data_2DW2 # _entry.id 2DW2 # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.281 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 2DW2 RCSB RCSB025913 WWPDB D_1000025913 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 2DW0 'the same protein(Form 2-1 crystal)' unspecified PDB 2DW1 'the same protein(Form 2-2 crystal)' unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 2DW2 _pdbx_database_status.recvd_initial_deposition_date 2006-08-02 _pdbx_database_status.deposit_site PDBJ _pdbx_database_status.process_site PDBJ _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Takeda, S.' 1 'Igarashi, T.' 2 'Araki, S.' 3 # loop_ _citation.id _citation.title _citation.journal_abbrev _citation.journal_volume _citation.page_first _citation.page_last _citation.year _citation.journal_id_ASTM _citation.country _citation.journal_id_ISSN _citation.journal_id_CSD _citation.book_publisher _citation.pdbx_database_id_PubMed _citation.pdbx_database_id_DOI primary 'Crystal structures of catrocollastatin/VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/reprolysin family proteins' 'Febs Lett.' 581 2416 2422 2007 FEBLAL NE 0014-5793 0165 ? 17485084 10.1016/j.febslet.2007.04.057 1 ;Crystallization and preliminary X-ray crystallographic analysis of two vascular apoptosis-inducing proteins (VAPs) from Crotalus atrox venom. ; 'ACTA CRYSTALLOGR.,SECT.F' 62 688 691 2006 ? DK 1744-3091 ? ? 16820695 10.1107/S1744309106022548 2 ;Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold ; 'Embo J.' 25 2388 2396 2006 EMJODG UK 0261-4189 0897 ? 16688218 10.1038/sj.emboj.7601131 3 'cDNA cloning and some additional peptide characterization of a single-chain vascular apoptosis-inducing protein, VAP2' ENDOTHELIUM 14 89 96 2007 ? ? 1062-3329 0353 ? 17497365 10.1080/10623320701346882 4 'Two vascular apoptosis-inducing proteins from snake venom are members of the metalloprotease/disintegrin family' Eur.J.Biochem. 253 36 41 1998 EJBCAI IX 0014-2956 0262 ? 9578458 10.1046/j.1432-1327.1998.2530036.x # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Igarashi, T.' 1 primary 'Araki, S.' 2 primary 'Mori, H.' 3 primary 'Takeda, S.' 4 1 'Igarashi, T.' 5 1 'Oishi, Y.' 6 1 'Araki, S.' 7 1 'Mori, H.' 8 1 'Takeda, S.' 9 2 'Takeda, S.' 10 2 'Igarashi, T.' 11 2 'Mori, H.' 12 2 'Araki, S.' 13 3 'Masuda, S.' 14 3 'Maeda, H.' 15 3 'Miao, J.Y.' 16 3 'Hayashi, H.' 17 3 'Araki, S.' 18 4 'Masuda, S.' 19 4 'Hayashi, H.' 20 4 'Araki, S.' 21 # _cell.entry_id 2DW2 _cell.length_a 220.742 _cell.length_b 79.475 _cell.length_c 58.690 _cell.angle_alpha 90.00 _cell.angle_beta 91.73 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 2DW2 _symmetry.space_group_name_H-M 'C 1 2 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 5 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer nat Catrocollastatin 46912.762 2 ? ? 'residues 191-609' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 10 ? ? ? ? 3 non-polymer man BETA-D-MANNOSE 180.156 2 ? ? ? ? 4 non-polymer man ALPHA-D-MANNOSE 180.156 4 ? ? ? ? 5 non-polymer man ALPHA-L-FUCOSE 164.156 2 ? ? ? ? 6 non-polymer syn 'ZINC ION' 65.409 2 ? ? ? ? 7 non-polymer syn 'CALCIUM ION' 40.078 6 ? ? ? ? 8 water nat water 18.015 151 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'VAP2, vascular apoptosis-inducing protein-2, catrocollastatin/VAP2B' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;HQKYNPFRFVELVLVVDKAMVTKNNGDLDKIKTRMYEIVNTVNEIYRYMYIHVALVGLEIWSNEDKITVKPEAGYTLNAF GEWRKTDLLTRKKHDNAQLLTAIDLDRVIGLAYVGSMCHPKRSTGIIQDYSEINLVVAVIMAHEMGHNLGINHDSGYCSC GDYACIMRPEISPEPSTFFSNCSYFECWDFIMNHNPECILNEPLGTDIISPPVCGNELLEVGEECDCGTPENCQNECCDA ATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQC YDLFGADVYEAEDSCFERNQKGNYYGYCRKENGNKIPCAPEDVKCGRLYCKDNSPGQNNPCKMFYSNEDEHKGMVLPGTK CADGKVCSNGHCVDVATAY ; _entity_poly.pdbx_seq_one_letter_code_can ;HQKYNPFRFVELVLVVDKAMVTKNNGDLDKIKTRMYEIVNTVNEIYRYMYIHVALVGLEIWSNEDKITVKPEAGYTLNAF GEWRKTDLLTRKKHDNAQLLTAIDLDRVIGLAYVGSMCHPKRSTGIIQDYSEINLVVAVIMAHEMGHNLGINHDSGYCSC GDYACIMRPEISPEPSTFFSNCSYFECWDFIMNHNPECILNEPLGTDIISPPVCGNELLEVGEECDCGTPENCQNECCDA ATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQC YDLFGADVYEAEDSCFERNQKGNYYGYCRKENGNKIPCAPEDVKCGRLYCKDNSPGQNNPCKMFYSNEDEHKGMVLPGTK CADGKVCSNGHCVDVATAY ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 HIS n 1 2 GLN n 1 3 LYS n 1 4 TYR n 1 5 ASN n 1 6 PRO n 1 7 PHE n 1 8 ARG n 1 9 PHE n 1 10 VAL n 1 11 GLU n 1 12 LEU n 1 13 VAL n 1 14 LEU n 1 15 VAL n 1 16 VAL n 1 17 ASP n 1 18 LYS n 1 19 ALA n 1 20 MET n 1 21 VAL n 1 22 THR n 1 23 LYS n 1 24 ASN n 1 25 ASN n 1 26 GLY n 1 27 ASP n 1 28 LEU n 1 29 ASP n 1 30 LYS n 1 31 ILE n 1 32 LYS n 1 33 THR n 1 34 ARG n 1 35 MET n 1 36 TYR n 1 37 GLU n 1 38 ILE n 1 39 VAL n 1 40 ASN n 1 41 THR n 1 42 VAL n 1 43 ASN n 1 44 GLU n 1 45 ILE n 1 46 TYR n 1 47 ARG n 1 48 TYR n 1 49 MET n 1 50 TYR n 1 51 ILE n 1 52 HIS n 1 53 VAL n 1 54 ALA n 1 55 LEU n 1 56 VAL n 1 57 GLY n 1 58 LEU n 1 59 GLU n 1 60 ILE n 1 61 TRP n 1 62 SER n 1 63 ASN n 1 64 GLU n 1 65 ASP n 1 66 LYS n 1 67 ILE n 1 68 THR n 1 69 VAL n 1 70 LYS n 1 71 PRO n 1 72 GLU n 1 73 ALA n 1 74 GLY n 1 75 TYR n 1 76 THR n 1 77 LEU n 1 78 ASN n 1 79 ALA n 1 80 PHE n 1 81 GLY n 1 82 GLU n 1 83 TRP n 1 84 ARG n 1 85 LYS n 1 86 THR n 1 87 ASP n 1 88 LEU n 1 89 LEU n 1 90 THR n 1 91 ARG n 1 92 LYS n 1 93 LYS n 1 94 HIS n 1 95 ASP n 1 96 ASN n 1 97 ALA n 1 98 GLN n 1 99 LEU n 1 100 LEU n 1 101 THR n 1 102 ALA n 1 103 ILE n 1 104 ASP n 1 105 LEU n 1 106 ASP n 1 107 ARG n 1 108 VAL n 1 109 ILE n 1 110 GLY n 1 111 LEU n 1 112 ALA n 1 113 TYR n 1 114 VAL n 1 115 GLY n 1 116 SER n 1 117 MET n 1 118 CYS n 1 119 HIS n 1 120 PRO n 1 121 LYS n 1 122 ARG n 1 123 SER n 1 124 THR n 1 125 GLY n 1 126 ILE n 1 127 ILE n 1 128 GLN n 1 129 ASP n 1 130 TYR n 1 131 SER n 1 132 GLU n 1 133 ILE n 1 134 ASN n 1 135 LEU n 1 136 VAL n 1 137 VAL n 1 138 ALA n 1 139 VAL n 1 140 ILE n 1 141 MET n 1 142 ALA n 1 143 HIS n 1 144 GLU n 1 145 MET n 1 146 GLY n 1 147 HIS n 1 148 ASN n 1 149 LEU n 1 150 GLY n 1 151 ILE n 1 152 ASN n 1 153 HIS n 1 154 ASP n 1 155 SER n 1 156 GLY n 1 157 TYR n 1 158 CYS n 1 159 SER n 1 160 CYS n 1 161 GLY n 1 162 ASP n 1 163 TYR n 1 164 ALA n 1 165 CYS n 1 166 ILE n 1 167 MET n 1 168 ARG n 1 169 PRO n 1 170 GLU n 1 171 ILE n 1 172 SER n 1 173 PRO n 1 174 GLU n 1 175 PRO n 1 176 SER n 1 177 THR n 1 178 PHE n 1 179 PHE n 1 180 SER n 1 181 ASN n 1 182 CYS n 1 183 SER n 1 184 TYR n 1 185 PHE n 1 186 GLU n 1 187 CYS n 1 188 TRP n 1 189 ASP n 1 190 PHE n 1 191 ILE n 1 192 MET n 1 193 ASN n 1 194 HIS n 1 195 ASN n 1 196 PRO n 1 197 GLU n 1 198 CYS n 1 199 ILE n 1 200 LEU n 1 201 ASN n 1 202 GLU n 1 203 PRO n 1 204 LEU n 1 205 GLY n 1 206 THR n 1 207 ASP n 1 208 ILE n 1 209 ILE n 1 210 SER n 1 211 PRO n 1 212 PRO n 1 213 VAL n 1 214 CYS n 1 215 GLY n 1 216 ASN n 1 217 GLU n 1 218 LEU n 1 219 LEU n 1 220 GLU n 1 221 VAL n 1 222 GLY n 1 223 GLU n 1 224 GLU n 1 225 CYS n 1 226 ASP n 1 227 CYS n 1 228 GLY n 1 229 THR n 1 230 PRO n 1 231 GLU n 1 232 ASN n 1 233 CYS n 1 234 GLN n 1 235 ASN n 1 236 GLU n 1 237 CYS n 1 238 CYS n 1 239 ASP n 1 240 ALA n 1 241 ALA n 1 242 THR n 1 243 CYS n 1 244 LYS n 1 245 LEU n 1 246 LYS n 1 247 SER n 1 248 GLY n 1 249 SER n 1 250 GLN n 1 251 CYS n 1 252 GLY n 1 253 HIS n 1 254 GLY n 1 255 ASP n 1 256 CYS n 1 257 CYS n 1 258 GLU n 1 259 GLN n 1 260 CYS n 1 261 LYS n 1 262 PHE n 1 263 SER n 1 264 LYS n 1 265 SER n 1 266 GLY n 1 267 THR n 1 268 GLU n 1 269 CYS n 1 270 ARG n 1 271 ALA n 1 272 SER n 1 273 MET n 1 274 SER n 1 275 GLU n 1 276 CYS n 1 277 ASP n 1 278 PRO n 1 279 ALA n 1 280 GLU n 1 281 HIS n 1 282 CYS n 1 283 THR n 1 284 GLY n 1 285 GLN n 1 286 SER n 1 287 SER n 1 288 GLU n 1 289 CYS n 1 290 PRO n 1 291 ALA n 1 292 ASP n 1 293 VAL n 1 294 PHE n 1 295 HIS n 1 296 LYS n 1 297 ASN n 1 298 GLY n 1 299 GLN n 1 300 PRO n 1 301 CYS n 1 302 LEU n 1 303 ASP n 1 304 ASN n 1 305 TYR n 1 306 GLY n 1 307 TYR n 1 308 CYS n 1 309 TYR n 1 310 ASN n 1 311 GLY n 1 312 ASN n 1 313 CYS n 1 314 PRO n 1 315 ILE n 1 316 MET n 1 317 TYR n 1 318 HIS n 1 319 GLN n 1 320 CYS n 1 321 TYR n 1 322 ASP n 1 323 LEU n 1 324 PHE n 1 325 GLY n 1 326 ALA n 1 327 ASP n 1 328 VAL n 1 329 TYR n 1 330 GLU n 1 331 ALA n 1 332 GLU n 1 333 ASP n 1 334 SER n 1 335 CYS n 1 336 PHE n 1 337 GLU n 1 338 ARG n 1 339 ASN n 1 340 GLN n 1 341 LYS n 1 342 GLY n 1 343 ASN n 1 344 TYR n 1 345 TYR n 1 346 GLY n 1 347 TYR n 1 348 CYS n 1 349 ARG n 1 350 LYS n 1 351 GLU n 1 352 ASN n 1 353 GLY n 1 354 ASN n 1 355 LYS n 1 356 ILE n 1 357 PRO n 1 358 CYS n 1 359 ALA n 1 360 PRO n 1 361 GLU n 1 362 ASP n 1 363 VAL n 1 364 LYS n 1 365 CYS n 1 366 GLY n 1 367 ARG n 1 368 LEU n 1 369 TYR n 1 370 CYS n 1 371 LYS n 1 372 ASP n 1 373 ASN n 1 374 SER n 1 375 PRO n 1 376 GLY n 1 377 GLN n 1 378 ASN n 1 379 ASN n 1 380 PRO n 1 381 CYS n 1 382 LYS n 1 383 MET n 1 384 PHE n 1 385 TYR n 1 386 SER n 1 387 ASN n 1 388 GLU n 1 389 ASP n 1 390 GLU n 1 391 HIS n 1 392 LYS n 1 393 GLY n 1 394 MET n 1 395 VAL n 1 396 LEU n 1 397 PRO n 1 398 GLY n 1 399 THR n 1 400 LYS n 1 401 CYS n 1 402 ALA n 1 403 ASP n 1 404 GLY n 1 405 LYS n 1 406 VAL n 1 407 CYS n 1 408 SER n 1 409 ASN n 1 410 GLY n 1 411 HIS n 1 412 CYS n 1 413 VAL n 1 414 ASP n 1 415 VAL n 1 416 ALA n 1 417 THR n 1 418 ALA n 1 419 TYR n # _entity_src_nat.entity_id 1 _entity_src_nat.pdbx_src_id 1 _entity_src_nat.pdbx_alt_source_flag sample _entity_src_nat.pdbx_beg_seq_num ? _entity_src_nat.pdbx_end_seq_num ? _entity_src_nat.common_name 'western diamondback rattlesnake' _entity_src_nat.pdbx_organism_scientific 'Crotalus atrox' _entity_src_nat.pdbx_ncbi_taxonomy_id 8730 _entity_src_nat.genus Crotalus _entity_src_nat.species ? _entity_src_nat.strain ? _entity_src_nat.tissue ? _entity_src_nat.tissue_fraction ? _entity_src_nat.pdbx_secretion ? _entity_src_nat.pdbx_fragment ? _entity_src_nat.pdbx_variant ? _entity_src_nat.pdbx_cell_line ? _entity_src_nat.pdbx_atcc ? _entity_src_nat.pdbx_cellular_location ? _entity_src_nat.pdbx_organ ? _entity_src_nat.pdbx_organelle ? _entity_src_nat.pdbx_cell ? _entity_src_nat.pdbx_plasmid_name ? _entity_src_nat.pdbx_plasmid_details ? _entity_src_nat.details ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code Q90282_CROAT _struct_ref.pdbx_db_accession Q90282 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;HQKYNPFRFVELFLVVDKAMVTKNNGDLDKIKTRMYEIVNTVNEIYRYMYIHVALVGLEIWSNEDKITVKPEAGYTLNAF GEWRKTDLLTRKKHDNAQLLTAIDLDRVIGLAYVGSMCHPKRSTGIIQDYSEINLVVAVIMAHEMGHNLGINHDSGYCSC GDYACIMRPEISPEPSTFFSNCSYFECWDFIMNHNPECILNEPLGTDIISPPVCGNELLEVGEECDCGTPENCQNECCDA ATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQC YDLFGADVYEAEDSCFERNQKGNYYGYCRKENGNKIPCAPEDVKCGRLYCKDNSPGQNNPCKMFYSNEDEHKGMVLPGTK CADGKVCSNGHCVDVATAY ; _struct_ref.pdbx_align_begin 191 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 2DW2 A 1 ? 419 ? Q90282 191 ? 609 ? 191 609 2 1 2DW2 B 1 ? 419 ? Q90282 191 ? 609 ? 191 609 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 2DW2 VAL A 13 ? UNP Q90282 PHE 203 'SEE REMARK 999' 203 1 2 2DW2 VAL B 13 ? UNP Q90282 PHE 203 'SEE REMARK 999' 203 2 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CA non-polymer . 'CALCIUM ION' ? 'Ca 2' 40.078 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FUC saccharide . ALPHA-L-FUCOSE ? 'C6 H12 O5' 164.156 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.entry_id 2DW2 _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.74 _exptl_crystal.density_percent_sol 55.13 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 6.5 _exptl_crystal_grow.pdbx_details ;4% n-propanol, 16.2% PEG8000, 0.18M calcium acetate, 0.09M sodium cacodylate, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K ; _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 90 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 315' _diffrn_detector.pdbx_collection_date 2005-11-20 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'rotated-inclined double-crystal monochromator' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.0 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'SPRING-8 BEAMLINE BL41XU' _diffrn_source.pdbx_synchrotron_site SPring-8 _diffrn_source.pdbx_synchrotron_beamline BL41XU _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.0 # _reflns.entry_id 2DW2 _reflns.observed_criterion_sigma_F 0 _reflns.observed_criterion_sigma_I 0 _reflns.d_resolution_high 2.7 _reflns.d_resolution_low 50 _reflns.number_all 28047 _reflns.number_obs 26911 _reflns.percent_possible_obs 95.9 _reflns.pdbx_Rmerge_I_obs 0.085 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 10.1 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 3.4 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 2.7 _reflns_shell.d_res_low 2.8 _reflns_shell.percent_possible_all 82.5 _reflns_shell.Rmerge_I_obs 0.231 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 5.5 _reflns_shell.pdbx_redundancy 2.8 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 2313 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 2DW2 _refine.ls_d_res_high 2.7 _refine.ls_d_res_low 50 _refine.pdbx_ls_sigma_F 0 _refine.pdbx_ls_sigma_I ? _refine.ls_number_reflns_all 28047 _refine.ls_number_reflns_obs 26907 _refine.ls_number_reflns_R_free 1334 _refine.ls_percent_reflns_obs 95.8 _refine.ls_R_factor_all ? _refine.ls_R_factor_obs ? _refine.ls_R_factor_R_work 0.199 _refine.ls_R_factor_R_free 0.26 _refine.ls_redundancy_reflns_obs ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.ls_percent_reflns_R_free ? _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_starting_model 2ERO _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_R_Free_selection_details random _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.solvent_model_details ? _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.pdbx_isotropic_thermal_model ? _refine.B_iso_mean ? _refine.aniso_B[1][1] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][2] ? _refine.aniso_B[2][3] ? _refine.aniso_B[3][3] ? _refine.details ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_overall_ESU_R ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6438 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 234 _refine_hist.number_atoms_solvent 151 _refine_hist.number_atoms_total 6823 _refine_hist.d_res_high 2.7 _refine_hist.d_res_low 50 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d 0.005 ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg 1.14 ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d 22.9 ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d 0.73 ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used ? _refine_ls_shell.d_res_high 2.7 _refine_ls_shell.d_res_low 2.8 _refine_ls_shell.number_reflns_R_work ? _refine_ls_shell.R_factor_R_work 0.264 _refine_ls_shell.percent_reflns_obs 81.7 _refine_ls_shell.R_factor_R_free 0.328 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 112 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.number_reflns_obs 2276 _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # _struct.entry_id 2DW2 _struct.title 'Crystal structure of VAP2 from Crotalus atrox venom (Form 2-5 crystal)' _struct.pdbx_descriptor Catrocollastatin _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 2DW2 _struct_keywords.pdbx_keywords 'APOPTOSIS, TOXIN' _struct_keywords.text 'apoptotic toxin, SVMP, metalloproteinase, APOPTOSIS, TOXIN' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 2 ? E N N 3 ? F N N 2 ? G N N 4 ? H N N 2 ? I N N 4 ? J N N 2 ? K N N 5 ? L N N 6 ? M N N 7 ? N N N 7 ? O N N 7 ? P N N 2 ? Q N N 2 ? R N N 3 ? S N N 2 ? T N N 4 ? U N N 2 ? V N N 4 ? W N N 2 ? X N N 5 ? Y N N 6 ? Z N N 7 ? AA N N 7 ? BA N N 7 ? CA N N 8 ? DA N N 8 ? # _struct_biol.id 1 # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 ASP A 17 ? ASN A 24 ? ASP A 207 ASN A 214 1 ? 8 HELX_P HELX_P2 2 ASP A 27 ? TYR A 46 ? ASP A 217 TYR A 236 1 ? 20 HELX_P HELX_P3 3 GLU A 72 ? ASP A 87 ? GLU A 262 ASP A 277 1 ? 16 HELX_P HELX_P4 4 LEU A 88 ? ARG A 91 ? LEU A 278 ARG A 281 5 ? 4 HELX_P HELX_P5 5 ILE A 133 ? LEU A 149 ? ILE A 323 LEU A 339 1 ? 17 HELX_P HELX_P6 6 SER A 180 ? HIS A 194 ? SER A 370 HIS A 384 1 ? 15 HELX_P HELX_P7 7 PRO A 196 ? LEU A 200 ? PRO A 386 LEU A 390 5 ? 5 HELX_P HELX_P8 8 LEU A 204 ? ILE A 208 ? LEU A 394 ILE A 398 5 ? 5 HELX_P HELX_P9 9 ILE A 315 ? GLY A 325 ? ILE A 505 GLY A 515 1 ? 11 HELX_P HELX_P10 10 GLU A 332 ? LYS A 341 ? GLU A 522 LYS A 531 5 ? 10 HELX_P HELX_P11 11 ALA A 359 ? GLY A 366 ? ALA A 549 GLY A 556 5 ? 8 HELX_P HELX_P12 12 ALA A 416 ? ALA A 418 ? ALA A 606 ALA A 608 5 ? 3 HELX_P HELX_P13 13 ASP B 17 ? ASN B 24 ? ASP B 207 ASN B 214 1 ? 8 HELX_P HELX_P14 14 ASP B 27 ? TYR B 46 ? ASP B 217 TYR B 236 1 ? 20 HELX_P HELX_P15 15 GLU B 72 ? THR B 86 ? GLU B 262 THR B 276 1 ? 15 HELX_P HELX_P16 16 ASP B 87 ? LYS B 92 ? ASP B 277 LYS B 282 1 ? 6 HELX_P HELX_P17 17 ILE B 133 ? LEU B 149 ? ILE B 323 LEU B 339 1 ? 17 HELX_P HELX_P18 18 SER B 180 ? HIS B 194 ? SER B 370 HIS B 384 1 ? 15 HELX_P HELX_P19 19 PRO B 196 ? LEU B 200 ? PRO B 386 LEU B 390 5 ? 5 HELX_P HELX_P20 20 ILE B 315 ? GLY B 325 ? ILE B 505 GLY B 515 1 ? 11 HELX_P HELX_P21 21 GLU B 332 ? GLU B 337 ? GLU B 522 GLU B 527 1 ? 6 HELX_P HELX_P22 22 ARG B 338 ? LYS B 341 ? ARG B 528 LYS B 531 5 ? 4 HELX_P HELX_P23 23 ASP B 362 ? GLY B 366 ? ASP B 552 GLY B 556 5 ? 5 HELX_P HELX_P24 24 ALA B 416 ? ALA B 418 ? ALA B 606 ALA B 608 5 ? 3 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 118 SG ? ? ? 1_555 A CYS 198 SG ? ? A CYS 308 A CYS 388 1_555 ? ? ? ? ? ? ? 2.030 ? disulf2 disulf ? ? A CYS 158 SG ? ? ? 1_555 A CYS 182 SG ? ? A CYS 348 A CYS 372 1_555 ? ? ? ? ? ? ? 2.039 ? disulf3 disulf ? ? A CYS 160 SG ? ? ? 1_555 A CYS 165 SG ? ? A CYS 350 A CYS 355 1_555 ? ? ? ? ? ? ? 2.035 ? disulf4 disulf ? ? A CYS 214 SG ? ? ? 1_555 A CYS 243 SG ? ? A CYS 404 A CYS 433 1_555 ? ? ? ? ? ? ? 2.033 ? disulf5 disulf ? ? A CYS 225 SG ? ? ? 1_555 A CYS 238 SG ? ? A CYS 415 A CYS 428 1_555 ? ? ? ? ? ? ? 2.032 ? disulf6 disulf ? ? A CYS 227 SG ? ? ? 1_555 A CYS 233 SG ? ? A CYS 417 A CYS 423 1_555 ? ? ? ? ? ? ? 2.040 ? disulf7 disulf ? ? A CYS 237 SG ? ? ? 1_555 A CYS 260 SG ? ? A CYS 427 A CYS 450 1_555 ? ? ? ? ? ? ? 2.031 ? disulf8 disulf ? ? A CYS 251 SG ? ? ? 1_555 A CYS 257 SG ? ? A CYS 441 A CYS 447 1_555 ? ? ? ? ? ? ? 2.035 ? disulf9 disulf ? ? A CYS 256 SG ? ? ? 1_555 A CYS 282 SG ? ? A CYS 446 A CYS 472 1_555 ? ? ? ? ? ? ? 2.034 ? disulf10 disulf ? ? A CYS 269 SG ? ? ? 1_555 A CYS 289 SG ? ? A CYS 459 A CYS 479 1_555 ? ? ? ? ? ? ? 2.035 ? disulf11 disulf ? ? A CYS 276 SG ? ? ? 1_555 A CYS 308 SG ? ? A CYS 466 A CYS 498 1_555 ? ? ? ? ? ? ? 2.028 ? disulf12 disulf ? ? A CYS 301 SG ? ? ? 1_555 A CYS 313 SG ? ? A CYS 491 A CYS 503 1_555 ? ? ? ? ? ? ? 2.030 ? disulf13 disulf ? ? A CYS 320 SG ? ? ? 1_555 A CYS 370 SG ? ? A CYS 510 A CYS 560 1_555 ? ? ? ? ? ? ? 2.035 ? disulf14 disulf ? ? A CYS 335 SG ? ? ? 1_555 A CYS 381 SG ? ? A CYS 525 A CYS 571 1_555 ? ? ? ? ? ? ? 2.033 ? disulf15 disulf ? ? A CYS 348 SG ? ? ? 1_555 A CYS 358 SG ? ? A CYS 538 A CYS 548 1_555 ? ? ? ? ? ? ? 2.030 ? disulf16 disulf ? ? A CYS 365 SG ? ? ? 1_555 A CYS 407 SG ? ? A CYS 555 A CYS 597 1_555 ? ? ? ? ? ? ? 2.035 ? disulf17 disulf ? ? A CYS 401 SG ? ? ? 1_555 A CYS 412 SG ? ? A CYS 591 A CYS 602 1_555 ? ? ? ? ? ? ? 2.035 ? disulf18 disulf ? ? B CYS 118 SG ? ? ? 1_555 B CYS 198 SG ? ? B CYS 308 B CYS 388 1_555 ? ? ? ? ? ? ? 2.032 ? disulf19 disulf ? ? B CYS 158 SG ? ? ? 1_555 B CYS 182 SG ? ? B CYS 348 B CYS 372 1_555 ? ? ? ? ? ? ? 2.038 ? disulf20 disulf ? ? B CYS 160 SG ? ? ? 1_555 B CYS 165 SG ? ? B CYS 350 B CYS 355 1_555 ? ? ? ? ? ? ? 2.033 ? disulf21 disulf ? ? B CYS 214 SG ? ? ? 1_555 B CYS 243 SG ? ? B CYS 404 B CYS 433 1_555 ? ? ? ? ? ? ? 2.032 ? disulf22 disulf ? ? B CYS 225 SG ? ? ? 1_555 B CYS 238 SG ? ? B CYS 415 B CYS 428 1_555 ? ? ? ? ? ? ? 2.031 ? disulf23 disulf ? ? B CYS 227 SG ? ? ? 1_555 B CYS 233 SG ? ? B CYS 417 B CYS 423 1_555 ? ? ? ? ? ? ? 2.039 ? disulf24 disulf ? ? B CYS 237 SG ? ? ? 1_555 B CYS 260 SG ? ? B CYS 427 B CYS 450 1_555 ? ? ? ? ? ? ? 2.031 ? disulf25 disulf ? ? B CYS 251 SG ? ? ? 1_555 B CYS 257 SG ? ? B CYS 441 B CYS 447 1_555 ? ? ? ? ? ? ? 2.032 ? disulf26 disulf ? ? B CYS 256 SG ? ? ? 1_555 B CYS 282 SG ? ? B CYS 446 B CYS 472 1_555 ? ? ? ? ? ? ? 2.032 ? disulf27 disulf ? ? B CYS 269 SG ? ? ? 1_555 B CYS 289 SG ? ? B CYS 459 B CYS 479 1_555 ? ? ? ? ? ? ? 2.034 ? disulf28 disulf ? ? B CYS 276 SG ? ? ? 1_555 B CYS 308 SG ? ? B CYS 466 B CYS 498 1_555 ? ? ? ? ? ? ? 2.028 ? disulf29 disulf ? ? B CYS 301 SG ? ? ? 1_555 B CYS 313 SG ? ? B CYS 491 B CYS 503 1_555 ? ? ? ? ? ? ? 2.028 ? disulf30 disulf ? ? B CYS 320 SG ? ? ? 1_555 B CYS 370 SG ? ? B CYS 510 B CYS 560 1_555 ? ? ? ? ? ? ? 2.037 ? disulf31 disulf ? ? B CYS 335 SG ? ? ? 1_555 B CYS 381 SG ? ? B CYS 525 B CYS 571 1_555 ? ? ? ? ? ? ? 2.030 ? disulf32 disulf ? ? B CYS 348 SG ? ? ? 1_555 B CYS 358 SG ? ? B CYS 538 B CYS 548 1_555 ? ? ? ? ? ? ? 2.025 ? disulf33 disulf ? ? B CYS 365 SG ? ? ? 1_555 B CYS 407 SG ? ? B CYS 555 B CYS 597 1_555 ? ? ? ? ? ? ? 2.031 ? disulf34 disulf ? ? B CYS 401 SG ? ? ? 1_555 B CYS 412 SG ? ? B CYS 591 B CYS 602 1_555 ? ? ? ? ? ? ? 2.034 ? covale1 covale ? ? A ASN 181 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 371 A NAG 801 1_555 ? ? ? ? ? ? ? 1.449 ? covale2 covale ? ? B ASN 181 ND2 ? ? ? 1_555 P NAG . C1 ? ? B ASN 371 B NAG 801 1_555 ? ? ? ? ? ? ? 1.448 ? covale3 covale ? ? C NAG . O4 ? ? ? 1_555 D NAG . C1 ? ? A NAG 801 A NAG 802 1_555 ? ? ? ? ? ? ? 1.386 ? covale4 covale ? ? C NAG . O6 ? ? ? 1_555 K FUC . C1 ? ? A NAG 801 A FUC 809 1_555 ? ? ? ? ? ? ? 1.401 ? covale5 covale ? ? D NAG . O4 ? ? ? 1_555 E BMA . C1 ? ? A NAG 802 A BMA 803 1_555 ? ? ? ? ? ? ? 1.376 ? covale6 covale ? ? E BMA . O3 ? ? ? 1_555 G MAN . C1 ? ? A BMA 803 A MAN 805 1_555 ? ? ? ? ? ? ? 1.399 ? covale7 covale ? ? E BMA . O4 ? ? ? 1_555 F NAG . C1 ? ? A BMA 803 A NAG 804 1_555 ? ? ? ? ? ? ? 1.385 ? covale8 covale ? ? E BMA . O6 ? ? ? 1_555 I MAN . C1 ? ? A BMA 803 A MAN 807 1_555 ? ? ? ? ? ? ? 1.396 ? covale9 covale ? ? G MAN . O2 ? ? ? 1_555 H NAG . C1 ? ? A MAN 805 A NAG 806 1_555 ? ? ? ? ? ? ? 1.391 ? covale10 covale ? ? I MAN . O2 ? ? ? 1_555 J NAG . C1 ? ? A MAN 807 A NAG 808 1_555 ? ? ? ? ? ? ? 1.390 ? covale11 covale ? ? P NAG . O4 ? ? ? 1_555 Q NAG . C1 ? ? B NAG 801 B NAG 802 1_555 ? ? ? ? ? ? ? 1.381 ? covale12 covale ? ? P NAG . O6 ? ? ? 1_555 X FUC . C1 ? ? B NAG 801 B FUC 809 1_555 ? ? ? ? ? ? ? 1.406 ? covale13 covale ? ? Q NAG . O4 ? ? ? 1_555 R BMA . C1 ? ? B NAG 802 B BMA 803 1_555 ? ? ? ? ? ? ? 1.392 ? covale14 covale ? ? R BMA . O3 ? ? ? 1_555 T MAN . C1 ? ? B BMA 803 B MAN 805 1_555 ? ? ? ? ? ? ? 1.400 ? covale15 covale ? ? R BMA . O4 ? ? ? 1_555 S NAG . C1 ? ? B BMA 803 B NAG 804 1_555 ? ? ? ? ? ? ? 1.383 ? covale16 covale ? ? R BMA . O6 ? ? ? 1_555 V MAN . C1 ? ? B BMA 803 B MAN 807 1_555 ? ? ? ? ? ? ? 1.397 ? covale17 covale ? ? T MAN . O2 ? ? ? 1_555 U NAG . C1 ? ? B MAN 805 B NAG 806 1_555 ? ? ? ? ? ? ? 1.393 ? covale18 covale ? ? V MAN . O2 ? ? ? 1_555 W NAG . C1 ? ? B MAN 807 B NAG 808 1_555 ? ? ? ? ? ? ? 1.379 ? metalc1 metalc ? ? A HIS 143 NE2 ? ? ? 1_555 L ZN . ZN ? ? A HIS 333 A ZN 700 1_555 ? ? ? ? ? ? ? 2.130 ? metalc2 metalc ? ? A HIS 147 NE2 ? ? ? 1_555 L ZN . ZN ? ? A HIS 337 A ZN 700 1_555 ? ? ? ? ? ? ? 2.118 ? metalc3 metalc ? ? A HIS 153 NE2 ? ? ? 1_555 L ZN . ZN ? ? A HIS 343 A ZN 700 1_555 ? ? ? ? ? ? ? 1.929 ? metalc4 metalc ? ? B HIS 143 NE2 ? ? ? 1_555 Y ZN . ZN ? ? B HIS 333 B ZN 700 1_555 ? ? ? ? ? ? ? 2.029 ? metalc5 metalc ? ? B HIS 147 NE2 ? ? ? 1_555 Y ZN . ZN ? ? B HIS 337 B ZN 700 1_555 ? ? ? ? ? ? ? 2.135 ? metalc6 metalc ? ? B HIS 153 NE2 ? ? ? 1_555 Y ZN . ZN ? ? B HIS 343 B ZN 700 1_555 ? ? ? ? ? ? ? 1.967 ? metalc7 metalc ? ? L ZN . ZN ? ? ? 1_555 CA HOH . O ? ? A ZN 700 A HOH 153 1_555 ? ? ? ? ? ? ? 2.027 ? metalc8 metalc ? ? M CA . CA ? ? ? 1_555 A GLU 11 OE1 ? ? A CA 701 A GLU 201 1_555 ? ? ? ? ? ? ? 2.130 ? metalc9 metalc ? ? M CA . CA ? ? ? 1_555 A ASP 95 OD1 ? ? A CA 701 A ASP 285 1_555 ? ? ? ? ? ? ? 2.352 ? metalc10 metalc ? ? M CA . CA ? ? ? 1_555 A ASP 95 OD2 ? ? A CA 701 A ASP 285 1_555 ? ? ? ? ? ? ? 2.668 ? metalc11 metalc ? ? M CA . CA ? ? ? 1_555 A CYS 198 O ? ? A CA 701 A CYS 388 1_555 ? ? ? ? ? ? ? 2.106 ? metalc12 metalc ? ? M CA . CA ? ? ? 1_555 A ASN 201 ND2 ? ? A CA 701 A ASN 391 1_555 ? ? ? ? ? ? ? 2.412 ? metalc13 metalc ? ? M CA . CA ? ? ? 1_555 CA HOH . O ? ? A CA 701 A HOH 86 1_555 ? ? ? ? ? ? ? 2.501 ? metalc14 metalc ? ? M CA . CA ? ? ? 1_555 CA HOH . O ? ? A CA 701 A HOH 4 1_555 ? ? ? ? ? ? ? 2.130 ? metalc15 metalc ? ? M CA . CA ? ? ? 1_555 A ASN 201 OD1 ? ? A CA 701 A ASN 391 1_555 ? ? ? ? ? ? ? 2.758 ? metalc16 metalc ? ? N CA . CA ? ? ? 1_555 A VAL 213 O ? ? A CA 702 A VAL 403 1_555 ? ? ? ? ? ? ? 2.305 ? metalc17 metalc ? ? N CA . CA ? ? ? 1_555 A ASN 216 OD1 ? ? A CA 702 A ASN 406 1_555 ? ? ? ? ? ? ? 2.415 ? metalc18 metalc ? ? N CA . CA ? ? ? 1_555 A GLU 220 OE1 ? ? A CA 702 A GLU 410 1_555 ? ? ? ? ? ? ? 2.310 ? metalc19 metalc ? ? N CA . CA ? ? ? 1_555 A LEU 218 O ? ? A CA 702 A LEU 408 1_555 ? ? ? ? ? ? ? 2.365 ? metalc20 metalc ? ? N CA . CA ? ? ? 1_555 A GLU 223 OE1 ? ? A CA 702 A GLU 413 1_555 ? ? ? ? ? ? ? 2.511 ? metalc21 metalc ? ? N CA . CA ? ? ? 1_555 A GLU 223 OE2 ? ? A CA 702 A GLU 413 1_555 ? ? ? ? ? ? ? 2.875 ? metalc22 metalc ? ? N CA . CA ? ? ? 1_555 A ASP 226 OD2 ? ? A CA 702 A ASP 416 1_555 ? ? ? ? ? ? ? 2.382 ? metalc23 metalc ? ? O CA . CA ? ? ? 1_555 A GLU 280 OE1 ? ? A CA 703 A GLU 470 1_555 ? ? ? ? ? ? ? 2.231 ? metalc24 metalc ? ? O CA . CA ? ? ? 1_555 A PRO 278 O ? ? A CA 703 A PRO 468 1_555 ? ? ? ? ? ? ? 2.400 ? metalc25 metalc ? ? O CA . CA ? ? ? 1_555 A ASP 292 OD2 ? ? A CA 703 A ASP 482 1_555 ? ? ? ? ? ? ? 2.373 ? metalc26 metalc ? ? O CA . CA ? ? ? 1_555 A GLU 280 OE2 ? ? A CA 703 A GLU 470 1_555 ? ? ? ? ? ? ? 2.698 ? metalc27 metalc ? ? O CA . CA ? ? ? 1_555 A VAL 293 O ? ? A CA 703 A VAL 483 1_555 ? ? ? ? ? ? ? 2.854 ? metalc28 metalc ? ? O CA . CA ? ? ? 1_555 A ASP 277 OD2 ? ? A CA 703 A ASP 467 1_555 ? ? ? ? ? ? ? 2.462 ? metalc29 metalc ? ? Y ZN . ZN ? ? ? 1_555 DA HOH . O ? ? B ZN 700 B HOH 155 1_555 ? ? ? ? ? ? ? 2.163 ? metalc30 metalc ? ? Z CA . CA ? ? ? 1_555 B ASP 95 OD2 ? ? B CA 711 B ASP 285 1_555 ? ? ? ? ? ? ? 2.644 ? metalc31 metalc ? ? Z CA . CA ? ? ? 1_555 B ASN 201 OD1 ? ? B CA 711 B ASN 391 1_555 ? ? ? ? ? ? ? 3.040 ? metalc32 metalc ? ? Z CA . CA ? ? ? 1_555 B ASP 95 OD1 ? ? B CA 711 B ASP 285 1_555 ? ? ? ? ? ? ? 2.401 ? metalc33 metalc ? ? Z CA . CA ? ? ? 1_555 B GLU 11 OE1 ? ? B CA 711 B GLU 201 1_555 ? ? ? ? ? ? ? 2.358 ? metalc34 metalc ? ? Z CA . CA ? ? ? 1_555 B CYS 198 O ? ? B CA 711 B CYS 388 1_555 ? ? ? ? ? ? ? 2.405 ? metalc35 metalc ? ? Z CA . CA ? ? ? 1_555 B ASN 201 ND2 ? ? B CA 711 B ASN 391 1_555 ? ? ? ? ? ? ? 2.347 ? metalc36 metalc ? ? AA CA . CA ? ? ? 1_555 B LEU 218 O ? ? B CA 712 B LEU 408 1_555 ? ? ? ? ? ? ? 2.441 ? metalc37 metalc ? ? AA CA . CA ? ? ? 1_555 B ASP 226 OD2 ? ? B CA 712 B ASP 416 1_555 ? ? ? ? ? ? ? 2.263 ? metalc38 metalc ? ? AA CA . CA ? ? ? 1_555 B ASN 216 OD1 ? ? B CA 712 B ASN 406 1_555 ? ? ? ? ? ? ? 2.263 ? metalc39 metalc ? ? AA CA . CA ? ? ? 1_555 B VAL 213 O ? ? B CA 712 B VAL 403 1_555 ? ? ? ? ? ? ? 2.355 ? metalc40 metalc ? ? AA CA . CA ? ? ? 1_555 B GLU 220 OE1 ? ? B CA 712 B GLU 410 1_555 ? ? ? ? ? ? ? 2.349 ? metalc41 metalc ? ? AA CA . CA ? ? ? 1_555 B GLU 223 OE1 ? ? B CA 712 B GLU 413 1_555 ? ? ? ? ? ? ? 2.457 ? metalc42 metalc ? ? AA CA . CA ? ? ? 1_555 B GLU 223 OE2 ? ? B CA 712 B GLU 413 1_555 ? ? ? ? ? ? ? 2.855 ? metalc43 metalc ? ? BA CA . CA ? ? ? 1_555 B VAL 293 O ? ? B CA 713 B VAL 483 1_555 ? ? ? ? ? ? ? 2.581 ? metalc44 metalc ? ? BA CA . CA ? ? ? 1_555 B GLU 280 OE2 ? ? B CA 713 B GLU 470 1_555 ? ? ? ? ? ? ? 2.908 ? metalc45 metalc ? ? BA CA . CA ? ? ? 1_555 B PRO 278 O ? ? B CA 713 B PRO 468 1_555 ? ? ? ? ? ? ? 2.319 ? metalc46 metalc ? ? BA CA . CA ? ? ? 1_555 B ASP 292 OD1 ? ? B CA 713 B ASP 482 1_555 ? ? ? ? ? ? ? 2.276 ? metalc47 metalc ? ? BA CA . CA ? ? ? 1_555 B GLU 280 OE1 ? ? B CA 713 B GLU 470 1_555 ? ? ? ? ? ? ? 2.354 ? metalc48 metalc ? ? BA CA . CA ? ? ? 1_555 B ASP 277 OD2 ? ? B CA 713 B ASP 467 1_555 ? ? ? ? ? ? ? 2.244 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 5 ? B ? 2 ? C ? 2 ? D ? 2 ? E ? 2 ? F ? 2 ? G ? 3 ? H ? 5 ? I ? 2 ? J ? 2 ? K ? 2 ? L ? 2 ? M ? 2 ? N ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? parallel A 4 5 ? anti-parallel B 1 2 ? anti-parallel C 1 2 ? anti-parallel D 1 2 ? anti-parallel E 1 2 ? anti-parallel F 1 2 ? anti-parallel G 1 2 ? anti-parallel G 2 3 ? anti-parallel H 1 2 ? parallel H 2 3 ? parallel H 3 4 ? parallel H 4 5 ? anti-parallel I 1 2 ? anti-parallel J 1 2 ? anti-parallel K 1 2 ? anti-parallel L 1 2 ? anti-parallel M 1 2 ? anti-parallel N 1 2 ? anti-parallel N 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 ILE A 51 ? ILE A 60 ? ILE A 241 ILE A 250 A 2 ARG A 8 ? VAL A 16 ? ARG A 198 VAL A 206 A 3 ASN A 96 ? THR A 101 ? ASN A 286 THR A 291 A 4 THR A 124 ? GLN A 128 ? THR A 314 GLN A 318 A 5 GLY A 110 ? ALA A 112 ? GLY A 300 ALA A 302 B 1 CYS A 257 ? GLU A 258 ? CYS A 447 GLU A 448 B 2 LYS A 261 ? PHE A 262 ? LYS A 451 PHE A 452 C 1 GLU A 268 ? ARG A 270 ? GLU A 458 ARG A 460 C 2 GLU A 280 ? HIS A 281 ? GLU A 470 HIS A 471 D 1 PRO A 300 ? CYS A 301 ? PRO A 490 CYS A 491 D 2 GLY A 306 ? TYR A 307 ? GLY A 496 TYR A 497 E 1 VAL A 328 ? GLU A 330 ? VAL A 518 GLU A 520 E 2 CYS A 370 ? ASP A 372 ? CYS A 560 ASP A 562 F 1 ARG A 349 ? GLU A 351 ? ARG A 539 GLU A 541 F 2 ASN A 354 ? ILE A 356 ? ASN A 544 ILE A 546 G 1 LYS A 400 ? ALA A 402 ? LYS A 590 ALA A 592 G 2 LYS A 405 ? CYS A 407 ? LYS A 595 CYS A 597 G 3 CYS A 412 ? ASP A 414 ? CYS A 602 ASP A 604 H 1 ILE B 51 ? ILE B 60 ? ILE B 241 ILE B 250 H 2 ARG B 8 ? VAL B 16 ? ARG B 198 VAL B 206 H 3 ASN B 96 ? THR B 101 ? ASN B 286 THR B 291 H 4 THR B 124 ? GLN B 128 ? THR B 314 GLN B 318 H 5 GLY B 110 ? ALA B 112 ? GLY B 300 ALA B 302 I 1 CYS B 257 ? GLU B 258 ? CYS B 447 GLU B 448 I 2 LYS B 261 ? PHE B 262 ? LYS B 451 PHE B 452 J 1 GLU B 268 ? ARG B 270 ? GLU B 458 ARG B 460 J 2 GLU B 280 ? HIS B 281 ? GLU B 470 HIS B 471 K 1 PRO B 300 ? CYS B 301 ? PRO B 490 CYS B 491 K 2 GLY B 306 ? TYR B 307 ? GLY B 496 TYR B 497 L 1 VAL B 328 ? GLU B 330 ? VAL B 518 GLU B 520 L 2 CYS B 370 ? ASP B 372 ? CYS B 560 ASP B 562 M 1 ARG B 349 ? GLU B 351 ? ARG B 539 GLU B 541 M 2 ASN B 354 ? ILE B 356 ? ASN B 544 ILE B 546 N 1 LYS B 400 ? ALA B 402 ? LYS B 590 ALA B 592 N 2 LYS B 405 ? CYS B 407 ? LYS B 595 CYS B 597 N 3 CYS B 412 ? ASP B 414 ? CYS B 602 ASP B 604 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 O HIS A 52 ? O HIS A 242 N ARG A 8 ? N ARG A 198 A 2 3 N VAL A 15 ? N VAL A 205 O LEU A 100 ? O LEU A 290 A 3 4 N THR A 101 ? N THR A 291 O ILE A 127 ? O ILE A 317 A 4 5 O ILE A 126 ? O ILE A 316 N LEU A 111 ? N LEU A 301 B 1 2 N GLU A 258 ? N GLU A 448 O LYS A 261 ? O LYS A 451 C 1 2 N CYS A 269 ? N CYS A 459 O GLU A 280 ? O GLU A 470 D 1 2 N CYS A 301 ? N CYS A 491 O GLY A 306 ? O GLY A 496 E 1 2 N TYR A 329 ? N TYR A 519 O LYS A 371 ? O LYS A 561 F 1 2 N ARG A 349 ? N ARG A 539 O ILE A 356 ? O ILE A 546 G 1 2 N ALA A 402 ? N ALA A 592 O LYS A 405 ? O LYS A 595 G 2 3 N VAL A 406 ? N VAL A 596 O VAL A 413 ? O VAL A 603 H 1 2 O GLY B 57 ? O GLY B 247 N LEU B 14 ? N LEU B 204 H 2 3 N VAL B 15 ? N VAL B 205 O LEU B 100 ? O LEU B 290 H 3 4 N LEU B 99 ? N LEU B 289 O ILE B 127 ? O ILE B 317 H 4 5 O ILE B 126 ? O ILE B 316 N LEU B 111 ? N LEU B 301 I 1 2 N GLU B 258 ? N GLU B 448 O LYS B 261 ? O LYS B 451 J 1 2 N CYS B 269 ? N CYS B 459 O GLU B 280 ? O GLU B 470 K 1 2 N CYS B 301 ? N CYS B 491 O GLY B 306 ? O GLY B 496 L 1 2 N TYR B 329 ? N TYR B 519 O LYS B 371 ? O LYS B 561 M 1 2 N ARG B 349 ? N ARG B 539 O ILE B 356 ? O ILE B 546 N 1 2 N ALA B 402 ? N ALA B 592 O LYS B 405 ? O LYS B 595 N 2 3 N VAL B 406 ? N VAL B 596 O VAL B 413 ? O VAL B 603 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG A 801' AC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 802' AC3 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE BMA A 803' AC4 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE NAG A 804' AC5 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE MAN A 805' AC6 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG A 806' AC7 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE MAN A 807' AC8 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 808' AC9 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE FUC A 809' BC1 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG B 801' BC2 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG B 802' BC3 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE BMA B 803' BC4 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG B 804' BC5 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE MAN B 805' BC6 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE NAG B 806' BC7 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE MAN B 807' BC8 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG B 808' BC9 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE FUC B 809' CC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE ZN A 700' CC2 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA A 701' CC3 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA A 702' CC4 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE CA A 703' CC5 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE ZN B 700' CC6 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE CA B 711' CC7 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA B 712' CC8 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE CA B 713' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 6 TYR A 157 ? TYR A 347 . ? 1_555 ? 2 AC1 6 SER A 159 ? SER A 349 . ? 1_555 ? 3 AC1 6 ASN A 181 ? ASN A 371 . ? 1_555 ? 4 AC1 6 PHE A 185 ? PHE A 375 . ? 1_555 ? 5 AC1 6 NAG D . ? NAG A 802 . ? 1_555 ? 6 AC1 6 FUC K . ? FUC A 809 . ? 1_555 ? 7 AC2 5 HOH CA . ? HOH A 131 . ? 1_555 ? 8 AC2 5 TYR A 157 ? TYR A 347 . ? 1_555 ? 9 AC2 5 NAG C . ? NAG A 801 . ? 1_555 ? 10 AC2 5 BMA E . ? BMA A 803 . ? 1_555 ? 11 AC2 5 FUC K . ? FUC A 809 . ? 1_555 ? 12 AC3 5 TYR A 157 ? TYR A 347 . ? 1_555 ? 13 AC3 5 NAG D . ? NAG A 802 . ? 1_555 ? 14 AC3 5 NAG F . ? NAG A 804 . ? 1_555 ? 15 AC3 5 MAN G . ? MAN A 805 . ? 1_555 ? 16 AC3 5 MAN I . ? MAN A 807 . ? 1_555 ? 17 AC4 8 HOH CA . ? HOH A 89 . ? 1_555 ? 18 AC4 8 TYR A 157 ? TYR A 347 . ? 1_555 ? 19 AC4 8 BMA E . ? BMA A 803 . ? 1_555 ? 20 AC4 8 MAN G . ? MAN A 805 . ? 1_555 ? 21 AC4 8 NAG H . ? NAG A 806 . ? 1_555 ? 22 AC4 8 GLY B 156 ? GLY B 346 . ? 1_554 ? 23 AC4 8 TYR B 157 ? TYR B 347 . ? 1_554 ? 24 AC4 8 ARG B 168 ? ARG B 358 . ? 1_554 ? 25 AC5 6 BMA E . ? BMA A 803 . ? 1_555 ? 26 AC5 6 NAG F . ? NAG A 804 . ? 1_555 ? 27 AC5 6 NAG H . ? NAG A 806 . ? 1_555 ? 28 AC5 6 MET B 273 ? MET B 463 . ? 1_555 ? 29 AC5 6 SER B 274 ? SER B 464 . ? 1_555 ? 30 AC5 6 GLU B 275 ? GLU B 465 . ? 1_555 ? 31 AC6 6 HOH CA . ? HOH A 89 . ? 1_555 ? 32 AC6 6 NAG F . ? NAG A 804 . ? 1_555 ? 33 AC6 6 MAN G . ? MAN A 805 . ? 1_555 ? 34 AC6 6 PRO B 169 ? PRO B 359 . ? 1_554 ? 35 AC6 6 GLU B 275 ? GLU B 465 . ? 1_555 ? 36 AC6 6 LEU B 302 ? LEU B 492 . ? 1_555 ? 37 AC7 2 BMA E . ? BMA A 803 . ? 1_555 ? 38 AC7 2 NAG J . ? NAG A 808 . ? 1_555 ? 39 AC8 2 HOH CA . ? HOH A 131 . ? 1_555 ? 40 AC8 2 MAN I . ? MAN A 807 . ? 1_555 ? 41 AC9 3 SER A 159 ? SER A 349 . ? 1_555 ? 42 AC9 3 NAG C . ? NAG A 801 . ? 1_555 ? 43 AC9 3 NAG D . ? NAG A 802 . ? 1_555 ? 44 BC1 5 TYR B 157 ? TYR B 347 . ? 1_555 ? 45 BC1 5 ASN B 181 ? ASN B 371 . ? 1_555 ? 46 BC1 5 PHE B 185 ? PHE B 375 . ? 1_555 ? 47 BC1 5 NAG Q . ? NAG B 802 . ? 1_555 ? 48 BC1 5 FUC X . ? FUC B 809 . ? 1_555 ? 49 BC2 4 TYR B 157 ? TYR B 347 . ? 1_555 ? 50 BC2 4 NAG P . ? NAG B 801 . ? 1_555 ? 51 BC2 4 BMA R . ? BMA B 803 . ? 1_555 ? 52 BC2 4 FUC X . ? FUC B 809 . ? 1_555 ? 53 BC3 5 TYR B 157 ? TYR B 347 . ? 1_555 ? 54 BC3 5 NAG Q . ? NAG B 802 . ? 1_555 ? 55 BC3 5 NAG S . ? NAG B 804 . ? 1_555 ? 56 BC3 5 MAN T . ? MAN B 805 . ? 1_555 ? 57 BC3 5 MAN V . ? MAN B 807 . ? 1_555 ? 58 BC4 6 GLY A 156 ? GLY A 346 . ? 1_556 ? 59 BC4 6 TYR A 157 ? TYR A 347 . ? 1_556 ? 60 BC4 6 ARG A 168 ? ARG A 358 . ? 1_556 ? 61 BC4 6 BMA R . ? BMA B 803 . ? 1_555 ? 62 BC4 6 MAN T . ? MAN B 805 . ? 1_555 ? 63 BC4 6 NAG U . ? NAG B 806 . ? 1_555 ? 64 BC5 6 MET A 273 ? MET A 463 . ? 1_555 ? 65 BC5 6 SER A 274 ? SER A 464 . ? 1_555 ? 66 BC5 6 GLU A 275 ? GLU A 465 . ? 1_555 ? 67 BC5 6 BMA R . ? BMA B 803 . ? 1_555 ? 68 BC5 6 NAG S . ? NAG B 804 . ? 1_555 ? 69 BC5 6 NAG U . ? NAG B 806 . ? 1_555 ? 70 BC6 7 HOH CA . ? HOH A 67 . ? 1_556 ? 71 BC6 7 PRO A 169 ? PRO A 359 . ? 1_556 ? 72 BC6 7 GLU A 275 ? GLU A 465 . ? 1_555 ? 73 BC6 7 LEU A 302 ? LEU A 492 . ? 1_555 ? 74 BC6 7 ASP A 303 ? ASP A 493 . ? 1_555 ? 75 BC6 7 NAG S . ? NAG B 804 . ? 1_555 ? 76 BC6 7 MAN T . ? MAN B 805 . ? 1_555 ? 77 BC7 3 HOH DA . ? HOH B 123 . ? 1_555 ? 78 BC7 3 BMA R . ? BMA B 803 . ? 1_555 ? 79 BC7 3 NAG W . ? NAG B 808 . ? 1_555 ? 80 BC8 1 MAN V . ? MAN B 807 . ? 1_555 ? 81 BC9 3 SER B 159 ? SER B 349 . ? 1_555 ? 82 BC9 3 NAG P . ? NAG B 801 . ? 1_555 ? 83 BC9 3 NAG Q . ? NAG B 802 . ? 1_555 ? 84 CC1 4 HOH CA . ? HOH A 153 . ? 1_555 ? 85 CC1 4 HIS A 143 ? HIS A 333 . ? 1_555 ? 86 CC1 4 HIS A 147 ? HIS A 337 . ? 1_555 ? 87 CC1 4 HIS A 153 ? HIS A 343 . ? 1_555 ? 88 CC2 6 HOH CA . ? HOH A 4 . ? 1_555 ? 89 CC2 6 HOH CA . ? HOH A 86 . ? 1_555 ? 90 CC2 6 GLU A 11 ? GLU A 201 . ? 1_555 ? 91 CC2 6 ASP A 95 ? ASP A 285 . ? 1_555 ? 92 CC2 6 CYS A 198 ? CYS A 388 . ? 1_555 ? 93 CC2 6 ASN A 201 ? ASN A 391 . ? 1_555 ? 94 CC3 6 VAL A 213 ? VAL A 403 . ? 1_555 ? 95 CC3 6 ASN A 216 ? ASN A 406 . ? 1_555 ? 96 CC3 6 LEU A 218 ? LEU A 408 . ? 1_555 ? 97 CC3 6 GLU A 220 ? GLU A 410 . ? 1_555 ? 98 CC3 6 GLU A 223 ? GLU A 413 . ? 1_555 ? 99 CC3 6 ASP A 226 ? ASP A 416 . ? 1_555 ? 100 CC4 5 ASP A 277 ? ASP A 467 . ? 1_555 ? 101 CC4 5 PRO A 278 ? PRO A 468 . ? 1_555 ? 102 CC4 5 GLU A 280 ? GLU A 470 . ? 1_555 ? 103 CC4 5 ASP A 292 ? ASP A 482 . ? 1_555 ? 104 CC4 5 VAL A 293 ? VAL A 483 . ? 1_555 ? 105 CC5 4 HOH DA . ? HOH B 155 . ? 1_555 ? 106 CC5 4 HIS B 143 ? HIS B 333 . ? 1_555 ? 107 CC5 4 HIS B 147 ? HIS B 337 . ? 1_555 ? 108 CC5 4 HIS B 153 ? HIS B 343 . ? 1_555 ? 109 CC6 4 GLU B 11 ? GLU B 201 . ? 1_555 ? 110 CC6 4 ASP B 95 ? ASP B 285 . ? 1_555 ? 111 CC6 4 CYS B 198 ? CYS B 388 . ? 1_555 ? 112 CC6 4 ASN B 201 ? ASN B 391 . ? 1_555 ? 113 CC7 6 VAL B 213 ? VAL B 403 . ? 1_555 ? 114 CC7 6 ASN B 216 ? ASN B 406 . ? 1_555 ? 115 CC7 6 LEU B 218 ? LEU B 408 . ? 1_555 ? 116 CC7 6 GLU B 220 ? GLU B 410 . ? 1_555 ? 117 CC7 6 GLU B 223 ? GLU B 413 . ? 1_555 ? 118 CC7 6 ASP B 226 ? ASP B 416 . ? 1_555 ? 119 CC8 5 ASP B 277 ? ASP B 467 . ? 1_555 ? 120 CC8 5 PRO B 278 ? PRO B 468 . ? 1_555 ? 121 CC8 5 GLU B 280 ? GLU B 470 . ? 1_555 ? 122 CC8 5 ASP B 292 ? ASP B 482 . ? 1_555 ? 123 CC8 5 VAL B 293 ? VAL B 483 . ? 1_555 ? # _database_PDB_matrix.entry_id 2DW2 _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 2DW2 _atom_sites.fract_transf_matrix[1][1] 0.004530 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000137 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.012583 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.017046 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C CA N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ASN A 1 5 ? 93.117 9.929 48.169 1.00 44.35 ? 195 ASN A N 1 ATOM 2 C CA . ASN A 1 5 ? 93.042 9.275 46.828 1.00 47.75 ? 195 ASN A CA 1 ATOM 3 C C . ASN A 1 5 ? 91.982 9.917 45.935 1.00 45.09 ? 195 ASN A C 1 ATOM 4 O O . ASN A 1 5 ? 90.800 9.956 46.279 1.00 46.98 ? 195 ASN A O 1 ATOM 5 C CB . ASN A 1 5 ? 92.745 7.780 46.982 1.00 50.41 ? 195 ASN A CB 1 ATOM 6 C CG . ASN A 1 5 ? 92.426 7.110 45.656 1.00 53.57 ? 195 ASN A CG 1 ATOM 7 O OD1 . ASN A 1 5 ? 93.185 7.218 44.690 1.00 51.13 ? 195 ASN A OD1 1 ATOM 8 N ND2 . ASN A 1 5 ? 91.297 6.410 45.604 1.00 52.95 ? 195 ASN A ND2 1 ATOM 9 N N . PRO A 1 6 ? 92.399 10.424 44.766 1.00 42.13 ? 196 PRO A N 1 ATOM 10 C CA . PRO A 1 6 ? 91.500 11.074 43.807 1.00 39.72 ? 196 PRO A CA 1 ATOM 11 C C . PRO A 1 6 ? 90.708 10.112 42.921 1.00 37.10 ? 196 PRO A C 1 ATOM 12 O O . PRO A 1 6 ? 89.588 10.414 42.512 1.00 37.15 ? 196 PRO A O 1 ATOM 13 C CB . PRO A 1 6 ? 92.454 11.944 42.998 1.00 39.36 ? 196 PRO A CB 1 ATOM 14 C CG . PRO A 1 6 ? 93.676 11.080 42.924 1.00 35.56 ? 196 PRO A CG 1 ATOM 15 C CD . PRO A 1 6 ? 93.805 10.552 44.338 1.00 36.64 ? 196 PRO A CD 1 ATOM 16 N N . PHE A 1 7 ? 91.299 8.956 42.634 1.00 33.95 ? 197 PHE A N 1 ATOM 17 C CA . PHE A 1 7 ? 90.684 7.941 41.780 1.00 27.41 ? 197 PHE A CA 1 ATOM 18 C C . PHE A 1 7 ? 89.314 7.410 42.187 1.00 23.94 ? 197 PHE A C 1 ATOM 19 O O . PHE A 1 7 ? 89.009 7.259 43.367 1.00 23.11 ? 197 PHE A O 1 ATOM 20 C CB . PHE A 1 7 ? 91.638 6.758 41.627 1.00 22.80 ? 197 PHE A CB 1 ATOM 21 C CG . PHE A 1 7 ? 92.608 6.909 40.502 1.00 18.74 ? 197 PHE A CG 1 ATOM 22 C CD1 . PHE A 1 7 ? 92.236 6.592 39.204 1.00 23.71 ? 197 PHE A CD1 1 ATOM 23 C CD2 . PHE A 1 7 ? 93.889 7.382 40.733 1.00 16.53 ? 197 PHE A CD2 1 ATOM 24 C CE1 . PHE A 1 7 ? 93.131 6.743 38.148 1.00 23.27 ? 197 PHE A CE1 1 ATOM 25 C CE2 . PHE A 1 7 ? 94.792 7.539 39.684 1.00 23.23 ? 197 PHE A CE2 1 ATOM 26 C CZ . PHE A 1 7 ? 94.412 7.219 38.390 1.00 20.28 ? 197 PHE A CZ 1 ATOM 27 N N . ARG A 1 8 ? 88.499 7.125 41.175 1.00 26.15 ? 198 ARG A N 1 ATOM 28 C CA . ARG A 1 8 ? 87.161 6.572 41.353 1.00 21.80 ? 198 ARG A CA 1 ATOM 29 C C . ARG A 1 8 ? 87.203 5.181 40.737 1.00 23.07 ? 198 ARG A C 1 ATOM 30 O O . ARG A 1 8 ? 88.011 4.926 39.844 1.00 26.75 ? 198 ARG A O 1 ATOM 31 C CB . ARG A 1 8 ? 86.126 7.423 40.623 1.00 22.19 ? 198 ARG A CB 1 ATOM 32 C CG . ARG A 1 8 ? 85.802 8.738 41.304 1.00 26.67 ? 198 ARG A CG 1 ATOM 33 C CD . ARG A 1 8 ? 85.097 8.508 42.630 1.00 23.29 ? 198 ARG A CD 1 ATOM 34 N NE . ARG A 1 8 ? 84.542 9.745 43.177 1.00 26.02 ? 198 ARG A NE 1 ATOM 35 C CZ . ARG A 1 8 ? 85.268 10.763 43.629 1.00 25.67 ? 198 ARG A CZ 1 ATOM 36 N NH1 . ARG A 1 8 ? 86.593 10.702 43.606 1.00 23.73 ? 198 ARG A NH1 1 ATOM 37 N NH2 . ARG A 1 8 ? 84.666 11.844 44.105 1.00 25.50 ? 198 ARG A NH2 1 ATOM 38 N N . PHE A 1 9 ? 86.340 4.281 41.199 1.00 23.88 ? 199 PHE A N 1 ATOM 39 C CA . PHE A 1 9 ? 86.344 2.924 40.668 1.00 20.75 ? 199 PHE A CA 1 ATOM 40 C C . PHE A 1 9 ? 84.999 2.485 40.114 1.00 19.16 ? 199 PHE A C 1 ATOM 41 O O . PHE A 1 9 ? 83.983 2.553 40.801 1.00 22.17 ? 199 PHE A O 1 ATOM 42 C CB . PHE A 1 9 ? 86.791 1.933 41.751 1.00 15.08 ? 199 PHE A CB 1 ATOM 43 C CG . PHE A 1 9 ? 88.066 2.321 42.440 1.00 17.12 ? 199 PHE A CG 1 ATOM 44 C CD1 . PHE A 1 9 ? 88.074 3.326 43.407 1.00 20.90 ? 199 PHE A CD1 1 ATOM 45 C CD2 . PHE A 1 9 ? 89.267 1.705 42.106 1.00 20.68 ? 199 PHE A CD2 1 ATOM 46 C CE1 . PHE A 1 9 ? 89.261 3.713 44.031 1.00 13.80 ? 199 PHE A CE1 1 ATOM 47 C CE2 . PHE A 1 9 ? 90.460 2.084 42.724 1.00 20.66 ? 199 PHE A CE2 1 ATOM 48 C CZ . PHE A 1 9 ? 90.455 3.092 43.688 1.00 18.19 ? 199 PHE A CZ 1 ATOM 49 N N . VAL A 1 10 ? 85.001 2.028 38.866 1.00 20.82 ? 200 VAL A N 1 ATOM 50 C CA . VAL A 1 10 ? 83.780 1.554 38.228 1.00 20.30 ? 200 VAL A CA 1 ATOM 51 C C . VAL A 1 10 ? 83.778 0.027 38.205 1.00 21.79 ? 200 VAL A C 1 ATOM 52 O O . VAL A 1 10 ? 84.447 -0.596 37.377 1.00 18.42 ? 200 VAL A O 1 ATOM 53 C CB . VAL A 1 10 ? 83.656 2.059 36.773 1.00 20.99 ? 200 VAL A CB 1 ATOM 54 C CG1 . VAL A 1 10 ? 82.283 1.691 36.219 1.00 24.16 ? 200 VAL A CG1 1 ATOM 55 C CG2 . VAL A 1 10 ? 83.867 3.561 36.715 1.00 18.67 ? 200 VAL A CG2 1 ATOM 56 N N . GLU A 1 11 ? 83.037 -0.572 39.130 1.00 23.97 ? 201 GLU A N 1 ATOM 57 C CA . GLU A 1 11 ? 82.946 -2.024 39.199 1.00 19.30 ? 201 GLU A CA 1 ATOM 58 C C . GLU A 1 11 ? 81.999 -2.448 38.089 1.00 18.55 ? 201 GLU A C 1 ATOM 59 O O . GLU A 1 11 ? 80.777 -2.321 38.206 1.00 13.58 ? 201 GLU A O 1 ATOM 60 C CB . GLU A 1 11 ? 82.421 -2.457 40.568 1.00 17.61 ? 201 GLU A CB 1 ATOM 61 C CG . GLU A 1 11 ? 83.358 -2.098 41.706 1.00 14.16 ? 201 GLU A CG 1 ATOM 62 C CD . GLU A 1 11 ? 82.748 -2.348 43.069 1.00 24.33 ? 201 GLU A CD 1 ATOM 63 O OE1 . GLU A 1 11 ? 81.728 -1.703 43.393 1.00 22.28 ? 201 GLU A OE1 1 ATOM 64 O OE2 . GLU A 1 11 ? 83.286 -3.191 43.819 1.00 27.82 ? 201 GLU A OE2 1 ATOM 65 N N . LEU A 1 12 ? 82.588 -2.948 37.009 1.00 15.31 ? 202 LEU A N 1 ATOM 66 C CA . LEU A 1 12 ? 81.848 -3.361 35.825 1.00 14.02 ? 202 LEU A CA 1 ATOM 67 C C . LEU A 1 12 ? 81.553 -4.851 35.677 1.00 15.50 ? 202 LEU A C 1 ATOM 68 O O . LEU A 1 12 ? 82.310 -5.716 36.132 1.00 17.37 ? 202 LEU A O 1 ATOM 69 C CB . LEU A 1 12 ? 82.605 -2.882 34.580 1.00 7.70 ? 202 LEU A CB 1 ATOM 70 C CG . LEU A 1 12 ? 82.132 -3.343 33.202 1.00 5.97 ? 202 LEU A CG 1 ATOM 71 C CD1 . LEU A 1 12 ? 80.793 -2.714 32.887 1.00 4.83 ? 202 LEU A CD1 1 ATOM 72 C CD2 . LEU A 1 12 ? 83.163 -2.958 32.155 1.00 10.94 ? 202 LEU A CD2 1 ATOM 73 N N . VAL A 1 13 ? 80.433 -5.127 35.020 1.00 13.45 ? 203 VAL A N 1 ATOM 74 C CA . VAL A 1 13 ? 79.999 -6.482 34.722 1.00 15.66 ? 203 VAL A CA 1 ATOM 75 C C . VAL A 1 13 ? 79.685 -6.480 33.227 1.00 17.32 ? 203 VAL A C 1 ATOM 76 O O . VAL A 1 13 ? 78.969 -5.604 32.736 1.00 15.42 ? 203 VAL A O 1 ATOM 77 C CB . VAL A 1 13 ? 78.722 -6.869 35.516 1.00 20.00 ? 203 VAL A CB 1 ATOM 78 C CG1 . VAL A 1 13 ? 78.196 -8.227 35.049 1.00 17.10 ? 203 VAL A CG1 1 ATOM 79 C CG2 . VAL A 1 13 ? 79.037 -6.918 37.000 1.00 22.42 ? 203 VAL A CG2 1 ATOM 80 N N . LEU A 1 14 ? 80.251 -7.436 32.500 1.00 14.40 ? 204 LEU A N 1 ATOM 81 C CA . LEU A 1 14 ? 80.011 -7.539 31.069 1.00 13.03 ? 204 LEU A CA 1 ATOM 82 C C . LEU A 1 14 ? 79.115 -8.719 30.768 1.00 15.70 ? 204 LEU A C 1 ATOM 83 O O . LEU A 1 14 ? 79.312 -9.816 31.294 1.00 12.68 ? 204 LEU A O 1 ATOM 84 C CB . LEU A 1 14 ? 81.318 -7.724 30.301 1.00 14.49 ? 204 LEU A CB 1 ATOM 85 C CG . LEU A 1 14 ? 82.122 -6.489 29.915 1.00 19.35 ? 204 LEU A CG 1 ATOM 86 C CD1 . LEU A 1 14 ? 83.397 -6.931 29.204 1.00 16.67 ? 204 LEU A CD1 1 ATOM 87 C CD2 . LEU A 1 14 ? 81.285 -5.590 29.015 1.00 8.85 ? 204 LEU A CD2 1 ATOM 88 N N . VAL A 1 15 ? 78.129 -8.484 29.913 1.00 16.32 ? 205 VAL A N 1 ATOM 89 C CA . VAL A 1 15 ? 77.212 -9.530 29.508 1.00 14.39 ? 205 VAL A CA 1 ATOM 90 C C . VAL A 1 15 ? 77.405 -9.745 28.013 1.00 14.75 ? 205 VAL A C 1 ATOM 91 O O . VAL A 1 15 ? 77.433 -8.789 27.235 1.00 12.92 ? 205 VAL A O 1 ATOM 92 C CB . VAL A 1 15 ? 75.753 -9.134 29.799 1.00 15.71 ? 205 VAL A CB 1 ATOM 93 C CG1 . VAL A 1 15 ? 74.805 -10.238 29.336 1.00 9.61 ? 205 VAL A CG1 1 ATOM 94 C CG2 . VAL A 1 15 ? 75.583 -8.874 31.286 1.00 13.97 ? 205 VAL A CG2 1 ATOM 95 N N . VAL A 1 16 ? 77.561 -11.004 27.624 1.00 16.24 ? 206 VAL A N 1 ATOM 96 C CA . VAL A 1 16 ? 77.757 -11.362 26.225 1.00 17.60 ? 206 VAL A CA 1 ATOM 97 C C . VAL A 1 16 ? 76.581 -12.212 25.745 1.00 16.23 ? 206 VAL A C 1 ATOM 98 O O . VAL A 1 16 ? 76.290 -13.267 26.314 1.00 14.80 ? 206 VAL A O 1 ATOM 99 C CB . VAL A 1 16 ? 79.081 -12.128 26.045 1.00 12.88 ? 206 VAL A CB 1 ATOM 100 C CG1 . VAL A 1 16 ? 79.260 -12.537 24.601 1.00 14.09 ? 206 VAL A CG1 1 ATOM 101 C CG2 . VAL A 1 16 ? 80.239 -11.251 26.481 1.00 2.21 ? 206 VAL A CG2 1 ATOM 102 N N . ASP A 1 17 ? 75.911 -11.741 24.695 1.00 16.32 ? 207 ASP A N 1 ATOM 103 C CA . ASP A 1 17 ? 74.741 -12.424 24.150 1.00 15.77 ? 207 ASP A CA 1 ATOM 104 C C . ASP A 1 17 ? 75.062 -13.661 23.318 1.00 11.66 ? 207 ASP A C 1 ATOM 105 O O . ASP A 1 17 ? 76.214 -13.935 23.003 1.00 10.46 ? 207 ASP A O 1 ATOM 106 C CB . ASP A 1 17 ? 73.896 -11.439 23.327 1.00 17.85 ? 207 ASP A CB 1 ATOM 107 C CG . ASP A 1 17 ? 74.533 -11.085 21.991 1.00 25.90 ? 207 ASP A CG 1 ATOM 108 O OD1 . ASP A 1 17 ? 75.773 -11.175 21.867 1.00 29.00 ? 207 ASP A OD1 1 ATOM 109 O OD2 . ASP A 1 17 ? 73.790 -10.701 21.063 1.00 25.56 ? 207 ASP A OD2 1 ATOM 110 N N . LYS A 1 18 ? 74.019 -14.405 22.974 1.00 14.99 ? 208 LYS A N 1 ATOM 111 C CA . LYS A 1 18 ? 74.143 -15.630 22.196 1.00 16.63 ? 208 LYS A CA 1 ATOM 112 C C . LYS A 1 18 ? 74.819 -15.403 20.847 1.00 15.87 ? 208 LYS A C 1 ATOM 113 O O . LYS A 1 18 ? 75.695 -16.173 20.445 1.00 17.54 ? 208 LYS A O 1 ATOM 114 C CB . LYS A 1 18 ? 72.753 -16.247 21.992 1.00 15.51 ? 208 LYS A CB 1 ATOM 115 C CG . LYS A 1 18 ? 72.748 -17.578 21.263 1.00 15.74 ? 208 LYS A CG 1 ATOM 116 C CD . LYS A 1 18 ? 73.581 -18.623 21.986 1.00 20.94 ? 208 LYS A CD 1 ATOM 117 C CE . LYS A 1 18 ? 73.418 -19.987 21.331 1.00 14.69 ? 208 LYS A CE 1 ATOM 118 N NZ . LYS A 1 18 ? 71.978 -20.377 21.294 1.00 15.48 ? 208 LYS A NZ 1 ATOM 119 N N . ALA A 1 19 ? 74.409 -14.348 20.149 1.00 12.17 ? 209 ALA A N 1 ATOM 120 C CA . ALA A 1 19 ? 74.983 -14.030 18.845 1.00 11.13 ? 209 ALA A CA 1 ATOM 121 C C . ALA A 1 19 ? 76.501 -13.996 18.949 1.00 6.34 ? 209 ALA A C 1 ATOM 122 O O . ALA A 1 19 ? 77.205 -14.506 18.081 1.00 7.27 ? 209 ALA A O 1 ATOM 123 C CB . ALA A 1 19 ? 74.464 -12.690 18.356 1.00 5.96 ? 209 ALA A CB 1 ATOM 124 N N . MET A 1 20 ? 76.996 -13.387 20.020 1.00 8.89 ? 210 MET A N 1 ATOM 125 C CA . MET A 1 20 ? 78.430 -13.295 20.248 1.00 11.86 ? 210 MET A CA 1 ATOM 126 C C . MET A 1 20 ? 79.046 -14.678 20.348 1.00 11.79 ? 210 MET A C 1 ATOM 127 O O . MET A 1 20 ? 80.120 -14.925 19.799 1.00 15.66 ? 210 MET A O 1 ATOM 128 C CB . MET A 1 20 ? 78.718 -12.518 21.530 1.00 12.73 ? 210 MET A CB 1 ATOM 129 C CG . MET A 1 20 ? 78.793 -11.022 21.338 1.00 13.20 ? 210 MET A CG 1 ATOM 130 S SD . MET A 1 20 ? 80.181 -10.592 20.275 1.00 29.16 ? 210 MET A SD 1 ATOM 131 C CE . MET A 1 20 ? 81.540 -10.653 21.465 1.00 12.71 ? 210 MET A CE 1 ATOM 132 N N . VAL A 1 21 ? 78.364 -15.577 21.050 1.00 10.96 ? 211 VAL A N 1 ATOM 133 C CA . VAL A 1 21 ? 78.859 -16.937 21.212 1.00 10.54 ? 211 VAL A CA 1 ATOM 134 C C . VAL A 1 21 ? 78.903 -17.642 19.864 1.00 11.73 ? 211 VAL A C 1 ATOM 135 O O . VAL A 1 21 ? 79.916 -18.246 19.507 1.00 11.66 ? 211 VAL A O 1 ATOM 136 C CB . VAL A 1 21 ? 77.977 -17.737 22.180 1.00 9.74 ? 211 VAL A CB 1 ATOM 137 C CG1 . VAL A 1 21 ? 78.421 -19.194 22.211 1.00 4.06 ? 211 VAL A CG1 1 ATOM 138 C CG2 . VAL A 1 21 ? 78.071 -17.126 23.569 1.00 10.62 ? 211 VAL A CG2 1 ATOM 139 N N . THR A 1 22 ? 77.805 -17.554 19.117 1.00 12.37 ? 212 THR A N 1 ATOM 140 C CA . THR A 1 22 ? 77.731 -18.170 17.796 1.00 13.58 ? 212 THR A CA 1 ATOM 141 C C . THR A 1 22 ? 78.834 -17.592 16.907 1.00 15.03 ? 212 THR A C 1 ATOM 142 O O . THR A 1 22 ? 79.489 -18.316 16.156 1.00 14.57 ? 212 THR A O 1 ATOM 143 C CB . THR A 1 22 ? 76.372 -17.898 17.130 1.00 10.32 ? 212 THR A CB 1 ATOM 144 O OG1 . THR A 1 22 ? 75.321 -18.309 18.011 1.00 16.63 ? 212 THR A OG1 1 ATOM 145 C CG2 . THR A 1 22 ? 76.255 -18.670 15.819 1.00 3.65 ? 212 THR A CG2 1 ATOM 146 N N . LYS A 1 23 ? 79.034 -16.281 17.005 1.00 12.32 ? 213 LYS A N 1 ATOM 147 C CA . LYS A 1 23 ? 80.057 -15.609 16.220 1.00 15.95 ? 213 LYS A CA 1 ATOM 148 C C . LYS A 1 23 ? 81.434 -16.204 16.493 1.00 17.12 ? 213 LYS A C 1 ATOM 149 O O . LYS A 1 23 ? 82.258 -16.323 15.588 1.00 14.06 ? 213 LYS A O 1 ATOM 150 C CB . LYS A 1 23 ? 80.079 -14.110 16.541 1.00 11.25 ? 213 LYS A CB 1 ATOM 151 C CG . LYS A 1 23 ? 81.080 -13.314 15.705 1.00 6.77 ? 213 LYS A CG 1 ATOM 152 C CD . LYS A 1 23 ? 80.989 -11.827 16.019 1.00 11.99 ? 213 LYS A CD 1 ATOM 153 C CE . LYS A 1 23 ? 81.772 -10.983 15.024 1.00 6.65 ? 213 LYS A CE 1 ATOM 154 N NZ . LYS A 1 23 ? 81.579 -9.522 15.265 1.00 1.00 ? 213 LYS A NZ 1 ATOM 155 N N . ASN A 1 24 ? 81.677 -16.584 17.742 1.00 13.78 ? 214 ASN A N 1 ATOM 156 C CA . ASN A 1 24 ? 82.967 -17.142 18.116 1.00 14.58 ? 214 ASN A CA 1 ATOM 157 C C . ASN A 1 24 ? 82.998 -18.664 18.153 1.00 19.95 ? 214 ASN A C 1 ATOM 158 O O . ASN A 1 24 ? 83.810 -19.268 18.862 1.00 23.86 ? 214 ASN A O 1 ATOM 159 C CB . ASN A 1 24 ? 83.403 -16.559 19.455 1.00 7.83 ? 214 ASN A CB 1 ATOM 160 C CG . ASN A 1 24 ? 83.825 -15.113 19.337 1.00 7.53 ? 214 ASN A CG 1 ATOM 161 O OD1 . ASN A 1 24 ? 85.014 -14.805 19.325 1.00 8.07 ? 214 ASN A OD1 1 ATOM 162 N ND2 . ASN A 1 24 ? 82.850 -14.215 19.224 1.00 5.45 ? 214 ASN A ND2 1 ATOM 163 N N . ASN A 1 25 ? 82.103 -19.274 17.382 1.00 15.36 ? 215 ASN A N 1 ATOM 164 C CA . ASN A 1 25 ? 82.026 -20.724 17.267 1.00 11.44 ? 215 ASN A CA 1 ATOM 165 C C . ASN A 1 25 ? 81.925 -21.480 18.586 1.00 11.91 ? 215 ASN A C 1 ATOM 166 O O . ASN A 1 25 ? 82.370 -22.619 18.683 1.00 10.58 ? 215 ASN A O 1 ATOM 167 C CB . ASN A 1 25 ? 83.236 -21.224 16.483 1.00 11.25 ? 215 ASN A CB 1 ATOM 168 C CG . ASN A 1 25 ? 83.489 -20.406 15.231 1.00 12.55 ? 215 ASN A CG 1 ATOM 169 O OD1 . ASN A 1 25 ? 82.646 -20.344 14.335 1.00 11.85 ? 215 ASN A OD1 1 ATOM 170 N ND2 . ASN A 1 25 ? 84.653 -19.763 15.166 1.00 15.15 ? 215 ASN A ND2 1 ATOM 171 N N . GLY A 1 26 ? 81.343 -20.843 19.597 1.00 14.86 ? 216 GLY A N 1 ATOM 172 C CA . GLY A 1 26 ? 81.179 -21.489 20.888 1.00 15.96 ? 216 GLY A CA 1 ATOM 173 C C . GLY A 1 26 ? 82.401 -21.553 21.786 1.00 21.47 ? 216 GLY A C 1 ATOM 174 O O . GLY A 1 26 ? 82.352 -22.164 22.854 1.00 30.02 ? 216 GLY A O 1 ATOM 175 N N . ASP A 1 27 ? 83.494 -20.920 21.372 1.00 21.95 ? 217 ASP A N 1 ATOM 176 C CA . ASP A 1 27 ? 84.725 -20.930 22.158 1.00 21.17 ? 217 ASP A CA 1 ATOM 177 C C . ASP A 1 27 ? 84.689 -19.877 23.273 1.00 20.10 ? 217 ASP A C 1 ATOM 178 O O . ASP A 1 27 ? 85.220 -18.777 23.120 1.00 15.93 ? 217 ASP A O 1 ATOM 179 C CB . ASP A 1 27 ? 85.921 -20.683 21.234 1.00 20.45 ? 217 ASP A CB 1 ATOM 180 C CG . ASP A 1 27 ? 87.250 -20.845 21.940 1.00 24.50 ? 217 ASP A CG 1 ATOM 181 O OD1 . ASP A 1 27 ? 88.291 -20.646 21.279 1.00 32.05 ? 217 ASP A OD1 1 ATOM 182 O OD2 . ASP A 1 27 ? 87.259 -21.172 23.148 1.00 23.76 ? 217 ASP A OD2 1 ATOM 183 N N . LEU A 1 28 ? 84.069 -20.234 24.395 1.00 19.41 ? 218 LEU A N 1 ATOM 184 C CA . LEU A 1 28 ? 83.931 -19.337 25.542 1.00 17.50 ? 218 LEU A CA 1 ATOM 185 C C . LEU A 1 28 ? 85.269 -18.840 26.074 1.00 18.57 ? 218 LEU A C 1 ATOM 186 O O . LEU A 1 28 ? 85.403 -17.681 26.474 1.00 16.19 ? 218 LEU A O 1 ATOM 187 C CB . LEU A 1 28 ? 83.172 -20.044 26.665 1.00 16.55 ? 218 LEU A CB 1 ATOM 188 C CG . LEU A 1 28 ? 81.907 -20.813 26.265 1.00 13.43 ? 218 LEU A CG 1 ATOM 189 C CD1 . LEU A 1 28 ? 81.165 -21.204 27.526 1.00 6.91 ? 218 LEU A CD1 1 ATOM 190 C CD2 . LEU A 1 28 ? 81.016 -19.965 25.373 1.00 6.81 ? 218 LEU A CD2 1 ATOM 191 N N . ASP A 1 29 ? 86.254 -19.730 26.085 1.00 22.06 ? 219 ASP A N 1 ATOM 192 C CA . ASP A 1 29 ? 87.589 -19.400 26.561 1.00 23.14 ? 219 ASP A CA 1 ATOM 193 C C . ASP A 1 29 ? 88.166 -18.229 25.770 1.00 21.87 ? 219 ASP A C 1 ATOM 194 O O . ASP A 1 29 ? 88.817 -17.344 26.329 1.00 17.15 ? 219 ASP A O 1 ATOM 195 C CB . ASP A 1 29 ? 88.502 -20.617 26.419 1.00 29.46 ? 219 ASP A CB 1 ATOM 196 C CG . ASP A 1 29 ? 89.963 -20.276 26.632 1.00 44.50 ? 219 ASP A CG 1 ATOM 197 O OD1 . ASP A 1 29 ? 90.330 -19.890 27.765 1.00 49.36 ? 219 ASP A OD1 1 ATOM 198 O OD2 . ASP A 1 29 ? 90.744 -20.388 25.662 1.00 51.46 ? 219 ASP A OD2 1 ATOM 199 N N . LYS A 1 30 ? 87.922 -18.238 24.463 1.00 21.10 ? 220 LYS A N 1 ATOM 200 C CA . LYS A 1 30 ? 88.406 -17.190 23.578 1.00 16.60 ? 220 LYS A CA 1 ATOM 201 C C . LYS A 1 30 ? 87.670 -15.896 23.907 1.00 18.35 ? 220 LYS A C 1 ATOM 202 O O . LYS A 1 30 ? 88.269 -14.820 23.950 1.00 19.71 ? 220 LYS A O 1 ATOM 203 C CB . LYS A 1 30 ? 88.148 -17.572 22.119 1.00 16.07 ? 220 LYS A CB 1 ATOM 204 C CG . LYS A 1 30 ? 89.203 -17.062 21.160 1.00 23.13 ? 220 LYS A CG 1 ATOM 205 C CD . LYS A 1 30 ? 88.732 -17.107 19.721 1.00 25.18 ? 220 LYS A CD 1 ATOM 206 C CE . LYS A 1 30 ? 87.671 -16.051 19.468 1.00 30.57 ? 220 LYS A CE 1 ATOM 207 N NZ . LYS A 1 30 ? 87.323 -15.952 18.020 1.00 35.99 ? 220 LYS A NZ 1 ATOM 208 N N . ILE A 1 31 ? 86.366 -16.010 24.141 1.00 13.96 ? 221 ILE A N 1 ATOM 209 C CA . ILE A 1 31 ? 85.544 -14.857 24.476 1.00 14.76 ? 221 ILE A CA 1 ATOM 210 C C . ILE A 1 31 ? 86.010 -14.208 25.774 1.00 17.79 ? 221 ILE A C 1 ATOM 211 O O . ILE A 1 31 ? 86.193 -12.992 25.839 1.00 20.96 ? 221 ILE A O 1 ATOM 212 C CB . ILE A 1 31 ? 84.054 -15.253 24.622 1.00 15.67 ? 221 ILE A CB 1 ATOM 213 C CG1 . ILE A 1 31 ? 83.482 -15.626 23.251 1.00 13.67 ? 221 ILE A CG1 1 ATOM 214 C CG2 . ILE A 1 31 ? 83.261 -14.112 25.256 1.00 8.59 ? 221 ILE A CG2 1 ATOM 215 C CD1 . ILE A 1 31 ? 81.989 -15.921 23.261 1.00 14.35 ? 221 ILE A CD1 1 ATOM 216 N N . LYS A 1 32 ? 86.203 -15.023 26.805 1.00 16.89 ? 222 LYS A N 1 ATOM 217 C CA . LYS A 1 32 ? 86.639 -14.515 28.099 1.00 15.71 ? 222 LYS A CA 1 ATOM 218 C C . LYS A 1 32 ? 87.999 -13.838 28.008 1.00 17.35 ? 222 LYS A C 1 ATOM 219 O O . LYS A 1 32 ? 88.194 -12.735 28.525 1.00 13.94 ? 222 LYS A O 1 ATOM 220 C CB . LYS A 1 32 ? 86.704 -15.650 29.116 1.00 14.78 ? 222 LYS A CB 1 ATOM 221 C CG . LYS A 1 32 ? 85.402 -16.402 29.281 1.00 15.17 ? 222 LYS A CG 1 ATOM 222 C CD . LYS A 1 32 ? 85.544 -17.503 30.317 1.00 14.69 ? 222 LYS A CD 1 ATOM 223 C CE . LYS A 1 32 ? 84.299 -18.356 30.386 1.00 13.51 ? 222 LYS A CE 1 ATOM 224 N NZ . LYS A 1 32 ? 84.423 -19.367 31.464 1.00 25.76 ? 222 LYS A NZ 1 ATOM 225 N N . THR A 1 33 ? 88.939 -14.503 27.350 1.00 17.83 ? 223 THR A N 1 ATOM 226 C CA . THR A 1 33 ? 90.278 -13.951 27.204 1.00 20.89 ? 223 THR A CA 1 ATOM 227 C C . THR A 1 33 ? 90.218 -12.578 26.552 1.00 16.73 ? 223 THR A C 1 ATOM 228 O O . THR A 1 33 ? 90.867 -11.641 27.006 1.00 15.11 ? 223 THR A O 1 ATOM 229 C CB . THR A 1 33 ? 91.172 -14.869 26.353 1.00 21.95 ? 223 THR A CB 1 ATOM 230 O OG1 . THR A 1 33 ? 91.298 -16.139 27.002 1.00 30.85 ? 223 THR A OG1 1 ATOM 231 C CG2 . THR A 1 33 ? 92.552 -14.258 26.182 1.00 12.89 ? 223 THR A CG2 1 ATOM 232 N N . ARG A 1 34 ? 89.428 -12.463 25.490 1.00 16.49 ? 224 ARG A N 1 ATOM 233 C CA . ARG A 1 34 ? 89.298 -11.199 24.784 1.00 16.59 ? 224 ARG A CA 1 ATOM 234 C C . ARG A 1 34 ? 88.638 -10.127 25.655 1.00 18.89 ? 224 ARG A C 1 ATOM 235 O O . ARG A 1 34 ? 89.075 -8.978 25.666 1.00 18.09 ? 224 ARG A O 1 ATOM 236 C CB . ARG A 1 34 ? 88.491 -11.385 23.498 1.00 17.68 ? 224 ARG A CB 1 ATOM 237 C CG . ARG A 1 34 ? 88.620 -10.204 22.561 1.00 17.38 ? 224 ARG A CG 1 ATOM 238 C CD . ARG A 1 34 ? 87.700 -10.279 21.360 1.00 13.28 ? 224 ARG A CD 1 ATOM 239 N NE . ARG A 1 34 ? 87.856 -9.080 20.540 1.00 16.73 ? 224 ARG A NE 1 ATOM 240 C CZ . ARG A 1 34 ? 86.964 -8.648 19.657 1.00 13.69 ? 224 ARG A CZ 1 ATOM 241 N NH1 . ARG A 1 34 ? 85.837 -9.316 19.467 1.00 20.20 ? 224 ARG A NH1 1 ATOM 242 N NH2 . ARG A 1 34 ? 87.198 -7.538 18.973 1.00 18.91 ? 224 ARG A NH2 1 ATOM 243 N N . MET A 1 35 ? 87.586 -10.502 26.379 1.00 17.20 ? 225 MET A N 1 ATOM 244 C CA . MET A 1 35 ? 86.891 -9.559 27.249 1.00 14.63 ? 225 MET A CA 1 ATOM 245 C C . MET A 1 35 ? 87.847 -8.999 28.289 1.00 13.29 ? 225 MET A C 1 ATOM 246 O O . MET A 1 35 ? 87.796 -7.814 28.611 1.00 15.49 ? 225 MET A O 1 ATOM 247 C CB . MET A 1 35 ? 85.720 -10.232 27.966 1.00 13.58 ? 225 MET A CB 1 ATOM 248 C CG . MET A 1 35 ? 84.622 -10.725 27.050 1.00 20.15 ? 225 MET A CG 1 ATOM 249 S SD . MET A 1 35 ? 83.994 -9.437 25.965 1.00 18.23 ? 225 MET A SD 1 ATOM 250 C CE . MET A 1 35 ? 84.569 -10.052 24.402 1.00 24.38 ? 225 MET A CE 1 ATOM 251 N N . TYR A 1 36 ? 88.714 -9.856 28.817 1.00 11.84 ? 226 TYR A N 1 ATOM 252 C CA . TYR A 1 36 ? 89.679 -9.424 29.823 1.00 13.65 ? 226 TYR A CA 1 ATOM 253 C C . TYR A 1 36 ? 90.578 -8.336 29.253 1.00 14.22 ? 226 TYR A C 1 ATOM 254 O O . TYR A 1 36 ? 90.782 -7.296 29.877 1.00 16.03 ? 226 TYR A O 1 ATOM 255 C CB . TYR A 1 36 ? 90.544 -10.598 30.280 1.00 8.42 ? 226 TYR A CB 1 ATOM 256 C CG . TYR A 1 36 ? 89.777 -11.746 30.892 1.00 18.05 ? 226 TYR A CG 1 ATOM 257 C CD1 . TYR A 1 36 ? 90.351 -13.014 30.979 1.00 16.36 ? 226 TYR A CD1 1 ATOM 258 C CD2 . TYR A 1 36 ? 88.474 -11.579 31.364 1.00 12.39 ? 226 TYR A CD2 1 ATOM 259 C CE1 . TYR A 1 36 ? 89.650 -14.086 31.512 1.00 13.82 ? 226 TYR A CE1 1 ATOM 260 C CE2 . TYR A 1 36 ? 87.765 -12.649 31.902 1.00 13.84 ? 226 TYR A CE2 1 ATOM 261 C CZ . TYR A 1 36 ? 88.361 -13.902 31.969 1.00 15.07 ? 226 TYR A CZ 1 ATOM 262 O OH . TYR A 1 36 ? 87.669 -14.981 32.471 1.00 15.49 ? 226 TYR A OH 1 ATOM 263 N N . GLU A 1 37 ? 91.108 -8.576 28.060 1.00 15.61 ? 227 GLU A N 1 ATOM 264 C CA . GLU A 1 37 ? 91.989 -7.609 27.427 1.00 23.10 ? 227 GLU A CA 1 ATOM 265 C C . GLU A 1 37 ? 91.292 -6.286 27.142 1.00 20.22 ? 227 GLU A C 1 ATOM 266 O O . GLU A 1 37 ? 91.860 -5.216 27.358 1.00 21.26 ? 227 GLU A O 1 ATOM 267 C CB . GLU A 1 37 ? 92.551 -8.168 26.121 1.00 29.93 ? 227 GLU A CB 1 ATOM 268 C CG . GLU A 1 37 ? 93.514 -7.206 25.441 1.00 48.32 ? 227 GLU A CG 1 ATOM 269 C CD . GLU A 1 37 ? 94.037 -7.730 24.123 1.00 57.38 ? 227 GLU A CD 1 ATOM 270 O OE1 . GLU A 1 37 ? 94.583 -8.855 24.109 1.00 63.57 ? 227 GLU A OE1 1 ATOM 271 O OE2 . GLU A 1 37 ? 93.906 -7.014 23.106 1.00 57.07 ? 227 GLU A OE2 1 ATOM 272 N N . ILE A 1 38 ? 90.060 -6.364 26.653 1.00 15.15 ? 228 ILE A N 1 ATOM 273 C CA . ILE A 1 38 ? 89.300 -5.171 26.322 1.00 12.34 ? 228 ILE A CA 1 ATOM 274 C C . ILE A 1 38 ? 89.055 -4.296 27.547 1.00 9.81 ? 228 ILE A C 1 ATOM 275 O O . ILE A 1 38 ? 89.288 -3.089 27.507 1.00 2.40 ? 228 ILE A O 1 ATOM 276 C CB . ILE A 1 38 ? 87.959 -5.554 25.644 1.00 14.15 ? 228 ILE A CB 1 ATOM 277 C CG1 . ILE A 1 38 ? 88.253 -6.183 24.277 1.00 5.56 ? 228 ILE A CG1 1 ATOM 278 C CG2 . ILE A 1 38 ? 87.059 -4.329 25.494 1.00 7.48 ? 228 ILE A CG2 1 ATOM 279 C CD1 . ILE A 1 38 ? 87.021 -6.663 23.544 1.00 9.47 ? 228 ILE A CD1 1 ATOM 280 N N . VAL A 1 39 ? 88.596 -4.903 28.636 1.00 14.64 ? 229 VAL A N 1 ATOM 281 C CA . VAL A 1 39 ? 88.339 -4.153 29.861 1.00 14.97 ? 229 VAL A CA 1 ATOM 282 C C . VAL A 1 39 ? 89.652 -3.598 30.417 1.00 16.00 ? 229 VAL A C 1 ATOM 283 O O . VAL A 1 39 ? 89.658 -2.589 31.121 1.00 16.53 ? 229 VAL A O 1 ATOM 284 C CB . VAL A 1 39 ? 87.669 -5.039 30.934 1.00 17.56 ? 229 VAL A CB 1 ATOM 285 C CG1 . VAL A 1 39 ? 87.348 -4.208 32.171 1.00 17.58 ? 229 VAL A CG1 1 ATOM 286 C CG2 . VAL A 1 39 ? 86.402 -5.663 30.373 1.00 13.95 ? 229 VAL A CG2 1 ATOM 287 N N . ASN A 1 40 ? 90.763 -4.259 30.096 1.00 13.67 ? 230 ASN A N 1 ATOM 288 C CA . ASN A 1 40 ? 92.074 -3.807 30.553 1.00 12.96 ? 230 ASN A CA 1 ATOM 289 C C . ASN A 1 40 ? 92.482 -2.550 29.795 1.00 15.86 ? 230 ASN A C 1 ATOM 290 O O . ASN A 1 40 ? 93.172 -1.683 30.335 1.00 19.67 ? 230 ASN A O 1 ATOM 291 C CB . ASN A 1 40 ? 93.120 -4.907 30.356 1.00 19.15 ? 230 ASN A CB 1 ATOM 292 C CG . ASN A 1 40 ? 94.546 -4.391 30.473 1.00 23.95 ? 230 ASN A CG 1 ATOM 293 O OD1 . ASN A 1 40 ? 95.118 -3.876 29.507 1.00 21.49 ? 230 ASN A OD1 1 ATOM 294 N ND2 . ASN A 1 40 ? 95.124 -4.518 31.662 1.00 27.40 ? 230 ASN A ND2 1 ATOM 295 N N . THR A 1 41 ? 92.049 -2.452 28.543 1.00 16.53 ? 231 THR A N 1 ATOM 296 C CA . THR A 1 41 ? 92.354 -1.287 27.724 1.00 15.15 ? 231 THR A CA 1 ATOM 297 C C . THR A 1 41 ? 91.407 -0.145 28.101 1.00 16.23 ? 231 THR A C 1 ATOM 298 O O . THR A 1 41 ? 91.794 1.027 28.072 1.00 14.44 ? 231 THR A O 1 ATOM 299 C CB . THR A 1 41 ? 92.208 -1.605 26.231 1.00 16.99 ? 231 THR A CB 1 ATOM 300 O OG1 . THR A 1 41 ? 93.076 -2.692 25.889 1.00 16.09 ? 231 THR A OG1 1 ATOM 301 C CG2 . THR A 1 41 ? 92.580 -0.400 25.395 1.00 22.06 ? 231 THR A CG2 1 ATOM 302 N N . VAL A 1 42 ? 90.169 -0.488 28.457 1.00 8.50 ? 232 VAL A N 1 ATOM 303 C CA . VAL A 1 42 ? 89.198 0.518 28.871 1.00 11.98 ? 232 VAL A CA 1 ATOM 304 C C . VAL A 1 42 ? 89.741 1.187 30.131 1.00 19.94 ? 232 VAL A C 1 ATOM 305 O O . VAL A 1 42 ? 89.612 2.398 30.310 1.00 25.40 ? 232 VAL A O 1 ATOM 306 C CB . VAL A 1 42 ? 87.811 -0.110 29.200 1.00 13.66 ? 232 VAL A CB 1 ATOM 307 C CG1 . VAL A 1 42 ? 86.928 0.906 29.922 1.00 1.27 ? 232 VAL A CG1 1 ATOM 308 C CG2 . VAL A 1 42 ? 87.128 -0.571 27.922 1.00 10.62 ? 232 VAL A CG2 1 ATOM 309 N N . ASN A 1 43 ? 90.357 0.390 30.999 1.00 20.68 ? 233 ASN A N 1 ATOM 310 C CA . ASN A 1 43 ? 90.919 0.909 32.239 1.00 19.58 ? 233 ASN A CA 1 ATOM 311 C C . ASN A 1 43 ? 92.058 1.896 31.973 1.00 18.46 ? 233 ASN A C 1 ATOM 312 O O . ASN A 1 43 ? 92.214 2.877 32.699 1.00 22.21 ? 233 ASN A O 1 ATOM 313 C CB . ASN A 1 43 ? 91.420 -0.241 33.120 1.00 18.46 ? 233 ASN A CB 1 ATOM 314 C CG . ASN A 1 43 ? 91.875 0.230 34.491 1.00 17.41 ? 233 ASN A CG 1 ATOM 315 O OD1 . ASN A 1 43 ? 91.099 0.805 35.252 1.00 13.33 ? 233 ASN A OD1 1 ATOM 316 N ND2 . ASN A 1 43 ? 93.141 -0.009 34.808 1.00 17.68 ? 233 ASN A ND2 1 ATOM 317 N N . GLU A 1 44 ? 92.852 1.639 30.937 1.00 17.44 ? 234 GLU A N 1 ATOM 318 C CA . GLU A 1 44 ? 93.960 2.531 30.597 1.00 16.65 ? 234 GLU A CA 1 ATOM 319 C C . GLU A 1 44 ? 93.365 3.848 30.106 1.00 13.08 ? 234 GLU A C 1 ATOM 320 O O . GLU A 1 44 ? 93.725 4.926 30.574 1.00 9.62 ? 234 GLU A O 1 ATOM 321 C CB . GLU A 1 44 ? 94.832 1.922 29.489 1.00 19.06 ? 234 GLU A CB 1 ATOM 322 C CG . GLU A 1 44 ? 95.284 0.489 29.747 1.00 33.71 ? 234 GLU A CG 1 ATOM 323 C CD . GLU A 1 44 ? 96.144 -0.079 28.622 1.00 41.47 ? 234 GLU A CD 1 ATOM 324 O OE1 . GLU A 1 44 ? 95.727 0.001 27.444 1.00 45.68 ? 234 GLU A OE1 1 ATOM 325 O OE2 . GLU A 1 44 ? 97.235 -0.614 28.917 1.00 43.98 ? 234 GLU A OE2 1 ATOM 326 N N . ILE A 1 45 ? 92.440 3.737 29.160 1.00 10.79 ? 235 ILE A N 1 ATOM 327 C CA . ILE A 1 45 ? 91.769 4.889 28.581 1.00 11.16 ? 235 ILE A CA 1 ATOM 328 C C . ILE A 1 45 ? 91.201 5.830 29.645 1.00 12.57 ? 235 ILE A C 1 ATOM 329 O O . ILE A 1 45 ? 91.117 7.043 29.433 1.00 15.16 ? 235 ILE A O 1 ATOM 330 C CB . ILE A 1 45 ? 90.628 4.425 27.640 1.00 8.80 ? 235 ILE A CB 1 ATOM 331 C CG1 . ILE A 1 45 ? 91.228 3.683 26.441 1.00 10.94 ? 235 ILE A CG1 1 ATOM 332 C CG2 . ILE A 1 45 ? 89.801 5.611 27.181 1.00 9.69 ? 235 ILE A CG2 1 ATOM 333 C CD1 . ILE A 1 45 ? 90.211 3.146 25.461 1.00 4.54 ? 235 ILE A CD1 1 ATOM 334 N N . TYR A 1 46 ? 90.826 5.272 30.791 1.00 7.22 ? 236 TYR A N 1 ATOM 335 C CA . TYR A 1 46 ? 90.252 6.063 31.871 1.00 9.74 ? 236 TYR A CA 1 ATOM 336 C C . TYR A 1 46 ? 91.253 6.556 32.911 1.00 13.74 ? 236 TYR A C 1 ATOM 337 O O . TYR A 1 46 ? 90.882 7.284 33.839 1.00 16.46 ? 236 TYR A O 1 ATOM 338 C CB . TYR A 1 46 ? 89.149 5.264 32.561 1.00 7.43 ? 236 TYR A CB 1 ATOM 339 C CG . TYR A 1 46 ? 87.782 5.486 31.973 1.00 2.13 ? 236 TYR A CG 1 ATOM 340 C CD1 . TYR A 1 46 ? 87.016 6.590 32.345 1.00 12.12 ? 236 TYR A CD1 1 ATOM 341 C CD2 . TYR A 1 46 ? 87.251 4.598 31.041 1.00 7.79 ? 236 TYR A CD2 1 ATOM 342 C CE1 . TYR A 1 46 ? 85.748 6.804 31.803 1.00 16.12 ? 236 TYR A CE1 1 ATOM 343 C CE2 . TYR A 1 46 ? 85.986 4.799 30.490 1.00 5.79 ? 236 TYR A CE2 1 ATOM 344 C CZ . TYR A 1 46 ? 85.240 5.903 30.875 1.00 13.28 ? 236 TYR A CZ 1 ATOM 345 O OH . TYR A 1 46 ? 83.992 6.106 30.332 1.00 11.92 ? 236 TYR A OH 1 ATOM 346 N N . ARG A 1 47 ? 92.513 6.160 32.764 1.00 9.06 ? 237 ARG A N 1 ATOM 347 C CA . ARG A 1 47 ? 93.545 6.586 33.700 1.00 12.69 ? 237 ARG A CA 1 ATOM 348 C C . ARG A 1 47 ? 93.563 8.111 33.739 1.00 17.34 ? 237 ARG A C 1 ATOM 349 O O . ARG A 1 47 ? 93.654 8.721 34.805 1.00 21.33 ? 237 ARG A O 1 ATOM 350 C CB . ARG A 1 47 ? 94.909 6.051 33.254 1.00 16.65 ? 237 ARG A CB 1 ATOM 351 C CG . ARG A 1 47 ? 96.067 6.429 34.162 1.00 19.99 ? 237 ARG A CG 1 ATOM 352 C CD . ARG A 1 47 ? 97.342 5.716 33.740 1.00 22.59 ? 237 ARG A CD 1 ATOM 353 N NE . ARG A 1 47 ? 98.460 6.014 34.632 1.00 31.77 ? 237 ARG A NE 1 ATOM 354 C CZ . ARG A 1 47 ? 99.105 7.176 34.670 1.00 33.29 ? 237 ARG A CZ 1 ATOM 355 N NH1 . ARG A 1 47 ? 98.749 8.161 33.859 1.00 33.77 ? 237 ARG A NH1 1 ATOM 356 N NH2 . ARG A 1 47 ? 100.104 7.356 35.524 1.00 33.16 ? 237 ARG A NH2 1 ATOM 357 N N . TYR A 1 48 ? 93.463 8.714 32.559 1.00 19.54 ? 238 TYR A N 1 ATOM 358 C CA . TYR A 1 48 ? 93.460 10.164 32.405 1.00 20.20 ? 238 TYR A CA 1 ATOM 359 C C . TYR A 1 48 ? 92.347 10.813 33.214 1.00 21.63 ? 238 TYR A C 1 ATOM 360 O O . TYR A 1 48 ? 92.545 11.865 33.810 1.00 28.10 ? 238 TYR A O 1 ATOM 361 C CB . TYR A 1 48 ? 93.284 10.512 30.927 1.00 26.65 ? 238 TYR A CB 1 ATOM 362 C CG . TYR A 1 48 ? 93.056 11.976 30.636 1.00 31.25 ? 238 TYR A CG 1 ATOM 363 C CD1 . TYR A 1 48 ? 94.090 12.902 30.759 1.00 33.58 ? 238 TYR A CD1 1 ATOM 364 C CD2 . TYR A 1 48 ? 91.806 12.434 30.213 1.00 33.09 ? 238 TYR A CD2 1 ATOM 365 C CE1 . TYR A 1 48 ? 93.890 14.251 30.462 1.00 34.64 ? 238 TYR A CE1 1 ATOM 366 C CE2 . TYR A 1 48 ? 91.592 13.780 29.915 1.00 35.36 ? 238 TYR A CE2 1 ATOM 367 C CZ . TYR A 1 48 ? 92.639 14.682 30.040 1.00 37.12 ? 238 TYR A CZ 1 ATOM 368 O OH . TYR A 1 48 ? 92.442 16.010 29.735 1.00 34.89 ? 238 TYR A OH 1 ATOM 369 N N . MET A 1 49 ? 91.178 10.176 33.226 1.00 22.29 ? 239 MET A N 1 ATOM 370 C CA . MET A 1 49 ? 90.006 10.683 33.945 1.00 20.09 ? 239 MET A CA 1 ATOM 371 C C . MET A 1 49 ? 90.057 10.369 35.437 1.00 21.59 ? 239 MET A C 1 ATOM 372 O O . MET A 1 49 ? 89.052 10.508 36.138 1.00 15.94 ? 239 MET A O 1 ATOM 373 C CB . MET A 1 49 ? 88.733 10.060 33.368 1.00 20.67 ? 239 MET A CB 1 ATOM 374 C CG . MET A 1 49 ? 88.592 10.170 31.862 1.00 22.07 ? 239 MET A CG 1 ATOM 375 S SD . MET A 1 49 ? 88.105 11.801 31.314 1.00 22.69 ? 239 MET A SD 1 ATOM 376 C CE . MET A 1 49 ? 86.342 11.607 31.185 1.00 18.03 ? 239 MET A CE 1 ATOM 377 N N . TYR A 1 50 ? 91.222 9.945 35.917 1.00 22.48 ? 240 TYR A N 1 ATOM 378 C CA . TYR A 1 50 ? 91.384 9.589 37.323 1.00 22.63 ? 240 TYR A CA 1 ATOM 379 C C . TYR A 1 50 ? 90.340 8.565 37.751 1.00 22.75 ? 240 TYR A C 1 ATOM 380 O O . TYR A 1 50 ? 89.838 8.597 38.877 1.00 23.62 ? 240 TYR A O 1 ATOM 381 C CB . TYR A 1 50 ? 91.300 10.831 38.220 1.00 24.00 ? 240 TYR A CB 1 ATOM 382 C CG . TYR A 1 50 ? 92.565 11.658 38.206 1.00 29.52 ? 240 TYR A CG 1 ATOM 383 C CD1 . TYR A 1 50 ? 92.703 12.746 37.344 1.00 29.40 ? 240 TYR A CD1 1 ATOM 384 C CD2 . TYR A 1 50 ? 93.649 11.318 39.020 1.00 31.16 ? 240 TYR A CD2 1 ATOM 385 C CE1 . TYR A 1 50 ? 93.893 13.475 37.290 1.00 34.27 ? 240 TYR A CE1 1 ATOM 386 C CE2 . TYR A 1 50 ? 94.843 12.036 38.975 1.00 29.97 ? 240 TYR A CE2 1 ATOM 387 C CZ . TYR A 1 50 ? 94.960 13.113 38.107 1.00 36.15 ? 240 TYR A CZ 1 ATOM 388 O OH . TYR A 1 50 ? 96.143 13.823 38.050 1.00 33.07 ? 240 TYR A OH 1 ATOM 389 N N . ILE A 1 51 ? 90.024 7.650 36.839 1.00 19.92 ? 241 ILE A N 1 ATOM 390 C CA . ILE A 1 51 ? 89.050 6.601 37.112 1.00 15.00 ? 241 ILE A CA 1 ATOM 391 C C . ILE A 1 51 ? 89.631 5.242 36.734 1.00 12.20 ? 241 ILE A C 1 ATOM 392 O O . ILE A 1 51 ? 90.402 5.127 35.783 1.00 9.35 ? 241 ILE A O 1 ATOM 393 C CB . ILE A 1 51 ? 87.741 6.814 36.307 1.00 14.33 ? 241 ILE A CB 1 ATOM 394 C CG1 . ILE A 1 51 ? 87.094 8.142 36.700 1.00 11.43 ? 241 ILE A CG1 1 ATOM 395 C CG2 . ILE A 1 51 ? 86.771 5.660 36.558 1.00 7.60 ? 241 ILE A CG2 1 ATOM 396 C CD1 . ILE A 1 51 ? 85.773 8.416 35.988 1.00 6.47 ? 241 ILE A CD1 1 ATOM 397 N N . HIS A 1 52 ? 89.269 4.221 37.499 1.00 10.81 ? 242 HIS A N 1 ATOM 398 C CA . HIS A 1 52 ? 89.721 2.864 37.233 1.00 7.76 ? 242 HIS A CA 1 ATOM 399 C C . HIS A 1 52 ? 88.490 2.034 36.912 1.00 11.45 ? 242 HIS A C 1 ATOM 400 O O . HIS A 1 52 ? 87.394 2.316 37.403 1.00 13.13 ? 242 HIS A O 1 ATOM 401 C CB . HIS A 1 52 ? 90.426 2.269 38.451 1.00 7.85 ? 242 HIS A CB 1 ATOM 402 C CG . HIS A 1 52 ? 91.789 2.836 38.703 1.00 16.67 ? 242 HIS A CG 1 ATOM 403 N ND1 . HIS A 1 52 ? 92.764 2.891 37.731 1.00 17.62 ? 242 HIS A ND1 1 ATOM 404 C CD2 . HIS A 1 52 ? 92.351 3.341 39.827 1.00 14.33 ? 242 HIS A CD2 1 ATOM 405 C CE1 . HIS A 1 52 ? 93.868 3.404 38.244 1.00 17.23 ? 242 HIS A CE1 1 ATOM 406 N NE2 . HIS A 1 52 ? 93.644 3.686 39.514 1.00 18.10 ? 242 HIS A NE2 1 ATOM 407 N N . VAL A 1 53 ? 88.670 1.017 36.078 1.00 12.54 ? 243 VAL A N 1 ATOM 408 C CA . VAL A 1 53 ? 87.575 0.135 35.703 1.00 11.90 ? 243 VAL A CA 1 ATOM 409 C C . VAL A 1 53 ? 88.007 -1.307 35.946 1.00 13.31 ? 243 VAL A C 1 ATOM 410 O O . VAL A 1 53 ? 89.000 -1.773 35.379 1.00 10.73 ? 243 VAL A O 1 ATOM 411 C CB . VAL A 1 53 ? 87.193 0.317 34.222 1.00 13.33 ? 243 VAL A CB 1 ATOM 412 C CG1 . VAL A 1 53 ? 86.047 -0.618 33.865 1.00 11.35 ? 243 VAL A CG1 1 ATOM 413 C CG2 . VAL A 1 53 ? 86.796 1.767 33.965 1.00 6.71 ? 243 VAL A CG2 1 ATOM 414 N N . ALA A 1 54 ? 87.267 -2.006 36.799 1.00 10.49 ? 244 ALA A N 1 ATOM 415 C CA . ALA A 1 54 ? 87.596 -3.385 37.120 1.00 10.88 ? 244 ALA A CA 1 ATOM 416 C C . ALA A 1 54 ? 86.453 -4.323 36.770 1.00 13.60 ? 244 ALA A C 1 ATOM 417 O O . ALA A 1 54 ? 85.290 -4.024 37.040 1.00 16.89 ? 244 ALA A O 1 ATOM 418 C CB . ALA A 1 54 ? 87.938 -3.499 38.596 1.00 11.64 ? 244 ALA A CB 1 ATOM 419 N N . LEU A 1 55 ? 86.786 -5.458 36.166 1.00 17.35 ? 245 LEU A N 1 ATOM 420 C CA . LEU A 1 55 ? 85.777 -6.438 35.782 1.00 18.09 ? 245 LEU A CA 1 ATOM 421 C C . LEU A 1 55 ? 85.448 -7.320 36.982 1.00 17.55 ? 245 LEU A C 1 ATOM 422 O O . LEU A 1 55 ? 86.244 -8.183 37.361 1.00 17.97 ? 245 LEU A O 1 ATOM 423 C CB . LEU A 1 55 ? 86.294 -7.300 34.622 1.00 16.46 ? 245 LEU A CB 1 ATOM 424 C CG . LEU A 1 55 ? 85.321 -8.307 33.997 1.00 19.10 ? 245 LEU A CG 1 ATOM 425 C CD1 . LEU A 1 55 ? 84.171 -7.568 33.322 1.00 18.21 ? 245 LEU A CD1 1 ATOM 426 C CD2 . LEU A 1 55 ? 86.060 -9.172 32.984 1.00 14.64 ? 245 LEU A CD2 1 ATOM 427 N N . VAL A 1 56 ? 84.280 -7.101 37.582 1.00 13.04 ? 246 VAL A N 1 ATOM 428 C CA . VAL A 1 56 ? 83.866 -7.884 38.741 1.00 10.45 ? 246 VAL A CA 1 ATOM 429 C C . VAL A 1 56 ? 82.927 -9.030 38.370 1.00 17.55 ? 246 VAL A C 1 ATOM 430 O O . VAL A 1 56 ? 82.571 -9.850 39.219 1.00 19.81 ? 246 VAL A O 1 ATOM 431 C CB . VAL A 1 56 ? 83.155 -7.008 39.782 1.00 8.34 ? 246 VAL A CB 1 ATOM 432 C CG1 . VAL A 1 56 ? 84.052 -5.853 40.184 1.00 13.48 ? 246 VAL A CG1 1 ATOM 433 C CG2 . VAL A 1 56 ? 81.829 -6.509 39.229 1.00 8.46 ? 246 VAL A CG2 1 ATOM 434 N N . GLY A 1 57 ? 82.524 -9.083 37.104 1.00 16.55 ? 247 GLY A N 1 ATOM 435 C CA . GLY A 1 57 ? 81.627 -10.136 36.669 1.00 13.65 ? 247 GLY A CA 1 ATOM 436 C C . GLY A 1 57 ? 81.553 -10.265 35.162 1.00 14.23 ? 247 GLY A C 1 ATOM 437 O O . GLY A 1 57 ? 81.636 -9.276 34.437 1.00 15.29 ? 247 GLY A O 1 ATOM 438 N N . LEU A 1 58 ? 81.406 -11.497 34.689 1.00 10.57 ? 248 LEU A N 1 ATOM 439 C CA . LEU A 1 58 ? 81.316 -11.763 33.264 1.00 12.94 ? 248 LEU A CA 1 ATOM 440 C C . LEU A 1 58 ? 80.286 -12.858 33.023 1.00 18.86 ? 248 LEU A C 1 ATOM 441 O O . LEU A 1 58 ? 80.500 -14.015 33.389 1.00 25.99 ? 248 LEU A O 1 ATOM 442 C CB . LEU A 1 58 ? 82.678 -12.197 32.722 1.00 6.70 ? 248 LEU A CB 1 ATOM 443 C CG . LEU A 1 58 ? 82.761 -12.436 31.212 1.00 12.50 ? 248 LEU A CG 1 ATOM 444 C CD1 . LEU A 1 58 ? 82.274 -11.204 30.465 1.00 13.51 ? 248 LEU A CD1 1 ATOM 445 C CD2 . LEU A 1 58 ? 84.197 -12.769 30.826 1.00 13.76 ? 248 LEU A CD2 1 ATOM 446 N N . GLU A 1 59 ? 79.169 -12.487 32.409 1.00 15.98 ? 249 GLU A N 1 ATOM 447 C CA . GLU A 1 59 ? 78.101 -13.436 32.128 1.00 20.25 ? 249 GLU A CA 1 ATOM 448 C C . GLU A 1 59 ? 77.959 -13.670 30.624 1.00 21.22 ? 249 GLU A C 1 ATOM 449 O O . GLU A 1 59 ? 77.768 -12.725 29.858 1.00 21.81 ? 249 GLU A O 1 ATOM 450 C CB . GLU A 1 59 ? 76.792 -12.912 32.729 1.00 22.99 ? 249 GLU A CB 1 ATOM 451 C CG . GLU A 1 59 ? 75.573 -13.788 32.499 1.00 23.35 ? 249 GLU A CG 1 ATOM 452 C CD . GLU A 1 59 ? 74.518 -13.601 33.575 1.00 23.40 ? 249 GLU A CD 1 ATOM 453 O OE1 . GLU A 1 59 ? 73.356 -13.992 33.348 1.00 28.95 ? 249 GLU A OE1 1 ATOM 454 O OE2 . GLU A 1 59 ? 74.851 -13.074 34.656 1.00 28.32 ? 249 GLU A OE2 1 ATOM 455 N N . ILE A 1 60 ? 78.065 -14.932 30.210 1.00 20.99 ? 250 ILE A N 1 ATOM 456 C CA . ILE A 1 60 ? 77.964 -15.307 28.799 1.00 19.83 ? 250 ILE A CA 1 ATOM 457 C C . ILE A 1 60 ? 76.683 -16.092 28.551 1.00 21.59 ? 250 ILE A C 1 ATOM 458 O O . ILE A 1 60 ? 76.523 -17.188 29.082 1.00 26.06 ? 250 ILE A O 1 ATOM 459 C CB . ILE A 1 60 ? 79.141 -16.218 28.364 1.00 22.75 ? 250 ILE A CB 1 ATOM 460 C CG1 . ILE A 1 60 ? 80.487 -15.543 28.649 1.00 15.93 ? 250 ILE A CG1 1 ATOM 461 C CG2 . ILE A 1 60 ? 79.013 -16.559 26.885 1.00 18.40 ? 250 ILE A CG2 1 ATOM 462 C CD1 . ILE A 1 60 ? 80.780 -14.365 27.778 1.00 22.33 ? 250 ILE A CD1 1 ATOM 463 N N . TRP A 1 61 ? 75.781 -15.544 27.741 1.00 21.16 ? 251 TRP A N 1 ATOM 464 C CA . TRP A 1 61 ? 74.524 -16.225 27.429 1.00 20.26 ? 251 TRP A CA 1 ATOM 465 C C . TRP A 1 61 ? 74.714 -17.249 26.305 1.00 23.00 ? 251 TRP A C 1 ATOM 466 O O . TRP A 1 61 ? 74.154 -17.109 25.218 1.00 23.70 ? 251 TRP A O 1 ATOM 467 C CB . TRP A 1 61 ? 73.454 -15.211 27.015 1.00 24.08 ? 251 TRP A CB 1 ATOM 468 C CG . TRP A 1 61 ? 73.041 -14.253 28.097 1.00 22.79 ? 251 TRP A CG 1 ATOM 469 C CD1 . TRP A 1 61 ? 73.163 -14.432 29.446 1.00 20.45 ? 251 TRP A CD1 1 ATOM 470 C CD2 . TRP A 1 61 ? 72.382 -12.993 27.918 1.00 21.11 ? 251 TRP A CD2 1 ATOM 471 N NE1 . TRP A 1 61 ? 72.618 -13.362 30.118 1.00 19.87 ? 251 TRP A NE1 1 ATOM 472 C CE2 . TRP A 1 61 ? 72.129 -12.466 29.205 1.00 24.02 ? 251 TRP A CE2 1 ATOM 473 C CE3 . TRP A 1 61 ? 71.974 -12.260 26.795 1.00 21.97 ? 251 TRP A CE3 1 ATOM 474 C CZ2 . TRP A 1 61 ? 71.491 -11.233 29.399 1.00 28.90 ? 251 TRP A CZ2 1 ATOM 475 C CZ3 . TRP A 1 61 ? 71.340 -11.034 26.988 1.00 22.05 ? 251 TRP A CZ3 1 ATOM 476 C CH2 . TRP A 1 61 ? 71.103 -10.535 28.282 1.00 23.67 ? 251 TRP A CH2 1 ATOM 477 N N . SER A 1 62 ? 75.499 -18.285 26.574 1.00 25.87 ? 252 SER A N 1 ATOM 478 C CA . SER A 1 62 ? 75.771 -19.318 25.581 1.00 25.55 ? 252 SER A CA 1 ATOM 479 C C . SER A 1 62 ? 74.553 -20.158 25.206 1.00 25.60 ? 252 SER A C 1 ATOM 480 O O . SER A 1 62 ? 74.483 -20.685 24.096 1.00 28.30 ? 252 SER A O 1 ATOM 481 C CB . SER A 1 62 ? 76.897 -20.229 26.073 1.00 22.17 ? 252 SER A CB 1 ATOM 482 O OG . SER A 1 62 ? 76.622 -20.713 27.373 1.00 26.86 ? 252 SER A OG 1 ATOM 483 N N . ASN A 1 63 ? 73.598 -20.293 26.120 1.00 26.34 ? 253 ASN A N 1 ATOM 484 C CA . ASN A 1 63 ? 72.396 -21.071 25.829 1.00 28.78 ? 253 ASN A CA 1 ATOM 485 C C . ASN A 1 63 ? 71.314 -20.194 25.218 1.00 28.14 ? 253 ASN A C 1 ATOM 486 O O . ASN A 1 63 ? 70.980 -20.342 24.044 1.00 26.99 ? 253 ASN A O 1 ATOM 487 C CB . ASN A 1 63 ? 71.872 -21.745 27.095 1.00 35.29 ? 253 ASN A CB 1 ATOM 488 C CG . ASN A 1 63 ? 72.780 -22.862 27.569 1.00 51.21 ? 253 ASN A CG 1 ATOM 489 O OD1 . ASN A 1 63 ? 73.922 -22.623 27.964 1.00 58.81 ? 253 ASN A OD1 1 ATOM 490 N ND2 . ASN A 1 63 ? 72.281 -24.095 27.519 1.00 54.70 ? 253 ASN A ND2 1 ATOM 491 N N . GLU A 1 64 ? 70.770 -19.277 26.009 1.00 25.54 ? 254 GLU A N 1 ATOM 492 C CA . GLU A 1 64 ? 69.737 -18.377 25.513 1.00 27.03 ? 254 GLU A CA 1 ATOM 493 C C . GLU A 1 64 ? 69.889 -16.976 26.099 1.00 24.14 ? 254 GLU A C 1 ATOM 494 O O . GLU A 1 64 ? 70.346 -16.813 27.230 1.00 19.69 ? 254 GLU A O 1 ATOM 495 C CB . GLU A 1 64 ? 68.348 -18.932 25.843 1.00 28.98 ? 254 GLU A CB 1 ATOM 496 C CG . GLU A 1 64 ? 68.083 -19.121 27.329 1.00 44.14 ? 254 GLU A CG 1 ATOM 497 C CD . GLU A 1 64 ? 66.687 -19.659 27.609 1.00 51.54 ? 254 GLU A CD 1 ATOM 498 O OE1 . GLU A 1 64 ? 66.376 -20.775 27.144 1.00 57.25 ? 254 GLU A OE1 1 ATOM 499 O OE2 . GLU A 1 64 ? 65.900 -18.966 28.291 1.00 51.70 ? 254 GLU A OE2 1 ATOM 500 N N . ASP A 1 65 ? 69.523 -15.962 25.322 1.00 19.57 ? 255 ASP A N 1 ATOM 501 C CA . ASP A 1 65 ? 69.608 -14.595 25.808 1.00 22.63 ? 255 ASP A CA 1 ATOM 502 C C . ASP A 1 65 ? 68.526 -14.423 26.865 1.00 23.67 ? 255 ASP A C 1 ATOM 503 O O . ASP A 1 65 ? 67.419 -14.940 26.717 1.00 20.02 ? 255 ASP A O 1 ATOM 504 C CB . ASP A 1 65 ? 69.382 -13.587 24.677 1.00 24.58 ? 255 ASP A CB 1 ATOM 505 C CG . ASP A 1 65 ? 70.457 -13.653 23.603 1.00 24.11 ? 255 ASP A CG 1 ATOM 506 O OD1 . ASP A 1 65 ? 71.646 -13.822 23.946 1.00 23.30 ? 255 ASP A OD1 1 ATOM 507 O OD2 . ASP A 1 65 ? 70.110 -13.519 22.413 1.00 21.57 ? 255 ASP A OD2 1 ATOM 508 N N . LYS A 1 66 ? 68.848 -13.701 27.932 1.00 26.11 ? 256 LYS A N 1 ATOM 509 C CA . LYS A 1 66 ? 67.891 -13.482 29.005 1.00 24.97 ? 256 LYS A CA 1 ATOM 510 C C . LYS A 1 66 ? 66.906 -12.356 28.686 1.00 26.83 ? 256 LYS A C 1 ATOM 511 O O . LYS A 1 66 ? 65.964 -12.103 29.439 1.00 28.50 ? 256 LYS A O 1 ATOM 512 C CB . LYS A 1 66 ? 68.642 -13.238 30.314 1.00 26.68 ? 256 LYS A CB 1 ATOM 513 C CG . LYS A 1 66 ? 69.534 -14.426 30.671 1.00 28.61 ? 256 LYS A CG 1 ATOM 514 C CD . LYS A 1 66 ? 70.060 -14.382 32.091 1.00 33.37 ? 256 LYS A CD 1 ATOM 515 C CE . LYS A 1 66 ? 70.844 -15.651 32.403 1.00 33.65 ? 256 LYS A CE 1 ATOM 516 N NZ . LYS A 1 66 ? 71.328 -15.704 33.814 1.00 38.43 ? 256 LYS A NZ 1 ATOM 517 N N . ILE A 1 67 ? 67.136 -11.688 27.559 1.00 24.64 ? 257 ILE A N 1 ATOM 518 C CA . ILE A 1 67 ? 66.252 -10.632 27.068 1.00 21.23 ? 257 ILE A CA 1 ATOM 519 C C . ILE A 1 67 ? 66.229 -10.830 25.562 1.00 23.57 ? 257 ILE A C 1 ATOM 520 O O . ILE A 1 67 ? 67.022 -11.613 25.027 1.00 19.43 ? 257 ILE A O 1 ATOM 521 C CB . ILE A 1 67 ? 66.784 -9.200 27.331 1.00 18.24 ? 257 ILE A CB 1 ATOM 522 C CG1 . ILE A 1 67 ? 68.130 -9.009 26.636 1.00 14.13 ? 257 ILE A CG1 1 ATOM 523 C CG2 . ILE A 1 67 ? 66.871 -8.931 28.818 1.00 13.95 ? 257 ILE A CG2 1 ATOM 524 C CD1 . ILE A 1 67 ? 68.595 -7.570 26.597 1.00 15.87 ? 257 ILE A CD1 1 ATOM 525 N N . THR A 1 68 ? 65.328 -10.137 24.876 1.00 21.34 ? 258 THR A N 1 ATOM 526 C CA . THR A 1 68 ? 65.270 -10.253 23.426 1.00 23.91 ? 258 THR A CA 1 ATOM 527 C C . THR A 1 68 ? 66.205 -9.191 22.854 1.00 22.17 ? 258 THR A C 1 ATOM 528 O O . THR A 1 68 ? 65.952 -7.995 22.995 1.00 22.53 ? 258 THR A O 1 ATOM 529 C CB . THR A 1 68 ? 63.846 -10.016 22.895 1.00 28.86 ? 258 THR A CB 1 ATOM 530 O OG1 . THR A 1 68 ? 62.954 -10.972 23.478 1.00 33.17 ? 258 THR A OG1 1 ATOM 531 C CG2 . THR A 1 68 ? 63.814 -10.161 21.380 1.00 29.08 ? 258 THR A CG2 1 ATOM 532 N N . VAL A 1 69 ? 67.291 -9.623 22.222 1.00 16.99 ? 259 VAL A N 1 ATOM 533 C CA . VAL A 1 69 ? 68.243 -8.673 21.661 1.00 16.71 ? 259 VAL A CA 1 ATOM 534 C C . VAL A 1 69 ? 67.825 -8.248 20.265 1.00 17.92 ? 259 VAL A C 1 ATOM 535 O O . VAL A 1 69 ? 68.122 -8.932 19.284 1.00 11.77 ? 259 VAL A O 1 ATOM 536 C CB . VAL A 1 69 ? 69.665 -9.264 21.590 1.00 16.07 ? 259 VAL A CB 1 ATOM 537 C CG1 . VAL A 1 69 ? 70.647 -8.179 21.184 1.00 16.64 ? 259 VAL A CG1 1 ATOM 538 C CG2 . VAL A 1 69 ? 70.057 -9.852 22.934 1.00 16.08 ? 259 VAL A CG2 1 ATOM 539 N N . LYS A 1 70 ? 67.140 -7.111 20.181 1.00 17.72 ? 260 LYS A N 1 ATOM 540 C CA . LYS A 1 70 ? 66.672 -6.602 18.899 1.00 18.02 ? 260 LYS A CA 1 ATOM 541 C C . LYS A 1 70 ? 67.633 -5.583 18.314 1.00 15.52 ? 260 LYS A C 1 ATOM 542 O O . LYS A 1 70 ? 68.281 -4.840 19.050 1.00 10.49 ? 260 LYS A O 1 ATOM 543 C CB . LYS A 1 70 ? 65.293 -5.954 19.050 1.00 19.09 ? 260 LYS A CB 1 ATOM 544 C CG . LYS A 1 70 ? 64.200 -6.890 19.534 1.00 20.26 ? 260 LYS A CG 1 ATOM 545 C CD . LYS A 1 70 ? 62.867 -6.167 19.583 1.00 25.01 ? 260 LYS A CD 1 ATOM 546 C CE . LYS A 1 70 ? 61.784 -7.044 20.179 1.00 29.75 ? 260 LYS A CE 1 ATOM 547 N NZ . LYS A 1 70 ? 60.510 -6.300 20.361 1.00 32.82 ? 260 LYS A NZ 1 ATOM 548 N N . PRO A 1 71 ? 67.744 -5.544 16.975 1.00 16.75 ? 261 PRO A N 1 ATOM 549 C CA . PRO A 1 71 ? 68.642 -4.591 16.315 1.00 17.08 ? 261 PRO A CA 1 ATOM 550 C C . PRO A 1 71 ? 68.215 -3.157 16.599 1.00 15.70 ? 261 PRO A C 1 ATOM 551 O O . PRO A 1 71 ? 68.927 -2.206 16.279 1.00 18.35 ? 261 PRO A O 1 ATOM 552 C CB . PRO A 1 71 ? 68.528 -4.967 14.834 1.00 16.73 ? 261 PRO A CB 1 ATOM 553 C CG . PRO A 1 71 ? 67.177 -5.616 14.737 1.00 15.80 ? 261 PRO A CG 1 ATOM 554 C CD . PRO A 1 71 ? 67.121 -6.445 15.990 1.00 11.31 ? 261 PRO A CD 1 ATOM 555 N N . GLU A 1 72 ? 67.041 -3.018 17.205 1.00 15.98 ? 262 GLU A N 1 ATOM 556 C CA . GLU A 1 72 ? 66.501 -1.714 17.570 1.00 21.47 ? 262 GLU A CA 1 ATOM 557 C C . GLU A 1 72 ? 67.115 -1.390 18.939 1.00 19.91 ? 262 GLU A C 1 ATOM 558 O O . GLU A 1 72 ? 66.623 -1.844 19.978 1.00 17.12 ? 262 GLU A O 1 ATOM 559 C CB . GLU A 1 72 ? 64.972 -1.808 17.646 1.00 28.03 ? 262 GLU A CB 1 ATOM 560 C CG . GLU A 1 72 ? 64.230 -0.483 17.640 1.00 40.35 ? 262 GLU A CG 1 ATOM 561 C CD . GLU A 1 72 ? 64.232 0.197 18.992 1.00 46.54 ? 262 GLU A CD 1 ATOM 562 O OE1 . GLU A 1 72 ? 65.320 0.593 19.459 1.00 47.65 ? 262 GLU A OE1 1 ATOM 563 O OE2 . GLU A 1 72 ? 63.141 0.330 19.589 1.00 48.20 ? 262 GLU A OE2 1 ATOM 564 N N . ALA A 1 73 ? 68.201 -0.616 18.920 1.00 14.35 ? 263 ALA A N 1 ATOM 565 C CA . ALA A 1 73 ? 68.944 -0.242 20.127 1.00 9.91 ? 263 ALA A CA 1 ATOM 566 C C . ALA A 1 73 ? 68.098 0.146 21.342 1.00 8.15 ? 263 ALA A C 1 ATOM 567 O O . ALA A 1 73 ? 68.249 -0.435 22.421 1.00 4.74 ? 263 ALA A O 1 ATOM 568 C CB . ALA A 1 73 ? 69.933 0.881 19.796 1.00 6.29 ? 263 ALA A CB 1 ATOM 569 N N . GLY A 1 74 ? 67.222 1.132 21.163 1.00 9.83 ? 264 GLY A N 1 ATOM 570 C CA . GLY A 1 74 ? 66.364 1.588 22.244 1.00 1.33 ? 264 GLY A CA 1 ATOM 571 C C . GLY A 1 74 ? 65.706 0.444 22.984 1.00 5.51 ? 264 GLY A C 1 ATOM 572 O O . GLY A 1 74 ? 65.824 0.333 24.204 1.00 8.23 ? 264 GLY A O 1 ATOM 573 N N . TYR A 1 75 ? 65.013 -0.415 22.248 1.00 5.47 ? 265 TYR A N 1 ATOM 574 C CA . TYR A 1 75 ? 64.346 -1.554 22.860 1.00 9.04 ? 265 TYR A CA 1 ATOM 575 C C . TYR A 1 75 ? 65.335 -2.403 23.656 1.00 12.56 ? 265 TYR A C 1 ATOM 576 O O . TYR A 1 75 ? 65.054 -2.812 24.782 1.00 15.95 ? 265 TYR A O 1 ATOM 577 C CB . TYR A 1 75 ? 63.692 -2.430 21.791 1.00 11.50 ? 265 TYR A CB 1 ATOM 578 C CG . TYR A 1 75 ? 63.122 -3.711 22.346 1.00 9.70 ? 265 TYR A CG 1 ATOM 579 C CD1 . TYR A 1 75 ? 61.788 -3.789 22.740 1.00 10.15 ? 265 TYR A CD1 1 ATOM 580 C CD2 . TYR A 1 75 ? 63.937 -4.826 22.545 1.00 11.35 ? 265 TYR A CD2 1 ATOM 581 C CE1 . TYR A 1 75 ? 61.276 -4.947 23.324 1.00 13.80 ? 265 TYR A CE1 1 ATOM 582 C CE2 . TYR A 1 75 ? 63.440 -5.986 23.130 1.00 17.44 ? 265 TYR A CE2 1 ATOM 583 C CZ . TYR A 1 75 ? 62.108 -6.040 23.518 1.00 17.87 ? 265 TYR A CZ 1 ATOM 584 O OH . TYR A 1 75 ? 61.617 -7.180 24.111 1.00 19.01 ? 265 TYR A OH 1 ATOM 585 N N . THR A 1 76 ? 66.487 -2.674 23.055 1.00 14.37 ? 266 THR A N 1 ATOM 586 C CA . THR A 1 76 ? 67.510 -3.492 23.694 1.00 15.84 ? 266 THR A CA 1 ATOM 587 C C . THR A 1 76 ? 68.137 -2.835 24.924 1.00 15.91 ? 266 THR A C 1 ATOM 588 O O . THR A 1 76 ? 68.297 -3.478 25.964 1.00 11.56 ? 266 THR A O 1 ATOM 589 C CB . THR A 1 76 ? 68.609 -3.858 22.689 1.00 12.74 ? 266 THR A CB 1 ATOM 590 O OG1 . THR A 1 76 ? 68.045 -4.675 21.652 1.00 10.45 ? 266 THR A OG1 1 ATOM 591 C CG2 . THR A 1 76 ? 69.730 -4.614 23.381 1.00 13.89 ? 266 THR A CG2 1 ATOM 592 N N . LEU A 1 77 ? 68.490 -1.559 24.815 1.00 14.55 ? 267 LEU A N 1 ATOM 593 C CA . LEU A 1 77 ? 69.077 -0.865 25.952 1.00 14.61 ? 267 LEU A CA 1 ATOM 594 C C . LEU A 1 77 ? 68.098 -0.916 27.115 1.00 15.56 ? 267 LEU A C 1 ATOM 595 O O . LEU A 1 77 ? 68.465 -1.253 28.238 1.00 13.30 ? 267 LEU A O 1 ATOM 596 C CB . LEU A 1 77 ? 69.367 0.591 25.607 1.00 12.85 ? 267 LEU A CB 1 ATOM 597 C CG . LEU A 1 77 ? 69.934 1.399 26.775 1.00 12.22 ? 267 LEU A CG 1 ATOM 598 C CD1 . LEU A 1 77 ? 71.259 0.797 27.205 1.00 14.21 ? 267 LEU A CD1 1 ATOM 599 C CD2 . LEU A 1 77 ? 70.113 2.846 26.364 1.00 16.63 ? 267 LEU A CD2 1 ATOM 600 N N . ASN A 1 78 ? 66.845 -0.583 26.828 1.00 16.67 ? 268 ASN A N 1 ATOM 601 C CA . ASN A 1 78 ? 65.796 -0.584 27.836 1.00 17.27 ? 268 ASN A CA 1 ATOM 602 C C . ASN A 1 78 ? 65.579 -1.965 28.443 1.00 17.14 ? 268 ASN A C 1 ATOM 603 O O . ASN A 1 78 ? 65.450 -2.101 29.659 1.00 16.19 ? 268 ASN A O 1 ATOM 604 C CB . ASN A 1 78 ? 64.482 -0.106 27.232 1.00 16.97 ? 268 ASN A CB 1 ATOM 605 C CG . ASN A 1 78 ? 63.396 0.005 28.261 1.00 16.65 ? 268 ASN A CG 1 ATOM 606 O OD1 . ASN A 1 78 ? 63.384 0.936 29.068 1.00 18.06 ? 268 ASN A OD1 1 ATOM 607 N ND2 . ASN A 1 78 ? 62.486 -0.960 28.264 1.00 18.40 ? 268 ASN A ND2 1 ATOM 608 N N . ALA A 1 79 ? 65.521 -2.984 27.589 1.00 15.84 ? 269 ALA A N 1 ATOM 609 C CA . ALA A 1 79 ? 65.327 -4.356 28.047 1.00 13.74 ? 269 ALA A CA 1 ATOM 610 C C . ALA A 1 79 ? 66.522 -4.792 28.887 1.00 15.02 ? 269 ALA A C 1 ATOM 611 O O . ALA A 1 79 ? 66.360 -5.421 29.929 1.00 22.79 ? 269 ALA A O 1 ATOM 612 C CB . ALA A 1 79 ? 65.151 -5.294 26.856 1.00 8.19 ? 269 ALA A CB 1 ATOM 613 N N . PHE A 1 80 ? 67.725 -4.458 28.436 1.00 13.60 ? 270 PHE A N 1 ATOM 614 C CA . PHE A 1 80 ? 68.924 -4.823 29.181 1.00 12.75 ? 270 PHE A CA 1 ATOM 615 C C . PHE A 1 80 ? 68.967 -4.107 30.529 1.00 14.60 ? 270 PHE A C 1 ATOM 616 O O . PHE A 1 80 ? 69.497 -4.636 31.508 1.00 10.94 ? 270 PHE A O 1 ATOM 617 C CB . PHE A 1 80 ? 70.180 -4.469 28.389 1.00 5.51 ? 270 PHE A CB 1 ATOM 618 C CG . PHE A 1 80 ? 71.449 -4.863 29.076 1.00 11.47 ? 270 PHE A CG 1 ATOM 619 C CD1 . PHE A 1 80 ? 71.712 -6.202 29.359 1.00 10.96 ? 270 PHE A CD1 1 ATOM 620 C CD2 . PHE A 1 80 ? 72.378 -3.898 29.454 1.00 13.76 ? 270 PHE A CD2 1 ATOM 621 C CE1 . PHE A 1 80 ? 72.881 -6.575 30.009 1.00 13.67 ? 270 PHE A CE1 1 ATOM 622 C CE2 . PHE A 1 80 ? 73.551 -4.258 30.104 1.00 14.83 ? 270 PHE A CE2 1 ATOM 623 C CZ . PHE A 1 80 ? 73.806 -5.600 30.383 1.00 19.81 ? 270 PHE A CZ 1 ATOM 624 N N . GLY A 1 81 ? 68.414 -2.897 30.569 1.00 17.21 ? 271 GLY A N 1 ATOM 625 C CA . GLY A 1 81 ? 68.394 -2.126 31.799 1.00 17.08 ? 271 GLY A CA 1 ATOM 626 C C . GLY A 1 81 ? 67.489 -2.757 32.841 1.00 19.87 ? 271 GLY A C 1 ATOM 627 O O . GLY A 1 81 ? 67.905 -2.989 33.980 1.00 17.54 ? 271 GLY A O 1 ATOM 628 N N . GLU A 1 82 ? 66.248 -3.033 32.448 1.00 16.60 ? 272 GLU A N 1 ATOM 629 C CA . GLU A 1 82 ? 65.274 -3.648 33.339 1.00 18.79 ? 272 GLU A CA 1 ATOM 630 C C . GLU A 1 82 ? 65.822 -4.969 33.854 1.00 16.73 ? 272 GLU A C 1 ATOM 631 O O . GLU A 1 82 ? 65.660 -5.307 35.024 1.00 19.65 ? 272 GLU A O 1 ATOM 632 C CB . GLU A 1 82 ? 63.960 -3.911 32.597 1.00 21.49 ? 272 GLU A CB 1 ATOM 633 C CG . GLU A 1 82 ? 63.222 -2.663 32.131 1.00 29.84 ? 272 GLU A CG 1 ATOM 634 C CD . GLU A 1 82 ? 62.600 -1.872 33.271 1.00 31.87 ? 272 GLU A CD 1 ATOM 635 O OE1 . GLU A 1 82 ? 61.932 -0.856 32.983 1.00 30.09 ? 272 GLU A OE1 1 ATOM 636 O OE2 . GLU A 1 82 ? 62.775 -2.263 34.447 1.00 35.65 ? 272 GLU A OE2 1 ATOM 637 N N . TRP A 1 83 ? 66.469 -5.714 32.966 1.00 16.09 ? 273 TRP A N 1 ATOM 638 C CA . TRP A 1 83 ? 67.039 -7.004 33.322 1.00 17.50 ? 273 TRP A CA 1 ATOM 639 C C . TRP A 1 83 ? 68.102 -6.865 34.410 1.00 20.26 ? 273 TRP A C 1 ATOM 640 O O . TRP A 1 83 ? 68.187 -7.694 35.315 1.00 21.31 ? 273 TRP A O 1 ATOM 641 C CB . TRP A 1 83 ? 67.649 -7.671 32.089 1.00 13.64 ? 273 TRP A CB 1 ATOM 642 C CG . TRP A 1 83 ? 68.223 -9.011 32.385 1.00 21.20 ? 273 TRP A CG 1 ATOM 643 C CD1 . TRP A 1 83 ? 67.534 -10.166 32.626 1.00 21.22 ? 273 TRP A CD1 1 ATOM 644 C CD2 . TRP A 1 83 ? 69.611 -9.328 32.553 1.00 21.81 ? 273 TRP A CD2 1 ATOM 645 N NE1 . TRP A 1 83 ? 68.407 -11.182 32.939 1.00 23.73 ? 273 TRP A NE1 1 ATOM 646 C CE2 . TRP A 1 83 ? 69.687 -10.694 32.903 1.00 22.12 ? 273 TRP A CE2 1 ATOM 647 C CE3 . TRP A 1 83 ? 70.796 -8.587 32.449 1.00 18.96 ? 273 TRP A CE3 1 ATOM 648 C CZ2 . TRP A 1 83 ? 70.904 -11.336 33.148 1.00 27.47 ? 273 TRP A CZ2 1 ATOM 649 C CZ3 . TRP A 1 83 ? 72.008 -9.226 32.693 1.00 19.47 ? 273 TRP A CZ3 1 ATOM 650 C CH2 . TRP A 1 83 ? 72.051 -10.587 33.040 1.00 28.99 ? 273 TRP A CH2 1 ATOM 651 N N . ARG A 1 84 ? 68.914 -5.818 34.322 1.00 23.55 ? 274 ARG A N 1 ATOM 652 C CA . ARG A 1 84 ? 69.962 -5.597 35.312 1.00 26.56 ? 274 ARG A CA 1 ATOM 653 C C . ARG A 1 84 ? 69.353 -5.295 36.683 1.00 30.20 ? 274 ARG A C 1 ATOM 654 O O . ARG A 1 84 ? 69.806 -5.817 37.701 1.00 32.97 ? 274 ARG A O 1 ATOM 655 C CB . ARG A 1 84 ? 70.861 -4.431 34.892 1.00 20.53 ? 274 ARG A CB 1 ATOM 656 C CG . ARG A 1 84 ? 72.133 -4.336 35.712 1.00 18.58 ? 274 ARG A CG 1 ATOM 657 C CD . ARG A 1 84 ? 72.468 -2.905 36.079 1.00 21.08 ? 274 ARG A CD 1 ATOM 658 N NE . ARG A 1 84 ? 73.614 -2.839 36.982 1.00 19.56 ? 274 ARG A NE 1 ATOM 659 C CZ . ARG A 1 84 ? 73.934 -1.775 37.712 1.00 22.40 ? 274 ARG A CZ 1 ATOM 660 N NH1 . ARG A 1 84 ? 73.193 -0.676 37.655 1.00 21.93 ? 274 ARG A NH1 1 ATOM 661 N NH2 . ARG A 1 84 ? 75.001 -1.809 38.500 1.00 17.97 ? 274 ARG A NH2 1 ATOM 662 N N . LYS A 1 85 ? 68.322 -4.455 36.695 1.00 29.03 ? 275 LYS A N 1 ATOM 663 C CA . LYS A 1 85 ? 67.649 -4.060 37.927 1.00 30.79 ? 275 LYS A CA 1 ATOM 664 C C . LYS A 1 85 ? 66.856 -5.164 38.624 1.00 29.82 ? 275 LYS A C 1 ATOM 665 O O . LYS A 1 85 ? 66.844 -5.241 39.851 1.00 29.11 ? 275 LYS A O 1 ATOM 666 C CB . LYS A 1 85 ? 66.699 -2.891 37.655 1.00 35.34 ? 275 LYS A CB 1 ATOM 667 C CG . LYS A 1 85 ? 65.843 -2.508 38.859 1.00 39.61 ? 275 LYS A CG 1 ATOM 668 C CD . LYS A 1 85 ? 64.560 -1.795 38.448 1.00 46.22 ? 275 LYS A CD 1 ATOM 669 C CE . LYS A 1 85 ? 64.832 -0.432 37.838 1.00 52.36 ? 275 LYS A CE 1 ATOM 670 N NZ . LYS A 1 85 ? 65.461 0.500 38.820 1.00 59.81 ? 275 LYS A NZ 1 ATOM 671 N N . THR A 1 86 ? 66.191 -6.011 37.847 1.00 28.60 ? 276 THR A N 1 ATOM 672 C CA . THR A 1 86 ? 65.369 -7.071 38.424 1.00 31.54 ? 276 THR A CA 1 ATOM 673 C C . THR A 1 86 ? 66.003 -8.456 38.485 1.00 29.94 ? 276 THR A C 1 ATOM 674 O O . THR A 1 86 ? 65.433 -9.361 39.091 1.00 32.10 ? 276 THR A O 1 ATOM 675 C CB . THR A 1 86 ? 64.030 -7.209 37.663 1.00 31.68 ? 276 THR A CB 1 ATOM 676 O OG1 . THR A 1 86 ? 64.276 -7.720 36.346 1.00 34.29 ? 276 THR A OG1 1 ATOM 677 C CG2 . THR A 1 86 ? 63.342 -5.859 37.545 1.00 33.14 ? 276 THR A CG2 1 ATOM 678 N N . ASP A 1 87 ? 67.171 -8.628 37.875 1.00 27.69 ? 277 ASP A N 1 ATOM 679 C CA . ASP A 1 87 ? 67.814 -9.935 37.866 1.00 27.02 ? 277 ASP A CA 1 ATOM 680 C C . ASP A 1 87 ? 69.291 -9.924 38.242 1.00 28.77 ? 277 ASP A C 1 ATOM 681 O O . ASP A 1 87 ? 69.667 -10.411 39.305 1.00 31.93 ? 277 ASP A O 1 ATOM 682 C CB . ASP A 1 87 ? 67.634 -10.581 36.486 1.00 29.87 ? 277 ASP A CB 1 ATOM 683 C CG . ASP A 1 87 ? 68.073 -12.040 36.451 1.00 31.49 ? 277 ASP A CG 1 ATOM 684 O OD1 . ASP A 1 87 ? 67.751 -12.727 35.459 1.00 28.44 ? 277 ASP A OD1 1 ATOM 685 O OD2 . ASP A 1 87 ? 68.738 -12.501 37.405 1.00 31.81 ? 277 ASP A OD2 1 ATOM 686 N N . LEU A 1 88 ? 70.130 -9.375 37.372 1.00 28.94 ? 278 LEU A N 1 ATOM 687 C CA . LEU A 1 88 ? 71.567 -9.338 37.630 1.00 31.02 ? 278 LEU A CA 1 ATOM 688 C C . LEU A 1 88 ? 71.966 -8.692 38.960 1.00 33.12 ? 278 LEU A C 1 ATOM 689 O O . LEU A 1 88 ? 72.578 -9.334 39.819 1.00 28.08 ? 278 LEU A O 1 ATOM 690 C CB . LEU A 1 88 ? 72.287 -8.615 36.490 1.00 27.48 ? 278 LEU A CB 1 ATOM 691 C CG . LEU A 1 88 ? 73.812 -8.597 36.606 1.00 18.08 ? 278 LEU A CG 1 ATOM 692 C CD1 . LEU A 1 88 ? 74.325 -10.020 36.596 1.00 15.99 ? 278 LEU A CD1 1 ATOM 693 C CD2 . LEU A 1 88 ? 74.414 -7.804 35.460 1.00 22.12 ? 278 LEU A CD2 1 ATOM 694 N N . LEU A 1 89 ? 71.620 -7.418 39.117 1.00 34.44 ? 279 LEU A N 1 ATOM 695 C CA . LEU A 1 89 ? 71.956 -6.661 40.319 1.00 32.88 ? 279 LEU A CA 1 ATOM 696 C C . LEU A 1 89 ? 71.418 -7.307 41.594 1.00 33.78 ? 279 LEU A C 1 ATOM 697 O O . LEU A 1 89 ? 71.823 -6.946 42.700 1.00 35.01 ? 279 LEU A O 1 ATOM 698 C CB . LEU A 1 89 ? 71.417 -5.234 40.191 1.00 31.32 ? 279 LEU A CB 1 ATOM 699 C CG . LEU A 1 89 ? 71.986 -4.155 41.113 1.00 31.99 ? 279 LEU A CG 1 ATOM 700 C CD1 . LEU A 1 89 ? 73.498 -4.051 40.929 1.00 26.88 ? 279 LEU A CD1 1 ATOM 701 C CD2 . LEU A 1 89 ? 71.320 -2.827 40.793 1.00 29.50 ? 279 LEU A CD2 1 ATOM 702 N N . THR A 1 90 ? 70.516 -8.269 41.433 1.00 31.63 ? 280 THR A N 1 ATOM 703 C CA . THR A 1 90 ? 69.919 -8.954 42.572 1.00 31.95 ? 280 THR A CA 1 ATOM 704 C C . THR A 1 90 ? 70.791 -10.106 43.071 1.00 31.35 ? 280 THR A C 1 ATOM 705 O O . THR A 1 90 ? 70.589 -10.609 44.174 1.00 34.22 ? 280 THR A O 1 ATOM 706 C CB . THR A 1 90 ? 68.508 -9.500 42.211 1.00 33.33 ? 280 THR A CB 1 ATOM 707 O OG1 . THR A 1 90 ? 67.632 -9.338 43.332 1.00 37.72 ? 280 THR A OG1 1 ATOM 708 C CG2 . THR A 1 90 ? 68.569 -10.982 41.853 1.00 29.59 ? 280 THR A CG2 1 ATOM 709 N N . ARG A 1 91 ? 71.760 -10.520 42.261 1.00 29.96 ? 281 ARG A N 1 ATOM 710 C CA . ARG A 1 91 ? 72.642 -11.620 42.636 1.00 29.56 ? 281 ARG A CA 1 ATOM 711 C C . ARG A 1 91 ? 74.122 -11.284 42.464 1.00 33.11 ? 281 ARG A C 1 ATOM 712 O O . ARG A 1 91 ? 74.989 -12.145 42.628 1.00 32.84 ? 281 ARG A O 1 ATOM 713 C CB . ARG A 1 91 ? 72.291 -12.864 41.817 1.00 28.83 ? 281 ARG A CB 1 ATOM 714 C CG . ARG A 1 91 ? 72.248 -12.625 40.319 1.00 28.56 ? 281 ARG A CG 1 ATOM 715 C CD . ARG A 1 91 ? 71.591 -13.786 39.586 1.00 28.84 ? 281 ARG A CD 1 ATOM 716 N NE . ARG A 1 91 ? 71.412 -13.491 38.166 1.00 30.43 ? 281 ARG A NE 1 ATOM 717 C CZ . ARG A 1 91 ? 72.413 -13.297 37.313 1.00 29.50 ? 281 ARG A CZ 1 ATOM 718 N NH1 . ARG A 1 91 ? 73.668 -13.369 37.734 1.00 34.27 ? 281 ARG A NH1 1 ATOM 719 N NH2 . ARG A 1 91 ? 72.160 -13.024 36.040 1.00 28.68 ? 281 ARG A NH2 1 ATOM 720 N N . LYS A 1 92 ? 74.409 -10.031 42.127 1.00 32.25 ? 282 LYS A N 1 ATOM 721 C CA . LYS A 1 92 ? 75.789 -9.596 41.955 1.00 33.07 ? 282 LYS A CA 1 ATOM 722 C C . LYS A 1 92 ? 75.848 -8.086 42.079 1.00 31.54 ? 282 LYS A C 1 ATOM 723 O O . LYS A 1 92 ? 75.254 -7.368 41.279 1.00 34.82 ? 282 LYS A O 1 ATOM 724 C CB . LYS A 1 92 ? 76.328 -10.015 40.585 1.00 35.81 ? 282 LYS A CB 1 ATOM 725 C CG . LYS A 1 92 ? 77.801 -10.429 40.595 1.00 39.82 ? 282 LYS A CG 1 ATOM 726 C CD . LYS A 1 92 ? 78.696 -9.417 41.301 1.00 32.01 ? 282 LYS A CD 1 ATOM 727 C CE . LYS A 1 92 ? 80.136 -9.916 41.352 1.00 39.34 ? 282 LYS A CE 1 ATOM 728 N NZ . LYS A 1 92 ? 81.039 -9.013 42.124 1.00 41.20 ? 282 LYS A NZ 1 ATOM 729 N N . LYS A 1 93 ? 76.566 -7.608 43.087 1.00 30.87 ? 283 LYS A N 1 ATOM 730 C CA . LYS A 1 93 ? 76.691 -6.179 43.316 1.00 30.54 ? 283 LYS A CA 1 ATOM 731 C C . LYS A 1 93 ? 77.767 -5.567 42.428 1.00 29.00 ? 283 LYS A C 1 ATOM 732 O O . LYS A 1 93 ? 78.935 -5.944 42.493 1.00 27.14 ? 283 LYS A O 1 ATOM 733 C CB . LYS A 1 93 ? 76.996 -5.907 44.793 1.00 34.95 ? 283 LYS A CB 1 ATOM 734 C CG . LYS A 1 93 ? 75.817 -6.171 45.734 1.00 43.78 ? 283 LYS A CG 1 ATOM 735 C CD . LYS A 1 93 ? 75.399 -7.642 45.741 1.00 49.83 ? 283 LYS A CD 1 ATOM 736 C CE . LYS A 1 93 ? 74.126 -7.874 46.554 1.00 50.45 ? 283 LYS A CE 1 ATOM 737 N NZ . LYS A 1 93 ? 74.281 -7.505 47.990 1.00 50.87 ? 283 LYS A NZ 1 ATOM 738 N N . HIS A 1 94 ? 77.353 -4.629 41.584 1.00 26.56 ? 284 HIS A N 1 ATOM 739 C CA . HIS A 1 94 ? 78.262 -3.945 40.678 1.00 24.26 ? 284 HIS A CA 1 ATOM 740 C C . HIS A 1 94 ? 77.743 -2.537 40.418 1.00 22.46 ? 284 HIS A C 1 ATOM 741 O O . HIS A 1 94 ? 76.596 -2.224 40.725 1.00 25.16 ? 284 HIS A O 1 ATOM 742 C CB . HIS A 1 94 ? 78.381 -4.711 39.361 1.00 24.80 ? 284 HIS A CB 1 ATOM 743 C CG . HIS A 1 94 ? 77.085 -4.859 38.628 1.00 21.50 ? 284 HIS A CG 1 ATOM 744 N ND1 . HIS A 1 94 ? 76.039 -5.616 39.111 1.00 18.61 ? 284 HIS A ND1 1 ATOM 745 C CD2 . HIS A 1 94 ? 76.666 -4.348 37.447 1.00 19.82 ? 284 HIS A CD2 1 ATOM 746 C CE1 . HIS A 1 94 ? 75.032 -5.566 38.257 1.00 20.88 ? 284 HIS A CE1 1 ATOM 747 N NE2 . HIS A 1 94 ? 75.387 -4.804 37.239 1.00 20.58 ? 284 HIS A NE2 1 ATOM 748 N N . ASP A 1 95 ? 78.584 -1.695 39.837 1.00 24.79 ? 285 ASP A N 1 ATOM 749 C CA . ASP A 1 95 ? 78.212 -0.309 39.578 1.00 26.24 ? 285 ASP A CA 1 ATOM 750 C C . ASP A 1 95 ? 77.683 -0.040 38.173 1.00 27.24 ? 285 ASP A C 1 ATOM 751 O O . ASP A 1 95 ? 76.811 0.808 37.987 1.00 32.65 ? 285 ASP A O 1 ATOM 752 C CB . ASP A 1 95 ? 79.423 0.588 39.834 1.00 23.72 ? 285 ASP A CB 1 ATOM 753 C CG . ASP A 1 95 ? 80.084 0.299 41.163 1.00 26.09 ? 285 ASP A CG 1 ATOM 754 O OD1 . ASP A 1 95 ? 81.309 0.510 41.276 1.00 21.89 ? 285 ASP A OD1 1 ATOM 755 O OD2 . ASP A 1 95 ? 79.377 -0.134 42.098 1.00 31.87 ? 285 ASP A OD2 1 ATOM 756 N N . ASN A 1 96 ? 78.200 -0.768 37.189 1.00 26.41 ? 286 ASN A N 1 ATOM 757 C CA . ASN A 1 96 ? 77.800 -0.553 35.805 1.00 21.53 ? 286 ASN A CA 1 ATOM 758 C C . ASN A 1 96 ? 77.827 -1.860 35.012 1.00 21.98 ? 286 ASN A C 1 ATOM 759 O O . ASN A 1 96 ? 78.639 -2.744 35.293 1.00 23.60 ? 286 ASN A O 1 ATOM 760 C CB . ASN A 1 96 ? 78.753 0.480 35.195 1.00 16.30 ? 286 ASN A CB 1 ATOM 761 C CG . ASN A 1 96 ? 78.287 0.998 33.859 1.00 18.80 ? 286 ASN A CG 1 ATOM 762 O OD1 . ASN A 1 96 ? 78.601 0.428 32.813 1.00 16.30 ? 286 ASN A OD1 1 ATOM 763 N ND2 . ASN A 1 96 ? 77.528 2.090 33.884 1.00 11.02 ? 286 ASN A ND2 1 ATOM 764 N N . ALA A 1 97 ? 76.933 -1.983 34.031 1.00 19.31 ? 287 ALA A N 1 ATOM 765 C CA . ALA A 1 97 ? 76.864 -3.188 33.200 1.00 16.98 ? 287 ALA A CA 1 ATOM 766 C C . ALA A 1 97 ? 76.730 -2.861 31.716 1.00 16.53 ? 287 ALA A C 1 ATOM 767 O O . ALA A 1 97 ? 75.943 -1.999 31.325 1.00 19.29 ? 287 ALA A O 1 ATOM 768 C CB . ALA A 1 97 ? 75.702 -4.067 33.640 1.00 6.05 ? 287 ALA A CB 1 ATOM 769 N N . GLN A 1 98 ? 77.510 -3.560 30.897 1.00 15.24 ? 288 GLN A N 1 ATOM 770 C CA . GLN A 1 98 ? 77.501 -3.364 29.456 1.00 12.71 ? 288 GLN A CA 1 ATOM 771 C C . GLN A 1 98 ? 77.201 -4.690 28.759 1.00 16.99 ? 288 GLN A C 1 ATOM 772 O O . GLN A 1 98 ? 77.668 -5.753 29.185 1.00 11.28 ? 288 GLN A O 1 ATOM 773 C CB . GLN A 1 98 ? 78.861 -2.838 28.989 1.00 14.20 ? 288 GLN A CB 1 ATOM 774 C CG . GLN A 1 98 ? 79.311 -1.562 29.676 1.00 24.25 ? 288 GLN A CG 1 ATOM 775 C CD . GLN A 1 98 ? 78.523 -0.346 29.232 1.00 31.71 ? 288 GLN A CD 1 ATOM 776 O OE1 . GLN A 1 98 ? 78.592 0.715 29.853 1.00 36.20 ? 288 GLN A OE1 1 ATOM 777 N NE2 . GLN A 1 98 ? 77.776 -0.492 28.146 1.00 38.15 ? 288 GLN A NE2 1 ATOM 778 N N . LEU A 1 99 ? 76.416 -4.621 27.689 1.00 19.88 ? 289 LEU A N 1 ATOM 779 C CA . LEU A 1 99 ? 76.053 -5.804 26.916 1.00 16.34 ? 289 LEU A CA 1 ATOM 780 C C . LEU A 1 99 ? 76.779 -5.792 25.581 1.00 15.23 ? 289 LEU A C 1 ATOM 781 O O . LEU A 1 99 ? 76.612 -4.868 24.787 1.00 14.32 ? 289 LEU A O 1 ATOM 782 C CB . LEU A 1 99 ? 74.550 -5.834 26.656 1.00 9.25 ? 289 LEU A CB 1 ATOM 783 C CG . LEU A 1 99 ? 74.130 -6.956 25.705 1.00 12.66 ? 289 LEU A CG 1 ATOM 784 C CD1 . LEU A 1 99 ? 74.254 -8.285 26.423 1.00 15.01 ? 289 LEU A CD1 1 ATOM 785 C CD2 . LEU A 1 99 ? 72.702 -6.737 25.227 1.00 14.01 ? 289 LEU A CD2 1 ATOM 786 N N . LEU A 1 100 ? 77.588 -6.815 25.334 1.00 14.76 ? 290 LEU A N 1 ATOM 787 C CA . LEU A 1 100 ? 78.320 -6.900 24.076 1.00 15.03 ? 290 LEU A CA 1 ATOM 788 C C . LEU A 1 100 ? 77.529 -7.802 23.144 1.00 13.87 ? 290 LEU A C 1 ATOM 789 O O . LEU A 1 100 ? 77.394 -9.000 23.401 1.00 16.71 ? 290 LEU A O 1 ATOM 790 C CB . LEU A 1 100 ? 79.716 -7.478 24.303 1.00 14.32 ? 290 LEU A CB 1 ATOM 791 C CG . LEU A 1 100 ? 80.684 -7.332 23.129 1.00 15.91 ? 290 LEU A CG 1 ATOM 792 C CD1 . LEU A 1 100 ? 80.935 -5.856 22.861 1.00 13.33 ? 290 LEU A CD1 1 ATOM 793 C CD2 . LEU A 1 100 ? 81.993 -8.039 23.452 1.00 16.90 ? 290 LEU A CD2 1 ATOM 794 N N . THR A 1 101 ? 77.001 -7.225 22.070 1.00 7.14 ? 291 THR A N 1 ATOM 795 C CA . THR A 1 101 ? 76.203 -7.988 21.120 1.00 11.76 ? 291 THR A CA 1 ATOM 796 C C . THR A 1 101 ? 76.852 -8.080 19.744 1.00 11.20 ? 291 THR A C 1 ATOM 797 O O . THR A 1 101 ? 77.478 -7.130 19.277 1.00 10.91 ? 291 THR A O 1 ATOM 798 C CB . THR A 1 101 ? 74.781 -7.372 20.965 1.00 12.74 ? 291 THR A CB 1 ATOM 799 O OG1 . THR A 1 101 ? 74.021 -8.133 20.015 1.00 7.29 ? 291 THR A OG1 1 ATOM 800 C CG2 . THR A 1 101 ? 74.874 -5.926 20.493 1.00 6.60 ? 291 THR A CG2 1 ATOM 801 N N . ALA A 1 102 ? 76.687 -9.232 19.100 1.00 11.71 ? 292 ALA A N 1 ATOM 802 C CA . ALA A 1 102 ? 77.244 -9.461 17.773 1.00 15.52 ? 292 ALA A CA 1 ATOM 803 C C . ALA A 1 102 ? 76.210 -9.110 16.714 1.00 18.71 ? 292 ALA A C 1 ATOM 804 O O . ALA A 1 102 ? 76.480 -9.183 15.515 1.00 25.35 ? 292 ALA A O 1 ATOM 805 C CB . ALA A 1 102 ? 77.671 -10.919 17.624 1.00 7.84 ? 292 ALA A CB 1 ATOM 806 N N . ILE A 1 103 ? 75.021 -8.730 17.165 1.00 13.81 ? 293 ILE A N 1 ATOM 807 C CA . ILE A 1 103 ? 73.948 -8.369 16.252 1.00 16.53 ? 293 ILE A CA 1 ATOM 808 C C . ILE A 1 103 ? 74.225 -7.017 15.600 1.00 21.39 ? 293 ILE A C 1 ATOM 809 O O . ILE A 1 103 ? 74.843 -6.136 16.199 1.00 22.99 ? 293 ILE A O 1 ATOM 810 C CB . ILE A 1 103 ? 72.595 -8.338 16.995 1.00 19.76 ? 293 ILE A CB 1 ATOM 811 C CG1 . ILE A 1 103 ? 72.227 -9.763 17.421 1.00 21.16 ? 293 ILE A CG1 1 ATOM 812 C CG2 . ILE A 1 103 ? 71.518 -7.725 16.115 1.00 16.79 ? 293 ILE A CG2 1 ATOM 813 C CD1 . ILE A 1 103 ? 70.898 -9.888 18.113 1.00 34.81 ? 293 ILE A CD1 1 ATOM 814 N N . ASP A 1 104 ? 73.772 -6.859 14.363 1.00 19.57 ? 294 ASP A N 1 ATOM 815 C CA . ASP A 1 104 ? 73.990 -5.619 13.641 1.00 20.35 ? 294 ASP A CA 1 ATOM 816 C C . ASP A 1 104 ? 72.894 -4.613 13.973 1.00 20.73 ? 294 ASP A C 1 ATOM 817 O O . ASP A 1 104 ? 71.820 -4.618 13.373 1.00 23.49 ? 294 ASP A O 1 ATOM 818 C CB . ASP A 1 104 ? 74.040 -5.899 12.139 1.00 20.15 ? 294 ASP A CB 1 ATOM 819 C CG . ASP A 1 104 ? 74.627 -4.749 11.356 1.00 24.00 ? 294 ASP A CG 1 ATOM 820 O OD1 . ASP A 1 104 ? 75.424 -3.979 11.938 1.00 22.72 ? 294 ASP A OD1 1 ATOM 821 O OD2 . ASP A 1 104 ? 74.303 -4.624 10.157 1.00 24.78 ? 294 ASP A OD2 1 ATOM 822 N N . LEU A 1 105 ? 73.185 -3.753 14.942 1.00 22.12 ? 295 LEU A N 1 ATOM 823 C CA . LEU A 1 105 ? 72.247 -2.738 15.406 1.00 21.89 ? 295 LEU A CA 1 ATOM 824 C C . LEU A 1 105 ? 71.812 -1.777 14.305 1.00 23.37 ? 295 LEU A C 1 ATOM 825 O O . LEU A 1 105 ? 72.546 -1.547 13.344 1.00 23.77 ? 295 LEU A O 1 ATOM 826 C CB . LEU A 1 105 ? 72.878 -1.947 16.552 1.00 20.00 ? 295 LEU A CB 1 ATOM 827 C CG . LEU A 1 105 ? 73.393 -2.765 17.737 1.00 20.45 ? 295 LEU A CG 1 ATOM 828 C CD1 . LEU A 1 105 ? 74.160 -1.853 18.683 1.00 22.07 ? 295 LEU A CD1 1 ATOM 829 C CD2 . LEU A 1 105 ? 72.229 -3.438 18.451 1.00 15.49 ? 295 LEU A CD2 1 ATOM 830 N N . ASP A 1 106 ? 70.620 -1.208 14.454 1.00 22.38 ? 296 ASP A N 1 ATOM 831 C CA . ASP A 1 106 ? 70.113 -0.272 13.460 1.00 26.49 ? 296 ASP A CA 1 ATOM 832 C C . ASP A 1 106 ? 70.705 1.121 13.630 1.00 29.47 ? 296 ASP A C 1 ATOM 833 O O . ASP A 1 106 ? 70.586 1.734 14.691 1.00 32.89 ? 296 ASP A O 1 ATOM 834 C CB . ASP A 1 106 ? 68.584 -0.170 13.527 1.00 24.91 ? 296 ASP A CB 1 ATOM 835 C CG . ASP A 1 106 ? 67.889 -1.482 13.208 1.00 30.41 ? 296 ASP A CG 1 ATOM 836 O OD1 . ASP A 1 106 ? 68.238 -2.119 12.193 1.00 30.25 ? 296 ASP A OD1 1 ATOM 837 O OD2 . ASP A 1 106 ? 66.978 -1.871 13.970 1.00 37.16 ? 296 ASP A OD2 1 ATOM 838 N N . ARG A 1 107 ? 71.359 1.604 12.578 1.00 31.71 ? 297 ARG A N 1 ATOM 839 C CA . ARG A 1 107 ? 71.942 2.942 12.563 1.00 29.12 ? 297 ARG A CA 1 ATOM 840 C C . ARG A 1 107 ? 73.095 3.226 13.523 1.00 29.49 ? 297 ARG A C 1 ATOM 841 O O . ARG A 1 107 ? 74.031 3.942 13.169 1.00 34.40 ? 297 ARG A O 1 ATOM 842 C CB . ARG A 1 107 ? 70.834 3.967 12.790 1.00 25.23 ? 297 ARG A CB 1 ATOM 843 C CG . ARG A 1 107 ? 69.716 3.873 11.768 1.00 25.05 ? 297 ARG A CG 1 ATOM 844 C CD . ARG A 1 107 ? 68.623 4.870 12.073 1.00 25.84 ? 297 ARG A CD 1 ATOM 845 N NE . ARG A 1 107 ? 67.954 4.562 13.330 1.00 20.71 ? 297 ARG A NE 1 ATOM 846 C CZ . ARG A 1 107 ? 67.603 5.478 14.224 1.00 28.41 ? 297 ARG A CZ 1 ATOM 847 N NH1 . ARG A 1 107 ? 67.864 6.760 13.997 1.00 31.12 ? 297 ARG A NH1 1 ATOM 848 N NH2 . ARG A 1 107 ? 66.990 5.112 15.343 1.00 30.15 ? 297 ARG A NH2 1 ATOM 849 N N . VAL A 1 108 ? 73.033 2.683 14.733 1.00 26.59 ? 298 VAL A N 1 ATOM 850 C CA . VAL A 1 108 ? 74.090 2.916 15.712 1.00 19.84 ? 298 VAL A CA 1 ATOM 851 C C . VAL A 1 108 ? 74.917 1.663 15.978 1.00 18.87 ? 298 VAL A C 1 ATOM 852 O O . VAL A 1 108 ? 74.528 0.559 15.592 1.00 14.75 ? 298 VAL A O 1 ATOM 853 C CB . VAL A 1 108 ? 73.504 3.401 17.053 1.00 18.66 ? 298 VAL A CB 1 ATOM 854 C CG1 . VAL A 1 108 ? 72.731 4.677 16.844 1.00 13.96 ? 298 VAL A CG1 1 ATOM 855 C CG2 . VAL A 1 108 ? 72.604 2.328 17.652 1.00 17.82 ? 298 VAL A CG2 1 ATOM 856 N N . ILE A 1 109 ? 76.064 1.844 16.628 1.00 14.60 ? 299 ILE A N 1 ATOM 857 C CA . ILE A 1 109 ? 76.930 0.721 16.971 1.00 14.32 ? 299 ILE A CA 1 ATOM 858 C C . ILE A 1 109 ? 77.013 0.609 18.488 1.00 13.44 ? 299 ILE A C 1 ATOM 859 O O . ILE A 1 109 ? 77.805 -0.168 19.024 1.00 8.00 ? 299 ILE A O 1 ATOM 860 C CB . ILE A 1 109 ? 78.359 0.894 16.424 1.00 14.63 ? 299 ILE A CB 1 ATOM 861 C CG1 . ILE A 1 109 ? 78.949 2.215 16.922 1.00 13.52 ? 299 ILE A CG1 1 ATOM 862 C CG2 . ILE A 1 109 ? 78.349 0.805 14.910 1.00 9.05 ? 299 ILE A CG2 1 ATOM 863 C CD1 . ILE A 1 109 ? 80.423 2.371 16.614 1.00 18.96 ? 299 ILE A CD1 1 ATOM 864 N N . GLY A 1 110 ? 76.186 1.399 19.166 1.00 10.58 ? 300 GLY A N 1 ATOM 865 C CA . GLY A 1 110 ? 76.154 1.392 20.616 1.00 8.67 ? 300 GLY A CA 1 ATOM 866 C C . GLY A 1 110 ? 75.065 2.314 21.131 1.00 10.19 ? 300 GLY A C 1 ATOM 867 O O . GLY A 1 110 ? 74.514 3.108 20.371 1.00 11.00 ? 300 GLY A O 1 ATOM 868 N N . LEU A 1 111 ? 74.750 2.211 22.418 1.00 7.25 ? 301 LEU A N 1 ATOM 869 C CA . LEU A 1 111 ? 73.725 3.053 23.019 1.00 6.75 ? 301 LEU A CA 1 ATOM 870 C C . LEU A 1 111 ? 73.794 2.978 24.541 1.00 11.33 ? 301 LEU A C 1 ATOM 871 O O . LEU A 1 111 ? 74.016 1.905 25.105 1.00 13.85 ? 301 LEU A O 1 ATOM 872 C CB . LEU A 1 111 ? 72.334 2.615 22.556 1.00 5.14 ? 301 LEU A CB 1 ATOM 873 C CG . LEU A 1 111 ? 71.213 3.581 22.952 1.00 9.54 ? 301 LEU A CG 1 ATOM 874 C CD1 . LEU A 1 111 ? 71.389 4.890 22.180 1.00 1.00 ? 301 LEU A CD1 1 ATOM 875 C CD2 . LEU A 1 111 ? 69.855 2.961 22.658 1.00 6.47 ? 301 LEU A CD2 1 ATOM 876 N N . ALA A 1 112 ? 73.595 4.116 25.203 1.00 11.45 ? 302 ALA A N 1 ATOM 877 C CA . ALA A 1 112 ? 73.643 4.159 26.658 1.00 10.93 ? 302 ALA A CA 1 ATOM 878 C C . ALA A 1 112 ? 73.012 5.419 27.226 1.00 12.83 ? 302 ALA A C 1 ATOM 879 O O . ALA A 1 112 ? 73.129 6.494 26.644 1.00 18.41 ? 302 ALA A O 1 ATOM 880 C CB . ALA A 1 112 ? 75.086 4.062 27.124 1.00 8.47 ? 302 ALA A CB 1 ATOM 881 N N . TYR A 1 113 ? 72.347 5.275 28.370 1.00 12.21 ? 303 TYR A N 1 ATOM 882 C CA . TYR A 1 113 ? 71.715 6.399 29.058 1.00 12.99 ? 303 TYR A CA 1 ATOM 883 C C . TYR A 1 113 ? 72.808 7.404 29.461 1.00 16.76 ? 303 TYR A C 1 ATOM 884 O O . TYR A 1 113 ? 73.968 7.024 29.629 1.00 18.86 ? 303 TYR A O 1 ATOM 885 C CB . TYR A 1 113 ? 71.003 5.895 30.313 1.00 9.83 ? 303 TYR A CB 1 ATOM 886 C CG . TYR A 1 113 ? 69.934 4.857 30.053 1.00 8.76 ? 303 TYR A CG 1 ATOM 887 C CD1 . TYR A 1 113 ? 68.722 5.208 29.461 1.00 6.36 ? 303 TYR A CD1 1 ATOM 888 C CD2 . TYR A 1 113 ? 70.134 3.521 30.402 1.00 14.80 ? 303 TYR A CD2 1 ATOM 889 C CE1 . TYR A 1 113 ? 67.734 4.259 29.224 1.00 8.01 ? 303 TYR A CE1 1 ATOM 890 C CE2 . TYR A 1 113 ? 69.152 2.560 30.170 1.00 13.74 ? 303 TYR A CE2 1 ATOM 891 C CZ . TYR A 1 113 ? 67.954 2.936 29.579 1.00 11.88 ? 303 TYR A CZ 1 ATOM 892 O OH . TYR A 1 113 ? 66.982 1.992 29.332 1.00 12.88 ? 303 TYR A OH 1 ATOM 893 N N . VAL A 1 114 ? 72.449 8.676 29.623 1.00 16.13 ? 304 VAL A N 1 ATOM 894 C CA . VAL A 1 114 ? 73.438 9.689 29.999 1.00 14.83 ? 304 VAL A CA 1 ATOM 895 C C . VAL A 1 114 ? 73.358 10.104 31.467 1.00 17.72 ? 304 VAL A C 1 ATOM 896 O O . VAL A 1 114 ? 72.268 10.230 32.031 1.00 14.73 ? 304 VAL A O 1 ATOM 897 C CB . VAL A 1 114 ? 73.310 10.973 29.136 1.00 11.35 ? 304 VAL A CB 1 ATOM 898 C CG1 . VAL A 1 114 ? 73.537 10.650 27.668 1.00 10.42 ? 304 VAL A CG1 1 ATOM 899 C CG2 . VAL A 1 114 ? 71.947 11.596 29.339 1.00 22.45 ? 304 VAL A CG2 1 ATOM 900 N N . GLY A 1 115 ? 74.526 10.323 32.069 1.00 19.76 ? 305 GLY A N 1 ATOM 901 C CA . GLY A 1 115 ? 74.597 10.731 33.461 1.00 15.37 ? 305 GLY A CA 1 ATOM 902 C C . GLY A 1 115 ? 73.733 9.857 34.338 1.00 15.52 ? 305 GLY A C 1 ATOM 903 O O . GLY A 1 115 ? 72.870 10.352 35.058 1.00 11.09 ? 305 GLY A O 1 ATOM 904 N N . SER A 1 116 ? 73.977 8.552 34.290 1.00 18.13 ? 306 SER A N 1 ATOM 905 C CA . SER A 1 116 ? 73.190 7.607 35.063 1.00 17.59 ? 306 SER A CA 1 ATOM 906 C C . SER A 1 116 ? 74.015 6.573 35.824 1.00 20.24 ? 306 SER A C 1 ATOM 907 O O . SER A 1 116 ? 73.488 5.543 36.249 1.00 24.20 ? 306 SER A O 1 ATOM 908 C CB . SER A 1 116 ? 72.214 6.904 34.127 1.00 20.34 ? 306 SER A CB 1 ATOM 909 O OG . SER A 1 116 ? 72.875 6.515 32.938 1.00 24.81 ? 306 SER A OG 1 ATOM 910 N N . MET A 1 117 ? 75.305 6.841 35.999 1.00 19.63 ? 307 MET A N 1 ATOM 911 C CA . MET A 1 117 ? 76.171 5.916 36.721 1.00 19.26 ? 307 MET A CA 1 ATOM 912 C C . MET A 1 117 ? 75.570 5.599 38.089 1.00 23.58 ? 307 MET A C 1 ATOM 913 O O . MET A 1 117 ? 75.168 6.504 38.822 1.00 25.16 ? 307 MET A O 1 ATOM 914 C CB . MET A 1 117 ? 77.566 6.522 36.898 1.00 17.93 ? 307 MET A CB 1 ATOM 915 C CG . MET A 1 117 ? 78.569 5.615 37.601 1.00 18.34 ? 307 MET A CG 1 ATOM 916 S SD . MET A 1 117 ? 78.885 4.058 36.723 1.00 21.64 ? 307 MET A SD 1 ATOM 917 C CE . MET A 1 117 ? 79.664 4.676 35.222 1.00 13.25 ? 307 MET A CE 1 ATOM 918 N N . CYS A 1 118 ? 75.506 4.308 38.410 1.00 23.52 ? 308 CYS A N 1 ATOM 919 C CA . CYS A 1 118 ? 74.973 3.813 39.680 1.00 23.47 ? 308 CYS A CA 1 ATOM 920 C C . CYS A 1 118 ? 73.472 3.553 39.697 1.00 21.18 ? 308 CYS A C 1 ATOM 921 O O . CYS A 1 118 ? 72.989 2.815 40.549 1.00 22.79 ? 308 CYS A O 1 ATOM 922 C CB . CYS A 1 118 ? 75.326 4.756 40.837 1.00 25.27 ? 308 CYS A CB 1 ATOM 923 S SG . CYS A 1 118 ? 77.110 5.003 41.116 1.00 36.61 ? 308 CYS A SG 1 ATOM 924 N N . HIS A 1 119 ? 72.723 4.155 38.780 1.00 22.53 ? 309 HIS A N 1 ATOM 925 C CA . HIS A 1 119 ? 71.285 3.918 38.760 1.00 23.46 ? 309 HIS A CA 1 ATOM 926 C C . HIS A 1 119 ? 71.046 2.446 38.451 1.00 25.79 ? 309 HIS A C 1 ATOM 927 O O . HIS A 1 119 ? 71.602 1.909 37.493 1.00 29.16 ? 309 HIS A O 1 ATOM 928 C CB . HIS A 1 119 ? 70.595 4.783 37.708 1.00 22.60 ? 309 HIS A CB 1 ATOM 929 C CG . HIS A 1 119 ? 69.114 4.575 37.642 1.00 26.54 ? 309 HIS A CG 1 ATOM 930 N ND1 . HIS A 1 119 ? 68.548 3.399 37.197 1.00 29.47 ? 309 HIS A ND1 1 ATOM 931 C CD2 . HIS A 1 119 ? 68.083 5.379 37.991 1.00 26.23 ? 309 HIS A CD2 1 ATOM 932 C CE1 . HIS A 1 119 ? 67.232 3.488 37.273 1.00 28.17 ? 309 HIS A CE1 1 ATOM 933 N NE2 . HIS A 1 119 ? 66.924 4.680 37.752 1.00 30.60 ? 309 HIS A NE2 1 ATOM 934 N N . PRO A 1 120 ? 70.212 1.772 39.259 1.00 26.79 ? 310 PRO A N 1 ATOM 935 C CA . PRO A 1 120 ? 69.921 0.351 39.050 1.00 29.06 ? 310 PRO A CA 1 ATOM 936 C C . PRO A 1 120 ? 69.611 -0.062 37.610 1.00 30.74 ? 310 PRO A C 1 ATOM 937 O O . PRO A 1 120 ? 70.048 -1.123 37.160 1.00 31.73 ? 310 PRO A O 1 ATOM 938 C CB . PRO A 1 120 ? 68.754 0.089 40.008 1.00 27.57 ? 310 PRO A CB 1 ATOM 939 C CG . PRO A 1 120 ? 68.142 1.444 40.205 1.00 26.26 ? 310 PRO A CG 1 ATOM 940 C CD . PRO A 1 120 ? 69.345 2.329 40.309 1.00 22.15 ? 310 PRO A CD 1 ATOM 941 N N . LYS A 1 121 ? 68.876 0.776 36.885 1.00 29.54 ? 311 LYS A N 1 ATOM 942 C CA . LYS A 1 121 ? 68.521 0.465 35.504 1.00 28.16 ? 311 LYS A CA 1 ATOM 943 C C . LYS A 1 121 ? 69.328 1.233 34.460 1.00 27.51 ? 311 LYS A C 1 ATOM 944 O O . LYS A 1 121 ? 69.834 0.651 33.498 1.00 28.36 ? 311 LYS A O 1 ATOM 945 C CB . LYS A 1 121 ? 67.034 0.736 35.274 1.00 29.41 ? 311 LYS A CB 1 ATOM 946 C CG . LYS A 1 121 ? 66.569 0.481 33.845 1.00 30.09 ? 311 LYS A CG 1 ATOM 947 C CD . LYS A 1 121 ? 65.153 0.989 33.632 1.00 29.59 ? 311 LYS A CD 1 ATOM 948 C CE . LYS A 1 121 ? 64.726 0.842 32.182 1.00 31.63 ? 311 LYS A CE 1 ATOM 949 N NZ . LYS A 1 121 ? 63.390 1.449 31.934 1.00 28.58 ? 311 LYS A NZ 1 ATOM 950 N N . ARG A 1 122 ? 69.447 2.542 34.652 1.00 26.80 ? 312 ARG A N 1 ATOM 951 C CA . ARG A 1 122 ? 70.155 3.387 33.703 1.00 22.85 ? 312 ARG A CA 1 ATOM 952 C C . ARG A 1 122 ? 71.679 3.386 33.747 1.00 21.75 ? 312 ARG A C 1 ATOM 953 O O . ARG A 1 122 ? 72.321 4.104 32.985 1.00 20.92 ? 312 ARG A O 1 ATOM 954 C CB . ARG A 1 122 ? 69.631 4.816 33.814 1.00 25.89 ? 312 ARG A CB 1 ATOM 955 C CG . ARG A 1 122 ? 68.233 4.978 33.247 1.00 30.46 ? 312 ARG A CG 1 ATOM 956 C CD . ARG A 1 122 ? 67.813 6.431 33.226 1.00 42.84 ? 312 ARG A CD 1 ATOM 957 N NE . ARG A 1 122 ? 67.255 6.871 34.500 1.00 52.59 ? 312 ARG A NE 1 ATOM 958 C CZ . ARG A 1 122 ? 66.042 6.543 34.934 1.00 58.10 ? 312 ARG A CZ 1 ATOM 959 N NH1 . ARG A 1 122 ? 65.256 5.772 34.192 1.00 58.14 ? 312 ARG A NH1 1 ATOM 960 N NH2 . ARG A 1 122 ? 65.612 6.990 36.109 1.00 58.01 ? 312 ARG A NH2 1 ATOM 961 N N . SER A 1 123 ? 72.268 2.586 34.627 1.00 20.71 ? 313 SER A N 1 ATOM 962 C CA . SER A 1 123 ? 73.723 2.519 34.694 1.00 19.41 ? 313 SER A CA 1 ATOM 963 C C . SER A 1 123 ? 74.156 1.404 33.745 1.00 20.43 ? 313 SER A C 1 ATOM 964 O O . SER A 1 123 ? 74.920 0.509 34.113 1.00 20.80 ? 313 SER A O 1 ATOM 965 C CB . SER A 1 123 ? 74.185 2.210 36.119 1.00 14.14 ? 313 SER A CB 1 ATOM 966 O OG . SER A 1 123 ? 75.590 2.367 36.240 1.00 14.88 ? 313 SER A OG 1 ATOM 967 N N . THR A 1 124 ? 73.652 1.468 32.516 1.00 18.38 ? 314 THR A N 1 ATOM 968 C CA . THR A 1 124 ? 73.955 0.459 31.512 1.00 21.98 ? 314 THR A CA 1 ATOM 969 C C . THR A 1 124 ? 74.161 1.036 30.115 1.00 22.90 ? 314 THR A C 1 ATOM 970 O O . THR A 1 124 ? 73.955 2.229 29.877 1.00 24.05 ? 314 THR A O 1 ATOM 971 C CB . THR A 1 124 ? 72.827 -0.587 31.434 1.00 23.11 ? 314 THR A CB 1 ATOM 972 O OG1 . THR A 1 124 ? 71.563 0.084 31.353 1.00 21.69 ? 314 THR A OG1 1 ATOM 973 C CG2 . THR A 1 124 ? 72.847 -1.490 32.660 1.00 20.74 ? 314 THR A CG2 1 ATOM 974 N N . GLY A 1 125 ? 74.573 0.165 29.198 1.00 18.37 ? 315 GLY A N 1 ATOM 975 C CA . GLY A 1 125 ? 74.800 0.560 27.822 1.00 12.09 ? 315 GLY A CA 1 ATOM 976 C C . GLY A 1 125 ? 75.006 -0.681 26.976 1.00 13.62 ? 315 GLY A C 1 ATOM 977 O O . GLY A 1 125 ? 75.499 -1.690 27.477 1.00 13.73 ? 315 GLY A O 1 ATOM 978 N N . ILE A 1 126 ? 74.610 -0.635 25.708 1.00 11.67 ? 316 ILE A N 1 ATOM 979 C CA . ILE A 1 126 ? 74.809 -1.785 24.838 1.00 11.30 ? 316 ILE A CA 1 ATOM 980 C C . ILE A 1 126 ? 75.896 -1.440 23.829 1.00 11.42 ? 316 ILE A C 1 ATOM 981 O O . ILE A 1 126 ? 76.035 -0.287 23.425 1.00 13.17 ? 316 ILE A O 1 ATOM 982 C CB . ILE A 1 126 ? 73.517 -2.188 24.091 1.00 9.34 ? 316 ILE A CB 1 ATOM 983 C CG1 . ILE A 1 126 ? 73.115 -1.103 23.097 1.00 13.01 ? 316 ILE A CG1 1 ATOM 984 C CG2 . ILE A 1 126 ? 72.404 -2.429 25.088 1.00 5.09 ? 316 ILE A CG2 1 ATOM 985 C CD1 . ILE A 1 126 ? 71.970 -1.518 22.191 1.00 21.64 ? 316 ILE A CD1 1 ATOM 986 N N . ILE A 1 127 ? 76.663 -2.446 23.431 1.00 11.45 ? 317 ILE A N 1 ATOM 987 C CA . ILE A 1 127 ? 77.761 -2.258 22.497 1.00 9.55 ? 317 ILE A CA 1 ATOM 988 C C . ILE A 1 127 ? 77.763 -3.367 21.456 1.00 14.46 ? 317 ILE A C 1 ATOM 989 O O . ILE A 1 127 ? 77.519 -4.531 21.782 1.00 16.04 ? 317 ILE A O 1 ATOM 990 C CB . ILE A 1 127 ? 79.102 -2.295 23.255 1.00 13.46 ? 317 ILE A CB 1 ATOM 991 C CG1 . ILE A 1 127 ? 79.101 -1.222 24.346 1.00 13.58 ? 317 ILE A CG1 1 ATOM 992 C CG2 . ILE A 1 127 ? 80.265 -2.106 22.297 1.00 4.47 ? 317 ILE A CG2 1 ATOM 993 C CD1 . ILE A 1 127 ? 80.193 -1.408 25.369 1.00 20.61 ? 317 ILE A CD1 1 ATOM 994 N N . GLN A 1 128 ? 78.043 -3.009 20.206 1.00 17.27 ? 318 GLN A N 1 ATOM 995 C CA . GLN A 1 128 ? 78.090 -3.991 19.124 1.00 16.57 ? 318 GLN A CA 1 ATOM 996 C C . GLN A 1 128 ? 79.531 -4.416 18.861 1.00 15.38 ? 318 GLN A C 1 ATOM 997 O O . GLN A 1 128 ? 80.431 -3.579 18.864 1.00 12.53 ? 318 GLN A O 1 ATOM 998 C CB . GLN A 1 128 ? 77.489 -3.407 17.840 1.00 13.08 ? 318 GLN A CB 1 ATOM 999 C CG . GLN A 1 128 ? 77.674 -4.308 16.623 1.00 15.15 ? 318 GLN A CG 1 ATOM 1000 C CD . GLN A 1 128 ? 77.010 -3.772 15.364 1.00 14.48 ? 318 GLN A CD 1 ATOM 1001 O OE1 . GLN A 1 128 ? 77.180 -4.328 14.279 1.00 12.46 ? 318 GLN A OE1 1 ATOM 1002 N NE2 . GLN A 1 128 ? 76.248 -2.693 15.503 1.00 8.80 ? 318 GLN A NE2 1 ATOM 1003 N N . ASP A 1 129 ? 79.746 -5.714 18.643 1.00 16.49 ? 319 ASP A N 1 ATOM 1004 C CA . ASP A 1 129 ? 81.084 -6.232 18.363 1.00 17.53 ? 319 ASP A CA 1 ATOM 1005 C C . ASP A 1 129 ? 81.427 -5.844 16.924 1.00 20.44 ? 319 ASP A C 1 ATOM 1006 O O . ASP A 1 129 ? 81.676 -6.687 16.063 1.00 23.04 ? 319 ASP A O 1 ATOM 1007 C CB . ASP A 1 129 ? 81.116 -7.751 18.526 1.00 19.13 ? 319 ASP A CB 1 ATOM 1008 C CG . ASP A 1 129 ? 82.532 -8.298 18.626 1.00 26.91 ? 319 ASP A CG 1 ATOM 1009 O OD1 . ASP A 1 129 ? 82.698 -9.535 18.572 1.00 33.11 ? 319 ASP A OD1 1 ATOM 1010 O OD2 . ASP A 1 129 ? 83.480 -7.496 18.767 1.00 22.60 ? 319 ASP A OD2 1 ATOM 1011 N N . TYR A 1 130 ? 81.424 -4.535 16.703 1.00 23.67 ? 320 TYR A N 1 ATOM 1012 C CA . TYR A 1 130 ? 81.684 -3.881 15.427 1.00 22.08 ? 320 TYR A CA 1 ATOM 1013 C C . TYR A 1 130 ? 82.981 -4.264 14.703 1.00 22.42 ? 320 TYR A C 1 ATOM 1014 O O . TYR A 1 130 ? 83.029 -4.242 13.472 1.00 22.41 ? 320 TYR A O 1 ATOM 1015 C CB . TYR A 1 130 ? 81.641 -2.370 15.683 1.00 26.02 ? 320 TYR A CB 1 ATOM 1016 C CG . TYR A 1 130 ? 81.880 -1.462 14.503 1.00 29.13 ? 320 TYR A CG 1 ATOM 1017 C CD1 . TYR A 1 130 ? 81.045 -1.490 13.390 1.00 34.98 ? 320 TYR A CD1 1 ATOM 1018 C CD2 . TYR A 1 130 ? 82.905 -0.516 14.535 1.00 32.26 ? 320 TYR A CD2 1 ATOM 1019 C CE1 . TYR A 1 130 ? 81.220 -0.593 12.336 1.00 40.97 ? 320 TYR A CE1 1 ATOM 1020 C CE2 . TYR A 1 130 ? 83.091 0.383 13.492 1.00 37.16 ? 320 TYR A CE2 1 ATOM 1021 C CZ . TYR A 1 130 ? 82.245 0.341 12.395 1.00 42.74 ? 320 TYR A CZ 1 ATOM 1022 O OH . TYR A 1 130 ? 82.425 1.236 11.361 1.00 49.23 ? 320 TYR A OH 1 ATOM 1023 N N . SER A 1 131 ? 84.022 -4.625 15.450 1.00 18.97 ? 321 SER A N 1 ATOM 1024 C CA . SER A 1 131 ? 85.303 -4.962 14.833 1.00 13.26 ? 321 SER A CA 1 ATOM 1025 C C . SER A 1 131 ? 86.134 -6.000 15.575 1.00 17.49 ? 321 SER A C 1 ATOM 1026 O O . SER A 1 131 ? 85.920 -6.256 16.759 1.00 20.60 ? 321 SER A O 1 ATOM 1027 C CB . SER A 1 131 ? 86.134 -3.687 14.672 1.00 14.59 ? 321 SER A CB 1 ATOM 1028 O OG . SER A 1 131 ? 87.499 -3.985 14.427 1.00 12.18 ? 321 SER A OG 1 ATOM 1029 N N . GLU A 1 132 ? 87.092 -6.589 14.865 1.00 18.54 ? 322 GLU A N 1 ATOM 1030 C CA . GLU A 1 132 ? 87.986 -7.586 15.445 1.00 20.61 ? 322 GLU A CA 1 ATOM 1031 C C . GLU A 1 132 ? 89.154 -6.937 16.182 1.00 19.85 ? 322 GLU A C 1 ATOM 1032 O O . GLU A 1 132 ? 89.836 -7.588 16.969 1.00 25.16 ? 322 GLU A O 1 ATOM 1033 C CB . GLU A 1 132 ? 88.526 -8.521 14.360 1.00 24.71 ? 322 GLU A CB 1 ATOM 1034 C CG . GLU A 1 132 ? 87.750 -9.823 14.243 1.00 42.49 ? 322 GLU A CG 1 ATOM 1035 C CD . GLU A 1 132 ? 87.840 -10.670 15.506 1.00 49.99 ? 322 GLU A CD 1 ATOM 1036 O OE1 . GLU A 1 132 ? 87.077 -11.654 15.622 1.00 53.91 ? 322 GLU A OE1 1 ATOM 1037 O OE2 . GLU A 1 132 ? 88.679 -10.355 16.380 1.00 52.05 ? 322 GLU A OE2 1 ATOM 1038 N N . ILE A 1 133 ? 89.381 -5.653 15.919 1.00 15.42 ? 323 ILE A N 1 ATOM 1039 C CA . ILE A 1 133 ? 90.459 -4.913 16.561 1.00 10.73 ? 323 ILE A CA 1 ATOM 1040 C C . ILE A 1 133 ? 90.055 -4.521 17.983 1.00 14.63 ? 323 ILE A C 1 ATOM 1041 O O . ILE A 1 133 ? 89.319 -3.550 18.181 1.00 13.85 ? 323 ILE A O 1 ATOM 1042 C CB . ILE A 1 133 ? 90.779 -3.626 15.790 1.00 11.05 ? 323 ILE A CB 1 ATOM 1043 C CG1 . ILE A 1 133 ? 91.036 -3.947 14.319 1.00 4.69 ? 323 ILE A CG1 1 ATOM 1044 C CG2 . ILE A 1 133 ? 91.987 -2.948 16.405 1.00 7.94 ? 323 ILE A CG2 1 ATOM 1045 C CD1 . ILE A 1 133 ? 91.208 -2.711 13.458 1.00 10.57 ? 323 ILE A CD1 1 ATOM 1046 N N . ASN A 1 134 ? 90.549 -5.271 18.965 1.00 16.56 ? 324 ASN A N 1 ATOM 1047 C CA . ASN A 1 134 ? 90.235 -5.016 20.367 1.00 14.27 ? 324 ASN A CA 1 ATOM 1048 C C . ASN A 1 134 ? 90.109 -3.543 20.738 1.00 13.20 ? 324 ASN A C 1 ATOM 1049 O O . ASN A 1 134 ? 89.160 -3.155 21.416 1.00 16.21 ? 324 ASN A O 1 ATOM 1050 C CB . ASN A 1 134 ? 91.273 -5.680 21.272 1.00 12.23 ? 324 ASN A CB 1 ATOM 1051 C CG . ASN A 1 134 ? 91.142 -7.190 21.293 1.00 18.26 ? 324 ASN A CG 1 ATOM 1052 O OD1 . ASN A 1 134 ? 90.035 -7.721 21.311 1.00 21.39 ? 324 ASN A OD1 1 ATOM 1053 N ND2 . ASN A 1 134 ? 92.270 -7.888 21.308 1.00 22.16 ? 324 ASN A ND2 1 ATOM 1054 N N . LEU A 1 135 ? 91.053 -2.722 20.291 1.00 15.48 ? 325 LEU A N 1 ATOM 1055 C CA . LEU A 1 135 ? 91.020 -1.297 20.610 1.00 16.51 ? 325 LEU A CA 1 ATOM 1056 C C . LEU A 1 135 ? 89.737 -0.618 20.150 1.00 16.63 ? 325 LEU A C 1 ATOM 1057 O O . LEU A 1 135 ? 89.170 0.201 20.874 1.00 20.59 ? 325 LEU A O 1 ATOM 1058 C CB . LEU A 1 135 ? 92.230 -0.576 20.002 1.00 11.37 ? 325 LEU A CB 1 ATOM 1059 C CG . LEU A 1 135 ? 92.197 0.954 20.096 1.00 11.56 ? 325 LEU A CG 1 ATOM 1060 C CD1 . LEU A 1 135 ? 91.967 1.393 21.531 1.00 4.73 ? 325 LEU A CD1 1 ATOM 1061 C CD2 . LEU A 1 135 ? 93.498 1.523 19.562 1.00 12.41 ? 325 LEU A CD2 1 ATOM 1062 N N . VAL A 1 136 ? 89.277 -0.955 18.952 1.00 17.82 ? 326 VAL A N 1 ATOM 1063 C CA . VAL A 1 136 ? 88.057 -0.354 18.429 1.00 14.64 ? 326 VAL A CA 1 ATOM 1064 C C . VAL A 1 136 ? 86.875 -0.637 19.349 1.00 14.08 ? 326 VAL A C 1 ATOM 1065 O O . VAL A 1 136 ? 86.118 0.274 19.691 1.00 19.03 ? 326 VAL A O 1 ATOM 1066 C CB . VAL A 1 136 ? 87.738 -0.872 17.010 1.00 13.21 ? 326 VAL A CB 1 ATOM 1067 C CG1 . VAL A 1 136 ? 86.419 -0.311 16.537 1.00 1.00 ? 326 VAL A CG1 1 ATOM 1068 C CG2 . VAL A 1 136 ? 88.844 -0.461 16.050 1.00 14.44 ? 326 VAL A CG2 1 ATOM 1069 N N . VAL A 1 137 ? 86.719 -1.891 19.759 1.00 6.86 ? 327 VAL A N 1 ATOM 1070 C CA . VAL A 1 137 ? 85.613 -2.248 20.640 1.00 10.15 ? 327 VAL A CA 1 ATOM 1071 C C . VAL A 1 137 ? 85.796 -1.618 22.018 1.00 15.48 ? 327 VAL A C 1 ATOM 1072 O O . VAL A 1 137 ? 84.830 -1.158 22.632 1.00 15.84 ? 327 VAL A O 1 ATOM 1073 C CB . VAL A 1 137 ? 85.471 -3.785 20.788 1.00 9.00 ? 327 VAL A CB 1 ATOM 1074 C CG1 . VAL A 1 137 ? 84.354 -4.120 21.770 1.00 1.00 ? 327 VAL A CG1 1 ATOM 1075 C CG2 . VAL A 1 137 ? 85.165 -4.407 19.430 1.00 1.00 ? 327 VAL A CG2 1 ATOM 1076 N N . ALA A 1 138 ? 87.036 -1.590 22.499 1.00 16.30 ? 328 ALA A N 1 ATOM 1077 C CA . ALA A 1 138 ? 87.321 -1.002 23.802 1.00 13.95 ? 328 ALA A CA 1 ATOM 1078 C C . ALA A 1 138 ? 86.888 0.459 23.793 1.00 16.22 ? 328 ALA A C 1 ATOM 1079 O O . ALA A 1 138 ? 86.246 0.932 24.734 1.00 16.24 ? 328 ALA A O 1 ATOM 1080 C CB . ALA A 1 138 ? 88.804 -1.112 24.118 1.00 12.60 ? 328 ALA A CB 1 ATOM 1081 N N . VAL A 1 139 ? 87.232 1.172 22.724 1.00 15.07 ? 329 VAL A N 1 ATOM 1082 C CA . VAL A 1 139 ? 86.857 2.579 22.611 1.00 15.12 ? 329 VAL A CA 1 ATOM 1083 C C . VAL A 1 139 ? 85.338 2.739 22.652 1.00 14.42 ? 329 VAL A C 1 ATOM 1084 O O . VAL A 1 139 ? 84.833 3.637 23.319 1.00 15.08 ? 329 VAL A O 1 ATOM 1085 C CB . VAL A 1 139 ? 87.408 3.216 21.307 1.00 16.44 ? 329 VAL A CB 1 ATOM 1086 C CG1 . VAL A 1 139 ? 86.927 4.654 21.181 1.00 2.92 ? 329 VAL A CG1 1 ATOM 1087 C CG2 . VAL A 1 139 ? 88.933 3.181 21.317 1.00 13.72 ? 329 VAL A CG2 1 ATOM 1088 N N . ILE A 1 140 ? 84.609 1.872 21.951 1.00 12.99 ? 330 ILE A N 1 ATOM 1089 C CA . ILE A 1 140 ? 83.148 1.951 21.956 1.00 14.74 ? 330 ILE A CA 1 ATOM 1090 C C . ILE A 1 140 ? 82.626 1.722 23.377 1.00 14.65 ? 330 ILE A C 1 ATOM 1091 O O . ILE A 1 140 ? 81.723 2.418 23.842 1.00 14.50 ? 330 ILE A O 1 ATOM 1092 C CB . ILE A 1 140 ? 82.499 0.894 21.014 1.00 15.31 ? 330 ILE A CB 1 ATOM 1093 C CG1 . ILE A 1 140 ? 82.885 1.171 19.561 1.00 14.73 ? 330 ILE A CG1 1 ATOM 1094 C CG2 . ILE A 1 140 ? 80.983 0.938 21.142 1.00 4.26 ? 330 ILE A CG2 1 ATOM 1095 C CD1 . ILE A 1 140 ? 82.354 0.150 18.582 1.00 9.65 ? 330 ILE A CD1 1 ATOM 1096 N N . MET A 1 141 ? 83.204 0.742 24.060 1.00 16.66 ? 331 MET A N 1 ATOM 1097 C CA . MET A 1 141 ? 82.810 0.418 25.424 1.00 17.20 ? 331 MET A CA 1 ATOM 1098 C C . MET A 1 141 ? 83.012 1.646 26.316 1.00 20.07 ? 331 MET A C 1 ATOM 1099 O O . MET A 1 141 ? 82.102 2.054 27.043 1.00 20.74 ? 331 MET A O 1 ATOM 1100 C CB . MET A 1 141 ? 83.649 -0.759 25.928 1.00 21.25 ? 331 MET A CB 1 ATOM 1101 C CG . MET A 1 141 ? 83.085 -1.489 27.136 1.00 28.94 ? 331 MET A CG 1 ATOM 1102 S SD . MET A 1 141 ? 83.949 -3.063 27.437 1.00 28.35 ? 331 MET A SD 1 ATOM 1103 C CE . MET A 1 141 ? 83.367 -4.027 26.056 1.00 20.68 ? 331 MET A CE 1 ATOM 1104 N N . ALA A 1 142 ? 84.201 2.240 26.242 1.00 16.99 ? 332 ALA A N 1 ATOM 1105 C CA . ALA A 1 142 ? 84.523 3.427 27.032 1.00 15.21 ? 332 ALA A CA 1 ATOM 1106 C C . ALA A 1 142 ? 83.557 4.560 26.713 1.00 16.79 ? 332 ALA A C 1 ATOM 1107 O O . ALA A 1 142 ? 83.026 5.213 27.614 1.00 15.32 ? 332 ALA A O 1 ATOM 1108 C CB . ALA A 1 142 ? 85.952 3.874 26.746 1.00 15.64 ? 332 ALA A CB 1 ATOM 1109 N N . HIS A 1 143 ? 83.346 4.784 25.418 1.00 17.41 ? 333 HIS A N 1 ATOM 1110 C CA . HIS A 1 143 ? 82.452 5.827 24.930 1.00 15.37 ? 333 HIS A CA 1 ATOM 1111 C C . HIS A 1 143 ? 81.074 5.704 25.577 1.00 20.39 ? 333 HIS A C 1 ATOM 1112 O O . HIS A 1 143 ? 80.523 6.688 26.072 1.00 24.74 ? 333 HIS A O 1 ATOM 1113 C CB . HIS A 1 143 ? 82.318 5.718 23.410 1.00 13.36 ? 333 HIS A CB 1 ATOM 1114 C CG . HIS A 1 143 ? 81.449 6.772 22.795 1.00 13.28 ? 333 HIS A CG 1 ATOM 1115 N ND1 . HIS A 1 143 ? 81.962 7.887 22.167 1.00 7.67 ? 333 HIS A ND1 1 ATOM 1116 C CD2 . HIS A 1 143 ? 80.101 6.871 22.698 1.00 7.48 ? 333 HIS A CD2 1 ATOM 1117 C CE1 . HIS A 1 143 ? 80.967 8.626 21.707 1.00 7.65 ? 333 HIS A CE1 1 ATOM 1118 N NE2 . HIS A 1 143 ? 79.828 8.032 22.016 1.00 6.58 ? 333 HIS A NE2 1 ATOM 1119 N N . GLU A 1 144 ? 80.521 4.494 25.574 1.00 19.15 ? 334 GLU A N 1 ATOM 1120 C CA . GLU A 1 144 ? 79.206 4.274 26.159 1.00 20.35 ? 334 GLU A CA 1 ATOM 1121 C C . GLU A 1 144 ? 79.204 4.480 27.671 1.00 20.78 ? 334 GLU A C 1 ATOM 1122 O O . GLU A 1 144 ? 78.226 4.977 28.233 1.00 20.29 ? 334 GLU A O 1 ATOM 1123 C CB . GLU A 1 144 ? 78.691 2.875 25.808 1.00 17.08 ? 334 GLU A CB 1 ATOM 1124 C CG . GLU A 1 144 ? 78.378 2.683 24.329 1.00 17.62 ? 334 GLU A CG 1 ATOM 1125 C CD . GLU A 1 144 ? 77.623 3.856 23.735 1.00 19.21 ? 334 GLU A CD 1 ATOM 1126 O OE1 . GLU A 1 144 ? 76.768 4.427 24.440 1.00 24.52 ? 334 GLU A OE1 1 ATOM 1127 O OE2 . GLU A 1 144 ? 77.877 4.204 22.563 1.00 22.82 ? 334 GLU A OE2 1 ATOM 1128 N N . MET A 1 145 ? 80.288 4.093 28.335 1.00 22.37 ? 335 MET A N 1 ATOM 1129 C CA . MET A 1 145 ? 80.377 4.291 29.777 1.00 23.63 ? 335 MET A CA 1 ATOM 1130 C C . MET A 1 145 ? 80.495 5.789 30.028 1.00 22.89 ? 335 MET A C 1 ATOM 1131 O O . MET A 1 145 ? 80.049 6.296 31.057 1.00 21.56 ? 335 MET A O 1 ATOM 1132 C CB . MET A 1 145 ? 81.595 3.568 30.357 1.00 22.17 ? 335 MET A CB 1 ATOM 1133 C CG . MET A 1 145 ? 81.350 2.103 30.671 1.00 30.74 ? 335 MET A CG 1 ATOM 1134 S SD . MET A 1 145 ? 82.750 1.324 31.498 1.00 39.65 ? 335 MET A SD 1 ATOM 1135 C CE . MET A 1 145 ? 82.948 2.418 32.917 1.00 29.46 ? 335 MET A CE 1 ATOM 1136 N N . GLY A 1 146 ? 81.096 6.489 29.069 1.00 22.06 ? 336 GLY A N 1 ATOM 1137 C CA . GLY A 1 146 ? 81.255 7.926 29.180 1.00 18.41 ? 336 GLY A CA 1 ATOM 1138 C C . GLY A 1 146 ? 79.900 8.587 29.319 1.00 21.70 ? 336 GLY A C 1 ATOM 1139 O O . GLY A 1 146 ? 79.681 9.382 30.233 1.00 26.65 ? 336 GLY A O 1 ATOM 1140 N N . HIS A 1 147 ? 78.982 8.267 28.412 1.00 17.84 ? 337 HIS A N 1 ATOM 1141 C CA . HIS A 1 147 ? 77.649 8.840 28.483 1.00 13.80 ? 337 HIS A CA 1 ATOM 1142 C C . HIS A 1 147 ? 77.093 8.571 29.869 1.00 17.16 ? 337 HIS A C 1 ATOM 1143 O O . HIS A 1 147 ? 76.438 9.429 30.454 1.00 23.72 ? 337 HIS A O 1 ATOM 1144 C CB . HIS A 1 147 ? 76.725 8.226 27.427 1.00 11.96 ? 337 HIS A CB 1 ATOM 1145 C CG . HIS A 1 147 ? 77.016 8.678 26.029 1.00 15.89 ? 337 HIS A CG 1 ATOM 1146 N ND1 . HIS A 1 147 ? 77.164 10.007 25.691 1.00 17.97 ? 337 HIS A ND1 1 ATOM 1147 C CD2 . HIS A 1 147 ? 77.163 7.980 24.878 1.00 12.29 ? 337 HIS A CD2 1 ATOM 1148 C CE1 . HIS A 1 147 ? 77.390 10.107 24.393 1.00 12.73 ? 337 HIS A CE1 1 ATOM 1149 N NE2 . HIS A 1 147 ? 77.394 8.892 23.876 1.00 8.98 ? 337 HIS A NE2 1 ATOM 1150 N N . ASN A 1 148 ? 77.360 7.378 30.395 1.00 18.65 ? 338 ASN A N 1 ATOM 1151 C CA . ASN A 1 148 ? 76.885 7.010 31.727 1.00 23.23 ? 338 ASN A CA 1 ATOM 1152 C C . ASN A 1 148 ? 77.431 7.982 32.775 1.00 25.98 ? 338 ASN A C 1 ATOM 1153 O O . ASN A 1 148 ? 76.736 8.353 33.726 1.00 26.49 ? 338 ASN A O 1 ATOM 1154 C CB . ASN A 1 148 ? 77.318 5.581 32.074 1.00 22.43 ? 338 ASN A CB 1 ATOM 1155 C CG . ASN A 1 148 ? 76.453 4.523 31.407 1.00 27.55 ? 338 ASN A CG 1 ATOM 1156 O OD1 . ASN A 1 148 ? 76.714 3.324 31.533 1.00 22.07 ? 338 ASN A OD1 1 ATOM 1157 N ND2 . ASN A 1 148 ? 75.415 4.961 30.701 1.00 25.59 ? 338 ASN A ND2 1 ATOM 1158 N N . LEU A 1 149 ? 78.683 8.389 32.589 1.00 23.69 ? 339 LEU A N 1 ATOM 1159 C CA . LEU A 1 149 ? 79.339 9.317 33.501 1.00 21.40 ? 339 LEU A CA 1 ATOM 1160 C C . LEU A 1 149 ? 79.011 10.764 33.140 1.00 21.17 ? 339 LEU A C 1 ATOM 1161 O O . LEU A 1 149 ? 79.832 11.664 33.326 1.00 22.40 ? 339 LEU A O 1 ATOM 1162 C CB . LEU A 1 149 ? 80.855 9.099 33.466 1.00 18.07 ? 339 LEU A CB 1 ATOM 1163 C CG . LEU A 1 149 ? 81.347 7.785 34.075 1.00 14.91 ? 339 LEU A CG 1 ATOM 1164 C CD1 . LEU A 1 149 ? 82.824 7.611 33.810 1.00 13.61 ? 339 LEU A CD1 1 ATOM 1165 C CD2 . LEU A 1 149 ? 81.066 7.789 35.570 1.00 18.79 ? 339 LEU A CD2 1 ATOM 1166 N N . GLY A 1 150 ? 77.807 10.974 32.616 1.00 18.89 ? 340 GLY A N 1 ATOM 1167 C CA . GLY A 1 150 ? 77.379 12.308 32.239 1.00 20.88 ? 340 GLY A CA 1 ATOM 1168 C C . GLY A 1 150 ? 78.227 12.999 31.183 1.00 23.94 ? 340 GLY A C 1 ATOM 1169 O O . GLY A 1 150 ? 78.222 14.228 31.094 1.00 21.58 ? 340 GLY A O 1 ATOM 1170 N N . ILE A 1 151 ? 78.955 12.229 30.379 1.00 21.92 ? 341 ILE A N 1 ATOM 1171 C CA . ILE A 1 151 ? 79.789 12.825 29.340 1.00 24.29 ? 341 ILE A CA 1 ATOM 1172 C C . ILE A 1 151 ? 79.056 12.837 27.999 1.00 21.75 ? 341 ILE A C 1 ATOM 1173 O O . ILE A 1 151 ? 78.348 11.889 27.657 1.00 17.25 ? 341 ILE A O 1 ATOM 1174 C CB . ILE A 1 151 ? 81.126 12.061 29.164 1.00 23.09 ? 341 ILE A CB 1 ATOM 1175 C CG1 . ILE A 1 151 ? 81.774 11.805 30.525 1.00 24.82 ? 341 ILE A CG1 1 ATOM 1176 C CG2 . ILE A 1 151 ? 82.081 12.883 28.317 1.00 20.95 ? 341 ILE A CG2 1 ATOM 1177 C CD1 . ILE A 1 151 ? 83.103 11.081 30.437 1.00 19.66 ? 341 ILE A CD1 1 ATOM 1178 N N . ASN A 1 152 ? 79.224 13.921 27.249 1.00 19.49 ? 342 ASN A N 1 ATOM 1179 C CA . ASN A 1 152 ? 78.582 14.049 25.948 1.00 22.69 ? 342 ASN A CA 1 ATOM 1180 C C . ASN A 1 152 ? 79.617 14.109 24.828 1.00 23.51 ? 342 ASN A C 1 ATOM 1181 O O . ASN A 1 152 ? 80.821 14.183 25.079 1.00 25.70 ? 342 ASN A O 1 ATOM 1182 C CB . ASN A 1 152 ? 77.684 15.290 25.912 1.00 24.24 ? 342 ASN A CB 1 ATOM 1183 C CG . ASN A 1 152 ? 76.402 15.109 26.722 1.00 32.29 ? 342 ASN A CG 1 ATOM 1184 O OD1 . ASN A 1 152 ? 75.549 14.283 26.385 1.00 31.73 ? 342 ASN A OD1 1 ATOM 1185 N ND2 . ASN A 1 152 ? 76.265 15.883 27.795 1.00 28.60 ? 342 ASN A ND2 1 ATOM 1186 N N . HIS A 1 153 ? 79.135 14.070 23.591 1.00 19.79 ? 343 HIS A N 1 ATOM 1187 C CA . HIS A 1 153 ? 80.002 14.089 22.422 1.00 19.21 ? 343 HIS A CA 1 ATOM 1188 C C . HIS A 1 153 ? 80.852 15.339 22.295 1.00 17.12 ? 343 HIS A C 1 ATOM 1189 O O . HIS A 1 153 ? 80.470 16.415 22.752 1.00 17.94 ? 343 HIS A O 1 ATOM 1190 C CB . HIS A 1 153 ? 79.158 13.910 21.159 1.00 20.98 ? 343 HIS A CB 1 ATOM 1191 C CG . HIS A 1 153 ? 78.552 12.549 21.032 1.00 23.52 ? 343 HIS A CG 1 ATOM 1192 N ND1 . HIS A 1 153 ? 77.405 12.309 20.309 1.00 21.56 ? 343 HIS A ND1 1 ATOM 1193 C CD2 . HIS A 1 153 ? 78.945 11.350 21.523 1.00 25.08 ? 343 HIS A CD2 1 ATOM 1194 C CE1 . HIS A 1 153 ? 77.116 11.022 20.361 1.00 26.09 ? 343 HIS A CE1 1 ATOM 1195 N NE2 . HIS A 1 153 ? 78.035 10.418 21.092 1.00 24.41 ? 343 HIS A NE2 1 ATOM 1196 N N . ASP A 1 154 ? 82.015 15.187 21.670 1.00 14.03 ? 344 ASP A N 1 ATOM 1197 C CA . ASP A 1 154 ? 82.909 16.311 21.465 1.00 20.76 ? 344 ASP A CA 1 ATOM 1198 C C . ASP A 1 154 ? 82.385 17.200 20.342 1.00 23.76 ? 344 ASP A C 1 ATOM 1199 O O . ASP A 1 154 ? 81.599 16.769 19.498 1.00 23.55 ? 344 ASP A O 1 ATOM 1200 C CB . ASP A 1 154 ? 84.320 15.830 21.115 1.00 20.29 ? 344 ASP A CB 1 ATOM 1201 C CG . ASP A 1 154 ? 84.998 15.117 22.268 1.00 24.74 ? 344 ASP A CG 1 ATOM 1202 O OD1 . ASP A 1 154 ? 84.754 15.498 23.433 1.00 27.86 ? 344 ASP A OD1 1 ATOM 1203 O OD2 . ASP A 1 154 ? 85.790 14.189 22.008 1.00 20.62 ? 344 ASP A OD2 1 ATOM 1204 N N . SER A 1 155 ? 82.825 18.449 20.343 1.00 26.84 ? 345 SER A N 1 ATOM 1205 C CA . SER A 1 155 ? 82.417 19.398 19.323 1.00 29.33 ? 345 SER A CA 1 ATOM 1206 C C . SER A 1 155 ? 83.370 20.574 19.380 1.00 28.61 ? 345 SER A C 1 ATOM 1207 O O . SER A 1 155 ? 84.199 20.665 20.286 1.00 29.88 ? 345 SER A O 1 ATOM 1208 C CB . SER A 1 155 ? 80.984 19.873 19.573 1.00 27.35 ? 345 SER A CB 1 ATOM 1209 O OG . SER A 1 155 ? 80.876 20.526 20.823 1.00 28.00 ? 345 SER A OG 1 ATOM 1210 N N . GLY A 1 156 ? 83.256 21.470 18.408 1.00 28.83 ? 346 GLY A N 1 ATOM 1211 C CA . GLY A 1 156 ? 84.125 22.628 18.382 1.00 26.92 ? 346 GLY A CA 1 ATOM 1212 C C . GLY A 1 156 ? 85.580 22.286 18.639 1.00 26.62 ? 346 GLY A C 1 ATOM 1213 O O . GLY A 1 156 ? 86.094 21.271 18.169 1.00 28.31 ? 346 GLY A O 1 ATOM 1214 N N . TYR A 1 157 ? 86.241 23.130 19.418 1.00 27.88 ? 347 TYR A N 1 ATOM 1215 C CA . TYR A 1 157 ? 87.650 22.946 19.713 1.00 24.95 ? 347 TYR A CA 1 ATOM 1216 C C . TYR A 1 157 ? 88.005 22.022 20.876 1.00 23.74 ? 347 TYR A C 1 ATOM 1217 O O . TYR A 1 157 ? 88.928 22.310 21.639 1.00 23.48 ? 347 TYR A O 1 ATOM 1218 C CB . TYR A 1 157 ? 88.308 24.317 19.909 1.00 22.43 ? 347 TYR A CB 1 ATOM 1219 C CG . TYR A 1 157 ? 88.359 25.129 18.635 1.00 21.38 ? 347 TYR A CG 1 ATOM 1220 C CD1 . TYR A 1 157 ? 87.204 25.696 18.094 1.00 23.44 ? 347 TYR A CD1 1 ATOM 1221 C CD2 . TYR A 1 157 ? 89.552 25.272 17.931 1.00 22.94 ? 347 TYR A CD2 1 ATOM 1222 C CE1 . TYR A 1 157 ? 87.239 26.377 16.878 1.00 19.93 ? 347 TYR A CE1 1 ATOM 1223 C CE2 . TYR A 1 157 ? 89.598 25.950 16.719 1.00 18.90 ? 347 TYR A CE2 1 ATOM 1224 C CZ . TYR A 1 157 ? 88.442 26.496 16.197 1.00 20.25 ? 347 TYR A CZ 1 ATOM 1225 O OH . TYR A 1 157 ? 88.494 27.137 14.981 1.00 22.05 ? 347 TYR A OH 1 ATOM 1226 N N . CYS A 1 158 ? 87.276 20.920 21.023 1.00 23.23 ? 348 CYS A N 1 ATOM 1227 C CA . CYS A 1 158 ? 87.598 19.964 22.079 1.00 24.38 ? 348 CYS A CA 1 ATOM 1228 C C . CYS A 1 158 ? 88.744 19.133 21.514 1.00 23.20 ? 348 CYS A C 1 ATOM 1229 O O . CYS A 1 158 ? 88.659 18.662 20.382 1.00 20.61 ? 348 CYS A O 1 ATOM 1230 C CB . CYS A 1 158 ? 86.411 19.047 22.394 1.00 25.16 ? 348 CYS A CB 1 ATOM 1231 S SG . CYS A 1 158 ? 85.001 19.843 23.233 1.00 33.63 ? 348 CYS A SG 1 ATOM 1232 N N . SER A 1 159 ? 89.820 18.961 22.278 1.00 22.29 ? 349 SER A N 1 ATOM 1233 C CA . SER A 1 159 ? 90.943 18.179 21.774 1.00 22.80 ? 349 SER A CA 1 ATOM 1234 C C . SER A 1 159 ? 91.545 17.208 22.777 1.00 21.65 ? 349 SER A C 1 ATOM 1235 O O . SER A 1 159 ? 91.245 17.241 23.972 1.00 20.30 ? 349 SER A O 1 ATOM 1236 C CB . SER A 1 159 ? 92.052 19.099 21.236 1.00 21.87 ? 349 SER A CB 1 ATOM 1237 O OG . SER A 1 159 ? 92.731 19.775 22.281 1.00 20.11 ? 349 SER A OG 1 ATOM 1238 N N . CYS A 1 160 ? 92.400 16.341 22.251 1.00 21.82 ? 350 CYS A N 1 ATOM 1239 C CA . CYS A 1 160 ? 93.104 15.325 23.019 1.00 27.05 ? 350 CYS A CA 1 ATOM 1240 C C . CYS A 1 160 ? 94.392 15.098 22.232 1.00 30.23 ? 350 CYS A C 1 ATOM 1241 O O . CYS A 1 160 ? 94.940 13.996 22.207 1.00 30.83 ? 350 CYS A O 1 ATOM 1242 C CB . CYS A 1 160 ? 92.274 14.031 23.074 1.00 27.62 ? 350 CYS A CB 1 ATOM 1243 S SG . CYS A 1 160 ? 91.863 13.321 21.440 1.00 28.96 ? 350 CYS A SG 1 ATOM 1244 N N . GLY A 1 161 ? 94.864 16.166 21.593 1.00 32.07 ? 351 GLY A N 1 ATOM 1245 C CA . GLY A 1 161 ? 96.057 16.086 20.771 1.00 34.83 ? 351 GLY A CA 1 ATOM 1246 C C . GLY A 1 161 ? 95.575 15.850 19.353 1.00 39.44 ? 351 GLY A C 1 ATOM 1247 O O . GLY A 1 161 ? 94.372 15.937 19.099 1.00 40.35 ? 351 GLY A O 1 ATOM 1248 N N . ASP A 1 162 ? 96.479 15.560 18.424 1.00 43.52 ? 352 ASP A N 1 ATOM 1249 C CA . ASP A 1 162 ? 96.055 15.308 17.049 1.00 50.45 ? 352 ASP A CA 1 ATOM 1250 C C . ASP A 1 162 ? 95.552 13.868 16.928 1.00 50.01 ? 352 ASP A C 1 ATOM 1251 O O . ASP A 1 162 ? 95.949 13.127 16.025 1.00 49.33 ? 352 ASP A O 1 ATOM 1252 C CB . ASP A 1 162 ? 97.209 15.550 16.063 1.00 55.48 ? 352 ASP A CB 1 ATOM 1253 C CG . ASP A 1 162 ? 98.373 14.596 16.269 1.00 59.43 ? 352 ASP A CG 1 ATOM 1254 O OD1 . ASP A 1 162 ? 99.295 14.597 15.424 1.00 55.67 ? 352 ASP A OD1 1 ATOM 1255 O OD2 . ASP A 1 162 ? 98.369 13.850 17.272 1.00 63.28 ? 352 ASP A OD2 1 ATOM 1256 N N . TYR A 1 163 ? 94.672 13.486 17.851 1.00 46.31 ? 353 TYR A N 1 ATOM 1257 C CA . TYR A 1 163 ? 94.110 12.139 17.880 1.00 41.70 ? 353 TYR A CA 1 ATOM 1258 C C . TYR A 1 163 ? 92.590 12.163 17.969 1.00 37.64 ? 353 TYR A C 1 ATOM 1259 O O . TYR A 1 163 ? 92.003 13.090 18.528 1.00 38.63 ? 353 TYR A O 1 ATOM 1260 C CB . TYR A 1 163 ? 94.658 11.367 19.082 1.00 42.55 ? 353 TYR A CB 1 ATOM 1261 C CG . TYR A 1 163 ? 96.163 11.276 19.133 1.00 44.34 ? 353 TYR A CG 1 ATOM 1262 C CD1 . TYR A 1 163 ? 96.867 10.523 18.199 1.00 45.63 ? 353 TYR A CD1 1 ATOM 1263 C CD2 . TYR A 1 163 ? 96.887 11.951 20.118 1.00 45.56 ? 353 TYR A CD2 1 ATOM 1264 C CE1 . TYR A 1 163 ? 98.259 10.442 18.241 1.00 48.80 ? 353 TYR A CE1 1 ATOM 1265 C CE2 . TYR A 1 163 ? 98.279 11.877 20.169 1.00 44.52 ? 353 TYR A CE2 1 ATOM 1266 C CZ . TYR A 1 163 ? 98.957 11.122 19.227 1.00 44.71 ? 353 TYR A CZ 1 ATOM 1267 O OH . TYR A 1 163 ? 100.330 11.054 19.260 1.00 43.98 ? 353 TYR A OH 1 ATOM 1268 N N . ALA A 1 164 ? 91.962 11.132 17.413 1.00 33.09 ? 354 ALA A N 1 ATOM 1269 C CA . ALA A 1 164 ? 90.514 11.001 17.443 1.00 26.21 ? 354 ALA A CA 1 ATOM 1270 C C . ALA A 1 164 ? 90.151 10.626 18.875 1.00 25.53 ? 354 ALA A C 1 ATOM 1271 O O . ALA A 1 164 ? 90.468 9.529 19.330 1.00 26.88 ? 354 ALA A O 1 ATOM 1272 C CB . ALA A 1 164 ? 90.079 9.912 16.485 1.00 27.23 ? 354 ALA A CB 1 ATOM 1273 N N . CYS A 1 165 ? 89.488 11.534 19.583 1.00 22.36 ? 355 CYS A N 1 ATOM 1274 C CA . CYS A 1 165 ? 89.130 11.294 20.977 1.00 21.66 ? 355 CYS A CA 1 ATOM 1275 C C . CYS A 1 165 ? 87.937 10.362 21.167 1.00 20.67 ? 355 CYS A C 1 ATOM 1276 O O . CYS A 1 165 ? 87.078 10.242 20.296 1.00 20.59 ? 355 CYS A O 1 ATOM 1277 C CB . CYS A 1 165 ? 88.882 12.631 21.675 1.00 23.78 ? 355 CYS A CB 1 ATOM 1278 S SG . CYS A 1 165 ? 89.969 13.958 21.056 1.00 31.94 ? 355 CYS A SG 1 ATOM 1279 N N . ILE A 1 166 ? 87.898 9.708 22.325 1.00 22.98 ? 356 ILE A N 1 ATOM 1280 C CA . ILE A 1 166 ? 86.845 8.754 22.668 1.00 21.68 ? 356 ILE A CA 1 ATOM 1281 C C . ILE A 1 166 ? 85.403 9.246 22.534 1.00 20.46 ? 356 ILE A C 1 ATOM 1282 O O . ILE A 1 166 ? 84.529 8.486 22.120 1.00 16.53 ? 356 ILE A O 1 ATOM 1283 C CB . ILE A 1 166 ? 87.039 8.207 24.115 1.00 19.84 ? 356 ILE A CB 1 ATOM 1284 C CG1 . ILE A 1 166 ? 88.174 7.181 24.150 1.00 23.42 ? 356 ILE A CG1 1 ATOM 1285 C CG2 . ILE A 1 166 ? 85.771 7.514 24.594 1.00 21.36 ? 356 ILE A CG2 1 ATOM 1286 C CD1 . ILE A 1 166 ? 89.514 7.712 23.761 1.00 25.66 ? 356 ILE A CD1 1 ATOM 1287 N N . MET A 1 167 ? 85.140 10.503 22.874 1.00 18.91 ? 357 MET A N 1 ATOM 1288 C CA . MET A 1 167 ? 83.771 10.997 22.794 1.00 19.35 ? 357 MET A CA 1 ATOM 1289 C C . MET A 1 167 ? 83.355 11.724 21.517 1.00 21.65 ? 357 MET A C 1 ATOM 1290 O O . MET A 1 167 ? 82.614 12.702 21.566 1.00 24.83 ? 357 MET A O 1 ATOM 1291 C CB . MET A 1 167 ? 83.450 11.866 24.015 1.00 11.47 ? 357 MET A CB 1 ATOM 1292 C CG . MET A 1 167 ? 83.461 11.095 25.323 1.00 11.81 ? 357 MET A CG 1 ATOM 1293 S SD . MET A 1 167 ? 82.661 9.466 25.189 1.00 18.81 ? 357 MET A SD 1 ATOM 1294 C CE . MET A 1 167 ? 80.910 9.943 25.116 1.00 23.92 ? 357 MET A CE 1 ATOM 1295 N N . ARG A 1 168 ? 83.827 11.242 20.372 1.00 24.89 ? 358 ARG A N 1 ATOM 1296 C CA . ARG A 1 168 ? 83.448 11.828 19.090 1.00 27.17 ? 358 ARG A CA 1 ATOM 1297 C C . ARG A 1 168 ? 82.094 11.234 18.695 1.00 26.53 ? 358 ARG A C 1 ATOM 1298 O O . ARG A 1 168 ? 81.768 10.114 19.085 1.00 29.85 ? 358 ARG A O 1 ATOM 1299 C CB . ARG A 1 168 ? 84.483 11.484 18.016 1.00 27.22 ? 358 ARG A CB 1 ATOM 1300 C CG . ARG A 1 168 ? 85.557 12.535 17.793 1.00 32.80 ? 358 ARG A CG 1 ATOM 1301 C CD . ARG A 1 168 ? 86.547 12.053 16.738 1.00 42.30 ? 358 ARG A CD 1 ATOM 1302 N NE . ARG A 1 168 ? 87.400 13.120 16.219 1.00 46.96 ? 358 ARG A NE 1 ATOM 1303 C CZ . ARG A 1 168 ? 88.197 13.878 16.967 1.00 50.89 ? 358 ARG A CZ 1 ATOM 1304 N NH1 . ARG A 1 168 ? 88.255 13.694 18.278 1.00 55.11 ? 358 ARG A NH1 1 ATOM 1305 N NH2 . ARG A 1 168 ? 88.941 14.818 16.400 1.00 51.35 ? 358 ARG A NH2 1 ATOM 1306 N N . PRO A 1 169 ? 81.286 11.974 17.922 1.00 26.35 ? 359 PRO A N 1 ATOM 1307 C CA . PRO A 1 169 ? 79.978 11.447 17.514 1.00 24.89 ? 359 PRO A CA 1 ATOM 1308 C C . PRO A 1 169 ? 80.047 10.037 16.910 1.00 25.40 ? 359 PRO A C 1 ATOM 1309 O O . PRO A 1 169 ? 79.205 9.191 17.207 1.00 29.51 ? 359 PRO A O 1 ATOM 1310 C CB . PRO A 1 169 ? 79.464 12.506 16.533 1.00 20.59 ? 359 PRO A CB 1 ATOM 1311 C CG . PRO A 1 169 ? 80.714 13.220 16.077 1.00 25.06 ? 359 PRO A CG 1 ATOM 1312 C CD . PRO A 1 169 ? 81.522 13.302 17.334 1.00 24.38 ? 359 PRO A CD 1 ATOM 1313 N N . GLU A 1 170 ? 81.036 9.780 16.061 1.00 23.62 ? 360 GLU A N 1 ATOM 1314 C CA . GLU A 1 170 ? 81.184 8.444 15.487 1.00 28.43 ? 360 GLU A CA 1 ATOM 1315 C C . GLU A 1 170 ? 82.618 7.922 15.591 1.00 26.15 ? 360 GLU A C 1 ATOM 1316 O O . GLU A 1 170 ? 83.582 8.661 15.400 1.00 28.89 ? 360 GLU A O 1 ATOM 1317 C CB . GLU A 1 170 ? 80.702 8.393 14.026 1.00 29.65 ? 360 GLU A CB 1 ATOM 1318 C CG . GLU A 1 170 ? 80.996 9.607 13.172 1.00 34.93 ? 360 GLU A CG 1 ATOM 1319 C CD . GLU A 1 170 ? 79.923 10.673 13.289 1.00 39.97 ? 360 GLU A CD 1 ATOM 1320 O OE1 . GLU A 1 170 ? 78.726 10.325 13.196 1.00 33.33 ? 360 GLU A OE1 1 ATOM 1321 O OE2 . GLU A 1 170 ? 80.274 11.858 13.462 1.00 43.34 ? 360 GLU A OE2 1 ATOM 1322 N N . ILE A 1 171 ? 82.745 6.637 15.901 1.00 24.18 ? 361 ILE A N 1 ATOM 1323 C CA . ILE A 1 171 ? 84.048 6.004 16.058 1.00 24.14 ? 361 ILE A CA 1 ATOM 1324 C C . ILE A 1 171 ? 84.969 6.180 14.855 1.00 21.52 ? 361 ILE A C 1 ATOM 1325 O O . ILE A 1 171 ? 84.544 6.061 13.707 1.00 24.49 ? 361 ILE A O 1 ATOM 1326 C CB . ILE A 1 171 ? 83.892 4.497 16.358 1.00 24.68 ? 361 ILE A CB 1 ATOM 1327 C CG1 . ILE A 1 171 ? 85.262 3.887 16.646 1.00 28.36 ? 361 ILE A CG1 1 ATOM 1328 C CG2 . ILE A 1 171 ? 83.241 3.791 15.181 1.00 24.69 ? 361 ILE A CG2 1 ATOM 1329 C CD1 . ILE A 1 171 ? 85.191 2.503 17.221 1.00 37.54 ? 361 ILE A CD1 1 ATOM 1330 N N . SER A 1 172 ? 86.238 6.459 15.133 1.00 21.60 ? 362 SER A N 1 ATOM 1331 C CA . SER A 1 172 ? 87.235 6.660 14.087 1.00 27.44 ? 362 SER A CA 1 ATOM 1332 C C . SER A 1 172 ? 87.863 5.357 13.601 1.00 33.17 ? 362 SER A C 1 ATOM 1333 O O . SER A 1 172 ? 87.961 4.384 14.348 1.00 37.55 ? 362 SER A O 1 ATOM 1334 C CB . SER A 1 172 ? 88.341 7.588 14.593 1.00 27.06 ? 362 SER A CB 1 ATOM 1335 O OG . SER A 1 172 ? 89.432 7.621 13.689 1.00 25.85 ? 362 SER A OG 1 ATOM 1336 N N . PRO A 1 173 ? 88.295 5.325 12.330 1.00 36.55 ? 363 PRO A N 1 ATOM 1337 C CA . PRO A 1 173 ? 88.922 4.138 11.739 1.00 36.34 ? 363 PRO A CA 1 ATOM 1338 C C . PRO A 1 173 ? 90.340 3.959 12.275 1.00 34.92 ? 363 PRO A C 1 ATOM 1339 O O . PRO A 1 173 ? 90.955 2.906 12.111 1.00 34.27 ? 363 PRO A O 1 ATOM 1340 C CB . PRO A 1 173 ? 88.903 4.451 10.248 1.00 38.96 ? 363 PRO A CB 1 ATOM 1341 C CG . PRO A 1 173 ? 89.100 5.939 10.232 1.00 41.73 ? 363 PRO A CG 1 ATOM 1342 C CD . PRO A 1 173 ? 88.160 6.399 11.328 1.00 37.39 ? 363 PRO A CD 1 ATOM 1343 N N . GLU A 1 174 ? 90.848 5.009 12.912 1.00 33.01 ? 364 GLU A N 1 ATOM 1344 C CA . GLU A 1 174 ? 92.181 5.003 13.498 1.00 32.29 ? 364 GLU A CA 1 ATOM 1345 C C . GLU A 1 174 ? 92.026 5.603 14.895 1.00 27.03 ? 364 GLU A C 1 ATOM 1346 O O . GLU A 1 174 ? 92.631 6.628 15.219 1.00 22.43 ? 364 GLU A O 1 ATOM 1347 C CB . GLU A 1 174 ? 93.130 5.852 12.647 1.00 38.22 ? 364 GLU A CB 1 ATOM 1348 C CG . GLU A 1 174 ? 94.602 5.702 13.006 1.00 51.79 ? 364 GLU A CG 1 ATOM 1349 C CD . GLU A 1 174 ? 95.515 6.532 12.113 1.00 58.53 ? 364 GLU A CD 1 ATOM 1350 O OE1 . GLU A 1 174 ? 95.478 6.345 10.876 1.00 57.65 ? 364 GLU A OE1 1 ATOM 1351 O OE2 . GLU A 1 174 ? 96.273 7.370 12.652 1.00 60.25 ? 364 GLU A OE2 1 ATOM 1352 N N . PRO A 1 175 ? 91.211 4.953 15.744 1.00 24.00 ? 365 PRO A N 1 ATOM 1353 C CA . PRO A 1 175 ? 90.910 5.357 17.124 1.00 20.27 ? 365 PRO A CA 1 ATOM 1354 C C . PRO A 1 175 ? 92.097 5.472 18.072 1.00 17.91 ? 365 PRO A C 1 ATOM 1355 O O . PRO A 1 175 ? 93.111 4.794 17.914 1.00 12.90 ? 365 PRO A O 1 ATOM 1356 C CB . PRO A 1 175 ? 89.925 4.286 17.582 1.00 17.59 ? 365 PRO A CB 1 ATOM 1357 C CG . PRO A 1 175 ? 90.430 3.069 16.873 1.00 16.97 ? 365 PRO A CG 1 ATOM 1358 C CD . PRO A 1 175 ? 90.673 3.605 15.477 1.00 19.63 ? 365 PRO A CD 1 ATOM 1359 N N . SER A 1 176 ? 91.950 6.338 19.067 1.00 18.61 ? 366 SER A N 1 ATOM 1360 C CA . SER A 1 176 ? 92.988 6.538 20.062 1.00 20.94 ? 366 SER A CA 1 ATOM 1361 C C . SER A 1 176 ? 92.416 6.135 21.418 1.00 24.25 ? 366 SER A C 1 ATOM 1362 O O . SER A 1 176 ? 91.255 5.742 21.521 1.00 24.52 ? 366 SER A O 1 ATOM 1363 C CB . SER A 1 176 ? 93.425 8.004 20.103 1.00 19.79 ? 366 SER A CB 1 ATOM 1364 O OG . SER A 1 176 ? 92.501 8.794 20.831 1.00 23.25 ? 366 SER A OG 1 ATOM 1365 N N . THR A 1 177 ? 93.238 6.243 22.453 1.00 24.39 ? 367 THR A N 1 ATOM 1366 C CA . THR A 1 177 ? 92.842 5.887 23.809 1.00 19.86 ? 367 THR A CA 1 ATOM 1367 C C . THR A 1 177 ? 92.647 7.143 24.657 1.00 19.91 ? 367 THR A C 1 ATOM 1368 O O . THR A 1 177 ? 92.419 7.053 25.866 1.00 12.70 ? 367 THR A O 1 ATOM 1369 C CB . THR A 1 177 ? 93.934 5.019 24.472 1.00 22.49 ? 367 THR A CB 1 ATOM 1370 O OG1 . THR A 1 177 ? 95.204 5.676 24.338 1.00 20.14 ? 367 THR A OG1 1 ATOM 1371 C CG2 . THR A 1 177 ? 94.013 3.644 23.816 1.00 13.40 ? 367 THR A CG2 1 ATOM 1372 N N . PHE A 1 178 ? 92.721 8.309 24.013 1.00 18.09 ? 368 PHE A N 1 ATOM 1373 C CA . PHE A 1 178 ? 92.600 9.591 24.711 1.00 17.77 ? 368 PHE A CA 1 ATOM 1374 C C . PHE A 1 178 ? 91.232 10.265 24.700 1.00 14.10 ? 368 PHE A C 1 ATOM 1375 O O . PHE A 1 178 ? 90.571 10.330 23.669 1.00 9.51 ? 368 PHE A O 1 ATOM 1376 C CB . PHE A 1 178 ? 93.610 10.588 24.139 1.00 20.28 ? 368 PHE A CB 1 ATOM 1377 C CG . PHE A 1 178 ? 95.013 10.065 24.074 1.00 22.64 ? 368 PHE A CG 1 ATOM 1378 C CD1 . PHE A 1 178 ? 95.718 10.090 22.874 1.00 19.68 ? 368 PHE A CD1 1 ATOM 1379 C CD2 . PHE A 1 178 ? 95.636 9.551 25.211 1.00 21.52 ? 368 PHE A CD2 1 ATOM 1380 C CE1 . PHE A 1 178 ? 97.028 9.609 22.803 1.00 25.41 ? 368 PHE A CE1 1 ATOM 1381 C CE2 . PHE A 1 178 ? 96.943 9.069 25.155 1.00 22.56 ? 368 PHE A CE2 1 ATOM 1382 C CZ . PHE A 1 178 ? 97.642 9.097 23.948 1.00 22.11 ? 368 PHE A CZ 1 ATOM 1383 N N . PHE A 1 179 ? 90.836 10.776 25.864 1.00 17.80 ? 369 PHE A N 1 ATOM 1384 C CA . PHE A 1 179 ? 89.583 11.512 26.045 1.00 16.42 ? 369 PHE A CA 1 ATOM 1385 C C . PHE A 1 179 ? 89.895 12.978 25.717 1.00 18.48 ? 369 PHE A C 1 ATOM 1386 O O . PHE A 1 179 ? 91.057 13.382 25.701 1.00 17.83 ? 369 PHE A O 1 ATOM 1387 C CB . PHE A 1 179 ? 89.126 11.436 27.509 1.00 14.95 ? 369 PHE A CB 1 ATOM 1388 C CG . PHE A 1 179 ? 88.111 10.365 27.787 1.00 12.02 ? 369 PHE A CG 1 ATOM 1389 C CD1 . PHE A 1 179 ? 86.808 10.480 27.311 1.00 12.10 ? 369 PHE A CD1 1 ATOM 1390 C CD2 . PHE A 1 179 ? 88.447 9.257 28.554 1.00 11.25 ? 369 PHE A CD2 1 ATOM 1391 C CE1 . PHE A 1 179 ? 85.852 9.507 27.599 1.00 17.91 ? 369 PHE A CE1 1 ATOM 1392 C CE2 . PHE A 1 179 ? 87.501 8.277 28.849 1.00 14.80 ? 369 PHE A CE2 1 ATOM 1393 C CZ . PHE A 1 179 ? 86.199 8.401 28.372 1.00 17.66 ? 369 PHE A CZ 1 ATOM 1394 N N . SER A 1 180 ? 88.869 13.777 25.459 1.00 24.54 ? 370 SER A N 1 ATOM 1395 C CA . SER A 1 180 ? 89.097 15.191 25.171 1.00 24.75 ? 370 SER A CA 1 ATOM 1396 C C . SER A 1 180 ? 89.057 15.946 26.499 1.00 27.07 ? 370 SER A C 1 ATOM 1397 O O . SER A 1 180 ? 88.449 15.481 27.468 1.00 27.16 ? 370 SER A O 1 ATOM 1398 C CB . SER A 1 180 ? 88.011 15.742 24.241 1.00 21.08 ? 370 SER A CB 1 ATOM 1399 O OG . SER A 1 180 ? 86.814 16.013 24.952 1.00 13.14 ? 370 SER A OG 1 ATOM 1400 N N . ASN A 1 181 ? 89.709 17.102 26.552 1.00 26.26 ? 371 ASN A N 1 ATOM 1401 C CA . ASN A 1 181 ? 89.705 17.890 27.774 1.00 23.04 ? 371 ASN A CA 1 ATOM 1402 C C . ASN A 1 181 ? 88.255 18.183 28.164 1.00 23.70 ? 371 ASN A C 1 ATOM 1403 O O . ASN A 1 181 ? 87.934 18.313 29.347 1.00 24.97 ? 371 ASN A O 1 ATOM 1404 C CB . ASN A 1 181 ? 90.505 19.183 27.575 1.00 26.09 ? 371 ASN A CB 1 ATOM 1405 C CG . ASN A 1 181 ? 90.022 20.002 26.395 1.00 30.13 ? 371 ASN A CG 1 ATOM 1406 O OD1 . ASN A 1 181 ? 89.667 19.458 25.341 1.00 29.89 ? 371 ASN A OD1 1 ATOM 1407 N ND2 . ASN A 1 181 ? 90.035 21.321 26.561 1.00 31.32 ? 371 ASN A ND2 1 ATOM 1408 N N . CYS A 1 182 ? 87.379 18.262 27.165 1.00 23.62 ? 372 CYS A N 1 ATOM 1409 C CA . CYS A 1 182 ? 85.959 18.508 27.403 1.00 25.76 ? 372 CYS A CA 1 ATOM 1410 C C . CYS A 1 182 ? 85.360 17.328 28.171 1.00 26.86 ? 372 CYS A C 1 ATOM 1411 O O . CYS A 1 182 ? 84.621 17.514 29.138 1.00 27.41 ? 372 CYS A O 1 ATOM 1412 C CB . CYS A 1 182 ? 85.208 18.692 26.074 1.00 26.30 ? 372 CYS A CB 1 ATOM 1413 S SG . CYS A 1 182 ? 85.659 20.189 25.132 1.00 30.79 ? 372 CYS A SG 1 ATOM 1414 N N . SER A 1 183 ? 85.684 16.113 27.738 1.00 23.49 ? 373 SER A N 1 ATOM 1415 C CA . SER A 1 183 ? 85.176 14.912 28.394 1.00 20.68 ? 373 SER A CA 1 ATOM 1416 C C . SER A 1 183 ? 85.611 14.866 29.853 1.00 19.13 ? 373 SER A C 1 ATOM 1417 O O . SER A 1 183 ? 84.883 14.379 30.711 1.00 18.59 ? 373 SER A O 1 ATOM 1418 C CB . SER A 1 183 ? 85.677 13.657 27.673 1.00 21.36 ? 373 SER A CB 1 ATOM 1419 O OG . SER A 1 183 ? 85.149 13.562 26.362 1.00 23.16 ? 373 SER A OG 1 ATOM 1420 N N . TYR A 1 184 ? 86.805 15.376 30.129 1.00 21.06 ? 374 TYR A N 1 ATOM 1421 C CA . TYR A 1 184 ? 87.331 15.389 31.486 1.00 23.26 ? 374 TYR A CA 1 ATOM 1422 C C . TYR A 1 184 ? 86.482 16.281 32.384 1.00 23.90 ? 374 TYR A C 1 ATOM 1423 O O . TYR A 1 184 ? 85.830 15.799 33.310 1.00 24.26 ? 374 TYR A O 1 ATOM 1424 C CB . TYR A 1 184 ? 88.776 15.890 31.485 1.00 26.31 ? 374 TYR A CB 1 ATOM 1425 C CG . TYR A 1 184 ? 89.421 15.926 32.852 1.00 30.18 ? 374 TYR A CG 1 ATOM 1426 C CD1 . TYR A 1 184 ? 90.055 14.801 33.378 1.00 34.50 ? 374 TYR A CD1 1 ATOM 1427 C CD2 . TYR A 1 184 ? 89.391 17.087 33.626 1.00 28.85 ? 374 TYR A CD2 1 ATOM 1428 C CE1 . TYR A 1 184 ? 90.645 14.832 34.643 1.00 30.50 ? 374 TYR A CE1 1 ATOM 1429 C CE2 . TYR A 1 184 ? 89.974 17.127 34.888 1.00 27.12 ? 374 TYR A CE2 1 ATOM 1430 C CZ . TYR A 1 184 ? 90.599 15.998 35.390 1.00 27.27 ? 374 TYR A CZ 1 ATOM 1431 O OH . TYR A 1 184 ? 91.173 16.038 36.638 1.00 27.54 ? 374 TYR A OH 1 ATOM 1432 N N . PHE A 1 185 ? 86.491 17.582 32.103 1.00 26.02 ? 375 PHE A N 1 ATOM 1433 C CA . PHE A 1 185 ? 85.730 18.550 32.892 1.00 27.53 ? 375 PHE A CA 1 ATOM 1434 C C . PHE A 1 185 ? 84.262 18.157 32.999 1.00 26.74 ? 375 PHE A C 1 ATOM 1435 O O . PHE A 1 185 ? 83.660 18.239 34.070 1.00 27.83 ? 375 PHE A O 1 ATOM 1436 C CB . PHE A 1 185 ? 85.844 19.945 32.268 1.00 25.60 ? 375 PHE A CB 1 ATOM 1437 C CG . PHE A 1 185 ? 87.253 20.463 32.195 1.00 26.39 ? 375 PHE A CG 1 ATOM 1438 C CD1 . PHE A 1 185 ? 87.784 20.904 30.985 1.00 27.65 ? 375 PHE A CD1 1 ATOM 1439 C CD2 . PHE A 1 185 ? 88.056 20.498 33.332 1.00 31.42 ? 375 PHE A CD2 1 ATOM 1440 C CE1 . PHE A 1 185 ? 89.093 21.371 30.906 1.00 27.13 ? 375 PHE A CE1 1 ATOM 1441 C CE2 . PHE A 1 185 ? 89.370 20.963 33.268 1.00 29.85 ? 375 PHE A CE2 1 ATOM 1442 C CZ . PHE A 1 185 ? 89.889 21.400 32.052 1.00 34.05 ? 375 PHE A CZ 1 ATOM 1443 N N . GLU A 1 186 ? 83.699 17.730 31.876 1.00 26.59 ? 376 GLU A N 1 ATOM 1444 C CA . GLU A 1 186 ? 82.304 17.319 31.811 1.00 26.66 ? 376 GLU A CA 1 ATOM 1445 C C . GLU A 1 186 ? 82.076 16.127 32.732 1.00 24.48 ? 376 GLU A C 1 ATOM 1446 O O . GLU A 1 186 ? 81.109 16.089 33.493 1.00 23.70 ? 376 GLU A O 1 ATOM 1447 C CB . GLU A 1 186 ? 81.954 16.958 30.366 1.00 29.33 ? 376 GLU A CB 1 ATOM 1448 C CG . GLU A 1 186 ? 80.499 16.641 30.116 1.00 35.33 ? 376 GLU A CG 1 ATOM 1449 C CD . GLU A 1 186 ? 80.162 16.643 28.636 1.00 42.86 ? 376 GLU A CD 1 ATOM 1450 O OE1 . GLU A 1 186 ? 79.008 16.321 28.289 1.00 50.78 ? 376 GLU A OE1 1 ATOM 1451 O OE2 . GLU A 1 186 ? 81.049 16.974 27.818 1.00 42.31 ? 376 GLU A OE2 1 ATOM 1452 N N . CYS A 1 187 ? 82.985 15.160 32.658 1.00 21.53 ? 377 CYS A N 1 ATOM 1453 C CA . CYS A 1 187 ? 82.919 13.962 33.483 1.00 20.79 ? 377 CYS A CA 1 ATOM 1454 C C . CYS A 1 187 ? 82.926 14.307 34.969 1.00 23.14 ? 377 CYS A C 1 ATOM 1455 O O . CYS A 1 187 ? 82.084 13.826 35.736 1.00 21.30 ? 377 CYS A O 1 ATOM 1456 C CB . CYS A 1 187 ? 84.106 13.053 33.175 1.00 24.57 ? 377 CYS A CB 1 ATOM 1457 S SG . CYS A 1 187 ? 84.258 11.637 34.272 1.00 20.19 ? 377 CYS A SG 1 ATOM 1458 N N . TRP A 1 188 ? 83.880 15.139 35.380 1.00 19.40 ? 378 TRP A N 1 ATOM 1459 C CA . TRP A 1 188 ? 83.964 15.521 36.779 1.00 22.88 ? 378 TRP A CA 1 ATOM 1460 C C . TRP A 1 188 ? 82.874 16.489 37.206 1.00 25.11 ? 378 TRP A C 1 ATOM 1461 O O . TRP A 1 188 ? 82.517 16.545 38.381 1.00 23.70 ? 378 TRP A O 1 ATOM 1462 C CB . TRP A 1 188 ? 85.349 16.080 37.098 1.00 22.77 ? 378 TRP A CB 1 ATOM 1463 C CG . TRP A 1 188 ? 86.342 14.978 37.219 1.00 24.52 ? 378 TRP A CG 1 ATOM 1464 C CD1 . TRP A 1 188 ? 87.275 14.602 36.293 1.00 27.62 ? 378 TRP A CD1 1 ATOM 1465 C CD2 . TRP A 1 188 ? 86.422 14.022 38.281 1.00 25.90 ? 378 TRP A CD2 1 ATOM 1466 N NE1 . TRP A 1 188 ? 87.926 13.467 36.712 1.00 25.79 ? 378 TRP A NE1 1 ATOM 1467 C CE2 . TRP A 1 188 ? 87.424 13.090 37.929 1.00 27.16 ? 378 TRP A CE2 1 ATOM 1468 C CE3 . TRP A 1 188 ? 85.743 13.862 39.497 1.00 24.58 ? 378 TRP A CE3 1 ATOM 1469 C CZ2 . TRP A 1 188 ? 87.762 12.006 38.750 1.00 26.36 ? 378 TRP A CZ2 1 ATOM 1470 C CZ3 . TRP A 1 188 ? 86.079 12.785 40.312 1.00 25.89 ? 378 TRP A CZ3 1 ATOM 1471 C CH2 . TRP A 1 188 ? 87.082 11.871 39.933 1.00 22.08 ? 378 TRP A CH2 1 ATOM 1472 N N . ASP A 1 189 ? 82.333 17.244 36.259 1.00 28.34 ? 379 ASP A N 1 ATOM 1473 C CA . ASP A 1 189 ? 81.259 18.160 36.598 1.00 32.50 ? 379 ASP A CA 1 ATOM 1474 C C . ASP A 1 189 ? 80.104 17.286 37.080 1.00 30.00 ? 379 ASP A C 1 ATOM 1475 O O . ASP A 1 189 ? 79.361 17.649 37.993 1.00 29.27 ? 379 ASP A O 1 ATOM 1476 C CB . ASP A 1 189 ? 80.819 18.963 35.375 1.00 37.94 ? 379 ASP A CB 1 ATOM 1477 C CG . ASP A 1 189 ? 79.831 20.060 35.728 1.00 44.27 ? 379 ASP A CG 1 ATOM 1478 O OD1 . ASP A 1 189 ? 80.243 21.038 36.388 1.00 51.40 ? 379 ASP A OD1 1 ATOM 1479 O OD2 . ASP A 1 189 ? 78.644 19.942 35.358 1.00 45.33 ? 379 ASP A OD2 1 ATOM 1480 N N . PHE A 1 190 ? 79.972 16.121 36.456 1.00 26.56 ? 380 PHE A N 1 ATOM 1481 C CA . PHE A 1 190 ? 78.923 15.174 36.806 1.00 28.07 ? 380 PHE A CA 1 ATOM 1482 C C . PHE A 1 190 ? 79.131 14.622 38.212 1.00 30.35 ? 380 PHE A C 1 ATOM 1483 O O . PHE A 1 190 ? 78.203 14.582 39.015 1.00 30.54 ? 380 PHE A O 1 ATOM 1484 C CB . PHE A 1 190 ? 78.909 14.015 35.809 1.00 25.30 ? 380 PHE A CB 1 ATOM 1485 C CG . PHE A 1 190 ? 77.905 12.950 36.136 1.00 22.82 ? 380 PHE A CG 1 ATOM 1486 C CD1 . PHE A 1 190 ? 76.540 13.223 36.083 1.00 24.04 ? 380 PHE A CD1 1 ATOM 1487 C CD2 . PHE A 1 190 ? 78.321 11.676 36.509 1.00 20.61 ? 380 PHE A CD2 1 ATOM 1488 C CE1 . PHE A 1 190 ? 75.601 12.241 36.398 1.00 23.73 ? 380 PHE A CE1 1 ATOM 1489 C CE2 . PHE A 1 190 ? 77.391 10.683 36.826 1.00 20.00 ? 380 PHE A CE2 1 ATOM 1490 C CZ . PHE A 1 190 ? 76.028 10.967 36.771 1.00 23.71 ? 380 PHE A CZ 1 ATOM 1491 N N . ILE A 1 191 ? 80.357 14.197 38.498 1.00 32.53 ? 381 ILE A N 1 ATOM 1492 C CA . ILE A 1 191 ? 80.696 13.632 39.797 1.00 32.15 ? 381 ILE A CA 1 ATOM 1493 C C . ILE A 1 191 ? 80.647 14.657 40.929 1.00 35.99 ? 381 ILE A C 1 ATOM 1494 O O . ILE A 1 191 ? 80.442 14.300 42.088 1.00 40.30 ? 381 ILE A O 1 ATOM 1495 C CB . ILE A 1 191 ? 82.091 12.974 39.745 1.00 30.16 ? 381 ILE A CB 1 ATOM 1496 C CG1 . ILE A 1 191 ? 82.078 11.848 38.705 1.00 28.91 ? 381 ILE A CG1 1 ATOM 1497 C CG2 . ILE A 1 191 ? 82.473 12.433 41.114 1.00 24.71 ? 381 ILE A CG2 1 ATOM 1498 C CD1 . ILE A 1 191 ? 83.402 11.129 38.534 1.00 26.20 ? 381 ILE A CD1 1 ATOM 1499 N N . MET A 1 192 ? 80.827 15.930 40.598 1.00 39.58 ? 382 MET A N 1 ATOM 1500 C CA . MET A 1 192 ? 80.784 16.980 41.608 1.00 38.69 ? 382 MET A CA 1 ATOM 1501 C C . MET A 1 192 ? 79.336 17.312 41.962 1.00 37.96 ? 382 MET A C 1 ATOM 1502 O O . MET A 1 192 ? 78.958 17.297 43.132 1.00 37.86 ? 382 MET A O 1 ATOM 1503 C CB . MET A 1 192 ? 81.488 18.241 41.101 1.00 44.26 ? 382 MET A CB 1 ATOM 1504 C CG . MET A 1 192 ? 82.957 18.054 40.755 1.00 51.78 ? 382 MET A CG 1 ATOM 1505 S SD . MET A 1 192 ? 83.935 17.436 42.133 1.00 61.55 ? 382 MET A SD 1 ATOM 1506 C CE . MET A 1 192 ? 84.138 18.944 43.102 1.00 62.16 ? 382 MET A CE 1 ATOM 1507 N N . ASN A 1 193 ? 78.533 17.608 40.944 1.00 37.85 ? 383 ASN A N 1 ATOM 1508 C CA . ASN A 1 193 ? 77.125 17.950 41.138 1.00 40.88 ? 383 ASN A CA 1 ATOM 1509 C C . ASN A 1 193 ? 76.354 16.717 41.593 1.00 40.17 ? 383 ASN A C 1 ATOM 1510 O O . ASN A 1 193 ? 75.969 16.622 42.756 1.00 39.90 ? 383 ASN A O 1 ATOM 1511 C CB . ASN A 1 193 ? 76.546 18.505 39.838 1.00 44.83 ? 383 ASN A CB 1 ATOM 1512 C CG . ASN A 1 193 ? 77.308 19.726 39.340 1.00 51.03 ? 383 ASN A CG 1 ATOM 1513 O OD1 . ASN A 1 193 ? 77.097 20.192 38.219 1.00 55.26 ? 383 ASN A OD1 1 ATOM 1514 N ND2 . ASN A 1 193 ? 78.199 20.252 40.177 1.00 48.73 ? 383 ASN A ND2 1 ATOM 1515 N N . HIS A 1 194 ? 76.112 15.781 40.681 1.00 42.10 ? 384 HIS A N 1 ATOM 1516 C CA . HIS A 1 194 ? 75.435 14.544 41.053 1.00 44.03 ? 384 HIS A CA 1 ATOM 1517 C C . HIS A 1 194 ? 76.524 13.770 41.790 1.00 46.02 ? 384 HIS A C 1 ATOM 1518 O O . HIS A 1 194 ? 77.709 13.979 41.525 1.00 49.35 ? 384 HIS A O 1 ATOM 1519 C CB . HIS A 1 194 ? 75.002 13.755 39.814 1.00 46.12 ? 384 HIS A CB 1 ATOM 1520 C CG . HIS A 1 194 ? 74.074 14.501 38.907 1.00 46.52 ? 384 HIS A CG 1 ATOM 1521 N ND1 . HIS A 1 194 ? 74.464 15.616 38.196 1.00 47.25 ? 384 HIS A ND1 1 ATOM 1522 C CD2 . HIS A 1 194 ? 72.779 14.280 38.580 1.00 47.14 ? 384 HIS A CD2 1 ATOM 1523 C CE1 . HIS A 1 194 ? 73.449 16.048 37.468 1.00 44.80 ? 384 HIS A CE1 1 ATOM 1524 N NE2 . HIS A 1 194 ? 72.415 15.255 37.683 1.00 48.54 ? 384 HIS A NE2 1 ATOM 1525 N N . ASN A 1 195 ? 76.156 12.886 42.707 1.00 44.17 ? 385 ASN A N 1 ATOM 1526 C CA . ASN A 1 195 ? 77.192 12.154 43.426 1.00 48.03 ? 385 ASN A CA 1 ATOM 1527 C C . ASN A 1 195 ? 77.166 10.640 43.288 1.00 45.02 ? 385 ASN A C 1 ATOM 1528 O O . ASN A 1 195 ? 76.572 9.946 44.111 1.00 44.68 ? 385 ASN A O 1 ATOM 1529 C CB . ASN A 1 195 ? 77.177 12.530 44.912 1.00 56.08 ? 385 ASN A CB 1 ATOM 1530 C CG . ASN A 1 195 ? 77.910 13.833 45.194 1.00 59.85 ? 385 ASN A CG 1 ATOM 1531 O OD1 . ASN A 1 195 ? 77.516 14.899 44.720 1.00 62.30 ? 385 ASN A OD1 1 ATOM 1532 N ND2 . ASN A 1 195 ? 78.989 13.749 45.968 1.00 57.68 ? 385 ASN A ND2 1 ATOM 1533 N N . PRO A 1 196 ? 77.820 10.109 42.239 1.00 41.97 ? 386 PRO A N 1 ATOM 1534 C CA . PRO A 1 196 ? 77.876 8.663 42.001 1.00 36.63 ? 386 PRO A CA 1 ATOM 1535 C C . PRO A 1 196 ? 78.631 8.014 43.160 1.00 36.37 ? 386 PRO A C 1 ATOM 1536 O O . PRO A 1 196 ? 79.816 7.702 43.047 1.00 43.24 ? 386 PRO A O 1 ATOM 1537 C CB . PRO A 1 196 ? 78.649 8.558 40.686 1.00 30.52 ? 386 PRO A CB 1 ATOM 1538 C CG . PRO A 1 196 ? 78.333 9.835 40.003 1.00 32.45 ? 386 PRO A CG 1 ATOM 1539 C CD . PRO A 1 196 ? 78.440 10.838 41.121 1.00 37.89 ? 386 PRO A CD 1 ATOM 1540 N N . GLU A 1 197 ? 77.940 7.824 44.275 1.00 33.97 ? 387 GLU A N 1 ATOM 1541 C CA . GLU A 1 197 ? 78.541 7.235 45.464 1.00 36.47 ? 387 GLU A CA 1 ATOM 1542 C C . GLU A 1 197 ? 79.055 5.814 45.244 1.00 32.55 ? 387 GLU A C 1 ATOM 1543 O O . GLU A 1 197 ? 80.083 5.426 45.806 1.00 28.28 ? 387 GLU A O 1 ATOM 1544 C CB . GLU A 1 197 ? 77.523 7.226 46.612 1.00 44.26 ? 387 GLU A CB 1 ATOM 1545 C CG . GLU A 1 197 ? 76.439 6.157 46.478 1.00 51.38 ? 387 GLU A CG 1 ATOM 1546 C CD . GLU A 1 197 ? 75.571 6.334 45.241 1.00 53.82 ? 387 GLU A CD 1 ATOM 1547 O OE1 . GLU A 1 197 ? 74.880 5.365 44.856 1.00 54.83 ? 387 GLU A OE1 1 ATOM 1548 O OE2 . GLU A 1 197 ? 75.566 7.440 44.659 1.00 51.44 ? 387 GLU A OE2 1 ATOM 1549 N N . CYS A 1 198 ? 78.346 5.047 44.421 1.00 26.30 ? 388 CYS A N 1 ATOM 1550 C CA . CYS A 1 198 ? 78.713 3.658 44.172 1.00 26.59 ? 388 CYS A CA 1 ATOM 1551 C C . CYS A 1 198 ? 80.089 3.424 43.547 1.00 26.67 ? 388 CYS A C 1 ATOM 1552 O O . CYS A 1 198 ? 80.585 2.298 43.565 1.00 21.72 ? 388 CYS A O 1 ATOM 1553 C CB . CYS A 1 198 ? 77.634 2.973 43.325 1.00 29.26 ? 388 CYS A CB 1 ATOM 1554 S SG . CYS A 1 198 ? 77.815 3.142 41.519 1.00 38.11 ? 388 CYS A SG 1 ATOM 1555 N N . ILE A 1 199 ? 80.712 4.466 43.002 1.00 25.73 ? 389 ILE A N 1 ATOM 1556 C CA . ILE A 1 199 ? 82.033 4.303 42.391 1.00 25.10 ? 389 ILE A CA 1 ATOM 1557 C C . ILE A 1 199 ? 83.183 4.806 43.265 1.00 28.40 ? 389 ILE A C 1 ATOM 1558 O O . ILE A 1 199 ? 84.308 4.960 42.785 1.00 31.40 ? 389 ILE A O 1 ATOM 1559 C CB . ILE A 1 199 ? 82.134 5.029 41.032 1.00 24.69 ? 389 ILE A CB 1 ATOM 1560 C CG1 . ILE A 1 199 ? 81.822 6.514 41.218 1.00 22.64 ? 389 ILE A CG1 1 ATOM 1561 C CG2 . ILE A 1 199 ? 81.214 4.368 40.017 1.00 19.48 ? 389 ILE A CG2 1 ATOM 1562 C CD1 . ILE A 1 199 ? 82.122 7.362 40.011 1.00 17.89 ? 389 ILE A CD1 1 ATOM 1563 N N . LEU A 1 200 ? 82.902 5.060 44.541 1.00 26.38 ? 390 LEU A N 1 ATOM 1564 C CA . LEU A 1 200 ? 83.915 5.543 45.478 1.00 19.33 ? 390 LEU A CA 1 ATOM 1565 C C . LEU A 1 200 ? 84.774 4.399 46.003 1.00 18.16 ? 390 LEU A C 1 ATOM 1566 O O . LEU A 1 200 ? 86.002 4.482 46.016 1.00 15.57 ? 390 LEU A O 1 ATOM 1567 C CB . LEU A 1 200 ? 83.246 6.229 46.664 1.00 19.87 ? 390 LEU A CB 1 ATOM 1568 C CG . LEU A 1 200 ? 82.335 7.405 46.344 1.00 19.71 ? 390 LEU A CG 1 ATOM 1569 C CD1 . LEU A 1 200 ? 81.443 7.695 47.540 1.00 17.79 ? 390 LEU A CD1 1 ATOM 1570 C CD2 . LEU A 1 200 ? 83.184 8.605 45.965 1.00 13.21 ? 390 LEU A CD2 1 ATOM 1571 N N . ASN A 1 201 ? 84.109 3.334 46.440 1.00 17.18 ? 391 ASN A N 1 ATOM 1572 C CA . ASN A 1 201 ? 84.779 2.161 46.984 1.00 19.77 ? 391 ASN A CA 1 ATOM 1573 C C . ASN A 1 201 ? 85.782 1.531 46.023 1.00 21.66 ? 391 ASN A C 1 ATOM 1574 O O . ASN A 1 201 ? 85.499 1.348 44.839 1.00 24.54 ? 391 ASN A O 1 ATOM 1575 C CB . ASN A 1 201 ? 83.738 1.116 47.364 1.00 17.41 ? 391 ASN A CB 1 ATOM 1576 C CG . ASN A 1 201 ? 82.935 0.653 46.173 1.00 20.05 ? 391 ASN A CG 1 ATOM 1577 O OD1 . ASN A 1 201 ? 83.110 -0.462 45.686 1.00 21.10 ? 391 ASN A OD1 1 ATOM 1578 N ND2 . ASN A 1 201 ? 82.057 1.518 45.684 1.00 28.21 ? 391 ASN A ND2 1 ATOM 1579 N N . GLU A 1 202 ? 86.957 1.202 46.547 1.00 22.83 ? 392 GLU A N 1 ATOM 1580 C CA . GLU A 1 202 ? 88.001 0.560 45.760 1.00 24.37 ? 392 GLU A CA 1 ATOM 1581 C C . GLU A 1 202 ? 87.697 -0.935 45.771 1.00 25.26 ? 392 GLU A C 1 ATOM 1582 O O . GLU A 1 202 ? 87.599 -1.546 46.834 1.00 28.79 ? 392 GLU A O 1 ATOM 1583 C CB . GLU A 1 202 ? 89.370 0.807 46.394 1.00 23.12 ? 392 GLU A CB 1 ATOM 1584 C CG . GLU A 1 202 ? 90.519 0.111 45.685 1.00 32.70 ? 392 GLU A CG 1 ATOM 1585 C CD . GLU A 1 202 ? 91.843 0.296 46.403 1.00 38.22 ? 392 GLU A CD 1 ATOM 1586 O OE1 . GLU A 1 202 ? 92.874 -0.191 45.890 1.00 39.64 ? 392 GLU A OE1 1 ATOM 1587 O OE2 . GLU A 1 202 ? 91.852 0.926 47.484 1.00 37.00 ? 392 GLU A OE2 1 ATOM 1588 N N . PRO A 1 203 ? 87.537 -1.545 44.590 1.00 23.93 ? 393 PRO A N 1 ATOM 1589 C CA . PRO A 1 203 ? 87.241 -2.978 44.567 1.00 23.17 ? 393 PRO A CA 1 ATOM 1590 C C . PRO A 1 203 ? 88.321 -3.828 45.240 1.00 24.44 ? 393 PRO A C 1 ATOM 1591 O O . PRO A 1 203 ? 89.501 -3.473 45.235 1.00 27.15 ? 393 PRO A O 1 ATOM 1592 C CB . PRO A 1 203 ? 87.101 -3.269 43.074 1.00 21.06 ? 393 PRO A CB 1 ATOM 1593 C CG . PRO A 1 203 ? 88.037 -2.279 42.451 1.00 14.23 ? 393 PRO A CG 1 ATOM 1594 C CD . PRO A 1 203 ? 87.733 -1.026 43.225 1.00 18.90 ? 393 PRO A CD 1 ATOM 1595 N N . LEU A 1 204 ? 87.905 -4.942 45.833 1.00 24.53 ? 394 LEU A N 1 ATOM 1596 C CA . LEU A 1 204 ? 88.835 -5.850 46.495 1.00 26.15 ? 394 LEU A CA 1 ATOM 1597 C C . LEU A 1 204 ? 89.336 -6.873 45.485 1.00 23.78 ? 394 LEU A C 1 ATOM 1598 O O . LEU A 1 204 ? 88.579 -7.321 44.620 1.00 17.43 ? 394 LEU A O 1 ATOM 1599 C CB . LEU A 1 204 ? 88.148 -6.569 47.660 1.00 31.49 ? 394 LEU A CB 1 ATOM 1600 C CG . LEU A 1 204 ? 87.712 -5.692 48.839 1.00 37.56 ? 394 LEU A CG 1 ATOM 1601 C CD1 . LEU A 1 204 ? 86.942 -6.525 49.857 1.00 33.16 ? 394 LEU A CD1 1 ATOM 1602 C CD2 . LEU A 1 204 ? 88.937 -5.056 49.474 1.00 34.62 ? 394 LEU A CD2 1 ATOM 1603 N N . GLY A 1 205 ? 90.611 -7.234 45.603 1.00 21.80 ? 395 GLY A N 1 ATOM 1604 C CA . GLY A 1 205 ? 91.216 -8.196 44.698 1.00 23.24 ? 395 GLY A CA 1 ATOM 1605 C C . GLY A 1 205 ? 90.320 -9.354 44.295 1.00 27.78 ? 395 GLY A C 1 ATOM 1606 O O . GLY A 1 205 ? 90.188 -9.659 43.107 1.00 26.16 ? 395 GLY A O 1 ATOM 1607 N N . THR A 1 206 ? 89.702 -9.997 45.281 1.00 26.36 ? 396 THR A N 1 ATOM 1608 C CA . THR A 1 206 ? 88.823 -11.134 45.027 1.00 27.96 ? 396 THR A CA 1 ATOM 1609 C C . THR A 1 206 ? 87.565 -10.789 44.227 1.00 28.66 ? 396 THR A C 1 ATOM 1610 O O . THR A 1 206 ? 86.960 -11.668 43.614 1.00 28.78 ? 396 THR A O 1 ATOM 1611 C CB . THR A 1 206 ? 88.391 -11.798 46.344 1.00 26.00 ? 396 THR A CB 1 ATOM 1612 O OG1 . THR A 1 206 ? 87.907 -10.793 47.241 1.00 27.47 ? 396 THR A OG1 1 ATOM 1613 C CG2 . THR A 1 206 ? 89.559 -12.529 46.982 1.00 32.10 ? 396 THR A CG2 1 ATOM 1614 N N . ASP A 1 207 ? 87.167 -9.519 44.240 1.00 29.55 ? 397 ASP A N 1 ATOM 1615 C CA . ASP A 1 207 ? 85.980 -9.086 43.504 1.00 28.89 ? 397 ASP A CA 1 ATOM 1616 C C . ASP A 1 207 ? 86.232 -9.031 42.001 1.00 24.62 ? 397 ASP A C 1 ATOM 1617 O O . ASP A 1 207 ? 85.296 -8.993 41.206 1.00 25.28 ? 397 ASP A O 1 ATOM 1618 C CB . ASP A 1 207 ? 85.524 -7.705 43.978 1.00 34.88 ? 397 ASP A CB 1 ATOM 1619 C CG . ASP A 1 207 ? 84.807 -7.752 45.310 1.00 44.00 ? 397 ASP A CG 1 ATOM 1620 O OD1 . ASP A 1 207 ? 83.835 -8.531 45.435 1.00 43.51 ? 397 ASP A OD1 1 ATOM 1621 O OD2 . ASP A 1 207 ? 85.209 -7.002 46.227 1.00 45.53 ? 397 ASP A OD2 1 ATOM 1622 N N . ILE A 1 208 ? 87.504 -9.029 41.624 1.00 20.12 ? 398 ILE A N 1 ATOM 1623 C CA . ILE A 1 208 ? 87.902 -8.965 40.226 1.00 16.25 ? 398 ILE A CA 1 ATOM 1624 C C . ILE A 1 208 ? 88.010 -10.369 39.624 1.00 17.44 ? 398 ILE A C 1 ATOM 1625 O O . ILE A 1 208 ? 88.844 -11.176 40.036 1.00 16.36 ? 398 ILE A O 1 ATOM 1626 C CB . ILE A 1 208 ? 89.244 -8.222 40.105 1.00 16.63 ? 398 ILE A CB 1 ATOM 1627 C CG1 . ILE A 1 208 ? 89.105 -6.838 40.739 1.00 5.38 ? 398 ILE A CG1 1 ATOM 1628 C CG2 . ILE A 1 208 ? 89.667 -8.114 38.649 1.00 18.28 ? 398 ILE A CG2 1 ATOM 1629 C CD1 . ILE A 1 208 ? 90.410 -6.082 40.849 1.00 19.87 ? 398 ILE A CD1 1 ATOM 1630 N N . ILE A 1 209 ? 87.157 -10.646 38.642 1.00 18.17 ? 399 ILE A N 1 ATOM 1631 C CA . ILE A 1 209 ? 87.115 -11.948 37.984 1.00 20.77 ? 399 ILE A CA 1 ATOM 1632 C C . ILE A 1 209 ? 88.183 -12.132 36.921 1.00 19.72 ? 399 ILE A C 1 ATOM 1633 O O . ILE A 1 209 ? 88.513 -13.257 36.548 1.00 20.38 ? 399 ILE A O 1 ATOM 1634 C CB . ILE A 1 209 ? 85.764 -12.173 37.307 1.00 23.07 ? 399 ILE A CB 1 ATOM 1635 C CG1 . ILE A 1 209 ? 85.555 -11.103 36.234 1.00 24.31 ? 399 ILE A CG1 1 ATOM 1636 C CG2 . ILE A 1 209 ? 84.650 -12.126 38.343 1.00 30.59 ? 399 ILE A CG2 1 ATOM 1637 C CD1 . ILE A 1 209 ? 84.395 -11.365 35.334 1.00 25.61 ? 399 ILE A CD1 1 ATOM 1638 N N . SER A 1 210 ? 88.705 -11.023 36.417 1.00 19.10 ? 400 SER A N 1 ATOM 1639 C CA . SER A 1 210 ? 89.725 -11.076 35.385 1.00 17.14 ? 400 SER A CA 1 ATOM 1640 C C . SER A 1 210 ? 91.078 -11.436 35.972 1.00 19.62 ? 400 SER A C 1 ATOM 1641 O O . SER A 1 210 ? 91.412 -11.030 37.085 1.00 21.59 ? 400 SER A O 1 ATOM 1642 C CB . SER A 1 210 ? 89.824 -9.724 34.686 1.00 16.24 ? 400 SER A CB 1 ATOM 1643 O OG . SER A 1 210 ? 90.181 -8.712 35.611 1.00 15.62 ? 400 SER A OG 1 ATOM 1644 N N . PRO A 1 211 ? 91.871 -12.223 35.233 1.00 21.10 ? 401 PRO A N 1 ATOM 1645 C CA . PRO A 1 211 ? 93.200 -12.623 35.699 1.00 19.66 ? 401 PRO A CA 1 ATOM 1646 C C . PRO A 1 211 ? 93.963 -11.381 36.133 1.00 17.63 ? 401 PRO A C 1 ATOM 1647 O O . PRO A 1 211 ? 93.948 -10.365 35.443 1.00 14.47 ? 401 PRO A O 1 ATOM 1648 C CB . PRO A 1 211 ? 93.807 -13.276 34.463 1.00 12.76 ? 401 PRO A CB 1 ATOM 1649 C CG . PRO A 1 211 ? 92.625 -13.945 33.852 1.00 15.74 ? 401 PRO A CG 1 ATOM 1650 C CD . PRO A 1 211 ? 91.546 -12.880 33.956 1.00 22.75 ? 401 PRO A CD 1 ATOM 1651 N N . PRO A 1 212 ? 94.630 -11.438 37.291 1.00 21.91 ? 402 PRO A N 1 ATOM 1652 C CA . PRO A 1 212 ? 95.366 -10.249 37.721 1.00 22.04 ? 402 PRO A CA 1 ATOM 1653 C C . PRO A 1 212 ? 96.411 -9.820 36.700 1.00 21.29 ? 402 PRO A C 1 ATOM 1654 O O . PRO A 1 212 ? 97.033 -10.654 36.043 1.00 22.41 ? 402 PRO A O 1 ATOM 1655 C CB . PRO A 1 212 ? 95.970 -10.680 39.057 1.00 20.62 ? 402 PRO A CB 1 ATOM 1656 C CG . PRO A 1 212 ? 96.110 -12.159 38.908 1.00 26.30 ? 402 PRO A CG 1 ATOM 1657 C CD . PRO A 1 212 ? 94.828 -12.552 38.233 1.00 17.52 ? 402 PRO A CD 1 ATOM 1658 N N . VAL A 1 213 ? 96.572 -8.509 36.554 1.00 17.28 ? 403 VAL A N 1 ATOM 1659 C CA . VAL A 1 213 ? 97.543 -7.947 35.628 1.00 13.12 ? 403 VAL A CA 1 ATOM 1660 C C . VAL A 1 213 ? 98.444 -7.008 36.404 1.00 15.54 ? 403 VAL A C 1 ATOM 1661 O O . VAL A 1 213 ? 97.966 -6.085 37.061 1.00 10.95 ? 403 VAL A O 1 ATOM 1662 C CB . VAL A 1 213 ? 96.863 -7.135 34.500 1.00 19.33 ? 403 VAL A CB 1 ATOM 1663 C CG1 . VAL A 1 213 ? 97.901 -6.264 33.783 1.00 9.51 ? 403 VAL A CG1 1 ATOM 1664 C CG2 . VAL A 1 213 ? 96.189 -8.077 33.509 1.00 6.87 ? 403 VAL A CG2 1 ATOM 1665 N N . CYS A 1 214 ? 99.749 -7.246 36.336 1.00 17.56 ? 404 CYS A N 1 ATOM 1666 C CA . CYS A 1 214 ? 100.682 -6.386 37.040 1.00 16.30 ? 404 CYS A CA 1 ATOM 1667 C C . CYS A 1 214 ? 101.008 -5.136 36.225 1.00 13.91 ? 404 CYS A C 1 ATOM 1668 O O . CYS A 1 214 ? 101.630 -5.217 35.165 1.00 5.67 ? 404 CYS A O 1 ATOM 1669 C CB . CYS A 1 214 ? 101.979 -7.129 37.374 1.00 18.19 ? 404 CYS A CB 1 ATOM 1670 S SG . CYS A 1 214 ? 103.188 -5.957 38.061 1.00 32.80 ? 404 CYS A SG 1 ATOM 1671 N N . GLY A 1 215 ? 100.584 -3.982 36.733 1.00 11.86 ? 405 GLY A N 1 ATOM 1672 C CA . GLY A 1 215 ? 100.839 -2.726 36.050 1.00 10.84 ? 405 GLY A CA 1 ATOM 1673 C C . GLY A 1 215 ? 99.576 -2.034 35.565 1.00 15.70 ? 405 GLY A C 1 ATOM 1674 O O . GLY A 1 215 ? 99.646 -1.018 34.868 1.00 13.55 ? 405 GLY A O 1 ATOM 1675 N N . ASN A 1 216 ? 98.417 -2.580 35.930 1.00 10.64 ? 406 ASN A N 1 ATOM 1676 C CA . ASN A 1 216 ? 97.146 -2.001 35.524 1.00 8.24 ? 406 ASN A CA 1 ATOM 1677 C C . ASN A 1 216 ? 96.645 -1.015 36.576 1.00 12.05 ? 406 ASN A C 1 ATOM 1678 O O . ASN A 1 216 ? 95.550 -0.467 36.461 1.00 7.92 ? 406 ASN A O 1 ATOM 1679 C CB . ASN A 1 216 ? 96.112 -3.105 35.303 1.00 15.55 ? 406 ASN A CB 1 ATOM 1680 C CG . ASN A 1 216 ? 95.745 -3.827 36.582 1.00 20.80 ? 406 ASN A CG 1 ATOM 1681 O OD1 . ASN A 1 216 ? 96.296 -3.549 37.649 1.00 23.29 ? 406 ASN A OD1 1 ATOM 1682 N ND2 . ASN A 1 216 ? 94.808 -4.764 36.480 1.00 19.82 ? 406 ASN A ND2 1 ATOM 1683 N N . GLU A 1 217 ? 97.462 -0.798 37.600 1.00 16.16 ? 407 GLU A N 1 ATOM 1684 C CA . GLU A 1 217 ? 97.139 0.121 38.687 1.00 17.15 ? 407 GLU A CA 1 ATOM 1685 C C . GLU A 1 217 ? 95.994 -0.367 39.561 1.00 16.86 ? 407 GLU A C 1 ATOM 1686 O O . GLU A 1 217 ? 95.387 0.406 40.299 1.00 15.13 ? 407 GLU A O 1 ATOM 1687 C CB . GLU A 1 217 ? 96.828 1.511 38.125 1.00 15.61 ? 407 GLU A CB 1 ATOM 1688 C CG . GLU A 1 217 ? 97.992 2.095 37.339 1.00 22.13 ? 407 GLU A CG 1 ATOM 1689 C CD . GLU A 1 217 ? 97.808 3.554 36.989 1.00 25.21 ? 407 GLU A CD 1 ATOM 1690 O OE1 . GLU A 1 217 ? 98.736 4.135 36.389 1.00 22.54 ? 407 GLU A OE1 1 ATOM 1691 O OE2 . GLU A 1 217 ? 96.741 4.120 37.312 1.00 30.69 ? 407 GLU A OE2 1 ATOM 1692 N N . LEU A 1 218 ? 95.705 -1.660 39.475 1.00 18.32 ? 408 LEU A N 1 ATOM 1693 C CA . LEU A 1 218 ? 94.652 -2.267 40.277 1.00 18.69 ? 408 LEU A CA 1 ATOM 1694 C C . LEU A 1 218 ? 95.276 -3.317 41.182 1.00 20.20 ? 408 LEU A C 1 ATOM 1695 O O . LEU A 1 218 ? 95.703 -4.372 40.712 1.00 22.17 ? 408 LEU A O 1 ATOM 1696 C CB . LEU A 1 218 ? 93.605 -2.922 39.379 1.00 14.00 ? 408 LEU A CB 1 ATOM 1697 C CG . LEU A 1 218 ? 92.713 -1.968 38.585 1.00 17.97 ? 408 LEU A CG 1 ATOM 1698 C CD1 . LEU A 1 218 ? 91.859 -2.769 37.614 1.00 5.39 ? 408 LEU A CD1 1 ATOM 1699 C CD2 . LEU A 1 218 ? 91.838 -1.155 39.546 1.00 8.45 ? 408 LEU A CD2 1 ATOM 1700 N N . LEU A 1 219 ? 95.346 -3.028 42.478 1.00 20.94 ? 409 LEU A N 1 ATOM 1701 C CA . LEU A 1 219 ? 95.927 -3.983 43.408 1.00 20.11 ? 409 LEU A CA 1 ATOM 1702 C C . LEU A 1 219 ? 95.070 -5.238 43.347 1.00 20.86 ? 409 LEU A C 1 ATOM 1703 O O . LEU A 1 219 ? 93.922 -5.252 43.797 1.00 20.37 ? 409 LEU A O 1 ATOM 1704 C CB . LEU A 1 219 ? 95.953 -3.418 44.829 1.00 11.84 ? 409 LEU A CB 1 ATOM 1705 C CG . LEU A 1 219 ? 96.710 -4.292 45.832 1.00 7.60 ? 409 LEU A CG 1 ATOM 1706 C CD1 . LEU A 1 219 ? 98.120 -4.548 45.332 1.00 8.64 ? 409 LEU A CD1 1 ATOM 1707 C CD2 . LEU A 1 219 ? 96.749 -3.609 47.184 1.00 7.01 ? 409 LEU A CD2 1 ATOM 1708 N N . GLU A 1 220 ? 95.633 -6.292 42.774 1.00 18.72 ? 410 GLU A N 1 ATOM 1709 C CA . GLU A 1 220 ? 94.903 -7.535 42.620 1.00 16.00 ? 410 GLU A CA 1 ATOM 1710 C C . GLU A 1 220 ? 95.534 -8.691 43.380 1.00 13.24 ? 410 GLU A C 1 ATOM 1711 O O . GLU A 1 220 ? 96.716 -8.659 43.722 1.00 9.66 ? 410 GLU A O 1 ATOM 1712 C CB . GLU A 1 220 ? 94.792 -7.860 41.130 1.00 21.21 ? 410 GLU A CB 1 ATOM 1713 C CG . GLU A 1 220 ? 94.126 -6.746 40.329 1.00 18.30 ? 410 GLU A CG 1 ATOM 1714 C CD . GLU A 1 220 ? 94.361 -6.865 38.838 1.00 22.05 ? 410 GLU A CD 1 ATOM 1715 O OE1 . GLU A 1 220 ? 95.537 -6.931 38.419 1.00 24.20 ? 410 GLU A OE1 1 ATOM 1716 O OE2 . GLU A 1 220 ? 93.369 -6.883 38.082 1.00 24.43 ? 410 GLU A OE2 1 ATOM 1717 N N . VAL A 1 221 ? 94.726 -9.712 43.645 1.00 13.35 ? 411 VAL A N 1 ATOM 1718 C CA . VAL A 1 221 ? 95.174 -10.890 44.373 1.00 11.41 ? 411 VAL A CA 1 ATOM 1719 C C . VAL A 1 221 ? 96.518 -11.421 43.886 1.00 11.37 ? 411 VAL A C 1 ATOM 1720 O O . VAL A 1 221 ? 96.734 -11.601 42.686 1.00 13.90 ? 411 VAL A O 1 ATOM 1721 C CB . VAL A 1 221 ? 94.109 -12.000 44.298 1.00 6.17 ? 411 VAL A CB 1 ATOM 1722 C CG1 . VAL A 1 221 ? 94.651 -13.298 44.870 1.00 8.00 ? 411 VAL A CG1 1 ATOM 1723 C CG2 . VAL A 1 221 ? 92.873 -11.561 45.077 1.00 1.00 ? 411 VAL A CG2 1 ATOM 1724 N N . GLY A 1 222 ? 97.419 -11.657 44.836 1.00 9.61 ? 412 GLY A N 1 ATOM 1725 C CA . GLY A 1 222 ? 98.739 -12.160 44.509 1.00 11.94 ? 412 GLY A CA 1 ATOM 1726 C C . GLY A 1 222 ? 99.773 -11.057 44.380 1.00 15.82 ? 412 GLY A C 1 ATOM 1727 O O . GLY A 1 222 ? 100.977 -11.319 44.401 1.00 22.84 ? 412 GLY A O 1 ATOM 1728 N N . GLU A 1 223 ? 99.309 -9.818 44.243 1.00 16.62 ? 413 GLU A N 1 ATOM 1729 C CA . GLU A 1 223 ? 100.213 -8.679 44.108 1.00 14.27 ? 413 GLU A CA 1 ATOM 1730 C C . GLU A 1 223 ? 100.387 -7.942 45.432 1.00 14.54 ? 413 GLU A C 1 ATOM 1731 O O . GLU A 1 223 ? 99.415 -7.713 46.157 1.00 11.31 ? 413 GLU A O 1 ATOM 1732 C CB . GLU A 1 223 ? 99.673 -7.686 43.080 1.00 13.90 ? 413 GLU A CB 1 ATOM 1733 C CG . GLU A 1 223 ? 99.127 -8.304 41.810 1.00 19.07 ? 413 GLU A CG 1 ATOM 1734 C CD . GLU A 1 223 ? 98.676 -7.250 40.810 1.00 21.62 ? 413 GLU A CD 1 ATOM 1735 O OE1 . GLU A 1 223 ? 97.936 -6.321 41.211 1.00 12.55 ? 413 GLU A OE1 1 ATOM 1736 O OE2 . GLU A 1 223 ? 99.061 -7.357 39.624 1.00 17.81 ? 413 GLU A OE2 1 ATOM 1737 N N . GLU A 1 224 ? 101.624 -7.571 45.743 1.00 12.23 ? 414 GLU A N 1 ATOM 1738 C CA . GLU A 1 224 ? 101.904 -6.824 46.964 1.00 18.28 ? 414 GLU A CA 1 ATOM 1739 C C . GLU A 1 224 ? 101.555 -5.368 46.692 1.00 19.91 ? 414 GLU A C 1 ATOM 1740 O O . GLU A 1 224 ? 101.068 -4.656 47.567 1.00 21.91 ? 414 GLU A O 1 ATOM 1741 C CB . GLU A 1 224 ? 103.384 -6.913 47.324 1.00 23.57 ? 414 GLU A CB 1 ATOM 1742 C CG . GLU A 1 224 ? 103.843 -8.268 47.802 1.00 28.57 ? 414 GLU A CG 1 ATOM 1743 C CD . GLU A 1 224 ? 105.348 -8.381 47.791 1.00 32.03 ? 414 GLU A CD 1 ATOM 1744 O OE1 . GLU A 1 224 ? 106.018 -7.367 48.082 1.00 29.93 ? 414 GLU A OE1 1 ATOM 1745 O OE2 . GLU A 1 224 ? 105.861 -9.482 47.498 1.00 36.66 ? 414 GLU A OE2 1 ATOM 1746 N N . CYS A 1 225 ? 101.806 -4.935 45.462 1.00 20.25 ? 415 CYS A N 1 ATOM 1747 C CA . CYS A 1 225 ? 101.528 -3.567 45.064 1.00 24.26 ? 415 CYS A CA 1 ATOM 1748 C C . CYS A 1 225 ? 101.413 -3.452 43.550 1.00 25.59 ? 415 CYS A C 1 ATOM 1749 O O . CYS A 1 225 ? 101.894 -4.312 42.816 1.00 28.59 ? 415 CYS A O 1 ATOM 1750 C CB . CYS A 1 225 ? 102.646 -2.661 45.555 1.00 27.14 ? 415 CYS A CB 1 ATOM 1751 S SG . CYS A 1 225 ? 104.288 -3.120 44.914 1.00 34.11 ? 415 CYS A SG 1 ATOM 1752 N N . ASP A 1 226 ? 100.778 -2.381 43.087 1.00 25.96 ? 416 ASP A N 1 ATOM 1753 C CA . ASP A 1 226 ? 100.622 -2.152 41.655 1.00 25.53 ? 416 ASP A CA 1 ATOM 1754 C C . ASP A 1 226 ? 100.575 -0.655 41.375 1.00 23.13 ? 416 ASP A C 1 ATOM 1755 O O . ASP A 1 226 ? 99.558 -0.006 41.609 1.00 19.72 ? 416 ASP A O 1 ATOM 1756 C CB . ASP A 1 226 ? 99.340 -2.812 41.143 1.00 26.90 ? 416 ASP A CB 1 ATOM 1757 C CG . ASP A 1 226 ? 99.301 -2.906 39.634 1.00 27.02 ? 416 ASP A CG 1 ATOM 1758 O OD1 . ASP A 1 226 ? 99.508 -1.870 38.968 1.00 26.46 ? 416 ASP A OD1 1 ATOM 1759 O OD2 . ASP A 1 226 ? 99.065 -4.016 39.114 1.00 31.26 ? 416 ASP A OD2 1 ATOM 1760 N N . CYS A 1 227 ? 101.680 -0.110 40.877 1.00 25.18 ? 417 CYS A N 1 ATOM 1761 C CA . CYS A 1 227 ? 101.753 1.317 40.579 1.00 29.29 ? 417 CYS A CA 1 ATOM 1762 C C . CYS A 1 227 ? 101.803 1.590 39.081 1.00 29.31 ? 417 CYS A C 1 ATOM 1763 O O . CYS A 1 227 ? 102.444 2.544 38.639 1.00 32.09 ? 417 CYS A O 1 ATOM 1764 C CB . CYS A 1 227 ? 102.977 1.943 41.267 1.00 31.65 ? 417 CYS A CB 1 ATOM 1765 S SG . CYS A 1 227 ? 104.601 1.226 40.832 1.00 38.90 ? 417 CYS A SG 1 ATOM 1766 N N . GLY A 1 228 ? 101.120 0.756 38.304 1.00 26.10 ? 418 GLY A N 1 ATOM 1767 C CA . GLY A 1 228 ? 101.109 0.935 36.864 1.00 25.65 ? 418 GLY A CA 1 ATOM 1768 C C . GLY A 1 228 ? 102.396 0.477 36.205 1.00 25.91 ? 418 GLY A C 1 ATOM 1769 O O . GLY A 1 228 ? 103.072 -0.426 36.698 1.00 30.42 ? 418 GLY A O 1 ATOM 1770 N N . THR A 1 229 ? 102.738 1.093 35.081 1.00 23.25 ? 419 THR A N 1 ATOM 1771 C CA . THR A 1 229 ? 103.953 0.726 34.369 1.00 26.18 ? 419 THR A CA 1 ATOM 1772 C C . THR A 1 229 ? 105.144 1.427 35.008 1.00 23.98 ? 419 THR A C 1 ATOM 1773 O O . THR A 1 229 ? 104.978 2.421 35.717 1.00 19.43 ? 419 THR A O 1 ATOM 1774 C CB . THR A 1 229 ? 103.875 1.128 32.882 1.00 27.79 ? 419 THR A CB 1 ATOM 1775 O OG1 . THR A 1 229 ? 103.828 2.558 32.770 1.00 34.82 ? 419 THR A OG1 1 ATOM 1776 C CG2 . THR A 1 229 ? 102.633 0.533 32.239 1.00 25.30 ? 419 THR A CG2 1 ATOM 1777 N N . PRO A 1 230 ? 106.361 0.909 34.776 1.00 23.55 ? 420 PRO A N 1 ATOM 1778 C CA . PRO A 1 230 ? 107.577 1.503 35.338 1.00 25.38 ? 420 PRO A CA 1 ATOM 1779 C C . PRO A 1 230 ? 107.660 2.993 35.025 1.00 30.62 ? 420 PRO A C 1 ATOM 1780 O O . PRO A 1 230 ? 108.130 3.789 35.842 1.00 33.90 ? 420 PRO A O 1 ATOM 1781 C CB . PRO A 1 230 ? 108.687 0.706 34.663 1.00 21.03 ? 420 PRO A CB 1 ATOM 1782 C CG . PRO A 1 230 ? 108.069 -0.653 34.523 1.00 27.42 ? 420 PRO A CG 1 ATOM 1783 C CD . PRO A 1 230 ? 106.680 -0.317 34.021 1.00 28.05 ? 420 PRO A CD 1 ATOM 1784 N N . GLU A 1 231 ? 107.187 3.364 33.841 1.00 33.66 ? 421 GLU A N 1 ATOM 1785 C CA . GLU A 1 231 ? 107.202 4.754 33.407 1.00 37.32 ? 421 GLU A CA 1 ATOM 1786 C C . GLU A 1 231 ? 106.243 5.626 34.217 1.00 35.78 ? 421 GLU A C 1 ATOM 1787 O O . GLU A 1 231 ? 106.592 6.737 34.613 1.00 38.09 ? 421 GLU A O 1 ATOM 1788 C CB . GLU A 1 231 ? 106.832 4.839 31.926 1.00 44.78 ? 421 GLU A CB 1 ATOM 1789 C CG . GLU A 1 231 ? 107.637 3.909 31.031 1.00 58.15 ? 421 GLU A CG 1 ATOM 1790 C CD . GLU A 1 231 ? 107.239 4.014 29.569 1.00 64.31 ? 421 GLU A CD 1 ATOM 1791 O OE1 . GLU A 1 231 ? 107.479 5.078 28.957 1.00 64.89 ? 421 GLU A OE1 1 ATOM 1792 O OE2 . GLU A 1 231 ? 106.679 3.032 29.036 1.00 67.46 ? 421 GLU A OE2 1 ATOM 1793 N N . ASN A 1 232 ? 105.040 5.116 34.464 1.00 29.29 ? 422 ASN A N 1 ATOM 1794 C CA . ASN A 1 232 ? 104.025 5.860 35.202 1.00 26.55 ? 422 ASN A CA 1 ATOM 1795 C C . ASN A 1 232 ? 104.088 5.729 36.717 1.00 28.69 ? 422 ASN A C 1 ATOM 1796 O O . ASN A 1 232 ? 103.470 6.520 37.435 1.00 28.25 ? 422 ASN A O 1 ATOM 1797 C CB . ASN A 1 232 ? 102.632 5.432 34.743 1.00 31.33 ? 422 ASN A CB 1 ATOM 1798 C CG . ASN A 1 232 ? 102.293 5.934 33.361 1.00 32.37 ? 422 ASN A CG 1 ATOM 1799 O OD1 . ASN A 1 232 ? 101.273 5.552 32.786 1.00 35.54 ? 422 ASN A OD1 1 ATOM 1800 N ND2 . ASN A 1 232 ? 103.140 6.802 32.821 1.00 32.13 ? 422 ASN A ND2 1 ATOM 1801 N N . CYS A 1 233 ? 104.825 4.737 37.203 1.00 29.67 ? 423 CYS A N 1 ATOM 1802 C CA . CYS A 1 233 ? 104.920 4.502 38.639 1.00 28.11 ? 423 CYS A CA 1 ATOM 1803 C C . CYS A 1 233 ? 105.422 5.692 39.436 1.00 29.56 ? 423 CYS A C 1 ATOM 1804 O O . CYS A 1 233 ? 106.468 6.261 39.141 1.00 27.47 ? 423 CYS A O 1 ATOM 1805 C CB . CYS A 1 233 ? 105.809 3.296 38.925 1.00 27.56 ? 423 CYS A CB 1 ATOM 1806 S SG . CYS A 1 233 ? 105.856 2.827 40.684 1.00 32.74 ? 423 CYS A SG 1 ATOM 1807 N N . GLN A 1 234 ? 104.657 6.057 40.458 1.00 34.21 ? 424 GLN A N 1 ATOM 1808 C CA . GLN A 1 234 ? 105.001 7.171 41.330 1.00 36.12 ? 424 GLN A CA 1 ATOM 1809 C C . GLN A 1 234 ? 105.084 6.655 42.761 1.00 34.59 ? 424 GLN A C 1 ATOM 1810 O O . GLN A 1 234 ? 105.103 7.434 43.711 1.00 39.15 ? 424 GLN A O 1 ATOM 1811 C CB . GLN A 1 234 ? 103.928 8.256 41.241 1.00 41.30 ? 424 GLN A CB 1 ATOM 1812 C CG . GLN A 1 234 ? 103.693 8.785 39.836 1.00 48.08 ? 424 GLN A CG 1 ATOM 1813 C CD . GLN A 1 234 ? 102.495 9.708 39.760 1.00 49.70 ? 424 GLN A CD 1 ATOM 1814 O OE1 . GLN A 1 234 ? 102.439 10.729 40.443 1.00 51.93 ? 424 GLN A OE1 1 ATOM 1815 N NE2 . GLN A 1 234 ? 101.525 9.350 38.928 1.00 55.76 ? 424 GLN A NE2 1 ATOM 1816 N N . ASN A 1 235 ? 105.128 5.334 42.903 1.00 31.00 ? 425 ASN A N 1 ATOM 1817 C CA . ASN A 1 235 ? 105.197 4.704 44.214 1.00 28.26 ? 425 ASN A CA 1 ATOM 1818 C C . ASN A 1 235 ? 106.618 4.256 44.550 1.00 28.61 ? 425 ASN A C 1 ATOM 1819 O O . ASN A 1 235 ? 107.136 3.300 43.972 1.00 25.23 ? 425 ASN A O 1 ATOM 1820 C CB . ASN A 1 235 ? 104.265 3.496 44.258 1.00 26.21 ? 425 ASN A CB 1 ATOM 1821 C CG . ASN A 1 235 ? 104.031 2.999 45.663 1.00 28.59 ? 425 ASN A CG 1 ATOM 1822 O OD1 . ASN A 1 235 ? 104.912 3.091 46.520 1.00 33.27 ? 425 ASN A OD1 1 ATOM 1823 N ND2 . ASN A 1 235 ? 102.844 2.456 45.910 1.00 27.23 ? 425 ASN A ND2 1 ATOM 1824 N N . GLU A 1 236 ? 107.241 4.949 45.496 1.00 30.57 ? 426 GLU A N 1 ATOM 1825 C CA . GLU A 1 236 ? 108.599 4.635 45.920 1.00 29.86 ? 426 GLU A CA 1 ATOM 1826 C C . GLU A 1 236 ? 108.668 3.255 46.572 1.00 29.35 ? 426 GLU A C 1 ATOM 1827 O O . GLU A 1 236 ? 109.734 2.639 46.649 1.00 24.65 ? 426 GLU A O 1 ATOM 1828 C CB . GLU A 1 236 ? 109.088 5.688 46.917 1.00 36.19 ? 426 GLU A CB 1 ATOM 1829 C CG . GLU A 1 236 ? 108.993 7.122 46.418 1.00 52.68 ? 426 GLU A CG 1 ATOM 1830 C CD . GLU A 1 236 ? 109.774 7.349 45.137 1.00 60.84 ? 426 GLU A CD 1 ATOM 1831 O OE1 . GLU A 1 236 ? 110.975 7.009 45.108 1.00 66.28 ? 426 GLU A OE1 1 ATOM 1832 O OE2 . GLU A 1 236 ? 109.189 7.870 44.163 1.00 64.30 ? 426 GLU A OE2 1 ATOM 1833 N N . CYS A 1 237 ? 107.521 2.770 47.033 1.00 29.25 ? 427 CYS A N 1 ATOM 1834 C CA . CYS A 1 237 ? 107.450 1.480 47.706 1.00 30.74 ? 427 CYS A CA 1 ATOM 1835 C C . CYS A 1 237 ? 107.313 0.293 46.768 1.00 31.77 ? 427 CYS A C 1 ATOM 1836 O O . CYS A 1 237 ? 107.638 -0.836 47.137 1.00 32.16 ? 427 CYS A O 1 ATOM 1837 C CB . CYS A 1 237 ? 106.263 1.464 48.664 1.00 27.50 ? 427 CYS A CB 1 ATOM 1838 S SG . CYS A 1 237 ? 105.997 3.029 49.544 1.00 28.90 ? 427 CYS A SG 1 ATOM 1839 N N . CYS A 1 238 ? 106.837 0.546 45.556 1.00 33.88 ? 428 CYS A N 1 ATOM 1840 C CA . CYS A 1 238 ? 106.611 -0.533 44.608 1.00 36.54 ? 428 CYS A CA 1 ATOM 1841 C C . CYS A 1 238 ? 107.616 -0.663 43.476 1.00 34.04 ? 428 CYS A C 1 ATOM 1842 O O . CYS A 1 238 ? 108.158 0.324 42.981 1.00 34.13 ? 428 CYS A O 1 ATOM 1843 C CB . CYS A 1 238 ? 105.206 -0.395 44.015 1.00 38.41 ? 428 CYS A CB 1 ATOM 1844 S SG . CYS A 1 238 ? 104.518 -1.918 43.292 1.00 40.30 ? 428 CYS A SG 1 ATOM 1845 N N . ASP A 1 239 ? 107.849 -1.907 43.076 1.00 33.51 ? 429 ASP A N 1 ATOM 1846 C CA . ASP A 1 239 ? 108.742 -2.218 41.974 1.00 31.09 ? 429 ASP A CA 1 ATOM 1847 C C . ASP A 1 239 ? 107.827 -2.505 40.786 1.00 29.70 ? 429 ASP A C 1 ATOM 1848 O O . ASP A 1 239 ? 107.564 -3.660 40.451 1.00 30.74 ? 429 ASP A O 1 ATOM 1849 C CB . ASP A 1 239 ? 109.578 -3.455 42.291 1.00 31.80 ? 429 ASP A CB 1 ATOM 1850 C CG . ASP A 1 239 ? 110.515 -3.816 41.166 1.00 30.22 ? 429 ASP A CG 1 ATOM 1851 O OD1 . ASP A 1 239 ? 111.433 -3.020 40.886 1.00 33.49 ? 429 ASP A OD1 1 ATOM 1852 O OD2 . ASP A 1 239 ? 110.328 -4.889 40.556 1.00 30.10 ? 429 ASP A OD2 1 ATOM 1853 N N . ALA A 1 240 ? 107.332 -1.434 40.177 1.00 25.89 ? 430 ALA A N 1 ATOM 1854 C CA . ALA A 1 240 ? 106.423 -1.501 39.039 1.00 24.79 ? 430 ALA A CA 1 ATOM 1855 C C . ALA A 1 240 ? 106.518 -2.766 38.190 1.00 25.02 ? 430 ALA A C 1 ATOM 1856 O O . ALA A 1 240 ? 105.528 -3.470 37.987 1.00 25.78 ? 430 ALA A O 1 ATOM 1857 C CB . ALA A 1 240 ? 106.630 -0.274 38.156 1.00 24.33 ? 430 ALA A CB 1 ATOM 1858 N N . ALA A 1 241 ? 107.715 -3.049 37.694 1.00 24.04 ? 431 ALA A N 1 ATOM 1859 C CA . ALA A 1 241 ? 107.939 -4.203 36.839 1.00 21.80 ? 431 ALA A CA 1 ATOM 1860 C C . ALA A 1 241 ? 107.475 -5.545 37.390 1.00 24.20 ? 431 ALA A C 1 ATOM 1861 O O . ALA A 1 241 ? 107.074 -6.418 36.625 1.00 28.93 ? 431 ALA A O 1 ATOM 1862 C CB . ALA A 1 241 ? 109.413 -4.284 36.473 1.00 22.67 ? 431 ALA A CB 1 ATOM 1863 N N . THR A 1 242 ? 107.511 -5.716 38.708 1.00 27.96 ? 432 THR A N 1 ATOM 1864 C CA . THR A 1 242 ? 107.131 -6.996 39.303 1.00 23.49 ? 432 THR A CA 1 ATOM 1865 C C . THR A 1 242 ? 105.952 -6.980 40.273 1.00 23.80 ? 432 THR A C 1 ATOM 1866 O O . THR A 1 242 ? 105.472 -8.039 40.674 1.00 24.38 ? 432 THR A O 1 ATOM 1867 C CB . THR A 1 242 ? 108.330 -7.623 40.044 1.00 24.10 ? 432 THR A CB 1 ATOM 1868 O OG1 . THR A 1 242 ? 108.616 -6.860 41.222 1.00 26.73 ? 432 THR A OG1 1 ATOM 1869 C CG2 . THR A 1 242 ? 109.565 -7.626 39.155 1.00 17.97 ? 432 THR A CG2 1 ATOM 1870 N N . CYS A 1 243 ? 105.487 -5.793 40.649 1.00 22.56 ? 433 CYS A N 1 ATOM 1871 C CA . CYS A 1 243 ? 104.381 -5.673 41.598 1.00 26.59 ? 433 CYS A CA 1 ATOM 1872 C C . CYS A 1 243 ? 104.770 -6.215 42.971 1.00 28.94 ? 433 CYS A C 1 ATOM 1873 O O . CYS A 1 243 ? 103.939 -6.731 43.718 1.00 31.16 ? 433 CYS A O 1 ATOM 1874 C CB . CYS A 1 243 ? 103.130 -6.387 41.065 1.00 21.34 ? 433 CYS A CB 1 ATOM 1875 S SG . CYS A 1 243 ? 102.313 -5.372 39.800 1.00 28.80 ? 433 CYS A SG 1 ATOM 1876 N N . LYS A 1 244 ? 106.054 -6.088 43.287 1.00 30.42 ? 434 LYS A N 1 ATOM 1877 C CA . LYS A 1 244 ? 106.599 -6.528 44.561 1.00 28.83 ? 434 LYS A CA 1 ATOM 1878 C C . LYS A 1 244 ? 107.079 -5.280 45.286 1.00 29.23 ? 434 LYS A C 1 ATOM 1879 O O . LYS A 1 244 ? 107.631 -4.377 44.660 1.00 32.58 ? 434 LYS A O 1 ATOM 1880 C CB . LYS A 1 244 ? 107.778 -7.475 44.333 1.00 28.44 ? 434 LYS A CB 1 ATOM 1881 C CG . LYS A 1 244 ? 107.406 -8.793 43.680 1.00 35.70 ? 434 LYS A CG 1 ATOM 1882 C CD . LYS A 1 244 ? 106.462 -9.594 44.566 1.00 41.63 ? 434 LYS A CD 1 ATOM 1883 C CE . LYS A 1 244 ? 106.066 -10.915 43.920 1.00 44.58 ? 434 LYS A CE 1 ATOM 1884 N NZ . LYS A 1 244 ? 105.154 -11.709 44.793 1.00 45.70 ? 434 LYS A NZ 1 ATOM 1885 N N . LEU A 1 245 ? 106.860 -5.216 46.596 1.00 27.20 ? 435 LEU A N 1 ATOM 1886 C CA . LEU A 1 245 ? 107.298 -4.057 47.366 1.00 21.03 ? 435 LEU A CA 1 ATOM 1887 C C . LEU A 1 245 ? 108.816 -4.059 47.444 1.00 20.57 ? 435 LEU A C 1 ATOM 1888 O O . LEU A 1 245 ? 109.444 -5.120 47.389 1.00 21.60 ? 435 LEU A O 1 ATOM 1889 C CB . LEU A 1 245 ? 106.715 -4.090 48.784 1.00 14.98 ? 435 LEU A CB 1 ATOM 1890 C CG . LEU A 1 245 ? 105.195 -3.960 48.945 1.00 17.43 ? 435 LEU A CG 1 ATOM 1891 C CD1 . LEU A 1 245 ? 104.830 -4.014 50.425 1.00 14.56 ? 435 LEU A CD1 1 ATOM 1892 C CD2 . LEU A 1 245 ? 104.721 -2.651 48.335 1.00 14.40 ? 435 LEU A CD2 1 ATOM 1893 N N . LYS A 1 246 ? 109.406 -2.872 47.555 1.00 19.76 ? 436 LYS A N 1 ATOM 1894 C CA . LYS A 1 246 ? 110.854 -2.758 47.662 1.00 20.97 ? 436 LYS A CA 1 ATOM 1895 C C . LYS A 1 246 ? 111.254 -3.462 48.949 1.00 23.57 ? 436 LYS A C 1 ATOM 1896 O O . LYS A 1 246 ? 110.477 -3.499 49.903 1.00 22.00 ? 436 LYS A O 1 ATOM 1897 C CB . LYS A 1 246 ? 111.278 -1.294 47.764 1.00 19.40 ? 436 LYS A CB 1 ATOM 1898 C CG . LYS A 1 246 ? 110.903 -0.426 46.589 1.00 18.00 ? 436 LYS A CG 1 ATOM 1899 C CD . LYS A 1 246 ? 111.708 -0.765 45.358 1.00 17.87 ? 436 LYS A CD 1 ATOM 1900 C CE . LYS A 1 246 ? 111.487 0.287 44.275 1.00 28.40 ? 436 LYS A CE 1 ATOM 1901 N NZ . LYS A 1 246 ? 111.778 1.668 44.771 1.00 18.30 ? 436 LYS A NZ 1 ATOM 1902 N N . SER A 1 247 ? 112.458 -4.022 48.982 1.00 25.21 ? 437 SER A N 1 ATOM 1903 C CA . SER A 1 247 ? 112.925 -4.692 50.187 1.00 27.72 ? 437 SER A CA 1 ATOM 1904 C C . SER A 1 247 ? 112.917 -3.664 51.316 1.00 29.07 ? 437 SER A C 1 ATOM 1905 O O . SER A 1 247 ? 113.354 -2.525 51.133 1.00 27.36 ? 437 SER A O 1 ATOM 1906 C CB . SER A 1 247 ? 114.347 -5.232 49.988 1.00 31.30 ? 437 SER A CB 1 ATOM 1907 O OG . SER A 1 247 ? 114.389 -6.230 48.981 1.00 36.03 ? 437 SER A OG 1 ATOM 1908 N N . GLY A 1 248 ? 112.398 -4.059 52.472 1.00 29.29 ? 438 GLY A N 1 ATOM 1909 C CA . GLY A 1 248 ? 112.356 -3.148 53.600 1.00 27.95 ? 438 GLY A CA 1 ATOM 1910 C C . GLY A 1 248 ? 111.018 -2.464 53.794 1.00 25.54 ? 438 GLY A C 1 ATOM 1911 O O . GLY A 1 248 ? 110.725 -1.964 54.881 1.00 24.17 ? 438 GLY A O 1 ATOM 1912 N N . SER A 1 249 ? 110.202 -2.433 52.747 1.00 25.21 ? 439 SER A N 1 ATOM 1913 C CA . SER A 1 249 ? 108.890 -1.801 52.835 1.00 25.91 ? 439 SER A CA 1 ATOM 1914 C C . SER A 1 249 ? 107.904 -2.705 53.563 1.00 22.36 ? 439 SER A C 1 ATOM 1915 O O . SER A 1 249 ? 107.948 -3.925 53.424 1.00 22.67 ? 439 SER A O 1 ATOM 1916 C CB . SER A 1 249 ? 108.358 -1.484 51.438 1.00 26.08 ? 439 SER A CB 1 ATOM 1917 O OG . SER A 1 249 ? 109.217 -0.581 50.763 1.00 39.96 ? 439 SER A OG 1 ATOM 1918 N N . GLN A 1 250 ? 107.021 -2.104 54.350 1.00 19.43 ? 440 GLN A N 1 ATOM 1919 C CA . GLN A 1 250 ? 106.026 -2.877 55.079 1.00 21.24 ? 440 GLN A CA 1 ATOM 1920 C C . GLN A 1 250 ? 104.726 -2.872 54.287 1.00 20.47 ? 440 GLN A C 1 ATOM 1921 O O . GLN A 1 250 ? 103.992 -3.860 54.262 1.00 19.15 ? 440 GLN A O 1 ATOM 1922 C CB . GLN A 1 250 ? 105.783 -2.272 56.466 1.00 21.36 ? 440 GLN A CB 1 ATOM 1923 C CG . GLN A 1 250 ? 106.987 -2.302 57.396 1.00 15.98 ? 440 GLN A CG 1 ATOM 1924 C CD . GLN A 1 250 ? 106.687 -1.671 58.741 1.00 18.08 ? 440 GLN A CD 1 ATOM 1925 O OE1 . GLN A 1 250 ? 106.352 -0.490 58.823 1.00 17.54 ? 440 GLN A OE1 1 ATOM 1926 N NE2 . GLN A 1 250 ? 106.800 -2.457 59.805 1.00 16.43 ? 440 GLN A NE2 1 ATOM 1927 N N . CYS A 1 251 ? 104.461 -1.749 53.632 1.00 18.72 ? 441 CYS A N 1 ATOM 1928 C CA . CYS A 1 251 ? 103.256 -1.572 52.837 1.00 20.99 ? 441 CYS A CA 1 ATOM 1929 C C . CYS A 1 251 ? 103.564 -0.720 51.608 1.00 24.26 ? 441 CYS A C 1 ATOM 1930 O O . CYS A 1 251 ? 104.671 -0.195 51.463 1.00 24.92 ? 441 CYS A O 1 ATOM 1931 C CB . CYS A 1 251 ? 102.180 -0.885 53.680 1.00 21.71 ? 441 CYS A CB 1 ATOM 1932 S SG . CYS A 1 251 ? 102.743 0.683 54.422 1.00 28.16 ? 441 CYS A SG 1 ATOM 1933 N N . GLY A 1 252 ? 102.575 -0.584 50.730 1.00 24.15 ? 442 GLY A N 1 ATOM 1934 C CA . GLY A 1 252 ? 102.755 0.211 49.530 1.00 21.72 ? 442 GLY A CA 1 ATOM 1935 C C . GLY A 1 252 ? 101.476 0.926 49.151 1.00 19.81 ? 442 GLY A C 1 ATOM 1936 O O . GLY A 1 252 ? 101.392 1.562 48.103 1.00 17.71 ? 442 GLY A O 1 ATOM 1937 N N . HIS A 1 253 ? 100.473 0.819 50.015 1.00 22.94 ? 443 HIS A N 1 ATOM 1938 C CA . HIS A 1 253 ? 99.181 1.451 49.778 1.00 27.24 ? 443 HIS A CA 1 ATOM 1939 C C . HIS A 1 253 ? 98.349 1.366 51.054 1.00 25.21 ? 443 HIS A C 1 ATOM 1940 O O . HIS A 1 253 ? 98.664 0.586 51.954 1.00 26.86 ? 443 HIS A O 1 ATOM 1941 C CB . HIS A 1 253 ? 98.438 0.728 48.656 1.00 34.20 ? 443 HIS A CB 1 ATOM 1942 C CG . HIS A 1 253 ? 97.662 -0.459 49.127 1.00 38.58 ? 443 HIS A CG 1 ATOM 1943 N ND1 . HIS A 1 253 ? 98.253 -1.522 49.776 1.00 43.19 ? 443 HIS A ND1 1 ATOM 1944 C CD2 . HIS A 1 253 ? 96.336 -0.728 49.094 1.00 43.89 ? 443 HIS A CD2 1 ATOM 1945 C CE1 . HIS A 1 253 ? 97.324 -2.393 50.126 1.00 49.32 ? 443 HIS A CE1 1 ATOM 1946 N NE2 . HIS A 1 253 ? 96.151 -1.935 49.725 1.00 50.98 ? 443 HIS A NE2 1 ATOM 1947 N N . GLY A 1 254 ? 97.283 2.158 51.124 1.00 21.45 ? 444 GLY A N 1 ATOM 1948 C CA . GLY A 1 254 ? 96.428 2.133 52.298 1.00 18.07 ? 444 GLY A CA 1 ATOM 1949 C C . GLY A 1 254 ? 96.470 3.409 53.114 1.00 17.31 ? 444 GLY A C 1 ATOM 1950 O O . GLY A 1 254 ? 97.505 4.063 53.216 1.00 18.58 ? 444 GLY A O 1 ATOM 1951 N N . ASP A 1 255 ? 95.336 3.760 53.705 1.00 17.45 ? 445 ASP A N 1 ATOM 1952 C CA . ASP A 1 255 ? 95.235 4.963 54.516 1.00 21.87 ? 445 ASP A CA 1 ATOM 1953 C C . ASP A 1 255 ? 96.200 4.935 55.689 1.00 23.69 ? 445 ASP A C 1 ATOM 1954 O O . ASP A 1 255 ? 96.495 5.972 56.285 1.00 26.22 ? 445 ASP A O 1 ATOM 1955 C CB . ASP A 1 255 ? 93.804 5.120 55.023 1.00 24.68 ? 445 ASP A CB 1 ATOM 1956 C CG . ASP A 1 255 ? 92.823 5.418 53.905 1.00 28.76 ? 445 ASP A CG 1 ATOM 1957 O OD1 . ASP A 1 255 ? 91.618 5.142 54.080 1.00 30.87 ? 445 ASP A OD1 1 ATOM 1958 O OD2 . ASP A 1 255 ? 93.259 5.939 52.856 1.00 32.29 ? 445 ASP A OD2 1 ATOM 1959 N N . CYS A 1 256 ? 96.688 3.744 56.020 1.00 22.81 ? 446 CYS A N 1 ATOM 1960 C CA . CYS A 1 256 ? 97.622 3.594 57.126 1.00 25.76 ? 446 CYS A CA 1 ATOM 1961 C C . CYS A 1 256 ? 99.021 3.225 56.655 1.00 29.78 ? 446 CYS A C 1 ATOM 1962 O O . CYS A 1 256 ? 99.753 2.516 57.347 1.00 29.87 ? 446 CYS A O 1 ATOM 1963 C CB . CYS A 1 256 ? 97.117 2.545 58.116 1.00 24.30 ? 446 CYS A CB 1 ATOM 1964 S SG . CYS A 1 256 ? 95.658 3.076 59.064 1.00 23.62 ? 446 CYS A SG 1 ATOM 1965 N N . CYS A 1 257 ? 99.384 3.705 55.470 1.00 30.97 ? 447 CYS A N 1 ATOM 1966 C CA . CYS A 1 257 ? 100.705 3.451 54.918 1.00 29.99 ? 447 CYS A CA 1 ATOM 1967 C C . CYS A 1 257 ? 101.386 4.789 54.662 1.00 29.51 ? 447 CYS A C 1 ATOM 1968 O O . CYS A 1 257 ? 100.994 5.534 53.768 1.00 29.67 ? 447 CYS A O 1 ATOM 1969 C CB . CYS A 1 257 ? 100.612 2.661 53.613 1.00 28.47 ? 447 CYS A CB 1 ATOM 1970 S SG . CYS A 1 257 ? 102.247 2.098 53.046 1.00 27.50 ? 447 CYS A SG 1 ATOM 1971 N N . GLU A 1 258 ? 102.400 5.095 55.461 1.00 30.32 ? 448 GLU A N 1 ATOM 1972 C CA . GLU A 1 258 ? 103.120 6.351 55.324 1.00 32.03 ? 448 GLU A CA 1 ATOM 1973 C C . GLU A 1 258 ? 104.562 6.106 54.913 1.00 33.99 ? 448 GLU A C 1 ATOM 1974 O O . GLU A 1 258 ? 105.341 5.492 55.647 1.00 28.94 ? 448 GLU A O 1 ATOM 1975 C CB . GLU A 1 258 ? 103.059 7.125 56.641 1.00 35.36 ? 448 GLU A CB 1 ATOM 1976 C CG . GLU A 1 258 ? 101.644 7.537 57.020 1.00 47.81 ? 448 GLU A CG 1 ATOM 1977 C CD . GLU A 1 258 ? 101.492 7.896 58.489 1.00 56.09 ? 448 GLU A CD 1 ATOM 1978 O OE1 . GLU A 1 258 ? 100.371 8.281 58.886 1.00 57.77 ? 448 GLU A OE1 1 ATOM 1979 O OE2 . GLU A 1 258 ? 102.482 7.789 59.246 1.00 58.75 ? 448 GLU A OE2 1 ATOM 1980 N N . GLN A 1 259 ? 104.904 6.589 53.724 1.00 33.81 ? 449 GLN A N 1 ATOM 1981 C CA . GLN A 1 259 ? 106.243 6.430 53.187 1.00 33.10 ? 449 GLN A CA 1 ATOM 1982 C C . GLN A 1 259 ? 106.711 4.985 53.287 1.00 31.12 ? 449 GLN A C 1 ATOM 1983 O O . GLN A 1 259 ? 107.749 4.694 53.878 1.00 32.35 ? 449 GLN A O 1 ATOM 1984 C CB . GLN A 1 259 ? 107.212 7.361 53.916 1.00 37.51 ? 449 GLN A CB 1 ATOM 1985 C CG . GLN A 1 259 ? 106.956 8.836 53.630 1.00 43.69 ? 449 GLN A CG 1 ATOM 1986 C CD . GLN A 1 259 ? 107.857 9.756 54.430 1.00 52.27 ? 449 GLN A CD 1 ATOM 1987 O OE1 . GLN A 1 259 ? 109.085 9.657 54.364 1.00 57.05 ? 449 GLN A OE1 1 ATOM 1988 N NE2 . GLN A 1 259 ? 107.250 10.661 55.191 1.00 56.94 ? 449 GLN A NE2 1 ATOM 1989 N N . CYS A 1 260 ? 105.916 4.085 52.715 1.00 28.23 ? 450 CYS A N 1 ATOM 1990 C CA . CYS A 1 260 ? 106.229 2.661 52.687 1.00 22.20 ? 450 CYS A CA 1 ATOM 1991 C C . CYS A 1 260 ? 106.199 1.951 54.033 1.00 18.73 ? 450 CYS A C 1 ATOM 1992 O O . CYS A 1 260 ? 106.619 0.797 54.134 1.00 15.98 ? 450 CYS A O 1 ATOM 1993 C CB . CYS A 1 260 ? 107.595 2.457 52.043 1.00 19.30 ? 450 CYS A CB 1 ATOM 1994 S SG . CYS A 1 260 ? 107.774 3.354 50.472 1.00 21.47 ? 450 CYS A SG 1 ATOM 1995 N N . LYS A 1 261 ? 105.699 2.627 55.063 1.00 18.72 ? 451 LYS A N 1 ATOM 1996 C CA . LYS A 1 261 ? 105.641 2.026 56.391 1.00 17.18 ? 451 LYS A CA 1 ATOM 1997 C C . LYS A 1 261 ? 104.259 2.117 57.013 1.00 13.56 ? 451 LYS A C 1 ATOM 1998 O O . LYS A 1 261 ? 103.406 2.876 56.558 1.00 16.61 ? 451 LYS A O 1 ATOM 1999 C CB . LYS A 1 261 ? 106.653 2.701 57.324 1.00 18.62 ? 451 LYS A CB 1 ATOM 2000 C CG . LYS A 1 261 ? 108.081 2.714 56.794 1.00 23.44 ? 451 LYS A CG 1 ATOM 2001 C CD . LYS A 1 261 ? 108.566 1.303 56.484 1.00 28.26 ? 451 LYS A CD 1 ATOM 2002 C CE . LYS A 1 261 ? 109.969 1.310 55.901 1.00 24.42 ? 451 LYS A CE 1 ATOM 2003 N NZ . LYS A 1 261 ? 110.946 1.880 56.861 1.00 34.64 ? 451 LYS A NZ 1 ATOM 2004 N N . PHE A 1 262 ? 104.048 1.327 58.059 1.00 13.14 ? 452 PHE A N 1 ATOM 2005 C CA . PHE A 1 262 ? 102.785 1.321 58.782 1.00 7.63 ? 452 PHE A CA 1 ATOM 2006 C C . PHE A 1 262 ? 102.719 2.590 59.612 1.00 8.58 ? 452 PHE A C 1 ATOM 2007 O O . PHE A 1 262 ? 103.683 2.939 60.291 1.00 11.77 ? 452 PHE A O 1 ATOM 2008 C CB . PHE A 1 262 ? 102.713 0.115 59.720 1.00 6.78 ? 452 PHE A CB 1 ATOM 2009 C CG . PHE A 1 262 ? 102.607 -1.204 59.013 1.00 10.61 ? 452 PHE A CG 1 ATOM 2010 C CD1 . PHE A 1 262 ? 103.117 -2.360 59.599 1.00 12.74 ? 452 PHE A CD1 1 ATOM 2011 C CD2 . PHE A 1 262 ? 101.975 -1.302 57.775 1.00 11.48 ? 452 PHE A CD2 1 ATOM 2012 C CE1 . PHE A 1 262 ? 103.000 -3.599 58.964 1.00 12.67 ? 452 PHE A CE1 1 ATOM 2013 C CE2 . PHE A 1 262 ? 101.850 -2.533 57.132 1.00 12.56 ? 452 PHE A CE2 1 ATOM 2014 C CZ . PHE A 1 262 ? 102.365 -3.686 57.729 1.00 13.23 ? 452 PHE A CZ 1 ATOM 2015 N N . SER A 1 263 ? 101.592 3.288 59.557 1.00 9.94 ? 453 SER A N 1 ATOM 2016 C CA . SER A 1 263 ? 101.441 4.503 60.340 1.00 15.25 ? 453 SER A CA 1 ATOM 2017 C C . SER A 1 263 ? 101.545 4.148 61.822 1.00 16.57 ? 453 SER A C 1 ATOM 2018 O O . SER A 1 263 ? 101.271 3.014 62.220 1.00 16.55 ? 453 SER A O 1 ATOM 2019 C CB . SER A 1 263 ? 100.090 5.147 60.048 1.00 15.87 ? 453 SER A CB 1 ATOM 2020 O OG . SER A 1 263 ? 99.984 5.466 58.673 1.00 25.16 ? 453 SER A OG 1 ATOM 2021 N N . LYS A 1 264 ? 101.948 5.114 62.638 1.00 18.96 ? 454 LYS A N 1 ATOM 2022 C CA . LYS A 1 264 ? 102.085 4.874 64.066 1.00 23.43 ? 454 LYS A CA 1 ATOM 2023 C C . LYS A 1 264 ? 100.740 4.521 64.687 1.00 24.74 ? 454 LYS A C 1 ATOM 2024 O O . LYS A 1 264 ? 99.727 5.166 64.409 1.00 22.62 ? 454 LYS A O 1 ATOM 2025 C CB . LYS A 1 264 ? 102.671 6.108 64.756 1.00 28.35 ? 454 LYS A CB 1 ATOM 2026 C CG . LYS A 1 264 ? 104.077 6.450 64.291 1.00 44.84 ? 454 LYS A CG 1 ATOM 2027 C CD . LYS A 1 264 ? 104.653 7.653 65.025 1.00 49.61 ? 454 LYS A CD 1 ATOM 2028 C CE . LYS A 1 264 ? 106.096 7.904 64.596 1.00 50.40 ? 454 LYS A CE 1 ATOM 2029 N NZ . LYS A 1 264 ? 106.722 9.040 65.328 1.00 52.66 ? 454 LYS A NZ 1 ATOM 2030 N N . SER A 1 265 ? 100.740 3.484 65.520 1.00 24.07 ? 455 SER A N 1 ATOM 2031 C CA . SER A 1 265 ? 99.532 3.037 66.203 1.00 20.77 ? 455 SER A CA 1 ATOM 2032 C C . SER A 1 265 ? 98.805 4.240 66.786 1.00 21.47 ? 455 SER A C 1 ATOM 2033 O O . SER A 1 265 ? 99.407 5.057 67.482 1.00 23.18 ? 455 SER A O 1 ATOM 2034 C CB . SER A 1 265 ? 99.894 2.069 67.329 1.00 20.71 ? 455 SER A CB 1 ATOM 2035 O OG . SER A 1 265 ? 98.761 1.735 68.110 1.00 22.34 ? 455 SER A OG 1 ATOM 2036 N N . GLY A 1 266 ? 97.516 4.357 66.488 1.00 19.65 ? 456 GLY A N 1 ATOM 2037 C CA . GLY A 1 266 ? 96.754 5.473 67.009 1.00 19.05 ? 456 GLY A CA 1 ATOM 2038 C C . GLY A 1 266 ? 96.599 6.659 66.071 1.00 23.78 ? 456 GLY A C 1 ATOM 2039 O O . GLY A 1 266 ? 95.899 7.613 66.412 1.00 27.21 ? 456 GLY A O 1 ATOM 2040 N N . THR A 1 267 ? 97.239 6.632 64.905 1.00 22.17 ? 457 THR A N 1 ATOM 2041 C CA . THR A 1 267 ? 97.088 7.754 63.981 1.00 28.93 ? 457 THR A CA 1 ATOM 2042 C C . THR A 1 267 ? 95.726 7.660 63.300 1.00 31.56 ? 457 THR A C 1 ATOM 2043 O O . THR A 1 267 ? 95.357 6.620 62.744 1.00 30.60 ? 457 THR A O 1 ATOM 2044 C CB . THR A 1 267 ? 98.204 7.796 62.897 1.00 26.48 ? 457 THR A CB 1 ATOM 2045 O OG1 . THR A 1 267 ? 98.171 6.600 62.114 1.00 31.56 ? 457 THR A OG1 1 ATOM 2046 C CG2 . THR A 1 267 ? 99.573 7.944 63.546 1.00 28.52 ? 457 THR A CG2 1 ATOM 2047 N N . GLU A 1 268 ? 94.979 8.756 63.364 1.00 30.39 ? 458 GLU A N 1 ATOM 2048 C CA . GLU A 1 268 ? 93.647 8.828 62.782 1.00 27.55 ? 458 GLU A CA 1 ATOM 2049 C C . GLU A 1 268 ? 93.654 8.573 61.281 1.00 25.05 ? 458 GLU A C 1 ATOM 2050 O O . GLU A 1 268 ? 94.348 9.260 60.532 1.00 22.35 ? 458 GLU A O 1 ATOM 2051 C CB . GLU A 1 268 ? 93.038 10.201 63.082 1.00 25.90 ? 458 GLU A CB 1 ATOM 2052 C CG . GLU A 1 268 ? 91.653 10.422 62.509 1.00 31.04 ? 458 GLU A CG 1 ATOM 2053 C CD . GLU A 1 268 ? 90.999 11.674 63.061 1.00 32.23 ? 458 GLU A CD 1 ATOM 2054 O OE1 . GLU A 1 268 ? 90.741 11.715 64.284 1.00 34.43 ? 458 GLU A OE1 1 ATOM 2055 O OE2 . GLU A 1 268 ? 90.748 12.614 62.278 1.00 28.42 ? 458 GLU A OE2 1 ATOM 2056 N N . CYS A 1 269 ? 92.882 7.581 60.844 1.00 24.65 ? 459 CYS A N 1 ATOM 2057 C CA . CYS A 1 269 ? 92.809 7.264 59.425 1.00 20.99 ? 459 CYS A CA 1 ATOM 2058 C C . CYS A 1 269 ? 91.432 7.509 58.809 1.00 24.51 ? 459 CYS A C 1 ATOM 2059 O O . CYS A 1 269 ? 91.288 7.528 57.584 1.00 27.39 ? 459 CYS A O 1 ATOM 2060 C CB . CYS A 1 269 ? 93.276 5.831 59.169 1.00 17.73 ? 459 CYS A CB 1 ATOM 2061 S SG . CYS A 1 269 ? 92.512 4.496 60.139 1.00 25.46 ? 459 CYS A SG 1 ATOM 2062 N N . ARG A 1 270 ? 90.420 7.683 59.653 1.00 21.26 ? 460 ARG A N 1 ATOM 2063 C CA . ARG A 1 270 ? 89.081 7.998 59.169 1.00 18.98 ? 460 ARG A CA 1 ATOM 2064 C C . ARG A 1 270 ? 88.455 8.970 60.159 1.00 20.27 ? 460 ARG A C 1 ATOM 2065 O O . ARG A 1 270 ? 88.018 8.582 61.244 1.00 15.20 ? 460 ARG A O 1 ATOM 2066 C CB . ARG A 1 270 ? 88.200 6.753 59.023 1.00 20.33 ? 460 ARG A CB 1 ATOM 2067 C CG . ARG A 1 270 ? 86.895 7.067 58.277 1.00 19.68 ? 460 ARG A CG 1 ATOM 2068 C CD . ARG A 1 270 ? 85.929 5.886 58.167 1.00 23.15 ? 460 ARG A CD 1 ATOM 2069 N NE . ARG A 1 270 ? 86.480 4.763 57.410 1.00 19.51 ? 460 ARG A NE 1 ATOM 2070 C CZ . ARG A 1 270 ? 87.163 3.761 57.952 1.00 21.49 ? 460 ARG A CZ 1 ATOM 2071 N NH1 . ARG A 1 270 ? 87.376 3.739 59.260 1.00 27.38 ? 460 ARG A NH1 1 ATOM 2072 N NH2 . ARG A 1 270 ? 87.637 2.784 57.189 1.00 13.11 ? 460 ARG A NH2 1 ATOM 2073 N N . ALA A 1 271 ? 88.433 10.241 59.773 1.00 19.65 ? 461 ALA A N 1 ATOM 2074 C CA . ALA A 1 271 ? 87.893 11.308 60.601 1.00 21.71 ? 461 ALA A CA 1 ATOM 2075 C C . ALA A 1 271 ? 86.457 11.078 61.064 1.00 25.76 ? 461 ALA A C 1 ATOM 2076 O O . ALA A 1 271 ? 85.700 10.329 60.448 1.00 26.31 ? 461 ALA A O 1 ATOM 2077 C CB . ALA A 1 271 ? 87.989 12.626 59.853 1.00 19.59 ? 461 ALA A CB 1 ATOM 2078 N N . SER A 1 272 ? 86.099 11.745 62.158 1.00 27.22 ? 462 SER A N 1 ATOM 2079 C CA . SER A 1 272 ? 84.768 11.653 62.748 1.00 29.68 ? 462 SER A CA 1 ATOM 2080 C C . SER A 1 272 ? 83.795 12.673 62.147 1.00 31.87 ? 462 SER A C 1 ATOM 2081 O O . SER A 1 272 ? 84.038 13.883 62.202 1.00 26.91 ? 462 SER A O 1 ATOM 2082 C CB . SER A 1 272 ? 84.869 11.869 64.265 1.00 31.56 ? 462 SER A CB 1 ATOM 2083 O OG . SER A 1 272 ? 83.599 12.094 64.857 1.00 30.01 ? 462 SER A OG 1 ATOM 2084 N N . MET A 1 273 ? 82.697 12.184 61.574 1.00 31.53 ? 463 MET A N 1 ATOM 2085 C CA . MET A 1 273 ? 81.692 13.067 60.988 1.00 34.67 ? 463 MET A CA 1 ATOM 2086 C C . MET A 1 273 ? 81.068 13.922 62.096 1.00 33.45 ? 463 MET A C 1 ATOM 2087 O O . MET A 1 273 ? 80.954 15.141 61.965 1.00 35.14 ? 463 MET A O 1 ATOM 2088 C CB . MET A 1 273 ? 80.596 12.251 60.287 1.00 34.44 ? 463 MET A CB 1 ATOM 2089 C CG . MET A 1 273 ? 81.047 11.491 59.044 1.00 36.56 ? 463 MET A CG 1 ATOM 2090 S SD . MET A 1 273 ? 79.717 10.479 58.308 1.00 44.80 ? 463 MET A SD 1 ATOM 2091 C CE . MET A 1 273 ? 78.937 11.673 57.204 1.00 37.66 ? 463 MET A CE 1 ATOM 2092 N N . SER A 1 274 ? 80.672 13.267 63.183 1.00 30.19 ? 464 SER A N 1 ATOM 2093 C CA . SER A 1 274 ? 80.062 13.933 64.332 1.00 26.28 ? 464 SER A CA 1 ATOM 2094 C C . SER A 1 274 ? 80.272 13.052 65.556 1.00 25.04 ? 464 SER A C 1 ATOM 2095 O O . SER A 1 274 ? 80.919 12.010 65.465 1.00 27.85 ? 464 SER A O 1 ATOM 2096 C CB . SER A 1 274 ? 78.559 14.138 64.105 1.00 28.05 ? 464 SER A CB 1 ATOM 2097 O OG . SER A 1 274 ? 77.862 12.902 64.083 1.00 18.04 ? 464 SER A OG 1 ATOM 2098 N N . GLU A 1 275 ? 79.723 13.463 66.696 1.00 20.00 ? 465 GLU A N 1 ATOM 2099 C CA . GLU A 1 275 ? 79.865 12.684 67.921 1.00 22.15 ? 465 GLU A CA 1 ATOM 2100 C C . GLU A 1 275 ? 79.295 11.278 67.754 1.00 24.04 ? 465 GLU A C 1 ATOM 2101 O O . GLU A 1 275 ? 79.692 10.353 68.456 1.00 32.06 ? 465 GLU A O 1 ATOM 2102 C CB . GLU A 1 275 ? 79.165 13.385 69.084 1.00 22.01 ? 465 GLU A CB 1 ATOM 2103 C CG . GLU A 1 275 ? 77.672 13.549 68.897 1.00 31.73 ? 465 GLU A CG 1 ATOM 2104 C CD . GLU A 1 275 ? 77.041 14.383 69.993 1.00 37.81 ? 465 GLU A CD 1 ATOM 2105 O OE1 . GLU A 1 275 ? 76.902 13.881 71.130 1.00 35.52 ? 465 GLU A OE1 1 ATOM 2106 O OE2 . GLU A 1 275 ? 76.692 15.551 69.716 1.00 44.11 ? 465 GLU A OE2 1 ATOM 2107 N N . CYS A 1 276 ? 78.364 11.120 66.821 1.00 24.36 ? 466 CYS A N 1 ATOM 2108 C CA . CYS A 1 276 ? 77.750 9.822 66.567 1.00 18.41 ? 466 CYS A CA 1 ATOM 2109 C C . CYS A 1 276 ? 78.640 8.945 65.699 1.00 16.28 ? 466 CYS A C 1 ATOM 2110 O O . CYS A 1 276 ? 78.305 7.790 65.428 1.00 13.67 ? 466 CYS A O 1 ATOM 2111 C CB . CYS A 1 276 ? 76.411 9.995 65.859 1.00 21.26 ? 466 CYS A CB 1 ATOM 2112 S SG . CYS A 1 276 ? 75.102 10.833 66.802 1.00 29.17 ? 466 CYS A SG 1 ATOM 2113 N N . ASP A 1 277 ? 79.766 9.498 65.256 1.00 15.28 ? 467 ASP A N 1 ATOM 2114 C CA . ASP A 1 277 ? 80.701 8.760 64.407 1.00 17.59 ? 467 ASP A CA 1 ATOM 2115 C C . ASP A 1 277 ? 82.109 8.667 64.993 1.00 14.95 ? 467 ASP A C 1 ATOM 2116 O O . ASP A 1 277 ? 82.966 9.499 64.696 1.00 15.84 ? 467 ASP A O 1 ATOM 2117 C CB . ASP A 1 277 ? 80.786 9.416 63.026 1.00 19.07 ? 467 ASP A CB 1 ATOM 2118 C CG . ASP A 1 277 ? 81.763 8.711 62.102 1.00 18.74 ? 467 ASP A CG 1 ATOM 2119 O OD1 . ASP A 1 277 ? 82.165 9.317 61.086 1.00 23.85 ? 467 ASP A OD1 1 ATOM 2120 O OD2 . ASP A 1 277 ? 82.125 7.549 62.386 1.00 18.09 ? 467 ASP A OD2 1 ATOM 2121 N N . PRO A 1 278 ? 82.372 7.652 65.830 1.00 13.50 ? 468 PRO A N 1 ATOM 2122 C CA . PRO A 1 278 ? 83.717 7.537 66.402 1.00 11.86 ? 468 PRO A CA 1 ATOM 2123 C C . PRO A 1 278 ? 84.748 7.298 65.307 1.00 10.40 ? 468 PRO A C 1 ATOM 2124 O O . PRO A 1 278 ? 84.595 6.403 64.480 1.00 15.37 ? 468 PRO A O 1 ATOM 2125 C CB . PRO A 1 278 ? 83.589 6.347 67.354 1.00 9.61 ? 468 PRO A CB 1 ATOM 2126 C CG . PRO A 1 278 ? 82.540 5.498 66.698 1.00 7.99 ? 468 PRO A CG 1 ATOM 2127 C CD . PRO A 1 278 ? 81.518 6.529 66.257 1.00 14.64 ? 468 PRO A CD 1 ATOM 2128 N N . ALA A 1 279 ? 85.795 8.110 65.293 1.00 9.15 ? 469 ALA A N 1 ATOM 2129 C CA . ALA A 1 279 ? 86.831 7.964 64.287 1.00 10.24 ? 469 ALA A CA 1 ATOM 2130 C C . ALA A 1 279 ? 87.588 6.660 64.485 1.00 13.39 ? 469 ALA A C 1 ATOM 2131 O O . ALA A 1 279 ? 87.553 6.064 65.559 1.00 16.40 ? 469 ALA A O 1 ATOM 2132 C CB . ALA A 1 279 ? 87.795 9.135 64.360 1.00 11.54 ? 469 ALA A CB 1 ATOM 2133 N N . GLU A 1 280 ? 88.257 6.210 63.432 1.00 15.79 ? 470 GLU A N 1 ATOM 2134 C CA . GLU A 1 280 ? 89.053 4.999 63.508 1.00 19.63 ? 470 GLU A CA 1 ATOM 2135 C C . GLU A 1 280 ? 90.521 5.404 63.479 1.00 23.83 ? 470 GLU A C 1 ATOM 2136 O O . GLU A 1 280 ? 90.876 6.451 62.924 1.00 19.84 ? 470 GLU A O 1 ATOM 2137 C CB . GLU A 1 280 ? 88.732 4.061 62.342 1.00 22.03 ? 470 GLU A CB 1 ATOM 2138 C CG . GLU A 1 280 ? 87.383 3.368 62.476 1.00 28.72 ? 470 GLU A CG 1 ATOM 2139 C CD . GLU A 1 280 ? 86.215 4.303 62.242 1.00 32.37 ? 470 GLU A CD 1 ATOM 2140 O OE1 . GLU A 1 280 ? 85.116 4.019 62.760 1.00 32.45 ? 470 GLU A OE1 1 ATOM 2141 O OE2 . GLU A 1 280 ? 86.391 5.312 61.528 1.00 33.72 ? 470 GLU A OE2 1 ATOM 2142 N N . HIS A 1 281 ? 91.371 4.582 64.084 1.00 23.79 ? 471 HIS A N 1 ATOM 2143 C CA . HIS A 1 281 ? 92.797 4.876 64.136 1.00 24.79 ? 471 HIS A CA 1 ATOM 2144 C C . HIS A 1 281 ? 93.608 3.667 63.678 1.00 25.21 ? 471 HIS A C 1 ATOM 2145 O O . HIS A 1 281 ? 93.169 2.523 63.831 1.00 23.35 ? 471 HIS A O 1 ATOM 2146 C CB . HIS A 1 281 ? 93.176 5.273 65.564 1.00 26.62 ? 471 HIS A CB 1 ATOM 2147 C CG . HIS A 1 281 ? 92.303 6.347 66.138 1.00 32.69 ? 471 HIS A CG 1 ATOM 2148 N ND1 . HIS A 1 281 ? 92.346 7.655 65.703 1.00 37.26 ? 471 HIS A ND1 1 ATOM 2149 C CD2 . HIS A 1 281 ? 91.337 6.299 67.087 1.00 34.88 ? 471 HIS A CD2 1 ATOM 2150 C CE1 . HIS A 1 281 ? 91.445 8.366 66.358 1.00 31.98 ? 471 HIS A CE1 1 ATOM 2151 N NE2 . HIS A 1 281 ? 90.819 7.567 67.204 1.00 33.94 ? 471 HIS A NE2 1 ATOM 2152 N N . CYS A 1 282 ? 94.784 3.923 63.107 1.00 21.82 ? 472 CYS A N 1 ATOM 2153 C CA . CYS A 1 282 ? 95.643 2.844 62.629 1.00 18.88 ? 472 CYS A CA 1 ATOM 2154 C C . CYS A 1 282 ? 96.138 2.002 63.800 1.00 17.85 ? 472 CYS A C 1 ATOM 2155 O O . CYS A 1 282 ? 96.305 2.505 64.914 1.00 14.50 ? 472 CYS A O 1 ATOM 2156 C CB . CYS A 1 282 ? 96.837 3.410 61.855 1.00 20.07 ? 472 CYS A CB 1 ATOM 2157 S SG . CYS A 1 282 ? 96.399 4.421 60.398 1.00 27.44 ? 472 CYS A SG 1 ATOM 2158 N N . THR A 1 283 ? 96.367 0.718 63.546 1.00 15.45 ? 473 THR A N 1 ATOM 2159 C CA . THR A 1 283 ? 96.841 -0.190 64.584 1.00 18.73 ? 473 THR A CA 1 ATOM 2160 C C . THR A 1 283 ? 98.362 -0.128 64.727 1.00 21.12 ? 473 THR A C 1 ATOM 2161 O O . THR A 1 283 ? 98.902 -0.291 65.820 1.00 19.68 ? 473 THR A O 1 ATOM 2162 C CB . THR A 1 283 ? 96.449 -1.650 64.274 1.00 18.76 ? 473 THR A CB 1 ATOM 2163 O OG1 . THR A 1 283 ? 97.134 -2.092 63.094 1.00 22.73 ? 473 THR A OG1 1 ATOM 2164 C CG2 . THR A 1 283 ? 94.956 -1.765 64.052 1.00 11.73 ? 473 THR A CG2 1 ATOM 2165 N N . GLY A 1 284 ? 99.046 0.114 63.615 1.00 20.70 ? 474 GLY A N 1 ATOM 2166 C CA . GLY A 1 284 ? 100.494 0.170 63.639 1.00 21.64 ? 474 GLY A CA 1 ATOM 2167 C C . GLY A 1 284 ? 101.034 -1.147 63.120 1.00 23.19 ? 474 GLY A C 1 ATOM 2168 O O . GLY A 1 284 ? 102.238 -1.319 62.939 1.00 25.39 ? 474 GLY A O 1 ATOM 2169 N N . GLN A 1 285 ? 100.122 -2.079 62.871 1.00 23.67 ? 475 GLN A N 1 ATOM 2170 C CA . GLN A 1 285 ? 100.480 -3.397 62.371 1.00 26.52 ? 475 GLN A CA 1 ATOM 2171 C C . GLN A 1 285 ? 99.984 -3.628 60.950 1.00 23.91 ? 475 GLN A C 1 ATOM 2172 O O . GLN A 1 285 ? 100.378 -4.595 60.301 1.00 24.21 ? 475 GLN A O 1 ATOM 2173 C CB . GLN A 1 285 ? 99.900 -4.474 63.284 1.00 30.52 ? 475 GLN A CB 1 ATOM 2174 C CG . GLN A 1 285 ? 100.549 -4.546 64.645 1.00 39.84 ? 475 GLN A CG 1 ATOM 2175 C CD . GLN A 1 285 ? 99.903 -5.592 65.530 1.00 49.69 ? 475 GLN A CD 1 ATOM 2176 O OE1 . GLN A 1 285 ? 98.777 -5.416 66.002 1.00 50.40 ? 475 GLN A OE1 1 ATOM 2177 N NE2 . GLN A 1 285 ? 100.609 -6.697 65.750 1.00 52.82 ? 475 GLN A NE2 1 ATOM 2178 N N . SER A 1 286 ? 99.126 -2.740 60.466 1.00 23.03 ? 476 SER A N 1 ATOM 2179 C CA . SER A 1 286 ? 98.579 -2.881 59.124 1.00 23.37 ? 476 SER A CA 1 ATOM 2180 C C . SER A 1 286 ? 98.557 -1.570 58.347 1.00 23.41 ? 476 SER A C 1 ATOM 2181 O O . SER A 1 286 ? 98.707 -0.489 58.916 1.00 24.46 ? 476 SER A O 1 ATOM 2182 C CB . SER A 1 286 ? 97.158 -3.445 59.209 1.00 27.57 ? 476 SER A CB 1 ATOM 2183 O OG . SER A 1 286 ? 96.553 -3.508 57.929 1.00 36.73 ? 476 SER A OG 1 ATOM 2184 N N . SER A 1 287 ? 98.372 -1.673 57.038 1.00 21.15 ? 477 SER A N 1 ATOM 2185 C CA . SER A 1 287 ? 98.311 -0.491 56.196 1.00 24.56 ? 477 SER A CA 1 ATOM 2186 C C . SER A 1 287 ? 96.847 -0.138 55.956 1.00 25.95 ? 477 SER A C 1 ATOM 2187 O O . SER A 1 287 ? 96.532 0.909 55.390 1.00 25.33 ? 477 SER A O 1 ATOM 2188 C CB . SER A 1 287 ? 99.013 -0.755 54.865 1.00 24.31 ? 477 SER A CB 1 ATOM 2189 O OG . SER A 1 287 ? 98.459 -1.883 54.215 1.00 29.68 ? 477 SER A OG 1 ATOM 2190 N N . GLU A 1 288 ? 95.957 -1.021 56.398 1.00 27.84 ? 478 GLU A N 1 ATOM 2191 C CA . GLU A 1 288 ? 94.522 -0.822 56.234 1.00 29.25 ? 478 GLU A CA 1 ATOM 2192 C C . GLU A 1 288 ? 93.895 -0.176 57.455 1.00 28.06 ? 478 GLU A C 1 ATOM 2193 O O . GLU A 1 288 ? 94.251 -0.479 58.592 1.00 32.12 ? 478 GLU A O 1 ATOM 2194 C CB . GLU A 1 288 ? 93.821 -2.155 55.962 1.00 34.11 ? 478 GLU A CB 1 ATOM 2195 C CG . GLU A 1 288 ? 94.138 -2.783 54.617 1.00 45.02 ? 478 GLU A CG 1 ATOM 2196 C CD . GLU A 1 288 ? 93.783 -1.877 53.452 1.00 55.02 ? 478 GLU A CD 1 ATOM 2197 O OE1 . GLU A 1 288 ? 94.567 -0.951 53.149 1.00 56.24 ? 478 GLU A OE1 1 ATOM 2198 O OE2 . GLU A 1 288 ? 92.712 -2.088 52.843 1.00 62.41 ? 478 GLU A OE2 1 ATOM 2199 N N . CYS A 1 289 ? 92.948 0.716 57.206 1.00 27.16 ? 479 CYS A N 1 ATOM 2200 C CA . CYS A 1 289 ? 92.248 1.413 58.270 1.00 23.10 ? 479 CYS A CA 1 ATOM 2201 C C . CYS A 1 289 ? 91.058 0.569 58.703 1.00 21.12 ? 479 CYS A C 1 ATOM 2202 O O . CYS A 1 289 ? 90.281 0.103 57.868 1.00 18.42 ? 479 CYS A O 1 ATOM 2203 C CB . CYS A 1 289 ? 91.771 2.767 57.752 1.00 23.63 ? 479 CYS A CB 1 ATOM 2204 S SG . CYS A 1 289 ? 90.977 3.881 58.953 1.00 34.01 ? 479 CYS A SG 1 ATOM 2205 N N . PRO A 1 290 ? 90.901 0.355 60.018 1.00 19.99 ? 480 PRO A N 1 ATOM 2206 C CA . PRO A 1 290 ? 89.786 -0.443 60.538 1.00 15.37 ? 480 PRO A CA 1 ATOM 2207 C C . PRO A 1 290 ? 88.413 -0.008 60.018 1.00 14.05 ? 480 PRO A C 1 ATOM 2208 O O . PRO A 1 290 ? 88.206 1.154 59.659 1.00 11.92 ? 480 PRO A O 1 ATOM 2209 C CB . PRO A 1 290 ? 89.924 -0.288 62.055 1.00 12.52 ? 480 PRO A CB 1 ATOM 2210 C CG . PRO A 1 290 ? 90.660 1.007 62.212 1.00 19.96 ? 480 PRO A CG 1 ATOM 2211 C CD . PRO A 1 290 ? 91.690 0.923 61.123 1.00 14.18 ? 480 PRO A CD 1 ATOM 2212 N N . ALA A 1 291 ? 87.485 -0.960 59.979 1.00 11.80 ? 481 ALA A N 1 ATOM 2213 C CA . ALA A 1 291 ? 86.129 -0.728 59.500 1.00 12.40 ? 481 ALA A CA 1 ATOM 2214 C C . ALA A 1 291 ? 85.464 0.482 60.149 1.00 16.05 ? 481 ALA A C 1 ATOM 2215 O O . ALA A 1 291 ? 85.727 0.812 61.306 1.00 16.66 ? 481 ALA A O 1 ATOM 2216 C CB . ALA A 1 291 ? 85.287 -1.968 59.733 1.00 12.71 ? 481 ALA A CB 1 ATOM 2217 N N . ASP A 1 292 ? 84.592 1.136 59.391 1.00 16.73 ? 482 ASP A N 1 ATOM 2218 C CA . ASP A 1 292 ? 83.888 2.310 59.886 1.00 17.96 ? 482 ASP A CA 1 ATOM 2219 C C . ASP A 1 292 ? 82.814 1.902 60.891 1.00 18.51 ? 482 ASP A C 1 ATOM 2220 O O . ASP A 1 292 ? 81.914 1.121 60.582 1.00 20.44 ? 482 ASP A O 1 ATOM 2221 C CB . ASP A 1 292 ? 83.257 3.076 58.716 1.00 13.82 ? 482 ASP A CB 1 ATOM 2222 C CG . ASP A 1 292 ? 82.889 4.505 59.081 1.00 18.46 ? 482 ASP A CG 1 ATOM 2223 O OD1 . ASP A 1 292 ? 82.498 5.268 58.169 1.00 18.19 ? 482 ASP A OD1 1 ATOM 2224 O OD2 . ASP A 1 292 ? 82.988 4.867 60.274 1.00 10.02 ? 482 ASP A OD2 1 ATOM 2225 N N . VAL A 1 293 ? 82.928 2.429 62.103 1.00 18.33 ? 483 VAL A N 1 ATOM 2226 C CA . VAL A 1 293 ? 81.976 2.137 63.161 1.00 13.17 ? 483 VAL A CA 1 ATOM 2227 C C . VAL A 1 293 ? 81.135 3.366 63.483 1.00 16.08 ? 483 VAL A C 1 ATOM 2228 O O . VAL A 1 293 ? 81.642 4.490 63.547 1.00 12.02 ? 483 VAL A O 1 ATOM 2229 C CB . VAL A 1 293 ? 82.697 1.673 64.455 1.00 14.41 ? 483 VAL A CB 1 ATOM 2230 C CG1 . VAL A 1 293 ? 81.699 1.592 65.615 1.00 11.25 ? 483 VAL A CG1 1 ATOM 2231 C CG2 . VAL A 1 293 ? 83.352 0.316 64.228 1.00 1.00 ? 483 VAL A CG2 1 ATOM 2232 N N . PHE A 1 294 ? 79.843 3.136 63.685 1.00 15.41 ? 484 PHE A N 1 ATOM 2233 C CA . PHE A 1 294 ? 78.906 4.198 64.015 1.00 15.39 ? 484 PHE A CA 1 ATOM 2234 C C . PHE A 1 294 ? 78.301 3.887 65.371 1.00 14.10 ? 484 PHE A C 1 ATOM 2235 O O . PHE A 1 294 ? 78.180 2.721 65.738 1.00 17.82 ? 484 PHE A O 1 ATOM 2236 C CB . PHE A 1 294 ? 77.769 4.250 62.985 1.00 12.92 ? 484 PHE A CB 1 ATOM 2237 C CG . PHE A 1 294 ? 78.155 4.851 61.661 1.00 16.75 ? 484 PHE A CG 1 ATOM 2238 C CD1 . PHE A 1 294 ? 77.279 4.777 60.580 1.00 14.48 ? 484 PHE A CD1 1 ATOM 2239 C CD2 . PHE A 1 294 ? 79.375 5.502 61.492 1.00 15.07 ? 484 PHE A CD2 1 ATOM 2240 C CE1 . PHE A 1 294 ? 77.613 5.341 59.350 1.00 9.74 ? 484 PHE A CE1 1 ATOM 2241 C CE2 . PHE A 1 294 ? 79.716 6.068 60.267 1.00 10.84 ? 484 PHE A CE2 1 ATOM 2242 C CZ . PHE A 1 294 ? 78.831 5.987 59.194 1.00 6.93 ? 484 PHE A CZ 1 ATOM 2243 N N . HIS A 1 295 ? 77.932 4.916 66.125 1.00 12.28 ? 485 HIS A N 1 ATOM 2244 C CA . HIS A 1 295 ? 77.280 4.669 67.400 1.00 16.43 ? 485 HIS A CA 1 ATOM 2245 C C . HIS A 1 295 ? 75.845 4.272 67.039 1.00 17.05 ? 485 HIS A C 1 ATOM 2246 O O . HIS A 1 295 ? 75.398 4.500 65.913 1.00 20.56 ? 485 HIS A O 1 ATOM 2247 C CB . HIS A 1 295 ? 77.290 5.922 68.282 1.00 16.73 ? 485 HIS A CB 1 ATOM 2248 C CG . HIS A 1 295 ? 78.638 6.251 68.847 1.00 22.26 ? 485 HIS A CG 1 ATOM 2249 N ND1 . HIS A 1 295 ? 79.469 5.298 69.396 1.00 19.46 ? 485 HIS A ND1 1 ATOM 2250 C CD2 . HIS A 1 295 ? 79.293 7.431 68.966 1.00 24.79 ? 485 HIS A CD2 1 ATOM 2251 C CE1 . HIS A 1 295 ? 80.575 5.876 69.827 1.00 22.77 ? 485 HIS A CE1 1 ATOM 2252 N NE2 . HIS A 1 295 ? 80.494 7.170 69.578 1.00 19.75 ? 485 HIS A NE2 1 ATOM 2253 N N . LYS A 1 296 ? 75.124 3.679 67.981 1.00 17.35 ? 486 LYS A N 1 ATOM 2254 C CA . LYS A 1 296 ? 73.757 3.244 67.713 1.00 10.91 ? 486 LYS A CA 1 ATOM 2255 C C . LYS A 1 296 ? 72.818 4.366 67.293 1.00 8.88 ? 486 LYS A C 1 ATOM 2256 O O . LYS A 1 296 ? 72.885 5.475 67.815 1.00 14.32 ? 486 LYS A O 1 ATOM 2257 C CB . LYS A 1 296 ? 73.181 2.536 68.941 1.00 6.72 ? 486 LYS A CB 1 ATOM 2258 C CG . LYS A 1 296 ? 73.929 1.270 69.326 1.00 4.91 ? 486 LYS A CG 1 ATOM 2259 C CD . LYS A 1 296 ? 73.365 0.665 70.596 1.00 1.00 ? 486 LYS A CD 1 ATOM 2260 C CE . LYS A 1 296 ? 74.058 -0.629 70.934 1.00 1.00 ? 486 LYS A CE 1 ATOM 2261 N NZ . LYS A 1 296 ? 73.454 -1.295 72.117 1.00 16.44 ? 486 LYS A NZ 1 ATOM 2262 N N . ASN A 1 297 ? 71.946 4.067 66.337 1.00 9.72 ? 487 ASN A N 1 ATOM 2263 C CA . ASN A 1 297 ? 70.962 5.033 65.867 1.00 8.51 ? 487 ASN A CA 1 ATOM 2264 C C . ASN A 1 297 ? 69.957 5.215 66.995 1.00 6.48 ? 487 ASN A C 1 ATOM 2265 O O . ASN A 1 297 ? 69.628 4.255 67.686 1.00 2.74 ? 487 ASN A O 1 ATOM 2266 C CB . ASN A 1 297 ? 70.235 4.502 64.625 1.00 6.92 ? 487 ASN A CB 1 ATOM 2267 C CG . ASN A 1 297 ? 71.108 4.509 63.383 1.00 10.91 ? 487 ASN A CG 1 ATOM 2268 O OD1 . ASN A 1 297 ? 70.728 3.971 62.343 1.00 11.93 ? 487 ASN A OD1 1 ATOM 2269 N ND2 . ASN A 1 297 ? 72.281 5.127 63.482 1.00 23.11 ? 487 ASN A ND2 1 ATOM 2270 N N . GLY A 1 298 ? 69.475 6.440 67.182 1.00 10.72 ? 488 GLY A N 1 ATOM 2271 C CA . GLY A 1 298 ? 68.509 6.698 68.235 1.00 9.81 ? 488 GLY A CA 1 ATOM 2272 C C . GLY A 1 298 ? 69.156 7.173 69.520 1.00 13.79 ? 488 GLY A C 1 ATOM 2273 O O . GLY A 1 298 ? 68.471 7.576 70.462 1.00 12.81 ? 488 GLY A O 1 ATOM 2274 N N . GLN A 1 299 ? 70.482 7.116 69.567 1.00 16.06 ? 489 GLN A N 1 ATOM 2275 C CA . GLN A 1 299 ? 71.211 7.559 70.742 1.00 17.64 ? 489 GLN A CA 1 ATOM 2276 C C . GLN A 1 299 ? 71.197 9.080 70.788 1.00 18.76 ? 489 GLN A C 1 ATOM 2277 O O . GLN A 1 299 ? 71.507 9.740 69.797 1.00 19.81 ? 489 GLN A O 1 ATOM 2278 C CB . GLN A 1 299 ? 72.655 7.056 70.695 1.00 18.86 ? 489 GLN A CB 1 ATOM 2279 C CG . GLN A 1 299 ? 73.538 7.657 71.777 1.00 29.67 ? 489 GLN A CG 1 ATOM 2280 C CD . GLN A 1 299 ? 74.887 6.980 71.876 1.00 39.54 ? 489 GLN A CD 1 ATOM 2281 O OE1 . GLN A 1 299 ? 74.976 5.793 72.195 1.00 49.51 ? 489 GLN A OE1 1 ATOM 2282 N NE2 . GLN A 1 299 ? 75.948 7.729 71.601 1.00 47.53 ? 489 GLN A NE2 1 ATOM 2283 N N . PRO A 1 300 ? 70.814 9.661 71.936 1.00 20.88 ? 490 PRO A N 1 ATOM 2284 C CA . PRO A 1 300 ? 70.781 11.121 72.047 1.00 21.60 ? 490 PRO A CA 1 ATOM 2285 C C . PRO A 1 300 ? 72.134 11.741 71.707 1.00 23.22 ? 490 PRO A C 1 ATOM 2286 O O . PRO A 1 300 ? 73.182 11.209 72.082 1.00 23.23 ? 490 PRO A O 1 ATOM 2287 C CB . PRO A 1 300 ? 70.378 11.339 73.500 1.00 18.44 ? 490 PRO A CB 1 ATOM 2288 C CG . PRO A 1 300 ? 69.440 10.203 73.741 1.00 10.84 ? 490 PRO A CG 1 ATOM 2289 C CD . PRO A 1 300 ? 70.189 9.036 73.116 1.00 21.97 ? 490 PRO A CD 1 ATOM 2290 N N . CYS A 1 301 ? 72.101 12.861 70.991 1.00 20.15 ? 491 CYS A N 1 ATOM 2291 C CA . CYS A 1 301 ? 73.319 13.551 70.585 1.00 18.79 ? 491 CYS A CA 1 ATOM 2292 C C . CYS A 1 301 ? 73.151 15.074 70.587 1.00 17.77 ? 491 CYS A C 1 ATOM 2293 O O . CYS A 1 301 ? 72.034 15.586 70.642 1.00 17.20 ? 491 CYS A O 1 ATOM 2294 C CB . CYS A 1 301 ? 73.745 13.065 69.195 1.00 22.15 ? 491 CYS A CB 1 ATOM 2295 S SG . CYS A 1 301 ? 72.445 13.151 67.915 1.00 27.24 ? 491 CYS A SG 1 ATOM 2296 N N . LEU A 1 302 ? 74.272 15.786 70.525 1.00 15.95 ? 492 LEU A N 1 ATOM 2297 C CA . LEU A 1 302 ? 74.278 17.244 70.535 1.00 20.49 ? 492 LEU A CA 1 ATOM 2298 C C . LEU A 1 302 ? 73.457 17.813 71.689 1.00 25.43 ? 492 LEU A C 1 ATOM 2299 O O . LEU A 1 302 ? 72.493 18.558 71.482 1.00 22.11 ? 492 LEU A O 1 ATOM 2300 C CB . LEU A 1 302 ? 73.769 17.795 69.196 1.00 20.21 ? 492 LEU A CB 1 ATOM 2301 C CG . LEU A 1 302 ? 74.707 17.620 67.993 1.00 19.41 ? 492 LEU A CG 1 ATOM 2302 C CD1 . LEU A 1 302 ? 74.053 18.172 66.724 1.00 11.69 ? 492 LEU A CD1 1 ATOM 2303 C CD2 . LEU A 1 302 ? 76.023 18.341 68.271 1.00 11.19 ? 492 LEU A CD2 1 ATOM 2304 N N . ASP A 1 303 ? 73.857 17.455 72.908 1.00 31.31 ? 493 ASP A N 1 ATOM 2305 C CA . ASP A 1 303 ? 73.189 17.912 74.124 1.00 39.90 ? 493 ASP A CA 1 ATOM 2306 C C . ASP A 1 303 ? 71.678 17.709 74.081 1.00 40.91 ? 493 ASP A C 1 ATOM 2307 O O . ASP A 1 303 ? 70.902 18.633 74.332 1.00 40.76 ? 493 ASP A O 1 ATOM 2308 C CB . ASP A 1 303 ? 73.509 19.386 74.375 1.00 43.77 ? 493 ASP A CB 1 ATOM 2309 C CG . ASP A 1 303 ? 74.976 19.615 74.670 1.00 46.50 ? 493 ASP A CG 1 ATOM 2310 O OD1 . ASP A 1 303 ? 75.448 19.149 75.730 1.00 48.93 ? 493 ASP A OD1 1 ATOM 2311 O OD2 . ASP A 1 303 ? 75.657 20.253 73.840 1.00 46.05 ? 493 ASP A OD2 1 ATOM 2312 N N . ASN A 1 304 ? 71.276 16.484 73.764 1.00 40.44 ? 494 ASN A N 1 ATOM 2313 C CA . ASN A 1 304 ? 69.871 16.115 73.685 1.00 40.10 ? 494 ASN A CA 1 ATOM 2314 C C . ASN A 1 304 ? 69.032 16.959 72.738 1.00 36.34 ? 494 ASN A C 1 ATOM 2315 O O . ASN A 1 304 ? 67.901 17.318 73.062 1.00 36.70 ? 494 ASN A O 1 ATOM 2316 C CB . ASN A 1 304 ? 69.240 16.132 75.079 1.00 46.36 ? 494 ASN A CB 1 ATOM 2317 C CG . ASN A 1 304 ? 69.628 14.922 75.903 1.00 53.34 ? 494 ASN A CG 1 ATOM 2318 O OD1 . ASN A 1 304 ? 70.791 14.753 76.273 1.00 58.46 ? 494 ASN A OD1 1 ATOM 2319 N ND2 . ASN A 1 304 ? 68.655 14.065 76.184 1.00 60.18 ? 494 ASN A ND2 1 ATOM 2320 N N . TYR A 1 305 ? 69.585 17.274 71.569 1.00 29.46 ? 495 TYR A N 1 ATOM 2321 C CA . TYR A 1 305 ? 68.854 18.045 70.571 1.00 25.57 ? 495 TYR A CA 1 ATOM 2322 C C . TYR A 1 305 ? 68.530 17.162 69.377 1.00 21.40 ? 495 TYR A C 1 ATOM 2323 O O . TYR A 1 305 ? 67.691 17.500 68.542 1.00 18.14 ? 495 TYR A O 1 ATOM 2324 C CB . TYR A 1 305 ? 69.660 19.260 70.115 1.00 26.60 ? 495 TYR A CB 1 ATOM 2325 C CG . TYR A 1 305 ? 69.363 20.506 70.913 1.00 30.11 ? 495 TYR A CG 1 ATOM 2326 C CD1 . TYR A 1 305 ? 69.727 20.602 72.254 1.00 31.71 ? 495 TYR A CD1 1 ATOM 2327 C CD2 . TYR A 1 305 ? 68.698 21.586 70.330 1.00 34.19 ? 495 TYR A CD2 1 ATOM 2328 C CE1 . TYR A 1 305 ? 69.435 21.742 72.997 1.00 32.40 ? 495 TYR A CE1 1 ATOM 2329 C CE2 . TYR A 1 305 ? 68.400 22.731 71.064 1.00 34.44 ? 495 TYR A CE2 1 ATOM 2330 C CZ . TYR A 1 305 ? 68.773 22.801 72.397 1.00 34.45 ? 495 TYR A CZ 1 ATOM 2331 O OH . TYR A 1 305 ? 68.488 23.929 73.128 1.00 37.41 ? 495 TYR A OH 1 ATOM 2332 N N . GLY A 1 306 ? 69.202 16.022 69.304 1.00 19.09 ? 496 GLY A N 1 ATOM 2333 C CA . GLY A 1 306 ? 68.961 15.099 68.215 1.00 19.93 ? 496 GLY A CA 1 ATOM 2334 C C . GLY A 1 306 ? 69.229 13.669 68.633 1.00 18.25 ? 496 GLY A C 1 ATOM 2335 O O . GLY A 1 306 ? 69.549 13.399 69.788 1.00 19.65 ? 496 GLY A O 1 ATOM 2336 N N . TYR A 1 307 ? 69.076 12.750 67.689 1.00 21.06 ? 497 TYR A N 1 ATOM 2337 C CA . TYR A 1 307 ? 69.332 11.339 67.935 1.00 18.93 ? 497 TYR A CA 1 ATOM 2338 C C . TYR A 1 307 ? 70.217 10.850 66.805 1.00 18.62 ? 497 TYR A C 1 ATOM 2339 O O . TYR A 1 307 ? 70.023 11.224 65.652 1.00 22.88 ? 497 TYR A O 1 ATOM 2340 C CB . TYR A 1 307 ? 68.031 10.540 67.959 1.00 16.05 ? 497 TYR A CB 1 ATOM 2341 C CG . TYR A 1 307 ? 67.085 10.954 69.056 1.00 13.61 ? 497 TYR A CG 1 ATOM 2342 C CD1 . TYR A 1 307 ? 66.128 11.947 68.842 1.00 18.33 ? 497 TYR A CD1 1 ATOM 2343 C CD2 . TYR A 1 307 ? 67.144 10.356 70.315 1.00 12.82 ? 497 TYR A CD2 1 ATOM 2344 C CE1 . TYR A 1 307 ? 65.244 12.331 69.858 1.00 14.35 ? 497 TYR A CE1 1 ATOM 2345 C CE2 . TYR A 1 307 ? 66.270 10.733 71.335 1.00 14.36 ? 497 TYR A CE2 1 ATOM 2346 C CZ . TYR A 1 307 ? 65.322 11.719 71.098 1.00 11.29 ? 497 TYR A CZ 1 ATOM 2347 O OH . TYR A 1 307 ? 64.449 12.084 72.096 1.00 15.91 ? 497 TYR A OH 1 ATOM 2348 N N . CYS A 1 308 ? 71.193 10.018 67.136 1.00 20.65 ? 498 CYS A N 1 ATOM 2349 C CA . CYS A 1 308 ? 72.113 9.510 66.131 1.00 16.65 ? 498 CYS A CA 1 ATOM 2350 C C . CYS A 1 308 ? 71.413 8.802 64.993 1.00 13.04 ? 498 CYS A C 1 ATOM 2351 O O . CYS A 1 308 ? 70.503 8.007 65.207 1.00 15.44 ? 498 CYS A O 1 ATOM 2352 C CB . CYS A 1 308 ? 73.120 8.554 66.765 1.00 15.99 ? 498 CYS A CB 1 ATOM 2353 S SG . CYS A 1 308 ? 74.307 9.331 67.908 1.00 28.90 ? 498 CYS A SG 1 ATOM 2354 N N . TYR A 1 309 ? 71.841 9.106 63.775 1.00 15.51 ? 499 TYR A N 1 ATOM 2355 C CA . TYR A 1 309 ? 71.291 8.474 62.587 1.00 13.91 ? 499 TYR A CA 1 ATOM 2356 C C . TYR A 1 309 ? 72.418 8.246 61.587 1.00 14.12 ? 499 TYR A C 1 ATOM 2357 O O . TYR A 1 309 ? 72.904 9.185 60.958 1.00 12.06 ? 499 TYR A O 1 ATOM 2358 C CB . TYR A 1 309 ? 70.199 9.339 61.948 1.00 14.19 ? 499 TYR A CB 1 ATOM 2359 C CG . TYR A 1 309 ? 69.645 8.729 60.679 1.00 13.80 ? 499 TYR A CG 1 ATOM 2360 C CD1 . TYR A 1 309 ? 69.007 7.489 60.700 1.00 16.16 ? 499 TYR A CD1 1 ATOM 2361 C CD2 . TYR A 1 309 ? 69.816 9.359 59.446 1.00 17.29 ? 499 TYR A CD2 1 ATOM 2362 C CE1 . TYR A 1 309 ? 68.561 6.887 59.525 1.00 19.01 ? 499 TYR A CE1 1 ATOM 2363 C CE2 . TYR A 1 309 ? 69.370 8.768 58.264 1.00 14.94 ? 499 TYR A CE2 1 ATOM 2364 C CZ . TYR A 1 309 ? 68.747 7.532 58.310 1.00 20.21 ? 499 TYR A CZ 1 ATOM 2365 O OH . TYR A 1 309 ? 68.330 6.933 57.143 1.00 20.08 ? 499 TYR A OH 1 ATOM 2366 N N . ASN A 1 310 ? 72.830 6.989 61.460 1.00 11.61 ? 500 ASN A N 1 ATOM 2367 C CA . ASN A 1 310 ? 73.897 6.595 60.547 1.00 11.83 ? 500 ASN A CA 1 ATOM 2368 C C . ASN A 1 310 ? 75.182 7.406 60.660 1.00 12.40 ? 500 ASN A C 1 ATOM 2369 O O . ASN A 1 310 ? 75.758 7.804 59.654 1.00 13.76 ? 500 ASN A O 1 ATOM 2370 C CB . ASN A 1 310 ? 73.407 6.637 59.100 1.00 6.96 ? 500 ASN A CB 1 ATOM 2371 C CG . ASN A 1 310 ? 72.285 5.659 58.842 1.00 15.61 ? 500 ASN A CG 1 ATOM 2372 O OD1 . ASN A 1 310 ? 72.304 4.529 59.332 1.00 15.09 ? 500 ASN A OD1 1 ATOM 2373 N ND2 . ASN A 1 310 ? 71.302 6.083 58.060 1.00 21.86 ? 500 ASN A ND2 1 ATOM 2374 N N . GLY A 1 311 ? 75.627 7.647 61.888 1.00 14.07 ? 501 GLY A N 1 ATOM 2375 C CA . GLY A 1 311 ? 76.864 8.374 62.094 1.00 9.82 ? 501 GLY A CA 1 ATOM 2376 C C . GLY A 1 311 ? 76.756 9.879 62.163 1.00 11.12 ? 501 GLY A C 1 ATOM 2377 O O . GLY A 1 311 ? 77.776 10.566 62.227 1.00 15.58 ? 501 GLY A O 1 ATOM 2378 N N . ASN A 1 312 ? 75.535 10.402 62.152 1.00 15.64 ? 502 ASN A N 1 ATOM 2379 C CA . ASN A 1 312 ? 75.342 11.847 62.222 1.00 17.91 ? 502 ASN A CA 1 ATOM 2380 C C . ASN A 1 312 ? 74.275 12.253 63.225 1.00 18.10 ? 502 ASN A C 1 ATOM 2381 O O . ASN A 1 312 ? 73.552 11.412 63.757 1.00 20.02 ? 502 ASN A O 1 ATOM 2382 C CB . ASN A 1 312 ? 74.989 12.399 60.841 1.00 25.49 ? 502 ASN A CB 1 ATOM 2383 C CG . ASN A 1 312 ? 76.176 12.399 59.901 1.00 34.27 ? 502 ASN A CG 1 ATOM 2384 O OD1 . ASN A 1 312 ? 77.183 13.062 60.158 1.00 37.89 ? 502 ASN A OD1 1 ATOM 2385 N ND2 . ASN A 1 312 ? 76.068 11.649 58.805 1.00 35.58 ? 502 ASN A ND2 1 ATOM 2386 N N . CYS A 1 313 ? 74.183 13.551 63.484 1.00 20.65 ? 503 CYS A N 1 ATOM 2387 C CA . CYS A 1 313 ? 73.203 14.060 64.429 1.00 21.21 ? 503 CYS A CA 1 ATOM 2388 C C . CYS A 1 313 ? 72.392 15.188 63.804 1.00 23.70 ? 503 CYS A C 1 ATOM 2389 O O . CYS A 1 313 ? 72.493 16.343 64.214 1.00 30.69 ? 503 CYS A O 1 ATOM 2390 C CB . CYS A 1 313 ? 73.905 14.563 65.685 1.00 18.19 ? 503 CYS A CB 1 ATOM 2391 S SG . CYS A 1 313 ? 72.747 14.950 67.025 1.00 26.60 ? 503 CYS A SG 1 ATOM 2392 N N . PRO A 1 314 ? 71.561 14.860 62.803 1.00 19.85 ? 504 PRO A N 1 ATOM 2393 C CA . PRO A 1 314 ? 70.734 15.856 62.122 1.00 14.80 ? 504 PRO A CA 1 ATOM 2394 C C . PRO A 1 314 ? 69.738 16.585 63.017 1.00 16.51 ? 504 PRO A C 1 ATOM 2395 O O . PRO A 1 314 ? 68.937 15.963 63.711 1.00 19.65 ? 504 PRO A O 1 ATOM 2396 C CB . PRO A 1 314 ? 70.045 15.039 61.031 1.00 15.97 ? 504 PRO A CB 1 ATOM 2397 C CG . PRO A 1 314 ? 69.906 13.686 61.665 1.00 18.50 ? 504 PRO A CG 1 ATOM 2398 C CD . PRO A 1 314 ? 71.264 13.504 62.306 1.00 18.66 ? 504 PRO A CD 1 ATOM 2399 N N . ILE A 1 315 ? 69.796 17.911 62.996 1.00 18.98 ? 505 ILE A N 1 ATOM 2400 C CA . ILE A 1 315 ? 68.880 18.732 63.780 1.00 20.50 ? 505 ILE A CA 1 ATOM 2401 C C . ILE A 1 315 ? 68.447 19.938 62.949 1.00 19.44 ? 505 ILE A C 1 ATOM 2402 O O . ILE A 1 315 ? 69.195 20.410 62.089 1.00 23.82 ? 505 ILE A O 1 ATOM 2403 C CB . ILE A 1 315 ? 69.527 19.234 65.101 1.00 22.93 ? 505 ILE A CB 1 ATOM 2404 C CG1 . ILE A 1 315 ? 70.702 20.165 64.801 1.00 21.55 ? 505 ILE A CG1 1 ATOM 2405 C CG2 . ILE A 1 315 ? 69.991 18.051 65.933 1.00 26.54 ? 505 ILE A CG2 1 ATOM 2406 C CD1 . ILE A 1 315 ? 71.284 20.817 66.030 1.00 13.48 ? 505 ILE A CD1 1 ATOM 2407 N N . MET A 1 316 ? 67.240 20.429 63.208 1.00 12.83 ? 506 MET A N 1 ATOM 2408 C CA . MET A 1 316 ? 66.703 21.575 62.485 1.00 14.09 ? 506 MET A CA 1 ATOM 2409 C C . MET A 1 316 ? 67.715 22.720 62.365 1.00 17.52 ? 506 MET A C 1 ATOM 2410 O O . MET A 1 316 ? 68.043 23.160 61.262 1.00 20.16 ? 506 MET A O 1 ATOM 2411 C CB . MET A 1 316 ? 65.436 22.086 63.184 1.00 18.15 ? 506 MET A CB 1 ATOM 2412 C CG . MET A 1 316 ? 64.322 21.048 63.318 1.00 19.92 ? 506 MET A CG 1 ATOM 2413 S SD . MET A 1 316 ? 63.542 20.615 61.749 1.00 27.36 ? 506 MET A SD 1 ATOM 2414 C CE . MET A 1 316 ? 61.896 20.189 62.280 1.00 25.12 ? 506 MET A CE 1 ATOM 2415 N N . TYR A 1 317 ? 68.214 23.191 63.503 1.00 16.38 ? 507 TYR A N 1 ATOM 2416 C CA . TYR A 1 317 ? 69.164 24.297 63.524 1.00 17.08 ? 507 TYR A CA 1 ATOM 2417 C C . TYR A 1 317 ? 70.349 24.161 62.561 1.00 18.65 ? 507 TYR A C 1 ATOM 2418 O O . TYR A 1 317 ? 70.602 25.062 61.762 1.00 14.90 ? 507 TYR A O 1 ATOM 2419 C CB . TYR A 1 317 ? 69.676 24.522 64.949 1.00 17.21 ? 507 TYR A CB 1 ATOM 2420 C CG . TYR A 1 317 ? 70.670 25.653 65.050 1.00 29.07 ? 507 TYR A CG 1 ATOM 2421 C CD1 . TYR A 1 317 ? 70.362 26.920 64.552 1.00 27.63 ? 507 TYR A CD1 1 ATOM 2422 C CD2 . TYR A 1 317 ? 71.921 25.462 65.640 1.00 28.79 ? 507 TYR A CD2 1 ATOM 2423 C CE1 . TYR A 1 317 ? 71.270 27.967 64.638 1.00 27.63 ? 507 TYR A CE1 1 ATOM 2424 C CE2 . TYR A 1 317 ? 72.837 26.505 65.730 1.00 25.99 ? 507 TYR A CE2 1 ATOM 2425 C CZ . TYR A 1 317 ? 72.504 27.754 65.228 1.00 27.10 ? 507 TYR A CZ 1 ATOM 2426 O OH . TYR A 1 317 ? 73.398 28.798 65.319 1.00 36.40 ? 507 TYR A OH 1 ATOM 2427 N N . HIS A 1 318 ? 71.081 23.052 62.632 1.00 20.78 ? 508 HIS A N 1 ATOM 2428 C CA . HIS A 1 318 ? 72.220 22.872 61.738 1.00 23.91 ? 508 HIS A CA 1 ATOM 2429 C C . HIS A 1 318 ? 71.771 22.790 60.287 1.00 23.95 ? 508 HIS A C 1 ATOM 2430 O O . HIS A 1 318 ? 72.437 23.327 59.397 1.00 18.32 ? 508 HIS A O 1 ATOM 2431 C CB . HIS A 1 318 ? 73.021 21.614 62.095 1.00 23.81 ? 508 HIS A CB 1 ATOM 2432 C CG . HIS A 1 318 ? 73.780 21.725 63.381 1.00 25.36 ? 508 HIS A CG 1 ATOM 2433 N ND1 . HIS A 1 318 ? 74.245 22.928 63.868 1.00 29.40 ? 508 HIS A ND1 1 ATOM 2434 C CD2 . HIS A 1 318 ? 74.177 20.782 64.268 1.00 25.92 ? 508 HIS A CD2 1 ATOM 2435 C CE1 . HIS A 1 318 ? 74.893 22.722 65.000 1.00 26.12 ? 508 HIS A CE1 1 ATOM 2436 N NE2 . HIS A 1 318 ? 74.867 21.428 65.265 1.00 24.68 ? 508 HIS A NE2 1 ATOM 2437 N N . GLN A 1 319 ? 70.643 22.120 60.047 1.00 19.73 ? 509 GLN A N 1 ATOM 2438 C CA . GLN A 1 319 ? 70.126 21.988 58.687 1.00 18.22 ? 509 GLN A CA 1 ATOM 2439 C C . GLN A 1 319 ? 69.787 23.349 58.076 1.00 18.05 ? 509 GLN A C 1 ATOM 2440 O O . GLN A 1 319 ? 69.956 23.540 56.870 1.00 17.20 ? 509 GLN A O 1 ATOM 2441 C CB . GLN A 1 319 ? 68.906 21.065 58.656 1.00 13.96 ? 509 GLN A CB 1 ATOM 2442 C CG . GLN A 1 319 ? 69.243 19.602 58.920 1.00 13.17 ? 509 GLN A CG 1 ATOM 2443 C CD . GLN A 1 319 ? 68.022 18.702 58.897 1.00 12.44 ? 509 GLN A CD 1 ATOM 2444 O OE1 . GLN A 1 319 ? 67.414 18.479 57.847 1.00 12.38 ? 509 GLN A OE1 1 ATOM 2445 N NE2 . GLN A 1 319 ? 67.652 18.185 60.061 1.00 7.99 ? 509 GLN A NE2 1 ATOM 2446 N N . CYS A 1 320 ? 69.316 24.290 58.897 1.00 13.43 ? 510 CYS A N 1 ATOM 2447 C CA . CYS A 1 320 ? 69.006 25.634 58.404 1.00 16.19 ? 510 CYS A CA 1 ATOM 2448 C C . CYS A 1 320 ? 70.310 26.352 58.060 1.00 20.62 ? 510 CYS A C 1 ATOM 2449 O O . CYS A 1 320 ? 70.419 26.998 57.018 1.00 22.92 ? 510 CYS A O 1 ATOM 2450 C CB . CYS A 1 320 ? 68.247 26.453 59.451 1.00 9.10 ? 510 CYS A CB 1 ATOM 2451 S SG . CYS A 1 320 ? 66.477 26.057 59.613 1.00 18.82 ? 510 CYS A SG 1 ATOM 2452 N N . TYR A 1 321 ? 71.298 26.236 58.942 1.00 22.55 ? 511 TYR A N 1 ATOM 2453 C CA . TYR A 1 321 ? 72.595 26.863 58.719 1.00 20.90 ? 511 TYR A CA 1 ATOM 2454 C C . TYR A 1 321 ? 73.220 26.381 57.413 1.00 21.25 ? 511 TYR A C 1 ATOM 2455 O O . TYR A 1 321 ? 73.757 27.181 56.647 1.00 20.62 ? 511 TYR A O 1 ATOM 2456 C CB . TYR A 1 321 ? 73.548 26.554 59.875 1.00 24.22 ? 511 TYR A CB 1 ATOM 2457 C CG . TYR A 1 321 ? 75.001 26.830 59.549 1.00 27.88 ? 511 TYR A CG 1 ATOM 2458 C CD1 . TYR A 1 321 ? 75.459 28.133 59.359 1.00 28.98 ? 511 TYR A CD1 1 ATOM 2459 C CD2 . TYR A 1 321 ? 75.910 25.784 59.394 1.00 27.83 ? 511 TYR A CD2 1 ATOM 2460 C CE1 . TYR A 1 321 ? 76.784 28.389 59.021 1.00 27.91 ? 511 TYR A CE1 1 ATOM 2461 C CE2 . TYR A 1 321 ? 77.237 26.027 59.055 1.00 29.30 ? 511 TYR A CE2 1 ATOM 2462 C CZ . TYR A 1 321 ? 77.668 27.331 58.869 1.00 30.70 ? 511 TYR A CZ 1 ATOM 2463 O OH . TYR A 1 321 ? 78.979 27.574 58.526 1.00 33.80 ? 511 TYR A OH 1 ATOM 2464 N N . ASP A 1 322 ? 73.157 25.075 57.167 1.00 21.10 ? 512 ASP A N 1 ATOM 2465 C CA . ASP A 1 322 ? 73.729 24.510 55.949 1.00 26.82 ? 512 ASP A CA 1 ATOM 2466 C C . ASP A 1 322 ? 73.089 25.083 54.688 1.00 27.36 ? 512 ASP A C 1 ATOM 2467 O O . ASP A 1 322 ? 73.672 25.011 53.608 1.00 30.26 ? 512 ASP A O 1 ATOM 2468 C CB . ASP A 1 322 ? 73.583 22.984 55.933 1.00 31.52 ? 512 ASP A CB 1 ATOM 2469 C CG . ASP A 1 322 ? 74.397 22.304 57.020 1.00 41.83 ? 512 ASP A CG 1 ATOM 2470 O OD1 . ASP A 1 322 ? 75.608 22.599 57.131 1.00 40.72 ? 512 ASP A OD1 1 ATOM 2471 O OD2 . ASP A 1 322 ? 73.828 21.470 57.758 1.00 45.11 ? 512 ASP A OD2 1 ATOM 2472 N N . LEU A 1 323 ? 71.894 25.654 54.827 1.00 23.09 ? 513 LEU A N 1 ATOM 2473 C CA . LEU A 1 323 ? 71.181 26.221 53.686 1.00 18.09 ? 513 LEU A CA 1 ATOM 2474 C C . LEU A 1 323 ? 71.293 27.729 53.530 1.00 17.93 ? 513 LEU A C 1 ATOM 2475 O O . LEU A 1 323 ? 71.510 28.225 52.425 1.00 21.28 ? 513 LEU A O 1 ATOM 2476 C CB . LEU A 1 323 ? 69.695 25.861 53.752 1.00 21.22 ? 513 LEU A CB 1 ATOM 2477 C CG . LEU A 1 323 ? 69.262 24.466 53.305 1.00 20.00 ? 513 LEU A CG 1 ATOM 2478 C CD1 . LEU A 1 323 ? 67.768 24.316 53.515 1.00 20.26 ? 513 LEU A CD1 1 ATOM 2479 C CD2 . LEU A 1 323 ? 69.616 24.264 51.842 1.00 15.88 ? 513 LEU A CD2 1 ATOM 2480 N N . PHE A 1 324 ? 71.140 28.460 54.629 1.00 16.53 ? 514 PHE A N 1 ATOM 2481 C CA . PHE A 1 324 ? 71.180 29.917 54.578 1.00 14.34 ? 514 PHE A CA 1 ATOM 2482 C C . PHE A 1 324 ? 72.329 30.564 55.342 1.00 10.22 ? 514 PHE A C 1 ATOM 2483 O O . PHE A 1 324 ? 72.409 31.787 55.425 1.00 9.78 ? 514 PHE A O 1 ATOM 2484 C CB . PHE A 1 324 ? 69.855 30.466 55.095 1.00 8.77 ? 514 PHE A CB 1 ATOM 2485 C CG . PHE A 1 324 ? 68.659 29.786 54.511 1.00 14.93 ? 514 PHE A CG 1 ATOM 2486 C CD1 . PHE A 1 324 ? 67.619 29.348 55.335 1.00 19.42 ? 514 PHE A CD1 1 ATOM 2487 C CD2 . PHE A 1 324 ? 68.569 29.566 53.140 1.00 13.28 ? 514 PHE A CD2 1 ATOM 2488 C CE1 . PHE A 1 324 ? 66.503 28.696 54.803 1.00 16.21 ? 514 PHE A CE1 1 ATOM 2489 C CE2 . PHE A 1 324 ? 67.458 28.916 52.592 1.00 23.27 ? 514 PHE A CE2 1 ATOM 2490 C CZ . PHE A 1 324 ? 66.421 28.479 53.429 1.00 20.13 ? 514 PHE A CZ 1 ATOM 2491 N N . GLY A 1 325 ? 73.209 29.751 55.908 1.00 7.54 ? 515 GLY A N 1 ATOM 2492 C CA . GLY A 1 325 ? 74.328 30.301 56.644 1.00 10.37 ? 515 GLY A CA 1 ATOM 2493 C C . GLY A 1 325 ? 74.027 30.581 58.103 1.00 19.15 ? 515 GLY A C 1 ATOM 2494 O O . GLY A 1 325 ? 72.998 30.162 58.637 1.00 11.98 ? 515 GLY A O 1 ATOM 2495 N N . ALA A 1 326 ? 74.938 31.310 58.744 1.00 26.91 ? 516 ALA A N 1 ATOM 2496 C CA . ALA A 1 326 ? 74.824 31.650 60.158 1.00 26.86 ? 516 ALA A CA 1 ATOM 2497 C C . ALA A 1 326 ? 73.678 32.602 60.486 1.00 28.40 ? 516 ALA A C 1 ATOM 2498 O O . ALA A 1 326 ? 73.072 33.198 59.598 1.00 26.24 ? 516 ALA A O 1 ATOM 2499 C CB . ALA A 1 326 ? 76.144 32.234 60.652 1.00 18.30 ? 516 ALA A CB 1 ATOM 2500 N N . ASP A 1 327 ? 73.401 32.727 61.782 1.00 32.56 ? 517 ASP A N 1 ATOM 2501 C CA . ASP A 1 327 ? 72.347 33.588 62.305 1.00 37.80 ? 517 ASP A CA 1 ATOM 2502 C C . ASP A 1 327 ? 70.953 33.260 61.769 1.00 41.08 ? 517 ASP A C 1 ATOM 2503 O O . ASP A 1 327 ? 70.040 34.082 61.850 1.00 42.34 ? 517 ASP A O 1 ATOM 2504 C CB . ASP A 1 327 ? 72.681 35.062 62.042 1.00 45.40 ? 517 ASP A CB 1 ATOM 2505 C CG . ASP A 1 327 ? 73.921 35.531 62.801 1.00 51.25 ? 517 ASP A CG 1 ATOM 2506 O OD1 . ASP A 1 327 ? 74.026 35.255 64.018 1.00 52.84 ? 517 ASP A OD1 1 ATOM 2507 O OD2 . ASP A 1 327 ? 74.787 36.189 62.184 1.00 51.91 ? 517 ASP A OD2 1 ATOM 2508 N N . VAL A 1 328 ? 70.796 32.058 61.223 1.00 42.68 ? 518 VAL A N 1 ATOM 2509 C CA . VAL A 1 328 ? 69.508 31.605 60.698 1.00 43.51 ? 518 VAL A CA 1 ATOM 2510 C C . VAL A 1 328 ? 69.033 30.440 61.568 1.00 43.73 ? 518 VAL A C 1 ATOM 2511 O O . VAL A 1 328 ? 69.803 29.519 61.848 1.00 45.15 ? 518 VAL A O 1 ATOM 2512 C CB . VAL A 1 328 ? 69.628 31.134 59.231 1.00 43.17 ? 518 VAL A CB 1 ATOM 2513 C CG1 . VAL A 1 328 ? 68.346 30.441 58.801 1.00 44.15 ? 518 VAL A CG1 1 ATOM 2514 C CG2 . VAL A 1 328 ? 69.907 32.324 58.325 1.00 37.56 ? 518 VAL A CG2 1 ATOM 2515 N N . TYR A 1 329 ? 67.771 30.478 61.989 1.00 40.15 ? 519 TYR A N 1 ATOM 2516 C CA . TYR A 1 329 ? 67.236 29.431 62.857 1.00 36.21 ? 519 TYR A CA 1 ATOM 2517 C C . TYR A 1 329 ? 65.968 28.781 62.329 1.00 34.23 ? 519 TYR A C 1 ATOM 2518 O O . TYR A 1 329 ? 65.430 29.183 61.301 1.00 33.15 ? 519 TYR A O 1 ATOM 2519 C CB . TYR A 1 329 ? 66.968 30.005 64.250 1.00 31.49 ? 519 TYR A CB 1 ATOM 2520 C CG . TYR A 1 329 ? 68.005 31.015 64.682 1.00 39.06 ? 519 TYR A CG 1 ATOM 2521 C CD1 . TYR A 1 329 ? 67.894 32.356 64.310 1.00 41.64 ? 519 TYR A CD1 1 ATOM 2522 C CD2 . TYR A 1 329 ? 69.125 30.625 65.416 1.00 34.57 ? 519 TYR A CD2 1 ATOM 2523 C CE1 . TYR A 1 329 ? 68.875 33.284 64.655 1.00 39.00 ? 519 TYR A CE1 1 ATOM 2524 C CE2 . TYR A 1 329 ? 70.111 31.545 65.766 1.00 35.94 ? 519 TYR A CE2 1 ATOM 2525 C CZ . TYR A 1 329 ? 69.981 32.872 65.381 1.00 38.58 ? 519 TYR A CZ 1 ATOM 2526 O OH . TYR A 1 329 ? 70.960 33.783 65.708 1.00 36.29 ? 519 TYR A OH 1 ATOM 2527 N N . GLU A 1 330 ? 65.499 27.767 63.049 1.00 33.41 ? 520 GLU A N 1 ATOM 2528 C CA . GLU A 1 330 ? 64.287 27.052 62.678 1.00 32.20 ? 520 GLU A CA 1 ATOM 2529 C C . GLU A 1 330 ? 63.069 27.960 62.813 1.00 28.14 ? 520 GLU A C 1 ATOM 2530 O O . GLU A 1 330 ? 62.959 28.731 63.766 1.00 25.64 ? 520 GLU A O 1 ATOM 2531 C CB . GLU A 1 330 ? 64.119 25.812 63.563 1.00 36.76 ? 520 GLU A CB 1 ATOM 2532 C CG . GLU A 1 330 ? 62.723 25.200 63.531 1.00 41.66 ? 520 GLU A CG 1 ATOM 2533 C CD . GLU A 1 330 ? 62.660 23.839 64.206 1.00 46.05 ? 520 GLU A CD 1 ATOM 2534 O OE1 . GLU A 1 330 ? 63.213 23.693 65.320 1.00 41.54 ? 520 GLU A OE1 1 ATOM 2535 O OE2 . GLU A 1 330 ? 62.050 22.917 63.621 1.00 44.43 ? 520 GLU A OE2 1 ATOM 2536 N N . ALA A 1 331 ? 62.158 27.860 61.851 1.00 24.39 ? 521 ALA A N 1 ATOM 2537 C CA . ALA A 1 331 ? 60.949 28.669 61.845 1.00 24.40 ? 521 ALA A CA 1 ATOM 2538 C C . ALA A 1 331 ? 59.912 28.155 62.838 1.00 28.48 ? 521 ALA A C 1 ATOM 2539 O O . ALA A 1 331 ? 60.024 27.037 63.347 1.00 26.99 ? 521 ALA A O 1 ATOM 2540 C CB . ALA A 1 331 ? 60.360 28.692 60.451 1.00 21.79 ? 521 ALA A CB 1 ATOM 2541 N N . GLU A 1 332 ? 58.904 28.984 63.106 1.00 32.66 ? 522 GLU A N 1 ATOM 2542 C CA . GLU A 1 332 ? 57.825 28.638 64.030 1.00 32.81 ? 522 GLU A CA 1 ATOM 2543 C C . GLU A 1 332 ? 57.021 27.462 63.485 1.00 31.31 ? 522 GLU A C 1 ATOM 2544 O O . GLU A 1 332 ? 56.988 27.230 62.276 1.00 30.37 ? 522 GLU A O 1 ATOM 2545 C CB . GLU A 1 332 ? 56.893 29.839 64.231 1.00 35.04 ? 522 GLU A CB 1 ATOM 2546 C CG . GLU A 1 332 ? 57.542 31.043 64.900 1.00 46.20 ? 522 GLU A CG 1 ATOM 2547 C CD . GLU A 1 332 ? 57.837 30.815 66.374 1.00 54.26 ? 522 GLU A CD 1 ATOM 2548 O OE1 . GLU A 1 332 ? 56.878 30.632 67.157 1.00 55.59 ? 522 GLU A OE1 1 ATOM 2549 O OE2 . GLU A 1 332 ? 59.030 30.821 66.750 1.00 58.07 ? 522 GLU A OE2 1 ATOM 2550 N N . ASP A 1 333 ? 56.371 26.724 64.380 1.00 31.11 ? 523 ASP A N 1 ATOM 2551 C CA . ASP A 1 333 ? 55.567 25.573 63.985 1.00 29.51 ? 523 ASP A CA 1 ATOM 2552 C C . ASP A 1 333 ? 54.610 25.903 62.843 1.00 31.09 ? 523 ASP A C 1 ATOM 2553 O O . ASP A 1 333 ? 54.525 25.162 61.863 1.00 34.32 ? 523 ASP A O 1 ATOM 2554 C CB . ASP A 1 333 ? 54.770 25.049 65.181 1.00 27.43 ? 523 ASP A CB 1 ATOM 2555 C CG . ASP A 1 333 ? 55.642 24.360 66.207 1.00 35.27 ? 523 ASP A CG 1 ATOM 2556 O OD1 . ASP A 1 333 ? 55.110 23.949 67.260 1.00 38.64 ? 523 ASP A OD1 1 ATOM 2557 O OD2 . ASP A 1 333 ? 56.859 24.222 65.961 1.00 38.43 ? 523 ASP A OD2 1 ATOM 2558 N N . SER A 1 334 ? 53.893 27.015 62.971 1.00 30.75 ? 524 SER A N 1 ATOM 2559 C CA . SER A 1 334 ? 52.935 27.429 61.952 1.00 30.18 ? 524 SER A CA 1 ATOM 2560 C C . SER A 1 334 ? 53.497 27.349 60.532 1.00 26.05 ? 524 SER A C 1 ATOM 2561 O O . SER A 1 334 ? 52.803 26.930 59.609 1.00 27.26 ? 524 SER A O 1 ATOM 2562 C CB . SER A 1 334 ? 52.448 28.850 62.238 1.00 31.89 ? 524 SER A CB 1 ATOM 2563 O OG . SER A 1 334 ? 53.530 29.761 62.283 1.00 43.78 ? 524 SER A OG 1 ATOM 2564 N N . CYS A 1 335 ? 54.751 27.748 60.355 1.00 25.41 ? 525 CYS A N 1 ATOM 2565 C CA . CYS A 1 335 ? 55.373 27.705 59.036 1.00 24.77 ? 525 CYS A CA 1 ATOM 2566 C C . CYS A 1 335 ? 55.362 26.299 58.437 1.00 22.62 ? 525 CYS A C 1 ATOM 2567 O O . CYS A 1 335 ? 55.177 26.129 57.232 1.00 22.97 ? 525 CYS A O 1 ATOM 2568 C CB . CYS A 1 335 ? 56.824 28.190 59.099 1.00 25.56 ? 525 CYS A CB 1 ATOM 2569 S SG . CYS A 1 335 ? 57.110 29.990 59.175 1.00 26.57 ? 525 CYS A SG 1 ATOM 2570 N N . PHE A 1 336 ? 55.562 25.294 59.281 1.00 19.55 ? 526 PHE A N 1 ATOM 2571 C CA . PHE A 1 336 ? 55.606 23.912 58.819 1.00 20.62 ? 526 PHE A CA 1 ATOM 2572 C C . PHE A 1 336 ? 54.277 23.350 58.316 1.00 23.16 ? 526 PHE A C 1 ATOM 2573 O O . PHE A 1 336 ? 54.235 22.261 57.735 1.00 23.93 ? 526 PHE A O 1 ATOM 2574 C CB . PHE A 1 336 ? 56.184 23.011 59.920 1.00 12.43 ? 526 PHE A CB 1 ATOM 2575 C CG . PHE A 1 336 ? 57.672 23.142 60.087 1.00 13.07 ? 526 PHE A CG 1 ATOM 2576 C CD1 . PHE A 1 336 ? 58.223 24.254 60.721 1.00 12.83 ? 526 PHE A CD1 1 ATOM 2577 C CD2 . PHE A 1 336 ? 58.527 22.174 59.569 1.00 8.99 ? 526 PHE A CD2 1 ATOM 2578 C CE1 . PHE A 1 336 ? 59.607 24.399 60.833 1.00 16.19 ? 526 PHE A CE1 1 ATOM 2579 C CE2 . PHE A 1 336 ? 59.911 22.308 59.675 1.00 13.33 ? 526 PHE A CE2 1 ATOM 2580 C CZ . PHE A 1 336 ? 60.452 23.421 60.307 1.00 17.33 ? 526 PHE A CZ 1 ATOM 2581 N N . GLU A 1 337 ? 53.194 24.090 58.526 1.00 24.91 ? 527 GLU A N 1 ATOM 2582 C CA . GLU A 1 337 ? 51.882 23.639 58.074 1.00 26.38 ? 527 GLU A CA 1 ATOM 2583 C C . GLU A 1 337 ? 51.776 23.731 56.553 1.00 26.21 ? 527 GLU A C 1 ATOM 2584 O O . GLU A 1 337 ? 50.864 23.161 55.950 1.00 22.82 ? 527 GLU A O 1 ATOM 2585 C CB . GLU A 1 337 ? 50.785 24.470 58.742 1.00 27.68 ? 527 GLU A CB 1 ATOM 2586 C CG . GLU A 1 337 ? 50.788 24.346 60.261 1.00 34.55 ? 527 GLU A CG 1 ATOM 2587 C CD . GLU A 1 337 ? 49.715 25.185 60.929 1.00 37.94 ? 527 GLU A CD 1 ATOM 2588 O OE1 . GLU A 1 337 ? 49.656 25.180 62.177 1.00 40.10 ? 527 GLU A OE1 1 ATOM 2589 O OE2 . GLU A 1 337 ? 48.934 25.846 60.211 1.00 38.27 ? 527 GLU A OE2 1 ATOM 2590 N N . ARG A 1 338 ? 52.719 24.447 55.940 1.00 24.37 ? 528 ARG A N 1 ATOM 2591 C CA . ARG A 1 338 ? 52.759 24.603 54.488 1.00 21.54 ? 528 ARG A CA 1 ATOM 2592 C C . ARG A 1 338 ? 52.973 23.250 53.816 1.00 21.04 ? 528 ARG A C 1 ATOM 2593 O O . ARG A 1 338 ? 52.644 23.066 52.645 1.00 22.42 ? 528 ARG A O 1 ATOM 2594 C CB . ARG A 1 338 ? 53.901 25.535 54.076 1.00 21.93 ? 528 ARG A CB 1 ATOM 2595 C CG . ARG A 1 338 ? 53.633 27.027 54.225 1.00 30.91 ? 528 ARG A CG 1 ATOM 2596 C CD . ARG A 1 338 ? 54.873 27.813 53.798 1.00 36.72 ? 528 ARG A CD 1 ATOM 2597 N NE . ARG A 1 338 ? 54.678 29.262 53.733 1.00 37.36 ? 528 ARG A NE 1 ATOM 2598 C CZ . ARG A 1 338 ? 54.277 30.021 54.750 1.00 37.95 ? 528 ARG A CZ 1 ATOM 2599 N NH1 . ARG A 1 338 ? 54.013 29.478 55.931 1.00 40.94 ? 528 ARG A NH1 1 ATOM 2600 N NH2 . ARG A 1 338 ? 54.165 31.331 54.591 1.00 28.71 ? 528 ARG A NH2 1 ATOM 2601 N N . ASN A 1 339 ? 53.533 22.306 54.563 1.00 15.85 ? 529 ASN A N 1 ATOM 2602 C CA . ASN A 1 339 ? 53.800 20.978 54.032 1.00 14.10 ? 529 ASN A CA 1 ATOM 2603 C C . ASN A 1 339 ? 52.535 20.137 53.844 1.00 13.75 ? 529 ASN A C 1 ATOM 2604 O O . ASN A 1 339 ? 52.594 19.018 53.340 1.00 13.82 ? 529 ASN A O 1 ATOM 2605 C CB . ASN A 1 339 ? 54.806 20.256 54.937 1.00 13.86 ? 529 ASN A CB 1 ATOM 2606 C CG . ASN A 1 339 ? 56.211 20.845 54.834 1.00 18.26 ? 529 ASN A CG 1 ATOM 2607 O OD1 . ASN A 1 339 ? 57.082 20.566 55.661 1.00 21.38 ? 529 ASN A OD1 1 ATOM 2608 N ND2 . ASN A 1 339 ? 56.436 21.658 53.809 1.00 10.49 ? 529 ASN A ND2 1 ATOM 2609 N N . GLN A 1 340 ? 51.390 20.676 54.245 1.00 15.56 ? 530 GLN A N 1 ATOM 2610 C CA . GLN A 1 340 ? 50.129 19.962 54.076 1.00 19.24 ? 530 GLN A CA 1 ATOM 2611 C C . GLN A 1 340 ? 49.547 20.244 52.690 1.00 20.48 ? 530 GLN A C 1 ATOM 2612 O O . GLN A 1 340 ? 48.733 19.474 52.186 1.00 24.44 ? 530 GLN A O 1 ATOM 2613 C CB . GLN A 1 340 ? 49.119 20.384 55.144 1.00 14.45 ? 530 GLN A CB 1 ATOM 2614 C CG . GLN A 1 340 ? 49.560 20.086 56.559 1.00 18.49 ? 530 GLN A CG 1 ATOM 2615 C CD . GLN A 1 340 ? 48.477 20.368 57.580 1.00 24.34 ? 530 GLN A CD 1 ATOM 2616 O OE1 . GLN A 1 340 ? 47.412 19.748 57.561 1.00 25.83 ? 530 GLN A OE1 1 ATOM 2617 N NE2 . GLN A 1 340 ? 48.743 21.305 58.479 1.00 24.16 ? 530 GLN A NE2 1 ATOM 2618 N N . LYS A 1 341 ? 49.973 21.351 52.083 1.00 22.34 ? 531 LYS A N 1 ATOM 2619 C CA . LYS A 1 341 ? 49.500 21.750 50.757 1.00 22.81 ? 531 LYS A CA 1 ATOM 2620 C C . LYS A 1 341 ? 49.692 20.639 49.729 1.00 25.47 ? 531 LYS A C 1 ATOM 2621 O O . LYS A 1 341 ? 48.834 20.406 48.877 1.00 25.33 ? 531 LYS A O 1 ATOM 2622 C CB . LYS A 1 341 ? 50.252 22.990 50.261 1.00 19.46 ? 531 LYS A CB 1 ATOM 2623 C CG . LYS A 1 341 ? 50.134 24.236 51.119 1.00 18.29 ? 531 LYS A CG 1 ATOM 2624 C CD . LYS A 1 341 ? 50.996 25.350 50.523 1.00 17.84 ? 531 LYS A CD 1 ATOM 2625 C CE . LYS A 1 341 ? 50.946 26.621 51.346 1.00 18.67 ? 531 LYS A CE 1 ATOM 2626 N NZ . LYS A 1 341 ? 49.569 27.184 51.399 1.00 24.59 ? 531 LYS A NZ 1 ATOM 2627 N N . GLY A 1 342 ? 50.829 19.960 49.805 1.00 25.35 ? 532 GLY A N 1 ATOM 2628 C CA . GLY A 1 342 ? 51.104 18.903 48.856 1.00 24.18 ? 532 GLY A CA 1 ATOM 2629 C C . GLY A 1 342 ? 51.434 19.496 47.501 1.00 26.18 ? 532 GLY A C 1 ATOM 2630 O O . GLY A 1 342 ? 51.271 18.833 46.476 1.00 26.71 ? 532 GLY A O 1 ATOM 2631 N N . ASN A 1 343 ? 51.892 20.747 47.490 1.00 25.92 ? 533 ASN A N 1 ATOM 2632 C CA . ASN A 1 343 ? 52.245 21.406 46.237 1.00 22.61 ? 533 ASN A CA 1 ATOM 2633 C C . ASN A 1 343 ? 53.672 21.073 45.813 1.00 19.62 ? 533 ASN A C 1 ATOM 2634 O O . ASN A 1 343 ? 54.229 20.056 46.224 1.00 20.08 ? 533 ASN A O 1 ATOM 2635 C CB . ASN A 1 343 ? 52.076 22.927 46.337 1.00 18.96 ? 533 ASN A CB 1 ATOM 2636 C CG . ASN A 1 343 ? 52.893 23.535 47.454 1.00 26.59 ? 533 ASN A CG 1 ATOM 2637 O OD1 . ASN A 1 343 ? 53.947 23.017 47.822 1.00 32.92 ? 533 ASN A OD1 1 ATOM 2638 N ND2 . ASN A 1 343 ? 52.419 24.654 47.989 1.00 23.91 ? 533 ASN A ND2 1 ATOM 2639 N N . TYR A 1 344 ? 54.267 21.939 45.001 1.00 18.54 ? 534 TYR A N 1 ATOM 2640 C CA . TYR A 1 344 ? 55.611 21.692 44.498 1.00 18.47 ? 534 TYR A CA 1 ATOM 2641 C C . TYR A 1 344 ? 56.735 21.727 45.527 1.00 17.30 ? 534 TYR A C 1 ATOM 2642 O O . TYR A 1 344 ? 57.827 21.230 45.254 1.00 16.53 ? 534 TYR A O 1 ATOM 2643 C CB . TYR A 1 344 ? 55.925 22.658 43.343 1.00 15.29 ? 534 TYR A CB 1 ATOM 2644 C CG . TYR A 1 344 ? 56.230 24.088 43.739 1.00 13.73 ? 534 TYR A CG 1 ATOM 2645 C CD1 . TYR A 1 344 ? 57.546 24.507 43.961 1.00 12.08 ? 534 TYR A CD1 1 ATOM 2646 C CD2 . TYR A 1 344 ? 55.210 25.033 43.856 1.00 13.62 ? 534 TYR A CD2 1 ATOM 2647 C CE1 . TYR A 1 344 ? 57.837 25.834 44.282 1.00 7.89 ? 534 TYR A CE1 1 ATOM 2648 C CE2 . TYR A 1 344 ? 55.487 26.364 44.178 1.00 10.33 ? 534 TYR A CE2 1 ATOM 2649 C CZ . TYR A 1 344 ? 56.802 26.758 44.387 1.00 16.08 ? 534 TYR A CZ 1 ATOM 2650 O OH . TYR A 1 344 ? 57.082 28.075 44.690 1.00 18.40 ? 534 TYR A OH 1 ATOM 2651 N N . TYR A 1 345 ? 56.486 22.292 46.706 1.00 11.27 ? 535 TYR A N 1 ATOM 2652 C CA . TYR A 1 345 ? 57.543 22.355 47.711 1.00 14.22 ? 535 TYR A CA 1 ATOM 2653 C C . TYR A 1 345 ? 57.132 21.879 49.108 1.00 14.63 ? 535 TYR A C 1 ATOM 2654 O O . TYR A 1 345 ? 57.967 21.396 49.878 1.00 12.41 ? 535 TYR A O 1 ATOM 2655 C CB . TYR A 1 345 ? 58.106 23.782 47.785 1.00 12.38 ? 535 TYR A CB 1 ATOM 2656 C CG . TYR A 1 345 ? 57.209 24.781 48.477 1.00 14.46 ? 535 TYR A CG 1 ATOM 2657 C CD1 . TYR A 1 345 ? 57.040 24.749 49.863 1.00 17.22 ? 535 TYR A CD1 1 ATOM 2658 C CD2 . TYR A 1 345 ? 56.517 25.753 47.751 1.00 13.35 ? 535 TYR A CD2 1 ATOM 2659 C CE1 . TYR A 1 345 ? 56.205 25.653 50.510 1.00 22.69 ? 535 TYR A CE1 1 ATOM 2660 C CE2 . TYR A 1 345 ? 55.676 26.667 48.392 1.00 13.17 ? 535 TYR A CE2 1 ATOM 2661 C CZ . TYR A 1 345 ? 55.526 26.607 49.771 1.00 16.10 ? 535 TYR A CZ 1 ATOM 2662 O OH . TYR A 1 345 ? 54.700 27.490 50.424 1.00 22.05 ? 535 TYR A OH 1 ATOM 2663 N N . GLY A 1 346 ? 55.851 22.017 49.433 1.00 10.10 ? 536 GLY A N 1 ATOM 2664 C CA . GLY A 1 346 ? 55.377 21.603 50.736 1.00 8.95 ? 536 GLY A CA 1 ATOM 2665 C C . GLY A 1 346 ? 54.740 20.229 50.740 1.00 18.11 ? 536 GLY A C 1 ATOM 2666 O O . GLY A 1 346 ? 53.515 20.102 50.711 1.00 23.20 ? 536 GLY A O 1 ATOM 2667 N N . TYR A 1 347 ? 55.573 19.196 50.769 1.00 20.91 ? 537 TYR A N 1 ATOM 2668 C CA . TYR A 1 347 ? 55.091 17.822 50.801 1.00 22.62 ? 537 TYR A CA 1 ATOM 2669 C C . TYR A 1 347 ? 55.916 17.041 51.809 1.00 20.99 ? 537 TYR A C 1 ATOM 2670 O O . TYR A 1 347 ? 56.846 17.586 52.395 1.00 26.44 ? 537 TYR A O 1 ATOM 2671 C CB . TYR A 1 347 ? 55.186 17.188 49.410 1.00 24.17 ? 537 TYR A CB 1 ATOM 2672 C CG . TYR A 1 347 ? 56.551 17.264 48.769 1.00 25.83 ? 537 TYR A CG 1 ATOM 2673 C CD1 . TYR A 1 347 ? 57.454 16.206 48.872 1.00 29.15 ? 537 TYR A CD1 1 ATOM 2674 C CD2 . TYR A 1 347 ? 56.935 18.390 48.041 1.00 26.00 ? 537 TYR A CD2 1 ATOM 2675 C CE1 . TYR A 1 347 ? 58.705 16.267 48.260 1.00 26.73 ? 537 TYR A CE1 1 ATOM 2676 C CE2 . TYR A 1 347 ? 58.182 18.461 47.430 1.00 25.53 ? 537 TYR A CE2 1 ATOM 2677 C CZ . TYR A 1 347 ? 59.060 17.399 47.542 1.00 26.49 ? 537 TYR A CZ 1 ATOM 2678 O OH . TYR A 1 347 ? 60.293 17.473 46.936 1.00 30.37 ? 537 TYR A OH 1 ATOM 2679 N N . CYS A 1 348 ? 55.578 15.774 52.020 1.00 21.76 ? 538 CYS A N 1 ATOM 2680 C CA . CYS A 1 348 ? 56.302 14.949 52.982 1.00 24.12 ? 538 CYS A CA 1 ATOM 2681 C C . CYS A 1 348 ? 57.188 13.884 52.354 1.00 24.99 ? 538 CYS A C 1 ATOM 2682 O O . CYS A 1 348 ? 58.250 13.560 52.881 1.00 26.14 ? 538 CYS A O 1 ATOM 2683 C CB . CYS A 1 348 ? 55.318 14.283 53.952 1.00 26.04 ? 538 CYS A CB 1 ATOM 2684 S SG . CYS A 1 348 ? 55.472 14.945 55.639 1.00 27.13 ? 538 CYS A SG 1 ATOM 2685 N N . ARG A 1 349 ? 56.752 13.348 51.223 1.00 26.29 ? 539 ARG A N 1 ATOM 2686 C CA . ARG A 1 349 ? 57.495 12.299 50.543 1.00 25.59 ? 539 ARG A CA 1 ATOM 2687 C C . ARG A 1 349 ? 56.962 12.145 49.130 1.00 27.53 ? 539 ARG A C 1 ATOM 2688 O O . ARG A 1 349 ? 55.979 12.791 48.759 1.00 25.88 ? 539 ARG A O 1 ATOM 2689 C CB . ARG A 1 349 ? 57.327 10.984 51.306 1.00 26.67 ? 539 ARG A CB 1 ATOM 2690 C CG . ARG A 1 349 ? 55.891 10.737 51.734 1.00 29.12 ? 539 ARG A CG 1 ATOM 2691 C CD . ARG A 1 349 ? 55.726 9.451 52.518 1.00 36.27 ? 539 ARG A CD 1 ATOM 2692 N NE . ARG A 1 349 ? 54.375 9.347 53.063 1.00 38.11 ? 539 ARG A NE 1 ATOM 2693 C CZ . ARG A 1 349 ? 53.912 10.089 54.066 1.00 38.21 ? 539 ARG A CZ 1 ATOM 2694 N NH1 . ARG A 1 349 ? 54.695 10.990 54.646 1.00 29.18 ? 539 ARG A NH1 1 ATOM 2695 N NH2 . ARG A 1 349 ? 52.657 9.943 54.478 1.00 40.11 ? 539 ARG A NH2 1 ATOM 2696 N N . LYS A 1 350 ? 57.610 11.287 48.347 1.00 25.80 ? 540 LYS A N 1 ATOM 2697 C CA . LYS A 1 350 ? 57.186 11.055 46.976 1.00 30.80 ? 540 LYS A CA 1 ATOM 2698 C C . LYS A 1 350 ? 56.827 9.597 46.684 1.00 36.92 ? 540 LYS A C 1 ATOM 2699 O O . LYS A 1 350 ? 57.563 8.677 47.041 1.00 38.11 ? 540 LYS A O 1 ATOM 2700 C CB . LYS A 1 350 ? 58.267 11.537 46.006 1.00 28.46 ? 540 LYS A CB 1 ATOM 2701 C CG . LYS A 1 350 ? 58.401 13.053 45.953 1.00 28.23 ? 540 LYS A CG 1 ATOM 2702 C CD . LYS A 1 350 ? 58.641 13.536 44.528 1.00 27.15 ? 540 LYS A CD 1 ATOM 2703 C CE . LYS A 1 350 ? 60.115 13.541 44.157 1.00 23.47 ? 540 LYS A CE 1 ATOM 2704 N NZ . LYS A 1 350 ? 60.823 14.690 44.787 1.00 22.97 ? 540 LYS A NZ 1 ATOM 2705 N N . GLU A 1 351 ? 55.679 9.403 46.036 1.00 42.11 ? 541 GLU A N 1 ATOM 2706 C CA . GLU A 1 351 ? 55.192 8.076 45.672 1.00 43.02 ? 541 GLU A CA 1 ATOM 2707 C C . GLU A 1 351 ? 55.234 7.915 44.156 1.00 44.61 ? 541 GLU A C 1 ATOM 2708 O O . GLU A 1 351 ? 54.442 8.526 43.436 1.00 40.96 ? 541 GLU A O 1 ATOM 2709 C CB . GLU A 1 351 ? 53.748 7.881 46.146 1.00 47.82 ? 541 GLU A CB 1 ATOM 2710 C CG . GLU A 1 351 ? 53.530 8.052 47.639 1.00 53.82 ? 541 GLU A CG 1 ATOM 2711 C CD . GLU A 1 351 ? 54.182 6.964 48.462 1.00 56.27 ? 541 GLU A CD 1 ATOM 2712 O OE1 . GLU A 1 351 ? 55.412 6.787 48.349 1.00 62.54 ? 541 GLU A OE1 1 ATOM 2713 O OE2 . GLU A 1 351 ? 53.461 6.288 49.225 1.00 56.26 ? 541 GLU A OE2 1 ATOM 2714 N N . ASN A 1 352 ? 56.160 7.089 43.680 1.00 45.76 ? 542 ASN A N 1 ATOM 2715 C CA . ASN A 1 352 ? 56.311 6.836 42.251 1.00 44.86 ? 542 ASN A CA 1 ATOM 2716 C C . ASN A 1 352 ? 56.370 8.114 41.423 1.00 42.71 ? 542 ASN A C 1 ATOM 2717 O O . ASN A 1 352 ? 56.146 8.086 40.213 1.00 43.50 ? 542 ASN A O 1 ATOM 2718 C CB . ASN A 1 352 ? 55.168 5.951 41.751 1.00 44.65 ? 542 ASN A CB 1 ATOM 2719 C CG . ASN A 1 352 ? 55.205 4.561 42.352 1.00 49.83 ? 542 ASN A CG 1 ATOM 2720 O OD1 . ASN A 1 352 ? 56.144 3.798 42.121 1.00 47.70 ? 542 ASN A OD1 1 ATOM 2721 N ND2 . ASN A 1 352 ? 54.183 4.225 43.133 1.00 52.11 ? 542 ASN A ND2 1 ATOM 2722 N N . GLY A 1 353 ? 56.670 9.233 42.075 1.00 40.26 ? 543 GLY A N 1 ATOM 2723 C CA . GLY A 1 353 ? 56.763 10.492 41.361 1.00 38.26 ? 543 GLY A CA 1 ATOM 2724 C C . GLY A 1 353 ? 55.778 11.548 41.814 1.00 35.49 ? 543 GLY A C 1 ATOM 2725 O O . GLY A 1 353 ? 55.914 12.719 41.457 1.00 36.39 ? 543 GLY A O 1 ATOM 2726 N N . ASN A 1 354 ? 54.784 11.140 42.595 1.00 32.90 ? 544 ASN A N 1 ATOM 2727 C CA . ASN A 1 354 ? 53.777 12.072 43.095 1.00 28.86 ? 544 ASN A CA 1 ATOM 2728 C C . ASN A 1 354 ? 54.201 12.600 44.461 1.00 24.92 ? 544 ASN A C 1 ATOM 2729 O O . ASN A 1 354 ? 54.714 11.850 45.292 1.00 22.73 ? 544 ASN A O 1 ATOM 2730 C CB . ASN A 1 354 ? 52.419 11.373 43.217 1.00 29.21 ? 544 ASN A CB 1 ATOM 2731 C CG . ASN A 1 354 ? 52.013 10.659 41.942 1.00 32.85 ? 544 ASN A CG 1 ATOM 2732 O OD1 . ASN A 1 354 ? 51.829 11.283 40.896 1.00 32.01 ? 544 ASN A OD1 1 ATOM 2733 N ND2 . ASN A 1 354 ? 51.875 9.339 42.023 1.00 32.51 ? 544 ASN A ND2 1 ATOM 2734 N N . LYS A 1 355 ? 53.998 13.892 44.688 1.00 21.14 ? 545 LYS A N 1 ATOM 2735 C CA . LYS A 1 355 ? 54.354 14.493 45.966 1.00 21.34 ? 545 LYS A CA 1 ATOM 2736 C C . LYS A 1 355 ? 53.194 14.295 46.931 1.00 21.63 ? 545 LYS A C 1 ATOM 2737 O O . LYS A 1 355 ? 52.071 14.707 46.652 1.00 23.10 ? 545 LYS A O 1 ATOM 2738 C CB . LYS A 1 355 ? 54.648 15.985 45.789 1.00 20.39 ? 545 LYS A CB 1 ATOM 2739 C CG . LYS A 1 355 ? 55.830 16.254 44.878 1.00 24.19 ? 545 LYS A CG 1 ATOM 2740 C CD . LYS A 1 355 ? 56.014 17.731 44.595 1.00 26.47 ? 545 LYS A CD 1 ATOM 2741 C CE . LYS A 1 355 ? 57.236 17.959 43.707 1.00 25.45 ? 545 LYS A CE 1 ATOM 2742 N NZ . LYS A 1 355 ? 57.439 19.403 43.390 1.00 26.37 ? 545 LYS A NZ 1 ATOM 2743 N N . ILE A 1 356 ? 53.469 13.650 48.059 1.00 20.39 ? 546 ILE A N 1 ATOM 2744 C CA . ILE A 1 356 ? 52.443 13.396 49.057 1.00 15.25 ? 546 ILE A CA 1 ATOM 2745 C C . ILE A 1 356 ? 52.459 14.468 50.131 1.00 14.90 ? 546 ILE A C 1 ATOM 2746 O O . ILE A 1 356 ? 53.505 14.789 50.683 1.00 21.34 ? 546 ILE A O 1 ATOM 2747 C CB . ILE A 1 356 ? 52.655 12.036 49.733 1.00 19.90 ? 546 ILE A CB 1 ATOM 2748 C CG1 . ILE A 1 356 ? 52.761 10.943 48.670 1.00 22.47 ? 546 ILE A CG1 1 ATOM 2749 C CG2 . ILE A 1 356 ? 51.503 11.741 50.681 1.00 17.00 ? 546 ILE A CG2 1 ATOM 2750 C CD1 . ILE A 1 356 ? 51.568 10.869 47.738 1.00 21.83 ? 546 ILE A CD1 1 ATOM 2751 N N . PRO A 1 357 ? 51.290 15.035 50.448 1.00 14.94 ? 547 PRO A N 1 ATOM 2752 C CA . PRO A 1 357 ? 51.214 16.075 51.473 1.00 15.65 ? 547 PRO A CA 1 ATOM 2753 C C . PRO A 1 357 ? 51.486 15.520 52.869 1.00 19.27 ? 547 PRO A C 1 ATOM 2754 O O . PRO A 1 357 ? 51.276 14.334 53.127 1.00 22.77 ? 547 PRO A O 1 ATOM 2755 C CB . PRO A 1 357 ? 49.786 16.586 51.326 1.00 14.65 ? 547 PRO A CB 1 ATOM 2756 C CG . PRO A 1 357 ? 49.044 15.345 50.953 1.00 5.34 ? 547 PRO A CG 1 ATOM 2757 C CD . PRO A 1 357 ? 49.951 14.736 49.910 1.00 11.60 ? 547 PRO A CD 1 ATOM 2758 N N . CYS A 1 358 ? 51.962 16.379 53.764 1.00 19.73 ? 548 CYS A N 1 ATOM 2759 C CA . CYS A 1 358 ? 52.232 15.968 55.134 1.00 19.80 ? 548 CYS A CA 1 ATOM 2760 C C . CYS A 1 358 ? 50.940 15.965 55.934 1.00 18.80 ? 548 CYS A C 1 ATOM 2761 O O . CYS A 1 358 ? 50.154 16.908 55.863 1.00 17.55 ? 548 CYS A O 1 ATOM 2762 C CB . CYS A 1 358 ? 53.181 16.938 55.833 1.00 23.30 ? 548 CYS A CB 1 ATOM 2763 S SG . CYS A 1 358 ? 54.940 16.889 55.398 1.00 24.32 ? 548 CYS A SG 1 ATOM 2764 N N . ALA A 1 359 ? 50.721 14.907 56.701 1.00 20.29 ? 549 ALA A N 1 ATOM 2765 C CA . ALA A 1 359 ? 49.542 14.846 57.543 1.00 18.39 ? 549 ALA A CA 1 ATOM 2766 C C . ALA A 1 359 ? 49.875 15.785 58.692 1.00 17.67 ? 549 ALA A C 1 ATOM 2767 O O . ALA A 1 359 ? 51.046 16.007 58.997 1.00 12.72 ? 549 ALA A O 1 ATOM 2768 C CB . ALA A 1 359 ? 49.334 13.437 58.059 1.00 20.88 ? 549 ALA A CB 1 ATOM 2769 N N . PRO A 1 360 ? 48.855 16.361 59.338 1.00 22.89 ? 550 PRO A N 1 ATOM 2770 C CA . PRO A 1 360 ? 49.083 17.281 60.458 1.00 28.03 ? 550 PRO A CA 1 ATOM 2771 C C . PRO A 1 360 ? 50.199 16.844 61.417 1.00 30.99 ? 550 PRO A C 1 ATOM 2772 O O . PRO A 1 360 ? 50.975 17.669 61.896 1.00 34.59 ? 550 PRO A O 1 ATOM 2773 C CB . PRO A 1 360 ? 47.717 17.325 61.132 1.00 28.14 ? 550 PRO A CB 1 ATOM 2774 C CG . PRO A 1 360 ? 46.785 17.251 59.950 1.00 21.36 ? 550 PRO A CG 1 ATOM 2775 C CD . PRO A 1 360 ? 47.412 16.169 59.095 1.00 20.59 ? 550 PRO A CD 1 ATOM 2776 N N . GLU A 1 361 ? 50.284 15.543 61.677 1.00 32.14 ? 551 GLU A N 1 ATOM 2777 C CA . GLU A 1 361 ? 51.289 15.000 62.585 1.00 28.71 ? 551 GLU A CA 1 ATOM 2778 C C . GLU A 1 361 ? 52.718 15.027 62.039 1.00 27.80 ? 551 GLU A C 1 ATOM 2779 O O . GLU A 1 361 ? 53.650 15.393 62.751 1.00 33.37 ? 551 GLU A O 1 ATOM 2780 C CB . GLU A 1 361 ? 50.939 13.553 62.964 1.00 27.61 ? 551 GLU A CB 1 ATOM 2781 C CG . GLU A 1 361 ? 49.490 13.316 63.395 1.00 38.87 ? 551 GLU A CG 1 ATOM 2782 C CD . GLU A 1 361 ? 48.533 13.142 62.217 1.00 42.12 ? 551 GLU A CD 1 ATOM 2783 O OE1 . GLU A 1 361 ? 47.321 12.937 62.449 1.00 39.93 ? 551 GLU A OE1 1 ATOM 2784 O OE2 . GLU A 1 361 ? 48.990 13.203 61.057 1.00 48.41 ? 551 GLU A OE2 1 ATOM 2785 N N . ASP A 1 362 ? 52.890 14.641 60.778 1.00 25.06 ? 552 ASP A N 1 ATOM 2786 C CA . ASP A 1 362 ? 54.217 14.584 60.163 1.00 21.41 ? 552 ASP A CA 1 ATOM 2787 C C . ASP A 1 362 ? 54.730 15.899 59.574 1.00 18.42 ? 552 ASP A C 1 ATOM 2788 O O . ASP A 1 362 ? 55.751 15.930 58.885 1.00 12.98 ? 552 ASP A O 1 ATOM 2789 C CB . ASP A 1 362 ? 54.219 13.510 59.081 1.00 22.66 ? 552 ASP A CB 1 ATOM 2790 C CG . ASP A 1 362 ? 53.664 12.195 59.575 1.00 26.66 ? 552 ASP A CG 1 ATOM 2791 O OD1 . ASP A 1 362 ? 54.149 11.707 60.618 1.00 30.18 ? 552 ASP A OD1 1 ATOM 2792 O OD2 . ASP A 1 362 ? 52.745 11.651 58.925 1.00 26.91 ? 552 ASP A OD2 1 ATOM 2793 N N . VAL A 1 363 ? 54.020 16.981 59.860 1.00 16.66 ? 553 VAL A N 1 ATOM 2794 C CA . VAL A 1 363 ? 54.369 18.302 59.365 1.00 10.82 ? 553 VAL A CA 1 ATOM 2795 C C . VAL A 1 363 ? 55.856 18.656 59.453 1.00 14.64 ? 553 VAL A C 1 ATOM 2796 O O . VAL A 1 363 ? 56.430 19.173 58.495 1.00 19.71 ? 553 VAL A O 1 ATOM 2797 C CB . VAL A 1 363 ? 53.524 19.364 60.099 1.00 7.33 ? 553 VAL A CB 1 ATOM 2798 C CG1 . VAL A 1 363 ? 54.318 20.619 60.318 1.00 3.45 ? 553 VAL A CG1 1 ATOM 2799 C CG2 . VAL A 1 363 ? 52.279 19.667 59.288 1.00 3.36 ? 553 VAL A CG2 1 ATOM 2800 N N . LYS A 1 364 ? 56.479 18.374 60.593 1.00 16.51 ? 554 LYS A N 1 ATOM 2801 C CA . LYS A 1 364 ? 57.894 18.684 60.798 1.00 14.81 ? 554 LYS A CA 1 ATOM 2802 C C . LYS A 1 364 ? 58.880 17.799 60.033 1.00 17.78 ? 554 LYS A C 1 ATOM 2803 O O . LYS A 1 364 ? 60.091 17.963 60.172 1.00 21.20 ? 554 LYS A O 1 ATOM 2804 C CB . LYS A 1 364 ? 58.231 18.610 62.288 1.00 15.47 ? 554 LYS A CB 1 ATOM 2805 C CG . LYS A 1 364 ? 57.601 19.693 63.141 1.00 17.51 ? 554 LYS A CG 1 ATOM 2806 C CD . LYS A 1 364 ? 58.310 21.022 62.957 1.00 23.78 ? 554 LYS A CD 1 ATOM 2807 C CE . LYS A 1 364 ? 57.769 22.062 63.924 1.00 30.49 ? 554 LYS A CE 1 ATOM 2808 N NZ . LYS A 1 364 ? 57.939 21.644 65.345 1.00 32.16 ? 554 LYS A NZ 1 ATOM 2809 N N . CYS A 1 365 ? 58.380 16.862 59.234 1.00 18.54 ? 555 CYS A N 1 ATOM 2810 C CA . CYS A 1 365 ? 59.270 15.983 58.483 1.00 21.25 ? 555 CYS A CA 1 ATOM 2811 C C . CYS A 1 365 ? 59.249 16.212 56.980 1.00 19.38 ? 555 CYS A C 1 ATOM 2812 O O . CYS A 1 365 ? 59.823 15.428 56.226 1.00 15.94 ? 555 CYS A O 1 ATOM 2813 C CB . CYS A 1 365 ? 58.949 14.514 58.773 1.00 24.89 ? 555 CYS A CB 1 ATOM 2814 S SG . CYS A 1 365 ? 59.308 14.016 60.486 1.00 33.80 ? 555 CYS A SG 1 ATOM 2815 N N . GLY A 1 366 ? 58.586 17.279 56.544 1.00 19.46 ? 556 GLY A N 1 ATOM 2816 C CA . GLY A 1 366 ? 58.532 17.572 55.123 1.00 17.73 ? 556 GLY A CA 1 ATOM 2817 C C . GLY A 1 366 ? 59.585 18.596 54.741 1.00 19.41 ? 556 GLY A C 1 ATOM 2818 O O . GLY A 1 366 ? 60.776 18.413 55.010 1.00 15.31 ? 556 GLY A O 1 ATOM 2819 N N . ARG A 1 367 ? 59.141 19.677 54.109 1.00 16.48 ? 557 ARG A N 1 ATOM 2820 C CA . ARG A 1 367 ? 60.030 20.754 53.697 1.00 12.21 ? 557 ARG A CA 1 ATOM 2821 C C . ARG A 1 367 ? 60.494 21.462 54.962 1.00 12.53 ? 557 ARG A C 1 ATOM 2822 O O . ARG A 1 367 ? 59.732 21.592 55.915 1.00 13.09 ? 557 ARG A O 1 ATOM 2823 C CB . ARG A 1 367 ? 59.270 21.735 52.792 1.00 12.51 ? 557 ARG A CB 1 ATOM 2824 C CG . ARG A 1 367 ? 60.072 22.930 52.276 1.00 3.08 ? 557 ARG A CG 1 ATOM 2825 C CD . ARG A 1 367 ? 61.173 22.516 51.308 1.00 8.44 ? 557 ARG A CD 1 ATOM 2826 N NE . ARG A 1 367 ? 60.667 21.704 50.205 1.00 6.01 ? 557 ARG A NE 1 ATOM 2827 C CZ . ARG A 1 367 ? 61.424 21.215 49.227 1.00 6.20 ? 557 ARG A CZ 1 ATOM 2828 N NH1 . ARG A 1 367 ? 62.728 21.459 49.208 1.00 4.76 ? 557 ARG A NH1 1 ATOM 2829 N NH2 . ARG A 1 367 ? 60.879 20.468 48.276 1.00 9.98 ? 557 ARG A NH2 1 ATOM 2830 N N . LEU A 1 368 ? 61.748 21.899 54.977 1.00 15.21 ? 558 LEU A N 1 ATOM 2831 C CA . LEU A 1 368 ? 62.298 22.607 56.127 1.00 12.91 ? 558 LEU A CA 1 ATOM 2832 C C . LEU A 1 368 ? 62.085 24.112 55.984 1.00 13.08 ? 558 LEU A C 1 ATOM 2833 O O . LEU A 1 368 ? 62.321 24.679 54.917 1.00 14.91 ? 558 LEU A O 1 ATOM 2834 C CB . LEU A 1 368 ? 63.795 22.327 56.254 1.00 14.80 ? 558 LEU A CB 1 ATOM 2835 C CG . LEU A 1 368 ? 64.582 23.289 57.155 1.00 14.68 ? 558 LEU A CG 1 ATOM 2836 C CD1 . LEU A 1 368 ? 64.117 23.159 58.600 1.00 12.67 ? 558 LEU A CD1 1 ATOM 2837 C CD2 . LEU A 1 368 ? 66.062 22.987 57.042 1.00 13.30 ? 558 LEU A CD2 1 ATOM 2838 N N . TYR A 1 369 ? 61.640 24.753 57.059 1.00 12.60 ? 559 TYR A N 1 ATOM 2839 C CA . TYR A 1 369 ? 61.418 26.196 57.055 1.00 9.38 ? 559 TYR A CA 1 ATOM 2840 C C . TYR A 1 369 ? 62.311 26.834 58.111 1.00 13.98 ? 559 TYR A C 1 ATOM 2841 O O . TYR A 1 369 ? 62.502 26.275 59.189 1.00 14.43 ? 559 TYR A O 1 ATOM 2842 C CB . TYR A 1 369 ? 59.948 26.515 57.342 1.00 11.02 ? 559 TYR A CB 1 ATOM 2843 C CG . TYR A 1 369 ? 59.000 25.907 56.338 1.00 18.29 ? 559 TYR A CG 1 ATOM 2844 C CD1 . TYR A 1 369 ? 58.530 24.604 56.494 1.00 19.74 ? 559 TYR A CD1 1 ATOM 2845 C CD2 . TYR A 1 369 ? 58.615 26.615 55.200 1.00 22.07 ? 559 TYR A CD2 1 ATOM 2846 C CE1 . TYR A 1 369 ? 57.701 24.019 55.539 1.00 24.87 ? 559 TYR A CE1 1 ATOM 2847 C CE2 . TYR A 1 369 ? 57.789 26.039 54.236 1.00 23.95 ? 559 TYR A CE2 1 ATOM 2848 C CZ . TYR A 1 369 ? 57.337 24.741 54.411 1.00 27.07 ? 559 TYR A CZ 1 ATOM 2849 O OH . TYR A 1 369 ? 56.528 24.164 53.455 1.00 24.45 ? 559 TYR A OH 1 ATOM 2850 N N . CYS A 1 370 ? 62.860 28.003 57.802 1.00 15.80 ? 560 CYS A N 1 ATOM 2851 C CA . CYS A 1 370 ? 63.749 28.681 58.734 1.00 23.58 ? 560 CYS A CA 1 ATOM 2852 C C . CYS A 1 370 ? 63.416 30.170 58.872 1.00 28.15 ? 560 CYS A C 1 ATOM 2853 O O . CYS A 1 370 ? 62.881 30.781 57.948 1.00 31.57 ? 560 CYS A O 1 ATOM 2854 C CB . CYS A 1 370 ? 65.196 28.497 58.270 1.00 20.26 ? 560 CYS A CB 1 ATOM 2855 S SG . CYS A 1 370 ? 65.645 26.765 57.896 1.00 24.54 ? 560 CYS A SG 1 ATOM 2856 N N . LYS A 1 371 ? 63.730 30.747 60.030 1.00 32.61 ? 561 LYS A N 1 ATOM 2857 C CA . LYS A 1 371 ? 63.450 32.159 60.286 1.00 37.27 ? 561 LYS A CA 1 ATOM 2858 C C . LYS A 1 371 ? 64.706 33.024 60.195 1.00 37.70 ? 561 LYS A C 1 ATOM 2859 O O . LYS A 1 371 ? 65.762 32.669 60.720 1.00 33.34 ? 561 LYS A O 1 ATOM 2860 C CB . LYS A 1 371 ? 62.816 32.337 61.674 1.00 38.45 ? 561 LYS A CB 1 ATOM 2861 C CG . LYS A 1 371 ? 63.782 32.101 62.827 1.00 44.57 ? 561 LYS A CG 1 ATOM 2862 C CD . LYS A 1 371 ? 63.194 32.496 64.176 1.00 44.74 ? 561 LYS A CD 1 ATOM 2863 C CE . LYS A 1 371 ? 62.097 31.546 64.620 1.00 49.43 ? 561 LYS A CE 1 ATOM 2864 N NZ . LYS A 1 371 ? 61.612 31.875 65.991 1.00 50.73 ? 561 LYS A NZ 1 ATOM 2865 N N . ASP A 1 372 ? 64.581 34.165 59.527 1.00 43.01 ? 562 ASP A N 1 ATOM 2866 C CA . ASP A 1 372 ? 65.701 35.085 59.371 1.00 49.06 ? 562 ASP A CA 1 ATOM 2867 C C . ASP A 1 372 ? 65.571 36.216 60.392 1.00 50.26 ? 562 ASP A C 1 ATOM 2868 O O . ASP A 1 372 ? 64.622 37.006 60.350 1.00 47.53 ? 562 ASP A O 1 ATOM 2869 C CB . ASP A 1 372 ? 65.718 35.651 57.950 1.00 53.98 ? 562 ASP A CB 1 ATOM 2870 C CG . ASP A 1 372 ? 66.954 36.476 57.668 1.00 57.39 ? 562 ASP A CG 1 ATOM 2871 O OD1 . ASP A 1 372 ? 67.204 37.436 58.424 1.00 62.28 ? 562 ASP A OD1 1 ATOM 2872 O OD2 . ASP A 1 372 ? 67.672 36.169 56.692 1.00 56.59 ? 562 ASP A OD2 1 ATOM 2873 N N . ASN A 1 373 ? 66.537 36.292 61.302 1.00 47.61 ? 563 ASN A N 1 ATOM 2874 C CA . ASN A 1 373 ? 66.526 37.303 62.353 1.00 45.34 ? 563 ASN A CA 1 ATOM 2875 C C . ASN A 1 373 ? 67.312 38.568 61.998 1.00 43.24 ? 563 ASN A C 1 ATOM 2876 O O . ASN A 1 373 ? 67.880 39.215 62.877 1.00 44.45 ? 563 ASN A O 1 ATOM 2877 C CB . ASN A 1 373 ? 67.086 36.699 63.643 1.00 46.62 ? 563 ASN A CB 1 ATOM 2878 C CG . ASN A 1 373 ? 66.707 37.495 64.873 1.00 48.17 ? 563 ASN A CG 1 ATOM 2879 O OD1 . ASN A 1 373 ? 65.546 37.502 65.288 1.00 48.35 ? 563 ASN A OD1 1 ATOM 2880 N ND2 . ASN A 1 373 ? 67.684 38.176 65.463 1.00 49.19 ? 563 ASN A ND2 1 ATOM 2881 N N . SER A 1 374 ? 67.343 38.922 60.717 1.00 38.68 ? 564 SER A N 1 ATOM 2882 C CA . SER A 1 374 ? 68.062 40.115 60.284 1.00 34.12 ? 564 SER A CA 1 ATOM 2883 C C . SER A 1 374 ? 67.113 41.309 60.259 1.00 33.66 ? 564 SER A C 1 ATOM 2884 O O . SER A 1 374 ? 65.897 41.146 60.343 1.00 39.41 ? 564 SER A O 1 ATOM 2885 C CB . SER A 1 374 ? 68.659 39.899 58.892 1.00 35.03 ? 564 SER A CB 1 ATOM 2886 O OG . SER A 1 374 ? 67.643 39.797 57.909 1.00 38.56 ? 564 SER A OG 1 ATOM 2887 N N . PRO A 1 375 ? 67.657 42.529 60.146 1.00 34.16 ? 565 PRO A N 1 ATOM 2888 C CA . PRO A 1 375 ? 66.841 43.749 60.116 1.00 34.00 ? 565 PRO A CA 1 ATOM 2889 C C . PRO A 1 375 ? 65.926 43.874 58.902 1.00 38.28 ? 565 PRO A C 1 ATOM 2890 O O . PRO A 1 375 ? 66.361 43.680 57.767 1.00 43.52 ? 565 PRO A O 1 ATOM 2891 C CB . PRO A 1 375 ? 67.885 44.862 60.155 1.00 30.58 ? 565 PRO A CB 1 ATOM 2892 C CG . PRO A 1 375 ? 69.018 44.233 60.908 1.00 28.90 ? 565 PRO A CG 1 ATOM 2893 C CD . PRO A 1 375 ? 69.084 42.867 60.282 1.00 29.37 ? 565 PRO A CD 1 ATOM 2894 N N . GLY A 1 376 ? 64.661 44.200 59.157 1.00 42.55 ? 566 GLY A N 1 ATOM 2895 C CA . GLY A 1 376 ? 63.683 44.373 58.095 1.00 48.07 ? 566 GLY A CA 1 ATOM 2896 C C . GLY A 1 376 ? 63.374 43.187 57.195 1.00 54.76 ? 566 GLY A C 1 ATOM 2897 O O . GLY A 1 376 ? 62.439 43.256 56.395 1.00 55.03 ? 566 GLY A O 1 ATOM 2898 N N . GLN A 1 377 ? 64.145 42.106 57.322 1.00 61.39 ? 567 GLN A N 1 ATOM 2899 C CA . GLN A 1 377 ? 63.971 40.898 56.505 1.00 61.15 ? 567 GLN A CA 1 ATOM 2900 C C . GLN A 1 377 ? 62.499 40.613 56.196 1.00 61.71 ? 567 GLN A C 1 ATOM 2901 O O . GLN A 1 377 ? 62.096 40.605 55.032 1.00 63.75 ? 567 GLN A O 1 ATOM 2902 C CB . GLN A 1 377 ? 64.599 39.696 57.214 1.00 64.35 ? 567 GLN A CB 1 ATOM 2903 C CG . GLN A 1 377 ? 65.061 38.588 56.274 1.00 69.31 ? 567 GLN A CG 1 ATOM 2904 C CD . GLN A 1 377 ? 63.919 37.931 55.527 1.00 68.92 ? 567 GLN A CD 1 ATOM 2905 O OE1 . GLN A 1 377 ? 63.003 37.381 56.136 1.00 71.43 ? 567 GLN A OE1 1 ATOM 2906 N NE2 . GLN A 1 377 ? 63.969 37.981 54.199 1.00 68.85 ? 567 GLN A NE2 1 ATOM 2907 N N . ASN A 1 378 ? 61.713 40.362 57.240 1.00 58.73 ? 568 ASN A N 1 ATOM 2908 C CA . ASN A 1 378 ? 60.279 40.120 57.103 1.00 57.99 ? 568 ASN A CA 1 ATOM 2909 C C . ASN A 1 378 ? 59.808 38.690 56.804 1.00 54.30 ? 568 ASN A C 1 ATOM 2910 O O . ASN A 1 378 ? 58.734 38.300 57.265 1.00 57.51 ? 568 ASN A O 1 ATOM 2911 C CB . ASN A 1 378 ? 59.691 41.083 56.058 1.00 63.12 ? 568 ASN A CB 1 ATOM 2912 C CG . ASN A 1 378 ? 58.175 41.015 55.980 1.00 66.67 ? 568 ASN A CG 1 ATOM 2913 O OD1 . ASN A 1 378 ? 57.477 41.287 56.959 1.00 69.43 ? 568 ASN A OD1 1 ATOM 2914 N ND2 . ASN A 1 378 ? 57.657 40.655 54.808 1.00 64.15 ? 568 ASN A ND2 1 ATOM 2915 N N . ASN A 1 379 ? 60.576 37.907 56.045 1.00 43.12 ? 569 ASN A N 1 ATOM 2916 C CA . ASN A 1 379 ? 60.155 36.533 55.731 1.00 37.57 ? 569 ASN A CA 1 ATOM 2917 C C . ASN A 1 379 ? 60.369 35.565 56.898 1.00 30.90 ? 569 ASN A C 1 ATOM 2918 O O . ASN A 1 379 ? 61.502 35.214 57.228 1.00 27.73 ? 569 ASN A O 1 ATOM 2919 C CB . ASN A 1 379 ? 60.895 35.996 54.501 1.00 38.03 ? 569 ASN A CB 1 ATOM 2920 C CG . ASN A 1 379 ? 60.350 34.648 54.033 1.00 35.89 ? 569 ASN A CG 1 ATOM 2921 O OD1 . ASN A 1 379 ? 60.913 34.014 53.143 1.00 35.98 ? 569 ASN A OD1 1 ATOM 2922 N ND2 . ASN A 1 379 ? 59.244 34.215 54.628 1.00 31.57 ? 569 ASN A ND2 1 ATOM 2923 N N . PRO A 1 380 ? 59.272 35.104 57.522 1.00 26.93 ? 570 PRO A N 1 ATOM 2924 C CA . PRO A 1 380 ? 59.328 34.178 58.654 1.00 25.88 ? 570 PRO A CA 1 ATOM 2925 C C . PRO A 1 380 ? 59.406 32.700 58.268 1.00 25.92 ? 570 PRO A C 1 ATOM 2926 O O . PRO A 1 380 ? 59.814 31.864 59.075 1.00 25.87 ? 570 PRO A O 1 ATOM 2927 C CB . PRO A 1 380 ? 58.048 34.502 59.405 1.00 24.82 ? 570 PRO A CB 1 ATOM 2928 C CG . PRO A 1 380 ? 57.089 34.719 58.278 1.00 27.14 ? 570 PRO A CG 1 ATOM 2929 C CD . PRO A 1 380 ? 57.887 35.558 57.292 1.00 26.07 ? 570 PRO A CD 1 ATOM 2930 N N . CYS A 1 381 ? 59.013 32.376 57.043 1.00 23.44 ? 571 CYS A N 1 ATOM 2931 C CA . CYS A 1 381 ? 59.045 30.988 56.602 1.00 25.68 ? 571 CYS A CA 1 ATOM 2932 C C . CYS A 1 381 ? 59.997 30.760 55.432 1.00 23.35 ? 571 CYS A C 1 ATOM 2933 O O . CYS A 1 381 ? 59.603 30.212 54.405 1.00 22.75 ? 571 CYS A O 1 ATOM 2934 C CB . CYS A 1 381 ? 57.643 30.518 56.197 1.00 23.91 ? 571 CYS A CB 1 ATOM 2935 S SG . CYS A 1 381 ? 56.317 30.693 57.440 1.00 30.89 ? 571 CYS A SG 1 ATOM 2936 N N . LYS A 1 382 ? 61.248 31.174 55.578 1.00 23.77 ? 572 LYS A N 1 ATOM 2937 C CA . LYS A 1 382 ? 62.206 30.974 54.501 1.00 25.65 ? 572 LYS A CA 1 ATOM 2938 C C . LYS A 1 382 ? 62.356 29.478 54.248 1.00 21.52 ? 572 LYS A C 1 ATOM 2939 O O . LYS A 1 382 ? 62.364 28.673 55.177 1.00 18.85 ? 572 LYS A O 1 ATOM 2940 C CB . LYS A 1 382 ? 63.566 31.595 54.847 1.00 29.47 ? 572 LYS A CB 1 ATOM 2941 C CG . LYS A 1 382 ? 64.610 31.441 53.743 1.00 40.91 ? 572 LYS A CG 1 ATOM 2942 C CD . LYS A 1 382 ? 64.063 31.890 52.384 1.00 47.57 ? 572 LYS A CD 1 ATOM 2943 C CE . LYS A 1 382 ? 65.057 31.623 51.256 1.00 51.54 ? 572 LYS A CE 1 ATOM 2944 N NZ . LYS A 1 382 ? 64.496 31.958 49.911 1.00 45.62 ? 572 LYS A NZ 1 ATOM 2945 N N . MET A 1 383 ? 62.471 29.114 52.979 1.00 19.43 ? 573 MET A N 1 ATOM 2946 C CA . MET A 1 383 ? 62.599 27.722 52.593 1.00 19.37 ? 573 MET A CA 1 ATOM 2947 C C . MET A 1 383 ? 63.419 27.638 51.311 1.00 22.13 ? 573 MET A C 1 ATOM 2948 O O . MET A 1 383 ? 63.654 28.652 50.654 1.00 26.10 ? 573 MET A O 1 ATOM 2949 C CB . MET A 1 383 ? 61.191 27.131 52.415 1.00 17.35 ? 573 MET A CB 1 ATOM 2950 C CG . MET A 1 383 ? 61.041 26.015 51.392 1.00 20.84 ? 573 MET A CG 1 ATOM 2951 S SD . MET A 1 383 ? 60.959 26.617 49.683 1.00 20.53 ? 573 MET A SD 1 ATOM 2952 C CE . MET A 1 383 ? 59.294 27.241 49.617 1.00 19.44 ? 573 MET A CE 1 ATOM 2953 N N . PHE A 1 384 ? 63.876 26.438 50.970 1.00 20.67 ? 574 PHE A N 1 ATOM 2954 C CA . PHE A 1 384 ? 64.660 26.249 49.759 1.00 21.94 ? 574 PHE A CA 1 ATOM 2955 C C . PHE A 1 384 ? 64.068 25.193 48.823 1.00 23.58 ? 574 PHE A C 1 ATOM 2956 O O . PHE A 1 384 ? 63.765 24.075 49.245 1.00 24.62 ? 574 PHE A O 1 ATOM 2957 C CB . PHE A 1 384 ? 66.101 25.868 50.116 1.00 20.49 ? 574 PHE A CB 1 ATOM 2958 C CG . PHE A 1 384 ? 66.959 25.571 48.921 1.00 19.54 ? 574 PHE A CG 1 ATOM 2959 C CD1 . PHE A 1 384 ? 66.858 24.352 48.259 1.00 16.93 ? 574 PHE A CD1 1 ATOM 2960 C CD2 . PHE A 1 384 ? 67.833 26.533 48.425 1.00 22.38 ? 574 PHE A CD2 1 ATOM 2961 C CE1 . PHE A 1 384 ? 67.610 24.097 47.117 1.00 22.79 ? 574 PHE A CE1 1 ATOM 2962 C CE2 . PHE A 1 384 ? 68.592 26.288 47.283 1.00 23.31 ? 574 PHE A CE2 1 ATOM 2963 C CZ . PHE A 1 384 ? 68.479 25.068 46.626 1.00 24.75 ? 574 PHE A CZ 1 ATOM 2964 N N . TYR A 1 385 ? 63.907 25.563 47.554 1.00 22.26 ? 575 TYR A N 1 ATOM 2965 C CA . TYR A 1 385 ? 63.387 24.657 46.532 1.00 20.91 ? 575 TYR A CA 1 ATOM 2966 C C . TYR A 1 385 ? 64.055 24.912 45.186 1.00 19.57 ? 575 TYR A C 1 ATOM 2967 O O . TYR A 1 385 ? 64.230 26.056 44.772 1.00 19.04 ? 575 TYR A O 1 ATOM 2968 C CB . TYR A 1 385 ? 61.876 24.811 46.340 1.00 21.52 ? 575 TYR A CB 1 ATOM 2969 C CG . TYR A 1 385 ? 61.368 23.962 45.190 1.00 20.81 ? 575 TYR A CG 1 ATOM 2970 C CD1 . TYR A 1 385 ? 61.164 22.593 45.347 1.00 24.70 ? 575 TYR A CD1 1 ATOM 2971 C CD2 . TYR A 1 385 ? 61.171 24.511 43.924 1.00 21.64 ? 575 TYR A CD2 1 ATOM 2972 C CE1 . TYR A 1 385 ? 60.780 21.788 44.272 1.00 21.33 ? 575 TYR A CE1 1 ATOM 2973 C CE2 . TYR A 1 385 ? 60.790 23.715 42.842 1.00 21.35 ? 575 TYR A CE2 1 ATOM 2974 C CZ . TYR A 1 385 ? 60.596 22.354 43.023 1.00 20.94 ? 575 TYR A CZ 1 ATOM 2975 O OH . TYR A 1 385 ? 60.220 21.557 41.959 1.00 13.18 ? 575 TYR A OH 1 ATOM 2976 N N . SER A 1 386 ? 64.409 23.833 44.503 1.00 18.53 ? 576 SER A N 1 ATOM 2977 C CA . SER A 1 386 ? 65.040 23.918 43.198 1.00 16.88 ? 576 SER A CA 1 ATOM 2978 C C . SER A 1 386 ? 64.655 22.672 42.427 1.00 18.32 ? 576 SER A C 1 ATOM 2979 O O . SER A 1 386 ? 65.001 21.564 42.824 1.00 26.35 ? 576 SER A O 1 ATOM 2980 C CB . SER A 1 386 ? 66.556 23.983 43.349 1.00 23.11 ? 576 SER A CB 1 ATOM 2981 O OG . SER A 1 386 ? 67.185 24.019 42.083 1.00 33.96 ? 576 SER A OG 1 ATOM 2982 N N . ASN A 1 387 ? 63.932 22.844 41.328 1.00 19.70 ? 577 ASN A N 1 ATOM 2983 C CA . ASN A 1 387 ? 63.506 21.700 40.533 1.00 19.36 ? 577 ASN A CA 1 ATOM 2984 C C . ASN A 1 387 ? 64.710 20.936 39.997 1.00 19.97 ? 577 ASN A C 1 ATOM 2985 O O . ASN A 1 387 ? 64.559 19.945 39.292 1.00 26.14 ? 577 ASN A O 1 ATOM 2986 C CB . ASN A 1 387 ? 62.598 22.155 39.383 1.00 16.50 ? 577 ASN A CB 1 ATOM 2987 C CG . ASN A 1 387 ? 63.363 22.784 38.239 1.00 12.57 ? 577 ASN A CG 1 ATOM 2988 O OD1 . ASN A 1 387 ? 64.339 23.502 38.446 1.00 24.05 ? 577 ASN A OD1 1 ATOM 2989 N ND2 . ASN A 1 387 ? 62.911 22.529 37.021 1.00 7.58 ? 577 ASN A ND2 1 ATOM 2990 N N . GLU A 1 388 ? 65.904 21.407 40.343 1.00 22.39 ? 578 GLU A N 1 ATOM 2991 C CA . GLU A 1 388 ? 67.149 20.770 39.921 1.00 24.06 ? 578 GLU A CA 1 ATOM 2992 C C . GLU A 1 388 ? 67.398 19.543 40.802 1.00 24.27 ? 578 GLU A C 1 ATOM 2993 O O . GLU A 1 388 ? 67.998 18.560 40.370 1.00 18.62 ? 578 GLU A O 1 ATOM 2994 C CB . GLU A 1 388 ? 68.303 21.768 40.048 1.00 24.04 ? 578 GLU A CB 1 ATOM 2995 C CG . GLU A 1 388 ? 69.673 21.229 39.677 1.00 29.03 ? 578 GLU A CG 1 ATOM 2996 C CD . GLU A 1 388 ? 70.704 22.341 39.510 1.00 37.60 ? 578 GLU A CD 1 ATOM 2997 O OE1 . GLU A 1 388 ? 70.930 23.112 40.469 1.00 35.14 ? 578 GLU A OE1 1 ATOM 2998 O OE2 . GLU A 1 388 ? 71.286 22.446 38.410 1.00 42.87 ? 578 GLU A OE2 1 ATOM 2999 N N . ASP A 1 389 ? 66.920 19.623 42.040 1.00 23.70 ? 579 ASP A N 1 ATOM 3000 C CA . ASP A 1 389 ? 67.041 18.550 43.020 1.00 20.39 ? 579 ASP A CA 1 ATOM 3001 C C . ASP A 1 389 ? 66.080 18.860 44.167 1.00 20.02 ? 579 ASP A C 1 ATOM 3002 O O . ASP A 1 389 ? 66.455 19.468 45.171 1.00 18.28 ? 579 ASP A O 1 ATOM 3003 C CB . ASP A 1 389 ? 68.477 18.455 43.533 1.00 23.13 ? 579 ASP A CB 1 ATOM 3004 C CG . ASP A 1 389 ? 68.617 17.480 44.681 1.00 27.87 ? 579 ASP A CG 1 ATOM 3005 O OD1 . ASP A 1 389 ? 67.871 16.478 44.699 1.00 29.09 ? 579 ASP A OD1 1 ATOM 3006 O OD2 . ASP A 1 389 ? 69.473 17.711 45.559 1.00 31.00 ? 579 ASP A OD2 1 ATOM 3007 N N . GLU A 1 390 ? 64.835 18.433 43.998 1.00 16.37 ? 580 GLU A N 1 ATOM 3008 C CA . GLU A 1 390 ? 63.778 18.676 44.968 1.00 15.59 ? 580 GLU A CA 1 ATOM 3009 C C . GLU A 1 390 ? 64.035 18.229 46.402 1.00 18.64 ? 580 GLU A C 1 ATOM 3010 O O . GLU A 1 390 ? 63.458 18.792 47.339 1.00 17.37 ? 580 GLU A O 1 ATOM 3011 C CB . GLU A 1 390 ? 62.483 18.049 44.466 1.00 13.48 ? 580 GLU A CB 1 ATOM 3012 C CG . GLU A 1 390 ? 62.081 18.535 43.094 1.00 10.88 ? 580 GLU A CG 1 ATOM 3013 C CD . GLU A 1 390 ? 60.710 18.052 42.692 1.00 12.35 ? 580 GLU A CD 1 ATOM 3014 O OE1 . GLU A 1 390 ? 60.499 16.819 42.659 1.00 10.69 ? 580 GLU A OE1 1 ATOM 3015 O OE2 . GLU A 1 390 ? 59.844 18.908 42.410 1.00 16.92 ? 580 GLU A OE2 1 ATOM 3016 N N . HIS A 1 391 ? 64.890 17.227 46.583 1.00 17.81 ? 581 HIS A N 1 ATOM 3017 C CA . HIS A 1 391 ? 65.182 16.732 47.924 1.00 15.24 ? 581 HIS A CA 1 ATOM 3018 C C . HIS A 1 391 ? 65.952 17.758 48.745 1.00 13.06 ? 581 HIS A C 1 ATOM 3019 O O . HIS A 1 391 ? 65.784 17.842 49.961 1.00 14.20 ? 581 HIS A O 1 ATOM 3020 C CB . HIS A 1 391 ? 65.978 15.425 47.864 1.00 16.43 ? 581 HIS A CB 1 ATOM 3021 C CG . HIS A 1 391 ? 66.235 14.824 49.210 1.00 25.65 ? 581 HIS A CG 1 ATOM 3022 N ND1 . HIS A 1 391 ? 65.218 14.405 50.042 1.00 29.17 ? 581 HIS A ND1 1 ATOM 3023 C CD2 . HIS A 1 391 ? 67.388 14.615 49.890 1.00 29.28 ? 581 HIS A CD2 1 ATOM 3024 C CE1 . HIS A 1 391 ? 65.733 13.966 51.177 1.00 31.23 ? 581 HIS A CE1 1 ATOM 3025 N NE2 . HIS A 1 391 ? 67.047 14.083 51.111 1.00 32.10 ? 581 HIS A NE2 1 ATOM 3026 N N . LYS A 1 392 ? 66.804 18.531 48.081 1.00 9.42 ? 582 LYS A N 1 ATOM 3027 C CA . LYS A 1 392 ? 67.577 19.558 48.763 1.00 10.13 ? 582 LYS A CA 1 ATOM 3028 C C . LYS A 1 392 ? 66.595 20.518 49.435 1.00 13.79 ? 582 LYS A C 1 ATOM 3029 O O . LYS A 1 392 ? 65.677 21.027 48.792 1.00 15.18 ? 582 LYS A O 1 ATOM 3030 C CB . LYS A 1 392 ? 68.462 20.295 47.751 1.00 11.60 ? 582 LYS A CB 1 ATOM 3031 C CG . LYS A 1 392 ? 69.281 21.444 48.322 1.00 17.29 ? 582 LYS A CG 1 ATOM 3032 C CD . LYS A 1 392 ? 70.448 21.782 47.401 1.00 27.78 ? 582 LYS A CD 1 ATOM 3033 C CE . LYS A 1 392 ? 70.954 23.207 47.605 1.00 34.74 ? 582 LYS A CE 1 ATOM 3034 N NZ . LYS A 1 392 ? 71.261 23.521 49.025 1.00 44.61 ? 582 LYS A NZ 1 ATOM 3035 N N . GLY A 1 393 ? 66.776 20.746 50.733 1.00 13.18 ? 583 GLY A N 1 ATOM 3036 C CA . GLY A 1 393 ? 65.881 21.635 51.456 1.00 7.88 ? 583 GLY A CA 1 ATOM 3037 C C . GLY A 1 393 ? 64.872 20.854 52.279 1.00 12.61 ? 583 GLY A C 1 ATOM 3038 O O . GLY A 1 393 ? 64.200 21.402 53.160 1.00 7.95 ? 583 GLY A O 1 ATOM 3039 N N . MET A 1 394 ? 64.758 19.564 51.981 1.00 13.02 ? 584 MET A N 1 ATOM 3040 C CA . MET A 1 394 ? 63.846 18.691 52.706 1.00 13.02 ? 584 MET A CA 1 ATOM 3041 C C . MET A 1 394 ? 64.519 18.306 54.015 1.00 14.42 ? 584 MET A C 1 ATOM 3042 O O . MET A 1 394 ? 65.745 18.201 54.074 1.00 17.87 ? 584 MET A O 1 ATOM 3043 C CB . MET A 1 394 ? 63.553 17.424 51.896 1.00 9.87 ? 584 MET A CB 1 ATOM 3044 C CG . MET A 1 394 ? 62.681 17.633 50.669 1.00 12.49 ? 584 MET A CG 1 ATOM 3045 S SD . MET A 1 394 ? 61.019 18.200 51.083 1.00 19.40 ? 584 MET A SD 1 ATOM 3046 C CE . MET A 1 394 ? 60.241 16.678 51.558 1.00 7.10 ? 584 MET A CE 1 ATOM 3047 N N . VAL A 1 395 ? 63.723 18.112 55.062 1.00 13.40 ? 585 VAL A N 1 ATOM 3048 C CA . VAL A 1 395 ? 64.258 17.722 56.360 1.00 9.92 ? 585 VAL A CA 1 ATOM 3049 C C . VAL A 1 395 ? 65.012 16.404 56.214 1.00 10.56 ? 585 VAL A C 1 ATOM 3050 O O . VAL A 1 395 ? 64.523 15.462 55.593 1.00 15.26 ? 585 VAL A O 1 ATOM 3051 C CB . VAL A 1 395 ? 63.126 17.542 57.397 1.00 12.95 ? 585 VAL A CB 1 ATOM 3052 C CG1 . VAL A 1 395 ? 63.632 16.764 58.602 1.00 13.92 ? 585 VAL A CG1 1 ATOM 3053 C CG2 . VAL A 1 395 ? 62.616 18.898 57.842 1.00 15.34 ? 585 VAL A CG2 1 ATOM 3054 N N . LEU A 1 396 ? 66.208 16.336 56.779 1.00 6.08 ? 586 LEU A N 1 ATOM 3055 C CA . LEU A 1 396 ? 66.992 15.116 56.689 1.00 11.80 ? 586 LEU A CA 1 ATOM 3056 C C . LEU A 1 396 ? 66.355 13.998 57.510 1.00 14.11 ? 586 LEU A C 1 ATOM 3057 O O . LEU A 1 396 ? 65.775 14.242 58.573 1.00 15.81 ? 586 LEU A O 1 ATOM 3058 C CB . LEU A 1 396 ? 68.420 15.372 57.179 1.00 12.48 ? 586 LEU A CB 1 ATOM 3059 C CG . LEU A 1 396 ? 69.263 16.265 56.263 1.00 17.07 ? 586 LEU A CG 1 ATOM 3060 C CD1 . LEU A 1 396 ? 70.541 16.687 56.969 1.00 12.90 ? 586 LEU A CD1 1 ATOM 3061 C CD2 . LEU A 1 396 ? 69.572 15.510 54.977 1.00 12.71 ? 586 LEU A CD2 1 ATOM 3062 N N . PRO A 1 397 ? 66.429 12.755 57.017 1.00 8.38 ? 587 PRO A N 1 ATOM 3063 C CA . PRO A 1 397 ? 65.832 11.666 57.792 1.00 11.07 ? 587 PRO A CA 1 ATOM 3064 C C . PRO A 1 397 ? 66.562 11.496 59.124 1.00 12.10 ? 587 PRO A C 1 ATOM 3065 O O . PRO A 1 397 ? 67.773 11.719 59.210 1.00 5.93 ? 587 PRO A O 1 ATOM 3066 C CB . PRO A 1 397 ? 65.983 10.454 56.866 1.00 9.81 ? 587 PRO A CB 1 ATOM 3067 C CG . PRO A 1 397 ? 67.148 10.804 56.012 1.00 5.95 ? 587 PRO A CG 1 ATOM 3068 C CD . PRO A 1 397 ? 66.935 12.267 55.725 1.00 3.01 ? 587 PRO A CD 1 ATOM 3069 N N . GLY A 1 398 ? 65.815 11.118 60.160 1.00 13.62 ? 588 GLY A N 1 ATOM 3070 C CA . GLY A 1 398 ? 66.401 10.934 61.476 1.00 8.67 ? 588 GLY A CA 1 ATOM 3071 C C . GLY A 1 398 ? 66.444 12.223 62.273 1.00 13.52 ? 588 GLY A C 1 ATOM 3072 O O . GLY A 1 398 ? 66.942 12.258 63.398 1.00 17.07 ? 588 GLY A O 1 ATOM 3073 N N . THR A 1 399 ? 65.925 13.298 61.692 1.00 16.72 ? 589 THR A N 1 ATOM 3074 C CA . THR A 1 399 ? 65.912 14.583 62.377 1.00 15.77 ? 589 THR A CA 1 ATOM 3075 C C . THR A 1 399 ? 64.877 14.576 63.494 1.00 15.15 ? 589 THR A C 1 ATOM 3076 O O . THR A 1 399 ? 63.731 14.177 63.289 1.00 15.53 ? 589 THR A O 1 ATOM 3077 C CB . THR A 1 399 ? 65.576 15.715 61.408 1.00 13.53 ? 589 THR A CB 1 ATOM 3078 O OG1 . THR A 1 399 ? 66.558 15.753 60.369 1.00 14.30 ? 589 THR A OG1 1 ATOM 3079 C CG2 . THR A 1 399 ? 65.547 17.048 62.138 1.00 11.03 ? 589 THR A CG2 1 ATOM 3080 N N . LYS A 1 400 ? 65.287 15.015 64.676 1.00 13.82 ? 590 LYS A N 1 ATOM 3081 C CA . LYS A 1 400 ? 64.388 15.061 65.819 1.00 14.73 ? 590 LYS A CA 1 ATOM 3082 C C . LYS A 1 400 ? 63.246 16.032 65.516 1.00 15.49 ? 590 LYS A C 1 ATOM 3083 O O . LYS A 1 400 ? 63.424 17.249 65.550 1.00 14.28 ? 590 LYS A O 1 ATOM 3084 C CB . LYS A 1 400 ? 65.159 15.499 67.071 1.00 11.35 ? 590 LYS A CB 1 ATOM 3085 C CG . LYS A 1 400 ? 64.354 15.407 68.350 1.00 14.43 ? 590 LYS A CG 1 ATOM 3086 C CD . LYS A 1 400 ? 65.200 15.711 69.564 1.00 15.61 ? 590 LYS A CD 1 ATOM 3087 C CE . LYS A 1 400 ? 64.377 15.596 70.837 1.00 18.44 ? 590 LYS A CE 1 ATOM 3088 N NZ . LYS A 1 400 ? 65.204 15.805 72.055 1.00 19.65 ? 590 LYS A NZ 1 ATOM 3089 N N . CYS A 1 401 ? 62.077 15.477 65.210 1.00 16.84 ? 591 CYS A N 1 ATOM 3090 C CA . CYS A 1 401 ? 60.892 16.263 64.871 1.00 19.26 ? 591 CYS A CA 1 ATOM 3091 C C . CYS A 1 401 ? 60.023 16.542 66.082 1.00 18.80 ? 591 CYS A C 1 ATOM 3092 O O . CYS A 1 401 ? 59.036 17.264 65.990 1.00 17.74 ? 591 CYS A O 1 ATOM 3093 C CB . CYS A 1 401 ? 60.062 15.518 63.826 1.00 19.52 ? 591 CYS A CB 1 ATOM 3094 S SG . CYS A 1 401 ? 59.747 13.793 64.306 1.00 26.92 ? 591 CYS A SG 1 ATOM 3095 N N . ALA A 1 402 ? 60.389 15.960 67.216 1.00 21.12 ? 592 ALA A N 1 ATOM 3096 C CA . ALA A 1 402 ? 59.632 16.140 68.447 1.00 21.11 ? 592 ALA A CA 1 ATOM 3097 C C . ALA A 1 402 ? 60.326 15.371 69.551 1.00 21.83 ? 592 ALA A C 1 ATOM 3098 O O . ALA A 1 402 ? 61.101 14.452 69.283 1.00 24.16 ? 592 ALA A O 1 ATOM 3099 C CB . ALA A 1 402 ? 58.205 15.619 68.272 1.00 14.70 ? 592 ALA A CB 1 ATOM 3100 N N . ASP A 1 403 ? 60.044 15.748 70.792 1.00 20.16 ? 593 ASP A N 1 ATOM 3101 C CA . ASP A 1 403 ? 60.637 15.078 71.936 1.00 19.11 ? 593 ASP A CA 1 ATOM 3102 C C . ASP A 1 403 ? 60.308 13.588 71.844 1.00 17.04 ? 593 ASP A C 1 ATOM 3103 O O . ASP A 1 403 ? 59.140 13.205 71.775 1.00 16.47 ? 593 ASP A O 1 ATOM 3104 C CB . ASP A 1 403 ? 60.086 15.682 73.230 1.00 26.91 ? 593 ASP A CB 1 ATOM 3105 C CG . ASP A 1 403 ? 60.755 15.124 74.473 1.00 39.98 ? 593 ASP A CG 1 ATOM 3106 O OD1 . ASP A 1 403 ? 60.515 15.672 75.571 1.00 46.76 ? 593 ASP A OD1 1 ATOM 3107 O OD2 . ASP A 1 403 ? 61.514 14.138 74.357 1.00 46.04 ? 593 ASP A OD2 1 ATOM 3108 N N . GLY A 1 404 ? 61.347 12.759 71.811 1.00 15.73 ? 594 GLY A N 1 ATOM 3109 C CA . GLY A 1 404 ? 61.160 11.321 71.726 1.00 13.17 ? 594 GLY A CA 1 ATOM 3110 C C . GLY A 1 404 ? 60.801 10.809 70.343 1.00 15.49 ? 594 GLY A C 1 ATOM 3111 O O . GLY A 1 404 ? 60.599 9.606 70.155 1.00 16.04 ? 594 GLY A O 1 ATOM 3112 N N . LYS A 1 405 ? 60.729 11.710 69.367 1.00 17.53 ? 595 LYS A N 1 ATOM 3113 C CA . LYS A 1 405 ? 60.369 11.319 68.006 1.00 19.12 ? 595 LYS A CA 1 ATOM 3114 C C . LYS A 1 405 ? 61.394 11.771 66.970 1.00 17.70 ? 595 LYS A C 1 ATOM 3115 O O . LYS A 1 405 ? 62.045 12.803 67.126 1.00 17.70 ? 595 LYS A O 1 ATOM 3116 C CB . LYS A 1 405 ? 58.984 11.874 67.655 1.00 14.08 ? 595 LYS A CB 1 ATOM 3117 C CG . LYS A 1 405 ? 57.960 11.656 68.764 1.00 9.71 ? 595 LYS A CG 1 ATOM 3118 C CD . LYS A 1 405 ? 56.547 12.026 68.347 1.00 5.66 ? 595 LYS A CD 1 ATOM 3119 C CE . LYS A 1 405 ? 55.958 10.976 67.430 1.00 10.93 ? 595 LYS A CE 1 ATOM 3120 N NZ . LYS A 1 405 ? 54.527 11.232 67.136 1.00 14.58 ? 595 LYS A NZ 1 ATOM 3121 N N . VAL A 1 406 ? 61.521 10.987 65.907 1.00 16.14 ? 596 VAL A N 1 ATOM 3122 C CA . VAL A 1 406 ? 62.476 11.266 64.843 1.00 18.12 ? 596 VAL A CA 1 ATOM 3123 C C . VAL A 1 406 ? 61.775 11.133 63.481 1.00 20.36 ? 596 VAL A C 1 ATOM 3124 O O . VAL A 1 406 ? 60.708 10.525 63.390 1.00 24.93 ? 596 VAL A O 1 ATOM 3125 C CB . VAL A 1 406 ? 63.674 10.271 64.953 1.00 15.00 ? 596 VAL A CB 1 ATOM 3126 C CG1 . VAL A 1 406 ? 63.563 9.163 63.912 1.00 10.32 ? 596 VAL A CG1 1 ATOM 3127 C CG2 . VAL A 1 406 ? 64.974 11.015 64.838 1.00 16.23 ? 596 VAL A CG2 1 ATOM 3128 N N . CYS A 1 407 ? 62.358 11.701 62.428 1.00 19.91 ? 597 CYS A N 1 ATOM 3129 C CA . CYS A 1 407 ? 61.740 11.606 61.105 1.00 22.33 ? 597 CYS A CA 1 ATOM 3130 C C . CYS A 1 407 ? 62.131 10.336 60.370 1.00 20.92 ? 597 CYS A C 1 ATOM 3131 O O . CYS A 1 407 ? 63.303 9.961 60.329 1.00 19.95 ? 597 CYS A O 1 ATOM 3132 C CB . CYS A 1 407 ? 62.101 12.814 60.229 1.00 26.19 ? 597 CYS A CB 1 ATOM 3133 S SG . CYS A 1 407 ? 61.298 14.379 60.705 1.00 32.86 ? 597 CYS A SG 1 ATOM 3134 N N . SER A 1 408 ? 61.136 9.680 59.784 1.00 23.19 ? 598 SER A N 1 ATOM 3135 C CA . SER A 1 408 ? 61.363 8.452 59.035 1.00 23.81 ? 598 SER A CA 1 ATOM 3136 C C . SER A 1 408 ? 60.440 8.421 57.825 1.00 21.91 ? 598 SER A C 1 ATOM 3137 O O . SER A 1 408 ? 59.229 8.274 57.963 1.00 27.58 ? 598 SER A O 1 ATOM 3138 C CB . SER A 1 408 ? 61.098 7.237 59.922 1.00 26.09 ? 598 SER A CB 1 ATOM 3139 O OG . SER A 1 408 ? 61.411 6.040 59.236 1.00 34.61 ? 598 SER A OG 1 ATOM 3140 N N . ASN A 1 409 ? 61.022 8.572 56.640 1.00 23.32 ? 599 ASN A N 1 ATOM 3141 C CA . ASN A 1 409 ? 60.263 8.572 55.394 1.00 23.84 ? 599 ASN A CA 1 ATOM 3142 C C . ASN A 1 409 ? 59.083 9.542 55.448 1.00 22.50 ? 599 ASN A C 1 ATOM 3143 O O . ASN A 1 409 ? 57.959 9.185 55.088 1.00 19.57 ? 599 ASN A O 1 ATOM 3144 C CB . ASN A 1 409 ? 59.743 7.167 55.081 1.00 28.51 ? 599 ASN A CB 1 ATOM 3145 C CG . ASN A 1 409 ? 59.113 7.073 53.700 1.00 34.78 ? 599 ASN A CG 1 ATOM 3146 O OD1 . ASN A 1 409 ? 58.228 6.251 53.463 1.00 31.64 ? 599 ASN A OD1 1 ATOM 3147 N ND2 . ASN A 1 409 ? 59.578 7.910 52.777 1.00 39.50 ? 599 ASN A ND2 1 ATOM 3148 N N . GLY A 1 410 ? 59.345 10.764 55.903 1.00 22.27 ? 600 GLY A N 1 ATOM 3149 C CA . GLY A 1 410 ? 58.299 11.770 55.987 1.00 21.64 ? 600 GLY A CA 1 ATOM 3150 C C . GLY A 1 410 ? 57.281 11.530 57.088 1.00 20.55 ? 600 GLY A C 1 ATOM 3151 O O . GLY A 1 410 ? 56.134 11.964 56.987 1.00 23.87 ? 600 GLY A O 1 ATOM 3152 N N . HIS A 1 411 ? 57.698 10.836 58.139 1.00 18.71 ? 601 HIS A N 1 ATOM 3153 C CA . HIS A 1 411 ? 56.818 10.540 59.263 1.00 16.31 ? 601 HIS A CA 1 ATOM 3154 C C . HIS A 1 411 ? 57.525 10.822 60.584 1.00 17.49 ? 601 HIS A C 1 ATOM 3155 O O . HIS A 1 411 ? 58.636 10.339 60.816 1.00 19.48 ? 601 HIS A O 1 ATOM 3156 C CB . HIS A 1 411 ? 56.404 9.069 59.241 1.00 17.04 ? 601 HIS A CB 1 ATOM 3157 C CG . HIS A 1 411 ? 55.438 8.717 58.155 1.00 17.77 ? 601 HIS A CG 1 ATOM 3158 N ND1 . HIS A 1 411 ? 54.088 8.988 58.242 1.00 22.52 ? 601 HIS A ND1 1 ATOM 3159 C CD2 . HIS A 1 411 ? 55.618 8.080 56.974 1.00 15.64 ? 601 HIS A CD2 1 ATOM 3160 C CE1 . HIS A 1 411 ? 53.478 8.529 57.165 1.00 16.38 ? 601 HIS A CE1 1 ATOM 3161 N NE2 . HIS A 1 411 ? 54.384 7.973 56.379 1.00 18.20 ? 601 HIS A NE2 1 ATOM 3162 N N . CYS A 1 412 ? 56.891 11.608 61.445 1.00 15.07 ? 602 CYS A N 1 ATOM 3163 C CA . CYS A 1 412 ? 57.476 11.898 62.747 1.00 19.66 ? 602 CYS A CA 1 ATOM 3164 C C . CYS A 1 412 ? 57.066 10.741 63.650 1.00 21.63 ? 602 CYS A C 1 ATOM 3165 O O . CYS A 1 412 ? 55.924 10.666 64.105 1.00 23.82 ? 602 CYS A O 1 ATOM 3166 C CB . CYS A 1 412 ? 56.950 13.225 63.295 1.00 21.06 ? 602 CYS A CB 1 ATOM 3167 S SG . CYS A 1 412 ? 57.781 13.735 64.829 1.00 26.28 ? 602 CYS A SG 1 ATOM 3168 N N . VAL A 1 413 ? 58.007 9.836 63.898 1.00 23.93 ? 603 VAL A N 1 ATOM 3169 C CA . VAL A 1 413 ? 57.743 8.648 64.701 1.00 21.63 ? 603 VAL A CA 1 ATOM 3170 C C . VAL A 1 413 ? 58.623 8.508 65.942 1.00 27.54 ? 603 VAL A C 1 ATOM 3171 O O . VAL A 1 413 ? 59.675 9.141 66.049 1.00 27.41 ? 603 VAL A O 1 ATOM 3172 C CB . VAL A 1 413 ? 57.922 7.384 63.833 1.00 17.32 ? 603 VAL A CB 1 ATOM 3173 C CG1 . VAL A 1 413 ? 57.050 7.481 62.591 1.00 2.32 ? 603 VAL A CG1 1 ATOM 3174 C CG2 . VAL A 1 413 ? 59.380 7.234 63.433 1.00 12.97 ? 603 VAL A CG2 1 ATOM 3175 N N . ASP A 1 414 ? 58.182 7.664 66.875 1.00 31.77 ? 604 ASP A N 1 ATOM 3176 C CA . ASP A 1 414 ? 58.919 7.405 68.111 1.00 33.64 ? 604 ASP A CA 1 ATOM 3177 C C . ASP A 1 414 ? 60.276 6.804 67.779 1.00 31.31 ? 604 ASP A C 1 ATOM 3178 O O . ASP A 1 414 ? 60.377 5.913 66.931 1.00 22.65 ? 604 ASP A O 1 ATOM 3179 C CB . ASP A 1 414 ? 58.160 6.417 69.001 1.00 38.15 ? 604 ASP A CB 1 ATOM 3180 C CG . ASP A 1 414 ? 56.828 6.955 69.474 1.00 44.81 ? 604 ASP A CG 1 ATOM 3181 O OD1 . ASP A 1 414 ? 56.050 6.170 70.058 1.00 47.70 ? 604 ASP A OD1 1 ATOM 3182 O OD2 . ASP A 1 414 ? 56.559 8.157 69.268 1.00 48.97 ? 604 ASP A OD2 1 ATOM 3183 N N . VAL A 1 415 ? 61.311 7.286 68.459 1.00 30.45 ? 605 VAL A N 1 ATOM 3184 C CA . VAL A 1 415 ? 62.663 6.790 68.239 1.00 30.52 ? 605 VAL A CA 1 ATOM 3185 C C . VAL A 1 415 ? 62.719 5.301 68.548 1.00 35.34 ? 605 VAL A C 1 ATOM 3186 O O . VAL A 1 415 ? 63.254 4.514 67.766 1.00 38.03 ? 605 VAL A O 1 ATOM 3187 C CB . VAL A 1 415 ? 63.677 7.498 69.150 1.00 26.42 ? 605 VAL A CB 1 ATOM 3188 C CG1 . VAL A 1 415 ? 65.087 7.158 68.706 1.00 31.94 ? 605 VAL A CG1 1 ATOM 3189 C CG2 . VAL A 1 415 ? 63.450 8.995 69.122 1.00 32.90 ? 605 VAL A CG2 1 ATOM 3190 N N . ALA A 1 416 ? 62.155 4.928 69.695 1.00 39.40 ? 606 ALA A N 1 ATOM 3191 C CA . ALA A 1 416 ? 62.128 3.543 70.155 1.00 42.49 ? 606 ALA A CA 1 ATOM 3192 C C . ALA A 1 416 ? 61.598 2.558 69.115 1.00 44.29 ? 606 ALA A C 1 ATOM 3193 O O . ALA A 1 416 ? 61.965 1.382 69.122 1.00 47.15 ? 606 ALA A O 1 ATOM 3194 C CB . ALA A 1 416 ? 61.299 3.443 71.430 1.00 41.63 ? 606 ALA A CB 1 ATOM 3195 N N . THR A 1 417 ? 60.739 3.035 68.221 1.00 44.67 ? 607 THR A N 1 ATOM 3196 C CA . THR A 1 417 ? 60.172 2.178 67.185 1.00 46.56 ? 607 THR A CA 1 ATOM 3197 C C . THR A 1 417 ? 60.707 2.559 65.807 1.00 46.20 ? 607 THR A C 1 ATOM 3198 O O . THR A 1 417 ? 60.270 2.019 64.790 1.00 45.28 ? 607 THR A O 1 ATOM 3199 C CB . THR A 1 417 ? 58.649 2.303 67.150 1.00 48.95 ? 607 THR A CB 1 ATOM 3200 O OG1 . THR A 1 417 ? 58.290 3.545 66.529 1.00 51.22 ? 607 THR A OG1 1 ATOM 3201 C CG2 . THR A 1 417 ? 58.087 2.270 68.567 1.00 47.28 ? 607 THR A CG2 1 ATOM 3202 N N . ALA A 1 418 ? 61.654 3.494 65.785 1.00 44.16 ? 608 ALA A N 1 ATOM 3203 C CA . ALA A 1 418 ? 62.252 3.973 64.544 1.00 37.63 ? 608 ALA A CA 1 ATOM 3204 C C . ALA A 1 418 ? 63.341 3.050 64.009 1.00 33.75 ? 608 ALA A C 1 ATOM 3205 O O . ALA A 1 418 ? 63.433 2.822 62.803 1.00 29.24 ? 608 ALA A O 1 ATOM 3206 C CB . ALA A 1 418 ? 62.823 5.371 64.754 1.00 35.39 ? 608 ALA A CB 1 ATOM 3207 N N . TYR A 1 419 ? 64.170 2.525 64.905 1.00 30.36 ? 609 TYR A N 1 ATOM 3208 C CA . TYR A 1 419 ? 65.256 1.648 64.492 1.00 32.05 ? 609 TYR A CA 1 ATOM 3209 C C . TYR A 1 419 ? 65.214 0.322 65.241 1.00 34.88 ? 609 TYR A C 1 ATOM 3210 O O . TYR A 1 419 ? 64.343 0.179 66.125 1.00 40.71 ? 609 TYR A O 1 ATOM 3211 C CB . TYR A 1 419 ? 66.607 2.333 64.735 1.00 26.93 ? 609 TYR A CB 1 ATOM 3212 C CG . TYR A 1 419 ? 66.591 3.835 64.535 1.00 17.04 ? 609 TYR A CG 1 ATOM 3213 C CD1 . TYR A 1 419 ? 66.374 4.696 65.612 1.00 11.11 ? 609 TYR A CD1 1 ATOM 3214 C CD2 . TYR A 1 419 ? 66.777 4.396 63.265 1.00 10.97 ? 609 TYR A CD2 1 ATOM 3215 C CE1 . TYR A 1 419 ? 66.342 6.079 65.433 1.00 14.62 ? 609 TYR A CE1 1 ATOM 3216 C CE2 . TYR A 1 419 ? 66.748 5.775 63.073 1.00 4.14 ? 609 TYR A CE2 1 ATOM 3217 C CZ . TYR A 1 419 ? 66.529 6.610 64.161 1.00 15.87 ? 609 TYR A CZ 1 ATOM 3218 O OH . TYR A 1 419 ? 66.485 7.973 63.980 1.00 15.72 ? 609 TYR A OH 1 ATOM 3219 O OXT . TYR A 1 419 ? 66.057 -0.553 64.940 1.00 36.12 ? 609 TYR A OXT 1 ATOM 3220 N N . ASN B 1 5 ? 93.339 41.839 38.236 1.00 55.62 ? 195 ASN B N 1 ATOM 3221 C CA . ASN B 1 5 ? 93.069 42.398 39.592 1.00 56.69 ? 195 ASN B CA 1 ATOM 3222 C C . ASN B 1 5 ? 91.860 41.725 40.244 1.00 54.34 ? 195 ASN B C 1 ATOM 3223 O O . ASN B 1 5 ? 90.821 41.541 39.607 1.00 57.76 ? 195 ASN B O 1 ATOM 3224 C CB . ASN B 1 5 ? 92.839 43.910 39.501 1.00 57.74 ? 195 ASN B CB 1 ATOM 3225 C CG . ASN B 1 5 ? 92.387 44.509 40.816 1.00 58.76 ? 195 ASN B CG 1 ATOM 3226 O OD1 . ASN B 1 5 ? 92.981 44.253 41.864 1.00 56.61 ? 195 ASN B OD1 1 ATOM 3227 N ND2 . ASN B 1 5 ? 91.331 45.318 40.768 1.00 59.53 ? 195 ASN B ND2 1 ATOM 3228 N N . PRO B 1 6 ? 91.989 41.341 41.524 1.00 49.41 ? 196 PRO B N 1 ATOM 3229 C CA . PRO B 1 6 ? 90.916 40.681 42.277 1.00 46.32 ? 196 PRO B CA 1 ATOM 3230 C C . PRO B 1 6 ? 90.067 41.617 43.147 1.00 43.50 ? 196 PRO B C 1 ATOM 3231 O O . PRO B 1 6 ? 88.889 41.355 43.396 1.00 44.17 ? 196 PRO B O 1 ATOM 3232 C CB . PRO B 1 6 ? 91.683 39.673 43.116 1.00 47.07 ? 196 PRO B CB 1 ATOM 3233 C CG . PRO B 1 6 ? 92.892 40.476 43.512 1.00 45.46 ? 196 PRO B CG 1 ATOM 3234 C CD . PRO B 1 6 ? 93.282 41.190 42.222 1.00 47.27 ? 196 PRO B CD 1 ATOM 3235 N N . PHE B 1 7 ? 90.682 42.703 43.606 1.00 38.36 ? 197 PHE B N 1 ATOM 3236 C CA . PHE B 1 7 ? 90.036 43.690 44.468 1.00 29.91 ? 197 PHE B CA 1 ATOM 3237 C C . PHE B 1 7 ? 88.690 44.250 44.021 1.00 26.80 ? 197 PHE B C 1 ATOM 3238 O O . PHE B 1 7 ? 88.478 44.540 42.846 1.00 26.44 ? 197 PHE B O 1 ATOM 3239 C CB . PHE B 1 7 ? 90.989 44.862 44.700 1.00 24.02 ? 197 PHE B CB 1 ATOM 3240 C CG . PHE B 1 7 ? 91.794 44.749 45.956 1.00 24.27 ? 197 PHE B CG 1 ATOM 3241 C CD1 . PHE B 1 7 ? 91.222 45.042 47.188 1.00 23.16 ? 197 PHE B CD1 1 ATOM 3242 C CD2 . PHE B 1 7 ? 93.128 44.351 45.911 1.00 22.21 ? 197 PHE B CD2 1 ATOM 3243 C CE1 . PHE B 1 7 ? 91.970 44.943 48.364 1.00 27.52 ? 197 PHE B CE1 1 ATOM 3244 C CE2 . PHE B 1 7 ? 93.883 44.247 47.079 1.00 22.99 ? 197 PHE B CE2 1 ATOM 3245 C CZ . PHE B 1 7 ? 93.304 44.544 48.308 1.00 23.63 ? 197 PHE B CZ 1 ATOM 3246 N N . ARG B 1 8 ? 87.791 44.403 44.989 1.00 25.15 ? 198 ARG B N 1 ATOM 3247 C CA . ARG B 1 8 ? 86.466 44.972 44.765 1.00 24.96 ? 198 ARG B CA 1 ATOM 3248 C C . ARG B 1 8 ? 86.499 46.320 45.469 1.00 23.39 ? 198 ARG B C 1 ATOM 3249 O O . ARG B 1 8 ? 87.318 46.529 46.366 1.00 21.09 ? 198 ARG B O 1 ATOM 3250 C CB . ARG B 1 8 ? 85.380 44.100 45.397 1.00 32.18 ? 198 ARG B CB 1 ATOM 3251 C CG . ARG B 1 8 ? 85.096 42.804 44.663 1.00 42.49 ? 198 ARG B CG 1 ATOM 3252 C CD . ARG B 1 8 ? 84.425 43.067 43.326 1.00 46.13 ? 198 ARG B CD 1 ATOM 3253 N NE . ARG B 1 8 ? 84.086 41.827 42.631 1.00 50.66 ? 198 ARG B NE 1 ATOM 3254 C CZ . ARG B 1 8 ? 84.978 40.941 42.197 1.00 50.18 ? 198 ARG B CZ 1 ATOM 3255 N NH1 . ARG B 1 8 ? 86.275 41.148 42.384 1.00 47.24 ? 198 ARG B NH1 1 ATOM 3256 N NH2 . ARG B 1 8 ? 84.570 39.844 41.573 1.00 51.45 ? 198 ARG B NH2 1 ATOM 3257 N N . PHE B 1 9 ? 85.623 47.238 45.077 1.00 21.37 ? 199 PHE B N 1 ATOM 3258 C CA . PHE B 1 9 ? 85.607 48.548 45.714 1.00 16.23 ? 199 PHE B CA 1 ATOM 3259 C C . PHE B 1 9 ? 84.217 48.937 46.175 1.00 16.27 ? 199 PHE B C 1 ATOM 3260 O O . PHE B 1 9 ? 83.225 48.624 45.520 1.00 23.92 ? 199 PHE B O 1 ATOM 3261 C CB . PHE B 1 9 ? 86.130 49.621 44.758 1.00 14.96 ? 199 PHE B CB 1 ATOM 3262 C CG . PHE B 1 9 ? 87.446 49.283 44.120 1.00 14.89 ? 199 PHE B CG 1 ATOM 3263 C CD1 . PHE B 1 9 ? 87.509 48.387 43.055 1.00 16.49 ? 199 PHE B CD1 1 ATOM 3264 C CD2 . PHE B 1 9 ? 88.624 49.870 44.573 1.00 17.49 ? 199 PHE B CD2 1 ATOM 3265 C CE1 . PHE B 1 9 ? 88.728 48.083 42.447 1.00 22.79 ? 199 PHE B CE1 1 ATOM 3266 C CE2 . PHE B 1 9 ? 89.851 49.573 43.973 1.00 20.28 ? 199 PHE B CE2 1 ATOM 3267 C CZ . PHE B 1 9 ? 89.902 48.678 42.908 1.00 21.01 ? 199 PHE B CZ 1 ATOM 3268 N N . VAL B 1 10 ? 84.152 49.618 47.312 1.00 18.21 ? 200 VAL B N 1 ATOM 3269 C CA . VAL B 1 10 ? 82.882 50.080 47.860 1.00 17.45 ? 200 VAL B CA 1 ATOM 3270 C C . VAL B 1 10 ? 82.935 51.596 47.963 1.00 17.67 ? 200 VAL B C 1 ATOM 3271 O O . VAL B 1 10 ? 83.694 52.146 48.762 1.00 14.91 ? 200 VAL B O 1 ATOM 3272 C CB . VAL B 1 10 ? 82.612 49.493 49.268 1.00 21.01 ? 200 VAL B CB 1 ATOM 3273 C CG1 . VAL B 1 10 ? 81.360 50.123 49.866 1.00 20.63 ? 200 VAL B CG1 1 ATOM 3274 C CG2 . VAL B 1 10 ? 82.438 47.985 49.180 1.00 24.14 ? 200 VAL B CG2 1 ATOM 3275 N N . GLU B 1 11 ? 82.141 52.268 47.137 1.00 17.53 ? 201 GLU B N 1 ATOM 3276 C CA . GLU B 1 11 ? 82.103 53.721 47.150 1.00 20.25 ? 201 GLU B CA 1 ATOM 3277 C C . GLU B 1 11 ? 81.108 54.174 48.209 1.00 18.29 ? 201 GLU B C 1 ATOM 3278 O O . GLU B 1 11 ? 79.896 54.195 47.991 1.00 14.79 ? 201 GLU B O 1 ATOM 3279 C CB . GLU B 1 11 ? 81.746 54.241 45.757 1.00 19.19 ? 201 GLU B CB 1 ATOM 3280 C CG . GLU B 1 11 ? 82.875 54.002 44.763 1.00 21.30 ? 201 GLU B CG 1 ATOM 3281 C CD . GLU B 1 11 ? 82.501 54.321 43.333 1.00 27.42 ? 201 GLU B CD 1 ATOM 3282 O OE1 . GLU B 1 11 ? 81.594 53.649 42.792 1.00 26.17 ? 201 GLU B OE1 1 ATOM 3283 O OE2 . GLU B 1 11 ? 83.121 55.241 42.750 1.00 25.45 ? 201 GLU B OE2 1 ATOM 3284 N N . LEU B 1 12 ? 81.657 54.529 49.366 1.00 18.20 ? 202 LEU B N 1 ATOM 3285 C CA . LEU B 1 12 ? 80.884 54.947 50.527 1.00 18.89 ? 202 LEU B CA 1 ATOM 3286 C C . LEU B 1 12 ? 80.513 56.424 50.613 1.00 18.32 ? 202 LEU B C 1 ATOM 3287 O O . LEU B 1 12 ? 81.227 57.301 50.126 1.00 17.77 ? 202 LEU B O 1 ATOM 3288 C CB . LEU B 1 12 ? 81.644 54.553 51.800 1.00 16.67 ? 202 LEU B CB 1 ATOM 3289 C CG . LEU B 1 12 ? 81.102 55.006 53.157 1.00 18.57 ? 202 LEU B CG 1 ATOM 3290 C CD1 . LEU B 1 12 ? 79.737 54.381 53.412 1.00 19.82 ? 202 LEU B CD1 1 ATOM 3291 C CD2 . LEU B 1 12 ? 82.077 54.605 54.246 1.00 18.74 ? 202 LEU B CD2 1 ATOM 3292 N N . VAL B 1 13 ? 79.373 56.672 51.248 1.00 19.39 ? 203 VAL B N 1 ATOM 3293 C CA . VAL B 1 13 ? 78.866 58.013 51.484 1.00 18.47 ? 203 VAL B CA 1 ATOM 3294 C C . VAL B 1 13 ? 78.541 58.042 52.968 1.00 19.53 ? 203 VAL B C 1 ATOM 3295 O O . VAL B 1 13 ? 77.817 57.177 53.461 1.00 22.38 ? 203 VAL B O 1 ATOM 3296 C CB . VAL B 1 13 ? 77.575 58.298 50.688 1.00 15.28 ? 203 VAL B CB 1 ATOM 3297 C CG1 . VAL B 1 13 ? 76.913 59.575 51.197 1.00 14.60 ? 203 VAL B CG1 1 ATOM 3298 C CG2 . VAL B 1 13 ? 77.902 58.454 49.226 1.00 22.72 ? 203 VAL B CG2 1 ATOM 3299 N N . LEU B 1 14 ? 79.094 59.017 53.680 1.00 16.79 ? 204 LEU B N 1 ATOM 3300 C CA . LEU B 1 14 ? 78.842 59.140 55.106 1.00 16.26 ? 204 LEU B CA 1 ATOM 3301 C C . LEU B 1 14 ? 77.903 60.288 55.416 1.00 19.22 ? 204 LEU B C 1 ATOM 3302 O O . LEU B 1 14 ? 78.055 61.395 54.897 1.00 18.49 ? 204 LEU B O 1 ATOM 3303 C CB . LEU B 1 14 ? 80.149 59.338 55.874 1.00 16.93 ? 204 LEU B CB 1 ATOM 3304 C CG . LEU B 1 14 ? 80.971 58.070 56.095 1.00 22.81 ? 204 LEU B CG 1 ATOM 3305 C CD1 . LEU B 1 14 ? 82.208 58.410 56.905 1.00 15.38 ? 204 LEU B CD1 1 ATOM 3306 C CD2 . LEU B 1 14 ? 80.120 57.025 56.821 1.00 19.08 ? 204 LEU B CD2 1 ATOM 3307 N N . VAL B 1 15 ? 76.923 60.009 56.265 1.00 17.02 ? 205 VAL B N 1 ATOM 3308 C CA . VAL B 1 15 ? 75.960 61.012 56.674 1.00 16.09 ? 205 VAL B CA 1 ATOM 3309 C C . VAL B 1 15 ? 76.129 61.210 58.174 1.00 16.97 ? 205 VAL B C 1 ATOM 3310 O O . VAL B 1 15 ? 76.082 60.251 58.946 1.00 20.07 ? 205 VAL B O 1 ATOM 3311 C CB . VAL B 1 15 ? 74.520 60.559 56.365 1.00 16.73 ? 205 VAL B CB 1 ATOM 3312 C CG1 . VAL B 1 15 ? 73.528 61.637 56.779 1.00 20.61 ? 205 VAL B CG1 1 ATOM 3313 C CG2 . VAL B 1 15 ? 74.384 60.263 54.887 1.00 19.36 ? 205 VAL B CG2 1 ATOM 3314 N N . VAL B 1 16 ? 76.350 62.456 58.575 1.00 13.22 ? 206 VAL B N 1 ATOM 3315 C CA . VAL B 1 16 ? 76.533 62.806 59.979 1.00 8.93 ? 206 VAL B CA 1 ATOM 3316 C C . VAL B 1 16 ? 75.319 63.623 60.401 1.00 8.19 ? 206 VAL B C 1 ATOM 3317 O O . VAL B 1 16 ? 75.096 64.713 59.880 1.00 12.86 ? 206 VAL B O 1 ATOM 3318 C CB . VAL B 1 16 ? 77.818 63.635 60.154 1.00 6.77 ? 206 VAL B CB 1 ATOM 3319 C CG1 . VAL B 1 16 ? 77.992 64.044 61.599 1.00 6.89 ? 206 VAL B CG1 1 ATOM 3320 C CG2 . VAL B 1 16 ? 79.010 62.827 59.681 1.00 1.00 ? 206 VAL B CG2 1 ATOM 3321 N N . ASP B 1 17 ? 74.538 63.099 61.342 1.00 10.19 ? 207 ASP B N 1 ATOM 3322 C CA . ASP B 1 17 ? 73.323 63.782 61.786 1.00 13.26 ? 207 ASP B CA 1 ATOM 3323 C C . ASP B 1 17 ? 73.539 64.999 62.675 1.00 15.30 ? 207 ASP B C 1 ATOM 3324 O O . ASP B 1 17 ? 74.663 65.312 63.082 1.00 9.81 ? 207 ASP B O 1 ATOM 3325 C CB . ASP B 1 17 ? 72.373 62.792 62.479 1.00 14.05 ? 207 ASP B CB 1 ATOM 3326 C CG . ASP B 1 17 ? 72.814 62.431 63.889 1.00 21.08 ? 207 ASP B CG 1 ATOM 3327 O OD1 . ASP B 1 17 ? 74.035 62.443 64.165 1.00 27.64 ? 207 ASP B OD1 1 ATOM 3328 O OD2 . ASP B 1 17 ? 71.934 62.117 64.720 1.00 13.35 ? 207 ASP B OD2 1 ATOM 3329 N N . LYS B 1 18 ? 72.434 65.682 62.960 1.00 18.71 ? 208 LYS B N 1 ATOM 3330 C CA . LYS B 1 18 ? 72.425 66.892 63.775 1.00 20.27 ? 208 LYS B CA 1 ATOM 3331 C C . LYS B 1 18 ? 73.072 66.701 65.143 1.00 17.83 ? 208 LYS B C 1 ATOM 3332 O O . LYS B 1 18 ? 73.813 67.568 65.612 1.00 17.61 ? 208 LYS B O 1 ATOM 3333 C CB . LYS B 1 18 ? 70.982 67.380 63.942 1.00 16.86 ? 208 LYS B CB 1 ATOM 3334 C CG . LYS B 1 18 ? 70.823 68.675 64.719 1.00 19.77 ? 208 LYS B CG 1 ATOM 3335 C CD . LYS B 1 18 ? 71.500 69.849 64.024 1.00 23.15 ? 208 LYS B CD 1 ATOM 3336 C CE . LYS B 1 18 ? 71.147 71.160 64.715 1.00 22.36 ? 208 LYS B CE 1 ATOM 3337 N NZ . LYS B 1 18 ? 71.897 72.323 64.166 1.00 22.61 ? 208 LYS B NZ 1 ATOM 3338 N N . ALA B 1 19 ? 72.789 65.568 65.779 1.00 12.74 ? 209 ALA B N 1 ATOM 3339 C CA . ALA B 1 19 ? 73.343 65.283 67.096 1.00 14.75 ? 209 ALA B CA 1 ATOM 3340 C C . ALA B 1 19 ? 74.865 65.306 67.055 1.00 12.18 ? 209 ALA B C 1 ATOM 3341 O O . ALA B 1 19 ? 75.507 65.922 67.905 1.00 17.10 ? 209 ALA B O 1 ATOM 3342 C CB . ALA B 1 19 ? 72.844 63.927 67.596 1.00 10.85 ? 209 ALA B CB 1 ATOM 3343 N N . MET B 1 20 ? 75.440 64.629 66.069 1.00 11.85 ? 210 MET B N 1 ATOM 3344 C CA . MET B 1 20 ? 76.889 64.591 65.923 1.00 15.35 ? 210 MET B CA 1 ATOM 3345 C C . MET B 1 20 ? 77.459 66.000 65.813 1.00 15.39 ? 210 MET B C 1 ATOM 3346 O O . MET B 1 20 ? 78.498 66.306 66.396 1.00 14.15 ? 210 MET B O 1 ATOM 3347 C CB . MET B 1 20 ? 77.276 63.787 64.683 1.00 12.29 ? 210 MET B CB 1 ATOM 3348 C CG . MET B 1 20 ? 77.487 62.314 64.943 1.00 16.89 ? 210 MET B CG 1 ATOM 3349 S SD . MET B 1 20 ? 78.950 62.040 65.960 1.00 31.03 ? 210 MET B SD 1 ATOM 3350 C CE . MET B 1 20 ? 80.228 61.989 64.699 1.00 19.30 ? 210 MET B CE 1 ATOM 3351 N N . VAL B 1 21 ? 76.774 66.854 65.063 1.00 14.92 ? 211 VAL B N 1 ATOM 3352 C CA . VAL B 1 21 ? 77.227 68.224 64.889 1.00 15.35 ? 211 VAL B CA 1 ATOM 3353 C C . VAL B 1 21 ? 77.216 68.943 66.231 1.00 15.69 ? 211 VAL B C 1 ATOM 3354 O O . VAL B 1 21 ? 78.157 69.664 66.569 1.00 18.45 ? 211 VAL B O 1 ATOM 3355 C CB . VAL B 1 21 ? 76.327 68.989 63.896 1.00 16.16 ? 211 VAL B CB 1 ATOM 3356 C CG1 . VAL B 1 21 ? 76.837 70.410 63.726 1.00 16.01 ? 211 VAL B CG1 1 ATOM 3357 C CG2 . VAL B 1 21 ? 76.310 68.269 62.555 1.00 14.30 ? 211 VAL B CG2 1 ATOM 3358 N N . THR B 1 22 ? 76.151 68.741 66.999 1.00 7.99 ? 212 THR B N 1 ATOM 3359 C CA . THR B 1 22 ? 76.035 69.373 68.303 1.00 7.15 ? 212 THR B CA 1 ATOM 3360 C C . THR B 1 22 ? 77.098 68.824 69.249 1.00 10.39 ? 212 THR B C 1 ATOM 3361 O O . THR B 1 22 ? 77.692 69.572 70.028 1.00 12.96 ? 212 THR B O 1 ATOM 3362 C CB . THR B 1 22 ? 74.642 69.134 68.904 1.00 6.49 ? 212 THR B CB 1 ATOM 3363 O OG1 . THR B 1 22 ? 73.649 69.615 67.989 1.00 9.47 ? 212 THR B OG1 1 ATOM 3364 C CG2 . THR B 1 22 ? 74.493 69.862 70.237 1.00 1.00 ? 212 THR B CG2 1 ATOM 3365 N N . LYS B 1 23 ? 77.339 67.518 69.163 1.00 8.19 ? 213 LYS B N 1 ATOM 3366 C CA . LYS B 1 23 ? 78.334 66.859 70.002 1.00 9.92 ? 213 LYS B CA 1 ATOM 3367 C C . LYS B 1 23 ? 79.732 67.410 69.766 1.00 11.94 ? 213 LYS B C 1 ATOM 3368 O O . LYS B 1 23 ? 80.609 67.271 70.615 1.00 13.30 ? 213 LYS B O 1 ATOM 3369 C CB . LYS B 1 23 ? 78.347 65.354 69.735 1.00 7.06 ? 213 LYS B CB 1 ATOM 3370 C CG . LYS B 1 23 ? 79.346 64.593 70.593 1.00 5.06 ? 213 LYS B CG 1 ATOM 3371 C CD . LYS B 1 23 ? 79.267 63.102 70.324 1.00 7.39 ? 213 LYS B CD 1 ATOM 3372 C CE . LYS B 1 23 ? 80.126 62.302 71.288 1.00 1.00 ? 213 LYS B CE 1 ATOM 3373 N NZ . LYS B 1 23 ? 79.905 60.837 71.092 1.00 11.36 ? 213 LYS B NZ 1 ATOM 3374 N N . ASN B 1 24 ? 79.934 68.024 68.605 1.00 15.72 ? 214 ASN B N 1 ATOM 3375 C CA . ASN B 1 24 ? 81.228 68.593 68.252 1.00 14.49 ? 214 ASN B CA 1 ATOM 3376 C C . ASN B 1 24 ? 81.203 70.116 68.216 1.00 18.20 ? 214 ASN B C 1 ATOM 3377 O O . ASN B 1 24 ? 82.103 70.752 67.665 1.00 18.38 ? 214 ASN B O 1 ATOM 3378 C CB . ASN B 1 24 ? 81.692 68.032 66.910 1.00 13.51 ? 214 ASN B CB 1 ATOM 3379 C CG . ASN B 1 24 ? 82.225 66.620 67.032 1.00 17.16 ? 214 ASN B CG 1 ATOM 3380 O OD1 . ASN B 1 24 ? 83.428 66.411 67.181 1.00 17.32 ? 214 ASN B OD1 1 ATOM 3381 N ND2 . ASN B 1 24 ? 81.327 65.641 66.990 1.00 17.24 ? 214 ASN B ND2 1 ATOM 3382 N N . ASN B 1 25 ? 80.158 70.695 68.796 1.00 13.38 ? 215 ASN B N 1 ATOM 3383 C CA . ASN B 1 25 ? 80.037 72.141 68.876 1.00 14.96 ? 215 ASN B CA 1 ATOM 3384 C C . ASN B 1 25 ? 80.092 72.855 67.527 1.00 14.54 ? 215 ASN B C 1 ATOM 3385 O O . ASN B 1 25 ? 80.796 73.851 67.375 1.00 16.32 ? 215 ASN B O 1 ATOM 3386 C CB . ASN B 1 25 ? 81.140 72.670 69.794 1.00 10.48 ? 215 ASN B CB 1 ATOM 3387 C CG . ASN B 1 25 ? 81.179 71.944 71.130 1.00 9.39 ? 215 ASN B CG 1 ATOM 3388 O OD1 . ASN B 1 25 ? 82.248 71.680 71.672 1.00 11.67 ? 215 ASN B OD1 1 ATOM 3389 N ND2 . ASN B 1 25 ? 80.008 71.627 71.668 1.00 5.72 ? 215 ASN B ND2 1 ATOM 3390 N N . GLY B 1 26 ? 79.346 72.342 66.556 1.00 15.78 ? 216 GLY B N 1 ATOM 3391 C CA . GLY B 1 26 ? 79.300 72.951 65.236 1.00 13.73 ? 216 GLY B CA 1 ATOM 3392 C C . GLY B 1 26 ? 80.612 73.041 64.481 1.00 15.42 ? 216 GLY B C 1 ATOM 3393 O O . GLY B 1 26 ? 80.681 73.691 63.437 1.00 17.77 ? 216 GLY B O 1 ATOM 3394 N N . ASP B 1 27 ? 81.648 72.385 64.995 1.00 16.97 ? 217 ASP B N 1 ATOM 3395 C CA . ASP B 1 27 ? 82.965 72.406 64.366 1.00 18.99 ? 217 ASP B CA 1 ATOM 3396 C C . ASP B 1 27 ? 83.015 71.399 63.214 1.00 21.32 ? 217 ASP B C 1 ATOM 3397 O O . ASP B 1 27 ? 83.459 70.262 63.380 1.00 20.83 ? 217 ASP B O 1 ATOM 3398 C CB . ASP B 1 27 ? 84.029 72.089 65.423 1.00 21.30 ? 217 ASP B CB 1 ATOM 3399 C CG . ASP B 1 27 ? 85.448 72.338 64.934 1.00 27.72 ? 217 ASP B CG 1 ATOM 3400 O OD1 . ASP B 1 27 ? 86.351 72.435 65.794 1.00 31.08 ? 217 ASP B OD1 1 ATOM 3401 O OD2 . ASP B 1 27 ? 85.666 72.429 63.705 1.00 30.05 ? 217 ASP B OD2 1 ATOM 3402 N N . LEU B 1 28 ? 82.559 71.838 62.045 1.00 19.44 ? 218 LEU B N 1 ATOM 3403 C CA . LEU B 1 28 ? 82.512 70.997 60.853 1.00 19.17 ? 218 LEU B CA 1 ATOM 3404 C C . LEU B 1 28 ? 83.849 70.485 60.327 1.00 19.39 ? 218 LEU B C 1 ATOM 3405 O O . LEU B 1 28 ? 83.922 69.372 59.807 1.00 23.25 ? 218 LEU B O 1 ATOM 3406 C CB . LEU B 1 28 ? 81.773 71.733 59.733 1.00 17.69 ? 218 LEU B CB 1 ATOM 3407 C CG . LEU B 1 28 ? 80.246 71.625 59.712 1.00 10.75 ? 218 LEU B CG 1 ATOM 3408 C CD1 . LEU B 1 28 ? 79.671 71.896 61.083 1.00 8.40 ? 218 LEU B CD1 1 ATOM 3409 C CD2 . LEU B 1 28 ? 79.701 72.603 58.693 1.00 6.60 ? 218 LEU B CD2 1 ATOM 3410 N N . ASP B 1 29 ? 84.901 71.287 60.442 1.00 22.99 ? 219 ASP B N 1 ATOM 3411 C CA . ASP B 1 29 ? 86.209 70.854 59.966 1.00 25.73 ? 219 ASP B CA 1 ATOM 3412 C C . ASP B 1 29 ? 86.713 69.700 60.817 1.00 24.72 ? 219 ASP B C 1 ATOM 3413 O O . ASP B 1 29 ? 87.267 68.730 60.300 1.00 25.91 ? 219 ASP B O 1 ATOM 3414 C CB . ASP B 1 29 ? 87.218 72.003 60.011 1.00 31.01 ? 219 ASP B CB 1 ATOM 3415 C CG . ASP B 1 29 ? 87.014 73.000 58.890 1.00 43.26 ? 219 ASP B CG 1 ATOM 3416 O OD1 . ASP B 1 29 ? 86.993 72.576 57.712 1.00 42.23 ? 219 ASP B OD1 1 ATOM 3417 O OD2 . ASP B 1 29 ? 86.882 74.208 59.185 1.00 55.16 ? 219 ASP B OD2 1 ATOM 3418 N N . LYS B 1 30 ? 86.518 69.809 62.127 1.00 23.16 ? 220 LYS B N 1 ATOM 3419 C CA . LYS B 1 30 ? 86.952 68.764 63.040 1.00 22.59 ? 220 LYS B CA 1 ATOM 3420 C C . LYS B 1 30 ? 86.264 67.455 62.665 1.00 21.72 ? 220 LYS B C 1 ATOM 3421 O O . LYS B 1 30 ? 86.909 66.409 62.569 1.00 23.60 ? 220 LYS B O 1 ATOM 3422 C CB . LYS B 1 30 ? 86.611 69.141 64.484 1.00 19.94 ? 220 LYS B CB 1 ATOM 3423 C CG . LYS B 1 30 ? 87.094 68.126 65.503 1.00 23.03 ? 220 LYS B CG 1 ATOM 3424 C CD . LYS B 1 30 ? 86.768 68.551 66.921 1.00 31.42 ? 220 LYS B CD 1 ATOM 3425 C CE . LYS B 1 30 ? 87.300 67.541 67.927 1.00 38.31 ? 220 LYS B CE 1 ATOM 3426 N NZ . LYS B 1 30 ? 86.933 67.889 69.330 1.00 43.56 ? 220 LYS B NZ 1 ATOM 3427 N N . ILE B 1 31 ? 84.954 67.530 62.442 1.00 17.21 ? 221 ILE B N 1 ATOM 3428 C CA . ILE B 1 31 ? 84.157 66.368 62.074 1.00 15.49 ? 221 ILE B CA 1 ATOM 3429 C C . ILE B 1 31 ? 84.614 65.751 60.760 1.00 19.01 ? 221 ILE B C 1 ATOM 3430 O O . ILE B 1 31 ? 84.778 64.533 60.666 1.00 14.65 ? 221 ILE B O 1 ATOM 3431 C CB . ILE B 1 31 ? 82.655 66.733 61.940 1.00 19.16 ? 221 ILE B CB 1 ATOM 3432 C CG1 . ILE B 1 31 ? 82.090 67.136 63.307 1.00 13.51 ? 221 ILE B CG1 1 ATOM 3433 C CG2 . ILE B 1 31 ? 81.874 65.549 61.352 1.00 9.76 ? 221 ILE B CG2 1 ATOM 3434 C CD1 . ILE B 1 31 ? 80.642 67.573 63.268 1.00 6.50 ? 221 ILE B CD1 1 ATOM 3435 N N . LYS B 1 32 ? 84.812 66.591 59.748 1.00 17.43 ? 222 LYS B N 1 ATOM 3436 C CA . LYS B 1 32 ? 85.232 66.115 58.433 1.00 22.94 ? 222 LYS B CA 1 ATOM 3437 C C . LYS B 1 32 ? 86.565 65.377 58.450 1.00 23.62 ? 222 LYS B C 1 ATOM 3438 O O . LYS B 1 32 ? 86.680 64.276 57.910 1.00 23.96 ? 222 LYS B O 1 ATOM 3439 C CB . LYS B 1 32 ? 85.316 67.278 57.446 1.00 20.92 ? 222 LYS B CB 1 ATOM 3440 C CG . LYS B 1 32 ? 83.978 67.904 57.105 1.00 26.98 ? 222 LYS B CG 1 ATOM 3441 C CD . LYS B 1 32 ? 84.156 69.085 56.160 1.00 26.18 ? 222 LYS B CD 1 ATOM 3442 C CE . LYS B 1 32 ? 82.824 69.711 55.794 1.00 24.76 ? 222 LYS B CE 1 ATOM 3443 N NZ . LYS B 1 32 ? 83.013 70.874 54.886 1.00 30.98 ? 222 LYS B NZ 1 ATOM 3444 N N . THR B 1 33 ? 87.573 65.985 59.064 1.00 23.79 ? 223 THR B N 1 ATOM 3445 C CA . THR B 1 33 ? 88.888 65.366 59.122 1.00 24.26 ? 223 THR B CA 1 ATOM 3446 C C . THR B 1 33 ? 88.852 64.040 59.868 1.00 22.85 ? 223 THR B C 1 ATOM 3447 O O . THR B 1 33 ? 89.589 63.113 59.524 1.00 25.55 ? 223 THR B O 1 ATOM 3448 C CB . THR B 1 33 ? 89.915 66.292 59.794 1.00 22.99 ? 223 THR B CB 1 ATOM 3449 O OG1 . THR B 1 33 ? 89.422 66.699 61.075 1.00 31.91 ? 223 THR B OG1 1 ATOM 3450 C CG2 . THR B 1 33 ? 90.161 67.520 58.936 1.00 21.15 ? 223 THR B CG2 1 ATOM 3451 N N . ARG B 1 34 ? 87.999 63.941 60.885 1.00 16.26 ? 224 ARG B N 1 ATOM 3452 C CA . ARG B 1 34 ? 87.903 62.698 61.643 1.00 14.09 ? 224 ARG B CA 1 ATOM 3453 C C . ARG B 1 34 ? 87.306 61.597 60.766 1.00 13.52 ? 224 ARG B C 1 ATOM 3454 O O . ARG B 1 34 ? 87.814 60.477 60.739 1.00 12.33 ? 224 ARG B O 1 ATOM 3455 C CB . ARG B 1 34 ? 87.042 62.876 62.896 1.00 15.94 ? 224 ARG B CB 1 ATOM 3456 C CG . ARG B 1 34 ? 87.213 61.735 63.887 1.00 11.52 ? 224 ARG B CG 1 ATOM 3457 C CD . ARG B 1 34 ? 86.130 61.719 64.944 1.00 19.58 ? 224 ARG B CD 1 ATOM 3458 N NE . ARG B 1 34 ? 86.281 60.575 65.842 1.00 18.73 ? 224 ARG B NE 1 ATOM 3459 C CZ . ARG B 1 34 ? 85.307 60.086 66.603 1.00 11.78 ? 224 ARG B CZ 1 ATOM 3460 N NH1 . ARG B 1 34 ? 84.101 60.637 66.580 1.00 12.27 ? 224 ARG B NH1 1 ATOM 3461 N NH2 . ARG B 1 34 ? 85.538 59.040 67.381 1.00 1.70 ? 224 ARG B NH2 1 ATOM 3462 N N . MET B 1 35 ? 86.230 61.921 60.052 1.00 12.25 ? 225 MET B N 1 ATOM 3463 C CA . MET B 1 35 ? 85.578 60.970 59.158 1.00 11.98 ? 225 MET B CA 1 ATOM 3464 C C . MET B 1 35 ? 86.588 60.460 58.139 1.00 14.64 ? 225 MET B C 1 ATOM 3465 O O . MET B 1 35 ? 86.509 59.321 57.688 1.00 19.61 ? 225 MET B O 1 ATOM 3466 C CB . MET B 1 35 ? 84.414 61.633 58.424 1.00 13.96 ? 225 MET B CB 1 ATOM 3467 C CG . MET B 1 35 ? 83.346 62.208 59.340 1.00 22.42 ? 225 MET B CG 1 ATOM 3468 S SD . MET B 1 35 ? 82.639 60.977 60.446 1.00 20.10 ? 225 MET B SD 1 ATOM 3469 C CE . MET B 1 35 ? 81.378 60.301 59.396 1.00 35.98 ? 225 MET B CE 1 ATOM 3470 N N . TYR B 1 36 ? 87.534 61.315 57.768 1.00 11.52 ? 226 TYR B N 1 ATOM 3471 C CA . TYR B 1 36 ? 88.568 60.927 56.820 1.00 14.83 ? 226 TYR B CA 1 ATOM 3472 C C . TYR B 1 36 ? 89.426 59.838 57.456 1.00 10.87 ? 226 TYR B C 1 ATOM 3473 O O . TYR B 1 36 ? 89.779 58.859 56.808 1.00 13.56 ? 226 TYR B O 1 ATOM 3474 C CB . TYR B 1 36 ? 89.423 62.145 56.455 1.00 16.31 ? 226 TYR B CB 1 ATOM 3475 C CG . TYR B 1 36 ? 88.660 63.208 55.700 1.00 17.72 ? 226 TYR B CG 1 ATOM 3476 C CD1 . TYR B 1 36 ? 89.108 64.527 55.664 1.00 15.86 ? 226 TYR B CD1 1 ATOM 3477 C CD2 . TYR B 1 36 ? 87.473 62.898 55.037 1.00 16.97 ? 226 TYR B CD2 1 ATOM 3478 C CE1 . TYR B 1 36 ? 88.387 65.511 54.990 1.00 11.93 ? 226 TYR B CE1 1 ATOM 3479 C CE2 . TYR B 1 36 ? 86.750 63.871 54.362 1.00 14.05 ? 226 TYR B CE2 1 ATOM 3480 C CZ . TYR B 1 36 ? 87.209 65.172 54.344 1.00 16.58 ? 226 TYR B CZ 1 ATOM 3481 O OH . TYR B 1 36 ? 86.475 66.133 53.685 1.00 31.31 ? 226 TYR B OH 1 ATOM 3482 N N . GLU B 1 37 ? 89.750 60.021 58.732 1.00 15.15 ? 227 GLU B N 1 ATOM 3483 C CA . GLU B 1 37 ? 90.543 59.060 59.494 1.00 20.78 ? 227 GLU B CA 1 ATOM 3484 C C . GLU B 1 37 ? 89.826 57.711 59.553 1.00 21.65 ? 227 GLU B C 1 ATOM 3485 O O . GLU B 1 37 ? 90.365 56.678 59.150 1.00 19.63 ? 227 GLU B O 1 ATOM 3486 C CB . GLU B 1 37 ? 90.735 59.561 60.926 1.00 25.23 ? 227 GLU B CB 1 ATOM 3487 C CG . GLU B 1 37 ? 91.615 60.775 61.068 1.00 39.72 ? 227 GLU B CG 1 ATOM 3488 C CD . GLU B 1 37 ? 93.076 60.406 61.132 1.00 50.15 ? 227 GLU B CD 1 ATOM 3489 O OE1 . GLU B 1 37 ? 93.442 59.624 62.035 1.00 55.94 ? 227 GLU B OE1 1 ATOM 3490 O OE2 . GLU B 1 37 ? 93.856 60.896 60.285 1.00 58.06 ? 227 GLU B OE2 1 ATOM 3491 N N . ILE B 1 38 ? 88.604 57.741 60.075 1.00 14.64 ? 228 ILE B N 1 ATOM 3492 C CA . ILE B 1 38 ? 87.789 56.546 60.226 1.00 17.23 ? 228 ILE B CA 1 ATOM 3493 C C . ILE B 1 38 ? 87.621 55.752 58.931 1.00 15.63 ? 228 ILE B C 1 ATOM 3494 O O . ILE B 1 38 ? 87.905 54.556 58.894 1.00 13.80 ? 228 ILE B O 1 ATOM 3495 C CB . ILE B 1 38 ? 86.396 56.918 60.791 1.00 14.61 ? 228 ILE B CB 1 ATOM 3496 C CG1 . ILE B 1 38 ? 86.561 57.538 62.181 1.00 13.10 ? 228 ILE B CG1 1 ATOM 3497 C CG2 . ILE B 1 38 ? 85.510 55.685 60.865 1.00 17.02 ? 228 ILE B CG2 1 ATOM 3498 C CD1 . ILE B 1 38 ? 85.272 58.021 62.805 1.00 12.44 ? 228 ILE B CD1 1 ATOM 3499 N N . VAL B 1 39 ? 87.159 56.414 57.875 1.00 16.90 ? 229 VAL B N 1 ATOM 3500 C CA . VAL B 1 39 ? 86.951 55.749 56.592 1.00 16.09 ? 229 VAL B CA 1 ATOM 3501 C C . VAL B 1 39 ? 88.240 55.117 56.092 1.00 17.70 ? 229 VAL B C 1 ATOM 3502 O O . VAL B 1 39 ? 88.227 54.017 55.537 1.00 15.18 ? 229 VAL B O 1 ATOM 3503 C CB . VAL B 1 39 ? 86.444 56.734 55.518 1.00 19.22 ? 229 VAL B CB 1 ATOM 3504 C CG1 . VAL B 1 39 ? 86.241 56.007 54.197 1.00 17.61 ? 229 VAL B CG1 1 ATOM 3505 C CG2 . VAL B 1 39 ? 85.147 57.371 55.970 1.00 21.87 ? 229 VAL B CG2 1 ATOM 3506 N N . ASN B 1 40 ? 89.358 55.809 56.292 1.00 18.07 ? 230 ASN B N 1 ATOM 3507 C CA . ASN B 1 40 ? 90.635 55.278 55.844 1.00 21.20 ? 230 ASN B CA 1 ATOM 3508 C C . ASN B 1 40 ? 91.084 54.071 56.666 1.00 23.43 ? 230 ASN B C 1 ATOM 3509 O O . ASN B 1 40 ? 91.788 53.198 56.159 1.00 30.98 ? 230 ASN B O 1 ATOM 3510 C CB . ASN B 1 40 ? 91.703 56.361 55.874 1.00 21.59 ? 230 ASN B CB 1 ATOM 3511 C CG . ASN B 1 40 ? 92.875 56.026 54.983 1.00 36.01 ? 230 ASN B CG 1 ATOM 3512 O OD1 . ASN B 1 40 ? 93.877 55.461 55.434 1.00 40.04 ? 230 ASN B OD1 1 ATOM 3513 N ND2 . ASN B 1 40 ? 92.746 56.349 53.694 1.00 28.91 ? 230 ASN B ND2 1 ATOM 3514 N N . THR B 1 41 ? 90.678 54.019 57.932 1.00 20.51 ? 231 THR B N 1 ATOM 3515 C CA . THR B 1 41 ? 91.025 52.893 58.790 1.00 13.62 ? 231 THR B CA 1 ATOM 3516 C C . THR B 1 41 ? 90.139 51.708 58.397 1.00 13.58 ? 231 THR B C 1 ATOM 3517 O O . THR B 1 41 ? 90.565 50.549 58.447 1.00 13.12 ? 231 THR B O 1 ATOM 3518 C CB . THR B 1 41 ? 90.801 53.233 60.268 1.00 15.00 ? 231 THR B CB 1 ATOM 3519 O OG1 . THR B 1 41 ? 91.636 54.338 60.629 1.00 19.30 ? 231 THR B OG1 1 ATOM 3520 C CG2 . THR B 1 41 ? 91.147 52.047 61.151 1.00 19.21 ? 231 THR B CG2 1 ATOM 3521 N N . VAL B 1 42 ? 88.905 52.009 58.000 1.00 5.77 ? 232 VAL B N 1 ATOM 3522 C CA . VAL B 1 42 ? 87.973 50.978 57.568 1.00 5.86 ? 232 VAL B CA 1 ATOM 3523 C C . VAL B 1 42 ? 88.557 50.321 56.322 1.00 16.51 ? 232 VAL B C 1 ATOM 3524 O O . VAL B 1 42 ? 88.476 49.104 56.145 1.00 22.73 ? 232 VAL B O 1 ATOM 3525 C CB . VAL B 1 42 ? 86.601 51.577 57.216 1.00 5.88 ? 232 VAL B CB 1 ATOM 3526 C CG1 . VAL B 1 42 ? 85.731 50.523 56.545 1.00 1.00 ? 232 VAL B CG1 1 ATOM 3527 C CG2 . VAL B 1 42 ? 85.925 52.108 58.479 1.00 4.05 ? 232 VAL B CG2 1 ATOM 3528 N N . ASN B 1 43 ? 89.151 51.142 55.460 1.00 19.76 ? 233 ASN B N 1 ATOM 3529 C CA . ASN B 1 43 ? 89.759 50.653 54.233 1.00 16.13 ? 233 ASN B CA 1 ATOM 3530 C C . ASN B 1 43 ? 90.902 49.697 54.567 1.00 20.09 ? 233 ASN B C 1 ATOM 3531 O O . ASN B 1 43 ? 91.128 48.714 53.861 1.00 23.72 ? 233 ASN B O 1 ATOM 3532 C CB . ASN B 1 43 ? 90.290 51.826 53.406 1.00 11.95 ? 233 ASN B CB 1 ATOM 3533 C CG . ASN B 1 43 ? 90.844 51.388 52.064 1.00 10.42 ? 233 ASN B CG 1 ATOM 3534 O OD1 . ASN B 1 43 ? 90.136 50.796 51.251 1.00 13.95 ? 233 ASN B OD1 1 ATOM 3535 N ND2 . ASN B 1 43 ? 92.117 51.675 51.828 1.00 13.76 ? 233 ASN B ND2 1 ATOM 3536 N N . GLU B 1 44 ? 91.626 49.992 55.641 1.00 16.80 ? 234 GLU B N 1 ATOM 3537 C CA . GLU B 1 44 ? 92.735 49.143 56.055 1.00 19.71 ? 234 GLU B CA 1 ATOM 3538 C C . GLU B 1 44 ? 92.187 47.805 56.533 1.00 16.80 ? 234 GLU B C 1 ATOM 3539 O O . GLU B 1 44 ? 92.650 46.743 56.114 1.00 12.16 ? 234 GLU B O 1 ATOM 3540 C CB . GLU B 1 44 ? 93.531 49.807 57.185 1.00 26.25 ? 234 GLU B CB 1 ATOM 3541 C CG . GLU B 1 44 ? 94.128 51.155 56.814 1.00 37.87 ? 234 GLU B CG 1 ATOM 3542 C CD . GLU B 1 44 ? 95.011 51.728 57.907 1.00 44.81 ? 234 GLU B CD 1 ATOM 3543 O OE1 . GLU B 1 44 ? 94.518 51.907 59.042 1.00 54.48 ? 234 GLU B OE1 1 ATOM 3544 O OE2 . GLU B 1 44 ? 96.199 52.004 57.632 1.00 45.94 ? 234 GLU B OE2 1 ATOM 3545 N N . ILE B 1 45 ? 91.188 47.870 57.407 1.00 12.99 ? 235 ILE B N 1 ATOM 3546 C CA . ILE B 1 45 ? 90.564 46.676 57.953 1.00 13.53 ? 235 ILE B CA 1 ATOM 3547 C C . ILE B 1 45 ? 90.087 45.725 56.855 1.00 16.07 ? 235 ILE B C 1 ATOM 3548 O O . ILE B 1 45 ? 90.170 44.505 57.002 1.00 18.69 ? 235 ILE B O 1 ATOM 3549 C CB . ILE B 1 45 ? 89.361 47.046 58.851 1.00 14.81 ? 235 ILE B CB 1 ATOM 3550 C CG1 . ILE B 1 45 ? 89.844 47.867 60.050 1.00 10.74 ? 235 ILE B CG1 1 ATOM 3551 C CG2 . ILE B 1 45 ? 88.639 45.782 59.315 1.00 10.34 ? 235 ILE B CG2 1 ATOM 3552 C CD1 . ILE B 1 45 ? 88.722 48.377 60.938 1.00 11.03 ? 235 ILE B CD1 1 ATOM 3553 N N . TYR B 1 46 ? 89.596 46.289 55.757 1.00 14.19 ? 236 TYR B N 1 ATOM 3554 C CA . TYR B 1 46 ? 89.091 45.497 54.644 1.00 14.94 ? 236 TYR B CA 1 ATOM 3555 C C . TYR B 1 46 ? 90.134 45.044 53.626 1.00 18.49 ? 236 TYR B C 1 ATOM 3556 O O . TYR B 1 46 ? 89.790 44.398 52.634 1.00 22.44 ? 236 TYR B O 1 ATOM 3557 C CB . TYR B 1 46 ? 87.987 46.272 53.926 1.00 11.40 ? 236 TYR B CB 1 ATOM 3558 C CG . TYR B 1 46 ? 86.605 45.973 54.444 1.00 10.66 ? 236 TYR B CG 1 ATOM 3559 C CD1 . TYR B 1 46 ? 85.884 44.882 53.963 1.00 7.93 ? 236 TYR B CD1 1 ATOM 3560 C CD2 . TYR B 1 46 ? 86.022 46.770 55.430 1.00 10.24 ? 236 TYR B CD2 1 ATOM 3561 C CE1 . TYR B 1 46 ? 84.612 44.591 54.450 1.00 14.96 ? 236 TYR B CE1 1 ATOM 3562 C CE2 . TYR B 1 46 ? 84.750 46.489 55.928 1.00 10.09 ? 236 TYR B CE2 1 ATOM 3563 C CZ . TYR B 1 46 ? 84.049 45.397 55.433 1.00 14.92 ? 236 TYR B CZ 1 ATOM 3564 O OH . TYR B 1 46 ? 82.787 45.109 55.915 1.00 19.69 ? 236 TYR B OH 1 ATOM 3565 N N . ARG B 1 47 ? 91.399 45.372 53.862 1.00 20.10 ? 237 ARG B N 1 ATOM 3566 C CA . ARG B 1 47 ? 92.462 44.982 52.938 1.00 23.37 ? 237 ARG B CA 1 ATOM 3567 C C . ARG B 1 47 ? 92.568 43.458 52.854 1.00 23.38 ? 237 ARG B C 1 ATOM 3568 O O . ARG B 1 47 ? 92.627 42.882 51.767 1.00 23.42 ? 237 ARG B O 1 ATOM 3569 C CB . ARG B 1 47 ? 93.794 45.583 53.396 1.00 24.60 ? 237 ARG B CB 1 ATOM 3570 C CG . ARG B 1 47 ? 94.960 45.328 52.452 1.00 31.26 ? 237 ARG B CG 1 ATOM 3571 C CD . ARG B 1 47 ? 96.177 46.151 52.859 1.00 34.29 ? 237 ARG B CD 1 ATOM 3572 N NE . ARG B 1 47 ? 97.318 45.945 51.967 1.00 39.10 ? 237 ARG B NE 1 ATOM 3573 C CZ . ARG B 1 47 ? 98.097 44.868 51.971 1.00 38.23 ? 237 ARG B CZ 1 ATOM 3574 N NH1 . ARG B 1 47 ? 97.871 43.880 52.825 1.00 31.59 ? 237 ARG B NH1 1 ATOM 3575 N NH2 . ARG B 1 47 ? 99.106 44.778 51.116 1.00 44.06 ? 237 ARG B NH2 1 ATOM 3576 N N . TYR B 1 48 ? 92.588 42.817 54.018 1.00 23.06 ? 238 TYR B N 1 ATOM 3577 C CA . TYR B 1 48 ? 92.676 41.365 54.132 1.00 22.11 ? 238 TYR B CA 1 ATOM 3578 C C . TYR B 1 48 ? 91.523 40.701 53.388 1.00 24.78 ? 238 TYR B C 1 ATOM 3579 O O . TYR B 1 48 ? 91.625 39.554 52.956 1.00 27.03 ? 238 TYR B O 1 ATOM 3580 C CB . TYR B 1 48 ? 92.644 40.996 55.618 1.00 26.45 ? 238 TYR B CB 1 ATOM 3581 C CG . TYR B 1 48 ? 92.197 39.590 55.958 1.00 27.67 ? 238 TYR B CG 1 ATOM 3582 C CD1 . TYR B 1 48 ? 93.071 38.509 55.855 1.00 22.44 ? 238 TYR B CD1 1 ATOM 3583 C CD2 . TYR B 1 48 ? 90.905 39.352 56.431 1.00 30.94 ? 238 TYR B CD2 1 ATOM 3584 C CE1 . TYR B 1 48 ? 92.673 37.225 56.222 1.00 23.93 ? 238 TYR B CE1 1 ATOM 3585 C CE2 . TYR B 1 48 ? 90.495 38.074 56.798 1.00 31.12 ? 238 TYR B CE2 1 ATOM 3586 C CZ . TYR B 1 48 ? 91.384 37.016 56.695 1.00 30.68 ? 238 TYR B CZ 1 ATOM 3587 O OH . TYR B 1 48 ? 90.987 35.760 57.088 1.00 33.06 ? 238 TYR B OH 1 ATOM 3588 N N . MET B 1 49 ? 90.430 41.443 53.239 1.00 26.40 ? 239 MET B N 1 ATOM 3589 C CA . MET B 1 49 ? 89.229 40.959 52.564 1.00 22.47 ? 239 MET B CA 1 ATOM 3590 C C . MET B 1 49 ? 89.256 41.234 51.065 1.00 23.34 ? 239 MET B C 1 ATOM 3591 O O . MET B 1 49 ? 88.286 40.967 50.358 1.00 18.97 ? 239 MET B O 1 ATOM 3592 C CB . MET B 1 49 ? 88.004 41.637 53.172 1.00 21.23 ? 239 MET B CB 1 ATOM 3593 C CG . MET B 1 49 ? 87.803 41.343 54.642 1.00 21.46 ? 239 MET B CG 1 ATOM 3594 S SD . MET B 1 49 ? 87.032 39.746 54.892 1.00 16.84 ? 239 MET B SD 1 ATOM 3595 C CE . MET B 1 49 ? 85.306 40.222 54.893 1.00 13.48 ? 239 MET B CE 1 ATOM 3596 N N . TYR B 1 50 ? 90.370 41.767 50.580 1.00 26.09 ? 240 TYR B N 1 ATOM 3597 C CA . TYR B 1 50 ? 90.494 42.092 49.168 1.00 26.35 ? 240 TYR B CA 1 ATOM 3598 C C . TYR B 1 50 ? 89.415 43.064 48.718 1.00 25.89 ? 240 TYR B C 1 ATOM 3599 O O . TYR B 1 50 ? 88.915 42.987 47.592 1.00 25.89 ? 240 TYR B O 1 ATOM 3600 C CB . TYR B 1 50 ? 90.458 40.826 48.308 1.00 29.47 ? 240 TYR B CB 1 ATOM 3601 C CG . TYR B 1 50 ? 91.827 40.222 48.130 1.00 33.63 ? 240 TYR B CG 1 ATOM 3602 C CD1 . TYR B 1 50 ? 92.391 39.414 49.117 1.00 33.01 ? 240 TYR B CD1 1 ATOM 3603 C CD2 . TYR B 1 50 ? 92.593 40.520 47.004 1.00 36.70 ? 240 TYR B CD2 1 ATOM 3604 C CE1 . TYR B 1 50 ? 93.687 38.921 48.987 1.00 37.84 ? 240 TYR B CE1 1 ATOM 3605 C CE2 . TYR B 1 50 ? 93.889 40.034 46.865 1.00 38.84 ? 240 TYR B CE2 1 ATOM 3606 C CZ . TYR B 1 50 ? 94.431 39.237 47.858 1.00 38.68 ? 240 TYR B CZ 1 ATOM 3607 O OH . TYR B 1 50 ? 95.717 38.764 47.720 1.00 42.22 ? 240 TYR B OH 1 ATOM 3608 N N . ILE B 1 51 ? 89.063 43.979 49.615 1.00 21.93 ? 241 ILE B N 1 ATOM 3609 C CA . ILE B 1 51 ? 88.072 45.007 49.328 1.00 19.53 ? 241 ILE B CA 1 ATOM 3610 C C . ILE B 1 51 ? 88.674 46.348 49.715 1.00 19.52 ? 241 ILE B C 1 ATOM 3611 O O . ILE B 1 51 ? 89.442 46.439 50.670 1.00 23.25 ? 241 ILE B O 1 ATOM 3612 C CB . ILE B 1 51 ? 86.772 44.819 50.142 1.00 17.11 ? 241 ILE B CB 1 ATOM 3613 C CG1 . ILE B 1 51 ? 86.013 43.582 49.664 1.00 23.18 ? 241 ILE B CG1 1 ATOM 3614 C CG2 . ILE B 1 51 ? 85.879 46.041 49.982 1.00 19.10 ? 241 ILE B CG2 1 ATOM 3615 C CD1 . ILE B 1 51 ? 84.720 43.332 50.430 1.00 14.53 ? 241 ILE B CD1 1 ATOM 3616 N N . HIS B 1 52 ? 88.339 47.383 48.959 1.00 16.49 ? 242 HIS B N 1 ATOM 3617 C CA . HIS B 1 52 ? 88.825 48.720 49.252 1.00 17.84 ? 242 HIS B CA 1 ATOM 3618 C C . HIS B 1 52 ? 87.621 49.611 49.509 1.00 17.78 ? 242 HIS B C 1 ATOM 3619 O O . HIS B 1 52 ? 86.636 49.568 48.769 1.00 18.27 ? 242 HIS B O 1 ATOM 3620 C CB . HIS B 1 52 ? 89.638 49.269 48.077 1.00 16.41 ? 242 HIS B CB 1 ATOM 3621 C CG . HIS B 1 52 ? 91.045 48.761 48.025 1.00 19.05 ? 242 HIS B CG 1 ATOM 3622 N ND1 . HIS B 1 52 ? 91.799 48.774 46.871 1.00 22.31 ? 242 HIS B ND1 1 ATOM 3623 C CD2 . HIS B 1 52 ? 91.842 48.245 48.989 1.00 21.75 ? 242 HIS B CD2 1 ATOM 3624 C CE1 . HIS B 1 52 ? 93.000 48.286 47.126 1.00 21.23 ? 242 HIS B CE1 1 ATOM 3625 N NE2 . HIS B 1 52 ? 93.052 47.958 48.405 1.00 23.88 ? 242 HIS B NE2 1 ATOM 3626 N N . VAL B 1 53 ? 87.688 50.402 50.571 1.00 16.80 ? 243 VAL B N 1 ATOM 3627 C CA . VAL B 1 53 ? 86.596 51.306 50.887 1.00 20.14 ? 243 VAL B CA 1 ATOM 3628 C C . VAL B 1 53 ? 87.058 52.737 50.647 1.00 16.74 ? 243 VAL B C 1 ATOM 3629 O O . VAL B 1 53 ? 88.018 53.203 51.260 1.00 18.97 ? 243 VAL B O 1 ATOM 3630 C CB . VAL B 1 53 ? 86.130 51.143 52.350 1.00 19.55 ? 243 VAL B CB 1 ATOM 3631 C CG1 . VAL B 1 53 ? 84.993 52.109 52.644 1.00 16.13 ? 243 VAL B CG1 1 ATOM 3632 C CG2 . VAL B 1 53 ? 85.670 49.711 52.587 1.00 17.54 ? 243 VAL B CG2 1 ATOM 3633 N N . ALA B 1 54 ? 86.376 53.420 49.734 1.00 12.46 ? 244 ALA B N 1 ATOM 3634 C CA . ALA B 1 54 ? 86.706 54.794 49.392 1.00 7.59 ? 244 ALA B CA 1 ATOM 3635 C C . ALA B 1 54 ? 85.526 55.710 49.677 1.00 12.17 ? 244 ALA B C 1 ATOM 3636 O O . ALA B 1 54 ? 84.372 55.354 49.417 1.00 11.13 ? 244 ALA B O 1 ATOM 3637 C CB . ALA B 1 54 ? 87.086 54.878 47.926 1.00 10.85 ? 244 ALA B CB 1 ATOM 3638 N N . LEU B 1 55 ? 85.819 56.892 50.210 1.00 16.69 ? 245 LEU B N 1 ATOM 3639 C CA . LEU B 1 55 ? 84.781 57.864 50.533 1.00 18.58 ? 245 LEU B CA 1 ATOM 3640 C C . LEU B 1 55 ? 84.541 58.776 49.333 1.00 23.15 ? 245 LEU B C 1 ATOM 3641 O O . LEU B 1 55 ? 85.452 59.481 48.888 1.00 24.86 ? 245 LEU B O 1 ATOM 3642 C CB . LEU B 1 55 ? 85.206 58.698 51.741 1.00 20.89 ? 245 LEU B CB 1 ATOM 3643 C CG . LEU B 1 55 ? 84.096 59.464 52.463 1.00 26.18 ? 245 LEU B CG 1 ATOM 3644 C CD1 . LEU B 1 55 ? 83.181 58.479 53.176 1.00 25.74 ? 245 LEU B CD1 1 ATOM 3645 C CD2 . LEU B 1 55 ? 84.708 60.428 53.465 1.00 31.15 ? 245 LEU B CD2 1 ATOM 3646 N N . VAL B 1 56 ? 83.317 58.757 48.810 1.00 22.42 ? 246 VAL B N 1 ATOM 3647 C CA . VAL B 1 56 ? 82.967 59.583 47.658 1.00 23.89 ? 246 VAL B CA 1 ATOM 3648 C C . VAL B 1 56 ? 81.860 60.586 47.977 1.00 26.00 ? 246 VAL B C 1 ATOM 3649 O O . VAL B 1 56 ? 81.384 61.294 47.090 1.00 29.67 ? 246 VAL B O 1 ATOM 3650 C CB . VAL B 1 56 ? 82.498 58.720 46.465 1.00 23.95 ? 246 VAL B CB 1 ATOM 3651 C CG1 . VAL B 1 56 ? 83.535 57.657 46.151 1.00 25.61 ? 246 VAL B CG1 1 ATOM 3652 C CG2 . VAL B 1 56 ? 81.146 58.090 46.773 1.00 18.72 ? 246 VAL B CG2 1 ATOM 3653 N N . GLY B 1 57 ? 81.448 60.639 49.240 1.00 23.23 ? 247 GLY B N 1 ATOM 3654 C CA . GLY B 1 57 ? 80.398 61.560 49.630 1.00 18.57 ? 247 GLY B CA 1 ATOM 3655 C C . GLY B 1 57 ? 80.271 61.685 51.135 1.00 21.51 ? 247 GLY B C 1 ATOM 3656 O O . GLY B 1 57 ? 80.277 60.682 51.847 1.00 20.78 ? 247 GLY B O 1 ATOM 3657 N N . LEU B 1 58 ? 80.152 62.919 51.616 1.00 17.22 ? 248 LEU B N 1 ATOM 3658 C CA . LEU B 1 58 ? 80.031 63.186 53.042 1.00 14.39 ? 248 LEU B CA 1 ATOM 3659 C C . LEU B 1 58 ? 79.056 64.331 53.297 1.00 18.57 ? 248 LEU B C 1 ATOM 3660 O O . LEU B 1 58 ? 79.391 65.502 53.125 1.00 26.19 ? 248 LEU B O 1 ATOM 3661 C CB . LEU B 1 58 ? 81.405 63.528 53.623 1.00 13.24 ? 248 LEU B CB 1 ATOM 3662 C CG . LEU B 1 58 ? 81.475 64.058 55.059 1.00 14.50 ? 248 LEU B CG 1 ATOM 3663 C CD1 . LEU B 1 58 ? 80.792 63.101 56.015 1.00 12.46 ? 248 LEU B CD1 1 ATOM 3664 C CD2 . LEU B 1 58 ? 82.932 64.251 55.446 1.00 15.20 ? 248 LEU B CD2 1 ATOM 3665 N N . GLU B 1 59 ? 77.846 63.981 53.710 1.00 22.35 ? 249 GLU B N 1 ATOM 3666 C CA . GLU B 1 59 ? 76.802 64.960 53.988 1.00 21.66 ? 249 GLU B CA 1 ATOM 3667 C C . GLU B 1 59 ? 76.667 65.164 55.498 1.00 19.91 ? 249 GLU B C 1 ATOM 3668 O O . GLU B 1 59 ? 76.719 64.205 56.268 1.00 21.14 ? 249 GLU B O 1 ATOM 3669 C CB . GLU B 1 59 ? 75.487 64.472 53.376 1.00 20.66 ? 249 GLU B CB 1 ATOM 3670 C CG . GLU B 1 59 ? 74.262 65.294 53.721 1.00 31.23 ? 249 GLU B CG 1 ATOM 3671 C CD . GLU B 1 59 ? 73.074 64.953 52.831 1.00 35.78 ? 249 GLU B CD 1 ATOM 3672 O OE1 . GLU B 1 59 ? 71.927 65.243 53.228 1.00 31.98 ? 249 GLU B OE1 1 ATOM 3673 O OE2 . GLU B 1 59 ? 73.292 64.405 51.726 1.00 39.52 ? 249 GLU B OE2 1 ATOM 3674 N N . ILE B 1 60 ? 76.495 66.412 55.920 1.00 15.67 ? 250 ILE B N 1 ATOM 3675 C CA . ILE B 1 60 ? 76.390 66.711 57.342 1.00 15.05 ? 250 ILE B CA 1 ATOM 3676 C C . ILE B 1 60 ? 75.186 67.583 57.663 1.00 14.80 ? 250 ILE B C 1 ATOM 3677 O O . ILE B 1 60 ? 75.154 68.764 57.333 1.00 18.20 ? 250 ILE B O 1 ATOM 3678 C CB . ILE B 1 60 ? 77.674 67.409 57.834 1.00 18.69 ? 250 ILE B CB 1 ATOM 3679 C CG1 . ILE B 1 60 ? 78.888 66.551 57.463 1.00 14.09 ? 250 ILE B CG1 1 ATOM 3680 C CG2 . ILE B 1 60 ? 77.612 67.632 59.345 1.00 20.85 ? 250 ILE B CG2 1 ATOM 3681 C CD1 . ILE B 1 60 ? 80.210 67.215 57.715 1.00 11.74 ? 250 ILE B CD1 1 ATOM 3682 N N . TRP B 1 61 ? 74.200 66.992 58.325 1.00 15.75 ? 251 TRP B N 1 ATOM 3683 C CA . TRP B 1 61 ? 72.982 67.704 58.685 1.00 15.42 ? 251 TRP B CA 1 ATOM 3684 C C . TRP B 1 61 ? 73.191 68.719 59.805 1.00 13.07 ? 251 TRP B C 1 ATOM 3685 O O . TRP B 1 61 ? 72.681 68.555 60.912 1.00 7.92 ? 251 TRP B O 1 ATOM 3686 C CB . TRP B 1 61 ? 71.900 66.696 59.079 1.00 16.41 ? 251 TRP B CB 1 ATOM 3687 C CG . TRP B 1 61 ? 71.581 65.722 57.983 1.00 15.78 ? 251 TRP B CG 1 ATOM 3688 C CD1 . TRP B 1 61 ? 71.834 65.880 56.651 1.00 18.11 ? 251 TRP B CD1 1 ATOM 3689 C CD2 . TRP B 1 61 ? 70.910 64.464 58.117 1.00 18.97 ? 251 TRP B CD2 1 ATOM 3690 N NE1 . TRP B 1 61 ? 71.364 64.801 55.946 1.00 21.03 ? 251 TRP B NE1 1 ATOM 3691 C CE2 . TRP B 1 61 ? 70.793 63.915 56.820 1.00 22.45 ? 251 TRP B CE2 1 ATOM 3692 C CE3 . TRP B 1 61 ? 70.397 63.746 59.204 1.00 17.14 ? 251 TRP B CE3 1 ATOM 3693 C CZ2 . TRP B 1 61 ? 70.178 62.679 56.580 1.00 19.98 ? 251 TRP B CZ2 1 ATOM 3694 C CZ3 . TRP B 1 61 ? 69.784 62.515 58.964 1.00 18.86 ? 251 TRP B CZ3 1 ATOM 3695 C CH2 . TRP B 1 61 ? 69.683 61.996 57.662 1.00 15.98 ? 251 TRP B CH2 1 ATOM 3696 N N . SER B 1 62 ? 73.935 69.778 59.504 1.00 14.74 ? 252 SER B N 1 ATOM 3697 C CA . SER B 1 62 ? 74.214 70.814 60.489 1.00 20.33 ? 252 SER B CA 1 ATOM 3698 C C . SER B 1 62 ? 72.990 71.669 60.817 1.00 21.61 ? 252 SER B C 1 ATOM 3699 O O . SER B 1 62 ? 72.927 72.282 61.883 1.00 22.86 ? 252 SER B O 1 ATOM 3700 C CB . SER B 1 62 ? 75.365 71.703 60.010 1.00 17.44 ? 252 SER B CB 1 ATOM 3701 O OG . SER B 1 62 ? 75.077 72.279 58.749 1.00 26.94 ? 252 SER B OG 1 ATOM 3702 N N . ASN B 1 63 ? 72.018 71.712 59.912 1.00 21.03 ? 253 ASN B N 1 ATOM 3703 C CA . ASN B 1 63 ? 70.811 72.493 60.159 1.00 24.75 ? 253 ASN B CA 1 ATOM 3704 C C . ASN B 1 63 ? 69.752 71.636 60.833 1.00 25.15 ? 253 ASN B C 1 ATOM 3705 O O . ASN B 1 63 ? 69.469 71.798 62.020 1.00 24.81 ? 253 ASN B O 1 ATOM 3706 C CB . ASN B 1 63 ? 70.250 73.057 58.852 1.00 32.50 ? 253 ASN B CB 1 ATOM 3707 C CG . ASN B 1 63 ? 71.193 74.040 58.189 1.00 44.42 ? 253 ASN B CG 1 ATOM 3708 O OD1 . ASN B 1 63 ? 71.635 75.010 58.811 1.00 49.36 ? 253 ASN B OD1 1 ATOM 3709 N ND2 . ASN B 1 63 ? 71.505 73.799 56.919 1.00 46.36 ? 253 ASN B ND2 1 ATOM 3710 N N . GLU B 1 64 ? 69.171 70.720 60.067 1.00 26.65 ? 254 GLU B N 1 ATOM 3711 C CA . GLU B 1 64 ? 68.138 69.836 60.584 1.00 29.12 ? 254 GLU B CA 1 ATOM 3712 C C . GLU B 1 64 ? 68.329 68.441 59.997 1.00 27.12 ? 254 GLU B C 1 ATOM 3713 O O . GLU B 1 64 ? 68.906 68.294 58.920 1.00 23.63 ? 254 GLU B O 1 ATOM 3714 C CB . GLU B 1 64 ? 66.758 70.376 60.200 1.00 32.38 ? 254 GLU B CB 1 ATOM 3715 C CG . GLU B 1 64 ? 65.712 70.271 61.304 1.00 50.07 ? 254 GLU B CG 1 ATOM 3716 C CD . GLU B 1 64 ? 65.998 71.190 62.489 1.00 55.92 ? 254 GLU B CD 1 ATOM 3717 O OE1 . GLU B 1 64 ? 67.078 71.058 63.108 1.00 57.13 ? 254 GLU B OE1 1 ATOM 3718 O OE2 . GLU B 1 64 ? 65.139 72.044 62.803 1.00 56.33 ? 254 GLU B OE2 1 ATOM 3719 N N . ASP B 1 65 ? 67.867 67.417 60.711 1.00 29.33 ? 255 ASP B N 1 ATOM 3720 C CA . ASP B 1 65 ? 67.978 66.047 60.217 1.00 30.66 ? 255 ASP B CA 1 ATOM 3721 C C . ASP B 1 65 ? 66.992 65.883 59.069 1.00 30.94 ? 255 ASP B C 1 ATOM 3722 O O . ASP B 1 65 ? 65.866 66.377 59.134 1.00 29.17 ? 255 ASP B O 1 ATOM 3723 C CB . ASP B 1 65 ? 67.624 65.024 61.302 1.00 34.43 ? 255 ASP B CB 1 ATOM 3724 C CG . ASP B 1 65 ? 68.680 64.912 62.379 1.00 35.90 ? 255 ASP B CG 1 ATOM 3725 O OD1 . ASP B 1 65 ? 69.878 64.815 62.039 1.00 40.86 ? 255 ASP B OD1 1 ATOM 3726 O OD2 . ASP B 1 65 ? 68.307 64.901 63.570 1.00 38.03 ? 255 ASP B OD2 1 ATOM 3727 N N . LYS B 1 66 ? 67.410 65.188 58.019 1.00 29.57 ? 256 LYS B N 1 ATOM 3728 C CA . LYS B 1 66 ? 66.535 64.974 56.879 1.00 24.68 ? 256 LYS B CA 1 ATOM 3729 C C . LYS B 1 66 ? 65.615 63.774 57.110 1.00 23.53 ? 256 LYS B C 1 ATOM 3730 O O . LYS B 1 66 ? 64.759 63.466 56.281 1.00 22.65 ? 256 LYS B O 1 ATOM 3731 C CB . LYS B 1 66 ? 67.369 64.805 55.612 1.00 21.24 ? 256 LYS B CB 1 ATOM 3732 C CG . LYS B 1 66 ? 68.129 66.068 55.261 1.00 22.88 ? 256 LYS B CG 1 ATOM 3733 C CD . LYS B 1 66 ? 68.922 65.926 53.976 1.00 30.22 ? 256 LYS B CD 1 ATOM 3734 C CE . LYS B 1 66 ? 69.604 67.240 53.609 1.00 28.67 ? 256 LYS B CE 1 ATOM 3735 N NZ . LYS B 1 66 ? 70.344 67.145 52.321 1.00 29.77 ? 256 LYS B NZ 1 ATOM 3736 N N . ILE B 1 67 ? 65.801 63.102 58.244 1.00 21.05 ? 257 ILE B N 1 ATOM 3737 C CA . ILE B 1 67 ? 64.961 61.968 58.621 1.00 20.17 ? 257 ILE B CA 1 ATOM 3738 C C . ILE B 1 67 ? 64.762 62.039 60.132 1.00 22.87 ? 257 ILE B C 1 ATOM 3739 O O . ILE B 1 67 ? 65.425 62.820 60.817 1.00 25.57 ? 257 ILE B O 1 ATOM 3740 C CB . ILE B 1 67 ? 65.604 60.598 58.276 1.00 18.59 ? 257 ILE B CB 1 ATOM 3741 C CG1 . ILE B 1 67 ? 66.594 60.188 59.365 1.00 17.77 ? 257 ILE B CG1 1 ATOM 3742 C CG2 . ILE B 1 67 ? 66.303 60.671 56.924 1.00 21.90 ? 257 ILE B CG2 1 ATOM 3743 C CD1 . ILE B 1 67 ? 67.076 58.766 59.233 1.00 22.67 ? 257 ILE B CD1 1 ATOM 3744 N N . THR B 1 68 ? 63.850 61.229 60.650 1.00 21.01 ? 258 THR B N 1 ATOM 3745 C CA . THR B 1 68 ? 63.585 61.213 62.082 1.00 20.98 ? 258 THR B CA 1 ATOM 3746 C C . THR B 1 68 ? 64.510 60.199 62.756 1.00 18.63 ? 258 THR B C 1 ATOM 3747 O O . THR B 1 68 ? 64.223 59.002 62.763 1.00 19.27 ? 258 THR B O 1 ATOM 3748 C CB . THR B 1 68 ? 62.105 60.834 62.368 1.00 20.17 ? 258 THR B CB 1 ATOM 3749 O OG1 . THR B 1 68 ? 61.236 61.789 61.745 1.00 23.94 ? 258 THR B OG1 1 ATOM 3750 C CG2 . THR B 1 68 ? 61.830 60.816 63.863 1.00 19.32 ? 258 THR B CG2 1 ATOM 3751 N N . VAL B 1 69 ? 65.623 60.678 63.312 1.00 14.78 ? 259 VAL B N 1 ATOM 3752 C CA . VAL B 1 69 ? 66.579 59.794 63.985 1.00 14.47 ? 259 VAL B CA 1 ATOM 3753 C C . VAL B 1 69 ? 66.115 59.471 65.400 1.00 16.29 ? 259 VAL B C 1 ATOM 3754 O O . VAL B 1 69 ? 66.099 60.343 66.267 1.00 18.84 ? 259 VAL B O 1 ATOM 3755 C CB . VAL B 1 69 ? 67.981 60.428 64.076 1.00 7.43 ? 259 VAL B CB 1 ATOM 3756 C CG1 . VAL B 1 69 ? 68.935 59.461 64.749 1.00 10.53 ? 259 VAL B CG1 1 ATOM 3757 C CG2 . VAL B 1 69 ? 68.489 60.790 62.685 1.00 8.72 ? 259 VAL B CG2 1 ATOM 3758 N N . LYS B 1 70 ? 65.744 58.216 65.632 1.00 13.46 ? 260 LYS B N 1 ATOM 3759 C CA . LYS B 1 70 ? 65.264 57.799 66.946 1.00 12.12 ? 260 LYS B CA 1 ATOM 3760 C C . LYS B 1 70 ? 66.234 56.802 67.562 1.00 9.56 ? 260 LYS B C 1 ATOM 3761 O O . LYS B 1 70 ? 66.972 56.123 66.851 1.00 14.25 ? 260 LYS B O 1 ATOM 3762 C CB . LYS B 1 70 ? 63.867 57.163 66.824 1.00 5.66 ? 260 LYS B CB 1 ATOM 3763 C CG . LYS B 1 70 ? 62.898 57.961 65.953 1.00 7.56 ? 260 LYS B CG 1 ATOM 3764 C CD . LYS B 1 70 ? 61.530 57.291 65.793 1.00 4.49 ? 260 LYS B CD 1 ATOM 3765 C CE . LYS B 1 70 ? 60.650 57.542 66.994 1.00 16.28 ? 260 LYS B CE 1 ATOM 3766 N NZ . LYS B 1 70 ? 60.490 59.008 67.238 1.00 21.79 ? 260 LYS B NZ 1 ATOM 3767 N N . PRO B 1 71 ? 66.263 56.715 68.898 1.00 9.69 ? 261 PRO B N 1 ATOM 3768 C CA . PRO B 1 71 ? 67.181 55.761 69.526 1.00 16.28 ? 261 PRO B CA 1 ATOM 3769 C C . PRO B 1 71 ? 66.826 54.302 69.235 1.00 21.88 ? 261 PRO B C 1 ATOM 3770 O O . PRO B 1 71 ? 67.513 53.389 69.694 1.00 23.21 ? 261 PRO B O 1 ATOM 3771 C CB . PRO B 1 71 ? 67.100 56.119 71.013 1.00 11.04 ? 261 PRO B CB 1 ATOM 3772 C CG . PRO B 1 71 ? 65.779 56.810 71.153 1.00 1.00 ? 261 PRO B CG 1 ATOM 3773 C CD . PRO B 1 71 ? 65.682 57.623 69.900 1.00 6.95 ? 261 PRO B CD 1 ATOM 3774 N N . GLU B 1 72 ? 65.754 54.092 68.471 1.00 24.44 ? 262 GLU B N 1 ATOM 3775 C CA . GLU B 1 72 ? 65.320 52.746 68.092 1.00 23.62 ? 262 GLU B CA 1 ATOM 3776 C C . GLU B 1 72 ? 65.990 52.433 66.749 1.00 21.62 ? 262 GLU B C 1 ATOM 3777 O O . GLU B 1 72 ? 65.491 52.828 65.690 1.00 22.64 ? 262 GLU B O 1 ATOM 3778 C CB . GLU B 1 72 ? 63.795 52.701 67.937 1.00 26.11 ? 262 GLU B CB 1 ATOM 3779 C CG . GLU B 1 72 ? 63.207 51.294 67.909 1.00 34.35 ? 262 GLU B CG 1 ATOM 3780 C CD . GLU B 1 72 ? 61.781 51.250 67.361 1.00 47.63 ? 262 GLU B CD 1 ATOM 3781 O OE1 . GLU B 1 72 ? 60.925 52.049 67.809 1.00 43.31 ? 262 GLU B OE1 1 ATOM 3782 O OE2 . GLU B 1 72 ? 61.515 50.403 66.478 1.00 53.11 ? 262 GLU B OE2 1 ATOM 3783 N N . ALA B 1 73 ? 67.122 51.733 66.801 1.00 15.70 ? 263 ALA B N 1 ATOM 3784 C CA . ALA B 1 73 ? 67.893 51.388 65.603 1.00 11.22 ? 263 ALA B CA 1 ATOM 3785 C C . ALA B 1 73 ? 67.050 50.970 64.402 1.00 11.76 ? 263 ALA B C 1 ATOM 3786 O O . ALA B 1 73 ? 67.152 51.562 63.324 1.00 10.11 ? 263 ALA B O 1 ATOM 3787 C CB . ALA B 1 73 ? 68.906 50.292 65.932 1.00 6.06 ? 263 ALA B CB 1 ATOM 3788 N N . GLY B 1 74 ? 66.224 49.946 64.593 1.00 17.96 ? 264 GLY B N 1 ATOM 3789 C CA . GLY B 1 74 ? 65.375 49.457 63.521 1.00 13.03 ? 264 GLY B CA 1 ATOM 3790 C C . GLY B 1 74 ? 64.565 50.549 62.853 1.00 11.35 ? 264 GLY B C 1 ATOM 3791 O O . GLY B 1 74 ? 64.452 50.584 61.631 1.00 11.19 ? 264 GLY B O 1 ATOM 3792 N N . TYR B 1 75 ? 63.990 51.443 63.646 1.00 12.37 ? 265 TYR B N 1 ATOM 3793 C CA . TYR B 1 75 ? 63.203 52.524 63.077 1.00 16.62 ? 265 TYR B CA 1 ATOM 3794 C C . TYR B 1 75 ? 64.100 53.407 62.211 1.00 19.81 ? 265 TYR B C 1 ATOM 3795 O O . TYR B 1 75 ? 63.829 53.627 61.027 1.00 17.12 ? 265 TYR B O 1 ATOM 3796 C CB . TYR B 1 75 ? 62.569 53.379 64.178 1.00 15.26 ? 265 TYR B CB 1 ATOM 3797 C CG . TYR B 1 75 ? 61.727 54.508 63.627 1.00 15.35 ? 265 TYR B CG 1 ATOM 3798 C CD1 . TYR B 1 75 ? 60.336 54.417 63.604 1.00 18.57 ? 265 TYR B CD1 1 ATOM 3799 C CD2 . TYR B 1 75 ? 62.325 55.631 63.053 1.00 12.17 ? 265 TYR B CD2 1 ATOM 3800 C CE1 . TYR B 1 75 ? 59.559 55.412 63.016 1.00 18.42 ? 265 TYR B CE1 1 ATOM 3801 C CE2 . TYR B 1 75 ? 61.560 56.627 62.463 1.00 19.08 ? 265 TYR B CE2 1 ATOM 3802 C CZ . TYR B 1 75 ? 60.178 56.512 62.444 1.00 21.06 ? 265 TYR B CZ 1 ATOM 3803 O OH . TYR B 1 75 ? 59.419 57.483 61.828 1.00 27.32 ? 265 TYR B OH 1 ATOM 3804 N N . THR B 1 76 ? 65.168 53.912 62.819 1.00 20.49 ? 266 THR B N 1 ATOM 3805 C CA . THR B 1 76 ? 66.106 54.785 62.130 1.00 16.63 ? 266 THR B CA 1 ATOM 3806 C C . THR B 1 76 ? 66.713 54.147 60.886 1.00 16.80 ? 266 THR B C 1 ATOM 3807 O O . THR B 1 76 ? 66.809 54.794 59.843 1.00 21.67 ? 266 THR B O 1 ATOM 3808 C CB . THR B 1 76 ? 67.241 55.223 63.074 1.00 14.40 ? 266 THR B CB 1 ATOM 3809 O OG1 . THR B 1 76 ? 66.685 55.946 64.181 1.00 7.09 ? 266 THR B OG1 1 ATOM 3810 C CG2 . THR B 1 76 ? 68.237 56.112 62.338 1.00 10.41 ? 266 THR B CG2 1 ATOM 3811 N N . LEU B 1 77 ? 67.124 52.886 60.988 1.00 12.72 ? 267 LEU B N 1 ATOM 3812 C CA . LEU B 1 77 ? 67.716 52.203 59.842 1.00 12.67 ? 267 LEU B CA 1 ATOM 3813 C C . LEU B 1 77 ? 66.771 52.211 58.645 1.00 15.25 ? 267 LEU B C 1 ATOM 3814 O O . LEU B 1 77 ? 67.168 52.545 57.528 1.00 15.42 ? 267 LEU B O 1 ATOM 3815 C CB . LEU B 1 77 ? 68.069 50.760 60.199 1.00 14.49 ? 267 LEU B CB 1 ATOM 3816 C CG . LEU B 1 77 ? 68.536 49.907 59.013 1.00 16.89 ? 267 LEU B CG 1 ATOM 3817 C CD1 . LEU B 1 77 ? 69.737 50.558 58.352 1.00 9.76 ? 267 LEU B CD1 1 ATOM 3818 C CD2 . LEU B 1 77 ? 68.873 48.503 59.490 1.00 17.82 ? 267 LEU B CD2 1 ATOM 3819 N N . ASN B 1 78 ? 65.518 51.841 58.884 1.00 17.63 ? 268 ASN B N 1 ATOM 3820 C CA . ASN B 1 78 ? 64.520 51.818 57.826 1.00 14.69 ? 268 ASN B CA 1 ATOM 3821 C C . ASN B 1 78 ? 64.243 53.215 57.279 1.00 12.66 ? 268 ASN B C 1 ATOM 3822 O O . ASN B 1 78 ? 64.155 53.396 56.068 1.00 14.94 ? 268 ASN B O 1 ATOM 3823 C CB . ASN B 1 78 ? 63.224 51.186 58.335 1.00 14.72 ? 268 ASN B CB 1 ATOM 3824 C CG . ASN B 1 78 ? 62.059 51.432 57.405 1.00 21.40 ? 268 ASN B CG 1 ATOM 3825 O OD1 . ASN B 1 78 ? 61.333 52.419 57.549 1.00 18.99 ? 268 ASN B OD1 1 ATOM 3826 N ND2 . ASN B 1 78 ? 61.883 50.545 56.427 1.00 19.50 ? 268 ASN B ND2 1 ATOM 3827 N N . ALA B 1 79 ? 64.102 54.197 58.167 1.00 14.13 ? 269 ALA B N 1 ATOM 3828 C CA . ALA B 1 79 ? 63.846 55.576 57.747 1.00 14.77 ? 269 ALA B CA 1 ATOM 3829 C C . ALA B 1 79 ? 65.024 56.065 56.918 1.00 19.49 ? 269 ALA B C 1 ATOM 3830 O O . ALA B 1 79 ? 64.846 56.637 55.843 1.00 24.19 ? 269 ALA B O 1 ATOM 3831 C CB . ALA B 1 79 ? 63.653 56.481 58.963 1.00 8.37 ? 269 ALA B CB 1 ATOM 3832 N N . PHE B 1 80 ? 66.230 55.832 57.426 1.00 20.92 ? 270 PHE B N 1 ATOM 3833 C CA . PHE B 1 80 ? 67.445 56.234 56.732 1.00 19.71 ? 270 PHE B CA 1 ATOM 3834 C C . PHE B 1 80 ? 67.515 55.546 55.374 1.00 21.57 ? 270 PHE B C 1 ATOM 3835 O O . PHE B 1 80 ? 68.024 56.111 54.407 1.00 23.34 ? 270 PHE B O 1 ATOM 3836 C CB . PHE B 1 80 ? 68.680 55.855 57.552 1.00 16.37 ? 270 PHE B CB 1 ATOM 3837 C CG . PHE B 1 80 ? 69.976 56.197 56.879 1.00 9.29 ? 270 PHE B CG 1 ATOM 3838 C CD1 . PHE B 1 80 ? 70.322 57.522 56.641 1.00 8.39 ? 270 PHE B CD1 1 ATOM 3839 C CD2 . PHE B 1 80 ? 70.843 55.194 56.462 1.00 12.44 ? 270 PHE B CD2 1 ATOM 3840 C CE1 . PHE B 1 80 ? 71.512 57.843 55.996 1.00 5.91 ? 270 PHE B CE1 1 ATOM 3841 C CE2 . PHE B 1 80 ? 72.041 55.506 55.814 1.00 4.96 ? 270 PHE B CE2 1 ATOM 3842 C CZ . PHE B 1 80 ? 72.373 56.830 55.582 1.00 1.23 ? 270 PHE B CZ 1 ATOM 3843 N N . GLY B 1 81 ? 67.011 54.317 55.317 1.00 17.98 ? 271 GLY B N 1 ATOM 3844 C CA . GLY B 1 81 ? 67.021 53.572 54.074 1.00 16.64 ? 271 GLY B CA 1 ATOM 3845 C C . GLY B 1 81 ? 66.114 54.205 53.040 1.00 19.00 ? 271 GLY B C 1 ATOM 3846 O O . GLY B 1 81 ? 66.511 54.386 51.889 1.00 17.23 ? 271 GLY B O 1 ATOM 3847 N N . GLU B 1 82 ? 64.892 54.537 53.450 1.00 20.24 ? 272 GLU B N 1 ATOM 3848 C CA . GLU B 1 82 ? 63.920 55.160 52.559 1.00 23.42 ? 272 GLU B CA 1 ATOM 3849 C C . GLU B 1 82 ? 64.511 56.441 51.996 1.00 23.90 ? 272 GLU B C 1 ATOM 3850 O O . GLU B 1 82 ? 64.501 56.669 50.784 1.00 23.43 ? 272 GLU B O 1 ATOM 3851 C CB . GLU B 1 82 ? 62.634 55.501 53.319 1.00 28.18 ? 272 GLU B CB 1 ATOM 3852 C CG . GLU B 1 82 ? 61.767 54.311 53.712 1.00 37.75 ? 272 GLU B CG 1 ATOM 3853 C CD . GLU B 1 82 ? 61.054 53.680 52.526 1.00 41.88 ? 272 GLU B CD 1 ATOM 3854 O OE1 . GLU B 1 82 ? 61.675 52.867 51.810 1.00 41.12 ? 272 GLU B OE1 1 ATOM 3855 O OE2 . GLU B 1 82 ? 59.869 54.008 52.306 1.00 45.43 ? 272 GLU B OE2 1 ATOM 3856 N N . TRP B 1 83 ? 65.028 57.275 52.891 1.00 22.40 ? 273 TRP B N 1 ATOM 3857 C CA . TRP B 1 83 ? 65.625 58.543 52.500 1.00 21.45 ? 273 TRP B CA 1 ATOM 3858 C C . TRP B 1 83 ? 66.772 58.365 51.510 1.00 22.42 ? 273 TRP B C 1 ATOM 3859 O O . TRP B 1 83 ? 66.978 59.204 50.634 1.00 25.28 ? 273 TRP B O 1 ATOM 3860 C CB . TRP B 1 83 ? 66.140 59.290 53.731 1.00 19.55 ? 273 TRP B CB 1 ATOM 3861 C CG . TRP B 1 83 ? 66.876 60.537 53.377 1.00 20.36 ? 273 TRP B CG 1 ATOM 3862 C CD1 . TRP B 1 83 ? 66.335 61.720 52.967 1.00 18.39 ? 273 TRP B CD1 1 ATOM 3863 C CD2 . TRP B 1 83 ? 68.297 60.701 53.312 1.00 21.52 ? 273 TRP B CD2 1 ATOM 3864 N NE1 . TRP B 1 83 ? 67.331 62.610 52.644 1.00 18.95 ? 273 TRP B NE1 1 ATOM 3865 C CE2 . TRP B 1 83 ? 68.546 62.010 52.847 1.00 18.46 ? 273 TRP B CE2 1 ATOM 3866 C CE3 . TRP B 1 83 ? 69.386 59.865 53.596 1.00 18.97 ? 273 TRP B CE3 1 ATOM 3867 C CZ2 . TRP B 1 83 ? 69.837 62.504 52.662 1.00 12.70 ? 273 TRP B CZ2 1 ATOM 3868 C CZ3 . TRP B 1 83 ? 70.670 60.356 53.410 1.00 16.12 ? 273 TRP B CZ3 1 ATOM 3869 C CH2 . TRP B 1 83 ? 70.883 61.665 52.946 1.00 18.68 ? 273 TRP B CH2 1 ATOM 3870 N N . ARG B 1 84 ? 67.515 57.272 51.648 1.00 23.22 ? 274 ARG B N 1 ATOM 3871 C CA . ARG B 1 84 ? 68.650 57.017 50.770 1.00 24.87 ? 274 ARG B CA 1 ATOM 3872 C C . ARG B 1 84 ? 68.244 56.769 49.323 1.00 28.72 ? 274 ARG B C 1 ATOM 3873 O O . ARG B 1 84 ? 68.926 57.208 48.396 1.00 30.71 ? 274 ARG B O 1 ATOM 3874 C CB . ARG B 1 84 ? 69.459 55.819 51.271 1.00 20.94 ? 274 ARG B CB 1 ATOM 3875 C CG . ARG B 1 84 ? 70.843 55.744 50.657 1.00 24.30 ? 274 ARG B CG 1 ATOM 3876 C CD . ARG B 1 84 ? 71.099 54.417 49.977 1.00 26.83 ? 274 ARG B CD 1 ATOM 3877 N NE . ARG B 1 84 ? 72.357 54.433 49.236 1.00 25.02 ? 274 ARG B NE 1 ATOM 3878 C CZ . ARG B 1 84 ? 72.757 53.458 48.428 1.00 27.17 ? 274 ARG B CZ 1 ATOM 3879 N NH1 . ARG B 1 84 ? 71.997 52.385 48.261 1.00 31.60 ? 274 ARG B NH1 1 ATOM 3880 N NH2 . ARG B 1 84 ? 73.904 53.561 47.771 1.00 30.24 ? 274 ARG B NH2 1 ATOM 3881 N N . LYS B 1 85 ? 67.134 56.068 49.124 1.00 28.02 ? 275 LYS B N 1 ATOM 3882 C CA . LYS B 1 85 ? 66.689 55.767 47.773 1.00 31.21 ? 275 LYS B CA 1 ATOM 3883 C C . LYS B 1 85 ? 65.867 56.887 47.149 1.00 32.15 ? 275 LYS B C 1 ATOM 3884 O O . LYS B 1 85 ? 66.029 57.197 45.970 1.00 34.03 ? 275 LYS B O 1 ATOM 3885 C CB . LYS B 1 85 ? 65.889 54.462 47.761 1.00 31.01 ? 275 LYS B CB 1 ATOM 3886 C CG . LYS B 1 85 ? 64.462 54.579 48.263 1.00 32.64 ? 275 LYS B CG 1 ATOM 3887 C CD . LYS B 1 85 ? 63.797 53.210 48.348 1.00 37.39 ? 275 LYS B CD 1 ATOM 3888 C CE . LYS B 1 85 ? 64.064 52.376 47.096 1.00 41.15 ? 275 LYS B CE 1 ATOM 3889 N NZ . LYS B 1 85 ? 63.730 53.104 45.839 1.00 43.01 ? 275 LYS B NZ 1 ATOM 3890 N N . THR B 1 86 ? 64.996 57.502 47.941 1.00 32.28 ? 276 THR B N 1 ATOM 3891 C CA . THR B 1 86 ? 64.148 58.576 47.439 1.00 30.39 ? 276 THR B CA 1 ATOM 3892 C C . THR B 1 86 ? 64.744 59.968 47.636 1.00 30.22 ? 276 THR B C 1 ATOM 3893 O O . THR B 1 86 ? 64.007 60.951 47.704 1.00 35.66 ? 276 THR B O 1 ATOM 3894 C CB . THR B 1 86 ? 62.758 58.546 48.112 1.00 28.94 ? 276 THR B CB 1 ATOM 3895 O OG1 . THR B 1 86 ? 62.868 59.000 49.466 1.00 29.95 ? 276 THR B OG1 1 ATOM 3896 C CG2 . THR B 1 86 ? 62.196 57.128 48.111 1.00 31.05 ? 276 THR B CG2 1 ATOM 3897 N N . ASP B 1 87 ? 66.068 60.061 47.729 1.00 28.20 ? 277 ASP B N 1 ATOM 3898 C CA . ASP B 1 87 ? 66.708 61.359 47.914 1.00 26.41 ? 277 ASP B CA 1 ATOM 3899 C C . ASP B 1 87 ? 68.188 61.380 47.547 1.00 28.06 ? 277 ASP B C 1 ATOM 3900 O O . ASP B 1 87 ? 68.548 61.829 46.462 1.00 34.44 ? 277 ASP B O 1 ATOM 3901 C CB . ASP B 1 87 ? 66.539 61.838 49.358 1.00 26.81 ? 277 ASP B CB 1 ATOM 3902 C CG . ASP B 1 87 ? 66.917 63.303 49.537 1.00 28.01 ? 277 ASP B CG 1 ATOM 3903 O OD1 . ASP B 1 87 ? 68.069 63.676 49.229 1.00 21.87 ? 277 ASP B OD1 1 ATOM 3904 O OD2 . ASP B 1 87 ? 66.055 64.086 49.990 1.00 34.49 ? 277 ASP B OD2 1 ATOM 3905 N N . LEU B 1 88 ? 69.044 60.902 48.449 1.00 25.21 ? 278 LEU B N 1 ATOM 3906 C CA . LEU B 1 88 ? 70.486 60.897 48.209 1.00 26.21 ? 278 LEU B CA 1 ATOM 3907 C C . LEU B 1 88 ? 70.865 60.223 46.893 1.00 27.09 ? 278 LEU B C 1 ATOM 3908 O O . LEU B 1 88 ? 71.415 60.859 45.991 1.00 25.76 ? 278 LEU B O 1 ATOM 3909 C CB . LEU B 1 88 ? 71.217 60.195 49.358 1.00 26.65 ? 278 LEU B CB 1 ATOM 3910 C CG . LEU B 1 88 ? 72.748 60.278 49.299 1.00 21.89 ? 278 LEU B CG 1 ATOM 3911 C CD1 . LEU B 1 88 ? 73.175 61.725 49.505 1.00 19.60 ? 278 LEU B CD1 1 ATOM 3912 C CD2 . LEU B 1 88 ? 73.371 59.392 50.362 1.00 18.05 ? 278 LEU B CD2 1 ATOM 3913 N N . LEU B 1 89 ? 70.568 58.931 46.800 1.00 29.12 ? 279 LEU B N 1 ATOM 3914 C CA . LEU B 1 89 ? 70.861 58.129 45.615 1.00 28.11 ? 279 LEU B CA 1 ATOM 3915 C C . LEU B 1 89 ? 70.374 58.825 44.345 1.00 29.53 ? 279 LEU B C 1 ATOM 3916 O O . LEU B 1 89 ? 70.880 58.572 43.248 1.00 28.89 ? 279 LEU B O 1 ATOM 3917 C CB . LEU B 1 89 ? 70.190 56.762 45.753 1.00 25.96 ? 279 LEU B CB 1 ATOM 3918 C CG . LEU B 1 89 ? 70.680 55.618 44.868 1.00 23.38 ? 279 LEU B CG 1 ATOM 3919 C CD1 . LEU B 1 89 ? 72.181 55.426 45.048 1.00 17.60 ? 279 LEU B CD1 1 ATOM 3920 C CD2 . LEU B 1 89 ? 69.927 54.345 45.243 1.00 22.52 ? 279 LEU B CD2 1 ATOM 3921 N N . THR B 1 90 ? 69.388 59.701 44.508 1.00 31.24 ? 280 THR B N 1 ATOM 3922 C CA . THR B 1 90 ? 68.813 60.462 43.402 1.00 32.26 ? 280 THR B CA 1 ATOM 3923 C C . THR B 1 90 ? 69.780 61.523 42.881 1.00 32.10 ? 280 THR B C 1 ATOM 3924 O O . THR B 1 90 ? 69.915 61.718 41.673 1.00 32.25 ? 280 THR B O 1 ATOM 3925 C CB . THR B 1 90 ? 67.509 61.164 43.844 1.00 31.06 ? 280 THR B CB 1 ATOM 3926 O OG1 . THR B 1 90 ? 66.462 60.193 43.959 1.00 36.78 ? 280 THR B OG1 1 ATOM 3927 C CG2 . THR B 1 90 ? 67.106 62.245 42.850 1.00 26.02 ? 280 THR B CG2 1 ATOM 3928 N N . ARG B 1 91 ? 70.452 62.204 43.798 1.00 30.54 ? 281 ARG B N 1 ATOM 3929 C CA . ARG B 1 91 ? 71.383 63.251 43.420 1.00 32.98 ? 281 ARG B CA 1 ATOM 3930 C C . ARG B 1 91 ? 72.846 62.849 43.543 1.00 31.02 ? 281 ARG B C 1 ATOM 3931 O O . ARG B 1 91 ? 73.735 63.613 43.167 1.00 33.27 ? 281 ARG B O 1 ATOM 3932 C CB . ARG B 1 91 ? 71.102 64.504 44.255 1.00 36.14 ? 281 ARG B CB 1 ATOM 3933 C CG . ARG B 1 91 ? 70.902 64.235 45.733 1.00 39.39 ? 281 ARG B CG 1 ATOM 3934 C CD . ARG B 1 91 ? 70.341 65.460 46.445 1.00 37.89 ? 281 ARG B CD 1 ATOM 3935 N NE . ARG B 1 91 ? 70.264 65.260 47.889 1.00 38.97 ? 281 ARG B NE 1 ATOM 3936 C CZ . ARG B 1 91 ? 71.316 65.003 48.663 1.00 38.75 ? 281 ARG B CZ 1 ATOM 3937 N NH1 . ARG B 1 91 ? 72.529 64.916 48.132 1.00 34.97 ? 281 ARG B NH1 1 ATOM 3938 N NH2 . ARG B 1 91 ? 71.156 64.833 49.968 1.00 38.73 ? 281 ARG B NH2 1 ATOM 3939 N N . LYS B 1 92 ? 73.100 61.652 44.058 1.00 27.12 ? 282 LYS B N 1 ATOM 3940 C CA . LYS B 1 92 ? 74.474 61.195 44.209 1.00 29.61 ? 282 LYS B CA 1 ATOM 3941 C C . LYS B 1 92 ? 74.621 59.698 43.977 1.00 31.43 ? 282 LYS B C 1 ATOM 3942 O O . LYS B 1 92 ? 73.947 58.885 44.610 1.00 32.20 ? 282 LYS B O 1 ATOM 3943 C CB . LYS B 1 92 ? 75.003 61.541 45.602 1.00 28.28 ? 282 LYS B CB 1 ATOM 3944 C CG . LYS B 1 92 ? 76.476 61.936 45.624 1.00 31.93 ? 282 LYS B CG 1 ATOM 3945 C CD . LYS B 1 92 ? 77.357 60.945 44.875 1.00 21.48 ? 282 LYS B CD 1 ATOM 3946 C CE . LYS B 1 92 ? 78.779 61.477 44.755 1.00 28.92 ? 282 LYS B CE 1 ATOM 3947 N NZ . LYS B 1 92 ? 79.643 60.618 43.889 1.00 31.28 ? 282 LYS B NZ 1 ATOM 3948 N N . LYS B 1 93 ? 75.519 59.342 43.069 1.00 32.48 ? 283 LYS B N 1 ATOM 3949 C CA . LYS B 1 93 ? 75.767 57.948 42.751 1.00 31.03 ? 283 LYS B CA 1 ATOM 3950 C C . LYS B 1 93 ? 76.821 57.393 43.707 1.00 28.71 ? 283 LYS B C 1 ATOM 3951 O O . LYS B 1 93 ? 77.926 57.927 43.806 1.00 30.13 ? 283 LYS B O 1 ATOM 3952 C CB . LYS B 1 93 ? 76.252 57.810 41.301 1.00 32.61 ? 283 LYS B CB 1 ATOM 3953 C CG . LYS B 1 93 ? 75.380 58.521 40.261 1.00 37.79 ? 283 LYS B CG 1 ATOM 3954 C CD . LYS B 1 93 ? 75.613 60.034 40.265 1.00 42.75 ? 283 LYS B CD 1 ATOM 3955 C CE . LYS B 1 93 ? 74.760 60.754 39.222 1.00 44.84 ? 283 LYS B CE 1 ATOM 3956 N NZ . LYS B 1 93 ? 73.296 60.699 39.521 1.00 46.81 ? 283 LYS B NZ 1 ATOM 3957 N N . HIS B 1 94 ? 76.465 56.331 44.420 1.00 24.77 ? 284 HIS B N 1 ATOM 3958 C CA . HIS B 1 94 ? 77.375 55.690 45.360 1.00 20.65 ? 284 HIS B CA 1 ATOM 3959 C C . HIS B 1 94 ? 76.919 54.259 45.567 1.00 17.77 ? 284 HIS B C 1 ATOM 3960 O O . HIS B 1 94 ? 75.806 53.900 45.191 1.00 17.84 ? 284 HIS B O 1 ATOM 3961 C CB . HIS B 1 94 ? 77.390 56.434 46.697 1.00 21.99 ? 284 HIS B CB 1 ATOM 3962 C CG . HIS B 1 94 ? 76.053 56.505 47.367 1.00 21.54 ? 284 HIS B CG 1 ATOM 3963 N ND1 . HIS B 1 94 ? 74.957 57.102 46.783 1.00 22.51 ? 284 HIS B ND1 1 ATOM 3964 C CD2 . HIS B 1 94 ? 75.636 56.052 48.573 1.00 23.98 ? 284 HIS B CD2 1 ATOM 3965 C CE1 . HIS B 1 94 ? 73.922 57.012 47.599 1.00 26.09 ? 284 HIS B CE1 1 ATOM 3966 N NE2 . HIS B 1 94 ? 74.307 56.380 48.692 1.00 22.61 ? 284 HIS B NE2 1 ATOM 3967 N N . ASP B 1 95 ? 77.771 53.448 46.178 1.00 21.83 ? 285 ASP B N 1 ATOM 3968 C CA . ASP B 1 95 ? 77.454 52.041 46.403 1.00 23.23 ? 285 ASP B CA 1 ATOM 3969 C C . ASP B 1 95 ? 76.800 51.738 47.749 1.00 22.99 ? 285 ASP B C 1 ATOM 3970 O O . ASP B 1 95 ? 75.810 51.011 47.815 1.00 23.87 ? 285 ASP B O 1 ATOM 3971 C CB . ASP B 1 95 ? 78.731 51.208 46.268 1.00 20.77 ? 285 ASP B CB 1 ATOM 3972 C CG . ASP B 1 95 ? 79.409 51.400 44.928 1.00 23.35 ? 285 ASP B CG 1 ATOM 3973 O OD1 . ASP B 1 95 ? 80.640 51.209 44.845 1.00 29.92 ? 285 ASP B OD1 1 ATOM 3974 O OD2 . ASP B 1 95 ? 78.710 51.735 43.952 1.00 27.61 ? 285 ASP B OD2 1 ATOM 3975 N N . ASN B 1 96 ? 77.351 52.303 48.816 1.00 23.75 ? 286 ASN B N 1 ATOM 3976 C CA . ASN B 1 96 ? 76.849 52.046 50.160 1.00 22.53 ? 286 ASN B CA 1 ATOM 3977 C C . ASN B 1 96 ? 76.799 53.323 50.998 1.00 20.03 ? 286 ASN B C 1 ATOM 3978 O O . ASN B 1 96 ? 77.634 54.213 50.835 1.00 16.91 ? 286 ASN B O 1 ATOM 3979 C CB . ASN B 1 96 ? 77.757 50.993 50.813 1.00 24.73 ? 286 ASN B CB 1 ATOM 3980 C CG . ASN B 1 96 ? 77.302 50.591 52.194 1.00 26.17 ? 286 ASN B CG 1 ATOM 3981 O OD1 . ASN B 1 96 ? 77.577 51.277 53.179 1.00 30.88 ? 286 ASN B OD1 1 ATOM 3982 N ND2 . ASN B 1 96 ? 76.598 49.471 52.276 1.00 24.92 ? 286 ASN B ND2 1 ATOM 3983 N N . ALA B 1 97 ? 75.818 53.408 51.894 1.00 18.15 ? 287 ALA B N 1 ATOM 3984 C CA . ALA B 1 97 ? 75.664 54.584 52.745 1.00 19.15 ? 287 ALA B CA 1 ATOM 3985 C C . ALA B 1 97 ? 75.532 54.246 54.229 1.00 18.98 ? 287 ALA B C 1 ATOM 3986 O O . ALA B 1 97 ? 74.736 53.387 54.618 1.00 14.78 ? 287 ALA B O 1 ATOM 3987 C CB . ALA B 1 97 ? 74.460 55.394 52.290 1.00 24.99 ? 287 ALA B CB 1 ATOM 3988 N N . GLN B 1 98 ? 76.312 54.946 55.049 1.00 16.47 ? 288 GLN B N 1 ATOM 3989 C CA . GLN B 1 98 ? 76.317 54.746 56.493 1.00 15.61 ? 288 GLN B CA 1 ATOM 3990 C C . GLN B 1 98 ? 76.015 56.051 57.229 1.00 18.29 ? 288 GLN B C 1 ATOM 3991 O O . GLN B 1 98 ? 76.592 57.095 56.922 1.00 23.05 ? 288 GLN B O 1 ATOM 3992 C CB . GLN B 1 98 ? 77.678 54.208 56.934 1.00 15.84 ? 288 GLN B CB 1 ATOM 3993 C CG . GLN B 1 98 ? 78.045 52.875 56.304 1.00 26.08 ? 288 GLN B CG 1 ATOM 3994 C CD . GLN B 1 98 ? 77.184 51.734 56.811 1.00 32.48 ? 288 GLN B CD 1 ATOM 3995 O OE1 . GLN B 1 98 ? 77.107 50.669 56.192 1.00 33.84 ? 288 GLN B OE1 1 ATOM 3996 N NE2 . GLN B 1 98 ? 76.537 51.948 57.948 1.00 31.77 ? 288 GLN B NE2 1 ATOM 3997 N N . LEU B 1 99 ? 75.106 55.980 58.198 1.00 18.12 ? 289 LEU B N 1 ATOM 3998 C CA . LEU B 1 99 ? 74.708 57.138 58.994 1.00 15.23 ? 289 LEU B CA 1 ATOM 3999 C C . LEU B 1 99 ? 75.364 57.095 60.370 1.00 18.41 ? 289 LEU B C 1 ATOM 4000 O O . LEU B 1 99 ? 75.155 56.153 61.136 1.00 13.99 ? 289 LEU B O 1 ATOM 4001 C CB . LEU B 1 99 ? 73.189 57.160 59.174 1.00 14.58 ? 289 LEU B CB 1 ATOM 4002 C CG . LEU B 1 99 ? 72.629 58.200 60.152 1.00 18.83 ? 289 LEU B CG 1 ATOM 4003 C CD1 . LEU B 1 99 ? 72.777 59.600 59.566 1.00 16.62 ? 289 LEU B CD1 1 ATOM 4004 C CD2 . LEU B 1 99 ? 71.167 57.897 60.435 1.00 19.30 ? 289 LEU B CD2 1 ATOM 4005 N N . LEU B 1 100 ? 76.151 58.121 60.681 1.00 18.12 ? 290 LEU B N 1 ATOM 4006 C CA . LEU B 1 100 ? 76.829 58.200 61.969 1.00 16.07 ? 290 LEU B CA 1 ATOM 4007 C C . LEU B 1 100 ? 76.048 59.162 62.860 1.00 14.70 ? 290 LEU B C 1 ATOM 4008 O O . LEU B 1 100 ? 75.981 60.358 62.582 1.00 16.17 ? 290 LEU B O 1 ATOM 4009 C CB . LEU B 1 100 ? 78.267 58.700 61.776 1.00 16.34 ? 290 LEU B CB 1 ATOM 4010 C CG . LEU B 1 100 ? 79.210 58.623 62.982 1.00 18.95 ? 290 LEU B CG 1 ATOM 4011 C CD1 . LEU B 1 100 ? 79.380 57.179 63.409 1.00 17.90 ? 290 LEU B CD1 1 ATOM 4012 C CD2 . LEU B 1 100 ? 80.559 59.217 62.622 1.00 18.15 ? 290 LEU B CD2 1 ATOM 4013 N N . THR B 1 101 ? 75.450 58.636 63.924 1.00 13.14 ? 291 THR B N 1 ATOM 4014 C CA . THR B 1 101 ? 74.667 59.457 64.842 1.00 14.40 ? 291 THR B CA 1 ATOM 4015 C C . THR B 1 101 ? 75.246 59.484 66.254 1.00 13.34 ? 291 THR B C 1 ATOM 4016 O O . THR B 1 101 ? 75.803 58.493 66.726 1.00 14.64 ? 291 THR B O 1 ATOM 4017 C CB . THR B 1 101 ? 73.204 58.961 64.931 1.00 15.85 ? 291 THR B CB 1 ATOM 4018 O OG1 . THR B 1 101 ? 72.512 59.684 65.959 1.00 18.53 ? 291 THR B OG1 1 ATOM 4019 C CG2 . THR B 1 101 ? 73.163 57.478 65.251 1.00 10.10 ? 291 THR B CG2 1 ATOM 4020 N N . ALA B 1 102 ? 75.099 60.622 66.927 1.00 10.41 ? 292 ALA B N 1 ATOM 4021 C CA . ALA B 1 102 ? 75.608 60.774 68.285 1.00 10.10 ? 292 ALA B CA 1 ATOM 4022 C C . ALA B 1 102 ? 74.568 60.350 69.316 1.00 14.05 ? 292 ALA B C 1 ATOM 4023 O O . ALA B 1 102 ? 74.848 60.318 70.516 1.00 14.91 ? 292 ALA B O 1 ATOM 4024 C CB . ALA B 1 102 ? 76.026 62.216 68.528 1.00 4.09 ? 292 ALA B CB 1 ATOM 4025 N N . ILE B 1 103 ? 73.368 60.024 68.848 1.00 15.19 ? 293 ILE B N 1 ATOM 4026 C CA . ILE B 1 103 ? 72.302 59.596 69.744 1.00 16.37 ? 293 ILE B CA 1 ATOM 4027 C C . ILE B 1 103 ? 72.616 58.240 70.368 1.00 16.11 ? 293 ILE B C 1 ATOM 4028 O O . ILE B 1 103 ? 73.108 57.332 69.700 1.00 18.63 ? 293 ILE B O 1 ATOM 4029 C CB . ILE B 1 103 ? 70.950 59.507 69.005 1.00 17.28 ? 293 ILE B CB 1 ATOM 4030 C CG1 . ILE B 1 103 ? 70.508 60.906 68.571 1.00 21.28 ? 293 ILE B CG1 1 ATOM 4031 C CG2 . ILE B 1 103 ? 69.896 58.884 69.908 1.00 17.38 ? 293 ILE B CG2 1 ATOM 4032 C CD1 . ILE B 1 103 ? 69.191 60.934 67.837 1.00 24.77 ? 293 ILE B CD1 1 ATOM 4033 N N . ASP B 1 104 ? 72.334 58.111 71.657 1.00 16.40 ? 294 ASP B N 1 ATOM 4034 C CA . ASP B 1 104 ? 72.583 56.863 72.358 1.00 18.10 ? 294 ASP B CA 1 ATOM 4035 C C . ASP B 1 104 ? 71.488 55.877 71.964 1.00 20.15 ? 294 ASP B C 1 ATOM 4036 O O . ASP B 1 104 ? 70.416 55.849 72.572 1.00 21.55 ? 294 ASP B O 1 ATOM 4037 C CB . ASP B 1 104 ? 72.580 57.112 73.869 1.00 20.58 ? 294 ASP B CB 1 ATOM 4038 C CG . ASP B 1 104 ? 73.020 55.899 74.662 1.00 28.16 ? 294 ASP B CG 1 ATOM 4039 O OD1 . ASP B 1 104 ? 73.886 55.144 74.167 1.00 29.52 ? 294 ASP B OD1 1 ATOM 4040 O OD2 . ASP B 1 104 ? 72.511 55.711 75.788 1.00 31.71 ? 294 ASP B OD2 1 ATOM 4041 N N . LEU B 1 105 ? 71.761 55.086 70.929 1.00 16.93 ? 295 LEU B N 1 ATOM 4042 C CA . LEU B 1 105 ? 70.803 54.102 70.433 1.00 17.67 ? 295 LEU B CA 1 ATOM 4043 C C . LEU B 1 105 ? 70.370 53.142 71.526 1.00 17.55 ? 295 LEU B C 1 ATOM 4044 O O . LEU B 1 105 ? 71.082 52.937 72.506 1.00 21.94 ? 295 LEU B O 1 ATOM 4045 C CB . LEU B 1 105 ? 71.405 53.304 69.273 1.00 13.72 ? 295 LEU B CB 1 ATOM 4046 C CG . LEU B 1 105 ? 71.736 54.048 67.977 1.00 16.57 ? 295 LEU B CG 1 ATOM 4047 C CD1 . LEU B 1 105 ? 72.447 53.102 67.024 1.00 17.09 ? 295 LEU B CD1 1 ATOM 4048 C CD2 . LEU B 1 105 ? 70.465 54.588 67.339 1.00 14.46 ? 295 LEU B CD2 1 ATOM 4049 N N . ASP B 1 106 ? 69.195 52.553 71.348 1.00 21.23 ? 296 ASP B N 1 ATOM 4050 C CA . ASP B 1 106 ? 68.659 51.607 72.313 1.00 24.41 ? 296 ASP B CA 1 ATOM 4051 C C . ASP B 1 106 ? 69.163 50.199 72.052 1.00 25.26 ? 296 ASP B C 1 ATOM 4052 O O . ASP B 1 106 ? 69.124 49.713 70.921 1.00 28.57 ? 296 ASP B O 1 ATOM 4053 C CB . ASP B 1 106 ? 67.128 51.604 72.266 1.00 29.91 ? 296 ASP B CB 1 ATOM 4054 C CG . ASP B 1 106 ? 66.513 52.811 72.956 1.00 36.09 ? 296 ASP B CG 1 ATOM 4055 O OD1 . ASP B 1 106 ? 65.304 53.052 72.755 1.00 39.29 ? 296 ASP B OD1 1 ATOM 4056 O OD2 . ASP B 1 106 ? 67.227 53.511 73.704 1.00 39.63 ? 296 ASP B OD2 1 ATOM 4057 N N . ARG B 1 107 ? 69.648 49.559 73.111 1.00 26.31 ? 297 ARG B N 1 ATOM 4058 C CA . ARG B 1 107 ? 70.133 48.182 73.061 1.00 23.97 ? 297 ARG B CA 1 ATOM 4059 C C . ARG B 1 107 ? 71.363 47.887 72.215 1.00 21.17 ? 297 ARG B C 1 ATOM 4060 O O . ARG B 1 107 ? 72.166 47.036 72.585 1.00 25.53 ? 297 ARG B O 1 ATOM 4061 C CB . ARG B 1 107 ? 68.994 47.250 72.631 1.00 21.83 ? 297 ARG B CB 1 ATOM 4062 C CG . ARG B 1 107 ? 67.765 47.345 73.523 1.00 16.44 ? 297 ARG B CG 1 ATOM 4063 C CD . ARG B 1 107 ? 66.752 46.268 73.197 1.00 18.15 ? 297 ARG B CD 1 ATOM 4064 N NE . ARG B 1 107 ? 66.304 46.323 71.809 1.00 19.25 ? 297 ARG B NE 1 ATOM 4065 C CZ . ARG B 1 107 ? 66.398 45.307 70.956 1.00 23.45 ? 297 ARG B CZ 1 ATOM 4066 N NH1 . ARG B 1 107 ? 66.929 44.152 71.347 1.00 24.70 ? 297 ARG B NH1 1 ATOM 4067 N NH2 . ARG B 1 107 ? 65.959 45.441 69.715 1.00 19.64 ? 297 ARG B NH2 1 ATOM 4068 N N . VAL B 1 108 ? 71.516 48.570 71.086 1.00 22.50 ? 298 VAL B N 1 ATOM 4069 C CA . VAL B 1 108 ? 72.664 48.328 70.213 1.00 17.84 ? 298 VAL B CA 1 ATOM 4070 C C . VAL B 1 108 ? 73.501 49.581 69.962 1.00 16.10 ? 298 VAL B C 1 ATOM 4071 O O . VAL B 1 108 ? 73.144 50.672 70.400 1.00 20.59 ? 298 VAL B O 1 ATOM 4072 C CB . VAL B 1 108 ? 72.206 47.755 68.856 1.00 17.47 ? 298 VAL B CB 1 ATOM 4073 C CG1 . VAL B 1 108 ? 71.497 46.436 69.069 1.00 14.76 ? 298 VAL B CG1 1 ATOM 4074 C CG2 . VAL B 1 108 ? 71.283 48.735 68.160 1.00 16.30 ? 298 VAL B CG2 1 ATOM 4075 N N . ILE B 1 109 ? 74.618 49.414 69.260 1.00 13.03 ? 299 ILE B N 1 ATOM 4076 C CA . ILE B 1 109 ? 75.506 50.533 68.941 1.00 15.45 ? 299 ILE B CA 1 ATOM 4077 C C . ILE B 1 109 ? 75.568 50.740 67.429 1.00 17.35 ? 299 ILE B C 1 ATOM 4078 O O . ILE B 1 109 ? 76.212 51.669 66.936 1.00 11.44 ? 299 ILE B O 1 ATOM 4079 C CB . ILE B 1 109 ? 76.936 50.278 69.447 1.00 14.02 ? 299 ILE B CB 1 ATOM 4080 C CG1 . ILE B 1 109 ? 77.476 48.990 68.825 1.00 15.71 ? 299 ILE B CG1 1 ATOM 4081 C CG2 . ILE B 1 109 ? 76.945 50.199 70.963 1.00 10.44 ? 299 ILE B CG2 1 ATOM 4082 C CD1 . ILE B 1 109 ? 78.901 48.678 69.205 1.00 20.98 ? 299 ILE B CD1 1 ATOM 4083 N N . GLY B 1 110 ? 74.895 49.853 66.704 1.00 16.49 ? 300 GLY B N 1 ATOM 4084 C CA . GLY B 1 110 ? 74.859 49.931 65.259 1.00 9.65 ? 300 GLY B CA 1 ATOM 4085 C C . GLY B 1 110 ? 73.814 48.967 64.742 1.00 11.83 ? 300 GLY B C 1 ATOM 4086 O O . GLY B 1 110 ? 73.274 48.169 65.508 1.00 12.74 ? 300 GLY B O 1 ATOM 4087 N N . LEU B 1 111 ? 73.519 49.045 63.448 1.00 9.70 ? 301 LEU B N 1 ATOM 4088 C CA . LEU B 1 111 ? 72.535 48.166 62.829 1.00 8.97 ? 301 LEU B CA 1 ATOM 4089 C C . LEU B 1 111 ? 72.622 48.301 61.311 1.00 15.41 ? 301 LEU B C 1 ATOM 4090 O O . LEU B 1 111 ? 72.942 49.375 60.789 1.00 19.19 ? 301 LEU B O 1 ATOM 4091 C CB . LEU B 1 111 ? 71.122 48.529 63.296 1.00 9.97 ? 301 LEU B CB 1 ATOM 4092 C CG . LEU B 1 111 ? 70.033 47.494 62.993 1.00 10.52 ? 301 LEU B CG 1 ATOM 4093 C CD1 . LEU B 1 111 ? 70.238 46.282 63.892 1.00 1.00 ? 301 LEU B CD1 1 ATOM 4094 C CD2 . LEU B 1 111 ? 68.653 48.094 63.226 1.00 5.28 ? 301 LEU B CD2 1 ATOM 4095 N N . ALA B 1 112 ? 72.330 47.216 60.602 1.00 10.51 ? 302 ALA B N 1 ATOM 4096 C CA . ALA B 1 112 ? 72.387 47.240 59.150 1.00 9.07 ? 302 ALA B CA 1 ATOM 4097 C C . ALA B 1 112 ? 71.764 46.003 58.526 1.00 12.13 ? 302 ALA B C 1 ATOM 4098 O O . ALA B 1 112 ? 71.741 44.932 59.131 1.00 19.15 ? 302 ALA B O 1 ATOM 4099 C CB . ALA B 1 112 ? 73.833 47.365 58.699 1.00 7.71 ? 302 ALA B CB 1 ATOM 4100 N N . TYR B 1 113 ? 71.262 46.158 57.307 1.00 13.37 ? 303 TYR B N 1 ATOM 4101 C CA . TYR B 1 113 ? 70.668 45.047 56.577 1.00 15.73 ? 303 TYR B CA 1 ATOM 4102 C C . TYR B 1 113 ? 71.774 44.040 56.265 1.00 19.42 ? 303 TYR B C 1 ATOM 4103 O O . TYR B 1 113 ? 72.949 44.405 56.198 1.00 25.04 ? 303 TYR B O 1 ATOM 4104 C CB . TYR B 1 113 ? 70.039 45.557 55.281 1.00 10.85 ? 303 TYR B CB 1 ATOM 4105 C CG . TYR B 1 113 ? 68.916 46.545 55.516 1.00 18.98 ? 303 TYR B CG 1 ATOM 4106 C CD1 . TYR B 1 113 ? 67.714 46.133 56.095 1.00 12.04 ? 303 TYR B CD1 1 ATOM 4107 C CD2 . TYR B 1 113 ? 69.067 47.900 55.199 1.00 15.41 ? 303 TYR B CD2 1 ATOM 4108 C CE1 . TYR B 1 113 ? 66.694 47.038 56.356 1.00 12.00 ? 303 TYR B CE1 1 ATOM 4109 C CE2 . TYR B 1 113 ? 68.051 48.815 55.458 1.00 15.05 ? 303 TYR B CE2 1 ATOM 4110 C CZ . TYR B 1 113 ? 66.866 48.374 56.041 1.00 16.03 ? 303 TYR B CZ 1 ATOM 4111 O OH . TYR B 1 113 ? 65.860 49.269 56.337 1.00 21.12 ? 303 TYR B OH 1 ATOM 4112 N N . VAL B 1 114 ? 71.403 42.777 56.084 1.00 17.80 ? 304 VAL B N 1 ATOM 4113 C CA . VAL B 1 114 ? 72.376 41.733 55.784 1.00 15.19 ? 304 VAL B CA 1 ATOM 4114 C C . VAL B 1 114 ? 72.384 41.372 54.297 1.00 18.09 ? 304 VAL B C 1 ATOM 4115 O O . VAL B 1 114 ? 71.334 41.302 53.660 1.00 16.03 ? 304 VAL B O 1 ATOM 4116 C CB . VAL B 1 114 ? 72.090 40.459 56.615 1.00 13.41 ? 304 VAL B CB 1 ATOM 4117 C CG1 . VAL B 1 114 ? 73.080 39.358 56.251 1.00 14.62 ? 304 VAL B CG1 1 ATOM 4118 C CG2 . VAL B 1 114 ? 72.189 40.781 58.098 1.00 7.64 ? 304 VAL B CG2 1 ATOM 4119 N N . GLY B 1 115 ? 73.577 41.139 53.752 1.00 22.68 ? 305 GLY B N 1 ATOM 4120 C CA . GLY B 1 115 ? 73.701 40.789 52.346 1.00 20.67 ? 305 GLY B CA 1 ATOM 4121 C C . GLY B 1 115 ? 72.820 41.661 51.476 1.00 21.01 ? 305 GLY B C 1 ATOM 4122 O O . GLY B 1 115 ? 71.943 41.170 50.773 1.00 19.47 ? 305 GLY B O 1 ATOM 4123 N N . SER B 1 116 ? 73.056 42.966 51.518 1.00 22.17 ? 306 SER B N 1 ATOM 4124 C CA . SER B 1 116 ? 72.251 43.895 50.745 1.00 21.09 ? 306 SER B CA 1 ATOM 4125 C C . SER B 1 116 ? 73.088 44.938 50.020 1.00 23.14 ? 306 SER B C 1 ATOM 4126 O O . SER B 1 116 ? 72.561 45.967 49.589 1.00 24.89 ? 306 SER B O 1 ATOM 4127 C CB . SER B 1 116 ? 71.264 44.595 51.671 1.00 21.48 ? 306 SER B CB 1 ATOM 4128 O OG . SER B 1 116 ? 71.958 45.269 52.705 1.00 22.92 ? 306 SER B OG 1 ATOM 4129 N N . MET B 1 117 ? 74.384 44.676 49.884 1.00 20.79 ? 307 MET B N 1 ATOM 4130 C CA . MET B 1 117 ? 75.277 45.610 49.210 1.00 19.41 ? 307 MET B CA 1 ATOM 4131 C C . MET B 1 117 ? 74.749 45.947 47.820 1.00 19.59 ? 307 MET B C 1 ATOM 4132 O O . MET B 1 117 ? 74.311 45.065 47.087 1.00 18.84 ? 307 MET B O 1 ATOM 4133 C CB . MET B 1 117 ? 76.688 45.018 49.111 1.00 18.96 ? 307 MET B CB 1 ATOM 4134 C CG . MET B 1 117 ? 77.718 45.939 48.461 1.00 17.14 ? 307 MET B CG 1 ATOM 4135 S SD . MET B 1 117 ? 77.878 47.556 49.271 1.00 22.15 ? 307 MET B SD 1 ATOM 4136 C CE . MET B 1 117 ? 78.830 47.089 50.729 1.00 12.58 ? 307 MET B CE 1 ATOM 4137 N N . CYS B 1 118 ? 74.788 47.234 47.483 1.00 20.31 ? 308 CYS B N 1 ATOM 4138 C CA . CYS B 1 118 ? 74.330 47.756 46.196 1.00 25.79 ? 308 CYS B CA 1 ATOM 4139 C C . CYS B 1 118 ? 72.831 47.984 46.113 1.00 25.65 ? 308 CYS B C 1 ATOM 4140 O O . CYS B 1 118 ? 72.351 48.612 45.175 1.00 29.50 ? 308 CYS B O 1 ATOM 4141 C CB . CYS B 1 118 ? 74.760 46.850 45.041 1.00 27.62 ? 308 CYS B CB 1 ATOM 4142 S SG . CYS B 1 118 ? 76.560 46.765 44.797 1.00 41.01 ? 308 CYS B SG 1 ATOM 4143 N N . HIS B 1 119 ? 72.085 47.476 47.083 1.00 29.59 ? 309 HIS B N 1 ATOM 4144 C CA . HIS B 1 119 ? 70.641 47.665 47.076 1.00 28.17 ? 309 HIS B CA 1 ATOM 4145 C C . HIS B 1 119 ? 70.335 49.127 47.407 1.00 28.88 ? 309 HIS B C 1 ATOM 4146 O O . HIS B 1 119 ? 70.883 49.690 48.356 1.00 23.84 ? 309 HIS B O 1 ATOM 4147 C CB . HIS B 1 119 ? 69.980 46.735 48.094 1.00 24.23 ? 309 HIS B CB 1 ATOM 4148 C CG . HIS B 1 119 ? 68.485 46.732 48.027 1.00 26.92 ? 309 HIS B CG 1 ATOM 4149 N ND1 . HIS B 1 119 ? 67.721 47.825 48.373 1.00 27.09 ? 309 HIS B ND1 1 ATOM 4150 C CD2 . HIS B 1 119 ? 67.611 45.764 47.660 1.00 29.35 ? 309 HIS B CD2 1 ATOM 4151 C CE1 . HIS B 1 119 ? 66.441 47.531 48.225 1.00 28.13 ? 309 HIS B CE1 1 ATOM 4152 N NE2 . HIS B 1 119 ? 66.348 46.286 47.793 1.00 27.20 ? 309 HIS B NE2 1 ATOM 4153 N N . PRO B 1 120 ? 69.452 49.759 46.622 1.00 29.89 ? 310 PRO B N 1 ATOM 4154 C CA . PRO B 1 120 ? 69.077 51.162 46.831 1.00 30.02 ? 310 PRO B CA 1 ATOM 4155 C C . PRO B 1 120 ? 68.673 51.521 48.258 1.00 29.46 ? 310 PRO B C 1 ATOM 4156 O O . PRO B 1 120 ? 69.165 52.499 48.820 1.00 29.18 ? 310 PRO B O 1 ATOM 4157 C CB . PRO B 1 120 ? 67.940 51.370 45.828 1.00 30.44 ? 310 PRO B CB 1 ATOM 4158 C CG . PRO B 1 120 ? 67.381 49.981 45.638 1.00 33.23 ? 310 PRO B CG 1 ATOM 4159 C CD . PRO B 1 120 ? 68.624 49.148 45.569 1.00 27.05 ? 310 PRO B CD 1 ATOM 4160 N N . LYS B 1 121 ? 67.783 50.730 48.845 1.00 28.06 ? 311 LYS B N 1 ATOM 4161 C CA . LYS B 1 121 ? 67.323 50.995 50.202 1.00 28.38 ? 311 LYS B CA 1 ATOM 4162 C C . LYS B 1 121 ? 68.123 50.271 51.280 1.00 27.60 ? 311 LYS B C 1 ATOM 4163 O O . LYS B 1 121 ? 68.374 50.825 52.350 1.00 29.67 ? 311 LYS B O 1 ATOM 4164 C CB . LYS B 1 121 ? 65.848 50.611 50.339 1.00 28.46 ? 311 LYS B CB 1 ATOM 4165 C CG . LYS B 1 121 ? 65.272 50.821 51.737 1.00 29.52 ? 311 LYS B CG 1 ATOM 4166 C CD . LYS B 1 121 ? 63.855 50.266 51.838 1.00 34.96 ? 311 LYS B CD 1 ATOM 4167 C CE . LYS B 1 121 ? 63.180 50.655 53.148 1.00 35.86 ? 311 LYS B CE 1 ATOM 4168 N NZ . LYS B 1 121 ? 63.939 50.187 54.338 1.00 38.72 ? 311 LYS B NZ 1 ATOM 4169 N N . ARG B 1 122 ? 68.532 49.038 50.994 1.00 27.59 ? 312 ARG B N 1 ATOM 4170 C CA . ARG B 1 122 ? 69.253 48.236 51.974 1.00 22.14 ? 312 ARG B CA 1 ATOM 4171 C C . ARG B 1 122 ? 70.777 48.323 52.017 1.00 22.05 ? 312 ARG B C 1 ATOM 4172 O O . ARG B 1 122 ? 71.394 47.807 52.950 1.00 15.48 ? 312 ARG B O 1 ATOM 4173 C CB . ARG B 1 122 ? 68.821 46.773 51.851 1.00 20.28 ? 312 ARG B CB 1 ATOM 4174 C CG . ARG B 1 122 ? 67.381 46.524 52.283 1.00 25.21 ? 312 ARG B CG 1 ATOM 4175 C CD . ARG B 1 122 ? 67.143 45.049 52.573 1.00 31.09 ? 312 ARG B CD 1 ATOM 4176 N NE . ARG B 1 122 ? 65.850 44.800 53.209 1.00 29.22 ? 312 ARG B NE 1 ATOM 4177 C CZ . ARG B 1 122 ? 65.548 43.685 53.871 1.00 31.10 ? 312 ARG B CZ 1 ATOM 4178 N NH1 . ARG B 1 122 ? 66.446 42.715 53.985 1.00 30.83 ? 312 ARG B NH1 1 ATOM 4179 N NH2 . ARG B 1 122 ? 64.354 43.540 54.430 1.00 25.85 ? 312 ARG B NH2 1 ATOM 4180 N N . SER B 1 123 ? 71.399 48.957 51.028 1.00 20.18 ? 313 SER B N 1 ATOM 4181 C CA . SER B 1 123 ? 72.851 49.077 51.062 1.00 17.55 ? 313 SER B CA 1 ATOM 4182 C C . SER B 1 123 ? 73.170 50.206 52.034 1.00 18.70 ? 313 SER B C 1 ATOM 4183 O O . SER B 1 123 ? 73.761 51.224 51.663 1.00 15.76 ? 313 SER B O 1 ATOM 4184 C CB . SER B 1 123 ? 73.408 49.404 49.678 1.00 15.28 ? 313 SER B CB 1 ATOM 4185 O OG . SER B 1 123 ? 74.825 49.369 49.693 1.00 23.47 ? 313 SER B OG 1 ATOM 4186 N N . THR B 1 124 ? 72.767 50.010 53.286 1.00 17.35 ? 314 THR B N 1 ATOM 4187 C CA . THR B 1 124 ? 72.967 51.006 54.331 1.00 20.60 ? 314 THR B CA 1 ATOM 4188 C C . THR B 1 124 ? 73.087 50.388 55.722 1.00 18.35 ? 314 THR B C 1 ATOM 4189 O O . THR B 1 124 ? 72.887 49.186 55.910 1.00 15.19 ? 314 THR B O 1 ATOM 4190 C CB . THR B 1 124 ? 71.789 52.004 54.367 1.00 21.54 ? 314 THR B CB 1 ATOM 4191 O OG1 . THR B 1 124 ? 70.556 51.274 54.413 1.00 22.99 ? 314 THR B OG1 1 ATOM 4192 C CG2 . THR B 1 124 ? 71.794 52.900 53.139 1.00 24.40 ? 314 THR B CG2 1 ATOM 4193 N N . GLY B 1 125 ? 73.410 51.239 56.691 1.00 14.68 ? 315 GLY B N 1 ATOM 4194 C CA . GLY B 1 125 ? 73.543 50.815 58.070 1.00 8.31 ? 315 GLY B CA 1 ATOM 4195 C C . GLY B 1 125 ? 73.732 52.045 58.939 1.00 13.80 ? 315 GLY B C 1 ATOM 4196 O O . GLY B 1 125 ? 74.088 53.113 58.436 1.00 12.80 ? 315 GLY B O 1 ATOM 4197 N N . ILE B 1 126 ? 73.486 51.921 60.238 1.00 10.29 ? 316 ILE B N 1 ATOM 4198 C CA . ILE B 1 126 ? 73.674 53.060 61.124 1.00 9.96 ? 316 ILE B CA 1 ATOM 4199 C C . ILE B 1 126 ? 74.734 52.717 62.168 1.00 11.43 ? 316 ILE B C 1 ATOM 4200 O O . ILE B 1 126 ? 74.833 51.572 62.614 1.00 12.01 ? 316 ILE B O 1 ATOM 4201 C CB . ILE B 1 126 ? 72.347 53.472 61.826 1.00 9.65 ? 316 ILE B CB 1 ATOM 4202 C CG1 . ILE B 1 126 ? 71.957 52.448 62.892 1.00 11.63 ? 316 ILE B CG1 1 ATOM 4203 C CG2 . ILE B 1 126 ? 71.235 53.570 60.802 1.00 1.00 ? 316 ILE B CG2 1 ATOM 4204 C CD1 . ILE B 1 126 ? 70.767 52.879 63.737 1.00 11.33 ? 316 ILE B CD1 1 ATOM 4205 N N . ILE B 1 127 ? 75.538 53.711 62.533 1.00 11.85 ? 317 ILE B N 1 ATOM 4206 C CA . ILE B 1 127 ? 76.596 53.536 63.519 1.00 14.87 ? 317 ILE B CA 1 ATOM 4207 C C . ILE B 1 127 ? 76.483 54.619 64.582 1.00 22.44 ? 317 ILE B C 1 ATOM 4208 O O . ILE B 1 127 ? 76.176 55.770 64.270 1.00 25.14 ? 317 ILE B O 1 ATOM 4209 C CB . ILE B 1 127 ? 78.011 53.658 62.884 1.00 16.70 ? 317 ILE B CB 1 ATOM 4210 C CG1 . ILE B 1 127 ? 78.321 52.444 62.004 1.00 18.67 ? 317 ILE B CG1 1 ATOM 4211 C CG2 . ILE B 1 127 ? 79.063 53.777 63.977 1.00 13.31 ? 317 ILE B CG2 1 ATOM 4212 C CD1 . ILE B 1 127 ? 77.572 52.419 60.700 1.00 23.07 ? 317 ILE B CD1 1 ATOM 4213 N N . GLN B 1 128 ? 76.733 54.252 65.836 1.00 23.46 ? 318 GLN B N 1 ATOM 4214 C CA . GLN B 1 128 ? 76.681 55.225 66.919 1.00 22.75 ? 318 GLN B CA 1 ATOM 4215 C C . GLN B 1 128 ? 78.096 55.652 67.269 1.00 22.17 ? 318 GLN B C 1 ATOM 4216 O O . GLN B 1 128 ? 78.980 54.807 67.412 1.00 20.35 ? 318 GLN B O 1 ATOM 4217 C CB . GLN B 1 128 ? 76.024 54.632 68.166 1.00 22.44 ? 318 GLN B CB 1 ATOM 4218 C CG . GLN B 1 128 ? 75.912 55.629 69.316 1.00 16.53 ? 318 GLN B CG 1 ATOM 4219 C CD . GLN B 1 128 ? 75.302 55.032 70.565 1.00 18.24 ? 318 GLN B CD 1 ATOM 4220 O OE1 . GLN B 1 128 ? 74.304 54.318 70.501 1.00 23.80 ? 318 GLN B OE1 1 ATOM 4221 N NE2 . GLN B 1 128 ? 75.891 55.334 71.714 1.00 8.72 ? 318 GLN B NE2 1 ATOM 4222 N N . ASP B 1 129 ? 78.306 56.963 67.392 1.00 21.75 ? 319 ASP B N 1 ATOM 4223 C CA . ASP B 1 129 ? 79.611 57.508 67.754 1.00 19.71 ? 319 ASP B CA 1 ATOM 4224 C C . ASP B 1 129 ? 79.831 57.160 69.226 1.00 18.23 ? 319 ASP B C 1 ATOM 4225 O O . ASP B 1 129 ? 79.752 58.010 70.111 1.00 16.26 ? 319 ASP B O 1 ATOM 4226 C CB . ASP B 1 129 ? 79.624 59.023 67.540 1.00 21.01 ? 319 ASP B CB 1 ATOM 4227 C CG . ASP B 1 129 ? 80.973 59.640 67.833 1.00 26.39 ? 319 ASP B CG 1 ATOM 4228 O OD1 . ASP B 1 129 ? 81.991 59.073 67.382 1.00 22.12 ? 319 ASP B OD1 1 ATOM 4229 O OD2 . ASP B 1 129 ? 81.015 60.694 68.505 1.00 28.89 ? 319 ASP B OD2 1 ATOM 4230 N N . TYR B 1 130 ? 80.110 55.881 69.448 1.00 21.91 ? 320 TYR B N 1 ATOM 4231 C CA . TYR B 1 130 ? 80.315 55.270 70.759 1.00 24.04 ? 320 TYR B CA 1 ATOM 4232 C C . TYR B 1 130 ? 81.535 55.727 71.562 1.00 24.00 ? 320 TYR B C 1 ATOM 4233 O O . TYR B 1 130 ? 81.461 55.858 72.782 1.00 23.17 ? 320 TYR B O 1 ATOM 4234 C CB . TYR B 1 130 ? 80.382 53.751 70.562 1.00 28.87 ? 320 TYR B CB 1 ATOM 4235 C CG . TYR B 1 130 ? 80.038 52.924 71.771 1.00 28.92 ? 320 TYR B CG 1 ATOM 4236 C CD1 . TYR B 1 130 ? 78.819 53.091 72.424 1.00 36.15 ? 320 TYR B CD1 1 ATOM 4237 C CD2 . TYR B 1 130 ? 80.912 51.948 72.241 1.00 26.14 ? 320 TYR B CD2 1 ATOM 4238 C CE1 . TYR B 1 130 ? 78.475 52.302 73.519 1.00 41.71 ? 320 TYR B CE1 1 ATOM 4239 C CE2 . TYR B 1 130 ? 80.580 51.153 73.334 1.00 34.44 ? 320 TYR B CE2 1 ATOM 4240 C CZ . TYR B 1 130 ? 79.359 51.334 73.968 1.00 40.56 ? 320 TYR B CZ 1 ATOM 4241 O OH . TYR B 1 130 ? 79.013 50.546 75.044 1.00 48.19 ? 320 TYR B OH 1 ATOM 4242 N N . SER B 1 131 ? 82.652 55.969 70.884 1.00 22.81 ? 321 SER B N 1 ATOM 4243 C CA . SER B 1 131 ? 83.876 56.365 71.571 1.00 22.50 ? 321 SER B CA 1 ATOM 4244 C C . SER B 1 131 ? 84.690 57.470 70.894 1.00 22.91 ? 321 SER B C 1 ATOM 4245 O O . SER B 1 131 ? 84.503 57.772 69.717 1.00 22.04 ? 321 SER B O 1 ATOM 4246 C CB . SER B 1 131 ? 84.762 55.124 71.753 1.00 22.71 ? 321 SER B CB 1 ATOM 4247 O OG . SER B 1 131 ? 86.082 55.465 72.144 1.00 20.79 ? 321 SER B OG 1 ATOM 4248 N N . GLU B 1 132 ? 85.594 58.070 71.663 1.00 23.28 ? 322 GLU B N 1 ATOM 4249 C CA . GLU B 1 132 ? 86.479 59.112 71.157 1.00 25.11 ? 322 GLU B CA 1 ATOM 4250 C C . GLU B 1 132 ? 87.546 58.446 70.299 1.00 24.03 ? 322 GLU B C 1 ATOM 4251 O O . GLU B 1 132 ? 88.125 59.068 69.409 1.00 24.00 ? 322 GLU B O 1 ATOM 4252 C CB . GLU B 1 132 ? 87.151 59.856 72.318 1.00 30.54 ? 322 GLU B CB 1 ATOM 4253 C CG . GLU B 1 132 ? 86.470 61.159 72.695 1.00 40.79 ? 322 GLU B CG 1 ATOM 4254 C CD . GLU B 1 132 ? 86.543 62.198 71.584 1.00 45.67 ? 322 GLU B CD 1 ATOM 4255 O OE1 . GLU B 1 132 ? 85.885 63.255 71.711 1.00 50.04 ? 322 GLU B OE1 1 ATOM 4256 O OE2 . GLU B 1 132 ? 87.263 61.961 70.586 1.00 48.19 ? 322 GLU B OE2 1 ATOM 4257 N N . ILE B 1 133 ? 87.792 57.170 70.586 1.00 22.69 ? 323 ILE B N 1 ATOM 4258 C CA . ILE B 1 133 ? 88.780 56.369 69.872 1.00 19.83 ? 323 ILE B CA 1 ATOM 4259 C C . ILE B 1 133 ? 88.297 56.060 68.459 1.00 20.26 ? 323 ILE B C 1 ATOM 4260 O O . ILE B 1 133 ? 87.299 55.361 68.275 1.00 24.70 ? 323 ILE B O 1 ATOM 4261 C CB . ILE B 1 133 ? 89.028 55.041 70.604 1.00 20.27 ? 323 ILE B CB 1 ATOM 4262 C CG1 . ILE B 1 133 ? 89.311 55.311 72.080 1.00 11.91 ? 323 ILE B CG1 1 ATOM 4263 C CG2 . ILE B 1 133 ? 90.187 54.302 69.959 1.00 16.02 ? 323 ILE B CG2 1 ATOM 4264 C CD1 . ILE B 1 133 ? 89.508 54.060 72.898 1.00 13.35 ? 323 ILE B CD1 1 ATOM 4265 N N . ASN B 1 134 ? 89.017 56.568 67.465 1.00 17.97 ? 324 ASN B N 1 ATOM 4266 C CA . ASN B 1 134 ? 88.644 56.364 66.072 1.00 14.89 ? 324 ASN B CA 1 ATOM 4267 C C . ASN B 1 134 ? 88.562 54.909 65.642 1.00 13.91 ? 324 ASN B C 1 ATOM 4268 O O . ASN B 1 134 ? 87.659 54.531 64.898 1.00 17.69 ? 324 ASN B O 1 ATOM 4269 C CB . ASN B 1 134 ? 89.596 57.146 65.168 1.00 7.80 ? 324 ASN B CB 1 ATOM 4270 C CG . ASN B 1 134 ? 89.438 58.643 65.341 1.00 15.90 ? 324 ASN B CG 1 ATOM 4271 O OD1 . ASN B 1 134 ? 90.149 59.440 64.730 1.00 18.21 ? 324 ASN B OD1 1 ATOM 4272 N ND2 . ASN B 1 134 ? 88.492 59.034 66.187 1.00 19.38 ? 324 ASN B ND2 1 ATOM 4273 N N . LEU B 1 135 ? 89.493 54.086 66.108 1.00 15.53 ? 325 LEU B N 1 ATOM 4274 C CA . LEU B 1 135 ? 89.480 52.670 65.752 1.00 15.04 ? 325 LEU B CA 1 ATOM 4275 C C . LEU B 1 135 ? 88.179 51.998 66.207 1.00 15.75 ? 325 LEU B C 1 ATOM 4276 O O . LEU B 1 135 ? 87.613 51.171 65.488 1.00 16.78 ? 325 LEU B O 1 ATOM 4277 C CB . LEU B 1 135 ? 90.682 51.960 66.379 1.00 8.41 ? 325 LEU B CB 1 ATOM 4278 C CG . LEU B 1 135 ? 90.726 50.438 66.253 1.00 6.10 ? 325 LEU B CG 1 ATOM 4279 C CD1 . LEU B 1 135 ? 90.733 50.032 64.786 1.00 8.28 ? 325 LEU B CD1 1 ATOM 4280 C CD2 . LEU B 1 135 ? 91.961 49.910 66.967 1.00 4.49 ? 325 LEU B CD2 1 ATOM 4281 N N . VAL B 1 136 ? 87.704 52.360 67.397 1.00 14.28 ? 326 VAL B N 1 ATOM 4282 C CA . VAL B 1 136 ? 86.471 51.786 67.924 1.00 14.37 ? 326 VAL B CA 1 ATOM 4283 C C . VAL B 1 136 ? 85.311 52.049 66.970 1.00 15.06 ? 326 VAL B C 1 ATOM 4284 O O . VAL B 1 136 ? 84.557 51.134 66.633 1.00 22.36 ? 326 VAL B O 1 ATOM 4285 C CB . VAL B 1 136 ? 86.124 52.366 69.326 1.00 17.28 ? 326 VAL B CB 1 ATOM 4286 C CG1 . VAL B 1 136 ? 84.741 51.908 69.765 1.00 1.00 ? 326 VAL B CG1 1 ATOM 4287 C CG2 . VAL B 1 136 ? 87.157 51.912 70.343 1.00 12.06 ? 326 VAL B CG2 1 ATOM 4288 N N . VAL B 1 137 ? 85.170 53.297 66.535 1.00 10.93 ? 327 VAL B N 1 ATOM 4289 C CA . VAL B 1 137 ? 84.095 53.661 65.614 1.00 11.32 ? 327 VAL B CA 1 ATOM 4290 C C . VAL B 1 137 ? 84.329 53.058 64.223 1.00 11.94 ? 327 VAL B C 1 ATOM 4291 O O . VAL B 1 137 ? 83.376 52.746 63.507 1.00 11.63 ? 327 VAL B O 1 ATOM 4292 C CB . VAL B 1 137 ? 83.953 55.204 65.501 1.00 9.15 ? 327 VAL B CB 1 ATOM 4293 C CG1 . VAL B 1 137 ? 82.946 55.567 64.433 1.00 6.20 ? 327 VAL B CG1 1 ATOM 4294 C CG2 . VAL B 1 137 ? 83.502 55.777 66.832 1.00 3.92 ? 327 VAL B CG2 1 ATOM 4295 N N . ALA B 1 138 ? 85.593 52.888 63.848 1.00 5.51 ? 328 ALA B N 1 ATOM 4296 C CA . ALA B 1 138 ? 85.928 52.313 62.551 1.00 11.95 ? 328 ALA B CA 1 ATOM 4297 C C . ALA B 1 138 ? 85.497 50.849 62.495 1.00 17.31 ? 328 ALA B C 1 ATOM 4298 O O . ALA B 1 138 ? 84.929 50.396 61.496 1.00 16.43 ? 328 ALA B O 1 ATOM 4299 C CB . ALA B 1 138 ? 87.425 52.427 62.295 1.00 15.63 ? 328 ALA B CB 1 ATOM 4300 N N . VAL B 1 139 ? 85.768 50.112 63.569 1.00 15.89 ? 329 VAL B N 1 ATOM 4301 C CA . VAL B 1 139 ? 85.399 48.704 63.626 1.00 14.60 ? 329 VAL B CA 1 ATOM 4302 C C . VAL B 1 139 ? 83.884 48.540 63.518 1.00 12.40 ? 329 VAL B C 1 ATOM 4303 O O . VAL B 1 139 ? 83.406 47.628 62.839 1.00 14.53 ? 329 VAL B O 1 ATOM 4304 C CB . VAL B 1 139 ? 85.909 48.032 64.936 1.00 20.29 ? 329 VAL B CB 1 ATOM 4305 C CG1 . VAL B 1 139 ? 85.466 46.576 64.991 1.00 17.78 ? 329 VAL B CG1 1 ATOM 4306 C CG2 . VAL B 1 139 ? 87.428 48.095 64.997 1.00 15.48 ? 329 VAL B CG2 1 ATOM 4307 N N . ILE B 1 140 ? 83.130 49.418 64.177 1.00 11.02 ? 330 ILE B N 1 ATOM 4308 C CA . ILE B 1 140 ? 81.664 49.349 64.123 1.00 11.13 ? 330 ILE B CA 1 ATOM 4309 C C . ILE B 1 140 ? 81.196 49.546 62.681 1.00 8.39 ? 330 ILE B C 1 ATOM 4310 O O . ILE B 1 140 ? 80.368 48.788 62.169 1.00 2.97 ? 330 ILE B O 1 ATOM 4311 C CB . ILE B 1 140 ? 80.984 50.451 64.987 1.00 12.05 ? 330 ILE B CB 1 ATOM 4312 C CG1 . ILE B 1 140 ? 81.474 50.387 66.433 1.00 11.83 ? 330 ILE B CG1 1 ATOM 4313 C CG2 . ILE B 1 140 ? 79.477 50.268 64.957 1.00 5.04 ? 330 ILE B CG2 1 ATOM 4314 C CD1 . ILE B 1 140 ? 80.789 51.383 67.347 1.00 3.72 ? 330 ILE B CD1 1 ATOM 4315 N N . MET B 1 141 ? 81.734 50.578 62.039 1.00 10.42 ? 331 MET B N 1 ATOM 4316 C CA . MET B 1 141 ? 81.391 50.896 60.661 1.00 14.97 ? 331 MET B CA 1 ATOM 4317 C C . MET B 1 141 ? 81.708 49.690 59.774 1.00 15.57 ? 331 MET B C 1 ATOM 4318 O O . MET B 1 141 ? 80.863 49.232 59.002 1.00 18.16 ? 331 MET B O 1 ATOM 4319 C CB . MET B 1 141 ? 82.186 52.123 60.205 1.00 19.26 ? 331 MET B CB 1 ATOM 4320 C CG . MET B 1 141 ? 81.629 52.820 58.969 1.00 29.77 ? 331 MET B CG 1 ATOM 4321 S SD . MET B 1 141 ? 82.541 54.331 58.545 1.00 33.46 ? 331 MET B SD 1 ATOM 4322 C CE . MET B 1 141 ? 82.110 55.378 59.950 1.00 16.02 ? 331 MET B CE 1 ATOM 4323 N N . ALA B 1 142 ? 82.927 49.173 59.893 1.00 15.72 ? 332 ALA B N 1 ATOM 4324 C CA . ALA B 1 142 ? 83.334 48.014 59.107 1.00 15.76 ? 332 ALA B CA 1 ATOM 4325 C C . ALA B 1 142 ? 82.388 46.864 59.427 1.00 18.58 ? 332 ALA B C 1 ATOM 4326 O O . ALA B 1 142 ? 81.976 46.111 58.537 1.00 15.83 ? 332 ALA B O 1 ATOM 4327 C CB . ALA B 1 142 ? 84.763 47.625 59.445 1.00 16.19 ? 332 ALA B CB 1 ATOM 4328 N N . HIS B 1 143 ? 82.048 46.740 60.707 1.00 17.45 ? 333 HIS B N 1 ATOM 4329 C CA . HIS B 1 143 ? 81.146 45.693 61.163 1.00 14.32 ? 333 HIS B CA 1 ATOM 4330 C C . HIS B 1 143 ? 79.828 45.794 60.406 1.00 14.16 ? 333 HIS B C 1 ATOM 4331 O O . HIS B 1 143 ? 79.377 44.824 59.796 1.00 12.66 ? 333 HIS B O 1 ATOM 4332 C CB . HIS B 1 143 ? 80.878 45.835 62.662 1.00 17.47 ? 333 HIS B CB 1 ATOM 4333 C CG . HIS B 1 143 ? 80.000 44.759 63.224 1.00 18.30 ? 333 HIS B CG 1 ATOM 4334 N ND1 . HIS B 1 143 ? 80.503 43.603 63.785 1.00 9.36 ? 333 HIS B ND1 1 ATOM 4335 C CD2 . HIS B 1 143 ? 78.651 44.649 63.279 1.00 10.71 ? 333 HIS B CD2 1 ATOM 4336 C CE1 . HIS B 1 143 ? 79.500 42.829 64.161 1.00 13.84 ? 333 HIS B CE1 1 ATOM 4337 N NE2 . HIS B 1 143 ? 78.367 43.440 63.864 1.00 13.08 ? 333 HIS B NE2 1 ATOM 4338 N N . GLU B 1 144 ? 79.216 46.977 60.447 1.00 15.44 ? 334 GLU B N 1 ATOM 4339 C CA . GLU B 1 144 ? 77.945 47.197 59.771 1.00 16.23 ? 334 GLU B CA 1 ATOM 4340 C C . GLU B 1 144 ? 78.030 46.930 58.271 1.00 17.32 ? 334 GLU B C 1 ATOM 4341 O O . GLU B 1 144 ? 77.134 46.302 57.699 1.00 14.17 ? 334 GLU B O 1 ATOM 4342 C CB . GLU B 1 144 ? 77.438 48.620 60.025 1.00 15.33 ? 334 GLU B CB 1 ATOM 4343 C CG . GLU B 1 144 ? 77.012 48.884 61.467 1.00 17.32 ? 334 GLU B CG 1 ATOM 4344 C CD . GLU B 1 144 ? 76.186 47.750 62.059 1.00 18.45 ? 334 GLU B CD 1 ATOM 4345 O OE1 . GLU B 1 144 ? 75.449 47.083 61.302 1.00 20.25 ? 334 GLU B OE1 1 ATOM 4346 O OE2 . GLU B 1 144 ? 76.265 47.531 63.286 1.00 15.65 ? 334 GLU B OE2 1 ATOM 4347 N N . MET B 1 145 ? 79.094 47.406 57.630 1.00 16.35 ? 335 MET B N 1 ATOM 4348 C CA . MET B 1 145 ? 79.256 47.163 56.203 1.00 18.57 ? 335 MET B CA 1 ATOM 4349 C C . MET B 1 145 ? 79.409 45.662 55.991 1.00 19.78 ? 335 MET B C 1 ATOM 4350 O O . MET B 1 145 ? 78.998 45.123 54.964 1.00 19.27 ? 335 MET B O 1 ATOM 4351 C CB . MET B 1 145 ? 80.477 47.903 55.658 1.00 22.93 ? 335 MET B CB 1 ATOM 4352 C CG . MET B 1 145 ? 80.159 49.285 55.111 1.00 32.40 ? 335 MET B CG 1 ATOM 4353 S SD . MET B 1 145 ? 81.578 50.073 54.329 1.00 38.70 ? 335 MET B SD 1 ATOM 4354 C CE . MET B 1 145 ? 81.913 48.899 52.990 1.00 26.75 ? 335 MET B CE 1 ATOM 4355 N N . GLY B 1 146 ? 80.001 44.991 56.975 1.00 18.54 ? 336 GLY B N 1 ATOM 4356 C CA . GLY B 1 146 ? 80.169 43.554 56.886 1.00 19.35 ? 336 GLY B CA 1 ATOM 4357 C C . GLY B 1 146 ? 78.808 42.901 56.722 1.00 22.59 ? 336 GLY B C 1 ATOM 4358 O O . GLY B 1 146 ? 78.616 42.029 55.871 1.00 27.16 ? 336 GLY B O 1 ATOM 4359 N N . HIS B 1 147 ? 77.852 43.324 57.541 1.00 17.79 ? 337 HIS B N 1 ATOM 4360 C CA . HIS B 1 147 ? 76.509 42.781 57.452 1.00 15.91 ? 337 HIS B CA 1 ATOM 4361 C C . HIS B 1 147 ? 75.972 43.036 56.048 1.00 20.76 ? 337 HIS B C 1 ATOM 4362 O O . HIS B 1 147 ? 75.254 42.207 55.493 1.00 26.33 ? 337 HIS B O 1 ATOM 4363 C CB . HIS B 1 147 ? 75.594 43.437 58.487 1.00 15.71 ? 337 HIS B CB 1 ATOM 4364 C CG . HIS B 1 147 ? 75.763 42.900 59.875 1.00 20.39 ? 337 HIS B CG 1 ATOM 4365 N ND1 . HIS B 1 147 ? 75.577 41.571 60.185 1.00 23.96 ? 337 HIS B ND1 1 ATOM 4366 C CD2 . HIS B 1 147 ? 76.075 43.517 61.040 1.00 20.65 ? 337 HIS B CD2 1 ATOM 4367 C CE1 . HIS B 1 147 ? 75.766 41.392 61.480 1.00 18.66 ? 337 HIS B CE1 1 ATOM 4368 N NE2 . HIS B 1 147 ? 76.069 42.557 62.022 1.00 8.14 ? 337 HIS B NE2 1 ATOM 4369 N N . ASN B 1 148 ? 76.326 44.184 55.476 1.00 19.36 ? 338 ASN B N 1 ATOM 4370 C CA . ASN B 1 148 ? 75.877 44.538 54.132 1.00 20.51 ? 338 ASN B CA 1 ATOM 4371 C C . ASN B 1 148 ? 76.453 43.587 53.087 1.00 21.64 ? 338 ASN B C 1 ATOM 4372 O O . ASN B 1 148 ? 75.829 43.326 52.059 1.00 20.57 ? 338 ASN B O 1 ATOM 4373 C CB . ASN B 1 148 ? 76.291 45.975 53.787 1.00 18.91 ? 338 ASN B CB 1 ATOM 4374 C CG . ASN B 1 148 ? 75.384 47.014 54.413 1.00 21.62 ? 338 ASN B CG 1 ATOM 4375 O OD1 . ASN B 1 148 ? 75.641 48.215 54.313 1.00 20.31 ? 338 ASN B OD1 1 ATOM 4376 N ND2 . ASN B 1 148 ? 74.311 46.560 55.056 1.00 21.67 ? 338 ASN B ND2 1 ATOM 4377 N N . LEU B 1 149 ? 77.649 43.075 53.357 1.00 22.71 ? 339 LEU B N 1 ATOM 4378 C CA . LEU B 1 149 ? 78.316 42.161 52.441 1.00 24.23 ? 339 LEU B CA 1 ATOM 4379 C C . LEU B 1 149 ? 77.980 40.693 52.716 1.00 24.22 ? 339 LEU B C 1 ATOM 4380 O O . LEU B 1 149 ? 78.767 39.795 52.401 1.00 24.98 ? 339 LEU B O 1 ATOM 4381 C CB . LEU B 1 149 ? 79.830 42.377 52.515 1.00 23.89 ? 339 LEU B CB 1 ATOM 4382 C CG . LEU B 1 149 ? 80.326 43.719 51.978 1.00 24.98 ? 339 LEU B CG 1 ATOM 4383 C CD1 . LEU B 1 149 ? 81.809 43.882 52.262 1.00 23.90 ? 339 LEU B CD1 1 ATOM 4384 C CD2 . LEU B 1 149 ? 80.057 43.790 50.484 1.00 29.05 ? 339 LEU B CD2 1 ATOM 4385 N N . GLY B 1 150 ? 76.809 40.457 53.301 1.00 19.34 ? 340 GLY B N 1 ATOM 4386 C CA . GLY B 1 150 ? 76.382 39.102 53.598 1.00 19.68 ? 340 GLY B CA 1 ATOM 4387 C C . GLY B 1 150 ? 77.149 38.390 54.702 1.00 21.57 ? 340 GLY B C 1 ATOM 4388 O O . GLY B 1 150 ? 77.005 37.178 54.874 1.00 20.96 ? 340 GLY B O 1 ATOM 4389 N N . ILE B 1 151 ? 77.960 39.128 55.455 1.00 18.45 ? 341 ILE B N 1 ATOM 4390 C CA . ILE B 1 151 ? 78.738 38.535 56.537 1.00 18.06 ? 341 ILE B CA 1 ATOM 4391 C C . ILE B 1 151 ? 77.936 38.534 57.834 1.00 18.22 ? 341 ILE B C 1 ATOM 4392 O O . ILE B 1 151 ? 77.171 39.460 58.101 1.00 17.04 ? 341 ILE B O 1 ATOM 4393 C CB . ILE B 1 151 ? 80.055 39.308 56.781 1.00 16.07 ? 341 ILE B CB 1 ATOM 4394 C CG1 . ILE B 1 151 ? 80.826 39.455 55.467 1.00 15.72 ? 341 ILE B CG1 1 ATOM 4395 C CG2 . ILE B 1 151 ? 80.904 38.573 57.814 1.00 12.48 ? 341 ILE B CG2 1 ATOM 4396 C CD1 . ILE B 1 151 ? 82.093 40.281 55.579 1.00 1.00 ? 341 ILE B CD1 1 ATOM 4397 N N . ASN B 1 152 ? 78.121 37.491 58.637 1.00 17.79 ? 342 ASN B N 1 ATOM 4398 C CA . ASN B 1 152 ? 77.416 37.372 59.906 1.00 18.72 ? 342 ASN B CA 1 ATOM 4399 C C . ASN B 1 152 ? 78.387 37.416 61.078 1.00 21.10 ? 342 ASN B C 1 ATOM 4400 O O . ASN B 1 152 ? 79.583 37.645 60.892 1.00 22.99 ? 342 ASN B O 1 ATOM 4401 C CB . ASN B 1 152 ? 76.601 36.079 59.930 1.00 24.56 ? 342 ASN B CB 1 ATOM 4402 C CG . ASN B 1 152 ? 75.419 36.118 58.968 1.00 35.62 ? 342 ASN B CG 1 ATOM 4403 O OD1 . ASN B 1 152 ? 74.461 36.868 59.171 1.00 33.95 ? 342 ASN B OD1 1 ATOM 4404 N ND2 . ASN B 1 152 ? 75.488 35.313 57.911 1.00 38.91 ? 342 ASN B ND2 1 ATOM 4405 N N . HIS B 1 153 ? 77.873 37.200 62.284 1.00 20.96 ? 343 HIS B N 1 ATOM 4406 C CA . HIS B 1 153 ? 78.704 37.238 63.481 1.00 20.39 ? 343 HIS B CA 1 ATOM 4407 C C . HIS B 1 153 ? 79.550 35.996 63.670 1.00 21.54 ? 343 HIS B C 1 ATOM 4408 O O . HIS B 1 153 ? 79.190 34.910 63.224 1.00 22.90 ? 343 HIS B O 1 ATOM 4409 C CB . HIS B 1 153 ? 77.833 37.459 64.717 1.00 18.74 ? 343 HIS B CB 1 ATOM 4410 C CG . HIS B 1 153 ? 77.211 38.819 64.774 1.00 20.60 ? 343 HIS B CG 1 ATOM 4411 N ND1 . HIS B 1 153 ? 76.261 39.165 65.708 1.00 18.23 ? 343 HIS B ND1 1 ATOM 4412 C CD2 . HIS B 1 153 ? 77.410 39.921 64.013 1.00 20.48 ? 343 HIS B CD2 1 ATOM 4413 C CE1 . HIS B 1 153 ? 75.900 40.422 65.520 1.00 24.66 ? 343 HIS B CE1 1 ATOM 4414 N NE2 . HIS B 1 153 ? 76.583 40.903 64.498 1.00 23.75 ? 343 HIS B NE2 1 ATOM 4415 N N . ASP B 1 154 ? 80.689 36.168 64.331 1.00 23.60 ? 344 ASP B N 1 ATOM 4416 C CA . ASP B 1 154 ? 81.586 35.053 64.583 1.00 26.28 ? 344 ASP B CA 1 ATOM 4417 C C . ASP B 1 154 ? 81.040 34.175 65.700 1.00 28.80 ? 344 ASP B C 1 ATOM 4418 O O . ASP B 1 154 ? 80.477 34.664 66.682 1.00 31.29 ? 344 ASP B O 1 ATOM 4419 C CB . ASP B 1 154 ? 82.984 35.559 64.957 1.00 26.89 ? 344 ASP B CB 1 ATOM 4420 C CG . ASP B 1 154 ? 83.673 36.273 63.808 1.00 26.42 ? 344 ASP B CG 1 ATOM 4421 O OD1 . ASP B 1 154 ? 83.615 35.760 62.672 1.00 21.66 ? 344 ASP B OD1 1 ATOM 4422 O OD2 . ASP B 1 154 ? 84.281 37.339 64.039 1.00 30.50 ? 344 ASP B OD2 1 ATOM 4423 N N . SER B 1 155 ? 81.204 32.870 65.537 1.00 30.64 ? 345 SER B N 1 ATOM 4424 C CA . SER B 1 155 ? 80.740 31.914 66.528 1.00 30.49 ? 345 SER B CA 1 ATOM 4425 C C . SER B 1 155 ? 81.706 30.750 66.544 1.00 32.02 ? 345 SER B C 1 ATOM 4426 O O . SER B 1 155 ? 82.500 30.580 65.617 1.00 34.73 ? 345 SER B O 1 ATOM 4427 C CB . SER B 1 155 ? 79.351 31.404 66.164 1.00 31.62 ? 345 SER B CB 1 ATOM 4428 O OG . SER B 1 155 ? 79.386 30.728 64.920 1.00 42.26 ? 345 SER B OG 1 ATOM 4429 N N . GLY B 1 156 ? 81.638 29.949 67.598 1.00 29.04 ? 346 GLY B N 1 ATOM 4430 C CA . GLY B 1 156 ? 82.518 28.804 67.692 1.00 30.75 ? 346 GLY B CA 1 ATOM 4431 C C . GLY B 1 156 ? 83.982 29.143 67.494 1.00 30.77 ? 346 GLY B C 1 ATOM 4432 O O . GLY B 1 156 ? 84.476 30.150 68.002 1.00 31.00 ? 346 GLY B O 1 ATOM 4433 N N . TYR B 1 157 ? 84.673 28.310 66.726 1.00 27.48 ? 347 TYR B N 1 ATOM 4434 C CA . TYR B 1 157 ? 86.092 28.501 66.498 1.00 23.67 ? 347 TYR B CA 1 ATOM 4435 C C . TYR B 1 157 ? 86.508 29.448 65.384 1.00 23.73 ? 347 TYR B C 1 ATOM 4436 O O . TYR B 1 157 ? 87.579 29.282 64.803 1.00 24.02 ? 347 TYR B O 1 ATOM 4437 C CB . TYR B 1 157 ? 86.764 27.139 66.304 1.00 25.41 ? 347 TYR B CB 1 ATOM 4438 C CG . TYR B 1 157 ? 86.776 26.313 67.569 1.00 22.91 ? 347 TYR B CG 1 ATOM 4439 C CD1 . TYR B 1 157 ? 85.608 25.730 68.057 1.00 22.17 ? 347 TYR B CD1 1 ATOM 4440 C CD2 . TYR B 1 157 ? 87.943 26.175 68.318 1.00 21.44 ? 347 TYR B CD2 1 ATOM 4441 C CE1 . TYR B 1 157 ? 85.603 25.035 69.264 1.00 19.65 ? 347 TYR B CE1 1 ATOM 4442 C CE2 . TYR B 1 157 ? 87.947 25.484 69.522 1.00 18.14 ? 347 TYR B CE2 1 ATOM 4443 C CZ . TYR B 1 157 ? 86.776 24.919 69.991 1.00 16.90 ? 347 TYR B CZ 1 ATOM 4444 O OH . TYR B 1 157 ? 86.780 24.257 71.195 1.00 19.40 ? 347 TYR B OH 1 ATOM 4445 N N . CYS B 1 158 ? 85.678 30.440 65.078 1.00 26.65 ? 348 CYS B N 1 ATOM 4446 C CA . CYS B 1 158 ? 86.053 31.408 64.053 1.00 25.55 ? 348 CYS B CA 1 ATOM 4447 C C . CYS B 1 158 ? 87.245 32.145 64.646 1.00 25.97 ? 348 CYS B C 1 ATOM 4448 O O . CYS B 1 158 ? 87.222 32.531 65.815 1.00 25.72 ? 348 CYS B O 1 ATOM 4449 C CB . CYS B 1 158 ? 84.906 32.378 63.759 1.00 25.67 ? 348 CYS B CB 1 ATOM 4450 S SG . CYS B 1 158 ? 83.528 31.623 62.831 1.00 32.80 ? 348 CYS B SG 1 ATOM 4451 N N . SER B 1 159 ? 88.292 32.332 63.852 1.00 26.88 ? 349 SER B N 1 ATOM 4452 C CA . SER B 1 159 ? 89.495 32.977 64.356 1.00 26.05 ? 349 SER B CA 1 ATOM 4453 C C . SER B 1 159 ? 90.103 33.999 63.406 1.00 26.73 ? 349 SER B C 1 ATOM 4454 O O . SER B 1 159 ? 89.875 33.969 62.195 1.00 24.37 ? 349 SER B O 1 ATOM 4455 C CB . SER B 1 159 ? 90.536 31.898 64.694 1.00 26.57 ? 349 SER B CB 1 ATOM 4456 O OG . SER B 1 159 ? 91.682 32.437 65.330 1.00 29.85 ? 349 SER B OG 1 ATOM 4457 N N . CYS B 1 160 ? 90.877 34.910 63.985 1.00 23.10 ? 350 CYS B N 1 ATOM 4458 C CA . CYS B 1 160 ? 91.570 35.957 63.250 1.00 24.30 ? 350 CYS B CA 1 ATOM 4459 C C . CYS B 1 160 ? 92.818 36.206 64.090 1.00 26.84 ? 350 CYS B C 1 ATOM 4460 O O . CYS B 1 160 ? 93.334 37.322 64.161 1.00 29.12 ? 350 CYS B O 1 ATOM 4461 C CB . CYS B 1 160 ? 90.709 37.228 63.178 1.00 24.10 ? 350 CYS B CB 1 ATOM 4462 S SG . CYS B 1 160 ? 90.439 38.031 64.794 1.00 33.89 ? 350 CYS B SG 1 ATOM 4463 N N . GLY B 1 161 ? 93.294 35.137 64.724 1.00 26.60 ? 351 GLY B N 1 ATOM 4464 C CA . GLY B 1 161 ? 94.452 35.228 65.592 1.00 27.22 ? 351 GLY B CA 1 ATOM 4465 C C . GLY B 1 161 ? 93.913 35.444 66.992 1.00 34.47 ? 351 GLY B C 1 ATOM 4466 O O . GLY B 1 161 ? 92.702 35.344 67.204 1.00 36.95 ? 351 GLY B O 1 ATOM 4467 N N . ASP B 1 162 ? 94.781 35.741 67.951 1.00 38.52 ? 352 ASP B N 1 ATOM 4468 C CA . ASP B 1 162 ? 94.317 35.969 69.317 1.00 48.03 ? 352 ASP B CA 1 ATOM 4469 C C . ASP B 1 162 ? 93.835 37.411 69.492 1.00 48.44 ? 352 ASP B C 1 ATOM 4470 O O . ASP B 1 162 ? 94.151 38.066 70.488 1.00 51.12 ? 352 ASP B O 1 ATOM 4471 C CB . ASP B 1 162 ? 95.439 35.670 70.319 1.00 54.93 ? 352 ASP B CB 1 ATOM 4472 C CG . ASP B 1 162 ? 96.604 36.641 70.206 1.00 60.10 ? 352 ASP B CG 1 ATOM 4473 O OD1 . ASP B 1 162 ? 97.581 36.482 70.970 1.00 60.27 ? 352 ASP B OD1 1 ATOM 4474 O OD2 . ASP B 1 162 ? 96.543 37.561 69.359 1.00 61.36 ? 352 ASP B OD2 1 ATOM 4475 N N . TYR B 1 163 ? 93.066 37.899 68.523 1.00 44.30 ? 353 TYR B N 1 ATOM 4476 C CA . TYR B 1 163 ? 92.553 39.266 68.565 1.00 40.06 ? 353 TYR B CA 1 ATOM 4477 C C . TYR B 1 163 ? 91.030 39.301 68.507 1.00 34.25 ? 353 TYR B C 1 ATOM 4478 O O . TYR B 1 163 ? 90.400 38.395 67.965 1.00 34.41 ? 353 TYR B O 1 ATOM 4479 C CB . TYR B 1 163 ? 93.085 40.064 67.376 1.00 42.52 ? 353 TYR B CB 1 ATOM 4480 C CG . TYR B 1 163 ? 94.585 40.066 67.217 1.00 43.26 ? 353 TYR B CG 1 ATOM 4481 C CD1 . TYR B 1 163 ? 95.397 40.847 68.038 1.00 44.20 ? 353 TYR B CD1 1 ATOM 4482 C CD2 . TYR B 1 163 ? 95.193 39.311 66.215 1.00 45.56 ? 353 TYR B CD2 1 ATOM 4483 C CE1 . TYR B 1 163 ? 96.779 40.882 67.859 1.00 45.91 ? 353 TYR B CE1 1 ATOM 4484 C CE2 . TYR B 1 163 ? 96.571 39.336 66.027 1.00 44.39 ? 353 TYR B CE2 1 ATOM 4485 C CZ . TYR B 1 163 ? 97.357 40.124 66.850 1.00 45.88 ? 353 TYR B CZ 1 ATOM 4486 O OH . TYR B 1 163 ? 98.716 40.165 66.647 1.00 45.93 ? 353 TYR B OH 1 ATOM 4487 N N . ALA B 1 164 ? 90.442 40.355 69.061 1.00 30.33 ? 354 ALA B N 1 ATOM 4488 C CA . ALA B 1 164 ? 88.994 40.511 69.025 1.00 25.69 ? 354 ALA B CA 1 ATOM 4489 C C . ALA B 1 164 ? 88.663 40.822 67.568 1.00 24.57 ? 354 ALA B C 1 ATOM 4490 O O . ALA B 1 164 ? 88.948 41.916 67.080 1.00 18.77 ? 354 ALA B O 1 ATOM 4491 C CB . ALA B 1 164 ? 88.569 41.657 69.922 1.00 17.79 ? 354 ALA B CB 1 ATOM 4492 N N . CYS B 1 165 ? 88.068 39.855 66.877 1.00 24.13 ? 355 CYS B N 1 ATOM 4493 C CA . CYS B 1 165 ? 87.745 40.020 65.467 1.00 26.79 ? 355 CYS B CA 1 ATOM 4494 C C . CYS B 1 165 ? 86.596 40.985 65.207 1.00 27.61 ? 355 CYS B C 1 ATOM 4495 O O . CYS B 1 165 ? 85.735 41.198 66.060 1.00 29.27 ? 355 CYS B O 1 ATOM 4496 C CB . CYS B 1 165 ? 87.453 38.651 64.843 1.00 28.60 ? 355 CYS B CB 1 ATOM 4497 S SG . CYS B 1 165 ? 88.618 37.367 65.407 1.00 37.00 ? 355 CYS B SG 1 ATOM 4498 N N . ILE B 1 166 ? 86.599 41.563 64.011 1.00 24.70 ? 356 ILE B N 1 ATOM 4499 C CA . ILE B 1 166 ? 85.592 42.531 63.601 1.00 23.55 ? 356 ILE B CA 1 ATOM 4500 C C . ILE B 1 166 ? 84.147 42.063 63.768 1.00 26.06 ? 356 ILE B C 1 ATOM 4501 O O . ILE B 1 166 ? 83.339 42.756 64.387 1.00 29.79 ? 356 ILE B O 1 ATOM 4502 C CB . ILE B 1 166 ? 85.788 42.947 62.121 1.00 19.12 ? 356 ILE B CB 1 ATOM 4503 C CG1 . ILE B 1 166 ? 87.218 43.443 61.894 1.00 17.53 ? 356 ILE B CG1 1 ATOM 4504 C CG2 . ILE B 1 166 ? 84.795 44.040 61.752 1.00 18.14 ? 356 ILE B CG2 1 ATOM 4505 C CD1 . ILE B 1 166 ? 87.568 44.719 62.628 1.00 14.04 ? 356 ILE B CD1 1 ATOM 4506 N N . MET B 1 167 ? 83.818 40.894 63.224 1.00 22.26 ? 357 MET B N 1 ATOM 4507 C CA . MET B 1 167 ? 82.448 40.407 63.306 1.00 21.06 ? 357 MET B CA 1 ATOM 4508 C C . MET B 1 167 ? 82.007 39.696 64.586 1.00 20.82 ? 357 MET B C 1 ATOM 4509 O O . MET B 1 167 ? 81.083 38.884 64.555 1.00 20.09 ? 357 MET B O 1 ATOM 4510 C CB . MET B 1 167 ? 82.124 39.530 62.093 1.00 18.71 ? 357 MET B CB 1 ATOM 4511 C CG . MET B 1 167 ? 82.129 40.289 60.773 1.00 21.98 ? 357 MET B CG 1 ATOM 4512 S SD . MET B 1 167 ? 81.326 41.923 60.854 1.00 20.14 ? 357 MET B SD 1 ATOM 4513 C CE . MET B 1 167 ? 79.581 41.468 60.849 1.00 25.23 ? 357 MET B CE 1 ATOM 4514 N N . ARG B 1 168 ? 82.657 39.990 65.708 1.00 20.69 ? 358 ARG B N 1 ATOM 4515 C CA . ARG B 1 168 ? 82.237 39.392 66.971 1.00 17.14 ? 358 ARG B CA 1 ATOM 4516 C C . ARG B 1 168 ? 80.879 40.031 67.264 1.00 16.32 ? 358 ARG B C 1 ATOM 4517 O O . ARG B 1 168 ? 80.658 41.198 66.944 1.00 12.44 ? 358 ARG B O 1 ATOM 4518 C CB . ARG B 1 168 ? 83.216 39.717 68.105 1.00 14.75 ? 358 ARG B CB 1 ATOM 4519 C CG . ARG B 1 168 ? 84.525 38.935 68.083 1.00 20.32 ? 358 ARG B CG 1 ATOM 4520 C CD . ARG B 1 168 ? 85.018 38.707 69.512 1.00 31.98 ? 358 ARG B CD 1 ATOM 4521 N NE . ARG B 1 168 ? 86.394 38.215 69.610 1.00 38.50 ? 358 ARG B NE 1 ATOM 4522 C CZ . ARG B 1 168 ? 86.847 37.095 69.051 1.00 43.24 ? 358 ARG B CZ 1 ATOM 4523 N NH1 . ARG B 1 168 ? 88.114 36.742 69.212 1.00 39.75 ? 358 ARG B NH1 1 ATOM 4524 N NH2 . ARG B 1 168 ? 86.044 36.332 68.321 1.00 50.75 ? 358 ARG B NH2 1 ATOM 4525 N N . PRO B 1 169 ? 79.952 39.277 67.875 1.00 21.31 ? 359 PRO B N 1 ATOM 4526 C CA . PRO B 1 169 ? 78.618 39.800 68.191 1.00 22.89 ? 359 PRO B CA 1 ATOM 4527 C C . PRO B 1 169 ? 78.586 41.144 68.923 1.00 23.19 ? 359 PRO B C 1 ATOM 4528 O O . PRO B 1 169 ? 77.579 41.847 68.886 1.00 29.35 ? 359 PRO B O 1 ATOM 4529 C CB . PRO B 1 169 ? 77.984 38.666 68.997 1.00 18.24 ? 359 PRO B CB 1 ATOM 4530 C CG . PRO B 1 169 ? 79.164 37.968 69.603 1.00 25.98 ? 359 PRO B CG 1 ATOM 4531 C CD . PRO B 1 169 ? 80.139 37.939 68.461 1.00 23.74 ? 359 PRO B CD 1 ATOM 4532 N N . GLU B 1 170 ? 79.678 41.502 69.586 1.00 21.13 ? 360 GLU B N 1 ATOM 4533 C CA . GLU B 1 170 ? 79.739 42.779 70.291 1.00 22.25 ? 360 GLU B CA 1 ATOM 4534 C C . GLU B 1 170 ? 81.147 43.366 70.323 1.00 22.66 ? 360 GLU B C 1 ATOM 4535 O O . GLU B 1 170 ? 82.138 42.651 70.500 1.00 22.27 ? 360 GLU B O 1 ATOM 4536 C CB . GLU B 1 170 ? 79.186 42.637 71.713 1.00 22.98 ? 360 GLU B CB 1 ATOM 4537 C CG . GLU B 1 170 ? 79.531 41.339 72.409 1.00 35.59 ? 360 GLU B CG 1 ATOM 4538 C CD . GLU B 1 170 ? 78.291 40.546 72.780 1.00 43.83 ? 360 GLU B CD 1 ATOM 4539 O OE1 . GLU B 1 170 ? 77.439 41.081 73.519 1.00 46.49 ? 360 GLU B OE1 1 ATOM 4540 O OE2 . GLU B 1 170 ? 78.166 39.388 72.331 1.00 50.30 ? 360 GLU B OE2 1 ATOM 4541 N N . ILE B 1 171 ? 81.225 44.680 70.141 1.00 23.75 ? 361 ILE B N 1 ATOM 4542 C CA . ILE B 1 171 ? 82.500 45.386 70.127 1.00 25.96 ? 361 ILE B CA 1 ATOM 4543 C C . ILE B 1 171 ? 83.295 45.213 71.421 1.00 23.99 ? 361 ILE B C 1 ATOM 4544 O O . ILE B 1 171 ? 82.769 45.405 72.515 1.00 25.45 ? 361 ILE B O 1 ATOM 4545 C CB . ILE B 1 171 ? 82.280 46.888 69.872 1.00 26.01 ? 361 ILE B CB 1 ATOM 4546 C CG1 . ILE B 1 171 ? 83.626 47.592 69.710 1.00 25.59 ? 361 ILE B CG1 1 ATOM 4547 C CG2 . ILE B 1 171 ? 81.495 47.501 71.021 1.00 32.56 ? 361 ILE B CG2 1 ATOM 4548 C CD1 . ILE B 1 171 ? 83.505 49.046 69.358 1.00 27.97 ? 361 ILE B CD1 1 ATOM 4549 N N . SER B 1 172 ? 84.566 44.853 71.292 1.00 24.15 ? 362 SER B N 1 ATOM 4550 C CA . SER B 1 172 ? 85.417 44.663 72.462 1.00 31.47 ? 362 SER B CA 1 ATOM 4551 C C . SER B 1 172 ? 86.092 45.964 72.867 1.00 34.91 ? 362 SER B C 1 ATOM 4552 O O . SER B 1 172 ? 86.150 46.916 72.089 1.00 33.73 ? 362 SER B O 1 ATOM 4553 C CB . SER B 1 172 ? 86.488 43.604 72.184 1.00 31.54 ? 362 SER B CB 1 ATOM 4554 O OG . SER B 1 172 ? 87.363 44.022 71.153 1.00 29.86 ? 362 SER B OG 1 ATOM 4555 N N . PRO B 1 173 ? 86.607 46.026 74.103 1.00 39.52 ? 363 PRO B N 1 ATOM 4556 C CA . PRO B 1 173 ? 87.279 47.234 74.583 1.00 39.66 ? 363 PRO B CA 1 ATOM 4557 C C . PRO B 1 173 ? 88.713 47.255 74.073 1.00 40.96 ? 363 PRO B C 1 ATOM 4558 O O . PRO B 1 173 ? 89.429 48.242 74.232 1.00 44.25 ? 363 PRO B O 1 ATOM 4559 C CB . PRO B 1 173 ? 87.204 47.078 76.095 1.00 40.18 ? 363 PRO B CB 1 ATOM 4560 C CG . PRO B 1 173 ? 87.405 45.601 76.263 1.00 39.82 ? 363 PRO B CG 1 ATOM 4561 C CD . PRO B 1 173 ? 86.513 45.017 75.176 1.00 41.32 ? 363 PRO B CD 1 ATOM 4562 N N . GLU B 1 174 ? 89.114 46.150 73.453 1.00 41.00 ? 364 GLU B N 1 ATOM 4563 C CA . GLU B 1 174 ? 90.459 45.991 72.912 1.00 38.58 ? 364 GLU B CA 1 ATOM 4564 C C . GLU B 1 174 ? 90.327 45.598 71.438 1.00 33.02 ? 364 GLU B C 1 ATOM 4565 O O . GLU B 1 174 ? 90.823 44.553 71.017 1.00 30.85 ? 364 GLU B O 1 ATOM 4566 C CB . GLU B 1 174 ? 91.178 44.891 73.694 1.00 47.42 ? 364 GLU B CB 1 ATOM 4567 C CG . GLU B 1 174 ? 92.669 44.776 73.442 1.00 63.26 ? 364 GLU B CG 1 ATOM 4568 C CD . GLU B 1 174 ? 93.292 43.628 74.220 1.00 69.83 ? 364 GLU B CD 1 ATOM 4569 O OE1 . GLU B 1 174 ? 93.105 43.577 75.457 1.00 69.25 ? 364 GLU B OE1 1 ATOM 4570 O OE2 . GLU B 1 174 ? 93.969 42.779 73.595 1.00 74.02 ? 364 GLU B OE2 1 ATOM 4571 N N . PRO B 1 175 ? 89.664 46.449 70.635 1.00 29.55 ? 365 PRO B N 1 ATOM 4572 C CA . PRO B 1 175 ? 89.415 46.258 69.199 1.00 24.43 ? 365 PRO B CA 1 ATOM 4573 C C . PRO B 1 175 ? 90.641 45.978 68.338 1.00 21.76 ? 365 PRO B C 1 ATOM 4574 O O . PRO B 1 175 ? 91.722 46.522 68.571 1.00 19.13 ? 365 PRO B O 1 ATOM 4575 C CB . PRO B 1 175 ? 88.740 47.568 68.783 1.00 21.49 ? 365 PRO B CB 1 ATOM 4576 C CG . PRO B 1 175 ? 88.143 48.080 70.047 1.00 27.01 ? 365 PRO B CG 1 ATOM 4577 C CD . PRO B 1 175 ? 89.219 47.790 71.051 1.00 26.67 ? 365 PRO B CD 1 ATOM 4578 N N . SER B 1 176 ? 90.454 45.133 67.331 1.00 16.83 ? 366 SER B N 1 ATOM 4579 C CA . SER B 1 176 ? 91.520 44.796 66.402 1.00 20.20 ? 366 SER B CA 1 ATOM 4580 C C . SER B 1 176 ? 90.989 45.064 65.000 1.00 19.02 ? 366 SER B C 1 ATOM 4581 O O . SER B 1 176 ? 89.783 45.125 64.791 1.00 23.86 ? 366 SER B O 1 ATOM 4582 C CB . SER B 1 176 ? 91.920 43.325 66.525 1.00 17.79 ? 366 SER B CB 1 ATOM 4583 O OG . SER B 1 176 ? 91.077 42.499 65.740 1.00 24.58 ? 366 SER B OG 1 ATOM 4584 N N . THR B 1 177 ? 91.894 45.213 64.043 1.00 21.67 ? 367 THR B N 1 ATOM 4585 C CA . THR B 1 177 ? 91.526 45.492 62.659 1.00 24.11 ? 367 THR B CA 1 ATOM 4586 C C . THR B 1 177 ? 91.319 44.232 61.817 1.00 23.84 ? 367 THR B C 1 ATOM 4587 O O . THR B 1 177 ? 91.090 44.321 60.610 1.00 18.68 ? 367 THR B O 1 ATOM 4588 C CB . THR B 1 177 ? 92.621 46.324 61.982 1.00 24.74 ? 367 THR B CB 1 ATOM 4589 O OG1 . THR B 1 177 ? 93.877 45.643 62.125 1.00 27.04 ? 367 THR B OG1 1 ATOM 4590 C CG2 . THR B 1 177 ? 92.721 47.707 62.616 1.00 16.04 ? 367 THR B CG2 1 ATOM 4591 N N . PHE B 1 178 ? 91.376 43.064 62.452 1.00 25.69 ? 368 PHE B N 1 ATOM 4592 C CA . PHE B 1 178 ? 91.251 41.804 61.725 1.00 23.21 ? 368 PHE B CA 1 ATOM 4593 C C . PHE B 1 178 ? 89.875 41.163 61.617 1.00 19.87 ? 368 PHE B C 1 ATOM 4594 O O . PHE B 1 178 ? 89.112 41.126 62.577 1.00 20.05 ? 368 PHE B O 1 ATOM 4595 C CB . PHE B 1 178 ? 92.214 40.777 62.319 1.00 26.29 ? 368 PHE B CB 1 ATOM 4596 C CG . PHE B 1 178 ? 93.611 41.287 62.486 1.00 30.54 ? 368 PHE B CG 1 ATOM 4597 C CD1 . PHE B 1 178 ? 94.161 41.439 63.754 1.00 32.49 ? 368 PHE B CD1 1 ATOM 4598 C CD2 . PHE B 1 178 ? 94.379 41.626 61.375 1.00 36.65 ? 368 PHE B CD2 1 ATOM 4599 C CE1 . PHE B 1 178 ? 95.458 41.921 63.918 1.00 34.50 ? 368 PHE B CE1 1 ATOM 4600 C CE2 . PHE B 1 178 ? 95.678 42.111 61.525 1.00 36.33 ? 368 PHE B CE2 1 ATOM 4601 C CZ . PHE B 1 178 ? 96.219 42.258 62.801 1.00 37.03 ? 368 PHE B CZ 1 ATOM 4602 N N . PHE B 1 179 ? 89.591 40.648 60.423 1.00 21.34 ? 369 PHE B N 1 ATOM 4603 C CA . PHE B 1 179 ? 88.349 39.943 60.114 1.00 19.49 ? 369 PHE B CA 1 ATOM 4604 C C . PHE B 1 179 ? 88.669 38.464 60.291 1.00 19.93 ? 369 PHE B C 1 ATOM 4605 O O . PHE B 1 179 ? 89.756 38.020 59.922 1.00 25.92 ? 369 PHE B O 1 ATOM 4606 C CB . PHE B 1 179 ? 87.943 40.190 58.658 1.00 20.46 ? 369 PHE B CB 1 ATOM 4607 C CG . PHE B 1 179 ? 86.914 41.268 58.484 1.00 20.38 ? 369 PHE B CG 1 ATOM 4608 C CD1 . PHE B 1 179 ? 85.610 41.084 58.941 1.00 15.15 ? 369 PHE B CD1 1 ATOM 4609 C CD2 . PHE B 1 179 ? 87.242 42.461 57.850 1.00 14.18 ? 369 PHE B CD2 1 ATOM 4610 C CE1 . PHE B 1 179 ? 84.649 42.070 58.768 1.00 17.67 ? 369 PHE B CE1 1 ATOM 4611 C CE2 . PHE B 1 179 ? 86.284 43.460 57.671 1.00 18.18 ? 369 PHE B CE2 1 ATOM 4612 C CZ . PHE B 1 179 ? 84.986 43.263 58.131 1.00 18.71 ? 369 PHE B CZ 1 ATOM 4613 N N . SER B 1 180 ? 87.737 37.698 60.848 1.00 20.59 ? 370 SER B N 1 ATOM 4614 C CA . SER B 1 180 ? 87.970 36.269 61.059 1.00 18.86 ? 370 SER B CA 1 ATOM 4615 C C . SER B 1 180 ? 88.030 35.539 59.725 1.00 19.93 ? 370 SER B C 1 ATOM 4616 O O . SER B 1 180 ? 87.696 36.107 58.683 1.00 21.68 ? 370 SER B O 1 ATOM 4617 C CB . SER B 1 180 ? 86.850 35.660 61.903 1.00 19.50 ? 370 SER B CB 1 ATOM 4618 O OG . SER B 1 180 ? 85.679 35.473 61.127 1.00 13.47 ? 370 SER B OG 1 ATOM 4619 N N . ASN B 1 181 ? 88.459 34.281 59.753 1.00 21.22 ? 371 ASN B N 1 ATOM 4620 C CA . ASN B 1 181 ? 88.521 33.494 58.531 1.00 20.43 ? 371 ASN B CA 1 ATOM 4621 C C . ASN B 1 181 ? 87.090 33.217 58.072 1.00 24.50 ? 371 ASN B C 1 ATOM 4622 O O . ASN B 1 181 ? 86.817 33.134 56.873 1.00 25.54 ? 371 ASN B O 1 ATOM 4623 C CB . ASN B 1 181 ? 89.302 32.194 58.766 1.00 22.45 ? 371 ASN B CB 1 ATOM 4624 C CG . ASN B 1 181 ? 88.722 31.343 59.876 1.00 22.57 ? 371 ASN B CG 1 ATOM 4625 O OD1 . ASN B 1 181 ? 88.183 31.856 60.857 1.00 19.27 ? 371 ASN B OD1 1 ATOM 4626 N ND2 . ASN B 1 181 ? 88.864 30.029 59.735 1.00 31.02 ? 371 ASN B ND2 1 ATOM 4627 N N . CYS B 1 182 ? 86.173 33.107 59.033 1.00 26.20 ? 372 CYS B N 1 ATOM 4628 C CA . CYS B 1 182 ? 84.763 32.875 58.729 1.00 27.01 ? 372 CYS B CA 1 ATOM 4629 C C . CYS B 1 182 ? 84.211 34.054 57.924 1.00 26.23 ? 372 CYS B C 1 ATOM 4630 O O . CYS B 1 182 ? 83.649 33.868 56.844 1.00 28.45 ? 372 CYS B O 1 ATOM 4631 C CB . CYS B 1 182 ? 83.946 32.718 60.018 1.00 26.82 ? 372 CYS B CB 1 ATOM 4632 S SG . CYS B 1 182 ? 84.315 31.225 60.994 1.00 28.80 ? 372 CYS B SG 1 ATOM 4633 N N . SER B 1 183 ? 84.375 35.262 58.462 1.00 19.16 ? 373 SER B N 1 ATOM 4634 C CA . SER B 1 183 ? 83.907 36.475 57.799 1.00 17.70 ? 373 SER B CA 1 ATOM 4635 C C . SER B 1 183 ? 84.351 36.516 56.340 1.00 18.51 ? 373 SER B C 1 ATOM 4636 O O . SER B 1 183 ? 83.557 36.816 55.449 1.00 17.59 ? 373 SER B O 1 ATOM 4637 C CB . SER B 1 183 ? 84.439 37.713 58.521 1.00 18.08 ? 373 SER B CB 1 ATOM 4638 O OG . SER B 1 183 ? 83.974 37.772 59.857 1.00 21.80 ? 373 SER B OG 1 ATOM 4639 N N . TYR B 1 184 ? 85.623 36.211 56.105 1.00 17.16 ? 374 TYR B N 1 ATOM 4640 C CA . TYR B 1 184 ? 86.186 36.208 54.759 1.00 23.91 ? 374 TYR B CA 1 ATOM 4641 C C . TYR B 1 184 ? 85.391 35.324 53.798 1.00 26.36 ? 374 TYR B C 1 ATOM 4642 O O . TYR B 1 184 ? 84.863 35.796 52.788 1.00 26.41 ? 374 TYR B O 1 ATOM 4643 C CB . TYR B 1 184 ? 87.631 35.714 54.804 1.00 26.28 ? 374 TYR B CB 1 ATOM 4644 C CG . TYR B 1 184 ? 88.331 35.749 53.467 1.00 28.34 ? 374 TYR B CG 1 ATOM 4645 C CD1 . TYR B 1 184 ? 88.873 36.936 52.975 1.00 36.66 ? 374 TYR B CD1 1 ATOM 4646 C CD2 . TYR B 1 184 ? 88.449 34.598 52.689 1.00 29.41 ? 374 TYR B CD2 1 ATOM 4647 C CE1 . TYR B 1 184 ? 89.519 36.978 51.739 1.00 34.69 ? 374 TYR B CE1 1 ATOM 4648 C CE2 . TYR B 1 184 ? 89.092 34.629 51.450 1.00 31.84 ? 374 TYR B CE2 1 ATOM 4649 C CZ . TYR B 1 184 ? 89.625 35.822 50.985 1.00 32.97 ? 374 TYR B CZ 1 ATOM 4650 O OH . TYR B 1 184 ? 90.262 35.865 49.767 1.00 34.82 ? 374 TYR B OH 1 ATOM 4651 N N . PHE B 1 185 ? 85.321 34.036 54.117 1.00 27.11 ? 375 PHE B N 1 ATOM 4652 C CA . PHE B 1 185 ? 84.605 33.068 53.290 1.00 28.83 ? 375 PHE B CA 1 ATOM 4653 C C . PHE B 1 185 ? 83.147 33.451 53.028 1.00 27.65 ? 375 PHE B C 1 ATOM 4654 O O . PHE B 1 185 ? 82.669 33.351 51.895 1.00 27.40 ? 375 PHE B O 1 ATOM 4655 C CB . PHE B 1 185 ? 84.685 31.683 53.942 1.00 28.89 ? 375 PHE B CB 1 ATOM 4656 C CG . PHE B 1 185 ? 86.076 31.103 53.965 1.00 30.28 ? 375 PHE B CG 1 ATOM 4657 C CD1 . PHE B 1 185 ? 86.517 30.355 55.052 1.00 32.94 ? 375 PHE B CD1 1 ATOM 4658 C CD2 . PHE B 1 185 ? 86.943 31.293 52.890 1.00 30.45 ? 375 PHE B CD2 1 ATOM 4659 C CE1 . PHE B 1 185 ? 87.801 29.805 55.068 1.00 32.28 ? 375 PHE B CE1 1 ATOM 4660 C CE2 . PHE B 1 185 ? 88.226 30.746 52.897 1.00 28.53 ? 375 PHE B CE2 1 ATOM 4661 C CZ . PHE B 1 185 ? 88.655 30.003 53.988 1.00 27.62 ? 375 PHE B CZ 1 ATOM 4662 N N . GLU B 1 186 ? 82.438 33.881 54.067 1.00 25.47 ? 376 GLU B N 1 ATOM 4663 C CA . GLU B 1 186 ? 81.047 34.282 53.905 1.00 27.33 ? 376 GLU B CA 1 ATOM 4664 C C . GLU B 1 186 ? 80.967 35.510 53.017 1.00 25.55 ? 376 GLU B C 1 ATOM 4665 O O . GLU B 1 186 ? 80.072 35.628 52.181 1.00 26.88 ? 376 GLU B O 1 ATOM 4666 C CB . GLU B 1 186 ? 80.405 34.590 55.257 1.00 32.07 ? 376 GLU B CB 1 ATOM 4667 C CG . GLU B 1 186 ? 79.913 33.364 55.992 1.00 43.92 ? 376 GLU B CG 1 ATOM 4668 C CD . GLU B 1 186 ? 79.010 33.715 57.153 1.00 51.24 ? 376 GLU B CD 1 ATOM 4669 O OE1 . GLU B 1 186 ? 78.403 32.791 57.738 1.00 53.97 ? 376 GLU B OE1 1 ATOM 4670 O OE2 . GLU B 1 186 ? 78.913 34.917 57.479 1.00 53.21 ? 376 GLU B OE2 1 ATOM 4671 N N . CYS B 1 187 ? 81.911 36.425 53.209 1.00 23.29 ? 377 CYS B N 1 ATOM 4672 C CA . CYS B 1 187 ? 81.960 37.647 52.423 1.00 25.30 ? 377 CYS B CA 1 ATOM 4673 C C . CYS B 1 187 ? 82.022 37.319 50.936 1.00 25.04 ? 377 CYS B C 1 ATOM 4674 O O . CYS B 1 187 ? 81.273 37.878 50.131 1.00 22.40 ? 377 CYS B O 1 ATOM 4675 C CB . CYS B 1 187 ? 83.184 38.474 52.815 1.00 28.27 ? 377 CYS B CB 1 ATOM 4676 S SG . CYS B 1 187 ? 83.397 39.979 51.842 1.00 34.54 ? 377 CYS B SG 1 ATOM 4677 N N . TRP B 1 188 ? 82.916 36.407 50.571 1.00 24.54 ? 378 TRP B N 1 ATOM 4678 C CA . TRP B 1 188 ? 83.050 36.029 49.175 1.00 26.92 ? 378 TRP B CA 1 ATOM 4679 C C . TRP B 1 188 ? 81.961 35.075 48.718 1.00 28.88 ? 378 TRP B C 1 ATOM 4680 O O . TRP B 1 188 ? 81.656 34.998 47.529 1.00 28.88 ? 378 TRP B O 1 ATOM 4681 C CB . TRP B 1 188 ? 84.436 35.444 48.917 1.00 25.17 ? 378 TRP B CB 1 ATOM 4682 C CG . TRP B 1 188 ? 85.477 36.508 48.958 1.00 29.75 ? 378 TRP B CG 1 ATOM 4683 C CD1 . TRP B 1 188 ? 86.314 36.803 49.995 1.00 29.22 ? 378 TRP B CD1 1 ATOM 4684 C CD2 . TRP B 1 188 ? 85.725 37.493 47.949 1.00 31.09 ? 378 TRP B CD2 1 ATOM 4685 N NE1 . TRP B 1 188 ? 87.065 37.914 49.696 1.00 29.98 ? 378 TRP B NE1 1 ATOM 4686 C CE2 . TRP B 1 188 ? 86.723 38.358 48.445 1.00 30.86 ? 378 TRP B CE2 1 ATOM 4687 C CE3 . TRP B 1 188 ? 85.198 37.730 46.672 1.00 34.62 ? 378 TRP B CE3 1 ATOM 4688 C CZ2 . TRP B 1 188 ? 87.207 39.443 47.709 1.00 33.19 ? 378 TRP B CZ2 1 ATOM 4689 C CZ3 . TRP B 1 188 ? 85.679 38.810 45.940 1.00 33.27 ? 378 TRP B CZ3 1 ATOM 4690 C CH2 . TRP B 1 188 ? 86.674 39.652 46.462 1.00 32.73 ? 378 TRP B CH2 1 ATOM 4691 N N . ASP B 1 189 ? 81.366 34.350 49.658 1.00 29.48 ? 379 ASP B N 1 ATOM 4692 C CA . ASP B 1 189 ? 80.293 33.445 49.295 1.00 31.60 ? 379 ASP B CA 1 ATOM 4693 C C . ASP B 1 189 ? 79.147 34.325 48.828 1.00 28.81 ? 379 ASP B C 1 ATOM 4694 O O . ASP B 1 189 ? 78.362 33.946 47.960 1.00 31.20 ? 379 ASP B O 1 ATOM 4695 C CB . ASP B 1 189 ? 79.851 32.610 50.494 1.00 38.97 ? 379 ASP B CB 1 ATOM 4696 C CG . ASP B 1 189 ? 78.659 31.732 50.174 1.00 44.78 ? 379 ASP B CG 1 ATOM 4697 O OD1 . ASP B 1 189 ? 78.740 30.954 49.201 1.00 50.69 ? 379 ASP B OD1 1 ATOM 4698 O OD2 . ASP B 1 189 ? 77.640 31.821 50.892 1.00 50.42 ? 379 ASP B OD2 1 ATOM 4699 N N . PHE B 1 190 ? 79.063 35.514 49.413 1.00 27.53 ? 380 PHE B N 1 ATOM 4700 C CA . PHE B 1 190 ? 78.022 36.465 49.053 1.00 25.77 ? 380 PHE B CA 1 ATOM 4701 C C . PHE B 1 190 ? 78.327 37.083 47.690 1.00 28.83 ? 380 PHE B C 1 ATOM 4702 O O . PHE B 1 190 ? 77.459 37.157 46.820 1.00 25.31 ? 380 PHE B O 1 ATOM 4703 C CB . PHE B 1 190 ? 77.929 37.571 50.100 1.00 20.38 ? 380 PHE B CB 1 ATOM 4704 C CG . PHE B 1 190 ? 76.936 38.636 49.755 1.00 17.46 ? 380 PHE B CG 1 ATOM 4705 C CD1 . PHE B 1 190 ? 75.573 38.402 49.890 1.00 14.48 ? 380 PHE B CD1 1 ATOM 4706 C CD2 . PHE B 1 190 ? 77.363 39.864 49.254 1.00 15.72 ? 380 PHE B CD2 1 ATOM 4707 C CE1 . PHE B 1 190 ? 74.643 39.376 49.529 1.00 17.27 ? 380 PHE B CE1 1 ATOM 4708 C CE2 . PHE B 1 190 ? 76.444 40.845 48.890 1.00 14.15 ? 380 PHE B CE2 1 ATOM 4709 C CZ . PHE B 1 190 ? 75.080 40.600 49.028 1.00 20.63 ? 380 PHE B CZ 1 ATOM 4710 N N . ILE B 1 191 ? 79.569 37.525 47.516 1.00 30.62 ? 381 ILE B N 1 ATOM 4711 C CA . ILE B 1 191 ? 80.003 38.140 46.270 1.00 33.24 ? 381 ILE B CA 1 ATOM 4712 C C . ILE B 1 191 ? 79.875 37.206 45.069 1.00 34.70 ? 381 ILE B C 1 ATOM 4713 O O . ILE B 1 191 ? 79.402 37.617 44.009 1.00 37.28 ? 381 ILE B O 1 ATOM 4714 C CB . ILE B 1 191 ? 81.465 38.624 46.378 1.00 34.96 ? 381 ILE B CB 1 ATOM 4715 C CG1 . ILE B 1 191 ? 81.556 39.745 47.416 1.00 34.05 ? 381 ILE B CG1 1 ATOM 4716 C CG2 . ILE B 1 191 ? 81.965 39.105 45.024 1.00 36.81 ? 381 ILE B CG2 1 ATOM 4717 C CD1 . ILE B 1 191 ? 82.956 40.282 47.626 1.00 27.22 ? 381 ILE B CD1 1 ATOM 4718 N N . MET B 1 192 ? 80.292 35.953 45.232 1.00 35.93 ? 382 MET B N 1 ATOM 4719 C CA . MET B 1 192 ? 80.219 34.981 44.144 1.00 36.39 ? 382 MET B CA 1 ATOM 4720 C C . MET B 1 192 ? 78.786 34.559 43.807 1.00 35.73 ? 382 MET B C 1 ATOM 4721 O O . MET B 1 192 ? 78.370 34.662 42.653 1.00 32.52 ? 382 MET B O 1 ATOM 4722 C CB . MET B 1 192 ? 81.057 33.744 44.480 1.00 42.62 ? 382 MET B CB 1 ATOM 4723 C CG . MET B 1 192 ? 82.539 34.034 44.717 1.00 50.96 ? 382 MET B CG 1 ATOM 4724 S SD . MET B 1 192 ? 83.383 34.769 43.291 1.00 58.20 ? 382 MET B SD 1 ATOM 4725 C CE . MET B 1 192 ? 84.041 33.298 42.483 1.00 52.21 ? 382 MET B CE 1 ATOM 4726 N N . ASN B 1 193 ? 78.036 34.085 44.800 1.00 34.27 ? 383 ASN B N 1 ATOM 4727 C CA . ASN B 1 193 ? 76.652 33.661 44.572 1.00 37.01 ? 383 ASN B CA 1 ATOM 4728 C C . ASN B 1 193 ? 75.803 34.838 44.119 1.00 36.98 ? 383 ASN B C 1 ATOM 4729 O O . ASN B 1 193 ? 75.392 34.906 42.963 1.00 39.62 ? 383 ASN B O 1 ATOM 4730 C CB . ASN B 1 193 ? 76.055 33.052 45.840 1.00 41.92 ? 383 ASN B CB 1 ATOM 4731 C CG . ASN B 1 193 ? 76.553 31.645 46.097 1.00 48.03 ? 383 ASN B CG 1 ATOM 4732 O OD1 . ASN B 1 193 ? 77.756 31.409 46.215 1.00 50.28 ? 383 ASN B OD1 1 ATOM 4733 N ND2 . ASN B 1 193 ? 75.624 30.698 46.183 1.00 53.07 ? 383 ASN B ND2 1 ATOM 4734 N N . HIS B 1 194 ? 75.522 35.760 45.032 1.00 40.82 ? 384 HIS B N 1 ATOM 4735 C CA . HIS B 1 194 ? 74.755 36.944 44.670 1.00 43.07 ? 384 HIS B CA 1 ATOM 4736 C C . HIS B 1 194 ? 75.746 37.769 43.861 1.00 43.15 ? 384 HIS B C 1 ATOM 4737 O O . HIS B 1 194 ? 76.891 37.355 43.688 1.00 45.39 ? 384 HIS B O 1 ATOM 4738 C CB . HIS B 1 194 ? 74.315 37.703 45.921 1.00 45.35 ? 384 HIS B CB 1 ATOM 4739 C CG . HIS B 1 194 ? 73.453 36.896 46.840 1.00 49.97 ? 384 HIS B CG 1 ATOM 4740 N ND1 . HIS B 1 194 ? 73.887 35.729 47.432 1.00 50.83 ? 384 HIS B ND1 1 ATOM 4741 C CD2 . HIS B 1 194 ? 72.181 37.082 47.265 1.00 52.45 ? 384 HIS B CD2 1 ATOM 4742 C CE1 . HIS B 1 194 ? 72.919 35.231 48.182 1.00 51.00 ? 384 HIS B CE1 1 ATOM 4743 N NE2 . HIS B 1 194 ? 71.873 36.034 48.098 1.00 51.47 ? 384 HIS B NE2 1 ATOM 4744 N N . ASN B 1 195 ? 75.342 38.927 43.362 1.00 41.44 ? 385 ASN B N 1 ATOM 4745 C CA . ASN B 1 195 ? 76.290 39.697 42.578 1.00 44.20 ? 385 ASN B CA 1 ATOM 4746 C C . ASN B 1 195 ? 76.279 41.185 42.894 1.00 46.53 ? 385 ASN B C 1 ATOM 4747 O O . ASN B 1 195 ? 75.439 41.933 42.391 1.00 49.02 ? 385 ASN B O 1 ATOM 4748 C CB . ASN B 1 195 ? 76.025 39.477 41.087 1.00 49.48 ? 385 ASN B CB 1 ATOM 4749 C CG . ASN B 1 195 ? 77.272 39.657 40.237 1.00 51.20 ? 385 ASN B CG 1 ATOM 4750 O OD1 . ASN B 1 195 ? 77.202 39.646 39.006 1.00 52.87 ? 385 ASN B OD1 1 ATOM 4751 N ND2 . ASN B 1 195 ? 78.420 39.813 40.889 1.00 47.07 ? 385 ASN B ND2 1 ATOM 4752 N N . PRO B 1 196 ? 77.207 41.631 43.756 1.00 45.62 ? 386 PRO B N 1 ATOM 4753 C CA . PRO B 1 196 ? 77.301 43.044 44.134 1.00 43.46 ? 386 PRO B CA 1 ATOM 4754 C C . PRO B 1 196 ? 77.856 43.853 42.959 1.00 41.07 ? 386 PRO B C 1 ATOM 4755 O O . PRO B 1 196 ? 78.815 44.607 43.100 1.00 42.48 ? 386 PRO B O 1 ATOM 4756 C CB . PRO B 1 196 ? 78.258 43.018 45.324 1.00 45.66 ? 386 PRO B CB 1 ATOM 4757 C CG . PRO B 1 196 ? 78.061 41.646 45.897 1.00 44.39 ? 386 PRO B CG 1 ATOM 4758 C CD . PRO B 1 196 ? 78.022 40.800 44.657 1.00 45.17 ? 386 PRO B CD 1 ATOM 4759 N N . GLU B 1 197 ? 77.233 43.670 41.800 1.00 39.04 ? 387 GLU B N 1 ATOM 4760 C CA . GLU B 1 197 ? 77.608 44.333 40.558 1.00 37.62 ? 387 GLU B CA 1 ATOM 4761 C C . GLU B 1 197 ? 78.241 45.717 40.741 1.00 34.28 ? 387 GLU B C 1 ATOM 4762 O O . GLU B 1 197 ? 79.305 46.001 40.191 1.00 31.61 ? 387 GLU B O 1 ATOM 4763 C CB . GLU B 1 197 ? 76.366 44.454 39.667 1.00 43.55 ? 387 GLU B CB 1 ATOM 4764 C CG . GLU B 1 197 ? 76.638 44.773 38.197 1.00 54.96 ? 387 GLU B CG 1 ATOM 4765 C CD . GLU B 1 197 ? 76.972 43.538 37.368 1.00 59.48 ? 387 GLU B CD 1 ATOM 4766 O OE1 . GLU B 1 197 ? 76.129 42.616 37.295 1.00 54.64 ? 387 GLU B OE1 1 ATOM 4767 O OE2 . GLU B 1 197 ? 78.078 43.492 36.785 1.00 62.50 ? 387 GLU B OE2 1 ATOM 4768 N N . CYS B 1 198 ? 77.588 46.564 41.530 1.00 29.68 ? 388 CYS B N 1 ATOM 4769 C CA . CYS B 1 198 ? 78.045 47.932 41.755 1.00 23.71 ? 388 CYS B CA 1 ATOM 4770 C C . CYS B 1 198 ? 79.373 48.125 42.486 1.00 23.63 ? 388 CYS B C 1 ATOM 4771 O O . CYS B 1 198 ? 79.853 49.254 42.597 1.00 22.37 ? 388 CYS B O 1 ATOM 4772 C CB . CYS B 1 198 ? 76.959 48.717 42.489 1.00 26.82 ? 388 CYS B CB 1 ATOM 4773 S SG . CYS B 1 198 ? 77.088 48.664 44.304 1.00 40.04 ? 388 CYS B SG 1 ATOM 4774 N N . ILE B 1 199 ? 79.978 47.050 42.980 1.00 25.16 ? 389 ILE B N 1 ATOM 4775 C CA . ILE B 1 199 ? 81.248 47.192 43.690 1.00 22.69 ? 389 ILE B CA 1 ATOM 4776 C C . ILE B 1 199 ? 82.464 46.745 42.880 1.00 24.56 ? 389 ILE B C 1 ATOM 4777 O O . ILE B 1 199 ? 83.550 46.546 43.435 1.00 25.59 ? 389 ILE B O 1 ATOM 4778 C CB . ILE B 1 199 ? 81.238 46.422 45.033 1.00 23.00 ? 389 ILE B CB 1 ATOM 4779 C CG1 . ILE B 1 199 ? 81.125 44.916 44.783 1.00 16.42 ? 389 ILE B CG1 1 ATOM 4780 C CG2 . ILE B 1 199 ? 80.081 46.913 45.897 1.00 25.08 ? 389 ILE B CG2 1 ATOM 4781 C CD1 . ILE B 1 199 ? 81.301 44.074 46.035 1.00 9.31 ? 389 ILE B CD1 1 ATOM 4782 N N . LEU B 1 200 ? 82.288 46.604 41.569 1.00 22.45 ? 390 LEU B N 1 ATOM 4783 C CA . LEU B 1 200 ? 83.382 46.181 40.700 1.00 18.90 ? 390 LEU B CA 1 ATOM 4784 C C . LEU B 1 200 ? 84.302 47.320 40.270 1.00 17.52 ? 390 LEU B C 1 ATOM 4785 O O . LEU B 1 200 ? 85.522 47.181 40.310 1.00 22.66 ? 390 LEU B O 1 ATOM 4786 C CB . LEU B 1 200 ? 82.827 45.483 39.456 1.00 15.81 ? 390 LEU B CB 1 ATOM 4787 C CG . LEU B 1 200 ? 82.156 44.129 39.699 1.00 21.39 ? 390 LEU B CG 1 ATOM 4788 C CD1 . LEU B 1 200 ? 81.435 43.653 38.444 1.00 17.40 ? 390 LEU B CD1 1 ATOM 4789 C CD2 . LEU B 1 200 ? 83.209 43.128 40.127 1.00 19.04 ? 390 LEU B CD2 1 ATOM 4790 N N . ASN B 1 201 ? 83.717 48.445 39.869 1.00 14.37 ? 391 ASN B N 1 ATOM 4791 C CA . ASN B 1 201 ? 84.488 49.594 39.399 1.00 16.65 ? 391 ASN B CA 1 ATOM 4792 C C . ASN B 1 201 ? 85.451 50.229 40.398 1.00 18.71 ? 391 ASN B C 1 ATOM 4793 O O . ASN B 1 201 ? 85.113 50.446 41.560 1.00 19.01 ? 391 ASN B O 1 ATOM 4794 C CB . ASN B 1 201 ? 83.550 50.685 38.883 1.00 17.21 ? 391 ASN B CB 1 ATOM 4795 C CG . ASN B 1 201 ? 82.655 51.246 39.971 1.00 24.96 ? 391 ASN B CG 1 ATOM 4796 O OD1 . ASN B 1 201 ? 82.065 52.314 39.812 1.00 27.27 ? 391 ASN B OD1 1 ATOM 4797 N ND2 . ASN B 1 201 ? 82.538 50.522 41.079 1.00 32.71 ? 391 ASN B ND2 1 ATOM 4798 N N . GLU B 1 202 ? 86.655 50.529 39.922 1.00 23.05 ? 392 GLU B N 1 ATOM 4799 C CA . GLU B 1 202 ? 87.677 51.178 40.730 1.00 26.02 ? 392 GLU B CA 1 ATOM 4800 C C . GLU B 1 202 ? 87.336 52.662 40.699 1.00 26.25 ? 392 GLU B C 1 ATOM 4801 O O . GLU B 1 202 ? 87.310 53.273 39.631 1.00 29.98 ? 392 GLU B O 1 ATOM 4802 C CB . GLU B 1 202 ? 89.059 50.957 40.114 1.00 29.46 ? 392 GLU B CB 1 ATOM 4803 C CG . GLU B 1 202 ? 90.189 51.685 40.823 1.00 37.47 ? 392 GLU B CG 1 ATOM 4804 C CD . GLU B 1 202 ? 91.504 51.580 40.073 1.00 46.42 ? 392 GLU B CD 1 ATOM 4805 O OE1 . GLU B 1 202 ? 92.521 52.111 40.571 1.00 48.55 ? 392 GLU B OE1 1 ATOM 4806 O OE2 . GLU B 1 202 ? 91.520 50.966 38.983 1.00 47.99 ? 392 GLU B OE2 1 ATOM 4807 N N . PRO B 1 203 ? 87.078 53.266 41.869 1.00 25.40 ? 393 PRO B N 1 ATOM 4808 C CA . PRO B 1 203 ? 86.733 54.690 41.925 1.00 22.63 ? 393 PRO B CA 1 ATOM 4809 C C . PRO B 1 203 ? 87.745 55.640 41.291 1.00 22.34 ? 393 PRO B C 1 ATOM 4810 O O . PRO B 1 203 ? 88.952 55.511 41.490 1.00 23.06 ? 393 PRO B O 1 ATOM 4811 C CB . PRO B 1 203 ? 86.553 54.943 43.421 1.00 19.40 ? 393 PRO B CB 1 ATOM 4812 C CG . PRO B 1 203 ? 87.504 53.956 44.045 1.00 20.41 ? 393 PRO B CG 1 ATOM 4813 C CD . PRO B 1 203 ? 87.257 52.714 43.225 1.00 22.58 ? 393 PRO B CD 1 ATOM 4814 N N . LEU B 1 204 ? 87.238 56.591 40.513 1.00 26.32 ? 394 LEU B N 1 ATOM 4815 C CA . LEU B 1 204 ? 88.089 57.585 39.872 1.00 26.94 ? 394 LEU B CA 1 ATOM 4816 C C . LEU B 1 204 ? 88.701 58.452 40.963 1.00 24.45 ? 394 LEU B C 1 ATOM 4817 O O . LEU B 1 204 ? 88.029 58.797 41.940 1.00 20.31 ? 394 LEU B O 1 ATOM 4818 C CB . LEU B 1 204 ? 87.269 58.473 38.930 1.00 27.49 ? 394 LEU B CB 1 ATOM 4819 C CG . LEU B 1 204 ? 86.731 57.864 37.635 1.00 28.19 ? 394 LEU B CG 1 ATOM 4820 C CD1 . LEU B 1 204 ? 85.768 58.844 36.975 1.00 23.01 ? 394 LEU B CD1 1 ATOM 4821 C CD2 . LEU B 1 204 ? 87.887 57.530 36.705 1.00 23.12 ? 394 LEU B CD2 1 ATOM 4822 N N . GLY B 1 205 ? 89.970 58.806 40.791 1.00 25.85 ? 395 GLY B N 1 ATOM 4823 C CA . GLY B 1 205 ? 90.646 59.636 41.772 1.00 24.34 ? 395 GLY B CA 1 ATOM 4824 C C . GLY B 1 205 ? 89.823 60.851 42.152 1.00 25.17 ? 395 GLY B C 1 ATOM 4825 O O . GLY B 1 205 ? 89.809 61.263 43.313 1.00 23.82 ? 395 GLY B O 1 ATOM 4826 N N . THR B 1 206 ? 89.121 61.415 41.174 1.00 22.96 ? 396 THR B N 1 ATOM 4827 C CA . THR B 1 206 ? 88.296 62.592 41.404 1.00 24.50 ? 396 THR B CA 1 ATOM 4828 C C . THR B 1 206 ? 87.001 62.321 42.170 1.00 26.05 ? 396 THR B C 1 ATOM 4829 O O . THR B 1 206 ? 86.382 63.251 42.691 1.00 25.32 ? 396 THR B O 1 ATOM 4830 C CB . THR B 1 206 ? 87.944 63.287 40.074 1.00 25.55 ? 396 THR B CB 1 ATOM 4831 O OG1 . THR B 1 206 ? 87.469 62.314 39.138 1.00 28.78 ? 396 THR B OG1 1 ATOM 4832 C CG2 . THR B 1 206 ? 89.162 63.992 39.503 1.00 25.92 ? 396 THR B CG2 1 ATOM 4833 N N . ASP B 1 207 ? 86.582 61.060 42.238 1.00 28.14 ? 397 ASP B N 1 ATOM 4834 C CA . ASP B 1 207 ? 85.356 60.722 42.958 1.00 28.50 ? 397 ASP B CA 1 ATOM 4835 C C . ASP B 1 207 ? 85.592 60.727 44.464 1.00 27.43 ? 397 ASP B C 1 ATOM 4836 O O . ASP B 1 207 ? 84.691 61.054 45.244 1.00 27.13 ? 397 ASP B O 1 ATOM 4837 C CB . ASP B 1 207 ? 84.830 59.345 42.535 1.00 39.00 ? 397 ASP B CB 1 ATOM 4838 C CG . ASP B 1 207 ? 84.226 59.348 41.140 1.00 44.12 ? 397 ASP B CG 1 ATOM 4839 O OD1 . ASP B 1 207 ? 83.424 60.259 40.841 1.00 41.51 ? 397 ASP B OD1 1 ATOM 4840 O OD2 . ASP B 1 207 ? 84.541 58.430 40.350 1.00 44.15 ? 397 ASP B OD2 1 ATOM 4841 N N . ILE B 1 208 ? 86.808 60.365 44.865 1.00 22.75 ? 398 ILE B N 1 ATOM 4842 C CA . ILE B 1 208 ? 87.181 60.316 46.274 1.00 19.92 ? 398 ILE B CA 1 ATOM 4843 C C . ILE B 1 208 ? 87.221 61.731 46.844 1.00 20.75 ? 398 ILE B C 1 ATOM 4844 O O . ILE B 1 208 ? 88.030 62.555 46.417 1.00 17.12 ? 398 ILE B O 1 ATOM 4845 C CB . ILE B 1 208 ? 88.554 59.648 46.442 1.00 19.94 ? 398 ILE B CB 1 ATOM 4846 C CG1 . ILE B 1 208 ? 88.556 58.303 45.710 1.00 18.65 ? 398 ILE B CG1 1 ATOM 4847 C CG2 . ILE B 1 208 ? 88.857 59.442 47.915 1.00 18.65 ? 398 ILE B CG2 1 ATOM 4848 C CD1 . ILE B 1 208 ? 89.907 57.637 45.640 1.00 20.70 ? 398 ILE B CD1 1 ATOM 4849 N N . ILE B 1 209 ? 86.342 62.002 47.808 1.00 21.23 ? 399 ILE B N 1 ATOM 4850 C CA . ILE B 1 209 ? 86.239 63.325 48.426 1.00 20.25 ? 399 ILE B CA 1 ATOM 4851 C C . ILE B 1 209 ? 87.228 63.567 49.551 1.00 21.71 ? 399 ILE B C 1 ATOM 4852 O O . ILE B 1 209 ? 87.426 64.706 49.978 1.00 24.00 ? 399 ILE B O 1 ATOM 4853 C CB . ILE B 1 209 ? 84.833 63.566 49.006 1.00 19.58 ? 399 ILE B CB 1 ATOM 4854 C CG1 . ILE B 1 209 ? 84.593 62.618 50.185 1.00 20.03 ? 399 ILE B CG1 1 ATOM 4855 C CG2 . ILE B 1 209 ? 83.784 63.354 47.925 1.00 26.36 ? 399 ILE B CG2 1 ATOM 4856 C CD1 . ILE B 1 209 ? 83.339 62.907 50.966 1.00 14.45 ? 399 ILE B CD1 1 ATOM 4857 N N . SER B 1 210 ? 87.839 62.498 50.045 1.00 20.41 ? 400 SER B N 1 ATOM 4858 C CA . SER B 1 210 ? 88.793 62.622 51.135 1.00 16.02 ? 400 SER B CA 1 ATOM 4859 C C . SER B 1 210 ? 90.155 63.034 50.607 1.00 18.46 ? 400 SER B C 1 ATOM 4860 O O . SER B 1 210 ? 90.518 62.700 49.479 1.00 19.40 ? 400 SER B O 1 ATOM 4861 C CB . SER B 1 210 ? 88.925 61.293 51.870 1.00 9.84 ? 400 SER B CB 1 ATOM 4862 O OG . SER B 1 210 ? 89.581 60.338 51.054 1.00 7.00 ? 400 SER B OG 1 ATOM 4863 N N . PRO B 1 211 ? 90.921 63.790 51.409 1.00 18.47 ? 401 PRO B N 1 ATOM 4864 C CA . PRO B 1 211 ? 92.256 64.229 50.995 1.00 17.80 ? 401 PRO B CA 1 ATOM 4865 C C . PRO B 1 211 ? 93.099 62.998 50.666 1.00 14.78 ? 401 PRO B C 1 ATOM 4866 O O . PRO B 1 211 ? 93.113 62.030 51.420 1.00 15.42 ? 401 PRO B O 1 ATOM 4867 C CB . PRO B 1 211 ? 92.766 64.976 52.228 1.00 13.52 ? 401 PRO B CB 1 ATOM 4868 C CG . PRO B 1 211 ? 91.521 65.588 52.768 1.00 13.15 ? 401 PRO B CG 1 ATOM 4869 C CD . PRO B 1 211 ? 90.525 64.445 52.668 1.00 20.94 ? 401 PRO B CD 1 ATOM 4870 N N . PRO B 1 212 ? 93.812 63.022 49.536 1.00 16.39 ? 402 PRO B N 1 ATOM 4871 C CA . PRO B 1 212 ? 94.634 61.867 49.167 1.00 19.61 ? 402 PRO B CA 1 ATOM 4872 C C . PRO B 1 212 ? 95.567 61.382 50.273 1.00 18.47 ? 402 PRO B C 1 ATOM 4873 O O . PRO B 1 212 ? 96.172 62.177 50.991 1.00 13.07 ? 402 PRO B O 1 ATOM 4874 C CB . PRO B 1 212 ? 95.385 62.359 47.930 1.00 16.45 ? 402 PRO B CB 1 ATOM 4875 C CG . PRO B 1 212 ? 95.485 63.833 48.165 1.00 26.42 ? 402 PRO B CG 1 ATOM 4876 C CD . PRO B 1 212 ? 94.106 64.173 48.668 1.00 17.38 ? 402 PRO B CD 1 ATOM 4877 N N . VAL B 1 213 ? 95.657 60.064 50.408 1.00 20.94 ? 403 VAL B N 1 ATOM 4878 C CA . VAL B 1 213 ? 96.516 59.445 51.406 1.00 22.80 ? 403 VAL B CA 1 ATOM 4879 C C . VAL B 1 213 ? 97.464 58.476 50.724 1.00 25.10 ? 403 VAL B C 1 ATOM 4880 O O . VAL B 1 213 ? 97.039 57.463 50.171 1.00 24.64 ? 403 VAL B O 1 ATOM 4881 C CB . VAL B 1 213 ? 95.697 58.678 52.458 1.00 22.54 ? 403 VAL B CB 1 ATOM 4882 C CG1 . VAL B 1 213 ? 96.610 57.780 53.279 1.00 15.22 ? 403 VAL B CG1 1 ATOM 4883 C CG2 . VAL B 1 213 ? 94.984 59.659 53.363 1.00 15.31 ? 403 VAL B CG2 1 ATOM 4884 N N . CYS B 1 214 ? 98.753 58.792 50.761 1.00 26.33 ? 404 CYS B N 1 ATOM 4885 C CA . CYS B 1 214 ? 99.741 57.932 50.139 1.00 24.97 ? 404 CYS B CA 1 ATOM 4886 C C . CYS B 1 214 ? 100.006 56.687 50.978 1.00 24.02 ? 404 CYS B C 1 ATOM 4887 O O . CYS B 1 214 ? 100.464 56.779 52.116 1.00 22.08 ? 404 CYS B O 1 ATOM 4888 C CB . CYS B 1 214 ? 101.054 58.683 49.912 1.00 26.35 ? 404 CYS B CB 1 ATOM 4889 S SG . CYS B 1 214 ? 102.313 57.544 49.267 1.00 31.16 ? 404 CYS B SG 1 ATOM 4890 N N . GLY B 1 215 ? 99.716 55.525 50.401 1.00 26.09 ? 405 GLY B N 1 ATOM 4891 C CA . GLY B 1 215 ? 99.926 54.267 51.095 1.00 23.60 ? 405 GLY B CA 1 ATOM 4892 C C . GLY B 1 215 ? 98.627 53.588 51.490 1.00 24.71 ? 405 GLY B C 1 ATOM 4893 O O . GLY B 1 215 ? 98.640 52.578 52.188 1.00 26.94 ? 405 GLY B O 1 ATOM 4894 N N . ASN B 1 216 ? 97.501 54.134 51.041 1.00 25.03 ? 406 ASN B N 1 ATOM 4895 C CA . ASN B 1 216 ? 96.197 53.570 51.370 1.00 25.27 ? 406 ASN B CA 1 ATOM 4896 C C . ASN B 1 216 ? 95.716 52.622 50.282 1.00 23.29 ? 406 ASN B C 1 ATOM 4897 O O . ASN B 1 216 ? 94.592 52.133 50.328 1.00 22.72 ? 406 ASN B O 1 ATOM 4898 C CB . ASN B 1 216 ? 95.177 54.695 51.573 1.00 30.88 ? 406 ASN B CB 1 ATOM 4899 C CG . ASN B 1 216 ? 94.749 55.338 50.270 1.00 32.38 ? 406 ASN B CG 1 ATOM 4900 O OD1 . ASN B 1 216 ? 95.519 55.398 49.311 1.00 34.70 ? 406 ASN B OD1 1 ATOM 4901 N ND2 . ASN B 1 216 ? 93.518 55.837 50.234 1.00 30.98 ? 406 ASN B ND2 1 ATOM 4902 N N . GLU B 1 217 ? 96.582 52.367 49.306 1.00 23.97 ? 407 GLU B N 1 ATOM 4903 C CA . GLU B 1 217 ? 96.279 51.475 48.191 1.00 22.93 ? 407 GLU B CA 1 ATOM 4904 C C . GLU B 1 217 ? 95.125 51.951 47.322 1.00 22.90 ? 407 GLU B C 1 ATOM 4905 O O . GLU B 1 217 ? 94.342 51.158 46.807 1.00 27.53 ? 407 GLU B O 1 ATOM 4906 C CB . GLU B 1 217 ? 96.020 50.055 48.704 1.00 25.28 ? 407 GLU B CB 1 ATOM 4907 C CG . GLU B 1 217 ? 97.301 49.247 48.845 1.00 28.09 ? 407 GLU B CG 1 ATOM 4908 C CD . GLU B 1 217 ? 97.176 48.084 49.801 1.00 33.45 ? 407 GLU B CD 1 ATOM 4909 O OE1 . GLU B 1 217 ? 96.294 47.224 49.596 1.00 37.95 ? 407 GLU B OE1 1 ATOM 4910 O OE2 . GLU B 1 217 ? 97.973 48.030 50.762 1.00 37.62 ? 407 GLU B OE2 1 ATOM 4911 N N . LEU B 1 218 ? 95.035 53.263 47.165 1.00 23.49 ? 408 LEU B N 1 ATOM 4912 C CA . LEU B 1 218 ? 94.011 53.876 46.336 1.00 20.86 ? 408 LEU B CA 1 ATOM 4913 C C . LEU B 1 218 ? 94.707 54.958 45.522 1.00 20.14 ? 408 LEU B C 1 ATOM 4914 O O . LEU B 1 218 ? 95.276 55.893 46.084 1.00 21.80 ? 408 LEU B O 1 ATOM 4915 C CB . LEU B 1 218 ? 92.912 54.486 47.209 1.00 19.76 ? 408 LEU B CB 1 ATOM 4916 C CG . LEU B 1 218 ? 91.975 53.492 47.903 1.00 20.59 ? 408 LEU B CG 1 ATOM 4917 C CD1 . LEU B 1 218 ? 91.112 54.214 48.932 1.00 12.31 ? 408 LEU B CD1 1 ATOM 4918 C CD2 . LEU B 1 218 ? 91.104 52.800 46.855 1.00 10.31 ? 408 LEU B CD2 1 ATOM 4919 N N . LEU B 1 219 ? 94.686 54.820 44.200 1.00 17.99 ? 409 LEU B N 1 ATOM 4920 C CA . LEU B 1 219 ? 95.335 55.806 43.346 1.00 18.31 ? 409 LEU B CA 1 ATOM 4921 C C . LEU B 1 219 ? 94.505 57.077 43.340 1.00 15.97 ? 409 LEU B C 1 ATOM 4922 O O . LEU B 1 219 ? 93.426 57.132 42.749 1.00 16.59 ? 409 LEU B O 1 ATOM 4923 C CB . LEU B 1 219 ? 95.493 55.273 41.920 1.00 18.36 ? 409 LEU B CB 1 ATOM 4924 C CG . LEU B 1 219 ? 96.367 56.142 41.007 1.00 19.52 ? 409 LEU B CG 1 ATOM 4925 C CD1 . LEU B 1 219 ? 97.762 56.284 41.600 1.00 15.74 ? 409 LEU B CD1 1 ATOM 4926 C CD2 . LEU B 1 219 ? 96.441 55.516 39.632 1.00 19.65 ? 409 LEU B CD2 1 ATOM 4927 N N . GLU B 1 220 ? 95.017 58.100 44.010 1.00 18.07 ? 410 GLU B N 1 ATOM 4928 C CA . GLU B 1 220 ? 94.320 59.371 44.112 1.00 18.33 ? 410 GLU B CA 1 ATOM 4929 C C . GLU B 1 220 ? 95.046 60.464 43.342 1.00 20.26 ? 410 GLU B C 1 ATOM 4930 O O . GLU B 1 220 ? 96.209 60.303 42.953 1.00 15.95 ? 410 GLU B O 1 ATOM 4931 C CB . GLU B 1 220 ? 94.184 59.751 45.586 1.00 20.79 ? 410 GLU B CB 1 ATOM 4932 C CG . GLU B 1 220 ? 93.437 58.698 46.404 1.00 25.73 ? 410 GLU B CG 1 ATOM 4933 C CD . GLU B 1 220 ? 93.667 58.836 47.895 1.00 26.44 ? 410 GLU B CD 1 ATOM 4934 O OE1 . GLU B 1 220 ? 94.820 58.654 48.342 1.00 28.14 ? 410 GLU B OE1 1 ATOM 4935 O OE2 . GLU B 1 220 ? 92.696 59.128 48.622 1.00 30.28 ? 410 GLU B OE2 1 ATOM 4936 N N . VAL B 1 221 ? 94.354 61.578 43.121 1.00 17.17 ? 411 VAL B N 1 ATOM 4937 C CA . VAL B 1 221 ? 94.937 62.692 42.386 1.00 15.24 ? 411 VAL B CA 1 ATOM 4938 C C . VAL B 1 221 ? 96.244 63.168 43.015 1.00 15.05 ? 411 VAL B C 1 ATOM 4939 O O . VAL B 1 221 ? 96.338 63.347 44.232 1.00 15.11 ? 411 VAL B O 1 ATOM 4940 C CB . VAL B 1 221 ? 93.948 63.872 42.297 1.00 14.34 ? 411 VAL B CB 1 ATOM 4941 C CG1 . VAL B 1 221 ? 94.579 65.025 41.533 1.00 11.34 ? 411 VAL B CG1 1 ATOM 4942 C CG2 . VAL B 1 221 ? 92.668 63.418 41.607 1.00 6.65 ? 411 VAL B CG2 1 ATOM 4943 N N . GLY B 1 222 ? 97.252 63.367 42.171 1.00 16.90 ? 412 GLY B N 1 ATOM 4944 C CA . GLY B 1 222 ? 98.548 63.817 42.644 1.00 12.11 ? 412 GLY B CA 1 ATOM 4945 C C . GLY B 1 222 ? 99.483 62.658 42.938 1.00 17.60 ? 412 GLY B C 1 ATOM 4946 O O . GLY B 1 222 ? 100.660 62.864 43.240 1.00 18.92 ? 412 GLY B O 1 ATOM 4947 N N . GLU B 1 223 ? 98.962 61.437 42.852 1.00 16.28 ? 413 GLU B N 1 ATOM 4948 C CA . GLU B 1 223 ? 99.768 60.252 43.122 1.00 17.61 ? 413 GLU B CA 1 ATOM 4949 C C . GLU B 1 223 ? 100.059 59.488 41.841 1.00 17.68 ? 413 GLU B C 1 ATOM 4950 O O . GLU B 1 223 ? 99.146 59.176 41.077 1.00 18.46 ? 413 GLU B O 1 ATOM 4951 C CB . GLU B 1 223 ? 99.044 59.319 44.093 1.00 23.63 ? 413 GLU B CB 1 ATOM 4952 C CG . GLU B 1 223 ? 98.431 59.998 45.299 1.00 28.41 ? 413 GLU B CG 1 ATOM 4953 C CD . GLU B 1 223 ? 97.908 58.997 46.310 1.00 31.82 ? 413 GLU B CD 1 ATOM 4954 O OE1 . GLU B 1 223 ? 97.234 58.030 45.893 1.00 25.60 ? 413 GLU B OE1 1 ATOM 4955 O OE2 . GLU B 1 223 ? 98.169 59.183 47.519 1.00 35.90 ? 413 GLU B OE2 1 ATOM 4956 N N . GLU B 1 224 ? 101.332 59.180 41.613 1.00 15.73 ? 414 GLU B N 1 ATOM 4957 C CA . GLU B 1 224 ? 101.725 58.441 40.424 1.00 15.90 ? 414 GLU B CA 1 ATOM 4958 C C . GLU B 1 224 ? 101.357 56.983 40.616 1.00 16.56 ? 414 GLU B C 1 ATOM 4959 O O . GLU B 1 224 ? 100.999 56.288 39.668 1.00 18.86 ? 414 GLU B O 1 ATOM 4960 C CB . GLU B 1 224 ? 103.228 58.580 40.189 1.00 23.28 ? 414 GLU B CB 1 ATOM 4961 C CG . GLU B 1 224 ? 103.663 60.006 39.895 1.00 29.74 ? 414 GLU B CG 1 ATOM 4962 C CD . GLU B 1 224 ? 105.155 60.136 39.689 1.00 32.05 ? 414 GLU B CD 1 ATOM 4963 O OE1 . GLU B 1 224 ? 105.610 61.246 39.346 1.00 37.97 ? 414 GLU B OE1 1 ATOM 4964 O OE2 . GLU B 1 224 ? 105.876 59.134 39.873 1.00 38.54 ? 414 GLU B OE2 1 ATOM 4965 N N . CYS B 1 225 ? 101.441 56.534 41.862 1.00 19.55 ? 415 CYS B N 1 ATOM 4966 C CA . CYS B 1 225 ? 101.119 55.162 42.224 1.00 21.40 ? 415 CYS B CA 1 ATOM 4967 C C . CYS B 1 225 ? 100.917 55.083 43.728 1.00 21.83 ? 415 CYS B C 1 ATOM 4968 O O . CYS B 1 225 ? 101.338 55.972 44.470 1.00 18.90 ? 415 CYS B O 1 ATOM 4969 C CB . CYS B 1 225 ? 102.254 54.227 41.815 1.00 23.42 ? 415 CYS B CB 1 ATOM 4970 S SG . CYS B 1 225 ? 103.878 54.750 42.449 1.00 34.61 ? 415 CYS B SG 1 ATOM 4971 N N . ASP B 1 226 ? 100.270 54.013 44.172 1.00 22.36 ? 416 ASP B N 1 ATOM 4972 C CA . ASP B 1 226 ? 100.011 53.806 45.589 1.00 22.18 ? 416 ASP B CA 1 ATOM 4973 C C . ASP B 1 226 ? 99.988 52.305 45.834 1.00 26.06 ? 416 ASP B C 1 ATOM 4974 O O . ASP B 1 226 ? 99.024 51.630 45.471 1.00 24.84 ? 416 ASP B O 1 ATOM 4975 C CB . ASP B 1 226 ? 98.662 54.419 45.971 1.00 18.09 ? 416 ASP B CB 1 ATOM 4976 C CG . ASP B 1 226 ? 98.432 54.435 47.468 1.00 19.59 ? 416 ASP B CG 1 ATOM 4977 O OD1 . ASP B 1 226 ? 98.529 53.363 48.099 1.00 16.71 ? 416 ASP B OD1 1 ATOM 4978 O OD2 . ASP B 1 226 ? 98.149 55.522 48.016 1.00 19.58 ? 416 ASP B OD2 1 ATOM 4979 N N . CYS B 1 227 ? 101.057 51.783 46.432 1.00 27.38 ? 417 CYS B N 1 ATOM 4980 C CA . CYS B 1 227 ? 101.151 50.354 46.714 1.00 30.45 ? 417 CYS B CA 1 ATOM 4981 C C . CYS B 1 227 ? 101.144 50.101 48.217 1.00 33.27 ? 417 CYS B C 1 ATOM 4982 O O . CYS B 1 227 ? 101.844 49.220 48.717 1.00 33.56 ? 417 CYS B O 1 ATOM 4983 C CB . CYS B 1 227 ? 102.423 49.765 46.077 1.00 32.26 ? 417 CYS B CB 1 ATOM 4984 S SG . CYS B 1 227 ? 104.025 50.447 46.646 1.00 42.15 ? 417 CYS B SG 1 ATOM 4985 N N . GLY B 1 228 ? 100.341 50.880 48.934 1.00 34.36 ? 418 GLY B N 1 ATOM 4986 C CA . GLY B 1 228 ? 100.263 50.735 50.376 1.00 33.84 ? 418 GLY B CA 1 ATOM 4987 C C . GLY B 1 228 ? 101.538 51.217 51.038 1.00 36.25 ? 418 GLY B C 1 ATOM 4988 O O . GLY B 1 228 ? 102.302 51.982 50.445 1.00 39.36 ? 418 GLY B O 1 ATOM 4989 N N . THR B 1 229 ? 101.772 50.773 52.268 1.00 34.10 ? 419 THR B N 1 ATOM 4990 C CA . THR B 1 229 ? 102.968 51.161 53.005 1.00 32.33 ? 419 THR B CA 1 ATOM 4991 C C . THR B 1 229 ? 104.163 50.399 52.449 1.00 31.15 ? 419 THR B C 1 ATOM 4992 O O . THR B 1 229 ? 103.994 49.366 51.799 1.00 32.23 ? 419 THR B O 1 ATOM 4993 C CB . THR B 1 229 ? 102.818 50.841 54.497 1.00 32.11 ? 419 THR B CB 1 ATOM 4994 O OG1 . THR B 1 229 ? 102.439 49.468 54.649 1.00 35.98 ? 419 THR B OG1 1 ATOM 4995 C CG2 . THR B 1 229 ? 101.754 51.730 55.128 1.00 25.54 ? 419 THR B CG2 1 ATOM 4996 N N . PRO B 1 230 ? 105.388 50.897 52.686 1.00 31.85 ? 420 PRO B N 1 ATOM 4997 C CA . PRO B 1 230 ? 106.564 50.192 52.166 1.00 32.61 ? 420 PRO B CA 1 ATOM 4998 C C . PRO B 1 230 ? 106.663 48.741 52.626 1.00 33.13 ? 420 PRO B C 1 ATOM 4999 O O . PRO B 1 230 ? 107.345 47.932 52.001 1.00 37.88 ? 420 PRO B O 1 ATOM 5000 C CB . PRO B 1 230 ? 107.736 51.057 52.643 1.00 25.84 ? 420 PRO B CB 1 ATOM 5001 C CG . PRO B 1 230 ? 107.192 51.764 53.848 1.00 31.60 ? 420 PRO B CG 1 ATOM 5002 C CD . PRO B 1 230 ? 105.785 52.105 53.430 1.00 32.56 ? 420 PRO B CD 1 ATOM 5003 N N . GLU B 1 231 ? 105.966 48.412 53.708 1.00 33.16 ? 421 GLU B N 1 ATOM 5004 C CA . GLU B 1 231 ? 105.976 47.054 54.237 1.00 35.21 ? 421 GLU B CA 1 ATOM 5005 C C . GLU B 1 231 ? 105.047 46.140 53.449 1.00 34.43 ? 421 GLU B C 1 ATOM 5006 O O . GLU B 1 231 ? 105.386 44.991 53.171 1.00 32.96 ? 421 GLU B O 1 ATOM 5007 C CB . GLU B 1 231 ? 105.564 47.048 55.713 1.00 41.53 ? 421 GLU B CB 1 ATOM 5008 C CG . GLU B 1 231 ? 106.613 47.620 56.658 1.00 52.37 ? 421 GLU B CG 1 ATOM 5009 C CD . GLU B 1 231 ? 106.845 49.106 56.460 1.00 56.39 ? 421 GLU B CD 1 ATOM 5010 O OE1 . GLU B 1 231 ? 107.828 49.635 57.023 1.00 59.77 ? 421 GLU B OE1 1 ATOM 5011 O OE2 . GLU B 1 231 ? 106.041 49.748 55.751 1.00 59.72 ? 421 GLU B OE2 1 ATOM 5012 N N . ASN B 1 232 ? 103.876 46.650 53.086 1.00 33.36 ? 422 ASN B N 1 ATOM 5013 C CA . ASN B 1 232 ? 102.909 45.857 52.336 1.00 33.17 ? 422 ASN B CA 1 ATOM 5014 C C . ASN B 1 232 ? 103.081 45.957 50.826 1.00 32.45 ? 422 ASN B C 1 ATOM 5015 O O . ASN B 1 232 ? 102.567 45.117 50.089 1.00 28.09 ? 422 ASN B O 1 ATOM 5016 C CB . ASN B 1 232 ? 101.482 46.274 52.705 1.00 36.74 ? 422 ASN B CB 1 ATOM 5017 C CG . ASN B 1 232 ? 101.111 45.895 54.122 1.00 39.48 ? 422 ASN B CG 1 ATOM 5018 O OD1 . ASN B 1 232 ? 101.117 44.720 54.480 1.00 44.60 ? 422 ASN B OD1 1 ATOM 5019 N ND2 . ASN B 1 232 ? 100.784 46.891 54.937 1.00 41.95 ? 422 ASN B ND2 1 ATOM 5020 N N . CYS B 1 233 ? 103.802 46.979 50.369 1.00 36.72 ? 423 CYS B N 1 ATOM 5021 C CA . CYS B 1 233 ? 104.007 47.190 48.937 1.00 40.29 ? 423 CYS B CA 1 ATOM 5022 C C . CYS B 1 233 ? 104.527 45.957 48.211 1.00 42.81 ? 423 CYS B C 1 ATOM 5023 O O . CYS B 1 233 ? 105.563 45.396 48.568 1.00 43.21 ? 423 CYS B O 1 ATOM 5024 C CB . CYS B 1 233 ? 104.960 48.368 48.697 1.00 40.99 ? 423 CYS B CB 1 ATOM 5025 S SG . CYS B 1 233 ? 105.207 48.812 46.940 1.00 42.24 ? 423 CYS B SG 1 ATOM 5026 N N . GLN B 1 234 ? 103.787 45.539 47.190 1.00 45.56 ? 424 GLN B N 1 ATOM 5027 C CA . GLN B 1 234 ? 104.157 44.382 46.387 1.00 48.32 ? 424 GLN B CA 1 ATOM 5028 C C . GLN B 1 234 ? 104.428 44.849 44.963 1.00 48.63 ? 424 GLN B C 1 ATOM 5029 O O . GLN B 1 234 ? 104.635 44.037 44.062 1.00 52.17 ? 424 GLN B O 1 ATOM 5030 C CB . GLN B 1 234 ? 103.025 43.351 46.379 1.00 53.38 ? 424 GLN B CB 1 ATOM 5031 C CG . GLN B 1 234 ? 102.631 42.824 47.752 1.00 59.30 ? 424 GLN B CG 1 ATOM 5032 C CD . GLN B 1 234 ? 103.752 42.061 48.434 1.00 64.45 ? 424 GLN B CD 1 ATOM 5033 O OE1 . GLN B 1 234 ? 104.262 41.075 47.901 1.00 64.60 ? 424 GLN B OE1 1 ATOM 5034 N NE2 . GLN B 1 234 ? 104.139 42.513 49.623 1.00 68.04 ? 424 GLN B NE2 1 ATOM 5035 N N . ASN B 1 235 ? 104.414 46.166 44.766 1.00 46.85 ? 425 ASN B N 1 ATOM 5036 C CA . ASN B 1 235 ? 104.662 46.753 43.453 1.00 42.73 ? 425 ASN B CA 1 ATOM 5037 C C . ASN B 1 235 ? 106.114 47.208 43.356 1.00 42.13 ? 425 ASN B C 1 ATOM 5038 O O . ASN B 1 235 ? 106.601 47.954 44.207 1.00 42.06 ? 425 ASN B O 1 ATOM 5039 C CB . ASN B 1 235 ? 103.730 47.943 43.220 1.00 36.49 ? 425 ASN B CB 1 ATOM 5040 C CG . ASN B 1 235 ? 103.845 48.507 41.818 1.00 36.22 ? 425 ASN B CG 1 ATOM 5041 O OD1 . ASN B 1 235 ? 103.145 49.454 41.459 1.00 39.41 ? 425 ASN B OD1 1 ATOM 5042 N ND2 . ASN B 1 235 ? 104.732 47.928 41.015 1.00 36.74 ? 425 ASN B ND2 1 ATOM 5043 N N . GLU B 1 236 ? 106.799 46.762 42.310 1.00 41.67 ? 426 GLU B N 1 ATOM 5044 C CA . GLU B 1 236 ? 108.200 47.110 42.126 1.00 43.36 ? 426 GLU B CA 1 ATOM 5045 C C . GLU B 1 236 ? 108.430 48.349 41.262 1.00 41.39 ? 426 GLU B C 1 ATOM 5046 O O . GLU B 1 236 ? 109.570 48.679 40.928 1.00 37.31 ? 426 GLU B O 1 ATOM 5047 C CB . GLU B 1 236 ? 108.950 45.907 41.550 1.00 43.76 ? 426 GLU B CB 1 ATOM 5048 C CG . GLU B 1 236 ? 108.817 44.664 42.420 1.00 54.06 ? 426 GLU B CG 1 ATOM 5049 C CD . GLU B 1 236 ? 109.815 43.575 42.070 1.00 58.23 ? 426 GLU B CD 1 ATOM 5050 O OE1 . GLU B 1 236 ? 111.034 43.840 42.154 1.00 56.11 ? 426 GLU B OE1 1 ATOM 5051 O OE2 . GLU B 1 236 ? 109.378 42.456 41.719 1.00 57.61 ? 426 GLU B OE2 1 ATOM 5052 N N . CYS B 1 237 ? 107.350 49.044 40.917 1.00 35.31 ? 427 CYS B N 1 ATOM 5053 C CA . CYS B 1 237 ? 107.461 50.244 40.098 1.00 33.37 ? 427 CYS B CA 1 ATOM 5054 C C . CYS B 1 237 ? 107.225 51.484 40.938 1.00 32.86 ? 427 CYS B C 1 ATOM 5055 O O . CYS B 1 237 ? 107.503 52.604 40.510 1.00 34.91 ? 427 CYS B O 1 ATOM 5056 C CB . CYS B 1 237 ? 106.423 50.223 38.985 1.00 33.05 ? 427 CYS B CB 1 ATOM 5057 S SG . CYS B 1 237 ? 106.228 48.625 38.149 1.00 40.67 ? 427 CYS B SG 1 ATOM 5058 N N . CYS B 1 238 ? 106.716 51.277 42.143 1.00 34.54 ? 428 CYS B N 1 ATOM 5059 C CA . CYS B 1 238 ? 106.391 52.381 43.026 1.00 33.90 ? 428 CYS B CA 1 ATOM 5060 C C . CYS B 1 238 ? 107.350 52.546 44.195 1.00 34.68 ? 428 CYS B C 1 ATOM 5061 O O . CYS B 1 238 ? 108.088 51.627 44.550 1.00 35.63 ? 428 CYS B O 1 ATOM 5062 C CB . CYS B 1 238 ? 104.969 52.177 43.561 1.00 32.03 ? 428 CYS B CB 1 ATOM 5063 S SG . CYS B 1 238 ? 104.135 53.679 44.155 1.00 30.67 ? 428 CYS B SG 1 ATOM 5064 N N . ASP B 1 239 ? 107.336 53.741 44.771 1.00 33.81 ? 429 ASP B N 1 ATOM 5065 C CA . ASP B 1 239 ? 108.136 54.056 45.944 1.00 33.35 ? 429 ASP B CA 1 ATOM 5066 C C . ASP B 1 239 ? 107.086 54.229 47.030 1.00 33.69 ? 429 ASP B C 1 ATOM 5067 O O . ASP B 1 239 ? 106.650 55.347 47.312 1.00 32.45 ? 429 ASP B O 1 ATOM 5068 C CB . ASP B 1 239 ? 108.895 55.367 45.765 1.00 36.84 ? 429 ASP B CB 1 ATOM 5069 C CG . ASP B 1 239 ? 109.643 55.777 47.018 1.00 37.29 ? 429 ASP B CG 1 ATOM 5070 O OD1 . ASP B 1 239 ? 110.155 56.916 47.066 1.00 40.92 ? 429 ASP B OD1 1 ATOM 5071 O OD2 . ASP B 1 239 ? 109.722 54.955 47.957 1.00 38.12 ? 429 ASP B OD2 1 ATOM 5072 N N . ALA B 1 240 ? 106.669 53.110 47.614 1.00 30.17 ? 430 ALA B N 1 ATOM 5073 C CA . ALA B 1 240 ? 105.644 53.090 48.650 1.00 26.75 ? 430 ALA B CA 1 ATOM 5074 C C . ALA B 1 240 ? 105.632 54.303 49.579 1.00 26.98 ? 430 ALA B C 1 ATOM 5075 O O . ALA B 1 240 ? 104.575 54.716 50.054 1.00 32.62 ? 430 ALA B O 1 ATOM 5076 C CB . ALA B 1 240 ? 105.778 51.818 49.462 1.00 21.56 ? 430 ALA B CB 1 ATOM 5077 N N . ALA B 1 241 ? 106.801 54.877 49.831 1.00 23.84 ? 431 ALA B N 1 ATOM 5078 C CA . ALA B 1 241 ? 106.910 56.027 50.720 1.00 26.02 ? 431 ALA B CA 1 ATOM 5079 C C . ALA B 1 241 ? 106.418 57.360 50.149 1.00 26.11 ? 431 ALA B C 1 ATOM 5080 O O . ALA B 1 241 ? 105.742 58.117 50.842 1.00 29.34 ? 431 ALA B O 1 ATOM 5081 C CB . ALA B 1 241 ? 108.356 56.171 51.191 1.00 28.69 ? 431 ALA B CB 1 ATOM 5082 N N . THR B 1 242 ? 106.746 57.645 48.892 1.00 28.59 ? 432 THR B N 1 ATOM 5083 C CA . THR B 1 242 ? 106.359 58.913 48.270 1.00 28.37 ? 432 THR B CA 1 ATOM 5084 C C . THR B 1 242 ? 105.233 58.862 47.233 1.00 24.92 ? 432 THR B C 1 ATOM 5085 O O . THR B 1 242 ? 104.740 59.903 46.801 1.00 28.45 ? 432 THR B O 1 ATOM 5086 C CB . THR B 1 242 ? 107.579 59.574 47.599 1.00 28.15 ? 432 THR B CB 1 ATOM 5087 O OG1 . THR B 1 242 ? 108.100 58.701 46.589 1.00 28.83 ? 432 THR B OG1 1 ATOM 5088 C CG2 . THR B 1 242 ? 108.662 59.852 48.625 1.00 26.32 ? 432 THR B CG2 1 ATOM 5089 N N . CYS B 1 243 ? 104.829 57.664 46.835 1.00 21.29 ? 433 CYS B N 1 ATOM 5090 C CA . CYS B 1 243 ? 103.778 57.508 45.834 1.00 24.40 ? 433 CYS B CA 1 ATOM 5091 C C . CYS B 1 243 ? 104.180 58.043 44.465 1.00 27.42 ? 433 CYS B C 1 ATOM 5092 O O . CYS B 1 243 ? 103.352 58.552 43.709 1.00 31.76 ? 433 CYS B O 1 ATOM 5093 C CB . CYS B 1 243 ? 102.480 58.168 46.310 1.00 22.24 ? 433 CYS B CB 1 ATOM 5094 S SG . CYS B 1 243 ? 101.579 57.062 47.435 1.00 23.87 ? 433 CYS B SG 1 ATOM 5095 N N . LYS B 1 244 ? 105.466 57.915 44.154 1.00 28.87 ? 434 LYS B N 1 ATOM 5096 C CA . LYS B 1 244 ? 106.008 58.351 42.874 1.00 27.30 ? 434 LYS B CA 1 ATOM 5097 C C . LYS B 1 244 ? 106.648 57.143 42.205 1.00 26.94 ? 434 LYS B C 1 ATOM 5098 O O . LYS B 1 244 ? 107.383 56.393 42.852 1.00 26.83 ? 434 LYS B O 1 ATOM 5099 C CB . LYS B 1 244 ? 107.075 59.436 43.076 1.00 24.10 ? 434 LYS B CB 1 ATOM 5100 C CG . LYS B 1 244 ? 106.556 60.763 43.599 1.00 27.21 ? 434 LYS B CG 1 ATOM 5101 C CD . LYS B 1 244 ? 105.586 61.394 42.614 1.00 40.07 ? 434 LYS B CD 1 ATOM 5102 C CE . LYS B 1 244 ? 105.001 62.697 43.146 1.00 43.76 ? 434 LYS B CE 1 ATOM 5103 N NZ . LYS B 1 244 ? 103.987 63.267 42.212 1.00 42.78 ? 434 LYS B NZ 1 ATOM 5104 N N . LEU B 1 245 ? 106.360 56.937 40.923 1.00 24.92 ? 435 LEU B N 1 ATOM 5105 C CA . LEU B 1 245 ? 106.958 55.822 40.196 1.00 24.52 ? 435 LEU B CA 1 ATOM 5106 C C . LEU B 1 245 ? 108.470 55.993 40.288 1.00 25.05 ? 435 LEU B C 1 ATOM 5107 O O . LEU B 1 245 ? 108.979 57.107 40.152 1.00 24.07 ? 435 LEU B O 1 ATOM 5108 C CB . LEU B 1 245 ? 106.534 55.847 38.725 1.00 17.45 ? 435 LEU B CB 1 ATOM 5109 C CG . LEU B 1 245 ? 105.077 55.515 38.391 1.00 22.47 ? 435 LEU B CG 1 ATOM 5110 C CD1 . LEU B 1 245 ? 104.845 55.697 36.893 1.00 15.17 ? 435 LEU B CD1 1 ATOM 5111 C CD2 . LEU B 1 245 ? 104.762 54.083 38.812 1.00 9.88 ? 435 LEU B CD2 1 ATOM 5112 N N . LYS B 1 246 ? 109.195 54.910 40.535 1.00 23.28 ? 436 LYS B N 1 ATOM 5113 C CA . LYS B 1 246 ? 110.638 55.041 40.624 1.00 29.67 ? 436 LYS B CA 1 ATOM 5114 C C . LYS B 1 246 ? 111.220 55.313 39.243 1.00 29.96 ? 436 LYS B C 1 ATOM 5115 O O . LYS B 1 246 ? 110.621 54.968 38.225 1.00 26.96 ? 436 LYS B O 1 ATOM 5116 C CB . LYS B 1 246 ? 111.268 53.797 41.261 1.00 29.40 ? 436 LYS B CB 1 ATOM 5117 C CG . LYS B 1 246 ? 110.707 52.472 40.805 1.00 33.86 ? 436 LYS B CG 1 ATOM 5118 C CD . LYS B 1 246 ? 110.330 51.618 42.011 1.00 36.71 ? 436 LYS B CD 1 ATOM 5119 C CE . LYS B 1 246 ? 111.492 51.465 42.984 1.00 35.16 ? 436 LYS B CE 1 ATOM 5120 N NZ . LYS B 1 246 ? 111.118 50.665 44.186 1.00 35.77 ? 436 LYS B NZ 1 ATOM 5121 N N . SER B 1 247 ? 112.380 55.960 39.220 1.00 30.69 ? 437 SER B N 1 ATOM 5122 C CA . SER B 1 247 ? 113.041 56.313 37.972 1.00 31.79 ? 437 SER B CA 1 ATOM 5123 C C . SER B 1 247 ? 113.168 55.144 37.008 1.00 29.30 ? 437 SER B C 1 ATOM 5124 O O . SER B 1 247 ? 113.575 54.048 37.391 1.00 27.33 ? 437 SER B O 1 ATOM 5125 C CB . SER B 1 247 ? 114.426 56.894 38.266 1.00 36.62 ? 437 SER B CB 1 ATOM 5126 O OG . SER B 1 247 ? 114.319 58.049 39.083 1.00 42.83 ? 437 SER B OG 1 ATOM 5127 N N . GLY B 1 248 ? 112.806 55.387 35.752 1.00 26.81 ? 438 GLY B N 1 ATOM 5128 C CA . GLY B 1 248 ? 112.900 54.349 34.744 1.00 23.89 ? 438 GLY B CA 1 ATOM 5129 C C . GLY B 1 248 ? 111.573 53.718 34.386 1.00 20.07 ? 438 GLY B C 1 ATOM 5130 O O . GLY B 1 248 ? 111.368 53.293 33.250 1.00 17.23 ? 438 GLY B O 1 ATOM 5131 N N . SER B 1 249 ? 110.667 53.653 35.352 1.00 23.22 ? 439 SER B N 1 ATOM 5132 C CA . SER B 1 249 ? 109.361 53.055 35.110 1.00 32.98 ? 439 SER B CA 1 ATOM 5133 C C . SER B 1 249 ? 108.404 54.021 34.416 1.00 31.91 ? 439 SER B C 1 ATOM 5134 O O . SER B 1 249 ? 108.461 55.234 34.630 1.00 34.28 ? 439 SER B O 1 ATOM 5135 C CB . SER B 1 249 ? 108.751 52.563 36.429 1.00 31.50 ? 439 SER B CB 1 ATOM 5136 O OG . SER B 1 249 ? 108.656 53.612 37.373 1.00 39.77 ? 439 SER B OG 1 ATOM 5137 N N . GLN B 1 250 ? 107.533 53.471 33.576 1.00 30.81 ? 440 GLN B N 1 ATOM 5138 C CA . GLN B 1 250 ? 106.558 54.267 32.844 1.00 28.82 ? 440 GLN B CA 1 ATOM 5139 C C . GLN B 1 250 ? 105.186 54.232 33.506 1.00 29.05 ? 440 GLN B C 1 ATOM 5140 O O . GLN B 1 250 ? 104.393 55.158 33.354 1.00 26.89 ? 440 GLN B O 1 ATOM 5141 C CB . GLN B 1 250 ? 106.443 53.763 31.404 1.00 25.30 ? 440 GLN B CB 1 ATOM 5142 C CG . GLN B 1 250 ? 107.620 54.136 30.523 1.00 24.41 ? 440 GLN B CG 1 ATOM 5143 C CD . GLN B 1 250 ? 107.481 53.619 29.101 1.00 27.51 ? 440 GLN B CD 1 ATOM 5144 O OE1 . GLN B 1 250 ? 108.077 54.167 28.174 1.00 23.83 ? 440 GLN B OE1 1 ATOM 5145 N NE2 . GLN B 1 250 ? 106.703 52.554 28.924 1.00 24.67 ? 440 GLN B NE2 1 ATOM 5146 N N . CYS B 1 251 ? 104.916 53.164 34.247 1.00 29.89 ? 441 CYS B N 1 ATOM 5147 C CA . CYS B 1 251 ? 103.633 53.006 34.920 1.00 31.15 ? 441 CYS B CA 1 ATOM 5148 C C . CYS B 1 251 ? 103.765 52.082 36.125 1.00 33.01 ? 441 CYS B C 1 ATOM 5149 O O . CYS B 1 251 ? 104.811 51.467 36.337 1.00 34.54 ? 441 CYS B O 1 ATOM 5150 C CB . CYS B 1 251 ? 102.612 52.427 33.945 1.00 29.91 ? 441 CYS B CB 1 ATOM 5151 S SG . CYS B 1 251 ? 103.233 50.933 33.112 1.00 27.56 ? 441 CYS B SG 1 ATOM 5152 N N . GLY B 1 252 ? 102.696 51.987 36.908 1.00 32.79 ? 442 GLY B N 1 ATOM 5153 C CA . GLY B 1 252 ? 102.713 51.137 38.084 1.00 31.63 ? 442 GLY B CA 1 ATOM 5154 C C . GLY B 1 252 ? 101.362 50.495 38.310 1.00 30.93 ? 442 GLY B C 1 ATOM 5155 O O . GLY B 1 252 ? 101.130 49.849 39.332 1.00 29.16 ? 442 GLY B O 1 ATOM 5156 N N . HIS B 1 253 ? 100.470 50.679 37.342 1.00 32.19 ? 443 HIS B N 1 ATOM 5157 C CA . HIS B 1 253 ? 99.123 50.127 37.401 1.00 33.00 ? 443 HIS B CA 1 ATOM 5158 C C . HIS B 1 253 ? 98.514 50.145 36.002 1.00 32.35 ? 443 HIS B C 1 ATOM 5159 O O . HIS B 1 253 ? 99.042 50.792 35.097 1.00 29.30 ? 443 HIS B O 1 ATOM 5160 C CB . HIS B 1 253 ? 98.253 50.965 38.335 1.00 36.41 ? 443 HIS B CB 1 ATOM 5161 C CG . HIS B 1 253 ? 97.945 52.327 37.799 1.00 41.93 ? 443 HIS B CG 1 ATOM 5162 N ND1 . HIS B 1 253 ? 98.923 53.265 37.548 1.00 47.33 ? 443 HIS B ND1 1 ATOM 5163 C CD2 . HIS B 1 253 ? 96.773 52.898 37.435 1.00 45.16 ? 443 HIS B CD2 1 ATOM 5164 C CE1 . HIS B 1 253 ? 98.366 54.355 37.051 1.00 48.24 ? 443 HIS B CE1 1 ATOM 5165 N NE2 . HIS B 1 253 ? 97.063 54.158 36.972 1.00 46.91 ? 443 HIS B NE2 1 ATOM 5166 N N . GLY B 1 254 ? 97.400 49.437 35.832 1.00 33.01 ? 444 GLY B N 1 ATOM 5167 C CA . GLY B 1 254 ? 96.734 49.403 34.542 1.00 30.18 ? 444 GLY B CA 1 ATOM 5168 C C . GLY B 1 254 ? 96.879 48.093 33.796 1.00 31.02 ? 444 GLY B C 1 ATOM 5169 O O . GLY B 1 254 ? 97.943 47.480 33.798 1.00 34.33 ? 444 GLY B O 1 ATOM 5170 N N . ASP B 1 255 ? 95.803 47.663 33.146 1.00 34.10 ? 445 ASP B N 1 ATOM 5171 C CA . ASP B 1 255 ? 95.821 46.418 32.388 1.00 34.21 ? 445 ASP B CA 1 ATOM 5172 C C . ASP B 1 255 ? 96.808 46.499 31.230 1.00 33.02 ? 445 ASP B C 1 ATOM 5173 O O . ASP B 1 255 ? 97.010 45.521 30.511 1.00 35.15 ? 445 ASP B O 1 ATOM 5174 C CB . ASP B 1 255 ? 94.421 46.100 31.852 1.00 35.15 ? 445 ASP B CB 1 ATOM 5175 C CG . ASP B 1 255 ? 93.418 45.828 32.959 1.00 31.99 ? 445 ASP B CG 1 ATOM 5176 O OD1 . ASP B 1 255 ? 93.640 44.884 33.750 1.00 33.34 ? 445 ASP B OD1 1 ATOM 5177 O OD2 . ASP B 1 255 ? 92.408 46.558 33.034 1.00 18.81 ? 445 ASP B OD2 1 ATOM 5178 N N . CYS B 1 256 ? 97.411 47.669 31.044 1.00 30.85 ? 446 CYS B N 1 ATOM 5179 C CA . CYS B 1 256 ? 98.388 47.852 29.978 1.00 33.43 ? 446 CYS B CA 1 ATOM 5180 C C . CYS B 1 256 ? 99.762 48.210 30.524 1.00 35.06 ? 446 CYS B C 1 ATOM 5181 O O . CYS B 1 256 ? 100.589 48.797 29.824 1.00 35.87 ? 446 CYS B O 1 ATOM 5182 C CB . CYS B 1 256 ? 97.926 48.924 28.993 1.00 27.82 ? 446 CYS B CB 1 ATOM 5183 S SG . CYS B 1 256 ? 96.607 48.352 27.882 1.00 34.48 ? 446 CYS B SG 1 ATOM 5184 N N . CYS B 1 257 ? 99.995 47.857 31.785 1.00 35.19 ? 447 CYS B N 1 ATOM 5185 C CA . CYS B 1 257 ? 101.277 48.110 32.422 1.00 31.26 ? 447 CYS B CA 1 ATOM 5186 C C . CYS B 1 257 ? 101.950 46.781 32.730 1.00 31.86 ? 447 CYS B C 1 ATOM 5187 O O . CYS B 1 257 ? 101.576 46.090 33.677 1.00 29.42 ? 447 CYS B O 1 ATOM 5188 C CB . CYS B 1 257 ? 101.099 48.895 33.716 1.00 29.43 ? 447 CYS B CB 1 ATOM 5189 S SG . CYS B 1 257 ? 102.708 49.428 34.372 1.00 29.21 ? 447 CYS B SG 1 ATOM 5190 N N . GLU B 1 258 ? 102.943 46.422 31.925 1.00 35.29 ? 448 GLU B N 1 ATOM 5191 C CA . GLU B 1 258 ? 103.645 45.163 32.121 1.00 39.74 ? 448 GLU B CA 1 ATOM 5192 C C . GLU B 1 258 ? 105.107 45.381 32.511 1.00 37.60 ? 448 GLU B C 1 ATOM 5193 O O . GLU B 1 258 ? 105.915 45.850 31.708 1.00 32.46 ? 448 GLU B O 1 ATOM 5194 C CB . GLU B 1 258 ? 103.551 44.319 30.849 1.00 42.66 ? 448 GLU B CB 1 ATOM 5195 C CG . GLU B 1 258 ? 103.639 42.824 31.094 1.00 56.52 ? 448 GLU B CG 1 ATOM 5196 C CD . GLU B 1 258 ? 103.357 42.014 29.843 1.00 65.76 ? 448 GLU B CD 1 ATOM 5197 O OE1 . GLU B 1 258 ? 102.296 42.234 29.216 1.00 67.07 ? 448 GLU B OE1 1 ATOM 5198 O OE2 . GLU B 1 258 ? 104.193 41.155 29.489 1.00 72.02 ? 448 GLU B OE2 1 ATOM 5199 N N . GLN B 1 259 ? 105.428 45.041 33.756 1.00 37.69 ? 449 GLN B N 1 ATOM 5200 C CA . GLN B 1 259 ? 106.781 45.183 34.283 1.00 39.05 ? 449 GLN B CA 1 ATOM 5201 C C . GLN B 1 259 ? 107.227 46.637 34.354 1.00 37.83 ? 449 GLN B C 1 ATOM 5202 O O . GLN B 1 259 ? 108.362 46.963 34.007 1.00 38.52 ? 449 GLN B O 1 ATOM 5203 C CB . GLN B 1 259 ? 107.765 44.382 33.428 1.00 43.04 ? 449 GLN B CB 1 ATOM 5204 C CG . GLN B 1 259 ? 107.487 42.891 33.417 1.00 48.65 ? 449 GLN B CG 1 ATOM 5205 C CD . GLN B 1 259 ? 107.427 42.316 34.816 1.00 51.61 ? 449 GLN B CD 1 ATOM 5206 O OE1 . GLN B 1 259 ? 108.375 42.441 35.591 1.00 55.24 ? 449 GLN B OE1 1 ATOM 5207 N NE2 . GLN B 1 259 ? 106.309 41.682 35.149 1.00 57.27 ? 449 GLN B NE2 1 ATOM 5208 N N . CYS B 1 260 ? 106.328 47.504 34.808 1.00 34.60 ? 450 CYS B N 1 ATOM 5209 C CA . CYS B 1 260 ? 106.614 48.930 34.936 1.00 31.10 ? 450 CYS B CA 1 ATOM 5210 C C . CYS B 1 260 ? 106.700 49.639 33.590 1.00 29.07 ? 450 CYS B C 1 ATOM 5211 O O . CYS B 1 260 ? 107.015 50.827 33.532 1.00 27.05 ? 450 CYS B O 1 ATOM 5212 C CB . CYS B 1 260 ? 107.924 49.150 35.690 1.00 30.37 ? 450 CYS B CB 1 ATOM 5213 S SG . CYS B 1 260 ? 108.040 48.299 37.292 1.00 35.95 ? 450 CYS B SG 1 ATOM 5214 N N . LYS B 1 261 ? 106.423 48.914 32.511 1.00 24.14 ? 451 LYS B N 1 ATOM 5215 C CA . LYS B 1 261 ? 106.479 49.501 31.177 1.00 23.90 ? 451 LYS B CA 1 ATOM 5216 C C . LYS B 1 261 ? 105.154 49.403 30.427 1.00 20.97 ? 451 LYS B C 1 ATOM 5217 O O . LYS B 1 261 ? 104.336 48.535 30.715 1.00 27.55 ? 451 LYS B O 1 ATOM 5218 C CB . LYS B 1 261 ? 107.591 48.831 30.359 1.00 23.42 ? 451 LYS B CB 1 ATOM 5219 C CG . LYS B 1 261 ? 108.991 49.382 30.630 1.00 23.92 ? 451 LYS B CG 1 ATOM 5220 C CD . LYS B 1 261 ? 109.469 49.077 32.042 1.00 26.35 ? 451 LYS B CD 1 ATOM 5221 C CE . LYS B 1 261 ? 110.527 50.079 32.517 1.00 24.33 ? 451 LYS B CE 1 ATOM 5222 N NZ . LYS B 1 261 ? 111.725 50.151 31.640 1.00 20.34 ? 451 LYS B NZ 1 ATOM 5223 N N . PHE B 1 262 ? 104.940 50.308 29.476 1.00 20.28 ? 452 PHE B N 1 ATOM 5224 C CA . PHE B 1 262 ? 103.721 50.296 28.669 1.00 20.30 ? 452 PHE B CA 1 ATOM 5225 C C . PHE B 1 262 ? 103.708 49.003 27.866 1.00 20.02 ? 452 PHE B C 1 ATOM 5226 O O . PHE B 1 262 ? 104.737 48.592 27.331 1.00 22.48 ? 452 PHE B O 1 ATOM 5227 C CB . PHE B 1 262 ? 103.698 51.488 27.704 1.00 18.01 ? 452 PHE B CB 1 ATOM 5228 C CG . PHE B 1 262 ? 103.459 52.812 28.373 1.00 23.04 ? 452 PHE B CG 1 ATOM 5229 C CD1 . PHE B 1 262 ? 103.951 53.987 27.808 1.00 26.07 ? 452 PHE B CD1 1 ATOM 5230 C CD2 . PHE B 1 262 ? 102.734 52.892 29.565 1.00 25.96 ? 452 PHE B CD2 1 ATOM 5231 C CE1 . PHE B 1 262 ? 103.730 55.225 28.417 1.00 24.94 ? 452 PHE B CE1 1 ATOM 5232 C CE2 . PHE B 1 262 ? 102.505 54.120 30.183 1.00 23.99 ? 452 PHE B CE2 1 ATOM 5233 C CZ . PHE B 1 262 ? 103.005 55.291 29.609 1.00 27.36 ? 452 PHE B CZ 1 ATOM 5234 N N . SER B 1 263 ? 102.550 48.357 27.782 1.00 20.76 ? 453 SER B N 1 ATOM 5235 C CA . SER B 1 263 ? 102.451 47.112 27.034 1.00 21.95 ? 453 SER B CA 1 ATOM 5236 C C . SER B 1 263 ? 102.687 47.346 25.549 1.00 22.53 ? 453 SER B C 1 ATOM 5237 O O . SER B 1 263 ? 102.343 48.396 25.009 1.00 21.70 ? 453 SER B O 1 ATOM 5238 C CB . SER B 1 263 ? 101.082 46.470 27.240 1.00 18.66 ? 453 SER B CB 1 ATOM 5239 O OG . SER B 1 263 ? 100.914 46.072 28.588 1.00 31.67 ? 453 SER B OG 1 ATOM 5240 N N . LYS B 1 264 ? 103.287 46.357 24.899 1.00 24.66 ? 454 LYS B N 1 ATOM 5241 C CA . LYS B 1 264 ? 103.575 46.435 23.476 1.00 27.71 ? 454 LYS B CA 1 ATOM 5242 C C . LYS B 1 264 ? 102.301 46.861 22.751 1.00 30.18 ? 454 LYS B C 1 ATOM 5243 O O . LYS B 1 264 ? 101.224 46.325 23.015 1.00 26.29 ? 454 LYS B O 1 ATOM 5244 C CB . LYS B 1 264 ? 104.021 45.067 22.947 1.00 31.43 ? 454 LYS B CB 1 ATOM 5245 C CG . LYS B 1 264 ? 105.212 44.423 23.669 1.00 36.07 ? 454 LYS B CG 1 ATOM 5246 C CD . LYS B 1 264 ? 104.970 44.208 25.170 1.00 35.50 ? 454 LYS B CD 1 ATOM 5247 C CE . LYS B 1 264 ? 103.696 43.426 25.461 1.00 26.21 ? 454 LYS B CE 1 ATOM 5248 N NZ . LYS B 1 264 ? 103.723 42.058 24.881 1.00 29.12 ? 454 LYS B NZ 1 ATOM 5249 N N . SER B 1 265 ? 102.420 47.830 21.850 1.00 29.67 ? 455 SER B N 1 ATOM 5250 C CA . SER B 1 265 ? 101.266 48.289 21.089 1.00 26.63 ? 455 SER B CA 1 ATOM 5251 C C . SER B 1 265 ? 100.548 47.080 20.499 1.00 27.90 ? 455 SER B C 1 ATOM 5252 O O . SER B 1 265 ? 101.180 46.080 20.146 1.00 23.92 ? 455 SER B O 1 ATOM 5253 C CB . SER B 1 265 ? 101.708 49.218 19.959 1.00 27.66 ? 455 SER B CB 1 ATOM 5254 O OG . SER B 1 265 ? 100.624 49.528 19.100 1.00 28.25 ? 455 SER B OG 1 ATOM 5255 N N . GLY B 1 266 ? 99.225 47.170 20.405 1.00 27.57 ? 456 GLY B N 1 ATOM 5256 C CA . GLY B 1 266 ? 98.456 46.074 19.852 1.00 24.93 ? 456 GLY B CA 1 ATOM 5257 C C . GLY B 1 266 ? 98.319 44.861 20.755 1.00 26.84 ? 456 GLY B C 1 ATOM 5258 O O . GLY B 1 266 ? 97.907 43.799 20.294 1.00 28.42 ? 456 GLY B O 1 ATOM 5259 N N . THR B 1 267 ? 98.664 44.992 22.031 1.00 27.97 ? 457 THR B N 1 ATOM 5260 C CA . THR B 1 267 ? 98.522 43.859 22.939 1.00 33.82 ? 457 THR B CA 1 ATOM 5261 C C . THR B 1 267 ? 97.162 43.910 23.626 1.00 34.97 ? 457 THR B C 1 ATOM 5262 O O . THR B 1 267 ? 96.877 44.805 24.426 1.00 35.42 ? 457 THR B O 1 ATOM 5263 C CB . THR B 1 267 ? 99.636 43.816 24.019 1.00 35.87 ? 457 THR B CB 1 ATOM 5264 O OG1 . THR B 1 267 ? 99.706 45.073 24.698 1.00 46.23 ? 457 THR B OG1 1 ATOM 5265 C CG2 . THR B 1 267 ? 100.979 43.501 23.386 1.00 37.16 ? 457 THR B CG2 1 ATOM 5266 N N . GLU B 1 268 ? 96.323 42.940 23.283 1.00 31.66 ? 458 GLU B N 1 ATOM 5267 C CA . GLU B 1 268 ? 94.982 42.822 23.833 1.00 29.51 ? 458 GLU B CA 1 ATOM 5268 C C . GLU B 1 268 ? 94.962 43.041 25.343 1.00 27.06 ? 458 GLU B C 1 ATOM 5269 O O . GLU B 1 268 ? 95.710 42.399 26.077 1.00 19.65 ? 458 GLU B O 1 ATOM 5270 C CB . GLU B 1 268 ? 94.431 41.439 23.497 1.00 27.45 ? 458 GLU B CB 1 ATOM 5271 C CG . GLU B 1 268 ? 93.080 41.129 24.091 1.00 34.22 ? 458 GLU B CG 1 ATOM 5272 C CD . GLU B 1 268 ? 92.650 39.710 23.794 1.00 36.86 ? 458 GLU B CD 1 ATOM 5273 O OE1 . GLU B 1 268 ? 92.486 39.377 22.598 1.00 35.06 ? 458 GLU B OE1 1 ATOM 5274 O OE2 . GLU B 1 268 ? 92.484 38.930 24.756 1.00 37.64 ? 458 GLU B OE2 1 ATOM 5275 N N . CYS B 1 269 ? 94.104 43.950 25.802 1.00 30.24 ? 459 CYS B N 1 ATOM 5276 C CA . CYS B 1 269 ? 93.997 44.239 27.228 1.00 27.25 ? 459 CYS B CA 1 ATOM 5277 C C . CYS B 1 269 ? 92.603 43.996 27.798 1.00 28.37 ? 459 CYS B C 1 ATOM 5278 O O . CYS B 1 269 ? 92.361 44.223 28.983 1.00 32.74 ? 459 CYS B O 1 ATOM 5279 C CB . CYS B 1 269 ? 94.435 45.672 27.517 1.00 22.01 ? 459 CYS B CB 1 ATOM 5280 S SG . CYS B 1 269 ? 93.568 46.984 26.603 1.00 31.94 ? 459 CYS B SG 1 ATOM 5281 N N . ARG B 1 270 ? 91.683 43.556 26.947 1.00 27.11 ? 460 ARG B N 1 ATOM 5282 C CA . ARG B 1 270 ? 90.329 43.230 27.378 1.00 23.62 ? 460 ARG B CA 1 ATOM 5283 C C . ARG B 1 270 ? 89.761 42.201 26.412 1.00 25.79 ? 460 ARG B C 1 ATOM 5284 O O . ARG B 1 270 ? 89.367 42.529 25.288 1.00 19.35 ? 460 ARG B O 1 ATOM 5285 C CB . ARG B 1 270 ? 89.423 44.460 27.419 1.00 23.78 ? 460 ARG B CB 1 ATOM 5286 C CG . ARG B 1 270 ? 88.037 44.121 27.969 1.00 25.20 ? 460 ARG B CG 1 ATOM 5287 C CD . ARG B 1 270 ? 87.091 45.307 28.013 1.00 24.95 ? 460 ARG B CD 1 ATOM 5288 N NE . ARG B 1 270 ? 87.483 46.311 28.998 1.00 23.96 ? 460 ARG B NE 1 ATOM 5289 C CZ . ARG B 1 270 ? 87.991 47.500 28.689 1.00 25.37 ? 460 ARG B CZ 1 ATOM 5290 N NH1 . ARG B 1 270 ? 88.172 47.835 27.420 1.00 24.66 ? 460 ARG B NH1 1 ATOM 5291 N NH2 . ARG B 1 270 ? 88.313 48.357 29.649 1.00 20.54 ? 460 ARG B NH2 1 ATOM 5292 N N . ALA B 1 271 ? 89.738 40.952 26.867 1.00 26.29 ? 461 ALA B N 1 ATOM 5293 C CA . ALA B 1 271 ? 89.254 39.827 26.078 1.00 25.63 ? 461 ALA B CA 1 ATOM 5294 C C . ALA B 1 271 ? 87.851 40.013 25.509 1.00 28.30 ? 461 ALA B C 1 ATOM 5295 O O . ALA B 1 271 ? 86.992 40.659 26.114 1.00 27.24 ? 461 ALA B O 1 ATOM 5296 C CB . ALA B 1 271 ? 89.308 38.558 26.912 1.00 24.66 ? 461 ALA B CB 1 ATOM 5297 N N . SER B 1 272 ? 87.636 39.423 24.337 1.00 27.21 ? 462 SER B N 1 ATOM 5298 C CA . SER B 1 272 ? 86.359 39.494 23.644 1.00 25.25 ? 462 SER B CA 1 ATOM 5299 C C . SER B 1 272 ? 85.396 38.407 24.115 1.00 27.83 ? 462 SER B C 1 ATOM 5300 O O . SER B 1 272 ? 85.737 37.221 24.127 1.00 25.95 ? 462 SER B O 1 ATOM 5301 C CB . SER B 1 272 ? 86.586 39.363 22.137 1.00 23.37 ? 462 SER B CB 1 ATOM 5302 O OG . SER B 1 272 ? 85.362 39.200 21.443 1.00 27.16 ? 462 SER B OG 1 ATOM 5303 N N . MET B 1 273 ? 84.191 38.823 24.500 1.00 31.79 ? 463 MET B N 1 ATOM 5304 C CA . MET B 1 273 ? 83.163 37.898 24.969 1.00 32.34 ? 463 MET B CA 1 ATOM 5305 C C . MET B 1 273 ? 82.654 37.076 23.788 1.00 30.80 ? 463 MET B C 1 ATOM 5306 O O . MET B 1 273 ? 82.760 35.848 23.776 1.00 29.28 ? 463 MET B O 1 ATOM 5307 C CB . MET B 1 273 ? 81.999 38.677 25.595 1.00 36.57 ? 463 MET B CB 1 ATOM 5308 C CG . MET B 1 273 ? 82.411 39.695 26.657 1.00 38.52 ? 463 MET B CG 1 ATOM 5309 S SD . MET B 1 273 ? 80.997 40.615 27.344 1.00 48.14 ? 463 MET B SD 1 ATOM 5310 C CE . MET B 1 273 ? 80.953 39.988 29.022 1.00 44.04 ? 463 MET B CE 1 ATOM 5311 N N . SER B 1 274 ? 82.103 37.775 22.800 1.00 27.72 ? 464 SER B N 1 ATOM 5312 C CA . SER B 1 274 ? 81.568 37.161 21.588 1.00 24.31 ? 464 SER B CA 1 ATOM 5313 C C . SER B 1 274 ? 81.829 38.102 20.414 1.00 27.38 ? 464 SER B C 1 ATOM 5314 O O . SER B 1 274 ? 82.469 39.141 20.579 1.00 29.01 ? 464 SER B O 1 ATOM 5315 C CB . SER B 1 274 ? 80.059 36.928 21.727 1.00 26.76 ? 464 SER B CB 1 ATOM 5316 O OG . SER B 1 274 ? 79.346 38.152 21.837 1.00 7.69 ? 464 SER B OG 1 ATOM 5317 N N . GLU B 1 275 ? 81.328 37.748 19.234 1.00 28.17 ? 465 GLU B N 1 ATOM 5318 C CA . GLU B 1 275 ? 81.520 38.586 18.053 1.00 28.78 ? 465 GLU B CA 1 ATOM 5319 C C . GLU B 1 275 ? 80.944 39.984 18.254 1.00 27.29 ? 465 GLU B C 1 ATOM 5320 O O . GLU B 1 275 ? 81.343 40.929 17.576 1.00 30.83 ? 465 GLU B O 1 ATOM 5321 C CB . GLU B 1 275 ? 80.881 37.933 16.826 1.00 26.91 ? 465 GLU B CB 1 ATOM 5322 C CG . GLU B 1 275 ? 79.405 37.619 16.975 1.00 32.03 ? 465 GLU B CG 1 ATOM 5323 C CD . GLU B 1 275 ? 78.871 36.798 15.814 1.00 33.70 ? 465 GLU B CD 1 ATOM 5324 O OE1 . GLU B 1 275 ? 78.703 37.357 14.707 1.00 30.84 ? 465 GLU B OE1 1 ATOM 5325 O OE2 . GLU B 1 275 ? 78.630 35.587 16.008 1.00 33.54 ? 465 GLU B OE2 1 ATOM 5326 N N . CYS B 1 276 ? 80.017 40.111 19.198 1.00 28.14 ? 466 CYS B N 1 ATOM 5327 C CA . CYS B 1 276 ? 79.382 41.394 19.496 1.00 25.21 ? 466 CYS B CA 1 ATOM 5328 C C . CYS B 1 276 ? 80.248 42.276 20.383 1.00 20.75 ? 466 CYS B C 1 ATOM 5329 O O . CYS B 1 276 ? 79.877 43.410 20.694 1.00 17.66 ? 466 CYS B O 1 ATOM 5330 C CB . CYS B 1 276 ? 78.048 41.177 20.203 1.00 20.80 ? 466 CYS B CB 1 ATOM 5331 S SG . CYS B 1 276 ? 76.798 40.269 19.252 1.00 27.53 ? 466 CYS B SG 1 ATOM 5332 N N . ASP B 1 277 ? 81.392 41.751 20.802 1.00 15.98 ? 467 ASP B N 1 ATOM 5333 C CA . ASP B 1 277 ? 82.290 42.502 21.666 1.00 16.19 ? 467 ASP B CA 1 ATOM 5334 C C . ASP B 1 277 ? 83.708 42.547 21.100 1.00 18.22 ? 467 ASP B C 1 ATOM 5335 O O . ASP B 1 277 ? 84.514 41.649 21.346 1.00 23.45 ? 467 ASP B O 1 ATOM 5336 C CB . ASP B 1 277 ? 82.311 41.867 23.056 1.00 16.67 ? 467 ASP B CB 1 ATOM 5337 C CG . ASP B 1 277 ? 83.103 42.677 24.056 1.00 19.39 ? 467 ASP B CG 1 ATOM 5338 O OD1 . ASP B 1 277 ? 83.337 42.172 25.176 1.00 22.28 ? 467 ASP B OD1 1 ATOM 5339 O OD2 . ASP B 1 277 ? 83.487 43.819 23.724 1.00 24.55 ? 467 ASP B OD2 1 ATOM 5340 N N . PRO B 1 278 ? 84.029 43.590 20.323 1.00 13.15 ? 468 PRO B N 1 ATOM 5341 C CA . PRO B 1 278 ? 85.378 43.671 19.766 1.00 11.38 ? 468 PRO B CA 1 ATOM 5342 C C . PRO B 1 278 ? 86.353 43.938 20.904 1.00 14.93 ? 468 PRO B C 1 ATOM 5343 O O . PRO B 1 278 ? 86.103 44.788 21.761 1.00 15.83 ? 468 PRO B O 1 ATOM 5344 C CB . PRO B 1 278 ? 85.274 44.842 18.801 1.00 12.29 ? 468 PRO B CB 1 ATOM 5345 C CG . PRO B 1 278 ? 84.326 45.758 19.524 1.00 16.12 ? 468 PRO B CG 1 ATOM 5346 C CD . PRO B 1 278 ? 83.250 44.796 19.996 1.00 15.15 ? 468 PRO B CD 1 ATOM 5347 N N . ALA B 1 279 ? 87.459 43.208 20.920 1.00 14.80 ? 469 ALA B N 1 ATOM 5348 C CA . ALA B 1 279 ? 88.448 43.374 21.975 1.00 18.96 ? 469 ALA B CA 1 ATOM 5349 C C . ALA B 1 279 ? 89.222 44.683 21.846 1.00 18.36 ? 469 ALA B C 1 ATOM 5350 O O . ALA B 1 279 ? 89.356 45.233 20.755 1.00 21.65 ? 469 ALA B O 1 ATOM 5351 C CB . ALA B 1 279 ? 89.413 42.192 21.967 1.00 13.40 ? 469 ALA B CB 1 ATOM 5352 N N . GLU B 1 280 ? 89.715 45.184 22.974 1.00 21.14 ? 470 GLU B N 1 ATOM 5353 C CA . GLU B 1 280 ? 90.507 46.407 22.992 1.00 21.88 ? 470 GLU B CA 1 ATOM 5354 C C . GLU B 1 280 ? 91.973 46.004 23.113 1.00 24.08 ? 470 GLU B C 1 ATOM 5355 O O . GLU B 1 280 ? 92.292 44.943 23.653 1.00 21.54 ? 470 GLU B O 1 ATOM 5356 C CB . GLU B 1 280 ? 90.114 47.302 24.171 1.00 18.72 ? 470 GLU B CB 1 ATOM 5357 C CG . GLU B 1 280 ? 88.737 47.940 24.040 1.00 21.50 ? 470 GLU B CG 1 ATOM 5358 C CD . GLU B 1 280 ? 87.608 46.942 24.187 1.00 21.96 ? 470 GLU B CD 1 ATOM 5359 O OE1 . GLU B 1 280 ? 86.462 47.290 23.845 1.00 22.83 ? 470 GLU B OE1 1 ATOM 5360 O OE2 . GLU B 1 280 ? 87.860 45.812 24.652 1.00 29.42 ? 470 GLU B OE2 1 ATOM 5361 N N . HIS B 1 281 ? 92.863 46.851 22.612 1.00 26.32 ? 471 HIS B N 1 ATOM 5362 C CA . HIS B 1 281 ? 94.288 46.555 22.656 1.00 28.97 ? 471 HIS B CA 1 ATOM 5363 C C . HIS B 1 281 ? 95.060 47.770 23.150 1.00 28.96 ? 471 HIS B C 1 ATOM 5364 O O . HIS B 1 281 ? 94.659 48.909 22.903 1.00 26.70 ? 471 HIS B O 1 ATOM 5365 C CB . HIS B 1 281 ? 94.762 46.165 21.257 1.00 30.98 ? 471 HIS B CB 1 ATOM 5366 C CG . HIS B 1 281 ? 93.866 45.178 20.577 1.00 35.66 ? 471 HIS B CG 1 ATOM 5367 N ND1 . HIS B 1 281 ? 93.787 43.857 20.960 1.00 39.41 ? 471 HIS B ND1 1 ATOM 5368 C CD2 . HIS B 1 281 ? 92.980 45.331 19.565 1.00 38.52 ? 471 HIS B CD2 1 ATOM 5369 C CE1 . HIS B 1 281 ? 92.891 43.236 20.212 1.00 37.85 ? 471 HIS B CE1 1 ATOM 5370 N NE2 . HIS B 1 281 ? 92.387 44.109 19.358 1.00 40.74 ? 471 HIS B NE2 1 ATOM 5371 N N . CYS B 1 282 ? 96.164 47.530 23.851 1.00 26.01 ? 472 CYS B N 1 ATOM 5372 C CA . CYS B 1 282 ? 96.962 48.632 24.361 1.00 25.75 ? 472 CYS B CA 1 ATOM 5373 C C . CYS B 1 282 ? 97.522 49.447 23.203 1.00 25.16 ? 472 CYS B C 1 ATOM 5374 O O . CYS B 1 282 ? 97.901 48.895 22.168 1.00 24.36 ? 472 CYS B O 1 ATOM 5375 C CB . CYS B 1 282 ? 98.100 48.111 25.234 1.00 22.35 ? 472 CYS B CB 1 ATOM 5376 S SG . CYS B 1 282 ? 97.541 47.067 26.615 1.00 36.46 ? 472 CYS B SG 1 ATOM 5377 N N . THR B 1 283 ? 97.558 50.763 23.381 1.00 22.34 ? 473 THR B N 1 ATOM 5378 C CA . THR B 1 283 ? 98.070 51.665 22.358 1.00 25.35 ? 473 THR B CA 1 ATOM 5379 C C . THR B 1 283 ? 99.583 51.546 22.219 1.00 25.39 ? 473 THR B C 1 ATOM 5380 O O . THR B 1 283 ? 100.147 51.887 21.185 1.00 24.40 ? 473 THR B O 1 ATOM 5381 C CB . THR B 1 283 ? 97.731 53.127 22.695 1.00 29.54 ? 473 THR B CB 1 ATOM 5382 O OG1 . THR B 1 283 ? 98.232 53.445 24.001 1.00 35.47 ? 473 THR B OG1 1 ATOM 5383 C CG2 . THR B 1 283 ? 96.228 53.345 22.666 1.00 33.57 ? 473 THR B CG2 1 ATOM 5384 N N . GLY B 1 284 ? 100.235 51.058 23.268 1.00 30.23 ? 474 GLY B N 1 ATOM 5385 C CA . GLY B 1 284 ? 101.678 50.915 23.237 1.00 32.29 ? 474 GLY B CA 1 ATOM 5386 C C . GLY B 1 284 ? 102.335 52.146 23.824 1.00 35.14 ? 474 GLY B C 1 ATOM 5387 O O . GLY B 1 284 ? 103.547 52.179 24.041 1.00 35.38 ? 474 GLY B O 1 ATOM 5388 N N . GLN B 1 285 ? 101.521 53.164 24.084 1.00 36.47 ? 475 GLN B N 1 ATOM 5389 C CA . GLN B 1 285 ? 102.002 54.415 24.650 1.00 40.80 ? 475 GLN B CA 1 ATOM 5390 C C . GLN B 1 285 ? 101.149 54.835 25.847 1.00 39.56 ? 475 GLN B C 1 ATOM 5391 O O . GLN B 1 285 ? 101.170 55.995 26.259 1.00 37.72 ? 475 GLN B O 1 ATOM 5392 C CB . GLN B 1 285 ? 101.967 55.514 23.588 1.00 43.43 ? 475 GLN B CB 1 ATOM 5393 C CG . GLN B 1 285 ? 100.579 55.768 23.031 1.00 52.30 ? 475 GLN B CG 1 ATOM 5394 C CD . GLN B 1 285 ? 100.513 57.009 22.165 1.00 57.33 ? 475 GLN B CD 1 ATOM 5395 O OE1 . GLN B 1 285 ? 99.455 57.352 21.632 1.00 60.79 ? 475 GLN B OE1 1 ATOM 5396 N NE2 . GLN B 1 285 ? 101.643 57.692 22.021 1.00 58.55 ? 475 GLN B NE2 1 ATOM 5397 N N . SER B 1 286 ? 100.398 53.889 26.401 1.00 38.61 ? 476 SER B N 1 ATOM 5398 C CA . SER B 1 286 ? 99.541 54.166 27.548 1.00 34.88 ? 476 SER B CA 1 ATOM 5399 C C . SER B 1 286 ? 99.455 52.950 28.463 1.00 32.80 ? 476 SER B C 1 ATOM 5400 O O . SER B 1 286 ? 99.539 51.813 28.006 1.00 32.59 ? 476 SER B O 1 ATOM 5401 C CB . SER B 1 286 ? 98.138 54.551 27.071 1.00 35.94 ? 476 SER B CB 1 ATOM 5402 O OG . SER B 1 286 ? 97.266 54.777 28.167 1.00 41.46 ? 476 SER B OG 1 ATOM 5403 N N . SER B 1 287 ? 99.283 53.191 29.757 1.00 31.33 ? 477 SER B N 1 ATOM 5404 C CA . SER B 1 287 ? 99.189 52.098 30.714 1.00 32.69 ? 477 SER B CA 1 ATOM 5405 C C . SER B 1 287 ? 97.737 51.697 30.946 1.00 33.84 ? 477 SER B C 1 ATOM 5406 O O . SER B 1 287 ? 97.455 50.710 31.630 1.00 33.24 ? 477 SER B O 1 ATOM 5407 C CB . SER B 1 287 ? 99.822 52.505 32.044 1.00 30.12 ? 477 SER B CB 1 ATOM 5408 O OG . SER B 1 287 ? 99.132 53.600 32.617 1.00 32.14 ? 477 SER B OG 1 ATOM 5409 N N . GLU B 1 288 ? 96.816 52.459 30.369 1.00 32.87 ? 478 GLU B N 1 ATOM 5410 C CA . GLU B 1 288 ? 95.400 52.174 30.539 1.00 34.94 ? 478 GLU B CA 1 ATOM 5411 C C . GLU B 1 288 ? 94.735 51.587 29.303 1.00 30.90 ? 478 GLU B C 1 ATOM 5412 O O . GLU B 1 288 ? 94.937 52.056 28.183 1.00 28.43 ? 478 GLU B O 1 ATOM 5413 C CB . GLU B 1 288 ? 94.661 53.443 30.970 1.00 43.75 ? 478 GLU B CB 1 ATOM 5414 C CG . GLU B 1 288 ? 95.141 53.991 32.300 1.00 49.38 ? 478 GLU B CG 1 ATOM 5415 C CD . GLU B 1 288 ? 94.946 53.004 33.433 1.00 52.70 ? 478 GLU B CD 1 ATOM 5416 O OE1 . GLU B 1 288 ? 95.555 53.203 34.505 1.00 56.16 ? 478 GLU B OE1 1 ATOM 5417 O OE2 . GLU B 1 288 ? 94.179 52.032 33.254 1.00 51.78 ? 478 GLU B OE2 1 ATOM 5418 N N . CYS B 1 289 ? 93.938 50.550 29.529 1.00 28.29 ? 479 CYS B N 1 ATOM 5419 C CA . CYS B 1 289 ? 93.212 49.872 28.467 1.00 25.41 ? 479 CYS B CA 1 ATOM 5420 C C . CYS B 1 289 ? 92.095 50.798 27.991 1.00 23.51 ? 479 CYS B C 1 ATOM 5421 O O . CYS B 1 289 ? 91.315 51.308 28.798 1.00 21.03 ? 479 CYS B O 1 ATOM 5422 C CB . CYS B 1 289 ? 92.622 48.572 29.012 1.00 26.13 ? 479 CYS B CB 1 ATOM 5423 S SG . CYS B 1 289 ? 91.962 47.406 27.778 1.00 35.61 ? 479 CYS B SG 1 ATOM 5424 N N . PRO B 1 290 ? 92.009 51.036 26.673 1.00 20.86 ? 480 PRO B N 1 ATOM 5425 C CA . PRO B 1 290 ? 90.964 51.917 26.141 1.00 18.25 ? 480 PRO B CA 1 ATOM 5426 C C . PRO B 1 290 ? 89.549 51.445 26.473 1.00 17.70 ? 480 PRO B C 1 ATOM 5427 O O . PRO B 1 290 ? 89.313 50.251 26.660 1.00 16.24 ? 480 PRO B O 1 ATOM 5428 C CB . PRO B 1 290 ? 91.258 51.933 24.642 1.00 14.88 ? 480 PRO B CB 1 ATOM 5429 C CG . PRO B 1 290 ? 91.906 50.605 24.407 1.00 22.36 ? 480 PRO B CG 1 ATOM 5430 C CD . PRO B 1 290 ? 92.828 50.477 25.585 1.00 16.19 ? 480 PRO B CD 1 ATOM 5431 N N . ALA B 1 291 ? 88.620 52.396 26.552 1.00 17.29 ? 481 ALA B N 1 ATOM 5432 C CA . ALA B 1 291 ? 87.220 52.116 26.873 1.00 14.42 ? 481 ALA B CA 1 ATOM 5433 C C . ALA B 1 291 ? 86.690 50.867 26.179 1.00 15.40 ? 481 ALA B C 1 ATOM 5434 O O . ALA B 1 291 ? 87.145 50.508 25.091 1.00 14.49 ? 481 ALA B O 1 ATOM 5435 C CB . ALA B 1 291 ? 86.359 53.310 26.506 1.00 12.42 ? 481 ALA B CB 1 ATOM 5436 N N . ASP B 1 292 ? 85.723 50.209 26.815 1.00 14.04 ? 482 ASP B N 1 ATOM 5437 C CA . ASP B 1 292 ? 85.142 48.996 26.250 1.00 16.17 ? 482 ASP B CA 1 ATOM 5438 C C . ASP B 1 292 ? 84.093 49.305 25.187 1.00 16.39 ? 482 ASP B C 1 ATOM 5439 O O . ASP B 1 292 ? 83.101 49.986 25.444 1.00 20.00 ? 482 ASP B O 1 ATOM 5440 C CB . ASP B 1 292 ? 84.526 48.131 27.353 1.00 15.16 ? 482 ASP B CB 1 ATOM 5441 C CG . ASP B 1 292 ? 84.176 46.731 26.870 1.00 22.18 ? 482 ASP B CG 1 ATOM 5442 O OD1 . ASP B 1 292 ? 84.647 46.340 25.780 1.00 18.46 ? 482 ASP B OD1 1 ATOM 5443 O OD2 . ASP B 1 292 ? 83.440 46.016 27.585 1.00 24.00 ? 482 ASP B OD2 1 ATOM 5444 N N . VAL B 1 293 ? 84.333 48.796 23.986 1.00 15.67 ? 483 VAL B N 1 ATOM 5445 C CA . VAL B 1 293 ? 83.432 48.994 22.864 1.00 12.36 ? 483 VAL B CA 1 ATOM 5446 C C . VAL B 1 293 ? 82.659 47.711 22.565 1.00 16.24 ? 483 VAL B C 1 ATOM 5447 O O . VAL B 1 293 ? 83.214 46.609 22.581 1.00 12.25 ? 483 VAL B O 1 ATOM 5448 C CB . VAL B 1 293 ? 84.216 49.410 21.578 1.00 14.39 ? 483 VAL B CB 1 ATOM 5449 C CG1 . VAL B 1 293 ? 83.273 49.488 20.385 1.00 1.00 ? 483 VAL B CG1 1 ATOM 5450 C CG2 . VAL B 1 293 ? 84.905 50.751 21.789 1.00 8.01 ? 483 VAL B CG2 1 ATOM 5451 N N . PHE B 1 294 ? 81.367 47.872 22.310 1.00 17.24 ? 484 PHE B N 1 ATOM 5452 C CA . PHE B 1 294 ? 80.492 46.764 21.959 1.00 15.25 ? 484 PHE B CA 1 ATOM 5453 C C . PHE B 1 294 ? 79.988 47.143 20.583 1.00 15.40 ? 484 PHE B C 1 ATOM 5454 O O . PHE B 1 294 ? 79.998 48.319 20.230 1.00 15.76 ? 484 PHE B O 1 ATOM 5455 C CB . PHE B 1 294 ? 79.276 46.697 22.888 1.00 16.69 ? 484 PHE B CB 1 ATOM 5456 C CG . PHE B 1 294 ? 79.573 46.208 24.273 1.00 19.07 ? 484 PHE B CG 1 ATOM 5457 C CD1 . PHE B 1 294 ? 78.621 46.354 25.279 1.00 15.42 ? 484 PHE B CD1 1 ATOM 5458 C CD2 . PHE B 1 294 ? 80.779 45.587 24.577 1.00 25.43 ? 484 PHE B CD2 1 ATOM 5459 C CE1 . PHE B 1 294 ? 78.863 45.892 26.563 1.00 22.68 ? 484 PHE B CE1 1 ATOM 5460 C CE2 . PHE B 1 294 ? 81.033 45.119 25.865 1.00 27.33 ? 484 PHE B CE2 1 ATOM 5461 C CZ . PHE B 1 294 ? 80.072 45.272 26.859 1.00 25.02 ? 484 PHE B CZ 1 ATOM 5462 N N . HIS B 1 295 ? 79.562 46.167 19.795 1.00 14.15 ? 485 HIS B N 1 ATOM 5463 C CA . HIS B 1 295 ? 78.996 46.503 18.502 1.00 15.76 ? 485 HIS B CA 1 ATOM 5464 C C . HIS B 1 295 ? 77.577 46.958 18.827 1.00 14.66 ? 485 HIS B C 1 ATOM 5465 O O . HIS B 1 295 ? 77.143 46.856 19.972 1.00 14.43 ? 485 HIS B O 1 ATOM 5466 C CB . HIS B 1 295 ? 79.013 45.293 17.579 1.00 19.31 ? 485 HIS B CB 1 ATOM 5467 C CG . HIS B 1 295 ? 80.363 45.023 16.992 1.00 28.77 ? 485 HIS B CG 1 ATOM 5468 N ND1 . HIS B 1 295 ? 80.685 43.838 16.366 1.00 34.83 ? 485 HIS B ND1 1 ATOM 5469 C CD2 . HIS B 1 295 ? 81.475 45.794 16.931 1.00 27.17 ? 485 HIS B CD2 1 ATOM 5470 C CE1 . HIS B 1 295 ? 81.937 43.891 15.946 1.00 33.69 ? 485 HIS B CE1 1 ATOM 5471 N NE2 . HIS B 1 295 ? 82.438 45.068 16.276 1.00 28.53 ? 485 HIS B NE2 1 ATOM 5472 N N . LYS B 1 296 ? 76.855 47.472 17.844 1.00 14.45 ? 486 LYS B N 1 ATOM 5473 C CA . LYS B 1 296 ? 75.507 47.964 18.103 1.00 13.50 ? 486 LYS B CA 1 ATOM 5474 C C . LYS B 1 296 ? 74.492 46.883 18.451 1.00 10.63 ? 486 LYS B C 1 ATOM 5475 O O . LYS B 1 296 ? 74.535 45.775 17.916 1.00 12.32 ? 486 LYS B O 1 ATOM 5476 C CB . LYS B 1 296 ? 75.006 48.760 16.899 1.00 12.60 ? 486 LYS B CB 1 ATOM 5477 C CG . LYS B 1 296 ? 75.875 49.942 16.532 1.00 13.22 ? 486 LYS B CG 1 ATOM 5478 C CD . LYS B 1 296 ? 75.358 50.607 15.268 1.00 18.91 ? 486 LYS B CD 1 ATOM 5479 C CE . LYS B 1 296 ? 76.180 51.827 14.911 1.00 19.30 ? 486 LYS B CE 1 ATOM 5480 N NZ . LYS B 1 296 ? 75.608 52.532 13.738 1.00 24.89 ? 486 LYS B NZ 1 ATOM 5481 N N . ASN B 1 297 ? 73.581 47.214 19.360 1.00 11.41 ? 487 ASN B N 1 ATOM 5482 C CA . ASN B 1 297 ? 72.530 46.282 19.753 1.00 14.68 ? 487 ASN B CA 1 ATOM 5483 C C . ASN B 1 297 ? 71.606 46.096 18.554 1.00 13.88 ? 487 ASN B C 1 ATOM 5484 O O . ASN B 1 297 ? 71.254 47.066 17.879 1.00 14.63 ? 487 ASN B O 1 ATOM 5485 C CB . ASN B 1 297 ? 71.745 46.830 20.947 1.00 10.69 ? 487 ASN B CB 1 ATOM 5486 C CG . ASN B 1 297 ? 72.514 46.710 22.251 1.00 20.89 ? 487 ASN B CG 1 ATOM 5487 O OD1 . ASN B 1 297 ? 72.101 47.246 23.282 1.00 23.36 ? 487 ASN B OD1 1 ATOM 5488 N ND2 . ASN B 1 297 ? 73.637 45.993 22.214 1.00 16.33 ? 487 ASN B ND2 1 ATOM 5489 N N . GLY B 1 298 ? 71.225 44.850 18.287 1.00 9.37 ? 488 GLY B N 1 ATOM 5490 C CA . GLY B 1 298 ? 70.366 44.573 17.152 1.00 9.88 ? 488 GLY B CA 1 ATOM 5491 C C . GLY B 1 298 ? 71.193 44.027 16.009 1.00 12.87 ? 488 GLY B C 1 ATOM 5492 O O . GLY B 1 298 ? 70.670 43.415 15.078 1.00 16.46 ? 488 GLY B O 1 ATOM 5493 N N . GLN B 1 299 ? 72.499 44.266 16.082 1.00 18.46 ? 489 GLN B N 1 ATOM 5494 C CA . GLN B 1 299 ? 73.443 43.794 15.076 1.00 18.39 ? 489 GLN B CA 1 ATOM 5495 C C . GLN B 1 299 ? 73.340 42.269 14.979 1.00 17.98 ? 489 GLN B C 1 ATOM 5496 O O . GLN B 1 299 ? 73.788 41.554 15.873 1.00 20.35 ? 489 GLN B O 1 ATOM 5497 C CB . GLN B 1 299 ? 74.860 44.208 15.486 1.00 18.13 ? 489 GLN B CB 1 ATOM 5498 C CG . GLN B 1 299 ? 75.984 43.398 14.856 1.00 17.18 ? 489 GLN B CG 1 ATOM 5499 C CD . GLN B 1 299 ? 76.274 43.803 13.435 1.00 19.29 ? 489 GLN B CD 1 ATOM 5500 O OE1 . GLN B 1 299 ? 76.706 44.928 13.176 1.00 20.11 ? 489 GLN B OE1 1 ATOM 5501 N NE2 . GLN B 1 299 ? 76.041 42.888 12.499 1.00 20.93 ? 489 GLN B NE2 1 ATOM 5502 N N . PRO B 1 300 ? 72.746 41.754 13.893 1.00 17.84 ? 490 PRO B N 1 ATOM 5503 C CA . PRO B 1 300 ? 72.610 40.303 13.733 1.00 20.52 ? 490 PRO B CA 1 ATOM 5504 C C . PRO B 1 300 ? 73.939 39.585 13.937 1.00 20.75 ? 490 PRO B C 1 ATOM 5505 O O . PRO B 1 300 ? 74.967 39.988 13.392 1.00 20.60 ? 490 PRO B O 1 ATOM 5506 C CB . PRO B 1 300 ? 72.059 40.159 12.313 1.00 19.71 ? 490 PRO B CB 1 ATOM 5507 C CG . PRO B 1 300 ? 72.574 41.373 11.622 1.00 21.11 ? 490 PRO B CG 1 ATOM 5508 C CD . PRO B 1 300 ? 72.369 42.450 12.653 1.00 22.58 ? 490 PRO B CD 1 ATOM 5509 N N . CYS B 1 301 ? 73.904 38.521 14.733 1.00 19.08 ? 491 CYS B N 1 ATOM 5510 C CA . CYS B 1 301 ? 75.099 37.752 15.053 1.00 17.81 ? 491 CYS B CA 1 ATOM 5511 C C . CYS B 1 301 ? 74.885 36.236 14.989 1.00 21.49 ? 491 CYS B C 1 ATOM 5512 O O . CYS B 1 301 ? 73.813 35.763 14.614 1.00 26.52 ? 491 CYS B O 1 ATOM 5513 C CB . CYS B 1 301 ? 75.584 38.156 16.444 1.00 13.16 ? 491 CYS B CB 1 ATOM 5514 S SG . CYS B 1 301 ? 74.242 38.231 17.672 1.00 18.27 ? 491 CYS B SG 1 ATOM 5515 N N . LEU B 1 302 ? 75.917 35.485 15.365 1.00 23.13 ? 492 LEU B N 1 ATOM 5516 C CA . LEU B 1 302 ? 75.887 34.025 15.352 1.00 24.15 ? 492 LEU B CA 1 ATOM 5517 C C . LEU B 1 302 ? 75.249 33.434 14.105 1.00 27.65 ? 492 LEU B C 1 ATOM 5518 O O . LEU B 1 302 ? 74.334 32.615 14.187 1.00 28.39 ? 492 LEU B O 1 ATOM 5519 C CB . LEU B 1 302 ? 75.179 33.485 16.597 1.00 24.52 ? 492 LEU B CB 1 ATOM 5520 C CG . LEU B 1 302 ? 76.044 33.411 17.857 1.00 25.13 ? 492 LEU B CG 1 ATOM 5521 C CD1 . LEU B 1 302 ? 75.223 32.869 19.024 1.00 22.71 ? 492 LEU B CD1 1 ATOM 5522 C CD2 . LEU B 1 302 ? 77.250 32.518 17.586 1.00 13.25 ? 492 LEU B CD2 1 ATOM 5523 N N . ASP B 1 303 ? 75.746 33.855 12.949 1.00 32.50 ? 493 ASP B N 1 ATOM 5524 C CA . ASP B 1 303 ? 75.247 33.367 11.671 1.00 36.50 ? 493 ASP B CA 1 ATOM 5525 C C . ASP B 1 303 ? 73.728 33.506 11.551 1.00 36.73 ? 493 ASP B C 1 ATOM 5526 O O . ASP B 1 303 ? 73.048 32.599 11.073 1.00 38.36 ? 493 ASP B O 1 ATOM 5527 C CB . ASP B 1 303 ? 75.659 31.905 11.479 1.00 39.53 ? 493 ASP B CB 1 ATOM 5528 C CG . ASP B 1 303 ? 75.424 31.412 10.063 1.00 50.25 ? 493 ASP B CG 1 ATOM 5529 O OD1 . ASP B 1 303 ? 75.619 30.202 9.815 1.00 53.70 ? 493 ASP B OD1 1 ATOM 5530 O OD2 . ASP B 1 303 ? 75.048 32.233 9.196 1.00 52.18 ? 493 ASP B OD2 1 ATOM 5531 N N . ASN B 1 304 ? 73.208 34.648 11.994 1.00 36.05 ? 494 ASN B N 1 ATOM 5532 C CA . ASN B 1 304 ? 71.779 34.949 11.930 1.00 37.07 ? 494 ASN B CA 1 ATOM 5533 C C . ASN B 1 304 ? 70.859 34.147 12.848 1.00 36.22 ? 494 ASN B C 1 ATOM 5534 O O . ASN B 1 304 ? 69.696 33.907 12.517 1.00 36.59 ? 494 ASN B O 1 ATOM 5535 C CB . ASN B 1 304 ? 71.291 34.839 10.483 1.00 42.91 ? 494 ASN B CB 1 ATOM 5536 C CG . ASN B 1 304 ? 71.745 36.008 9.630 1.00 51.67 ? 494 ASN B CG 1 ATOM 5537 O OD1 . ASN B 1 304 ? 71.293 37.138 9.819 1.00 58.18 ? 494 ASN B OD1 1 ATOM 5538 N ND2 . ASN B 1 304 ? 72.652 35.746 8.695 1.00 51.87 ? 494 ASN B ND2 1 ATOM 5539 N N . TYR B 1 305 ? 71.375 33.738 14.001 1.00 32.04 ? 495 TYR B N 1 ATOM 5540 C CA . TYR B 1 305 ? 70.570 33.002 14.965 1.00 26.83 ? 495 TYR B CA 1 ATOM 5541 C C . TYR B 1 305 ? 70.220 33.912 16.131 1.00 22.59 ? 495 TYR B C 1 ATOM 5542 O O . TYR B 1 305 ? 69.400 33.564 16.975 1.00 23.31 ? 495 TYR B O 1 ATOM 5543 C CB . TYR B 1 305 ? 71.317 31.768 15.478 1.00 31.30 ? 495 TYR B CB 1 ATOM 5544 C CG . TYR B 1 305 ? 71.074 30.511 14.669 1.00 38.29 ? 495 TYR B CG 1 ATOM 5545 C CD1 . TYR B 1 305 ? 71.508 29.270 15.132 1.00 44.99 ? 495 TYR B CD1 1 ATOM 5546 C CD2 . TYR B 1 305 ? 70.396 30.557 13.450 1.00 44.77 ? 495 TYR B CD2 1 ATOM 5547 C CE1 . TYR B 1 305 ? 71.272 28.106 14.402 1.00 46.50 ? 495 TYR B CE1 1 ATOM 5548 C CE2 . TYR B 1 305 ? 70.156 29.400 12.715 1.00 44.18 ? 495 TYR B CE2 1 ATOM 5549 C CZ . TYR B 1 305 ? 70.597 28.180 13.197 1.00 44.22 ? 495 TYR B CZ 1 ATOM 5550 O OH . TYR B 1 305 ? 70.368 27.035 12.473 1.00 46.98 ? 495 TYR B OH 1 ATOM 5551 N N . GLY B 1 306 ? 70.846 35.083 16.171 1.00 19.45 ? 496 GLY B N 1 ATOM 5552 C CA . GLY B 1 306 ? 70.576 36.024 17.241 1.00 22.32 ? 496 GLY B CA 1 ATOM 5553 C C . GLY B 1 306 ? 70.973 37.448 16.901 1.00 25.18 ? 496 GLY B C 1 ATOM 5554 O O . GLY B 1 306 ? 71.563 37.707 15.853 1.00 30.25 ? 496 GLY B O 1 ATOM 5555 N N . TYR B 1 307 ? 70.632 38.379 17.785 1.00 24.60 ? 497 TYR B N 1 ATOM 5556 C CA . TYR B 1 307 ? 70.979 39.781 17.594 1.00 24.46 ? 497 TYR B CA 1 ATOM 5557 C C . TYR B 1 307 ? 71.772 40.250 18.804 1.00 24.61 ? 497 TYR B C 1 ATOM 5558 O O . TYR B 1 307 ? 71.417 39.945 19.943 1.00 32.99 ? 497 TYR B O 1 ATOM 5559 C CB . TYR B 1 307 ? 69.728 40.647 17.449 1.00 19.43 ? 497 TYR B CB 1 ATOM 5560 C CG . TYR B 1 307 ? 68.820 40.241 16.313 1.00 17.93 ? 497 TYR B CG 1 ATOM 5561 C CD1 . TYR B 1 307 ? 67.685 39.467 16.543 1.00 19.22 ? 497 TYR B CD1 1 ATOM 5562 C CD2 . TYR B 1 307 ? 69.092 40.640 15.005 1.00 16.15 ? 497 TYR B CD2 1 ATOM 5563 C CE1 . TYR B 1 307 ? 66.839 39.105 15.499 1.00 18.91 ? 497 TYR B CE1 1 ATOM 5564 C CE2 . TYR B 1 307 ? 68.257 40.282 13.957 1.00 10.53 ? 497 TYR B CE2 1 ATOM 5565 C CZ . TYR B 1 307 ? 67.133 39.518 14.208 1.00 16.24 ? 497 TYR B CZ 1 ATOM 5566 O OH . TYR B 1 307 ? 66.295 39.179 13.170 1.00 21.11 ? 497 TYR B OH 1 ATOM 5567 N N . CYS B 1 308 ? 72.843 40.990 18.552 1.00 20.28 ? 498 CYS B N 1 ATOM 5568 C CA . CYS B 1 308 ? 73.694 41.502 19.613 1.00 16.20 ? 498 CYS B CA 1 ATOM 5569 C C . CYS B 1 308 ? 72.944 42.234 20.711 1.00 14.80 ? 498 CYS B C 1 ATOM 5570 O O . CYS B 1 308 ? 71.943 42.909 20.466 1.00 11.06 ? 498 CYS B O 1 ATOM 5571 C CB . CYS B 1 308 ? 74.740 42.458 19.041 1.00 20.46 ? 498 CYS B CB 1 ATOM 5572 S SG . CYS B 1 308 ? 76.024 41.680 18.018 1.00 30.65 ? 498 CYS B SG 1 ATOM 5573 N N . TYR B 1 309 ? 73.451 42.096 21.930 1.00 16.46 ? 499 TYR B N 1 ATOM 5574 C CA . TYR B 1 309 ? 72.885 42.768 23.088 1.00 17.34 ? 499 TYR B CA 1 ATOM 5575 C C . TYR B 1 309 ? 74.007 42.948 24.095 1.00 15.67 ? 499 TYR B C 1 ATOM 5576 O O . TYR B 1 309 ? 74.583 41.973 24.573 1.00 15.59 ? 499 TYR B O 1 ATOM 5577 C CB . TYR B 1 309 ? 71.756 41.955 23.719 1.00 19.91 ? 499 TYR B CB 1 ATOM 5578 C CG . TYR B 1 309 ? 71.143 42.665 24.903 1.00 20.86 ? 499 TYR B CG 1 ATOM 5579 C CD1 . TYR B 1 309 ? 70.478 43.883 24.740 1.00 16.38 ? 499 TYR B CD1 1 ATOM 5580 C CD2 . TYR B 1 309 ? 71.271 42.150 26.192 1.00 22.24 ? 499 TYR B CD2 1 ATOM 5581 C CE1 . TYR B 1 309 ? 69.962 44.571 25.832 1.00 21.27 ? 499 TYR B CE1 1 ATOM 5582 C CE2 . TYR B 1 309 ? 70.756 42.830 27.293 1.00 26.42 ? 499 TYR B CE2 1 ATOM 5583 C CZ . TYR B 1 309 ? 70.104 44.040 27.108 1.00 27.54 ? 499 TYR B CZ 1 ATOM 5584 O OH . TYR B 1 309 ? 69.605 44.720 28.200 1.00 28.33 ? 499 TYR B OH 1 ATOM 5585 N N . ASN B 1 310 ? 74.317 44.203 24.399 1.00 15.16 ? 500 ASN B N 1 ATOM 5586 C CA . ASN B 1 310 ? 75.382 44.546 25.333 1.00 16.64 ? 500 ASN B CA 1 ATOM 5587 C C . ASN B 1 310 ? 76.652 43.692 25.245 1.00 15.74 ? 500 ASN B C 1 ATOM 5588 O O . ASN B 1 310 ? 77.195 43.255 26.259 1.00 18.16 ? 500 ASN B O 1 ATOM 5589 C CB . ASN B 1 310 ? 74.845 44.532 26.757 1.00 17.60 ? 500 ASN B CB 1 ATOM 5590 C CG . ASN B 1 310 ? 73.728 45.525 26.952 1.00 28.01 ? 500 ASN B CG 1 ATOM 5591 O OD1 . ASN B 1 310 ? 73.779 46.638 26.431 1.00 28.49 ? 500 ASN B OD1 1 ATOM 5592 N ND2 . ASN B 1 310 ? 72.711 45.135 27.711 1.00 34.75 ? 500 ASN B ND2 1 ATOM 5593 N N . GLY B 1 311 ? 77.121 43.457 24.025 1.00 13.28 ? 501 GLY B N 1 ATOM 5594 C CA . GLY B 1 311 ? 78.341 42.695 23.843 1.00 15.18 ? 501 GLY B CA 1 ATOM 5595 C C . GLY B 1 311 ? 78.230 41.191 23.719 1.00 15.64 ? 501 GLY B C 1 ATOM 5596 O O . GLY B 1 311 ? 79.250 40.500 23.721 1.00 19.58 ? 501 GLY B O 1 ATOM 5597 N N . ASN B 1 312 ? 77.012 40.672 23.614 1.00 18.79 ? 502 ASN B N 1 ATOM 5598 C CA . ASN B 1 312 ? 76.826 39.230 23.482 1.00 20.96 ? 502 ASN B CA 1 ATOM 5599 C C . ASN B 1 312 ? 75.740 38.894 22.469 1.00 18.33 ? 502 ASN B C 1 ATOM 5600 O O . ASN B 1 312 ? 74.979 39.761 22.045 1.00 13.83 ? 502 ASN B O 1 ATOM 5601 C CB . ASN B 1 312 ? 76.467 38.602 24.834 1.00 30.28 ? 502 ASN B CB 1 ATOM 5602 C CG . ASN B 1 312 ? 77.548 38.804 25.881 1.00 38.88 ? 502 ASN B CG 1 ATOM 5603 O OD1 . ASN B 1 312 ? 77.774 39.918 26.353 1.00 46.42 ? 502 ASN B OD1 1 ATOM 5604 N ND2 . ASN B 1 312 ? 78.226 37.723 26.245 1.00 45.77 ? 502 ASN B ND2 1 ATOM 5605 N N . CYS B 1 313 ? 75.685 37.625 22.082 1.00 20.06 ? 503 CYS B N 1 ATOM 5606 C CA . CYS B 1 313 ? 74.688 37.156 21.135 1.00 20.26 ? 503 CYS B CA 1 ATOM 5607 C C . CYS B 1 313 ? 73.843 36.097 21.839 1.00 19.70 ? 503 CYS B C 1 ATOM 5608 O O . CYS B 1 313 ? 74.026 34.896 21.627 1.00 24.39 ? 503 CYS B O 1 ATOM 5609 C CB . CYS B 1 313 ? 75.364 36.553 19.904 1.00 19.59 ? 503 CYS B CB 1 ATOM 5610 S SG . CYS B 1 313 ? 74.234 36.374 18.488 1.00 20.53 ? 503 CYS B SG 1 ATOM 5611 N N . PRO B 1 314 ? 72.904 36.534 22.691 1.00 16.20 ? 504 PRO B N 1 ATOM 5612 C CA . PRO B 1 314 ? 72.024 35.632 23.441 1.00 11.47 ? 504 PRO B CA 1 ATOM 5613 C C . PRO B 1 314 ? 71.039 34.843 22.584 1.00 12.29 ? 504 PRO B C 1 ATOM 5614 O O . PRO B 1 314 ? 70.144 35.411 21.961 1.00 14.40 ? 504 PRO B O 1 ATOM 5615 C CB . PRO B 1 314 ? 71.322 36.575 24.415 1.00 13.81 ? 504 PRO B CB 1 ATOM 5616 C CG . PRO B 1 314 ? 71.214 37.847 23.622 1.00 15.28 ? 504 PRO B CG 1 ATOM 5617 C CD . PRO B 1 314 ? 72.585 37.945 22.985 1.00 14.88 ? 504 PRO B CD 1 ATOM 5618 N N . ILE B 1 315 ? 71.204 33.528 22.550 1.00 11.91 ? 505 ILE B N 1 ATOM 5619 C CA . ILE B 1 315 ? 70.300 32.696 21.775 1.00 14.94 ? 505 ILE B CA 1 ATOM 5620 C C . ILE B 1 315 ? 69.776 31.512 22.582 1.00 18.37 ? 505 ILE B C 1 ATOM 5621 O O . ILE B 1 315 ? 70.484 30.939 23.415 1.00 16.20 ? 505 ILE B O 1 ATOM 5622 C CB . ILE B 1 315 ? 70.964 32.163 20.483 1.00 14.36 ? 505 ILE B CB 1 ATOM 5623 C CG1 . ILE B 1 315 ? 72.110 31.212 20.828 1.00 16.65 ? 505 ILE B CG1 1 ATOM 5624 C CG2 . ILE B 1 315 ? 71.463 33.323 19.645 1.00 16.79 ? 505 ILE B CG2 1 ATOM 5625 C CD1 . ILE B 1 315 ? 72.646 30.453 19.633 1.00 11.65 ? 505 ILE B CD1 1 ATOM 5626 N N . MET B 1 316 ? 68.519 31.168 22.318 1.00 17.88 ? 506 MET B N 1 ATOM 5627 C CA . MET B 1 316 ? 67.824 30.071 22.973 1.00 15.41 ? 506 MET B CA 1 ATOM 5628 C C . MET B 1 316 ? 68.704 28.834 23.174 1.00 15.52 ? 506 MET B C 1 ATOM 5629 O O . MET B 1 316 ? 68.771 28.284 24.271 1.00 17.47 ? 506 MET B O 1 ATOM 5630 C CB . MET B 1 316 ? 66.591 29.692 22.145 1.00 20.39 ? 506 MET B CB 1 ATOM 5631 C CG . MET B 1 316 ? 65.312 29.542 22.945 1.00 22.43 ? 506 MET B CG 1 ATOM 5632 S SD . MET B 1 316 ? 64.719 31.116 23.537 1.00 20.65 ? 506 MET B SD 1 ATOM 5633 C CE . MET B 1 316 ? 63.108 31.181 22.777 1.00 31.94 ? 506 MET B CE 1 ATOM 5634 N N . TYR B 1 317 ? 69.384 28.405 22.116 1.00 18.06 ? 507 TYR B N 1 ATOM 5635 C CA . TYR B 1 317 ? 70.242 27.221 22.175 1.00 19.59 ? 507 TYR B CA 1 ATOM 5636 C C . TYR B 1 317 ? 71.368 27.285 23.213 1.00 20.30 ? 507 TYR B C 1 ATOM 5637 O O . TYR B 1 317 ? 71.517 26.367 24.015 1.00 24.21 ? 507 TYR B O 1 ATOM 5638 C CB . TYR B 1 317 ? 70.830 26.934 20.789 1.00 23.30 ? 507 TYR B CB 1 ATOM 5639 C CG . TYR B 1 317 ? 71.791 25.766 20.753 1.00 29.61 ? 507 TYR B CG 1 ATOM 5640 C CD1 . TYR B 1 317 ? 71.362 24.473 21.046 1.00 27.45 ? 507 TYR B CD1 1 ATOM 5641 C CD2 . TYR B 1 317 ? 73.137 25.958 20.445 1.00 31.94 ? 507 TYR B CD2 1 ATOM 5642 C CE1 . TYR B 1 317 ? 72.250 23.402 21.033 1.00 23.53 ? 507 TYR B CE1 1 ATOM 5643 C CE2 . TYR B 1 317 ? 74.030 24.897 20.431 1.00 27.23 ? 507 TYR B CE2 1 ATOM 5644 C CZ . TYR B 1 317 ? 73.583 23.622 20.725 1.00 29.41 ? 507 TYR B CZ 1 ATOM 5645 O OH . TYR B 1 317 ? 74.475 22.569 20.713 1.00 34.48 ? 507 TYR B OH 1 ATOM 5646 N N . HIS B 1 318 ? 72.162 28.352 23.203 1.00 18.34 ? 508 HIS B N 1 ATOM 5647 C CA . HIS B 1 318 ? 73.257 28.466 24.164 1.00 20.36 ? 508 HIS B CA 1 ATOM 5648 C C . HIS B 1 318 ? 72.754 28.558 25.598 1.00 20.98 ? 508 HIS B C 1 ATOM 5649 O O . HIS B 1 318 ? 73.395 28.055 26.522 1.00 20.39 ? 508 HIS B O 1 ATOM 5650 C CB . HIS B 1 318 ? 74.135 29.690 23.875 1.00 20.23 ? 508 HIS B CB 1 ATOM 5651 C CG . HIS B 1 318 ? 74.973 29.560 22.643 1.00 21.79 ? 508 HIS B CG 1 ATOM 5652 N ND1 . HIS B 1 318 ? 75.534 28.366 22.246 1.00 23.39 ? 508 HIS B ND1 1 ATOM 5653 C CD2 . HIS B 1 318 ? 75.362 30.481 21.730 1.00 20.73 ? 508 HIS B CD2 1 ATOM 5654 C CE1 . HIS B 1 318 ? 76.229 28.555 21.139 1.00 23.25 ? 508 HIS B CE1 1 ATOM 5655 N NE2 . HIS B 1 318 ? 76.141 29.829 20.805 1.00 20.82 ? 508 HIS B NE2 1 ATOM 5656 N N . GLN B 1 319 ? 71.611 29.208 25.785 1.00 20.98 ? 509 GLN B N 1 ATOM 5657 C CA . GLN B 1 319 ? 71.050 29.357 27.119 1.00 20.53 ? 509 GLN B CA 1 ATOM 5658 C C . GLN B 1 319 ? 70.616 28.006 27.682 1.00 20.58 ? 509 GLN B C 1 ATOM 5659 O O . GLN B 1 319 ? 70.700 27.774 28.887 1.00 19.04 ? 509 GLN B O 1 ATOM 5660 C CB . GLN B 1 319 ? 69.891 30.353 27.086 1.00 20.35 ? 509 GLN B CB 1 ATOM 5661 C CG . GLN B 1 319 ? 70.356 31.777 26.823 1.00 20.68 ? 509 GLN B CG 1 ATOM 5662 C CD . GLN B 1 319 ? 69.212 32.755 26.630 1.00 24.74 ? 509 GLN B CD 1 ATOM 5663 O OE1 . GLN B 1 319 ? 68.347 32.895 27.495 1.00 20.79 ? 509 GLN B OE1 1 ATOM 5664 N NE2 . GLN B 1 319 ? 69.207 33.442 25.491 1.00 17.96 ? 509 GLN B NE2 1 ATOM 5665 N N . CYS B 1 320 ? 70.155 27.115 26.809 1.00 22.23 ? 510 CYS B N 1 ATOM 5666 C CA . CYS B 1 320 ? 69.762 25.780 27.241 1.00 25.38 ? 510 CYS B CA 1 ATOM 5667 C C . CYS B 1 320 ? 71.037 25.024 27.608 1.00 28.52 ? 510 CYS B C 1 ATOM 5668 O O . CYS B 1 320 ? 71.068 24.267 28.577 1.00 32.63 ? 510 CYS B O 1 ATOM 5669 C CB . CYS B 1 320 ? 69.030 25.032 26.123 1.00 23.52 ? 510 CYS B CB 1 ATOM 5670 S SG . CYS B 1 320 ? 67.277 25.483 25.910 1.00 28.03 ? 510 CYS B SG 1 ATOM 5671 N N . TYR B 1 321 ? 72.092 25.242 26.825 1.00 26.51 ? 511 TYR B N 1 ATOM 5672 C CA . TYR B 1 321 ? 73.372 24.595 27.071 1.00 24.05 ? 511 TYR B CA 1 ATOM 5673 C C . TYR B 1 321 ? 73.936 24.989 28.431 1.00 23.35 ? 511 TYR B C 1 ATOM 5674 O O . TYR B 1 321 ? 74.342 24.127 29.210 1.00 24.49 ? 511 TYR B O 1 ATOM 5675 C CB . TYR B 1 321 ? 74.369 24.949 25.961 1.00 28.69 ? 511 TYR B CB 1 ATOM 5676 C CG . TYR B 1 321 ? 75.805 24.576 26.271 1.00 31.10 ? 511 TYR B CG 1 ATOM 5677 C CD1 . TYR B 1 321 ? 76.610 25.413 27.045 1.00 37.90 ? 511 TYR B CD1 1 ATOM 5678 C CD2 . TYR B 1 321 ? 76.348 23.374 25.817 1.00 30.30 ? 511 TYR B CD2 1 ATOM 5679 C CE1 . TYR B 1 321 ? 77.917 25.064 27.363 1.00 36.76 ? 511 TYR B CE1 1 ATOM 5680 C CE2 . TYR B 1 321 ? 77.654 23.014 26.130 1.00 32.38 ? 511 TYR B CE2 1 ATOM 5681 C CZ . TYR B 1 321 ? 78.433 23.865 26.905 1.00 39.97 ? 511 TYR B CZ 1 ATOM 5682 O OH . TYR B 1 321 ? 79.726 23.521 27.228 1.00 46.93 ? 511 TYR B OH 1 ATOM 5683 N N . ASP B 1 322 ? 73.972 26.287 28.718 1.00 23.78 ? 512 ASP B N 1 ATOM 5684 C CA . ASP B 1 322 ? 74.490 26.744 30.003 1.00 26.44 ? 512 ASP B CA 1 ATOM 5685 C C . ASP B 1 322 ? 73.764 26.031 31.137 1.00 28.97 ? 512 ASP B C 1 ATOM 5686 O O . ASP B 1 322 ? 74.384 25.606 32.115 1.00 31.44 ? 512 ASP B O 1 ATOM 5687 C CB . ASP B 1 322 ? 74.313 28.259 30.172 1.00 26.54 ? 512 ASP B CB 1 ATOM 5688 C CG . ASP B 1 322 ? 75.166 29.062 29.208 1.00 31.55 ? 512 ASP B CG 1 ATOM 5689 O OD1 . ASP B 1 322 ? 76.345 28.699 29.004 1.00 33.61 ? 512 ASP B OD1 1 ATOM 5690 O OD2 . ASP B 1 322 ? 74.661 30.069 28.666 1.00 34.52 ? 512 ASP B OD2 1 ATOM 5691 N N . LEU B 1 323 ? 72.450 25.891 30.992 1.00 25.50 ? 513 LEU B N 1 ATOM 5692 C CA . LEU B 1 323 ? 71.634 25.247 32.008 1.00 25.91 ? 513 LEU B CA 1 ATOM 5693 C C . LEU B 1 323 ? 71.779 23.736 32.156 1.00 25.60 ? 513 LEU B C 1 ATOM 5694 O O . LEU B 1 323 ? 72.163 23.259 33.220 1.00 29.21 ? 513 LEU B O 1 ATOM 5695 C CB . LEU B 1 323 ? 70.159 25.579 31.787 1.00 25.66 ? 513 LEU B CB 1 ATOM 5696 C CG . LEU B 1 323 ? 69.712 26.978 32.206 1.00 23.77 ? 513 LEU B CG 1 ATOM 5697 C CD1 . LEU B 1 323 ? 68.215 27.117 31.963 1.00 17.97 ? 513 LEU B CD1 1 ATOM 5698 C CD2 . LEU B 1 323 ? 70.045 27.207 33.675 1.00 13.25 ? 513 LEU B CD2 1 ATOM 5699 N N . PHE B 1 324 ? 71.477 22.984 31.102 1.00 24.10 ? 514 PHE B N 1 ATOM 5700 C CA . PHE B 1 324 ? 71.547 21.529 31.187 1.00 23.74 ? 514 PHE B CA 1 ATOM 5701 C C . PHE B 1 324 ? 72.683 20.849 30.425 1.00 23.70 ? 514 PHE B C 1 ATOM 5702 O O . PHE B 1 324 ? 72.602 19.656 30.126 1.00 24.22 ? 514 PHE B O 1 ATOM 5703 C CB . PHE B 1 324 ? 70.213 20.927 30.742 1.00 22.37 ? 514 PHE B CB 1 ATOM 5704 C CG . PHE B 1 324 ? 69.016 21.723 31.175 1.00 26.92 ? 514 PHE B CG 1 ATOM 5705 C CD1 . PHE B 1 324 ? 68.410 22.621 30.299 1.00 28.40 ? 514 PHE B CD1 1 ATOM 5706 C CD2 . PHE B 1 324 ? 68.505 21.593 32.461 1.00 27.86 ? 514 PHE B CD2 1 ATOM 5707 C CE1 . PHE B 1 324 ? 67.311 23.379 30.697 1.00 24.79 ? 514 PHE B CE1 1 ATOM 5708 C CE2 . PHE B 1 324 ? 67.405 22.347 32.872 1.00 27.19 ? 514 PHE B CE2 1 ATOM 5709 C CZ . PHE B 1 324 ? 66.807 23.242 31.987 1.00 29.37 ? 514 PHE B CZ 1 ATOM 5710 N N . GLY B 1 325 ? 73.738 21.593 30.113 1.00 23.41 ? 515 GLY B N 1 ATOM 5711 C CA . GLY B 1 325 ? 74.858 21.002 29.401 1.00 23.49 ? 515 GLY B CA 1 ATOM 5712 C C . GLY B 1 325 ? 74.668 20.870 27.901 1.00 29.74 ? 515 GLY B C 1 ATOM 5713 O O . GLY B 1 325 ? 74.135 21.769 27.253 1.00 35.53 ? 515 GLY B O 1 ATOM 5714 N N . ALA B 1 326 ? 75.096 19.740 27.345 1.00 34.44 ? 516 ALA B N 1 ATOM 5715 C CA . ALA B 1 326 ? 74.992 19.506 25.906 1.00 35.83 ? 516 ALA B CA 1 ATOM 5716 C C . ALA B 1 326 ? 73.863 18.561 25.511 1.00 37.14 ? 516 ALA B C 1 ATOM 5717 O O . ALA B 1 326 ? 73.271 17.892 26.357 1.00 39.44 ? 516 ALA B O 1 ATOM 5718 C CB . ALA B 1 326 ? 76.320 18.974 25.377 1.00 34.38 ? 516 ALA B CB 1 ATOM 5719 N N . ASP B 1 327 ? 73.578 18.517 24.211 1.00 39.40 ? 517 ASP B N 1 ATOM 5720 C CA . ASP B 1 327 ? 72.531 17.662 23.659 1.00 42.93 ? 517 ASP B CA 1 ATOM 5721 C C . ASP B 1 327 ? 71.127 18.069 24.115 1.00 42.49 ? 517 ASP B C 1 ATOM 5722 O O . ASP B 1 327 ? 70.180 17.287 24.017 1.00 40.48 ? 517 ASP B O 1 ATOM 5723 C CB . ASP B 1 327 ? 72.796 16.198 24.028 1.00 51.12 ? 517 ASP B CB 1 ATOM 5724 C CG . ASP B 1 327 ? 71.810 15.243 23.374 1.00 60.17 ? 517 ASP B CG 1 ATOM 5725 O OD1 . ASP B 1 327 ? 71.771 15.187 22.125 1.00 61.79 ? 517 ASP B OD1 1 ATOM 5726 O OD2 . ASP B 1 327 ? 71.074 14.549 24.110 1.00 63.11 ? 517 ASP B OD2 1 ATOM 5727 N N . VAL B 1 328 ? 70.998 19.294 24.616 1.00 42.85 ? 518 VAL B N 1 ATOM 5728 C CA . VAL B 1 328 ? 69.706 19.812 25.063 1.00 40.61 ? 518 VAL B CA 1 ATOM 5729 C C . VAL B 1 328 ? 69.370 21.037 24.214 1.00 40.69 ? 518 VAL B C 1 ATOM 5730 O O . VAL B 1 328 ? 69.996 22.087 24.357 1.00 44.37 ? 518 VAL B O 1 ATOM 5731 C CB . VAL B 1 328 ? 69.746 20.224 26.549 1.00 37.12 ? 518 VAL B CB 1 ATOM 5732 C CG1 . VAL B 1 328 ? 68.388 20.758 26.974 1.00 41.35 ? 518 VAL B CG1 1 ATOM 5733 C CG2 . VAL B 1 328 ? 70.137 19.038 27.408 1.00 32.21 ? 518 VAL B CG2 1 ATOM 5734 N N . TYR B 1 329 ? 68.382 20.903 23.335 1.00 38.00 ? 519 TYR B N 1 ATOM 5735 C CA . TYR B 1 329 ? 68.003 21.998 22.448 1.00 38.16 ? 519 TYR B CA 1 ATOM 5736 C C . TYR B 1 329 ? 66.731 22.720 22.870 1.00 39.14 ? 519 TYR B C 1 ATOM 5737 O O . TYR B 1 329 ? 66.068 22.319 23.825 1.00 38.87 ? 519 TYR B O 1 ATOM 5738 C CB . TYR B 1 329 ? 67.843 21.468 21.024 1.00 37.03 ? 519 TYR B CB 1 ATOM 5739 C CG . TYR B 1 329 ? 68.915 20.475 20.646 1.00 40.72 ? 519 TYR B CG 1 ATOM 5740 C CD1 . TYR B 1 329 ? 68.727 19.107 20.843 1.00 39.16 ? 519 TYR B CD1 1 ATOM 5741 C CD2 . TYR B 1 329 ? 70.137 20.904 20.132 1.00 40.29 ? 519 TYR B CD2 1 ATOM 5742 C CE1 . TYR B 1 329 ? 69.732 18.192 20.537 1.00 37.88 ? 519 TYR B CE1 1 ATOM 5743 C CE2 . TYR B 1 329 ? 71.147 19.999 19.825 1.00 36.90 ? 519 TYR B CE2 1 ATOM 5744 C CZ . TYR B 1 329 ? 70.939 18.648 20.028 1.00 38.06 ? 519 TYR B CZ 1 ATOM 5745 O OH . TYR B 1 329 ? 71.939 17.755 19.720 1.00 44.63 ? 519 TYR B OH 1 ATOM 5746 N N . GLU B 1 330 ? 66.403 23.792 22.153 1.00 38.70 ? 520 GLU B N 1 ATOM 5747 C CA . GLU B 1 330 ? 65.204 24.573 22.444 1.00 35.66 ? 520 GLU B CA 1 ATOM 5748 C C . GLU B 1 330 ? 63.989 23.664 22.348 1.00 34.10 ? 520 GLU B C 1 ATOM 5749 O O . GLU B 1 330 ? 63.886 22.848 21.433 1.00 36.29 ? 520 GLU B O 1 ATOM 5750 C CB . GLU B 1 330 ? 65.050 25.727 21.443 1.00 34.41 ? 520 GLU B CB 1 ATOM 5751 C CG . GLU B 1 330 ? 63.899 26.683 21.770 1.00 36.03 ? 520 GLU B CG 1 ATOM 5752 C CD . GLU B 1 330 ? 63.680 27.753 20.708 1.00 34.92 ? 520 GLU B CD 1 ATOM 5753 O OE1 . GLU B 1 330 ? 64.684 28.303 20.205 1.00 35.28 ? 520 GLU B OE1 1 ATOM 5754 O OE2 . GLU B 1 330 ? 62.505 28.053 20.387 1.00 28.87 ? 520 GLU B OE2 1 ATOM 5755 N N . ALA B 1 331 ? 63.074 23.800 23.299 1.00 32.22 ? 521 ALA B N 1 ATOM 5756 C CA . ALA B 1 331 ? 61.866 22.991 23.302 1.00 33.72 ? 521 ALA B CA 1 ATOM 5757 C C . ALA B 1 331 ? 60.870 23.558 22.294 1.00 36.81 ? 521 ALA B C 1 ATOM 5758 O O . ALA B 1 331 ? 60.953 24.729 21.916 1.00 32.61 ? 521 ALA B O 1 ATOM 5759 C CB . ALA B 1 331 ? 61.256 22.976 24.696 1.00 33.26 ? 521 ALA B CB 1 ATOM 5760 N N . GLU B 1 332 ? 59.929 22.725 21.860 1.00 40.49 ? 522 GLU B N 1 ATOM 5761 C CA . GLU B 1 332 ? 58.921 23.151 20.898 1.00 40.95 ? 522 GLU B CA 1 ATOM 5762 C C . GLU B 1 332 ? 58.070 24.310 21.411 1.00 38.89 ? 522 GLU B C 1 ATOM 5763 O O . GLU B 1 332 ? 57.993 24.556 22.616 1.00 37.65 ? 522 GLU B O 1 ATOM 5764 C CB . GLU B 1 332 ? 58.023 21.972 20.517 1.00 46.44 ? 522 GLU B CB 1 ATOM 5765 C CG . GLU B 1 332 ? 58.706 20.957 19.617 1.00 55.60 ? 522 GLU B CG 1 ATOM 5766 C CD . GLU B 1 332 ? 59.276 21.592 18.357 1.00 62.46 ? 522 GLU B CD 1 ATOM 5767 O OE1 . GLU B 1 332 ? 58.503 22.220 17.602 1.00 66.58 ? 522 GLU B OE1 1 ATOM 5768 O OE2 . GLU B 1 332 ? 60.498 21.465 18.122 1.00 66.15 ? 522 GLU B OE2 1 ATOM 5769 N N . ASP B 1 333 ? 57.434 25.013 20.477 1.00 35.68 ? 523 ASP B N 1 ATOM 5770 C CA . ASP B 1 333 ? 56.590 26.163 20.782 1.00 30.53 ? 523 ASP B CA 1 ATOM 5771 C C . ASP B 1 333 ? 55.512 25.921 21.833 1.00 32.68 ? 523 ASP B C 1 ATOM 5772 O O . ASP B 1 333 ? 55.209 26.811 22.626 1.00 38.63 ? 523 ASP B O 1 ATOM 5773 C CB . ASP B 1 333 ? 55.922 26.667 19.501 1.00 32.38 ? 523 ASP B CB 1 ATOM 5774 C CG . ASP B 1 333 ? 56.903 27.299 18.537 1.00 36.16 ? 523 ASP B CG 1 ATOM 5775 O OD1 . ASP B 1 333 ? 57.955 26.684 18.259 1.00 43.67 ? 523 ASP B OD1 1 ATOM 5776 O OD2 . ASP B 1 333 ? 56.616 28.411 18.048 1.00 34.30 ? 523 ASP B OD2 1 ATOM 5777 N N . SER B 1 334 ? 54.927 24.728 21.844 1.00 31.81 ? 524 SER B N 1 ATOM 5778 C CA . SER B 1 334 ? 53.867 24.425 22.804 1.00 34.55 ? 524 SER B CA 1 ATOM 5779 C C . SER B 1 334 ? 54.319 24.520 24.263 1.00 32.53 ? 524 SER B C 1 ATOM 5780 O O . SER B 1 334 ? 53.542 24.906 25.139 1.00 33.32 ? 524 SER B O 1 ATOM 5781 C CB . SER B 1 334 ? 53.286 23.033 22.534 1.00 32.07 ? 524 SER B CB 1 ATOM 5782 O OG . SER B 1 334 ? 54.256 22.024 22.744 1.00 36.06 ? 524 SER B OG 1 ATOM 5783 N N . CYS B 1 335 ? 55.572 24.167 24.524 1.00 26.85 ? 525 CYS B N 1 ATOM 5784 C CA . CYS B 1 335 ? 56.094 24.219 25.881 1.00 24.05 ? 525 CYS B CA 1 ATOM 5785 C C . CYS B 1 335 ? 55.991 25.624 26.453 1.00 24.33 ? 525 CYS B C 1 ATOM 5786 O O . CYS B 1 335 ? 55.529 25.820 27.578 1.00 25.42 ? 525 CYS B O 1 ATOM 5787 C CB . CYS B 1 335 ? 57.560 23.788 25.914 1.00 28.71 ? 525 CYS B CB 1 ATOM 5788 S SG . CYS B 1 335 ? 57.904 22.006 25.737 1.00 34.77 ? 525 CYS B SG 1 ATOM 5789 N N . PHE B 1 336 ? 56.426 26.601 25.667 1.00 24.43 ? 526 PHE B N 1 ATOM 5790 C CA . PHE B 1 336 ? 56.415 27.986 26.103 1.00 20.83 ? 526 PHE B CA 1 ATOM 5791 C C . PHE B 1 336 ? 55.061 28.512 26.552 1.00 20.84 ? 526 PHE B C 1 ATOM 5792 O O . PHE B 1 336 ? 54.997 29.483 27.304 1.00 13.20 ? 526 PHE B O 1 ATOM 5793 C CB . PHE B 1 336 ? 57.001 28.880 25.009 1.00 21.06 ? 526 PHE B CB 1 ATOM 5794 C CG . PHE B 1 336 ? 58.477 28.682 24.803 1.00 17.53 ? 526 PHE B CG 1 ATOM 5795 C CD1 . PHE B 1 336 ? 58.950 27.607 24.062 1.00 14.64 ? 526 PHE B CD1 1 ATOM 5796 C CD2 . PHE B 1 336 ? 59.394 29.545 25.393 1.00 12.49 ? 526 PHE B CD2 1 ATOM 5797 C CE1 . PHE B 1 336 ? 60.315 27.393 23.913 1.00 16.90 ? 526 PHE B CE1 1 ATOM 5798 C CE2 . PHE B 1 336 ? 60.761 29.339 25.251 1.00 15.63 ? 526 PHE B CE2 1 ATOM 5799 C CZ . PHE B 1 336 ? 61.223 28.260 24.510 1.00 17.14 ? 526 PHE B CZ 1 ATOM 5800 N N . GLU B 1 337 ? 53.983 27.871 26.105 1.00 25.14 ? 527 GLU B N 1 ATOM 5801 C CA . GLU B 1 337 ? 52.638 28.289 26.491 1.00 27.49 ? 527 GLU B CA 1 ATOM 5802 C C . GLU B 1 337 ? 52.504 28.308 28.011 1.00 25.94 ? 527 GLU B C 1 ATOM 5803 O O . GLU B 1 337 ? 51.735 29.098 28.563 1.00 28.09 ? 527 GLU B O 1 ATOM 5804 C CB . GLU B 1 337 ? 51.591 27.343 25.897 1.00 36.02 ? 527 GLU B CB 1 ATOM 5805 C CG . GLU B 1 337 ? 51.537 27.347 24.378 1.00 49.50 ? 527 GLU B CG 1 ATOM 5806 C CD . GLU B 1 337 ? 50.574 26.312 23.827 1.00 56.48 ? 527 GLU B CD 1 ATOM 5807 O OE1 . GLU B 1 337 ? 50.500 26.168 22.587 1.00 61.49 ? 527 GLU B OE1 1 ATOM 5808 O OE2 . GLU B 1 337 ? 49.892 25.641 24.632 1.00 56.68 ? 527 GLU B OE2 1 ATOM 5809 N N . ARG B 1 338 ? 53.251 27.432 28.681 1.00 23.33 ? 528 ARG B N 1 ATOM 5810 C CA . ARG B 1 338 ? 53.228 27.356 30.142 1.00 23.54 ? 528 ARG B CA 1 ATOM 5811 C C . ARG B 1 338 ? 53.396 28.749 30.740 1.00 25.64 ? 528 ARG B C 1 ATOM 5812 O O . ARG B 1 338 ? 52.763 29.091 31.739 1.00 24.11 ? 528 ARG B O 1 ATOM 5813 C CB . ARG B 1 338 ? 54.367 26.469 30.658 1.00 24.47 ? 528 ARG B CB 1 ATOM 5814 C CG . ARG B 1 338 ? 54.149 24.960 30.591 1.00 25.81 ? 528 ARG B CG 1 ATOM 5815 C CD . ARG B 1 338 ? 55.394 24.258 31.131 1.00 34.45 ? 528 ARG B CD 1 ATOM 5816 N NE . ARG B 1 338 ? 55.235 22.823 31.372 1.00 41.87 ? 528 ARG B NE 1 ATOM 5817 C CZ . ARG B 1 338 ? 54.931 21.925 30.440 1.00 45.62 ? 528 ARG B CZ 1 ATOM 5818 N NH1 . ARG B 1 338 ? 54.740 22.301 29.183 1.00 50.01 ? 528 ARG B NH1 1 ATOM 5819 N NH2 . ARG B 1 338 ? 54.838 20.641 30.762 1.00 42.81 ? 528 ARG B NH2 1 ATOM 5820 N N . ASN B 1 339 ? 54.256 29.548 30.114 1.00 24.43 ? 529 ASN B N 1 ATOM 5821 C CA . ASN B 1 339 ? 54.545 30.900 30.576 1.00 22.78 ? 529 ASN B CA 1 ATOM 5822 C C . ASN B 1 339 ? 53.328 31.811 30.712 1.00 21.96 ? 529 ASN B C 1 ATOM 5823 O O . ASN B 1 339 ? 53.454 32.951 31.169 1.00 17.26 ? 529 ASN B O 1 ATOM 5824 C CB . ASN B 1 339 ? 55.590 31.546 29.658 1.00 19.83 ? 529 ASN B CB 1 ATOM 5825 C CG . ASN B 1 339 ? 56.992 30.999 29.895 1.00 25.30 ? 529 ASN B CG 1 ATOM 5826 O OD1 . ASN B 1 339 ? 57.908 31.225 29.100 1.00 24.63 ? 529 ASN B OD1 1 ATOM 5827 N ND2 . ASN B 1 339 ? 57.166 30.284 31.000 1.00 20.95 ? 529 ASN B ND2 1 ATOM 5828 N N . GLN B 1 340 ? 52.153 31.315 30.329 1.00 19.63 ? 530 GLN B N 1 ATOM 5829 C CA . GLN B 1 340 ? 50.931 32.115 30.433 1.00 22.62 ? 530 GLN B CA 1 ATOM 5830 C C . GLN B 1 340 ? 50.211 31.886 31.753 1.00 21.42 ? 530 GLN B C 1 ATOM 5831 O O . GLN B 1 340 ? 49.332 32.657 32.124 1.00 24.42 ? 530 GLN B O 1 ATOM 5832 C CB . GLN B 1 340 ? 49.983 31.806 29.274 1.00 17.72 ? 530 GLN B CB 1 ATOM 5833 C CG . GLN B 1 340 ? 50.556 32.166 27.917 1.00 26.45 ? 530 GLN B CG 1 ATOM 5834 C CD . GLN B 1 340 ? 49.582 31.932 26.784 1.00 30.17 ? 530 GLN B CD 1 ATOM 5835 O OE1 . GLN B 1 340 ? 48.578 32.635 26.654 1.00 27.48 ? 530 GLN B OE1 1 ATOM 5836 N NE2 . GLN B 1 340 ? 49.871 30.936 25.954 1.00 33.79 ? 530 GLN B NE2 1 ATOM 5837 N N . LYS B 1 341 ? 50.599 30.831 32.463 1.00 25.68 ? 531 LYS B N 1 ATOM 5838 C CA . LYS B 1 341 ? 49.990 30.493 33.748 1.00 22.87 ? 531 LYS B CA 1 ATOM 5839 C C . LYS B 1 341 ? 50.178 31.600 34.772 1.00 20.69 ? 531 LYS B C 1 ATOM 5840 O O . LYS B 1 341 ? 49.301 31.855 35.592 1.00 23.66 ? 531 LYS B O 1 ATOM 5841 C CB . LYS B 1 341 ? 50.600 29.205 34.308 1.00 23.41 ? 531 LYS B CB 1 ATOM 5842 C CG . LYS B 1 341 ? 50.458 27.990 33.412 1.00 32.40 ? 531 LYS B CG 1 ATOM 5843 C CD . LYS B 1 341 ? 51.152 26.783 34.027 1.00 40.12 ? 531 LYS B CD 1 ATOM 5844 C CE . LYS B 1 341 ? 51.024 25.557 33.139 1.00 41.57 ? 531 LYS B CE 1 ATOM 5845 N NZ . LYS B 1 341 ? 49.598 25.233 32.865 1.00 43.01 ? 531 LYS B NZ 1 ATOM 5846 N N . GLY B 1 342 ? 51.329 32.259 34.726 1.00 21.99 ? 532 GLY B N 1 ATOM 5847 C CA . GLY B 1 342 ? 51.593 33.309 35.687 1.00 21.96 ? 532 GLY B CA 1 ATOM 5848 C C . GLY B 1 342 ? 51.741 32.679 37.059 1.00 25.42 ? 532 GLY B C 1 ATOM 5849 O O . GLY B 1 342 ? 51.397 33.284 38.080 1.00 19.80 ? 532 GLY B O 1 ATOM 5850 N N . ASN B 1 343 ? 52.240 31.444 37.081 1.00 26.27 ? 533 ASN B N 1 ATOM 5851 C CA . ASN B 1 343 ? 52.439 30.738 38.335 1.00 23.81 ? 533 ASN B CA 1 ATOM 5852 C C . ASN B 1 343 ? 53.839 31.024 38.851 1.00 23.78 ? 533 ASN B C 1 ATOM 5853 O O . ASN B 1 343 ? 54.433 32.040 38.498 1.00 26.39 ? 533 ASN B O 1 ATOM 5854 C CB . ASN B 1 343 ? 52.239 29.230 38.160 1.00 21.33 ? 533 ASN B CB 1 ATOM 5855 C CG . ASN B 1 343 ? 53.230 28.620 37.203 1.00 22.33 ? 533 ASN B CG 1 ATOM 5856 O OD1 . ASN B 1 343 ? 54.367 29.074 37.102 1.00 28.31 ? 533 ASN B OD1 1 ATOM 5857 N ND2 . ASN B 1 343 ? 52.812 27.567 36.507 1.00 21.22 ? 533 ASN B ND2 1 ATOM 5858 N N . TYR B 1 344 ? 54.373 30.125 39.672 1.00 24.08 ? 534 TYR B N 1 ATOM 5859 C CA . TYR B 1 344 ? 55.693 30.326 40.250 1.00 20.02 ? 534 TYR B CA 1 ATOM 5860 C C . TYR B 1 344 ? 56.851 30.249 39.262 1.00 20.35 ? 534 TYR B C 1 ATOM 5861 O O . TYR B 1 344 ? 57.848 30.952 39.428 1.00 20.29 ? 534 TYR B O 1 ATOM 5862 C CB . TYR B 1 344 ? 55.916 29.338 41.407 1.00 20.61 ? 534 TYR B CB 1 ATOM 5863 C CG . TYR B 1 344 ? 56.209 27.899 41.012 1.00 20.68 ? 534 TYR B CG 1 ATOM 5864 C CD1 . TYR B 1 344 ? 57.522 27.459 40.808 1.00 13.39 ? 534 TYR B CD1 1 ATOM 5865 C CD2 . TYR B 1 344 ? 55.178 26.968 40.882 1.00 13.95 ? 534 TYR B CD2 1 ATOM 5866 C CE1 . TYR B 1 344 ? 57.796 26.130 40.494 1.00 4.89 ? 534 TYR B CE1 1 ATOM 5867 C CE2 . TYR B 1 344 ? 55.442 25.635 40.565 1.00 4.43 ? 534 TYR B CE2 1 ATOM 5868 C CZ . TYR B 1 344 ? 56.747 25.220 40.376 1.00 14.90 ? 534 TYR B CZ 1 ATOM 5869 O OH . TYR B 1 344 ? 57.000 23.891 40.087 1.00 15.04 ? 534 TYR B OH 1 ATOM 5870 N N . TYR B 1 345 ? 56.724 29.421 38.228 1.00 17.76 ? 535 TYR B N 1 ATOM 5871 C CA . TYR B 1 345 ? 57.807 29.284 37.258 1.00 22.31 ? 535 TYR B CA 1 ATOM 5872 C C . TYR B 1 345 ? 57.546 29.915 35.890 1.00 23.81 ? 535 TYR B C 1 ATOM 5873 O O . TYR B 1 345 ? 58.463 30.473 35.278 1.00 18.50 ? 535 TYR B O 1 ATOM 5874 C CB . TYR B 1 345 ? 58.165 27.801 37.086 1.00 21.26 ? 535 TYR B CB 1 ATOM 5875 C CG . TYR B 1 345 ? 57.178 26.990 36.275 1.00 23.22 ? 535 TYR B CG 1 ATOM 5876 C CD1 . TYR B 1 345 ? 57.205 27.013 34.877 1.00 22.53 ? 535 TYR B CD1 1 ATOM 5877 C CD2 . TYR B 1 345 ? 56.228 26.182 36.902 1.00 23.10 ? 535 TYR B CD2 1 ATOM 5878 C CE1 . TYR B 1 345 ? 56.312 26.248 34.126 1.00 24.19 ? 535 TYR B CE1 1 ATOM 5879 C CE2 . TYR B 1 345 ? 55.330 25.416 36.161 1.00 18.14 ? 535 TYR B CE2 1 ATOM 5880 C CZ . TYR B 1 345 ? 55.378 25.451 34.777 1.00 21.51 ? 535 TYR B CZ 1 ATOM 5881 O OH . TYR B 1 345 ? 54.499 24.687 34.046 1.00 25.96 ? 535 TYR B OH 1 ATOM 5882 N N . GLY B 1 346 ? 56.303 29.821 35.419 1.00 24.88 ? 536 GLY B N 1 ATOM 5883 C CA . GLY B 1 346 ? 55.942 30.370 34.123 1.00 19.25 ? 536 GLY B CA 1 ATOM 5884 C C . GLY B 1 346 ? 55.362 31.770 34.184 1.00 22.31 ? 536 GLY B C 1 ATOM 5885 O O . GLY B 1 346 ? 54.276 31.987 34.717 1.00 24.10 ? 536 GLY B O 1 ATOM 5886 N N . TYR B 1 347 ? 56.096 32.729 33.634 1.00 22.79 ? 537 TYR B N 1 ATOM 5887 C CA . TYR B 1 347 ? 55.656 34.117 33.613 1.00 23.22 ? 537 TYR B CA 1 ATOM 5888 C C . TYR B 1 347 ? 56.608 34.934 32.743 1.00 21.75 ? 537 TYR B C 1 ATOM 5889 O O . TYR B 1 347 ? 57.610 34.412 32.254 1.00 21.67 ? 537 TYR B O 1 ATOM 5890 C CB . TYR B 1 347 ? 55.590 34.673 35.041 1.00 20.27 ? 537 TYR B CB 1 ATOM 5891 C CG . TYR B 1 347 ? 56.905 34.657 35.786 1.00 25.54 ? 537 TYR B CG 1 ATOM 5892 C CD1 . TYR B 1 347 ? 57.806 35.714 35.672 1.00 24.31 ? 537 TYR B CD1 1 ATOM 5893 C CD2 . TYR B 1 347 ? 57.254 33.579 36.604 1.00 26.88 ? 537 TYR B CD2 1 ATOM 5894 C CE1 . TYR B 1 347 ? 59.019 35.702 36.351 1.00 23.01 ? 537 TYR B CE1 1 ATOM 5895 C CE2 . TYR B 1 347 ? 58.468 33.556 37.287 1.00 24.02 ? 537 TYR B CE2 1 ATOM 5896 C CZ . TYR B 1 347 ? 59.346 34.621 37.155 1.00 25.28 ? 537 TYR B CZ 1 ATOM 5897 O OH . TYR B 1 347 ? 60.555 34.607 37.816 1.00 23.23 ? 537 TYR B OH 1 ATOM 5898 N N . CYS B 1 348 ? 56.302 36.210 32.551 1.00 20.41 ? 538 CYS B N 1 ATOM 5899 C CA . CYS B 1 348 ? 57.136 37.055 31.709 1.00 22.81 ? 538 CYS B CA 1 ATOM 5900 C C . CYS B 1 348 ? 58.038 38.057 32.417 1.00 24.83 ? 538 CYS B C 1 ATOM 5901 O O . CYS B 1 348 ? 59.159 38.305 31.970 1.00 23.54 ? 538 CYS B O 1 ATOM 5902 C CB . CYS B 1 348 ? 56.260 37.789 30.688 1.00 23.41 ? 538 CYS B CB 1 ATOM 5903 S SG . CYS B 1 348 ? 56.517 37.160 29.002 1.00 24.58 ? 538 CYS B SG 1 ATOM 5904 N N . ARG B 1 349 ? 57.563 38.634 33.515 1.00 23.83 ? 539 ARG B N 1 ATOM 5905 C CA . ARG B 1 349 ? 58.362 39.619 34.226 1.00 22.53 ? 539 ARG B CA 1 ATOM 5906 C C . ARG B 1 349 ? 57.838 39.879 35.630 1.00 26.62 ? 539 ARG B C 1 ATOM 5907 O O . ARG B 1 349 ? 56.831 39.309 36.048 1.00 28.68 ? 539 ARG B O 1 ATOM 5908 C CB . ARG B 1 349 ? 58.371 40.928 33.435 1.00 23.01 ? 539 ARG B CB 1 ATOM 5909 C CG . ARG B 1 349 ? 57.059 41.701 33.494 1.00 17.81 ? 539 ARG B CG 1 ATOM 5910 C CD . ARG B 1 349 ? 57.005 42.771 32.420 1.00 23.21 ? 539 ARG B CD 1 ATOM 5911 N NE . ARG B 1 349 ? 56.742 42.189 31.108 1.00 29.98 ? 539 ARG B NE 1 ATOM 5912 C CZ . ARG B 1 349 ? 55.547 41.763 30.710 1.00 33.40 ? 539 ARG B CZ 1 ATOM 5913 N NH1 . ARG B 1 349 ? 54.505 41.863 31.526 1.00 33.58 ? 539 ARG B NH1 1 ATOM 5914 N NH2 . ARG B 1 349 ? 55.398 41.217 29.508 1.00 25.89 ? 539 ARG B NH2 1 ATOM 5915 N N . LYS B 1 350 ? 58.533 40.755 36.348 1.00 30.04 ? 540 LYS B N 1 ATOM 5916 C CA . LYS B 1 350 ? 58.159 41.120 37.706 1.00 34.79 ? 540 LYS B CA 1 ATOM 5917 C C . LYS B 1 350 ? 57.679 42.565 37.756 1.00 37.67 ? 540 LYS B C 1 ATOM 5918 O O . LYS B 1 350 ? 58.141 43.411 36.993 1.00 35.31 ? 540 LYS B O 1 ATOM 5919 C CB . LYS B 1 350 ? 59.358 40.971 38.644 1.00 37.00 ? 540 LYS B CB 1 ATOM 5920 C CG . LYS B 1 350 ? 59.909 39.564 38.768 1.00 34.61 ? 540 LYS B CG 1 ATOM 5921 C CD . LYS B 1 350 ? 58.906 38.633 39.413 1.00 32.65 ? 540 LYS B CD 1 ATOM 5922 C CE . LYS B 1 350 ? 59.560 37.313 39.772 1.00 32.62 ? 540 LYS B CE 1 ATOM 5923 N NZ . LYS B 1 350 ? 60.620 37.502 40.794 1.00 18.64 ? 540 LYS B NZ 1 ATOM 5924 N N . GLU B 1 351 ? 56.748 42.834 38.664 1.00 44.23 ? 541 GLU B N 1 ATOM 5925 C CA . GLU B 1 351 ? 56.200 44.173 38.859 1.00 48.73 ? 541 GLU B CA 1 ATOM 5926 C C . GLU B 1 351 ? 55.733 44.288 40.303 1.00 52.21 ? 541 GLU B C 1 ATOM 5927 O O . GLU B 1 351 ? 54.713 43.710 40.684 1.00 51.99 ? 541 GLU B O 1 ATOM 5928 C CB . GLU B 1 351 ? 55.036 44.429 37.896 1.00 49.35 ? 541 GLU B CB 1 ATOM 5929 C CG . GLU B 1 351 ? 55.482 44.762 36.476 1.00 58.83 ? 541 GLU B CG 1 ATOM 5930 C CD . GLU B 1 351 ? 54.323 44.982 35.519 1.00 61.39 ? 541 GLU B CD 1 ATOM 5931 O OE1 . GLU B 1 351 ? 53.425 45.791 35.843 1.00 61.61 ? 541 GLU B OE1 1 ATOM 5932 O OE2 . GLU B 1 351 ? 54.315 44.352 34.437 1.00 62.35 ? 541 GLU B OE2 1 ATOM 5933 N N . ASN B 1 352 ? 56.495 45.031 41.104 1.00 54.96 ? 542 ASN B N 1 ATOM 5934 C CA . ASN B 1 352 ? 56.189 45.216 42.520 1.00 56.71 ? 542 ASN B CA 1 ATOM 5935 C C . ASN B 1 352 ? 56.413 43.886 43.231 1.00 56.89 ? 542 ASN B C 1 ATOM 5936 O O . ASN B 1 352 ? 55.905 43.660 44.331 1.00 59.44 ? 542 ASN B O 1 ATOM 5937 C CB . ASN B 1 352 ? 54.735 45.663 42.706 1.00 60.41 ? 542 ASN B CB 1 ATOM 5938 C CG . ASN B 1 352 ? 54.432 46.982 42.013 1.00 64.25 ? 542 ASN B CG 1 ATOM 5939 O OD1 . ASN B 1 352 ? 53.283 47.431 41.984 1.00 67.76 ? 542 ASN B OD1 1 ATOM 5940 N ND2 . ASN B 1 352 ? 55.463 47.611 41.453 1.00 58.73 ? 542 ASN B ND2 1 ATOM 5941 N N . GLY B 1 353 ? 57.181 43.010 42.588 1.00 52.19 ? 543 GLY B N 1 ATOM 5942 C CA . GLY B 1 353 ? 57.461 41.706 43.157 1.00 47.43 ? 543 GLY B CA 1 ATOM 5943 C C . GLY B 1 353 ? 56.549 40.640 42.579 1.00 45.73 ? 543 GLY B C 1 ATOM 5944 O O . GLY B 1 353 ? 56.898 39.457 42.546 1.00 42.18 ? 543 GLY B O 1 ATOM 5945 N N . ASN B 1 354 ? 55.374 41.063 42.122 1.00 41.46 ? 544 ASN B N 1 ATOM 5946 C CA . ASN B 1 354 ? 54.402 40.146 41.539 1.00 38.64 ? 544 ASN B CA 1 ATOM 5947 C C . ASN B 1 354 ? 54.866 39.712 40.156 1.00 35.18 ? 544 ASN B C 1 ATOM 5948 O O . ASN B 1 354 ? 55.401 40.518 39.389 1.00 32.39 ? 544 ASN B O 1 ATOM 5949 C CB . ASN B 1 354 ? 53.038 40.829 41.435 1.00 42.98 ? 544 ASN B CB 1 ATOM 5950 C CG . ASN B 1 354 ? 52.548 41.357 42.768 1.00 44.08 ? 544 ASN B CG 1 ATOM 5951 O OD1 . ASN B 1 354 ? 51.539 42.055 42.836 1.00 48.64 ? 544 ASN B OD1 1 ATOM 5952 N ND2 . ASN B 1 354 ? 53.260 41.023 43.839 1.00 49.14 ? 544 ASN B ND2 1 ATOM 5953 N N . LYS B 1 355 ? 54.667 38.437 39.841 1.00 29.26 ? 545 LYS B N 1 ATOM 5954 C CA . LYS B 1 355 ? 55.076 37.920 38.543 1.00 29.53 ? 545 LYS B CA 1 ATOM 5955 C C . LYS B 1 355 ? 53.913 37.907 37.556 1.00 26.96 ? 545 LYS B C 1 ATOM 5956 O O . LYS B 1 355 ? 52.889 37.260 37.783 1.00 23.25 ? 545 LYS B O 1 ATOM 5957 C CB . LYS B 1 355 ? 55.689 36.524 38.699 1.00 27.67 ? 545 LYS B CB 1 ATOM 5958 C CG . LYS B 1 355 ? 54.913 35.591 39.604 1.00 31.91 ? 545 LYS B CG 1 ATOM 5959 C CD . LYS B 1 355 ? 55.694 34.313 39.885 1.00 32.20 ? 545 LYS B CD 1 ATOM 5960 C CE . LYS B 1 355 ? 57.000 34.598 40.621 1.00 32.01 ? 545 LYS B CE 1 ATOM 5961 N NZ . LYS B 1 355 ? 57.707 33.344 41.015 1.00 26.13 ? 545 LYS B NZ 1 ATOM 5962 N N . ILE B 1 356 ? 54.092 38.642 36.461 1.00 23.20 ? 546 ILE B N 1 ATOM 5963 C CA . ILE B 1 356 ? 53.085 38.772 35.416 1.00 19.32 ? 546 ILE B CA 1 ATOM 5964 C C . ILE B 1 356 ? 53.199 37.675 34.366 1.00 18.49 ? 546 ILE B C 1 ATOM 5965 O O . ILE B 1 356 ? 54.296 37.336 33.927 1.00 20.57 ? 546 ILE B O 1 ATOM 5966 C CB . ILE B 1 356 ? 53.222 40.126 34.696 1.00 22.19 ? 546 ILE B CB 1 ATOM 5967 C CG1 . ILE B 1 356 ? 53.551 41.225 35.710 1.00 19.38 ? 546 ILE B CG1 1 ATOM 5968 C CG2 . ILE B 1 356 ? 51.934 40.455 33.957 1.00 21.40 ? 546 ILE B CG2 1 ATOM 5969 C CD1 . ILE B 1 356 ? 52.548 41.352 36.835 1.00 20.39 ? 546 ILE B CD1 1 ATOM 5970 N N . PRO B 1 357 ? 52.059 37.112 33.937 1.00 18.89 ? 547 PRO B N 1 ATOM 5971 C CA . PRO B 1 357 ? 52.067 36.051 32.927 1.00 17.28 ? 547 PRO B CA 1 ATOM 5972 C C . PRO B 1 357 ? 52.389 36.602 31.541 1.00 19.46 ? 547 PRO B C 1 ATOM 5973 O O . PRO B 1 357 ? 52.118 37.765 31.254 1.00 25.09 ? 547 PRO B O 1 ATOM 5974 C CB . PRO B 1 357 ? 50.649 35.499 33.010 1.00 12.22 ? 547 PRO B CB 1 ATOM 5975 C CG . PRO B 1 357 ? 49.852 36.726 33.296 1.00 11.99 ? 547 PRO B CG 1 ATOM 5976 C CD . PRO B 1 357 ? 50.679 37.413 34.364 1.00 16.50 ? 547 PRO B CD 1 ATOM 5977 N N . CYS B 1 358 ? 52.980 35.772 30.689 1.00 19.12 ? 548 CYS B N 1 ATOM 5978 C CA . CYS B 1 358 ? 53.304 36.201 29.337 1.00 16.99 ? 548 CYS B CA 1 ATOM 5979 C C . CYS B 1 358 ? 52.036 36.279 28.515 1.00 17.29 ? 548 CYS B C 1 ATOM 5980 O O . CYS B 1 358 ? 51.096 35.512 28.731 1.00 14.30 ? 548 CYS B O 1 ATOM 5981 C CB . CYS B 1 358 ? 54.229 35.209 28.639 1.00 19.10 ? 548 CYS B CB 1 ATOM 5982 S SG . CYS B 1 358 ? 55.973 35.214 29.140 1.00 23.75 ? 548 CYS B SG 1 ATOM 5983 N N . ALA B 1 359 ? 52.015 37.210 27.570 1.00 19.01 ? 549 ALA B N 1 ATOM 5984 C CA . ALA B 1 359 ? 50.881 37.349 26.672 1.00 17.53 ? 549 ALA B CA 1 ATOM 5985 C C . ALA B 1 359 ? 51.162 36.303 25.597 1.00 14.70 ? 549 ALA B C 1 ATOM 5986 O O . ALA B 1 359 ? 52.314 35.929 25.378 1.00 10.63 ? 549 ALA B O 1 ATOM 5987 C CB . ALA B 1 359 ? 50.848 38.749 26.066 1.00 12.03 ? 549 ALA B CB 1 ATOM 5988 N N . PRO B 1 360 ? 50.119 35.812 24.915 1.00 19.68 ? 550 PRO B N 1 ATOM 5989 C CA . PRO B 1 360 ? 50.308 34.801 23.869 1.00 22.13 ? 550 PRO B CA 1 ATOM 5990 C C . PRO B 1 360 ? 51.483 35.052 22.917 1.00 22.16 ? 550 PRO B C 1 ATOM 5991 O O . PRO B 1 360 ? 52.129 34.110 22.467 1.00 20.36 ? 550 PRO B O 1 ATOM 5992 C CB . PRO B 1 360 ? 48.965 34.807 23.151 1.00 16.27 ? 550 PRO B CB 1 ATOM 5993 C CG . PRO B 1 360 ? 48.013 35.056 24.276 1.00 18.60 ? 550 PRO B CG 1 ATOM 5994 C CD . PRO B 1 360 ? 48.695 36.171 25.046 1.00 16.89 ? 550 PRO B CD 1 ATOM 5995 N N . GLU B 1 361 ? 51.765 36.319 22.628 1.00 26.94 ? 551 GLU B N 1 ATOM 5996 C CA . GLU B 1 361 ? 52.846 36.677 21.713 1.00 27.71 ? 551 GLU B CA 1 ATOM 5997 C C . GLU B 1 361 ? 54.209 36.879 22.372 1.00 29.05 ? 551 GLU B C 1 ATOM 5998 O O . GLU B 1 361 ? 55.223 36.952 21.680 1.00 32.80 ? 551 GLU B O 1 ATOM 5999 C CB . GLU B 1 361 ? 52.490 37.954 20.947 1.00 29.77 ? 551 GLU B CB 1 ATOM 6000 C CG . GLU B 1 361 ? 51.047 38.037 20.483 1.00 42.86 ? 551 GLU B CG 1 ATOM 6001 C CD . GLU B 1 361 ? 50.106 38.471 21.592 1.00 48.89 ? 551 GLU B CD 1 ATOM 6002 O OE1 . GLU B 1 361 ? 48.874 38.463 21.373 1.00 52.77 ? 551 GLU B OE1 1 ATOM 6003 O OE2 . GLU B 1 361 ? 50.602 38.827 22.683 1.00 49.36 ? 551 GLU B OE2 1 ATOM 6004 N N . ASP B 1 362 ? 54.241 36.976 23.697 1.00 28.28 ? 552 ASP B N 1 ATOM 6005 C CA . ASP B 1 362 ? 55.501 37.188 24.409 1.00 27.23 ? 552 ASP B CA 1 ATOM 6006 C C . ASP B 1 362 ? 55.956 35.921 25.117 1.00 24.27 ? 552 ASP B C 1 ATOM 6007 O O . ASP B 1 362 ? 56.862 35.947 25.950 1.00 22.44 ? 552 ASP B O 1 ATOM 6008 C CB . ASP B 1 362 ? 55.335 38.307 25.437 1.00 26.20 ? 552 ASP B CB 1 ATOM 6009 C CG . ASP B 1 362 ? 54.852 39.601 24.816 1.00 32.63 ? 552 ASP B CG 1 ATOM 6010 O OD1 . ASP B 1 362 ? 55.522 40.097 23.883 1.00 35.15 ? 552 ASP B OD1 1 ATOM 6011 O OD2 . ASP B 1 362 ? 53.806 40.124 25.262 1.00 31.50 ? 552 ASP B OD2 1 ATOM 6012 N N . VAL B 1 363 ? 55.323 34.812 24.760 1.00 23.32 ? 553 VAL B N 1 ATOM 6013 C CA . VAL B 1 363 ? 55.598 33.515 25.361 1.00 22.10 ? 553 VAL B CA 1 ATOM 6014 C C . VAL B 1 363 ? 57.054 33.028 25.293 1.00 22.20 ? 553 VAL B C 1 ATOM 6015 O O . VAL B 1 363 ? 57.491 32.256 26.145 1.00 23.92 ? 553 VAL B O 1 ATOM 6016 C CB . VAL B 1 363 ? 54.666 32.453 24.739 1.00 16.28 ? 553 VAL B CB 1 ATOM 6017 C CG1 . VAL B 1 363 ? 55.401 31.650 23.679 1.00 15.55 ? 553 VAL B CG1 1 ATOM 6018 C CG2 . VAL B 1 363 ? 54.105 31.574 25.820 1.00 18.90 ? 553 VAL B CG2 1 ATOM 6019 N N . LYS B 1 364 ? 57.798 33.472 24.285 1.00 21.35 ? 554 LYS B N 1 ATOM 6020 C CA . LYS B 1 364 ? 59.192 33.064 24.130 1.00 22.21 ? 554 LYS B CA 1 ATOM 6021 C C . LYS B 1 364 ? 60.141 33.952 24.931 1.00 22.85 ? 554 LYS B C 1 ATOM 6022 O O . LYS B 1 364 ? 61.360 33.836 24.804 1.00 26.78 ? 554 LYS B O 1 ATOM 6023 C CB . LYS B 1 364 ? 59.608 33.117 22.656 1.00 24.80 ? 554 LYS B CB 1 ATOM 6024 C CG . LYS B 1 364 ? 59.032 32.032 21.763 1.00 25.65 ? 554 LYS B CG 1 ATOM 6025 C CD . LYS B 1 364 ? 59.600 30.673 22.109 1.00 32.54 ? 554 LYS B CD 1 ATOM 6026 C CE . LYS B 1 364 ? 59.629 29.766 20.888 1.00 37.92 ? 554 LYS B CE 1 ATOM 6027 N NZ . LYS B 1 364 ? 58.308 29.678 20.214 1.00 38.95 ? 554 LYS B NZ 1 ATOM 6028 N N . CYS B 1 365 ? 59.590 34.836 25.754 1.00 21.42 ? 555 CYS B N 1 ATOM 6029 C CA . CYS B 1 365 ? 60.423 35.735 26.539 1.00 20.61 ? 555 CYS B CA 1 ATOM 6030 C C . CYS B 1 365 ? 60.277 35.564 28.038 1.00 20.80 ? 555 CYS B C 1 ATOM 6031 O O . CYS B 1 365 ? 60.692 36.434 28.807 1.00 23.02 ? 555 CYS B O 1 ATOM 6032 C CB . CYS B 1 365 ? 60.127 37.186 26.168 1.00 20.10 ? 555 CYS B CB 1 ATOM 6033 S SG . CYS B 1 365 ? 60.601 37.611 24.465 1.00 29.77 ? 555 CYS B SG 1 ATOM 6034 N N . GLY B 1 366 ? 59.683 34.451 28.454 1.00 17.57 ? 556 GLY B N 1 ATOM 6035 C CA . GLY B 1 366 ? 59.517 34.196 29.872 1.00 17.78 ? 556 GLY B CA 1 ATOM 6036 C C . GLY B 1 366 ? 60.461 33.090 30.307 1.00 22.32 ? 556 GLY B C 1 ATOM 6037 O O . GLY B 1 366 ? 61.648 33.099 29.961 1.00 19.92 ? 556 GLY B O 1 ATOM 6038 N N . ARG B 1 367 ? 59.941 32.134 31.069 1.00 18.59 ? 557 ARG B N 1 ATOM 6039 C CA . ARG B 1 367 ? 60.758 31.019 31.518 1.00 15.78 ? 557 ARG B CA 1 ATOM 6040 C C . ARG B 1 367 ? 61.209 30.274 30.276 1.00 13.75 ? 557 ARG B C 1 ATOM 6041 O O . ARG B 1 367 ? 60.444 30.140 29.325 1.00 14.17 ? 557 ARG B O 1 ATOM 6042 C CB . ARG B 1 367 ? 59.942 30.076 32.401 1.00 17.73 ? 557 ARG B CB 1 ATOM 6043 C CG . ARG B 1 367 ? 60.738 28.921 32.987 1.00 7.46 ? 557 ARG B CG 1 ATOM 6044 C CD . ARG B 1 367 ? 61.754 29.411 34.007 1.00 11.63 ? 557 ARG B CD 1 ATOM 6045 N NE . ARG B 1 367 ? 61.131 30.280 35.002 1.00 6.48 ? 557 ARG B NE 1 ATOM 6046 C CZ . ARG B 1 367 ? 61.764 30.796 36.049 1.00 3.19 ? 557 ARG B CZ 1 ATOM 6047 N NH1 . ARG B 1 367 ? 63.045 30.529 36.249 1.00 5.18 ? 557 ARG B NH1 1 ATOM 6048 N NH2 . ARG B 1 367 ? 61.116 31.586 36.894 1.00 9.50 ? 557 ARG B NH2 1 ATOM 6049 N N . LEU B 1 368 ? 62.449 29.802 30.282 1.00 17.03 ? 558 LEU B N 1 ATOM 6050 C CA . LEU B 1 368 ? 62.989 29.056 29.150 1.00 17.49 ? 558 LEU B CA 1 ATOM 6051 C C . LEU B 1 368 ? 62.655 27.570 29.274 1.00 16.13 ? 558 LEU B C 1 ATOM 6052 O O . LEU B 1 368 ? 62.551 27.038 30.378 1.00 18.44 ? 558 LEU B O 1 ATOM 6053 C CB . LEU B 1 368 ? 64.508 29.240 29.078 1.00 10.28 ? 558 LEU B CB 1 ATOM 6054 C CG . LEU B 1 368 ? 65.277 28.280 28.162 1.00 16.86 ? 558 LEU B CG 1 ATOM 6055 C CD1 . LEU B 1 368 ? 64.745 28.375 26.737 1.00 15.69 ? 558 LEU B CD1 1 ATOM 6056 C CD2 . LEU B 1 368 ? 66.769 28.613 28.208 1.00 12.08 ? 558 LEU B CD2 1 ATOM 6057 N N . TYR B 1 369 ? 62.474 26.910 28.136 1.00 18.77 ? 559 TYR B N 1 ATOM 6058 C CA . TYR B 1 369 ? 62.168 25.483 28.111 1.00 17.56 ? 559 TYR B CA 1 ATOM 6059 C C . TYR B 1 369 ? 63.064 24.799 27.091 1.00 21.97 ? 559 TYR B C 1 ATOM 6060 O O . TYR B 1 369 ? 63.300 25.331 26.005 1.00 21.62 ? 559 TYR B O 1 ATOM 6061 C CB . TYR B 1 369 ? 60.702 25.251 27.750 1.00 14.07 ? 559 TYR B CB 1 ATOM 6062 C CG . TYR B 1 369 ? 59.743 25.907 28.709 1.00 17.74 ? 559 TYR B CG 1 ATOM 6063 C CD1 . TYR B 1 369 ? 59.427 27.258 28.593 1.00 20.13 ? 559 TYR B CD1 1 ATOM 6064 C CD2 . TYR B 1 369 ? 59.189 25.192 29.767 1.00 13.25 ? 559 TYR B CD2 1 ATOM 6065 C CE1 . TYR B 1 369 ? 58.588 27.882 29.506 1.00 15.54 ? 559 TYR B CE1 1 ATOM 6066 C CE2 . TYR B 1 369 ? 58.351 25.806 30.684 1.00 17.21 ? 559 TYR B CE2 1 ATOM 6067 C CZ . TYR B 1 369 ? 58.055 27.153 30.547 1.00 14.83 ? 559 TYR B CZ 1 ATOM 6068 O OH . TYR B 1 369 ? 57.222 27.767 31.452 1.00 17.36 ? 559 TYR B OH 1 ATOM 6069 N N . CYS B 1 370 ? 63.565 23.620 27.439 1.00 22.30 ? 560 CYS B N 1 ATOM 6070 C CA . CYS B 1 370 ? 64.446 22.894 26.542 1.00 27.36 ? 560 CYS B CA 1 ATOM 6071 C C . CYS B 1 370 ? 64.038 21.427 26.439 1.00 30.92 ? 560 CYS B C 1 ATOM 6072 O O . CYS B 1 370 ? 63.337 20.911 27.306 1.00 31.13 ? 560 CYS B O 1 ATOM 6073 C CB . CYS B 1 370 ? 65.886 23.009 27.044 1.00 25.82 ? 560 CYS B CB 1 ATOM 6074 S SG . CYS B 1 370 ? 66.364 24.697 27.552 1.00 23.69 ? 560 CYS B SG 1 ATOM 6075 N N . LYS B 1 371 ? 64.475 20.766 25.369 1.00 36.51 ? 561 LYS B N 1 ATOM 6076 C CA . LYS B 1 371 ? 64.165 19.357 25.144 1.00 37.50 ? 561 LYS B CA 1 ATOM 6077 C C . LYS B 1 371 ? 65.406 18.494 25.359 1.00 40.51 ? 561 LYS B C 1 ATOM 6078 O O . LYS B 1 371 ? 66.497 18.828 24.890 1.00 36.99 ? 561 LYS B O 1 ATOM 6079 C CB . LYS B 1 371 ? 63.643 19.142 23.720 1.00 40.46 ? 561 LYS B CB 1 ATOM 6080 C CG . LYS B 1 371 ? 64.644 19.503 22.630 1.00 43.73 ? 561 LYS B CG 1 ATOM 6081 C CD . LYS B 1 371 ? 64.379 18.729 21.341 1.00 45.86 ? 561 LYS B CD 1 ATOM 6082 C CE . LYS B 1 371 ? 63.069 19.132 20.684 1.00 46.05 ? 561 LYS B CE 1 ATOM 6083 N NZ . LYS B 1 371 ? 63.121 20.526 20.172 1.00 47.96 ? 561 LYS B NZ 1 ATOM 6084 N N . ASP B 1 372 ? 65.234 17.380 26.061 1.00 44.06 ? 562 ASP B N 1 ATOM 6085 C CA . ASP B 1 372 ? 66.344 16.477 26.339 1.00 49.34 ? 562 ASP B CA 1 ATOM 6086 C C . ASP B 1 372 ? 66.268 15.234 25.454 1.00 49.81 ? 562 ASP B C 1 ATOM 6087 O O . ASP B 1 372 ? 65.483 14.325 25.721 1.00 49.40 ? 562 ASP B O 1 ATOM 6088 C CB . ASP B 1 372 ? 66.320 16.066 27.813 1.00 53.72 ? 562 ASP B CB 1 ATOM 6089 C CG . ASP B 1 372 ? 67.625 15.444 28.266 1.00 57.61 ? 562 ASP B CG 1 ATOM 6090 O OD1 . ASP B 1 372 ? 67.690 14.975 29.423 1.00 60.41 ? 562 ASP B OD1 1 ATOM 6091 O OD2 . ASP B 1 372 ? 68.587 15.431 27.469 1.00 56.74 ? 562 ASP B OD2 1 ATOM 6092 N N . ASN B 1 373 ? 67.086 15.196 24.406 1.00 49.39 ? 563 ASN B N 1 ATOM 6093 C CA . ASN B 1 373 ? 67.094 14.059 23.488 1.00 53.00 ? 563 ASN B CA 1 ATOM 6094 C C . ASN B 1 373 ? 67.994 12.923 23.962 1.00 52.41 ? 563 ASN B C 1 ATOM 6095 O O . ASN B 1 373 ? 68.842 12.438 23.213 1.00 52.79 ? 563 ASN B O 1 ATOM 6096 C CB . ASN B 1 373 ? 67.527 14.508 22.087 1.00 58.94 ? 563 ASN B CB 1 ATOM 6097 C CG . ASN B 1 373 ? 66.483 15.374 21.399 1.00 64.10 ? 563 ASN B CG 1 ATOM 6098 O OD1 . ASN B 1 373 ? 66.670 15.807 20.261 1.00 61.37 ? 563 ASN B OD1 1 ATOM 6099 N ND2 . ASN B 1 373 ? 65.375 15.629 22.089 1.00 67.67 ? 563 ASN B ND2 1 ATOM 6100 N N . SER B 1 374 ? 67.799 12.499 25.207 1.00 50.63 ? 564 SER B N 1 ATOM 6101 C CA . SER B 1 374 ? 68.586 11.415 25.787 1.00 46.04 ? 564 SER B CA 1 ATOM 6102 C C . SER B 1 374 ? 67.768 10.130 25.764 1.00 45.16 ? 564 SER B C 1 ATOM 6103 O O . SER B 1 374 ? 66.570 10.146 26.049 1.00 48.62 ? 564 SER B O 1 ATOM 6104 C CB . SER B 1 374 ? 68.948 11.740 27.236 1.00 44.44 ? 564 SER B CB 1 ATOM 6105 O OG . SER B 1 374 ? 69.551 13.015 27.345 1.00 53.80 ? 564 SER B OG 1 ATOM 6106 N N . PRO B 1 375 ? 68.402 8.997 25.427 1.00 40.42 ? 565 PRO B N 1 ATOM 6107 C CA . PRO B 1 375 ? 67.666 7.732 25.394 1.00 39.51 ? 565 PRO B CA 1 ATOM 6108 C C . PRO B 1 375 ? 66.995 7.465 26.739 1.00 42.23 ? 565 PRO B C 1 ATOM 6109 O O . PRO B 1 375 ? 67.606 7.658 27.791 1.00 41.45 ? 565 PRO B O 1 ATOM 6110 C CB . PRO B 1 375 ? 68.752 6.711 25.069 1.00 35.35 ? 565 PRO B CB 1 ATOM 6111 C CG . PRO B 1 375 ? 69.985 7.333 25.646 1.00 37.24 ? 565 PRO B CG 1 ATOM 6112 C CD . PRO B 1 375 ? 69.841 8.769 25.223 1.00 36.99 ? 565 PRO B CD 1 ATOM 6113 N N . GLY B 1 376 ? 65.735 7.037 26.699 1.00 43.09 ? 566 GLY B N 1 ATOM 6114 C CA . GLY B 1 376 ? 65.011 6.762 27.927 1.00 44.56 ? 566 GLY B CA 1 ATOM 6115 C C . GLY B 1 376 ? 64.380 8.013 28.508 1.00 47.94 ? 566 GLY B C 1 ATOM 6116 O O . GLY B 1 376 ? 63.171 8.212 28.390 1.00 49.51 ? 566 GLY B O 1 ATOM 6117 N N . GLN B 1 377 ? 65.195 8.855 29.142 1.00 51.04 ? 567 GLN B N 1 ATOM 6118 C CA . GLN B 1 377 ? 64.702 10.097 29.728 1.00 52.82 ? 567 GLN B CA 1 ATOM 6119 C C . GLN B 1 377 ? 64.012 10.925 28.652 1.00 54.66 ? 567 GLN B C 1 ATOM 6120 O O . GLN B 1 377 ? 64.657 11.405 27.719 1.00 50.78 ? 567 GLN B O 1 ATOM 6121 C CB . GLN B 1 377 ? 65.849 10.916 30.336 1.00 55.13 ? 567 GLN B CB 1 ATOM 6122 C CG . GLN B 1 377 ? 66.313 10.465 31.723 1.00 57.16 ? 567 GLN B CG 1 ATOM 6123 C CD . GLN B 1 377 ? 67.113 9.175 31.699 1.00 57.54 ? 567 GLN B CD 1 ATOM 6124 O OE1 . GLN B 1 377 ? 66.611 8.122 31.301 1.00 55.09 ? 567 GLN B OE1 1 ATOM 6125 N NE2 . GLN B 1 377 ? 68.369 9.252 32.128 1.00 57.66 ? 567 GLN B NE2 1 ATOM 6126 N N . ASN B 1 378 ? 62.699 11.087 28.790 1.00 56.94 ? 568 ASN B N 1 ATOM 6127 C CA . ASN B 1 378 ? 61.917 11.851 27.828 1.00 57.14 ? 568 ASN B CA 1 ATOM 6128 C C . ASN B 1 378 ? 61.114 12.987 28.456 1.00 53.40 ? 568 ASN B C 1 ATOM 6129 O O . ASN B 1 378 ? 59.946 12.812 28.806 1.00 51.87 ? 568 ASN B O 1 ATOM 6130 C CB . ASN B 1 378 ? 60.969 10.921 27.063 1.00 62.86 ? 568 ASN B CB 1 ATOM 6131 C CG . ASN B 1 378 ? 59.869 11.678 26.329 1.00 66.50 ? 568 ASN B CG 1 ATOM 6132 O OD1 . ASN B 1 378 ? 60.136 12.629 25.594 1.00 67.74 ? 568 ASN B OD1 1 ATOM 6133 N ND2 . ASN B 1 378 ? 58.625 11.254 26.527 1.00 67.75 ? 568 ASN B ND2 1 ATOM 6134 N N . ASN B 1 379 ? 61.748 14.147 28.605 1.00 49.41 ? 569 ASN B N 1 ATOM 6135 C CA . ASN B 1 379 ? 61.074 15.321 29.151 1.00 46.38 ? 569 ASN B CA 1 ATOM 6136 C C . ASN B 1 379 ? 61.087 16.375 28.049 1.00 42.79 ? 569 ASN B C 1 ATOM 6137 O O . ASN B 1 379 ? 62.119 16.992 27.777 1.00 43.60 ? 569 ASN B O 1 ATOM 6138 C CB . ASN B 1 379 ? 61.800 15.864 30.384 1.00 44.58 ? 569 ASN B CB 1 ATOM 6139 C CG . ASN B 1 379 ? 60.988 16.923 31.117 1.00 43.33 ? 569 ASN B CG 1 ATOM 6140 O OD1 . ASN B 1 379 ? 60.405 17.815 30.497 1.00 37.63 ? 569 ASN B OD1 1 ATOM 6141 N ND2 . ASN B 1 379 ? 60.953 16.832 32.442 1.00 44.93 ? 569 ASN B ND2 1 ATOM 6142 N N . PRO B 1 380 ? 59.936 16.590 27.398 1.00 38.21 ? 570 PRO B N 1 ATOM 6143 C CA . PRO B 1 380 ? 59.804 17.566 26.314 1.00 38.31 ? 570 PRO B CA 1 ATOM 6144 C C . PRO B 1 380 ? 59.964 19.038 26.714 1.00 37.69 ? 570 PRO B C 1 ATOM 6145 O O . PRO B 1 380 ? 60.426 19.852 25.912 1.00 37.10 ? 570 PRO B O 1 ATOM 6146 C CB . PRO B 1 380 ? 58.418 17.261 25.754 1.00 35.81 ? 570 PRO B CB 1 ATOM 6147 C CG . PRO B 1 380 ? 57.663 16.840 26.976 1.00 37.62 ? 570 PRO B CG 1 ATOM 6148 C CD . PRO B 1 380 ? 58.647 15.928 27.668 1.00 36.38 ? 570 PRO B CD 1 ATOM 6149 N N . CYS B 1 381 ? 59.591 19.381 27.944 1.00 34.11 ? 571 CYS B N 1 ATOM 6150 C CA . CYS B 1 381 ? 59.700 20.764 28.391 1.00 33.51 ? 571 CYS B CA 1 ATOM 6151 C C . CYS B 1 381 ? 60.584 20.959 29.624 1.00 33.29 ? 571 CYS B C 1 ATOM 6152 O O . CYS B 1 381 ? 60.095 21.385 30.673 1.00 33.36 ? 571 CYS B O 1 ATOM 6153 C CB . CYS B 1 381 ? 58.315 21.338 28.695 1.00 30.53 ? 571 CYS B CB 1 ATOM 6154 S SG . CYS B 1 381 ? 57.054 21.184 27.387 1.00 36.72 ? 571 CYS B SG 1 ATOM 6155 N N . LYS B 1 382 ? 61.875 20.655 29.508 1.00 28.93 ? 572 LYS B N 1 ATOM 6156 C CA . LYS B 1 382 ? 62.774 20.841 30.642 1.00 27.51 ? 572 LYS B CA 1 ATOM 6157 C C . LYS B 1 382 ? 62.899 22.326 30.925 1.00 25.31 ? 572 LYS B C 1 ATOM 6158 O O . LYS B 1 382 ? 63.097 23.134 30.016 1.00 26.11 ? 572 LYS B O 1 ATOM 6159 C CB . LYS B 1 382 ? 64.167 20.264 30.368 1.00 30.83 ? 572 LYS B CB 1 ATOM 6160 C CG . LYS B 1 382 ? 64.221 18.746 30.320 1.00 41.79 ? 572 LYS B CG 1 ATOM 6161 C CD . LYS B 1 382 ? 65.641 18.236 30.517 1.00 45.24 ? 572 LYS B CD 1 ATOM 6162 C CE . LYS B 1 382 ? 66.127 18.496 31.936 1.00 46.30 ? 572 LYS B CE 1 ATOM 6163 N NZ . LYS B 1 382 ? 65.286 17.792 32.947 1.00 47.16 ? 572 LYS B NZ 1 ATOM 6164 N N . MET B 1 383 ? 62.786 22.677 32.195 1.00 21.49 ? 573 MET B N 1 ATOM 6165 C CA . MET B 1 383 ? 62.873 24.061 32.612 1.00 20.51 ? 573 MET B CA 1 ATOM 6166 C C . MET B 1 383 ? 63.638 24.137 33.924 1.00 20.29 ? 573 MET B C 1 ATOM 6167 O O . MET B 1 383 ? 63.724 23.154 34.652 1.00 21.82 ? 573 MET B O 1 ATOM 6168 C CB . MET B 1 383 ? 61.455 24.622 32.756 1.00 19.20 ? 573 MET B CB 1 ATOM 6169 C CG . MET B 1 383 ? 61.316 25.826 33.649 1.00 23.58 ? 573 MET B CG 1 ATOM 6170 S SD . MET B 1 383 ? 61.256 25.375 35.387 1.00 28.63 ? 573 MET B SD 1 ATOM 6171 C CE . MET B 1 383 ? 59.600 24.749 35.518 1.00 17.81 ? 573 MET B CE 1 ATOM 6172 N N . PHE B 1 384 ? 64.207 25.298 34.220 1.00 18.26 ? 574 PHE B N 1 ATOM 6173 C CA . PHE B 1 384 ? 64.950 25.458 35.457 1.00 19.09 ? 574 PHE B CA 1 ATOM 6174 C C . PHE B 1 384 ? 64.342 26.521 36.362 1.00 21.28 ? 574 PHE B C 1 ATOM 6175 O O . PHE B 1 384 ? 64.098 27.653 35.939 1.00 24.29 ? 574 PHE B O 1 ATOM 6176 C CB . PHE B 1 384 ? 66.410 25.802 35.159 1.00 22.90 ? 574 PHE B CB 1 ATOM 6177 C CG . PHE B 1 384 ? 67.260 25.947 36.389 1.00 26.66 ? 574 PHE B CG 1 ATOM 6178 C CD1 . PHE B 1 384 ? 67.243 27.125 37.131 1.00 29.78 ? 574 PHE B CD1 1 ATOM 6179 C CD2 . PHE B 1 384 ? 68.058 24.892 36.823 1.00 28.47 ? 574 PHE B CD2 1 ATOM 6180 C CE1 . PHE B 1 384 ? 68.007 27.251 38.288 1.00 29.93 ? 574 PHE B CE1 1 ATOM 6181 C CE2 . PHE B 1 384 ? 68.825 25.005 37.978 1.00 27.24 ? 574 PHE B CE2 1 ATOM 6182 C CZ . PHE B 1 384 ? 68.799 26.189 38.713 1.00 33.00 ? 574 PHE B CZ 1 ATOM 6183 N N . TYR B 1 385 ? 64.094 26.139 37.611 1.00 18.21 ? 575 TYR B N 1 ATOM 6184 C CA . TYR B 1 385 ? 63.537 27.044 38.604 1.00 13.62 ? 575 TYR B CA 1 ATOM 6185 C C . TYR B 1 385 ? 64.150 26.793 39.972 1.00 13.21 ? 575 TYR B C 1 ATOM 6186 O O . TYR B 1 385 ? 64.284 25.651 40.403 1.00 9.98 ? 575 TYR B O 1 ATOM 6187 C CB . TYR B 1 385 ? 62.018 26.885 38.729 1.00 15.94 ? 575 TYR B CB 1 ATOM 6188 C CG . TYR B 1 385 ? 61.461 27.738 39.851 1.00 10.41 ? 575 TYR B CG 1 ATOM 6189 C CD1 . TYR B 1 385 ? 61.242 29.099 39.672 1.00 6.36 ? 575 TYR B CD1 1 ATOM 6190 C CD2 . TYR B 1 385 ? 61.260 27.205 41.122 1.00 12.51 ? 575 TYR B CD2 1 ATOM 6191 C CE1 . TYR B 1 385 ? 60.844 29.910 40.729 1.00 17.74 ? 575 TYR B CE1 1 ATOM 6192 C CE2 . TYR B 1 385 ? 60.865 28.004 42.185 1.00 13.64 ? 575 TYR B CE2 1 ATOM 6193 C CZ . TYR B 1 385 ? 60.658 29.356 41.984 1.00 18.66 ? 575 TYR B CZ 1 ATOM 6194 O OH . TYR B 1 385 ? 60.269 30.154 43.038 1.00 19.97 ? 575 TYR B OH 1 ATOM 6195 N N . SER B 1 386 ? 64.498 27.877 40.656 1.00 16.85 ? 576 SER B N 1 ATOM 6196 C CA . SER B 1 386 ? 65.082 27.813 41.988 1.00 18.51 ? 576 SER B CA 1 ATOM 6197 C C . SER B 1 386 ? 64.742 29.117 42.692 1.00 22.24 ? 576 SER B C 1 ATOM 6198 O O . SER B 1 386 ? 65.044 30.196 42.183 1.00 21.94 ? 576 SER B O 1 ATOM 6199 C CB . SER B 1 386 ? 66.598 27.650 41.898 1.00 20.12 ? 576 SER B CB 1 ATOM 6200 O OG . SER B 1 386 ? 67.182 27.661 43.186 1.00 21.66 ? 576 SER B OG 1 ATOM 6201 N N . ASN B 1 387 ? 64.110 29.023 43.859 1.00 25.08 ? 577 ASN B N 1 ATOM 6202 C CA . ASN B 1 387 ? 63.727 30.221 44.594 1.00 22.22 ? 577 ASN B CA 1 ATOM 6203 C C . ASN B 1 387 ? 64.921 30.921 45.223 1.00 22.21 ? 577 ASN B C 1 ATOM 6204 O O . ASN B 1 387 ? 64.759 31.834 46.029 1.00 25.10 ? 577 ASN B O 1 ATOM 6205 C CB . ASN B 1 387 ? 62.681 29.886 45.660 1.00 19.61 ? 577 ASN B CB 1 ATOM 6206 C CG . ASN B 1 387 ? 63.249 29.095 46.807 1.00 13.40 ? 577 ASN B CG 1 ATOM 6207 O OD1 . ASN B 1 387 ? 64.217 28.358 46.646 1.00 26.57 ? 577 ASN B OD1 1 ATOM 6208 N ND2 . ASN B 1 387 ? 62.637 29.228 47.975 1.00 11.94 ? 577 ASN B ND2 1 ATOM 6209 N N . GLU B 1 388 ? 66.122 30.485 44.859 1.00 23.51 ? 578 GLU B N 1 ATOM 6210 C CA . GLU B 1 388 ? 67.336 31.116 45.360 1.00 26.69 ? 578 GLU B CA 1 ATOM 6211 C C . GLU B 1 388 ? 67.587 32.289 44.416 1.00 26.08 ? 578 GLU B C 1 ATOM 6212 O O . GLU B 1 388 ? 68.097 33.336 44.814 1.00 25.92 ? 578 GLU B O 1 ATOM 6213 C CB . GLU B 1 388 ? 68.517 30.137 45.318 1.00 29.05 ? 578 GLU B CB 1 ATOM 6214 C CG . GLU B 1 388 ? 69.808 30.697 45.917 1.00 36.63 ? 578 GLU B CG 1 ATOM 6215 C CD . GLU B 1 388 ? 70.925 29.663 46.032 1.00 39.58 ? 578 GLU B CD 1 ATOM 6216 O OE1 . GLU B 1 388 ? 72.047 30.050 46.418 1.00 40.79 ? 578 GLU B OE1 1 ATOM 6217 O OE2 . GLU B 1 388 ? 70.690 28.469 45.743 1.00 39.63 ? 578 GLU B OE2 1 ATOM 6218 N N . ASP B 1 389 ? 67.199 32.090 43.159 1.00 23.43 ? 579 ASP B N 1 ATOM 6219 C CA . ASP B 1 389 ? 67.333 33.089 42.109 1.00 21.95 ? 579 ASP B CA 1 ATOM 6220 C C . ASP B 1 389 ? 66.308 32.755 41.025 1.00 23.46 ? 579 ASP B C 1 ATOM 6221 O O . ASP B 1 389 ? 66.584 32.007 40.085 1.00 18.19 ? 579 ASP B O 1 ATOM 6222 C CB . ASP B 1 389 ? 68.749 33.067 41.531 1.00 27.55 ? 579 ASP B CB 1 ATOM 6223 C CG . ASP B 1 389 ? 68.979 34.170 40.517 1.00 36.26 ? 579 ASP B CG 1 ATOM 6224 O OD1 . ASP B 1 389 ? 68.618 35.329 40.812 1.00 40.74 ? 579 ASP B OD1 1 ATOM 6225 O OD2 . ASP B 1 389 ? 69.525 33.883 39.430 1.00 42.81 ? 579 ASP B OD2 1 ATOM 6226 N N . GLU B 1 390 ? 65.113 33.312 41.173 1.00 24.66 ? 580 GLU B N 1 ATOM 6227 C CA . GLU B 1 390 ? 64.032 33.060 40.234 1.00 20.88 ? 580 GLU B CA 1 ATOM 6228 C C . GLU B 1 390 ? 64.345 33.525 38.820 1.00 23.21 ? 580 GLU B C 1 ATOM 6229 O O . GLU B 1 390 ? 63.739 33.049 37.859 1.00 25.75 ? 580 GLU B O 1 ATOM 6230 C CB . GLU B 1 390 ? 62.746 33.718 40.738 1.00 14.91 ? 580 GLU B CB 1 ATOM 6231 C CG . GLU B 1 390 ? 62.366 33.293 42.152 1.00 21.30 ? 580 GLU B CG 1 ATOM 6232 C CD . GLU B 1 390 ? 61.007 33.815 42.587 1.00 26.94 ? 580 GLU B CD 1 ATOM 6233 O OE1 . GLU B 1 390 ? 60.803 35.046 42.555 1.00 29.06 ? 580 GLU B OE1 1 ATOM 6234 O OE2 . GLU B 1 390 ? 60.141 32.994 42.965 1.00 30.25 ? 580 GLU B OE2 1 ATOM 6235 N N . HIS B 1 391 ? 65.299 34.442 38.684 1.00 27.68 ? 581 HIS B N 1 ATOM 6236 C CA . HIS B 1 391 ? 65.657 34.950 37.364 1.00 26.08 ? 581 HIS B CA 1 ATOM 6237 C C . HIS B 1 391 ? 66.448 33.934 36.547 1.00 22.60 ? 581 HIS B C 1 ATOM 6238 O O . HIS B 1 391 ? 66.374 33.921 35.318 1.00 21.53 ? 581 HIS B O 1 ATOM 6239 C CB . HIS B 1 391 ? 66.455 36.249 37.474 1.00 27.27 ? 581 HIS B CB 1 ATOM 6240 C CG . HIS B 1 391 ? 66.755 36.876 36.149 1.00 33.03 ? 581 HIS B CG 1 ATOM 6241 N ND1 . HIS B 1 391 ? 65.766 37.313 35.294 1.00 31.62 ? 581 HIS B ND1 1 ATOM 6242 C CD2 . HIS B 1 391 ? 67.929 37.102 35.512 1.00 30.64 ? 581 HIS B CD2 1 ATOM 6243 C CE1 . HIS B 1 391 ? 66.317 37.779 34.187 1.00 25.71 ? 581 HIS B CE1 1 ATOM 6244 N NE2 . HIS B 1 391 ? 67.628 37.662 34.294 1.00 29.13 ? 581 HIS B NE2 1 ATOM 6245 N N . LYS B 1 392 ? 67.214 33.087 37.221 1.00 19.13 ? 582 LYS B N 1 ATOM 6246 C CA . LYS B 1 392 ? 67.976 32.074 36.508 1.00 19.25 ? 582 LYS B CA 1 ATOM 6247 C C . LYS B 1 392 ? 66.973 31.131 35.839 1.00 21.53 ? 582 LYS B C 1 ATOM 6248 O O . LYS B 1 392 ? 66.020 30.675 36.474 1.00 22.77 ? 582 LYS B O 1 ATOM 6249 C CB . LYS B 1 392 ? 68.877 31.301 37.478 1.00 13.88 ? 582 LYS B CB 1 ATOM 6250 C CG . LYS B 1 392 ? 69.748 30.255 36.804 1.00 18.69 ? 582 LYS B CG 1 ATOM 6251 C CD . LYS B 1 392 ? 70.685 29.564 37.786 1.00 21.62 ? 582 LYS B CD 1 ATOM 6252 C CE . LYS B 1 392 ? 71.512 28.492 37.084 1.00 28.44 ? 582 LYS B CE 1 ATOM 6253 N NZ . LYS B 1 392 ? 72.399 27.739 38.012 1.00 25.33 ? 582 LYS B NZ 1 ATOM 6254 N N . GLY B 1 393 ? 67.178 30.850 34.556 1.00 23.15 ? 583 GLY B N 1 ATOM 6255 C CA . GLY B 1 393 ? 66.267 29.971 33.840 1.00 20.17 ? 583 GLY B CA 1 ATOM 6256 C C . GLY B 1 393 ? 65.342 30.768 32.937 1.00 19.92 ? 583 GLY B C 1 ATOM 6257 O O . GLY B 1 393 ? 64.678 30.217 32.055 1.00 15.51 ? 583 GLY B O 1 ATOM 6258 N N . MET B 1 394 ? 65.296 32.075 33.173 1.00 18.28 ? 584 MET B N 1 ATOM 6259 C CA . MET B 1 394 ? 64.474 32.983 32.383 1.00 17.97 ? 584 MET B CA 1 ATOM 6260 C C . MET B 1 394 ? 65.232 33.347 31.112 1.00 19.82 ? 584 MET B C 1 ATOM 6261 O O . MET B 1 394 ? 66.444 33.557 31.148 1.00 21.05 ? 584 MET B O 1 ATOM 6262 C CB . MET B 1 394 ? 64.180 34.264 33.172 1.00 16.01 ? 584 MET B CB 1 ATOM 6263 C CG . MET B 1 394 ? 63.267 34.084 34.374 1.00 15.40 ? 584 MET B CG 1 ATOM 6264 S SD . MET B 1 394 ? 61.639 33.462 33.913 1.00 24.93 ? 584 MET B SD 1 ATOM 6265 C CE . MET B 1 394 ? 60.807 34.983 33.429 1.00 12.47 ? 584 MET B CE 1 ATOM 6266 N N . VAL B 1 395 ? 64.520 33.414 29.992 1.00 20.99 ? 585 VAL B N 1 ATOM 6267 C CA . VAL B 1 395 ? 65.140 33.769 28.722 1.00 18.78 ? 585 VAL B CA 1 ATOM 6268 C C . VAL B 1 395 ? 65.834 35.119 28.875 1.00 18.68 ? 585 VAL B C 1 ATOM 6269 O O . VAL B 1 395 ? 65.211 36.110 29.265 1.00 20.30 ? 585 VAL B O 1 ATOM 6270 C CB . VAL B 1 395 ? 64.088 33.858 27.595 1.00 17.88 ? 585 VAL B CB 1 ATOM 6271 C CG1 . VAL B 1 395 ? 64.729 34.353 26.313 1.00 18.33 ? 585 VAL B CG1 1 ATOM 6272 C CG2 . VAL B 1 395 ? 63.472 32.497 27.369 1.00 19.87 ? 585 VAL B CG2 1 ATOM 6273 N N . LEU B 1 396 ? 67.130 35.146 28.581 1.00 18.18 ? 586 LEU B N 1 ATOM 6274 C CA . LEU B 1 396 ? 67.922 36.366 28.691 1.00 18.47 ? 586 LEU B CA 1 ATOM 6275 C C . LEU B 1 396 ? 67.392 37.475 27.796 1.00 18.88 ? 586 LEU B C 1 ATOM 6276 O O . LEU B 1 396 ? 66.855 37.217 26.718 1.00 18.05 ? 586 LEU B O 1 ATOM 6277 C CB . LEU B 1 396 ? 69.381 36.093 28.313 1.00 12.66 ? 586 LEU B CB 1 ATOM 6278 C CG . LEU B 1 396 ? 70.278 35.307 29.270 1.00 13.36 ? 586 LEU B CG 1 ATOM 6279 C CD1 . LEU B 1 396 ? 71.581 34.952 28.551 1.00 9.52 ? 586 LEU B CD1 1 ATOM 6280 C CD2 . LEU B 1 396 ? 70.559 36.135 30.526 1.00 3.41 ? 586 LEU B CD2 1 ATOM 6281 N N . PRO B 1 397 ? 67.529 38.731 28.240 1.00 16.24 ? 587 PRO B N 1 ATOM 6282 C CA . PRO B 1 397 ? 67.055 39.856 27.433 1.00 17.13 ? 587 PRO B CA 1 ATOM 6283 C C . PRO B 1 397 ? 67.937 39.996 26.189 1.00 18.57 ? 587 PRO B C 1 ATOM 6284 O O . PRO B 1 397 ? 69.146 39.756 26.247 1.00 18.54 ? 587 PRO B O 1 ATOM 6285 C CB . PRO B 1 397 ? 67.186 41.040 28.388 1.00 16.84 ? 587 PRO B CB 1 ATOM 6286 C CG . PRO B 1 397 ? 68.334 40.645 29.264 1.00 12.90 ? 587 PRO B CG 1 ATOM 6287 C CD . PRO B 1 397 ? 68.043 39.193 29.541 1.00 12.71 ? 587 PRO B CD 1 ATOM 6288 N N . GLY B 1 398 ? 67.326 40.368 25.068 1.00 16.45 ? 588 GLY B N 1 ATOM 6289 C CA . GLY B 1 398 ? 68.069 40.515 23.829 1.00 15.21 ? 588 GLY B CA 1 ATOM 6290 C C . GLY B 1 398 ? 68.021 39.239 23.010 1.00 19.74 ? 588 GLY B C 1 ATOM 6291 O O . GLY B 1 398 ? 68.448 39.207 21.856 1.00 23.27 ? 588 GLY B O 1 ATOM 6292 N N . THR B 1 399 ? 67.499 38.177 23.612 1.00 19.07 ? 589 THR B N 1 ATOM 6293 C CA . THR B 1 399 ? 67.392 36.897 22.932 1.00 17.92 ? 589 THR B CA 1 ATOM 6294 C C . THR B 1 399 ? 66.405 36.988 21.770 1.00 19.27 ? 589 THR B C 1 ATOM 6295 O O . THR B 1 399 ? 65.333 37.581 21.892 1.00 17.89 ? 589 THR B O 1 ATOM 6296 C CB . THR B 1 399 ? 66.924 35.794 23.903 1.00 18.37 ? 589 THR B CB 1 ATOM 6297 O OG1 . THR B 1 399 ? 67.882 35.652 24.961 1.00 19.27 ? 589 THR B OG1 1 ATOM 6298 C CG2 . THR B 1 399 ? 66.763 34.463 23.171 1.00 2.69 ? 589 THR B CG2 1 ATOM 6299 N N . LYS B 1 400 ? 66.786 36.399 20.644 1.00 20.39 ? 590 LYS B N 1 ATOM 6300 C CA . LYS B 1 400 ? 65.961 36.397 19.445 1.00 20.29 ? 590 LYS B CA 1 ATOM 6301 C C . LYS B 1 400 ? 64.756 35.487 19.642 1.00 21.26 ? 590 LYS B C 1 ATOM 6302 O O . LYS B 1 400 ? 64.856 34.271 19.496 1.00 25.70 ? 590 LYS B O 1 ATOM 6303 C CB . LYS B 1 400 ? 66.791 35.917 18.247 1.00 16.71 ? 590 LYS B CB 1 ATOM 6304 C CG . LYS B 1 400 ? 66.020 35.871 16.949 1.00 16.91 ? 590 LYS B CG 1 ATOM 6305 C CD . LYS B 1 400 ? 66.903 35.458 15.799 1.00 14.31 ? 590 LYS B CD 1 ATOM 6306 C CE . LYS B 1 400 ? 66.138 35.500 14.486 1.00 15.98 ? 590 LYS B CE 1 ATOM 6307 N NZ . LYS B 1 400 ? 67.054 35.371 13.319 1.00 14.05 ? 590 LYS B NZ 1 ATOM 6308 N N . CYS B 1 401 ? 63.616 36.082 19.971 1.00 24.65 ? 591 CYS B N 1 ATOM 6309 C CA . CYS B 1 401 ? 62.390 35.322 20.204 1.00 24.20 ? 591 CYS B CA 1 ATOM 6310 C C . CYS B 1 401 ? 61.654 34.992 18.912 1.00 20.77 ? 591 CYS B C 1 ATOM 6311 O O . CYS B 1 401 ? 60.681 34.243 18.923 1.00 21.49 ? 591 CYS B O 1 ATOM 6312 C CB . CYS B 1 401 ? 61.467 36.106 21.135 1.00 25.02 ? 591 CYS B CB 1 ATOM 6313 S SG . CYS B 1 401 ? 61.191 37.807 20.565 1.00 29.99 ? 591 CYS B SG 1 ATOM 6314 N N . ALA B 1 402 ? 62.123 35.552 17.802 1.00 19.15 ? 592 ALA B N 1 ATOM 6315 C CA . ALA B 1 402 ? 61.506 35.318 16.499 1.00 18.06 ? 592 ALA B CA 1 ATOM 6316 C C . ALA B 1 402 ? 62.254 36.076 15.414 1.00 19.83 ? 592 ALA B C 1 ATOM 6317 O O . ALA B 1 402 ? 63.112 36.909 15.704 1.00 23.31 ? 592 ALA B O 1 ATOM 6318 C CB . ALA B 1 402 ? 60.048 35.760 16.515 1.00 10.32 ? 592 ALA B CB 1 ATOM 6319 N N . ASP B 1 403 ? 61.918 35.786 14.163 1.00 20.87 ? 593 ASP B N 1 ATOM 6320 C CA . ASP B 1 403 ? 62.549 36.447 13.029 1.00 24.42 ? 593 ASP B CA 1 ATOM 6321 C C . ASP B 1 403 ? 62.321 37.958 13.094 1.00 21.28 ? 593 ASP B C 1 ATOM 6322 O O . ASP B 1 403 ? 61.192 38.435 12.980 1.00 17.33 ? 593 ASP B O 1 ATOM 6323 C CB . ASP B 1 403 ? 61.985 35.890 11.718 1.00 28.43 ? 593 ASP B CB 1 ATOM 6324 C CG . ASP B 1 403 ? 62.563 36.575 10.492 1.00 37.24 ? 593 ASP B CG 1 ATOM 6325 O OD1 . ASP B 1 403 ? 62.118 36.248 9.371 1.00 44.06 ? 593 ASP B OD1 1 ATOM 6326 O OD2 . ASP B 1 403 ? 63.460 37.436 10.643 1.00 38.15 ? 593 ASP B OD2 1 ATOM 6327 N N . GLY B 1 404 ? 63.406 38.701 13.286 1.00 18.06 ? 594 GLY B N 1 ATOM 6328 C CA . GLY B 1 404 ? 63.315 40.144 13.362 1.00 13.79 ? 594 GLY B CA 1 ATOM 6329 C C . GLY B 1 404 ? 62.789 40.637 14.692 1.00 18.35 ? 594 GLY B C 1 ATOM 6330 O O . GLY B 1 404 ? 62.410 41.804 14.815 1.00 18.96 ? 594 GLY B O 1 ATOM 6331 N N . LYS B 1 405 ? 62.769 39.765 15.698 1.00 18.63 ? 595 LYS B N 1 ATOM 6332 C CA . LYS B 1 405 ? 62.268 40.158 17.011 1.00 19.36 ? 595 LYS B CA 1 ATOM 6333 C C . LYS B 1 405 ? 63.143 39.695 18.172 1.00 17.57 ? 595 LYS B C 1 ATOM 6334 O O . LYS B 1 405 ? 63.737 38.620 18.122 1.00 24.12 ? 595 LYS B O 1 ATOM 6335 C CB . LYS B 1 405 ? 60.840 39.637 17.189 1.00 17.96 ? 595 LYS B CB 1 ATOM 6336 C CG . LYS B 1 405 ? 59.929 39.980 16.016 1.00 7.62 ? 595 LYS B CG 1 ATOM 6337 C CD . LYS B 1 405 ? 58.474 39.664 16.299 1.00 2.21 ? 595 LYS B CD 1 ATOM 6338 C CE . LYS B 1 405 ? 57.874 40.664 17.269 1.00 12.69 ? 595 LYS B CE 1 ATOM 6339 N NZ . LYS B 1 405 ? 56.384 40.619 17.261 1.00 14.61 ? 595 LYS B NZ 1 ATOM 6340 N N . VAL B 1 406 ? 63.224 40.521 19.213 1.00 16.19 ? 596 VAL B N 1 ATOM 6341 C CA . VAL B 1 406 ? 64.016 40.202 20.401 1.00 16.97 ? 596 VAL B CA 1 ATOM 6342 C C . VAL B 1 406 ? 63.226 40.464 21.686 1.00 19.27 ? 596 VAL B C 1 ATOM 6343 O O . VAL B 1 406 ? 62.233 41.197 21.681 1.00 14.57 ? 596 VAL B O 1 ATOM 6344 C CB . VAL B 1 406 ? 65.330 41.025 20.454 1.00 12.02 ? 596 VAL B CB 1 ATOM 6345 C CG1 . VAL B 1 406 ? 66.217 40.654 19.291 1.00 12.43 ? 596 VAL B CG1 1 ATOM 6346 C CG2 . VAL B 1 406 ? 65.024 42.508 20.424 1.00 7.60 ? 596 VAL B CG2 1 ATOM 6347 N N . CYS B 1 407 ? 63.676 39.862 22.784 1.00 20.71 ? 597 CYS B N 1 ATOM 6348 C CA . CYS B 1 407 ? 63.012 40.019 24.076 1.00 19.60 ? 597 CYS B CA 1 ATOM 6349 C C . CYS B 1 407 ? 63.428 41.287 24.787 1.00 15.90 ? 597 CYS B C 1 ATOM 6350 O O . CYS B 1 407 ? 64.599 41.479 25.096 1.00 16.58 ? 597 CYS B O 1 ATOM 6351 C CB . CYS B 1 407 ? 63.311 38.829 24.989 1.00 21.47 ? 597 CYS B CB 1 ATOM 6352 S SG . CYS B 1 407 ? 62.600 37.254 24.421 1.00 29.64 ? 597 CYS B SG 1 ATOM 6353 N N . SER B 1 408 ? 62.456 42.153 25.047 1.00 18.66 ? 598 SER B N 1 ATOM 6354 C CA . SER B 1 408 ? 62.719 43.402 25.739 1.00 16.48 ? 598 SER B CA 1 ATOM 6355 C C . SER B 1 408 ? 61.717 43.528 26.871 1.00 18.28 ? 598 SER B C 1 ATOM 6356 O O . SER B 1 408 ? 60.579 43.952 26.671 1.00 26.80 ? 598 SER B O 1 ATOM 6357 C CB . SER B 1 408 ? 62.586 44.583 24.781 1.00 11.11 ? 598 SER B CB 1 ATOM 6358 O OG . SER B 1 408 ? 63.069 45.769 25.385 1.00 6.99 ? 598 SER B OG 1 ATOM 6359 N N . ASN B 1 409 ? 62.153 43.137 28.061 1.00 20.93 ? 599 ASN B N 1 ATOM 6360 C CA . ASN B 1 409 ? 61.325 43.176 29.256 1.00 21.32 ? 599 ASN B CA 1 ATOM 6361 C C . ASN B 1 409 ? 60.140 42.219 29.138 1.00 20.87 ? 599 ASN B C 1 ATOM 6362 O O . ASN B 1 409 ? 58.982 42.625 29.230 1.00 23.15 ? 599 ASN B O 1 ATOM 6363 C CB . ASN B 1 409 ? 60.826 44.599 29.518 1.00 19.17 ? 599 ASN B CB 1 ATOM 6364 C CG . ASN B 1 409 ? 60.217 44.751 30.900 1.00 31.97 ? 599 ASN B CG 1 ATOM 6365 O OD1 . ASN B 1 409 ? 59.612 45.775 31.216 1.00 38.51 ? 599 ASN B OD1 1 ATOM 6366 N ND2 . ASN B 1 409 ? 60.382 43.730 31.736 1.00 35.25 ? 599 ASN B ND2 1 ATOM 6367 N N . GLY B 1 410 ? 60.443 40.944 28.928 1.00 19.20 ? 600 GLY B N 1 ATOM 6368 C CA . GLY B 1 410 ? 59.396 39.945 28.812 1.00 22.49 ? 600 GLY B CA 1 ATOM 6369 C C . GLY B 1 410 ? 58.525 40.089 27.579 1.00 20.84 ? 600 GLY B C 1 ATOM 6370 O O . GLY B 1 410 ? 57.519 39.401 27.447 1.00 22.22 ? 600 GLY B O 1 ATOM 6371 N N . HIS B 1 411 ? 58.904 40.980 26.671 1.00 18.61 ? 601 HIS B N 1 ATOM 6372 C CA . HIS B 1 411 ? 58.131 41.187 25.454 1.00 16.86 ? 601 HIS B CA 1 ATOM 6373 C C . HIS B 1 411 ? 58.928 40.825 24.207 1.00 16.83 ? 601 HIS B C 1 ATOM 6374 O O . HIS B 1 411 ? 60.114 41.147 24.105 1.00 16.79 ? 601 HIS B O 1 ATOM 6375 C CB . HIS B 1 411 ? 57.693 42.648 25.356 1.00 17.87 ? 601 HIS B CB 1 ATOM 6376 C CG . HIS B 1 411 ? 56.667 43.046 26.369 1.00 18.63 ? 601 HIS B CG 1 ATOM 6377 N ND1 . HIS B 1 411 ? 55.367 42.591 26.329 1.00 18.42 ? 601 HIS B ND1 1 ATOM 6378 C CD2 . HIS B 1 411 ? 56.744 43.875 27.437 1.00 18.00 ? 601 HIS B CD2 1 ATOM 6379 C CE1 . HIS B 1 411 ? 54.685 43.127 27.326 1.00 17.63 ? 601 HIS B CE1 1 ATOM 6380 N NE2 . HIS B 1 411 ? 55.497 43.910 28.013 1.00 17.87 ? 601 HIS B NE2 1 ATOM 6381 N N . CYS B 1 412 ? 58.276 40.149 23.264 1.00 13.88 ? 602 CYS B N 1 ATOM 6382 C CA . CYS B 1 412 ? 58.922 39.778 22.010 1.00 14.17 ? 602 CYS B CA 1 ATOM 6383 C C . CYS B 1 412 ? 58.608 40.884 21.002 1.00 18.17 ? 602 CYS B C 1 ATOM 6384 O O . CYS B 1 412 ? 57.582 40.854 20.324 1.00 22.46 ? 602 CYS B O 1 ATOM 6385 C CB . CYS B 1 412 ? 58.391 38.435 21.510 1.00 13.69 ? 602 CYS B CB 1 ATOM 6386 S SG . CYS B 1 412 ? 59.236 37.854 20.006 1.00 28.56 ? 602 CYS B SG 1 ATOM 6387 N N . VAL B 1 413 ? 59.502 41.861 20.911 1.00 20.58 ? 603 VAL B N 1 ATOM 6388 C CA . VAL B 1 413 ? 59.309 43.002 20.024 1.00 19.65 ? 603 VAL B CA 1 ATOM 6389 C C . VAL B 1 413 ? 60.254 43.034 18.817 1.00 27.14 ? 603 VAL B C 1 ATOM 6390 O O . VAL B 1 413 ? 61.281 42.355 18.796 1.00 30.42 ? 603 VAL B O 1 ATOM 6391 C CB . VAL B 1 413 ? 59.469 44.316 20.820 1.00 10.85 ? 603 VAL B CB 1 ATOM 6392 C CG1 . VAL B 1 413 ? 58.592 44.272 22.050 1.00 1.00 ? 603 VAL B CG1 1 ATOM 6393 C CG2 . VAL B 1 413 ? 60.924 44.516 21.225 1.00 3.72 ? 603 VAL B CG2 1 ATOM 6394 N N . ASP B 1 414 ? 59.893 43.831 17.814 1.00 29.51 ? 604 ASP B N 1 ATOM 6395 C CA . ASP B 1 414 ? 60.703 43.972 16.608 1.00 34.07 ? 604 ASP B CA 1 ATOM 6396 C C . ASP B 1 414 ? 62.079 44.534 16.949 1.00 30.64 ? 604 ASP B C 1 ATOM 6397 O O . ASP B 1 414 ? 62.195 45.486 17.722 1.00 25.15 ? 604 ASP B O 1 ATOM 6398 C CB . ASP B 1 414 ? 60.002 44.895 15.604 1.00 39.91 ? 604 ASP B CB 1 ATOM 6399 C CG . ASP B 1 414 ? 60.899 45.286 14.437 1.00 47.46 ? 604 ASP B CG 1 ATOM 6400 O OD1 . ASP B 1 414 ? 61.450 44.385 13.769 1.00 50.73 ? 604 ASP B OD1 1 ATOM 6401 O OD2 . ASP B 1 414 ? 61.051 46.501 14.184 1.00 51.72 ? 604 ASP B OD2 1 ATOM 6402 N N . VAL B 1 415 ? 63.115 43.939 16.363 1.00 27.31 ? 605 VAL B N 1 ATOM 6403 C CA . VAL B 1 415 ? 64.489 44.364 16.600 1.00 26.64 ? 605 VAL B CA 1 ATOM 6404 C C . VAL B 1 415 ? 64.693 45.835 16.253 1.00 30.05 ? 605 VAL B C 1 ATOM 6405 O O . VAL B 1 415 ? 65.254 46.593 17.045 1.00 35.87 ? 605 VAL B O 1 ATOM 6406 C CB . VAL B 1 415 ? 65.484 43.525 15.769 1.00 28.62 ? 605 VAL B CB 1 ATOM 6407 C CG1 . VAL B 1 415 ? 66.912 43.883 16.149 1.00 30.73 ? 605 VAL B CG1 1 ATOM 6408 C CG2 . VAL B 1 415 ? 65.243 42.049 16.004 1.00 36.94 ? 605 VAL B CG2 1 ATOM 6409 N N . ALA B 1 416 ? 64.237 46.234 15.069 1.00 30.04 ? 606 ALA B N 1 ATOM 6410 C CA . ALA B 1 416 ? 64.374 47.613 14.610 1.00 29.80 ? 606 ALA B CA 1 ATOM 6411 C C . ALA B 1 416 ? 63.840 48.639 15.609 1.00 33.47 ? 606 ALA B C 1 ATOM 6412 O O . ALA B 1 416 ? 64.359 49.751 15.705 1.00 38.08 ? 606 ALA B O 1 ATOM 6413 C CB . ALA B 1 416 ? 63.670 47.783 13.275 1.00 25.59 ? 606 ALA B CB 1 ATOM 6414 N N . THR B 1 417 ? 62.805 48.265 16.352 1.00 33.53 ? 607 THR B N 1 ATOM 6415 C CA . THR B 1 417 ? 62.208 49.166 17.329 1.00 33.83 ? 607 THR B CA 1 ATOM 6416 C C . THR B 1 417 ? 62.550 48.744 18.752 1.00 35.31 ? 607 THR B C 1 ATOM 6417 O O . THR B 1 417 ? 61.943 49.223 19.709 1.00 39.69 ? 607 THR B O 1 ATOM 6418 C CB . THR B 1 417 ? 60.673 49.192 17.195 1.00 35.27 ? 607 THR B CB 1 ATOM 6419 O OG1 . THR B 1 417 ? 60.119 48.007 17.782 1.00 33.71 ? 607 THR B OG1 1 ATOM 6420 C CG2 . THR B 1 417 ? 60.273 49.244 15.726 1.00 36.77 ? 607 THR B CG2 1 ATOM 6421 N N . ALA B 1 418 ? 63.517 47.843 18.892 1.00 35.32 ? 608 ALA B N 1 ATOM 6422 C CA . ALA B 1 418 ? 63.918 47.364 20.211 1.00 32.87 ? 608 ALA B CA 1 ATOM 6423 C C . ALA B 1 418 ? 64.921 48.304 20.856 1.00 31.42 ? 608 ALA B C 1 ATOM 6424 O O . ALA B 1 418 ? 64.971 48.424 22.081 1.00 25.62 ? 608 ALA B O 1 ATOM 6425 C CB . ALA B 1 418 ? 64.513 45.968 20.105 1.00 33.08 ? 608 ALA B CB 1 ATOM 6426 N N . TYR B 1 419 ? 65.718 48.967 20.023 1.00 33.28 ? 609 TYR B N 1 ATOM 6427 C CA . TYR B 1 419 ? 66.728 49.895 20.515 1.00 35.84 ? 609 TYR B CA 1 ATOM 6428 C C . TYR B 1 419 ? 66.710 51.200 19.723 1.00 41.70 ? 609 TYR B C 1 ATOM 6429 O O . TYR B 1 419 ? 65.861 51.320 18.811 1.00 44.92 ? 609 TYR B O 1 ATOM 6430 C CB . TYR B 1 419 ? 68.115 49.259 20.419 1.00 29.43 ? 609 TYR B CB 1 ATOM 6431 C CG . TYR B 1 419 ? 68.136 47.784 20.744 1.00 23.89 ? 609 TYR B CG 1 ATOM 6432 C CD1 . TYR B 1 419 ? 68.009 46.826 19.734 1.00 14.86 ? 609 TYR B CD1 1 ATOM 6433 C CD2 . TYR B 1 419 ? 68.268 47.343 22.061 1.00 19.21 ? 609 TYR B CD2 1 ATOM 6434 C CE1 . TYR B 1 419 ? 68.017 45.466 20.029 1.00 13.54 ? 609 TYR B CE1 1 ATOM 6435 C CE2 . TYR B 1 419 ? 68.276 45.984 22.366 1.00 15.79 ? 609 TYR B CE2 1 ATOM 6436 C CZ . TYR B 1 419 ? 68.152 45.054 21.348 1.00 16.55 ? 609 TYR B CZ 1 ATOM 6437 O OH . TYR B 1 419 ? 68.169 43.715 21.653 1.00 25.66 ? 609 TYR B OH 1 ATOM 6438 O OXT . TYR B 1 419 ? 67.546 52.083 20.024 1.00 42.40 ? 609 TYR B OXT 1 HETATM 6439 C C1 . NAG C 2 . ? 90.137 22.187 25.404 1.00 31.13 ? 801 NAG A C1 1 HETATM 6440 C C2 . NAG C 2 . ? 89.375 23.480 25.625 1.00 26.35 ? 801 NAG A C2 1 HETATM 6441 C C3 . NAG C 2 . ? 89.364 24.248 24.307 1.00 31.57 ? 801 NAG A C3 1 HETATM 6442 C C4 . NAG C 2 . ? 90.803 24.463 23.794 1.00 31.75 ? 801 NAG A C4 1 HETATM 6443 C C5 . NAG C 2 . ? 91.631 23.158 23.823 1.00 30.41 ? 801 NAG A C5 1 HETATM 6444 C C6 . NAG C 2 . ? 93.112 23.424 23.638 1.00 32.38 ? 801 NAG A C6 1 HETATM 6445 C C7 . NAG C 2 . ? 87.693 23.309 27.331 1.00 27.90 ? 801 NAG A C7 1 HETATM 6446 C C8 . NAG C 2 . ? 86.539 24.241 27.655 1.00 29.45 ? 801 NAG A C8 1 HETATM 6447 N N2 . NAG C 2 . ? 88.024 23.181 26.052 1.00 29.59 ? 801 NAG A N2 1 HETATM 6448 O O3 . NAG C 2 . ? 88.727 25.504 24.501 1.00 26.56 ? 801 NAG A O3 1 HETATM 6449 O O4 . NAG C 2 . ? 90.770 24.958 22.439 1.00 35.36 ? 801 NAG A O4 1 HETATM 6450 O O5 . NAG C 2 . ? 91.496 22.483 25.090 1.00 32.80 ? 801 NAG A O5 1 HETATM 6451 O O6 . NAG C 2 . ? 93.671 22.433 22.760 1.00 37.54 ? 801 NAG A O6 1 HETATM 6452 O O7 . NAG C 2 . ? 88.280 22.718 28.237 1.00 32.59 ? 801 NAG A O7 1 HETATM 6453 C C1 . NAG D 2 . ? 90.582 26.317 22.245 1.00 34.85 ? 802 NAG A C1 1 HETATM 6454 C C2 . NAG D 2 . ? 91.260 26.713 20.925 1.00 31.66 ? 802 NAG A C2 1 HETATM 6455 C C3 . NAG D 2 . ? 90.948 28.163 20.570 1.00 32.32 ? 802 NAG A C3 1 HETATM 6456 C C4 . NAG D 2 . ? 89.435 28.328 20.529 1.00 34.96 ? 802 NAG A C4 1 HETATM 6457 C C5 . NAG D 2 . ? 88.828 27.929 21.880 1.00 32.45 ? 802 NAG A C5 1 HETATM 6458 C C6 . NAG D 2 . ? 87.311 28.015 21.873 1.00 28.60 ? 802 NAG A C6 1 HETATM 6459 C C7 . NAG D 2 . ? 93.346 25.738 20.214 1.00 34.35 ? 802 NAG A C7 1 HETATM 6460 C C8 . NAG D 2 . ? 94.848 25.641 20.411 1.00 29.34 ? 802 NAG A C8 1 HETATM 6461 N N2 . NAG D 2 . ? 92.692 26.541 21.047 1.00 34.67 ? 802 NAG A N2 1 HETATM 6462 O O3 . NAG D 2 . ? 91.503 28.478 19.300 1.00 24.26 ? 802 NAG A O3 1 HETATM 6463 O O4 . NAG D 2 . ? 89.094 29.686 20.212 1.00 37.93 ? 802 NAG A O4 1 HETATM 6464 O O5 . NAG D 2 . ? 89.164 26.557 22.185 1.00 34.92 ? 802 NAG A O5 1 HETATM 6465 O O6 . NAG D 2 . ? 86.751 27.392 23.022 1.00 35.45 ? 802 NAG A O6 1 HETATM 6466 O O7 . NAG D 2 . ? 92.796 25.092 19.318 1.00 30.61 ? 802 NAG A O7 1 HETATM 6467 C C1 . BMA E 3 . ? 88.299 29.864 19.103 1.00 33.11 ? 803 BMA A C1 1 HETATM 6468 C C2 . BMA E 3 . ? 87.741 31.277 19.128 1.00 35.97 ? 803 BMA A C2 1 HETATM 6469 C C3 . BMA E 3 . ? 86.873 31.479 17.887 1.00 37.20 ? 803 BMA A C3 1 HETATM 6470 C C4 . BMA E 3 . ? 87.693 31.206 16.625 1.00 37.45 ? 803 BMA A C4 1 HETATM 6471 C C5 . BMA E 3 . ? 88.339 29.818 16.705 1.00 38.06 ? 803 BMA A C5 1 HETATM 6472 C C6 . BMA E 3 . ? 89.301 29.650 15.556 1.00 31.46 ? 803 BMA A C6 1 HETATM 6473 O O2 . BMA E 3 . ? 88.820 32.204 19.115 1.00 35.32 ? 803 BMA A O2 1 HETATM 6474 O O3 . BMA E 3 . ? 86.376 32.832 17.853 1.00 37.23 ? 803 BMA A O3 1 HETATM 6475 O O4 . BMA E 3 . ? 86.830 31.268 15.473 1.00 39.38 ? 803 BMA A O4 1 HETATM 6476 O O5 . BMA E 3 . ? 89.108 29.684 17.931 1.00 38.19 ? 803 BMA A O5 1 HETATM 6477 O O6 . BMA E 3 . ? 90.190 30.783 15.512 1.00 29.97 ? 803 BMA A O6 1 HETATM 6478 C C1 . NAG F 2 . ? 87.230 32.101 14.442 1.00 37.75 ? 804 NAG A C1 1 HETATM 6479 C C2 . NAG F 2 . ? 86.555 31.634 13.148 1.00 35.50 ? 804 NAG A C2 1 HETATM 6480 C C3 . NAG F 2 . ? 86.764 32.634 12.009 1.00 33.96 ? 804 NAG A C3 1 HETATM 6481 C C4 . NAG F 2 . ? 86.393 34.038 12.473 1.00 33.69 ? 804 NAG A C4 1 HETATM 6482 C C5 . NAG F 2 . ? 87.189 34.379 13.725 1.00 32.93 ? 804 NAG A C5 1 HETATM 6483 C C6 . NAG F 2 . ? 86.873 35.776 14.231 1.00 31.72 ? 804 NAG A C6 1 HETATM 6484 C C7 . NAG F 2 . ? 86.324 29.274 12.763 1.00 40.66 ? 804 NAG A C7 1 HETATM 6485 C C8 . NAG F 2 . ? 86.776 28.104 11.906 1.00 40.21 ? 804 NAG A C8 1 HETATM 6486 N N2 . NAG F 2 . ? 87.104 30.347 12.775 1.00 38.04 ? 804 NAG A N2 1 HETATM 6487 O O3 . NAG F 2 . ? 85.955 32.267 10.903 1.00 30.50 ? 804 NAG A O3 1 HETATM 6488 O O4 . NAG F 2 . ? 86.668 34.984 11.454 1.00 35.03 ? 804 NAG A O4 1 HETATM 6489 O O5 . NAG F 2 . ? 86.846 33.445 14.771 1.00 38.59 ? 804 NAG A O5 1 HETATM 6490 O O6 . NAG F 2 . ? 87.404 35.989 15.529 1.00 31.39 ? 804 NAG A O6 1 HETATM 6491 O O7 . NAG F 2 . ? 85.276 29.205 13.403 1.00 40.71 ? 804 NAG A O7 1 HETATM 6492 C C1 . MAN G 4 . ? 85.052 32.971 17.423 1.00 34.33 ? 805 MAN A C1 1 HETATM 6493 C C2 . MAN G 4 . ? 84.728 34.466 17.242 1.00 37.41 ? 805 MAN A C2 1 HETATM 6494 C C3 . MAN G 4 . ? 84.214 35.212 18.506 1.00 39.74 ? 805 MAN A C3 1 HETATM 6495 C C4 . MAN G 4 . ? 83.459 34.327 19.511 1.00 39.79 ? 805 MAN A C4 1 HETATM 6496 C C5 . MAN G 4 . ? 84.103 32.949 19.614 1.00 38.94 ? 805 MAN A C5 1 HETATM 6497 C C6 . MAN G 4 . ? 83.365 32.002 20.540 1.00 35.36 ? 805 MAN A C6 1 HETATM 6498 O O2 . MAN G 4 . ? 83.893 34.710 16.081 1.00 37.48 ? 805 MAN A O2 1 HETATM 6499 O O3 . MAN G 4 . ? 83.375 36.293 18.124 1.00 48.86 ? 805 MAN A O3 1 HETATM 6500 O O4 . MAN G 4 . ? 83.491 34.946 20.788 1.00 35.68 ? 805 MAN A O4 1 HETATM 6501 O O5 . MAN G 4 . ? 84.138 32.346 18.312 1.00 37.73 ? 805 MAN A O5 1 HETATM 6502 O O6 . MAN G 4 . ? 84.267 31.335 21.412 1.00 36.82 ? 805 MAN A O6 1 HETATM 6503 C C1 . NAG H 2 . ? 82.540 34.390 16.024 1.00 30.02 ? 806 NAG A C1 1 HETATM 6504 C C2 . NAG H 2 . ? 82.054 34.653 14.583 1.00 30.90 ? 806 NAG A C2 1 HETATM 6505 C C3 . NAG H 2 . ? 80.639 34.135 14.366 1.00 33.43 ? 806 NAG A C3 1 HETATM 6506 C C4 . NAG H 2 . ? 80.543 32.675 14.793 1.00 32.59 ? 806 NAG A C4 1 HETATM 6507 C C5 . NAG H 2 . ? 81.031 32.536 16.237 1.00 32.74 ? 806 NAG A C5 1 HETATM 6508 C C6 . NAG H 2 . ? 80.998 31.099 16.727 1.00 25.11 ? 806 NAG A C6 1 HETATM 6509 C C7 . NAG H 2 . ? 83.193 36.626 13.796 1.00 32.03 ? 806 NAG A C7 1 HETATM 6510 C C8 . NAG H 2 . ? 84.110 37.351 14.780 1.00 17.04 ? 806 NAG A C8 1 HETATM 6511 N N2 . NAG H 2 . ? 82.089 36.072 14.288 1.00 31.69 ? 806 NAG A N2 1 HETATM 6512 O O3 . NAG H 2 . ? 80.297 34.262 12.993 1.00 33.13 ? 806 NAG A O3 1 HETATM 6513 O O4 . NAG H 2 . ? 79.195 32.242 14.691 1.00 34.49 ? 806 NAG A O4 1 HETATM 6514 O O5 . NAG H 2 . ? 82.397 32.999 16.339 1.00 32.96 ? 806 NAG A O5 1 HETATM 6515 O O6 . NAG H 2 . ? 81.090 31.038 18.142 1.00 14.32 ? 806 NAG A O6 1 HETATM 6516 O O7 . NAG H 2 . ? 83.487 36.578 12.600 1.00 30.82 ? 806 NAG A O7 1 HETATM 6517 C C1 . MAN I 4 . ? 91.530 30.393 15.474 1.00 36.62 ? 807 MAN A C1 1 HETATM 6518 C C2 . MAN I 4 . ? 92.417 31.626 15.733 1.00 37.35 ? 807 MAN A C2 1 HETATM 6519 C C3 . MAN I 4 . ? 92.401 32.573 14.525 1.00 39.12 ? 807 MAN A C3 1 HETATM 6520 C C4 . MAN I 4 . ? 92.680 31.828 13.205 1.00 42.78 ? 807 MAN A C4 1 HETATM 6521 C C5 . MAN I 4 . ? 91.705 30.644 13.082 1.00 45.39 ? 807 MAN A C5 1 HETATM 6522 C C6 . MAN I 4 . ? 91.854 29.799 11.811 1.00 42.17 ? 807 MAN A C6 1 HETATM 6523 O O2 . MAN I 4 . ? 93.768 31.219 16.025 1.00 38.77 ? 807 MAN A O2 1 HETATM 6524 O O3 . MAN I 4 . ? 93.380 33.579 14.705 1.00 32.83 ? 807 MAN A O3 1 HETATM 6525 O O4 . MAN I 4 . ? 92.489 32.726 12.115 1.00 46.28 ? 807 MAN A O4 1 HETATM 6526 O O5 . MAN I 4 . ? 91.867 29.774 14.227 1.00 42.72 ? 807 MAN A O5 1 HETATM 6527 O O6 . MAN I 4 . ? 92.788 28.737 11.985 1.00 38.69 ? 807 MAN A O6 1 HETATM 6528 C C1 . NAG J 2 . ? 94.025 30.873 17.346 1.00 42.71 ? 808 NAG A C1 1 HETATM 6529 C C2 . NAG J 2 . ? 95.221 29.908 17.410 1.00 46.21 ? 808 NAG A C2 1 HETATM 6530 C C3 . NAG J 2 . ? 95.634 29.639 18.861 1.00 47.57 ? 808 NAG A C3 1 HETATM 6531 C C4 . NAG J 2 . ? 95.814 30.950 19.629 1.00 47.13 ? 808 NAG A C4 1 HETATM 6532 C C5 . NAG J 2 . ? 94.560 31.816 19.484 1.00 46.51 ? 808 NAG A C5 1 HETATM 6533 C C6 . NAG J 2 . ? 94.705 33.154 20.180 1.00 44.15 ? 808 NAG A C6 1 HETATM 6534 C C7 . NAG J 2 . ? 95.127 28.462 15.481 1.00 46.07 ? 808 NAG A C7 1 HETATM 6535 C C8 . NAG J 2 . ? 94.062 27.739 14.668 1.00 48.20 ? 808 NAG A C8 1 HETATM 6536 N N2 . NAG J 2 . ? 94.882 28.648 16.774 1.00 44.93 ? 808 NAG A N2 1 HETATM 6537 O O3 . NAG J 2 . ? 96.852 28.907 18.879 1.00 45.65 ? 808 NAG A O3 1 HETATM 6538 O O4 . NAG J 2 . ? 96.045 30.669 21.001 1.00 43.52 ? 808 NAG A O4 1 HETATM 6539 O O5 . NAG J 2 . ? 94.297 32.076 18.086 1.00 44.89 ? 808 NAG A O5 1 HETATM 6540 O O6 . NAG J 2 . ? 94.862 32.978 21.579 1.00 49.04 ? 808 NAG A O6 1 HETATM 6541 O O7 . NAG J 2 . ? 96.160 28.849 14.934 1.00 44.55 ? 808 NAG A O7 1 HETATM 6542 C C1 . FUC K 5 . ? 94.953 22.783 22.316 1.00 31.01 ? 809 FUC A C1 1 HETATM 6543 C C2 . FUC K 5 . ? 95.998 21.953 23.061 1.00 31.60 ? 809 FUC A C2 1 HETATM 6544 C C3 . FUC K 5 . ? 95.837 20.473 22.703 1.00 29.64 ? 809 FUC A C3 1 HETATM 6545 C C4 . FUC K 5 . ? 95.877 20.266 21.188 1.00 29.54 ? 809 FUC A C4 1 HETATM 6546 C C5 . FUC K 5 . ? 94.902 21.222 20.469 1.00 33.16 ? 809 FUC A C5 1 HETATM 6547 C C6 . FUC K 5 . ? 95.084 21.213 18.958 1.00 34.39 ? 809 FUC A C6 1 HETATM 6548 O O2 . FUC K 5 . ? 95.822 22.118 24.462 1.00 39.42 ? 809 FUC A O2 1 HETATM 6549 O O3 . FUC K 5 . ? 96.881 19.727 23.308 1.00 25.51 ? 809 FUC A O3 1 HETATM 6550 O O4 . FUC K 5 . ? 97.197 20.480 20.715 1.00 23.18 ? 809 FUC A O4 1 HETATM 6551 O O5 . FUC K 5 . ? 95.109 22.586 20.911 1.00 30.80 ? 809 FUC A O5 1 HETATM 6552 ZN ZN . ZN L 6 . ? 77.798 8.644 21.812 1.00 18.89 ? 700 ZN A ZN 1 HETATM 6553 CA CA . CA M 7 . ? 81.503 0.403 43.618 1.00 21.01 ? 701 CA A CA 1 HETATM 6554 CA CA . CA N 7 . ? 97.088 -5.343 39.059 1.00 20.93 ? 702 CA A CA 1 HETATM 6555 CA CA . CA O 7 . ? 83.846 5.791 62.284 1.00 23.21 ? 703 CA A CA 1 HETATM 6556 C C1 . NAG P 2 . ? 88.910 29.184 60.910 1.00 33.74 ? 801 NAG B C1 1 HETATM 6557 C C2 . NAG P 2 . ? 88.124 27.900 60.682 1.00 32.12 ? 801 NAG B C2 1 HETATM 6558 C C3 . NAG P 2 . ? 88.054 27.157 62.015 1.00 34.72 ? 801 NAG B C3 1 HETATM 6559 C C4 . NAG P 2 . ? 89.481 26.917 62.560 1.00 34.57 ? 801 NAG B C4 1 HETATM 6560 C C5 . NAG P 2 . ? 90.330 28.198 62.561 1.00 32.79 ? 801 NAG B C5 1 HETATM 6561 C C6 . NAG P 2 . ? 91.792 27.851 62.801 1.00 33.97 ? 801 NAG B C6 1 HETATM 6562 C C7 . NAG P 2 . ? 86.330 27.615 59.090 1.00 41.01 ? 801 NAG B C7 1 HETATM 6563 C C8 . NAG P 2 . ? 85.500 26.352 59.266 1.00 46.10 ? 801 NAG B C8 1 HETATM 6564 N N2 . NAG P 2 . ? 86.792 28.203 60.192 1.00 37.97 ? 801 NAG B N2 1 HETATM 6565 O O3 . NAG P 2 . ? 87.383 25.918 61.828 1.00 29.64 ? 801 NAG B O3 1 HETATM 6566 O O4 . NAG P 2 . ? 89.435 26.413 63.909 1.00 38.84 ? 801 NAG B O4 1 HETATM 6567 O O5 . NAG P 2 . ? 90.256 28.868 61.282 1.00 35.17 ? 801 NAG B O5 1 HETATM 6568 O O6 . NAG P 2 . ? 92.492 28.976 63.361 1.00 39.21 ? 801 NAG B O6 1 HETATM 6569 O O7 . NAG P 2 . ? 86.535 28.056 57.958 1.00 39.56 ? 801 NAG B O7 1 HETATM 6570 C C1 . NAG Q 2 . ? 89.290 25.049 64.067 1.00 39.06 ? 802 NAG B C1 1 HETATM 6571 C C2 . NAG Q 2 . ? 89.874 24.643 65.429 1.00 38.13 ? 802 NAG B C2 1 HETATM 6572 C C3 . NAG Q 2 . ? 89.501 23.197 65.782 1.00 40.61 ? 802 NAG B C3 1 HETATM 6573 C C4 . NAG Q 2 . ? 87.988 22.990 65.641 1.00 43.90 ? 802 NAG B C4 1 HETATM 6574 C C5 . NAG Q 2 . ? 87.568 23.388 64.229 1.00 41.10 ? 802 NAG B C5 1 HETATM 6575 C C6 . NAG Q 2 . ? 86.081 23.242 63.988 1.00 41.72 ? 802 NAG B C6 1 HETATM 6576 C C7 . NAG Q 2 . ? 91.933 25.597 66.257 1.00 31.88 ? 802 NAG B C7 1 HETATM 6577 C C8 . NAG Q 2 . ? 93.438 25.738 66.108 1.00 24.76 ? 802 NAG B C8 1 HETATM 6578 N N2 . NAG Q 2 . ? 91.319 24.775 65.410 1.00 34.36 ? 802 NAG B N2 1 HETATM 6579 O O3 . NAG Q 2 . ? 89.894 22.929 67.120 1.00 39.47 ? 802 NAG B O3 1 HETATM 6580 O O4 . NAG Q 2 . ? 87.631 21.615 65.910 1.00 45.83 ? 802 NAG B O4 1 HETATM 6581 O O5 . NAG Q 2 . ? 87.883 24.774 64.016 1.00 40.79 ? 802 NAG B O5 1 HETATM 6582 O O6 . NAG Q 2 . ? 85.344 24.118 64.828 1.00 46.99 ? 802 NAG B O6 1 HETATM 6583 O O7 . NAG Q 2 . ? 91.342 26.230 67.133 1.00 31.50 ? 802 NAG B O7 1 HETATM 6584 C C1 . BMA R 3 . ? 86.774 21.409 66.988 1.00 40.99 ? 803 BMA B C1 1 HETATM 6585 C C2 . BMA R 3 . ? 86.161 20.005 66.925 1.00 40.38 ? 803 BMA B C2 1 HETATM 6586 C C3 . BMA R 3 . ? 85.239 19.807 68.127 1.00 41.86 ? 803 BMA B C3 1 HETATM 6587 C C4 . BMA R 3 . ? 86.012 20.068 69.420 1.00 40.02 ? 803 BMA B C4 1 HETATM 6588 C C5 . BMA R 3 . ? 86.693 21.440 69.385 1.00 39.34 ? 803 BMA B C5 1 HETATM 6589 C C6 . BMA R 3 . ? 87.618 21.578 70.574 1.00 38.21 ? 803 BMA B C6 1 HETATM 6590 O O2 . BMA R 3 . ? 87.188 19.024 66.969 1.00 42.25 ? 803 BMA B O2 1 HETATM 6591 O O3 . BMA R 3 . ? 84.750 18.449 68.150 1.00 45.31 ? 803 BMA B O3 1 HETATM 6592 O O4 . BMA R 3 . ? 85.103 20.015 70.534 1.00 40.74 ? 803 BMA B O4 1 HETATM 6593 O O5 . BMA R 3 . ? 87.523 21.555 68.204 1.00 40.24 ? 803 BMA B O5 1 HETATM 6594 O O6 . BMA R 3 . ? 88.563 20.488 70.556 1.00 34.14 ? 803 BMA B O6 1 HETATM 6595 C C1 . NAG S 2 . ? 85.507 19.312 71.654 1.00 34.61 ? 804 NAG B C1 1 HETATM 6596 C C2 . NAG S 2 . ? 84.688 19.808 72.841 1.00 30.87 ? 804 NAG B C2 1 HETATM 6597 C C3 . NAG S 2 . ? 84.925 18.953 74.082 1.00 31.04 ? 804 NAG B C3 1 HETATM 6598 C C4 . NAG S 2 . ? 84.696 17.482 73.739 1.00 32.41 ? 804 NAG B C4 1 HETATM 6599 C C5 . NAG S 2 . ? 85.584 17.087 72.555 1.00 32.56 ? 804 NAG B C5 1 HETATM 6600 C C6 . NAG S 2 . ? 85.361 15.639 72.140 1.00 31.22 ? 804 NAG B C6 1 HETATM 6601 C C7 . NAG S 2 . ? 84.107 22.109 73.192 1.00 31.75 ? 804 NAG B C7 1 HETATM 6602 C C8 . NAG S 2 . ? 84.404 23.316 74.067 1.00 29.58 ? 804 NAG B C8 1 HETATM 6603 N N2 . NAG S 2 . ? 85.052 21.182 73.111 1.00 31.09 ? 804 NAG B N2 1 HETATM 6604 O O3 . NAG S 2 . ? 84.024 19.353 75.104 1.00 24.40 ? 804 NAG B O3 1 HETATM 6605 O O4 . NAG S 2 . ? 84.994 16.671 74.863 1.00 34.89 ? 804 NAG B O4 1 HETATM 6606 O O5 . NAG S 2 . ? 85.268 17.915 71.413 1.00 36.37 ? 804 NAG B O5 1 HETATM 6607 O O6 . NAG S 2 . ? 85.295 15.504 70.727 1.00 25.52 ? 804 NAG B O6 1 HETATM 6608 O O7 . NAG S 2 . ? 83.031 22.023 72.597 1.00 28.86 ? 804 NAG B O7 1 HETATM 6609 C C1 . MAN T 4 . ? 83.438 18.292 68.614 1.00 40.65 ? 805 MAN B C1 1 HETATM 6610 C C2 . MAN T 4 . ? 83.189 16.795 68.897 1.00 43.34 ? 805 MAN B C2 1 HETATM 6611 C C3 . MAN T 4 . ? 82.786 15.946 67.659 1.00 43.47 ? 805 MAN B C3 1 HETATM 6612 C C4 . MAN T 4 . ? 81.986 16.718 66.591 1.00 42.73 ? 805 MAN B C4 1 HETATM 6613 C C5 . MAN T 4 . ? 82.540 18.128 66.422 1.00 40.77 ? 805 MAN B C5 1 HETATM 6614 C C6 . MAN T 4 . ? 81.806 18.984 65.419 1.00 39.68 ? 805 MAN B C6 1 HETATM 6615 O O2 . MAN T 4 . ? 82.306 16.573 70.031 1.00 42.33 ? 805 MAN B O2 1 HETATM 6616 O O3 . MAN T 4 . ? 82.039 14.810 68.076 1.00 45.50 ? 805 MAN B O3 1 HETATM 6617 O O4 . MAN T 4 . ? 82.083 16.031 65.352 1.00 43.84 ? 805 MAN B O4 1 HETATM 6618 O O5 . MAN T 4 . ? 82.496 18.803 67.685 1.00 38.57 ? 805 MAN B O5 1 HETATM 6619 O O6 . MAN T 4 . ? 82.619 20.064 64.984 1.00 32.79 ? 805 MAN B O6 1 HETATM 6620 C C1 . NAG U 2 . ? 80.931 16.789 69.983 1.00 34.33 ? 806 NAG B C1 1 HETATM 6621 C C2 . NAG U 2 . ? 80.350 16.512 71.389 1.00 35.93 ? 806 NAG B C2 1 HETATM 6622 C C3 . NAG U 2 . ? 78.878 16.905 71.454 1.00 35.58 ? 806 NAG B C3 1 HETATM 6623 C C4 . NAG U 2 . ? 78.713 18.358 71.019 1.00 36.70 ? 806 NAG B C4 1 HETATM 6624 C C5 . NAG U 2 . ? 79.321 18.546 69.619 1.00 38.79 ? 806 NAG B C5 1 HETATM 6625 C C6 . NAG U 2 . ? 79.261 19.993 69.156 1.00 34.34 ? 806 NAG B C6 1 HETATM 6626 C C7 . NAG U 2 . ? 81.567 14.681 72.383 1.00 38.65 ? 806 NAG B C7 1 HETATM 6627 C C8 . NAG U 2 . ? 82.613 13.944 71.557 1.00 38.36 ? 806 NAG B C8 1 HETATM 6628 N N2 . NAG U 2 . ? 80.486 15.110 71.738 1.00 39.49 ? 806 NAG B N2 1 HETATM 6629 O O3 . NAG U 2 . ? 78.397 16.733 72.781 1.00 33.13 ? 806 NAG B O3 1 HETATM 6630 O O4 . NAG U 2 . ? 77.333 18.694 71.005 1.00 28.81 ? 806 NAG B O4 1 HETATM 6631 O O5 . NAG U 2 . ? 80.717 18.162 69.626 1.00 38.01 ? 806 NAG B O5 1 HETATM 6632 O O6 . NAG U 2 . ? 79.334 20.083 67.741 1.00 30.08 ? 806 NAG B O6 1 HETATM 6633 O O7 . NAG U 2 . ? 81.740 14.850 73.593 1.00 33.94 ? 806 NAG B O7 1 HETATM 6634 C C1 . MAN V 4 . ? 89.884 20.929 70.663 1.00 36.50 ? 807 MAN B C1 1 HETATM 6635 C C2 . MAN V 4 . ? 90.817 19.748 70.384 1.00 37.30 ? 807 MAN B C2 1 HETATM 6636 C C3 . MAN V 4 . ? 90.797 18.749 71.541 1.00 35.24 ? 807 MAN B C3 1 HETATM 6637 C C4 . MAN V 4 . ? 91.120 19.465 72.851 1.00 35.96 ? 807 MAN B C4 1 HETATM 6638 C C5 . MAN V 4 . ? 90.102 20.586 73.060 1.00 38.06 ? 807 MAN B C5 1 HETATM 6639 C C6 . MAN V 4 . ? 90.340 21.387 74.324 1.00 38.21 ? 807 MAN B C6 1 HETATM 6640 O O2 . MAN V 4 . ? 92.158 20.218 70.184 1.00 38.65 ? 807 MAN B O2 1 HETATM 6641 O O3 . MAN V 4 . ? 91.761 17.732 71.304 1.00 33.86 ? 807 MAN B O3 1 HETATM 6642 O O4 . MAN V 4 . ? 91.066 18.538 73.926 1.00 36.15 ? 807 MAN B O4 1 HETATM 6643 O O5 . MAN V 4 . ? 90.170 21.509 71.948 1.00 39.36 ? 807 MAN B O5 1 HETATM 6644 O O6 . MAN V 4 . ? 91.527 22.161 74.222 1.00 40.26 ? 807 MAN B O6 1 HETATM 6645 C C1 . NAG W 2 . ? 92.550 20.353 68.869 1.00 42.80 ? 808 NAG B C1 1 HETATM 6646 C C2 . NAG W 2 . ? 93.717 21.336 68.789 1.00 45.44 ? 808 NAG B C2 1 HETATM 6647 C C3 . NAG W 2 . ? 94.229 21.409 67.350 1.00 46.77 ? 808 NAG B C3 1 HETATM 6648 C C4 . NAG W 2 . ? 94.580 20.008 66.840 1.00 46.96 ? 808 NAG B C4 1 HETATM 6649 C C5 . NAG W 2 . ? 93.359 19.098 66.994 1.00 47.51 ? 808 NAG B C5 1 HETATM 6650 C C6 . NAG W 2 . ? 93.613 17.673 66.546 1.00 48.69 ? 808 NAG B C6 1 HETATM 6651 C C7 . NAG W 2 . ? 93.047 22.911 70.495 1.00 47.37 ? 808 NAG B C7 1 HETATM 6652 C C8 . NAG W 2 . ? 91.779 23.691 70.817 1.00 44.46 ? 808 NAG B C8 1 HETATM 6653 N N2 . NAG W 2 . ? 93.289 22.656 69.213 1.00 47.35 ? 808 NAG B N2 1 HETATM 6654 O O3 . NAG W 2 . ? 95.375 22.244 67.298 1.00 47.62 ? 808 NAG B O3 1 HETATM 6655 O O4 . NAG W 2 . ? 94.965 20.077 65.476 1.00 48.10 ? 808 NAG B O4 1 HETATM 6656 O O5 . NAG W 2 . ? 92.950 19.059 68.383 1.00 47.05 ? 808 NAG B O5 1 HETATM 6657 O O6 . NAG W 2 . ? 94.108 17.634 65.218 1.00 51.22 ? 808 NAG B O6 1 HETATM 6658 O O7 . NAG W 2 . ? 93.791 22.539 71.403 1.00 42.67 ? 808 NAG B O7 1 HETATM 6659 C C1 . FUC X 5 . ? 93.785 28.619 63.784 1.00 34.90 ? 809 FUC B C1 1 HETATM 6660 C C2 . FUC X 5 . ? 94.800 29.649 63.274 1.00 32.54 ? 809 FUC B C2 1 HETATM 6661 C C3 . FUC X 5 . ? 94.523 31.008 63.937 1.00 33.99 ? 809 FUC B C3 1 HETATM 6662 C C4 . FUC X 5 . ? 94.544 30.877 65.472 1.00 28.78 ? 809 FUC B C4 1 HETATM 6663 C C5 . FUC X 5 . ? 93.594 29.752 65.926 1.00 34.84 ? 809 FUC B C5 1 HETATM 6664 C C6 . FUC X 5 . ? 93.702 29.440 67.412 1.00 30.37 ? 809 FUC B C6 1 HETATM 6665 O O2 . FUC X 5 . ? 94.686 29.770 61.862 1.00 28.45 ? 809 FUC B O2 1 HETATM 6666 O O3 . FUC X 5 . ? 95.498 31.956 63.522 1.00 30.08 ? 809 FUC B O3 1 HETATM 6667 O O4 . FUC X 5 . ? 95.862 30.585 65.912 1.00 26.32 ? 809 FUC B O4 1 HETATM 6668 O O5 . FUC X 5 . ? 93.888 28.520 65.210 1.00 36.52 ? 809 FUC B O5 1 HETATM 6669 ZN ZN . ZN Y 6 . ? 76.448 42.826 64.106 1.00 17.31 ? 700 ZN B ZN 1 HETATM 6670 CA CA . CA Z 7 . ? 80.874 51.428 42.465 1.00 23.04 ? 711 CA B CA 1 HETATM 6671 CA CA . CA AA 7 . ? 96.414 56.973 47.954 1.00 22.79 ? 712 CA B CA 1 HETATM 6672 CA CA . CA BA 7 . ? 85.122 45.355 23.784 1.00 20.52 ? 713 CA B CA 1 HETATM 6673 O O . HOH CA 8 . ? 92.505 3.614 35.146 1.00 20.61 ? 1 HOH A O 1 HETATM 6674 O O . HOH CA 8 . ? 87.312 -14.011 43.512 1.00 16.73 ? 2 HOH A O 1 HETATM 6675 O O . HOH CA 8 . ? 86.395 12.847 24.329 1.00 3.08 ? 3 HOH A O 1 HETATM 6676 O O . HOH CA 8 . ? 83.499 0.943 43.108 1.00 10.46 ? 4 HOH A O 1 HETATM 6677 O O . HOH CA 8 . ? 71.885 -12.940 20.732 1.00 1.00 ? 6 HOH A O 1 HETATM 6678 O O . HOH CA 8 . ? 68.116 9.730 64.505 1.00 11.00 ? 7 HOH A O 1 HETATM 6679 O O . HOH CA 8 . ? 88.898 -17.288 32.350 1.00 1.00 ? 8 HOH A O 1 HETATM 6680 O O . HOH CA 8 . ? 66.504 2.569 14.079 1.00 18.71 ? 10 HOH A O 1 HETATM 6681 O O . HOH CA 8 . ? 69.746 12.069 57.483 1.00 15.10 ? 13 HOH A O 1 HETATM 6682 O O . HOH CA 8 . ? 93.349 -7.028 18.610 1.00 10.69 ? 16 HOH A O 1 HETATM 6683 O O . HOH CA 8 . ? 87.519 11.122 14.113 1.00 15.76 ? 17 HOH A O 1 HETATM 6684 O O . HOH CA 8 . ? 103.105 -1.965 39.236 1.00 13.75 ? 19 HOH A O 1 HETATM 6685 O O . HOH CA 8 . ? 92.001 -3.270 43.771 1.00 10.80 ? 21 HOH A O 1 HETATM 6686 O O . HOH CA 8 . ? 78.859 -9.601 14.305 1.00 4.83 ? 22 HOH A O 1 HETATM 6687 O O . HOH CA 8 . ? 90.926 -14.261 22.655 1.00 17.23 ? 26 HOH A O 1 HETATM 6688 O O . HOH CA 8 . ? 89.584 10.122 12.863 1.00 5.76 ? 28 HOH A O 1 HETATM 6689 O O . HOH CA 8 . ? 72.240 -18.757 28.420 1.00 24.19 ? 31 HOH A O 1 HETATM 6690 O O . HOH CA 8 . ? 75.591 13.533 23.516 1.00 26.11 ? 33 HOH A O 1 HETATM 6691 O O . HOH CA 8 . ? 63.702 24.319 52.795 1.00 20.74 ? 35 HOH A O 1 HETATM 6692 O O . HOH CA 8 . ? 84.118 -11.767 18.553 1.00 28.78 ? 38 HOH A O 1 HETATM 6693 O O . HOH CA 8 . ? 92.451 -9.572 39.368 1.00 13.31 ? 39 HOH A O 1 HETATM 6694 O O . HOH CA 8 . ? 92.466 -10.338 42.009 1.00 17.13 ? 40 HOH A O 1 HETATM 6695 O O . HOH CA 8 . ? 72.780 -9.042 12.830 1.00 11.26 ? 43 HOH A O 1 HETATM 6696 O O . HOH CA 8 . ? 96.082 -2.517 26.126 1.00 43.22 ? 45 HOH A O 1 HETATM 6697 O O . HOH CA 8 . ? 74.357 3.362 60.848 1.00 29.84 ? 46 HOH A O 1 HETATM 6698 O O . HOH CA 8 . ? 78.121 -16.860 32.205 1.00 14.07 ? 47 HOH A O 1 HETATM 6699 O O . HOH CA 8 . ? 82.123 7.787 58.609 1.00 12.26 ? 49 HOH A O 1 HETATM 6700 O O . HOH CA 8 . ? 89.410 10.365 56.859 1.00 12.54 ? 50 HOH A O 1 HETATM 6701 O O . HOH CA 8 . ? 92.775 -7.902 35.848 1.00 30.46 ? 51 HOH A O 1 HETATM 6702 O O . HOH CA 8 . ? 90.508 -12.847 41.848 1.00 23.92 ? 54 HOH A O 1 HETATM 6703 O O . HOH CA 8 . ? 95.961 2.516 26.798 1.00 47.54 ? 55 HOH A O 1 HETATM 6704 O O . HOH CA 8 . ? 87.791 35.714 18.740 1.00 15.99 ? 56 HOH A O 1 HETATM 6705 O O . HOH CA 8 . ? 84.846 -4.777 44.881 1.00 32.87 ? 60 HOH A O 1 HETATM 6706 O O . HOH CA 8 . ? 67.946 -12.284 21.332 1.00 19.12 ? 63 HOH A O 1 HETATM 6707 O O . HOH CA 8 . ? 76.117 21.343 59.807 1.00 23.25 ? 64 HOH A O 1 HETATM 6708 O O . HOH CA 8 . ? 82.812 11.649 14.222 1.00 9.91 ? 67 HOH A O 1 HETATM 6709 O O . HOH CA 8 . ? 89.299 -5.795 35.026 1.00 18.62 ? 68 HOH A O 1 HETATM 6710 O O . HOH CA 8 . ? 64.521 -4.393 16.097 1.00 41.29 ? 69 HOH A O 1 HETATM 6711 O O . HOH CA 8 . ? 98.520 6.531 38.582 1.00 14.29 ? 72 HOH A O 1 HETATM 6712 O O . HOH CA 8 . ? 63.937 4.599 31.601 1.00 25.03 ? 74 HOH A O 1 HETATM 6713 O O . HOH CA 8 . ? 99.725 -9.798 38.611 1.00 20.04 ? 75 HOH A O 1 HETATM 6714 O O . HOH CA 8 . ? 73.459 -0.010 40.372 1.00 27.02 ? 76 HOH A O 1 HETATM 6715 O O . HOH CA 8 . ? 103.063 2.259 66.345 1.00 13.64 ? 79 HOH A O 1 HETATM 6716 O O . HOH CA 8 . ? 101.388 5.566 39.721 1.00 35.61 ? 80 HOH A O 1 HETATM 6717 O O . HOH CA 8 . ? 55.434 29.916 45.813 1.00 7.39 ? 82 HOH A O 1 HETATM 6718 O O . HOH CA 8 . ? 89.666 -17.967 29.451 1.00 17.16 ? 83 HOH A O 1 HETATM 6719 O O . HOH CA 8 . ? 86.254 3.417 65.911 1.00 11.76 ? 84 HOH A O 1 HETATM 6720 O O . HOH CA 8 . ? 79.787 -0.052 45.379 1.00 29.74 ? 86 HOH A O 1 HETATM 6721 O O . HOH CA 8 . ? 83.882 34.980 10.596 1.00 67.21 ? 89 HOH A O 1 HETATM 6722 O O . HOH CA 8 . ? 58.996 31.599 62.236 1.00 19.46 ? 90 HOH A O 1 HETATM 6723 O O . HOH CA 8 . ? 86.848 2.393 13.056 1.00 22.36 ? 91 HOH A O 1 HETATM 6724 O O . HOH CA 8 . ? 80.550 -13.611 36.440 1.00 23.71 ? 93 HOH A O 1 HETATM 6725 O O . HOH CA 8 . ? 73.864 18.097 63.061 1.00 22.31 ? 94 HOH A O 1 HETATM 6726 O O . HOH CA 8 . ? 64.964 21.256 46.081 1.00 23.40 ? 95 HOH A O 1 HETATM 6727 O O . HOH CA 8 . ? 62.805 -8.522 25.980 1.00 15.88 ? 96 HOH A O 1 HETATM 6728 O O . HOH CA 8 . ? 89.057 7.361 20.132 1.00 24.94 ? 97 HOH A O 1 HETATM 6729 O O . HOH CA 8 . ? 53.423 9.615 62.168 1.00 31.88 ? 98 HOH A O 1 HETATM 6730 O O . HOH CA 8 . ? 78.339 0.667 62.919 1.00 9.32 ? 100 HOH A O 1 HETATM 6731 O O . HOH CA 8 . ? 100.070 2.782 34.337 1.00 24.53 ? 101 HOH A O 1 HETATM 6732 O O . HOH CA 8 . ? 63.946 2.338 37.676 1.00 35.28 ? 102 HOH A O 1 HETATM 6733 O O . HOH CA 8 . ? 99.305 -1.134 27.317 1.00 28.89 ? 103 HOH A O 1 HETATM 6734 O O . HOH CA 8 . ? 94.091 3.087 16.482 1.00 11.98 ? 104 HOH A O 1 HETATM 6735 O O . HOH CA 8 . ? 78.455 16.012 67.395 1.00 47.79 ? 106 HOH A O 1 HETATM 6736 O O . HOH CA 8 . ? 67.699 14.204 71.983 1.00 26.76 ? 107 HOH A O 1 HETATM 6737 O O . HOH CA 8 . ? 93.605 17.321 26.908 1.00 28.09 ? 113 HOH A O 1 HETATM 6738 O O . HOH CA 8 . ? 76.034 15.060 61.757 1.00 25.60 ? 116 HOH A O 1 HETATM 6739 O O . HOH CA 8 . ? 64.746 7.738 61.232 1.00 21.39 ? 118 HOH A O 1 HETATM 6740 O O . HOH CA 8 . ? 109.669 -6.323 53.030 1.00 25.01 ? 119 HOH A O 1 HETATM 6741 O O . HOH CA 8 . ? 67.584 21.891 66.198 1.00 20.88 ? 120 HOH A O 1 HETATM 6742 O O . HOH CA 8 . ? 55.415 19.371 40.975 1.00 8.06 ? 122 HOH A O 1 HETATM 6743 O O . HOH CA 8 . ? 51.839 17.890 64.261 1.00 17.23 ? 128 HOH A O 1 HETATM 6744 O O . HOH CA 8 . ? 92.642 27.464 17.265 1.00 20.18 ? 131 HOH A O 1 HETATM 6745 O O . HOH CA 8 . ? 104.840 -6.178 55.180 1.00 20.78 ? 133 HOH A O 1 HETATM 6746 O O . HOH CA 8 . ? 92.232 8.872 54.845 1.00 31.12 ? 137 HOH A O 1 HETATM 6747 O O . HOH CA 8 . ? 76.673 -13.371 36.417 1.00 18.47 ? 139 HOH A O 1 HETATM 6748 O O . HOH CA 8 . ? 64.603 28.022 65.711 1.00 34.10 ? 140 HOH A O 1 HETATM 6749 O O . HOH CA 8 . ? 80.025 5.446 15.115 1.00 8.35 ? 142 HOH A O 1 HETATM 6750 O O . HOH CA 8 . ? 50.987 9.844 60.441 1.00 36.60 ? 145 HOH A O 1 HETATM 6751 O O . HOH CA 8 . ? 102.273 7.713 62.134 1.00 24.95 ? 146 HOH A O 1 HETATM 6752 O O . HOH CA 8 . ? 92.233 -14.966 29.354 1.00 40.85 ? 147 HOH A O 1 HETATM 6753 O O . HOH CA 8 . ? 56.988 6.258 50.266 1.00 29.47 ? 150 HOH A O 1 HETATM 6754 O O . HOH CA 8 . ? 52.276 12.299 56.473 1.00 16.21 ? 151 HOH A O 1 HETATM 6755 O O . HOH CA 8 . ? 93.093 -4.491 33.323 1.00 8.77 ? 152 HOH A O 1 HETATM 6756 O O . HOH CA 8 . ? 76.631 7.148 21.099 1.00 4.08 ? 153 HOH A O 1 HETATM 6757 O O . HOH CA 8 . ? 76.214 14.949 18.885 1.00 12.51 ? 154 HOH A O 1 HETATM 6758 O O . HOH DA 8 . ? 70.271 64.114 65.411 1.00 11.39 ? 5 HOH B O 1 HETATM 6759 O O . HOH DA 8 . ? 69.362 41.780 20.552 1.00 9.66 ? 9 HOH B O 1 HETATM 6760 O O . HOH DA 8 . ? 72.412 42.399 61.758 1.00 12.87 ? 11 HOH B O 1 HETATM 6761 O O . HOH DA 8 . ? 63.579 48.341 57.246 1.00 14.87 ? 12 HOH B O 1 HETATM 6762 O O . HOH DA 8 . ? 71.090 39.339 27.889 1.00 20.08 ? 14 HOH B O 1 HETATM 6763 O O . HOH DA 8 . ? 69.556 37.341 20.263 1.00 12.23 ? 15 HOH B O 1 HETATM 6764 O O . HOH DA 8 . ? 91.738 61.738 44.938 1.00 2.80 ? 18 HOH B O 1 HETATM 6765 O O . HOH DA 8 . ? 63.171 40.304 28.685 1.00 1.81 ? 20 HOH B O 1 HETATM 6766 O O . HOH DA 8 . ? 64.383 27.550 32.392 1.00 2.10 ? 23 HOH B O 1 HETATM 6767 O O . HOH DA 8 . ? 89.010 66.048 64.347 1.00 26.78 ? 24 HOH B O 1 HETATM 6768 O O . HOH DA 8 . ? 81.232 46.173 67.270 1.00 25.88 ? 27 HOH B O 1 HETATM 6769 O O . HOH DA 8 . ? 98.171 63.438 46.297 1.00 18.92 ? 29 HOH B O 1 HETATM 6770 O O . HOH DA 8 . ? 51.314 31.313 22.207 1.00 25.17 ? 30 HOH B O 1 HETATM 6771 O O . HOH DA 8 . ? 83.304 54.257 74.883 1.00 11.92 ? 34 HOH B O 1 HETATM 6772 O O . HOH DA 8 . ? 94.423 42.669 31.657 1.00 34.43 ? 36 HOH B O 1 HETATM 6773 O O . HOH DA 8 . ? 100.923 46.168 47.298 1.00 21.32 ? 37 HOH B O 1 HETATM 6774 O O . HOH DA 8 . ? 69.623 37.063 13.157 1.00 21.13 ? 41 HOH B O 1 HETATM 6775 O O . HOH DA 8 . ? 91.618 61.318 47.538 1.00 10.01 ? 42 HOH B O 1 HETATM 6776 O O . HOH DA 8 . ? 85.440 38.809 62.129 1.00 20.00 ? 44 HOH B O 1 HETATM 6777 O O . HOH DA 8 . ? 72.724 51.374 45.994 1.00 41.78 ? 48 HOH B O 1 HETATM 6778 O O . HOH DA 8 . ? 75.197 28.596 47.909 1.00 22.93 ? 52 HOH B O 1 HETATM 6779 O O . HOH DA 8 . ? 65.355 63.746 64.226 1.00 30.24 ? 53 HOH B O 1 HETATM 6780 O O . HOH DA 8 . ? 64.634 29.989 38.845 1.00 15.58 ? 57 HOH B O 1 HETATM 6781 O O . HOH DA 8 . ? 71.471 52.733 76.397 1.00 18.88 ? 58 HOH B O 1 HETATM 6782 O O . HOH DA 8 . ? 67.754 67.160 65.401 1.00 13.22 ? 59 HOH B O 1 HETATM 6783 O O . HOH DA 8 . ? 71.513 50.034 17.083 1.00 37.55 ? 61 HOH B O 1 HETATM 6784 O O . HOH DA 8 . ? 86.806 35.332 21.996 1.00 19.80 ? 62 HOH B O 1 HETATM 6785 O O . HOH DA 8 . ? 53.779 39.457 27.809 1.00 35.79 ? 65 HOH B O 1 HETATM 6786 O O . HOH DA 8 . ? 79.870 35.495 19.004 1.00 21.32 ? 66 HOH B O 1 HETATM 6787 O O . HOH DA 8 . ? 92.123 59.666 51.107 1.00 25.14 ? 70 HOH B O 1 HETATM 6788 O O . HOH DA 8 . ? 62.523 36.603 37.336 1.00 15.79 ? 71 HOH B O 1 HETATM 6789 O O . HOH DA 8 . ? 61.004 41.722 35.892 1.00 15.34 ? 73 HOH B O 1 HETATM 6790 O O . HOH DA 8 . ? 82.042 36.334 60.688 1.00 14.73 ? 77 HOH B O 1 HETATM 6791 O O . HOH DA 8 . ? 52.442 27.301 20.721 1.00 32.88 ? 78 HOH B O 1 HETATM 6792 O O . HOH DA 8 . ? 80.891 33.829 59.144 1.00 32.29 ? 81 HOH B O 1 HETATM 6793 O O . HOH DA 8 . ? 77.779 68.490 54.026 1.00 25.02 ? 85 HOH B O 1 HETATM 6794 O O . HOH DA 8 . ? 90.704 45.400 30.685 1.00 37.35 ? 87 HOH B O 1 HETATM 6795 O O . HOH DA 8 . ? 58.837 57.685 69.283 1.00 27.74 ? 88 HOH B O 1 HETATM 6796 O O . HOH DA 8 . ? 71.223 60.095 72.987 1.00 16.19 ? 92 HOH B O 1 HETATM 6797 O O . HOH DA 8 . ? 85.551 40.562 28.273 1.00 60.29 ? 99 HOH B O 1 HETATM 6798 O O . HOH DA 8 . ? 52.038 34.316 41.162 1.00 26.15 ? 105 HOH B O 1 HETATM 6799 O O . HOH DA 8 . ? 83.633 43.316 27.818 1.00 10.82 ? 108 HOH B O 1 HETATM 6800 O O . HOH DA 8 . ? 70.184 35.814 36.960 1.00 25.96 ? 110 HOH B O 1 HETATM 6801 O O . HOH DA 8 . ? 68.556 34.523 33.742 1.00 27.40 ? 111 HOH B O 1 HETATM 6802 O O . HOH DA 8 . ? 88.589 57.170 51.322 1.00 17.59 ? 112 HOH B O 1 HETATM 6803 O O . HOH DA 8 . ? 52.609 37.133 41.448 1.00 34.68 ? 114 HOH B O 1 HETATM 6804 O O . HOH DA 8 . ? 70.940 70.380 57.706 1.00 8.59 ? 115 HOH B O 1 HETATM 6805 O O . HOH DA 8 . ? 68.201 31.292 29.477 1.00 10.16 ? 117 HOH B O 1 HETATM 6806 O O . HOH DA 8 . ? 91.595 58.101 67.618 1.00 32.69 ? 121 HOH B O 1 HETATM 6807 O O . HOH DA 8 . ? 94.566 17.835 71.800 1.00 37.03 ? 123 HOH B O 1 HETATM 6808 O O . HOH DA 8 . ? 87.701 47.318 20.961 1.00 23.52 ? 124 HOH B O 1 HETATM 6809 O O . HOH DA 8 . ? 64.126 47.797 59.983 1.00 12.02 ? 125 HOH B O 1 HETATM 6810 O O . HOH DA 8 . ? 67.654 24.948 19.851 1.00 19.41 ? 126 HOH B O 1 HETATM 6811 O O . HOH DA 8 . ? 93.278 40.787 35.679 1.00 37.26 ? 127 HOH B O 1 HETATM 6812 O O . HOH DA 8 . ? 69.417 31.872 33.387 1.00 29.58 ? 129 HOH B O 1 HETATM 6813 O O . HOH DA 8 . ? 89.573 29.474 66.474 1.00 40.20 ? 130 HOH B O 1 HETATM 6814 O O . HOH DA 8 . ? 93.638 39.209 27.411 1.00 18.84 ? 132 HOH B O 1 HETATM 6815 O O . HOH DA 8 . ? 100.702 50.237 26.042 1.00 54.03 ? 134 HOH B O 1 HETATM 6816 O O . HOH DA 8 . ? 62.096 60.300 58.654 1.00 5.82 ? 135 HOH B O 1 HETATM 6817 O O . HOH DA 8 . ? 74.864 28.797 37.785 1.00 26.72 ? 136 HOH B O 1 HETATM 6818 O O . HOH DA 8 . ? 108.852 59.640 39.811 1.00 34.80 ? 141 HOH B O 1 HETATM 6819 O O . HOH DA 8 . ? 78.529 46.108 71.084 1.00 15.77 ? 143 HOH B O 1 HETATM 6820 O O . HOH DA 8 . ? 82.968 60.279 70.848 1.00 23.29 ? 144 HOH B O 1 HETATM 6821 O O . HOH DA 8 . ? 48.727 41.300 19.730 1.00 27.78 ? 148 HOH B O 1 HETATM 6822 O O . HOH DA 8 . ? 83.954 74.246 60.805 1.00 24.51 ? 149 HOH B O 1 HETATM 6823 O O . HOH DA 8 . ? 75.003 44.025 65.179 1.00 5.32 ? 155 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 HIS 1 191 ? ? ? A . n A 1 2 GLN 2 192 ? ? ? A . n A 1 3 LYS 3 193 ? ? ? A . n A 1 4 TYR 4 194 ? ? ? A . n A 1 5 ASN 5 195 195 ASN ASN A . n A 1 6 PRO 6 196 196 PRO PRO A . n A 1 7 PHE 7 197 197 PHE PHE A . n A 1 8 ARG 8 198 198 ARG ARG A . n A 1 9 PHE 9 199 199 PHE PHE A . n A 1 10 VAL 10 200 200 VAL VAL A . n A 1 11 GLU 11 201 201 GLU GLU A . n A 1 12 LEU 12 202 202 LEU LEU A . n A 1 13 VAL 13 203 203 VAL VAL A . n A 1 14 LEU 14 204 204 LEU LEU A . n A 1 15 VAL 15 205 205 VAL VAL A . n A 1 16 VAL 16 206 206 VAL VAL A . n A 1 17 ASP 17 207 207 ASP ASP A . n A 1 18 LYS 18 208 208 LYS LYS A . n A 1 19 ALA 19 209 209 ALA ALA A . n A 1 20 MET 20 210 210 MET MET A . n A 1 21 VAL 21 211 211 VAL VAL A . n A 1 22 THR 22 212 212 THR THR A . n A 1 23 LYS 23 213 213 LYS LYS A . n A 1 24 ASN 24 214 214 ASN ASN A . n A 1 25 ASN 25 215 215 ASN ASN A . n A 1 26 GLY 26 216 216 GLY GLY A . n A 1 27 ASP 27 217 217 ASP ASP A . n A 1 28 LEU 28 218 218 LEU LEU A . n A 1 29 ASP 29 219 219 ASP ASP A . n A 1 30 LYS 30 220 220 LYS LYS A . n A 1 31 ILE 31 221 221 ILE ILE A . n A 1 32 LYS 32 222 222 LYS LYS A . n A 1 33 THR 33 223 223 THR THR A . n A 1 34 ARG 34 224 224 ARG ARG A . n A 1 35 MET 35 225 225 MET MET A . n A 1 36 TYR 36 226 226 TYR TYR A . n A 1 37 GLU 37 227 227 GLU GLU A . n A 1 38 ILE 38 228 228 ILE ILE A . n A 1 39 VAL 39 229 229 VAL VAL A . n A 1 40 ASN 40 230 230 ASN ASN A . n A 1 41 THR 41 231 231 THR THR A . n A 1 42 VAL 42 232 232 VAL VAL A . n A 1 43 ASN 43 233 233 ASN ASN A . n A 1 44 GLU 44 234 234 GLU GLU A . n A 1 45 ILE 45 235 235 ILE ILE A . n A 1 46 TYR 46 236 236 TYR TYR A . n A 1 47 ARG 47 237 237 ARG ARG A . n A 1 48 TYR 48 238 238 TYR TYR A . n A 1 49 MET 49 239 239 MET MET A . n A 1 50 TYR 50 240 240 TYR TYR A . n A 1 51 ILE 51 241 241 ILE ILE A . n A 1 52 HIS 52 242 242 HIS HIS A . n A 1 53 VAL 53 243 243 VAL VAL A . n A 1 54 ALA 54 244 244 ALA ALA A . n A 1 55 LEU 55 245 245 LEU LEU A . n A 1 56 VAL 56 246 246 VAL VAL A . n A 1 57 GLY 57 247 247 GLY GLY A . n A 1 58 LEU 58 248 248 LEU LEU A . n A 1 59 GLU 59 249 249 GLU GLU A . n A 1 60 ILE 60 250 250 ILE ILE A . n A 1 61 TRP 61 251 251 TRP TRP A . n A 1 62 SER 62 252 252 SER SER A . n A 1 63 ASN 63 253 253 ASN ASN A . n A 1 64 GLU 64 254 254 GLU GLU A . n A 1 65 ASP 65 255 255 ASP ASP A . n A 1 66 LYS 66 256 256 LYS LYS A . n A 1 67 ILE 67 257 257 ILE ILE A . n A 1 68 THR 68 258 258 THR THR A . n A 1 69 VAL 69 259 259 VAL VAL A . n A 1 70 LYS 70 260 260 LYS LYS A . n A 1 71 PRO 71 261 261 PRO PRO A . n A 1 72 GLU 72 262 262 GLU GLU A . n A 1 73 ALA 73 263 263 ALA ALA A . n A 1 74 GLY 74 264 264 GLY GLY A . n A 1 75 TYR 75 265 265 TYR TYR A . n A 1 76 THR 76 266 266 THR THR A . n A 1 77 LEU 77 267 267 LEU LEU A . n A 1 78 ASN 78 268 268 ASN ASN A . n A 1 79 ALA 79 269 269 ALA ALA A . n A 1 80 PHE 80 270 270 PHE PHE A . n A 1 81 GLY 81 271 271 GLY GLY A . n A 1 82 GLU 82 272 272 GLU GLU A . n A 1 83 TRP 83 273 273 TRP TRP A . n A 1 84 ARG 84 274 274 ARG ARG A . n A 1 85 LYS 85 275 275 LYS LYS A . n A 1 86 THR 86 276 276 THR THR A . n A 1 87 ASP 87 277 277 ASP ASP A . n A 1 88 LEU 88 278 278 LEU LEU A . n A 1 89 LEU 89 279 279 LEU LEU A . n A 1 90 THR 90 280 280 THR THR A . n A 1 91 ARG 91 281 281 ARG ARG A . n A 1 92 LYS 92 282 282 LYS LYS A . n A 1 93 LYS 93 283 283 LYS LYS A . n A 1 94 HIS 94 284 284 HIS HIS A . n A 1 95 ASP 95 285 285 ASP ASP A . n A 1 96 ASN 96 286 286 ASN ASN A . n A 1 97 ALA 97 287 287 ALA ALA A . n A 1 98 GLN 98 288 288 GLN GLN A . n A 1 99 LEU 99 289 289 LEU LEU A . n A 1 100 LEU 100 290 290 LEU LEU A . n A 1 101 THR 101 291 291 THR THR A . n A 1 102 ALA 102 292 292 ALA ALA A . n A 1 103 ILE 103 293 293 ILE ILE A . n A 1 104 ASP 104 294 294 ASP ASP A . n A 1 105 LEU 105 295 295 LEU LEU A . n A 1 106 ASP 106 296 296 ASP ASP A . n A 1 107 ARG 107 297 297 ARG ARG A . n A 1 108 VAL 108 298 298 VAL VAL A . n A 1 109 ILE 109 299 299 ILE ILE A . n A 1 110 GLY 110 300 300 GLY GLY A . n A 1 111 LEU 111 301 301 LEU LEU A . n A 1 112 ALA 112 302 302 ALA ALA A . n A 1 113 TYR 113 303 303 TYR TYR A . n A 1 114 VAL 114 304 304 VAL VAL A . n A 1 115 GLY 115 305 305 GLY GLY A . n A 1 116 SER 116 306 306 SER SER A . n A 1 117 MET 117 307 307 MET MET A . n A 1 118 CYS 118 308 308 CYS CYS A . n A 1 119 HIS 119 309 309 HIS HIS A . n A 1 120 PRO 120 310 310 PRO PRO A . n A 1 121 LYS 121 311 311 LYS LYS A . n A 1 122 ARG 122 312 312 ARG ARG A . n A 1 123 SER 123 313 313 SER SER A . n A 1 124 THR 124 314 314 THR THR A . n A 1 125 GLY 125 315 315 GLY GLY A . n A 1 126 ILE 126 316 316 ILE ILE A . n A 1 127 ILE 127 317 317 ILE ILE A . n A 1 128 GLN 128 318 318 GLN GLN A . n A 1 129 ASP 129 319 319 ASP ASP A . n A 1 130 TYR 130 320 320 TYR TYR A . n A 1 131 SER 131 321 321 SER SER A . n A 1 132 GLU 132 322 322 GLU GLU A . n A 1 133 ILE 133 323 323 ILE ILE A . n A 1 134 ASN 134 324 324 ASN ASN A . n A 1 135 LEU 135 325 325 LEU LEU A . n A 1 136 VAL 136 326 326 VAL VAL A . n A 1 137 VAL 137 327 327 VAL VAL A . n A 1 138 ALA 138 328 328 ALA ALA A . n A 1 139 VAL 139 329 329 VAL VAL A . n A 1 140 ILE 140 330 330 ILE ILE A . n A 1 141 MET 141 331 331 MET MET A . n A 1 142 ALA 142 332 332 ALA ALA A . n A 1 143 HIS 143 333 333 HIS HIS A . n A 1 144 GLU 144 334 334 GLU GLU A . n A 1 145 MET 145 335 335 MET MET A . n A 1 146 GLY 146 336 336 GLY GLY A . n A 1 147 HIS 147 337 337 HIS HIS A . n A 1 148 ASN 148 338 338 ASN ASN A . n A 1 149 LEU 149 339 339 LEU LEU A . n A 1 150 GLY 150 340 340 GLY GLY A . n A 1 151 ILE 151 341 341 ILE ILE A . n A 1 152 ASN 152 342 342 ASN ASN A . n A 1 153 HIS 153 343 343 HIS HIS A . n A 1 154 ASP 154 344 344 ASP ASP A . n A 1 155 SER 155 345 345 SER SER A . n A 1 156 GLY 156 346 346 GLY GLY A . n A 1 157 TYR 157 347 347 TYR TYR A . n A 1 158 CYS 158 348 348 CYS CYS A . n A 1 159 SER 159 349 349 SER SER A . n A 1 160 CYS 160 350 350 CYS CYS A . n A 1 161 GLY 161 351 351 GLY GLY A . n A 1 162 ASP 162 352 352 ASP ASP A . n A 1 163 TYR 163 353 353 TYR TYR A . n A 1 164 ALA 164 354 354 ALA ALA A . n A 1 165 CYS 165 355 355 CYS CYS A . n A 1 166 ILE 166 356 356 ILE ILE A . n A 1 167 MET 167 357 357 MET MET A . n A 1 168 ARG 168 358 358 ARG ARG A . n A 1 169 PRO 169 359 359 PRO PRO A . n A 1 170 GLU 170 360 360 GLU GLU A . n A 1 171 ILE 171 361 361 ILE ILE A . n A 1 172 SER 172 362 362 SER SER A . n A 1 173 PRO 173 363 363 PRO PRO A . n A 1 174 GLU 174 364 364 GLU GLU A . n A 1 175 PRO 175 365 365 PRO PRO A . n A 1 176 SER 176 366 366 SER SER A . n A 1 177 THR 177 367 367 THR THR A . n A 1 178 PHE 178 368 368 PHE PHE A . n A 1 179 PHE 179 369 369 PHE PHE A . n A 1 180 SER 180 370 370 SER SER A . n A 1 181 ASN 181 371 371 ASN ASN A . n A 1 182 CYS 182 372 372 CYS CYS A . n A 1 183 SER 183 373 373 SER SER A . n A 1 184 TYR 184 374 374 TYR TYR A . n A 1 185 PHE 185 375 375 PHE PHE A . n A 1 186 GLU 186 376 376 GLU GLU A . n A 1 187 CYS 187 377 377 CYS CYS A . n A 1 188 TRP 188 378 378 TRP TRP A . n A 1 189 ASP 189 379 379 ASP ASP A . n A 1 190 PHE 190 380 380 PHE PHE A . n A 1 191 ILE 191 381 381 ILE ILE A . n A 1 192 MET 192 382 382 MET MET A . n A 1 193 ASN 193 383 383 ASN ASN A . n A 1 194 HIS 194 384 384 HIS HIS A . n A 1 195 ASN 195 385 385 ASN ASN A . n A 1 196 PRO 196 386 386 PRO PRO A . n A 1 197 GLU 197 387 387 GLU GLU A . n A 1 198 CYS 198 388 388 CYS CYS A . n A 1 199 ILE 199 389 389 ILE ILE A . n A 1 200 LEU 200 390 390 LEU LEU A . n A 1 201 ASN 201 391 391 ASN ASN A . n A 1 202 GLU 202 392 392 GLU GLU A . n A 1 203 PRO 203 393 393 PRO PRO A . n A 1 204 LEU 204 394 394 LEU LEU A . n A 1 205 GLY 205 395 395 GLY GLY A . n A 1 206 THR 206 396 396 THR THR A . n A 1 207 ASP 207 397 397 ASP ASP A . n A 1 208 ILE 208 398 398 ILE ILE A . n A 1 209 ILE 209 399 399 ILE ILE A . n A 1 210 SER 210 400 400 SER SER A . n A 1 211 PRO 211 401 401 PRO PRO A . n A 1 212 PRO 212 402 402 PRO PRO A . n A 1 213 VAL 213 403 403 VAL VAL A . n A 1 214 CYS 214 404 404 CYS CYS A . n A 1 215 GLY 215 405 405 GLY GLY A . n A 1 216 ASN 216 406 406 ASN ASN A . n A 1 217 GLU 217 407 407 GLU GLU A . n A 1 218 LEU 218 408 408 LEU LEU A . n A 1 219 LEU 219 409 409 LEU LEU A . n A 1 220 GLU 220 410 410 GLU GLU A . n A 1 221 VAL 221 411 411 VAL VAL A . n A 1 222 GLY 222 412 412 GLY GLY A . n A 1 223 GLU 223 413 413 GLU GLU A . n A 1 224 GLU 224 414 414 GLU GLU A . n A 1 225 CYS 225 415 415 CYS CYS A . n A 1 226 ASP 226 416 416 ASP ASP A . n A 1 227 CYS 227 417 417 CYS CYS A . n A 1 228 GLY 228 418 418 GLY GLY A . n A 1 229 THR 229 419 419 THR THR A . n A 1 230 PRO 230 420 420 PRO PRO A . n A 1 231 GLU 231 421 421 GLU GLU A . n A 1 232 ASN 232 422 422 ASN ASN A . n A 1 233 CYS 233 423 423 CYS CYS A . n A 1 234 GLN 234 424 424 GLN GLN A . n A 1 235 ASN 235 425 425 ASN ASN A . n A 1 236 GLU 236 426 426 GLU GLU A . n A 1 237 CYS 237 427 427 CYS CYS A . n A 1 238 CYS 238 428 428 CYS CYS A . n A 1 239 ASP 239 429 429 ASP ASP A . n A 1 240 ALA 240 430 430 ALA ALA A . n A 1 241 ALA 241 431 431 ALA ALA A . n A 1 242 THR 242 432 432 THR THR A . n A 1 243 CYS 243 433 433 CYS CYS A . n A 1 244 LYS 244 434 434 LYS LYS A . n A 1 245 LEU 245 435 435 LEU LEU A . n A 1 246 LYS 246 436 436 LYS LYS A . n A 1 247 SER 247 437 437 SER SER A . n A 1 248 GLY 248 438 438 GLY GLY A . n A 1 249 SER 249 439 439 SER SER A . n A 1 250 GLN 250 440 440 GLN GLN A . n A 1 251 CYS 251 441 441 CYS CYS A . n A 1 252 GLY 252 442 442 GLY GLY A . n A 1 253 HIS 253 443 443 HIS HIS A . n A 1 254 GLY 254 444 444 GLY GLY A . n A 1 255 ASP 255 445 445 ASP ASP A . n A 1 256 CYS 256 446 446 CYS CYS A . n A 1 257 CYS 257 447 447 CYS CYS A . n A 1 258 GLU 258 448 448 GLU GLU A . n A 1 259 GLN 259 449 449 GLN GLN A . n A 1 260 CYS 260 450 450 CYS CYS A . n A 1 261 LYS 261 451 451 LYS LYS A . n A 1 262 PHE 262 452 452 PHE PHE A . n A 1 263 SER 263 453 453 SER SER A . n A 1 264 LYS 264 454 454 LYS LYS A . n A 1 265 SER 265 455 455 SER SER A . n A 1 266 GLY 266 456 456 GLY GLY A . n A 1 267 THR 267 457 457 THR THR A . n A 1 268 GLU 268 458 458 GLU GLU A . n A 1 269 CYS 269 459 459 CYS CYS A . n A 1 270 ARG 270 460 460 ARG ARG A . n A 1 271 ALA 271 461 461 ALA ALA A . n A 1 272 SER 272 462 462 SER SER A . n A 1 273 MET 273 463 463 MET MET A . n A 1 274 SER 274 464 464 SER SER A . n A 1 275 GLU 275 465 465 GLU GLU A . n A 1 276 CYS 276 466 466 CYS CYS A . n A 1 277 ASP 277 467 467 ASP ASP A . n A 1 278 PRO 278 468 468 PRO PRO A . n A 1 279 ALA 279 469 469 ALA ALA A . n A 1 280 GLU 280 470 470 GLU GLU A . n A 1 281 HIS 281 471 471 HIS HIS A . n A 1 282 CYS 282 472 472 CYS CYS A . n A 1 283 THR 283 473 473 THR THR A . n A 1 284 GLY 284 474 474 GLY GLY A . n A 1 285 GLN 285 475 475 GLN GLN A . n A 1 286 SER 286 476 476 SER SER A . n A 1 287 SER 287 477 477 SER SER A . n A 1 288 GLU 288 478 478 GLU GLU A . n A 1 289 CYS 289 479 479 CYS CYS A . n A 1 290 PRO 290 480 480 PRO PRO A . n A 1 291 ALA 291 481 481 ALA ALA A . n A 1 292 ASP 292 482 482 ASP ASP A . n A 1 293 VAL 293 483 483 VAL VAL A . n A 1 294 PHE 294 484 484 PHE PHE A . n A 1 295 HIS 295 485 485 HIS HIS A . n A 1 296 LYS 296 486 486 LYS LYS A . n A 1 297 ASN 297 487 487 ASN ASN A . n A 1 298 GLY 298 488 488 GLY GLY A . n A 1 299 GLN 299 489 489 GLN GLN A . n A 1 300 PRO 300 490 490 PRO PRO A . n A 1 301 CYS 301 491 491 CYS CYS A . n A 1 302 LEU 302 492 492 LEU LEU A . n A 1 303 ASP 303 493 493 ASP ASP A . n A 1 304 ASN 304 494 494 ASN ASN A . n A 1 305 TYR 305 495 495 TYR TYR A . n A 1 306 GLY 306 496 496 GLY GLY A . n A 1 307 TYR 307 497 497 TYR TYR A . n A 1 308 CYS 308 498 498 CYS CYS A . n A 1 309 TYR 309 499 499 TYR TYR A . n A 1 310 ASN 310 500 500 ASN ASN A . n A 1 311 GLY 311 501 501 GLY GLY A . n A 1 312 ASN 312 502 502 ASN ASN A . n A 1 313 CYS 313 503 503 CYS CYS A . n A 1 314 PRO 314 504 504 PRO PRO A . n A 1 315 ILE 315 505 505 ILE ILE A . n A 1 316 MET 316 506 506 MET MET A . n A 1 317 TYR 317 507 507 TYR TYR A . n A 1 318 HIS 318 508 508 HIS HIS A . n A 1 319 GLN 319 509 509 GLN GLN A . n A 1 320 CYS 320 510 510 CYS CYS A . n A 1 321 TYR 321 511 511 TYR TYR A . n A 1 322 ASP 322 512 512 ASP ASP A . n A 1 323 LEU 323 513 513 LEU LEU A . n A 1 324 PHE 324 514 514 PHE PHE A . n A 1 325 GLY 325 515 515 GLY GLY A . n A 1 326 ALA 326 516 516 ALA ALA A . n A 1 327 ASP 327 517 517 ASP ASP A . n A 1 328 VAL 328 518 518 VAL VAL A . n A 1 329 TYR 329 519 519 TYR TYR A . n A 1 330 GLU 330 520 520 GLU GLU A . n A 1 331 ALA 331 521 521 ALA ALA A . n A 1 332 GLU 332 522 522 GLU GLU A . n A 1 333 ASP 333 523 523 ASP ASP A . n A 1 334 SER 334 524 524 SER SER A . n A 1 335 CYS 335 525 525 CYS CYS A . n A 1 336 PHE 336 526 526 PHE PHE A . n A 1 337 GLU 337 527 527 GLU GLU A . n A 1 338 ARG 338 528 528 ARG ARG A . n A 1 339 ASN 339 529 529 ASN ASN A . n A 1 340 GLN 340 530 530 GLN GLN A . n A 1 341 LYS 341 531 531 LYS LYS A . n A 1 342 GLY 342 532 532 GLY GLY A . n A 1 343 ASN 343 533 533 ASN ASN A . n A 1 344 TYR 344 534 534 TYR TYR A . n A 1 345 TYR 345 535 535 TYR TYR A . n A 1 346 GLY 346 536 536 GLY GLY A . n A 1 347 TYR 347 537 537 TYR TYR A . n A 1 348 CYS 348 538 538 CYS CYS A . n A 1 349 ARG 349 539 539 ARG ARG A . n A 1 350 LYS 350 540 540 LYS LYS A . n A 1 351 GLU 351 541 541 GLU GLU A . n A 1 352 ASN 352 542 542 ASN ASN A . n A 1 353 GLY 353 543 543 GLY GLY A . n A 1 354 ASN 354 544 544 ASN ASN A . n A 1 355 LYS 355 545 545 LYS LYS A . n A 1 356 ILE 356 546 546 ILE ILE A . n A 1 357 PRO 357 547 547 PRO PRO A . n A 1 358 CYS 358 548 548 CYS CYS A . n A 1 359 ALA 359 549 549 ALA ALA A . n A 1 360 PRO 360 550 550 PRO PRO A . n A 1 361 GLU 361 551 551 GLU GLU A . n A 1 362 ASP 362 552 552 ASP ASP A . n A 1 363 VAL 363 553 553 VAL VAL A . n A 1 364 LYS 364 554 554 LYS LYS A . n A 1 365 CYS 365 555 555 CYS CYS A . n A 1 366 GLY 366 556 556 GLY GLY A . n A 1 367 ARG 367 557 557 ARG ARG A . n A 1 368 LEU 368 558 558 LEU LEU A . n A 1 369 TYR 369 559 559 TYR TYR A . n A 1 370 CYS 370 560 560 CYS CYS A . n A 1 371 LYS 371 561 561 LYS LYS A . n A 1 372 ASP 372 562 562 ASP ASP A . n A 1 373 ASN 373 563 563 ASN ASN A . n A 1 374 SER 374 564 564 SER SER A . n A 1 375 PRO 375 565 565 PRO PRO A . n A 1 376 GLY 376 566 566 GLY GLY A . n A 1 377 GLN 377 567 567 GLN GLN A . n A 1 378 ASN 378 568 568 ASN ASN A . n A 1 379 ASN 379 569 569 ASN ASN A . n A 1 380 PRO 380 570 570 PRO PRO A . n A 1 381 CYS 381 571 571 CYS CYS A . n A 1 382 LYS 382 572 572 LYS LYS A . n A 1 383 MET 383 573 573 MET MET A . n A 1 384 PHE 384 574 574 PHE PHE A . n A 1 385 TYR 385 575 575 TYR TYR A . n A 1 386 SER 386 576 576 SER SER A . n A 1 387 ASN 387 577 577 ASN ASN A . n A 1 388 GLU 388 578 578 GLU GLU A . n A 1 389 ASP 389 579 579 ASP ASP A . n A 1 390 GLU 390 580 580 GLU GLU A . n A 1 391 HIS 391 581 581 HIS HIS A . n A 1 392 LYS 392 582 582 LYS LYS A . n A 1 393 GLY 393 583 583 GLY GLY A . n A 1 394 MET 394 584 584 MET MET A . n A 1 395 VAL 395 585 585 VAL VAL A . n A 1 396 LEU 396 586 586 LEU LEU A . n A 1 397 PRO 397 587 587 PRO PRO A . n A 1 398 GLY 398 588 588 GLY GLY A . n A 1 399 THR 399 589 589 THR THR A . n A 1 400 LYS 400 590 590 LYS LYS A . n A 1 401 CYS 401 591 591 CYS CYS A . n A 1 402 ALA 402 592 592 ALA ALA A . n A 1 403 ASP 403 593 593 ASP ASP A . n A 1 404 GLY 404 594 594 GLY GLY A . n A 1 405 LYS 405 595 595 LYS LYS A . n A 1 406 VAL 406 596 596 VAL VAL A . n A 1 407 CYS 407 597 597 CYS CYS A . n A 1 408 SER 408 598 598 SER SER A . n A 1 409 ASN 409 599 599 ASN ASN A . n A 1 410 GLY 410 600 600 GLY GLY A . n A 1 411 HIS 411 601 601 HIS HIS A . n A 1 412 CYS 412 602 602 CYS CYS A . n A 1 413 VAL 413 603 603 VAL VAL A . n A 1 414 ASP 414 604 604 ASP ASP A . n A 1 415 VAL 415 605 605 VAL VAL A . n A 1 416 ALA 416 606 606 ALA ALA A . n A 1 417 THR 417 607 607 THR THR A . n A 1 418 ALA 418 608 608 ALA ALA A . n A 1 419 TYR 419 609 609 TYR TYR A . n B 1 1 HIS 1 191 ? ? ? B . n B 1 2 GLN 2 192 ? ? ? B . n B 1 3 LYS 3 193 ? ? ? B . n B 1 4 TYR 4 194 ? ? ? B . n B 1 5 ASN 5 195 195 ASN ASN B . n B 1 6 PRO 6 196 196 PRO PRO B . n B 1 7 PHE 7 197 197 PHE PHE B . n B 1 8 ARG 8 198 198 ARG ARG B . n B 1 9 PHE 9 199 199 PHE PHE B . n B 1 10 VAL 10 200 200 VAL VAL B . n B 1 11 GLU 11 201 201 GLU GLU B . n B 1 12 LEU 12 202 202 LEU LEU B . n B 1 13 VAL 13 203 203 VAL VAL B . n B 1 14 LEU 14 204 204 LEU LEU B . n B 1 15 VAL 15 205 205 VAL VAL B . n B 1 16 VAL 16 206 206 VAL VAL B . n B 1 17 ASP 17 207 207 ASP ASP B . n B 1 18 LYS 18 208 208 LYS LYS B . n B 1 19 ALA 19 209 209 ALA ALA B . n B 1 20 MET 20 210 210 MET MET B . n B 1 21 VAL 21 211 211 VAL VAL B . n B 1 22 THR 22 212 212 THR THR B . n B 1 23 LYS 23 213 213 LYS LYS B . n B 1 24 ASN 24 214 214 ASN ASN B . n B 1 25 ASN 25 215 215 ASN ASN B . n B 1 26 GLY 26 216 216 GLY GLY B . n B 1 27 ASP 27 217 217 ASP ASP B . n B 1 28 LEU 28 218 218 LEU LEU B . n B 1 29 ASP 29 219 219 ASP ASP B . n B 1 30 LYS 30 220 220 LYS LYS B . n B 1 31 ILE 31 221 221 ILE ILE B . n B 1 32 LYS 32 222 222 LYS LYS B . n B 1 33 THR 33 223 223 THR THR B . n B 1 34 ARG 34 224 224 ARG ARG B . n B 1 35 MET 35 225 225 MET MET B . n B 1 36 TYR 36 226 226 TYR TYR B . n B 1 37 GLU 37 227 227 GLU GLU B . n B 1 38 ILE 38 228 228 ILE ILE B . n B 1 39 VAL 39 229 229 VAL VAL B . n B 1 40 ASN 40 230 230 ASN ASN B . n B 1 41 THR 41 231 231 THR THR B . n B 1 42 VAL 42 232 232 VAL VAL B . n B 1 43 ASN 43 233 233 ASN ASN B . n B 1 44 GLU 44 234 234 GLU GLU B . n B 1 45 ILE 45 235 235 ILE ILE B . n B 1 46 TYR 46 236 236 TYR TYR B . n B 1 47 ARG 47 237 237 ARG ARG B . n B 1 48 TYR 48 238 238 TYR TYR B . n B 1 49 MET 49 239 239 MET MET B . n B 1 50 TYR 50 240 240 TYR TYR B . n B 1 51 ILE 51 241 241 ILE ILE B . n B 1 52 HIS 52 242 242 HIS HIS B . n B 1 53 VAL 53 243 243 VAL VAL B . n B 1 54 ALA 54 244 244 ALA ALA B . n B 1 55 LEU 55 245 245 LEU LEU B . n B 1 56 VAL 56 246 246 VAL VAL B . n B 1 57 GLY 57 247 247 GLY GLY B . n B 1 58 LEU 58 248 248 LEU LEU B . n B 1 59 GLU 59 249 249 GLU GLU B . n B 1 60 ILE 60 250 250 ILE ILE B . n B 1 61 TRP 61 251 251 TRP TRP B . n B 1 62 SER 62 252 252 SER SER B . n B 1 63 ASN 63 253 253 ASN ASN B . n B 1 64 GLU 64 254 254 GLU GLU B . n B 1 65 ASP 65 255 255 ASP ASP B . n B 1 66 LYS 66 256 256 LYS LYS B . n B 1 67 ILE 67 257 257 ILE ILE B . n B 1 68 THR 68 258 258 THR THR B . n B 1 69 VAL 69 259 259 VAL VAL B . n B 1 70 LYS 70 260 260 LYS LYS B . n B 1 71 PRO 71 261 261 PRO PRO B . n B 1 72 GLU 72 262 262 GLU GLU B . n B 1 73 ALA 73 263 263 ALA ALA B . n B 1 74 GLY 74 264 264 GLY GLY B . n B 1 75 TYR 75 265 265 TYR TYR B . n B 1 76 THR 76 266 266 THR THR B . n B 1 77 LEU 77 267 267 LEU LEU B . n B 1 78 ASN 78 268 268 ASN ASN B . n B 1 79 ALA 79 269 269 ALA ALA B . n B 1 80 PHE 80 270 270 PHE PHE B . n B 1 81 GLY 81 271 271 GLY GLY B . n B 1 82 GLU 82 272 272 GLU GLU B . n B 1 83 TRP 83 273 273 TRP TRP B . n B 1 84 ARG 84 274 274 ARG ARG B . n B 1 85 LYS 85 275 275 LYS LYS B . n B 1 86 THR 86 276 276 THR THR B . n B 1 87 ASP 87 277 277 ASP ASP B . n B 1 88 LEU 88 278 278 LEU LEU B . n B 1 89 LEU 89 279 279 LEU LEU B . n B 1 90 THR 90 280 280 THR THR B . n B 1 91 ARG 91 281 281 ARG ARG B . n B 1 92 LYS 92 282 282 LYS LYS B . n B 1 93 LYS 93 283 283 LYS LYS B . n B 1 94 HIS 94 284 284 HIS HIS B . n B 1 95 ASP 95 285 285 ASP ASP B . n B 1 96 ASN 96 286 286 ASN ASN B . n B 1 97 ALA 97 287 287 ALA ALA B . n B 1 98 GLN 98 288 288 GLN GLN B . n B 1 99 LEU 99 289 289 LEU LEU B . n B 1 100 LEU 100 290 290 LEU LEU B . n B 1 101 THR 101 291 291 THR THR B . n B 1 102 ALA 102 292 292 ALA ALA B . n B 1 103 ILE 103 293 293 ILE ILE B . n B 1 104 ASP 104 294 294 ASP ASP B . n B 1 105 LEU 105 295 295 LEU LEU B . n B 1 106 ASP 106 296 296 ASP ASP B . n B 1 107 ARG 107 297 297 ARG ARG B . n B 1 108 VAL 108 298 298 VAL VAL B . n B 1 109 ILE 109 299 299 ILE ILE B . n B 1 110 GLY 110 300 300 GLY GLY B . n B 1 111 LEU 111 301 301 LEU LEU B . n B 1 112 ALA 112 302 302 ALA ALA B . n B 1 113 TYR 113 303 303 TYR TYR B . n B 1 114 VAL 114 304 304 VAL VAL B . n B 1 115 GLY 115 305 305 GLY GLY B . n B 1 116 SER 116 306 306 SER SER B . n B 1 117 MET 117 307 307 MET MET B . n B 1 118 CYS 118 308 308 CYS CYS B . n B 1 119 HIS 119 309 309 HIS HIS B . n B 1 120 PRO 120 310 310 PRO PRO B . n B 1 121 LYS 121 311 311 LYS LYS B . n B 1 122 ARG 122 312 312 ARG ARG B . n B 1 123 SER 123 313 313 SER SER B . n B 1 124 THR 124 314 314 THR THR B . n B 1 125 GLY 125 315 315 GLY GLY B . n B 1 126 ILE 126 316 316 ILE ILE B . n B 1 127 ILE 127 317 317 ILE ILE B . n B 1 128 GLN 128 318 318 GLN GLN B . n B 1 129 ASP 129 319 319 ASP ASP B . n B 1 130 TYR 130 320 320 TYR TYR B . n B 1 131 SER 131 321 321 SER SER B . n B 1 132 GLU 132 322 322 GLU GLU B . n B 1 133 ILE 133 323 323 ILE ILE B . n B 1 134 ASN 134 324 324 ASN ASN B . n B 1 135 LEU 135 325 325 LEU LEU B . n B 1 136 VAL 136 326 326 VAL VAL B . n B 1 137 VAL 137 327 327 VAL VAL B . n B 1 138 ALA 138 328 328 ALA ALA B . n B 1 139 VAL 139 329 329 VAL VAL B . n B 1 140 ILE 140 330 330 ILE ILE B . n B 1 141 MET 141 331 331 MET MET B . n B 1 142 ALA 142 332 332 ALA ALA B . n B 1 143 HIS 143 333 333 HIS HIS B . n B 1 144 GLU 144 334 334 GLU GLU B . n B 1 145 MET 145 335 335 MET MET B . n B 1 146 GLY 146 336 336 GLY GLY B . n B 1 147 HIS 147 337 337 HIS HIS B . n B 1 148 ASN 148 338 338 ASN ASN B . n B 1 149 LEU 149 339 339 LEU LEU B . n B 1 150 GLY 150 340 340 GLY GLY B . n B 1 151 ILE 151 341 341 ILE ILE B . n B 1 152 ASN 152 342 342 ASN ASN B . n B 1 153 HIS 153 343 343 HIS HIS B . n B 1 154 ASP 154 344 344 ASP ASP B . n B 1 155 SER 155 345 345 SER SER B . n B 1 156 GLY 156 346 346 GLY GLY B . n B 1 157 TYR 157 347 347 TYR TYR B . n B 1 158 CYS 158 348 348 CYS CYS B . n B 1 159 SER 159 349 349 SER SER B . n B 1 160 CYS 160 350 350 CYS CYS B . n B 1 161 GLY 161 351 351 GLY GLY B . n B 1 162 ASP 162 352 352 ASP ASP B . n B 1 163 TYR 163 353 353 TYR TYR B . n B 1 164 ALA 164 354 354 ALA ALA B . n B 1 165 CYS 165 355 355 CYS CYS B . n B 1 166 ILE 166 356 356 ILE ILE B . n B 1 167 MET 167 357 357 MET MET B . n B 1 168 ARG 168 358 358 ARG ARG B . n B 1 169 PRO 169 359 359 PRO PRO B . n B 1 170 GLU 170 360 360 GLU GLU B . n B 1 171 ILE 171 361 361 ILE ILE B . n B 1 172 SER 172 362 362 SER SER B . n B 1 173 PRO 173 363 363 PRO PRO B . n B 1 174 GLU 174 364 364 GLU GLU B . n B 1 175 PRO 175 365 365 PRO PRO B . n B 1 176 SER 176 366 366 SER SER B . n B 1 177 THR 177 367 367 THR THR B . n B 1 178 PHE 178 368 368 PHE PHE B . n B 1 179 PHE 179 369 369 PHE PHE B . n B 1 180 SER 180 370 370 SER SER B . n B 1 181 ASN 181 371 371 ASN ASN B . n B 1 182 CYS 182 372 372 CYS CYS B . n B 1 183 SER 183 373 373 SER SER B . n B 1 184 TYR 184 374 374 TYR TYR B . n B 1 185 PHE 185 375 375 PHE PHE B . n B 1 186 GLU 186 376 376 GLU GLU B . n B 1 187 CYS 187 377 377 CYS CYS B . n B 1 188 TRP 188 378 378 TRP TRP B . n B 1 189 ASP 189 379 379 ASP ASP B . n B 1 190 PHE 190 380 380 PHE PHE B . n B 1 191 ILE 191 381 381 ILE ILE B . n B 1 192 MET 192 382 382 MET MET B . n B 1 193 ASN 193 383 383 ASN ASN B . n B 1 194 HIS 194 384 384 HIS HIS B . n B 1 195 ASN 195 385 385 ASN ASN B . n B 1 196 PRO 196 386 386 PRO PRO B . n B 1 197 GLU 197 387 387 GLU GLU B . n B 1 198 CYS 198 388 388 CYS CYS B . n B 1 199 ILE 199 389 389 ILE ILE B . n B 1 200 LEU 200 390 390 LEU LEU B . n B 1 201 ASN 201 391 391 ASN ASN B . n B 1 202 GLU 202 392 392 GLU GLU B . n B 1 203 PRO 203 393 393 PRO PRO B . n B 1 204 LEU 204 394 394 LEU LEU B . n B 1 205 GLY 205 395 395 GLY GLY B . n B 1 206 THR 206 396 396 THR THR B . n B 1 207 ASP 207 397 397 ASP ASP B . n B 1 208 ILE 208 398 398 ILE ILE B . n B 1 209 ILE 209 399 399 ILE ILE B . n B 1 210 SER 210 400 400 SER SER B . n B 1 211 PRO 211 401 401 PRO PRO B . n B 1 212 PRO 212 402 402 PRO PRO B . n B 1 213 VAL 213 403 403 VAL VAL B . n B 1 214 CYS 214 404 404 CYS CYS B . n B 1 215 GLY 215 405 405 GLY GLY B . n B 1 216 ASN 216 406 406 ASN ASN B . n B 1 217 GLU 217 407 407 GLU GLU B . n B 1 218 LEU 218 408 408 LEU LEU B . n B 1 219 LEU 219 409 409 LEU LEU B . n B 1 220 GLU 220 410 410 GLU GLU B . n B 1 221 VAL 221 411 411 VAL VAL B . n B 1 222 GLY 222 412 412 GLY GLY B . n B 1 223 GLU 223 413 413 GLU GLU B . n B 1 224 GLU 224 414 414 GLU GLU B . n B 1 225 CYS 225 415 415 CYS CYS B . n B 1 226 ASP 226 416 416 ASP ASP B . n B 1 227 CYS 227 417 417 CYS CYS B . n B 1 228 GLY 228 418 418 GLY GLY B . n B 1 229 THR 229 419 419 THR THR B . n B 1 230 PRO 230 420 420 PRO PRO B . n B 1 231 GLU 231 421 421 GLU GLU B . n B 1 232 ASN 232 422 422 ASN ASN B . n B 1 233 CYS 233 423 423 CYS CYS B . n B 1 234 GLN 234 424 424 GLN GLN B . n B 1 235 ASN 235 425 425 ASN ASN B . n B 1 236 GLU 236 426 426 GLU GLU B . n B 1 237 CYS 237 427 427 CYS CYS B . n B 1 238 CYS 238 428 428 CYS CYS B . n B 1 239 ASP 239 429 429 ASP ASP B . n B 1 240 ALA 240 430 430 ALA ALA B . n B 1 241 ALA 241 431 431 ALA ALA B . n B 1 242 THR 242 432 432 THR THR B . n B 1 243 CYS 243 433 433 CYS CYS B . n B 1 244 LYS 244 434 434 LYS LYS B . n B 1 245 LEU 245 435 435 LEU LEU B . n B 1 246 LYS 246 436 436 LYS LYS B . n B 1 247 SER 247 437 437 SER SER B . n B 1 248 GLY 248 438 438 GLY GLY B . n B 1 249 SER 249 439 439 SER SER B . n B 1 250 GLN 250 440 440 GLN GLN B . n B 1 251 CYS 251 441 441 CYS CYS B . n B 1 252 GLY 252 442 442 GLY GLY B . n B 1 253 HIS 253 443 443 HIS HIS B . n B 1 254 GLY 254 444 444 GLY GLY B . n B 1 255 ASP 255 445 445 ASP ASP B . n B 1 256 CYS 256 446 446 CYS CYS B . n B 1 257 CYS 257 447 447 CYS CYS B . n B 1 258 GLU 258 448 448 GLU GLU B . n B 1 259 GLN 259 449 449 GLN GLN B . n B 1 260 CYS 260 450 450 CYS CYS B . n B 1 261 LYS 261 451 451 LYS LYS B . n B 1 262 PHE 262 452 452 PHE PHE B . n B 1 263 SER 263 453 453 SER SER B . n B 1 264 LYS 264 454 454 LYS LYS B . n B 1 265 SER 265 455 455 SER SER B . n B 1 266 GLY 266 456 456 GLY GLY B . n B 1 267 THR 267 457 457 THR THR B . n B 1 268 GLU 268 458 458 GLU GLU B . n B 1 269 CYS 269 459 459 CYS CYS B . n B 1 270 ARG 270 460 460 ARG ARG B . n B 1 271 ALA 271 461 461 ALA ALA B . n B 1 272 SER 272 462 462 SER SER B . n B 1 273 MET 273 463 463 MET MET B . n B 1 274 SER 274 464 464 SER SER B . n B 1 275 GLU 275 465 465 GLU GLU B . n B 1 276 CYS 276 466 466 CYS CYS B . n B 1 277 ASP 277 467 467 ASP ASP B . n B 1 278 PRO 278 468 468 PRO PRO B . n B 1 279 ALA 279 469 469 ALA ALA B . n B 1 280 GLU 280 470 470 GLU GLU B . n B 1 281 HIS 281 471 471 HIS HIS B . n B 1 282 CYS 282 472 472 CYS CYS B . n B 1 283 THR 283 473 473 THR THR B . n B 1 284 GLY 284 474 474 GLY GLY B . n B 1 285 GLN 285 475 475 GLN GLN B . n B 1 286 SER 286 476 476 SER SER B . n B 1 287 SER 287 477 477 SER SER B . n B 1 288 GLU 288 478 478 GLU GLU B . n B 1 289 CYS 289 479 479 CYS CYS B . n B 1 290 PRO 290 480 480 PRO PRO B . n B 1 291 ALA 291 481 481 ALA ALA B . n B 1 292 ASP 292 482 482 ASP ASP B . n B 1 293 VAL 293 483 483 VAL VAL B . n B 1 294 PHE 294 484 484 PHE PHE B . n B 1 295 HIS 295 485 485 HIS HIS B . n B 1 296 LYS 296 486 486 LYS LYS B . n B 1 297 ASN 297 487 487 ASN ASN B . n B 1 298 GLY 298 488 488 GLY GLY B . n B 1 299 GLN 299 489 489 GLN GLN B . n B 1 300 PRO 300 490 490 PRO PRO B . n B 1 301 CYS 301 491 491 CYS CYS B . n B 1 302 LEU 302 492 492 LEU LEU B . n B 1 303 ASP 303 493 493 ASP ASP B . n B 1 304 ASN 304 494 494 ASN ASN B . n B 1 305 TYR 305 495 495 TYR TYR B . n B 1 306 GLY 306 496 496 GLY GLY B . n B 1 307 TYR 307 497 497 TYR TYR B . n B 1 308 CYS 308 498 498 CYS CYS B . n B 1 309 TYR 309 499 499 TYR TYR B . n B 1 310 ASN 310 500 500 ASN ASN B . n B 1 311 GLY 311 501 501 GLY GLY B . n B 1 312 ASN 312 502 502 ASN ASN B . n B 1 313 CYS 313 503 503 CYS CYS B . n B 1 314 PRO 314 504 504 PRO PRO B . n B 1 315 ILE 315 505 505 ILE ILE B . n B 1 316 MET 316 506 506 MET MET B . n B 1 317 TYR 317 507 507 TYR TYR B . n B 1 318 HIS 318 508 508 HIS HIS B . n B 1 319 GLN 319 509 509 GLN GLN B . n B 1 320 CYS 320 510 510 CYS CYS B . n B 1 321 TYR 321 511 511 TYR TYR B . n B 1 322 ASP 322 512 512 ASP ASP B . n B 1 323 LEU 323 513 513 LEU LEU B . n B 1 324 PHE 324 514 514 PHE PHE B . n B 1 325 GLY 325 515 515 GLY GLY B . n B 1 326 ALA 326 516 516 ALA ALA B . n B 1 327 ASP 327 517 517 ASP ASP B . n B 1 328 VAL 328 518 518 VAL VAL B . n B 1 329 TYR 329 519 519 TYR TYR B . n B 1 330 GLU 330 520 520 GLU GLU B . n B 1 331 ALA 331 521 521 ALA ALA B . n B 1 332 GLU 332 522 522 GLU GLU B . n B 1 333 ASP 333 523 523 ASP ASP B . n B 1 334 SER 334 524 524 SER SER B . n B 1 335 CYS 335 525 525 CYS CYS B . n B 1 336 PHE 336 526 526 PHE PHE B . n B 1 337 GLU 337 527 527 GLU GLU B . n B 1 338 ARG 338 528 528 ARG ARG B . n B 1 339 ASN 339 529 529 ASN ASN B . n B 1 340 GLN 340 530 530 GLN GLN B . n B 1 341 LYS 341 531 531 LYS LYS B . n B 1 342 GLY 342 532 532 GLY GLY B . n B 1 343 ASN 343 533 533 ASN ASN B . n B 1 344 TYR 344 534 534 TYR TYR B . n B 1 345 TYR 345 535 535 TYR TYR B . n B 1 346 GLY 346 536 536 GLY GLY B . n B 1 347 TYR 347 537 537 TYR TYR B . n B 1 348 CYS 348 538 538 CYS CYS B . n B 1 349 ARG 349 539 539 ARG ARG B . n B 1 350 LYS 350 540 540 LYS LYS B . n B 1 351 GLU 351 541 541 GLU GLU B . n B 1 352 ASN 352 542 542 ASN ASN B . n B 1 353 GLY 353 543 543 GLY GLY B . n B 1 354 ASN 354 544 544 ASN ASN B . n B 1 355 LYS 355 545 545 LYS LYS B . n B 1 356 ILE 356 546 546 ILE ILE B . n B 1 357 PRO 357 547 547 PRO PRO B . n B 1 358 CYS 358 548 548 CYS CYS B . n B 1 359 ALA 359 549 549 ALA ALA B . n B 1 360 PRO 360 550 550 PRO PRO B . n B 1 361 GLU 361 551 551 GLU GLU B . n B 1 362 ASP 362 552 552 ASP ASP B . n B 1 363 VAL 363 553 553 VAL VAL B . n B 1 364 LYS 364 554 554 LYS LYS B . n B 1 365 CYS 365 555 555 CYS CYS B . n B 1 366 GLY 366 556 556 GLY GLY B . n B 1 367 ARG 367 557 557 ARG ARG B . n B 1 368 LEU 368 558 558 LEU LEU B . n B 1 369 TYR 369 559 559 TYR TYR B . n B 1 370 CYS 370 560 560 CYS CYS B . n B 1 371 LYS 371 561 561 LYS LYS B . n B 1 372 ASP 372 562 562 ASP ASP B . n B 1 373 ASN 373 563 563 ASN ASN B . n B 1 374 SER 374 564 564 SER SER B . n B 1 375 PRO 375 565 565 PRO PRO B . n B 1 376 GLY 376 566 566 GLY GLY B . n B 1 377 GLN 377 567 567 GLN GLN B . n B 1 378 ASN 378 568 568 ASN ASN B . n B 1 379 ASN 379 569 569 ASN ASN B . n B 1 380 PRO 380 570 570 PRO PRO B . n B 1 381 CYS 381 571 571 CYS CYS B . n B 1 382 LYS 382 572 572 LYS LYS B . n B 1 383 MET 383 573 573 MET MET B . n B 1 384 PHE 384 574 574 PHE PHE B . n B 1 385 TYR 385 575 575 TYR TYR B . n B 1 386 SER 386 576 576 SER SER B . n B 1 387 ASN 387 577 577 ASN ASN B . n B 1 388 GLU 388 578 578 GLU GLU B . n B 1 389 ASP 389 579 579 ASP ASP B . n B 1 390 GLU 390 580 580 GLU GLU B . n B 1 391 HIS 391 581 581 HIS HIS B . n B 1 392 LYS 392 582 582 LYS LYS B . n B 1 393 GLY 393 583 583 GLY GLY B . n B 1 394 MET 394 584 584 MET MET B . n B 1 395 VAL 395 585 585 VAL VAL B . n B 1 396 LEU 396 586 586 LEU LEU B . n B 1 397 PRO 397 587 587 PRO PRO B . n B 1 398 GLY 398 588 588 GLY GLY B . n B 1 399 THR 399 589 589 THR THR B . n B 1 400 LYS 400 590 590 LYS LYS B . n B 1 401 CYS 401 591 591 CYS CYS B . n B 1 402 ALA 402 592 592 ALA ALA B . n B 1 403 ASP 403 593 593 ASP ASP B . n B 1 404 GLY 404 594 594 GLY GLY B . n B 1 405 LYS 405 595 595 LYS LYS B . n B 1 406 VAL 406 596 596 VAL VAL B . n B 1 407 CYS 407 597 597 CYS CYS B . n B 1 408 SER 408 598 598 SER SER B . n B 1 409 ASN 409 599 599 ASN ASN B . n B 1 410 GLY 410 600 600 GLY GLY B . n B 1 411 HIS 411 601 601 HIS HIS B . n B 1 412 CYS 412 602 602 CYS CYS B . n B 1 413 VAL 413 603 603 VAL VAL B . n B 1 414 ASP 414 604 604 ASP ASP B . n B 1 415 VAL 415 605 605 VAL VAL B . n B 1 416 ALA 416 606 606 ALA ALA B . n B 1 417 THR 417 607 607 THR THR B . n B 1 418 ALA 418 608 608 ALA ALA B . n B 1 419 TYR 419 609 609 TYR TYR B . n # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 181 A ASN 371 ? ASN 'GLYCOSYLATION SITE' 2 B ASN 181 B ASN 371 ? ASN 'GLYCOSYLATION SITE' # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_defined_assembly ? monomeric 1 2 author_defined_assembly ? monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,C,D,E,F,G,H,I,J,K,L,M,N,O,CA 2 1 B,P,Q,R,S,T,U,V,W,X,Y,Z,AA,BA,DA # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 NE2 ? A HIS 143 ? A HIS 333 ? 1_555 ZN ? L ZN . ? A ZN 700 ? 1_555 NE2 ? A HIS 147 ? A HIS 337 ? 1_555 97.0 ? 2 NE2 ? A HIS 143 ? A HIS 333 ? 1_555 ZN ? L ZN . ? A ZN 700 ? 1_555 NE2 ? A HIS 153 ? A HIS 343 ? 1_555 100.5 ? 3 NE2 ? A HIS 147 ? A HIS 337 ? 1_555 ZN ? L ZN . ? A ZN 700 ? 1_555 NE2 ? A HIS 153 ? A HIS 343 ? 1_555 106.2 ? 4 NE2 ? A HIS 143 ? A HIS 333 ? 1_555 ZN ? L ZN . ? A ZN 700 ? 1_555 O ? CA HOH . ? A HOH 153 ? 1_555 111.7 ? 5 NE2 ? A HIS 147 ? A HIS 337 ? 1_555 ZN ? L ZN . ? A ZN 700 ? 1_555 O ? CA HOH . ? A HOH 153 ? 1_555 108.6 ? 6 NE2 ? A HIS 153 ? A HIS 343 ? 1_555 ZN ? L ZN . ? A ZN 700 ? 1_555 O ? CA HOH . ? A HOH 153 ? 1_555 128.2 ? 7 NE2 ? B HIS 143 ? B HIS 333 ? 1_555 ZN ? Y ZN . ? B ZN 700 ? 1_555 NE2 ? B HIS 147 ? B HIS 337 ? 1_555 95.1 ? 8 NE2 ? B HIS 143 ? B HIS 333 ? 1_555 ZN ? Y ZN . ? B ZN 700 ? 1_555 NE2 ? B HIS 153 ? B HIS 343 ? 1_555 104.8 ? 9 NE2 ? B HIS 147 ? B HIS 337 ? 1_555 ZN ? Y ZN . ? B ZN 700 ? 1_555 NE2 ? B HIS 153 ? B HIS 343 ? 1_555 94.8 ? 10 NE2 ? B HIS 143 ? B HIS 333 ? 1_555 ZN ? Y ZN . ? B ZN 700 ? 1_555 O ? DA HOH . ? B HOH 155 ? 1_555 121.6 ? 11 NE2 ? B HIS 147 ? B HIS 337 ? 1_555 ZN ? Y ZN . ? B ZN 700 ? 1_555 O ? DA HOH . ? B HOH 155 ? 1_555 115.8 ? 12 NE2 ? B HIS 153 ? B HIS 343 ? 1_555 ZN ? Y ZN . ? B ZN 700 ? 1_555 O ? DA HOH . ? B HOH 155 ? 1_555 119.3 ? 13 OE1 ? A GLU 11 ? A GLU 201 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 OD1 ? A ASP 95 ? A ASP 285 ? 1_555 87.0 ? 14 OE1 ? A GLU 11 ? A GLU 201 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 OD2 ? A ASP 95 ? A ASP 285 ? 1_555 79.9 ? 15 OD1 ? A ASP 95 ? A ASP 285 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 OD2 ? A ASP 95 ? A ASP 285 ? 1_555 51.4 ? 16 OE1 ? A GLU 11 ? A GLU 201 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? A CYS 198 ? A CYS 388 ? 1_555 158.9 ? 17 OD1 ? A ASP 95 ? A ASP 285 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? A CYS 198 ? A CYS 388 ? 1_555 84.2 ? 18 OD2 ? A ASP 95 ? A ASP 285 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? A CYS 198 ? A CYS 388 ? 1_555 79.6 ? 19 OE1 ? A GLU 11 ? A GLU 201 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 ND2 ? A ASN 201 ? A ASN 391 ? 1_555 121.6 ? 20 OD1 ? A ASP 95 ? A ASP 285 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 ND2 ? A ASN 201 ? A ASN 391 ? 1_555 148.3 ? 21 OD2 ? A ASP 95 ? A ASP 285 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 ND2 ? A ASN 201 ? A ASN 391 ? 1_555 139.8 ? 22 O ? A CYS 198 ? A CYS 388 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 ND2 ? A ASN 201 ? A ASN 391 ? 1_555 72.9 ? 23 OE1 ? A GLU 11 ? A GLU 201 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? CA HOH . ? A HOH 86 ? 1_555 88.1 ? 24 OD1 ? A ASP 95 ? A ASP 285 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? CA HOH . ? A HOH 86 ? 1_555 130.8 ? 25 OD2 ? A ASP 95 ? A ASP 285 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? CA HOH . ? A HOH 86 ? 1_555 79.5 ? 26 O ? A CYS 198 ? A CYS 388 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? CA HOH . ? A HOH 86 ? 1_555 83.2 ? 27 ND2 ? A ASN 201 ? A ASN 391 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? CA HOH . ? A HOH 86 ? 1_555 68.8 ? 28 OE1 ? A GLU 11 ? A GLU 201 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? CA HOH . ? A HOH 4 ? 1_555 97.3 ? 29 OD1 ? A ASP 95 ? A ASP 285 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? CA HOH . ? A HOH 4 ? 1_555 80.1 ? 30 OD2 ? A ASP 95 ? A ASP 285 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? CA HOH . ? A HOH 4 ? 1_555 131.4 ? 31 O ? A CYS 198 ? A CYS 388 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? CA HOH . ? A HOH 4 ? 1_555 100.0 ? 32 ND2 ? A ASN 201 ? A ASN 391 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? CA HOH . ? A HOH 4 ? 1_555 82.7 ? 33 O ? CA HOH . ? A HOH 86 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 O ? CA HOH . ? A HOH 4 ? 1_555 149.1 ? 34 OE1 ? A GLU 11 ? A GLU 201 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 OD1 ? A ASN 201 ? A ASN 391 ? 1_555 73.0 ? 35 OD1 ? A ASP 95 ? A ASP 285 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 OD1 ? A ASN 201 ? A ASN 391 ? 1_555 144.0 ? 36 OD2 ? A ASP 95 ? A ASP 285 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 OD1 ? A ASN 201 ? A ASN 391 ? 1_555 145.9 ? 37 O ? A CYS 198 ? A CYS 388 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 OD1 ? A ASN 201 ? A ASN 391 ? 1_555 123.7 ? 38 ND2 ? A ASN 201 ? A ASN 391 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 OD1 ? A ASN 201 ? A ASN 391 ? 1_555 50.9 ? 39 O ? CA HOH . ? A HOH 86 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 OD1 ? A ASN 201 ? A ASN 391 ? 1_555 79.3 ? 40 O ? CA HOH . ? A HOH 4 ? 1_555 CA ? M CA . ? A CA 701 ? 1_555 OD1 ? A ASN 201 ? A ASN 391 ? 1_555 73.3 ? 41 O ? A VAL 213 ? A VAL 403 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OD1 ? A ASN 216 ? A ASN 406 ? 1_555 81.8 ? 42 O ? A VAL 213 ? A VAL 403 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OE1 ? A GLU 220 ? A GLU 410 ? 1_555 78.1 ? 43 OD1 ? A ASN 216 ? A ASN 406 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OE1 ? A GLU 220 ? A GLU 410 ? 1_555 97.4 ? 44 O ? A VAL 213 ? A VAL 403 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 O ? A LEU 218 ? A LEU 408 ? 1_555 164.0 ? 45 OD1 ? A ASN 216 ? A ASN 406 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 O ? A LEU 218 ? A LEU 408 ? 1_555 84.9 ? 46 OE1 ? A GLU 220 ? A GLU 410 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 O ? A LEU 218 ? A LEU 408 ? 1_555 94.7 ? 47 O ? A VAL 213 ? A VAL 403 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OE1 ? A GLU 223 ? A GLU 413 ? 1_555 119.3 ? 48 OD1 ? A ASN 216 ? A ASN 406 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OE1 ? A GLU 223 ? A GLU 413 ? 1_555 154.2 ? 49 OE1 ? A GLU 220 ? A GLU 410 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OE1 ? A GLU 223 ? A GLU 413 ? 1_555 101.3 ? 50 O ? A LEU 218 ? A LEU 408 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OE1 ? A GLU 223 ? A GLU 413 ? 1_555 76.0 ? 51 O ? A VAL 213 ? A VAL 403 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OE2 ? A GLU 223 ? A GLU 413 ? 1_555 71.5 ? 52 OD1 ? A ASN 216 ? A ASN 406 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OE2 ? A GLU 223 ? A GLU 413 ? 1_555 149.3 ? 53 OE1 ? A GLU 220 ? A GLU 410 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OE2 ? A GLU 223 ? A GLU 413 ? 1_555 91.9 ? 54 O ? A LEU 218 ? A LEU 408 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OE2 ? A GLU 223 ? A GLU 413 ? 1_555 123.5 ? 55 OE1 ? A GLU 223 ? A GLU 413 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OE2 ? A GLU 223 ? A GLU 413 ? 1_555 47.7 ? 56 O ? A VAL 213 ? A VAL 403 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OD2 ? A ASP 226 ? A ASP 416 ? 1_555 83.3 ? 57 OD1 ? A ASN 216 ? A ASN 406 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OD2 ? A ASP 226 ? A ASP 416 ? 1_555 82.6 ? 58 OE1 ? A GLU 220 ? A GLU 410 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OD2 ? A ASP 226 ? A ASP 416 ? 1_555 161.2 ? 59 O ? A LEU 218 ? A LEU 408 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OD2 ? A ASP 226 ? A ASP 416 ? 1_555 104.0 ? 60 OE1 ? A GLU 223 ? A GLU 413 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OD2 ? A ASP 226 ? A ASP 416 ? 1_555 85.2 ? 61 OE2 ? A GLU 223 ? A GLU 413 ? 1_555 CA ? N CA . ? A CA 702 ? 1_555 OD2 ? A ASP 226 ? A ASP 416 ? 1_555 79.4 ? 62 OE1 ? A GLU 280 ? A GLU 470 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 O ? A PRO 278 ? A PRO 468 ? 1_555 80.2 ? 63 OE1 ? A GLU 280 ? A GLU 470 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 OD2 ? A ASP 292 ? A ASP 482 ? 1_555 94.4 ? 64 O ? A PRO 278 ? A PRO 468 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 OD2 ? A ASP 292 ? A ASP 482 ? 1_555 170.9 ? 65 OE1 ? A GLU 280 ? A GLU 470 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 OE2 ? A GLU 280 ? A GLU 470 ? 1_555 51.8 ? 66 O ? A PRO 278 ? A PRO 468 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 OE2 ? A GLU 280 ? A GLU 470 ? 1_555 90.4 ? 67 OD2 ? A ASP 292 ? A ASP 482 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 OE2 ? A GLU 280 ? A GLU 470 ? 1_555 92.0 ? 68 OE1 ? A GLU 280 ? A GLU 470 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 O ? A VAL 293 ? A VAL 483 ? 1_555 89.0 ? 69 O ? A PRO 278 ? A PRO 468 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 O ? A VAL 293 ? A VAL 483 ? 1_555 87.3 ? 70 OD2 ? A ASP 292 ? A ASP 482 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 O ? A VAL 293 ? A VAL 483 ? 1_555 85.3 ? 71 OE2 ? A GLU 280 ? A GLU 470 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 O ? A VAL 293 ? A VAL 483 ? 1_555 140.5 ? 72 OE1 ? A GLU 280 ? A GLU 470 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 OD2 ? A ASP 277 ? A ASP 467 ? 1_555 162.9 ? 73 O ? A PRO 278 ? A PRO 468 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 OD2 ? A ASP 277 ? A ASP 467 ? 1_555 89.9 ? 74 OD2 ? A ASP 292 ? A ASP 482 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 OD2 ? A ASP 277 ? A ASP 467 ? 1_555 93.5 ? 75 OE2 ? A GLU 280 ? A GLU 470 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 OD2 ? A ASP 277 ? A ASP 467 ? 1_555 142.9 ? 76 O ? A VAL 293 ? A VAL 483 ? 1_555 CA ? O CA . ? A CA 703 ? 1_555 OD2 ? A ASP 277 ? A ASP 467 ? 1_555 76.5 ? 77 OD2 ? B ASP 95 ? B ASP 285 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 OD1 ? B ASN 201 ? B ASN 391 ? 1_555 141.1 ? 78 OD2 ? B ASP 95 ? B ASP 285 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 OD1 ? B ASP 95 ? B ASP 285 ? 1_555 51.2 ? 79 OD1 ? B ASN 201 ? B ASN 391 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 OD1 ? B ASP 95 ? B ASP 285 ? 1_555 158.4 ? 80 OD2 ? B ASP 95 ? B ASP 285 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 OE1 ? B GLU 11 ? B GLU 201 ? 1_555 93.6 ? 81 OD1 ? B ASN 201 ? B ASN 391 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 OE1 ? B GLU 11 ? B GLU 201 ? 1_555 74.1 ? 82 OD1 ? B ASP 95 ? B ASP 285 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 OE1 ? B GLU 11 ? B GLU 201 ? 1_555 88.8 ? 83 OD2 ? B ASP 95 ? B ASP 285 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 O ? B CYS 198 ? B CYS 388 ? 1_555 74.1 ? 84 OD1 ? B ASN 201 ? B ASN 391 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 O ? B CYS 198 ? B CYS 388 ? 1_555 118.5 ? 85 OD1 ? B ASP 95 ? B ASP 285 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 O ? B CYS 198 ? B CYS 388 ? 1_555 79.7 ? 86 OE1 ? B GLU 11 ? B GLU 201 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 O ? B CYS 198 ? B CYS 388 ? 1_555 166.8 ? 87 OD2 ? B ASP 95 ? B ASP 285 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 ND2 ? B ASN 201 ? B ASN 391 ? 1_555 163.2 ? 88 OD1 ? B ASN 201 ? B ASN 391 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 ND2 ? B ASN 201 ? B ASN 391 ? 1_555 47.1 ? 89 OD1 ? B ASP 95 ? B ASP 285 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 ND2 ? B ASN 201 ? B ASN 391 ? 1_555 128.2 ? 90 OE1 ? B GLU 11 ? B GLU 201 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 ND2 ? B ASN 201 ? B ASN 391 ? 1_555 103.2 ? 91 O ? B CYS 198 ? B CYS 388 ? 1_555 CA ? Z CA . ? B CA 711 ? 1_555 ND2 ? B ASN 201 ? B ASN 391 ? 1_555 89.1 ? 92 O ? B LEU 218 ? B LEU 408 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OD2 ? B ASP 226 ? B ASP 416 ? 1_555 95.4 ? 93 O ? B LEU 218 ? B LEU 408 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OD1 ? B ASN 216 ? B ASN 406 ? 1_555 88.1 ? 94 OD2 ? B ASP 226 ? B ASP 416 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OD1 ? B ASN 216 ? B ASN 406 ? 1_555 80.8 ? 95 O ? B LEU 218 ? B LEU 408 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 O ? B VAL 213 ? B VAL 403 ? 1_555 159.6 ? 96 OD2 ? B ASP 226 ? B ASP 416 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 O ? B VAL 213 ? B VAL 403 ? 1_555 84.5 ? 97 OD1 ? B ASN 216 ? B ASN 406 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 O ? B VAL 213 ? B VAL 403 ? 1_555 71.7 ? 98 O ? B LEU 218 ? B LEU 408 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE1 ? B GLU 220 ? B GLU 410 ? 1_555 97.3 ? 99 OD2 ? B ASP 226 ? B ASP 416 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE1 ? B GLU 220 ? B GLU 410 ? 1_555 167.1 ? 100 OD1 ? B ASN 216 ? B ASN 406 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE1 ? B GLU 220 ? B GLU 410 ? 1_555 97.5 ? 101 O ? B VAL 213 ? B VAL 403 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE1 ? B GLU 220 ? B GLU 410 ? 1_555 82.9 ? 102 O ? B LEU 218 ? B LEU 408 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE1 ? B GLU 223 ? B GLU 413 ? 1_555 72.7 ? 103 OD2 ? B ASP 226 ? B ASP 416 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE1 ? B GLU 223 ? B GLU 413 ? 1_555 92.5 ? 104 OD1 ? B ASN 216 ? B ASN 406 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE1 ? B GLU 223 ? B GLU 413 ? 1_555 159.1 ? 105 O ? B VAL 213 ? B VAL 403 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE1 ? B GLU 223 ? B GLU 413 ? 1_555 127.7 ? 106 OE1 ? B GLU 220 ? B GLU 410 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE1 ? B GLU 223 ? B GLU 413 ? 1_555 93.3 ? 107 O ? B LEU 218 ? B LEU 408 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE2 ? B GLU 223 ? B GLU 413 ? 1_555 120.8 ? 108 OD2 ? B ASP 226 ? B ASP 416 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE2 ? B GLU 223 ? B GLU 413 ? 1_555 91.7 ? 109 OD1 ? B ASN 216 ? B ASN 406 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE2 ? B GLU 223 ? B GLU 413 ? 1_555 150.8 ? 110 O ? B VAL 213 ? B VAL 403 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE2 ? B GLU 223 ? B GLU 413 ? 1_555 79.6 ? 111 OE1 ? B GLU 220 ? B GLU 410 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE2 ? B GLU 223 ? B GLU 413 ? 1_555 83.6 ? 112 OE1 ? B GLU 223 ? B GLU 413 ? 1_555 CA ? AA CA . ? B CA 712 ? 1_555 OE2 ? B GLU 223 ? B GLU 413 ? 1_555 48.3 ? 113 O ? B VAL 293 ? B VAL 483 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OE2 ? B GLU 280 ? B GLU 470 ? 1_555 139.4 ? 114 O ? B VAL 293 ? B VAL 483 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 O ? B PRO 278 ? B PRO 468 ? 1_555 91.4 ? 115 OE2 ? B GLU 280 ? B GLU 470 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 O ? B PRO 278 ? B PRO 468 ? 1_555 84.3 ? 116 O ? B VAL 293 ? B VAL 483 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OD1 ? B ASP 292 ? B ASP 482 ? 1_555 92.5 ? 117 OE2 ? B GLU 280 ? B GLU 470 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OD1 ? B ASP 292 ? B ASP 482 ? 1_555 82.3 ? 118 O ? B PRO 278 ? B PRO 468 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OD1 ? B ASP 292 ? B ASP 482 ? 1_555 163.6 ? 119 O ? B VAL 293 ? B VAL 483 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OE1 ? B GLU 280 ? B GLU 470 ? 1_555 91.9 ? 120 OE2 ? B GLU 280 ? B GLU 470 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OE1 ? B GLU 280 ? B GLU 470 ? 1_555 47.7 ? 121 O ? B PRO 278 ? B PRO 468 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OE1 ? B GLU 280 ? B GLU 470 ? 1_555 89.0 ? 122 OD1 ? B ASP 292 ? B ASP 482 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OE1 ? B GLU 280 ? B GLU 470 ? 1_555 75.0 ? 123 O ? B VAL 293 ? B VAL 483 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OD2 ? B ASP 277 ? B ASP 467 ? 1_555 77.4 ? 124 OE2 ? B GLU 280 ? B GLU 470 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OD2 ? B ASP 277 ? B ASP 467 ? 1_555 143.3 ? 125 O ? B PRO 278 ? B PRO 468 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OD2 ? B ASP 277 ? B ASP 467 ? 1_555 96.8 ? 126 OD1 ? B ASP 292 ? B ASP 482 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OD2 ? B ASP 277 ? B ASP 467 ? 1_555 99.6 ? 127 OE1 ? B GLU 280 ? B GLU 470 ? 1_555 CA ? BA CA . ? B CA 713 ? 1_555 OD2 ? B ASP 277 ? B ASP 467 ? 1_555 167.9 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2007-07-10 2 'Structure model' 1 1 2008-04-30 3 'Structure model' 1 2 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Non-polymer description' 3 3 'Structure model' 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal ADSC 'data collection' Quantum ? 1 MOLREP phasing 'in CCP4' ? 2 CNS refinement 1.0 ? 3 HKL-2000 'data reduction' . ? 4 HKL-2000 'data scaling' . ? 5 # _pdbx_database_remark.id 999 _pdbx_database_remark.text ;SEQUENCE There is difference between the SEQRES and the sequence database. The depositors believe it is a variant. ; # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 277 ? ? -132.13 -69.86 2 1 ARG A 297 ? ? 65.55 -38.09 3 1 CYS A 308 ? ? 88.41 -20.53 4 1 SER A 313 ? ? -90.67 50.69 5 1 LEU A 339 ? ? -84.94 32.17 6 1 TYR A 347 ? ? -85.40 39.00 7 1 CYS A 350 ? ? -152.11 31.97 8 1 ASP A 352 ? ? -80.96 49.27 9 1 MET A 357 ? ? -94.63 38.62 10 1 ASN A 383 ? ? -69.22 -73.71 11 1 PRO A 386 ? ? -64.01 79.59 12 1 ASP A 429 ? ? -101.67 79.00 13 1 ALA A 430 ? ? -25.70 -56.01 14 1 ASP A 517 ? ? 58.47 18.19 15 1 ASN A 533 ? ? -85.00 -156.67 16 1 ASN A 542 ? ? 49.47 19.00 17 1 ASN A 563 ? ? -93.66 31.78 18 1 ASN A 568 ? ? 86.10 -33.66 19 1 CYS A 571 ? ? -117.20 53.45 20 1 ASN A 577 ? ? -61.40 0.87 21 1 ASP A 579 ? ? -165.66 86.22 22 1 ASN B 253 ? ? -90.85 -72.15 23 1 ASP B 277 ? ? -160.80 -80.28 24 1 ARG B 297 ? ? 64.98 -35.42 25 1 CYS B 308 ? ? 82.44 -11.85 26 1 CYS B 350 ? ? -149.91 32.27 27 1 ASP B 352 ? ? -83.56 44.46 28 1 ASN B 383 ? ? -62.90 -71.47 29 1 GLU B 387 ? ? -29.63 -49.76 30 1 ALA B 430 ? ? -33.70 -32.06 31 1 ALA B 481 ? ? -41.21 150.92 32 1 GLN B 489 ? ? -57.97 107.12 33 1 ASN B 500 ? ? 39.72 45.33 34 1 CYS B 503 ? ? -118.92 77.99 35 1 ASN B 529 ? ? -56.14 -3.70 36 1 ASN B 533 ? ? -90.50 -155.79 37 1 ASP B 579 ? ? -157.06 89.66 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A HIS 191 ? A HIS 1 2 1 Y 1 A GLN 192 ? A GLN 2 3 1 Y 1 A LYS 193 ? A LYS 3 4 1 Y 1 A TYR 194 ? A TYR 4 5 1 Y 1 B HIS 191 ? B HIS 1 6 1 Y 1 B GLN 192 ? B GLN 2 7 1 Y 1 B LYS 193 ? B LYS 3 8 1 Y 1 B TYR 194 ? B TYR 4 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 BETA-D-MANNOSE BMA 4 ALPHA-D-MANNOSE MAN 5 ALPHA-L-FUCOSE FUC 6 'ZINC ION' ZN 7 'CALCIUM ION' CA 8 water HOH # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 NAG 1 801 801 NAG NAG A . D 2 NAG 2 802 802 NAG NAG A . E 3 BMA 3 803 803 BMA BMA A . F 2 NAG 4 804 804 NAG NAG A . G 4 MAN 5 805 805 MAN MAN A . H 2 NAG 6 806 806 NAG NAG A . I 4 MAN 7 807 807 MAN MAN A . J 2 NAG 8 808 808 NAG NAG A . K 5 FUC 9 809 809 FUC FUC A . L 6 ZN 1 700 700 ZN ZN A . M 7 CA 1 701 701 CA CA A . N 7 CA 1 702 702 CA CA A . O 7 CA 1 703 703 CA CA A . P 2 NAG 1 801 801 NAG NAG B . Q 2 NAG 2 802 802 NAG NAG B . R 3 BMA 3 803 803 BMA BMA B . S 2 NAG 4 804 804 NAG NAG B . T 4 MAN 5 805 805 MAN MAN B . U 2 NAG 6 806 806 NAG NAG B . V 4 MAN 7 807 807 MAN MAN B . W 2 NAG 8 808 808 NAG NAG B . X 5 FUC 9 809 809 FUC FUC B . Y 6 ZN 1 700 700 ZN ZN B . Z 7 CA 1 711 711 CA CA B . AA 7 CA 1 712 712 CA CA B . BA 7 CA 1 713 713 CA CA B . CA 8 HOH 1 1 1 HOH TIP A . CA 8 HOH 2 2 2 HOH TIP A . CA 8 HOH 3 3 3 HOH TIP A . CA 8 HOH 4 4 4 HOH TIP A . CA 8 HOH 5 6 6 HOH TIP A . CA 8 HOH 6 7 7 HOH TIP A . CA 8 HOH 7 8 8 HOH TIP A . CA 8 HOH 8 10 10 HOH TIP A . CA 8 HOH 9 13 13 HOH TIP A . CA 8 HOH 10 16 16 HOH TIP A . CA 8 HOH 11 17 17 HOH TIP A . CA 8 HOH 12 19 19 HOH TIP A . CA 8 HOH 13 21 21 HOH TIP A . CA 8 HOH 14 22 22 HOH TIP A . CA 8 HOH 15 26 26 HOH TIP A . CA 8 HOH 16 28 28 HOH TIP A . CA 8 HOH 17 31 31 HOH TIP A . CA 8 HOH 18 33 33 HOH TIP A . CA 8 HOH 19 35 35 HOH TIP A . CA 8 HOH 20 38 38 HOH TIP A . CA 8 HOH 21 39 39 HOH TIP A . CA 8 HOH 22 40 40 HOH TIP A . CA 8 HOH 23 43 43 HOH TIP A . CA 8 HOH 24 45 45 HOH TIP A . CA 8 HOH 25 46 46 HOH TIP A . CA 8 HOH 26 47 47 HOH TIP A . CA 8 HOH 27 49 49 HOH TIP A . CA 8 HOH 28 50 50 HOH TIP A . CA 8 HOH 29 51 51 HOH TIP A . CA 8 HOH 30 54 54 HOH TIP A . CA 8 HOH 31 55 55 HOH TIP A . CA 8 HOH 32 56 56 HOH TIP A . CA 8 HOH 33 60 60 HOH TIP A . CA 8 HOH 34 63 63 HOH TIP A . CA 8 HOH 35 64 64 HOH TIP A . CA 8 HOH 36 67 67 HOH TIP A . CA 8 HOH 37 68 68 HOH TIP A . CA 8 HOH 38 69 69 HOH TIP A . CA 8 HOH 39 72 72 HOH TIP A . CA 8 HOH 40 74 74 HOH TIP A . CA 8 HOH 41 75 75 HOH TIP A . CA 8 HOH 42 76 76 HOH TIP A . CA 8 HOH 43 79 79 HOH TIP A . CA 8 HOH 44 80 80 HOH TIP A . CA 8 HOH 45 82 82 HOH TIP A . CA 8 HOH 46 83 83 HOH TIP A . CA 8 HOH 47 84 84 HOH TIP A . CA 8 HOH 48 86 86 HOH TIP A . CA 8 HOH 49 89 89 HOH TIP A . CA 8 HOH 50 90 90 HOH TIP A . CA 8 HOH 51 91 91 HOH TIP A . CA 8 HOH 52 93 93 HOH TIP A . CA 8 HOH 53 94 94 HOH TIP A . CA 8 HOH 54 95 95 HOH TIP A . CA 8 HOH 55 96 96 HOH TIP A . CA 8 HOH 56 97 97 HOH TIP A . CA 8 HOH 57 98 98 HOH TIP A . CA 8 HOH 58 100 100 HOH TIP A . CA 8 HOH 59 101 101 HOH TIP A . CA 8 HOH 60 102 102 HOH TIP A . CA 8 HOH 61 103 103 HOH TIP A . CA 8 HOH 62 104 104 HOH TIP A . CA 8 HOH 63 106 106 HOH TIP A . CA 8 HOH 64 107 107 HOH TIP A . CA 8 HOH 65 113 113 HOH TIP A . CA 8 HOH 66 116 116 HOH TIP A . CA 8 HOH 67 118 118 HOH TIP A . CA 8 HOH 68 119 119 HOH TIP A . CA 8 HOH 69 120 120 HOH TIP A . CA 8 HOH 70 122 122 HOH TIP A . CA 8 HOH 71 128 128 HOH TIP A . CA 8 HOH 72 131 131 HOH TIP A . CA 8 HOH 73 133 133 HOH TIP A . CA 8 HOH 74 137 137 HOH TIP A . CA 8 HOH 75 139 139 HOH TIP A . CA 8 HOH 76 140 140 HOH TIP A . CA 8 HOH 77 142 142 HOH TIP A . CA 8 HOH 78 145 145 HOH TIP A . CA 8 HOH 79 146 146 HOH TIP A . CA 8 HOH 80 147 147 HOH TIP A . CA 8 HOH 81 150 150 HOH TIP A . CA 8 HOH 82 151 151 HOH TIP A . CA 8 HOH 83 152 152 HOH TIP A . CA 8 HOH 84 153 153 HOH TIP A . CA 8 HOH 85 154 154 HOH TIP A . DA 8 HOH 1 5 5 HOH TIP B . DA 8 HOH 2 9 9 HOH TIP B . DA 8 HOH 3 11 11 HOH TIP B . DA 8 HOH 4 12 12 HOH TIP B . DA 8 HOH 5 14 14 HOH TIP B . DA 8 HOH 6 15 15 HOH TIP B . DA 8 HOH 7 18 18 HOH TIP B . DA 8 HOH 8 20 20 HOH TIP B . DA 8 HOH 9 23 23 HOH TIP B . DA 8 HOH 10 24 24 HOH TIP B . DA 8 HOH 11 27 27 HOH TIP B . DA 8 HOH 12 29 29 HOH TIP B . DA 8 HOH 13 30 30 HOH TIP B . DA 8 HOH 14 34 34 HOH TIP B . DA 8 HOH 15 36 36 HOH TIP B . DA 8 HOH 16 37 37 HOH TIP B . DA 8 HOH 17 41 41 HOH TIP B . DA 8 HOH 18 42 42 HOH TIP B . DA 8 HOH 19 44 44 HOH TIP B . DA 8 HOH 20 48 48 HOH TIP B . DA 8 HOH 21 52 52 HOH TIP B . DA 8 HOH 22 53 53 HOH TIP B . DA 8 HOH 23 57 57 HOH TIP B . DA 8 HOH 24 58 58 HOH TIP B . DA 8 HOH 25 59 59 HOH TIP B . DA 8 HOH 26 61 61 HOH TIP B . DA 8 HOH 27 62 62 HOH TIP B . DA 8 HOH 28 65 65 HOH TIP B . DA 8 HOH 29 66 66 HOH TIP B . DA 8 HOH 30 70 70 HOH TIP B . DA 8 HOH 31 71 71 HOH TIP B . DA 8 HOH 32 73 73 HOH TIP B . DA 8 HOH 33 77 77 HOH TIP B . DA 8 HOH 34 78 78 HOH TIP B . DA 8 HOH 35 81 81 HOH TIP B . DA 8 HOH 36 85 85 HOH TIP B . DA 8 HOH 37 87 87 HOH TIP B . DA 8 HOH 38 88 88 HOH TIP B . DA 8 HOH 39 92 92 HOH TIP B . DA 8 HOH 40 99 99 HOH TIP B . DA 8 HOH 41 105 105 HOH TIP B . DA 8 HOH 42 108 108 HOH TIP B . DA 8 HOH 43 110 110 HOH TIP B . DA 8 HOH 44 111 111 HOH TIP B . DA 8 HOH 45 112 112 HOH TIP B . DA 8 HOH 46 114 114 HOH TIP B . DA 8 HOH 47 115 115 HOH TIP B . DA 8 HOH 48 117 117 HOH TIP B . DA 8 HOH 49 121 121 HOH TIP B . DA 8 HOH 50 123 123 HOH TIP B . DA 8 HOH 51 124 124 HOH TIP B . DA 8 HOH 52 125 125 HOH TIP B . DA 8 HOH 53 126 126 HOH TIP B . DA 8 HOH 54 127 127 HOH TIP B . DA 8 HOH 55 129 129 HOH TIP B . DA 8 HOH 56 130 130 HOH TIP B . DA 8 HOH 57 132 132 HOH TIP B . DA 8 HOH 58 134 134 HOH TIP B . DA 8 HOH 59 135 135 HOH TIP B . DA 8 HOH 60 136 136 HOH TIP B . DA 8 HOH 61 141 141 HOH TIP B . DA 8 HOH 62 143 143 HOH TIP B . DA 8 HOH 63 144 144 HOH TIP B . DA 8 HOH 64 148 148 HOH TIP B . DA 8 HOH 65 149 149 HOH TIP B . DA 8 HOH 66 155 155 HOH TIP B . #