ? 26.956 63.755 9.847 1.00 19.47 ? 2499 HOH A O 1 HETATM 9066 O O . HOH G 7 . ? 25.622 65.417 8.405 1.00 19.32 ? 2500 HOH A O 1 HETATM 9067 O O . HOH G 7 . ? 24.176 63.308 7.465 1.00 10.76 ? 2501 HOH A O 1 HETATM 9068 O O . HOH G 7 . ? 24.676 61.233 9.193 1.00 14.78 ? 2502 HOH A O 1 HETATM 9069 O O . HOH G 7 . ? 27.082 59.263 8.471 1.00 17.63 ? 2503 HOH A O 1 HETATM 9070 O O . HOH G 7 . ? 23.813 57.989 6.320 1.00 10.69 ? 2504 HOH A O 1 HETATM 9071 O O . HOH G 7 . ? 21.654 56.969 5.037 1.00 10.17 ? 2505 HOH A O 1 HETATM 9072 O O . HOH G 7 . ? 20.046 55.867 7.160 1.00 10.96 ? 2506 HOH A O 1 HETATM 9073 O O . HOH G 7 . ? 19.273 53.402 8.206 1.00 10.79 ? 2507 HOH A O 1 HETATM 9074 O O . HOH G 7 . ? 17.568 52.655 6.374 1.00 10.62 ? 2508 HOH A O 1 HETATM 9075 O O . HOH G 7 . ? 17.051 56.144 10.315 1.00 11.23 ? 2509 HOH A O 1 HETATM 9076 O O . HOH G 7 . ? 19.309 55.086 11.511 1.00 11.22 ? 2510 HOH A O 1 HETATM 9077 O O . HOH G 7 . ? 18.365 54.832 14.177 1.00 11.35 ? 2511 HOH A O 1 HETATM 9078 O O . HOH G 7 . ? 20.109 54.655 16.232 1.00 11.43 ? 2512 HOH A O 1 HETATM 9079 O O . HOH G 7 . ? 16.741 56.938 12.982 1.00 12.61 ? 2513 HOH A O 1 HETATM 9080 O O . HOH G 7 . ? 15.529 60.235 15.502 1.00 13.62 ? 2514 HOH A O 1 HETATM 9081 O O . HOH G 7 . ? 13.810 62.224 14.707 1.00 23.92 ? 2515 HOH A O 1 HETATM 9082 O O . HOH G 7 . ? 13.233 62.737 11.887 1.00 26.89 ? 2516 HOH A O 1 HETATM 9083 O O . HOH G 7 . ? 13.979 58.136 16.395 1.00 14.60 ? 2517 HOH A O 1 HETATM 9084 O O . HOH G 7 . ? 13.942 57.586 19.051 1.00 18.51 ? 2518 HOH A O 1 HETATM 9085 O O . HOH G 7 . ? 11.657 58.509 19.996 1.00 30.13 ? 2519 HOH A O 1 HETATM 9086 O O . HOH G 7 . ? 10.860 57.141 21.734 1.00 40.19 ? 2520 HOH A O 1 HETATM 9087 O O . HOH G 7 . ? 12.342 55.197 22.541 1.00 25.11 ? 2521 HOH A O 1 HETATM 9088 O O . HOH G 7 . ? 12.808 54.982 25.292 1.00 29.84 ? 2522 HOH A O 1 HETATM 9089 O O . HOH G 7 . ? 13.322 52.412 25.942 1.00 36.17 ? 2523 HOH A O 1 HETATM 9090 O O . HOH G 7 . ? 14.153 50.402 24.286 1.00 19.60 ? 2524 HOH A O 1 HETATM 9091 O O . HOH G 7 . ? 13.498 51.467 21.821 1.00 17.80 ? 2525 HOH A O 1 HETATM 9092 O O . HOH G 7 . ? 10.827 51.315 21.446 1.00 24.20 ? 2526 HOH A O 1 HETATM 9093 O O . HOH G 7 . ? 10.292 50.604 18.953 1.00 21.50 ? 2527 HOH A O 1 HETATM 9094 O O . HOH G 7 . ? 9.421 52.272 16.952 1.00 19.03 ? 2528 HOH A O 1 HETATM 9095 O O . HOH G 7 . ? 7.552 54.514 17.380 1.00 33.18 ? 2529 HOH A O 1 HETATM 9096 O O . HOH G 7 . ? 8.739 56.921 16.211 1.00 48.17 ? 2530 HOH A O 1 HETATM 9097 O O . HOH G 7 . ? 11.792 51.406 14.410 1.00 14.27 ? 2531 HOH A O 1 HETATM 9098 O O . HOH G 7 . ? 14.018 48.983 15.417 1.00 14.40 ? 2532 HOH A O 1 HETATM 9099 O O . HOH G 7 . ? 12.587 49.401 17.871 1.00 19.13 ? 2533 HOH A O 1 HETATM 9100 O O . HOH G 7 . ? 14.392 49.653 19.957 1.00 16.17 ? 2534 HOH A O 1 HETATM 9101 O O . HOH G 7 . ? 11.493 46.773 17.954 1.00 20.13 ? 2535 HOH A O 1 HETATM 9102 O O . HOH G 7 . ? 6.249 46.496 16.306 1.00 36.78 ? 2536 HOH A O 1 HETATM 9103 O O . HOH G 7 . ? 12.061 41.391 20.067 1.00 30.64 ? 2537 HOH A O 1 HETATM 9104 O O . HOH G 7 . ? 12.993 43.970 22.869 1.00 37.66 ? 2538 HOH A O 1 HETATM 9105 O O . HOH G 7 . ? 13.933 45.073 27.253 1.00 30.80 ? 2539 HOH A O 1 HETATM 9106 O O . HOH G 7 . ? 14.505 47.357 27.037 1.00 40.79 ? 2540 HOH A O 1 HETATM 9107 O O . HOH G 7 . ? 16.543 49.000 24.145 1.00 15.27 ? 2541 HOH A O 1 HETATM 9108 O O . HOH G 7 . ? 18.260 43.093 27.479 1.00 31.09 ? 2542 HOH A O 1 HETATM 9109 O O . HOH G 7 . ? 18.054 41.834 25.442 1.00 28.18 ? 2543 HOH A O 1 HETATM 9110 O O . HOH G 7 . ? 19.182 39.826 26.649 1.00 31.42 ? 2544 HOH A O 1 HETATM 9111 O O . HOH G 7 . ? 19.943 35.673 25.750 1.00 29.71 ? 2545 HOH A O 1 HETATM 9112 O O . HOH G 7 . ? 22.682 31.366 29.773 1.00 29.56 ? 2546 HOH A O 1 HETATM 9113 O O . HOH G 7 . ? 20.902 31.715 31.638 1.00 35.16 ? 2547 HOH A O 1 HETATM 9114 O O . HOH G 7 . ? 21.695 29.273 28.305 1.00 34.06 ? 2548 HOH A O 1 HETATM 9115 O O . HOH G 7 . ? 26.236 32.807 28.967 1.00 25.09 ? 2549 HOH A O 1 HETATM 9116 O O . HOH G 7 . ? 27.367 35.057 29.583 1.00 22.82 ? 2550 HOH A O 1 HETATM 9117 O O . HOH G 7 . ? 26.310 37.475 29.542 1.00 18.21 ? 2551 HOH A O 1 HETATM 9118 O O . HOH G 7 . ? 30.284 36.653 29.125 1.00 22.67 ? 2552 HOH A O 1 HETATM 9119 O O . HOH G 7 . ? 28.524 35.033 32.406 1.00 36.11 ? 2553 HOH A O 1 HETATM 9120 O O . HOH G 7 . ? 24.812 34.685 36.000 1.00 35.58 ? 2554 HOH A O 1 HETATM 9121 O O . HOH G 7 . ? 22.200 35.170 35.073 1.00 34.01 ? 2555 HOH A O 1 HETATM 9122 O O . HOH G 7 . ? 21.234 41.751 35.300 1.00 27.01 ? 2556 HOH A O 1 HETATM 9123 O O . HOH G 7 . ? 19.855 43.306 33.925 1.00 23.60 ? 2557 HOH A O 1 HETATM 9124 O O . HOH G 7 . ? 17.301 41.900 32.260 1.00 35.50 ? 2558 HOH A O 1 HETATM 9125 O O . HOH G 7 . ? 14.702 47.067 32.372 1.00 26.88 ? 2559 HOH A O 1 HETATM 9126 O O . HOH G 7 . ? 12.382 47.656 31.449 1.00 30.52 ? 2560 HOH A O 1 HETATM 9127 O O . HOH G 7 . ? 17.795 52.829 35.927 1.00 33.29 ? 2561 HOH A O 1 HETATM 9128 O O . HOH G 7 . ? 17.817 50.734 38.421 1.00 41.90 ? 2562 HOH A O 1 HETATM 9129 O O . HOH G 7 . ? 19.025 48.625 37.820 1.00 19.94 ? 2563 HOH A O 1 HETATM 9130 O O . HOH G 7 . ? 21.218 47.518 39.136 1.00 20.81 ? 2564 HOH A O 1 HETATM 9131 O O . HOH G 7 . ? 28.195 49.545 38.514 1.00 25.90 ? 2565 HOH A O 1 HETATM 9132 O O . HOH G 7 . ? 29.189 47.124 37.173 1.00 22.79 ? 2566 HOH A O 1 HETATM 9133 O O . HOH G 7 . ? 31.726 47.507 38.014 1.00 46.15 ? 2567 HOH A O 1 HETATM 9134 O O . HOH G 7 . ? 34.171 48.181 36.487 1.00 38.10 ? 2568 HOH A O 1 HETATM 9135 O O . HOH G 7 . ? 34.815 51.300 36.028 1.00 33.70 ? 2569 HOH A O 1 HETATM 9136 O O . HOH G 7 . ? 39.692 49.772 36.172 1.00 30.09 ? 2570 HOH A O 1 HETATM 9137 O O . HOH G 7 . ? 40.091 52.705 36.267 1.00 28.23 ? 2571 HOH A O 1 HETATM 9138 O O . HOH G 7 . ? 42.669 53.415 35.552 1.00 21.72 ? 2572 HOH A O 1 HETATM 9139 O O . HOH G 7 . ? 44.643 55.341 36.088 1.00 38.83 ? 2573 HOH A O 1 HETATM 9140 O O . HOH G 7 . ? 43.568 56.765 33.474 1.00 35.03 ? 2574 HOH A O 1 HETATM 9141 O O . HOH G 7 . ? 41.908 58.270 34.625 1.00 28.96 ? 2575 HOH A O 1 HETATM 9142 O O . HOH G 7 . ? 42.000 61.843 33.808 1.00 37.01 ? 2576 HOH A O 1 HETATM 9143 O O . HOH G 7 . ? 37.775 62.428 35.362 1.00 30.89 ? 2577 HOH A O 1 HETATM 9144 O O . HOH G 7 . ? 35.223 62.482 33.959 1.00 25.09 ? 2578 HOH A O 1 HETATM 9145 O O . HOH G 7 . ? 34.001 59.868 34.995 1.00 40.08 ? 2579 HOH A O 1 HETATM 9146 O O . HOH G 7 . ? 30.111 59.445 34.998 1.00 36.44 ? 2580 HOH A O 1 HETATM 9147 O O . HOH G 7 . ? 31.485 57.596 37.372 1.00 26.40 ? 2581 HOH A O 1 HETATM 9148 O O . HOH G 7 . ? 28.950 55.309 39.982 1.00 29.83 ? 2582 HOH A O 1 HETATM 9149 O O . HOH G 7 . ? 26.665 57.657 40.331 1.00 40.00 ? 2583 HOH A O 1 HETATM 9150 O O . HOH G 7 . ? 24.332 57.389 38.782 1.00 29.88 ? 2584 HOH A O 1 HETATM 9151 O O . HOH G 7 . ? 21.243 58.314 37.818 1.00 50.65 ? 2585 HOH A O 1 HETATM 9152 O O . HOH G 7 . ? 21.629 55.668 40.218 1.00 23.51 ? 2586 HOH A O 1 HETATM 9153 O O . HOH G 7 . ? 21.003 54.305 47.206 1.00 37.22 ? 2587 HOH A O 1 HETATM 9154 O O . HOH G 7 . ? 21.207 51.831 47.736 1.00 25.68 ? 2588 HOH A O 1 HETATM 9155 O O . HOH G 7 . ? 28.197 47.755 46.174 1.00 42.74 ? 2589 HOH A O 1 HETATM 9156 O O . HOH G 7 . ? 27.771 52.163 42.483 1.00 34.45 ? 2590 HOH A O 1 HETATM 9157 O O . HOH G 7 . ? 30.501 51.769 39.668 1.00 44.09 ? 2591 HOH A O 1 HETATM 9158 O O . HOH G 7 . ? 28.262 44.553 38.292 1.00 27.43 ? 2592 HOH A O 1 HETATM 9159 O O . HOH G 7 . ? 31.110 44.043 40.902 1.00 35.92 ? 2593 HOH A O 1 HETATM 9160 O O . HOH G 7 . ? 34.873 45.955 33.341 1.00 17.18 ? 2594 HOH A O 1 HETATM 9161 O O . HOH G 7 . ? 36.064 45.272 30.917 1.00 16.02 ? 2595 HOH A O 1 HETATM 9162 O O . HOH G 7 . ? 37.545 47.263 29.727 1.00 17.75 ? 2596 HOH A O 1 HETATM 9163 O O . HOH G 7 . ? 39.377 49.310 30.111 1.00 18.68 ? 2597 HOH A O 1 HETATM 9164 O O . HOH G 7 . ? 42.084 48.732 31.277 1.00 20.02 ? 2598 HOH A O 1 HETATM 9165 O O . HOH G 7 . ? 41.209 50.462 33.159 1.00 18.37 ? 2599 HOH A O 1 HETATM 9166 O O . HOH G 7 . ? 40.640 57.217 30.996 1.00 22.13 ? 2600 HOH A O 1 HETATM 9167 O O . HOH G 7 . ? 45.905 58.226 32.943 1.00 38.84 ? 2601 HOH A O 1 HETATM 9168 O O . HOH G 7 . ? 46.919 63.445 29.741 1.00 41.54 ? 2602 HOH A O 1 HETATM 9169 O O . HOH G 7 . ? 47.910 66.045 26.870 1.00 26.60 ? 2603 HOH A O 1 HETATM 9170 O O . HOH G 7 . ? 46.400 68.523 26.460 1.00 29.97 ? 2604 HOH A O 1 HETATM 9171 O O . HOH G 7 . ? 42.048 67.494 29.292 1.00 23.81 ? 2605 HOH A O 1 HETATM 9172 O O . HOH G 7 . ? 39.816 67.094 31.343 1.00 21.69 ? 2606 HOH A O 1 HETATM 9173 O O . HOH G 7 . ? 36.709 66.849 25.568 1.00 20.99 ? 2607 HOH A O 1 HETATM 9174 O O . HOH G 7 . ? 35.734 68.480 23.175 1.00 26.85 ? 2608 HOH A O 1 HETATM 9175 O O . HOH G 7 . ? 35.831 65.603 22.205 1.00 20.87 ? 2609 HOH A O 1 HETATM 9176 O O . HOH G 7 . ? 37.097 68.194 20.338 1.00 21.75 ? 2610 HOH A O 1 HETATM 9177 O O . HOH G 7 . ? 37.081 72.300 20.163 1.00 36.91 ? 2611 HOH A O 1 HETATM 9178 O O . HOH G 7 . ? 35.452 71.590 22.050 1.00 42.28 ? 2612 HOH A O 1 HETATM 9179 O O . HOH G 7 . ? 33.026 73.024 21.194 1.00 33.44 ? 2613 HOH A O 1 HETATM 9180 O O . HOH G 7 . ? 31.935 75.487 21.147 1.00 33.19 ? 2614 HOH A O 1 HETATM 9181 O O . HOH G 7 . ? 29.461 75.208 22.245 1.00 19.58 ? 2615 HOH A O 1 HETATM 9182 O O . HOH G 7 . ? 28.709 72.570 22.516 1.00 17.68 ? 2616 HOH A O 1 HETATM 9183 O O . HOH G 7 . ? 27.370 71.839 20.442 1.00 39.08 ? 2617 HOH A O 1 HETATM 9184 O O . HOH G 7 . ? 28.035 69.681 18.907 1.00 37.84 ? 2618 HOH A O 1 HETATM 9185 O O . HOH G 7 . ? 30.675 69.510 19.865 1.00 23.22 ? 2619 HOH A O 1 HETATM 9186 O O . HOH G 7 . ? 30.972 71.103 21.811 1.00 25.55 ? 2620 HOH A O 1 HETATM 9187 O O . HOH G 7 . ? 32.497 69.555 24.333 1.00 20.06 ? 2621 HOH A O 1 HETATM 9188 O O . HOH G 7 . ? 31.707 67.058 20.873 1.00 23.55 ? 2622 HOH A O 1 HETATM 9189 O O . HOH G 7 . ? 28.762 65.316 19.686 1.00 17.65 ? 2623 HOH A O 1 HETATM 9190 O O . HOH G 7 . ? 26.500 66.983 19.864 1.00 31.57 ? 2624 HOH A O 1 HETATM 9191 O O . HOH G 7 . ? 24.709 68.384 21.811 1.00 20.53 ? 2625 HOH A O 1 HETATM 9192 O O . HOH G 7 . ? 22.437 68.194 20.416 1.00 25.07 ? 2626 HOH A O 1 HETATM 9193 O O . HOH G 7 . ? 20.422 68.247 22.150 1.00 23.53 ? 2627 HOH A O 1 HETATM 9194 O O . HOH G 7 . ? 17.469 67.329 25.548 1.00 43.22 ? 2628 HOH A O 1 HETATM 9195 O O . HOH G 7 . ? 17.976 66.190 27.884 1.00 26.93 ? 2629 HOH A O 1 HETATM 9196 O O . HOH G 7 . ? 16.427 66.056 29.519 1.00 32.35 ? 2630 HOH A O 1 HETATM 9197 O O . HOH G 7 . ? 20.670 65.242 27.354 1.00 21.12 ? 2631 HOH A O 1 HETATM 9198 O O . HOH G 7 . ? 22.574 65.953 29.239 1.00 26.71 ? 2632 HOH A O 1 HETATM 9199 O O . HOH G 7 . ? 22.239 65.727 32.281 1.00 27.93 ? 2633 HOH A O 1 HETATM 9200 O O . HOH G 7 . ? 22.268 62.883 33.590 1.00 30.81 ? 2634 HOH A O 1 HETATM 9201 O O . HOH G 7 . ? 24.331 60.955 36.122 1.00 33.68 ? 2635 HOH A O 1 HETATM 9202 O O . HOH G 7 . ? 23.178 56.028 30.828 1.00 16.69 ? 2636 HOH A O 1 HETATM 9203 O O . HOH G 7 . ? 18.400 59.605 31.738 1.00 33.79 ? 2637 HOH A O 1 HETATM 9204 O O . HOH G 7 . ? 14.653 55.751 27.361 1.00 26.48 ? 2638 HOH A O 1 HETATM 9205 O O . HOH G 7 . ? 18.139 60.602 24.407 1.00 17.03 ? 2639 HOH A O 1 HETATM 9206 O O . HOH G 7 . ? 11.787 62.156 23.001 1.00 35.95 ? 2640 HOH A O 1 HETATM 9207 O O . HOH G 7 . ? 11.250 69.548 26.507 1.00 29.42 ? 2641 HOH A O 1 HETATM 9208 O O . HOH G 7 . ? 14.060 69.562 26.759 1.00 21.18 ? 2642 HOH A O 1 HETATM 9209 O O . HOH G 7 . ? 24.844 71.354 22.814 1.00 35.01 ? 2643 HOH A O 1 HETATM 9210 O O . HOH G 7 . ? 27.728 67.724 28.228 1.00 19.73 ? 2644 HOH A O 1 HETATM 9211 O O . HOH G 7 . ? 28.054 65.402 30.858 1.00 48.65 ? 2645 HOH A O 1 HETATM 9212 O O . HOH G 7 . ? 28.329 66.820 33.232 1.00 36.44 ? 2646 HOH A O 1 HETATM 9213 O O . HOH G 7 . ? 27.163 72.358 34.061 1.00 30.77 ? 2647 HOH A O 1 HETATM 9214 O O . HOH G 7 . ? 29.722 72.481 34.383 1.00 22.75 ? 2648 HOH A O 1 HETATM 9215 O O . HOH G 7 . ? 29.578 73.808 36.635 1.00 35.24 ? 2649 HOH A O 1 HETATM 9216 O O . HOH G 7 . ? 35.188 75.913 20.299 1.00 42.21 ? 2650 HOH A O 1 HETATM 9217 O O . HOH G 7 . ? 35.808 74.071 18.405 1.00 41.34 ? 2651 HOH A O 1 HETATM 9218 O O . HOH G 7 . ? 36.191 73.676 15.683 1.00 29.08 ? 2652 HOH A O 1 HETATM 9219 O O . HOH G 7 . ? 35.563 76.291 14.935 1.00 31.95 ? 2653 HOH A O 1 HETATM 9220 O O . HOH G 7 . ? 34.813 77.485 12.338 1.00 21.49 ? 2654 HOH A O 1 HETATM 9221 O O . HOH G 7 . ? 35.201 80.173 12.726 1.00 34.86 ? 2655 HOH A O 1 HETATM 9222 O O . HOH G 7 . ? 33.546 80.975 15.094 1.00 38.72 ? 2656 HOH A O 1 HETATM 9223 O O . HOH G 7 . ? 39.275 80.202 12.205 1.00 36.94 ? 2657 HOH A O 1 HETATM 9224 O O . HOH G 7 . ? 38.572 76.904 17.928 1.00 33.99 ? 2658 HOH A O 1 HETATM 9225 O O . HOH G 7 . ? 33.075 73.180 18.071 1.00 37.20 ? 2659 HOH A O 1 HETATM 9226 O O . HOH G 7 . ? 34.319 67.669 12.422 1.00 9.57 ? 2660 HOH A O 1 HETATM 9227 O O . HOH G 7 . ? 38.682 62.276 8.409 1.00 9.91 ? 2661 HOH A O 1 HETATM 9228 O O . HOH G 7 . ? 40.151 62.698 5.978 1.00 8.51 ? 2662 HOH A O 1 HETATM 9229 O O . HOH G 7 . ? 40.087 56.194 5.731 1.00 11.76 ? 2663 HOH A O 1 HETATM 9230 O O . HOH G 7 . ? 39.664 55.597 2.986 1.00 12.89 ? 2664 HOH A O 1 HETATM 9231 O O . HOH G 7 . ? 37.532 56.911 1.666 1.00 8.63 ? 2665 HOH A O 1 HETATM 9232 O O . HOH G 7 . ? 38.812 52.928 2.149 1.00 24.73 ? 2666 HOH A O 1 HETATM 9233 O O . HOH G 7 . ? 35.913 52.957 1.319 1.00 9.67 ? 2667 HOH A O 1 HETATM 9234 O O . HOH G 7 . ? 34.216 52.313 -0.974 1.00 8.15 ? 2668 HOH A O 1 HETATM 9235 O O . HOH G 7 . ? 36.710 51.495 3.797 1.00 11.43 ? 2669 HOH A O 1 HETATM 9236 O O . HOH G 7 . ? 41.930 55.068 1.353 1.00 22.38 ? 2670 HOH A O 1 HETATM 9237 O O . HOH G 7 . ? 42.746 56.473 2.876 1.00 17.47 ? 2671 HOH A O 1 HETATM 9238 O O . HOH G 7 . ? 42.930 56.709 6.173 1.00 10.39 ? 2672 HOH A O 1 HETATM 9239 O O . HOH G 7 . ? 37.761 58.976 11.025 1.00 8.68 ? 2673 HOH A O 1 HETATM 9240 O O . HOH G 7 . ? 36.904 57.633 13.315 1.00 8.35 ? 2674 HOH A O 1 HETATM 9241 O O . HOH G 7 . ? 39.344 57.291 14.766 1.00 8.76 ? 2675 HOH A O 1 HETATM 9242 O O . HOH G 7 . ? 41.250 58.929 13.500 1.00 9.13 ? 2676 HOH A O 1 HETATM 9243 O O . HOH G 7 . ? 43.018 48.032 11.251 1.00 11.49 ? 2677 HOH A O 1 HETATM 9244 O O . HOH G 7 . ? 44.410 45.968 10.060 1.00 13.13 ? 2678 HOH A O 1 HETATM 9245 O O . HOH G 7 . ? 41.639 43.165 7.940 1.00 16.54 ? 2679 HOH A O 1 HETATM 9246 O O . HOH G 7 . ? 44.857 40.263 13.296 1.00 33.69 ? 2680 HOH A O 1 HETATM 9247 O O . HOH G 7 . ? 41.882 39.187 16.652 1.00 26.93 ? 2681 HOH A O 1 HETATM 9248 O O . HOH G 7 . ? 39.241 38.895 17.302 1.00 16.79 ? 2682 HOH A O 1 HETATM 9249 O O . HOH G 7 . ? 39.744 39.671 20.090 1.00 26.95 ? 2683 HOH A O 1 HETATM 9250 O O . HOH G 7 . ? 38.007 38.304 21.840 1.00 37.57 ? 2684 HOH A O 1 HETATM 9251 O O . HOH G 7 . ? 37.229 37.653 25.182 1.00 41.63 ? 2685 HOH A O 1 HETATM 9252 O O . HOH G 7 . ? 37.646 40.432 26.587 1.00 31.57 ? 2686 HOH A O 1 HETATM 9253 O O . HOH G 7 . ? 39.579 41.452 25.598 1.00 37.80 ? 2687 HOH A O 1 HETATM 9254 O O . HOH G 7 . ? 39.249 43.585 26.838 1.00 30.61 ? 2688 HOH A O 1 HETATM 9255 O O . HOH G 7 . ? 39.956 45.266 25.458 1.00 28.61 ? 2689 HOH A O 1 HETATM 9256 O O . HOH G 7 . ? 37.168 45.625 27.454 1.00 13.41 ? 2690 HOH A O 1 HETATM 9257 O O . HOH G 7 . ? 35.253 43.746 28.725 1.00 13.53 ? 2691 HOH A O 1 HETATM 9258 O O . HOH G 7 . ? 39.081 42.990 22.727 1.00 25.85 ? 2692 HOH A O 1 HETATM 9259 O O . HOH G 7 . ? 34.270 34.337 16.269 1.00 19.16 ? 2693 HOH A O 1 HETATM 9260 O O . HOH G 7 . ? 31.873 33.565 17.236 1.00 31.58 ? 2694 HOH A O 1 HETATM 9261 O O . HOH G 7 . ? 30.570 33.950 21.067 1.00 42.30 ? 2695 HOH A O 1 HETATM 9262 O O . HOH G 7 . ? 29.478 31.547 21.972 1.00 31.42 ? 2696 HOH A O 1 HETATM 9263 O O . HOH G 7 . ? 24.283 34.294 15.674 1.00 29.25 ? 2697 HOH A O 1 HETATM 9264 O O . HOH G 7 . ? 25.283 33.236 13.396 1.00 30.67 ? 2698 HOH A O 1 HETATM 9265 O O . HOH G 7 . ? 24.369 33.072 9.647 1.00 27.84 ? 2699 HOH A O 1 HETATM 9266 O O . HOH G 7 . ? 24.734 32.862 6.559 1.00 23.44 ? 2700 HOH A O 1 HETATM 9267 O O . HOH G 7 . ? 30.624 29.570 5.988 1.00 41.77 ? 2701 HOH A O 1 HETATM 9268 O O . HOH G 7 . ? 31.174 33.417 2.879 1.00 23.33 ? 2702 HOH A O 1 HETATM 9269 O O . HOH G 7 . ? 25.886 39.654 5.279 1.00 10.21 ? 2703 HOH A O 1 HETATM 9270 O O . HOH G 7 . ? 26.292 39.985 8.023 1.00 10.71 ? 2704 HOH A O 1 HETATM 9271 O O . HOH G 7 . ? 24.030 41.849 6.975 1.00 11.06 ? 2705 HOH A O 1 HETATM 9272 O O . HOH G 7 . ? 28.174 39.565 11.328 1.00 12.58 ? 2706 HOH A O 1 HETATM 9273 O O . HOH G 7 . ? 27.256 41.271 13.344 1.00 13.04 ? 2707 HOH A O 1 HETATM 9274 O O . HOH G 7 . ? 28.287 43.789 13.219 1.00 9.20 ? 2708 HOH A O 1 HETATM 9275 O O . HOH G 7 . ? 27.196 46.298 13.699 1.00 13.04 ? 2709 HOH A O 1 HETATM 9276 O O . HOH G 7 . ? 27.887 48.454 12.095 1.00 13.76 ? 2710 HOH A O 1 HETATM 9277 O O . HOH G 7 . ? 27.565 50.848 13.236 1.00 17.59 ? 2711 HOH A O 1 HETATM 9278 O O . HOH G 7 . ? 25.651 52.133 12.953 1.00 21.14 ? 2712 HOH A O 1 HETATM 9279 O O . HOH G 7 . ? 25.446 53.574 11.141 1.00 12.55 ? 2713 HOH A O 1 HETATM 9280 O O . HOH G 7 . ? 30.206 55.720 17.166 1.00 9.38 ? 2714 HOH A O 1 HETATM 9281 O O . HOH G 7 . ? 27.742 53.349 20.059 1.00 13.17 ? 2715 HOH A O 1 HETATM 9282 O O . HOH G 7 . ? 27.035 52.379 22.514 1.00 23.46 ? 2716 HOH A O 1 HETATM 9283 O O . HOH G 7 . ? 27.542 50.045 23.273 1.00 22.49 ? 2717 HOH A O 1 HETATM 9284 O O . HOH G 7 . ? 27.999 61.004 19.388 1.00 10.08 ? 2718 HOH A O 1 HETATM 9285 O O . HOH G 7 . ? 26.454 63.651 16.686 1.00 18.98 ? 2719 HOH A O 1 HETATM 9286 O O . HOH G 7 . ? 24.071 67.466 9.753 1.00 24.29 ? 2720 HOH A O 1 HETATM 9287 O O . HOH G 7 . ? 20.825 67.904 8.570 1.00 17.13 ? 2721 HOH A O 1 HETATM 9288 O O . HOH G 7 . ? 20.882 65.175 7.737 1.00 14.27 ? 2722 HOH A O 1 HETATM 9289 O O . HOH G 7 . ? 27.991 66.267 7.252 1.00 12.27 ? 2723 HOH A O 1 HETATM 9290 O O . HOH G 7 . ? 26.256 72.500 5.578 1.00 11.38 ? 2724 HOH A O 1 HETATM 9291 O O . HOH G 7 . ? 25.198 73.436 8.928 1.00 20.97 ? 2725 HOH A O 1 HETATM 9292 O O . HOH G 7 . ? 23.043 72.412 10.829 1.00 36.93 ? 2726 HOH A O 1 HETATM 9293 O O . HOH G 7 . ? 22.105 76.363 8.750 1.00 25.78 ? 2727 HOH A O 1 HETATM 9294 O O . HOH G 7 . ? 26.292 75.709 1.607 1.00 17.23 ? 2728 HOH A O 1 HETATM 9295 O O . HOH G 7 . ? 21.486 78.328 -1.414 1.00 16.61 ? 2729 HOH A O 1 HETATM 9296 O O . HOH G 7 . ? 16.361 80.257 -1.336 1.00 38.15 ? 2730 HOH A O 1 HETATM 9297 O O . HOH G 7 . ? 10.593 76.874 -4.682 1.00 30.95 ? 2731 HOH A O 1 HETATM 9298 O O . HOH G 7 . ? 7.804 81.173 -4.208 1.00 31.71 ? 2732 HOH A O 1 HETATM 9299 O O . HOH G 7 . ? 12.258 74.925 -13.375 1.00 28.33 ? 2733 HOH A O 1 HETATM 9300 O O . HOH G 7 . ? 15.367 76.777 -13.618 1.00 28.95 ? 2734 HOH A O 1 HETATM 9301 O O . HOH G 7 . ? 15.863 75.032 -11.409 1.00 18.64 ? 2735 HOH A O 1 HETATM 9302 O O . HOH G 7 . ? 17.056 70.150 -16.217 1.00 12.49 ? 2736 HOH A O 1 HETATM 9303 O O . HOH G 7 . ? 16.040 71.942 -18.908 1.00 19.81 ? 2737 HOH A O 1 HETATM 9304 O O . HOH G 7 . ? 12.893 74.462 -18.989 1.00 34.09 ? 2738 HOH A O 1 HETATM 9305 O O . HOH G 7 . ? 16.439 67.713 -19.877 1.00 17.59 ? 2739 HOH A O 1 HETATM 9306 O O . HOH G 7 . ? 20.510 66.054 -19.586 1.00 12.03 ? 2740 HOH A O 1 HETATM 9307 O O . HOH G 7 . ? 20.254 58.639 -21.940 1.00 9.87 ? 2741 HOH A O 1 HETATM 9308 O O . HOH G 7 . ? 23.755 55.340 -23.386 1.00 9.72 ? 2742 HOH A O 1 HETATM 9309 O O . HOH G 7 . ? 28.595 49.567 -24.399 1.00 16.59 ? 2743 HOH A O 1 HETATM 9310 O O . HOH G 7 . ? 31.218 49.748 -23.993 1.00 12.05 ? 2744 HOH A O 1 HETATM 9311 O O . HOH G 7 . ? 27.471 48.251 -21.570 1.00 15.50 ? 2745 HOH A O 1 HETATM 9312 O O . HOH G 7 . ? 26.981 47.446 -23.930 1.00 28.83 ? 2746 HOH A O 1 HETATM 9313 O O . HOH G 7 . ? 25.070 46.762 -20.764 1.00 21.03 ? 2747 HOH A O 1 HETATM 9314 O O . HOH G 7 . ? 32.920 40.861 -17.823 1.00 23.02 ? 2748 HOH A O 1 HETATM 9315 O O . HOH G 7 . ? 33.544 38.790 -19.468 1.00 34.22 ? 2749 HOH A O 1 HETATM 9316 O O . HOH G 7 . ? 36.072 36.040 -18.333 1.00 35.22 ? 2750 HOH A O 1 HETATM 9317 O O . HOH G 7 . ? 36.815 34.970 -15.858 1.00 29.59 ? 2751 HOH A O 1 HETATM 9318 O O . HOH G 7 . ? 35.716 38.792 -16.055 1.00 27.21 ? 2752 HOH A O 1 HETATM 9319 O O . HOH G 7 . ? 36.342 35.232 -23.689 1.00 32.64 ? 2753 HOH A O 1 HETATM 9320 O O . HOH G 7 . ? 44.916 33.298 -19.202 1.00 43.55 ? 2754 HOH A O 1 HETATM 9321 O O . HOH G 7 . ? 40.992 52.199 -16.938 1.00 11.86 ? 2755 HOH A O 1 HETATM 9322 O O . HOH G 7 . ? 42.244 54.705 -17.415 1.00 21.45 ? 2756 HOH A O 1 HETATM 9323 O O . HOH G 7 . ? 42.979 59.296 -18.937 1.00 19.79 ? 2757 HOH A O 1 HETATM 9324 O O . HOH G 7 . ? 45.659 59.741 -18.303 1.00 10.98 ? 2758 HOH A O 1 HETATM 9325 O O . HOH G 7 . ? 39.156 62.736 -19.127 1.00 7.96 ? 2759 HOH A O 1 HETATM 9326 O O . HOH G 7 . ? 39.224 64.619 -14.823 1.00 10.32 ? 2760 HOH A O 1 HETATM 9327 O O . HOH G 7 . ? 41.997 63.372 -7.164 1.00 6.27 ? 2761 HOH A O 1 HETATM 9328 O O . HOH G 7 . ? 49.535 62.222 -8.676 1.00 8.75 ? 2762 HOH A O 1 HETATM 9329 O O . HOH G 7 . ? 50.821 59.787 -8.972 1.00 10.03 ? 2763 HOH A O 1 HETATM 9330 O O . HOH G 7 . ? 49.987 59.430 -11.564 1.00 8.91 ? 2764 HOH A O 1 HETATM 9331 O O . HOH G 7 . ? 53.587 59.748 -9.423 1.00 9.86 ? 2765 HOH A O 1 HETATM 9332 O O . HOH G 7 . ? 55.562 59.228 -11.518 1.00 8.85 ? 2766 HOH A O 1 HETATM 9333 O O . HOH G 7 . ? 49.743 57.548 -7.603 1.00 9.34 ? 2767 HOH A O 1 HETATM 9334 O O . HOH G 7 . ? 51.429 56.617 -5.593 1.00 9.10 ? 2768 HOH A O 1 HETATM 9335 O O . HOH G 7 . ? 52.144 54.011 -4.830 1.00 8.24 ? 2769 HOH A O 1 HETATM 9336 O O . HOH G 7 . ? 52.750 58.839 -1.760 1.00 11.92 ? 2770 HOH A O 1 HETATM 9337 O O . HOH G 7 . ? 67.049 55.289 0.859 1.00 21.70 ? 2771 HOH A O 1 HETATM 9338 O O . HOH G 7 . ? 71.297 59.579 1.039 1.00 33.21 ? 2772 HOH A O 1 HETATM 9339 O O . HOH G 7 . ? 73.380 62.984 -0.561 1.00 33.78 ? 2773 HOH A O 1 HETATM 9340 O O . HOH G 7 . ? 72.998 64.970 -7.707 1.00 21.99 ? 2774 HOH A O 1 HETATM 9341 O O . HOH G 7 . ? 72.999 66.479 -10.075 1.00 21.70 ? 2775 HOH A O 1 HETATM 9342 O O . HOH G 7 . ? 69.926 69.867 -12.645 1.00 12.84 ? 2776 HOH A O 1 HETATM 9343 O O . HOH G 7 . ? 76.296 71.118 -8.463 1.00 28.93 ? 2777 HOH A O 1 HETATM 9344 O O . HOH G 7 . ? 78.351 71.620 -10.105 1.00 28.54 ? 2778 HOH A O 1 HETATM 9345 O O . HOH G 7 . ? 73.560 74.050 -5.738 1.00 21.44 ? 2779 HOH A O 1 HETATM 9346 O O . HOH G 7 . ? 68.566 78.677 -18.179 1.00 17.36 ? 2780 HOH A O 1 HETATM 9347 O O . HOH G 7 . ? 70.284 83.833 -17.613 1.00 46.48 ? 2781 HOH A O 1 HETATM 9348 O O . HOH G 7 . ? 71.559 84.575 -20.060 1.00 27.15 ? 2782 HOH A O 1 HETATM 9349 O O . HOH G 7 . ? 73.278 82.237 -21.193 1.00 24.06 ? 2783 HOH A O 1 HETATM 9350 O O . HOH G 7 . ? 75.037 83.812 -23.173 1.00 33.44 ? 2784 HOH A O 1 HETATM 9351 O O . HOH G 7 . ? 74.099 86.597 -22.790 1.00 39.71 ? 2785 HOH A O 1 HETATM 9352 O O . HOH G 7 . ? 67.547 87.848 -23.455 1.00 18.77 ? 2786 HOH A O 1 HETATM 9353 O O . HOH G 7 . ? 64.851 87.532 -24.257 1.00 21.31 ? 2787 HOH A O 1 HETATM 9354 O O . HOH G 7 . ? 69.013 94.047 -25.669 1.00 27.27 ? 2788 HOH A O 1 HETATM 9355 O O . HOH G 7 . ? 72.299 95.498 -31.345 1.00 27.01 ? 2789 HOH A O 1 HETATM 9356 O O . HOH G 7 . ? 70.912 95.442 -34.977 1.00 35.60 ? 2790 HOH A O 1 HETATM 9357 O O . HOH G 7 . ? 68.074 97.768 -34.587 1.00 36.85 ? 2791 HOH A O 1 HETATM 9358 O O . HOH G 7 . ? 65.473 97.387 -35.853 1.00 33.71 ? 2792 HOH A O 1 HETATM 9359 O O . HOH G 7 . ? 67.826 88.057 -35.153 1.00 30.67 ? 2793 HOH A O 1 HETATM 9360 O O . HOH G 7 . ? 70.536 88.268 -35.476 1.00 36.25 ? 2794 HOH A O 1 HETATM 9361 O O . HOH G 7 . ? 67.371 85.422 -36.090 1.00 31.43 ? 2795 HOH A O 1 HETATM 9362 O O . HOH G 7 . ? 69.406 83.720 -36.069 1.00 25.91 ? 2796 HOH A O 1 HETATM 9363 O O . HOH G 7 . ? 69.846 81.736 -34.097 1.00 34.81 ? 2797 HOH A O 1 HETATM 9364 O O . HOH G 7 . ? 68.345 79.482 -34.936 1.00 22.75 ? 2798 HOH A O 1 HETATM 9365 O O . HOH G 7 . ? 69.223 76.912 -34.270 1.00 23.36 ? 2799 HOH A O 1 HETATM 9366 O O . HOH G 7 . ? 67.901 74.869 -35.179 1.00 25.02 ? 2800 HOH A O 1 HETATM 9367 O O . HOH G 7 . ? 71.479 76.383 -35.727 1.00 39.40 ? 2801 HOH A O 1 HETATM 9368 O O . HOH G 7 . ? 70.936 72.206 -34.446 1.00 37.76 ? 2802 HOH A O 1 HETATM 9369 O O . HOH G 7 . ? 67.707 77.033 -38.772 1.00 38.10 ? 2803 HOH A O 1 HETATM 9370 O O . HOH G 7 . ? 63.978 78.446 -37.982 1.00 28.21 ? 2804 HOH A O 1 HETATM 9371 O O . HOH G 7 . ? 64.276 77.748 -35.433 1.00 13.02 ? 2805 HOH A O 1 HETATM 9372 O O . HOH G 7 . ? 63.986 76.867 -40.476 1.00 31.05 ? 2806 HOH A O 1 HETATM 9373 O O . HOH G 7 . ? 61.372 76.459 -39.836 1.00 19.27 ? 2807 HOH A O 1 HETATM 9374 O O . HOH G 7 . ? 60.658 78.669 -41.750 1.00 25.65 ? 2808 HOH A O 1 HETATM 9375 O O . HOH G 7 . ? 62.035 81.252 -44.511 1.00 31.82 ? 2809 HOH A O 1 HETATM 9376 O O . HOH G 7 . ? 59.213 86.677 -45.993 1.00 38.02 ? 2810 HOH A O 1 HETATM 9377 O O . HOH G 7 . ? 54.194 82.585 -44.768 1.00 40.72 ? 2811 HOH A O 1 HETATM 9378 O O . HOH G 7 . ? 53.389 79.018 -44.744 1.00 37.14 ? 2812 HOH A O 1 HETATM 9379 O O . HOH G 7 . ? 53.408 76.726 -43.687 1.00 37.03 ? 2813 HOH A O 1 HETATM 9380 O O . HOH G 7 . ? 51.375 76.033 -41.083 1.00 28.81 ? 2814 HOH A O 1 HETATM 9381 O O . HOH G 7 . ? 47.516 78.785 -40.479 1.00 16.69 ? 2815 HOH A O 1 HETATM 9382 O O . HOH G 7 . ? 46.556 80.073 -42.658 1.00 21.09 ? 2816 HOH A O 1 HETATM 9383 O O . HOH G 7 . ? 43.810 79.719 -42.604 1.00 24.58 ? 2817 HOH A O 1 HETATM 9384 O O . HOH G 7 . ? 45.298 83.519 -43.262 1.00 34.63 ? 2818 HOH A O 1 HETATM 9385 O O . HOH G 7 . ? 47.083 83.065 -44.778 1.00 40.11 ? 2819 HOH A O 1 HETATM 9386 O O . HOH G 7 . ? 49.777 82.089 -43.927 1.00 17.80 ? 2820 HOH A O 1 HETATM 9387 O O . HOH G 7 . ? 51.016 80.050 -45.670 1.00 38.14 ? 2821 HOH A O 1 HETATM 9388 O O . HOH G 7 . ? 55.188 73.840 -43.122 1.00 37.26 ? 2822 HOH A O 1 HETATM 9389 O O . HOH G 7 . ? 59.797 70.085 -44.619 1.00 39.08 ? 2823 HOH A O 1 HETATM 9390 O O . HOH G 7 . ? 62.453 70.626 -45.101 1.00 39.39 ? 2824 HOH A O 1 HETATM 9391 O O . HOH G 7 . ? 61.557 69.056 -41.987 1.00 27.33 ? 2825 HOH A O 1 HETATM 9392 O O . HOH G 7 . ? 58.329 77.100 -38.587 1.00 13.46 ? 2826 HOH A O 1 HETATM 9393 O O . HOH G 7 . ? 61.799 82.907 -38.436 1.00 21.61 ? 2827 HOH A O 1 HETATM 9394 O O . HOH G 7 . ? 65.448 87.568 -41.263 1.00 38.02 ? 2828 HOH A O 1 HETATM 9395 O O . HOH G 7 . ? 48.242 89.024 -30.843 1.00 13.58 ? 2829 HOH A O 1 HETATM 9396 O O . HOH G 7 . ? 43.950 79.530 -21.584 1.00 39.58 ? 2830 HOH A O 1 HETATM 9397 O O . HOH G 7 . ? 42.144 75.137 -16.056 1.00 12.22 ? 2831 HOH A O 1 HETATM 9398 O O . HOH G 7 . ? 41.287 77.382 -14.180 1.00 13.15 ? 2832 HOH A O 1 HETATM 9399 O O . HOH G 7 . ? 40.349 82.660 -10.770 1.00 16.13 ? 2833 HOH A O 1 HETATM 9400 O O . HOH G 7 . ? 42.981 82.235 -9.980 1.00 24.18 ? 2834 HOH A O 1 HETATM 9401 O O . HOH G 7 . ? 40.818 85.112 -12.063 1.00 28.99 ? 2835 HOH A O 1 HETATM 9402 O O . HOH G 7 . ? 36.698 87.930 -11.750 1.00 38.18 ? 2836 HOH A O 1 HETATM 9403 O O . HOH G 7 . ? 34.187 87.010 -10.519 1.00 26.57 ? 2837 HOH A O 1 HETATM 9404 O O . HOH G 7 . ? 35.429 85.960 -8.221 1.00 25.93 ? 2838 HOH A O 1 HETATM 9405 O O . HOH G 7 . ? 32.152 85.037 -8.578 1.00 19.45 ? 2839 HOH A O 1 HETATM 9406 O O . HOH G 7 . ? 33.580 83.458 -10.420 1.00 13.34 ? 2840 HOH A O 1 HETATM 9407 O O . HOH G 7 . ? 32.724 80.952 -11.714 1.00 10.02 ? 2841 HOH A O 1 HETATM 9408 O O . HOH G 7 . ? 34.519 79.016 -9.161 1.00 10.44 ? 2842 HOH A O 1 HETATM 9409 O O . HOH G 7 . ? 35.808 77.437 -7.330 1.00 11.79 ? 2843 HOH A O 1 HETATM 9410 O O . HOH G 7 . ? 36.342 79.126 -5.057 1.00 19.31 ? 2844 HOH A O 1 HETATM 9411 O O . HOH G 7 . ? 33.336 78.529 -5.150 1.00 11.64 ? 2845 HOH A O 1 HETATM 9412 O O . HOH G 7 . ? 31.358 76.668 -6.313 1.00 9.98 ? 2846 HOH A O 1 HETATM 9413 O O . HOH G 7 . ? 37.079 71.755 -4.587 1.00 7.62 ? 2847 HOH A O 1 HETATM 9414 O O . HOH G 7 . ? 37.896 73.269 -2.313 1.00 9.83 ? 2848 HOH A O 1 HETATM 9415 O O . HOH G 7 . ? 36.632 72.564 0.221 1.00 8.16 ? 2849 HOH A O 1 HETATM 9416 O O . HOH G 7 . ? 33.071 62.613 0.042 1.00 6.99 ? 2850 HOH A O 1 HETATM 9417 O O . HOH G 7 . ? 32.550 59.965 -1.858 1.00 7.65 ? 2851 HOH A O 1 HETATM 9418 O O . HOH G 7 . ? 26.759 60.757 -3.328 1.00 8.72 ? 2852 HOH A O 1 HETATM 9419 O O . HOH G 7 . ? 24.341 55.528 -1.769 1.00 11.34 ? 2853 HOH A O 1 HETATM 9420 O O . HOH G 7 . ? 23.282 53.794 -3.635 1.00 12.96 ? 2854 HOH A O 1 HETATM 9421 O O . HOH G 7 . ? 24.094 53.019 -6.248 1.00 18.56 ? 2855 HOH A O 1 HETATM 9422 O O . HOH G 7 . ? 20.589 57.325 -5.230 1.00 9.96 ? 2856 HOH A O 1 HETATM 9423 O O . HOH G 7 . ? 21.510 57.823 -7.803 1.00 9.23 ? 2857 HOH A O 1 HETATM 9424 O O . HOH G 7 . ? 19.777 57.172 -11.751 1.00 13.00 ? 2858 HOH A O 1 HETATM 9425 O O . HOH G 7 . ? 14.296 54.190 -16.150 1.00 16.12 ? 2859 HOH A O 1 HETATM 9426 O O . HOH G 7 . ? 13.149 52.026 -15.061 1.00 28.28 ? 2860 HOH A O 1 HETATM 9427 O O . HOH G 7 . ? 12.876 51.470 -12.161 1.00 25.89 ? 2861 HOH A O 1 HETATM 9428 O O . HOH G 7 . ? 11.739 54.929 -12.324 1.00 17.38 ? 2862 HOH A O 1 HETATM 9429 O O . HOH G 7 . ? 9.560 53.397 -12.140 1.00 27.95 ? 2863 HOH A O 1 HETATM 9430 O O . HOH G 7 . ? 7.522 53.893 -10.211 1.00 22.13 ? 2864 HOH A O 1 HETATM 9431 O O . HOH G 7 . ? 7.902 57.722 -11.526 1.00 39.46 ? 2865 HOH A O 1 HETATM 9432 O O . HOH G 7 . ? 12.240 55.715 -15.114 1.00 16.93 ? 2866 HOH A O 1 HETATM 9433 O O . HOH G 7 . ? 10.492 57.687 -20.854 1.00 38.92 ? 2867 HOH A O 1 HETATM 9434 O O . HOH G 7 . ? 9.700 60.177 -20.322 1.00 24.88 ? 2868 HOH A O 1 HETATM 9435 O O . HOH G 7 . ? 4.268 56.494 -6.331 1.00 31.39 ? 2869 HOH A O 1 HETATM 9436 O O . HOH G 7 . ? 4.971 52.730 -6.095 1.00 33.88 ? 2870 HOH A O 1 HETATM 9437 O O . HOH G 7 . ? 15.878 44.790 -11.565 1.00 32.87 ? 2871 HOH A O 1 HETATM 9438 O O . HOH G 7 . ? 30.839 57.093 4.516 1.00 18.34 ? 2872 HOH A O 1 HETATM 9439 O O . HOH G 7 . ? 33.733 60.336 23.209 1.00 11.59 ? 2873 HOH A O 1 HETATM 9440 O O . HOH G 7 . ? 50.854 61.945 26.374 1.00 19.41 ? 2874 HOH A O 1 HETATM 9441 O O . HOH G 7 . ? 51.895 60.198 28.191 1.00 33.79 ? 2875 HOH A O 1 HETATM 9442 O O . HOH G 7 . ? 51.917 63.770 24.476 1.00 27.75 ? 2876 HOH A O 1 HETATM 9443 O O . HOH G 7 . ? 57.040 64.766 24.063 1.00 29.90 ? 2877 HOH A O 1 HETATM 9444 O O . HOH G 7 . ? 59.456 62.102 25.802 1.00 35.14 ? 2878 HOH A O 1 HETATM 9445 O O . HOH G 7 . ? 62.456 62.045 25.439 1.00 34.21 ? 2879 HOH A O 1 HETATM 9446 O O . HOH G 7 . ? 59.254 55.505 27.032 1.00 33.55 ? 2880 HOH A O 1 HETATM 9447 O O . HOH G 7 . ? 49.605 50.787 32.619 1.00 28.27 ? 2881 HOH A O 1 HETATM 9448 O O . HOH G 7 . ? 48.148 50.817 35.444 1.00 49.62 ? 2882 HOH A O 1 HETATM 9449 O O . HOH G 7 . ? 50.424 50.444 36.931 1.00 39.46 ? 2883 HOH A O 1 HETATM 9450 O O . HOH G 7 . ? 52.074 71.531 22.042 1.00 37.34 ? 2884 HOH A O 1 HETATM 9451 O O . HOH G 7 . ? 52.683 72.457 18.033 1.00 23.59 ? 2885 HOH A O 1 HETATM 9452 O O . HOH G 7 . ? 53.034 69.552 18.138 1.00 22.22 ? 2886 HOH A O 1 HETATM 9453 O O . HOH G 7 . ? 45.948 74.165 22.561 1.00 33.65 ? 2887 HOH A O 1 HETATM 9454 O O . HOH G 7 . ? 32.861 85.246 -5.604 1.00 17.44 ? 2888 HOH A O 1 HETATM 9455 O O . HOH G 7 . ? 31.473 87.573 -6.705 1.00 34.29 ? 2889 HOH A O 1 HETATM 9456 O O . HOH G 7 . ? 26.628 87.875 -3.884 1.00 35.45 ? 2890 HOH A O 1 HETATM 9457 O O . HOH G 7 . ? 24.064 83.004 -4.043 1.00 26.52 ? 2891 HOH A O 1 HETATM 9458 O O . HOH G 7 . ? 27.376 88.470 -12.469 1.00 26.39 ? 2892 HOH A O 1 HETATM 9459 O O . HOH G 7 . ? 27.918 102.163 -19.128 1.00 30.81 ? 2893 HOH A O 1 HETATM 9460 O O . HOH G 7 . ? 14.016 88.247 -19.818 1.00 34.66 ? 2894 HOH A O 1 HETATM 9461 O O . HOH G 7 . ? 28.974 93.544 -38.773 1.00 23.29 ? 2895 HOH A O 1 HETATM 9462 O O . HOH G 7 . ? 32.004 92.248 -36.896 1.00 23.91 ? 2896 HOH A O 1 HETATM 9463 O O . HOH G 7 . ? 38.757 93.776 -42.385 1.00 22.55 ? 2897 HOH A O 1 HETATM 9464 O O . HOH G 7 . ? 45.463 91.414 -44.399 1.00 35.97 ? 2898 HOH A O 1 HETATM 9465 O O . HOH G 7 . ? 46.096 96.824 -43.942 1.00 23.25 ? 2899 HOH A O 1 HETATM 9466 O O . HOH G 7 . ? 38.610 83.263 -39.736 1.00 21.14 ? 2900 HOH A O 1 HETATM 9467 O O . HOH G 7 . ? 36.796 82.238 -41.507 1.00 37.18 ? 2901 HOH A O 1 HETATM 9468 O O . HOH G 7 . ? 35.935 77.361 -43.068 1.00 32.96 ? 2902 HOH A O 1 HETATM 9469 O O . HOH G 7 . ? 37.569 75.385 -42.304 1.00 22.30 ? 2903 HOH A O 1 HETATM 9470 O O . HOH G 7 . ? 36.345 62.472 -38.565 1.00 29.03 ? 2904 HOH A O 1 HETATM 9471 O O . HOH G 7 . ? 36.119 63.387 -33.894 1.00 27.99 ? 2905 HOH A O 1 HETATM 9472 O O . HOH G 7 . ? 33.960 64.290 -32.305 1.00 13.53 ? 2906 HOH A O 1 HETATM 9473 O O . HOH G 7 . ? 37.514 61.300 -32.424 1.00 25.32 ? 2907 HOH A O 1 HETATM 9474 O O . HOH G 7 . ? 40.837 62.533 -31.856 1.00 20.98 ? 2908 HOH A O 1 HETATM 9475 O O . HOH G 7 . ? 43.358 63.479 -32.331 1.00 29.53 ? 2909 HOH A O 1 HETATM 9476 O O . HOH G 7 . ? 44.990 63.835 -34.506 1.00 51.92 ? 2910 HOH A O 1 HETATM 9477 O O . HOH G 7 . ? 44.860 66.227 -34.536 1.00 38.88 ? 2911 HOH A O 1 HETATM 9478 O O . HOH G 7 . ? 45.772 60.431 -31.081 1.00 51.82 ? 2912 HOH A O 1 HETATM 9479 O O . HOH G 7 . ? 42.729 59.190 -31.460 1.00 23.29 ? 2913 HOH A O 1 HETATM 9480 O O . HOH G 7 . ? 42.800 56.511 -31.529 1.00 22.88 ? 2914 HOH A O 1 HETATM 9481 O O . HOH G 7 . ? 40.779 55.706 -33.252 1.00 27.23 ? 2915 HOH A O 1 HETATM 9482 O O . HOH G 7 . ? 38.501 54.973 -31.648 1.00 15.02 ? 2916 HOH A O 1 HETATM 9483 O O . HOH G 7 . ? 37.210 52.606 -32.426 1.00 25.69 ? 2917 HOH A O 1 HETATM 9484 O O . HOH G 7 . ? 38.387 51.325 -29.859 1.00 19.52 ? 2918 HOH A O 1 HETATM 9485 O O . HOH G 7 . ? 39.482 48.476 -32.808 1.00 20.20 ? 2919 HOH A O 1 HETATM 9486 O O . HOH G 7 . ? 38.620 44.955 -33.644 1.00 20.81 ? 2920 HOH A O 1 HETATM 9487 O O . HOH G 7 . ? 49.492 48.834 -38.339 1.00 53.23 ? 2921 HOH A O 1 HETATM 9488 O O . HOH G 7 . ? 48.280 53.883 -31.332 1.00 41.44 ? 2922 HOH A O 1 HETATM 9489 O O . HOH G 7 . ? 50.030 58.281 -30.865 1.00 42.75 ? 2923 HOH A O 1 HETATM 9490 O O . HOH G 7 . ? 49.046 59.108 -28.649 1.00 26.99 ? 2924 HOH A O 1 HETATM 9491 O O . HOH G 7 . ? 48.259 61.588 -28.670 1.00 29.31 ? 2925 HOH A O 1 HETATM 9492 O O . HOH G 7 . ? 47.917 64.612 -27.963 1.00 35.32 ? 2926 HOH A O 1 HETATM 9493 O O . HOH G 7 . ? 49.861 64.828 -26.874 1.00 34.85 ? 2927 HOH A O 1 HETATM 9494 O O . HOH G 7 . ? 47.207 62.058 -25.698 1.00 19.93 ? 2928 HOH A O 1 HETATM 9495 O O . HOH G 7 . ? 47.779 59.224 -25.677 1.00 13.35 ? 2929 HOH A O 1 HETATM 9496 O O . HOH G 7 . ? 46.832 55.641 -25.515 1.00 17.26 ? 2930 HOH A O 1 HETATM 9497 O O . HOH G 7 . ? 43.740 54.833 -26.832 1.00 28.66 ? 2931 HOH A O 1 HETATM 9498 O O . HOH G 7 . ? 41.650 61.043 -29.670 1.00 16.12 ? 2932 HOH A O 1 HETATM 9499 O O . HOH G 7 . ? 43.588 62.580 -28.440 1.00 19.25 ? 2933 HOH A O 1 HETATM 9500 O O . HOH G 7 . ? 43.436 68.179 -25.329 1.00 12.60 ? 2934 HOH A O 1 HETATM 9501 O O . HOH G 7 . ? 50.384 61.205 -30.950 1.00 26.09 ? 2935 HOH A O 1 HETATM 9502 O O . HOH G 7 . ? 34.041 56.156 -26.300 1.00 10.55 ? 2936 HOH A O 1 HETATM 9503 O O . HOH G 7 . ? 32.040 58.392 -28.454 1.00 13.20 ? 2937 HOH A O 1 HETATM 9504 O O . HOH G 7 . ? 10.568 67.794 -2.012 1.00 27.34 ? 2938 HOH A O 1 HETATM 9505 O O . HOH G 7 . ? 13.206 68.534 1.008 1.00 17.88 ? 2939 HOH A O 1 HETATM 9506 O O . HOH G 7 . ? 11.594 67.011 2.587 1.00 56.27 ? 2940 HOH A O 1 HETATM 9507 O O . HOH G 7 . ? 12.683 70.926 -0.321 1.00 19.97 ? 2941 HOH A O 1 HETATM 9508 O O . HOH G 7 . ? 9.851 53.748 22.231 1.00 33.40 ? 2942 HOH A O 1 HETATM 9509 O O . HOH G 7 . ? 19.642 39.155 17.726 1.00 17.81 ? 2943 HOH A O 1 HETATM 9510 O O . HOH G 7 . ? 21.649 37.993 15.765 1.00 30.52 ? 2944 HOH A O 1 HETATM 9511 O O . HOH G 7 . ? 23.146 37.048 13.569 1.00 31.02 ? 2945 HOH A O 1 HETATM 9512 O O . HOH G 7 . ? 20.417 37.732 12.281 1.00 26.48 ? 2946 HOH A O 1 HETATM 9513 O O . HOH G 7 . ? 17.956 35.200 13.351 1.00 36.22 ? 2947 HOH A O 1 HETATM 9514 O O . HOH G 7 . ? 16.365 33.630 15.783 1.00 37.95 ? 2948 HOH A O 1 HETATM 9515 O O . HOH G 7 . ? 15.986 36.290 16.340 1.00 26.41 ? 2949 HOH A O 1 HETATM 9516 O O . HOH G 7 . ? 15.952 30.525 18.363 1.00 38.75 ? 2950 HOH A O 1 HETATM 9517 O O . HOH G 7 . ? 20.895 30.186 17.850 1.00 38.25 ? 2951 HOH A O 1 HETATM 9518 O O . HOH G 7 . ? 24.997 39.960 14.282 1.00 15.78 ? 2952 HOH A O 1 HETATM 9519 O O . HOH G 7 . ? 36.878 29.129 13.149 1.00 28.65 ? 2953 HOH A O 1 HETATM 9520 O O . HOH G 7 . ? 70.929 49.314 -0.163 1.00 24.55 ? 2954 HOH A O 1 HETATM 9521 O O . HOH G 7 . ? 74.141 51.995 1.640 1.00 33.25 ? 2955 HOH A O 1 HETATM 9522 O O . HOH G 7 . ? 79.567 51.263 -0.453 1.00 25.75 ? 2956 HOH A O 1 HETATM 9523 O O . HOH G 7 . ? 75.796 48.338 -5.656 1.00 33.74 ? 2957 HOH A O 1 HETATM 9524 O O . HOH G 7 . ? 73.664 46.193 -5.347 1.00 37.06 ? 2958 HOH A O 1 HETATM 9525 O O . HOH G 7 . ? 76.474 46.930 -11.680 1.00 26.77 ? 2959 HOH A O 1 HETATM 9526 O O . HOH G 7 . ? 73.024 43.577 -12.311 1.00 38.35 ? 2960 HOH A O 1 HETATM 9527 O O . HOH G 7 . ? 71.006 42.964 -15.565 1.00 29.74 ? 2961 HOH A O 1 HETATM 9528 O O . HOH G 7 . ? 69.163 41.627 -17.402 1.00 30.37 ? 2962 HOH A O 1 HETATM 9529 O O . HOH G 7 . ? 68.605 46.751 -16.546 1.00 25.51 ? 2963 HOH A O 1 HETATM 9530 O O . HOH G 7 . ? 72.028 47.091 -17.997 1.00 25.96 ? 2964 HOH A O 1 HETATM 9531 O O . HOH G 7 . ? 70.707 52.042 -12.544 1.00 19.99 ? 2965 HOH A O 1 HETATM 9532 O O . HOH G 7 . ? 71.139 54.286 -13.948 1.00 28.95 ? 2966 HOH A O 1 HETATM 9533 O O . HOH G 7 . ? 70.343 56.261 -12.472 1.00 33.30 ? 2967 HOH A O 1 HETATM 9534 O O . HOH G 7 . ? 72.182 58.645 -11.179 1.00 23.17 ? 2968 HOH A O 1 HETATM 9535 O O . HOH G 7 . ? 74.320 60.079 -9.507 1.00 35.78 ? 2969 HOH A O 1 HETATM 9536 O O . HOH G 7 . ? 68.739 58.174 -5.073 1.00 12.89 ? 2970 HOH A O 1 HETATM 9537 O O . HOH G 7 . ? 70.011 53.453 -10.342 1.00 29.97 ? 2971 HOH A O 1 HETATM 9538 O O . HOH G 7 . ? 73.842 53.873 -13.765 1.00 38.29 ? 2972 HOH A O 1 HETATM 9539 O O . HOH G 7 . ? 79.590 50.771 -11.439 1.00 40.32 ? 2973 HOH A O 1 HETATM 9540 O O . HOH G 7 . ? 79.348 50.575 -9.006 1.00 26.68 ? 2974 HOH A O 1 HETATM 9541 O O . HOH G 7 . ? 63.794 50.004 -14.022 1.00 11.94 ? 2975 HOH A O 1 HETATM 9542 O O . HOH G 7 . ? 66.526 62.515 -13.059 1.00 16.68 ? 2976 HOH A O 1 HETATM 9543 O O . HOH G 7 . ? 46.917 87.794 -13.434 1.00 41.06 ? 2977 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ARG 1 1 ? ? ? A . n A 1 2 SER 2 2 ? ? ? A . n A 1 3 SER 3 3 ? ? ? A . n A 1 4 HIS 4 4 ? ? ? A . n A 1 5 HIS 5 5 ? ? ? A . n A 1 6 HIS 6 6 ? ? ? A . n A 1 7 HIS 7 7 ? ? ? A . n A 1 8 HIS 8 8 ? ? ? A . n A 1 9 HIS 9 9 ? ? ? A . n A 1 10 GLY 10 10 ? ? ? A . n A 1 11 GLU 11 11 ? ? ? A . n A 1 12 PHE 12 12 ? ? ? A . n A 1 13 ASP 13 13 ? ? ? A . n A 1 14 ASP 14 14 ? ? ? A . n A 1 15 PRO 15 15 ? ? ? A . n A 1 16 ILE 16 16 ? ? ? A . n A 1 17 ARG 17 17 ? ? ? A . n A 1 18 PRO 18 18 ? ? ? A . n A 1 19 PRO 19 19 ? ? ? A . n A 1 20 LEU 20 20 ? ? ? A . n A 1 21 LYS 21 21 ? ? ? A . n A 1 22 VAL 22 22 ? ? ? A . n A 1 23 ALA 23 23 ? ? ? A . n A 1 24 ARG 24 24 ? ? ? A . n A 1 25 SER 25 25 ? ? ? A . n A 1 26 PRO 26 26 ? ? ? A . n A 1 27 ARG 27 27 ? ? ? A . n A 1 28 PRO 28 28 ? ? ? A . n A 1 29 GLY 29 29 ? ? ? A . n A 1 30 GLN 30 30 ? ? ? A . n A 1 31 CYS 31 31 31 CYS CYS A . n A 1 32 GLN 32 32 32 GLN GLN A . n A 1 33 ASP 33 33 33 ASP ASP A . n A 1 34 VAL 34 34 34 VAL VAL A . n A 1 35 VAL 35 35 35 VAL VAL A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 ASP 37 37 37 ASP ASP A . n A 1 38 VAL 38 38 38 VAL VAL A . n A 1 39 PRO 39 39 39 PRO PRO A . n A 1 40 ASN 40 40 40 ASN ASN A . n A 1 41 VAL 41 41 41 VAL VAL A . n A 1 42 ASP 42 42 42 ASP ASP A . n A 1 43 VAL 43 43 43 VAL VAL A . n A 1 44 GLN 44 44 44 GLN GLN A . n A 1 45 MET 45 45 45 MET MET A . n A 1 46 LEU 46 46 46 LEU LEU A . n A 1 47 GLU 47 47 47 GLU GLU A . n A 1 48 LEU 48 48 48 LEU LEU A . n A 1 49 TYR 49 49 49 TYR TYR A . n A 1 50 ASP 50 50 50 ASP ASP A . n A 1 51 ARG 51 51 51 ARG ARG A . n A 1 52 MET 52 52 52 MET MET A . n A 1 53 SER 53 53 53 SER SER A . n A 1 54 PHE 54 54 54 PHE PHE A . n A 1 55 LYS 55 55 55 LYS LYS A . n A 1 56 ASP 56 56 56 ASP ASP A . n A 1 57 ILE 57 57 57 ILE ILE A . n A 1 58 ASP 58 58 58 ASP ASP A . n A 1 59 GLY 59 59 59 GLY GLY A . n A 1 60 GLY 60 60 60 GLY GLY A . n A 1 61 VAL 61 61 61 VAL VAL A . n A 1 62 TRP 62 62 62 TRP TRP A . n A 1 63 LYS 63 63 63 LYS LYS A . n A 1 64 GLN 64 64 64 GLN GLN A . n A 1 65 GLY 65 65 65 GLY GLY A . n A 1 66 TRP 66 66 66 TRP TRP A . n A 1 67 ASN 67 67 67 ASN ASN A . n A 1 68 ILE 68 68 68 ILE ILE A . n A 1 69 LYS 69 69 69 LYS LYS A . n A 1 70 TYR 70 70 70 TYR TYR A . n A 1 71 ASP 71 71 71 ASP ASP A . n A 1 72 PRO 72 72 72 PRO PRO A . n A 1 73 LEU 73 73 73 LEU LEU A . n A 1 74 LYS 74 74 74 LYS LYS A . n A 1 75 TYR 75 75 75 TYR TYR A . n A 1 76 ASN 76 76 76 ASN ASN A . n A 1 77 ALA 77 77 77 ALA ALA A . n A 1 78 HIS 78 78 78 HIS HIS A . n A 1 79 HIS 79 79 79 HIS HIS A . n A 1 80 LYS 80 80 80 LYS LYS A . n A 1 81 LEU 81 81 81 LEU LEU A . n A 1 82 LYS 82 82 82 LYS LYS A . n A 1 83 VAL 83 83 83 VAL VAL A . n A 1 84 PHE 84 84 84 PHE PHE A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 VAL 86 86 86 VAL VAL A . n A 1 87 PRO 87 87 87 PRO PRO A . n A 1 88 HIS 88 88 88 HIS HIS A . n A 1 89 SER 89 89 89 SER SER A . n A 1 90 HIS 90 90 90 HIS HIS A . n A 1 91 ASN 91 91 91 ASN ASN A . n A 1 92 ASP 92 92 92 ASP ASP A . n A 1 93 PRO 93 93 93 PRO PRO A . n A 1 94 GLY 94 94 94 GLY GLY A . n A 1 95 TRP 95 95 95 TRP TRP A . n A 1 96 ILE 96 96 96 ILE ILE A . n A 1 97 GLN 97 97 97 GLN GLN A . n A 1 98 THR 98 98 98 THR THR A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 GLU 100 100 100 GLU GLU A . n A 1 101 GLU 101 101 101 GLU GLU A . n A 1 102 TYR 102 102 102 TYR TYR A . n A 1 103 TYR 103 103 103 TYR TYR A . n A 1 104 GLN 104 104 104 GLN GLN A . n A 1 105 HIS 105 105 105 HIS HIS A . n A 1 106 ASP 106 106 106 ASP ASP A . n A 1 107 THR 107 107 107 THR THR A . n A 1 108 LYS 108 108 108 LYS LYS A . n A 1 109 HIS 109 109 109 HIS HIS A . n A 1 110 ILE 110 110 110 ILE ILE A . n A 1 111 LEU 111 111 111 LEU LEU A . n A 1 112 SER 112 112 112 SER SER A . n A 1 113 ASN 113 113 113 ASN ASN A . n A 1 114 ALA 114 114 114 ALA ALA A . n A 1 115 LEU 115 115 115 LEU LEU A . n A 1 116 ARG 116 116 116 ARG ARG A . n A 1 117 HIS 117 117 117 HIS HIS A . n A 1 118 LEU 118 118 118 LEU LEU A . n A 1 119 HIS 119 119 119 HIS HIS A . n A 1 120 ASP 120 120 120 ASP ASP A . n A 1 121 ASN 121 121 121 ASN ASN A . n A 1 122 PRO 122 122 122 PRO PRO A . n A 1 123 GLU 123 123 123 GLU GLU A . n A 1 124 MET 124 124 124 MET MET A . n A 1 125 LYS 125 125 125 LYS LYS A . n A 1 126 PHE 126 126 126 PHE PHE A . n A 1 127 ILE 127 127 127 ILE ILE A . n A 1 128 TRP 128 128 128 TRP TRP A . n A 1 129 ALA 129 129 129 ALA ALA A . n A 1 130 GLU 130 130 130 GLU GLU A . n A 1 131 ILE 131 131 131 ILE ILE A . n A 1 132 SER 132 132 132 SER SER A . n A 1 133 TYR 133 133 133 TYR TYR A . n A 1 134 PHE 134 134 134 PHE PHE A . n A 1 135 ALA 135 135 135 ALA ALA A . n A 1 136 ARG 136 136 136 ARG ARG A . n A 1 137 PHE 137 137 137 PHE PHE A . n A 1 138 TYR 138 138 138 TYR TYR A . n A 1 139 HIS 139 139 139 HIS HIS A . n A 1 140 ASP 140 140 140 ASP ASP A . n A 1 141 LEU 141 141 141 LEU LEU A . n A 1 142 GLY 142 142 142 GLY GLY A . n A 1 143 GLU 143 143 143 GLU GLU A . n A 1 144 ASN 144 144 144 ASN ASN A . n A 1 145 LYS 145 145 145 LYS LYS A . n A 1 146 LYS 146 146 146 LYS LYS A . n A 1 147 LEU 147 147 147 LEU LEU A . n A 1 148 GLN 148 148 148 GLN GLN A . n A 1 149 MET 149 149 149 MET MET A . n A 1 150 LYS 150 150 150 LYS LYS A . n A 1 151 SER 151 151 151 SER SER A . n A 1 152 ILE 152 152 152 ILE ILE A . n A 1 153 VAL 153 153 153 VAL VAL A . n A 1 154 LYS 154 154 154 LYS LYS A . n A 1 155 ASN 155 155 155 ASN ASN A . n A 1 156 GLY 156 156 156 GLY GLY A . n A 1 157 GLN 157 157 157 GLN GLN A . n A 1 158 LEU 158 158 158 LEU LEU A . n A 1 159 GLU 159 159 159 GLU GLU A . n A 1 160 PHE 160 160 160 PHE PHE A . n A 1 161 VAL 161 161 161 VAL VAL A . n A 1 162 THR 162 162 162 THR THR A . n A 1 163 GLY 163 163 163 GLY GLY A . n A 1 164 GLY 164 164 164 GLY GLY A . n A 1 165 TRP 165 165 165 TRP TRP A . n A 1 166 VAL 166 166 166 VAL VAL A . n A 1 167 MET 167 167 167 MET MET A . n A 1 168 PRO 168 168 168 PRO PRO A . n A 1 169 ASP 169 169 169 ASP ASP A . n A 1 170 GLU 170 170 170 GLU GLU A . n A 1 171 ALA 171 171 171 ALA ALA A . n A 1 172 ASN 172 172 172 ASN ASN A . n A 1 173 SER 173 173 173 SER SER A . n A 1 174 HIS 174 174 174 HIS HIS A . n A 1 175 TRP 175 175 175 TRP TRP A . n A 1 176 ARG 176 176 176 ARG ARG A . n A 1 177 ASN 177 177 177 ASN ASN A . n A 1 178 VAL 178 178 178 VAL VAL A . n A 1 179 LEU 179 179 179 LEU LEU A . n A 1 180 LEU 180 180 180 LEU LEU A . n A 1 181 GLN 181 181 181 GLN GLN A . n A 1 182 LEU 182 182 182 LEU LEU A . n A 1 183 THR 183 183 183 THR THR A . n A 1 184 GLU 184 184 184 GLU GLU A . n A 1 185 GLY 185 185 185 GLY GLY A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 THR 187 187 187 THR THR A . n A 1 188 TRP 188 188 188 TRP TRP A . n A 1 189 LEU 189 189 189 LEU LEU A . n A 1 190 LYS 190 190 190 LYS LYS A . n A 1 191 GLN 191 191 191 GLN GLN A . n A 1 192 PHE 192 192 192 PHE PHE A . n A 1 193 MET 193 193 193 MET MET A . n A 1 194 ASN 194 194 194 ASN ASN A . n A 1 195 VAL 195 195 195 VAL VAL A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 PRO 197 197 197 PRO PRO A . n A 1 198 THR 198 198 198 THR THR A . n A 1 199 ALA 199 199 199 ALA ALA A . n A 1 200 SER 200 200 200 SER SER A . n A 1 201 TRP 201 201 201 TRP TRP A . n A 1 202 ALA 202 202 202 ALA ALA A . n A 1 203 ILE 203 203 203 ILE ILE A . n A 1 204 ASP 204 204 204 ASP ASP A . n A 1 205 PRO 205 205 205 PRO PRO A . n A 1 206 PHE 206 206 206 PHE PHE A . n A 1 207 GLY 207 207 207 GLY GLY A . n A 1 208 HIS 208 208 208 HIS HIS A . n A 1 209 SER 209 209 209 SER SER A . n A 1 210 PRO 210 210 210 PRO PRO A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 MET 212 212 212 MET MET A . n A 1 213 PRO 213 213 213 PRO PRO A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 ILE 215 215 215 ILE ILE A . n A 1 216 LEU 216 216 216 LEU LEU A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 LYS 218 218 218 LYS LYS A . n A 1 219 SER 219 219 219 SER SER A . n A 1 220 GLY 220 220 220 GLY GLY A . n A 1 221 PHE 221 221 221 PHE PHE A . n A 1 222 LYS 222 222 222 LYS LYS A . n A 1 223 ASN 223 223 223 ASN ASN A . n A 1 224 MET 224 224 224 MET MET A . n A 1 225 LEU 225 225 225 LEU LEU A . n A 1 226 ILE 226 226 226 ILE ILE A . n A 1 227 GLN 227 227 227 GLN GLN A . n A 1 228 ARG 228 228 228 ARG ARG A . n A 1 229 THR 229 229 229 THR THR A . n A 1 230 HIS 230 230 230 HIS HIS A . n A 1 231 TYR 231 231 231 TYR TYR A . n A 1 232 SER 232 232 232 SER SER A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 LYS 234 234 234 LYS LYS A . n A 1 235 LYS 235 235 235 LYS LYS A . n A 1 236 GLU 236 236 236 GLU GLU A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 ALA 238 238 238 ALA ALA A . n A 1 239 GLN 239 239 239 GLN GLN A . n A 1 240 GLN 240 240 240 GLN GLN A . n A 1 241 ARG 241 241 241 ARG ARG A . n A 1 242 GLN 242 242 242 GLN GLN A . n A 1 243 LEU 243 243 243 LEU LEU A . n A 1 244 GLU 244 244 244 GLU GLU A . n A 1 245 PHE 245 245 245 PHE PHE A . n A 1 246 LEU 246 246 246 LEU LEU A . n A 1 247 TRP 247 247 247 TRP TRP A . n A 1 248 ARG 248 248 248 ARG ARG A . n A 1 249 GLN 249 249 249 GLN GLN A . n A 1 250 ILE 250 250 250 ILE ILE A . n A 1 251 TRP 251 251 251 TRP TRP A . n A 1 252 ASP 252 252 252 ASP ASP A . n A 1 253 ASN 253 253 253 ASN ASN A . n A 1 254 LYS 254 254 254 LYS LYS A . n A 1 255 GLY 255 255 255 GLY GLY A . n A 1 256 ASP 256 256 256 ASP ASP A . n A 1 257 THR 257 257 257 THR THR A . n A 1 258 ALA 258 258 258 ALA ALA A . n A 1 259 LEU 259 259 259 LEU LEU A . n A 1 260 PHE 260 260 260 PHE PHE A . n A 1 261 THR 261 261 261 THR THR A . n A 1 262 HIS 262 262 262 HIS HIS A . n A 1 263 MET 263 263 263 MET MET A . n A 1 264 MET 264 264 264 MET MET A . n A 1 265 PRO 265 265 265 PRO PRO A . n A 1 266 PHE 266 266 266 PHE PHE A . n A 1 267 TYR 267 267 267 TYR TYR A . n A 1 268 SER 268 268 268 SER SER A . n A 1 269 TYR 269 269 269 TYR TYR A . n A 1 270 ASP 270 270 270 ASP ASP A . n A 1 271 ILE 271 271 271 ILE ILE A . n A 1 272 PRO 272 272 272 PRO PRO A . n A 1 273 HIS 273 273 273 HIS HIS A . n A 1 274 THR 274 274 274 THR THR A . n A 1 275 CYS 275 275 275 CYS CYS A . n A 1 276 GLY 276 276 276 GLY GLY A . n A 1 277 PRO 277 277 277 PRO PRO A . n A 1 278 ASP 278 278 278 ASP ASP A . n A 1 279 PRO 279 279 279 PRO PRO A . n A 1 280 LYS 280 280 280 LYS LYS A . n A 1 281 VAL 281 281 281 VAL VAL A . n A 1 282 CYS 282 282 282 CYS CYS A . n A 1 283 CYS 283 283 283 CYS CYS A . n A 1 284 GLN 284 284 284 GLN GLN A . n A 1 285 PHE 285 285 285 PHE PHE A . n A 1 286 ASP 286 286 286 ASP ASP A . n A 1 287 PHE 287 287 287 PHE PHE A . n A 1 288 LYS 288 288 288 LYS LYS A . n A 1 289 ARG 289 289 289 ARG ARG A . n A 1 290 MET 290 290 290 MET MET A . n A 1 291 GLY 291 291 291 GLY GLY A . n A 1 292 SER 292 292 292 SER SER A . n A 1 293 PHE 293 293 293 PHE PHE A . n A 1 294 GLY 294 294 294 GLY GLY A . n A 1 295 LEU 295 295 295 LEU LEU A . n A 1 296 SER 296 296 296 SER SER A . n A 1 297 CYS 297 297 297 CYS CYS A . n A 1 298 PRO 298 298 298 PRO PRO A . n A 1 299 TRP 299 299 299 TRP TRP A . n A 1 300 LYS 300 300 300 LYS LYS A . n A 1 301 VAL 301 301 301 VAL VAL A . n A 1 302 PRO 302 302 302 PRO PRO A . n A 1 303 PRO 303 303 303 PRO PRO A . n A 1 304 ARG 304 304 304 ARG ARG A . n A 1 305 THR 305 305 305 THR THR A . n A 1 306 ILE 306 306 306 ILE ILE A . n A 1 307 SER 307 307 307 SER SER A . n A 1 308 ASP 308 308 308 ASP ASP A . n A 1 309 GLN 309 309 309 GLN GLN A . n A 1 310 ASN 310 310 310 ASN ASN A . n A 1 311 VAL 311 311 311 VAL VAL A . n A 1 312 ALA 312 312 312 ALA ALA A . n A 1 313 ALA 313 313 313 ALA ALA A . n A 1 314 ARG 314 314 314 ARG ARG A . n A 1 315 SER 315 315 315 SER SER A . n A 1 316 ASP 316 316 316 ASP ASP A . n A 1 317 LEU 317 317 317 LEU LEU A . n A 1 318 LEU 318 318 318 LEU LEU A . n A 1 319 VAL 319 319 319 VAL VAL A . n A 1 320 ASP 320 320 320 ASP ASP A . n A 1 321 GLN 321 321 321 GLN GLN A . n A 1 322 TRP 322 322 322 TRP TRP A . n A 1 323 LYS 323 323 323 LYS LYS A . n A 1 324 LYS 324 324 324 LYS LYS A . n A 1 325 LYS 325 325 325 LYS LYS A . n A 1 326 ALA 326 326 326 ALA ALA A . n A 1 327 GLU 327 327 327 GLU GLU A . n A 1 328 LEU 328 328 328 LEU LEU A . n A 1 329 TYR 329 329 329 TYR TYR A . n A 1 330 ARG 330 330 330 ARG ARG A . n A 1 331 THR 331 331 331 THR THR A . n A 1 332 ASN 332 332 332 ASN ASN A . n A 1 333 VAL 333 333 333 VAL VAL A . n A 1 334 LEU 334 334 334 LEU LEU A . n A 1 335 LEU 335 335 335 LEU LEU A . n A 1 336 ILE 336 336 336 ILE ILE A . n A 1 337 PRO 337 337 337 PRO PRO A . n A 1 338 LEU 338 338 338 LEU LEU A . n A 1 339 GLY 339 339 339 GLY GLY A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 ASP 341 341 341 ASP ASP A . n A 1 342 PHE 342 342 342 PHE PHE A . n A 1 343 ARG 343 343 343 ARG ARG A . n A 1 344 PHE 344 344 344 PHE PHE A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 GLN 346 346 346 GLN GLN A . n A 1 347 ASN 347 347 347 ASN ASN A . n A 1 348 THR 348 348 348 THR THR A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 TRP 350 350 350 TRP TRP A . n A 1 351 ASP 351 351 351 ASP ASP A . n A 1 352 VAL 352 352 352 VAL VAL A . n A 1 353 GLN 353 353 353 GLN GLN A . n A 1 354 ARG 354 354 354 ARG ARG A . n A 1 355 VAL 355 355 355 VAL VAL A . n A 1 356 ASN 356 356 356 ASN ASN A . n A 1 357 TYR 357 357 357 TYR TYR A . n A 1 358 GLU 358 358 358 GLU GLU A . n A 1 359 ARG 359 359 359 ARG ARG A . n A 1 360 LEU 360 360 360 LEU LEU A . n A 1 361 PHE 361 361 361 PHE PHE A . n A 1 362 GLU 362 362 362 GLU GLU A . n A 1 363 HIS 363 363 363 HIS HIS A . n A 1 364 ILE 364 364 364 ILE ILE A . n A 1 365 ASN 365 365 365 ASN ASN A . n A 1 366 SER 366 366 366 SER SER A . n A 1 367 GLN 367 367 367 GLN GLN A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 HIS 369 369 369 HIS HIS A . n A 1 370 PHE 370 370 370 PHE PHE A . n A 1 371 ASN 371 371 371 ASN ASN A . n A 1 372 VAL 372 372 372 VAL VAL A . n A 1 373 GLN 373 373 373 GLN GLN A . n A 1 374 ALA 374 374 374 ALA ALA A . n A 1 375 GLN 375 375 375 GLN GLN A . n A 1 376 PHE 376 376 376 PHE PHE A . n A 1 377 GLY 377 377 377 GLY GLY A . n A 1 378 THR 378 378 378 THR THR A . n A 1 379 LEU 379 379 379 LEU LEU A . n A 1 380 GLN 380 380 380 GLN GLN A . n A 1 381 GLU 381 381 381 GLU GLU A . n A 1 382 TYR 382 382 382 TYR TYR A . n A 1 383 PHE 383 383 383 PHE PHE A . n A 1 384 ASP 384 384 384 ASP ASP A . n A 1 385 ALA 385 385 385 ALA ALA A . n A 1 386 VAL 386 386 386 VAL VAL A . n A 1 387 HIS 387 387 387 HIS HIS A . n A 1 388 GLN 388 388 388 GLN GLN A . n A 1 389 ALA 389 389 389 ALA ALA A . n A 1 390 GLU 390 390 390 GLU GLU A . n A 1 391 ARG 391 391 391 ARG ARG A . n A 1 392 ALA 392 392 392 ALA ALA A . n A 1 393 GLY 393 393 393 GLY GLY A . n A 1 394 GLN 394 394 394 GLN GLN A . n A 1 395 ALA 395 395 395 ALA ALA A . n A 1 396 GLU 396 396 396 GLU GLU A . n A 1 397 PHE 397 397 397 PHE PHE A . n A 1 398 PRO 398 398 398 PRO PRO A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 LEU 400 400 400 LEU LEU A . n A 1 401 SER 401 401 401 SER SER A . n A 1 402 GLY 402 402 402 GLY GLY A . n A 1 403 ASP 403 403 403 ASP ASP A . n A 1 404 PHE 404 404 404 PHE PHE A . n A 1 405 PHE 405 405 405 PHE PHE A . n A 1 406 THR 406 406 406 THR THR A . n A 1 407 TYR 407 407 407 TYR TYR A . n A 1 408 ALA 408 408 408 ALA ALA A . n A 1 409 ASP 409 409 409 ASP ASP A . n A 1 410 ARG 410 410 410 ARG ARG A . n A 1 411 SER 411 411 411 SER SER A . n A 1 412 ASP 412 412 412 ASP ASP A . n A 1 413 ASN 413 413 413 ASN ASN A . n A 1 414 TYR 414 414 414 TYR TYR A . n A 1 415 TRP 415 415 415 TRP TRP A . n A 1 416 SER 416 416 416 SER SER A . n A 1 417 GLY 417 417 417 GLY GLY A . n A 1 418 TYR 418 418 418 TYR TYR A . n A 1 419 TYR 419 419 419 TYR TYR A . n A 1 420 THR 420 420 420 THR THR A . n A 1 421 SER 421 421 421 SER SER A . n A 1 422 ARG 422 422 422 ARG ARG A . n A 1 423 PRO 423 423 423 PRO PRO A . n A 1 424 TYR 424 424 424 TYR TYR A . n A 1 425 HIS 425 425 425 HIS HIS A . n A 1 426 LYS 426 426 426 LYS LYS A . n A 1 427 ARG 427 427 427 ARG ARG A . n A 1 428 MET 428 428 428 MET MET A . n A 1 429 ASP 429 429 429 ASP ASP A . n A 1 430 ARG 430 430 430 ARG ARG A . n A 1 431 VAL 431 431 431 VAL VAL A . n A 1 432 LEU 432 432 432 LEU LEU A . n A 1 433 MET 433 433 433 MET MET A . n A 1 434 HIS 434 434 434 HIS HIS A . n A 1 435 TYR 435 435 435 TYR TYR A . n A 1 436 VAL 436 436 436 VAL VAL A . n A 1 437 ARG 437 437 437 ARG ARG A . n A 1 438 ALA 438 438 438 ALA ALA A . n A 1 439 ALA 439 439 439 ALA ALA A . n A 1 440 GLU 440 440 440 GLU GLU A . n A 1 441 MET 441 441 441 MET MET A . n A 1 442 LEU 442 442 442 LEU LEU A . n A 1 443 SER 443 443 443 SER SER A . n A 1 444 ALA 444 444 444 ALA ALA A . n A 1 445 TRP 445 445 445 TRP TRP A . n A 1 446 HIS 446 446 446 HIS HIS A . n A 1 447 SER 447 447 447 SER SER A . n A 1 448 TRP 448 448 448 TRP TRP A . n A 1 449 ASP 449 449 449 ASP ASP A . n A 1 450 GLY 450 450 450 GLY GLY A . n A 1 451 MET 451 451 451 MET MET A . n A 1 452 ALA 452 452 452 ALA ALA A . n A 1 453 ARG 453 453 453 ARG ARG A . n A 1 454 ILE 454 454 454 ILE ILE A . n A 1 455 GLU 455 455 455 GLU GLU A . n A 1 456 GLU 456 456 456 GLU GLU A . n A 1 457 ARG 457 457 457 ARG ARG A . n A 1 458 LEU 458 458 458 LEU LEU A . n A 1 459 GLU 459 459 459 GLU GLU A . n A 1 460 GLN 460 460 460 GLN GLN A . n A 1 461 ALA 461 461 461 ALA ALA A . n A 1 462 ARG 462 462 462 ARG ARG A . n A 1 463 ARG 463 463 463 ARG ARG A . n A 1 464 GLU 464 464 464 GLU GLU A . n A 1 465 LEU 465 465 465 LEU LEU A . n A 1 466 SER 466 466 466 SER SER A . n A 1 467 LEU 467 467 467 LEU LEU A . n A 1 468 PHE 468 468 468 PHE PHE A . n A 1 469 GLN 469 469 469 GLN GLN A . n A 1 470 HIS 470 470 470 HIS HIS A . n A 1 471 HIS 471 471 471 HIS HIS A . n A 1 472 ASP 472 472 472 ASP ASP A . n A 1 473 GLY 473 473 473 GLY GLY A . n A 1 474 ILE 474 474 474 ILE ILE A . n A 1 475 THR 475 475 475 THR THR A . n A 1 476 GLY 476 476 476 GLY GLY A . n A 1 477 THR 477 477 477 THR THR A . n A 1 478 ALA 478 478 478 ALA ALA A . n A 1 479 LYS 479 479 479 LYS LYS A . n A 1 480 THR 480 480 480 THR THR A . n A 1 481 HIS 481 481 481 HIS HIS A . n A 1 482 VAL 482 482 482 VAL VAL A . n A 1 483 VAL 483 483 483 VAL VAL A . n A 1 484 VAL 484 484 484 VAL VAL A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 TYR 486 486 486 TYR TYR A . n A 1 487 GLU 487 487 487 GLU GLU A . n A 1 488 GLN 488 488 488 GLN GLN A . n A 1 489 ARG 489 489 489 ARG ARG A . n A 1 490 MET 490 490 490 MET MET A . n A 1 491 GLN 491 491 491 GLN GLN A . n A 1 492 GLU 492 492 492 GLU GLU A . n A 1 493 ALA 493 493 493 ALA ALA A . n A 1 494 LEU 494 494 494 LEU LEU A . n A 1 495 LYS 495 495 495 LYS LYS A . n A 1 496 ALA 496 496 496 ALA ALA A . n A 1 497 CYS 497 497 497 CYS CYS A . n A 1 498 GLN 498 498 498 GLN GLN A . n A 1 499 MET 499 499 499 MET MET A . n A 1 500 VAL 500 500 500 VAL VAL A . n A 1 501 MET 501 501 501 MET MET A . n A 1 502 GLN 502 502 502 GLN GLN A . n A 1 503 GLN 503 503 503 GLN GLN A . n A 1 504 SER 504 504 504 SER SER A . n A 1 505 VAL 505 505 505 VAL VAL A . n A 1 506 TYR 506 506 506 TYR TYR A . n A 1 507 ARG 507 507 507 ARG ARG A . n A 1 508 LEU 508 508 508 LEU LEU A . n A 1 509 LEU 509 509 509 LEU LEU A . n A 1 510 THR 510 510 510 THR THR A . n A 1 511 LYS 511 511 511 LYS LYS A . n A 1 512 PRO 512 512 512 PRO PRO A . n A 1 513 SER 513 513 513 SER SER A . n A 1 514 ILE 514 514 514 ILE ILE A . n A 1 515 TYR 515 515 515 TYR TYR A . n A 1 516 SER 516 516 516 SER SER A . n A 1 517 PRO 517 517 517 PRO PRO A . n A 1 518 ASP 518 518 518 ASP ASP A . n A 1 519 PHE 519 519 519 PHE PHE A . n A 1 520 SER 520 520 520 SER SER A . n A 1 521 PHE 521 521 521 PHE PHE A . n A 1 522 SER 522 522 522 SER SER A . n A 1 523 TYR 523 523 523 TYR TYR A . n A 1 524 PHE 524 524 524 PHE PHE A . n A 1 525 THR 525 525 525 THR THR A . n A 1 526 LEU 526 526 526 LEU LEU A . n A 1 527 ASP 527 527 527 ASP ASP A . n A 1 528 ASP 528 528 528 ASP ASP A . n A 1 529 SER 529 529 529 SER SER A . n A 1 530 ARG 530 530 530 ARG ARG A . n A 1 531 TRP 531 531 531 TRP TRP A . n A 1 532 PRO 532 532 532 PRO PRO A . n A 1 533 GLY 533 533 533 GLY GLY A . n A 1 534 SER 534 534 534 SER SER A . n A 1 535 GLY 535 535 535 GLY GLY A . n A 1 536 VAL 536 536 536 VAL VAL A . n A 1 537 GLU 537 537 537 GLU GLU A . n A 1 538 ASP 538 538 538 ASP ASP A . n A 1 539 SER 539 539 539 SER SER A . n A 1 540 ARG 540 540 540 ARG ARG A . n A 1 541 THR 541 541 541 THR THR A . n A 1 542 THR 542 542 542 THR THR A . n A 1 543 ILE 543 543 543 ILE ILE A . n A 1 544 ILE 544 544 544 ILE ILE A . n A 1 545 LEU 545 545 545 LEU LEU A . n A 1 546 GLY 546 546 546 GLY GLY A . n A 1 547 GLU 547 547 547 GLU GLU A . n A 1 548 ASP 548 548 548 ASP ASP A . n A 1 549 ILE 549 549 549 ILE ILE A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 PRO 551 551 551 PRO PRO A . n A 1 552 SER 552 552 552 SER SER A . n A 1 553 LYS 553 553 553 LYS LYS A . n A 1 554 HIS 554 554 554 HIS HIS A . n A 1 555 VAL 555 555 555 VAL VAL A . n A 1 556 VAL 556 556 556 VAL VAL A . n A 1 557 MET 557 557 557 MET MET A . n A 1 558 HIS 558 558 558 HIS HIS A . n A 1 559 ASN 559 559 559 ASN ASN A . n A 1 560 THR 560 560 560 THR THR A . n A 1 561 LEU 561 561 561 LEU LEU A . n A 1 562 PRO 562 562 562 PRO PRO A . n A 1 563 HIS 563 563 563 HIS HIS A . n A 1 564 TRP 564 564 564 TRP TRP A . n A 1 565 ARG 565 565 565 ARG ARG A . n A 1 566 GLU 566 566 566 GLU GLU A . n A 1 567 GLN 567 567 567 GLN GLN A . n A 1 568 LEU 568 568 568 LEU LEU A . n A 1 569 VAL 569 569 569 VAL VAL A . n A 1 570 ASP 570 570 570 ASP ASP A . n A 1 571 PHE 571 571 571 PHE PHE A . n A 1 572 TYR 572 572 572 TYR TYR A . n A 1 573 VAL 573 573 573 VAL VAL A . n A 1 574 SER 574 574 574 SER SER A . n A 1 575 SER 575 575 575 SER SER A . n A 1 576 PRO 576 576 576 PRO PRO A . n A 1 577 PHE 577 577 577 PHE PHE A . n A 1 578 VAL 578 578 578 VAL VAL A . n A 1 579 SER 579 579 579 SER SER A . n A 1 580 VAL 580 580 580 VAL VAL A . n A 1 581 THR 581 581 581 THR THR A . n A 1 582 ASP 582 582 582 ASP ASP A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 ALA 584 584 584 ALA ALA A . n A 1 585 ASN 585 585 585 ASN ASN A . n A 1 586 ASN 586 586 586 ASN ASN A . n A 1 587 PRO 587 587 587 PRO PRO A . n A 1 588 VAL 588 588 588 VAL VAL A . n A 1 589 GLU 589 589 589 GLU GLU A . n A 1 590 ALA 590 590 590 ALA ALA A . n A 1 591 GLN 591 591 591 GLN GLN A . n A 1 592 VAL 592 592 592 VAL VAL A . n A 1 593 SER 593 593 593 SER SER A . n A 1 594 PRO 594 594 594 PRO PRO A . n A 1 595 VAL 595 595 595 VAL VAL A . n A 1 596 TRP 596 596 596 TRP TRP A . n A 1 597 SER 597 597 597 SER SER A . n A 1 598 TRP 598 598 598 TRP TRP A . n A 1 599 HIS 599 599 599 HIS HIS A . n A 1 600 HIS 600 600 600 HIS HIS A . n A 1 601 ASP 601 601 601 ASP ASP A . n A 1 602 THR 602 602 602 THR THR A . n A 1 603 LEU 603 603 603 LEU LEU A . n A 1 604 THR 604 604 604 THR THR A . n A 1 605 LYS 605 605 605 LYS LYS A . n A 1 606 THR 606 606 606 THR THR A . n A 1 607 ILE 607 607 607 ILE ILE A . n A 1 608 HIS 608 608 608 HIS HIS A . n A 1 609 PRO 609 609 609 PRO PRO A . n A 1 610 GLN 610 610 610 GLN GLN A . n A 1 611 GLY 611 611 611 GLY GLY A . n A 1 612 SER 612 612 612 SER SER A . n A 1 613 THR 613 613 613 THR THR A . n A 1 614 THR 614 614 614 THR THR A . n A 1 615 LYS 615 615 615 LYS LYS A . n A 1 616 TYR 616 616 616 TYR TYR A . n A 1 617 ARG 617 617 617 ARG ARG A . n A 1 618 ILE 618 618 618 ILE ILE A . n A 1 619 ILE 619 619 619 ILE ILE A . n A 1 620 PHE 620 620 620 PHE PHE A . n A 1 621 LYS 621 621 621 LYS LYS A . n A 1 622 ALA 622 622 622 ALA ALA A . n A 1 623 ARG 623 623 623 ARG ARG A . n A 1 624 VAL 624 624 624 VAL VAL A . n A 1 625 PRO 625 625 625 PRO PRO A . n A 1 626 PRO 626 626 626 PRO PRO A . n A 1 627 MET 627 627 627 MET MET A . n A 1 628 GLY 628 628 628 GLY GLY A . n A 1 629 LEU 629 629 629 LEU LEU A . n A 1 630 ALA 630 630 630 ALA ALA A . n A 1 631 THR 631 631 631 THR THR A . n A 1 632 TYR 632 632 632 TYR TYR A . n A 1 633 VAL 633 633 633 VAL VAL A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 THR 635 635 635 THR THR A . n A 1 636 ILE 636 636 636 ILE ILE A . n A 1 637 SER 637 637 637 SER SER A . n A 1 638 ASP 638 638 638 ASP ASP A . n A 1 639 SER 639 639 639 SER SER A . n A 1 640 LYS 640 640 640 LYS LYS A . n A 1 641 PRO 641 641 641 PRO PRO A . n A 1 642 GLU 642 642 642 GLU GLU A . n A 1 643 HIS 643 643 643 HIS HIS A . n A 1 644 THR 644 644 644 THR THR A . n A 1 645 SER 645 645 645 SER SER A . n A 1 646 TYR 646 646 646 TYR TYR A . n A 1 647 ALA 647 647 647 ALA ALA A . n A 1 648 SER 648 648 648 SER SER A . n A 1 649 ASN 649 649 649 ASN ASN A . n A 1 650 LEU 650 650 650 LEU LEU A . n A 1 651 LEU 651 651 651 LEU LEU A . n A 1 652 LEU 652 652 652 LEU LEU A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 LYS 654 654 654 LYS LYS A . n A 1 655 ASN 655 655 655 ASN ASN A . n A 1 656 PRO 656 656 656 PRO PRO A . n A 1 657 THR 657 657 657 THR THR A . n A 1 658 SER 658 658 658 SER SER A . n A 1 659 LEU 659 659 659 LEU LEU A . n A 1 660 PRO 660 660 660 PRO PRO A . n A 1 661 LEU 661 661 661 LEU LEU A . n A 1 662 GLY 662 662 662 GLY GLY A . n A 1 663 GLN 663 663 663 GLN GLN A . n A 1 664 TYR 664 664 664 TYR TYR A . n A 1 665 PRO 665 665 665 PRO PRO A . n A 1 666 GLU 666 666 666 GLU GLU A . n A 1 667 ASP 667 667 667 ASP ASP A . n A 1 668 VAL 668 668 668 VAL VAL A . n A 1 669 LYS 669 669 669 LYS LYS A . n A 1 670 PHE 670 670 670 PHE PHE A . n A 1 671 GLY 671 671 671 GLY GLY A . n A 1 672 ASP 672 672 672 ASP ASP A . n A 1 673 PRO 673 673 673 PRO PRO A . n A 1 674 ARG 674 674 674 ARG ARG A . n A 1 675 GLU 675 675 675 GLU GLU A . n A 1 676 ILE 676 676 676 ILE ILE A . n A 1 677 SER 677 677 677 SER SER A . n A 1 678 LEU 678 678 678 LEU LEU A . n A 1 679 ARG 679 679 679 ARG ARG A . n A 1 680 VAL 680 680 680 VAL VAL A . n A 1 681 GLY 681 681 681 GLY GLY A . n A 1 682 ASN 682 682 682 ASN ASN A . n A 1 683 GLY 683 683 683 GLY GLY A . n A 1 684 PRO 684 684 684 PRO PRO A . n A 1 685 THR 685 685 685 THR THR A . n A 1 686 LEU 686 686 686 LEU LEU A . n A 1 687 ALA 687 687 687 ALA ALA A . n A 1 688 PHE 688 688 688 PHE PHE A . n A 1 689 SER 689 689 689 SER SER A . n A 1 690 GLU 690 690 690 GLU GLU A . n A 1 691 GLN 691 691 691 GLN GLN A . n A 1 692 GLY 692 692 692 GLY GLY A . n A 1 693 LEU 693 693 693 LEU LEU A . n A 1 694 LEU 694 694 694 LEU LEU A . n A 1 695 LYS 695 695 695 LYS LYS A . n A 1 696 SER 696 696 696 SER SER A . n A 1 697 ILE 697 697 697 ILE ILE A . n A 1 698 GLN 698 698 698 GLN GLN A . n A 1 699 LEU 699 699 699 LEU LEU A . n A 1 700 THR 700 700 700 THR THR A . n A 1 701 GLN 701 701 701 GLN GLN A . n A 1 702 ASP 702 702 702 ASP ASP A . n A 1 703 SER 703 703 703 SER SER A . n A 1 704 PRO 704 704 704 PRO PRO A . n A 1 705 HIS 705 705 705 HIS HIS A . n A 1 706 VAL 706 706 706 VAL VAL A . n A 1 707 PRO 707 707 707 PRO PRO A . n A 1 708 VAL 708 708 708 VAL VAL A . n A 1 709 HIS 709 709 709 HIS HIS A . n A 1 710 PHE 710 710 710 PHE PHE A . n A 1 711 LYS 711 711 711 LYS LYS A . n A 1 712 PHE 712 712 712 PHE PHE A . n A 1 713 LEU 713 713 713 LEU LEU A . n A 1 714 LYS 714 714 714 LYS LYS A . n A 1 715 TYR 715 715 715 TYR TYR A . n A 1 716 GLY 716 716 716 GLY GLY A . n A 1 717 VAL 717 717 717 VAL VAL A . n A 1 718 ARG 718 718 718 ARG ARG A . n A 1 719 SER 719 719 719 SER SER A . n A 1 720 HIS 720 720 720 HIS HIS A . n A 1 721 GLY 721 721 721 GLY GLY A . n A 1 722 ASP 722 722 722 ASP ASP A . n A 1 723 ARG 723 723 723 ARG ARG A . n A 1 724 SER 724 724 724 SER SER A . n A 1 725 GLY 725 725 725 GLY GLY A . n A 1 726 ALA 726 726 726 ALA ALA A . n A 1 727 TYR 727 727 727 TYR TYR A . n A 1 728 LEU 728 728 728 LEU LEU A . n A 1 729 PHE 729 729 729 PHE PHE A . n A 1 730 LEU 730 730 730 LEU LEU A . n A 1 731 PRO 731 731 731 PRO PRO A . n A 1 732 ASN 732 732 732 ASN ASN A . n A 1 733 GLY 733 733 733 GLY GLY A . n A 1 734 PRO 734 734 734 PRO PRO A . n A 1 735 ALA 735 735 735 ALA ALA A . n A 1 736 SER 736 736 736 SER SER A . n A 1 737 PRO 737 737 737 PRO PRO A . n A 1 738 VAL 738 738 738 VAL VAL A . n A 1 739 GLU 739 739 739 GLU GLU A . n A 1 740 LEU 740 740 740 LEU LEU A . n A 1 741 GLY 741 741 741 GLY GLY A . n A 1 742 GLN 742 742 742 GLN GLN A . n A 1 743 PRO 743 743 743 PRO PRO A . n A 1 744 VAL 744 744 744 VAL VAL A . n A 1 745 VAL 745 745 745 VAL VAL A . n A 1 746 LEU 746 746 746 LEU LEU A . n A 1 747 VAL 747 747 747 VAL VAL A . n A 1 748 THR 748 748 748 THR THR A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 GLY 750 750 750 GLY GLY A . n A 1 751 LYS 751 751 751 LYS LYS A . n A 1 752 LEU 752 752 752 LEU LEU A . n A 1 753 GLU 753 753 753 GLU GLU A . n A 1 754 SER 754 754 754 SER SER A . n A 1 755 SER 755 755 755 SER SER A . n A 1 756 VAL 756 756 756 VAL VAL A . n A 1 757 SER 757 757 757 SER SER A . n A 1 758 VAL 758 758 758 VAL VAL A . n A 1 759 GLY 759 759 759 GLY GLY A . n A 1 760 LEU 760 760 760 LEU LEU A . n A 1 761 PRO 761 761 761 PRO PRO A . n A 1 762 SER 762 762 762 SER SER A . n A 1 763 VAL 763 763 763 VAL VAL A . n A 1 764 VAL 764 764 764 VAL VAL A . n A 1 765 HIS 765 765 765 HIS HIS A . n A 1 766 GLN 766 766 766 GLN GLN A . n A 1 767 THR 767 767 767 THR THR A . n A 1 768 ILE 768 768 768 ILE ILE A . n A 1 769 MET 769 769 769 MET MET A . n A 1 770 ARG 770 770 770 ARG ARG A . n A 1 771 GLY 771 771 771 GLY GLY A . n A 1 772 GLY 772 772 772 GLY GLY A . n A 1 773 ALA 773 773 773 ALA ALA A . n A 1 774 PRO 774 774 774 PRO PRO A . n A 1 775 GLU 775 775 775 GLU GLU A . n A 1 776 ILE 776 776 776 ILE ILE A . n A 1 777 ARG 777 777 777 ARG ARG A . n A 1 778 ASN 778 778 778 ASN ASN A . n A 1 779 LEU 779 779 779 LEU LEU A . n A 1 780 VAL 780 780 780 VAL VAL A . n A 1 781 ASP 781 781 781 ASP ASP A . n A 1 782 ILE 782 782 782 ILE ILE A . n A 1 783 GLY 783 783 783 GLY GLY A . n A 1 784 SER 784 784 784 SER SER A . n A 1 785 LEU 785 785 785 LEU LEU A . n A 1 786 ASP 786 786 786 ASP ASP A . n A 1 787 ASN 787 787 787 ASN ASN A . n A 1 788 THR 788 788 788 THR THR A . n A 1 789 GLU 789 789 789 GLU GLU A . n A 1 790 ILE 790 790 790 ILE ILE A . n A 1 791 VAL 791 791 791 VAL VAL A . n A 1 792 MET 792 792 792 MET MET A . n A 1 793 ARG 793 793 793 ARG ARG A . n A 1 794 LEU 794 794 794 LEU LEU A . n A 1 795 GLU 795 795 795 GLU GLU A . n A 1 796 THR 796 796 796 THR THR A . n A 1 797 HIS 797 797 797 HIS HIS A . n A 1 798 ILE 798 798 798 ILE ILE A . n A 1 799 ASP 799 799 799 ASP ASP A . n A 1 800 SER 800 800 800 SER SER A . n A 1 801 GLY 801 801 801 GLY GLY A . n A 1 802 ASP 802 802 802 ASP ASP A . n A 1 803 ILE 803 803 803 ILE ILE A . n A 1 804 PHE 804 804 804 PHE PHE A . n A 1 805 TYR 805 805 805 TYR TYR A . n A 1 806 THR 806 806 806 THR THR A . n A 1 807 ASP 807 807 807 ASP ASP A . n A 1 808 LEU 808 808 808 LEU LEU A . n A 1 809 ASN 809 809 809 ASN ASN A . n A 1 810 GLY 810 810 810 GLY GLY A . n A 1 811 LEU 811 811 811 LEU LEU A . n A 1 812 GLN 812 812 812 GLN GLN A . n A 1 813 PHE 813 813 813 PHE PHE A . n A 1 814 ILE 814 814 814 ILE ILE A . n A 1 815 LYS 815 815 815 LYS LYS A . n A 1 816 ARG 816 816 816 ARG ARG A . n A 1 817 ARG 817 817 817 ARG ARG A . n A 1 818 ARG 818 818 818 ARG ARG A . n A 1 819 LEU 819 819 819 LEU LEU A . n A 1 820 ASP 820 820 820 ASP ASP A . n A 1 821 LYS 821 821 821 LYS LYS A . n A 1 822 LEU 822 822 822 LEU LEU A . n A 1 823 PRO 823 823 823 PRO PRO A . n A 1 824 LEU 824 824 824 LEU LEU A . n A 1 825 GLN 825 825 825 GLN GLN A . n A 1 826 ALA 826 826 826 ALA ALA A . n A 1 827 ASN 827 827 827 ASN ASN A . n A 1 828 TYR 828 828 828 TYR TYR A . n A 1 829 TYR 829 829 829 TYR TYR A . n A 1 830 PRO 830 830 830 PRO PRO A . n A 1 831 ILE 831 831 831 ILE ILE A . n A 1 832 PRO 832 832 832 PRO PRO A . n A 1 833 SER 833 833 833 SER SER A . n A 1 834 GLY 834 834 834 GLY GLY A . n A 1 835 MET 835 835 835 MET MET A . n A 1 836 PHE 836 836 836 PHE PHE A . n A 1 837 ILE 837 837 837 ILE ILE A . n A 1 838 GLU 838 838 838 GLU GLU A . n A 1 839 ASP 839 839 839 ASP ASP A . n A 1 840 ALA 840 840 840 ALA ALA A . n A 1 841 ASN 841 841 841 ASN ASN A . n A 1 842 THR 842 842 842 THR THR A . n A 1 843 ARG 843 843 843 ARG ARG A . n A 1 844 LEU 844 844 844 LEU LEU A . n A 1 845 THR 845 845 845 THR THR A . n A 1 846 LEU 846 846 846 LEU LEU A . n A 1 847 LEU 847 847 847 LEU LEU A . n A 1 848 THR 848 848 848 THR THR A . n A 1 849 GLY 849 849 849 GLY GLY A . n A 1 850 GLN 850 850 850 GLN GLN A . n A 1 851 PRO 851 851 851 PRO PRO A . n A 1 852 LEU 852 852 852 LEU LEU A . n A 1 853 GLY 853 853 853 GLY GLY A . n A 1 854 GLY 854 854 854 GLY GLY A . n A 1 855 SER 855 855 855 SER SER A . n A 1 856 SER 856 856 856 SER SER A . n A 1 857 LEU 857 857 857 LEU LEU A . n A 1 858 ALA 858 858 858 ALA ALA A . n A 1 859 SER 859 859 859 SER SER A . n A 1 860 GLY 860 860 860 GLY GLY A . n A 1 861 GLU 861 861 861 GLU GLU A . n A 1 862 LEU 862 862 862 LEU LEU A . n A 1 863 GLU 863 863 863 GLU GLU A . n A 1 864 ILE 864 864 864 ILE ILE A . n A 1 865 MET 865 865 865 MET MET A . n A 1 866 GLN 866 866 866 GLN GLN A . n A 1 867 ASP 867 867 867 ASP ASP A . n A 1 868 ARG 868 868 868 ARG ARG A . n A 1 869 ARG 869 869 869 ARG ARG A . n A 1 870 LEU 870 870 870 LEU LEU A . n A 1 871 ALA 871 871 871 ALA ALA A . n A 1 872 SER 872 872 872 SER SER A . n A 1 873 ASP 873 873 873 ASP ASP A . n A 1 874 ASP 874 874 874 ASP ASP A . n A 1 875 GLU 875 875 875 GLU GLU A . n A 1 876 ARG 876 876 876 ARG ARG A . n A 1 877 GLY 877 877 877 GLY GLY A . n A 1 878 LEU 878 878 878 LEU LEU A . n A 1 879 GLY 879 879 879 GLY GLY A . n A 1 880 GLN 880 880 880 GLN GLN A . n A 1 881 GLY 881 881 881 GLY GLY A . n A 1 882 VAL 882 882 882 VAL VAL A . n A 1 883 LEU 883 883 883 LEU LEU A . n A 1 884 ASP 884 884 884 ASP ASP A . n A 1 885 ASN 885 885 885 ASN ASN A . n A 1 886 LYS 886 886 886 LYS LYS A . n A 1 887 PRO 887 887 887 PRO PRO A . n A 1 888 VAL 888 888 888 VAL VAL A . n A 1 889 LEU 889 889 889 LEU LEU A . n A 1 890 HIS 890 890 890 HIS HIS A . n A 1 891 ILE 891 891 891 ILE ILE A . n A 1 892 TYR 892 892 892 TYR TYR A . n A 1 893 ARG 893 893 893 ARG ARG A . n A 1 894 LEU 894 894 894 LEU LEU A . n A 1 895 VAL 895 895 895 VAL VAL A . n A 1 896 LEU 896 896 896 LEU LEU A . n A 1 897 GLU 897 897 897 GLU GLU A . n A 1 898 LYS 898 898 898 LYS LYS A . n A 1 899 VAL 899 899 899 VAL VAL A . n A 1 900 ASN 900 900 900 ASN ASN A . n A 1 901 ASN 901 901 901 ASN ASN A . n A 1 902 CYS 902 902 902 CYS CYS A . n A 1 903 VAL 903 903 903 VAL VAL A . n A 1 904 ARG 904 904 904 ARG ARG A . n A 1 905 PRO 905 905 905 PRO PRO A . n A 1 906 SER 906 906 906 SER SER A . n A 1 907 LYS 907 907 907 LYS LYS A . n A 1 908 LEU 908 908 908 LEU LEU A . n A 1 909 HIS 909 909 909 HIS HIS A . n A 1 910 PRO 910 910 910 PRO PRO A . n A 1 911 ALA 911 911 911 ALA ALA A . n A 1 912 GLY 912 912 912 GLY GLY A . n A 1 913 TYR 913 913 913 TYR TYR A . n A 1 914 LEU 914 914 914 LEU LEU A . n A 1 915 THR 915 915 915 THR THR A . n A 1 916 SER 916 916 916 SER SER A . n A 1 917 ALA 917 917 917 ALA ALA A . n A 1 918 ALA 918 918 918 ALA ALA A . n A 1 919 HIS 919 919 919 HIS HIS A . n A 1 920 LYS 920 920 920 LYS LYS A . n A 1 921 ALA 921 921 921 ALA ALA A . n A 1 922 SER 922 922 922 SER SER A . n A 1 923 GLN 923 923 923 GLN GLN A . n A 1 924 SER 924 924 924 SER SER A . n A 1 925 LEU 925 925 925 LEU LEU A . n A 1 926 LEU 926 926 926 LEU LEU A . n A 1 927 ASP 927 927 927 ASP ASP A . n A 1 928 PRO 928 928 928 PRO PRO A . n A 1 929 LEU 929 929 929 LEU LEU A . n A 1 930 ASP 930 930 930 ASP ASP A . n A 1 931 LYS 931 931 931 LYS LYS A . n A 1 932 PHE 932 932 932 PHE PHE A . n A 1 933 ILE 933 933 933 ILE ILE A . n A 1 934 PHE 934 934 934 PHE PHE A . n A 1 935 ALA 935 935 935 ALA ALA A . n A 1 936 GLU 936 936 936 GLU GLU A . n A 1 937 ASN 937 937 937 ASN ASN A . n A 1 938 GLU 938 938 938 GLU GLU A . n A 1 939 TRP 939 939 939 TRP TRP A . n A 1 940 ILE 940 940 940 ILE ILE A . n A 1 941 GLY 941 941 941 GLY GLY A . n A 1 942 ALA 942 942 942 ALA ALA A . n A 1 943 GLN 943 943 943 GLN GLN A . n A 1 944 GLY 944 944 944 GLY GLY A . n A 1 945 GLN 945 945 945 GLN GLN A . n A 1 946 PHE 946 946 946 PHE PHE A . n A 1 947 GLY 947 947 947 GLY GLY A . n A 1 948 GLY 948 948 948 GLY GLY A . n A 1 949 ASP 949 949 949 ASP ASP A . n A 1 950 HIS 950 950 950 HIS HIS A . n A 1 951 PRO 951 951 951 PRO PRO A . n A 1 952 SER 952 952 952 SER SER A . n A 1 953 ALA 953 953 953 ALA ALA A . n A 1 954 ARG 954 954 954 ARG ARG A . n A 1 955 GLU 955 955 955 GLU GLU A . n A 1 956 ASP 956 956 956 ASP ASP A . n A 1 957 LEU 957 957 957 LEU LEU A . n A 1 958 ASP 958 958 958 ASP ASP A . n A 1 959 VAL 959 959 959 VAL VAL A . n A 1 960 SER 960 960 960 SER SER A . n A 1 961 VAL 961 961 961 VAL VAL A . n A 1 962 MET 962 962 962 MET MET A . n A 1 963 ARG 963 963 963 ARG ARG A . n A 1 964 ARG 964 964 964 ARG ARG A . n A 1 965 LEU 965 965 965 LEU LEU A . n A 1 966 THR 966 966 966 THR THR A . n A 1 967 LYS 967 967 967 LYS LYS A . n A 1 968 SER 968 968 968 SER SER A . n A 1 969 SER 969 969 969 SER SER A . n A 1 970 ALA 970 970 970 ALA ALA A . n A 1 971 LYS 971 971 971 LYS LYS A . n A 1 972 THR 972 972 972 THR THR A . n A 1 973 GLN 973 973 973 GLN GLN A . n A 1 974 ARG 974 974 974 ARG ARG A . n A 1 975 VAL 975 975 975 VAL VAL A . n A 1 976 GLY 976 976 976 GLY GLY A . n A 1 977 TYR 977 977 977 TYR TYR A . n A 1 978 VAL 978 978 978 VAL VAL A . n A 1 979 LEU 979 979 979 LEU LEU A . n A 1 980 HIS 980 980 980 HIS HIS A . n A 1 981 ARG 981 981 981 ARG ARG A . n A 1 982 THR 982 982 982 THR THR A . n A 1 983 ASN 983 983 983 ASN ASN A . n A 1 984 LEU 984 984 984 LEU LEU A . n A 1 985 MET 985 985 985 MET MET A . n A 1 986 GLN 986 986 986 GLN GLN A . n A 1 987 CYS 987 987 987 CYS CYS A . n A 1 988 GLY 988 988 988 GLY GLY A . n A 1 989 THR 989 989 989 THR THR A . n A 1 990 PRO 990 990 990 PRO PRO A . n A 1 991 GLU 991 991 991 GLU GLU A . n A 1 992 GLU 992 992 992 GLU GLU A . n A 1 993 HIS 993 993 993 HIS HIS A . n A 1 994 THR 994 994 994 THR THR A . n A 1 995 GLN 995 995 995 GLN GLN A . n A 1 996 LYS 996 996 996 LYS LYS A . n A 1 997 LEU 997 997 997 LEU LEU A . n A 1 998 ASP 998 998 998 ASP ASP A . n A 1 999 VAL 999 999 999 VAL VAL A . n A 1 1000 CYS 1000 1000 1000 CYS CYS A . n A 1 1001 HIS 1001 1001 1001 HIS HIS A . n A 1 1002 LEU 1002 1002 1002 LEU LEU A . n A 1 1003 LEU 1003 1003 1003 LEU LEU A . n A 1 1004 PRO 1004 1004 1004 PRO PRO A . n A 1 1005 ASN 1005 1005 1005 ASN ASN A . n A 1 1006 VAL 1006 1006 1006 VAL VAL A . n A 1 1007 ALA 1007 1007 1007 ALA ALA A . n A 1 1008 ARG 1008 1008 1008 ARG ARG A . n A 1 1009 CYS 1009 1009 1009 CYS CYS A . n A 1 1010 GLU 1010 1010 1010 GLU GLU A . n A 1 1011 ARG 1011 1011 1011 ARG ARG A . n A 1 1012 THR 1012 1012 1012 THR THR A . n A 1 1013 THR 1013 1013 1013 THR THR A . n A 1 1014 LEU 1014 1014 1014 LEU LEU A . n A 1 1015 THR 1015 1015 1015 THR THR A . n A 1 1016 PHE 1016 1016 1016 PHE PHE A . n A 1 1017 LEU 1017 1017 1017 LEU LEU A . n A 1 1018 GLN 1018 1018 1018 GLN GLN A . n A 1 1019 ASN 1019 1019 1019 ASN ASN A . n A 1 1020 LEU 1020 1020 1020 LEU LEU A . n A 1 1021 GLU 1021 1021 1021 GLU GLU A . n A 1 1022 HIS 1022 1022 1022 HIS HIS A . n A 1 1023 LEU 1023 1023 1023 LEU LEU A . n A 1 1024 ASP 1024 1024 1024 ASP ASP A . n A 1 1025 GLY 1025 1025 1025 GLY GLY A . n A 1 1026 MET 1026 1026 1026 MET MET A . n A 1 1027 VAL 1027 1027 1027 VAL VAL A . n A 1 1028 ALA 1028 1028 1028 ALA ALA A . n A 1 1029 PRO 1029 1029 1029 PRO PRO A . n A 1 1030 GLU 1030 1030 1030 GLU GLU A . n A 1 1031 VAL 1031 1031 1031 VAL VAL A . n A 1 1032 CYS 1032 1032 1032 CYS CYS A . n A 1 1033 PRO 1033 1033 1033 PRO PRO A . n A 1 1034 MET 1034 1034 1034 MET MET A . n A 1 1035 GLU 1035 1035 1035 GLU GLU A . n A 1 1036 THR 1036 1036 1036 THR THR A . n A 1 1037 ALA 1037 1037 1037 ALA ALA A . n A 1 1038 ALA 1038 1038 1038 ALA ALA A . n A 1 1039 TYR 1039 1039 1039 TYR TYR A . n A 1 1040 VAL 1040 1040 1040 VAL VAL A . n A 1 1041 SER 1041 1041 1041 SER SER A . n A 1 1042 SER 1042 1042 1042 SER SER A . n A 1 1043 HIS 1043 1043 1043 HIS HIS A . n A 1 1044 SER 1044 1044 1044 SER SER A . n A 1 1045 SER 1045 1045 ? ? ? A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 1802 1802 NAG NAG A . C 3 PO4 1 1803 1803 PO4 PO4 A . D 4 ZN 1 1805 1805 ZN ZN A . E 5 GB1 1 1804 1804 GB1 GB1 A . F 6 MPD 1 1801 1801 MPD MPD A . G 7 HOH 1 1806 1 HOH HOH A . G 7 HOH 2 1807 2 HOH HOH A . G 7 HOH 3 1808 3 HOH HOH A . G 7 HOH 4 1809 4 HOH HOH A . G 7 HOH 5 1810 5 HOH HOH A . G 7 HOH 6 1811 6 HOH HOH A . G 7 HOH 7 1812 7 HOH HOH A . G 7 HOH 8 1813 8 HOH HOH A . G 7 HOH 9 1814 9 HOH HOH A . G 7 HOH 10 1815 10 HOH HOH A . G 7 HOH 11 1816 11 HOH HOH A . G 7 HOH 12 1817 12 HOH HOH A . G 7 HOH 13 1818 13 HOH HOH A . G 7 HOH 14 1819 14 HOH HOH A . G 7 HOH 15 1820 15 HOH HOH A . G 7 HOH 16 1821 16 HOH HOH A . G 7 HOH 17 1822 17 HOH HOH A . G 7 HOH 18 1823 18 HOH HOH A . G 7 HOH 19 1824 19 HOH HOH A . G 7 HOH 20 1825 20 HOH HOH A . G 7 HOH 21 1826 21 HOH HOH A . G 7 HOH 22 1827 22 HOH HOH A . G 7 HOH 23 1828 23 HOH HOH A . G 7 HOH 24 1829 24 HOH HOH A . G 7 HOH 25 1830 25 HOH HOH A . G 7 HOH 26 1831 26 HOH HOH A . G 7 HOH 27 1832 27 HOH HOH A . G 7 HOH 28 1833 28 HOH HOH A . G 7 HOH 29 1834 29 HOH HOH A . G 7 HOH 30 1835 30 HOH HOH A . G 7 HOH 31 1836 31 HOH HOH A . G 7 HOH 32 1837 32 HOH HOH A . G 7 HOH 33 1838 33 HOH HOH A . G 7 HOH 34 1839 34 HOH HOH A . G 7 HOH 35 1840 35 HOH HOH A . G 7 HOH 36 1841 36 HOH HOH A . G 7 HOH 37 1842 37 HOH HOH A . G 7 HOH 38 1843 38 HOH HOH A . G 7 HOH 39 1844 39 HOH HOH A . G 7 HOH 40 1845 40 HOH HOH A . G 7 HOH 41 1846 41 HOH HOH A . G 7 HOH 42 1847 42 HOH HOH A . G 7 HOH 43 1848 43 HOH HOH A . G 7 HOH 44 1849 44 HOH HOH A . G 7 HOH 45 1850 45 HOH HOH A . G 7 HOH 46 1851 46 HOH HOH A . G 7 HOH 47 1852 47 HOH HOH A . G 7 HOH 48 1853 48 HOH HOH A . G 7 HOH 49 1854 49 HOH HOH A . G 7 HOH 50 1855 50 HOH HOH A . G 7 HOH 51 1856 51 HOH HOH A . G 7 HOH 52 1857 52 HOH HOH A . G 7 HOH 53 1858 53 HOH HOH A . G 7 HOH 54 1859 54 HOH HOH A . G 7 HOH 55 1860 55 HOH HOH A . G 7 HOH 56 1861 56 HOH HOH A . G 7 HOH 57 1862 57 HOH HOH A . G 7 HOH 58 1863 58 HOH HOH A . G 7 HOH 59 1864 59 HOH HOH A . G 7 HOH 60 1865 60 HOH HOH A . G 7 HOH 61 1866 61 HOH HOH A . G 7 HOH 62 1867 62 HOH HOH A . G 7 HOH 63 1868 63 HOH HOH A . G 7 HOH 64 1869 64 HOH HOH A . G 7 HOH 65 1870 65 HOH HOH A . G 7 HOH 66 1871 66 HOH HOH A . G 7 HOH 67 1872 67 HOH HOH A . G 7 HOH 68 1873 68 HOH HOH A . G 7 HOH 69 1874 69 HOH HOH A . G 7 HOH 70 1875 70 HOH HOH A . G 7 HOH 71 1876 71 HOH HOH A . G 7 HOH 72 1877 72 HOH HOH A . G 7 HOH 73 1878 73 HOH HOH A . G 7 HOH 74 1879 74 HOH HOH A . G 7 HOH 75 1880 75 HOH HOH A . G 7 HOH 76 1881 76 HOH HOH A . G 7 HOH 77 1882 77 HOH HOH A . G 7 HOH 78 1883 78 HOH HOH A . G 7 HOH 79 1884 79 HOH HOH A . G 7 HOH 80 1885 80 HOH HOH A . G 7 HOH 81 1886 81 HOH HOH A . G 7 HOH 82 1887 82 HOH HOH A . G 7 HOH 83 1888 83 HOH HOH A . G 7 HOH 84 1889 84 HOH HOH A . G 7 HOH 85 1890 85 HOH HOH A . G 7 HOH 86 1891 86 HOH HOH A . G 7 HOH 87 1892 87 HOH HOH A . G 7 HOH 88 1893 88 HOH HOH A . G 7 HOH 89 1894 89 HOH HOH A . G 7 HOH 90 1895 90 HOH HOH A . G 7 HOH 91 1896 91 HOH HOH A . G 7 HOH 92 1897 92 HOH HOH A . G 7 HOH 93 1898 93 HOH HOH A . G 7 HOH 94 1899 94 HOH HOH A . G 7 HOH 95 1900 95 HOH HOH A . G 7 HOH 96 1901 96 HOH HOH A . G 7 HOH 97 1902 97 HOH HOH A . G 7 HOH 98 1903 98 HOH HOH A . G 7 HOH 99 1904 99 HOH HOH A . G 7 HOH 100 1905 100 HOH HOH A . G 7 HOH 101 1906 101 HOH HOH A . G 7 HOH 102 1907 102 HOH HOH A . G 7 HOH 103 1908 103 HOH HOH A . G 7 HOH 104 1909 104 HOH HOH A . G 7 HOH 105 1910 105 HOH HOH A . G 7 HOH 106 1911 106 HOH HOH A . G 7 HOH 107 1912 107 HOH HOH A . G 7 HOH 108 1913 108 HOH HOH A . G 7 HOH 109 1914 109 HOH HOH A . G 7 HOH 110 1915 110 HOH HOH A . G 7 HOH 111 1916 111 HOH HOH A . G 7 HOH 112 1917 112 HOH HOH A . G 7 HOH 113 1918 113 HOH HOH A . G 7 HOH 114 1919 114 HOH HOH A . G 7 HOH 115 1920 115 HOH HOH A . G 7 HOH 116 1921 116 HOH HOH A . G 7 HOH 117 1922 117 HOH HOH A . G 7 HOH 118 1923 118 HOH HOH A . G 7 HOH 119 1924 119 HOH HOH A . G 7 HOH 120 1925 120 HOH HOH A . G 7 HOH 121 1926 121 HOH HOH A . G 7 HOH 122 1927 122 HOH HOH A . G 7 HOH 123 1928 123 HOH HOH A . G 7 HOH 124 1929 124 HOH HOH A . G 7 HOH 125 1930 125 HOH HOH A . G 7 HOH 126 1931 126 HOH HOH A . G 7 HOH 127 1932 127 HOH HOH A . G 7 HOH 128 1933 128 HOH HOH A . G 7 HOH 129 1934 129 HOH HOH A . G 7 HOH 130 1935 130 HOH HOH A . G 7 HOH 131 1936 131 HOH HOH A . G 7 HOH 132 1937 132 HOH HOH A . G 7 HOH 133 1938 133 HOH HOH A . G 7 HOH 134 1939 134 HOH HOH A . G 7 HOH 135 1940 135 HOH HOH A . G 7 HOH 136 1941 136 HOH HOH A . G 7 HOH 137 1942 137 HOH HOH A . G 7 HOH 138 1943 138 HOH HOH A . G 7 HOH 139 1944 139 HOH HOH A . G 7 HOH 140 1945 140 HOH HOH A . G 7 HOH 141 1946 141 HOH HOH A . G 7 HOH 142 1947 142 HOH HOH A . G 7 HOH 143 1948 143 HOH HOH A . G 7 HOH 144 1949 144 HOH HOH A . G 7 HOH 145 1950 145 HOH HOH A . G 7 HOH 146 1951 146 HOH HOH A . G 7 HOH 147 1952 147 HOH HOH A . G 7 HOH 148 1953 148 HOH HOH A . G 7 HOH 149 1954 149 HOH HOH A . G 7 HOH 150 1955 150 HOH HOH A . G 7 HOH 151 1956 151 HOH HOH A . G 7 HOH 152 1957 152 HOH HOH A . G 7 HOH 153 1958 153 HOH HOH A . G 7 HOH 154 1959 154 HOH HOH A . G 7 HOH 155 1960 155 HOH HOH A . G 7 HOH 156 1961 156 HOH HOH A . G 7 HOH 157 1962 157 HOH HOH A . G 7 HOH 158 1963 158 HOH HOH A . G 7 HOH 159 1964 159 HOH HOH A . G 7 HOH 160 1965 160 HOH HOH A . G 7 HOH 161 1966 161 HOH HOH A . G 7 HOH 162 1967 162 HOH HOH A . G 7 HOH 163 1968 163 HOH HOH A . G 7 HOH 164 1969 164 HOH HOH A . G 7 HOH 165 1970 165 HOH HOH A . G 7 HOH 166 1971 166 HOH HOH A . G 7 HOH 167 1972 167 HOH HOH A . G 7 HOH 168 1973 168 HOH HOH A . G 7 HOH 169 1974 169 HOH HOH A . G 7 HOH 170 1975 170 HOH HOH A . G 7 HOH 171 1976 171 HOH HOH A . G 7 HOH 172 1977 172 HOH HOH A . G 7 HOH 173 1978 173 HOH HOH A . G 7 HOH 174 1979 174 HOH HOH A . G 7 HOH 175 1980 175 HOH HOH A . G 7 HOH 176 1981 176 HOH HOH A . G 7 HOH 177 1982 177 HOH HOH A . G 7 HOH 178 1983 178 HOH HOH A . G 7 HOH 179 1984 179 HOH HOH A . G 7 HOH 180 1985 180 HOH HOH A . G 7 HOH 181 1986 181 HOH HOH A . G 7 HOH 182 1987 182 HOH HOH A . G 7 HOH 183 1988 183 HOH HOH A . G 7 HOH 184 1989 184 HOH HOH A . G 7 HOH 185 1990 185 HOH HOH A . G 7 HOH 186 1991 186 HOH HOH A . G 7 HOH 187 1992 187 HOH HOH A . G 7 HOH 188 1993 188 HOH HOH A . G 7 HOH 189 1994 189 HOH HOH A . G 7 HOH 190 1995 190 HOH HOH A . G 7 HOH 191 1996 191 HOH HOH A . G 7 HOH 192 1997 192 HOH HOH A . G 7 HOH 193 1998 193 HOH HOH A . G 7 HOH 194 1999 194 HOH HOH A . G 7 HOH 195 2000 195 HOH HOH A . G 7 HOH 196 2001 196 HOH HOH A . G 7 HOH 197 2002 197 HOH HOH A . G 7 HOH 198 2003 198 HOH HOH A . G 7 HOH 199 2004 199 HOH HOH A . G 7 HOH 200 2005 200 HOH HOH A . G 7 HOH 201 2006 201 HOH HOH A . G 7 HOH 202 2007 202 HOH HOH A . G 7 HOH 203 2008 203 HOH HOH A . G 7 HOH 204 2009 204 HOH HOH A . G 7 HOH 205 2010 205 HOH HOH A . G 7 HOH 206 2011 206 HOH HOH A . G 7 HOH 207 2012 207 HOH HOH A . G 7 HOH 208 2013 208 HOH HOH A . G 7 HOH 209 2014 209 HOH HOH A . G 7 HOH 210 2015 210 HOH HOH A . G 7 HOH 211 2016 211 HOH HOH A . G 7 HOH 212 2017 212 HOH HOH A . G 7 HOH 213 2018 213 HOH HOH A . G 7 HOH 214 2019 214 HOH HOH A . G 7 HOH 215 2020 215 HOH HOH A . G 7 HOH 216 2021 216 HOH HOH A . G 7 HOH 217 2022 217 HOH HOH A . G 7 HOH 218 2023 218 HOH HOH A . G 7 HOH 219 2024 219 HOH HOH A . G 7 HOH 220 2025 220 HOH HOH A . G 7 HOH 221 2026 221 HOH HOH A . G 7 HOH 222 2027 222 HOH HOH A . G 7 HOH 223 2028 223 HOH HOH A . G 7 HOH 224 2029 224 HOH HOH A . G 7 HOH 225 2030 225 HOH HOH A . G 7 HOH 226 2031 226 HOH HOH A . G 7 HOH 227 2032 227 HOH HOH A . G 7 HOH 228 2033 228 HOH HOH A . G 7 HOH 229 2034 229 HOH HOH A . G 7 HOH 230 2035 230 HOH HOH A . G 7 HOH 231 2036 231 HOH HOH A . G 7 HOH 232 2037 232 HOH HOH A . G 7 HOH 233 2038 233 HOH HOH A . G 7 HOH 234 2039 234 HOH HOH A . G 7 HOH 235 2040 235 HOH HOH A . G 7 HOH 236 2041 236 HOH HOH A . G 7 HOH 237 2042 237 HOH HOH A . G 7 HOH 238 2043 238 HOH HOH A . G 7 HOH 239 2044 239 HOH HOH A . G 7 HOH 240 2045 240 HOH HOH A . G 7 HOH 241 2046 241 HOH HOH A . G 7 HOH 242 2047 242 HOH HOH A . G 7 HOH 243 2048 243 HOH HOH A . G 7 HOH 244 2049 244 HOH HOH A . G 7 HOH 245 2050 245 HOH HOH A . G 7 HOH 246 2051 246 HOH HOH A . G 7 HOH 247 2052 247 HOH HOH A . G 7 HOH 248 2053 248 HOH HOH A . G 7 HOH 249 2054 249 HOH HOH A . G 7 HOH 250 2055 250 HOH HOH A . G 7 HOH 251 2056 251 HOH HOH A . G 7 HOH 252 2057 252 HOH HOH A . G 7 HOH 253 2058 253 HOH HOH A . G 7 HOH 254 2059 254 HOH HOH A . G 7 HOH 255 2060 255 HOH HOH A . G 7 HOH 256 2061 256 HOH HOH A . G 7 HOH 257 2062 257 HOH HOH A . G 7 HOH 258 2063 258 HOH HOH A . G 7 HOH 259 2064 259 HOH HOH A . G 7 HOH 260 2065 260 HOH HOH A . G 7 HOH 261 2066 261 HOH HOH A . G 7 HOH 262 2067 262 HOH HOH A . G 7 HOH 263 2068 263 HOH HOH A . G 7 HOH 264 2069 264 HOH HOH A . G 7 HOH 265 2070 265 HOH HOH A . G 7 HOH 266 2071 266 HOH HOH A . G 7 HOH 267 2072 267 HOH HOH A . G 7 HOH 268 2073 268 HOH HOH A . G 7 HOH 269 2074 269 HOH HOH A . G 7 HOH 270 2075 270 HOH HOH A . G 7 HOH 271 2076 271 HOH HOH A . G 7 HOH 272 2077 272 HOH HOH A . G 7 HOH 273 2078 273 HOH HOH A . G 7 HOH 274 2079 274 HOH HOH A . G 7 HOH 275 2080 275 HOH HOH A . G 7 HOH 276 2081 276 HOH HOH A . G 7 HOH 277 2082 277 HOH HOH A . G 7 HOH 278 2083 278 HOH HOH A . G 7 HOH 279 2084 279 HOH HOH A . G 7 HOH 280 2085 280 HOH HOH A . G 7 HOH 281 2086 281 HOH HOH A . G 7 HOH 282 2087 282 HOH HOH A . G 7 HOH 283 2088 283 HOH HOH A . G 7 HOH 284 2089 284 HOH HOH A . G 7 HOH 285 2090 285 HOH HOH A . G 7 HOH 286 2091 286 HOH HOH A . G 7 HOH 287 2092 287 HOH HOH A . G 7 HOH 288 2093 288 HOH HOH A . G 7 HOH 289 2094 289 HOH HOH A . G 7 HOH 290 2095 290 HOH HOH A . G 7 HOH 291 2096 291 HOH HOH A . G 7 HOH 292 2097 292 HOH HOH A . G 7 HOH 293 2098 293 HOH HOH A . G 7 HOH 294 2099 294 HOH HOH A . G 7 HOH 295 2100 295 HOH HOH A . G 7 HOH 296 2101 296 HOH HOH A . G 7 HOH 297 2102 297 HOH HOH A . G 7 HOH 298 2103 298 HOH HOH A . G 7 HOH 299 2104 299 HOH HOH A . G 7 HOH 300 2105 300 HOH HOH A . G 7 HOH 301 2106 301 HOH HOH A . G 7 HOH 302 2107 302 HOH HOH A . G 7 HOH 303 2108 303 HOH HOH A . G 7 HOH 304 2109 304 HOH HOH A . G 7 HOH 305 2110 305 HOH HOH A . G 7 HOH 306 2111 306 HOH HOH A . G 7 HOH 307 2112 307 HOH HOH A . G 7 HOH 308 2113 308 HOH HOH A . G 7 HOH 309 2114 309 HOH HOH A . G 7 HOH 310 2115 310 HOH HOH A . G 7 HOH 311 2116 311 HOH HOH A . G 7 HOH 312 2117 312 HOH HOH A . G 7 HOH 313 2118 313 HOH HOH A . G 7 HOH 314 2119 314 HOH HOH A . G 7 HOH 315 2120 315 HOH HOH A . G 7 HOH 316 2121 316 HOH HOH A . G 7 HOH 317 2122 317 HOH HOH A . G 7 HOH 318 2123 318 HOH HOH A . G 7 HOH 319 2124 319 HOH HOH A . G 7 HOH 320 2125 320 HOH HOH A . G 7 HOH 321 2126 321 HOH HOH A . G 7 HOH 322 2127 322 HOH HOH A . G 7 HOH 323 2128 323 HOH HOH A . G 7 HOH 324 2129 324 HOH HOH A . G 7 HOH 325 2130 325 HOH HOH A . G 7 HOH 326 2131 326 HOH HOH A . G 7 HOH 327 2132 327 HOH HOH A . G 7 HOH 328 2133 328 HOH HOH A . G 7 HOH 329 2134 329 HOH HOH A . G 7 HOH 330 2135 330 HOH HOH A . G 7 HOH 331 2136 331 HOH HOH A . G 7 HOH 332 2137 332 HOH HOH A . G 7 HOH 333 2138 333 HOH HOH A . G 7 HOH 334 2139 334 HOH HOH A . G 7 HOH 335 2140 335 HOH HOH A . G 7 HOH 336 2141 336 HOH HOH A . G 7 HOH 337 2142 337 HOH HOH A . G 7 HOH 338 2143 338 HOH HOH A . G 7 HOH 339 2144 339 HOH HOH A . G 7 HOH 340 2145 340 HOH HOH A . G 7 HOH 341 2146 341 HOH HOH A . G 7 HOH 342 2147 342 HOH HOH A . G 7 HOH 343 2148 343 HOH HOH A . G 7 HOH 344 2149 344 HOH HOH A . G 7 HOH 345 2150 345 HOH HOH A . G 7 HOH 346 2151 346 HOH HOH A . G 7 HOH 347 2152 347 HOH HOH A . G 7 HOH 348 2153 348 HOH HOH A . G 7 HOH 349 2154 349 HOH HOH A . G 7 HOH 350 2155 350 HOH HOH A . G 7 HOH 351 2156 351 HOH HOH A . G 7 HOH 352 2157 352 HOH HOH A . G 7 HOH 353 2158 353 HOH HOH A . G 7 HOH 354 2159 354 HOH HOH A . G 7 HOH 355 2160 355 HOH HOH A . G 7 HOH 356 2161 356 HOH HOH A . G 7 HOH 357 2162 357 HOH HOH A . G 7 HOH 358 2163 358 HOH HOH A . G 7 HOH 359 2164 359 HOH HOH A . G 7 HOH 360 2165 360 HOH HOH A . G 7 HOH 361 2166 361 HOH HOH A . G 7 HOH 362 2167 362 HOH HOH A . G 7 HOH 363 2168 363 HOH HOH A . G 7 HOH 364 2169 364 HOH HOH A . G 7 HOH 365 2170 365 HOH HOH A . G 7 HOH 366 2171 366 HOH HOH A . G 7 HOH 367 2172 367 HOH HOH A . G 7 HOH 368 2173 368 HOH HOH A . G 7 HOH 369 2174 369 HOH HOH A . G 7 HOH 370 2175 370 HOH HOH A . G 7 HOH 371 2176 371 HOH HOH A . G 7 HOH 372 2177 372 HOH HOH A . G 7 HOH 373 2178 373 HOH HOH A . G 7 HOH 374 2179 374 HOH HOH A . G 7 HOH 375 2180 375 HOH HOH A . G 7 HOH 376 2181 376 HOH HOH A . G 7 HOH 377 2182 377 HOH HOH A . G 7 HOH 378 2183 378 HOH HOH A . G 7 HOH 379 2184 379 HOH HOH A . G 7 HOH 380 2185 380 HOH HOH A . G 7 HOH 381 2186 381 HOH HOH A . G 7 HOH 382 2187 382 HOH HOH A . G 7 HOH 383 2188 383 HOH HOH A . G 7 HOH 384 2189 384 HOH HOH A . G 7 HOH 385 2190 385 HOH HOH A . G 7 HOH 386 2191 386 HOH HOH A . G 7 HOH 387 2192 387 HOH HOH A . G 7 HOH 388 2193 388 HOH HOH A . G 7 HOH 389 2194 389 HOH HOH A . G 7 HOH 390 2195 390 HOH HOH A . G 7 HOH 391 2196 391 HOH HOH A . G 7 HOH 392 2197 392 HOH HOH A . G 7 HOH 393 2198 393 HOH HOH A . G 7 HOH 394 2199 394 HOH HOH A . G 7 HOH 395 2200 395 HOH HOH A . G 7 HOH 396 2201 396 HOH HOH A . G 7 HOH 397 2202 397 HOH HOH A . G 7 HOH 398 2203 398 HOH HOH A . G 7 HOH 399 2204 399 HOH HOH A . G 7 HOH 400 2205 400 HOH HOH A . G 7 HOH 401 2206 401 HOH HOH A . G 7 HOH 402 2207 402 HOH HOH A . G 7 HOH 403 2208 403 HOH HOH A . G 7 HOH 404 2209 404 HOH HOH A . G 7 HOH 405 2210 405 HOH HOH A . G 7 HOH 406 2211 406 HOH HOH A . G 7 HOH 407 2212 407 HOH HOH A . G 7 HOH 408 2213 408 HOH HOH A . G 7 HOH 409 2214 409 HOH HOH A . G 7 HOH 410 2215 410 HOH HOH A . G 7 HOH 411 2216 411 HOH HOH A . G 7 HOH 412 2217 412 HOH HOH A . G 7 HOH 413 2218 413 HOH HOH A . G 7 HOH 414 2219 414 HOH HOH A . G 7 HOH 415 2220 415 HOH HOH A . G 7 HOH 416 2221 416 HOH HOH A . G 7 HOH 417 2222 417 HOH HOH A . G 7 HOH 418 2223 418 HOH HOH A . G 7 HOH 419 2224 419 HOH HOH A . G 7 HOH 420 2225 420 HOH HOH A . G 7 HOH 421 2226 421 HOH HOH A . G 7 HOH 422 2227 422 HOH HOH A . G 7 HOH 423 2228 423 HOH HOH A . G 7 HOH 424 2229 424 HOH HOH A . G 7 HOH 425 2230 425 HOH HOH A . G 7 HOH 426 2231 426 HOH HOH A . G 7 HOH 427 2232 427 HOH HOH A . G 7 HOH 428 2233 428 HOH HOH A . G 7 HOH 429 2234 429 HOH HOH A . G 7 HOH 430 2235 430 HOH HOH A . G 7 HOH 431 2236 431 HOH HOH A . G 7 HOH 432 2237 432 HOH HOH A . G 7 HOH 433 2238 433 HOH HOH A . G 7 HOH 434 2239 434 HOH HOH A . G 7 HOH 435 2240 435 HOH HOH A . G 7 HOH 436 2241 436 HOH HOH A . G 7 HOH 437 2242 437 HOH HOH A . G 7 HOH 438 2243 438 HOH HOH A . G 7 HOH 439 2244 439 HOH HOH A . G 7 HOH 440 2245 440 HOH HOH A . G 7 HOH 441 2246 441 HOH HOH A . G 7 HOH 442 2247 442 HOH HOH A . G 7 HOH 443 2248 443 HOH HOH A . G 7 HOH 444 2249 444 HOH HOH A . G 7 HOH 445 2250 445 HOH HOH A . G 7 HOH 446 2251 446 HOH HOH A . G 7 HOH 447 2252 447 HOH HOH A . G 7 HOH 448 2253 448 HOH HOH A . G 7 HOH 449 2254 449 HOH HOH A . G 7 HOH 450 2255 450 HOH HOH A . G 7 HOH 451 2256 451 HOH HOH A . G 7 HOH 452 2257 452 HOH HOH A . G 7 HOH 453 2258 453 HOH HOH A . G 7 HOH 454 2259 454 HOH HOH A . G 7 HOH 455 2260 455 HOH HOH A . G 7 HOH 456 2261 456 HOH HOH A . G 7 HOH 457 2262 457 HOH HOH A . G 7 HOH 458 2263 458 HOH HOH A . G 7 HOH 459 2264 459 HOH HOH A . G 7 HOH 460 2265 460 HOH HOH A . G 7 HOH 461 2266 461 HOH HOH A . G 7 HOH 462 2267 462 HOH HOH A . G 7 HOH 463 2268 463 HOH HOH A . G 7 HOH 464 2269 464 HOH HOH A . G 7 HOH 465 2270 465 HOH HOH A . G 7 HOH 466 2271 466 HOH HOH A . G 7 HOH 467 2272 467 HOH HOH A . G 7 HOH 468 2273 468 HOH HOH A . G 7 HOH 469 2274 469 HOH HOH A . G 7 HOH 470 2275 470 HOH HOH A . G 7 HOH 471 2276 471 HOH HOH A . G 7 HOH 472 2277 472 HOH HOH A . G 7 HOH 473 2278 473 HOH HOH A . G 7 HOH 474 2279 474 HOH HOH A . G 7 HOH 475 2280 475 HOH HOH A . G 7 HOH 476 2281 476 HOH HOH A . G 7 HOH 477 2282 477 HOH HOH A . G 7 HOH 478 2283 478 HOH HOH A . G 7 HOH 479 2284 479 HOH HOH A . G 7 HOH 480 2285 480 HOH HOH A . G 7 HOH 481 2286 481 HOH HOH A . G 7 HOH 482 2287 482 HOH HOH A . G 7 HOH 483 2288 483 HOH HOH A . G 7 HOH 484 2289 484 HOH HOH A . G 7 HOH 485 2290 485 HOH HOH A . G 7 HOH 486 2291 486 HOH HOH A . G 7 HOH 487 2292 487 HOH HOH A . G 7 HOH 488 2293 488 HOH HOH A . G 7 HOH 489 2294 489 HOH HOH A . G 7 HOH 490 2295 490 HOH HOH A . G 7 HOH 491 2296 491 HOH HOH A . G 7 HOH 492 2297 492 HOH HOH A . G 7 HOH 493 2298 493 HOH HOH A . G 7 HOH 494 2299 494 HOH HOH A . G 7 HOH 495 2300 495 HOH HOH A . G 7 HOH 496 2301 496 HOH HOH A . G 7 HOH 497 2302 497 HOH HOH A . G 7 HOH 498 2303 498 HOH HOH A . G 7 HOH 499 2304 499 HOH HOH A . G 7 HOH 500 2305 500 HOH HOH A . G 7 HOH 501 2306 501 HOH HOH A . G 7 HOH 502 2307 502 HOH HOH A . G 7 HOH 503 2308 503 HOH HOH A . G 7 HOH 504 2309 504 HOH HOH A . G 7 HOH 505 2310 505 HOH HOH A . G 7 HOH 506 2311 506 HOH HOH A . G 7 HOH 507 2312 507 HOH HOH A . G 7 HOH 508 2313 508 HOH HOH A . G 7 HOH 509 2314 509 HOH HOH A . G 7 HOH 510 2315 510 HOH HOH A . G 7 HOH 511 2316 511 HOH HOH A . G 7 HOH 512 2317 512 HOH HOH A . G 7 HOH 513 2318 513 HOH HOH A . G 7 HOH 514 2319 514 HOH HOH A . G 7 HOH 515 2320 515 HOH HOH A . G 7 HOH 516 2321 516 HOH HOH A . G 7 HOH 517 2322 517 HOH HOH A . G 7 HOH 518 2323 518 HOH HOH A . G 7 HOH 519 2324 519 HOH HOH A . G 7 HOH 520 2325 520 HOH HOH A . G 7 HOH 521 2326 521 HOH HOH A . G 7 HOH 522 2327 522 HOH HOH A . G 7 HOH 523 2328 523 HOH HOH A . G 7 HOH 524 2329 524 HOH HOH A . G 7 HOH 525 2330 525 HOH HOH A . G 7 HOH 526 2331 526 HOH HOH A . G 7 HOH 527 2332 527 HOH HOH A . G 7 HOH 528 2333 528 HOH HOH A . G 7 HOH 529 2334 529 HOH HOH A . G 7 HOH 530 2335 530 HOH HOH A . G 7 HOH 531 2336 531 HOH HOH A . G 7 HOH 532 2337 532 HOH HOH A . G 7 HOH 533 2338 533 HOH HOH A . G 7 HOH 534 2339 534 HOH HOH A . G 7 HOH 535 2340 535 HOH HOH A . G 7 HOH 536 2341 536 HOH HOH A . G 7 HOH 537 2342 537 HOH HOH A . G 7 HOH 538 2343 538 HOH HOH A . G 7 HOH 539 2344 539 HOH HOH A . G 7 HOH 540 2345 540 HOH HOH A . G 7 HOH 541 2346 541 HOH HOH A . G 7 HOH 542 2347 542 HOH HOH A . G 7 HOH 543 2348 543 HOH HOH A . G 7 HOH 544 2349 544 HOH HOH A . G 7 HOH 545 2350 545 HOH HOH A . G 7 HOH 546 2351 546 HOH HOH A . G 7 HOH 547 2352 547 HOH HOH A . G 7 HOH 548 2353 548 HOH HOH A . G 7 HOH 549 2354 549 HOH HOH A . G 7 HOH 550 2355 550 HOH HOH A . G 7 HOH 551 2356 551 HOH HOH A . G 7 HOH 552 2357 552 HOH HOH A . G 7 HOH 553 2358 553 HOH HOH A . G 7 HOH 554 2359 554 HOH HOH A . G 7 HOH 555 2360 555 HOH HOH A . G 7 HOH 556 2361 556 HOH HOH A . G 7 HOH 557 2362 557 HOH HOH A . G 7 HOH 558 2363 558 HOH HOH A . G 7 HOH 559 2364 559 HOH HOH A . G 7 HOH 560 2365 560 HOH HOH A . G 7 HOH 561 2366 561 HOH HOH A . G 7 HOH 562 2367 562 HOH HOH A . G 7 HOH 563 2368 563 HOH HOH A . G 7 HOH 564 2369 564 HOH HOH A . G 7 HOH 565 2370 565 HOH HOH A . G 7 HOH 566 2371 566 HOH HOH A . G 7 HOH 567 2372 567 HOH HOH A . G 7 HOH 568 2373 568 HOH HOH A . G 7 HOH 569 2374 569 HOH HOH A . G 7 HOH 570 2375 570 HOH HOH A . G 7 HOH 571 2376 571 HOH HOH A . G 7 HOH 572 2377 572 HOH HOH A . G 7 HOH 573 2378 573 HOH HOH A . G 7 HOH 574 2379 574 HOH HOH A . G 7 HOH 575 2380 575 HOH HOH A . G 7 HOH 576 2381 576 HOH HOH A . G 7 HOH 577 2382 577 HOH HOH A . G 7 HOH 578 2383 578 HOH HOH A . G 7 HOH 579 2384 579 HOH HOH A . G 7 HOH 580 2385 580 HOH HOH A . G 7 HOH 581 2386 581 HOH HOH A . G 7 HOH 582 2387 582 HOH HOH A . G 7 HOH 583 2388 583 HOH HOH A . G 7 HOH 584 2389 584 HOH HOH A . G 7 HOH 585 2390 585 HOH HOH A . G 7 HOH 586 2391 586 HOH HOH A . G 7 HOH 587 2392 587 HOH HOH A . G 7 HOH 588 2393 588 HOH HOH A . G 7 HOH 589 2394 589 HOH HOH A . G 7 HOH 590 2395 590 HOH HOH A . G 7 HOH 591 2396 591 HOH HOH A . G 7 HOH 592 2397 592 HOH HOH A . G 7 HOH 593 2398 593 HOH HOH A . G 7 HOH 594 2399 594 HOH HOH A . G 7 HOH 595 2400 595 HOH HOH A . G 7 HOH 596 2401 596 HOH HOH A . G 7 HOH 597 2402 597 HOH HOH A . G 7 HOH 598 2403 598 HOH HOH A . G 7 HOH 599 2404 599 HOH HOH A . G 7 HOH 600 2405 600 HOH HOH A . G 7 HOH 601 2406 601 HOH HOH A . G 7 HOH 602 2407 602 HOH HOH A . G 7 HOH 603 2408 603 HOH HOH A . G 7 HOH 604 2409 604 HOH HOH A . G 7 HOH 605 2410 605 HOH HOH A . G 7 HOH 606 2411 606 HOH HOH A . G 7 HOH 607 2412 607 HOH HOH A . G 7 HOH 608 2413 608 HOH HOH A . G 7 HOH 609 2414 609 HOH HOH A . G 7 HOH 610 2415 610 HOH HOH A . G 7 HOH 611 2416 611 HOH HOH A . G 7 HOH 612 2417 612 HOH HOH A . G 7 HOH 613 2418 613 HOH HOH A . G 7 HOH 614 2419 614 HOH HOH A . G 7 HOH 615 2420 615 HOH HOH A . G 7 HOH 616 2421 616 HOH HOH A . G 7 HOH 617 2422 617 HOH HOH A . G 7 HOH 618 2423 618 HOH HOH A . G 7 HOH 619 2424 619 HOH HOH A . G 7 HOH 620 2425 620 HOH HOH A . G 7 HOH 621 2426 621 HOH HOH A . G 7 HOH 622 2427 622 HOH HOH A . G 7 HOH 623 2428 623 HOH HOH A . G 7 HOH 624 2429 624 HOH HOH A . G 7 HOH 625 2430 625 HOH HOH A . G 7 HOH 626 2431 626 HOH HOH A . G 7 HOH 627 2432 627 HOH HOH A . G 7 HOH 628 2433 628 HOH HOH A . G 7 HOH 629 2434 629 HOH HOH A . G 7 HOH 630 2435 630 HOH HOH A . G 7 HOH 631 2436 631 HOH HOH A . G 7 HOH 632 2437 632 HOH HOH A . G 7 HOH 633 2438 633 HOH HOH A . G 7 HOH 634 2439 634 HOH HOH A . G 7 HOH 635 2440 635 HOH HOH A . G 7 HOH 636 2441 636 HOH HOH A . G 7 HOH 637 2442 637 HOH HOH A . G 7 HOH 638 2443 638 HOH HOH A . G 7 HOH 639 2444 639 HOH HOH A . G 7 HOH 640 2445 640 HOH HOH A . G 7 HOH 641 2446 641 HOH HOH A . G 7 HOH 642 2447 642 HOH HOH A . G 7 HOH 643 2448 643 HOH HOH A . G 7 HOH 644 2449 644 HOH HOH A . G 7 HOH 645 2450 645 HOH HOH A . G 7 HOH 646 2451 646 HOH HOH A . G 7 HOH 647 2452 647 HOH HOH A . G 7 HOH 648 2453 648 HOH HOH A . G 7 HOH 649 2454 649 HOH HOH A . G 7 HOH 650 2455 650 HOH HOH A . G 7 HOH 651 2456 651 HOH HOH A . G 7 HOH 652 2457 652 HOH HOH A . G 7 HOH 653 2458 653 HOH HOH A . G 7 HOH 654 2459 654 HOH HOH A . G 7 HOH 655 2460 655 HOH HOH A . G 7 HOH 656 2461 656 HOH HOH A . G 7 HOH 657 2462 657 HOH HOH A . G 7 HOH 658 2463 658 HOH HOH A . G 7 HOH 659 2464 659 HOH HOH A . G 7 HOH 660 2465 660 HOH HOH A . G 7 HOH 661 2466 661 HOH HOH A . G 7 HOH 662 2467 662 HOH HOH A . G 7 HOH 663 2468 663 HOH HOH A . G 7 HOH 664 2469 664 HOH HOH A . G 7 HOH 665 2470 665 HOH HOH A . G 7 HOH 666 2471 666 HOH HOH A . G 7 HOH 667 2472 667 HOH HOH A . G 7 HOH 668 2473 668 HOH HOH A . G 7 HOH 669 2474 669 HOH HOH A . G 7 HOH 670 2475 670 HOH HOH A . G 7 HOH 671 2476 671 HOH HOH A . G 7 HOH 672 2477 672 HOH HOH A . G 7 HOH 673 2478 673 HOH HOH A . G 7 HOH 674 2479 674 HOH HOH A . G 7 HOH 675 2480 675 HOH HOH A . G 7 HOH 676 2481 676 HOH HOH A . G 7 HOH 677 2482 677 HOH HOH A . G 7 HOH 678 2483 678 HOH HOH A . G 7 HOH 679 2484 679 HOH HOH A . G 7 HOH 680 2485 680 HOH HOH A . G 7 HOH 681 2486 681 HOH HOH A . G 7 HOH 682 2487 682 HOH HOH A . G 7 HOH 683 2488 683 HOH HOH A . G 7 HOH 684 2489 684 HOH HOH A . G 7 HOH 685 2490 685 HOH HOH A . G 7 HOH 686 2491 686 HOH HOH A . G 7 HOH 687 2492 687 HOH HOH A . G 7 HOH 688 2493 688 HOH HOH A . G 7 HOH 689 2494 689 HOH HOH A . G 7 HOH 690 2495 690 HOH HOH A . G 7 HOH 691 2496 691 HOH HOH A . G 7 HOH 692 2497 692 HOH HOH A . G 7 HOH 693 2498 693 HOH HOH A . G 7 HOH 694 2499 694 HOH HOH A . G 7 HOH 695 2500 695 HOH HOH A . G 7 HOH 696 2501 696 HOH HOH A . G 7 HOH 697 2502 697 HOH HOH A . G 7 HOH 698 2503 698 HOH HOH A . G 7 HOH 699 2504 699 HOH HOH A . G 7 HOH 700 2505 700 HOH HOH A . G 7 HOH 701 2506 701 HOH HOH A . G 7 HOH 702 2507 702 HOH HOH A . G 7 HOH 703 2508 703 HOH HOH A . G 7 HOH 704 2509 704 HOH HOH A . G 7 HOH 705 2510 705 HOH HOH A . G 7 HOH 706 2511 706 HOH HOH A . G 7 HOH 707 2512 707 HOH HOH A . G 7 HOH 708 2513 708 HOH HOH A . G 7 HOH 709 2514 709 HOH HOH A . G 7 HOH 710 2515 710 HOH HOH A . G 7 HOH 711 2516 711 HOH HOH A . G 7 HOH 712 2517 712 HOH HOH A . G 7 HOH 713 2518 713 HOH HOH A . G 7 HOH 714 2519 714 HOH HOH A . G 7 HOH 715 2520 715 HOH HOH A . G 7 HOH 716 2521 716 HOH HOH A . G 7 HOH 717 2522 717 HOH HOH A . G 7 HOH 718 2523 718 HOH HOH A . G 7 HOH 719 2524 719 HOH HOH A . G 7 HOH 720 2525 720 HOH HOH A . G 7 HOH 721 2526 721 HOH HOH A . G 7 HOH 722 2527 722 HOH HOH A . G 7 HOH 723 2528 723 HOH HOH A . G 7 HOH 724 2529 724 HOH HOH A . G 7 HOH 725 2530 725 HOH HOH A . G 7 HOH 726 2531 726 HOH HOH A . G 7 HOH 727 2532 727 HOH HOH A . G 7 HOH 728 2533 728 HOH HOH A . G 7 HOH 729 2534 729 HOH HOH A . G 7 HOH 730 2535 730 HOH HOH A . G 7 HOH 731 2536 731 HOH HOH A . G 7 HOH 732 2537 732 HOH HOH A . G 7 HOH 733 2538 733 HOH HOH A . G 7 HOH 734 2539 734 HOH HOH A . G 7 HOH 735 2540 735 HOH HOH A . G 7 HOH 736 2541 736 HOH HOH A . G 7 HOH 737 2542 737 HOH HOH A . G 7 HOH 738 2543 738 HOH HOH A . G 7 HOH 739 2544 739 HOH HOH A . G 7 HOH 740 2545 740 HOH HOH A . G 7 HOH 741 2546 741 HOH HOH A . G 7 HOH 742 2547 742 HOH HOH A . G 7 HOH 743 2548 743 HOH HOH A . G 7 HOH 744 2549 744 HOH HOH A . G 7 HOH 745 2550 745 HOH HOH A . G 7 HOH 746 2551 746 HOH HOH A . G 7 HOH 747 2552 747 HOH HOH A . G 7 HOH 748 2553 748 HOH HOH A . G 7 HOH 749 2554 749 HOH HOH A . G 7 HOH 750 2555 750 HOH HOH A . G 7 HOH 751 2556 751 HOH HOH A . G 7 HOH 752 2557 752 HOH HOH A . G 7 HOH 753 2558 753 HOH HOH A . G 7 HOH 754 2559 754 HOH HOH A . G 7 HOH 755 2560 755 HOH HOH A . G 7 HOH 756 2561 756 HOH HOH A . G 7 HOH 757 2562 757 HOH HOH A . G 7 HOH 758 2563 758 HOH HOH A . G 7 HOH 759 2564 759 HOH HOH A . G 7 HOH 760 2565 760 HOH HOH A . G 7 HOH 761 2566 761 HOH HOH A . G 7 HOH 762 2567 762 HOH HOH A . G 7 HOH 763 2568 763 HOH HOH A . G 7 HOH 764 2569 764 HOH HOH A . G 7 HOH 765 2570 765 HOH HOH A . G 7 HOH 766 2571 766 HOH HOH A . G 7 HOH 767 2572 767 HOH HOH A . G 7 HOH 768 2573 768 HOH HOH A . G 7 HOH 769 2574 769 HOH HOH A . G 7 HOH 770 2575 770 HOH HOH A . G 7 HOH 771 2576 771 HOH HOH A . G 7 HOH 772 2577 772 HOH HOH A . G 7 HOH 773 2578 773 HOH HOH A . G 7 HOH 774 2579 774 HOH HOH A . G 7 HOH 775 2580 775 HOH HOH A . G 7 HOH 776 2581 776 HOH HOH A . G 7 HOH 777 2582 777 HOH HOH A . G 7 HOH 778 2583 778 HOH HOH A . G 7 HOH 779 2584 779 HOH HOH A . G 7 HOH 780 2585 780 HOH HOH A . G 7 HOH 781 2586 781 HOH HOH A . G 7 HOH 782 2587 782 HOH HOH A . G 7 HOH 783 2588 783 HOH HOH A . G 7 HOH 784 2589 784 HOH HOH A . G 7 HOH 785 2590 785 HOH HOH A . G 7 HOH 786 2591 786 HOH HOH A . G 7 HOH 787 2592 787 HOH HOH A . G 7 HOH 788 2593 788 HOH HOH A . G 7 HOH 789 2594 789 HOH HOH A . G 7 HOH 790 2595 790 HOH HOH A . G 7 HOH 791 2596 791 HOH HOH A . G 7 HOH 792 2597 792 HOH HOH A . G 7 HOH 793 2598 793 HOH HOH A . G 7 HOH 794 2599 794 HOH HOH A . G 7 HOH 795 2600 795 HOH HOH A . G 7 HOH 796 2601 796 HOH HOH A . G 7 HOH 797 2602 797 HOH HOH A . G 7 HOH 798 2603 798 HOH HOH A . G 7 HOH 799 2604 799 HOH HOH A . G 7 HOH 800 2605 800 HOH HOH A . G 7 HOH 801 2606 801 HOH HOH A . G 7 HOH 802 2607 802 HOH HOH A . G 7 HOH 803 2608 803 HOH HOH A . G 7 HOH 804 2609 804 HOH HOH A . G 7 HOH 805 2610 805 HOH HOH A . G 7 HOH 806 2611 806 HOH HOH A . G 7 HOH 807 2612 807 HOH HOH A . G 7 HOH 808 2613 808 HOH HOH A . G 7 HOH 809 2614 809 HOH HOH A . G 7 HOH 810 2615 810 HOH HOH A . G 7 HOH 811 2616 811 HOH HOH A . G 7 HOH 812 2617 812 HOH HOH A . G 7 HOH 813 2618 813 HOH HOH A . G 7 HOH 814 2619 814 HOH HOH A . G 7 HOH 815 2620 815 HOH HOH A . G 7 HOH 816 2621 816 HOH HOH A . G 7 HOH 817 2622 817 HOH HOH A . G 7 HOH 818 2623 818 HOH HOH A . G 7 HOH 819 2624 819 HOH HOH A . G 7 HOH 820 2625 820 HOH HOH A . G 7 HOH 821 2626 821 HOH HOH A . G 7 HOH 822 2627 822 HOH HOH A . G 7 HOH 823 2628 823 HOH HOH A . G 7 HOH 824 2629 824 HOH HOH A . G 7 HOH 825 2630 825 HOH HOH A . G 7 HOH 826 2631 826 HOH HOH A . G 7 HOH 827 2632 827 HOH HOH A . G 7 HOH 828 2633 828 HOH HOH A . G 7 HOH 829 2634 829 HOH HOH A . G 7 HOH 830 2635 830 HOH HOH A . G 7 HOH 831 2636 831 HOH HOH A . G 7 HOH 832 2637 832 HOH HOH A . G 7 HOH 833 2638 833 HOH HOH A . G 7 HOH 834 2639 834 HOH HOH A . G 7 HOH 835 2640 835 HOH HOH A . G 7 HOH 836 2641 836 HOH HOH A . G 7 HOH 837 2642 837 HOH HOH A . G 7 HOH 838 2643 838 HOH HOH A . G 7 HOH 839 2644 839 HOH HOH A . G 7 HOH 840 2645 840 HOH HOH A . G 7 HOH 841 2646 841 HOH HOH A . G 7 HOH 842 2647 842 HOH HOH A . G 7 HOH 843 2648 843 HOH HOH A . G 7 HOH 844 2649 844 HOH HOH A . G 7 HOH 845 2650 845 HOH HOH A . G 7 HOH 846 2651 846 HOH HOH A . G 7 HOH 847 2652 847 HOH HOH A . G 7 HOH 848 2653 848 HOH HOH A . G 7 HOH 849 2654 849 HOH HOH A . G 7 HOH 850 2655 850 HOH HOH A . G 7 HOH 851 2656 851 HOH HOH A . G 7 HOH 852 2657 852 HOH HOH A . G 7 HOH 853 2658 853 HOH HOH A . G 7 HOH 854 2659 854 HOH HOH A . G 7 HOH 855 2660 855 HOH HOH A . G 7 HOH 856 2661 856 HOH HOH A . G 7 HOH 857 2662 857 HOH HOH A . G 7 HOH 858 2663 858 HOH HOH A . G 7 HOH 859 2664 859 HOH HOH A . G 7 HOH 860 2665 860 HOH HOH A . G 7 HOH 861 2666 861 HOH HOH A . G 7 HOH 862 2667 862 HOH HOH A . G 7 HOH 863 2668 863 HOH HOH A . G 7 HOH 864 2669 864 HOH HOH A . G 7 HOH 865 2670 865 HOH HOH A . G 7 HOH 866 2671 866 HOH HOH A . G 7 HOH 867 2672 867 HOH HOH A . G 7 HOH 868 2673 868 HOH HOH A . G 7 HOH 869 2674 869 HOH HOH A . G 7 HOH 870 2675 870 HOH HOH A . G 7 HOH 871 2676 871 HOH HOH A . G 7 HOH 872 2677 872 HOH HOH A . G 7 HOH 873 2678 873 HOH HOH A . G 7 HOH 874 2679 874 HOH HOH A . G 7 HOH 875 2680 875 HOH HOH A . G 7 HOH 876 2681 876 HOH HOH A . G 7 HOH 877 2682 877 HOH HOH A . G 7 HOH 878 2683 878 HOH HOH A . G 7 HOH 879 2684 879 HOH HOH A . G 7 HOH 880 2685 880 HOH HOH A . G 7 HOH 881 2686 881 HOH HOH A . G 7 HOH 882 2687 882 HOH HOH A . G 7 HOH 883 2688 883 HOH HOH A . G 7 HOH 884 2689 884 HOH HOH A . G 7 HOH 885 2690 885 HOH HOH A . G 7 HOH 886 2691 886 HOH HOH A . G 7 HOH 887 2692 887 HOH HOH A . G 7 HOH 888 2693 888 HOH HOH A . G 7 HOH 889 2694 889 HOH HOH A . G 7 HOH 890 2695 890 HOH HOH A . G 7 HOH 891 2696 891 HOH HOH A . G 7 HOH 892 2697 892 HOH HOH A . G 7 HOH 893 2698 893 HOH HOH A . G 7 HOH 894 2699 894 HOH HOH A . G 7 HOH 895 2700 895 HOH HOH A . G 7 HOH 896 2701 896 HOH HOH A . G 7 HOH 897 2702 897 HOH HOH A . G 7 HOH 898 2703 898 HOH HOH A . G 7 HOH 899 2704 899 HOH HOH A . G 7 HOH 900 2705 900 HOH HOH A . G 7 HOH 901 2706 901 HOH HOH A . G 7 HOH 902 2707 902 HOH HOH A . G 7 HOH 903 2708 903 HOH HOH A . G 7 HOH 904 2709 904 HOH HOH A . G 7 HOH 905 2710 905 HOH HOH A . G 7 HOH 906 2711 906 HOH HOH A . G 7 HOH 907 2712 907 HOH HOH A . G 7 HOH 908 2713 908 HOH HOH A . G 7 HOH 909 2714 909 HOH HOH A . G 7 HOH 910 2715 910 HOH HOH A . G 7 HOH 911 2716 911 HOH HOH A . G 7 HOH 912 2717 912 HOH HOH A . G 7 HOH 913 2718 913 HOH HOH A . G 7 HOH 914 2719 914 HOH HOH A . G 7 HOH 915 2720 915 HOH HOH A . G 7 HOH 916 2721 916 HOH HOH A . G 7 HOH 917 2722 917 HOH HOH A . G 7 HOH 918 2723 918 HOH HOH A . G 7 HOH 919 2724 919 HOH HOH A . G 7 HOH 920 2725 920 HOH HOH A . G 7 HOH 921 2726 921 HOH HOH A . G 7 HOH 922 2727 922 HOH HOH A . G 7 HOH 923 2728 923 HOH HOH A . G 7 HOH 924 2729 924 HOH HOH A . G 7 HOH 925 2730 925 HOH HOH A . G 7 HOH 926 2731 926 HOH HOH A . G 7 HOH 927 2732 927 HOH HOH A . G 7 HOH 928 2733 928 HOH HOH A . G 7 HOH 929 2734 929 HOH HOH A . G 7 HOH 930 2735 930 HOH HOH A . G 7 HOH 931 2736 931 HOH HOH A . G 7 HOH 932 2737 932 HOH HOH A . G 7 HOH 933 2738 933 HOH HOH A . G 7 HOH 934 2739 934 HOH HOH A . G 7 HOH 935 2740 935 HOH HOH A . G 7 HOH 936 2741 936 HOH HOH A . G 7 HOH 937 2742 937 HOH HOH A . G 7 HOH 938 2743 938 HOH HOH A . G 7 HOH 939 2744 939 HOH HOH A . G 7 HOH 940 2745 940 HOH HOH A . G 7 HOH 941 2746 941 HOH HOH A . G 7 HOH 942 2747 942 HOH HOH A . G 7 HOH 943 2748 943 HOH HOH A . G 7 HOH 944 2749 944 HOH HOH A . G 7 HOH 945 2750 945 HOH HOH A . G 7 HOH 946 2751 946 HOH HOH A . G 7 HOH 947 2752 947 HOH HOH A . G 7 HOH 948 2753 948 HOH HOH A . G 7 HOH 949 2754 949 HOH HOH A . G 7 HOH 950 2755 950 HOH HOH A . G 7 HOH 951 2756 951 HOH HOH A . G 7 HOH 952 2757 952 HOH HOH A . G 7 HOH 953 2758 953 HOH HOH A . G 7 HOH 954 2759 954 HOH HOH A . G 7 HOH 955 2760 955 HOH HOH A . G 7 HOH 956 2761 956 HOH HOH A . G 7 HOH 957 2762 957 HOH HOH A . G 7 HOH 958 2763 958 HOH HOH A . G 7 HOH 959 2764 959 HOH HOH A . G 7 HOH 960 2765 960 HOH HOH A . G 7 HOH 961 2766 961 HOH HOH A . G 7 HOH 962 2767 962 HOH HOH A . G 7 HOH 963 2768 963 HOH HOH A . G 7 HOH 964 2769 964 HOH HOH A . G 7 HOH 965 2770 965 HOH HOH A . G 7 HOH 966 2771 966 HOH HOH A . G 7 HOH 967 2772 967 HOH HOH A . G 7 HOH 968 2773 968 HOH HOH A . G 7 HOH 969 2774 969 HOH HOH A . G 7 HOH 970 2775 970 HOH HOH A . G 7 HOH 971 2776 971 HOH HOH A . G 7 HOH 972 2777 972 HOH HOH A . G 7 HOH 973 2778 973 HOH HOH A . G 7 HOH 974 2779 974 HOH HOH A . G 7 HOH 975 2780 975 HOH HOH A . G 7 HOH 976 2781 976 HOH HOH A . G 7 HOH 977 2782 977 HOH HOH A . G 7 HOH 978 2783 978 HOH HOH A . G 7 HOH 979 2784 979 HOH HOH A . G 7 HOH 980 2785 980 HOH HOH A . G 7 HOH 981 2786 981 HOH HOH A . G 7 HOH 982 2787 982 HOH HOH A . G 7 HOH 983 2788 983 HOH HOH A . G 7 HOH 984 2789 984 HOH HOH A . G 7 HOH 985 2790 985 HOH HOH A . G 7 HOH 986 2791 986 HOH HOH A . G 7 HOH 987 2792 987 HOH HOH A . G 7 HOH 988 2793 988 HOH HOH A . G 7 HOH 989 2794 989 HOH HOH A . G 7 HOH 990 2795 990 HOH HOH A . G 7 HOH 991 2796 991 HOH HOH A . G 7 HOH 992 2797 992 HOH HOH A . G 7 HOH 993 2798 993 HOH HOH A . G 7 HOH 994 2799 994 HOH HOH A . G 7 HOH 995 2800 995 HOH HOH A . G 7 HOH 996 2801 996 HOH HOH A . G 7 HOH 997 2802 997 HOH HOH A . G 7 HOH 998 2803 998 HOH HOH A . G 7 HOH 999 2804 999 HOH HOH A . G 7 HOH 1000 2805 1000 HOH HOH A . G 7 HOH 1001 2806 1001 HOH HOH A . G 7 HOH 1002 2807 1002 HOH HOH A . G 7 HOH 1003 2808 1003 HOH HOH A . G 7 HOH 1004 2809 1004 HOH HOH A . G 7 HOH 1005 2810 1005 HOH HOH A . G 7 HOH 1006 2811 1006 HOH HOH A . G 7 HOH 1007 2812 1007 HOH HOH A . G 7 HOH 1008 2813 1008 HOH HOH A . G 7 HOH 1009 2814 1009 HOH HOH A . G 7 HOH 1010 2815 1010 HOH HOH A . G 7 HOH 1011 2816 1011 HOH HOH A . G 7 HOH 1012 2817 1012 HOH HOH A . G 7 HOH 1013 2818 1013 HOH HOH A . G 7 HOH 1014 2819 1014 HOH HOH A . G 7 HOH 1015 2820 1015 HOH HOH A . G 7 HOH 1016 2821 1016 HOH HOH A . G 7 HOH 1017 2822 1017 HOH HOH A . G 7 HOH 1018 2823 1018 HOH HOH A . G 7 HOH 1019 2824 1019 HOH HOH A . G 7 HOH 1020 2825 1020 HOH HOH A . G 7 HOH 1021 2826 1021 HOH HOH A . G 7 HOH 1022 2827 1022 HOH HOH A . G 7 HOH 1023 2828 1023 HOH HOH A . G 7 HOH 1024 2829 1024 HOH HOH A . G 7 HOH 1025 2830 1025 HOH HOH A . G 7 HOH 1026 2831 1026 HOH HOH A . G 7 HOH 1027 2832 1027 HOH HOH A . G 7 HOH 1028 2833 1028 HOH HOH A . G 7 HOH 1029 2834 1029 HOH HOH A . G 7 HOH 1030 2835 1030 HOH HOH A . G 7 HOH 1031 2836 1031 HOH HOH A . G 7 HOH 1032 2837 1032 HOH HOH A . G 7 HOH 1033 2838 1033 HOH HOH A . G 7 HOH 1034 2839 1034 HOH HOH A . G 7 HOH 1035 2840 1035 HOH HOH A . G 7 HOH 1036 2841 1036 HOH HOH A . G 7 HOH 1037 2842 1037 HOH HOH A . G 7 HOH 1038 2843 1038 HOH HOH A . G 7 HOH 1039 2844 1039 HOH HOH A . G 7 HOH 1040 2845 1040 HOH HOH A . G 7 HOH 1041 2846 1041 HOH HOH A . G 7 HOH 1042 2847 1042 HOH HOH A . G 7 HOH 1043 2848 1043 HOH HOH A . G 7 HOH 1044 2849 1044 HOH HOH A . G 7 HOH 1045 2850 1045 HOH HOH A . G 7 HOH 1046 2851 1046 HOH HOH A . G 7 HOH 1047 2852 1047 HOH HOH A . G 7 HOH 1048 2853 1048 HOH HOH A . G 7 HOH 1049 2854 1049 HOH HOH A . G 7 HOH 1050 2855 1050 HOH HOH A . G 7 HOH 1051 2856 1051 HOH HOH A . G 7 HOH 1052 2857 1052 HOH HOH A . G 7 HOH 1053 2858 1053 HOH HOH A . G 7 HOH 1054 2859 1054 HOH HOH A . G 7 HOH 1055 2860 1055 HOH HOH A . G 7 HOH 1056 2861 1056 HOH HOH A . G 7 HOH 1057 2862 1057 HOH HOH A . G 7 HOH 1058 2863 1058 HOH HOH A . G 7 HOH 1059 2864 1059 HOH HOH A . G 7 HOH 1060 2865 1060 HOH HOH A . G 7 HOH 1061 2866 1061 HOH HOH A . G 7 HOH 1062 2867 1062 HOH HOH A . G 7 HOH 1063 2868 1063 HOH HOH A . G 7 HOH 1064 2869 1064 HOH HOH A . G 7 HOH 1065 2870 1065 HOH HOH A . G 7 HOH 1066 2871 1066 HOH HOH A . G 7 HOH 1067 2872 1067 HOH HOH A . G 7 HOH 1068 2873 1068 HOH HOH A . G 7 HOH 1069 2874 1069 HOH HOH A . G 7 HOH 1070 2875 1070 HOH HOH A . G 7 HOH 1071 2876 1071 HOH HOH A . G 7 HOH 1072 2877 1072 HOH HOH A . G 7 HOH 1073 2878 1073 HOH HOH A . G 7 HOH 1074 2879 1074 HOH HOH A . G 7 HOH 1075 2880 1075 HOH HOH A . G 7 HOH 1076 2881 1076 HOH HOH A . G 7 HOH 1077 2882 1077 HOH HOH A . G 7 HOH 1078 2883 1078 HOH HOH A . G 7 HOH 1079 2884 1079 HOH HOH A . G 7 HOH 1080 2885 1080 HOH HOH A . G 7 HOH 1081 2886 1081 HOH HOH A . G 7 HOH 1082 2887 1082 HOH HOH A . G 7 HOH 1083 2888 1083 HOH HOH A . G 7 HOH 1084 2889 1084 HOH HOH A . G 7 HOH 1085 2890 1085 HOH HOH A . G 7 HOH 1086 2891 1086 HOH HOH A . G 7 HOH 1087 2892 1087 HOH HOH A . G 7 HOH 1088 2893 1088 HOH HOH A . G 7 HOH 1089 2894 1089 HOH HOH A . G 7 HOH 1090 2895 1090 HOH HOH A . G 7 HOH 1091 2896 1091 HOH HOH A . G 7 HOH 1092 2897 1092 HOH HOH A . G 7 HOH 1093 2898 1093 HOH HOH A . G 7 HOH 1094 2899 1094 HOH HOH A . G 7 HOH 1095 2900 1095 HOH HOH A . G 7 HOH 1096 2901 1096 HOH HOH A . G 7 HOH 1097 2902 1097 HOH HOH A . G 7 HOH 1098 2903 1098 HOH HOH A . G 7 HOH 1099 2904 1099 HOH HOH A . G 7 HOH 1100 2905 1100 HOH HOH A . G 7 HOH 1101 2906 1101 HOH HOH A . G 7 HOH 1102 2907 1102 HOH HOH A . G 7 HOH 1103 2908 1103 HOH HOH A . G 7 HOH 1104 2909 1104 HOH HOH A . G 7 HOH 1105 2910 1105 HOH HOH A . G 7 HOH 1106 2911 1106 HOH HOH A . G 7 HOH 1107 2912 1107 HOH HOH A . G 7 HOH 1108 2913 1108 HOH HOH A . G 7 HOH 1109 2914 1109 HOH HOH A . G 7 HOH 1110 2915 1110 HOH HOH A . G 7 HOH 1111 2916 1111 HOH HOH A . G 7 HOH 1112 2917 1112 HOH HOH A . G 7 HOH 1113 2918 1113 HOH HOH A . G 7 HOH 1114 2919 1114 HOH HOH A . G 7 HOH 1115 2920 1115 HOH HOH A . G 7 HOH 1116 2921 1116 HOH HOH A . G 7 HOH 1117 2922 1117 HOH HOH A . G 7 HOH 1118 2923 1118 HOH HOH A . G 7 HOH 1119 2924 1119 HOH HOH A . G 7 HOH 1120 2925 1120 HOH HOH A . G 7 HOH 1121 2926 1121 HOH HOH A . G 7 HOH 1122 2927 1122 HOH HOH A . G 7 HOH 1123 2928 1123 HOH HOH A . G 7 HOH 1124 2929 1124 HOH HOH A . G 7 HOH 1125 2930 1125 HOH HOH A . G 7 HOH 1126 2931 1126 HOH HOH A . G 7 HOH 1127 2932 1127 HOH HOH A . G 7 HOH 1128 2933 1128 HOH HOH A . G 7 HOH 1129 2934 1129 HOH HOH A . G 7 HOH 1130 2935 1130 HOH HOH A . G 7 HOH 1131 2936 1131 HOH HOH A . G 7 HOH 1132 2937 1132 HOH HOH A . G 7 HOH 1133 2938 1133 HOH HOH A . G 7 HOH 1134 2939 1134 HOH HOH A . G 7 HOH 1135 2940 1135 HOH HOH A . G 7 HOH 1136 2941 1136 HOH HOH A . G 7 HOH 1137 2942 1137 HOH HOH A . G 7 HOH 1138 2943 1138 HOH HOH A . G 7 HOH 1139 2944 1139 HOH HOH A . G 7 HOH 1140 2945 1140 HOH HOH A . G 7 HOH 1141 2946 1141 HOH HOH A . G 7 HOH 1142 2947 1142 HOH HOH A . G 7 HOH 1143 2948 1143 HOH HOH A . G 7 HOH 1144 2949 1144 HOH HOH A . G 7 HOH 1145 2950 1145 HOH HOH A . G 7 HOH 1146 2951 1146 HOH HOH A . G 7 HOH 1147 2952 1147 HOH HOH A . G 7 HOH 1148 2953 1148 HOH HOH A . G 7 HOH 1149 2954 1149 HOH HOH A . G 7 HOH 1150 2955 1150 HOH HOH A . G 7 HOH 1151 2956 1151 HOH HOH A . G 7 HOH 1152 2957 1152 HOH HOH A . G 7 HOH 1153 2958 1153 HOH HOH A . G 7 HOH 1154 2959 1154 HOH HOH A . G 7 HOH 1155 2960 1155 HOH HOH A . G 7 HOH 1156 2961 1156 HOH HOH A . G 7 HOH 1157 2962 1157 HOH HOH A . G 7 HOH 1158 2963 1158 HOH HOH A . G 7 HOH 1159 2964 1159 HOH HOH A . G 7 HOH 1160 2965 1160 HOH HOH A . G 7 HOH 1161 2966 1161 HOH HOH A . G 7 HOH 1162 2967 1162 HOH HOH A . G 7 HOH 1163 2968 1163 HOH HOH A . G 7 HOH 1164 2969 1164 HOH HOH A . G 7 HOH 1165 2970 1165 HOH HOH A . G 7 HOH 1166 2971 1166 HOH HOH A . G 7 HOH 1167 2972 1167 HOH HOH A . G 7 HOH 1168 2973 1168 HOH HOH A . G 7 HOH 1169 2974 1169 HOH HOH A . G 7 HOH 1170 2975 1170 HOH HOH A . G 7 HOH 1171 2976 1171 HOH HOH A . G 7 HOH 1172 2977 1172 HOH HOH A . # _pdbx_struct_mod_residue.id 1 _pdbx_struct_mod_residue.label_asym_id A _pdbx_struct_mod_residue.label_comp_id ASN _pdbx_struct_mod_residue.label_seq_id 194 _pdbx_struct_mod_residue.auth_asym_id A _pdbx_struct_mod_residue.auth_comp_id ASN _pdbx_struct_mod_residue.auth_seq_id 194 _pdbx_struct_mod_residue.PDB_ins_code ? _pdbx_struct_mod_residue.parent_comp_id ASN _pdbx_struct_mod_residue.details 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 91.7 ? 2 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 98.4 ? 3 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 168.6 ? 4 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 105.4 ? 5 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 91.9 ? 6 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 90.5 ? 7 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O3 ? E GB1 . ? A GB1 1804 ? 1_555 161.4 ? 8 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O3 ? E GB1 . ? A GB1 1804 ? 1_555 88.0 ? 9 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O3 ? E GB1 . ? A GB1 1804 ? 1_555 80.8 ? 10 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O3 ? E GB1 . ? A GB1 1804 ? 1_555 93.1 ? 11 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O4 ? E GB1 . ? A GB1 1804 ? 1_555 89.7 ? 12 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O4 ? E GB1 . ? A GB1 1804 ? 1_555 90.2 ? 13 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O4 ? E GB1 . ? A GB1 1804 ? 1_555 84.7 ? 14 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O4 ? E GB1 . ? A GB1 1804 ? 1_555 164.6 ? 15 O3 ? E GB1 . ? A GB1 1804 ? 1_555 ZN ? D ZN . ? A ZN 1805 ? 1_555 O4 ? E GB1 . ? A GB1 1804 ? 1_555 71.7 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2006-12-05 2 'Structure model' 1 1 2007-10-16 3 'Structure model' 1 2 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Non-polymer description' 3 3 'Structure model' 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal CNS refinement 1.1 ? 1 HKL-2000 'data reduction' . ? 2 SCALEPACK 'data scaling' . ? 3 CNS phasing . ? 4 # _pdbx_validate_close_contact.id 1 _pdbx_validate_close_contact.PDB_model_num 1 _pdbx_validate_close_contact.auth_atom_id_1 O _pdbx_validate_close_contact.auth_asym_id_1 A _pdbx_validate_close_contact.auth_comp_id_1 ASP _pdbx_validate_close_contact.auth_seq_id_1 33 _pdbx_validate_close_contact.PDB_ins_code_1 ? _pdbx_validate_close_contact.label_alt_id_1 ? _pdbx_validate_close_contact.auth_atom_id_2 O _pdbx_validate_close_contact.auth_asym_id_2 A _pdbx_validate_close_contact.auth_comp_id_2 HOH _pdbx_validate_close_contact.auth_seq_id_2 2749 _pdbx_validate_close_contact.PDB_ins_code_2 ? _pdbx_validate_close_contact.label_alt_id_2 ? _pdbx_validate_close_contact.dist 2.17 # loop_ _pdbx_validate_rmsd_bond.id _pdbx_validate_rmsd_bond.PDB_model_num _pdbx_validate_rmsd_bond.auth_atom_id_1 _pdbx_validate_rmsd_bond.auth_asym_id_1 _pdbx_validate_rmsd_bond.auth_comp_id_1 _pdbx_validate_rmsd_bond.auth_seq_id_1 _pdbx_validate_rmsd_bond.PDB_ins_code_1 _pdbx_validate_rmsd_bond.label_alt_id_1 _pdbx_validate_rmsd_bond.auth_atom_id_2 _pdbx_validate_rmsd_bond.auth_asym_id_2 _pdbx_validate_rmsd_bond.auth_comp_id_2 _pdbx_validate_rmsd_bond.auth_seq_id_2 _pdbx_validate_rmsd_bond.PDB_ins_code_2 _pdbx_validate_rmsd_bond.label_alt_id_2 _pdbx_validate_rmsd_bond.bond_value _pdbx_validate_rmsd_bond.bond_target_value _pdbx_validate_rmsd_bond.bond_deviation _pdbx_validate_rmsd_bond.bond_standard_deviation _pdbx_validate_rmsd_bond.linker_flag 1 1 CA A SER 597 ? ? CB A SER 597 ? B 1.675 1.525 0.150 0.015 N 2 1 CB A ARG 770 ? ? CG A ARG 770 ? B 1.312 1.521 -0.209 0.027 N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 N A SER 53 ? ? CA A SER 53 ? ? CB A SER 53 ? B 121.37 110.50 10.87 1.50 N 2 1 CB A ASN 155 ? B CA A ASN 155 ? ? C A ASN 155 ? B 124.09 110.40 13.69 2.00 N 3 1 CB A ASP 316 ? B CA A ASP 316 ? ? C A ASP 316 ? ? 97.07 110.40 -13.33 2.00 N 4 1 NE A ARG 565 ? ? CZ A ARG 565 ? ? NH2 A ARG 565 ? ? 116.96 120.30 -3.34 0.50 N 5 1 CB A ASP 839 ? ? CG A ASP 839 ? ? OD2 A ASP 839 ? ? 112.57 118.30 -5.73 0.90 N 6 1 NE A ARG 843 ? ? CZ A ARG 843 ? ? NH2 A ARG 843 ? ? 117.07 120.30 -3.23 0.50 N 7 1 NE A ARG 868 ? ? CZ A ARG 868 ? ? NH2 A ARG 868 ? ? 117.29 120.30 -3.01 0.50 N 8 1 NE A ARG 963 ? ? CZ A ARG 963 ? ? NH1 A ARG 963 ? ? 123.83 120.30 3.53 0.50 N 9 1 NE A ARG 963 ? ? CZ A ARG 963 ? ? NH2 A ARG 963 ? ? 116.64 120.30 -3.66 0.50 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 56 ? ? -101.09 79.28 2 1 TRP A 95 ? ? -171.58 -84.67 3 1 ASP A 106 ? ? -124.13 -57.78 4 1 ASP A 106 ? ? -134.21 -57.78 5 1 THR A 162 ? ? 66.51 -65.03 6 1 GLN A 227 ? ? -135.94 -44.64 7 1 ASP A 340 ? ? -171.30 -172.07 8 1 LYS A 345 ? ? -92.17 -71.74 9 1 SER A 411 ? ? 40.92 -122.13 10 1 SER A 411 ? ? 61.28 -134.88 11 1 ILE A 549 ? ? -144.67 -47.84 12 1 LEU A 550 ? ? -167.98 118.50 13 1 PRO A 562 ? ? -83.71 39.02 14 1 PHE A 577 ? ? -100.47 73.71 15 1 SER A 703 ? ? -48.20 163.92 16 1 ASN A 732 ? ? -97.18 57.30 17 1 SER A 762 ? ? 72.49 -1.69 18 1 ILE A 831 ? ? -116.91 78.02 19 1 SER A 833 ? ? -151.64 -14.02 20 1 ASP A 839 ? ? -127.56 -162.59 21 1 PRO A 990 ? ? -35.07 -74.96 22 1 GLU A 991 ? ? 58.53 95.49 23 1 GLU A 992 ? ? -125.01 -145.71 24 1 HIS A 993 ? ? 27.78 76.71 # loop_ _pdbx_validate_main_chain_plane.id _pdbx_validate_main_chain_plane.PDB_model_num _pdbx_validate_main_chain_plane.auth_comp_id _pdbx_validate_main_chain_plane.auth_asym_id _pdbx_validate_main_chain_plane.auth_seq_id _pdbx_validate_main_chain_plane.PDB_ins_code _pdbx_validate_main_chain_plane.label_alt_id _pdbx_validate_main_chain_plane.improper_torsion_angle 1 1 ASP A 316 ? B -14.59 2 1 GLN A 766 ? B -13.86 3 1 THR A 848 ? B -11.55 # _pdbx_validate_chiral.id 1 _pdbx_validate_chiral.PDB_model_num 1 _pdbx_validate_chiral.auth_atom_id C4 _pdbx_validate_chiral.label_alt_id ? _pdbx_validate_chiral.auth_asym_id A _pdbx_validate_chiral.auth_comp_id MPD _pdbx_validate_chiral.auth_seq_id 1801 _pdbx_validate_chiral.PDB_ins_code ? _pdbx_validate_chiral.details 'WRONG HAND' _pdbx_validate_chiral.omega . # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ARG 1 ? A ARG 1 2 1 Y 1 A SER 2 ? A SER 2 3 1 Y 1 A SER 3 ? A SER 3 4 1 Y 1 A HIS 4 ? A HIS 4 5 1 Y 1 A HIS 5 ? A HIS 5 6 1 Y 1 A HIS 6 ? A HIS 6 7 1 Y 1 A HIS 7 ? A HIS 7 8 1 Y 1 A HIS 8 ? A HIS 8 9 1 Y 1 A HIS 9 ? A HIS 9 10 1 Y 1 A GLY 10 ? A GLY 10 11 1 Y 1 A GLU 11 ? A GLU 11 12 1 Y 1 A PHE 12 ? A PHE 12 13 1 Y 1 A ASP 13 ? A ASP 13 14 1 Y 1 A ASP 14 ? A ASP 14 15 1 Y 1 A PRO 15 ? A PRO 15 16 1 Y 1 A ILE 16 ? A ILE 16 17 1 Y 1 A ARG 17 ? A ARG 17 18 1 Y 1 A PRO 18 ? A PRO 18 19 1 Y 1 A PRO 19 ? A PRO 19 20 1 Y 1 A LEU 20 ? A LEU 20 21 1 Y 1 A LYS 21 ? A LYS 21 22 1 Y 1 A VAL 22 ? A VAL 22 23 1 Y 1 A ALA 23 ? A ALA 23 24 1 Y 1 A ARG 24 ? A ARG 24 25 1 Y 1 A SER 25 ? A SER 25 26 1 Y 1 A PRO 26 ? A PRO 26 27 1 Y 1 A ARG 27 ? A ARG 27 28 1 Y 1 A PRO 28 ? A PRO 28 29 1 Y 1 A GLY 29 ? A GLY 29 30 1 Y 1 A GLN 30 ? A GLN 30 31 1 Y 1 A SER 1045 ? A SER 1045 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 'PHOSPHATE ION' PO4 4 'ZINC ION' ZN 5 '(2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL' GB1 6 '(4S)-2-METHYL-2,4-PENTANEDIOL' MPD 7 water HOH #