data_1NCD # _entry.id 1NCD # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 1NCD WWPDB D_1000175227 # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 1NCD _pdbx_database_status.recvd_initial_deposition_date 1992-01-21 _pdbx_database_status.deposit_site ? _pdbx_database_status.process_site ? _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Tulip, W.R.' 1 'Varghese, J.N.' 2 'Colman, P.M.' 3 # loop_ _citation.id _citation.title _citation.journal_abbrev _citation.journal_volume _citation.page_first _citation.page_last _citation.year _citation.journal_id_ASTM _citation.country _citation.journal_id_ISSN _citation.journal_id_CSD _citation.book_publisher _citation.pdbx_database_id_PubMed _citation.pdbx_database_id_DOI primary 'Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex.' J.Mol.Biol. 227 122 148 1992 JMOBAK UK 0022-2836 0070 ? 1381757 '10.1016/0022-2836(92)90687-F' 1 'Crystal Structures of Two Mutant Neuraminidase-Antibody Complexes with Amino Acid Substitutions in the Interface' J.Mol.Biol. 227 149 ? 1992 JMOBAK UK 0022-2836 0070 ? ? ? 2 'Crystal Structures of Neuraminidase-Antibody Complexes' 'Cold Spring Harbor Symp.Quant.Biol.' 54 257 ? 1989 CSHSAZ US 0091-7451 0421 ? ? ? 3 'Three-Dimensional Structure of a Complex of Antibody with Influenza Virus Neuraminidase' Nature 326 358 ? 1987 NATUAS UK 0028-0836 0006 ? ? ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Tulip, W.R.' 1 primary 'Varghese, J.N.' 2 primary 'Laver, W.G.' 3 primary 'Webster, R.G.' 4 primary 'Colman, P.M.' 5 1 'Tulip, W.R.' 6 1 'Varghese, J.N.' 7 1 'Webster, R.G.' 8 1 'Laver, W.G.' 9 1 'Colman, P.M.' 10 2 'Tulip, W.R.' 11 2 'Varghese, J.N.' 12 2 'Webster, R.G.' 13 2 'Air, G.M.' 14 2 'Laver, W.G.' 15 2 'Colman, P.M.' 16 3 'Colman, P.M.' 17 3 'Laver, W.G.' 18 3 'Varghese, J.N.' 19 3 'Baker, A.T.' 20 3 'Tulloch, P.A.' 21 3 'Air, G.M.' 22 3 'Webster, R.G.' 23 # _cell.entry_id 1NCD _cell.length_a 167.000 _cell.length_b 167.000 _cell.length_c 124.000 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? # _symmetry.entry_id 1NCD _symmetry.space_group_name_H-M 'P 4 21 2' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 90 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer nat 'INFLUENZA A SUBTYPE N9 NEURAMINIDASE' 43753.691 1 3.2.1.18 ? ? ? 2 polymer nat 'IGG2A-KAPPA NC41 FAB (LIGHT CHAIN)' 23722.311 1 ? ? ? ? 3 polymer nat 'IGG2A-KAPPA NC41 FAB (HEAVY CHAIN)' 23668.354 1 ? ? ? ? 4 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 5 ? ? ? ? 5 non-polymer man BETA-D-MANNOSE 180.156 1 ? ? ? ? 6 non-polymer man ALPHA-D-MANNOSE 180.156 3 ? ? ? ? 7 non-polymer syn 'CALCIUM ION' 40.078 1 ? ? ? ? 8 water nat water 18.015 69 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;IREFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRDLIS WPLSSPPTVYNSRVECIGWSSTSCHDGRARMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCQNGVCPV VFTDGSATGPAETRIYYFKEGKILKWEPLTGTAKHIEECSCYGEQAGVTCTCRDNWQGSNRPVIQIDPVAMTHTSQYICS PVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGGNTWLGRTISIASRSGYEMLKVPNALTDDRSKPTQGQTIVLNT DWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL ; ;IREFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRDLIS WPLSSPPTVYNSRVECIGWSSTSCHDGRARMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCQNGVCPV VFTDGSATGPAETRIYYFKEGKILKWEPLTGTAKHIEECSCYGEQAGVTCTCRDNWQGSNRPVIQIDPVAMTHTSQYICS PVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGGNTWLGRTISIASRSGYEMLKVPNALTDDRSKPTQGQTIVLNT DWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL ; N ? 2 'polypeptide(L)' no no ;DIVMTQSPKFMSTSVGDRVTITCKASQDVSTAVVWYQQKPGQSPKLLIYWASTRHIGVPDRFAGSGSGTDYTLTISSVQA EDLALYYCQQHYSPPWTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC ; ;DIVMTQSPKFMSTSVGDRVTITCKASQDVSTAVVWYQQKPGQSPKLLIYWASTRHIGVPDRFAGSGSGTDYTLTISSVQA EDLALYYCQQHYSPPWTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC ; L ? 3 'polypeptide(L)' no no ;QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLEWMGWINTNTGEPTYGEEFKGRFAFSLETSASTAN LQINNLKNEDKATFFCARGEDNFGSLSDYWGQGTTLTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLT WNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRG ; ;QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLEWMGWINTNTGEPTYGEEFKGRFAFSLETSASTAN LQINNLKNEDKATFFCARGEDNFGSLSDYWGQGTTLTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLT WNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRG ; H ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ILE n 1 2 ARG n 1 3 GLU n 1 4 PHE n 1 5 ASN n 1 6 ASN n 1 7 LEU n 1 8 THR n 1 9 LYS n 1 10 GLY n 1 11 LEU n 1 12 CYS n 1 13 THR n 1 14 ILE n 1 15 ASN n 1 16 SER n 1 17 TRP n 1 18 HIS n 1 19 ILE n 1 20 TYR n 1 21 GLY n 1 22 LYS n 1 23 ASP n 1 24 ASN n 1 25 ALA n 1 26 VAL n 1 27 ARG n 1 28 ILE n 1 29 GLY n 1 30 GLU n 1 31 ASP n 1 32 SER n 1 33 ASP n 1 34 VAL n 1 35 LEU n 1 36 VAL n 1 37 THR n 1 38 ARG n 1 39 GLU n 1 40 PRO n 1 41 TYR n 1 42 VAL n 1 43 SER n 1 44 CYS n 1 45 ASP n 1 46 PRO n 1 47 ASP n 1 48 GLU n 1 49 CYS n 1 50 ARG n 1 51 PHE n 1 52 TYR n 1 53 ALA n 1 54 LEU n 1 55 SER n 1 56 GLN n 1 57 GLY n 1 58 THR n 1 59 THR n 1 60 ILE n 1 61 ARG n 1 62 GLY n 1 63 LYS n 1 64 HIS n 1 65 SER n 1 66 ASN n 1 67 GLY n 1 68 THR n 1 69 ILE n 1 70 HIS n 1 71 ASP n 1 72 ARG n 1 73 SER n 1 74 GLN n 1 75 TYR n 1 76 ARG n 1 77 ASP n 1 78 LEU n 1 79 ILE n 1 80 SER n 1 81 TRP n 1 82 PRO n 1 83 LEU n 1 84 SER n 1 85 SER n 1 86 PRO n 1 87 PRO n 1 88 THR n 1 89 VAL n 1 90 TYR n 1 91 ASN n 1 92 SER n 1 93 ARG n 1 94 VAL n 1 95 GLU n 1 96 CYS n 1 97 ILE n 1 98 GLY n 1 99 TRP n 1 100 SER n 1 101 SER n 1 102 THR n 1 103 SER n 1 104 CYS n 1 105 HIS n 1 106 ASP n 1 107 GLY n 1 108 ARG n 1 109 ALA n 1 110 ARG n 1 111 MET n 1 112 SER n 1 113 ILE n 1 114 CYS n 1 115 ILE n 1 116 SER n 1 117 GLY n 1 118 PRO n 1 119 ASN n 1 120 ASN n 1 121 ASN n 1 122 ALA n 1 123 SER n 1 124 ALA n 1 125 VAL n 1 126 ILE n 1 127 TRP n 1 128 TYR n 1 129 ASN n 1 130 ARG n 1 131 ARG n 1 132 PRO n 1 133 VAL n 1 134 THR n 1 135 GLU n 1 136 ILE n 1 137 ASN n 1 138 THR n 1 139 TRP n 1 140 ALA n 1 141 ARG n 1 142 ASN n 1 143 ILE n 1 144 LEU n 1 145 ARG n 1 146 THR n 1 147 GLN n 1 148 GLU n 1 149 SER n 1 150 GLU n 1 151 CYS n 1 152 VAL n 1 153 CYS n 1 154 GLN n 1 155 ASN n 1 156 GLY n 1 157 VAL n 1 158 CYS n 1 159 PRO n 1 160 VAL n 1 161 VAL n 1 162 PHE n 1 163 THR n 1 164 ASP n 1 165 GLY n 1 166 SER n 1 167 ALA n 1 168 THR n 1 169 GLY n 1 170 PRO n 1 171 ALA n 1 172 GLU n 1 173 THR n 1 174 ARG n 1 175 ILE n 1 176 TYR n 1 177 TYR n 1 178 PHE n 1 179 LYS n 1 180 GLU n 1 181 GLY n 1 182 LYS n 1 183 ILE n 1 184 LEU n 1 185 LYS n 1 186 TRP n 1 187 GLU n 1 188 PRO n 1 189 LEU n 1 190 THR n 1 191 GLY n 1 192 THR n 1 193 ALA n 1 194 LYS n 1 195 HIS n 1 196 ILE n 1 197 GLU n 1 198 GLU n 1 199 CYS n 1 200 SER n 1 201 CYS n 1 202 TYR n 1 203 GLY n 1 204 GLU n 1 205 GLN n 1 206 ALA n 1 207 GLY n 1 208 VAL n 1 209 THR n 1 210 CYS n 1 211 THR n 1 212 CYS n 1 213 ARG n 1 214 ASP n 1 215 ASN n 1 216 TRP n 1 217 GLN n 1 218 GLY n 1 219 SER n 1 220 ASN n 1 221 ARG n 1 222 PRO n 1 223 VAL n 1 224 ILE n 1 225 GLN n 1 226 ILE n 1 227 ASP n 1 228 PRO n 1 229 VAL n 1 230 ALA n 1 231 MET n 1 232 THR n 1 233 HIS n 1 234 THR n 1 235 SER n 1 236 GLN n 1 237 TYR n 1 238 ILE n 1 239 CYS n 1 240 SER n 1 241 PRO n 1 242 VAL n 1 243 LEU n 1 244 THR n 1 245 ASP n 1 246 ASN n 1 247 PRO n 1 248 ARG n 1 249 PRO n 1 250 ASN n 1 251 ASP n 1 252 PRO n 1 253 THR n 1 254 VAL n 1 255 GLY n 1 256 LYS n 1 257 CYS n 1 258 ASN n 1 259 ASP n 1 260 PRO n 1 261 TYR n 1 262 PRO n 1 263 GLY n 1 264 ASN n 1 265 ASN n 1 266 ASN n 1 267 ASN n 1 268 GLY n 1 269 VAL n 1 270 LYS n 1 271 GLY n 1 272 PHE n 1 273 SER n 1 274 TYR n 1 275 LEU n 1 276 ASP n 1 277 GLY n 1 278 GLY n 1 279 ASN n 1 280 THR n 1 281 TRP n 1 282 LEU n 1 283 GLY n 1 284 ARG n 1 285 THR n 1 286 ILE n 1 287 SER n 1 288 ILE n 1 289 ALA n 1 290 SER n 1 291 ARG n 1 292 SER n 1 293 GLY n 1 294 TYR n 1 295 GLU n 1 296 MET n 1 297 LEU n 1 298 LYS n 1 299 VAL n 1 300 PRO n 1 301 ASN n 1 302 ALA n 1 303 LEU n 1 304 THR n 1 305 ASP n 1 306 ASP n 1 307 ARG n 1 308 SER n 1 309 LYS n 1 310 PRO n 1 311 THR n 1 312 GLN n 1 313 GLY n 1 314 GLN n 1 315 THR n 1 316 ILE n 1 317 VAL n 1 318 LEU n 1 319 ASN n 1 320 THR n 1 321 ASP n 1 322 TRP n 1 323 SER n 1 324 GLY n 1 325 TYR n 1 326 SER n 1 327 GLY n 1 328 SER n 1 329 PHE n 1 330 MET n 1 331 ASP n 1 332 TYR n 1 333 TRP n 1 334 ALA n 1 335 GLU n 1 336 GLY n 1 337 GLU n 1 338 CYS n 1 339 TYR n 1 340 ARG n 1 341 ALA n 1 342 CYS n 1 343 PHE n 1 344 TYR n 1 345 VAL n 1 346 GLU n 1 347 LEU n 1 348 ILE n 1 349 ARG n 1 350 GLY n 1 351 ARG n 1 352 PRO n 1 353 LYS n 1 354 GLU n 1 355 ASP n 1 356 LYS n 1 357 VAL n 1 358 TRP n 1 359 TRP n 1 360 THR n 1 361 SER n 1 362 ASN n 1 363 SER n 1 364 ILE n 1 365 VAL n 1 366 SER n 1 367 MET n 1 368 CYS n 1 369 SER n 1 370 SER n 1 371 THR n 1 372 GLU n 1 373 PHE n 1 374 LEU n 1 375 GLY n 1 376 GLN n 1 377 TRP n 1 378 ASN n 1 379 TRP n 1 380 PRO n 1 381 ASP n 1 382 GLY n 1 383 ALA n 1 384 LYS n 1 385 ILE n 1 386 GLU n 1 387 TYR n 1 388 PHE n 1 389 LEU n 2 1 ASP n 2 2 ILE n 2 3 VAL n 2 4 MET n 2 5 THR n 2 6 GLN n 2 7 SER n 2 8 PRO n 2 9 LYS n 2 10 PHE n 2 11 MET n 2 12 SER n 2 13 THR n 2 14 SER n 2 15 VAL n 2 16 GLY n 2 17 ASP n 2 18 ARG n 2 19 VAL n 2 20 THR n 2 21 ILE n 2 22 THR n 2 23 CYS n 2 24 LYS n 2 25 ALA n 2 26 SER n 2 27 GLN n 2 28 ASP n 2 29 VAL n 2 30 SER n 2 31 THR n 2 32 ALA n 2 33 VAL n 2 34 VAL n 2 35 TRP n 2 36 TYR n 2 37 GLN n 2 38 GLN n 2 39 LYS n 2 40 PRO n 2 41 GLY n 2 42 GLN n 2 43 SER n 2 44 PRO n 2 45 LYS n 2 46 LEU n 2 47 LEU n 2 48 ILE n 2 49 TYR n 2 50 TRP n 2 51 ALA n 2 52 SER n 2 53 THR n 2 54 ARG n 2 55 HIS n 2 56 ILE n 2 57 GLY n 2 58 VAL n 2 59 PRO n 2 60 ASP n 2 61 ARG n 2 62 PHE n 2 63 ALA n 2 64 GLY n 2 65 SER n 2 66 GLY n 2 67 SER n 2 68 GLY n 2 69 THR n 2 70 ASP n 2 71 TYR n 2 72 THR n 2 73 LEU n 2 74 THR n 2 75 ILE n 2 76 SER n 2 77 SER n 2 78 VAL n 2 79 GLN n 2 80 ALA n 2 81 GLU n 2 82 ASP n 2 83 LEU n 2 84 ALA n 2 85 LEU n 2 86 TYR n 2 87 TYR n 2 88 CYS n 2 89 GLN n 2 90 GLN n 2 91 HIS n 2 92 TYR n 2 93 SER n 2 94 PRO n 2 95 PRO n 2 96 TRP n 2 97 THR n 2 98 PHE n 2 99 GLY n 2 100 GLY n 2 101 GLY n 2 102 THR n 2 103 LYS n 2 104 LEU n 2 105 GLU n 2 106 ILE n 2 107 LYS n 2 108 ARG n 2 109 ALA n 2 110 ASP n 2 111 ALA n 2 112 ALA n 2 113 PRO n 2 114 THR n 2 115 VAL n 2 116 SER n 2 117 ILE n 2 118 PHE n 2 119 PRO n 2 120 PRO n 2 121 SER n 2 122 SER n 2 123 GLU n 2 124 GLN n 2 125 LEU n 2 126 THR n 2 127 SER n 2 128 GLY n 2 129 GLY n 2 130 ALA n 2 131 SER n 2 132 VAL n 2 133 VAL n 2 134 CYS n 2 135 PHE n 2 136 LEU n 2 137 ASN n 2 138 ASN n 2 139 PHE n 2 140 TYR n 2 141 PRO n 2 142 LYS n 2 143 ASP n 2 144 ILE n 2 145 ASN n 2 146 VAL n 2 147 LYS n 2 148 TRP n 2 149 LYS n 2 150 ILE n 2 151 ASP n 2 152 GLY n 2 153 SER n 2 154 GLU n 2 155 ARG n 2 156 GLN n 2 157 ASN n 2 158 GLY n 2 159 VAL n 2 160 LEU n 2 161 ASN n 2 162 SER n 2 163 TRP n 2 164 THR n 2 165 ASP n 2 166 GLN n 2 167 ASP n 2 168 SER n 2 169 LYS n 2 170 ASP n 2 171 SER n 2 172 THR n 2 173 TYR n 2 174 SER n 2 175 MET n 2 176 SER n 2 177 SER n 2 178 THR n 2 179 LEU n 2 180 THR n 2 181 LEU n 2 182 THR n 2 183 LYS n 2 184 ASP n 2 185 GLU n 2 186 TYR n 2 187 GLU n 2 188 ARG n 2 189 HIS n 2 190 ASN n 2 191 SER n 2 192 TYR n 2 193 THR n 2 194 CYS n 2 195 GLU n 2 196 ALA n 2 197 THR n 2 198 HIS n 2 199 LYS n 2 200 THR n 2 201 SER n 2 202 THR n 2 203 SER n 2 204 PRO n 2 205 ILE n 2 206 VAL n 2 207 LYS n 2 208 SER n 2 209 PHE n 2 210 ASN n 2 211 ARG n 2 212 ASN n 2 213 GLU n 2 214 CYS n 3 1 GLN n 3 2 ILE n 3 3 GLN n 3 4 LEU n 3 5 VAL n 3 6 GLN n 3 7 SER n 3 8 GLY n 3 9 PRO n 3 10 GLU n 3 11 LEU n 3 12 LYS n 3 13 LYS n 3 14 PRO n 3 15 GLY n 3 16 GLU n 3 17 THR n 3 18 VAL n 3 19 LYS n 3 20 ILE n 3 21 SER n 3 22 CYS n 3 23 LYS n 3 24 ALA n 3 25 SER n 3 26 GLY n 3 27 TYR n 3 28 THR n 3 29 PHE n 3 30 THR n 3 31 ASN n 3 32 TYR n 3 33 GLY n 3 34 MET n 3 35 ASN n 3 36 TRP n 3 37 VAL n 3 38 LYS n 3 39 GLN n 3 40 ALA n 3 41 PRO n 3 42 GLY n 3 43 LYS n 3 44 GLY n 3 45 LEU n 3 46 GLU n 3 47 TRP n 3 48 MET n 3 49 GLY n 3 50 TRP n 3 51 ILE n 3 52 ASN n 3 53 THR n 3 54 ASN n 3 55 THR n 3 56 GLY n 3 57 GLU n 3 58 PRO n 3 59 THR n 3 60 TYR n 3 61 GLY n 3 62 GLU n 3 63 GLU n 3 64 PHE n 3 65 LYS n 3 66 GLY n 3 67 ARG n 3 68 PHE n 3 69 ALA n 3 70 PHE n 3 71 SER n 3 72 LEU n 3 73 GLU n 3 74 THR n 3 75 SER n 3 76 ALA n 3 77 SER n 3 78 THR n 3 79 ALA n 3 80 ASN n 3 81 LEU n 3 82 GLN n 3 83 ILE n 3 84 ASN n 3 85 ASN n 3 86 LEU n 3 87 LYS n 3 88 ASN n 3 89 GLU n 3 90 ASP n 3 91 LYS n 3 92 ALA n 3 93 THR n 3 94 PHE n 3 95 PHE n 3 96 CYS n 3 97 ALA n 3 98 ARG n 3 99 GLY n 3 100 GLU n 3 101 ASP n 3 102 ASN n 3 103 PHE n 3 104 GLY n 3 105 SER n 3 106 LEU n 3 107 SER n 3 108 ASP n 3 109 TYR n 3 110 TRP n 3 111 GLY n 3 112 GLN n 3 113 GLY n 3 114 THR n 3 115 THR n 3 116 LEU n 3 117 THR n 3 118 VAL n 3 119 SER n 3 120 SER n 3 121 ALA n 3 122 LYS n 3 123 THR n 3 124 THR n 3 125 ALA n 3 126 PRO n 3 127 SER n 3 128 VAL n 3 129 TYR n 3 130 PRO n 3 131 LEU n 3 132 ALA n 3 133 PRO n 3 134 VAL n 3 135 CYS n 3 136 GLY n 3 137 ASP n 3 138 THR n 3 139 THR n 3 140 GLY n 3 141 SER n 3 142 SER n 3 143 VAL n 3 144 THR n 3 145 LEU n 3 146 GLY n 3 147 CYS n 3 148 LEU n 3 149 VAL n 3 150 LYS n 3 151 GLY n 3 152 TYR n 3 153 PHE n 3 154 PRO n 3 155 GLU n 3 156 PRO n 3 157 VAL n 3 158 THR n 3 159 LEU n 3 160 THR n 3 161 TRP n 3 162 ASN n 3 163 SER n 3 164 GLY n 3 165 SER n 3 166 LEU n 3 167 SER n 3 168 SER n 3 169 GLY n 3 170 VAL n 3 171 HIS n 3 172 THR n 3 173 PHE n 3 174 PRO n 3 175 ALA n 3 176 VAL n 3 177 LEU n 3 178 GLN n 3 179 SER n 3 180 ASP n 3 181 LEU n 3 182 TYR n 3 183 THR n 3 184 LEU n 3 185 SER n 3 186 SER n 3 187 SER n 3 188 VAL n 3 189 THR n 3 190 VAL n 3 191 THR n 3 192 SER n 3 193 SER n 3 194 THR n 3 195 TRP n 3 196 PRO n 3 197 SER n 3 198 GLN n 3 199 SER n 3 200 ILE n 3 201 THR n 3 202 CYS n 3 203 ASN n 3 204 VAL n 3 205 ALA n 3 206 HIS n 3 207 PRO n 3 208 ALA n 3 209 SER n 3 210 SER n 3 211 THR n 3 212 LYS n 3 213 VAL n 3 214 ASP n 3 215 LYS n 3 216 LYS n 3 217 ILE n 3 218 GLU n 3 219 PRO n 3 220 ARG n 3 221 GLY n # loop_ _entity_src_nat.entity_id _entity_src_nat.pdbx_src_id _entity_src_nat.pdbx_alt_source_flag _entity_src_nat.pdbx_beg_seq_num _entity_src_nat.pdbx_end_seq_num _entity_src_nat.common_name _entity_src_nat.pdbx_organism_scientific _entity_src_nat.pdbx_ncbi_taxonomy_id _entity_src_nat.genus _entity_src_nat.species _entity_src_nat.strain _entity_src_nat.tissue _entity_src_nat.tissue_fraction _entity_src_nat.pdbx_secretion _entity_src_nat.pdbx_fragment _entity_src_nat.pdbx_variant _entity_src_nat.pdbx_cell_line _entity_src_nat.pdbx_atcc _entity_src_nat.pdbx_cellular_location _entity_src_nat.pdbx_organ _entity_src_nat.pdbx_organelle _entity_src_nat.pdbx_cell _entity_src_nat.pdbx_plasmid_name _entity_src_nat.pdbx_plasmid_details _entity_src_nat.details 1 1 sample ? ? ? 'Influenza A virus' 11484 'Influenzavirus A' 'Influenza A virus' '(A/whale/Maine/1/84(H13N9))' ? ? ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample ? ? 'house mouse' 'Mus musculus' 10090 Mus ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 3 1 sample ? ? 'house mouse' 'Mus musculus' 10090 Mus ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.entity_id _struct_ref.pdbx_db_accession _struct_ref.pdbx_align_begin _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_db_isoform 1 UNP NRAM_IAWHM 1 P05803 1 ;MNPNQKILCTSATALVIGTIAVLIGIVNLGLNIGLHLKPSCNCSRSQPEATNASQTIINNYYNETNITQISNTNIQVEER ASREFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRDLI SWPLSSPPTVYNSRVECIGWSSTSCHDGRARMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCQNGVCP VVFTDGSATGPAETRIYYFKEGKILKWEPLTGTAKHIEECSCYGEQAGVTCTCRDNWQGSNRPVIQIDPVAMTHTSQYIC SPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGGNTWLGRTISIASRSGYEMLKVPNALTDDRSKPTQGQTIVLN TDWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL ; ? 2 EMBL CAA72328 2 Y11589 1 ;DIVMTQSPKFMSTSVGDRVSVTCKASQIVGTNVAWYQQKPGQSPKALIYSASYRYSGVPDRFTGSGSGTDFTLTISNVQS EDLAEYFCQQYNRYPWTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC ; ? 3 UNP GCAM_MOUSE 3 P01865 1 ;AKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSI TCNVAHPASSTKVDKKIEPRGPTIKPCPPCKCPAPNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISW FVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPPEEE MTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEKKNWVERNSYSCSVVHEGLHNHHT TKSFSRTPGLDLDDVCAEAQDGELDGLWTTITIFISLFLLSVCYSASVTLFKVKWIFSSVVELKQTISPDYRNMIGQGA ; ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 1NCD N 2 ? 389 ? P05803 83 ? 470 ? 82 468 2 2 1NCD L 1 ? 214 ? Y11589 1 ? 214 ? 1 214 3 3 1NCD H 121 ? 221 ? P01865 1 ? 101 ? 114 227 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 2 1NCD THR L 20 ? EMBL Y11589 SER 20 CONFLICT 20 1 2 1NCD ILE L 21 ? EMBL Y11589 VAL 21 CONFLICT 21 2 2 1NCD ASP L 28 ? EMBL Y11589 ILE 28 CONFLICT 28 3 2 1NCD SER L 30 ? EMBL Y11589 GLY 30 CONFLICT 30 4 2 1NCD ALA L 32 ? EMBL Y11589 ASN 32 CONFLICT 32 5 2 1NCD VAL L 34 ? EMBL Y11589 ALA 34 CONFLICT 34 6 2 1NCD LEU L 46 ? EMBL Y11589 ALA 46 CONFLICT 46 7 2 1NCD TRP L 50 ? EMBL Y11589 SER 50 CONFLICT 50 8 2 1NCD THR L 53 ? EMBL Y11589 TYR 53 CONFLICT 53 9 2 1NCD HIS L 55 ? EMBL Y11589 TYR 55 CONFLICT 55 10 2 1NCD ILE L 56 ? EMBL Y11589 SER 56 CONFLICT 56 11 2 1NCD ALA L 63 ? EMBL Y11589 THR 63 CONFLICT 63 12 2 1NCD TYR L 71 ? EMBL Y11589 PHE 71 CONFLICT 71 13 2 1NCD SER L 77 ? EMBL Y11589 ASN 77 CONFLICT 77 14 2 1NCD ALA L 80 ? EMBL Y11589 SER 80 CONFLICT 80 15 2 1NCD LEU L 85 ? EMBL Y11589 GLU 85 CONFLICT 85 16 2 1NCD TYR L 87 ? EMBL Y11589 PHE 87 CONFLICT 87 17 2 1NCD HIS L 91 ? EMBL Y11589 TYR 91 CONFLICT 91 18 2 1NCD TYR L 92 ? EMBL Y11589 ASN 92 CONFLICT 92 19 2 1NCD SER L 93 ? EMBL Y11589 ARG 93 CONFLICT 93 20 2 1NCD PRO L 94 ? EMBL Y11589 TYR 94 CONFLICT 94 21 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 BMA D-saccharide . BETA-D-MANNOSE ? 'C6 H12 O6' 180.156 CA non-polymer . 'CALCIUM ION' ? 'Ca 2' 40.078 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 1NCD _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number ? # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 4.74 _exptl_crystal.density_percent_sol 74.05 _exptl_crystal.description ? # _diffrn.id 1 _diffrn.ambient_temp ? _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l ? _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength . _diffrn_radiation_wavelength.wt 1.0 # _refine.entry_id 1NCD _refine.ls_number_reflns_obs 18737 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low ? _refine.ls_d_res_high 2.9 _refine.ls_percent_reflns_obs ? _refine.ls_R_factor_obs 0.157 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.157 _refine.ls_R_factor_R_free ? _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free ? _refine.ls_number_reflns_R_free ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.B_iso_mean ? _refine.aniso_B[1][1] ? _refine.aniso_B[2][2] ? _refine.aniso_B[3][3] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][3] ? _refine.solvent_model_details ? _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_ls_cross_valid_method ? _refine.details ;THE COORDINATES OF THE CALCIUM ATOM ARE NOT WELL DETERMINED. THE REFERENCE STRUCTURE FOR THE CALCIUM ATOM IS THE N9 MUTANT S370L (PDB ENTRY 2NN9) ; _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ? _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_overall_phase_error ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6401 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 115 _refine_hist.number_atoms_solvent 69 _refine_hist.number_atoms_total 6585 _refine_hist.d_res_high 2.9 _refine_hist.d_res_low . # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function x_bond_d 0.016 ? ? ? 'X-RAY DIFFRACTION' ? x_bond_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_bond_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_deg 3.6 ? ? ? 'X-RAY DIFFRACTION' ? x_angle_deg_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_deg_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_dihedral_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? x_dihedral_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_dihedral_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_improper_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? x_improper_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_improper_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_mcbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? x_mcangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? x_scbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? x_scangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? # _struct.entry_id 1NCD _struct.title 'REFINED CRYSTAL STRUCTURE OF THE INFLUENZA VIRUS N9 NEURAMINIDASE-NC41 FAB COMPLEX' _struct.pdbx_descriptor 'N9 NEURAMINIDASE-NC41 (E.C.3.2.1.18) COMPLEX WITH FAB' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 1NCD _struct_keywords.pdbx_keywords 'HYDROLASE(O-GLYCOSYL)' _struct_keywords.text 'HYDROLASE(O-GLYCOSYL)' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 4 ? F N N 5 ? G N N 6 ? H N N 6 ? I N N 6 ? J N N 4 ? K N N 4 ? L N N 4 ? M N N 7 ? N N N 8 ? O N N 8 ? P N N 8 ? # _struct_biol.id 1 _struct_biol.details ;THE COORDINATES OF THE CARBOHYDRATE IN THE EPITOPE CAN BE GENERATED FORM THE COORDINATES OF RESIDUES C 200A-C 200F BY APPLYING THE FOLLOWING TRANSFORMATION: 0.0 1.0 0.0 83.5 -1.0 0.0 0.0 83.5 0.0 0.0 1.0 0.0 ; _struct_biol.pdbx_parent_biol_id ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 H1 ASN A 24 ? ASP A 31 ? ASN N 104 ASP N 111 1 ? 8 HELX_P HELX_P2 H2 GLY A 62 ? ASN A 66 ? GLY N 142 ASN N 146 1 ? 5 HELX_P HELX_P3 H3 ASN A 301 ? ASP A 305 ? ASN N 381 ASP N 385 1 ? 5 HELX_P HELX_P4 H4 LYS A 384 ? LEU A 389 ? LYS N 463 LEU N 468 1 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 12 SG ? ? ? 1_555 A CYS 338 SG ? ? N CYS 92 N CYS 417 1_555 ? ? ? ? ? ? ? 2.004 ? disulf2 disulf ? ? A CYS 44 SG ? ? ? 1_555 A CYS 49 SG ? ? N CYS 124 N CYS 129 1_555 ? ? ? ? ? ? ? 2.005 ? disulf3 disulf ? ? A CYS 96 SG ? ? ? 1_555 A CYS 114 SG ? ? N CYS 175 N CYS 193 1_555 ? ? ? ? ? ? ? 1.985 ? disulf4 disulf ? ? A CYS 104 SG ? ? ? 1_555 A CYS 151 SG ? ? N CYS 183 N CYS 230 1_555 ? ? ? ? ? ? ? 2.003 ? disulf5 disulf ? ? A CYS 153 SG ? ? ? 1_555 A CYS 158 SG ? ? N CYS 232 N CYS 237 1_555 ? ? ? ? ? ? ? 1.974 ? disulf6 disulf ? ? A CYS 199 SG ? ? ? 1_555 A CYS 212 SG ? ? N CYS 278 N CYS 291 1_555 ? ? ? ? ? ? ? 2.025 ? disulf7 disulf ? ? A CYS 201 SG ? ? ? 1_555 A CYS 210 SG ? ? N CYS 280 N CYS 289 1_555 ? ? ? ? ? ? ? 1.990 ? disulf8 disulf ? ? A CYS 239 SG ? ? ? 1_555 A CYS 257 SG ? ? N CYS 318 N CYS 337 1_555 ? ? ? ? ? ? ? 1.973 ? disulf9 disulf ? ? A CYS 342 SG ? ? ? 1_555 A CYS 368 SG ? ? N CYS 421 N CYS 447 1_555 ? ? ? ? ? ? ? 2.031 ? disulf10 disulf ? ? B CYS 23 SG ? ? ? 1_555 B CYS 88 SG ? ? L CYS 23 L CYS 88 1_555 ? ? ? ? ? ? ? 2.014 ? disulf11 disulf ? ? B CYS 134 SG ? ? ? 1_555 B CYS 194 SG ? ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.015 ? disulf12 disulf ? ? B CYS 214 SG ? ? ? 1_555 C CYS 135 SG ? ? L CYS 214 H CYS 128 1_555 ? ? ? ? ? ? ? 2.016 ? disulf13 disulf ? ? C CYS 22 SG ? ? ? 1_555 C CYS 96 SG ? ? H CYS 22 H CYS 92 1_555 ? ? ? ? ? ? ? 2.011 ? disulf14 disulf ? ? C CYS 147 SG ? ? ? 1_555 C CYS 202 SG ? ? H CYS 142 H CYS 208 1_555 ? ? ? ? ? ? ? 2.008 ? covale1 covale ? ? A ASN 6 ND2 ? ? ? 1_555 J NAG . C1 ? A N ASN 86 N NAG 475 1_555 ? ? ? ? ? ? ? 1.462 ? covale2 covale ? ? A ASN 66 ND2 ? ? ? 1_555 K NAG . C1 ? A N ASN 146 N NAG 476 1_555 ? ? ? ? ? ? ? 1.445 ? covale3 covale ? ? A ASN 121 ND2 ? ? ? 1_555 D NAG . C1 ? A N ASN 200 N NAG 469 1_555 ? ? ? ? ? ? ? 1.472 ? covale4 covale ? ? D NAG . O4 ? A ? 1_555 E NAG . C1 ? B N NAG 469 N NAG 470 1_555 ? ? ? ? ? ? ? 1.443 ? covale5 covale ? ? E NAG . O4 ? B ? 1_555 F BMA . C1 ? C N NAG 470 N BMA 471 1_555 ? ? ? ? ? ? ? 1.429 ? covale6 covale ? ? F BMA . O3 ? C ? 1_555 G MAN . C1 ? D N BMA 471 N MAN 472 1_555 ? ? ? ? ? ? ? 1.439 ? covale7 covale ? ? G MAN . O2 ? D ? 1_555 H MAN . C1 ? E N MAN 472 N MAN 473 1_555 ? ? ? ? ? ? ? 1.448 ? covale8 covale ? ? H MAN . O2 ? E ? 1_555 I MAN . C1 ? F N MAN 473 N MAN 474 1_555 ? ? ? ? ? ? ? 1.413 ? covale9 covale ? ? K NAG . O4 ? A ? 1_555 L NAG . C1 ? B N NAG 476 N NAG 477 1_555 ? ? ? ? ? ? ? 1.443 ? metalc1 metalc ? ? M CA . CA ? ? ? 1_555 A ASN 215 O ? ? N CA 0 N ASN 294 1_555 ? ? ? ? ? ? ? 3.207 ? metalc2 metalc ? ? M CA . CA ? ? ? 1_555 A ASP 245 OD2 ? ? N CA 0 N ASP 324 1_555 ? ? ? ? ? ? ? 3.001 ? metalc3 metalc ? ? M CA . CA ? ? ? 1_555 A GLY 218 O ? ? N CA 0 N GLY 297 1_555 ? ? ? ? ? ? ? 1.625 ? metalc4 metalc ? ? M CA . CA ? ? ? 1_555 A ASP 214 O ? ? N CA 0 N ASP 293 1_555 ? ? ? ? ? ? ? 3.003 ? metalc5 metalc ? ? M CA . CA ? ? ? 1_555 A ASN 267 O ? ? N CA 0 N ASN 347 1_555 ? ? ? ? ? ? ? 2.103 ? metalc6 metalc ? ? M CA . CA ? ? ? 1_555 A ASN 264 O ? ? N CA 0 N ASN 344 1_555 ? ? ? ? ? ? ? 2.870 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 ASN 246 A . ? ASN 325 N PRO 247 A ? PRO 326 N 1 4.73 2 ARG 351 A . ? ARG 430 N PRO 352 A ? PRO 431 N 1 11.20 3 SER 7 B . ? SER 7 L PRO 8 B ? PRO 8 L 1 -1.99 4 PRO 94 B . ? PRO 94 L PRO 95 B ? PRO 95 L 1 -13.79 5 TYR 140 B . ? TYR 140 L PRO 141 B ? PRO 141 L 1 -1.23 6 PHE 153 C . ? PHE 148 H PRO 154 C ? PRO 149 H 1 0.01 7 GLU 155 C . ? GLU 150 H PRO 156 C ? PRO 151 H 1 4.77 8 TRP 195 C . ? TRP 199 H PRO 196 C ? PRO 200 H 1 5.77 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 4 ? B ? 4 ? C ? 4 ? D ? 4 ? E ? 4 ? F ? 4 ? G ? 4 ? H ? 6 ? I ? 4 ? J ? 4 ? K ? 4 ? L ? 5 ? M ? 6 ? N ? 4 ? O ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel C 3 4 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel G 1 2 ? anti-parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel H 1 2 ? parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel H 5 6 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel L 1 2 ? anti-parallel L 2 3 ? anti-parallel L 3 4 ? anti-parallel M 1 2 ? anti-parallel M 2 3 ? anti-parallel M 3 4 ? anti-parallel M 4 5 ? anti-parallel M 5 6 ? parallel N 1 2 ? anti-parallel N 2 3 ? anti-parallel N 3 4 ? anti-parallel O 1 2 ? anti-parallel O 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 SER A 16 ? LYS A 22 ? SER N 96 LYS N 102 A 2 THR A 360 ? SER A 370 ? THR N 439 SER N 449 A 3 CYS A 342 ? GLY A 350 ? CYS N 421 GLY N 429 A 4 SER A 326 ? PHE A 329 ? SER N 407 PHE N 410 B 1 LEU A 35 ? ASP A 45 ? LEU N 115 ASP N 125 B 2 GLU A 48 ? THR A 59 ? GLU N 128 THR N 139 B 3 ASP A 77 ? PRO A 82 ? ASP N 157 PRO N 162 B 4 ARG A 93 ? ILE A 97 ? ARG N 172 ILE N 176 C 1 SER A 100 ? HIS A 105 ? SER N 179 HIS N 184 C 2 ARG A 110 ? SER A 116 ? ARG N 189 SER N 195 C 3 SER A 123 ? TYR A 128 ? SER N 202 TYR N 207 C 4 PRO A 132 ? ASN A 137 ? PRO N 211 ASN N 216 D 1 ARG A 145 ? THR A 146 ? ARG N 224 THR N 225 D 2 VAL A 157 ? GLY A 165 ? VAL N 236 GLY N 244 D 3 ALA A 171 ? LYS A 179 ? ALA N 250 LYS N 258 D 4 LYS A 182 ? PRO A 188 ? LYS N 261 PRO N 267 E 1 GLU A 197 ? GLU A 204 ? GLU N 276 GLU N 283 E 2 GLY A 207 ? ARG A 213 ? GLY N 286 ARG N 292 E 3 PRO A 222 ? ASP A 227 ? PRO N 301 ASP N 306 E 4 THR A 232 ? TYR A 237 ? THR N 311 TYR N 316 F 1 SER A 273 ? TYR A 274 ? SER N 353 TYR N 354 F 2 TRP A 281 ? ARG A 284 ? TRP N 361 ARG N 364 F 3 SER A 292 ? LYS A 298 ? SER N 372 LYS N 378 F 4 GLN A 312 ? TRP A 322 ? GLN N 392 TRP N 403 G 1 MET B 4 ? GLN B 6 ? MET L 4 GLN L 6 G 2 VAL B 19 ? ALA B 25 ? VAL L 19 ALA L 25 G 3 ASP B 70 ? ILE B 75 ? ASP L 70 ILE L 75 G 4 PHE B 62 ? SER B 67 ? PHE L 62 SER L 67 H 1 PHE B 10 ? SER B 14 ? PHE L 10 SER L 14 H 2 THR B 102 ? LYS B 107 ? THR L 102 LYS L 107 H 3 ALA B 84 ? GLN B 90 ? ALA L 84 GLN L 90 H 4 VAL B 33 ? GLN B 38 ? VAL L 33 GLN L 38 H 5 PRO B 44 ? TYR B 49 ? PRO L 44 TYR L 49 H 6 THR B 53 ? ARG B 54 ? THR L 53 ARG L 54 I 1 THR B 114 ? PHE B 118 ? THR L 114 PHE L 118 I 2 GLY B 129 ? PHE B 139 ? GLY L 129 PHE L 139 I 3 TYR B 173 ? THR B 182 ? TYR L 173 THR L 182 I 4 VAL B 159 ? TRP B 163 ? VAL L 159 TRP L 163 J 1 SER B 153 ? ARG B 155 ? SER L 153 ARG L 155 J 2 ILE B 144 ? ILE B 150 ? ILE L 144 ILE L 150 J 3 TYR B 192 ? HIS B 198 ? TYR L 192 HIS L 198 J 4 ILE B 205 ? PHE B 209 ? ILE L 205 PHE L 209 K 1 GLN C 3 ? GLN C 6 ? GLN H 3 GLN H 6 K 2 VAL C 18 ? SER C 25 ? VAL H 18 SER H 25 K 3 THR C 78 ? ILE C 83 ? THR H 77 ILE H 82 K 4 PHE C 68 ? GLU C 73 ? PHE H 67 GLU H 72 L 1 PRO C 58 ? TYR C 60 ? PRO H 57 TYR H 59 L 2 GLY C 44 ? ILE C 51 ? GLY H 44 ILE H 51 L 3 MET C 34 ? ALA C 40 ? MET H 34 ALA H 40 L 4 ALA C 92 ? GLY C 99 ? ALA H 88 GLY H 95 M 1 PRO C 58 ? TYR C 60 ? PRO H 57 TYR H 59 M 2 GLY C 44 ? ILE C 51 ? GLY H 44 ILE H 51 M 3 MET C 34 ? ALA C 40 ? MET H 34 ALA H 40 M 4 ALA C 92 ? GLY C 99 ? ALA H 88 GLY H 95 M 5 THR C 114 ? VAL C 118 ? THR H 107 VAL H 111 M 6 GLU C 10 ? LYS C 12 ? GLU H 10 LYS H 12 N 1 SER C 127 ? LEU C 131 ? SER H 120 LEU H 124 N 2 SER C 142 ? TYR C 152 ? SER H 137 TYR H 147 N 3 LEU C 181 ? THR C 191 ? LEU H 184 THR H 194 N 4 HIS C 171 ? GLN C 178 ? HIS H 172 GLN H 179 O 1 THR C 158 ? TRP C 161 ? THR H 153 TRP H 157 O 2 THR C 201 ? HIS C 206 ? THR H 206 HIS H 212 O 3 THR C 211 ? LYS C 216 ? THR H 217 LYS H 222 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N TYR A 20 ? N TYR N 100 O SER A 366 ? O SER N 445 A 2 3 O MET A 367 ? O MET N 446 N PHE A 343 ? N PHE N 422 A 3 4 N TYR A 344 ? N TYR N 423 O GLY A 327 ? O GLY N 408 B 1 2 N ASP A 45 ? N ASP N 125 O GLU A 48 ? O GLU N 128 B 2 3 N SER A 55 ? N SER N 135 O ASP A 77 ? O ASP N 157 B 3 4 O SER A 80 ? O SER N 160 N ARG A 93 ? N ARG N 172 C 1 2 O CYS A 104 ? O CYS N 183 N MET A 111 ? N MET N 190 C 2 3 O SER A 116 ? O SER N 195 N SER A 123 ? N SER N 202 C 3 4 O ILE A 126 ? O ILE N 205 N VAL A 133 ? N VAL N 212 D 1 2 O ARG A 145 ? O ARG N 224 N THR A 163 ? N THR N 242 D 2 3 O ASP A 164 ? O ASP N 243 N GLU A 172 ? N GLU N 251 D 3 4 N LYS A 179 ? N LYS N 258 O LYS A 182 ? O LYS N 261 E 1 2 N GLU A 204 ? N GLU N 283 O GLY A 207 ? O GLY N 286 E 2 3 N CYS A 212 ? N CYS N 291 O PRO A 222 ? O PRO N 301 E 3 4 N ASP A 227 ? N ASP N 306 O THR A 232 ? O THR N 311 F 1 2 N TYR A 274 ? N TYR N 354 O TRP A 281 ? O TRP N 361 F 2 3 O ARG A 284 ? O ARG N 364 N GLU A 295 ? N GLU N 375 F 3 4 N LYS A 298 ? N LYS N 378 O GLN A 312 ? O GLN N 392 G 1 2 N THR B 5 ? N THR L 5 O LYS B 24 ? O LYS L 24 G 2 3 O CYS B 23 ? O CYS L 23 N TYR B 71 ? N TYR L 71 G 3 4 N THR B 74 ? N THR L 74 O ALA B 63 ? O ALA L 63 H 1 2 N MET B 11 ? N MET L 11 O LYS B 103 ? O LYS L 103 H 2 3 N LEU B 104 ? N LEU L 104 O ALA B 84 ? O ALA L 84 H 3 4 O GLN B 89 ? O GLN L 89 N VAL B 34 ? N VAL L 34 H 4 5 N GLN B 37 ? N GLN L 37 O LYS B 45 ? O LYS L 45 H 5 6 O TYR B 49 ? O TYR L 49 N THR B 53 ? N THR L 53 I 1 2 O PHE B 118 ? O PHE L 118 N VAL B 133 ? N VAL L 133 I 2 3 O PHE B 139 ? O PHE L 139 N TYR B 173 ? N TYR L 173 I 3 4 N THR B 178 ? N THR L 178 O LEU B 160 ? O LEU L 160 J 1 2 N ARG B 155 ? N ARG L 155 O TRP B 148 ? O TRP L 148 J 2 3 N LYS B 149 ? N LYS L 149 O THR B 193 ? O THR L 193 J 3 4 N ALA B 196 ? N ALA L 196 O ILE B 205 ? O ILE L 205 K 1 2 O VAL C 5 ? O VAL H 5 N LYS C 23 ? N LYS H 23 K 2 3 N CYS C 22 ? N CYS H 22 O ALA C 79 ? O ALA H 78 K 3 4 N GLN C 82 ? N GLN H 81 O ALA C 69 ? O ALA H 68 L 1 2 N THR C 59 ? N THR H 58 O TRP C 50 ? O TRP H 50 L 2 3 N ILE C 51 ? N ILE H 51 O MET C 34 ? O MET H 34 L 3 4 O GLN C 39 ? O GLN H 39 N THR C 93 ? N THR H 89 M 1 2 N THR C 59 ? N THR H 58 O TRP C 50 ? O TRP H 50 M 2 3 N ILE C 51 ? N ILE H 51 O MET C 34 ? O MET H 34 M 3 4 O GLN C 39 ? O GLN H 39 N THR C 93 ? N THR H 89 M 4 5 N PHE C 94 ? N PHE H 90 O THR C 114 ? O THR H 107 M 5 6 O THR C 115 ? O THR H 108 N GLU C 10 ? N GLU H 10 N 1 2 O LEU C 131 ? O LEU H 124 N GLY C 146 ? N GLY H 141 N 2 3 O TYR C 152 ? O TYR H 147 N TYR C 182 ? N TYR H 185 N 3 4 N SER C 187 ? N SER H 190 O HIS C 171 ? O HIS H 172 O 1 2 O THR C 160 ? O THR H 156 N ASN C 203 ? N ASN H 209 O 2 3 O HIS C 206 ? O HIS H 212 N THR C 211 ? N THR H 217 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE NAG N 469A' AC2 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG N 470B' AC3 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE BMA N 471C' AC4 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE MAN N 472D' AC5 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE MAN N 473E' AC6 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE MAN N 474F' AC7 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG N 475A' AC8 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG N 476A' AC9 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG N 477B' BC1 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE CA N 0' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 8 ASN A 120 ? ASN N 199 . ? 1_555 ? 2 AC1 8 ASN A 121 ? ASN N 200 . ? 1_555 ? 3 AC1 8 LEU A 374 ? LEU N 453 . ? 3_545 ? 4 AC1 8 GLY A 375 ? GLY N 454 . ? 3_545 ? 5 AC1 8 GLN A 376 ? GLN N 455 . ? 3_545 ? 6 AC1 8 NAG E . B NAG N 470 . ? 1_555 ? 7 AC1 8 HOH N . ? HOH N 502 . ? 3_545 ? 8 AC1 8 HOH N . ? HOH N 539 . ? 3_545 ? 9 AC2 6 GLN A 312 ? GLN N 392 . ? 3_545 ? 10 AC2 6 GLY A 313 ? GLY N 394 . ? 3_545 ? 11 AC2 6 PHE A 373 ? PHE N 452 . ? 3_545 ? 12 AC2 6 NAG D . A NAG N 469 . ? 1_555 ? 13 AC2 6 BMA F . C BMA N 471 . ? 1_555 ? 14 AC2 6 HOH N . ? HOH N 502 . ? 3_545 ? 15 AC3 6 LEU A 297 ? LEU N 377 . ? 3_545 ? 16 AC3 6 THR A 311 ? THR N 391 . ? 3_545 ? 17 AC3 6 GLY A 313 ? GLY N 394 . ? 3_545 ? 18 AC3 6 NAG E . B NAG N 470 . ? 1_555 ? 19 AC3 6 MAN G . D MAN N 472 . ? 1_555 ? 20 AC3 6 HOH N . ? HOH N 536 . ? 3_545 ? 21 AC4 5 ARG A 284 ? ARG N 364 . ? 3_545 ? 22 AC4 5 GLU A 295 ? GLU N 375 . ? 3_545 ? 23 AC4 5 BMA F . C BMA N 471 . ? 1_555 ? 24 AC4 5 MAN H . E MAN N 473 . ? 1_555 ? 25 AC4 5 MAN I . F MAN N 474 . ? 1_555 ? 26 AC5 7 VAL A 242 ? VAL N 321 . ? 3_545 ? 27 AC5 7 ASP A 251 ? ASP N 330 . ? 3_545 ? 28 AC5 7 ARG A 284 ? ARG N 364 . ? 3_545 ? 29 AC5 7 LYS A 309 ? LYS N 389 . ? 3_545 ? 30 AC5 7 PRO A 310 ? PRO N 390 . ? 3_545 ? 31 AC5 7 MAN G . D MAN N 472 . ? 1_555 ? 32 AC5 7 MAN I . F MAN N 474 . ? 1_555 ? 33 AC6 8 ARG A 248 ? ARG N 327 . ? 3_545 ? 34 AC6 8 ASN A 250 ? ASN N 329 . ? 3_545 ? 35 AC6 8 ASP A 251 ? ASP N 330 . ? 3_545 ? 36 AC6 8 ARG A 284 ? ARG N 364 . ? 3_545 ? 37 AC6 8 ILE A 286 ? ILE N 366 . ? 3_545 ? 38 AC6 8 ILE A 288 ? ILE N 368 . ? 3_545 ? 39 AC6 8 MAN G . D MAN N 472 . ? 1_555 ? 40 AC6 8 MAN H . E MAN N 473 . ? 1_555 ? 41 AC7 4 GLU A 3 ? GLU N 83 . ? 1_555 ? 42 AC7 4 ASN A 6 ? ASN N 86 . ? 1_555 ? 43 AC7 4 GLN A 154 ? GLN N 233 . ? 1_555 ? 44 AC7 4 ASN A 155 ? ASN N 234 . ? 1_555 ? 45 AC8 3 ASN A 66 ? ASN N 146 . ? 1_555 ? 46 AC8 3 TRP A 358 ? TRP N 437 . ? 1_555 ? 47 AC8 3 NAG L . B NAG N 477 . ? 1_555 ? 48 AC9 2 TRP A 358 ? TRP N 437 . ? 1_555 ? 49 AC9 2 NAG K . A NAG N 476 . ? 1_555 ? 50 BC1 6 ASP A 214 ? ASP N 293 . ? 1_555 ? 51 BC1 6 ASN A 215 ? ASN N 294 . ? 1_555 ? 52 BC1 6 GLY A 218 ? GLY N 297 . ? 1_555 ? 53 BC1 6 ASP A 245 ? ASP N 324 . ? 1_555 ? 54 BC1 6 ASN A 264 ? ASN N 344 . ? 1_555 ? 55 BC1 6 ASN A 267 ? ASN N 347 . ? 1_555 ? # _database_PDB_matrix.entry_id 1NCD _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 1NCD _atom_sites.fract_transf_matrix[1][1] 0.005988 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.005988 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.008065 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_sites_footnote.id _atom_sites_footnote.text 1 'RESIDUES PRO N 326, PRO N 431, PRO L 8, PRO L 95, PRO L 141, PRO H 149, PRO H 151 AND PRO H 200 ARE CIS PROLINES.' 2 ;THE COORDINATES OF THE CALCIUM ATOM ARE NOT WELL DETERMINED. THE REFERENCE STRUCTURE FOR THE CALCIUM ATOM IS THE N9 MUTANT S370L (PDB ENTRY 2NN9). ; # loop_ _atom_type.symbol C CA N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ILE A 1 1 ? 70.951 8.075 153.644 1.00 48.53 ? 81 ILE N N 1 ATOM 2 C CA . ILE A 1 1 ? 71.211 8.351 155.038 1.00 46.56 ? 81 ILE N CA 1 ATOM 3 C C . ILE A 1 1 ? 70.846 6.984 155.638 1.00 45.34 ? 81 ILE N C 1 ATOM 4 O O . ILE A 1 1 ? 70.466 6.094 154.859 1.00 46.53 ? 81 ILE N O 1 ATOM 5 C CB . ILE A 1 1 ? 70.294 9.613 155.487 1.00 47.07 ? 81 ILE N CB 1 ATOM 6 C CG1 . ILE A 1 1 ? 69.882 9.611 156.988 1.00 48.42 ? 81 ILE N CG1 1 ATOM 7 C CG2 . ILE A 1 1 ? 68.997 9.611 154.691 1.00 46.05 ? 81 ILE N CG2 1 ATOM 8 C CD1 . ILE A 1 1 ? 70.863 9.888 158.160 1.00 49.48 ? 81 ILE N CD1 1 ATOM 9 N N . ARG A 1 2 ? 71.074 6.730 156.939 1.00 42.05 ? 82 ARG N N 1 ATOM 10 C CA . ARG A 1 2 ? 70.675 5.473 157.546 1.00 37.03 ? 82 ARG N CA 1 ATOM 11 C C . ARG A 1 2 ? 69.260 5.612 158.093 1.00 33.07 ? 82 ARG N C 1 ATOM 12 O O . ARG A 1 2 ? 68.721 4.717 158.742 1.00 32.82 ? 82 ARG N O 1 ATOM 13 C CB . ARG A 1 2 ? 71.650 5.118 158.659 1.00 38.02 ? 82 ARG N CB 1 ATOM 14 C CG . ARG A 1 2 ? 71.645 3.625 158.949 1.00 38.71 ? 82 ARG N CG 1 ATOM 15 C CD . ARG A 1 2 ? 72.646 3.262 160.033 1.00 39.33 ? 82 ARG N CD 1 ATOM 16 N NE . ARG A 1 2 ? 73.995 3.660 159.660 1.00 39.71 ? 82 ARG N NE 1 ATOM 17 C CZ . ARG A 1 2 ? 74.790 2.924 158.876 1.00 39.88 ? 82 ARG N CZ 1 ATOM 18 N NH1 . ARG A 1 2 ? 74.400 1.763 158.342 1.00 40.67 ? 82 ARG N NH1 1 ATOM 19 N NH2 . ARG A 1 2 ? 75.999 3.397 158.602 1.00 39.30 ? 82 ARG N NH2 1 ATOM 20 N N . GLU A 1 3 ? 68.582 6.704 157.745 1.00 29.27 ? 83 GLU N N 1 ATOM 21 C CA . GLU A 1 3 ? 67.308 7.021 158.322 1.00 24.80 ? 83 GLU N CA 1 ATOM 22 C C . GLU A 1 3 ? 66.387 7.613 157.276 1.00 21.45 ? 83 GLU N C 1 ATOM 23 O O . GLU A 1 3 ? 66.905 8.172 156.297 1.00 21.52 ? 83 GLU N O 1 ATOM 24 C CB . GLU A 1 3 ? 67.684 7.929 159.380 1.00 27.19 ? 83 GLU N CB 1 ATOM 25 C CG . GLU A 1 3 ? 66.579 7.980 160.357 1.00 28.94 ? 83 GLU N CG 1 ATOM 26 C CD . GLU A 1 3 ? 66.894 9.120 161.306 1.00 2.63 ? 83 GLU N CD 1 ATOM 27 O OE1 . GLU A 1 3 ? 67.056 10.261 160.789 1.00 2.35 ? 83 GLU N OE1 1 ATOM 28 O OE2 . GLU A 1 3 ? 66.982 8.857 162.546 1.00 2.47 ? 83 GLU N OE2 1 ATOM 29 N N . PHE A 1 4 ? 65.057 7.465 157.416 1.00 19.03 ? 84 PHE N N 1 ATOM 30 C CA . PHE A 1 4 ? 64.146 7.985 156.386 1.00 16.64 ? 84 PHE N CA 1 ATOM 31 C C . PHE A 1 4 ? 64.288 9.474 156.269 1.00 17.19 ? 84 PHE N C 1 ATOM 32 O O . PHE A 1 4 ? 64.908 10.091 157.139 1.00 17.80 ? 84 PHE N O 1 ATOM 33 C CB . PHE A 1 4 ? 62.677 7.733 156.660 1.00 14.58 ? 84 PHE N CB 1 ATOM 34 C CG . PHE A 1 4 ? 62.259 6.289 156.430 1.00 14.39 ? 84 PHE N CG 1 ATOM 35 C CD1 . PHE A 1 4 ? 62.342 5.704 155.170 1.00 13.83 ? 84 PHE N CD1 1 ATOM 36 C CD2 . PHE A 1 4 ? 61.780 5.522 157.476 1.00 14.05 ? 84 PHE N CD2 1 ATOM 37 C CE1 . PHE A 1 4 ? 61.982 4.382 154.954 1.00 11.51 ? 84 PHE N CE1 1 ATOM 38 C CE2 . PHE A 1 4 ? 61.426 4.196 157.247 1.00 12.07 ? 84 PHE N CE2 1 ATOM 39 C CZ . PHE A 1 4 ? 61.516 3.621 155.988 1.00 9.69 ? 84 PHE N CZ 1 ATOM 40 N N . ASN A 1 5 ? 63.764 10.096 155.231 1.00 16.25 ? 85 ASN N N 1 ATOM 41 C CA . ASN A 1 5 ? 63.932 11.538 155.100 1.00 15.51 ? 85 ASN N CA 1 ATOM 42 C C . ASN A 1 5 ? 62.669 12.355 155.338 1.00 16.81 ? 85 ASN N C 1 ATOM 43 O O . ASN A 1 5 ? 61.618 11.894 154.906 1.00 17.86 ? 85 ASN N O 1 ATOM 44 C CB . ASN A 1 5 ? 64.504 11.756 153.712 1.00 14.92 ? 85 ASN N CB 1 ATOM 45 C CG . ASN A 1 5 ? 64.795 13.198 153.320 1.00 14.49 ? 85 ASN N CG 1 ATOM 46 O OD1 . ASN A 1 5 ? 64.590 13.562 152.161 1.00 15.23 ? 85 ASN N OD1 1 ATOM 47 N ND2 . ASN A 1 5 ? 65.278 14.090 154.186 1.00 14.05 ? 85 ASN N ND2 1 ATOM 48 N N . ASN A 1 6 ? 62.654 13.508 156.018 1.00 16.87 ? 86 ASN N N 1 ATOM 49 C CA . ASN A 1 6 ? 61.441 14.314 156.214 1.00 14.83 ? 86 ASN N CA 1 ATOM 50 C C . ASN A 1 6 ? 61.661 15.594 155.442 1.00 10.53 ? 86 ASN N C 1 ATOM 51 O O . ASN A 1 6 ? 62.781 16.106 155.496 1.00 10.31 ? 86 ASN N O 1 ATOM 52 C CB . ASN A 1 6 ? 61.216 14.666 157.680 1.00 19.71 ? 86 ASN N CB 1 ATOM 53 C CG . ASN A 1 6 ? 60.789 13.450 158.466 1.00 25.65 ? 86 ASN N CG 1 ATOM 54 O OD1 . ASN A 1 6 ? 60.735 12.336 157.937 1.00 23.91 ? 86 ASN N OD1 1 ATOM 55 N ND2 . ASN A 1 6 ? 60.480 13.598 159.753 1.00 31.48 ? 86 ASN N ND2 1 ATOM 56 N N . LEU A 1 7 ? 60.717 16.172 154.707 1.00 8.18 ? 87 LEU N N 1 ATOM 57 C CA . LEU A 1 7 ? 61.006 17.355 153.904 1.00 6.81 ? 87 LEU N CA 1 ATOM 58 C C . LEU A 1 7 ? 60.840 18.509 154.844 1.00 7.36 ? 87 LEU N C 1 ATOM 59 O O . LEU A 1 7 ? 59.760 19.075 154.960 1.00 7.73 ? 87 LEU N O 1 ATOM 60 C CB . LEU A 1 7 ? 60.017 17.470 152.719 1.00 5.05 ? 87 LEU N CB 1 ATOM 61 C CG . LEU A 1 7 ? 59.737 16.198 151.925 1.00 3.22 ? 87 LEU N CG 1 ATOM 62 C CD1 . LEU A 1 7 ? 58.397 16.350 151.286 1.00 2.00 ? 87 LEU N CD1 1 ATOM 63 C CD2 . LEU A 1 7 ? 60.882 15.892 150.952 1.00 3.87 ? 87 LEU N CD2 1 ATOM 64 N N . THR A 1 8 ? 61.909 18.834 155.529 1.00 5.27 ? 88 THR N N 1 ATOM 65 C CA . THR A 1 8 ? 61.819 19.838 156.543 1.00 3.26 ? 88 THR N CA 1 ATOM 66 C C . THR A 1 8 ? 62.021 21.208 156.068 1.00 4.99 ? 88 THR N C 1 ATOM 67 O O . THR A 1 8 ? 61.566 22.105 156.765 1.00 8.87 ? 88 THR N O 1 ATOM 68 C CB . THR A 1 8 ? 62.828 19.621 157.642 1.00 2.60 ? 88 THR N CB 1 ATOM 69 O OG1 . THR A 1 8 ? 64.137 19.642 157.083 1.00 3.27 ? 88 THR N OG1 1 ATOM 70 C CG2 . THR A 1 8 ? 62.514 18.315 158.357 1.00 5.14 ? 88 THR N CG2 1 ATOM 71 N N . LYS A 1 9 ? 62.809 21.354 155.018 1.00 3.86 ? 89 LYS N N 1 ATOM 72 C CA . LYS A 1 9 ? 63.079 22.695 154.538 1.00 3.95 ? 89 LYS N CA 1 ATOM 73 C C . LYS A 1 9 ? 62.042 23.220 153.518 1.00 4.69 ? 89 LYS N C 1 ATOM 74 O O . LYS A 1 9 ? 61.029 22.545 153.240 1.00 8.11 ? 89 LYS N O 1 ATOM 75 C CB . LYS A 1 9 ? 64.532 22.680 154.008 1.00 3.18 ? 89 LYS N CB 1 ATOM 76 C CG . LYS A 1 9 ? 65.572 22.498 155.163 1.00 4.88 ? 89 LYS N CG 1 ATOM 77 C CD . LYS A 1 9 ? 66.774 21.542 154.920 1.00 3.53 ? 89 LYS N CD 1 ATOM 78 C CE . LYS A 1 9 ? 67.680 22.126 153.834 1.00 3.13 ? 89 LYS N CE 1 ATOM 79 N NZ . LYS A 1 9 ? 68.643 21.176 153.291 1.00 2.12 ? 89 LYS N NZ 1 ATOM 80 N N . GLY A 1 10 ? 62.212 24.451 153.024 1.00 4.06 ? 90 GLY N N 1 ATOM 81 C CA . GLY A 1 10 ? 61.336 25.036 152.024 1.00 2.63 ? 90 GLY N CA 1 ATOM 82 C C . GLY A 1 10 ? 62.231 25.383 150.844 1.00 2.00 ? 90 GLY N C 1 ATOM 83 O O . GLY A 1 10 ? 63.451 25.221 150.957 1.00 2.49 ? 90 GLY N O 1 ATOM 84 N N . LEU A 1 11 ? 61.735 25.862 149.707 1.00 2.00 ? 91 LEU N N 1 ATOM 85 C CA . LEU A 1 11 ? 62.575 26.216 148.560 1.00 2.95 ? 91 LEU N CA 1 ATOM 86 C C . LEU A 1 11 ? 63.516 27.389 148.866 1.00 5.05 ? 91 LEU N C 1 ATOM 87 O O . LEU A 1 11 ? 63.331 28.063 149.878 1.00 8.47 ? 91 LEU N O 1 ATOM 88 C CB . LEU A 1 11 ? 61.677 26.576 147.389 1.00 2.01 ? 91 LEU N CB 1 ATOM 89 C CG . LEU A 1 11 ? 60.715 25.515 146.926 1.00 2.00 ? 91 LEU N CG 1 ATOM 90 C CD1 . LEU A 1 11 ? 59.656 26.128 146.053 1.00 2.00 ? 91 LEU N CD1 1 ATOM 91 C CD2 . LEU A 1 11 ? 61.465 24.473 146.155 1.00 4.60 ? 91 LEU N CD2 1 ATOM 92 N N . CYS A 1 12 ? 64.582 27.622 148.096 1.00 4.61 ? 92 CYS N N 1 ATOM 93 C CA . CYS A 1 12 ? 65.413 28.805 148.264 1.00 3.46 ? 92 CYS N CA 1 ATOM 94 C C . CYS A 1 12 ? 64.930 29.796 147.213 1.00 4.99 ? 92 CYS N C 1 ATOM 95 O O . CYS A 1 12 ? 64.138 29.447 146.338 1.00 6.62 ? 92 CYS N O 1 ATOM 96 C CB . CYS A 1 12 ? 66.874 28.557 148.000 1.00 3.72 ? 92 CYS N CB 1 ATOM 97 S SG . CYS A 1 12 ? 67.594 27.072 148.714 1.00 6.12 ? 92 CYS N SG 1 ATOM 98 N N . THR A 1 13 ? 65.376 31.050 147.247 1.00 4.83 ? 93 THR N N 1 ATOM 99 C CA . THR A 1 13 ? 64.911 32.080 146.336 1.00 4.28 ? 93 THR N CA 1 ATOM 100 C C . THR A 1 13 ? 65.438 31.762 144.979 1.00 4.70 ? 93 THR N C 1 ATOM 101 O O . THR A 1 13 ? 66.641 31.573 144.761 1.00 8.23 ? 93 THR N O 1 ATOM 102 C CB . THR A 1 13 ? 65.426 33.433 146.747 1.00 4.21 ? 93 THR N CB 1 ATOM 103 O OG1 . THR A 1 13 ? 65.639 33.401 148.173 1.00 8.40 ? 93 THR N OG1 1 ATOM 104 C CG2 . THR A 1 13 ? 64.427 34.523 146.385 1.00 2.05 ? 93 THR N CG2 1 ATOM 105 N N . ILE A 1 14 ? 64.531 31.640 144.045 1.00 3.79 ? 94 ILE N N 1 ATOM 106 C CA . ILE A 1 14 ? 64.978 31.366 142.711 1.00 3.06 ? 94 ILE N CA 1 ATOM 107 C C . ILE A 1 14 ? 65.285 32.742 142.174 1.00 4.66 ? 94 ILE N C 1 ATOM 108 O O . ILE A 1 14 ? 64.393 33.589 142.195 1.00 10.61 ? 94 ILE N O 1 ATOM 109 C CB . ILE A 1 14 ? 63.866 30.722 141.847 1.00 3.91 ? 94 ILE N CB 1 ATOM 110 C CG1 . ILE A 1 14 ? 62.942 29.671 142.501 1.00 4.42 ? 94 ILE N CG1 1 ATOM 111 C CG2 . ILE A 1 14 ? 64.651 30.126 140.728 1.00 6.88 ? 94 ILE N CG2 1 ATOM 112 C CD1 . ILE A 1 14 ? 63.596 28.432 143.062 1.00 4.45 ? 94 ILE N CD1 1 ATOM 113 N N . ASN A 1 15 ? 66.494 33.051 141.743 1.00 3.97 ? 95 ASN N N 1 ATOM 114 C CA . ASN A 1 15 ? 66.774 34.347 141.129 1.00 3.84 ? 95 ASN N CA 1 ATOM 115 C C . ASN A 1 15 ? 67.325 34.340 139.700 1.00 3.55 ? 95 ASN N C 1 ATOM 116 O O . ASN A 1 15 ? 67.400 35.379 139.022 1.00 3.27 ? 95 ASN N O 1 ATOM 117 C CB . ASN A 1 15 ? 67.733 35.106 141.947 1.00 4.69 ? 95 ASN N CB 1 ATOM 118 C CG . ASN A 1 15 ? 67.007 35.872 143.000 1.00 4.34 ? 95 ASN N CG 1 ATOM 119 O OD1 . ASN A 1 15 ? 67.340 35.821 144.171 1.00 2.06 ? 95 ASN N OD1 1 ATOM 120 N ND2 . ASN A 1 15 ? 65.952 36.570 142.646 1.00 5.76 ? 95 ASN N ND2 1 ATOM 121 N N . SER A 1 16 ? 67.810 33.164 139.284 1.00 3.29 ? 96 SER N N 1 ATOM 122 C CA . SER A 1 16 ? 68.261 32.829 137.939 1.00 4.25 ? 96 SER N CA 1 ATOM 123 C C . SER A 1 16 ? 68.466 31.328 137.964 1.00 7.24 ? 96 SER N C 1 ATOM 124 O O . SER A 1 16 ? 68.099 30.733 138.982 1.00 10.87 ? 96 SER N O 1 ATOM 125 C CB . SER A 1 16 ? 69.573 33.498 137.615 1.00 4.69 ? 96 SER N CB 1 ATOM 126 O OG . SER A 1 16 ? 70.607 33.192 138.533 1.00 3.04 ? 96 SER N OG 1 ATOM 127 N N . TRP A 1 17 ? 69.071 30.655 136.977 1.00 4.94 ? 97 TRP N N 1 ATOM 128 C CA . TRP A 1 17 ? 69.259 29.200 136.943 1.00 3.45 ? 97 TRP N CA 1 ATOM 129 C C . TRP A 1 17 ? 70.688 28.982 136.512 1.00 2.22 ? 97 TRP N C 1 ATOM 130 O O . TRP A 1 17 ? 71.180 29.845 135.788 1.00 4.37 ? 97 TRP N O 1 ATOM 131 C CB . TRP A 1 17 ? 68.346 28.588 135.946 1.00 2.00 ? 97 TRP N CB 1 ATOM 132 C CG . TRP A 1 17 ? 66.921 28.748 136.415 1.00 4.30 ? 97 TRP N CG 1 ATOM 133 C CD1 . TRP A 1 17 ? 66.232 29.867 136.060 1.00 6.97 ? 97 TRP N CD1 1 ATOM 134 C CD2 . TRP A 1 17 ? 66.189 27.913 137.221 1.00 3.85 ? 97 TRP N CD2 1 ATOM 135 N NE1 . TRP A 1 17 ? 65.071 29.768 136.642 1.00 7.31 ? 97 TRP N NE1 1 ATOM 136 C CE2 . TRP A 1 17 ? 65.007 28.620 137.327 1.00 4.94 ? 97 TRP N CE2 1 ATOM 137 C CE3 . TRP A 1 17 ? 66.294 26.717 137.878 1.00 4.75 ? 97 TRP N CE3 1 ATOM 138 C CZ2 . TRP A 1 17 ? 63.920 28.183 138.050 1.00 4.60 ? 97 TRP N CZ2 1 ATOM 139 C CZ3 . TRP A 1 17 ? 65.223 26.267 138.610 1.00 6.33 ? 97 TRP N CZ3 1 ATOM 140 C CH2 . TRP A 1 17 ? 64.043 26.983 138.702 1.00 7.54 ? 97 TRP N CH2 1 ATOM 141 N N . HIS A 1 18 ? 71.395 27.948 136.988 1.00 2.12 ? 98 HIS N N 1 ATOM 142 C CA . HIS A 1 18 ? 72.770 27.617 136.603 1.00 6.44 ? 98 HIS N CA 1 ATOM 143 C C . HIS A 1 18 ? 72.840 26.198 136.008 1.00 7.33 ? 98 HIS N C 1 ATOM 144 O O . HIS A 1 18 ? 72.011 25.388 136.443 1.00 10.07 ? 98 HIS N O 1 ATOM 145 C CB . HIS A 1 18 ? 73.686 27.744 137.852 1.00 5.63 ? 98 HIS N CB 1 ATOM 146 C CG . HIS A 1 18 ? 73.537 26.682 138.943 1.00 6.16 ? 98 HIS N CG 1 ATOM 147 N ND1 . HIS A 1 18 ? 74.141 25.494 138.954 1.00 8.60 ? 98 HIS N ND1 1 ATOM 148 C CD2 . HIS A 1 18 ? 72.757 26.766 140.090 1.00 7.06 ? 98 HIS N CD2 1 ATOM 149 C CE1 . HIS A 1 18 ? 73.760 24.879 140.062 1.00 9.65 ? 98 HIS N CE1 1 ATOM 150 N NE2 . HIS A 1 18 ? 72.927 25.642 140.746 1.00 9.32 ? 98 HIS N NE2 1 ATOM 151 N N . ILE A 1 19 ? 73.692 25.810 135.032 1.00 7.28 ? 99 ILE N N 1 ATOM 152 C CA . ILE A 1 19 ? 73.715 24.424 134.544 1.00 4.88 ? 99 ILE N CA 1 ATOM 153 C C . ILE A 1 19 ? 74.307 23.516 135.591 1.00 5.04 ? 99 ILE N C 1 ATOM 154 O O . ILE A 1 19 ? 75.372 23.712 136.195 1.00 4.22 ? 99 ILE N O 1 ATOM 155 C CB . ILE A 1 19 ? 74.587 24.015 133.326 1.00 2.97 ? 99 ILE N CB 1 ATOM 156 C CG1 . ILE A 1 19 ? 75.422 25.147 132.868 1.00 3.44 ? 99 ILE N CG1 1 ATOM 157 C CG2 . ILE A 1 19 ? 73.683 23.441 132.229 1.00 2.19 ? 99 ILE N CG2 1 ATOM 158 C CD1 . ILE A 1 19 ? 76.545 25.649 133.785 1.00 3.08 ? 99 ILE N CD1 1 ATOM 159 N N . TYR A 1 20 ? 73.476 22.484 135.701 1.00 4.23 ? 100 TYR N N 1 ATOM 160 C CA . TYR A 1 20 ? 73.679 21.397 136.594 1.00 4.12 ? 100 TYR N CA 1 ATOM 161 C C . TYR A 1 20 ? 74.181 20.257 135.749 1.00 4.61 ? 100 TYR N C 1 ATOM 162 O O . TYR A 1 20 ? 75.248 19.758 136.090 1.00 4.64 ? 100 TYR N O 1 ATOM 163 C CB . TYR A 1 20 ? 72.347 21.071 137.300 1.00 3.46 ? 100 TYR N CB 1 ATOM 164 C CG . TYR A 1 20 ? 72.520 20.015 138.378 1.00 3.67 ? 100 TYR N CG 1 ATOM 165 C CD1 . TYR A 1 20 ? 73.170 20.263 139.587 1.00 4.36 ? 100 TYR N CD1 1 ATOM 166 C CD2 . TYR A 1 20 ? 72.086 18.748 138.066 1.00 2.96 ? 100 TYR N CD2 1 ATOM 167 C CE1 . TYR A 1 20 ? 73.377 19.220 140.470 1.00 5.60 ? 100 TYR N CE1 1 ATOM 168 C CE2 . TYR A 1 20 ? 72.292 17.719 138.942 1.00 5.13 ? 100 TYR N CE2 1 ATOM 169 C CZ . TYR A 1 20 ? 72.937 17.954 140.124 1.00 5.12 ? 100 TYR N CZ 1 ATOM 170 O OH . TYR A 1 20 ? 73.110 16.854 140.921 1.00 8.65 ? 100 TYR N OH 1 ATOM 171 N N . GLY A 1 21 ? 73.559 19.792 134.676 1.00 6.76 ? 101 GLY N N 1 ATOM 172 C CA . GLY A 1 21 ? 74.109 18.647 133.969 1.00 9.10 ? 101 GLY N CA 1 ATOM 173 C C . GLY A 1 21 ? 73.789 18.693 132.495 1.00 8.22 ? 101 GLY N C 1 ATOM 174 O O . GLY A 1 21 ? 72.764 19.278 132.075 1.00 6.10 ? 101 GLY N O 1 ATOM 175 N N . LYS A 1 22 ? 74.683 18.129 131.700 1.00 9.38 ? 102 LYS N N 1 ATOM 176 C CA . LYS A 1 22 ? 74.416 18.068 130.291 1.00 9.91 ? 102 LYS N CA 1 ATOM 177 C C . LYS A 1 22 ? 75.142 16.813 129.868 1.00 12.25 ? 102 LYS N C 1 ATOM 178 O O . LYS A 1 22 ? 76.375 16.794 129.986 1.00 12.08 ? 102 LYS N O 1 ATOM 179 C CB . LYS A 1 22 ? 74.985 19.290 129.611 1.00 6.99 ? 102 LYS N CB 1 ATOM 180 C CG . LYS A 1 22 ? 74.350 19.410 128.256 1.00 5.98 ? 102 LYS N CG 1 ATOM 181 C CD . LYS A 1 22 ? 74.889 20.566 127.439 1.00 5.96 ? 102 LYS N CD 1 ATOM 182 C CE . LYS A 1 22 ? 74.159 20.651 126.109 1.00 6.36 ? 102 LYS N CE 1 ATOM 183 N NZ . LYS A 1 22 ? 74.321 19.433 125.353 1.00 7.93 ? 102 LYS N NZ 1 ATOM 184 N N . ASP A 1 23 ? 74.410 15.761 129.422 1.00 14.48 ? 103 ASP N N 1 ATOM 185 C CA . ASP A 1 23 ? 75.033 14.498 128.997 1.00 14.18 ? 103 ASP N CA 1 ATOM 186 C C . ASP A 1 23 ? 75.660 14.362 127.572 1.00 14.55 ? 103 ASP N C 1 ATOM 187 O O . ASP A 1 23 ? 76.566 13.553 127.316 1.00 16.27 ? 103 ASP N O 1 ATOM 188 C CB . ASP A 1 23 ? 73.976 13.402 129.248 1.00 15.94 ? 103 ASP N CB 1 ATOM 189 C CG . ASP A 1 23 ? 72.806 13.300 128.311 1.00 15.40 ? 103 ASP N CG 1 ATOM 190 O OD1 . ASP A 1 23 ? 72.562 14.168 127.506 1.00 23.68 ? 103 ASP N OD1 1 ATOM 191 O OD2 . ASP A 1 23 ? 72.118 12.310 128.379 1.00 16.19 ? 103 ASP N OD2 1 ATOM 192 N N . ASN A 1 24 ? 75.219 15.240 126.655 1.00 13.50 ? 104 ASN N N 1 ATOM 193 C CA . ASN A 1 24 ? 75.617 15.273 125.247 1.00 10.11 ? 104 ASN N CA 1 ATOM 194 C C . ASN A 1 24 ? 75.540 13.952 124.485 1.00 7.47 ? 104 ASN N C 1 ATOM 195 O O . ASN A 1 24 ? 76.203 13.720 123.468 1.00 11.39 ? 104 ASN N O 1 ATOM 196 C CB . ASN A 1 24 ? 77.031 15.788 125.113 1.00 12.44 ? 104 ASN N CB 1 ATOM 197 C CG . ASN A 1 24 ? 77.195 17.252 125.429 1.00 13.51 ? 104 ASN N CG 1 ATOM 198 O OD1 . ASN A 1 24 ? 76.619 18.103 124.771 1.00 20.62 ? 104 ASN N OD1 1 ATOM 199 N ND2 . ASN A 1 24 ? 77.974 17.571 126.461 1.00 7.03 ? 104 ASN N ND2 1 ATOM 200 N N . ALA A 1 25 ? 74.534 13.165 124.848 1.00 5.07 ? 105 ALA N N 1 ATOM 201 C CA . ALA A 1 25 ? 74.402 11.806 124.373 1.00 2.07 ? 105 ALA N CA 1 ATOM 202 C C . ALA A 1 25 ? 74.333 11.571 122.870 1.00 3.57 ? 105 ALA N C 1 ATOM 203 O O . ALA A 1 25 ? 75.130 10.754 122.424 1.00 8.14 ? 105 ALA N O 1 ATOM 204 C CB . ALA A 1 25 ? 73.192 11.201 125.059 1.00 2.00 ? 105 ALA N CB 1 ATOM 205 N N . VAL A 1 26 ? 73.478 12.259 122.076 1.00 3.93 ? 106 VAL N N 1 ATOM 206 C CA . VAL A 1 26 ? 73.401 12.096 120.619 1.00 2.02 ? 106 VAL N CA 1 ATOM 207 C C . VAL A 1 26 ? 74.707 12.549 120.017 1.00 2.00 ? 106 VAL N C 1 ATOM 208 O O . VAL A 1 26 ? 75.243 11.819 119.218 1.00 2.00 ? 106 VAL N O 1 ATOM 209 C CB . VAL A 1 26 ? 72.190 12.913 120.054 1.00 2.05 ? 106 VAL N CB 1 ATOM 210 C CG1 . VAL A 1 26 ? 72.161 13.047 118.552 1.00 2.00 ? 106 VAL N CG1 1 ATOM 211 C CG2 . VAL A 1 26 ? 70.926 12.097 120.308 1.00 2.07 ? 106 VAL N CG2 1 ATOM 212 N N . ARG A 1 27 ? 75.311 13.671 120.401 1.00 2.51 ? 107 ARG N N 1 ATOM 213 C CA . ARG A 1 27 ? 76.603 14.125 119.869 1.00 2.20 ? 107 ARG N CA 1 ATOM 214 C C . ARG A 1 27 ? 77.676 13.048 120.035 1.00 3.91 ? 107 ARG N C 1 ATOM 215 O O . ARG A 1 27 ? 78.349 12.653 119.072 1.00 5.78 ? 107 ARG N O 1 ATOM 216 C CB . ARG A 1 27 ? 77.085 15.365 120.602 1.00 2.09 ? 107 ARG N CB 1 ATOM 217 C CG . ARG A 1 27 ? 77.093 16.652 119.853 1.00 2.06 ? 107 ARG N CG 1 ATOM 218 C CD . ARG A 1 27 ? 77.390 17.758 120.800 1.00 2.69 ? 107 ARG N CD 1 ATOM 219 N NE . ARG A 1 27 ? 78.819 17.824 120.887 1.00 3.14 ? 107 ARG N NE 1 ATOM 220 C CZ . ARG A 1 27 ? 79.549 18.535 120.026 1.00 3.64 ? 107 ARG N CZ 1 ATOM 221 N NH1 . ARG A 1 27 ? 79.072 19.262 119.043 1.00 6.22 ? 107 ARG N NH1 1 ATOM 222 N NH2 . ARG A 1 27 ? 80.853 18.553 120.173 1.00 2.90 ? 107 ARG N NH2 1 ATOM 223 N N . ILE A 1 28 ? 77.807 12.487 121.248 1.00 3.52 ? 108 ILE N N 1 ATOM 224 C CA . ILE A 1 28 ? 78.805 11.452 121.487 1.00 5.34 ? 108 ILE N CA 1 ATOM 225 C C . ILE A 1 28 ? 78.455 10.153 120.741 1.00 6.22 ? 108 ILE N C 1 ATOM 226 O O . ILE A 1 28 ? 79.290 9.473 120.117 1.00 7.67 ? 108 ILE N O 1 ATOM 227 C CB . ILE A 1 28 ? 78.899 11.233 123.012 1.00 4.90 ? 108 ILE N CB 1 ATOM 228 C CG1 . ILE A 1 28 ? 79.349 12.532 123.634 1.00 2.07 ? 108 ILE N CG1 1 ATOM 229 C CG2 . ILE A 1 28 ? 79.895 10.121 123.368 1.00 3.27 ? 108 ILE N CG2 1 ATOM 230 C CD1 . ILE A 1 28 ? 79.181 12.423 125.154 1.00 2.00 ? 108 ILE N CD1 1 ATOM 231 N N . GLY A 1 29 ? 77.162 9.862 120.850 1.00 7.05 ? 109 GLY N N 1 ATOM 232 C CA . GLY A 1 29 ? 76.437 8.736 120.276 1.00 6.21 ? 109 GLY N CA 1 ATOM 233 C C . GLY A 1 29 ? 76.664 8.480 118.819 1.00 7.58 ? 109 GLY N C 1 ATOM 234 O O . GLY A 1 29 ? 76.453 7.358 118.407 1.00 8.90 ? 109 GLY N O 1 ATOM 235 N N . GLU A 1 30 ? 77.076 9.441 118.018 1.00 8.56 ? 110 GLU N N 1 ATOM 236 C CA . GLU A 1 30 ? 77.429 9.195 116.639 1.00 10.94 ? 110 GLU N CA 1 ATOM 237 C C . GLU A 1 30 ? 78.611 8.264 116.591 1.00 12.28 ? 110 GLU N C 1 ATOM 238 O O . GLU A 1 30 ? 78.849 7.711 115.531 1.00 13.04 ? 110 GLU N O 1 ATOM 239 C CB . GLU A 1 30 ? 77.788 10.490 115.942 1.00 10.77 ? 110 GLU N CB 1 ATOM 240 C CG . GLU A 1 30 ? 77.893 10.517 114.408 1.00 8.33 ? 110 GLU N CG 1 ATOM 241 C CD . GLU A 1 30 ? 79.198 10.000 113.792 1.00 5.75 ? 110 GLU N CD 1 ATOM 242 O OE1 . GLU A 1 30 ? 80.235 10.222 114.403 1.00 5.99 ? 110 GLU N OE1 1 ATOM 243 O OE2 . GLU A 1 30 ? 79.196 9.344 112.745 1.00 7.23 ? 110 GLU N OE2 1 ATOM 244 N N . ASP A 1 31 ? 79.385 8.016 117.651 1.00 14.48 ? 111 ASP N N 1 ATOM 245 C CA . ASP A 1 31 ? 80.513 7.108 117.564 1.00 14.81 ? 111 ASP N CA 1 ATOM 246 C C . ASP A 1 31 ? 80.725 6.265 118.827 1.00 13.56 ? 111 ASP N C 1 ATOM 247 O O . ASP A 1 31 ? 81.727 5.541 118.905 1.00 22.01 ? 111 ASP N O 1 ATOM 248 C CB . ASP A 1 31 ? 81.753 7.935 117.237 1.00 16.34 ? 111 ASP N CB 1 ATOM 249 C CG . ASP A 1 31 ? 82.987 7.168 116.734 1.00 19.61 ? 111 ASP N CG 1 ATOM 250 O OD1 . ASP A 1 31 ? 82.902 6.586 115.643 1.00 17.63 ? 111 ASP N OD1 1 ATOM 251 O OD2 . ASP A 1 31 ? 84.029 7.197 117.422 1.00 23.96 ? 111 ASP N OD2 1 ATOM 252 N N . SER A 1 32 ? 79.865 6.217 119.850 1.00 9.95 ? 112 SER N N 1 ATOM 253 C CA . SER A 1 32 ? 80.110 5.315 120.980 1.00 7.68 ? 112 SER N CA 1 ATOM 254 C C . SER A 1 32 ? 78.887 4.424 121.106 1.00 7.16 ? 112 SER N C 1 ATOM 255 O O . SER A 1 32 ? 77.993 4.473 120.242 1.00 9.38 ? 112 SER N O 1 ATOM 256 C CB . SER A 1 32 ? 80.309 6.107 122.248 1.00 8.07 ? 112 SER N CB 1 ATOM 257 O OG . SER A 1 32 ? 81.434 6.907 122.012 1.00 15.42 ? 112 SER N OG 1 ATOM 258 N N . ASP A 1 33 ? 78.824 3.550 122.115 1.00 6.45 ? 113 ASP N N 1 ATOM 259 C CA . ASP A 1 33 ? 77.647 2.727 122.275 1.00 3.11 ? 113 ASP N CA 1 ATOM 260 C C . ASP A 1 33 ? 76.710 3.301 123.327 1.00 2.27 ? 113 ASP N C 1 ATOM 261 O O . ASP A 1 33 ? 76.555 2.770 124.413 1.00 2.00 ? 113 ASP N O 1 ATOM 262 C CB . ASP A 1 33 ? 78.166 1.297 122.579 1.00 4.83 ? 113 ASP N CB 1 ATOM 263 C CG . ASP A 1 33 ? 79.044 0.772 121.439 1.00 5.41 ? 113 ASP N CG 1 ATOM 264 O OD1 . ASP A 1 33 ? 78.665 0.898 120.264 1.00 5.62 ? 113 ASP N OD1 1 ATOM 265 O OD2 . ASP A 1 33 ? 80.115 0.256 121.720 1.00 4.93 ? 113 ASP N OD2 1 ATOM 266 N N . VAL A 1 34 ? 76.166 4.453 122.904 1.00 2.00 ? 114 VAL N N 1 ATOM 267 C CA . VAL A 1 34 ? 75.148 5.233 123.556 1.00 2.00 ? 114 VAL N CA 1 ATOM 268 C C . VAL A 1 34 ? 73.815 4.614 123.172 1.00 2.09 ? 114 VAL N C 1 ATOM 269 O O . VAL A 1 34 ? 73.599 4.213 122.023 1.00 5.31 ? 114 VAL N O 1 ATOM 270 C CB . VAL A 1 34 ? 75.185 6.636 123.066 1.00 2.00 ? 114 VAL N CB 1 ATOM 271 C CG1 . VAL A 1 34 ? 74.201 7.509 123.789 1.00 2.00 ? 114 VAL N CG1 1 ATOM 272 C CG2 . VAL A 1 34 ? 76.562 7.160 123.338 1.00 2.03 ? 114 VAL N CG2 1 ATOM 273 N N . LEU A 1 35 ? 72.900 4.501 124.146 1.00 3.15 ? 115 LEU N N 1 ATOM 274 C CA . LEU A 1 35 ? 71.673 3.760 123.991 1.00 2.37 ? 115 LEU N CA 1 ATOM 275 C C . LEU A 1 35 ? 70.596 4.683 123.532 1.00 2.00 ? 115 LEU N C 1 ATOM 276 O O . LEU A 1 35 ? 70.613 5.867 123.864 1.00 2.90 ? 115 LEU N O 1 ATOM 277 C CB . LEU A 1 35 ? 71.245 3.126 125.313 1.00 2.00 ? 115 LEU N CB 1 ATOM 278 C CG . LEU A 1 35 ? 71.993 1.976 125.924 1.00 2.41 ? 115 LEU N CG 1 ATOM 279 C CD1 . LEU A 1 35 ? 71.489 1.757 127.307 1.00 5.84 ? 115 LEU N CD1 1 ATOM 280 C CD2 . LEU A 1 35 ? 71.782 0.733 125.141 1.00 2.00 ? 115 LEU N CD2 1 ATOM 281 N N . VAL A 1 36 ? 69.640 4.166 122.785 1.00 2.00 ? 116 VAL N N 1 ATOM 282 C CA . VAL A 1 36 ? 68.561 5.004 122.338 1.00 2.00 ? 116 VAL N CA 1 ATOM 283 C C . VAL A 1 36 ? 67.664 5.028 123.580 1.00 3.69 ? 116 VAL N C 1 ATOM 284 O O . VAL A 1 36 ? 67.469 4.007 124.262 1.00 5.10 ? 116 VAL N O 1 ATOM 285 C CB . VAL A 1 36 ? 67.829 4.373 121.151 1.00 2.00 ? 116 VAL N CB 1 ATOM 286 C CG1 . VAL A 1 36 ? 66.833 5.363 120.643 1.00 2.44 ? 116 VAL N CG1 1 ATOM 287 C CG2 . VAL A 1 36 ? 68.740 4.089 119.989 1.00 2.93 ? 116 VAL N CG2 1 ATOM 288 N N . THR A 1 37 ? 67.202 6.213 123.969 1.00 4.66 ? 117 THR N N 1 ATOM 289 C CA . THR A 1 37 ? 66.311 6.378 125.091 1.00 4.66 ? 117 THR N CA 1 ATOM 290 C C . THR A 1 37 ? 65.288 7.438 124.705 1.00 3.40 ? 117 THR N C 1 ATOM 291 O O . THR A 1 37 ? 65.214 7.905 123.572 1.00 3.97 ? 117 THR N O 1 ATOM 292 C CB . THR A 1 37 ? 67.100 6.820 126.329 1.00 7.54 ? 117 THR N CB 1 ATOM 293 O OG1 . THR A 1 37 ? 67.737 8.030 125.989 1.00 10.68 ? 117 THR N OG1 1 ATOM 294 C CG2 . THR A 1 37 ? 68.137 5.821 126.758 1.00 6.47 ? 117 THR N CG2 1 ATOM 295 N N . ARG A 1 38 ? 64.451 7.781 125.660 1.00 3.56 ? 118 ARG N N 1 ATOM 296 C CA . ARG A 1 38 ? 63.428 8.811 125.608 1.00 6.00 ? 118 ARG N CA 1 ATOM 297 C C . ARG A 1 38 ? 62.753 8.705 126.995 1.00 7.69 ? 118 ARG N C 1 ATOM 298 O O . ARG A 1 38 ? 62.818 7.698 127.718 1.00 13.44 ? 118 ARG N O 1 ATOM 299 C CB . ARG A 1 38 ? 62.388 8.544 124.499 1.00 6.91 ? 118 ARG N CB 1 ATOM 300 C CG . ARG A 1 38 ? 62.016 9.568 123.409 1.00 7.14 ? 118 ARG N CG 1 ATOM 301 C CD . ARG A 1 38 ? 61.424 10.832 123.978 1.00 8.73 ? 118 ARG N CD 1 ATOM 302 N NE . ARG A 1 38 ? 60.183 11.288 123.375 1.00 6.91 ? 118 ARG N NE 1 ATOM 303 C CZ . ARG A 1 38 ? 59.354 12.083 124.063 1.00 8.86 ? 118 ARG N CZ 1 ATOM 304 N NH1 . ARG A 1 38 ? 59.580 12.518 125.297 1.00 11.37 ? 118 ARG N NH1 1 ATOM 305 N NH2 . ARG A 1 38 ? 58.225 12.473 123.533 1.00 10.09 ? 118 ARG N NH2 1 ATOM 306 N N . GLU A 1 39 ? 62.090 9.808 127.344 1.00 5.43 ? 119 GLU N N 1 ATOM 307 C CA . GLU A 1 39 ? 61.476 10.096 128.631 1.00 4.30 ? 119 GLU N CA 1 ATOM 308 C C . GLU A 1 39 ? 62.574 9.957 129.662 1.00 3.54 ? 119 GLU N C 1 ATOM 309 O O . GLU A 1 39 ? 62.798 8.883 130.202 1.00 3.71 ? 119 GLU N O 1 ATOM 310 C CB . GLU A 1 39 ? 60.316 9.137 128.978 1.00 6.27 ? 119 GLU N CB 1 ATOM 311 C CG . GLU A 1 39 ? 59.176 9.019 127.953 1.00 7.68 ? 119 GLU N CG 1 ATOM 312 C CD . GLU A 1 39 ? 59.540 8.127 126.768 1.00 9.77 ? 119 GLU N CD 1 ATOM 313 O OE1 . GLU A 1 39 ? 60.196 7.100 126.954 1.00 13.68 ? 119 GLU N OE1 1 ATOM 314 O OE2 . GLU A 1 39 ? 59.197 8.484 125.643 1.00 9.18 ? 119 GLU N OE2 1 ATOM 315 N N . PRO A 1 40 ? 63.402 10.969 129.875 1.00 2.44 ? 120 PRO N N 1 ATOM 316 C CA . PRO A 1 40 ? 64.446 10.932 130.849 1.00 3.63 ? 120 PRO N CA 1 ATOM 317 C C . PRO A 1 40 ? 63.922 11.562 132.113 1.00 5.41 ? 120 PRO N C 1 ATOM 318 O O . PRO A 1 40 ? 62.754 11.916 132.113 1.00 10.40 ? 120 PRO N O 1 ATOM 319 C CB . PRO A 1 40 ? 65.577 11.684 130.172 1.00 2.00 ? 120 PRO N CB 1 ATOM 320 C CG . PRO A 1 40 ? 64.889 12.821 129.520 1.00 2.00 ? 120 PRO N CG 1 ATOM 321 C CD . PRO A 1 40 ? 63.541 12.217 129.137 1.00 2.00 ? 120 PRO N CD 1 ATOM 322 N N . TYR A 1 41 ? 64.734 11.686 133.164 1.00 4.30 ? 121 TYR N N 1 ATOM 323 C CA . TYR A 1 41 ? 64.469 12.428 134.365 1.00 2.04 ? 121 TYR N CA 1 ATOM 324 C C . TYR A 1 41 ? 65.700 12.260 135.232 1.00 3.58 ? 121 TYR N C 1 ATOM 325 O O . TYR A 1 41 ? 66.619 11.584 134.791 1.00 3.69 ? 121 TYR N O 1 ATOM 326 C CB . TYR A 1 41 ? 63.172 11.941 135.096 1.00 2.33 ? 121 TYR N CB 1 ATOM 327 C CG . TYR A 1 41 ? 62.988 10.499 135.550 1.00 2.86 ? 121 TYR N CG 1 ATOM 328 C CD1 . TYR A 1 41 ? 63.468 10.122 136.785 1.00 2.19 ? 121 TYR N CD1 1 ATOM 329 C CD2 . TYR A 1 41 ? 62.345 9.562 134.790 1.00 2.46 ? 121 TYR N CD2 1 ATOM 330 C CE1 . TYR A 1 41 ? 63.312 8.855 137.292 1.00 2.00 ? 121 TYR N CE1 1 ATOM 331 C CE2 . TYR A 1 41 ? 62.181 8.286 135.290 1.00 3.12 ? 121 TYR N CE2 1 ATOM 332 C CZ . TYR A 1 41 ? 62.670 7.960 136.518 1.00 2.00 ? 121 TYR N CZ 1 ATOM 333 O OH . TYR A 1 41 ? 62.522 6.719 137.024 1.00 3.31 ? 121 TYR N OH 1 ATOM 334 N N . VAL A 1 42 ? 65.802 12.882 136.414 1.00 4.47 ? 122 VAL N N 1 ATOM 335 C CA . VAL A 1 42 ? 66.975 12.820 137.268 1.00 5.37 ? 122 VAL N CA 1 ATOM 336 C C . VAL A 1 42 ? 66.541 12.553 138.711 1.00 7.50 ? 122 VAL N C 1 ATOM 337 O O . VAL A 1 42 ? 65.483 13.037 139.108 1.00 7.84 ? 122 VAL N O 1 ATOM 338 C CB . VAL A 1 42 ? 67.735 14.149 137.176 1.00 4.23 ? 122 VAL N CB 1 ATOM 339 C CG1 . VAL A 1 42 ? 68.904 14.109 138.194 1.00 2.36 ? 122 VAL N CG1 1 ATOM 340 C CG2 . VAL A 1 42 ? 68.188 14.412 135.752 1.00 2.03 ? 122 VAL N CG2 1 ATOM 341 N N . SER A 1 43 ? 67.301 11.829 139.541 1.00 9.04 ? 123 SER N N 1 ATOM 342 C CA . SER A 1 43 ? 66.883 11.558 140.902 1.00 7.75 ? 123 SER N CA 1 ATOM 343 C C . SER A 1 43 ? 68.108 11.365 141.738 1.00 8.60 ? 123 SER N C 1 ATOM 344 O O . SER A 1 43 ? 69.150 10.820 141.318 1.00 9.70 ? 123 SER N O 1 ATOM 345 C CB . SER A 1 43 ? 66.044 10.304 140.979 1.00 7.90 ? 123 SER N CB 1 ATOM 346 O OG . SER A 1 43 ? 65.552 10.027 142.271 1.00 10.62 ? 123 SER N OG 1 ATOM 347 N N . CYS A 1 44 ? 67.900 11.781 142.979 1.00 10.93 ? 124 CYS N N 1 ATOM 348 C CA . CYS A 1 44 ? 69.026 11.801 143.862 1.00 9.50 ? 124 CYS N CA 1 ATOM 349 C C . CYS A 1 44 ? 68.924 10.820 145.004 1.00 8.01 ? 124 CYS N C 1 ATOM 350 O O . CYS A 1 44 ? 67.840 10.608 145.544 1.00 9.84 ? 124 CYS N O 1 ATOM 351 C CB . CYS A 1 44 ? 69.209 13.204 144.389 1.00 10.15 ? 124 CYS N CB 1 ATOM 352 S SG . CYS A 1 44 ? 69.766 14.409 143.170 1.00 10.01 ? 124 CYS N SG 1 ATOM 353 N N . ASP A 1 45 ? 70.034 10.113 145.171 1.00 7.07 ? 125 ASP N N 1 ATOM 354 C CA . ASP A 1 45 ? 70.269 9.271 146.310 1.00 6.17 ? 125 ASP N CA 1 ATOM 355 C C . ASP A 1 45 ? 70.846 10.189 147.360 1.00 9.26 ? 125 ASP N C 1 ATOM 356 O O . ASP A 1 45 ? 71.440 11.223 147.043 1.00 8.52 ? 125 ASP N O 1 ATOM 357 C CB . ASP A 1 45 ? 71.308 8.232 146.060 1.00 8.82 ? 125 ASP N CB 1 ATOM 358 C CG . ASP A 1 45 ? 70.931 6.970 145.299 1.00 11.95 ? 125 ASP N CG 1 ATOM 359 O OD1 . ASP A 1 45 ? 69.835 6.870 144.735 1.00 17.04 ? 125 ASP N OD1 1 ATOM 360 O OD2 . ASP A 1 45 ? 71.757 6.059 145.262 1.00 13.78 ? 125 ASP N OD2 1 ATOM 361 N N . PRO A 1 46 ? 70.834 9.852 148.644 1.00 10.97 ? 126 PRO N N 1 ATOM 362 C CA . PRO A 1 46 ? 71.532 10.595 149.690 1.00 11.94 ? 126 PRO N CA 1 ATOM 363 C C . PRO A 1 46 ? 73.044 10.743 149.537 1.00 13.39 ? 126 PRO N C 1 ATOM 364 O O . PRO A 1 46 ? 73.698 11.549 150.198 1.00 13.65 ? 126 PRO N O 1 ATOM 365 C CB . PRO A 1 46 ? 71.121 9.868 150.936 1.00 10.76 ? 126 PRO N CB 1 ATOM 366 C CG . PRO A 1 46 ? 70.726 8.500 150.446 1.00 10.18 ? 126 PRO N CG 1 ATOM 367 C CD . PRO A 1 46 ? 69.963 8.867 149.225 1.00 10.52 ? 126 PRO N CD 1 ATOM 368 N N . ASP A 1 47 ? 73.554 9.959 148.590 1.00 16.08 ? 127 ASP N N 1 ATOM 369 C CA . ASP A 1 47 ? 74.950 9.797 148.347 1.00 19.89 ? 127 ASP N CA 1 ATOM 370 C C . ASP A 1 47 ? 75.388 10.215 146.943 1.00 19.97 ? 127 ASP N C 1 ATOM 371 O O . ASP A 1 47 ? 76.593 10.403 146.805 1.00 21.15 ? 127 ASP N O 1 ATOM 372 C CB . ASP A 1 47 ? 75.128 8.336 148.697 1.00 23.82 ? 127 ASP N CB 1 ATOM 373 C CG . ASP A 1 47 ? 76.286 7.595 148.055 1.00 28.33 ? 127 ASP N CG 1 ATOM 374 O OD1 . ASP A 1 47 ? 77.437 7.882 148.405 1.00 29.89 ? 127 ASP N OD1 1 ATOM 375 O OD2 . ASP A 1 47 ? 76.027 6.722 147.212 1.00 32.95 ? 127 ASP N OD2 1 ATOM 376 N N . GLU A 1 48 ? 74.515 10.370 145.900 1.00 20.72 ? 128 GLU N N 1 ATOM 377 C CA . GLU A 1 48 ? 74.881 10.729 144.510 1.00 18.69 ? 128 GLU N CA 1 ATOM 378 C C . GLU A 1 48 ? 73.689 11.089 143.595 1.00 18.29 ? 128 GLU N C 1 ATOM 379 O O . GLU A 1 48 ? 72.597 10.627 143.927 1.00 21.07 ? 128 GLU N O 1 ATOM 380 C CB . GLU A 1 48 ? 75.659 9.587 143.812 1.00 20.13 ? 128 GLU N CB 1 ATOM 381 C CG . GLU A 1 48 ? 75.054 8.201 143.560 1.00 20.48 ? 128 GLU N CG 1 ATOM 382 C CD . GLU A 1 48 ? 75.674 7.465 142.365 1.00 22.93 ? 128 GLU N CD 1 ATOM 383 O OE1 . GLU A 1 48 ? 75.798 8.062 141.287 1.00 22.59 ? 128 GLU N OE1 1 ATOM 384 O OE2 . GLU A 1 48 ? 76.019 6.287 142.500 1.00 25.74 ? 128 GLU N OE2 1 ATOM 385 N N . CYS A 1 49 ? 73.740 11.861 142.483 1.00 13.82 ? 129 CYS N N 1 ATOM 386 C CA . CYS A 1 49 ? 72.559 12.074 141.641 1.00 9.84 ? 129 CYS N CA 1 ATOM 387 C C . CYS A 1 49 ? 72.778 11.404 140.301 1.00 7.21 ? 129 CYS N C 1 ATOM 388 O O . CYS A 1 49 ? 73.891 11.443 139.801 1.00 3.29 ? 129 CYS N O 1 ATOM 389 C CB . CYS A 1 49 ? 72.284 13.539 141.384 1.00 9.83 ? 129 CYS N CB 1 ATOM 390 S SG . CYS A 1 49 ? 71.755 14.338 142.929 1.00 11.35 ? 129 CYS N SG 1 ATOM 391 N N . ARG A 1 50 ? 71.826 10.736 139.686 1.00 5.24 ? 130 ARG N N 1 ATOM 392 C CA . ARG A 1 50 ? 72.057 10.029 138.455 1.00 4.88 ? 130 ARG N CA 1 ATOM 393 C C . ARG A 1 50 ? 71.016 10.421 137.406 1.00 4.91 ? 130 ARG N C 1 ATOM 394 O O . ARG A 1 50 ? 69.989 11.014 137.775 1.00 3.46 ? 130 ARG N O 1 ATOM 395 C CB . ARG A 1 50 ? 71.965 8.575 138.752 1.00 5.43 ? 130 ARG N CB 1 ATOM 396 C CG . ARG A 1 50 ? 73.099 8.071 139.602 1.00 4.66 ? 130 ARG N CG 1 ATOM 397 C CD . ARG A 1 50 ? 72.864 6.644 140.013 1.00 5.14 ? 130 ARG N CD 1 ATOM 398 N NE . ARG A 1 50 ? 72.944 5.694 138.920 1.00 5.02 ? 130 ARG N NE 1 ATOM 399 C CZ . ARG A 1 50 ? 74.073 5.022 138.669 1.00 3.22 ? 130 ARG N CZ 1 ATOM 400 N NH1 . ARG A 1 50 ? 75.245 5.327 139.251 1.00 2.03 ? 130 ARG N NH1 1 ATOM 401 N NH2 . ARG A 1 50 ? 74.074 4.070 137.742 1.00 4.51 ? 130 ARG N NH2 1 ATOM 402 N N . PHE A 1 51 ? 71.202 10.121 136.114 1.00 4.39 ? 131 PHE N N 1 ATOM 403 C CA . PHE A 1 51 ? 70.208 10.421 135.094 1.00 2.04 ? 131 PHE N CA 1 ATOM 404 C C . PHE A 1 51 ? 69.457 9.112 134.893 1.00 2.00 ? 131 PHE N C 1 ATOM 405 O O . PHE A 1 51 ? 70.062 8.029 134.918 1.00 2.03 ? 131 PHE N O 1 ATOM 406 C CB . PHE A 1 51 ? 70.851 10.847 133.767 1.00 4.01 ? 131 PHE N CB 1 ATOM 407 C CG . PHE A 1 51 ? 71.437 12.242 133.706 1.00 4.51 ? 131 PHE N CG 1 ATOM 408 C CD1 . PHE A 1 51 ? 71.219 13.144 134.723 1.00 3.83 ? 131 PHE N CD1 1 ATOM 409 C CD2 . PHE A 1 51 ? 72.144 12.612 132.590 1.00 3.91 ? 131 PHE N CD2 1 ATOM 410 C CE1 . PHE A 1 51 ? 71.733 14.418 134.605 1.00 2.04 ? 131 PHE N CE1 1 ATOM 411 C CE2 . PHE A 1 51 ? 72.667 13.873 132.481 1.00 3.87 ? 131 PHE N CE2 1 ATOM 412 C CZ . PHE A 1 51 ? 72.449 14.791 133.485 1.00 2.03 ? 131 PHE N CZ 1 ATOM 413 N N . TYR A 1 52 ? 68.128 9.149 134.795 1.00 2.42 ? 132 TYR N N 1 ATOM 414 C CA . TYR A 1 52 ? 67.327 7.936 134.592 1.00 2.04 ? 132 TYR N CA 1 ATOM 415 C C . TYR A 1 52 ? 66.612 8.100 133.305 1.00 2.00 ? 132 TYR N C 1 ATOM 416 O O . TYR A 1 52 ? 66.250 9.239 133.040 1.00 2.74 ? 132 TYR N O 1 ATOM 417 C CB . TYR A 1 52 ? 66.222 7.727 135.592 1.00 2.00 ? 132 TYR N CB 1 ATOM 418 C CG . TYR A 1 52 ? 66.727 7.412 136.968 1.00 2.00 ? 132 TYR N CG 1 ATOM 419 C CD1 . TYR A 1 52 ? 67.523 8.335 137.589 1.00 4.06 ? 132 TYR N CD1 1 ATOM 420 C CD2 . TYR A 1 52 ? 66.416 6.205 137.540 1.00 2.02 ? 132 TYR N CD2 1 ATOM 421 C CE1 . TYR A 1 52 ? 68.035 8.037 138.817 1.00 4.57 ? 132 TYR N CE1 1 ATOM 422 C CE2 . TYR A 1 52 ? 66.931 5.906 138.771 1.00 3.85 ? 132 TYR N CE2 1 ATOM 423 C CZ . TYR A 1 52 ? 67.750 6.823 139.396 1.00 4.93 ? 132 TYR N CZ 1 ATOM 424 O OH . TYR A 1 52 ? 68.347 6.529 140.607 1.00 8.82 ? 132 TYR N OH 1 ATOM 425 N N . ALA A 1 53 ? 66.324 7.056 132.551 1.00 2.00 ? 133 ALA N N 1 ATOM 426 C CA . ALA A 1 53 ? 65.619 7.225 131.308 1.00 2.04 ? 133 ALA N CA 1 ATOM 427 C C . ALA A 1 53 ? 65.050 5.901 130.886 1.00 3.44 ? 133 ALA N C 1 ATOM 428 O O . ALA A 1 53 ? 65.481 4.880 131.414 1.00 5.37 ? 133 ALA N O 1 ATOM 429 C CB . ALA A 1 53 ? 66.539 7.726 130.191 1.00 2.01 ? 133 ALA N CB 1 ATOM 430 N N . LEU A 1 54 ? 64.101 5.891 129.941 1.00 3.78 ? 134 LEU N N 1 ATOM 431 C CA . LEU A 1 54 ? 63.468 4.687 129.445 1.00 4.10 ? 134 LEU N CA 1 ATOM 432 C C . LEU A 1 54 ? 64.247 4.298 128.182 1.00 5.76 ? 134 LEU N C 1 ATOM 433 O O . LEU A 1 54 ? 64.222 5.033 127.190 1.00 9.69 ? 134 LEU N O 1 ATOM 434 C CB . LEU A 1 54 ? 62.042 5.072 129.188 1.00 2.44 ? 134 LEU N CB 1 ATOM 435 C CG . LEU A 1 54 ? 60.908 4.378 129.876 1.00 2.00 ? 134 LEU N CG 1 ATOM 436 C CD1 . LEU A 1 54 ? 61.389 3.549 131.006 1.00 2.00 ? 134 LEU N CD1 1 ATOM 437 C CD2 . LEU A 1 54 ? 59.929 5.424 130.358 1.00 2.00 ? 134 LEU N CD2 1 ATOM 438 N N . SER A 1 55 ? 65.048 3.223 128.251 1.00 3.99 ? 135 SER N N 1 ATOM 439 C CA . SER A 1 55 ? 65.830 2.696 127.141 1.00 3.34 ? 135 SER N CA 1 ATOM 440 C C . SER A 1 55 ? 64.978 1.987 126.115 1.00 4.35 ? 135 SER N C 1 ATOM 441 O O . SER A 1 55 ? 63.970 1.393 126.470 1.00 8.21 ? 135 SER N O 1 ATOM 442 C CB . SER A 1 55 ? 66.879 1.685 127.622 1.00 2.07 ? 135 SER N CB 1 ATOM 443 O OG . SER A 1 55 ? 67.659 1.146 126.539 1.00 4.34 ? 135 SER N OG 1 ATOM 444 N N . GLN A 1 56 ? 65.381 1.957 124.857 1.00 5.34 ? 136 GLN N N 1 ATOM 445 C CA . GLN A 1 56 ? 64.611 1.268 123.830 1.00 4.75 ? 136 GLN N CA 1 ATOM 446 C C . GLN A 1 56 ? 65.328 0.017 123.421 1.00 3.40 ? 136 GLN N C 1 ATOM 447 O O . GLN A 1 56 ? 64.940 -0.612 122.447 1.00 4.79 ? 136 GLN N O 1 ATOM 448 C CB . GLN A 1 56 ? 64.430 2.033 122.541 1.00 4.19 ? 136 GLN N CB 1 ATOM 449 C CG . GLN A 1 56 ? 63.539 3.227 122.638 1.00 4.10 ? 136 GLN N CG 1 ATOM 450 C CD . GLN A 1 56 ? 62.046 3.083 122.389 1.00 5.90 ? 136 GLN N CD 1 ATOM 451 O OE1 . GLN A 1 56 ? 61.476 4.154 122.259 1.00 8.55 ? 136 GLN N OE1 1 ATOM 452 N NE2 . GLN A 1 56 ? 61.257 2.028 122.187 1.00 5.80 ? 136 GLN N NE2 1 ATOM 453 N N . GLY A 1 57 ? 66.425 -0.299 124.088 1.00 2.09 ? 137 GLY N N 1 ATOM 454 C CA . GLY A 1 57 ? 67.142 -1.524 123.820 1.00 2.56 ? 137 GLY N CA 1 ATOM 455 C C . GLY A 1 57 ? 67.793 -1.634 122.462 1.00 3.39 ? 137 GLY N C 1 ATOM 456 O O . GLY A 1 57 ? 67.565 -2.577 121.709 1.00 3.87 ? 137 GLY N O 1 ATOM 457 N N . THR A 1 58 ? 68.597 -0.635 122.153 1.00 6.45 ? 138 THR N N 1 ATOM 458 C CA . THR A 1 58 ? 69.375 -0.623 120.943 1.00 9.13 ? 138 THR N CA 1 ATOM 459 C C . THR A 1 58 ? 70.344 0.550 121.074 1.00 9.29 ? 138 THR N C 1 ATOM 460 O O . THR A 1 58 ? 70.115 1.442 121.900 1.00 7.25 ? 138 THR N O 1 ATOM 461 C CB . THR A 1 58 ? 68.420 -0.486 119.747 1.00 12.95 ? 138 THR N CB 1 ATOM 462 O OG1 . THR A 1 58 ? 69.256 -0.611 118.622 1.00 18.77 ? 138 THR N OG1 1 ATOM 463 C CG2 . THR A 1 58 ? 67.614 0.771 119.732 1.00 12.92 ? 138 THR N CG2 1 ATOM 464 N N . THR A 1 59 ? 71.487 0.516 120.379 1.00 7.09 ? 139 THR N N 1 ATOM 465 C CA . THR A 1 59 ? 72.417 1.638 120.355 1.00 4.03 ? 139 THR N CA 1 ATOM 466 C C . THR A 1 59 ? 71.876 2.623 119.282 1.00 5.29 ? 139 THR N C 1 ATOM 467 O O . THR A 1 59 ? 71.119 2.187 118.401 1.00 8.49 ? 139 THR N O 1 ATOM 468 C CB . THR A 1 59 ? 73.839 1.051 120.025 1.00 3.48 ? 139 THR N CB 1 ATOM 469 O OG1 . THR A 1 59 ? 73.782 0.226 118.864 1.00 2.83 ? 139 THR N OG1 1 ATOM 470 C CG2 . THR A 1 59 ? 74.341 0.187 121.149 1.00 2.31 ? 139 THR N CG2 1 ATOM 471 N N . ILE A 1 60 ? 72.140 3.937 119.273 1.00 5.11 ? 140 ILE N N 1 ATOM 472 C CA . ILE A 1 60 ? 71.588 4.822 118.239 1.00 4.33 ? 140 ILE N CA 1 ATOM 473 C C . ILE A 1 60 ? 72.133 4.361 116.898 1.00 5.10 ? 140 ILE N C 1 ATOM 474 O O . ILE A 1 60 ? 71.299 4.264 116.006 1.00 7.15 ? 140 ILE N O 1 ATOM 475 C CB . ILE A 1 60 ? 71.930 6.374 118.362 1.00 4.83 ? 140 ILE N CB 1 ATOM 476 C CG1 . ILE A 1 60 ? 72.594 6.728 119.653 1.00 5.31 ? 140 ILE N CG1 1 ATOM 477 C CG2 . ILE A 1 60 ? 70.617 7.183 118.352 1.00 2.00 ? 140 ILE N CG2 1 ATOM 478 C CD1 . ILE A 1 60 ? 73.000 8.191 119.544 1.00 8.74 ? 140 ILE N CD1 1 ATOM 479 N N . ARG A 1 61 ? 73.427 4.051 116.662 1.00 4.50 ? 141 ARG N N 1 ATOM 480 C CA . ARG A 1 61 ? 73.931 3.511 115.384 1.00 3.23 ? 141 ARG N CA 1 ATOM 481 C C . ARG A 1 61 ? 73.399 2.112 115.078 1.00 2.62 ? 141 ARG N C 1 ATOM 482 O O . ARG A 1 61 ? 73.179 1.797 113.903 1.00 4.76 ? 141 ARG N O 1 ATOM 483 C CB . ARG A 1 61 ? 75.451 3.438 115.397 1.00 2.06 ? 141 ARG N CB 1 ATOM 484 C CG . ARG A 1 61 ? 76.248 4.486 114.637 1.00 5.05 ? 141 ARG N CG 1 ATOM 485 C CD . ARG A 1 61 ? 75.816 5.943 114.854 1.00 6.76 ? 141 ARG N CD 1 ATOM 486 N NE . ARG A 1 61 ? 76.425 6.833 113.871 1.00 10.56 ? 141 ARG N NE 1 ATOM 487 C CZ . ARG A 1 61 ? 76.164 6.756 112.535 1.00 10.27 ? 141 ARG N CZ 1 ATOM 488 N NH1 . ARG A 1 61 ? 75.322 5.856 111.965 1.00 10.88 ? 141 ARG N NH1 1 ATOM 489 N NH2 . ARG A 1 61 ? 76.756 7.632 111.712 1.00 7.88 ? 141 ARG N NH2 1 ATOM 490 N N . GLY A 1 62 ? 73.159 1.262 116.084 1.00 2.00 ? 142 GLY N N 1 ATOM 491 C CA . GLY A 1 62 ? 72.722 -0.087 115.805 1.00 2.00 ? 142 GLY N CA 1 ATOM 492 C C . GLY A 1 62 ? 71.534 -0.152 114.869 1.00 4.29 ? 142 GLY N C 1 ATOM 493 O O . GLY A 1 62 ? 70.641 0.682 114.954 1.00 3.74 ? 142 GLY N O 1 ATOM 494 N N . LYS A 1 63 ? 71.381 -1.130 114.010 1.00 6.08 ? 143 LYS N N 1 ATOM 495 C CA . LYS A 1 63 ? 70.291 -1.146 113.065 1.00 8.09 ? 143 LYS N CA 1 ATOM 496 C C . LYS A 1 63 ? 68.898 -1.286 113.651 1.00 8.32 ? 143 LYS N C 1 ATOM 497 O O . LYS A 1 63 ? 67.893 -0.993 113.000 1.00 11.44 ? 143 LYS N O 1 ATOM 498 C CB . LYS A 1 63 ? 70.547 -2.259 112.086 1.00 13.39 ? 143 LYS N CB 1 ATOM 499 C CG . LYS A 1 63 ? 71.820 -2.110 111.292 1.00 17.07 ? 143 LYS N CG 1 ATOM 500 C CD . LYS A 1 63 ? 71.716 -3.118 110.191 1.00 20.31 ? 143 LYS N CD 1 ATOM 501 C CE . LYS A 1 63 ? 73.050 -3.438 109.571 1.00 23.80 ? 143 LYS N CE 1 ATOM 502 N NZ . LYS A 1 63 ? 73.004 -4.792 109.054 1.00 26.83 ? 143 LYS N NZ 1 ATOM 503 N N . HIS A 1 64 ? 68.815 -1.751 114.889 1.00 6.29 ? 144 HIS N N 1 ATOM 504 C CA . HIS A 1 64 ? 67.536 -1.885 115.567 1.00 6.41 ? 144 HIS N CA 1 ATOM 505 C C . HIS A 1 64 ? 67.066 -0.545 116.092 1.00 7.08 ? 144 HIS N C 1 ATOM 506 O O . HIS A 1 64 ? 66.040 -0.471 116.766 1.00 8.15 ? 144 HIS N O 1 ATOM 507 C CB . HIS A 1 64 ? 67.612 -2.846 116.763 1.00 2.11 ? 144 HIS N CB 1 ATOM 508 C CG . HIS A 1 64 ? 67.879 -4.277 116.354 1.00 2.07 ? 144 HIS N CG 1 ATOM 509 N ND1 . HIS A 1 64 ? 67.043 -5.170 115.866 1.00 2.02 ? 144 HIS N ND1 1 ATOM 510 C CD2 . HIS A 1 64 ? 69.123 -4.856 116.350 1.00 2.35 ? 144 HIS N CD2 1 ATOM 511 C CE1 . HIS A 1 64 ? 67.755 -6.228 115.561 1.00 4.19 ? 144 HIS N CE1 1 ATOM 512 N NE2 . HIS A 1 64 ? 69.007 -6.045 115.846 1.00 3.01 ? 144 HIS N NE2 1 ATOM 513 N N . SER A 1 65 ? 67.819 0.523 115.872 1.00 6.41 ? 145 SER N N 1 ATOM 514 C CA . SER A 1 65 ? 67.422 1.841 116.309 1.00 6.09 ? 145 SER N CA 1 ATOM 515 C C . SER A 1 65 ? 66.214 2.332 115.540 1.00 8.08 ? 145 SER N C 1 ATOM 516 O O . SER A 1 65 ? 65.518 3.232 116.000 1.00 11.96 ? 145 SER N O 1 ATOM 517 C CB . SER A 1 65 ? 68.571 2.819 116.104 1.00 6.71 ? 145 SER N CB 1 ATOM 518 O OG . SER A 1 65 ? 68.910 3.104 114.746 1.00 9.36 ? 145 SER N OG 1 ATOM 519 N N . ASN A 1 66 ? 65.993 1.780 114.354 1.00 11.41 ? 146 ASN N N 1 ATOM 520 C CA . ASN A 1 66 ? 64.981 2.229 113.440 1.00 15.22 ? 146 ASN N CA 1 ATOM 521 C C . ASN A 1 66 ? 63.640 1.758 113.852 1.00 14.33 ? 146 ASN N C 1 ATOM 522 O O . ASN A 1 66 ? 63.339 0.571 113.801 1.00 16.04 ? 146 ASN N O 1 ATOM 523 C CB . ASN A 1 66 ? 65.297 1.733 112.026 1.00 20.32 ? 146 ASN N CB 1 ATOM 524 C CG . ASN A 1 66 ? 64.071 1.662 111.135 1.00 29.24 ? 146 ASN N CG 1 ATOM 525 O OD1 . ASN A 1 66 ? 63.235 2.563 111.023 1.00 35.09 ? 146 ASN N OD1 1 ATOM 526 N ND2 . ASN A 1 66 ? 63.989 0.496 110.519 1.00 35.66 ? 146 ASN N ND2 1 ATOM 527 N N . GLY A 1 67 ? 62.910 2.798 114.201 1.00 13.21 ? 147 GLY N N 1 ATOM 528 C CA . GLY A 1 67 ? 61.538 2.648 114.588 1.00 11.81 ? 147 GLY N CA 1 ATOM 529 C C . GLY A 1 67 ? 61.360 2.925 116.050 1.00 12.07 ? 147 GLY N C 1 ATOM 530 O O . GLY A 1 67 ? 60.377 2.475 116.617 1.00 12.38 ? 147 GLY N O 1 ATOM 531 N N . THR A 1 68 ? 62.179 3.732 116.700 1.00 11.06 ? 148 THR N N 1 ATOM 532 C CA . THR A 1 68 ? 62.038 3.938 118.115 1.00 9.91 ? 148 THR N CA 1 ATOM 533 C C . THR A 1 68 ? 61.024 5.012 118.487 1.00 13.05 ? 148 THR N C 1 ATOM 534 O O . THR A 1 68 ? 60.956 5.518 119.612 1.00 14.71 ? 148 THR N O 1 ATOM 535 C CB . THR A 1 68 ? 63.421 4.234 118.616 1.00 8.45 ? 148 THR N CB 1 ATOM 536 O OG1 . THR A 1 68 ? 64.097 5.054 117.673 1.00 7.16 ? 148 THR N OG1 1 ATOM 537 C CG2 . THR A 1 68 ? 64.131 2.932 118.874 1.00 8.90 ? 148 THR N CG2 1 ATOM 538 N N . ILE A 1 69 ? 60.146 5.337 117.531 1.00 12.05 ? 149 ILE N N 1 ATOM 539 C CA . ILE A 1 69 ? 59.119 6.309 117.788 1.00 12.81 ? 149 ILE N CA 1 ATOM 540 C C . ILE A 1 69 ? 58.089 5.708 118.741 1.00 12.55 ? 149 ILE N C 1 ATOM 541 O O . ILE A 1 69 ? 57.464 6.396 119.566 1.00 12.14 ? 149 ILE N O 1 ATOM 542 C CB . ILE A 1 69 ? 58.582 6.704 116.399 1.00 14.18 ? 149 ILE N CB 1 ATOM 543 C CG1 . ILE A 1 69 ? 58.281 8.196 116.511 1.00 13.31 ? 149 ILE N CG1 1 ATOM 544 C CG2 . ILE A 1 69 ? 57.397 5.838 115.936 1.00 14.15 ? 149 ILE N CG2 1 ATOM 545 C CD1 . ILE A 1 69 ? 57.611 8.805 115.273 1.00 13.30 ? 149 ILE N CD1 1 ATOM 546 N N . HIS A 1 70 ? 57.953 4.382 118.640 1.00 12.88 ? 150 HIS N N 1 ATOM 547 C CA . HIS A 1 70 ? 57.033 3.657 119.482 1.00 13.58 ? 150 HIS N CA 1 ATOM 548 C C . HIS A 1 70 ? 57.514 3.628 120.933 1.00 13.29 ? 150 HIS N C 1 ATOM 549 O O . HIS A 1 70 ? 58.600 3.130 121.294 1.00 14.39 ? 150 HIS N O 1 ATOM 550 C CB . HIS A 1 70 ? 56.873 2.226 119.026 1.00 19.30 ? 150 HIS N CB 1 ATOM 551 C CG . HIS A 1 70 ? 56.416 2.159 117.585 1.00 23.66 ? 150 HIS N CG 1 ATOM 552 N ND1 . HIS A 1 70 ? 57.124 1.622 116.582 1.00 25.19 ? 150 HIS N ND1 1 ATOM 553 C CD2 . HIS A 1 70 ? 55.228 2.681 117.098 1.00 26.08 ? 150 HIS N CD2 1 ATOM 554 C CE1 . HIS A 1 70 ? 56.410 1.815 115.497 1.00 26.87 ? 150 HIS N CE1 1 ATOM 555 N NE2 . HIS A 1 70 ? 55.288 2.445 115.819 1.00 27.91 ? 150 HIS N NE2 1 ATOM 556 N N . ASP A 1 71 ? 56.530 4.171 121.683 1.00 11.55 ? 151 ASP N N 1 ATOM 557 C CA . ASP A 1 71 ? 56.600 4.423 123.104 1.00 7.69 ? 151 ASP N CA 1 ATOM 558 C C . ASP A 1 71 ? 56.735 3.183 123.937 1.00 3.89 ? 151 ASP N C 1 ATOM 559 O O . ASP A 1 71 ? 57.411 3.186 124.960 1.00 2.64 ? 151 ASP N O 1 ATOM 560 C CB . ASP A 1 71 ? 55.345 5.158 123.571 1.00 12.21 ? 151 ASP N CB 1 ATOM 561 C CG . ASP A 1 71 ? 55.124 6.562 123.003 1.00 14.82 ? 151 ASP N CG 1 ATOM 562 O OD1 . ASP A 1 71 ? 56.086 7.335 123.076 1.00 17.39 ? 151 ASP N OD1 1 ATOM 563 O OD2 . ASP A 1 71 ? 54.013 6.876 122.528 1.00 15.16 ? 151 ASP N OD2 1 ATOM 564 N N . ARG A 1 72 ? 55.966 2.172 123.527 1.00 4.45 ? 152 ARG N N 1 ATOM 565 C CA . ARG A 1 72 ? 55.975 0.965 124.309 1.00 4.47 ? 152 ARG N CA 1 ATOM 566 C C . ARG A 1 72 ? 56.143 -0.304 123.495 1.00 3.80 ? 152 ARG N C 1 ATOM 567 O O . ARG A 1 72 ? 55.511 -0.566 122.477 1.00 5.32 ? 152 ARG N O 1 ATOM 568 C CB . ARG A 1 72 ? 54.696 0.970 125.142 1.00 6.89 ? 152 ARG N CB 1 ATOM 569 C CG . ARG A 1 72 ? 53.283 0.835 124.591 1.00 11.28 ? 152 ARG N CG 1 ATOM 570 C CD . ARG A 1 72 ? 52.334 1.427 125.633 1.00 10.98 ? 152 ARG N CD 1 ATOM 571 N NE . ARG A 1 72 ? 52.264 2.866 125.445 1.00 14.26 ? 152 ARG N NE 1 ATOM 572 C CZ . ARG A 1 72 ? 51.397 3.393 124.563 1.00 15.47 ? 152 ARG N CZ 1 ATOM 573 N NH1 . ARG A 1 72 ? 50.566 2.640 123.833 1.00 14.34 ? 152 ARG N NH1 1 ATOM 574 N NH2 . ARG A 1 72 ? 51.372 4.708 124.389 1.00 17.69 ? 152 ARG N NH2 1 ATOM 575 N N . SER A 1 73 ? 57.021 -1.137 124.013 1.00 2.79 ? 153 SER N N 1 ATOM 576 C CA . SER A 1 73 ? 57.514 -2.341 123.386 1.00 2.34 ? 153 SER N CA 1 ATOM 577 C C . SER A 1 73 ? 58.116 -3.117 124.507 1.00 2.57 ? 153 SER N C 1 ATOM 578 O O . SER A 1 73 ? 58.416 -2.539 125.563 1.00 3.90 ? 153 SER N O 1 ATOM 579 C CB . SER A 1 73 ? 58.630 -2.024 122.350 1.00 2.50 ? 153 SER N CB 1 ATOM 580 O OG . SER A 1 73 ? 59.908 -1.453 122.727 1.00 5.10 ? 153 SER N OG 1 ATOM 581 N N . GLN A 1 74 ? 58.339 -4.407 124.294 1.00 3.09 ? 154 GLN N N 1 ATOM 582 C CA . GLN A 1 74 ? 59.004 -5.136 125.344 1.00 2.06 ? 154 GLN N CA 1 ATOM 583 C C . GLN A 1 74 ? 60.532 -5.101 125.285 1.00 4.29 ? 154 GLN N C 1 ATOM 584 O O . GLN A 1 74 ? 61.170 -5.965 125.889 1.00 4.40 ? 154 GLN N O 1 ATOM 585 C CB . GLN A 1 74 ? 58.495 -6.602 125.415 1.00 4.32 ? 154 GLN N CB 1 ATOM 586 C CG . GLN A 1 74 ? 58.376 -7.452 124.243 1.00 4.88 ? 154 GLN N CG 1 ATOM 587 C CD . GLN A 1 74 ? 57.118 -7.161 123.467 1.00 4.33 ? 154 GLN N CD 1 ATOM 588 O OE1 . GLN A 1 74 ? 57.003 -6.211 122.707 1.00 8.56 ? 154 GLN N OE1 1 ATOM 589 N NE2 . GLN A 1 74 ? 56.109 -7.973 123.666 1.00 2.22 ? 154 GLN N NE2 1 ATOM 590 N N . TYR A 1 75 ? 61.148 -4.066 124.660 1.00 4.81 ? 155 TYR N N 1 ATOM 591 C CA . TYR A 1 75 ? 62.610 -3.956 124.674 1.00 3.74 ? 155 TYR N CA 1 ATOM 592 C C . TYR A 1 75 ? 63.050 -2.714 125.461 1.00 4.45 ? 155 TYR N C 1 ATOM 593 O O . TYR A 1 75 ? 64.227 -2.463 125.720 1.00 5.80 ? 155 TYR N O 1 ATOM 594 C CB . TYR A 1 75 ? 63.135 -3.965 123.222 1.00 4.08 ? 155 TYR N CB 1 ATOM 595 C CG . TYR A 1 75 ? 62.533 -5.138 122.433 1.00 3.88 ? 155 TYR N CG 1 ATOM 596 C CD1 . TYR A 1 75 ? 62.821 -6.466 122.753 1.00 5.63 ? 155 TYR N CD1 1 ATOM 597 C CD2 . TYR A 1 75 ? 61.590 -4.878 121.467 1.00 2.47 ? 155 TYR N CD2 1 ATOM 598 C CE1 . TYR A 1 75 ? 62.172 -7.517 122.125 1.00 4.41 ? 155 TYR N CE1 1 ATOM 599 C CE2 . TYR A 1 75 ? 60.951 -5.916 120.858 1.00 2.06 ? 155 TYR N CE2 1 ATOM 600 C CZ . TYR A 1 75 ? 61.228 -7.222 121.173 1.00 3.46 ? 155 TYR N CZ 1 ATOM 601 O OH . TYR A 1 75 ? 60.494 -8.215 120.534 1.00 5.46 ? 155 TYR N OH 1 ATOM 602 N N . ARG A 1 76 ? 62.035 -2.011 125.977 1.00 4.77 ? 156 ARG N N 1 ATOM 603 C CA . ARG A 1 76 ? 62.120 -0.865 126.910 1.00 3.50 ? 156 ARG N CA 1 ATOM 604 C C . ARG A 1 76 ? 62.559 -1.315 128.322 1.00 4.80 ? 156 ARG N C 1 ATOM 605 O O . ARG A 1 76 ? 62.116 -2.378 128.792 1.00 5.85 ? 156 ARG N O 1 ATOM 606 C CB . ARG A 1 76 ? 60.734 -0.163 126.999 1.00 5.58 ? 156 ARG N CB 1 ATOM 607 C CG . ARG A 1 76 ? 60.110 0.291 125.700 1.00 4.84 ? 156 ARG N CG 1 ATOM 608 C CD . ARG A 1 76 ? 60.983 1.406 125.198 1.00 3.24 ? 156 ARG N CD 1 ATOM 609 N NE . ARG A 1 76 ? 60.200 2.614 125.088 1.00 2.06 ? 156 ARG N NE 1 ATOM 610 C CZ . ARG A 1 76 ? 60.619 3.812 125.469 1.00 3.69 ? 156 ARG N CZ 1 ATOM 611 N NH1 . ARG A 1 76 ? 61.840 4.081 125.861 1.00 6.99 ? 156 ARG N NH1 1 ATOM 612 N NH2 . ARG A 1 76 ? 59.746 4.782 125.359 1.00 7.25 ? 156 ARG N NH2 1 ATOM 613 N N . ASP A 1 77 ? 63.393 -0.542 129.017 1.00 3.37 ? 157 ASP N N 1 ATOM 614 C CA . ASP A 1 77 ? 64.012 -0.961 130.262 1.00 2.00 ? 157 ASP N CA 1 ATOM 615 C C . ASP A 1 77 ? 64.240 0.352 131.016 1.00 2.01 ? 157 ASP N C 1 ATOM 616 O O . ASP A 1 77 ? 64.705 1.287 130.366 1.00 2.04 ? 157 ASP N O 1 ATOM 617 C CB . ASP A 1 77 ? 65.414 -1.649 130.030 1.00 2.79 ? 157 ASP N CB 1 ATOM 618 C CG . ASP A 1 77 ? 65.820 -2.669 128.818 1.00 2.36 ? 157 ASP N CG 1 ATOM 619 O OD1 . ASP A 1 77 ? 65.520 -3.912 129.022 1.00 2.18 ? 157 ASP N OD1 1 ATOM 620 O OD2 . ASP A 1 77 ? 66.496 -2.248 127.770 1.00 2.33 ? 157 ASP N OD2 1 ATOM 621 N N . LEU A 1 78 ? 63.929 0.615 132.288 1.00 2.00 ? 158 LEU N N 1 ATOM 622 C CA . LEU A 1 78 ? 64.268 1.885 132.922 1.00 2.15 ? 158 LEU N CA 1 ATOM 623 C C . LEU A 1 78 ? 65.713 1.833 133.366 1.00 3.03 ? 158 LEU N C 1 ATOM 624 O O . LEU A 1 78 ? 66.009 0.978 134.187 1.00 4.30 ? 158 LEU N O 1 ATOM 625 C CB . LEU A 1 78 ? 63.422 2.134 134.159 1.00 2.00 ? 158 LEU N CB 1 ATOM 626 C CG . LEU A 1 78 ? 63.936 3.138 135.221 1.00 2.02 ? 158 LEU N CG 1 ATOM 627 C CD1 . LEU A 1 78 ? 63.967 4.542 134.671 1.00 2.19 ? 158 LEU N CD1 1 ATOM 628 C CD2 . LEU A 1 78 ? 63.062 3.004 136.457 1.00 2.00 ? 158 LEU N CD2 1 ATOM 629 N N . ILE A 1 79 ? 66.642 2.664 132.918 1.00 3.20 ? 159 ILE N N 1 ATOM 630 C CA . ILE A 1 79 ? 68.049 2.616 133.284 1.00 2.38 ? 159 ILE N CA 1 ATOM 631 C C . ILE A 1 79 ? 68.508 3.876 133.977 1.00 2.86 ? 159 ILE N C 1 ATOM 632 O O . ILE A 1 79 ? 67.824 4.900 133.992 1.00 2.06 ? 159 ILE N O 1 ATOM 633 C CB . ILE A 1 79 ? 68.953 2.393 132.048 1.00 3.46 ? 159 ILE N CB 1 ATOM 634 C CG1 . ILE A 1 79 ? 68.677 3.394 130.953 1.00 3.98 ? 159 ILE N CG1 1 ATOM 635 C CG2 . ILE A 1 79 ? 68.737 0.997 131.561 1.00 2.00 ? 159 ILE N CG2 1 ATOM 636 C CD1 . ILE A 1 79 ? 69.332 3.250 129.584 1.00 7.11 ? 159 ILE N CD1 1 ATOM 637 N N . SER A 1 80 ? 69.657 3.788 134.622 1.00 4.23 ? 160 SER N N 1 ATOM 638 C CA . SER A 1 80 ? 70.303 4.927 135.249 1.00 4.13 ? 160 SER N CA 1 ATOM 639 C C . SER A 1 80 ? 71.804 4.857 134.965 1.00 2.96 ? 160 SER N C 1 ATOM 640 O O . SER A 1 80 ? 72.324 3.826 134.549 1.00 2.25 ? 160 SER N O 1 ATOM 641 C CB . SER A 1 80 ? 70.051 4.932 136.754 1.00 7.47 ? 160 SER N CB 1 ATOM 642 O OG . SER A 1 80 ? 70.488 3.764 137.404 1.00 10.18 ? 160 SER N OG 1 ATOM 643 N N . TRP A 1 81 ? 72.562 5.922 135.033 1.00 2.40 ? 161 TRP N N 1 ATOM 644 C CA . TRP A 1 81 ? 73.988 5.929 134.778 1.00 2.00 ? 161 TRP N CA 1 ATOM 645 C C . TRP A 1 81 ? 74.435 7.215 135.440 1.00 2.01 ? 161 TRP N C 1 ATOM 646 O O . TRP A 1 81 ? 73.599 8.008 135.887 1.00 2.78 ? 161 TRP N O 1 ATOM 647 C CB . TRP A 1 81 ? 74.255 5.951 133.288 1.00 2.00 ? 161 TRP N CB 1 ATOM 648 C CG . TRP A 1 81 ? 73.618 7.096 132.521 1.00 3.74 ? 161 TRP N CG 1 ATOM 649 C CD1 . TRP A 1 81 ? 74.379 8.172 132.193 1.00 4.18 ? 161 TRP N CD1 1 ATOM 650 C CD2 . TRP A 1 81 ? 72.317 7.216 132.082 1.00 3.64 ? 161 TRP N CD2 1 ATOM 651 N NE1 . TRP A 1 81 ? 73.580 8.973 131.542 1.00 2.00 ? 161 TRP N NE1 1 ATOM 652 C CE2 . TRP A 1 81 ? 72.364 8.442 131.459 1.00 2.01 ? 161 TRP N CE2 1 ATOM 653 C CE3 . TRP A 1 81 ? 71.122 6.523 132.105 1.00 2.36 ? 161 TRP N CE3 1 ATOM 654 C CZ2 . TRP A 1 81 ? 71.265 8.988 130.865 1.00 2.00 ? 161 TRP N CZ2 1 ATOM 655 C CZ3 . TRP A 1 81 ? 70.008 7.068 131.514 1.00 2.36 ? 161 TRP N CZ3 1 ATOM 656 C CH2 . TRP A 1 81 ? 70.085 8.290 130.897 1.00 2.00 ? 161 TRP N CH2 1 ATOM 657 N N . PRO A 1 82 ? 75.720 7.472 135.620 1.00 2.00 ? 162 PRO N N 1 ATOM 658 C CA . PRO A 1 82 ? 76.201 8.699 136.207 1.00 2.00 ? 162 PRO N CA 1 ATOM 659 C C . PRO A 1 82 ? 75.800 10.007 135.553 1.00 2.04 ? 162 PRO N C 1 ATOM 660 O O . PRO A 1 82 ? 75.621 10.122 134.330 1.00 2.06 ? 162 PRO N O 1 ATOM 661 C CB . PRO A 1 82 ? 77.691 8.495 136.269 1.00 2.00 ? 162 PRO N CB 1 ATOM 662 C CG . PRO A 1 82 ? 77.992 7.337 135.369 1.00 2.01 ? 162 PRO N CG 1 ATOM 663 C CD . PRO A 1 82 ? 76.782 6.487 135.617 1.00 2.00 ? 162 PRO N CD 1 ATOM 664 N N . LEU A 1 83 ? 75.681 10.991 136.448 1.00 4.83 ? 163 LEU N N 1 ATOM 665 C CA . LEU A 1 83 ? 75.312 12.346 136.113 1.00 4.29 ? 163 LEU N CA 1 ATOM 666 C C . LEU A 1 83 ? 76.398 12.813 135.153 1.00 6.38 ? 163 LEU N C 1 ATOM 667 O O . LEU A 1 83 ? 77.587 12.576 135.338 1.00 10.40 ? 163 LEU N O 1 ATOM 668 C CB . LEU A 1 83 ? 75.272 13.191 137.402 1.00 2.08 ? 163 LEU N CB 1 ATOM 669 C CG . LEU A 1 83 ? 75.172 14.729 137.453 1.00 2.04 ? 163 LEU N CG 1 ATOM 670 C CD1 . LEU A 1 83 ? 73.750 15.161 137.608 1.00 4.02 ? 163 LEU N CD1 1 ATOM 671 C CD2 . LEU A 1 83 ? 75.899 15.247 138.663 1.00 4.70 ? 163 LEU N CD2 1 ATOM 672 N N . SER A 1 84 ? 75.829 13.285 134.061 1.00 6.14 ? 164 SER N N 1 ATOM 673 C CA . SER A 1 84 ? 76.433 13.843 132.864 1.00 4.76 ? 164 SER N CA 1 ATOM 674 C C . SER A 1 84 ? 77.286 12.983 131.965 1.00 6.07 ? 164 SER N C 1 ATOM 675 O O . SER A 1 84 ? 78.086 13.445 131.143 1.00 9.35 ? 164 SER N O 1 ATOM 676 C CB . SER A 1 84 ? 77.181 15.085 133.253 1.00 2.28 ? 164 SER N CB 1 ATOM 677 O OG . SER A 1 84 ? 76.260 15.899 133.953 1.00 2.00 ? 164 SER N OG 1 ATOM 678 N N . SER A 1 85 ? 77.082 11.691 132.115 1.00 7.52 ? 165 SER N N 1 ATOM 679 C CA . SER A 1 85 ? 77.634 10.781 131.141 1.00 5.76 ? 165 SER N CA 1 ATOM 680 C C . SER A 1 85 ? 76.568 10.408 130.102 1.00 5.07 ? 165 SER N C 1 ATOM 681 O O . SER A 1 85 ? 75.403 10.751 130.315 1.00 2.11 ? 165 SER N O 1 ATOM 682 C CB . SER A 1 85 ? 78.133 9.571 131.880 1.00 5.17 ? 165 SER N CB 1 ATOM 683 O OG . SER A 1 85 ? 79.330 9.945 132.529 1.00 9.18 ? 165 SER N OG 1 ATOM 684 N N . PRO A 1 86 ? 76.827 9.809 128.937 1.00 2.60 ? 166 PRO N N 1 ATOM 685 C CA . PRO A 1 86 ? 75.805 9.230 128.083 1.00 2.00 ? 166 PRO N CA 1 ATOM 686 C C . PRO A 1 86 ? 75.202 7.905 128.594 1.00 2.00 ? 166 PRO N C 1 ATOM 687 O O . PRO A 1 86 ? 75.917 7.200 129.325 1.00 2.69 ? 166 PRO N O 1 ATOM 688 C CB . PRO A 1 86 ? 76.523 9.134 126.733 1.00 2.00 ? 166 PRO N CB 1 ATOM 689 C CG . PRO A 1 86 ? 77.941 8.892 127.111 1.00 2.24 ? 166 PRO N CG 1 ATOM 690 C CD . PRO A 1 86 ? 78.080 9.920 128.218 1.00 2.85 ? 166 PRO N CD 1 ATOM 691 N N . PRO A 1 87 ? 73.957 7.469 128.294 1.00 2.03 ? 167 PRO N N 1 ATOM 692 C CA . PRO A 1 87 ? 73.457 6.140 128.600 1.00 3.20 ? 167 PRO N CA 1 ATOM 693 C C . PRO A 1 87 ? 74.246 5.158 127.762 1.00 4.05 ? 167 PRO N C 1 ATOM 694 O O . PRO A 1 87 ? 73.887 4.953 126.612 1.00 5.78 ? 167 PRO N O 1 ATOM 695 C CB . PRO A 1 87 ? 71.986 6.217 128.276 1.00 2.64 ? 167 PRO N CB 1 ATOM 696 C CG . PRO A 1 87 ? 71.904 7.263 127.214 1.00 2.00 ? 167 PRO N CG 1 ATOM 697 C CD . PRO A 1 87 ? 72.896 8.271 127.712 1.00 2.00 ? 167 PRO N CD 1 ATOM 698 N N . THR A 1 88 ? 75.325 4.621 128.283 1.00 6.31 ? 168 THR N N 1 ATOM 699 C CA . THR A 1 88 ? 76.241 3.786 127.559 1.00 8.85 ? 168 THR N CA 1 ATOM 700 C C . THR A 1 88 ? 75.949 2.336 127.794 1.00 7.38 ? 168 THR N C 1 ATOM 701 O O . THR A 1 88 ? 75.668 2.023 128.942 1.00 7.70 ? 168 THR N O 1 ATOM 702 C CB . THR A 1 88 ? 77.549 4.269 128.047 1.00 13.26 ? 168 THR N CB 1 ATOM 703 O OG1 . THR A 1 88 ? 77.853 5.229 127.076 1.00 19.49 ? 168 THR N OG1 1 ATOM 704 C CG2 . THR A 1 88 ? 78.601 3.248 128.345 1.00 17.92 ? 168 THR N CG2 1 ATOM 705 N N . VAL A 1 89 ? 76.094 1.408 126.869 1.00 5.98 ? 169 VAL N N 1 ATOM 706 C CA . VAL A 1 89 ? 75.726 0.015 127.074 1.00 6.82 ? 169 VAL N CA 1 ATOM 707 C C . VAL A 1 89 ? 76.476 -0.606 128.230 1.00 9.68 ? 169 VAL N C 1 ATOM 708 O O . VAL A 1 89 ? 75.931 -1.456 128.926 1.00 11.18 ? 169 VAL N O 1 ATOM 709 C CB . VAL A 1 89 ? 75.999 -0.782 125.757 1.00 4.73 ? 169 VAL N CB 1 ATOM 710 C CG1 . VAL A 1 89 ? 75.906 -2.262 125.989 1.00 3.88 ? 169 VAL N CG1 1 ATOM 711 C CG2 . VAL A 1 89 ? 74.964 -0.466 124.694 1.00 3.04 ? 169 VAL N CG2 1 ATOM 712 N N . TYR A 1 90 A 77.711 -0.111 128.414 1.00 11.04 ? 169 TYR N N 1 ATOM 713 C CA . TYR A 1 90 A 78.715 -0.585 129.346 1.00 9.99 ? 169 TYR N CA 1 ATOM 714 C C . TYR A 1 90 A 78.685 0.142 130.668 1.00 13.83 ? 169 TYR N C 1 ATOM 715 O O . TYR A 1 90 A 79.614 -0.048 131.446 1.00 17.37 ? 169 TYR N O 1 ATOM 716 C CB . TYR A 1 90 A 80.106 -0.416 128.754 1.00 5.83 ? 169 TYR N CB 1 ATOM 717 C CG . TYR A 1 90 A 80.235 -0.849 127.297 1.00 3.39 ? 169 TYR N CG 1 ATOM 718 C CD1 . TYR A 1 90 A 79.662 -2.011 126.910 1.00 3.01 ? 169 TYR N CD1 1 ATOM 719 C CD2 . TYR A 1 90 A 80.866 -0.054 126.367 1.00 2.12 ? 169 TYR N CD2 1 ATOM 720 C CE1 . TYR A 1 90 A 79.695 -2.367 125.602 1.00 2.86 ? 169 TYR N CE1 1 ATOM 721 C CE2 . TYR A 1 90 A 80.912 -0.409 125.049 1.00 2.00 ? 169 TYR N CE2 1 ATOM 722 C CZ . TYR A 1 90 A 80.313 -1.578 124.697 1.00 2.00 ? 169 TYR N CZ 1 ATOM 723 O OH . TYR A 1 90 A 80.325 -2.014 123.409 1.00 2.76 ? 169 TYR N OH 1 ATOM 724 N N . ASN A 1 91 ? 77.690 0.994 130.977 1.00 17.19 ? 170 ASN N N 1 ATOM 725 C CA . ASN A 1 91 ? 77.631 1.617 132.294 1.00 18.59 ? 170 ASN N CA 1 ATOM 726 C C . ASN A 1 91 ? 76.218 1.983 132.717 1.00 16.55 ? 170 ASN N C 1 ATOM 727 O O . ASN A 1 91 ? 76.036 2.606 133.754 1.00 18.50 ? 170 ASN N O 1 ATOM 728 C CB . ASN A 1 91 ? 78.576 2.847 132.313 1.00 25.17 ? 170 ASN N CB 1 ATOM 729 C CG . ASN A 1 91 ? 78.146 4.126 131.591 1.00 29.96 ? 170 ASN N CG 1 ATOM 730 O OD1 . ASN A 1 91 ? 78.895 5.094 131.521 1.00 34.20 ? 170 ASN N OD1 1 ATOM 731 N ND2 . ASN A 1 91 ? 76.986 4.321 130.974 1.00 29.27 ? 170 ASN N ND2 1 ATOM 732 N N . SER A 1 92 ? 75.153 1.700 131.987 1.00 14.58 ? 171 SER N N 1 ATOM 733 C CA . SER A 1 92 ? 73.818 1.942 132.510 1.00 11.48 ? 171 SER N CA 1 ATOM 734 C C . SER A 1 92 ? 73.472 0.817 133.461 1.00 11.08 ? 171 SER N C 1 ATOM 735 O O . SER A 1 92 ? 73.978 -0.300 133.329 1.00 15.68 ? 171 SER N O 1 ATOM 736 C CB . SER A 1 92 ? 72.796 1.960 131.409 1.00 11.34 ? 171 SER N CB 1 ATOM 737 O OG . SER A 1 92 ? 72.819 3.216 130.745 1.00 14.77 ? 171 SER N OG 1 ATOM 738 N N . ARG A 1 93 ? 72.663 1.147 134.451 1.00 9.72 ? 172 ARG N N 1 ATOM 739 C CA . ARG A 1 93 ? 72.201 0.209 135.426 1.00 11.47 ? 172 ARG N CA 1 ATOM 740 C C . ARG A 1 93 ? 70.729 0.013 135.149 1.00 9.99 ? 172 ARG N C 1 ATOM 741 O O . ARG A 1 93 ? 69.990 0.997 135.166 1.00 11.73 ? 172 ARG N O 1 ATOM 742 C CB . ARG A 1 93 ? 72.417 0.783 136.818 1.00 13.39 ? 172 ARG N CB 1 ATOM 743 C CG . ARG A 1 93 ? 72.519 -0.320 137.864 1.00 17.73 ? 172 ARG N CG 1 ATOM 744 C CD . ARG A 1 93 ? 72.156 0.233 139.235 1.00 21.43 ? 172 ARG N CD 1 ATOM 745 N NE . ARG A 1 93 ? 73.136 1.144 139.800 1.00 23.92 ? 172 ARG N NE 1 ATOM 746 C CZ . ARG A 1 93 ? 72.782 2.236 140.491 1.00 24.61 ? 172 ARG N CZ 1 ATOM 747 N NH1 . ARG A 1 93 ? 71.530 2.736 140.508 1.00 24.20 ? 172 ARG N NH1 1 ATOM 748 N NH2 . ARG A 1 93 ? 73.736 2.964 141.059 1.00 24.41 ? 172 ARG N NH2 1 ATOM 749 N N . VAL A 1 94 ? 70.284 -1.193 134.815 1.00 8.79 ? 173 VAL N N 1 ATOM 750 C CA . VAL A 1 94 ? 68.893 -1.427 134.574 1.00 5.90 ? 173 VAL N CA 1 ATOM 751 C C . VAL A 1 94 ? 68.216 -1.583 135.936 1.00 7.43 ? 173 VAL N C 1 ATOM 752 O O . VAL A 1 94 ? 68.647 -2.362 136.817 1.00 9.12 ? 173 VAL N O 1 ATOM 753 C CB . VAL A 1 94 ? 68.774 -2.648 133.731 1.00 2.96 ? 173 VAL N CB 1 ATOM 754 C CG1 . VAL A 1 94 ? 67.331 -2.871 133.370 1.00 2.09 ? 173 VAL N CG1 1 ATOM 755 C CG2 . VAL A 1 94 ? 69.563 -2.474 132.472 1.00 5.79 ? 173 VAL N CG2 1 ATOM 756 N N . GLU A 1 95 ? 67.185 -0.733 136.077 1.00 6.76 ? 174 GLU N N 1 ATOM 757 C CA . GLU A 1 95 ? 66.356 -0.601 137.261 1.00 5.35 ? 174 GLU N CA 1 ATOM 758 C C . GLU A 1 95 ? 65.110 -1.449 137.417 1.00 6.75 ? 174 GLU N C 1 ATOM 759 O O . GLU A 1 95 ? 64.635 -1.679 138.520 1.00 9.94 ? 174 GLU N O 1 ATOM 760 C CB . GLU A 1 95 ? 65.927 0.800 137.389 1.00 6.83 ? 174 GLU N CB 1 ATOM 761 C CG . GLU A 1 95 ? 67.072 1.772 137.583 1.00 8.26 ? 174 GLU N CG 1 ATOM 762 C CD . GLU A 1 95 ? 67.739 1.770 138.951 1.00 11.31 ? 174 GLU N CD 1 ATOM 763 O OE1 . GLU A 1 95 ? 67.363 1.025 139.869 1.00 15.03 ? 174 GLU N OE1 1 ATOM 764 O OE2 . GLU A 1 95 ? 68.669 2.548 139.087 1.00 15.53 ? 174 GLU N OE2 1 ATOM 765 N N . CYS A 1 96 ? 64.472 -1.848 136.339 1.00 5.57 ? 175 CYS N N 1 ATOM 766 C CA . CYS A 1 96 ? 63.310 -2.730 136.249 1.00 5.02 ? 175 CYS N CA 1 ATOM 767 C C . CYS A 1 96 ? 62.937 -2.725 134.769 1.00 2.77 ? 175 CYS N C 1 ATOM 768 O O . CYS A 1 96 ? 63.621 -2.016 134.006 1.00 2.03 ? 175 CYS N O 1 ATOM 769 C CB . CYS A 1 96 ? 62.079 -2.299 137.046 1.00 6.18 ? 175 CYS N CB 1 ATOM 770 S SG . CYS A 1 96 ? 61.546 -0.593 137.064 1.00 4.49 ? 175 CYS N SG 1 ATOM 771 N N . ILE A 1 97 ? 61.966 -3.535 134.318 1.00 2.78 ? 176 ILE N N 1 ATOM 772 C CA . ILE A 1 97 ? 61.587 -3.658 132.920 1.00 2.42 ? 176 ILE N CA 1 ATOM 773 C C . ILE A 1 97 ? 60.192 -3.109 132.648 1.00 2.01 ? 176 ILE N C 1 ATOM 774 O O . ILE A 1 97 ? 59.283 -3.426 133.399 1.00 2.00 ? 176 ILE N O 1 ATOM 775 C CB . ILE A 1 97 ? 61.696 -5.110 132.547 1.00 2.00 ? 176 ILE N CB 1 ATOM 776 C CG1 . ILE A 1 97 ? 63.099 -5.665 132.923 1.00 2.00 ? 176 ILE N CG1 1 ATOM 777 C CG2 . ILE A 1 97 ? 61.334 -5.251 131.128 1.00 2.00 ? 176 ILE N CG2 1 ATOM 778 C CD1 . ILE A 1 97 ? 64.353 -5.092 132.200 1.00 2.00 ? 176 ILE N CD1 1 ATOM 779 N N . GLY A 1 98 ? 59.948 -2.286 131.637 1.00 2.77 ? 177 GLY N N 1 ATOM 780 C CA . GLY A 1 98 ? 58.642 -1.740 131.332 1.00 2.00 ? 177 GLY N CA 1 ATOM 781 C C . GLY A 1 98 ? 58.826 -0.453 130.535 1.00 2.03 ? 177 GLY N C 1 ATOM 782 O O . GLY A 1 98 ? 59.964 -0.076 130.232 1.00 2.01 ? 177 GLY N O 1 ATOM 783 N N . TRP A 1 99 ? 57.712 0.220 130.221 1.00 2.64 ? 178 TRP N N 1 ATOM 784 C CA . TRP A 1 99 ? 57.635 1.427 129.389 1.00 2.58 ? 178 TRP N CA 1 ATOM 785 C C . TRP A 1 99 ? 57.051 2.723 129.970 1.00 2.70 ? 178 TRP N C 1 ATOM 786 O O . TRP A 1 99 ? 56.644 3.684 129.304 1.00 2.91 ? 178 TRP N O 1 ATOM 787 C CB . TRP A 1 99 ? 56.874 1.039 128.105 1.00 2.00 ? 178 TRP N CB 1 ATOM 788 C CG . TRP A 1 99 ? 55.626 0.163 128.241 1.00 2.10 ? 178 TRP N CG 1 ATOM 789 C CD1 . TRP A 1 99 ? 55.659 -1.123 127.777 1.00 2.07 ? 178 TRP N CD1 1 ATOM 790 C CD2 . TRP A 1 99 ? 54.409 0.483 128.783 1.00 3.05 ? 178 TRP N CD2 1 ATOM 791 N NE1 . TRP A 1 99 ? 54.491 -1.635 128.014 1.00 2.55 ? 178 TRP N NE1 1 ATOM 792 C CE2 . TRP A 1 99 ? 53.722 -0.721 128.614 1.00 3.02 ? 178 TRP N CE2 1 ATOM 793 C CE3 . TRP A 1 99 ? 53.785 1.563 129.405 1.00 2.91 ? 178 TRP N CE3 1 ATOM 794 C CZ2 . TRP A 1 99 ? 52.410 -0.860 129.048 1.00 3.18 ? 178 TRP N CZ2 1 ATOM 795 C CZ3 . TRP A 1 99 ? 52.475 1.424 129.846 1.00 2.00 ? 178 TRP N CZ3 1 ATOM 796 C CH2 . TRP A 1 99 ? 51.803 0.223 129.672 1.00 4.76 ? 178 TRP N CH2 1 ATOM 797 N N . SER A 1 100 ? 56.936 2.704 131.287 1.00 3.92 ? 179 SER N N 1 ATOM 798 C CA . SER A 1 100 ? 56.470 3.827 132.082 1.00 2.03 ? 179 SER N CA 1 ATOM 799 C C . SER A 1 100 ? 57.265 3.713 133.381 1.00 2.00 ? 179 SER N C 1 ATOM 800 O O . SER A 1 100 ? 57.594 2.590 133.749 1.00 2.00 ? 179 SER N O 1 ATOM 801 C CB . SER A 1 100 ? 55.016 3.639 132.327 1.00 2.65 ? 179 SER N CB 1 ATOM 802 O OG . SER A 1 100 ? 54.531 4.890 132.702 1.00 2.03 ? 179 SER N OG 1 ATOM 803 N N . SER A 1 101 ? 57.632 4.719 134.136 1.00 2.00 ? 180 SER N N 1 ATOM 804 C CA . SER A 1 101 ? 58.342 4.484 135.375 1.00 3.13 ? 180 SER N CA 1 ATOM 805 C C . SER A 1 101 ? 58.460 5.742 136.196 1.00 4.04 ? 180 SER N C 1 ATOM 806 O O . SER A 1 101 ? 58.283 6.880 135.720 1.00 4.08 ? 180 SER N O 1 ATOM 807 C CB . SER A 1 101 ? 59.788 3.967 135.152 1.00 2.01 ? 180 SER N CB 1 ATOM 808 O OG . SER A 1 101 ? 60.775 4.941 134.782 1.00 3.91 ? 180 SER N OG 1 ATOM 809 N N . THR A 1 102 ? 58.697 5.489 137.457 1.00 3.30 ? 181 THR N N 1 ATOM 810 C CA . THR A 1 102 ? 59.010 6.519 138.387 1.00 2.00 ? 181 THR N CA 1 ATOM 811 C C . THR A 1 102 ? 60.086 5.857 139.257 1.00 2.88 ? 181 THR N C 1 ATOM 812 O O . THR A 1 102 ? 60.241 4.626 139.252 1.00 2.49 ? 181 THR N O 1 ATOM 813 C CB . THR A 1 102 ? 57.687 6.840 139.083 1.00 2.00 ? 181 THR N CB 1 ATOM 814 O OG1 . THR A 1 102 ? 57.790 8.211 139.375 1.00 2.83 ? 181 THR N OG1 1 ATOM 815 C CG2 . THR A 1 102 ? 57.401 6.098 140.376 1.00 2.05 ? 181 THR N CG2 1 ATOM 816 N N . SER A 1 103 ? 60.901 6.618 139.992 1.00 3.88 ? 182 SER N N 1 ATOM 817 C CA . SER A 1 103 ? 61.868 6.085 140.900 1.00 4.19 ? 182 SER N CA 1 ATOM 818 C C . SER A 1 103 ? 62.186 7.167 141.907 1.00 3.90 ? 182 SER N C 1 ATOM 819 O O . SER A 1 103 ? 62.119 8.321 141.507 1.00 2.00 ? 182 SER N O 1 ATOM 820 C CB . SER A 1 103 ? 63.079 5.709 140.127 1.00 4.37 ? 182 SER N CB 1 ATOM 821 O OG . SER A 1 103 ? 64.006 5.067 140.989 1.00 3.79 ? 182 SER N OG 1 ATOM 822 N N . CYS A 1 104 ? 62.520 6.880 143.167 1.00 3.80 ? 183 CYS N N 1 ATOM 823 C CA . CYS A 1 104 ? 62.855 7.869 144.159 1.00 2.03 ? 183 CYS N CA 1 ATOM 824 C C . CYS A 1 104 ? 63.363 7.249 145.418 1.00 2.00 ? 183 CYS N C 1 ATOM 825 O O . CYS A 1 104 ? 63.048 6.113 145.727 1.00 2.00 ? 183 CYS N O 1 ATOM 826 C CB . CYS A 1 104 ? 61.679 8.682 144.524 1.00 4.11 ? 183 CYS N CB 1 ATOM 827 S SG . CYS A 1 104 ? 60.145 7.897 145.057 1.00 4.28 ? 183 CYS N SG 1 ATOM 828 N N . HIS A 1 105 ? 64.233 7.910 146.144 1.00 2.00 ? 184 HIS N N 1 ATOM 829 C CA . HIS A 1 105 ? 64.849 7.350 147.308 1.00 3.04 ? 184 HIS N CA 1 ATOM 830 C C . HIS A 1 105 ? 64.123 7.855 148.500 1.00 3.36 ? 184 HIS N C 1 ATOM 831 O O . HIS A 1 105 ? 63.961 9.067 148.672 1.00 2.65 ? 184 HIS N O 1 ATOM 832 C CB . HIS A 1 105 ? 66.275 7.790 147.378 1.00 2.00 ? 184 HIS N CB 1 ATOM 833 C CG . HIS A 1 105 ? 67.250 6.945 148.180 1.00 2.00 ? 184 HIS N CG 1 ATOM 834 N ND1 . HIS A 1 105 ? 67.306 6.673 149.464 1.00 2.16 ? 184 HIS N ND1 1 ATOM 835 C CD2 . HIS A 1 105 ? 68.320 6.322 147.604 1.00 2.12 ? 184 HIS N CD2 1 ATOM 836 C CE1 . HIS A 1 105 ? 68.353 5.918 149.666 1.00 2.00 ? 184 HIS N CE1 1 ATOM 837 N NE2 . HIS A 1 105 ? 68.970 5.704 148.538 1.00 2.00 ? 184 HIS N NE2 1 ATOM 838 N N . ASP A 1 106 ? 63.750 6.950 149.393 1.00 4.69 ? 185 ASP N N 1 ATOM 839 C CA . ASP A 1 106 ? 63.084 7.387 150.588 1.00 8.70 ? 185 ASP N CA 1 ATOM 840 C C . ASP A 1 106 ? 63.988 7.839 151.732 1.00 10.47 ? 185 ASP N C 1 ATOM 841 O O . ASP A 1 106 ? 63.510 8.275 152.788 1.00 11.66 ? 185 ASP N O 1 ATOM 842 C CB . ASP A 1 106 ? 62.144 6.280 151.058 1.00 8.85 ? 185 ASP N CB 1 ATOM 843 C CG . ASP A 1 106 ? 62.619 4.929 151.594 1.00 9.97 ? 185 ASP N CG 1 ATOM 844 O OD1 . ASP A 1 106 ? 63.765 4.785 152.031 1.00 8.80 ? 185 ASP N OD1 1 ATOM 845 O OD2 . ASP A 1 106 ? 61.759 4.030 151.602 1.00 8.68 ? 185 ASP N OD2 1 ATOM 846 N N . GLY A 1 107 ? 65.304 7.857 151.522 1.00 12.31 ? 186 GLY N N 1 ATOM 847 C CA . GLY A 1 107 ? 66.263 8.161 152.577 1.00 13.79 ? 186 GLY N CA 1 ATOM 848 C C . GLY A 1 107 ? 67.117 6.933 152.916 1.00 16.39 ? 186 GLY N C 1 ATOM 849 O O . GLY A 1 107 ? 68.322 7.059 153.172 1.00 18.42 ? 186 GLY N O 1 ATOM 850 N N . ARG A 1 108 ? 66.510 5.745 152.833 1.00 16.95 ? 187 ARG N N 1 ATOM 851 C CA . ARG A 1 108 ? 67.154 4.500 153.183 1.00 16.77 ? 187 ARG N CA 1 ATOM 852 C C . ARG A 1 108 ? 67.529 3.710 151.947 1.00 15.23 ? 187 ARG N C 1 ATOM 853 O O . ARG A 1 108 ? 68.718 3.560 151.647 1.00 17.66 ? 187 ARG N O 1 ATOM 854 C CB . ARG A 1 108 ? 66.193 3.781 154.059 1.00 21.86 ? 187 ARG N CB 1 ATOM 855 C CG . ARG A 1 108 ? 66.301 4.402 155.426 1.00 25.56 ? 187 ARG N CG 1 ATOM 856 C CD . ARG A 1 108 ? 65.173 3.931 156.292 1.00 30.70 ? 187 ARG N CD 1 ATOM 857 N NE . ARG A 1 108 ? 65.136 2.488 156.262 1.00 2.47 ? 187 ARG N NE 1 ATOM 858 C CZ . ARG A 1 108 ? 65.351 1.768 157.372 1.00 2.38 ? 187 ARG N CZ 1 ATOM 859 N NH1 . ARG A 1 108 ? 65.499 2.405 158.577 1.00 2.23 ? 187 ARG N NH1 1 ATOM 860 N NH2 . ARG A 1 108 ? 65.416 0.406 157.287 1.00 2.16 ? 187 ARG N NH2 1 ATOM 861 N N . ALA A 1 109 ? 66.522 3.239 151.203 1.00 12.04 ? 188 ALA N N 1 ATOM 862 C CA . ALA A 1 109 ? 66.732 2.598 149.919 1.00 7.90 ? 188 ALA N CA 1 ATOM 863 C C . ALA A 1 109 ? 65.876 3.359 148.940 1.00 7.14 ? 188 ALA N C 1 ATOM 864 O O . ALA A 1 109 ? 65.247 4.353 149.333 1.00 10.05 ? 188 ALA N O 1 ATOM 865 C CB . ALA A 1 109 ? 66.257 1.167 149.954 1.00 6.40 ? 188 ALA N CB 1 ATOM 866 N N . ARG A 1 110 ? 65.871 2.925 147.673 1.00 5.03 ? 189 ARG N N 1 ATOM 867 C CA . ARG A 1 110 ? 64.983 3.559 146.731 1.00 4.12 ? 189 ARG N CA 1 ATOM 868 C C . ARG A 1 110 ? 63.997 2.588 146.111 1.00 3.90 ? 189 ARG N C 1 ATOM 869 O O . ARG A 1 110 ? 64.185 1.360 146.030 1.00 2.89 ? 189 ARG N O 1 ATOM 870 C CB . ARG A 1 110 ? 65.738 4.234 145.626 1.00 5.10 ? 189 ARG N CB 1 ATOM 871 C CG . ARG A 1 110 ? 66.056 3.487 144.370 1.00 6.63 ? 189 ARG N CG 1 ATOM 872 C CD . ARG A 1 110 ? 65.918 4.466 143.244 1.00 3.58 ? 189 ARG N CD 1 ATOM 873 N NE . ARG A 1 110 ? 66.878 5.535 143.389 1.00 5.90 ? 189 ARG N NE 1 ATOM 874 C CZ . ARG A 1 110 ? 66.559 6.787 143.087 1.00 7.71 ? 189 ARG N CZ 1 ATOM 875 N NH1 . ARG A 1 110 ? 65.355 7.109 142.603 1.00 9.96 ? 189 ARG N NH1 1 ATOM 876 N NH2 . ARG A 1 110 ? 67.497 7.721 143.226 1.00 6.65 ? 189 ARG N NH2 1 ATOM 877 N N . MET A 1 111 ? 62.935 3.238 145.678 1.00 4.32 ? 190 MET N N 1 ATOM 878 C CA . MET A 1 111 ? 61.830 2.573 145.058 1.00 5.31 ? 190 MET N CA 1 ATOM 879 C C . MET A 1 111 ? 61.972 2.970 143.602 1.00 5.91 ? 190 MET N C 1 ATOM 880 O O . MET A 1 111 ? 62.377 4.088 143.270 1.00 9.75 ? 190 MET N O 1 ATOM 881 C CB . MET A 1 111 ? 60.546 3.105 145.657 1.00 2.07 ? 190 MET N CB 1 ATOM 882 C CG . MET A 1 111 ? 59.347 2.392 145.031 1.00 2.04 ? 190 MET N CG 1 ATOM 883 S SD . MET A 1 111 ? 57.763 2.984 145.618 1.00 5.74 ? 190 MET N SD 1 ATOM 884 C CE . MET A 1 111 ? 57.720 4.561 144.814 1.00 2.08 ? 190 MET N CE 1 ATOM 885 N N . SER A 1 112 ? 61.733 1.990 142.752 1.00 5.06 ? 191 SER N N 1 ATOM 886 C CA . SER A 1 112 ? 61.624 2.163 141.331 1.00 4.26 ? 191 SER N CA 1 ATOM 887 C C . SER A 1 112 ? 60.334 1.447 141.007 1.00 4.88 ? 191 SER N C 1 ATOM 888 O O . SER A 1 112 ? 59.994 0.450 141.643 1.00 3.59 ? 191 SER N O 1 ATOM 889 C CB . SER A 1 112 ? 62.786 1.519 140.612 1.00 4.72 ? 191 SER N CB 1 ATOM 890 O OG . SER A 1 112 ? 63.953 2.310 140.753 1.00 4.06 ? 191 SER N OG 1 ATOM 891 N N . ILE A 1 113 ? 59.595 1.984 140.034 1.00 4.37 ? 192 ILE N N 1 ATOM 892 C CA . ILE A 1 113 ? 58.321 1.447 139.607 1.00 3.39 ? 192 ILE N CA 1 ATOM 893 C C . ILE A 1 113 ? 58.300 1.373 138.071 1.00 2.46 ? 192 ILE N C 1 ATOM 894 O O . ILE A 1 113 ? 58.260 2.411 137.409 1.00 2.03 ? 192 ILE N O 1 ATOM 895 C CB . ILE A 1 113 ? 57.170 2.365 140.179 1.00 5.26 ? 192 ILE N CB 1 ATOM 896 C CG1 . ILE A 1 113 ? 57.251 2.556 141.694 1.00 2.03 ? 192 ILE N CG1 1 ATOM 897 C CG2 . ILE A 1 113 ? 55.856 1.724 139.766 1.00 4.22 ? 192 ILE N CG2 1 ATOM 898 C CD1 . ILE A 1 113 ? 55.958 3.050 142.339 1.00 5.37 ? 192 ILE N CD1 1 ATOM 899 N N . CYS A 1 114 ? 58.369 0.172 137.481 1.00 4.38 ? 193 CYS N N 1 ATOM 900 C CA . CYS A 1 114 ? 58.196 0.033 136.031 1.00 6.10 ? 193 CYS N CA 1 ATOM 901 C C . CYS A 1 114 ? 56.919 -0.679 135.548 1.00 7.19 ? 193 CYS N C 1 ATOM 902 O O . CYS A 1 114 ? 56.712 -1.864 135.833 1.00 12.83 ? 193 CYS N O 1 ATOM 903 C CB . CYS A 1 114 ? 59.291 -0.752 135.368 1.00 5.64 ? 193 CYS N CB 1 ATOM 904 S SG . CYS A 1 114 ? 60.916 -0.058 135.259 1.00 7.72 ? 193 CYS N SG 1 ATOM 905 N N . ILE A 1 115 ? 56.024 -0.018 134.811 1.00 5.98 ? 194 ILE N N 1 ATOM 906 C CA . ILE A 1 115 ? 54.827 -0.627 134.222 1.00 5.27 ? 194 ILE N CA 1 ATOM 907 C C . ILE A 1 115 ? 55.155 -1.272 132.864 1.00 5.99 ? 194 ILE N C 1 ATOM 908 O O . ILE A 1 115 ? 55.901 -0.753 132.029 1.00 7.00 ? 194 ILE N O 1 ATOM 909 C CB . ILE A 1 115 ? 53.749 0.455 134.079 1.00 4.67 ? 194 ILE N CB 1 ATOM 910 C CG1 . ILE A 1 115 ? 53.465 1.033 135.430 1.00 2.00 ? 194 ILE N CG1 1 ATOM 911 C CG2 . ILE A 1 115 ? 52.479 -0.142 133.493 1.00 5.53 ? 194 ILE N CG2 1 ATOM 912 C CD1 . ILE A 1 115 ? 52.719 2.357 135.381 1.00 2.00 ? 194 ILE N CD1 1 ATOM 913 N N . SER A 1 116 ? 54.625 -2.455 132.634 1.00 6.33 ? 195 SER N N 1 ATOM 914 C CA . SER A 1 116 ? 54.933 -3.208 131.452 1.00 7.70 ? 195 SER N CA 1 ATOM 915 C C . SER A 1 116 ? 53.627 -3.696 130.899 1.00 10.34 ? 195 SER N C 1 ATOM 916 O O . SER A 1 116 ? 52.648 -3.701 131.664 1.00 12.30 ? 195 SER N O 1 ATOM 917 C CB . SER A 1 116 ? 55.733 -4.368 131.848 1.00 7.49 ? 195 SER N CB 1 ATOM 918 O OG . SER A 1 116 ? 56.228 -4.977 130.685 1.00 8.92 ? 195 SER N OG 1 ATOM 919 N N . GLY A 1 117 ? 53.580 -4.088 129.620 1.00 10.63 ? 196 GLY N N 1 ATOM 920 C CA . GLY A 1 117 ? 52.359 -4.697 129.134 1.00 8.64 ? 196 GLY N CA 1 ATOM 921 C C . GLY A 1 117 ? 51.800 -4.354 127.760 1.00 9.02 ? 196 GLY N C 1 ATOM 922 O O . GLY A 1 117 ? 52.063 -3.300 127.151 1.00 10.21 ? 196 GLY N O 1 ATOM 923 N N . PRO A 1 118 ? 50.960 -5.299 127.286 1.00 9.04 ? 197 PRO N N 1 ATOM 924 C CA . PRO A 1 118 ? 49.832 -5.078 126.400 1.00 8.66 ? 197 PRO N CA 1 ATOM 925 C C . PRO A 1 118 ? 49.067 -3.908 126.934 1.00 10.52 ? 197 PRO N C 1 ATOM 926 O O . PRO A 1 118 ? 48.889 -3.759 128.144 1.00 12.67 ? 197 PRO N O 1 ATOM 927 C CB . PRO A 1 118 ? 48.945 -6.273 126.462 1.00 9.34 ? 197 PRO N CB 1 ATOM 928 C CG . PRO A 1 118 ? 49.859 -7.355 126.877 1.00 11.35 ? 197 PRO N CG 1 ATOM 929 C CD . PRO A 1 118 ? 50.751 -6.620 127.882 1.00 10.76 ? 197 PRO N CD 1 ATOM 930 N N . ASN A 1 119 ? 48.465 -3.164 126.030 1.00 11.01 ? 198 ASN N N 1 ATOM 931 C CA . ASN A 1 119 ? 47.730 -1.988 126.416 1.00 12.28 ? 198 ASN N CA 1 ATOM 932 C C . ASN A 1 119 ? 46.457 -2.301 127.160 1.00 13.08 ? 198 ASN N C 1 ATOM 933 O O . ASN A 1 119 ? 45.932 -1.404 127.811 1.00 15.90 ? 198 ASN N O 1 ATOM 934 C CB . ASN A 1 119 ? 47.446 -1.186 125.182 1.00 14.47 ? 198 ASN N CB 1 ATOM 935 C CG . ASN A 1 119 ? 48.696 -0.578 124.536 1.00 15.75 ? 198 ASN N CG 1 ATOM 936 O OD1 . ASN A 1 119 ? 48.510 0.319 123.735 1.00 12.34 ? 198 ASN N OD1 1 ATOM 937 N ND2 . ASN A 1 119 ? 49.995 -0.885 124.692 1.00 20.60 ? 198 ASN N ND2 1 ATOM 938 N N . ASN A 1 120 ? 45.995 -3.537 127.227 1.00 13.37 ? 199 ASN N N 1 ATOM 939 C CA . ASN A 1 120 ? 44.807 -3.850 127.977 1.00 14.96 ? 199 ASN N CA 1 ATOM 940 C C . ASN A 1 120 ? 45.020 -4.855 129.095 1.00 15.79 ? 199 ASN N C 1 ATOM 941 O O . ASN A 1 120 ? 44.089 -5.464 129.635 1.00 19.14 ? 199 ASN N O 1 ATOM 942 C CB . ASN A 1 120 ? 43.787 -4.367 127.027 1.00 16.80 ? 199 ASN N CB 1 ATOM 943 C CG . ASN A 1 120 ? 44.154 -5.714 126.470 1.00 18.77 ? 199 ASN N CG 1 ATOM 944 O OD1 . ASN A 1 120 ? 45.313 -6.079 126.312 1.00 20.11 ? 199 ASN N OD1 1 ATOM 945 N ND2 . ASN A 1 120 ? 43.150 -6.480 126.122 1.00 20.21 ? 199 ASN N ND2 1 ATOM 946 N N . ASN A 1 121 ? 46.259 -5.082 129.469 1.00 15.17 ? 200 ASN N N 1 ATOM 947 C CA . ASN A 1 121 ? 46.526 -6.055 130.487 1.00 11.56 ? 200 ASN N CA 1 ATOM 948 C C . ASN A 1 121 ? 47.834 -5.593 131.086 1.00 12.07 ? 200 ASN N C 1 ATOM 949 O O . ASN A 1 121 ? 48.734 -6.412 131.258 1.00 10.78 ? 200 ASN N O 1 ATOM 950 C CB . ASN A 1 121 ? 46.661 -7.415 129.830 1.00 10.67 ? 200 ASN N CB 1 ATOM 951 C CG . ASN A 1 121 ? 45.776 -8.436 130.501 1.00 10.66 ? 200 ASN N CG 1 ATOM 952 O OD1 . ASN A 1 121 ? 45.396 -8.247 131.658 1.00 14.26 ? 200 ASN N OD1 1 ATOM 953 N ND2 . ASN A 1 121 ? 45.425 -9.563 129.857 1.00 10.62 ? 200 ASN N ND2 1 ATOM 954 N N . ALA A 1 122 ? 47.980 -4.297 131.401 1.00 12.42 ? 201 ALA N N 1 ATOM 955 C CA . ALA A 1 122 ? 49.247 -3.785 131.870 1.00 14.39 ? 201 ALA N CA 1 ATOM 956 C C . ALA A 1 122 ? 49.415 -4.057 133.373 1.00 14.95 ? 201 ALA N C 1 ATOM 957 O O . ALA A 1 122 ? 48.401 -4.273 134.026 1.00 15.36 ? 201 ALA N O 1 ATOM 958 C CB . ALA A 1 122 ? 49.268 -2.310 131.541 1.00 14.68 ? 201 ALA N CB 1 ATOM 959 N N . SER A 1 123 ? 50.628 -4.085 133.936 1.00 14.31 ? 202 SER N N 1 ATOM 960 C CA . SER A 1 123 ? 50.975 -4.413 135.325 1.00 12.58 ? 202 SER N CA 1 ATOM 961 C C . SER A 1 123 ? 52.181 -3.655 135.883 1.00 12.74 ? 202 SER N C 1 ATOM 962 O O . SER A 1 123 ? 53.241 -3.652 135.256 1.00 13.84 ? 202 SER N O 1 ATOM 963 C CB . SER A 1 123 ? 51.317 -5.893 135.491 1.00 11.40 ? 202 SER N CB 1 ATOM 964 O OG . SER A 1 123 ? 50.179 -6.709 135.266 1.00 13.14 ? 202 SER N OG 1 ATOM 965 N N . ALA A 1 124 ? 52.104 -3.009 137.024 1.00 11.65 ? 203 ALA N N 1 ATOM 966 C CA . ALA A 1 124 ? 53.209 -2.287 137.587 1.00 10.79 ? 203 ALA N CA 1 ATOM 967 C C . ALA A 1 124 ? 53.972 -3.152 138.577 1.00 10.88 ? 203 ALA N C 1 ATOM 968 O O . ALA A 1 124 ? 53.256 -3.855 139.285 1.00 10.37 ? 203 ALA N O 1 ATOM 969 C CB . ALA A 1 124 ? 52.669 -1.083 138.320 1.00 10.40 ? 203 ALA N CB 1 ATOM 970 N N . VAL A 1 125 ? 55.303 -3.243 138.724 1.00 10.56 ? 204 VAL N N 1 ATOM 971 C CA . VAL A 1 125 ? 55.882 -3.944 139.868 1.00 10.80 ? 204 VAL N CA 1 ATOM 972 C C . VAL A 1 125 ? 56.799 -2.893 140.482 1.00 10.39 ? 204 VAL N C 1 ATOM 973 O O . VAL A 1 125 ? 57.473 -2.108 139.802 1.00 9.46 ? 204 VAL N O 1 ATOM 974 C CB . VAL A 1 125 ? 56.616 -5.340 139.453 1.00 12.95 ? 204 VAL N CB 1 ATOM 975 C CG1 . VAL A 1 125 ? 57.256 -5.289 138.117 1.00 17.46 ? 204 VAL N CG1 1 ATOM 976 C CG2 . VAL A 1 125 ? 57.718 -5.695 140.427 1.00 15.05 ? 204 VAL N CG2 1 ATOM 977 N N . ILE A 1 126 ? 56.508 -2.764 141.782 1.00 10.22 ? 205 ILE N N 1 ATOM 978 C CA . ILE A 1 126 ? 57.085 -1.772 142.680 1.00 5.55 ? 205 ILE N CA 1 ATOM 979 C C . ILE A 1 126 ? 58.323 -2.377 143.317 1.00 5.03 ? 205 ILE N C 1 ATOM 980 O O . ILE A 1 126 ? 58.242 -3.180 144.251 1.00 5.22 ? 205 ILE N O 1 ATOM 981 C CB . ILE A 1 126 ? 56.033 -1.335 143.786 1.00 2.57 ? 205 ILE N CB 1 ATOM 982 C CG1 . ILE A 1 126 ? 54.896 -0.563 143.166 1.00 2.03 ? 205 ILE N CG1 1 ATOM 983 C CG2 . ILE A 1 126 ? 56.646 -0.392 144.812 1.00 2.11 ? 205 ILE N CG2 1 ATOM 984 C CD1 . ILE A 1 126 ? 53.902 -1.346 142.282 1.00 3.33 ? 205 ILE N CD1 1 ATOM 985 N N . TRP A 1 127 ? 59.482 -2.098 142.737 1.00 4.14 ? 206 TRP N N 1 ATOM 986 C CA . TRP A 1 127 ? 60.748 -2.568 143.276 1.00 2.96 ? 206 TRP N CA 1 ATOM 987 C C . TRP A 1 127 ? 61.192 -1.684 144.452 1.00 4.48 ? 206 TRP N C 1 ATOM 988 O O . TRP A 1 127 ? 61.075 -0.442 144.429 1.00 5.26 ? 206 TRP N O 1 ATOM 989 C CB . TRP A 1 127 ? 61.810 -2.552 142.162 1.00 2.02 ? 206 TRP N CB 1 ATOM 990 C CG . TRP A 1 127 ? 61.617 -3.516 140.996 1.00 2.98 ? 206 TRP N CG 1 ATOM 991 C CD1 . TRP A 1 127 ? 60.538 -3.467 140.133 1.00 3.20 ? 206 TRP N CD1 1 ATOM 992 C CD2 . TRP A 1 127 ? 62.511 -4.507 140.669 1.00 2.99 ? 206 TRP N CD2 1 ATOM 993 N NE1 . TRP A 1 127 ? 60.761 -4.430 139.265 1.00 2.69 ? 206 TRP N NE1 1 ATOM 994 C CE2 . TRP A 1 127 ? 61.915 -5.070 139.549 1.00 2.00 ? 206 TRP N CE2 1 ATOM 995 C CE3 . TRP A 1 127 ? 63.712 -5.010 141.128 1.00 3.07 ? 206 TRP N CE3 1 ATOM 996 C CZ2 . TRP A 1 127 ? 62.503 -6.139 138.890 1.00 2.03 ? 206 TRP N CZ2 1 ATOM 997 C CZ3 . TRP A 1 127 ? 64.311 -6.073 140.479 1.00 2.00 ? 206 TRP N CZ3 1 ATOM 998 C CH2 . TRP A 1 127 ? 63.707 -6.634 139.366 1.00 2.02 ? 206 TRP N CH2 1 ATOM 999 N N . TYR A 1 128 ? 61.671 -2.320 145.539 1.00 6.68 ? 207 TYR N N 1 ATOM 1000 C CA . TYR A 1 128 ? 62.216 -1.568 146.666 1.00 6.55 ? 207 TYR N CA 1 ATOM 1001 C C . TYR A 1 128 ? 63.476 -2.270 147.120 1.00 6.35 ? 207 TYR N C 1 ATOM 1002 O O . TYR A 1 128 ? 63.498 -3.451 147.453 1.00 7.44 ? 207 TYR N O 1 ATOM 1003 C CB . TYR A 1 128 ? 61.314 -1.496 147.877 1.00 6.73 ? 207 TYR N CB 1 ATOM 1004 C CG . TYR A 1 128 ? 61.932 -0.620 148.975 1.00 8.43 ? 207 TYR N CG 1 ATOM 1005 C CD1 . TYR A 1 128 ? 62.201 0.735 148.738 1.00 8.57 ? 207 TYR N CD1 1 ATOM 1006 C CD2 . TYR A 1 128 ? 62.172 -1.148 150.232 1.00 10.39 ? 207 TYR N CD2 1 ATOM 1007 C CE1 . TYR A 1 128 ? 62.692 1.534 149.755 1.00 10.46 ? 207 TYR N CE1 1 ATOM 1008 C CE2 . TYR A 1 128 ? 62.659 -0.337 151.230 1.00 11.46 ? 207 TYR N CE2 1 ATOM 1009 C CZ . TYR A 1 128 ? 62.904 0.983 150.996 1.00 9.98 ? 207 TYR N CZ 1 ATOM 1010 O OH . TYR A 1 128 ? 63.327 1.775 152.031 1.00 9.41 ? 207 TYR N OH 1 ATOM 1011 N N . ASN A 1 129 ? 64.545 -1.467 147.102 1.00 6.93 ? 208 ASN N N 1 ATOM 1012 C CA . ASN A 1 129 ? 65.907 -1.891 147.403 1.00 7.33 ? 208 ASN N CA 1 ATOM 1013 C C . ASN A 1 129 ? 66.423 -2.994 146.468 1.00 9.50 ? 208 ASN N C 1 ATOM 1014 O O . ASN A 1 129 ? 66.888 -4.097 146.790 1.00 9.38 ? 208 ASN N O 1 ATOM 1015 C CB . ASN A 1 129 ? 66.022 -2.386 148.828 1.00 7.90 ? 208 ASN N CB 1 ATOM 1016 C CG . ASN A 1 129 ? 67.484 -2.413 149.145 1.00 9.34 ? 208 ASN N CG 1 ATOM 1017 O OD1 . ASN A 1 129 ? 68.127 -1.401 148.919 1.00 9.48 ? 208 ASN N OD1 1 ATOM 1018 N ND2 . ASN A 1 129 ? 68.041 -3.508 149.601 1.00 10.77 ? 208 ASN N ND2 1 ATOM 1019 N N . ARG A 1 130 ? 66.259 -2.618 145.201 1.00 12.74 ? 209 ARG N N 1 ATOM 1020 C CA . ARG A 1 130 ? 66.540 -3.475 144.061 1.00 13.80 ? 209 ARG N CA 1 ATOM 1021 C C . ARG A 1 130 ? 65.882 -4.868 144.162 1.00 10.55 ? 209 ARG N C 1 ATOM 1022 O O . ARG A 1 130 ? 66.329 -5.838 143.558 1.00 11.48 ? 209 ARG N O 1 ATOM 1023 C CB . ARG A 1 130 ? 68.100 -3.556 143.856 1.00 20.19 ? 209 ARG N CB 1 ATOM 1024 C CG . ARG A 1 130 ? 68.751 -2.160 143.674 1.00 28.16 ? 209 ARG N CG 1 ATOM 1025 C CD . ARG A 1 130 ? 70.102 -1.987 142.924 1.00 33.11 ? 209 ARG N CD 1 ATOM 1026 N NE . ARG A 1 130 ? 69.887 -1.861 141.486 1.00 39.57 ? 209 ARG N NE 1 ATOM 1027 C CZ . ARG A 1 130 ? 70.365 -2.767 140.608 1.00 44.36 ? 209 ARG N CZ 1 ATOM 1028 N NH1 . ARG A 1 130 ? 71.269 -3.700 140.947 1.00 47.01 ? 209 ARG N NH1 1 ATOM 1029 N NH2 . ARG A 1 130 ? 70.022 -2.682 139.319 1.00 47.69 ? 209 ARG N NH2 1 ATOM 1030 N N . ARG A 1 131 ? 64.783 -5.050 144.882 1.00 8.28 ? 210 ARG N N 1 ATOM 1031 C CA . ARG A 1 131 ? 64.080 -6.300 144.816 1.00 5.34 ? 210 ARG N CA 1 ATOM 1032 C C . ARG A 1 131 ? 62.616 -6.038 144.553 1.00 4.18 ? 210 ARG N C 1 ATOM 1033 O O . ARG A 1 131 ? 62.052 -5.025 144.996 1.00 6.07 ? 210 ARG N O 1 ATOM 1034 C CB . ARG A 1 131 ? 64.202 -7.043 146.107 1.00 6.95 ? 210 ARG N CB 1 ATOM 1035 C CG . ARG A 1 131 ? 65.495 -7.768 146.299 1.00 4.17 ? 210 ARG N CG 1 ATOM 1036 C CD . ARG A 1 131 ? 65.824 -7.896 147.790 1.00 4.75 ? 210 ARG N CD 1 ATOM 1037 N NE . ARG A 1 131 ? 66.961 -8.779 147.810 1.00 5.45 ? 210 ARG N NE 1 ATOM 1038 C CZ . ARG A 1 131 ? 67.912 -8.859 148.734 1.00 6.56 ? 210 ARG N CZ 1 ATOM 1039 N NH1 . ARG A 1 131 ? 67.986 -7.989 149.748 1.00 3.08 ? 210 ARG N NH1 1 ATOM 1040 N NH2 . ARG A 1 131 ? 68.848 -9.824 148.528 1.00 10.54 ? 210 ARG N NH2 1 ATOM 1041 N N . PRO A 1 132 ? 61.962 -6.899 143.775 1.00 3.21 ? 211 PRO N N 1 ATOM 1042 C CA . PRO A 1 132 ? 60.556 -6.742 143.441 1.00 4.31 ? 211 PRO N CA 1 ATOM 1043 C C . PRO A 1 132 ? 59.723 -7.029 144.691 1.00 6.01 ? 211 PRO N C 1 ATOM 1044 O O . PRO A 1 132 ? 59.807 -8.102 145.321 1.00 9.21 ? 211 PRO N O 1 ATOM 1045 C CB . PRO A 1 132 ? 60.373 -7.704 142.281 1.00 2.73 ? 211 PRO N CB 1 ATOM 1046 C CG . PRO A 1 132 ? 61.323 -8.809 142.650 1.00 2.02 ? 211 PRO N CG 1 ATOM 1047 C CD . PRO A 1 132 ? 62.547 -8.064 143.133 1.00 2.06 ? 211 PRO N CD 1 ATOM 1048 N N . VAL A 1 133 ? 58.958 -6.020 145.092 1.00 7.42 ? 212 VAL N N 1 ATOM 1049 C CA . VAL A 1 133 ? 58.222 -6.143 146.333 1.00 7.46 ? 212 VAL N CA 1 ATOM 1050 C C . VAL A 1 133 ? 56.719 -6.264 146.135 1.00 8.91 ? 212 VAL N C 1 ATOM 1051 O O . VAL A 1 133 ? 56.083 -7.164 146.697 1.00 9.03 ? 212 VAL N O 1 ATOM 1052 C CB . VAL A 1 133 ? 58.630 -4.937 147.181 1.00 6.64 ? 212 VAL N CB 1 ATOM 1053 C CG1 . VAL A 1 133 ? 57.799 -4.792 148.412 1.00 9.46 ? 212 VAL N CG1 1 ATOM 1054 C CG2 . VAL A 1 133 ? 60.081 -5.141 147.537 1.00 5.35 ? 212 VAL N CG2 1 ATOM 1055 N N . THR A 1 134 ? 56.116 -5.417 145.327 1.00 9.99 ? 213 THR N N 1 ATOM 1056 C CA . THR A 1 134 ? 54.657 -5.423 145.170 1.00 12.06 ? 213 THR N CA 1 ATOM 1057 C C . THR A 1 134 ? 54.359 -5.340 143.682 1.00 11.75 ? 213 THR N C 1 ATOM 1058 O O . THR A 1 134 ? 55.249 -4.990 142.895 1.00 10.29 ? 213 THR N O 1 ATOM 1059 C CB . THR A 1 134 ? 54.082 -4.204 145.934 1.00 13.94 ? 213 THR N CB 1 ATOM 1060 O OG1 . THR A 1 134 ? 54.680 -4.319 147.215 1.00 18.60 ? 213 THR N OG1 1 ATOM 1061 C CG2 . THR A 1 134 ? 52.556 -4.102 146.026 1.00 13.18 ? 213 THR N CG2 1 ATOM 1062 N N . GLU A 1 135 ? 53.123 -5.601 143.267 1.00 10.88 ? 214 GLU N N 1 ATOM 1063 C CA . GLU A 1 135 ? 52.734 -5.528 141.856 1.00 11.55 ? 214 GLU N CA 1 ATOM 1064 C C . GLU A 1 135 ? 51.251 -5.119 141.838 1.00 10.43 ? 214 GLU N C 1 ATOM 1065 O O . GLU A 1 135 ? 50.501 -5.493 142.748 1.00 10.33 ? 214 GLU N O 1 ATOM 1066 C CB . GLU A 1 135 ? 53.014 -6.906 141.161 1.00 11.61 ? 214 GLU N CB 1 ATOM 1067 C CG . GLU A 1 135 ? 53.005 -8.188 142.005 1.00 12.24 ? 214 GLU N CG 1 ATOM 1068 C CD . GLU A 1 135 ? 54.249 -8.610 142.803 1.00 13.23 ? 214 GLU N CD 1 ATOM 1069 O OE1 . GLU A 1 135 ? 55.335 -8.456 142.276 1.00 12.68 ? 214 GLU N OE1 1 ATOM 1070 O OE2 . GLU A 1 135 ? 54.144 -9.126 143.924 1.00 16.97 ? 214 GLU N OE2 1 ATOM 1071 N N . ILE A 1 136 ? 50.831 -4.226 140.949 1.00 8.44 ? 215 ILE N N 1 ATOM 1072 C CA . ILE A 1 136 ? 49.456 -3.725 140.869 1.00 6.33 ? 215 ILE N CA 1 ATOM 1073 C C . ILE A 1 136 ? 49.156 -3.947 139.413 1.00 6.96 ? 215 ILE N C 1 ATOM 1074 O O . ILE A 1 136 ? 50.031 -3.826 138.565 1.00 7.57 ? 215 ILE N O 1 ATOM 1075 C CB . ILE A 1 136 ? 49.352 -2.221 141.177 1.00 4.81 ? 215 ILE N CB 1 ATOM 1076 C CG1 . ILE A 1 136 ? 49.792 -2.019 142.568 1.00 4.53 ? 215 ILE N CG1 1 ATOM 1077 C CG2 . ILE A 1 136 ? 47.934 -1.685 141.018 1.00 2.01 ? 215 ILE N CG2 1 ATOM 1078 C CD1 . ILE A 1 136 ? 50.359 -0.623 142.643 1.00 3.10 ? 215 ILE N CD1 1 ATOM 1079 N N . ASN A 1 137 ? 47.937 -4.312 139.127 1.00 5.72 ? 216 ASN N N 1 ATOM 1080 C CA . ASN A 1 137 ? 47.526 -4.638 137.779 1.00 6.00 ? 216 ASN N CA 1 ATOM 1081 C C . ASN A 1 137 ? 46.539 -3.609 137.196 1.00 5.41 ? 216 ASN N C 1 ATOM 1082 O O . ASN A 1 137 ? 46.053 -2.743 137.923 1.00 6.35 ? 216 ASN N O 1 ATOM 1083 C CB . ASN A 1 137 ? 46.995 -6.042 137.920 1.00 5.33 ? 216 ASN N CB 1 ATOM 1084 C CG . ASN A 1 137 ? 46.529 -6.733 136.667 1.00 5.88 ? 216 ASN N CG 1 ATOM 1085 O OD1 . ASN A 1 137 ? 45.366 -7.105 136.647 1.00 6.30 ? 216 ASN N OD1 1 ATOM 1086 N ND2 . ASN A 1 137 ? 47.303 -6.980 135.610 1.00 4.85 ? 216 ASN N ND2 1 ATOM 1087 N N . THR A 1 138 ? 46.180 -3.631 135.914 1.00 5.17 ? 217 THR N N 1 ATOM 1088 C CA . THR A 1 138 ? 45.411 -2.567 135.297 1.00 4.89 ? 217 THR N CA 1 ATOM 1089 C C . THR A 1 138 ? 43.993 -2.481 135.841 1.00 6.52 ? 217 THR N C 1 ATOM 1090 O O . THR A 1 138 ? 43.266 -3.457 135.798 1.00 4.71 ? 217 THR N O 1 ATOM 1091 C CB . THR A 1 138 ? 45.538 -2.877 133.771 1.00 5.11 ? 217 THR N CB 1 ATOM 1092 O OG1 . THR A 1 138 ? 44.832 -1.841 133.147 1.00 4.84 ? 217 THR N OG1 1 ATOM 1093 C CG2 . THR A 1 138 ? 45.034 -4.226 133.312 1.00 2.99 ? 217 THR N CG2 1 ATOM 1094 N N . TRP A 1 139 ? 43.525 -1.362 136.378 1.00 7.10 ? 218 TRP N N 1 ATOM 1095 C CA . TRP A 1 139 ? 42.127 -1.248 136.824 1.00 6.07 ? 218 TRP N CA 1 ATOM 1096 C C . TRP A 1 139 ? 41.120 -0.848 135.741 1.00 4.71 ? 218 TRP N C 1 ATOM 1097 O O . TRP A 1 139 ? 39.921 -1.107 135.774 1.00 6.30 ? 218 TRP N O 1 ATOM 1098 C CB . TRP A 1 139 ? 42.030 -0.249 137.989 1.00 5.15 ? 218 TRP N CB 1 ATOM 1099 C CG . TRP A 1 139 ? 42.784 1.062 137.849 1.00 5.16 ? 218 TRP N CG 1 ATOM 1100 C CD1 . TRP A 1 139 ? 42.216 2.155 137.279 1.00 5.99 ? 218 TRP N CD1 1 ATOM 1101 C CD2 . TRP A 1 139 ? 44.060 1.286 138.274 1.00 3.99 ? 218 TRP N CD2 1 ATOM 1102 N NE1 . TRP A 1 139 ? 43.126 3.078 137.339 1.00 5.73 ? 218 TRP N NE1 1 ATOM 1103 C CE2 . TRP A 1 139 ? 44.234 2.612 137.910 1.00 4.05 ? 218 TRP N CE2 1 ATOM 1104 C CE3 . TRP A 1 139 ? 45.089 0.595 138.883 1.00 5.42 ? 218 TRP N CE3 1 ATOM 1105 C CZ2 . TRP A 1 139 ? 45.406 3.300 138.158 1.00 3.79 ? 218 TRP N CZ2 1 ATOM 1106 C CZ3 . TRP A 1 139 ? 46.271 1.263 139.137 1.00 4.25 ? 218 TRP N CZ3 1 ATOM 1107 C CH2 . TRP A 1 139 ? 46.425 2.598 138.771 1.00 3.70 ? 218 TRP N CH2 1 ATOM 1108 N N . ALA A 1 140 ? 41.624 -0.140 134.756 1.00 5.52 ? 219 ALA N N 1 ATOM 1109 C CA . ALA A 1 140 ? 40.763 0.251 133.690 1.00 8.99 ? 219 ALA N CA 1 ATOM 1110 C C . ALA A 1 140 ? 41.174 -0.371 132.379 1.00 10.55 ? 219 ALA N C 1 ATOM 1111 O O . ALA A 1 140 ? 40.659 0.017 131.344 1.00 12.09 ? 219 ALA N O 1 ATOM 1112 C CB . ALA A 1 140 ? 40.780 1.766 133.561 1.00 7.87 ? 219 ALA N CB 1 ATOM 1113 N N . ARG A 1 141 ? 42.122 -1.286 132.313 1.00 13.21 ? 220 ARG N N 1 ATOM 1114 C CA . ARG A 1 141 ? 42.549 -1.895 131.055 1.00 15.62 ? 220 ARG N CA 1 ATOM 1115 C C . ARG A 1 141 ? 42.833 -1.025 129.824 1.00 15.52 ? 220 ARG N C 1 ATOM 1116 O O . ARG A 1 141 ? 42.727 -1.519 128.710 1.00 13.94 ? 220 ARG N O 1 ATOM 1117 C CB . ARG A 1 141 ? 41.539 -2.999 130.678 1.00 18.56 ? 220 ARG N CB 1 ATOM 1118 C CG . ARG A 1 141 ? 41.731 -4.189 131.577 1.00 21.84 ? 220 ARG N CG 1 ATOM 1119 C CD . ARG A 1 141 ? 40.797 -5.396 131.445 1.00 24.89 ? 220 ARG N CD 1 ATOM 1120 N NE . ARG A 1 141 ? 41.149 -6.202 132.613 1.00 29.42 ? 220 ARG N NE 1 ATOM 1121 C CZ . ARG A 1 141 ? 42.042 -7.216 132.588 1.00 32.52 ? 220 ARG N CZ 1 ATOM 1122 N NH1 . ARG A 1 141 ? 42.553 -7.633 131.415 1.00 33.31 ? 220 ARG N NH1 1 ATOM 1123 N NH2 . ARG A 1 141 ? 42.389 -7.847 133.735 1.00 33.65 ? 220 ARG N NH2 1 ATOM 1124 N N . ASN A 1 142 ? 43.190 0.248 129.908 1.00 15.54 ? 221 ASN N N 1 ATOM 1125 C CA . ASN A 1 142 ? 43.653 0.935 128.728 1.00 15.44 ? 221 ASN N CA 1 ATOM 1126 C C . ASN A 1 142 ? 44.815 1.820 129.129 1.00 13.47 ? 221 ASN N C 1 ATOM 1127 O O . ASN A 1 142 ? 44.690 2.931 129.625 1.00 15.26 ? 221 ASN N O 1 ATOM 1128 C CB . ASN A 1 142 ? 42.555 1.777 128.103 1.00 19.82 ? 221 ASN N CB 1 ATOM 1129 C CG . ASN A 1 142 ? 43.164 2.449 126.882 1.00 21.45 ? 221 ASN N CG 1 ATOM 1130 O OD1 . ASN A 1 142 ? 43.510 1.814 125.886 1.00 22.83 ? 221 ASN N OD1 1 ATOM 1131 N ND2 . ASN A 1 142 ? 43.540 3.714 126.898 1.00 20.64 ? 221 ASN N ND2 1 ATOM 1132 N N . ILE A 1 143 ? 45.966 1.218 128.902 1.00 9.74 ? 222 ILE N N 1 ATOM 1133 C CA . ILE A 1 143 ? 47.292 1.732 129.219 1.00 7.13 ? 222 ILE N CA 1 ATOM 1134 C C . ILE A 1 143 ? 47.510 2.366 130.605 1.00 7.76 ? 222 ILE N C 1 ATOM 1135 O O . ILE A 1 143 ? 47.196 3.526 130.850 1.00 8.88 ? 222 ILE N O 1 ATOM 1136 C CB . ILE A 1 143 ? 47.726 2.755 128.142 1.00 5.85 ? 222 ILE N CB 1 ATOM 1137 C CG1 . ILE A 1 143 ? 47.507 2.312 126.723 1.00 6.04 ? 222 ILE N CG1 1 ATOM 1138 C CG2 . ILE A 1 143 ? 49.234 2.869 128.272 1.00 2.93 ? 222 ILE N CG2 1 ATOM 1139 C CD1 . ILE A 1 143 ? 47.054 3.535 125.928 1.00 2.12 ? 222 ILE N CD1 1 ATOM 1140 N N . LEU A 1 144 ? 48.136 1.611 131.500 1.00 6.78 ? 223 LEU N N 1 ATOM 1141 C CA . LEU A 1 144 ? 48.318 2.003 132.880 1.00 4.42 ? 223 LEU N CA 1 ATOM 1142 C C . LEU A 1 144 ? 49.589 2.776 132.787 1.00 5.48 ? 223 LEU N C 1 ATOM 1143 O O . LEU A 1 144 ? 50.526 2.238 132.222 1.00 7.05 ? 223 LEU N O 1 ATOM 1144 C CB . LEU A 1 144 ? 48.481 0.761 133.706 1.00 3.36 ? 223 LEU N CB 1 ATOM 1145 C CG . LEU A 1 144 ? 49.120 0.815 135.089 1.00 2.91 ? 223 LEU N CG 1 ATOM 1146 C CD1 . LEU A 1 144 ? 48.293 1.729 136.000 1.00 2.03 ? 223 LEU N CD1 1 ATOM 1147 C CD2 . LEU A 1 144 ? 49.268 -0.598 135.628 1.00 2.02 ? 223 LEU N CD2 1 ATOM 1148 N N . ARG A 1 145 ? 49.647 3.998 133.267 1.00 5.13 ? 224 ARG N N 1 ATOM 1149 C CA . ARG A 1 145 ? 50.871 4.758 133.160 1.00 3.38 ? 224 ARG N CA 1 ATOM 1150 C C . ARG A 1 145 ? 51.252 5.509 134.422 1.00 2.73 ? 224 ARG N C 1 ATOM 1151 O O . ARG A 1 145 ? 50.393 5.689 135.274 1.00 2.00 ? 224 ARG N O 1 ATOM 1152 C CB . ARG A 1 145 ? 50.746 5.750 132.053 1.00 3.32 ? 224 ARG N CB 1 ATOM 1153 C CG . ARG A 1 145 ? 49.537 5.739 131.158 1.00 3.80 ? 224 ARG N CG 1 ATOM 1154 C CD . ARG A 1 145 ? 48.622 6.951 131.319 1.00 3.06 ? 224 ARG N CD 1 ATOM 1155 N NE . ARG A 1 145 ? 47.786 6.987 130.124 1.00 5.83 ? 224 ARG N NE 1 ATOM 1156 C CZ . ARG A 1 145 ? 46.446 6.920 130.065 1.00 8.17 ? 224 ARG N CZ 1 ATOM 1157 N NH1 . ARG A 1 145 ? 45.632 6.939 131.104 1.00 8.80 ? 224 ARG N NH1 1 ATOM 1158 N NH2 . ARG A 1 145 ? 45.885 6.907 128.877 1.00 8.29 ? 224 ARG N NH2 1 ATOM 1159 N N . THR A 1 146 ? 52.488 5.947 134.634 1.00 2.37 ? 225 THR N N 1 ATOM 1160 C CA . THR A 1 146 ? 52.809 6.736 135.782 1.00 2.55 ? 225 THR N CA 1 ATOM 1161 C C . THR A 1 146 ? 53.768 7.858 135.422 1.00 3.06 ? 225 THR N C 1 ATOM 1162 O O . THR A 1 146 ? 54.230 7.962 134.297 1.00 3.82 ? 225 THR N O 1 ATOM 1163 C CB . THR A 1 146 ? 53.423 5.840 136.793 1.00 4.95 ? 225 THR N CB 1 ATOM 1164 O OG1 . THR A 1 146 ? 53.391 6.622 137.981 1.00 6.45 ? 225 THR N OG1 1 ATOM 1165 C CG2 . THR A 1 146 ? 54.806 5.328 136.428 1.00 6.64 ? 225 THR N CG2 1 ATOM 1166 N N . GLN A 1 147 ? 54.146 8.668 136.402 1.00 4.89 ? 226 GLN N N 1 ATOM 1167 C CA . GLN A 1 147 ? 54.961 9.870 136.280 1.00 4.24 ? 226 GLN N CA 1 ATOM 1168 C C . GLN A 1 147 ? 56.012 10.211 135.224 1.00 3.85 ? 226 GLN N C 1 ATOM 1169 O O . GLN A 1 147 ? 55.898 11.266 134.621 1.00 5.70 ? 226 GLN N O 1 ATOM 1170 C CB . GLN A 1 147 ? 55.626 10.086 137.667 1.00 4.23 ? 226 GLN N CB 1 ATOM 1171 C CG . GLN A 1 147 ? 54.604 10.694 138.597 1.00 3.04 ? 226 GLN N CG 1 ATOM 1172 C CD . GLN A 1 147 ? 55.024 10.855 140.048 1.00 2.00 ? 226 GLN N CD 1 ATOM 1173 O OE1 . GLN A 1 147 ? 56.199 11.052 140.320 1.00 3.68 ? 226 GLN N OE1 1 ATOM 1174 N NE2 . GLN A 1 147 ? 54.146 10.808 141.057 1.00 2.00 ? 226 GLN N NE2 1 ATOM 1175 N N . GLU A 1 148 ? 57.037 9.420 134.989 1.00 3.85 ? 227 GLU N N 1 ATOM 1176 C CA . GLU A 1 148 ? 58.202 9.756 134.160 1.00 3.54 ? 227 GLU N CA 1 ATOM 1177 C C . GLU A 1 148 ? 59.034 10.937 134.717 1.00 5.05 ? 227 GLU N C 1 ATOM 1178 O O . GLU A 1 148 ? 59.725 11.639 133.973 1.00 3.48 ? 227 GLU N O 1 ATOM 1179 C CB . GLU A 1 148 ? 57.816 10.092 132.709 1.00 2.03 ? 227 GLU N CB 1 ATOM 1180 C CG . GLU A 1 148 ? 56.662 9.301 132.110 1.00 2.04 ? 227 GLU N CG 1 ATOM 1181 C CD . GLU A 1 148 ? 56.740 7.782 132.063 1.00 4.45 ? 227 GLU N CD 1 ATOM 1182 O OE1 . GLU A 1 148 ? 57.803 7.255 132.318 1.00 5.13 ? 227 GLU N OE1 1 ATOM 1183 O OE2 . GLU A 1 148 ? 55.734 7.126 131.756 1.00 5.15 ? 227 GLU N OE2 1 ATOM 1184 N N . SER A 1 149 ? 58.974 11.070 136.051 1.00 5.50 ? 228 SER N N 1 ATOM 1185 C CA . SER A 1 149 ? 59.764 11.933 136.921 1.00 6.29 ? 228 SER N CA 1 ATOM 1186 C C . SER A 1 149 ? 60.000 11.120 138.195 1.00 7.93 ? 228 SER N C 1 ATOM 1187 O O . SER A 1 149 ? 59.629 9.938 138.240 1.00 5.65 ? 228 SER N O 1 ATOM 1188 C CB . SER A 1 149 ? 59.029 13.145 137.397 1.00 7.94 ? 228 SER N CB 1 ATOM 1189 O OG . SER A 1 149 ? 58.821 13.987 136.306 1.00 10.60 ? 228 SER N OG 1 ATOM 1190 N N . GLU A 1 150 ? 60.576 11.721 139.248 1.00 10.16 ? 229 GLU N N 1 ATOM 1191 C CA . GLU A 1 150 ? 60.829 11.039 140.492 1.00 12.29 ? 229 GLU N CA 1 ATOM 1192 C C . GLU A 1 150 ? 59.704 11.421 141.409 1.00 14.36 ? 229 GLU N C 1 ATOM 1193 O O . GLU A 1 150 ? 59.153 12.520 141.306 1.00 17.11 ? 229 GLU N O 1 ATOM 1194 C CB . GLU A 1 150 ? 62.140 11.477 141.155 1.00 13.44 ? 229 GLU N CB 1 ATOM 1195 C CG . GLU A 1 150 ? 62.282 12.976 141.420 1.00 15.57 ? 229 GLU N CG 1 ATOM 1196 C CD . GLU A 1 150 ? 63.230 13.396 142.512 1.00 17.29 ? 229 GLU N CD 1 ATOM 1197 O OE1 . GLU A 1 150 ? 64.156 12.677 142.855 1.00 17.65 ? 229 GLU N OE1 1 ATOM 1198 O OE2 . GLU A 1 150 ? 63.043 14.464 143.050 1.00 19.18 ? 229 GLU N OE2 1 ATOM 1199 N N . CYS A 1 151 ? 59.466 10.545 142.361 1.00 12.85 ? 230 CYS N N 1 ATOM 1200 C CA . CYS A 1 151 ? 58.407 10.703 143.333 1.00 9.58 ? 230 CYS N CA 1 ATOM 1201 C C . CYS A 1 151 ? 59.076 11.302 144.527 1.00 9.75 ? 230 CYS N C 1 ATOM 1202 O O . CYS A 1 151 ? 60.299 11.330 144.598 1.00 9.12 ? 230 CYS N O 1 ATOM 1203 C CB . CYS A 1 151 ? 57.814 9.343 143.712 1.00 8.05 ? 230 CYS N CB 1 ATOM 1204 S SG . CYS A 1 151 ? 58.887 7.881 143.498 1.00 5.09 ? 230 CYS N SG 1 ATOM 1205 N N . VAL A 1 152 ? 58.352 11.855 145.475 1.00 11.82 ? 231 VAL N N 1 ATOM 1206 C CA . VAL A 1 152 ? 58.976 12.380 146.680 1.00 9.20 ? 231 VAL N CA 1 ATOM 1207 C C . VAL A 1 152 ? 58.533 11.565 147.890 1.00 8.02 ? 231 VAL N C 1 ATOM 1208 O O . VAL A 1 152 ? 57.381 11.145 148.030 1.00 6.93 ? 231 VAL N O 1 ATOM 1209 C CB . VAL A 1 152 ? 58.597 13.890 146.795 1.00 11.37 ? 231 VAL N CB 1 ATOM 1210 C CG1 . VAL A 1 152 ? 59.177 14.581 148.030 1.00 11.64 ? 231 VAL N CG1 1 ATOM 1211 C CG2 . VAL A 1 152 ? 59.175 14.580 145.552 1.00 10.76 ? 231 VAL N CG2 1 ATOM 1212 N N . CYS A 1 153 ? 59.465 11.332 148.776 1.00 5.77 ? 232 CYS N N 1 ATOM 1213 C CA . CYS A 1 153 ? 59.166 10.559 149.964 1.00 6.48 ? 232 CYS N CA 1 ATOM 1214 C C . CYS A 1 153 ? 59.159 11.457 151.181 1.00 6.63 ? 232 CYS N C 1 ATOM 1215 O O . CYS A 1 153 ? 59.792 12.503 151.148 1.00 8.78 ? 232 CYS N O 1 ATOM 1216 C CB . CYS A 1 153 ? 60.208 9.443 150.094 1.00 6.04 ? 232 CYS N CB 1 ATOM 1217 S SG . CYS A 1 153 ? 60.143 8.194 148.732 1.00 3.19 ? 232 CYS N SG 1 ATOM 1218 N N . GLN A 1 154 ? 58.433 11.095 152.234 1.00 5.99 ? 233 GLN N N 1 ATOM 1219 C CA . GLN A 1 154 ? 58.337 11.799 153.512 1.00 6.44 ? 233 GLN N CA 1 ATOM 1220 C C . GLN A 1 154 ? 57.989 10.777 154.574 1.00 7.51 ? 233 GLN N C 1 ATOM 1221 O O . GLN A 1 154 ? 56.965 10.089 154.548 1.00 6.62 ? 233 GLN N O 1 ATOM 1222 C CB . GLN A 1 154 ? 57.250 12.859 153.501 1.00 7.08 ? 233 GLN N CB 1 ATOM 1223 C CG . GLN A 1 154 ? 56.578 13.269 154.818 1.00 6.83 ? 233 GLN N CG 1 ATOM 1224 C CD . GLN A 1 154 ? 57.275 14.334 155.609 1.00 2.05 ? 233 GLN N CD 1 ATOM 1225 O OE1 . GLN A 1 154 ? 58.252 14.938 155.191 1.00 2.06 ? 233 GLN N OE1 1 ATOM 1226 N NE2 . GLN A 1 154 ? 56.793 14.646 156.784 1.00 2.00 ? 233 GLN N NE2 1 ATOM 1227 N N . ASN A 1 155 ? 58.915 10.634 155.486 1.00 10.32 ? 234 ASN N N 1 ATOM 1228 C CA . ASN A 1 155 ? 58.794 9.724 156.610 1.00 14.31 ? 234 ASN N CA 1 ATOM 1229 C C . ASN A 1 155 ? 58.535 8.273 156.222 1.00 14.38 ? 234 ASN N C 1 ATOM 1230 O O . ASN A 1 155 ? 58.027 7.442 156.963 1.00 22.09 ? 234 ASN N O 1 ATOM 1231 C CB . ASN A 1 155 ? 57.698 10.308 157.504 1.00 15.65 ? 234 ASN N CB 1 ATOM 1232 C CG . ASN A 1 155 ? 57.444 9.540 158.764 1.00 18.37 ? 234 ASN N CG 1 ATOM 1233 O OD1 . ASN A 1 155 ? 58.350 9.402 159.581 1.00 19.84 ? 234 ASN N OD1 1 ATOM 1234 N ND2 . ASN A 1 155 ? 56.213 9.086 158.980 1.00 24.24 ? 234 ASN N ND2 1 ATOM 1235 N N . GLY A 1 156 ? 58.959 7.935 155.012 1.00 12.12 ? 235 GLY N N 1 ATOM 1236 C CA . GLY A 1 156 ? 58.789 6.581 154.496 1.00 9.14 ? 235 GLY N CA 1 ATOM 1237 C C . GLY A 1 156 ? 57.677 6.469 153.466 1.00 8.39 ? 235 GLY N C 1 ATOM 1238 O O . GLY A 1 156 ? 57.709 5.568 152.618 1.00 11.89 ? 235 GLY N O 1 ATOM 1239 N N . VAL A 1 157 ? 56.724 7.416 153.543 1.00 5.66 ? 236 VAL N N 1 ATOM 1240 C CA . VAL A 1 157 ? 55.565 7.494 152.670 1.00 5.04 ? 236 VAL N CA 1 ATOM 1241 C C . VAL A 1 157 ? 55.982 8.225 151.411 1.00 5.44 ? 236 VAL N C 1 ATOM 1242 O O . VAL A 1 157 ? 56.476 9.347 151.492 1.00 8.75 ? 236 VAL N O 1 ATOM 1243 C CB . VAL A 1 157 ? 54.449 8.240 153.442 1.00 4.37 ? 236 VAL N CB 1 ATOM 1244 C CG1 . VAL A 1 157 ? 53.235 8.585 152.577 1.00 3.78 ? 236 VAL N CG1 1 ATOM 1245 C CG2 . VAL A 1 157 ? 53.989 7.319 154.518 1.00 3.12 ? 236 VAL N CG2 1 ATOM 1246 N N . CYS A 1 158 ? 55.857 7.599 150.259 1.00 3.68 ? 237 CYS N N 1 ATOM 1247 C CA . CYS A 1 158 ? 56.148 8.256 148.986 1.00 4.79 ? 237 CYS N CA 1 ATOM 1248 C C . CYS A 1 158 ? 54.879 8.225 148.143 1.00 5.84 ? 237 CYS N C 1 ATOM 1249 O O . CYS A 1 158 ? 54.479 7.147 147.699 1.00 7.42 ? 237 CYS N O 1 ATOM 1250 C CB . CYS A 1 158 ? 57.256 7.521 148.262 1.00 3.90 ? 237 CYS N CB 1 ATOM 1251 S SG . CYS A 1 158 ? 58.617 7.120 149.375 1.00 3.49 ? 237 CYS N SG 1 ATOM 1252 N N . PRO A 1 159 ? 54.095 9.286 147.988 1.00 4.35 ? 238 PRO N N 1 ATOM 1253 C CA . PRO A 1 159 ? 52.953 9.283 147.067 1.00 3.94 ? 238 PRO N CA 1 ATOM 1254 C C . PRO A 1 159 ? 53.435 9.190 145.630 1.00 5.92 ? 238 PRO N C 1 ATOM 1255 O O . PRO A 1 159 ? 54.502 9.758 145.329 1.00 7.31 ? 238 PRO N O 1 ATOM 1256 C CB . PRO A 1 159 ? 52.206 10.568 147.382 1.00 2.97 ? 238 PRO N CB 1 ATOM 1257 C CG . PRO A 1 159 ? 53.284 11.453 147.954 1.00 3.65 ? 238 PRO N CG 1 ATOM 1258 C CD . PRO A 1 159 ? 54.107 10.476 148.833 1.00 2.31 ? 238 PRO N CD 1 ATOM 1259 N N . VAL A 1 160 ? 52.636 8.485 144.797 1.00 5.59 ? 239 VAL N N 1 ATOM 1260 C CA . VAL A 1 160 ? 52.877 8.189 143.388 1.00 4.66 ? 239 VAL N CA 1 ATOM 1261 C C . VAL A 1 160 ? 51.531 8.297 142.633 1.00 5.06 ? 239 VAL N C 1 ATOM 1262 O O . VAL A 1 160 ? 50.480 7.777 142.991 1.00 7.13 ? 239 VAL N O 1 ATOM 1263 C CB . VAL A 1 160 ? 53.521 6.727 143.227 1.00 3.41 ? 239 VAL N CB 1 ATOM 1264 C CG1 . VAL A 1 160 ? 53.761 6.396 141.760 1.00 2.90 ? 239 VAL N CG1 1 ATOM 1265 C CG2 . VAL A 1 160 ? 54.915 6.636 143.822 1.00 4.19 ? 239 VAL N CG2 1 ATOM 1266 N N . VAL A 1 161 ? 51.575 8.983 141.499 1.00 4.92 ? 240 VAL N N 1 ATOM 1267 C CA . VAL A 1 161 ? 50.402 9.275 140.686 1.00 5.07 ? 240 VAL N CA 1 ATOM 1268 C C . VAL A 1 161 ? 50.388 8.434 139.405 1.00 6.63 ? 240 VAL N C 1 ATOM 1269 O O . VAL A 1 161 ? 51.273 8.537 138.544 1.00 6.22 ? 240 VAL N O 1 ATOM 1270 C CB . VAL A 1 161 ? 50.424 10.812 140.404 1.00 3.70 ? 240 VAL N CB 1 ATOM 1271 C CG1 . VAL A 1 161 ? 49.428 11.125 139.290 1.00 2.06 ? 240 VAL N CG1 1 ATOM 1272 C CG2 . VAL A 1 161 ? 50.023 11.623 141.650 1.00 2.00 ? 240 VAL N CG2 1 ATOM 1273 N N . PHE A 1 162 ? 49.358 7.594 139.374 1.00 7.65 ? 241 PHE N N 1 ATOM 1274 C CA . PHE A 1 162 ? 49.072 6.557 138.378 1.00 7.07 ? 241 PHE N CA 1 ATOM 1275 C C . PHE A 1 162 ? 47.829 6.855 137.564 1.00 7.54 ? 241 PHE N C 1 ATOM 1276 O O . PHE A 1 162 ? 46.775 7.050 138.161 1.00 8.56 ? 241 PHE N O 1 ATOM 1277 C CB . PHE A 1 162 ? 48.820 5.197 139.042 1.00 8.69 ? 241 PHE N CB 1 ATOM 1278 C CG . PHE A 1 162 ? 50.025 4.421 139.523 1.00 9.71 ? 241 PHE N CG 1 ATOM 1279 C CD1 . PHE A 1 162 ? 50.722 3.647 138.610 1.00 9.84 ? 241 PHE N CD1 1 ATOM 1280 C CD2 . PHE A 1 162 ? 50.388 4.445 140.846 1.00 9.28 ? 241 PHE N CD2 1 ATOM 1281 C CE1 . PHE A 1 162 ? 51.792 2.879 139.022 1.00 8.43 ? 241 PHE N CE1 1 ATOM 1282 C CE2 . PHE A 1 162 ? 51.458 3.671 141.246 1.00 9.51 ? 241 PHE N CE2 1 ATOM 1283 C CZ . PHE A 1 162 ? 52.159 2.889 140.349 1.00 8.40 ? 241 PHE N CZ 1 ATOM 1284 N N . THR A 1 163 ? 47.844 6.845 136.253 1.00 6.59 ? 242 THR N N 1 ATOM 1285 C CA . THR A 1 163 ? 46.606 7.047 135.520 1.00 8.51 ? 242 THR N CA 1 ATOM 1286 C C . THR A 1 163 ? 46.310 5.924 134.570 1.00 7.83 ? 242 THR N C 1 ATOM 1287 O O . THR A 1 163 ? 47.187 5.612 133.783 1.00 9.47 ? 242 THR N O 1 ATOM 1288 C CB . THR A 1 163 ? 46.680 8.342 134.750 1.00 11.19 ? 242 THR N CB 1 ATOM 1289 O OG1 . THR A 1 163 ? 47.076 9.373 135.681 1.00 14.75 ? 242 THR N OG1 1 ATOM 1290 C CG2 . THR A 1 163 ? 45.346 8.622 134.054 1.00 10.45 ? 242 THR N CG2 1 ATOM 1291 N N . ASP A 1 164 ? 45.186 5.243 134.696 1.00 6.98 ? 243 ASP N N 1 ATOM 1292 C CA . ASP A 1 164 ? 44.827 4.208 133.742 1.00 7.25 ? 243 ASP N CA 1 ATOM 1293 C C . ASP A 1 164 ? 43.592 4.729 133.088 1.00 9.69 ? 243 ASP N C 1 ATOM 1294 O O . ASP A 1 164 ? 42.846 5.395 133.783 1.00 11.29 ? 243 ASP N O 1 ATOM 1295 C CB . ASP A 1 164 ? 44.447 2.933 134.414 1.00 4.48 ? 243 ASP N CB 1 ATOM 1296 C CG . ASP A 1 164 ? 44.387 1.664 133.566 1.00 5.76 ? 243 ASP N CG 1 ATOM 1297 O OD1 . ASP A 1 164 ? 44.137 1.726 132.353 1.00 5.05 ? 243 ASP N OD1 1 ATOM 1298 O OD2 . ASP A 1 164 ? 44.596 0.592 134.156 1.00 7.39 ? 243 ASP N OD2 1 ATOM 1299 N N . GLY A 1 165 ? 43.263 4.507 131.838 1.00 10.46 ? 244 GLY N N 1 ATOM 1300 C CA . GLY A 1 165 ? 42.039 5.036 131.289 1.00 12.26 ? 244 GLY N CA 1 ATOM 1301 C C . GLY A 1 165 ? 42.352 5.662 129.948 1.00 13.49 ? 244 GLY N C 1 ATOM 1302 O O . GLY A 1 165 ? 43.347 5.280 129.316 1.00 14.63 ? 244 GLY N O 1 ATOM 1303 N N . SER A 1 166 ? 41.542 6.637 129.502 1.00 15.07 ? 245 SER N N 1 ATOM 1304 C CA . SER A 1 166 ? 41.683 7.172 128.174 1.00 18.60 ? 245 SER N CA 1 ATOM 1305 C C . SER A 1 166 ? 42.418 8.470 128.275 1.00 18.96 ? 245 SER N C 1 ATOM 1306 O O . SER A 1 166 ? 42.171 9.241 129.194 1.00 20.58 ? 245 SER N O 1 ATOM 1307 C CB . SER A 1 166 ? 40.325 7.389 127.592 1.00 23.49 ? 245 SER N CB 1 ATOM 1308 O OG . SER A 1 166 ? 40.401 7.758 126.218 1.00 31.50 ? 245 SER N OG 1 ATOM 1309 N N . ALA A 1 167 ? 43.285 8.700 127.291 1.00 17.63 ? 246 ALA N N 1 ATOM 1310 C CA . ALA A 1 167 ? 44.037 9.942 127.181 1.00 19.47 ? 246 ALA N CA 1 ATOM 1311 C C . ALA A 1 167 ? 43.279 10.952 126.350 1.00 21.81 ? 246 ALA N C 1 ATOM 1312 O O . ALA A 1 167 ? 43.733 12.057 126.048 1.00 24.70 ? 246 ALA N O 1 ATOM 1313 C CB . ALA A 1 167 ? 45.355 9.738 126.484 1.00 17.91 ? 246 ALA N CB 1 ATOM 1314 N N . THR A 1 168 ? 42.119 10.525 125.920 1.00 22.11 ? 247 THR N N 1 ATOM 1315 C CA . THR A 1 168 ? 41.272 11.276 125.057 1.00 23.24 ? 247 THR N CA 1 ATOM 1316 C C . THR A 1 168 ? 39.991 11.462 125.851 1.00 24.07 ? 247 THR N C 1 ATOM 1317 O O . THR A 1 168 ? 39.177 12.299 125.486 1.00 26.43 ? 247 THR N O 1 ATOM 1318 C CB . THR A 1 168 ? 41.266 10.350 123.801 1.00 24.19 ? 247 THR N CB 1 ATOM 1319 O OG1 . THR A 1 168 ? 42.225 10.985 122.970 1.00 26.43 ? 247 THR N OG1 1 ATOM 1320 C CG2 . THR A 1 168 ? 39.936 10.076 123.120 1.00 27.20 ? 247 THR N CG2 1 ATOM 1321 N N . GLY A 1 169 ? 39.742 10.790 126.967 1.00 23.77 ? 248 GLY N N 1 ATOM 1322 C CA . GLY A 1 169 ? 38.445 10.931 127.603 1.00 22.20 ? 248 GLY N CA 1 ATOM 1323 C C . GLY A 1 169 ? 38.634 11.337 129.046 1.00 21.34 ? 248 GLY N C 1 ATOM 1324 O O . GLY A 1 169 ? 39.692 11.834 129.431 1.00 21.72 ? 248 GLY N O 1 ATOM 1325 N N . PRO A 1 170 ? 37.654 11.127 129.902 1.00 21.14 ? 249 PRO N N 1 ATOM 1326 C CA . PRO A 1 170 ? 37.896 10.753 131.269 1.00 21.91 ? 249 PRO N CA 1 ATOM 1327 C C . PRO A 1 170 ? 38.775 9.521 131.381 1.00 22.82 ? 249 PRO N C 1 ATOM 1328 O O . PRO A 1 170 ? 38.519 8.518 130.712 1.00 24.57 ? 249 PRO N O 1 ATOM 1329 C CB . PRO A 1 170 ? 36.542 10.532 131.821 1.00 20.98 ? 249 PRO N CB 1 ATOM 1330 C CG . PRO A 1 170 ? 35.700 11.475 131.024 1.00 21.11 ? 249 PRO N CG 1 ATOM 1331 C CD . PRO A 1 170 ? 36.248 11.312 129.633 1.00 21.03 ? 249 PRO N CD 1 ATOM 1332 N N . ALA A 1 171 ? 39.841 9.613 132.173 1.00 20.79 ? 250 ALA N N 1 ATOM 1333 C CA . ALA A 1 171 ? 40.670 8.472 132.531 1.00 18.01 ? 250 ALA N CA 1 ATOM 1334 C C . ALA A 1 171 ? 40.374 8.269 134.008 1.00 17.24 ? 250 ALA N C 1 ATOM 1335 O O . ALA A 1 171 ? 39.607 9.001 134.661 1.00 18.13 ? 250 ALA N O 1 ATOM 1336 C CB . ALA A 1 171 ? 42.150 8.757 132.406 1.00 16.07 ? 250 ALA N CB 1 ATOM 1337 N N . GLU A 1 172 ? 41.044 7.284 134.562 1.00 16.52 ? 251 GLU N N 1 ATOM 1338 C CA . GLU A 1 172 ? 40.865 6.889 135.929 1.00 16.69 ? 251 GLU N CA 1 ATOM 1339 C C . GLU A 1 172 ? 42.152 7.023 136.742 1.00 14.68 ? 251 GLU N C 1 ATOM 1340 O O . GLU A 1 172 ? 42.869 6.038 136.983 1.00 14.74 ? 251 GLU N O 1 ATOM 1341 C CB . GLU A 1 172 ? 40.389 5.492 135.867 1.00 17.65 ? 251 GLU N CB 1 ATOM 1342 C CG . GLU A 1 172 ? 38.973 5.237 136.240 1.00 19.16 ? 251 GLU N CG 1 ATOM 1343 C CD . GLU A 1 172 ? 39.034 3.869 136.884 1.00 21.47 ? 251 GLU N CD 1 ATOM 1344 O OE1 . GLU A 1 172 ? 39.473 3.821 138.040 1.00 25.03 ? 251 GLU N OE1 1 ATOM 1345 O OE2 . GLU A 1 172 ? 38.699 2.874 136.220 1.00 22.58 ? 251 GLU N OE2 1 ATOM 1346 N N . THR A 1 173 ? 42.476 8.258 137.138 1.00 10.52 ? 252 THR N N 1 ATOM 1347 C CA . THR A 1 173 ? 43.708 8.517 137.879 1.00 8.02 ? 252 THR N CA 1 ATOM 1348 C C . THR A 1 173 ? 43.567 8.036 139.325 1.00 9.35 ? 252 THR N C 1 ATOM 1349 O O . THR A 1 173 ? 42.432 7.924 139.811 1.00 11.01 ? 252 THR N O 1 ATOM 1350 C CB . THR A 1 173 ? 44.048 10.063 137.829 1.00 5.40 ? 252 THR N CB 1 ATOM 1351 O OG1 . THR A 1 173 ? 44.264 10.484 136.484 1.00 4.84 ? 252 THR N OG1 1 ATOM 1352 C CG2 . THR A 1 173 ? 45.317 10.369 138.590 1.00 7.93 ? 252 THR N CG2 1 ATOM 1353 N N . ARG A 1 174 ? 44.686 7.707 139.988 1.00 9.43 ? 253 ARG N N 1 ATOM 1354 C CA . ARG A 1 174 ? 44.741 7.446 141.418 1.00 10.77 ? 253 ARG N CA 1 ATOM 1355 C C . ARG A 1 174 ? 46.097 7.560 142.080 1.00 10.53 ? 253 ARG N C 1 ATOM 1356 O O . ARG A 1 174 ? 47.131 7.104 141.581 1.00 10.72 ? 253 ARG N O 1 ATOM 1357 C CB . ARG A 1 174 ? 44.195 6.085 141.780 1.00 10.02 ? 253 ARG N CB 1 ATOM 1358 C CG . ARG A 1 174 ? 44.481 4.873 140.954 1.00 10.53 ? 253 ARG N CG 1 ATOM 1359 C CD . ARG A 1 174 ? 43.129 4.164 141.100 1.00 12.12 ? 253 ARG N CD 1 ATOM 1360 N NE . ARG A 1 174 ? 43.221 2.785 141.556 1.00 13.67 ? 253 ARG N NE 1 ATOM 1361 C CZ . ARG A 1 174 ? 42.211 1.935 141.338 1.00 13.91 ? 253 ARG N CZ 1 ATOM 1362 N NH1 . ARG A 1 174 ? 41.064 2.297 140.705 1.00 12.24 ? 253 ARG N NH1 1 ATOM 1363 N NH2 . ARG A 1 174 ? 42.375 0.681 141.767 1.00 13.87 ? 253 ARG N NH2 1 ATOM 1364 N N . ILE A 1 175 ? 46.058 8.270 143.208 1.00 11.61 ? 254 ILE N N 1 ATOM 1365 C CA . ILE A 1 175 ? 47.240 8.490 144.011 1.00 13.31 ? 254 ILE N CA 1 ATOM 1366 C C . ILE A 1 175 ? 47.428 7.243 144.877 1.00 12.94 ? 254 ILE N C 1 ATOM 1367 O O . ILE A 1 175 ? 46.507 6.744 145.519 1.00 15.33 ? 254 ILE N O 1 ATOM 1368 C CB . ILE A 1 175 ? 47.085 9.767 144.922 1.00 13.88 ? 254 ILE N CB 1 ATOM 1369 C CG1 . ILE A 1 175 ? 47.027 11.082 144.182 1.00 14.30 ? 254 ILE N CG1 1 ATOM 1370 C CG2 . ILE A 1 175 ? 48.362 9.902 145.744 1.00 14.74 ? 254 ILE N CG2 1 ATOM 1371 C CD1 . ILE A 1 175 ? 45.995 11.242 143.080 1.00 17.00 ? 254 ILE N CD1 1 ATOM 1372 N N . TYR A 1 176 ? 48.605 6.654 144.808 1.00 11.02 ? 255 TYR N N 1 ATOM 1373 C CA . TYR A 1 176 ? 48.985 5.526 145.625 1.00 9.17 ? 255 TYR N CA 1 ATOM 1374 C C . TYR A 1 176 ? 50.031 5.996 146.648 1.00 9.98 ? 255 TYR N C 1 ATOM 1375 O O . TYR A 1 176 ? 50.762 6.972 146.433 1.00 12.78 ? 255 TYR N O 1 ATOM 1376 C CB . TYR A 1 176 ? 49.544 4.445 144.708 1.00 7.71 ? 255 TYR N CB 1 ATOM 1377 C CG . TYR A 1 176 ? 48.527 3.414 144.185 1.00 5.70 ? 255 TYR N CG 1 ATOM 1378 C CD1 . TYR A 1 176 ? 47.598 3.696 143.166 1.00 6.67 ? 255 TYR N CD1 1 ATOM 1379 C CD2 . TYR A 1 176 ? 48.527 2.152 144.769 1.00 6.13 ? 255 TYR N CD2 1 ATOM 1380 C CE1 . TYR A 1 176 ? 46.688 2.716 142.761 1.00 7.74 ? 255 TYR N CE1 1 ATOM 1381 C CE2 . TYR A 1 176 ? 47.633 1.184 144.366 1.00 7.03 ? 255 TYR N CE2 1 ATOM 1382 C CZ . TYR A 1 176 ? 46.724 1.471 143.374 1.00 6.70 ? 255 TYR N CZ 1 ATOM 1383 O OH . TYR A 1 176 ? 45.825 0.487 143.017 1.00 5.33 ? 255 TYR N OH 1 ATOM 1384 N N . TYR A 1 177 ? 50.108 5.341 147.811 1.00 11.01 ? 256 TYR N N 1 ATOM 1385 C CA . TYR A 1 177 ? 51.008 5.703 148.904 1.00 10.22 ? 256 TYR N CA 1 ATOM 1386 C C . TYR A 1 177 ? 51.844 4.494 149.256 1.00 12.15 ? 256 TYR N C 1 ATOM 1387 O O . TYR A 1 177 ? 51.359 3.523 149.833 1.00 15.49 ? 256 TYR N O 1 ATOM 1388 C CB . TYR A 1 177 ? 50.235 6.139 150.164 1.00 10.18 ? 256 TYR N CB 1 ATOM 1389 C CG . TYR A 1 177 ? 49.463 7.410 149.902 1.00 9.98 ? 256 TYR N CG 1 ATOM 1390 C CD1 . TYR A 1 177 ? 48.173 7.354 149.393 1.00 8.97 ? 256 TYR N CD1 1 ATOM 1391 C CD2 . TYR A 1 177 ? 50.055 8.643 150.118 1.00 9.89 ? 256 TYR N CD2 1 ATOM 1392 C CE1 . TYR A 1 177 ? 47.489 8.529 149.098 1.00 7.61 ? 256 TYR N CE1 1 ATOM 1393 C CE2 . TYR A 1 177 ? 49.365 9.817 149.826 1.00 8.18 ? 256 TYR N CE2 1 ATOM 1394 C CZ . TYR A 1 177 ? 48.090 9.759 149.316 1.00 9.02 ? 256 TYR N CZ 1 ATOM 1395 O OH . TYR A 1 177 ? 47.441 10.933 149.009 1.00 10.95 ? 256 TYR N OH 1 ATOM 1396 N N . PHE A 1 178 ? 53.108 4.535 148.920 1.00 12.34 ? 257 PHE N N 1 ATOM 1397 C CA . PHE A 1 178 ? 53.949 3.417 149.194 1.00 10.65 ? 257 PHE N CA 1 ATOM 1398 C C . PHE A 1 178 ? 54.739 3.741 150.454 1.00 13.11 ? 257 PHE N C 1 ATOM 1399 O O . PHE A 1 178 ? 55.004 4.915 150.737 1.00 14.58 ? 257 PHE N O 1 ATOM 1400 C CB . PHE A 1 178 ? 54.863 3.211 147.966 1.00 8.30 ? 257 PHE N CB 1 ATOM 1401 C CG . PHE A 1 178 ? 54.108 2.844 146.687 1.00 5.47 ? 257 PHE N CG 1 ATOM 1402 C CD1 . PHE A 1 178 ? 53.618 1.555 146.522 1.00 2.53 ? 257 PHE N CD1 1 ATOM 1403 C CD2 . PHE A 1 178 ? 53.835 3.819 145.738 1.00 6.80 ? 257 PHE N CD2 1 ATOM 1404 C CE1 . PHE A 1 178 ? 52.854 1.274 145.412 1.00 2.00 ? 257 PHE N CE1 1 ATOM 1405 C CE2 . PHE A 1 178 ? 53.069 3.530 144.633 1.00 5.51 ? 257 PHE N CE2 1 ATOM 1406 C CZ . PHE A 1 178 ? 52.583 2.259 144.484 1.00 4.47 ? 257 PHE N CZ 1 ATOM 1407 N N . LYS A 1 179 ? 55.013 2.753 151.292 1.00 16.91 ? 258 LYS N N 1 ATOM 1408 C CA . LYS A 1 179 ? 56.072 2.874 152.273 1.00 20.35 ? 258 LYS N CA 1 ATOM 1409 C C . LYS A 1 179 ? 56.789 1.546 152.115 1.00 19.96 ? 258 LYS N C 1 ATOM 1410 O O . LYS A 1 179 ? 56.173 0.473 152.156 1.00 23.44 ? 258 LYS N O 1 ATOM 1411 C CB . LYS A 1 179 ? 55.637 2.964 153.748 1.00 24.21 ? 258 LYS N CB 1 ATOM 1412 C CG . LYS A 1 179 ? 56.828 2.695 154.683 1.00 27.10 ? 258 LYS N CG 1 ATOM 1413 C CD . LYS A 1 179 ? 56.471 2.721 156.132 1.00 31.77 ? 258 LYS N CD 1 ATOM 1414 C CE . LYS A 1 179 ? 56.855 4.119 156.546 1.00 35.82 ? 258 LYS N CE 1 ATOM 1415 N NZ . LYS A 1 179 ? 55.898 4.683 157.482 1.00 43.64 ? 258 LYS N NZ 1 ATOM 1416 N N . GLU A 1 180 ? 58.117 1.620 151.937 1.00 18.55 ? 259 GLU N N 1 ATOM 1417 C CA . GLU A 1 180 ? 59.004 0.460 151.767 1.00 18.84 ? 259 GLU N CA 1 ATOM 1418 C C . GLU A 1 180 ? 58.530 -0.577 150.735 1.00 18.68 ? 259 GLU N C 1 ATOM 1419 O O . GLU A 1 180 ? 58.583 -1.792 150.927 1.00 19.91 ? 259 GLU N O 1 ATOM 1420 C CB . GLU A 1 180 ? 59.200 -0.192 153.140 1.00 19.66 ? 259 GLU N CB 1 ATOM 1421 C CG . GLU A 1 180 ? 60.460 0.215 153.882 1.00 21.40 ? 259 GLU N CG 1 ATOM 1422 C CD . GLU A 1 180 ? 60.666 -0.365 155.276 1.00 23.02 ? 259 GLU N CD 1 ATOM 1423 O OE1 . GLU A 1 180 ? 59.838 -1.146 155.739 1.00 25.32 ? 259 GLU N OE1 1 ATOM 1424 O OE2 . GLU A 1 180 ? 61.667 -0.004 155.901 1.00 25.43 ? 259 GLU N OE2 1 ATOM 1425 N N . GLY A 1 181 ? 58.104 -0.052 149.569 1.00 16.89 ? 260 GLY N N 1 ATOM 1426 C CA . GLY A 1 181 ? 57.507 -0.876 148.517 1.00 10.11 ? 260 GLY N CA 1 ATOM 1427 C C . GLY A 1 181 ? 56.069 -1.327 148.817 1.00 8.72 ? 260 GLY N C 1 ATOM 1428 O O . GLY A 1 181 ? 55.378 -1.611 147.860 1.00 6.37 ? 260 GLY N O 1 ATOM 1429 N N . LYS A 1 182 ? 55.490 -1.406 150.026 1.00 7.96 ? 261 LYS N N 1 ATOM 1430 C CA . LYS A 1 182 ? 54.133 -1.892 150.286 1.00 7.94 ? 261 LYS N CA 1 ATOM 1431 C C . LYS A 1 182 ? 53.113 -0.784 150.033 1.00 7.53 ? 261 LYS N C 1 ATOM 1432 O O . LYS A 1 182 ? 53.416 0.413 150.176 1.00 11.62 ? 261 LYS N O 1 ATOM 1433 C CB . LYS A 1 182 ? 54.061 -2.344 151.733 1.00 7.08 ? 261 LYS N CB 1 ATOM 1434 C CG . LYS A 1 182 ? 52.917 -3.291 151.993 1.00 6.33 ? 261 LYS N CG 1 ATOM 1435 C CD . LYS A 1 182 ? 52.846 -3.631 153.462 1.00 6.49 ? 261 LYS N CD 1 ATOM 1436 C CE . LYS A 1 182 ? 51.874 -4.782 153.572 1.00 7.12 ? 261 LYS N CE 1 ATOM 1437 N NZ . LYS A 1 182 ? 51.872 -5.317 154.916 1.00 8.43 ? 261 LYS N NZ 1 ATOM 1438 N N . ILE A 1 183 ? 51.864 -1.141 149.706 1.00 5.46 ? 262 ILE N N 1 ATOM 1439 C CA . ILE A 1 183 ? 50.869 -0.089 149.447 1.00 4.69 ? 262 ILE N CA 1 ATOM 1440 C C . ILE A 1 183 ? 50.201 0.323 150.736 1.00 4.82 ? 262 ILE N C 1 ATOM 1441 O O . ILE A 1 183 ? 49.425 -0.473 151.300 1.00 4.48 ? 262 ILE N O 1 ATOM 1442 C CB . ILE A 1 183 ? 49.731 -0.534 148.452 1.00 3.29 ? 262 ILE N CB 1 ATOM 1443 C CG1 . ILE A 1 183 ? 50.408 -0.951 147.152 1.00 2.72 ? 262 ILE N CG1 1 ATOM 1444 C CG2 . ILE A 1 183 ? 48.721 0.573 148.197 1.00 5.40 ? 262 ILE N CG2 1 ATOM 1445 C CD1 . ILE A 1 183 ? 49.506 -1.557 146.109 1.00 4.36 ? 262 ILE N CD1 1 ATOM 1446 N N . LEU A 1 184 ? 50.519 1.515 151.232 1.00 5.14 ? 263 LEU N N 1 ATOM 1447 C CA . LEU A 1 184 ? 49.780 2.016 152.372 1.00 5.45 ? 263 LEU N CA 1 ATOM 1448 C C . LEU A 1 184 ? 48.334 2.369 152.134 1.00 7.30 ? 263 LEU N C 1 ATOM 1449 O O . LEU A 1 184 ? 47.472 2.048 152.931 1.00 11.09 ? 263 LEU N O 1 ATOM 1450 C CB . LEU A 1 184 ? 50.404 3.235 152.940 1.00 4.79 ? 263 LEU N CB 1 ATOM 1451 C CG . LEU A 1 184 ? 51.658 3.007 153.725 1.00 4.93 ? 263 LEU N CG 1 ATOM 1452 C CD1 . LEU A 1 184 ? 51.655 4.105 154.731 1.00 4.58 ? 263 LEU N CD1 1 ATOM 1453 C CD2 . LEU A 1 184 ? 51.692 1.703 154.511 1.00 5.16 ? 263 LEU N CD2 1 ATOM 1454 N N . LYS A 1 185 ? 47.965 3.022 151.061 1.00 6.78 ? 264 LYS N N 1 ATOM 1455 C CA . LYS A 1 185 ? 46.596 3.417 150.821 1.00 6.50 ? 264 LYS N CA 1 ATOM 1456 C C . LYS A 1 185 ? 46.620 3.746 149.350 1.00 7.84 ? 264 LYS N C 1 ATOM 1457 O O . LYS A 1 185 ? 47.702 3.798 148.767 1.00 6.91 ? 264 LYS N O 1 ATOM 1458 C CB . LYS A 1 185 ? 46.352 4.635 151.666 1.00 5.37 ? 264 LYS N CB 1 ATOM 1459 C CG . LYS A 1 185 ? 45.018 5.330 151.704 1.00 3.21 ? 264 LYS N CG 1 ATOM 1460 C CD . LYS A 1 185 ? 45.369 6.635 152.399 1.00 2.70 ? 264 LYS N CD 1 ATOM 1461 C CE . LYS A 1 185 ? 44.208 7.538 152.902 1.00 2.01 ? 264 LYS N CE 1 ATOM 1462 N NZ . LYS A 1 185 ? 43.267 7.855 151.839 1.00 5.66 ? 264 LYS N NZ 1 ATOM 1463 N N . TRP A 1 186 ? 45.486 3.934 148.697 1.00 9.12 ? 265 TRP N N 1 ATOM 1464 C CA . TRP A 1 186 ? 45.432 4.486 147.373 1.00 11.04 ? 265 TRP N CA 1 ATOM 1465 C C . TRP A 1 186 ? 44.081 5.195 147.351 1.00 14.06 ? 265 TRP N C 1 ATOM 1466 O O . TRP A 1 186 ? 43.084 4.708 147.896 1.00 18.74 ? 265 TRP N O 1 ATOM 1467 C CB . TRP A 1 186 ? 45.543 3.361 146.368 1.00 8.24 ? 265 TRP N CB 1 ATOM 1468 C CG . TRP A 1 186 ? 44.317 2.480 146.168 1.00 7.67 ? 265 TRP N CG 1 ATOM 1469 C CD1 . TRP A 1 186 ? 44.278 1.199 146.668 1.00 7.67 ? 265 TRP N CD1 1 ATOM 1470 C CD2 . TRP A 1 186 ? 43.160 2.828 145.489 1.00 7.13 ? 265 TRP N CD2 1 ATOM 1471 N NE1 . TRP A 1 186 ? 43.093 0.754 146.289 1.00 8.21 ? 265 TRP N NE1 1 ATOM 1472 C CE2 . TRP A 1 186 ? 42.412 1.689 145.592 1.00 7.98 ? 265 TRP N CE2 1 ATOM 1473 C CE3 . TRP A 1 186 ? 42.649 3.912 144.820 1.00 5.90 ? 265 TRP N CE3 1 ATOM 1474 C CZ2 . TRP A 1 186 ? 41.157 1.655 145.029 1.00 6.78 ? 265 TRP N CZ2 1 ATOM 1475 C CZ3 . TRP A 1 186 ? 41.388 3.870 144.264 1.00 6.78 ? 265 TRP N CZ3 1 ATOM 1476 C CH2 . TRP A 1 186 ? 40.641 2.736 144.362 1.00 5.88 ? 265 TRP N CH2 1 ATOM 1477 N N . GLU A 1 187 ? 43.997 6.327 146.698 1.00 13.51 ? 266 GLU N N 1 ATOM 1478 C CA . GLU A 1 187 ? 42.768 7.076 146.666 1.00 12.81 ? 266 GLU N CA 1 ATOM 1479 C C . GLU A 1 187 ? 42.607 7.639 145.271 1.00 13.14 ? 266 GLU N C 1 ATOM 1480 O O . GLU A 1 187 ? 43.618 7.911 144.625 1.00 15.75 ? 266 GLU N O 1 ATOM 1481 C CB . GLU A 1 187 ? 42.820 8.193 147.714 1.00 12.34 ? 266 GLU N CB 1 ATOM 1482 C CG . GLU A 1 187 ? 43.813 9.343 147.543 1.00 14.10 ? 266 GLU N CG 1 ATOM 1483 C CD . GLU A 1 187 ? 43.635 10.394 148.629 1.00 15.88 ? 266 GLU N CD 1 ATOM 1484 O OE1 . GLU A 1 187 ? 42.503 10.830 148.815 1.00 16.37 ? 266 GLU N OE1 1 ATOM 1485 O OE2 . GLU A 1 187 ? 44.604 10.808 149.269 1.00 18.95 ? 266 GLU N OE2 1 ATOM 1486 N N . PRO A 1 188 ? 41.386 7.763 144.749 1.00 12.48 ? 267 PRO N N 1 ATOM 1487 C CA . PRO A 1 188 ? 41.029 8.392 143.468 1.00 11.83 ? 267 PRO N CA 1 ATOM 1488 C C . PRO A 1 188 ? 41.238 9.868 143.225 1.00 11.18 ? 267 PRO N C 1 ATOM 1489 O O . PRO A 1 188 ? 41.150 10.639 144.170 1.00 14.28 ? 267 PRO N O 1 ATOM 1490 C CB . PRO A 1 188 ? 39.611 8.057 143.327 1.00 10.76 ? 267 PRO N CB 1 ATOM 1491 C CG . PRO A 1 188 ? 39.175 8.029 144.771 1.00 10.68 ? 267 PRO N CG 1 ATOM 1492 C CD . PRO A 1 188 ? 40.228 7.151 145.335 1.00 11.25 ? 267 PRO N CD 1 ATOM 1493 N N . LEU A 1 189 ? 41.449 10.347 142.015 1.00 8.72 ? 268 LEU N N 1 ATOM 1494 C CA . LEU A 1 189 ? 41.686 11.780 141.887 1.00 8.92 ? 268 LEU N CA 1 ATOM 1495 C C . LEU A 1 189 ? 40.486 12.568 142.390 1.00 10.47 ? 268 LEU N C 1 ATOM 1496 O O . LEU A 1 189 ? 39.351 12.107 142.221 1.00 14.59 ? 268 LEU N O 1 ATOM 1497 C CB . LEU A 1 189 ? 41.982 12.179 140.402 1.00 7.07 ? 268 LEU N CB 1 ATOM 1498 C CG . LEU A 1 189 ? 42.658 13.530 140.062 1.00 4.32 ? 268 LEU N CG 1 ATOM 1499 C CD1 . LEU A 1 189 ? 41.631 14.651 140.001 1.00 2.18 ? 268 LEU N CD1 1 ATOM 1500 C CD2 . LEU A 1 189 ? 43.774 13.768 141.077 1.00 2.45 ? 268 LEU N CD2 1 ATOM 1501 N N . THR A 1 190 ? 40.818 13.678 143.051 1.00 9.92 ? 269 THR N N 1 ATOM 1502 C CA . THR A 1 190 ? 39.825 14.582 143.555 1.00 11.22 ? 269 THR N CA 1 ATOM 1503 C C . THR A 1 190 ? 40.239 16.015 143.390 1.00 12.77 ? 269 THR N C 1 ATOM 1504 O O . THR A 1 190 ? 41.409 16.348 143.567 1.00 13.70 ? 269 THR N O 1 ATOM 1505 C CB . THR A 1 190 ? 39.583 14.222 145.026 1.00 13.89 ? 269 THR N CB 1 ATOM 1506 O OG1 . THR A 1 190 ? 38.288 13.611 144.938 1.00 2.34 ? 269 THR N OG1 1 ATOM 1507 C CG2 . THR A 1 190 ? 39.637 15.373 146.080 1.00 2.16 ? 269 THR N CG2 1 ATOM 1508 N N . GLY A 1 191 ? 39.282 16.883 143.127 1.00 12.31 ? 270 GLY N N 1 ATOM 1509 C CA . GLY A 1 191 ? 39.583 18.276 142.936 1.00 9.62 ? 270 GLY N CA 1 ATOM 1510 C C . GLY A 1 191 ? 38.902 18.636 141.630 1.00 8.99 ? 270 GLY N C 1 ATOM 1511 O O . GLY A 1 191 ? 38.087 17.861 141.140 1.00 9.19 ? 270 GLY N O 1 ATOM 1512 N N . THR A 1 192 ? 39.220 19.780 141.043 1.00 9.17 ? 271 THR N N 1 ATOM 1513 C CA . THR A 1 192 ? 38.532 20.285 139.885 1.00 8.85 ? 271 THR N CA 1 ATOM 1514 C C . THR A 1 192 ? 39.247 19.887 138.619 1.00 10.24 ? 271 THR N C 1 ATOM 1515 O O . THR A 1 192 ? 38.719 20.013 137.521 1.00 11.04 ? 271 THR N O 1 ATOM 1516 C CB . THR A 1 192 ? 38.453 21.762 140.071 1.00 9.19 ? 271 THR N CB 1 ATOM 1517 O OG1 . THR A 1 192 ? 39.763 22.195 140.403 1.00 7.24 ? 271 THR N OG1 1 ATOM 1518 C CG2 . THR A 1 192 ? 37.535 22.140 141.187 1.00 5.67 ? 271 THR N CG2 1 ATOM 1519 N N . ALA A 1 193 ? 40.490 19.452 138.755 1.00 10.87 ? 272 ALA N N 1 ATOM 1520 C CA . ALA A 1 193 ? 41.197 18.842 137.649 1.00 11.65 ? 272 ALA N CA 1 ATOM 1521 C C . ALA A 1 193 ? 40.450 17.775 136.823 1.00 11.75 ? 272 ALA N C 1 ATOM 1522 O O . ALA A 1 193 ? 39.996 16.735 137.299 1.00 13.19 ? 272 ALA N O 1 ATOM 1523 C CB . ALA A 1 193 ? 42.439 18.259 138.210 1.00 11.42 ? 272 ALA N CB 1 ATOM 1524 N N . LYS A 1 194 ? 40.367 18.001 135.528 1.00 12.60 ? 273 LYS N N 1 ATOM 1525 C CA . LYS A 1 194 ? 39.648 17.094 134.683 1.00 14.72 ? 273 LYS N CA 1 ATOM 1526 C C . LYS A 1 194 ? 40.389 15.848 134.191 1.00 16.58 ? 273 LYS N C 1 ATOM 1527 O O . LYS A 1 194 ? 39.767 14.808 133.925 1.00 19.19 ? 273 LYS N O 1 ATOM 1528 C CB . LYS A 1 194 ? 39.114 17.896 133.514 1.00 16.04 ? 273 LYS N CB 1 ATOM 1529 C CG . LYS A 1 194 ? 37.727 18.491 133.720 1.00 20.18 ? 273 LYS N CG 1 ATOM 1530 C CD . LYS A 1 194 ? 37.758 19.631 134.724 1.00 22.81 ? 273 LYS N CD 1 ATOM 1531 C CE . LYS A 1 194 ? 36.451 20.451 134.898 1.00 23.28 ? 273 LYS N CE 1 ATOM 1532 N NZ . LYS A 1 194 ? 36.618 21.533 135.863 1.00 22.09 ? 273 LYS N NZ 1 ATOM 1533 N N . HIS A 1 195 ? 41.704 15.852 133.988 1.00 16.43 ? 274 HIS N N 1 ATOM 1534 C CA . HIS A 1 195 ? 42.418 14.672 133.504 1.00 15.75 ? 274 HIS N CA 1 ATOM 1535 C C . HIS A 1 195 ? 43.893 14.870 133.826 1.00 15.68 ? 274 HIS N C 1 ATOM 1536 O O . HIS A 1 195 ? 44.469 15.921 133.508 1.00 15.59 ? 274 HIS N O 1 ATOM 1537 C CB . HIS A 1 195 ? 42.188 14.516 131.986 1.00 15.89 ? 274 HIS N CB 1 ATOM 1538 C CG . HIS A 1 195 ? 42.917 13.399 131.241 1.00 16.90 ? 274 HIS N CG 1 ATOM 1539 N ND1 . HIS A 1 195 ? 44.224 13.207 131.063 1.00 17.28 ? 274 HIS N ND1 1 ATOM 1540 C CD2 . HIS A 1 195 ? 42.275 12.405 130.540 1.00 18.03 ? 274 HIS N CD2 1 ATOM 1541 C CE1 . HIS A 1 195 ? 44.398 12.162 130.288 1.00 19.27 ? 274 HIS N CE1 1 ATOM 1542 N NE2 . HIS A 1 195 ? 43.214 11.688 129.985 1.00 20.22 ? 274 HIS N NE2 1 ATOM 1543 N N . ILE A 1 196 ? 44.452 13.866 134.509 1.00 12.23 ? 275 ILE N N 1 ATOM 1544 C CA . ILE A 1 196 ? 45.843 13.832 134.898 1.00 11.15 ? 275 ILE N CA 1 ATOM 1545 C C . ILE A 1 196 ? 46.722 12.818 134.149 1.00 10.03 ? 275 ILE N C 1 ATOM 1546 O O . ILE A 1 196 ? 46.437 11.639 133.977 1.00 9.79 ? 275 ILE N O 1 ATOM 1547 C CB . ILE A 1 196 ? 45.835 13.634 136.466 1.00 11.71 ? 275 ILE N CB 1 ATOM 1548 C CG1 . ILE A 1 196 ? 45.837 14.984 137.199 1.00 12.81 ? 275 ILE N CG1 1 ATOM 1549 C CG2 . ILE A 1 196 ? 47.106 12.966 136.949 1.00 11.75 ? 275 ILE N CG2 1 ATOM 1550 C CD1 . ILE A 1 196 ? 44.570 15.786 137.144 1.00 10.93 ? 275 ILE N CD1 1 ATOM 1551 N N . GLU A 1 197 ? 47.837 13.375 133.698 1.00 9.28 ? 276 GLU N N 1 ATOM 1552 C CA . GLU A 1 197 ? 48.942 12.696 133.081 1.00 11.18 ? 276 GLU N CA 1 ATOM 1553 C C . GLU A 1 197 ? 50.346 13.234 133.534 1.00 11.38 ? 276 GLU N C 1 ATOM 1554 O O . GLU A 1 197 ? 50.523 14.381 133.979 1.00 15.07 ? 276 GLU N O 1 ATOM 1555 C CB . GLU A 1 197 ? 48.644 12.867 131.630 1.00 13.44 ? 276 GLU N CB 1 ATOM 1556 C CG . GLU A 1 197 ? 49.004 11.589 130.986 1.00 17.58 ? 276 GLU N CG 1 ATOM 1557 C CD . GLU A 1 197 ? 47.952 11.120 130.001 1.00 19.87 ? 276 GLU N CD 1 ATOM 1558 O OE1 . GLU A 1 197 ? 47.719 11.807 129.009 1.00 18.74 ? 276 GLU N OE1 1 ATOM 1559 O OE2 . GLU A 1 197 ? 47.375 10.059 130.228 1.00 23.72 ? 276 GLU N OE2 1 ATOM 1560 N N . GLU A 1 198 ? 51.369 12.370 133.465 1.00 7.35 ? 277 GLU N N 1 ATOM 1561 C CA . GLU A 1 198 ? 52.789 12.650 133.715 1.00 5.63 ? 277 GLU N CA 1 ATOM 1562 C C . GLU A 1 198 ? 53.195 13.714 134.734 1.00 6.14 ? 277 GLU N C 1 ATOM 1563 O O . GLU A 1 198 ? 53.829 14.753 134.469 1.00 6.63 ? 277 GLU N O 1 ATOM 1564 C CB . GLU A 1 198 ? 53.455 12.975 132.404 1.00 5.20 ? 277 GLU N CB 1 ATOM 1565 C CG . GLU A 1 198 ? 53.435 11.789 131.474 1.00 7.39 ? 277 GLU N CG 1 ATOM 1566 C CD . GLU A 1 198 ? 53.455 12.054 129.963 1.00 6.98 ? 277 GLU N CD 1 ATOM 1567 O OE1 . GLU A 1 198 ? 53.540 13.219 129.578 1.00 8.81 ? 277 GLU N OE1 1 ATOM 1568 O OE2 . GLU A 1 198 ? 53.369 11.087 129.191 1.00 7.72 ? 277 GLU N OE2 1 ATOM 1569 N N . CYS A 1 199 ? 52.833 13.439 135.970 1.00 7.88 ? 278 CYS N N 1 ATOM 1570 C CA . CYS A 1 199 ? 53.038 14.417 136.998 1.00 4.77 ? 278 CYS N CA 1 ATOM 1571 C C . CYS A 1 199 ? 54.462 14.711 137.399 1.00 4.84 ? 278 CYS N C 1 ATOM 1572 O O . CYS A 1 199 ? 55.240 13.780 137.529 1.00 2.56 ? 278 CYS N O 1 ATOM 1573 C CB . CYS A 1 199 ? 52.258 13.966 138.168 1.00 5.59 ? 278 CYS N CB 1 ATOM 1574 S SG . CYS A 1 199 ? 50.478 14.201 137.926 1.00 5.64 ? 278 CYS N SG 1 ATOM 1575 N N . SER A 1 200 ? 54.800 16.000 137.579 1.00 2.96 ? 279 SER N N 1 ATOM 1576 C CA . SER A 1 200 ? 56.120 16.421 137.981 1.00 2.11 ? 279 SER N CA 1 ATOM 1577 C C . SER A 1 200 ? 56.129 16.772 139.437 1.00 3.64 ? 279 SER N C 1 ATOM 1578 O O . SER A 1 200 ? 55.462 17.774 139.724 1.00 3.67 ? 279 SER N O 1 ATOM 1579 C CB . SER A 1 200 ? 56.524 17.625 137.201 1.00 2.61 ? 279 SER N CB 1 ATOM 1580 O OG . SER A 1 200 ? 57.187 17.252 136.018 1.00 5.45 ? 279 SER N OG 1 ATOM 1581 N N . CYS A 1 201 ? 56.819 16.095 140.375 1.00 2.97 ? 280 CYS N N 1 ATOM 1582 C CA . CYS A 1 201 ? 56.630 16.472 141.767 1.00 2.10 ? 280 CYS N CA 1 ATOM 1583 C C . CYS A 1 201 ? 57.850 16.948 142.526 1.00 2.22 ? 280 CYS N C 1 ATOM 1584 O O . CYS A 1 201 ? 58.933 16.439 142.330 1.00 4.87 ? 280 CYS N O 1 ATOM 1585 C CB . CYS A 1 201 ? 56.012 15.295 142.519 1.00 2.09 ? 280 CYS N CB 1 ATOM 1586 S SG . CYS A 1 201 ? 54.616 14.504 141.675 1.00 3.20 ? 280 CYS N SG 1 ATOM 1587 N N . TYR A 1 202 ? 57.753 17.988 143.352 1.00 2.09 ? 281 TYR N N 1 ATOM 1588 C CA . TYR A 1 202 ? 58.832 18.395 144.279 1.00 3.29 ? 281 TYR N CA 1 ATOM 1589 C C . TYR A 1 202 ? 58.204 18.440 145.682 1.00 4.29 ? 281 TYR N C 1 ATOM 1590 O O . TYR A 1 202 ? 56.986 18.651 145.829 1.00 4.20 ? 281 TYR N O 1 ATOM 1591 C CB . TYR A 1 202 ? 59.383 19.789 143.917 1.00 2.55 ? 281 TYR N CB 1 ATOM 1592 C CG . TYR A 1 202 ? 58.357 20.898 144.011 1.00 2.05 ? 281 TYR N CG 1 ATOM 1593 C CD1 . TYR A 1 202 ? 57.433 21.164 143.015 1.00 2.06 ? 281 TYR N CD1 1 ATOM 1594 C CD2 . TYR A 1 202 ? 58.430 21.690 145.131 1.00 3.88 ? 281 TYR N CD2 1 ATOM 1595 C CE1 . TYR A 1 202 ? 56.603 22.253 143.125 1.00 3.10 ? 281 TYR N CE1 1 ATOM 1596 C CE2 . TYR A 1 202 ? 57.602 22.786 145.267 1.00 3.31 ? 281 TYR N CE2 1 ATOM 1597 C CZ . TYR A 1 202 ? 56.712 23.041 144.259 1.00 3.24 ? 281 TYR N CZ 1 ATOM 1598 O OH . TYR A 1 202 ? 55.966 24.172 144.384 1.00 5.35 ? 281 TYR N OH 1 ATOM 1599 N N . GLY A 1 203 ? 59.008 18.251 146.721 1.00 5.14 ? 282 GLY N N 1 ATOM 1600 C CA . GLY A 1 203 ? 58.500 18.262 148.093 1.00 6.37 ? 282 GLY N CA 1 ATOM 1601 C C . GLY A 1 203 ? 59.127 19.406 148.890 1.00 8.87 ? 282 GLY N C 1 ATOM 1602 O O . GLY A 1 203 ? 60.311 19.748 148.746 1.00 11.18 ? 282 GLY N O 1 ATOM 1603 N N . GLU A 1 204 ? 58.319 20.099 149.675 1.00 8.01 ? 283 GLU N N 1 ATOM 1604 C CA . GLU A 1 204 ? 58.875 21.053 150.622 1.00 9.32 ? 283 GLU N CA 1 ATOM 1605 C C . GLU A 1 204 ? 57.847 21.174 151.686 1.00 9.94 ? 283 GLU N C 1 ATOM 1606 O O . GLU A 1 204 ? 56.652 20.945 151.454 1.00 9.18 ? 283 GLU N O 1 ATOM 1607 C CB . GLU A 1 204 ? 59.116 22.443 150.080 1.00 9.40 ? 283 GLU N CB 1 ATOM 1608 C CG . GLU A 1 204 ? 58.107 22.954 149.083 1.00 12.87 ? 283 GLU N CG 1 ATOM 1609 C CD . GLU A 1 204 ? 57.119 23.956 149.634 1.00 14.77 ? 283 GLU N CD 1 ATOM 1610 O OE1 . GLU A 1 204 ? 57.535 25.021 150.092 1.00 15.27 ? 283 GLU N OE1 1 ATOM 1611 O OE2 . GLU A 1 204 ? 55.929 23.661 149.589 1.00 17.63 ? 283 GLU N OE2 1 ATOM 1612 N N . GLN A 1 205 ? 58.444 21.358 152.872 1.00 10.98 ? 284 GLN N N 1 ATOM 1613 C CA . GLN A 1 205 ? 57.711 21.591 154.114 1.00 11.26 ? 284 GLN N CA 1 ATOM 1614 C C . GLN A 1 205 ? 56.683 20.514 154.379 1.00 13.68 ? 284 GLN N C 1 ATOM 1615 O O . GLN A 1 205 ? 55.528 20.804 154.684 1.00 15.27 ? 284 GLN N O 1 ATOM 1616 C CB . GLN A 1 205 ? 57.008 22.964 154.068 1.00 12.71 ? 284 GLN N CB 1 ATOM 1617 C CG . GLN A 1 205 ? 57.970 24.115 154.228 1.00 14.50 ? 284 GLN N CG 1 ATOM 1618 C CD . GLN A 1 205 ? 57.247 25.417 154.530 1.00 18.99 ? 284 GLN N CD 1 ATOM 1619 O OE1 . GLN A 1 205 ? 56.796 26.139 153.639 1.00 2.37 ? 284 GLN N OE1 1 ATOM 1620 N NE2 . GLN A 1 205 ? 57.100 25.764 155.812 1.00 2.43 ? 284 GLN N NE2 1 ATOM 1621 N N . ALA A 1 206 ? 57.072 19.257 154.258 1.00 12.83 ? 285 ALA N N 1 ATOM 1622 C CA . ALA A 1 206 ? 56.142 18.132 154.420 1.00 13.65 ? 285 ALA N CA 1 ATOM 1623 C C . ALA A 1 206 ? 54.858 18.103 153.554 1.00 14.92 ? 285 ALA N C 1 ATOM 1624 O O . ALA A 1 206 ? 53.825 17.530 153.934 1.00 16.22 ? 285 ALA N O 1 ATOM 1625 C CB . ALA A 1 206 ? 55.751 18.035 155.899 1.00 13.97 ? 285 ALA N CB 1 ATOM 1626 N N . GLY A 1 207 ? 54.921 18.674 152.349 1.00 15.37 ? 286 GLY N N 1 ATOM 1627 C CA . GLY A 1 207 ? 53.840 18.632 151.379 1.00 16.52 ? 286 GLY N CA 1 ATOM 1628 C C . GLY A 1 207 ? 54.465 18.341 150.036 1.00 16.21 ? 286 GLY N C 1 ATOM 1629 O O . GLY A 1 207 ? 55.620 18.739 149.825 1.00 17.03 ? 286 GLY N O 1 ATOM 1630 N N . VAL A 1 208 ? 53.809 17.574 149.163 1.00 13.90 ? 287 VAL N N 1 ATOM 1631 C CA . VAL A 1 208 ? 54.413 17.357 147.867 1.00 10.09 ? 287 VAL N CA 1 ATOM 1632 C C . VAL A 1 208 ? 53.487 17.963 146.810 1.00 8.84 ? 287 VAL N C 1 ATOM 1633 O O . VAL A 1 208 ? 52.262 17.835 146.886 1.00 9.28 ? 287 VAL N O 1 ATOM 1634 C CB . VAL A 1 208 ? 54.726 15.779 147.582 1.00 10.48 ? 287 VAL N CB 1 ATOM 1635 C CG1 . VAL A 1 208 ? 54.732 15.054 148.879 1.00 9.02 ? 287 VAL N CG1 1 ATOM 1636 C CG2 . VAL A 1 208 ? 53.736 15.052 146.688 1.00 12.15 ? 287 VAL N CG2 1 ATOM 1637 N N . THR A 1 209 ? 54.047 18.720 145.872 1.00 5.80 ? 288 THR N N 1 ATOM 1638 C CA . THR A 1 209 ? 53.302 19.343 144.791 1.00 5.86 ? 288 THR N CA 1 ATOM 1639 C C . THR A 1 209 ? 53.599 18.683 143.452 1.00 6.94 ? 288 THR N C 1 ATOM 1640 O O . THR A 1 209 ? 54.757 18.470 143.070 1.00 11.15 ? 288 THR N O 1 ATOM 1641 C CB . THR A 1 209 ? 53.669 20.805 144.626 1.00 5.72 ? 288 THR N CB 1 ATOM 1642 O OG1 . THR A 1 209 ? 53.948 21.342 145.911 1.00 11.44 ? 288 THR N OG1 1 ATOM 1643 C CG2 . THR A 1 209 ? 52.561 21.565 143.960 1.00 4.09 ? 288 THR N CG2 1 ATOM 1644 N N . CYS A 1 210 ? 52.552 18.351 142.734 1.00 6.07 ? 289 CYS N N 1 ATOM 1645 C CA . CYS A 1 210 ? 52.712 17.852 141.421 1.00 4.35 ? 289 CYS N CA 1 ATOM 1646 C C . CYS A 1 210 ? 52.068 18.783 140.417 1.00 6.85 ? 289 CYS N C 1 ATOM 1647 O O . CYS A 1 210 ? 50.997 19.348 140.641 1.00 9.54 ? 289 CYS N O 1 ATOM 1648 C CB . CYS A 1 210 ? 52.113 16.506 141.348 1.00 2.04 ? 289 CYS N CB 1 ATOM 1649 S SG . CYS A 1 210 ? 53.062 15.458 142.471 1.00 2.00 ? 289 CYS N SG 1 ATOM 1650 N N . THR A 1 211 ? 52.772 19.031 139.311 1.00 7.87 ? 290 THR N N 1 ATOM 1651 C CA . THR A 1 211 ? 52.303 19.840 138.201 1.00 6.42 ? 290 THR N CA 1 ATOM 1652 C C . THR A 1 211 ? 52.248 18.845 137.045 1.00 5.65 ? 290 THR N C 1 ATOM 1653 O O . THR A 1 211 ? 53.312 18.324 136.723 1.00 2.49 ? 290 THR N O 1 ATOM 1654 C CB . THR A 1 211 ? 53.336 20.902 137.983 1.00 7.82 ? 290 THR N CB 1 ATOM 1655 O OG1 . THR A 1 211 ? 53.625 21.558 139.238 1.00 11.13 ? 290 THR N OG1 1 ATOM 1656 C CG2 . THR A 1 211 ? 52.847 21.863 136.928 1.00 4.29 ? 290 THR N CG2 1 ATOM 1657 N N . CYS A 1 212 ? 51.100 18.561 136.442 1.00 3.85 ? 291 CYS N N 1 ATOM 1658 C CA . CYS A 1 212 ? 50.906 17.478 135.494 1.00 2.01 ? 291 CYS N CA 1 ATOM 1659 C C . CYS A 1 212 ? 50.567 17.946 134.074 1.00 3.75 ? 291 CYS N C 1 ATOM 1660 O O . CYS A 1 212 ? 50.872 19.085 133.711 1.00 2.02 ? 291 CYS N O 1 ATOM 1661 C CB . CYS A 1 212 ? 49.796 16.636 136.093 1.00 2.00 ? 291 CYS N CB 1 ATOM 1662 S SG . CYS A 1 212 ? 50.149 16.195 137.804 1.00 3.53 ? 291 CYS N SG 1 ATOM 1663 N N . ARG A 1 213 ? 49.803 17.160 133.296 1.00 6.17 ? 292 ARG N N 1 ATOM 1664 C CA . ARG A 1 213 ? 49.385 17.457 131.944 1.00 7.34 ? 292 ARG N CA 1 ATOM 1665 C C . ARG A 1 213 ? 47.933 17.067 131.778 1.00 10.46 ? 292 ARG N C 1 ATOM 1666 O O . ARG A 1 213 ? 47.564 15.966 132.185 1.00 10.19 ? 292 ARG N O 1 ATOM 1667 C CB . ARG A 1 213 ? 50.283 16.643 131.022 1.00 5.54 ? 292 ARG N CB 1 ATOM 1668 C CG . ARG A 1 213 ? 49.827 16.194 129.629 1.00 4.05 ? 292 ARG N CG 1 ATOM 1669 C CD . ARG A 1 213 ? 50.848 15.215 129.062 1.00 4.88 ? 292 ARG N CD 1 ATOM 1670 N NE . ARG A 1 213 ? 50.422 14.656 127.797 1.00 5.46 ? 292 ARG N NE 1 ATOM 1671 C CZ . ARG A 1 213 ? 51.306 14.314 126.856 1.00 6.62 ? 292 ARG N CZ 1 ATOM 1672 N NH1 . ARG A 1 213 ? 52.631 14.193 127.066 1.00 10.10 ? 292 ARG N NH1 1 ATOM 1673 N NH2 . ARG A 1 213 ? 50.841 13.924 125.674 1.00 10.61 ? 292 ARG N NH2 1 ATOM 1674 N N . ASP A 1 214 ? 47.064 17.902 131.210 1.00 13.24 ? 293 ASP N N 1 ATOM 1675 C CA . ASP A 1 214 ? 45.710 17.466 130.958 1.00 14.00 ? 293 ASP N CA 1 ATOM 1676 C C . ASP A 1 214 ? 45.843 17.250 129.488 1.00 15.49 ? 293 ASP N C 1 ATOM 1677 O O . ASP A 1 214 ? 46.203 18.144 128.684 1.00 16.96 ? 293 ASP N O 1 ATOM 1678 C CB . ASP A 1 214 ? 44.677 18.548 131.277 1.00 15.66 ? 293 ASP N CB 1 ATOM 1679 C CG . ASP A 1 214 ? 43.176 18.272 131.022 1.00 16.31 ? 293 ASP N CG 1 ATOM 1680 O OD1 . ASP A 1 214 ? 42.786 17.393 130.254 1.00 17.43 ? 293 ASP N OD1 1 ATOM 1681 O OD2 . ASP A 1 214 ? 42.337 19.006 131.533 1.00 15.30 ? 293 ASP N OD2 1 ATOM 1682 N N . ASN A 1 215 ? 45.509 16.021 129.166 1.00 13.92 ? 294 ASN N N 1 ATOM 1683 C CA . ASN A 1 215 ? 45.738 15.666 127.802 1.00 11.79 ? 294 ASN N CA 1 ATOM 1684 C C . ASN A 1 215 ? 44.526 16.122 127.096 1.00 11.34 ? 294 ASN N C 1 ATOM 1685 O O . ASN A 1 215 ? 44.712 17.092 126.367 1.00 11.25 ? 294 ASN N O 1 ATOM 1686 C CB . ASN A 1 215 ? 45.933 14.191 127.572 1.00 11.74 ? 294 ASN N CB 1 ATOM 1687 C CG . ASN A 1 215 ? 46.837 14.050 126.353 1.00 9.12 ? 294 ASN N CG 1 ATOM 1688 O OD1 . ASN A 1 215 ? 47.948 14.594 126.327 1.00 11.55 ? 294 ASN N OD1 1 ATOM 1689 N ND2 . ASN A 1 215 ? 46.337 13.342 125.338 1.00 7.21 ? 294 ASN N ND2 1 ATOM 1690 N N . TRP A 1 216 ? 43.372 15.574 127.500 1.00 11.30 ? 295 TRP N N 1 ATOM 1691 C CA . TRP A 1 216 ? 42.025 15.908 127.027 1.00 15.65 ? 295 TRP N CA 1 ATOM 1692 C C . TRP A 1 216 ? 41.846 17.395 126.705 1.00 17.33 ? 295 TRP N C 1 ATOM 1693 O O . TRP A 1 216 ? 42.296 17.826 125.647 1.00 19.03 ? 295 TRP N O 1 ATOM 1694 C CB . TRP A 1 216 ? 40.987 15.490 128.105 1.00 17.78 ? 295 TRP N CB 1 ATOM 1695 C CG . TRP A 1 216 ? 39.510 15.427 127.718 1.00 20.33 ? 295 TRP N CG 1 ATOM 1696 C CD1 . TRP A 1 216 ? 39.112 15.476 126.408 1.00 20.87 ? 295 TRP N CD1 1 ATOM 1697 C CD2 . TRP A 1 216 ? 38.446 15.260 128.585 1.00 21.61 ? 295 TRP N CD2 1 ATOM 1698 N NE1 . TRP A 1 216 ? 37.814 15.334 126.437 1.00 20.92 ? 295 TRP N NE1 1 ATOM 1699 C CE2 . TRP A 1 216 ? 37.369 15.198 127.703 1.00 21.66 ? 295 TRP N CE2 1 ATOM 1700 C CE3 . TRP A 1 216 ? 38.200 15.140 129.949 1.00 24.05 ? 295 TRP N CE3 1 ATOM 1701 C CZ2 . TRP A 1 216 ? 36.063 15.023 128.163 1.00 22.07 ? 295 TRP N CZ2 1 ATOM 1702 C CZ3 . TRP A 1 216 ? 36.901 14.967 130.404 1.00 24.98 ? 295 TRP N CZ3 1 ATOM 1703 C CH2 . TRP A 1 216 ? 35.843 14.908 129.521 1.00 23.72 ? 295 TRP N CH2 1 ATOM 1704 N N . GLN A 1 217 ? 41.289 18.243 127.583 1.00 19.03 ? 296 GLN N N 1 ATOM 1705 C CA . GLN A 1 217 ? 41.083 19.633 127.210 1.00 20.45 ? 296 GLN N CA 1 ATOM 1706 C C . GLN A 1 217 ? 42.201 20.594 127.602 1.00 19.71 ? 296 GLN N C 1 ATOM 1707 O O . GLN A 1 217 ? 42.417 21.540 126.848 1.00 21.12 ? 296 GLN N O 1 ATOM 1708 C CB . GLN A 1 217 ? 39.792 20.127 127.804 1.00 21.77 ? 296 GLN N CB 1 ATOM 1709 C CG . GLN A 1 217 ? 38.595 19.261 127.441 1.00 23.14 ? 296 GLN N CG 1 ATOM 1710 C CD . GLN A 1 217 ? 37.590 19.272 128.582 1.00 24.02 ? 296 GLN N CD 1 ATOM 1711 O OE1 . GLN A 1 217 ? 36.614 20.000 128.517 1.00 27.66 ? 296 GLN N OE1 1 ATOM 1712 N NE2 . GLN A 1 217 ? 37.749 18.515 129.668 1.00 21.14 ? 296 GLN N NE2 1 ATOM 1713 N N . GLY A 1 218 ? 42.992 20.409 128.671 1.00 19.40 ? 297 GLY N N 1 ATOM 1714 C CA . GLY A 1 218 ? 44.037 21.352 129.088 1.00 19.74 ? 297 GLY N CA 1 ATOM 1715 C C . GLY A 1 218 ? 45.244 21.721 128.208 1.00 16.79 ? 297 GLY N C 1 ATOM 1716 O O . GLY A 1 218 ? 45.922 20.933 127.414 1.00 17.86 ? 297 GLY N O 1 ATOM 1717 N N . SER A 1 219 ? 45.255 23.044 128.338 1.00 12.47 ? 298 SER N N 1 ATOM 1718 C CA . SER A 1 219 ? 46.329 23.900 127.915 1.00 9.61 ? 298 SER N CA 1 ATOM 1719 C C . SER A 1 219 ? 46.858 24.689 129.096 1.00 9.50 ? 298 SER N C 1 ATOM 1720 O O . SER A 1 219 ? 47.792 25.481 128.937 1.00 6.36 ? 298 SER N O 1 ATOM 1721 C CB . SER A 1 219 ? 45.853 24.844 126.878 1.00 9.01 ? 298 SER N CB 1 ATOM 1722 O OG . SER A 1 219 ? 45.786 24.143 125.643 1.00 9.24 ? 298 SER N OG 1 ATOM 1723 N N . ASN A 1 220 ? 46.276 24.480 130.284 1.00 9.81 ? 299 ASN N N 1 ATOM 1724 C CA . ASN A 1 220 ? 46.737 25.043 131.550 1.00 8.39 ? 299 ASN N CA 1 ATOM 1725 C C . ASN A 1 220 ? 46.909 23.783 132.368 1.00 7.59 ? 299 ASN N C 1 ATOM 1726 O O . ASN A 1 220 ? 46.097 22.855 132.265 1.00 2.99 ? 299 ASN N O 1 ATOM 1727 C CB . ASN A 1 220 ? 45.700 25.962 132.244 1.00 10.11 ? 299 ASN N CB 1 ATOM 1728 C CG . ASN A 1 220 ? 44.266 25.483 132.380 1.00 12.55 ? 299 ASN N CG 1 ATOM 1729 O OD1 . ASN A 1 220 ? 43.895 24.583 131.642 1.00 10.85 ? 299 ASN N OD1 1 ATOM 1730 N ND2 . ASN A 1 220 ? 43.394 26.002 133.225 1.00 13.66 ? 299 ASN N ND2 1 ATOM 1731 N N . ARG A 1 221 ? 47.996 23.665 133.115 1.00 9.32 ? 300 ARG N N 1 ATOM 1732 C CA . ARG A 1 221 ? 48.255 22.430 133.869 1.00 8.86 ? 300 ARG N CA 1 ATOM 1733 C C . ARG A 1 221 ? 47.460 22.206 135.163 1.00 8.80 ? 300 ARG N C 1 ATOM 1734 O O . ARG A 1 221 ? 47.104 23.135 135.903 1.00 8.37 ? 300 ARG N O 1 ATOM 1735 C CB . ARG A 1 221 ? 49.762 22.373 134.118 1.00 10.48 ? 300 ARG N CB 1 ATOM 1736 C CG . ARG A 1 221 ? 50.436 22.627 132.753 1.00 10.88 ? 300 ARG N CG 1 ATOM 1737 C CD . ARG A 1 221 ? 51.963 22.673 132.716 1.00 13.54 ? 300 ARG N CD 1 ATOM 1738 N NE . ARG A 1 221 ? 52.388 21.325 132.464 1.00 8.38 ? 300 ARG N NE 1 ATOM 1739 C CZ . ARG A 1 221 ? 52.741 20.905 131.265 1.00 6.65 ? 300 ARG N CZ 1 ATOM 1740 N NH1 . ARG A 1 221 ? 52.908 21.678 130.204 1.00 6.47 ? 300 ARG N NH1 1 ATOM 1741 N NH2 . ARG A 1 221 ? 53.002 19.638 131.163 1.00 4.88 ? 300 ARG N NH2 1 ATOM 1742 N N . PRO A 1 222 ? 47.034 20.970 135.424 1.00 8.46 ? 301 PRO N N 1 ATOM 1743 C CA . PRO A 1 222 ? 46.489 20.588 136.710 1.00 7.39 ? 301 PRO N CA 1 ATOM 1744 C C . PRO A 1 222 ? 47.610 20.477 137.720 1.00 7.03 ? 301 PRO N C 1 ATOM 1745 O O . PRO A 1 222 ? 48.678 19.944 137.438 1.00 10.13 ? 301 PRO N O 1 ATOM 1746 C CB . PRO A 1 222 ? 45.759 19.283 136.444 1.00 7.85 ? 301 PRO N CB 1 ATOM 1747 C CG . PRO A 1 222 ? 46.490 18.719 135.258 1.00 8.98 ? 301 PRO N CG 1 ATOM 1748 C CD . PRO A 1 222 ? 46.781 19.943 134.426 1.00 9.00 ? 301 PRO N CD 1 ATOM 1749 N N . VAL A 1 223 ? 47.348 20.964 138.914 1.00 6.13 ? 302 VAL N N 1 ATOM 1750 C CA . VAL A 1 223 ? 48.291 20.962 139.983 1.00 4.20 ? 302 VAL N CA 1 ATOM 1751 C C . VAL A 1 223 ? 47.625 20.055 140.971 1.00 6.50 ? 302 VAL N C 1 ATOM 1752 O O . VAL A 1 223 ? 46.433 20.179 141.166 1.00 4.14 ? 302 VAL N O 1 ATOM 1753 C CB . VAL A 1 223 ? 48.438 22.373 140.476 1.00 2.04 ? 302 VAL N CB 1 ATOM 1754 C CG1 . VAL A 1 223 ? 49.045 22.479 141.883 1.00 2.00 ? 302 VAL N CG1 1 ATOM 1755 C CG2 . VAL A 1 223 ? 49.381 23.015 139.478 1.00 2.15 ? 302 VAL N CG2 1 ATOM 1756 N N . ILE A 1 224 ? 48.306 19.074 141.496 1.00 8.18 ? 303 ILE N N 1 ATOM 1757 C CA . ILE A 1 224 ? 47.794 18.255 142.563 1.00 9.50 ? 303 ILE N CA 1 ATOM 1758 C C . ILE A 1 224 ? 48.616 18.577 143.820 1.00 11.61 ? 303 ILE N C 1 ATOM 1759 O O . ILE A 1 224 ? 49.832 18.389 143.772 1.00 14.18 ? 303 ILE N O 1 ATOM 1760 C CB . ILE A 1 224 ? 47.934 16.738 142.194 1.00 8.33 ? 303 ILE N CB 1 ATOM 1761 C CG1 . ILE A 1 224 ? 46.995 16.351 141.068 1.00 6.82 ? 303 ILE N CG1 1 ATOM 1762 C CG2 . ILE A 1 224 ? 47.623 15.871 143.418 1.00 6.62 ? 303 ILE N CG2 1 ATOM 1763 C CD1 . ILE A 1 224 ? 47.273 14.896 140.645 1.00 6.38 ? 303 ILE N CD1 1 ATOM 1764 N N . GLN A 1 225 ? 48.159 19.075 144.966 1.00 14.43 ? 304 GLN N N 1 ATOM 1765 C CA . GLN A 1 225 ? 49.030 19.031 146.136 1.00 16.93 ? 304 GLN N CA 1 ATOM 1766 C C . GLN A 1 225 ? 48.659 17.759 146.931 1.00 14.88 ? 304 GLN N C 1 ATOM 1767 O O . GLN A 1 225 ? 47.471 17.381 147.047 1.00 13.92 ? 304 GLN N O 1 ATOM 1768 C CB . GLN A 1 225 ? 48.852 20.214 147.043 1.00 23.71 ? 304 GLN N CB 1 ATOM 1769 C CG . GLN A 1 225 ? 47.718 21.149 146.761 1.00 31.91 ? 304 GLN N CG 1 ATOM 1770 C CD . GLN A 1 225 ? 48.206 22.336 145.981 1.00 39.27 ? 304 GLN N CD 1 ATOM 1771 O OE1 . GLN A 1 225 ? 47.687 22.696 144.931 1.00 2.78 ? 304 GLN N OE1 1 ATOM 1772 N NE2 . GLN A 1 225 ? 49.230 23.001 146.493 1.00 2.66 ? 304 GLN N NE2 1 ATOM 1773 N N . ILE A 1 226 ? 49.667 17.026 147.420 1.00 12.17 ? 305 ILE N N 1 ATOM 1774 C CA . ILE A 1 226 ? 49.469 15.806 148.199 1.00 9.30 ? 305 ILE N CA 1 ATOM 1775 C C . ILE A 1 226 ? 50.056 16.044 149.576 1.00 11.31 ? 305 ILE N C 1 ATOM 1776 O O . ILE A 1 226 ? 51.130 16.638 149.672 1.00 9.66 ? 305 ILE N O 1 ATOM 1777 C CB . ILE A 1 226 ? 50.208 14.565 147.590 1.00 7.08 ? 305 ILE N CB 1 ATOM 1778 C CG1 . ILE A 1 226 ? 49.677 14.218 146.238 1.00 6.04 ? 305 ILE N CG1 1 ATOM 1779 C CG2 . ILE A 1 226 ? 50.027 13.351 148.479 1.00 5.83 ? 305 ILE N CG2 1 ATOM 1780 C CD1 . ILE A 1 226 ? 50.601 13.196 145.539 1.00 6.22 ? 305 ILE N CD1 1 ATOM 1781 N N . ASP A 1 227 ? 49.411 15.542 150.623 1.00 13.02 ? 306 ASP N N 1 ATOM 1782 C CA . ASP A 1 227 ? 49.856 15.636 151.998 1.00 14.41 ? 306 ASP N CA 1 ATOM 1783 C C . ASP A 1 227 ? 50.283 14.218 152.347 1.00 14.88 ? 306 ASP N C 1 ATOM 1784 O O . ASP A 1 227 ? 49.413 13.388 152.664 1.00 13.47 ? 306 ASP N O 1 ATOM 1785 C CB . ASP A 1 227 ? 48.731 16.041 152.977 1.00 16.80 ? 306 ASP N CB 1 ATOM 1786 C CG . ASP A 1 227 ? 49.170 16.311 154.428 1.00 18.20 ? 306 ASP N CG 1 ATOM 1787 O OD1 . ASP A 1 227 ? 50.086 15.690 154.956 1.00 19.67 ? 306 ASP N OD1 1 ATOM 1788 O OD2 . ASP A 1 227 ? 48.587 17.176 155.073 1.00 19.36 ? 306 ASP N OD2 1 ATOM 1789 N N . PRO A 1 228 ? 51.607 13.945 152.386 1.00 15.21 ? 307 PRO N N 1 ATOM 1790 C CA . PRO A 1 228 ? 52.170 12.622 152.616 1.00 14.17 ? 307 PRO N CA 1 ATOM 1791 C C . PRO A 1 228 ? 52.029 12.151 154.068 1.00 16.03 ? 307 PRO N C 1 ATOM 1792 O O . PRO A 1 228 ? 52.059 10.949 154.358 1.00 17.46 ? 307 PRO N O 1 ATOM 1793 C CB . PRO A 1 228 ? 53.586 12.793 152.092 1.00 12.42 ? 307 PRO N CB 1 ATOM 1794 C CG . PRO A 1 228 ? 53.920 14.220 152.448 1.00 12.99 ? 307 PRO N CG 1 ATOM 1795 C CD . PRO A 1 228 ? 52.657 14.930 152.127 1.00 14.27 ? 307 PRO N CD 1 ATOM 1796 N N . VAL A 1 229 ? 51.819 13.104 154.992 1.00 17.18 ? 308 VAL N N 1 ATOM 1797 C CA . VAL A 1 229 ? 51.560 12.814 156.403 1.00 16.55 ? 308 VAL N CA 1 ATOM 1798 C C . VAL A 1 229 ? 50.155 12.264 156.613 1.00 16.47 ? 308 VAL N C 1 ATOM 1799 O O . VAL A 1 229 ? 49.974 11.290 157.320 1.00 17.25 ? 308 VAL N O 1 ATOM 1800 C CB . VAL A 1 229 ? 51.676 14.052 157.287 1.00 16.51 ? 308 VAL N CB 1 ATOM 1801 C CG1 . VAL A 1 229 ? 51.870 13.460 158.638 1.00 14.57 ? 308 VAL N CG1 1 ATOM 1802 C CG2 . VAL A 1 229 ? 52.791 15.053 156.910 1.00 16.56 ? 308 VAL N CG2 1 ATOM 1803 N N . ALA A 1 230 ? 49.125 12.884 156.035 1.00 16.40 ? 309 ALA N N 1 ATOM 1804 C CA . ALA A 1 230 ? 47.760 12.425 156.232 1.00 13.04 ? 309 ALA N CA 1 ATOM 1805 C C . ALA A 1 230 ? 47.193 11.619 155.086 1.00 11.81 ? 309 ALA N C 1 ATOM 1806 O O . ALA A 1 230 ? 46.111 11.050 155.162 1.00 15.40 ? 309 ALA N O 1 ATOM 1807 C CB . ALA A 1 230 ? 46.873 13.611 156.455 1.00 12.26 ? 309 ALA N CB 1 ATOM 1808 N N . MET A 1 231 ? 47.940 11.540 154.005 1.00 10.50 ? 310 MET N N 1 ATOM 1809 C CA . MET A 1 231 ? 47.549 10.828 152.805 1.00 9.02 ? 310 MET N CA 1 ATOM 1810 C C . MET A 1 231 ? 46.179 11.306 152.288 1.00 8.97 ? 310 MET N C 1 ATOM 1811 O O . MET A 1 231 ? 45.114 10.654 152.274 1.00 8.07 ? 310 MET N O 1 ATOM 1812 C CB . MET A 1 231 ? 47.608 9.330 153.161 1.00 9.76 ? 310 MET N CB 1 ATOM 1813 C CG . MET A 1 231 ? 49.014 8.815 153.568 1.00 9.36 ? 310 MET N CG 1 ATOM 1814 S SD . MET A 1 231 ? 49.008 7.094 154.139 1.00 12.43 ? 310 MET N SD 1 ATOM 1815 C CE . MET A 1 231 ? 49.950 7.313 155.618 1.00 14.05 ? 310 MET N CE 1 ATOM 1816 N N . THR A 1 232 ? 46.300 12.597 151.927 1.00 8.43 ? 311 THR N N 1 ATOM 1817 C CA . THR A 1 232 ? 45.208 13.329 151.333 1.00 10.35 ? 311 THR N CA 1 ATOM 1818 C C . THR A 1 232 ? 45.726 14.176 150.203 1.00 11.79 ? 311 THR N C 1 ATOM 1819 O O . THR A 1 232 ? 46.897 14.532 150.278 1.00 12.48 ? 311 THR N O 1 ATOM 1820 C CB . THR A 1 232 ? 44.616 14.289 152.240 1.00 9.51 ? 311 THR N CB 1 ATOM 1821 O OG1 . THR A 1 232 ? 44.858 13.889 153.565 1.00 14.32 ? 311 THR N OG1 1 ATOM 1822 C CG2 . THR A 1 232 ? 43.154 14.331 151.982 1.00 11.30 ? 311 THR N CG2 1 ATOM 1823 N N . HIS A 1 233 ? 44.900 14.600 149.223 1.00 11.66 ? 312 HIS N N 1 ATOM 1824 C CA . HIS A 1 233 ? 45.298 15.480 148.125 1.00 11.64 ? 312 HIS N CA 1 ATOM 1825 C C . HIS A 1 233 ? 44.120 16.317 147.609 1.00 13.74 ? 312 HIS N C 1 ATOM 1826 O O . HIS A 1 233 ? 42.972 16.028 147.981 1.00 12.64 ? 312 HIS N O 1 ATOM 1827 C CB . HIS A 1 233 ? 45.843 14.644 146.984 1.00 10.59 ? 312 HIS N CB 1 ATOM 1828 C CG . HIS A 1 233 ? 44.783 13.825 146.259 1.00 6.18 ? 312 HIS N CG 1 ATOM 1829 N ND1 . HIS A 1 233 ? 44.182 12.767 146.731 1.00 3.23 ? 312 HIS N ND1 1 ATOM 1830 C CD2 . HIS A 1 233 ? 44.284 14.082 145.009 1.00 4.39 ? 312 HIS N CD2 1 ATOM 1831 C CE1 . HIS A 1 233 ? 43.333 12.360 145.835 1.00 2.08 ? 312 HIS N CE1 1 ATOM 1832 N NE2 . HIS A 1 233 ? 43.395 13.155 144.799 1.00 3.56 ? 312 HIS N NE2 1 ATOM 1833 N N . THR A 1 234 ? 44.399 17.327 146.762 1.00 15.44 ? 313 THR N N 1 ATOM 1834 C CA . THR A 1 234 ? 43.383 18.072 146.014 1.00 17.49 ? 313 THR N CA 1 ATOM 1835 C C . THR A 1 234 ? 43.992 18.492 144.705 1.00 15.65 ? 313 THR N C 1 ATOM 1836 O O . THR A 1 234 ? 45.220 18.604 144.632 1.00 17.45 ? 313 THR N O 1 ATOM 1837 C CB . THR A 1 234 ? 42.886 19.394 146.614 1.00 20.59 ? 313 THR N CB 1 ATOM 1838 O OG1 . THR A 1 234 ? 43.967 19.970 147.324 1.00 23.73 ? 313 THR N OG1 1 ATOM 1839 C CG2 . THR A 1 234 ? 41.587 19.180 147.381 1.00 24.83 ? 313 THR N CG2 1 ATOM 1840 N N . SER A 1 235 ? 43.163 18.737 143.690 1.00 12.30 ? 314 SER N N 1 ATOM 1841 C CA . SER A 1 235 ? 43.659 19.228 142.440 1.00 10.34 ? 314 SER N CA 1 ATOM 1842 C C . SER A 1 235 ? 42.837 20.417 141.947 1.00 8.93 ? 314 SER N C 1 ATOM 1843 O O . SER A 1 235 ? 41.646 20.559 142.221 1.00 10.73 ? 314 SER N O 1 ATOM 1844 C CB . SER A 1 235 ? 43.624 18.091 141.466 1.00 8.99 ? 314 SER N CB 1 ATOM 1845 O OG . SER A 1 235 ? 42.268 17.715 141.271 1.00 13.69 ? 314 SER N OG 1 ATOM 1846 N N . GLN A 1 236 ? 43.502 21.219 141.144 1.00 7.88 ? 315 GLN N N 1 ATOM 1847 C CA . GLN A 1 236 ? 43.034 22.455 140.575 1.00 4.39 ? 315 GLN N CA 1 ATOM 1848 C C . GLN A 1 236 ? 43.899 22.720 139.321 1.00 3.97 ? 315 GLN N C 1 ATOM 1849 O O . GLN A 1 236 ? 44.787 21.925 138.982 1.00 2.95 ? 315 GLN N O 1 ATOM 1850 C CB . GLN A 1 236 ? 43.211 23.549 141.606 1.00 6.06 ? 315 GLN N CB 1 ATOM 1851 C CG . GLN A 1 236 ? 44.617 24.094 141.826 1.00 9.90 ? 315 GLN N CG 1 ATOM 1852 C CD . GLN A 1 236 ? 44.588 25.496 142.420 1.00 13.17 ? 315 GLN N CD 1 ATOM 1853 O OE1 . GLN A 1 236 ? 44.627 26.558 141.792 1.00 13.36 ? 315 GLN N OE1 1 ATOM 1854 N NE2 . GLN A 1 236 ? 44.467 25.481 143.733 1.00 12.02 ? 315 GLN N NE2 1 ATOM 1855 N N . TYR A 1 237 ? 43.663 23.780 138.567 1.00 2.23 ? 316 TYR N N 1 ATOM 1856 C CA . TYR A 1 237 ? 44.463 24.154 137.445 1.00 3.87 ? 316 TYR N CA 1 ATOM 1857 C C . TYR A 1 237 ? 45.203 25.344 137.980 1.00 5.88 ? 316 TYR N C 1 ATOM 1858 O O . TYR A 1 237 ? 44.931 25.829 139.072 1.00 7.40 ? 316 TYR N O 1 ATOM 1859 C CB . TYR A 1 237 ? 43.572 24.538 136.280 1.00 3.25 ? 316 TYR N CB 1 ATOM 1860 C CG . TYR A 1 237 ? 43.022 23.266 135.630 1.00 2.13 ? 316 TYR N CG 1 ATOM 1861 C CD1 . TYR A 1 237 ? 41.954 22.564 136.186 1.00 2.02 ? 316 TYR N CD1 1 ATOM 1862 C CD2 . TYR A 1 237 ? 43.682 22.777 134.494 1.00 3.28 ? 316 TYR N CD2 1 ATOM 1863 C CE1 . TYR A 1 237 ? 41.593 21.376 135.598 1.00 3.61 ? 316 TYR N CE1 1 ATOM 1864 C CE2 . TYR A 1 237 ? 43.327 21.582 133.902 1.00 4.51 ? 316 TYR N CE2 1 ATOM 1865 C CZ . TYR A 1 237 ? 42.285 20.909 134.485 1.00 4.06 ? 316 TYR N CZ 1 ATOM 1866 O OH . TYR A 1 237 ? 41.995 19.663 134.015 1.00 8.11 ? 316 TYR N OH 1 ATOM 1867 N N . ILE A 1 238 ? 46.195 25.785 137.245 1.00 6.21 ? 317 ILE N N 1 ATOM 1868 C CA . ILE A 1 238 ? 46.975 26.966 137.591 1.00 7.61 ? 317 ILE N CA 1 ATOM 1869 C C . ILE A 1 238 ? 46.165 28.140 137.095 1.00 8.58 ? 317 ILE N C 1 ATOM 1870 O O . ILE A 1 238 ? 45.909 28.205 135.886 1.00 10.64 ? 317 ILE N O 1 ATOM 1871 C CB . ILE A 1 238 ? 48.344 26.929 136.865 1.00 7.34 ? 317 ILE N CB 1 ATOM 1872 C CG1 . ILE A 1 238 ? 49.121 25.825 137.513 1.00 6.00 ? 317 ILE N CG1 1 ATOM 1873 C CG2 . ILE A 1 238 ? 49.092 28.278 136.871 1.00 5.60 ? 317 ILE N CG2 1 ATOM 1874 C CD1 . ILE A 1 238 ? 50.122 25.196 136.549 1.00 6.95 ? 317 ILE N CD1 1 ATOM 1875 N N . CYS A 1 239 ? 45.815 29.081 137.955 1.00 11.20 ? 318 CYS N N 1 ATOM 1876 C CA . CYS A 1 239 ? 45.117 30.282 137.537 1.00 11.09 ? 318 CYS N CA 1 ATOM 1877 C C . CYS A 1 239 ? 45.739 31.173 136.450 1.00 10.22 ? 318 CYS N C 1 ATOM 1878 O O . CYS A 1 239 ? 44.954 31.726 135.678 1.00 13.66 ? 318 CYS N O 1 ATOM 1879 C CB . CYS A 1 239 ? 44.899 31.149 138.706 1.00 11.43 ? 318 CYS N CB 1 ATOM 1880 S SG . CYS A 1 239 ? 43.938 30.444 140.097 1.00 12.16 ? 318 CYS N SG 1 ATOM 1881 N N . SER A 1 240 ? 47.065 31.337 136.287 1.00 8.32 ? 319 SER N N 1 ATOM 1882 C CA . SER A 1 240 ? 47.710 32.279 135.376 1.00 8.61 ? 319 SER N CA 1 ATOM 1883 C C . SER A 1 240 ? 47.255 32.277 133.918 1.00 9.42 ? 319 SER N C 1 ATOM 1884 O O . SER A 1 240 ? 46.995 31.205 133.366 1.00 9.73 ? 319 SER N O 1 ATOM 1885 C CB . SER A 1 240 ? 49.209 32.031 135.427 1.00 10.09 ? 319 SER N CB 1 ATOM 1886 O OG . SER A 1 240 ? 49.937 32.918 134.596 1.00 12.59 ? 319 SER N OG 1 ATOM 1887 N N . PRO A 1 241 ? 47.098 33.428 133.221 1.00 10.43 ? 320 PRO N N 1 ATOM 1888 C CA . PRO A 1 241 ? 46.956 33.488 131.778 1.00 9.04 ? 320 PRO N CA 1 ATOM 1889 C C . PRO A 1 241 ? 48.168 32.948 131.054 1.00 9.79 ? 320 PRO N C 1 ATOM 1890 O O . PRO A 1 241 ? 48.004 32.499 129.926 1.00 14.46 ? 320 PRO N O 1 ATOM 1891 C CB . PRO A 1 241 ? 46.667 34.933 131.451 1.00 9.18 ? 320 PRO N CB 1 ATOM 1892 C CG . PRO A 1 241 ? 47.144 35.711 132.638 1.00 8.74 ? 320 PRO N CG 1 ATOM 1893 C CD . PRO A 1 241 ? 46.904 34.762 133.788 1.00 9.46 ? 320 PRO N CD 1 ATOM 1894 N N . VAL A 1 242 ? 49.352 32.887 131.675 1.00 7.91 ? 321 VAL N N 1 ATOM 1895 C CA . VAL A 1 242 ? 50.547 32.309 131.070 1.00 6.02 ? 321 VAL N CA 1 ATOM 1896 C C . VAL A 1 242 ? 50.377 30.780 130.925 1.00 8.46 ? 321 VAL N C 1 ATOM 1897 O O . VAL A 1 242 ? 50.566 30.031 131.895 1.00 8.93 ? 321 VAL N O 1 ATOM 1898 C CB . VAL A 1 242 ? 51.766 32.690 131.948 1.00 6.12 ? 321 VAL N CB 1 ATOM 1899 C CG1 . VAL A 1 242 ? 53.083 32.154 131.373 1.00 5.64 ? 321 VAL N CG1 1 ATOM 1900 C CG2 . VAL A 1 242 ? 51.766 34.211 132.079 1.00 3.31 ? 321 VAL N CG2 1 ATOM 1901 N N . LEU A 1 243 ? 49.997 30.322 129.709 1.00 9.50 ? 322 LEU N N 1 ATOM 1902 C CA . LEU A 1 243 ? 49.692 28.931 129.420 1.00 7.87 ? 322 LEU N CA 1 ATOM 1903 C C . LEU A 1 243 ? 51.017 28.275 129.143 1.00 8.44 ? 322 LEU N C 1 ATOM 1904 O O . LEU A 1 243 ? 51.917 28.827 128.518 1.00 10.46 ? 322 LEU N O 1 ATOM 1905 C CB . LEU A 1 243 ? 48.760 28.824 128.214 1.00 5.33 ? 322 LEU N CB 1 ATOM 1906 C CG . LEU A 1 243 ? 47.547 29.741 128.180 1.00 2.00 ? 322 LEU N CG 1 ATOM 1907 C CD1 . LEU A 1 243 ? 46.737 29.390 126.986 1.00 2.00 ? 322 LEU N CD1 1 ATOM 1908 C CD2 . LEU A 1 243 ? 46.686 29.596 129.404 1.00 2.00 ? 322 LEU N CD2 1 ATOM 1909 N N . THR A 1 244 ? 51.157 27.112 129.748 1.00 8.92 ? 323 THR N N 1 ATOM 1910 C CA . THR A 1 244 ? 52.397 26.363 129.761 1.00 7.57 ? 323 THR N CA 1 ATOM 1911 C C . THR A 1 244 ? 52.313 24.975 129.111 1.00 7.36 ? 323 THR N C 1 ATOM 1912 O O . THR A 1 244 ? 53.342 24.314 129.011 1.00 9.58 ? 323 THR N O 1 ATOM 1913 C CB . THR A 1 244 ? 52.857 26.301 131.258 1.00 5.12 ? 323 THR N CB 1 ATOM 1914 O OG1 . THR A 1 244 ? 51.704 25.887 131.970 1.00 2.88 ? 323 THR N OG1 1 ATOM 1915 C CG2 . THR A 1 244 ? 53.291 27.618 131.886 1.00 4.72 ? 323 THR N CG2 1 ATOM 1916 N N . ASP A 1 245 ? 51.183 24.413 128.631 1.00 4.04 ? 324 ASP N N 1 ATOM 1917 C CA . ASP A 1 245 ? 51.195 23.091 128.020 1.00 2.02 ? 324 ASP N CA 1 ATOM 1918 C C . ASP A 1 245 ? 51.614 23.249 126.567 1.00 3.19 ? 324 ASP N C 1 ATOM 1919 O O . ASP A 1 245 ? 51.771 24.384 126.139 1.00 2.45 ? 324 ASP N O 1 ATOM 1920 C CB . ASP A 1 245 ? 49.824 22.447 128.076 1.00 2.16 ? 324 ASP N CB 1 ATOM 1921 C CG . ASP A 1 245 ? 49.817 20.914 127.958 1.00 3.53 ? 324 ASP N CG 1 ATOM 1922 O OD1 . ASP A 1 245 ? 50.899 20.330 127.917 1.00 2.15 ? 324 ASP N OD1 1 ATOM 1923 O OD2 . ASP A 1 245 ? 48.756 20.276 127.904 1.00 6.40 ? 324 ASP N OD2 1 ATOM 1924 N N . ASN A 1 246 ? 51.884 22.199 125.774 1.00 5.93 ? 325 ASN N N 1 ATOM 1925 C CA . ASN A 1 246 ? 52.218 22.376 124.380 1.00 6.42 ? 325 ASN N CA 1 ATOM 1926 C C . ASN A 1 246 ? 51.685 21.277 123.463 1.00 5.96 ? 325 ASN N C 1 ATOM 1927 O O . ASN A 1 246 ? 52.134 20.145 123.679 1.00 4.36 ? 325 ASN N O 1 ATOM 1928 C CB . ASN A 1 246 ? 53.721 22.453 124.238 1.00 7.86 ? 325 ASN N CB 1 ATOM 1929 C CG . ASN A 1 246 ? 54.162 22.498 122.773 1.00 8.38 ? 325 ASN N CG 1 ATOM 1930 O OD1 . ASN A 1 246 ? 54.211 21.472 122.089 1.00 12.57 ? 325 ASN N OD1 1 ATOM 1931 N ND2 . ASN A 1 246 ? 54.505 23.664 122.240 1.00 8.40 ? 325 ASN N ND2 1 ATOM 1932 N N . PRO A 1 247 ? 50.812 21.483 122.446 1.00 5.68 ? 326 PRO N N 1 ATOM 1933 C CA . PRO A 1 247 ? 50.287 22.771 121.962 1.00 5.42 ? 326 PRO N CA 1 ATOM 1934 C C . PRO A 1 247 ? 49.342 23.482 122.928 1.00 7.03 ? 326 PRO N C 1 ATOM 1935 O O . PRO A 1 247 ? 48.837 22.899 123.914 1.00 5.17 ? 326 PRO N O 1 ATOM 1936 C CB . PRO A 1 247 ? 49.578 22.474 120.676 1.00 2.60 ? 326 PRO N CB 1 ATOM 1937 C CG . PRO A 1 247 ? 49.886 21.023 120.481 1.00 4.30 ? 326 PRO N CG 1 ATOM 1938 C CD . PRO A 1 247 ? 50.012 20.432 121.863 1.00 4.96 ? 326 PRO N CD 1 ATOM 1939 N N . ARG A 1 248 ? 49.137 24.756 122.610 1.00 9.95 ? 327 ARG N N 1 ATOM 1940 C CA . ARG A 1 248 ? 48.294 25.611 123.390 1.00 13.91 ? 327 ARG N CA 1 ATOM 1941 C C . ARG A 1 248 ? 47.796 26.722 122.504 1.00 18.08 ? 327 ARG N C 1 ATOM 1942 O O . ARG A 1 248 ? 48.425 27.073 121.516 1.00 23.72 ? 327 ARG N O 1 ATOM 1943 C CB . ARG A 1 248 ? 49.033 26.241 124.549 1.00 10.71 ? 327 ARG N CB 1 ATOM 1944 C CG . ARG A 1 248 ? 50.282 27.014 124.158 1.00 11.32 ? 327 ARG N CG 1 ATOM 1945 C CD . ARG A 1 248 ? 50.715 27.985 125.238 1.00 9.17 ? 327 ARG N CD 1 ATOM 1946 N NE . ARG A 1 248 ? 51.998 28.608 124.938 1.00 11.32 ? 327 ARG N NE 1 ATOM 1947 C CZ . ARG A 1 248 ? 53.176 27.979 124.994 1.00 10.55 ? 327 ARG N CZ 1 ATOM 1948 N NH1 . ARG A 1 248 ? 53.323 26.681 125.197 1.00 10.81 ? 327 ARG N NH1 1 ATOM 1949 N NH2 . ARG A 1 248 ? 54.260 28.679 124.750 1.00 11.47 ? 327 ARG N NH2 1 ATOM 1950 N N . PRO A 1 249 ? 46.637 27.285 122.773 1.00 20.01 ? 328 PRO N N 1 ATOM 1951 C CA . PRO A 1 249 ? 46.291 28.600 122.322 1.00 18.75 ? 328 PRO N CA 1 ATOM 1952 C C . PRO A 1 249 ? 47.251 29.595 122.938 1.00 20.91 ? 328 PRO N C 1 ATOM 1953 O O . PRO A 1 249 ? 47.933 29.361 123.934 1.00 23.44 ? 328 PRO N O 1 ATOM 1954 C CB . PRO A 1 249 ? 44.861 28.707 122.765 1.00 18.31 ? 328 PRO N CB 1 ATOM 1955 C CG . PRO A 1 249 ? 44.762 27.783 123.949 1.00 20.05 ? 328 PRO N CG 1 ATOM 1956 C CD . PRO A 1 249 ? 45.536 26.624 123.438 1.00 20.62 ? 328 PRO N CD 1 ATOM 1957 N N . ASN A 1 250 ? 47.306 30.735 122.293 1.00 22.73 ? 329 ASN N N 1 ATOM 1958 C CA . ASN A 1 250 ? 48.114 31.864 122.738 1.00 23.86 ? 329 ASN N CA 1 ATOM 1959 C C . ASN A 1 250 ? 47.624 32.407 124.069 1.00 21.53 ? 329 ASN N C 1 ATOM 1960 O O . ASN A 1 250 ? 46.404 32.550 124.229 1.00 24.04 ? 329 ASN N O 1 ATOM 1961 C CB . ASN A 1 250 ? 48.062 33.015 121.716 1.00 29.09 ? 329 ASN N CB 1 ATOM 1962 C CG . ASN A 1 250 ? 48.736 32.708 120.389 1.00 32.76 ? 329 ASN N CG 1 ATOM 1963 O OD1 . ASN A 1 250 ? 49.941 32.915 120.208 1.00 37.83 ? 329 ASN N OD1 1 ATOM 1964 N ND2 . ASN A 1 250 ? 47.957 32.178 119.442 1.00 33.21 ? 329 ASN N ND2 1 ATOM 1965 N N . ASP A 1 251 ? 48.478 32.824 124.994 1.00 18.06 ? 330 ASP N N 1 ATOM 1966 C CA . ASP A 1 251 ? 48.012 33.214 126.345 1.00 16.11 ? 330 ASP N CA 1 ATOM 1967 C C . ASP A 1 251 ? 46.954 34.319 126.407 1.00 14.50 ? 330 ASP N C 1 ATOM 1968 O O . ASP A 1 251 ? 47.138 35.375 125.786 1.00 10.88 ? 330 ASP N O 1 ATOM 1969 C CB . ASP A 1 251 ? 49.120 33.720 127.233 1.00 15.06 ? 330 ASP N CB 1 ATOM 1970 C CG . ASP A 1 251 ? 50.466 33.062 127.027 1.00 13.10 ? 330 ASP N CG 1 ATOM 1971 O OD1 . ASP A 1 251 ? 50.504 31.849 126.780 1.00 15.58 ? 330 ASP N OD1 1 ATOM 1972 O OD2 . ASP A 1 251 ? 51.469 33.790 127.113 1.00 9.26 ? 330 ASP N OD2 1 ATOM 1973 N N . PRO A 1 252 ? 45.822 34.122 127.107 1.00 13.28 ? 331 PRO N N 1 ATOM 1974 C CA . PRO A 1 252 ? 44.814 35.136 127.357 1.00 13.07 ? 331 PRO N CA 1 ATOM 1975 C C . PRO A 1 252 ? 45.348 36.269 128.257 1.00 15.82 ? 331 PRO N C 1 ATOM 1976 O O . PRO A 1 252 ? 46.554 36.393 128.505 1.00 16.86 ? 331 PRO N O 1 ATOM 1977 C CB . PRO A 1 252 ? 43.711 34.310 127.952 1.00 11.58 ? 331 PRO N CB 1 ATOM 1978 C CG . PRO A 1 252 ? 44.429 33.336 128.835 1.00 11.35 ? 331 PRO N CG 1 ATOM 1979 C CD . PRO A 1 252 ? 45.515 32.929 127.903 1.00 12.19 ? 331 PRO N CD 1 ATOM 1980 N N . THR A 1 253 ? 44.455 37.128 128.741 1.00 17.58 ? 332 THR N N 1 ATOM 1981 C CA . THR A 1 253 ? 44.841 38.121 129.713 1.00 18.86 ? 332 THR N CA 1 ATOM 1982 C C . THR A 1 253 ? 44.346 37.700 131.096 1.00 20.08 ? 332 THR N C 1 ATOM 1983 O O . THR A 1 253 ? 44.781 38.250 132.111 1.00 21.88 ? 332 THR N O 1 ATOM 1984 C CB . THR A 1 253 ? 44.222 39.394 129.333 1.00 19.15 ? 332 THR N CB 1 ATOM 1985 O OG1 . THR A 1 253 ? 42.855 39.052 129.247 1.00 21.70 ? 332 THR N OG1 1 ATOM 1986 C CG2 . THR A 1 253 ? 44.679 39.972 128.020 1.00 20.19 ? 332 THR N CG2 1 ATOM 1987 N N . VAL A 1 254 ? 43.335 36.816 131.113 1.00 21.31 ? 333 VAL N N 1 ATOM 1988 C CA . VAL A 1 254 ? 42.741 36.229 132.303 1.00 20.68 ? 333 VAL N CA 1 ATOM 1989 C C . VAL A 1 254 ? 42.817 34.754 132.024 1.00 19.76 ? 333 VAL N C 1 ATOM 1990 O O . VAL A 1 254 ? 42.458 34.364 130.923 1.00 20.39 ? 333 VAL N O 1 ATOM 1991 C CB . VAL A 1 254 ? 41.293 36.602 132.451 1.00 22.58 ? 333 VAL N CB 1 ATOM 1992 C CG1 . VAL A 1 254 ? 40.588 35.823 133.514 1.00 26.36 ? 333 VAL N CG1 1 ATOM 1993 C CG2 . VAL A 1 254 ? 41.259 38.026 132.851 1.00 23.38 ? 333 VAL N CG2 1 ATOM 1994 N N . GLY A 1 255 ? 43.254 33.944 132.976 1.00 17.56 ? 335 GLY N N 1 ATOM 1995 C CA . GLY A 1 255 ? 43.471 32.514 132.763 1.00 15.22 ? 335 GLY N CA 1 ATOM 1996 C C . GLY A 1 255 ? 42.376 31.657 133.366 1.00 15.02 ? 335 GLY N C 1 ATOM 1997 O O . GLY A 1 255 ? 41.265 32.167 133.380 1.00 14.64 ? 335 GLY N O 1 ATOM 1998 N N . LYS A 1 256 ? 42.572 30.430 133.905 1.00 15.84 ? 336 LYS N N 1 ATOM 1999 C CA . LYS A 1 256 ? 41.479 29.619 134.467 1.00 16.61 ? 336 LYS N CA 1 ATOM 2000 C C . LYS A 1 256 ? 41.944 28.657 135.552 1.00 17.81 ? 336 LYS N C 1 ATOM 2001 O O . LYS A 1 256 ? 42.790 27.804 135.300 1.00 20.48 ? 336 LYS N O 1 ATOM 2002 C CB . LYS A 1 256 ? 40.761 28.760 133.422 1.00 15.91 ? 336 LYS N CB 1 ATOM 2003 C CG . LYS A 1 256 ? 39.699 29.483 132.616 1.00 17.53 ? 336 LYS N CG 1 ATOM 2004 C CD . LYS A 1 256 ? 38.903 28.472 131.799 1.00 18.55 ? 336 LYS N CD 1 ATOM 2005 C CE . LYS A 1 256 ? 37.695 29.133 131.149 1.00 20.47 ? 336 LYS N CE 1 ATOM 2006 N NZ . LYS A 1 256 ? 36.724 28.152 130.685 1.00 19.55 ? 336 LYS N NZ 1 ATOM 2007 N N . CYS A 1 257 ? 41.422 28.746 136.779 1.00 15.99 ? 337 CYS N N 1 ATOM 2008 C CA . CYS A 1 257 ? 41.886 27.875 137.835 1.00 14.21 ? 337 CYS N CA 1 ATOM 2009 C C . CYS A 1 257 ? 41.026 26.678 138.119 1.00 16.05 ? 337 CYS N C 1 ATOM 2010 O O . CYS A 1 257 ? 41.518 25.783 138.792 1.00 14.41 ? 337 CYS N O 1 ATOM 2011 C CB . CYS A 1 257 ? 41.978 28.538 139.177 1.00 14.46 ? 337 CYS N CB 1 ATOM 2012 S SG . CYS A 1 257 ? 42.206 30.347 139.157 1.00 11.10 ? 337 CYS N SG 1 ATOM 2013 N N . ASN A 1 258 ? 39.774 26.536 137.684 1.00 20.30 ? 338 ASN N N 1 ATOM 2014 C CA . ASN A 1 258 ? 39.002 25.383 138.120 1.00 23.31 ? 338 ASN N CA 1 ATOM 2015 C C . ASN A 1 258 ? 38.469 24.556 136.992 1.00 24.13 ? 338 ASN N C 1 ATOM 2016 O O . ASN A 1 258 ? 37.636 23.676 137.188 1.00 27.71 ? 338 ASN N O 1 ATOM 2017 C CB . ASN A 1 258 ? 37.852 25.832 139.030 1.00 23.41 ? 338 ASN N CB 1 ATOM 2018 C CG . ASN A 1 258 ? 38.291 25.967 140.490 1.00 25.51 ? 338 ASN N CG 1 ATOM 2019 O OD1 . ASN A 1 258 ? 39.125 25.206 140.995 1.00 23.25 ? 338 ASN N OD1 1 ATOM 2020 N ND2 . ASN A 1 258 ? 37.795 26.949 141.237 1.00 28.81 ? 338 ASN N ND2 1 ATOM 2021 N N . ASP A 1 259 ? 38.937 24.855 135.779 1.00 24.87 ? 339 ASP N N 1 ATOM 2022 C CA . ASP A 1 259 ? 38.589 24.109 134.573 1.00 23.49 ? 339 ASP N CA 1 ATOM 2023 C C . ASP A 1 259 ? 39.776 24.189 133.605 1.00 22.08 ? 339 ASP N C 1 ATOM 2024 O O . ASP A 1 259 ? 40.600 25.101 133.730 1.00 23.84 ? 339 ASP N O 1 ATOM 2025 C CB . ASP A 1 259 ? 37.399 24.689 133.833 1.00 26.85 ? 339 ASP N CB 1 ATOM 2026 C CG . ASP A 1 259 ? 36.185 24.994 134.666 1.00 31.03 ? 339 ASP N CG 1 ATOM 2027 O OD1 . ASP A 1 259 ? 36.181 26.050 135.296 1.00 34.37 ? 339 ASP N OD1 1 ATOM 2028 O OD2 . ASP A 1 259 ? 35.278 24.172 134.691 1.00 33.72 ? 339 ASP N OD2 1 ATOM 2029 N N . PRO A 1 260 ? 39.950 23.271 132.664 1.00 19.31 ? 340 PRO N N 1 ATOM 2030 C CA . PRO A 1 260 ? 40.841 23.407 131.555 1.00 17.92 ? 340 PRO N CA 1 ATOM 2031 C C . PRO A 1 260 ? 40.653 24.696 130.797 1.00 19.46 ? 340 PRO N C 1 ATOM 2032 O O . PRO A 1 260 ? 39.527 25.192 130.633 1.00 19.92 ? 340 PRO N O 1 ATOM 2033 C CB . PRO A 1 260 ? 40.580 22.191 130.715 1.00 15.50 ? 340 PRO N CB 1 ATOM 2034 C CG . PRO A 1 260 ? 39.292 21.632 131.242 1.00 15.69 ? 340 PRO N CG 1 ATOM 2035 C CD . PRO A 1 260 ? 39.465 21.915 132.702 1.00 16.69 ? 340 PRO N CD 1 ATOM 2036 N N . TYR A 1 261 ? 41.759 25.236 130.295 1.00 21.98 ? 341 TYR N N 1 ATOM 2037 C CA . TYR A 1 261 ? 41.675 26.449 129.546 1.00 23.37 ? 341 TYR N CA 1 ATOM 2038 C C . TYR A 1 261 ? 41.558 25.934 128.142 1.00 24.14 ? 341 TYR N C 1 ATOM 2039 O O . TYR A 1 261 ? 42.437 25.218 127.644 1.00 24.10 ? 341 TYR N O 1 ATOM 2040 C CB . TYR A 1 261 ? 42.906 27.313 129.624 1.00 24.68 ? 341 TYR N CB 1 ATOM 2041 C CG . TYR A 1 261 ? 42.574 28.633 128.957 1.00 24.45 ? 341 TYR N CG 1 ATOM 2042 C CD1 . TYR A 1 261 ? 42.008 29.632 129.702 1.00 24.43 ? 341 TYR N CD1 1 ATOM 2043 C CD2 . TYR A 1 261 ? 42.781 28.790 127.605 1.00 24.35 ? 341 TYR N CD2 1 ATOM 2044 C CE1 . TYR A 1 261 ? 41.629 30.796 129.089 1.00 24.87 ? 341 TYR N CE1 1 ATOM 2045 C CE2 . TYR A 1 261 ? 42.401 29.951 126.994 1.00 25.01 ? 341 TYR N CE2 1 ATOM 2046 C CZ . TYR A 1 261 ? 41.829 30.937 127.743 1.00 24.18 ? 341 TYR N CZ 1 ATOM 2047 O OH . TYR A 1 261 ? 41.411 32.074 127.114 1.00 26.49 ? 341 TYR N OH 1 ATOM 2048 N N . PRO A 1 262 ? 40.444 26.320 127.538 1.00 24.18 ? 342 PRO N N 1 ATOM 2049 C CA . PRO A 1 262 ? 39.981 25.777 126.277 1.00 23.76 ? 342 PRO N CA 1 ATOM 2050 C C . PRO A 1 262 ? 40.824 26.141 125.063 1.00 23.50 ? 342 PRO N C 1 ATOM 2051 O O . PRO A 1 262 ? 41.156 27.312 124.829 1.00 21.61 ? 342 PRO N O 1 ATOM 2052 C CB . PRO A 1 262 ? 38.548 26.275 126.191 1.00 22.83 ? 342 PRO N CB 1 ATOM 2053 C CG . PRO A 1 262 ? 38.599 27.589 126.938 1.00 22.06 ? 342 PRO N CG 1 ATOM 2054 C CD . PRO A 1 262 ? 39.428 27.193 128.125 1.00 23.05 ? 342 PRO N CD 1 ATOM 2055 N N . GLY A 1 263 ? 41.182 25.150 124.266 1.00 24.18 ? 343 GLY N N 1 ATOM 2056 C CA . GLY A 1 263 ? 41.868 25.460 123.029 1.00 25.91 ? 343 GLY N CA 1 ATOM 2057 C C . GLY A 1 263 ? 42.528 24.239 122.444 1.00 28.46 ? 343 GLY N C 1 ATOM 2058 O O . GLY A 1 263 ? 42.038 23.786 121.399 1.00 31.67 ? 343 GLY N O 1 ATOM 2059 N N . ASN A 1 264 ? 43.570 23.645 123.071 1.00 29.70 ? 344 ASN N N 1 ATOM 2060 C CA . ASN A 1 264 ? 44.175 22.536 122.368 1.00 29.46 ? 344 ASN N CA 1 ATOM 2061 C C . ASN A 1 264 ? 43.998 21.256 123.102 1.00 31.82 ? 344 ASN N C 1 ATOM 2062 O O . ASN A 1 264 ? 44.681 20.933 124.108 1.00 35.77 ? 344 ASN N O 1 ATOM 2063 C CB . ASN A 1 264 ? 45.667 22.702 122.119 1.00 27.82 ? 344 ASN N CB 1 ATOM 2064 C CG . ASN A 1 264 ? 46.138 21.479 121.349 1.00 27.76 ? 344 ASN N CG 1 ATOM 2065 O OD1 . ASN A 1 264 ? 46.684 20.550 121.946 1.00 28.15 ? 344 ASN N OD1 1 ATOM 2066 N ND2 . ASN A 1 264 ? 45.863 21.388 120.054 1.00 28.21 ? 344 ASN N ND2 1 ATOM 2067 N N . ASN A 1 265 ? 43.148 20.506 122.391 1.00 32.91 ? 345 ASN N N 1 ATOM 2068 C CA . ASN A 1 265 ? 42.694 19.244 122.944 1.00 34.40 ? 345 ASN N CA 1 ATOM 2069 C C . ASN A 1 265 ? 43.188 17.977 122.277 1.00 31.20 ? 345 ASN N C 1 ATOM 2070 O O . ASN A 1 265 ? 43.685 17.966 121.151 1.00 32.52 ? 345 ASN N O 1 ATOM 2071 C CB . ASN A 1 265 ? 41.169 19.200 123.003 1.00 40.71 ? 345 ASN N CB 1 ATOM 2072 C CG . ASN A 1 265 ? 40.427 19.281 121.701 1.00 47.10 ? 345 ASN N CG 1 ATOM 2073 O OD1 . ASN A 1 265 ? 39.202 19.219 121.734 1.00 50.86 ? 345 ASN N OD1 1 ATOM 2074 N ND2 . ASN A 1 265 ? 41.057 19.449 120.536 1.00 49.25 ? 345 ASN N ND2 1 ATOM 2075 N N . ASN A 1 266 ? 43.134 16.964 123.131 1.00 28.70 ? 346 ASN N N 1 ATOM 2076 C CA . ASN A 1 266 ? 43.677 15.645 122.932 1.00 26.98 ? 346 ASN N CA 1 ATOM 2077 C C . ASN A 1 266 ? 45.196 15.592 122.845 1.00 26.07 ? 346 ASN N C 1 ATOM 2078 O O . ASN A 1 266 ? 45.745 14.596 122.382 1.00 28.07 ? 346 ASN N O 1 ATOM 2079 C CB . ASN A 1 266 ? 43.063 15.005 121.693 1.00 26.31 ? 346 ASN N CB 1 ATOM 2080 C CG . ASN A 1 266 ? 41.636 14.601 121.995 1.00 27.24 ? 346 ASN N CG 1 ATOM 2081 O OD1 . ASN A 1 266 ? 40.698 15.340 121.757 1.00 28.40 ? 346 ASN N OD1 1 ATOM 2082 N ND2 . ASN A 1 266 ? 41.363 13.464 122.598 1.00 26.71 ? 346 ASN N ND2 1 ATOM 2083 N N . ASN A 1 267 ? 45.922 16.543 123.473 1.00 22.77 ? 347 ASN N N 1 ATOM 2084 C CA . ASN A 1 267 ? 47.374 16.677 123.345 1.00 18.29 ? 347 ASN N CA 1 ATOM 2085 C C . ASN A 1 267 ? 47.951 17.543 124.461 1.00 16.49 ? 347 ASN N C 1 ATOM 2086 O O . ASN A 1 267 ? 47.254 18.368 125.131 1.00 18.93 ? 347 ASN N O 1 ATOM 2087 C CB . ASN A 1 267 ? 47.588 17.266 121.944 1.00 18.24 ? 347 ASN N CB 1 ATOM 2088 C CG . ASN A 1 267 ? 48.910 17.259 121.181 1.00 19.60 ? 347 ASN N CG 1 ATOM 2089 O OD1 . ASN A 1 267 ? 49.963 16.763 121.545 1.00 24.09 ? 347 ASN N OD1 1 ATOM 2090 N ND2 . ASN A 1 267 ? 48.877 17.884 120.016 1.00 17.02 ? 347 ASN N ND2 1 ATOM 2091 N N . GLY A 1 268 ? 49.252 17.342 124.658 1.00 13.72 ? 348 GLY N N 1 ATOM 2092 C CA . GLY A 1 268 ? 50.119 18.033 125.622 1.00 9.86 ? 348 GLY N CA 1 ATOM 2093 C C . GLY A 1 268 ? 51.586 17.551 125.616 1.00 10.85 ? 348 GLY N C 1 ATOM 2094 O O . GLY A 1 268 ? 51.976 16.779 124.748 1.00 15.26 ? 348 GLY N O 1 ATOM 2095 N N . VAL A 1 269 ? 52.434 17.963 126.566 1.00 9.85 ? 349 VAL N N 1 ATOM 2096 C CA . VAL A 1 269 ? 53.806 17.452 126.704 1.00 5.39 ? 349 VAL N CA 1 ATOM 2097 C C . VAL A 1 269 ? 54.097 17.584 128.185 1.00 4.67 ? 349 VAL N C 1 ATOM 2098 O O . VAL A 1 269 ? 53.667 18.552 128.795 1.00 4.64 ? 349 VAL N O 1 ATOM 2099 C CB . VAL A 1 269 ? 54.885 18.258 125.873 1.00 3.77 ? 349 VAL N CB 1 ATOM 2100 C CG1 . VAL A 1 269 ? 55.115 19.666 126.343 1.00 2.09 ? 349 VAL N CG1 1 ATOM 2101 C CG2 . VAL A 1 269 ? 56.192 17.530 126.012 1.00 2.25 ? 349 VAL N CG2 1 ATOM 2102 N N . LYS A 1 270 ? 54.709 16.597 128.808 1.00 3.62 ? 350 LYS N N 1 ATOM 2103 C CA . LYS A 1 270 ? 54.970 16.652 130.240 1.00 2.09 ? 350 LYS N CA 1 ATOM 2104 C C . LYS A 1 270 ? 55.710 17.905 130.655 1.00 2.97 ? 350 LYS N C 1 ATOM 2105 O O . LYS A 1 270 ? 56.568 18.336 129.871 1.00 3.37 ? 350 LYS N O 1 ATOM 2106 C CB . LYS A 1 270 ? 55.772 15.437 130.640 1.00 2.06 ? 350 LYS N CB 1 ATOM 2107 C CG . LYS A 1 270 ? 56.301 15.463 132.046 1.00 5.12 ? 350 LYS N CG 1 ATOM 2108 C CD . LYS A 1 270 ? 57.112 14.243 132.350 1.00 4.37 ? 350 LYS N CD 1 ATOM 2109 C CE . LYS A 1 270 ? 57.566 14.458 133.748 1.00 9.10 ? 350 LYS N CE 1 ATOM 2110 N NZ . LYS A 1 270 ? 56.508 14.461 134.751 1.00 9.78 ? 350 LYS N NZ 1 ATOM 2111 N N . GLY A 1 271 ? 55.423 18.465 131.852 1.00 3.59 ? 351 GLY N N 1 ATOM 2112 C CA . GLY A 1 271 ? 56.059 19.707 132.292 1.00 2.39 ? 351 GLY N CA 1 ATOM 2113 C C . GLY A 1 271 ? 56.096 19.807 133.797 1.00 3.47 ? 351 GLY N C 1 ATOM 2114 O O . GLY A 1 271 ? 55.604 18.905 134.482 1.00 8.83 ? 351 GLY N O 1 ATOM 2115 N N . PHE A 1 272 ? 56.668 20.920 134.268 1.00 2.10 ? 352 PHE N N 1 ATOM 2116 C CA . PHE A 1 272 ? 56.758 21.198 135.685 1.00 2.51 ? 352 PHE N CA 1 ATOM 2117 C C . PHE A 1 272 ? 56.547 22.674 135.999 1.00 3.13 ? 352 PHE N C 1 ATOM 2118 O O . PHE A 1 272 ? 56.238 23.462 135.105 1.00 2.03 ? 352 PHE N O 1 ATOM 2119 C CB . PHE A 1 272 ? 58.126 20.749 136.227 1.00 2.18 ? 352 PHE N CB 1 ATOM 2120 C CG . PHE A 1 272 ? 59.257 21.668 135.857 1.00 3.02 ? 352 PHE N CG 1 ATOM 2121 C CD1 . PHE A 1 272 ? 59.793 21.590 134.604 1.00 3.38 ? 352 PHE N CD1 1 ATOM 2122 C CD2 . PHE A 1 272 ? 59.669 22.610 136.745 1.00 3.01 ? 352 PHE N CD2 1 ATOM 2123 C CE1 . PHE A 1 272 ? 60.732 22.506 134.214 1.00 2.18 ? 352 PHE N CE1 1 ATOM 2124 C CE2 . PHE A 1 272 ? 60.598 23.530 136.357 1.00 2.75 ? 352 PHE N CE2 1 ATOM 2125 C CZ . PHE A 1 272 ? 61.138 23.480 135.097 1.00 3.29 ? 352 PHE N CZ 1 ATOM 2126 N N . SER A 1 273 ? 56.720 23.064 137.273 1.00 2.87 ? 353 SER N N 1 ATOM 2127 C CA . SER A 1 273 ? 56.613 24.439 137.743 1.00 3.85 ? 353 SER N CA 1 ATOM 2128 C C . SER A 1 273 ? 57.029 24.430 139.203 1.00 6.04 ? 353 SER N C 1 ATOM 2129 O O . SER A 1 273 ? 56.875 23.384 139.859 1.00 8.07 ? 353 SER N O 1 ATOM 2130 C CB . SER A 1 273 ? 55.168 24.930 137.627 1.00 2.12 ? 353 SER N CB 1 ATOM 2131 O OG . SER A 1 273 ? 54.239 24.167 138.379 1.00 2.08 ? 353 SER N OG 1 ATOM 2132 N N . TYR A 1 274 ? 57.575 25.521 139.753 1.00 5.65 ? 354 TYR N N 1 ATOM 2133 C CA . TYR A 1 274 ? 57.816 25.573 141.176 1.00 3.08 ? 354 TYR N CA 1 ATOM 2134 C C . TYR A 1 274 ? 56.815 26.616 141.566 1.00 2.00 ? 354 TYR N C 1 ATOM 2135 O O . TYR A 1 274 ? 56.792 27.717 141.030 1.00 2.55 ? 354 TYR N O 1 ATOM 2136 C CB . TYR A 1 274 ? 59.245 25.982 141.455 1.00 2.12 ? 354 TYR N CB 1 ATOM 2137 C CG . TYR A 1 274 ? 60.120 24.734 141.384 1.00 2.42 ? 354 TYR N CG 1 ATOM 2138 C CD1 . TYR A 1 274 ? 60.293 23.943 142.513 1.00 2.00 ? 354 TYR N CD1 1 ATOM 2139 C CD2 . TYR A 1 274 ? 60.702 24.330 140.203 1.00 2.28 ? 354 TYR N CD2 1 ATOM 2140 C CE1 . TYR A 1 274 ? 61.031 22.771 142.517 1.00 2.00 ? 354 TYR N CE1 1 ATOM 2141 C CE2 . TYR A 1 274 ? 61.444 23.154 140.206 1.00 2.65 ? 354 TYR N CE2 1 ATOM 2142 C CZ . TYR A 1 274 ? 61.604 22.378 141.344 1.00 2.04 ? 354 TYR N CZ 1 ATOM 2143 O OH . TYR A 1 274 ? 62.342 21.214 141.332 1.00 4.60 ? 354 TYR N OH 1 ATOM 2144 N N . LEU A 1 275 ? 55.902 26.173 142.433 1.00 2.00 ? 355 LEU N N 1 ATOM 2145 C CA . LEU A 1 275 ? 54.760 26.961 142.900 1.00 2.73 ? 355 LEU N CA 1 ATOM 2146 C C . LEU A 1 275 ? 54.962 27.454 144.329 1.00 2.83 ? 355 LEU N C 1 ATOM 2147 O O . LEU A 1 275 ? 54.843 26.708 145.303 1.00 4.13 ? 355 LEU N O 1 ATOM 2148 C CB . LEU A 1 275 ? 53.494 26.112 142.811 1.00 2.00 ? 355 LEU N CB 1 ATOM 2149 C CG . LEU A 1 275 ? 53.036 25.825 141.397 1.00 2.00 ? 355 LEU N CG 1 ATOM 2150 C CD1 . LEU A 1 275 ? 51.853 24.892 141.401 1.00 2.31 ? 355 LEU N CD1 1 ATOM 2151 C CD2 . LEU A 1 275 ? 52.696 27.120 140.754 1.00 2.00 ? 355 LEU N CD2 1 ATOM 2152 N N . ASP A 1 276 ? 55.322 28.724 144.478 1.00 3.50 ? 356 ASP N N 1 ATOM 2153 C CA . ASP A 1 276 ? 55.641 29.244 145.779 1.00 6.67 ? 356 ASP N CA 1 ATOM 2154 C C . ASP A 1 276 ? 55.383 30.734 145.959 1.00 8.01 ? 356 ASP N C 1 ATOM 2155 O O . ASP A 1 276 ? 56.243 31.493 146.406 1.00 11.10 ? 356 ASP N O 1 ATOM 2156 C CB . ASP A 1 276 ? 57.091 28.873 145.999 1.00 9.98 ? 356 ASP N CB 1 ATOM 2157 C CG . ASP A 1 276 ? 57.651 29.094 147.385 1.00 10.57 ? 356 ASP N CG 1 ATOM 2158 O OD1 . ASP A 1 276 ? 57.014 28.678 148.364 1.00 13.22 ? 356 ASP N OD1 1 ATOM 2159 O OD2 . ASP A 1 276 ? 58.749 29.645 147.452 1.00 9.12 ? 356 ASP N OD2 1 ATOM 2160 N N . GLY A 1 277 ? 54.203 31.238 145.615 1.00 7.64 ? 357 GLY N N 1 ATOM 2161 C CA . GLY A 1 277 ? 53.840 32.631 145.837 1.00 7.81 ? 357 GLY N CA 1 ATOM 2162 C C . GLY A 1 277 ? 54.661 33.557 144.992 1.00 7.65 ? 357 GLY N C 1 ATOM 2163 O O . GLY A 1 277 ? 54.740 33.394 143.765 1.00 9.47 ? 357 GLY N O 1 ATOM 2164 N N . GLY A 1 278 ? 55.356 34.477 145.636 1.00 7.01 ? 358 GLY N N 1 ATOM 2165 C CA . GLY A 1 278 ? 56.164 35.456 144.918 1.00 8.92 ? 358 GLY N CA 1 ATOM 2166 C C . GLY A 1 278 ? 57.225 34.794 144.067 1.00 9.24 ? 358 GLY N C 1 ATOM 2167 O O . GLY A 1 278 ? 57.558 35.249 142.972 1.00 12.55 ? 358 GLY N O 1 ATOM 2168 N N . ASN A 1 279 ? 57.638 33.639 144.570 1.00 7.85 ? 359 ASN N N 1 ATOM 2169 C CA . ASN A 1 279 ? 58.722 32.872 144.033 1.00 9.09 ? 359 ASN N CA 1 ATOM 2170 C C . ASN A 1 279 ? 58.219 31.695 143.230 1.00 8.55 ? 359 ASN N C 1 ATOM 2171 O O . ASN A 1 279 ? 58.551 30.524 143.413 1.00 11.93 ? 359 ASN N O 1 ATOM 2172 C CB . ASN A 1 279 ? 59.543 32.475 145.219 1.00 11.57 ? 359 ASN N CB 1 ATOM 2173 C CG . ASN A 1 279 ? 60.902 31.908 144.895 1.00 13.42 ? 359 ASN N CG 1 ATOM 2174 O OD1 . ASN A 1 279 ? 61.770 32.478 144.221 1.00 15.38 ? 359 ASN N OD1 1 ATOM 2175 N ND2 . ASN A 1 279 ? 61.049 30.742 145.464 1.00 13.66 ? 359 ASN N ND2 1 ATOM 2176 N N . THR A 1 280 ? 57.325 31.992 142.326 1.00 4.31 ? 360 THR N N 1 ATOM 2177 C CA . THR A 1 280 ? 56.822 30.982 141.442 1.00 5.21 ? 360 THR N CA 1 ATOM 2178 C C . THR A 1 280 ? 57.530 31.187 140.116 1.00 6.55 ? 360 THR N C 1 ATOM 2179 O O . THR A 1 280 ? 57.660 32.314 139.645 1.00 7.70 ? 360 THR N O 1 ATOM 2180 C CB . THR A 1 280 ? 55.315 31.174 141.359 1.00 5.71 ? 360 THR N CB 1 ATOM 2181 O OG1 . THR A 1 280 ? 54.834 31.014 142.704 1.00 4.79 ? 360 THR N OG1 1 ATOM 2182 C CG2 . THR A 1 280 ? 54.631 30.214 140.411 1.00 4.39 ? 360 THR N CG2 1 ATOM 2183 N N . TRP A 1 281 ? 58.017 30.078 139.563 1.00 6.58 ? 361 TRP N N 1 ATOM 2184 C CA . TRP A 1 281 ? 58.642 29.973 138.256 1.00 3.60 ? 361 TRP N CA 1 ATOM 2185 C C . TRP A 1 281 ? 57.915 28.866 137.497 1.00 5.20 ? 361 TRP N C 1 ATOM 2186 O O . TRP A 1 281 ? 57.607 27.801 138.032 1.00 6.10 ? 361 TRP N O 1 ATOM 2187 C CB . TRP A 1 281 ? 60.150 29.630 138.390 1.00 5.45 ? 361 TRP N CB 1 ATOM 2188 C CG . TRP A 1 281 ? 61.036 30.847 138.680 1.00 4.20 ? 361 TRP N CG 1 ATOM 2189 C CD1 . TRP A 1 281 ? 61.116 31.419 139.932 1.00 3.77 ? 361 TRP N CD1 1 ATOM 2190 C CD2 . TRP A 1 281 ? 61.771 31.533 137.753 1.00 2.48 ? 361 TRP N CD2 1 ATOM 2191 N NE1 . TRP A 1 281 ? 61.876 32.464 139.791 1.00 3.38 ? 361 TRP N NE1 1 ATOM 2192 C CE2 . TRP A 1 281 ? 62.290 32.576 138.512 1.00 3.42 ? 361 TRP N CE2 1 ATOM 2193 C CE3 . TRP A 1 281 ? 62.067 31.445 136.424 1.00 2.90 ? 361 TRP N CE3 1 ATOM 2194 C CZ2 . TRP A 1 281 ? 63.122 33.538 137.938 1.00 2.00 ? 361 TRP N CZ2 1 ATOM 2195 C CZ3 . TRP A 1 281 ? 62.891 32.388 135.852 1.00 2.16 ? 361 TRP N CZ3 1 ATOM 2196 C CH2 . TRP A 1 281 ? 63.410 33.424 136.589 1.00 2.00 ? 361 TRP N CH2 1 ATOM 2197 N N . LEU A 1 282 ? 57.557 29.127 136.245 1.00 5.78 ? 362 LEU N N 1 ATOM 2198 C CA . LEU A 1 282 ? 56.857 28.181 135.380 1.00 5.44 ? 362 LEU N CA 1 ATOM 2199 C C . LEU A 1 282 ? 57.790 27.977 134.184 1.00 5.14 ? 362 LEU N C 1 ATOM 2200 O O . LEU A 1 282 ? 58.530 28.879 133.717 1.00 3.01 ? 362 LEU N O 1 ATOM 2201 C CB . LEU A 1 282 ? 55.536 28.708 134.796 1.00 4.57 ? 362 LEU N CB 1 ATOM 2202 C CG . LEU A 1 282 ? 54.613 29.654 135.520 1.00 4.84 ? 362 LEU N CG 1 ATOM 2203 C CD1 . LEU A 1 282 ? 53.207 29.425 135.029 1.00 2.00 ? 362 LEU N CD1 1 ATOM 2204 C CD2 . LEU A 1 282 ? 54.596 29.373 137.007 1.00 4.04 ? 362 LEU N CD2 1 ATOM 2205 N N . GLY A 1 283 ? 57.749 26.746 133.703 1.00 4.07 ? 363 GLY N N 1 ATOM 2206 C CA . GLY A 1 283 ? 58.560 26.447 132.553 1.00 5.21 ? 363 GLY N CA 1 ATOM 2207 C C . GLY A 1 283 ? 57.573 26.202 131.448 1.00 3.24 ? 363 GLY N C 1 ATOM 2208 O O . GLY A 1 283 ? 56.463 25.740 131.789 1.00 3.39 ? 363 GLY N O 1 ATOM 2209 N N . ARG A 1 284 ? 57.957 26.570 130.199 1.00 2.60 ? 364 ARG N N 1 ATOM 2210 C CA . ARG A 1 284 ? 57.176 26.295 128.989 1.00 3.59 ? 364 ARG N CA 1 ATOM 2211 C C . ARG A 1 284 ? 58.031 26.246 127.711 1.00 3.65 ? 364 ARG N C 1 ATOM 2212 O O . ARG A 1 284 ? 59.126 26.840 127.616 1.00 5.42 ? 364 ARG N O 1 ATOM 2213 C CB . ARG A 1 284 ? 56.053 27.363 128.840 1.00 3.31 ? 364 ARG N CB 1 ATOM 2214 C CG . ARG A 1 284 ? 56.440 28.819 129.011 1.00 2.01 ? 364 ARG N CG 1 ATOM 2215 C CD . ARG A 1 284 ? 56.119 29.608 127.779 1.00 2.14 ? 364 ARG N CD 1 ATOM 2216 N NE . ARG A 1 284 ? 54.733 29.996 127.730 1.00 2.39 ? 364 ARG N NE 1 ATOM 2217 C CZ . ARG A 1 284 ? 54.379 31.290 127.764 1.00 2.13 ? 364 ARG N CZ 1 ATOM 2218 N NH1 . ARG A 1 284 ? 55.230 32.305 127.795 1.00 4.44 ? 364 ARG N NH1 1 ATOM 2219 N NH2 . ARG A 1 284 ? 53.101 31.616 127.762 1.00 2.01 ? 364 ARG N NH2 1 ATOM 2220 N N . THR A 1 285 ? 57.582 25.512 126.687 1.00 4.06 ? 365 THR N N 1 ATOM 2221 C CA . THR A 1 285 ? 58.229 25.518 125.379 1.00 4.63 ? 365 THR N CA 1 ATOM 2222 C C . THR A 1 285 ? 57.949 26.907 124.796 1.00 5.74 ? 365 THR N C 1 ATOM 2223 O O . THR A 1 285 ? 56.998 27.575 125.200 1.00 8.90 ? 365 THR N O 1 ATOM 2224 C CB . THR A 1 285 ? 57.636 24.455 124.404 1.00 4.82 ? 365 THR N CB 1 ATOM 2225 O OG1 . THR A 1 285 ? 56.312 24.876 124.141 1.00 2.00 ? 365 THR N OG1 1 ATOM 2226 C CG2 . THR A 1 285 ? 57.662 23.027 124.929 1.00 2.01 ? 365 THR N CG2 1 ATOM 2227 N N . ILE A 1 286 ? 58.660 27.385 123.807 1.00 6.31 ? 366 ILE N N 1 ATOM 2228 C CA . ILE A 1 286 ? 58.380 28.712 123.340 1.00 5.65 ? 366 ILE N CA 1 ATOM 2229 C C . ILE A 1 286 ? 57.312 28.539 122.268 1.00 8.90 ? 366 ILE N C 1 ATOM 2230 O O . ILE A 1 286 ? 56.322 29.284 122.263 1.00 11.77 ? 366 ILE N O 1 ATOM 2231 C CB . ILE A 1 286 ? 59.691 29.322 122.830 1.00 4.61 ? 366 ILE N CB 1 ATOM 2232 C CG1 . ILE A 1 286 ? 60.675 29.419 123.989 1.00 2.05 ? 366 ILE N CG1 1 ATOM 2233 C CG2 . ILE A 1 286 ? 59.443 30.716 122.271 1.00 5.68 ? 366 ILE N CG2 1 ATOM 2234 C CD1 . ILE A 1 286 ? 62.063 30.071 123.746 1.00 2.09 ? 366 ILE N CD1 1 ATOM 2235 N N . SER A 1 287 ? 57.430 27.556 121.381 1.00 9.03 ? 367 SER N N 1 ATOM 2236 C CA . SER A 1 287 ? 56.466 27.387 120.317 1.00 9.27 ? 367 SER N CA 1 ATOM 2237 C C . SER A 1 287 ? 55.069 27.081 120.830 1.00 8.41 ? 367 SER N C 1 ATOM 2238 O O . SER A 1 287 ? 54.889 26.221 121.684 1.00 11.17 ? 367 SER N O 1 ATOM 2239 C CB . SER A 1 287 ? 56.954 26.278 119.414 1.00 10.83 ? 367 SER N CB 1 ATOM 2240 O OG . SER A 1 287 ? 56.019 26.044 118.368 1.00 16.46 ? 367 SER N OG 1 ATOM 2241 N N . ILE A 1 288 ? 54.031 27.733 120.313 1.00 7.55 ? 368 ILE N N 1 ATOM 2242 C CA . ILE A 1 288 ? 52.671 27.408 120.733 1.00 4.95 ? 368 ILE N CA 1 ATOM 2243 C C . ILE A 1 288 ? 52.264 26.107 120.128 1.00 5.89 ? 368 ILE N C 1 ATOM 2244 O O . ILE A 1 288 ? 51.307 25.520 120.622 1.00 7.33 ? 368 ILE N O 1 ATOM 2245 C CB . ILE A 1 288 ? 51.621 28.442 120.307 1.00 4.71 ? 368 ILE N CB 1 ATOM 2246 C CG1 . ILE A 1 288 ? 51.701 28.908 118.788 1.00 4.66 ? 368 ILE N CG1 1 ATOM 2247 C CG2 . ILE A 1 288 ? 51.808 29.508 121.369 1.00 2.86 ? 368 ILE N CG2 1 ATOM 2248 C CD1 . ILE A 1 288 ? 51.041 30.216 118.197 1.00 3.84 ? 368 ILE N CD1 1 ATOM 2249 N N . ALA A 1 289 ? 52.989 25.607 119.133 1.00 6.78 ? 369 ALA N N 1 ATOM 2250 C CA . ALA A 1 289 ? 52.597 24.399 118.477 1.00 4.66 ? 369 ALA N CA 1 ATOM 2251 C C . ALA A 1 289 ? 53.620 23.292 118.516 1.00 5.48 ? 369 ALA N C 1 ATOM 2252 O O . ALA A 1 289 ? 53.201 22.164 118.300 1.00 6.40 ? 369 ALA N O 1 ATOM 2253 C CB . ALA A 1 289 ? 52.304 24.673 117.028 1.00 7.20 ? 369 ALA N CB 1 ATOM 2254 N N . SER A 1 290 ? 54.921 23.475 118.770 1.00 5.16 ? 370 SER N N 1 ATOM 2255 C CA . SER A 1 290 ? 55.924 22.387 118.672 1.00 6.51 ? 370 SER N CA 1 ATOM 2256 C C . SER A 1 290 ? 56.905 22.349 119.862 1.00 6.64 ? 370 SER N C 1 ATOM 2257 O O . SER A 1 290 ? 57.116 23.363 120.526 1.00 8.05 ? 370 SER N O 1 ATOM 2258 C CB . SER A 1 290 ? 56.772 22.524 117.394 1.00 6.08 ? 370 SER N CB 1 ATOM 2259 O OG . SER A 1 290 ? 56.093 22.925 116.217 1.00 3.69 ? 370 SER N OG 1 ATOM 2260 N N . ARG A 1 291 ? 57.575 21.248 120.189 1.00 4.76 ? 371 ARG N N 1 ATOM 2261 C CA . ARG A 1 291 ? 58.488 21.200 121.302 1.00 2.53 ? 371 ARG N CA 1 ATOM 2262 C C . ARG A 1 291 ? 59.812 21.754 120.784 1.00 2.07 ? 371 ARG N C 1 ATOM 2263 O O . ARG A 1 291 ? 60.687 20.972 120.373 1.00 2.60 ? 371 ARG N O 1 ATOM 2264 C CB . ARG A 1 291 ? 58.619 19.761 121.739 1.00 2.00 ? 371 ARG N CB 1 ATOM 2265 C CG . ARG A 1 291 ? 57.311 19.295 122.313 1.00 2.00 ? 371 ARG N CG 1 ATOM 2266 C CD . ARG A 1 291 ? 57.261 17.780 122.179 1.00 2.03 ? 371 ARG N CD 1 ATOM 2267 N NE . ARG A 1 291 ? 56.061 17.183 122.772 1.00 4.87 ? 371 ARG N NE 1 ATOM 2268 C CZ . ARG A 1 291 ? 55.840 15.849 122.809 1.00 4.44 ? 371 ARG N CZ 1 ATOM 2269 N NH1 . ARG A 1 291 ? 56.679 14.984 122.242 1.00 2.04 ? 371 ARG N NH1 1 ATOM 2270 N NH2 . ARG A 1 291 ? 54.753 15.346 123.400 1.00 4.22 ? 371 ARG N NH2 1 ATOM 2271 N N . SER A 1 292 ? 59.934 23.094 120.713 1.00 2.41 ? 372 SER N N 1 ATOM 2272 C CA . SER A 1 292 ? 61.155 23.787 120.353 1.00 3.76 ? 372 SER N CA 1 ATOM 2273 C C . SER A 1 292 ? 61.249 24.941 121.313 1.00 4.38 ? 372 SER N C 1 ATOM 2274 O O . SER A 1 292 ? 60.239 25.538 121.689 1.00 6.20 ? 372 SER N O 1 ATOM 2275 C CB . SER A 1 292 ? 61.123 24.303 118.935 1.00 2.04 ? 372 SER N CB 1 ATOM 2276 O OG . SER A 1 292 ? 60.009 25.126 118.656 1.00 4.74 ? 372 SER N OG 1 ATOM 2277 N N . GLY A 1 293 ? 62.453 25.262 121.773 1.00 4.74 ? 373 GLY N N 1 ATOM 2278 C CA . GLY A 1 293 ? 62.667 26.251 122.806 1.00 2.06 ? 373 GLY N CA 1 ATOM 2279 C C . GLY A 1 293 ? 62.204 25.810 124.188 1.00 3.16 ? 373 GLY N C 1 ATOM 2280 O O . GLY A 1 293 ? 61.352 24.939 124.332 1.00 2.00 ? 373 GLY N O 1 ATOM 2281 N N . TYR A 1 294 ? 62.826 26.323 125.244 1.00 3.81 ? 374 TYR N N 1 ATOM 2282 C CA . TYR A 1 294 ? 62.366 26.122 126.588 1.00 3.40 ? 374 TYR N CA 1 ATOM 2283 C C . TYR A 1 294 ? 62.696 27.372 127.368 1.00 5.12 ? 374 TYR N C 1 ATOM 2284 O O . TYR A 1 294 ? 63.838 27.852 127.275 1.00 6.56 ? 374 TYR N O 1 ATOM 2285 C CB . TYR A 1 294 ? 63.070 24.955 127.225 1.00 3.01 ? 374 TYR N CB 1 ATOM 2286 C CG . TYR A 1 294 ? 62.206 24.422 128.314 1.00 4.79 ? 374 TYR N CG 1 ATOM 2287 C CD1 . TYR A 1 294 ? 61.230 23.516 127.981 1.00 4.60 ? 374 TYR N CD1 1 ATOM 2288 C CD2 . TYR A 1 294 ? 62.367 24.896 129.591 1.00 3.59 ? 374 TYR N CD2 1 ATOM 2289 C CE1 . TYR A 1 294 ? 60.369 23.075 128.954 1.00 2.00 ? 374 TYR N CE1 1 ATOM 2290 C CE2 . TYR A 1 294 ? 61.504 24.465 130.576 1.00 2.64 ? 374 TYR N CE2 1 ATOM 2291 C CZ . TYR A 1 294 ? 60.527 23.562 130.230 1.00 2.02 ? 374 TYR N CZ 1 ATOM 2292 O OH . TYR A 1 294 ? 59.700 23.149 131.229 1.00 2.03 ? 374 TYR N OH 1 ATOM 2293 N N . GLU A 1 295 ? 61.782 27.893 128.192 1.00 3.86 ? 375 GLU N N 1 ATOM 2294 C CA . GLU A 1 295 ? 62.055 29.085 128.970 1.00 3.94 ? 375 GLU N CA 1 ATOM 2295 C C . GLU A 1 295 ? 61.442 28.977 130.315 1.00 4.12 ? 375 GLU N C 1 ATOM 2296 O O . GLU A 1 295 ? 60.492 28.203 130.464 1.00 3.97 ? 375 GLU N O 1 ATOM 2297 C CB . GLU A 1 295 ? 61.500 30.301 128.348 1.00 3.46 ? 375 GLU N CB 1 ATOM 2298 C CG . GLU A 1 295 ? 60.151 30.192 127.741 1.00 2.00 ? 375 GLU N CG 1 ATOM 2299 C CD . GLU A 1 295 ? 59.631 31.557 127.348 1.00 2.82 ? 375 GLU N CD 1 ATOM 2300 O OE1 . GLU A 1 295 ? 60.389 32.365 126.802 1.00 2.08 ? 375 GLU N OE1 1 ATOM 2301 O OE2 . GLU A 1 295 ? 58.456 31.804 127.581 1.00 2.05 ? 375 GLU N OE2 1 ATOM 2302 N N . MET A 1 296 ? 61.987 29.754 131.243 1.00 3.23 ? 376 MET N N 1 ATOM 2303 C CA . MET A 1 296 ? 61.580 29.730 132.632 1.00 3.03 ? 376 MET N CA 1 ATOM 2304 C C . MET A 1 296 ? 61.188 31.151 132.866 1.00 3.70 ? 376 MET N C 1 ATOM 2305 O O . MET A 1 296 ? 61.938 32.084 132.599 1.00 2.52 ? 376 MET N O 1 ATOM 2306 C CB . MET A 1 296 ? 62.719 29.370 133.575 1.00 2.00 ? 376 MET N CB 1 ATOM 2307 C CG . MET A 1 296 ? 63.134 27.920 133.528 1.00 2.00 ? 376 MET N CG 1 ATOM 2308 S SD . MET A 1 296 ? 61.798 26.758 133.914 1.00 2.03 ? 376 MET N SD 1 ATOM 2309 C CE . MET A 1 296 ? 61.468 27.056 135.607 1.00 2.00 ? 376 MET N CE 1 ATOM 2310 N N . LEU A 1 297 ? 59.989 31.317 133.376 1.00 2.89 ? 377 LEU N N 1 ATOM 2311 C CA . LEU A 1 297 ? 59.413 32.624 133.575 1.00 2.03 ? 377 LEU N CA 1 ATOM 2312 C C . LEU A 1 297 ? 58.899 32.728 134.983 1.00 3.08 ? 377 LEU N C 1 ATOM 2313 O O . LEU A 1 297 ? 58.347 31.762 135.499 1.00 5.28 ? 377 LEU N O 1 ATOM 2314 C CB . LEU A 1 297 ? 58.246 32.823 132.678 1.00 2.07 ? 377 LEU N CB 1 ATOM 2315 C CG . LEU A 1 297 ? 58.293 32.698 131.161 1.00 3.48 ? 377 LEU N CG 1 ATOM 2316 C CD1 . LEU A 1 297 ? 56.871 32.873 130.632 1.00 4.11 ? 377 LEU N CD1 1 ATOM 2317 C CD2 . LEU A 1 297 ? 59.198 33.743 130.549 1.00 5.31 ? 377 LEU N CD2 1 ATOM 2318 N N . LYS A 1 298 ? 59.090 33.864 135.611 1.00 2.73 ? 378 LYS N N 1 ATOM 2319 C CA . LYS A 1 298 ? 58.695 34.033 136.990 1.00 4.26 ? 378 LYS N CA 1 ATOM 2320 C C . LYS A 1 298 ? 57.341 34.685 136.922 1.00 4.96 ? 378 LYS N C 1 ATOM 2321 O O . LYS A 1 298 ? 57.193 35.785 136.375 1.00 6.78 ? 378 LYS N O 1 ATOM 2322 C CB . LYS A 1 298 ? 59.664 34.925 137.707 1.00 5.56 ? 378 LYS N CB 1 ATOM 2323 C CG . LYS A 1 298 ? 59.128 35.366 139.030 1.00 5.95 ? 378 LYS N CG 1 ATOM 2324 C CD . LYS A 1 298 ? 60.294 36.069 139.688 1.00 7.72 ? 378 LYS N CD 1 ATOM 2325 C CE . LYS A 1 298 ? 59.759 36.766 140.924 1.00 11.27 ? 378 LYS N CE 1 ATOM 2326 N NZ . LYS A 1 298 ? 60.834 36.868 141.885 1.00 16.01 ? 378 LYS N NZ 1 ATOM 2327 N N . VAL A 1 299 ? 56.340 34.040 137.480 1.00 6.44 ? 379 VAL N N 1 ATOM 2328 C CA . VAL A 1 299 ? 54.988 34.539 137.381 1.00 6.59 ? 379 VAL N CA 1 ATOM 2329 C C . VAL A 1 299 ? 54.529 34.452 138.811 1.00 7.80 ? 379 VAL N C 1 ATOM 2330 O O . VAL A 1 299 ? 54.124 33.372 139.237 1.00 8.73 ? 379 VAL N O 1 ATOM 2331 C CB . VAL A 1 299 ? 54.186 33.614 136.432 1.00 7.20 ? 379 VAL N CB 1 ATOM 2332 C CG1 . VAL A 1 299 ? 52.809 34.212 136.403 1.00 6.16 ? 379 VAL N CG1 1 ATOM 2333 C CG2 . VAL A 1 299 ? 54.741 33.503 134.992 1.00 10.51 ? 379 VAL N CG2 1 ATOM 2334 N N . PRO A 1 300 ? 54.636 35.519 139.604 1.00 7.18 ? 380 PRO N N 1 ATOM 2335 C CA . PRO A 1 300 ? 54.274 35.555 141.011 1.00 8.03 ? 380 PRO N CA 1 ATOM 2336 C C . PRO A 1 300 ? 52.815 35.162 141.211 1.00 11.25 ? 380 PRO N C 1 ATOM 2337 O O . PRO A 1 300 ? 51.923 35.526 140.438 1.00 15.78 ? 380 PRO N O 1 ATOM 2338 C CB . PRO A 1 300 ? 54.563 36.952 141.387 1.00 7.75 ? 380 PRO N CB 1 ATOM 2339 C CG . PRO A 1 300 ? 55.593 37.390 140.411 1.00 7.04 ? 380 PRO N CG 1 ATOM 2340 C CD . PRO A 1 300 ? 55.006 36.848 139.147 1.00 6.84 ? 380 PRO N CD 1 ATOM 2341 N N . ASN A 1 301 ? 52.577 34.363 142.236 1.00 12.55 ? 381 ASN N N 1 ATOM 2342 C CA . ASN A 1 301 ? 51.262 33.897 142.590 1.00 13.90 ? 381 ASN N CA 1 ATOM 2343 C C . ASN A 1 301 ? 50.416 33.332 141.470 1.00 12.59 ? 381 ASN N C 1 ATOM 2344 O O . ASN A 1 301 ? 49.185 33.375 141.452 1.00 12.25 ? 381 ASN N O 1 ATOM 2345 C CB . ASN A 1 301 ? 50.565 35.031 143.261 1.00 17.70 ? 381 ASN N CB 1 ATOM 2346 C CG . ASN A 1 301 ? 51.204 35.119 144.617 1.00 20.58 ? 381 ASN N CG 1 ATOM 2347 O OD1 . ASN A 1 301 ? 52.143 35.876 144.780 1.00 23.99 ? 381 ASN N OD1 1 ATOM 2348 N ND2 . ASN A 1 301 ? 50.856 34.293 145.609 1.00 20.23 ? 381 ASN N ND2 1 ATOM 2349 N N . ALA A 1 302 ? 51.139 32.668 140.590 1.00 10.87 ? 382 ALA N N 1 ATOM 2350 C CA . ALA A 1 302 ? 50.604 32.007 139.435 1.00 8.73 ? 382 ALA N CA 1 ATOM 2351 C C . ALA A 1 302 ? 49.482 31.046 139.713 1.00 10.13 ? 382 ALA N C 1 ATOM 2352 O O . ALA A 1 302 ? 48.519 30.970 138.943 1.00 12.63 ? 382 ALA N O 1 ATOM 2353 C CB . ALA A 1 302 ? 51.642 31.198 138.754 1.00 6.16 ? 382 ALA N CB 1 ATOM 2354 N N . LEU A 1 303 ? 49.650 30.271 140.783 1.00 8.53 ? 383 LEU N N 1 ATOM 2355 C CA . LEU A 1 303 ? 48.714 29.224 141.131 1.00 8.99 ? 383 LEU N CA 1 ATOM 2356 C C . LEU A 1 303 ? 47.339 29.770 141.422 1.00 12.41 ? 383 LEU N C 1 ATOM 2357 O O . LEU A 1 303 ? 46.366 29.289 140.860 1.00 14.11 ? 383 LEU N O 1 ATOM 2358 C CB . LEU A 1 303 ? 49.252 28.445 142.335 1.00 5.75 ? 383 LEU N CB 1 ATOM 2359 C CG . LEU A 1 303 ? 48.461 27.253 142.858 1.00 4.49 ? 383 LEU N CG 1 ATOM 2360 C CD1 . LEU A 1 303 ? 48.347 26.201 141.808 1.00 2.42 ? 383 LEU N CD1 1 ATOM 2361 C CD2 . LEU A 1 303 ? 49.195 26.602 143.981 1.00 4.20 ? 383 LEU N CD2 1 ATOM 2362 N N . THR A 1 304 ? 47.314 30.819 142.229 1.00 15.15 ? 384 THR N N 1 ATOM 2363 C CA . THR A 1 304 ? 46.116 31.464 142.714 1.00 14.52 ? 384 THR N CA 1 ATOM 2364 C C . THR A 1 304 ? 45.585 32.697 141.948 1.00 17.39 ? 384 THR N C 1 ATOM 2365 O O . THR A 1 304 ? 44.509 33.201 142.328 1.00 18.90 ? 384 THR N O 1 ATOM 2366 C CB . THR A 1 304 ? 46.405 31.827 144.158 1.00 11.84 ? 384 THR N CB 1 ATOM 2367 O OG1 . THR A 1 304 ? 47.629 32.540 144.126 1.00 9.20 ? 384 THR N OG1 1 ATOM 2368 C CG2 . THR A 1 304 ? 46.629 30.658 145.066 1.00 8.92 ? 384 THR N CG2 1 ATOM 2369 N N . ASP A 1 305 ? 46.211 33.257 140.899 1.00 19.75 ? 385 ASP N N 1 ATOM 2370 C CA . ASP A 1 305 ? 45.741 34.538 140.370 1.00 21.00 ? 385 ASP N CA 1 ATOM 2371 C C . ASP A 1 305 ? 45.208 34.523 138.956 1.00 22.23 ? 385 ASP N C 1 ATOM 2372 O O . ASP A 1 305 ? 46.079 34.313 138.125 1.00 23.99 ? 385 ASP N O 1 ATOM 2373 C CB . ASP A 1 305 ? 46.928 35.514 140.526 1.00 21.00 ? 385 ASP N CB 1 ATOM 2374 C CG . ASP A 1 305 ? 46.838 36.939 139.978 1.00 21.92 ? 385 ASP N CG 1 ATOM 2375 O OD1 . ASP A 1 305 ? 45.742 37.469 139.808 1.00 20.30 ? 385 ASP N OD1 1 ATOM 2376 O OD2 . ASP A 1 305 ? 47.890 37.541 139.747 1.00 23.47 ? 385 ASP N OD2 1 ATOM 2377 N N . ASP A 1 306 ? 43.972 34.814 138.488 1.00 20.64 ? 386 ASP N N 1 ATOM 2378 C CA . ASP A 1 306 ? 43.667 34.643 137.069 1.00 18.40 ? 386 ASP N CA 1 ATOM 2379 C C . ASP A 1 306 ? 44.197 35.780 136.194 1.00 18.01 ? 386 ASP N C 1 ATOM 2380 O O . ASP A 1 306 ? 43.758 35.929 135.068 1.00 17.62 ? 386 ASP N O 1 ATOM 2381 C CB . ASP A 1 306 ? 42.115 34.441 136.898 1.00 19.28 ? 386 ASP N CB 1 ATOM 2382 C CG . ASP A 1 306 ? 41.042 35.552 137.142 1.00 20.66 ? 386 ASP N CG 1 ATOM 2383 O OD1 . ASP A 1 306 ? 41.335 36.682 137.563 1.00 20.64 ? 386 ASP N OD1 1 ATOM 2384 O OD2 . ASP A 1 306 ? 39.855 35.294 136.901 1.00 20.08 ? 386 ASP N OD2 1 ATOM 2385 N N . ARG A 1 307 ? 45.227 36.520 136.615 1.00 18.54 ? 387 ARG N N 1 ATOM 2386 C CA . ARG A 1 307 ? 45.775 37.664 135.912 1.00 18.02 ? 387 ARG N CA 1 ATOM 2387 C C . ARG A 1 307 ? 47.311 37.699 135.976 1.00 18.62 ? 387 ARG N C 1 ATOM 2388 O O . ARG A 1 307 ? 47.936 38.701 135.636 1.00 18.94 ? 387 ARG N O 1 ATOM 2389 C CB . ARG A 1 307 ? 45.174 38.871 136.574 1.00 19.47 ? 387 ARG N CB 1 ATOM 2390 C CG . ARG A 1 307 ? 44.655 40.013 135.740 1.00 21.60 ? 387 ARG N CG 1 ATOM 2391 C CD . ARG A 1 307 ? 43.348 39.564 135.217 1.00 24.63 ? 387 ARG N CD 1 ATOM 2392 N NE . ARG A 1 307 ? 42.210 39.756 136.124 1.00 2.44 ? 387 ARG N NE 1 ATOM 2393 C CZ . ARG A 1 307 ? 41.037 40.266 135.604 1.00 2.33 ? 387 ARG N CZ 1 ATOM 2394 N NH1 . ARG A 1 307 ? 40.928 40.767 134.329 1.00 2.16 ? 387 ARG N NH1 1 ATOM 2395 N NH2 . ARG A 1 307 ? 39.935 40.307 136.362 1.00 2.21 ? 387 ARG N NH2 1 ATOM 2396 N N . SER A 1 308 ? 48.009 36.640 136.418 1.00 20.17 ? 388 SER N N 1 ATOM 2397 C CA . SER A 1 308 ? 49.467 36.693 136.605 1.00 19.42 ? 388 SER N CA 1 ATOM 2398 C C . SER A 1 308 ? 50.340 36.648 135.369 1.00 20.03 ? 388 SER N C 1 ATOM 2399 O O . SER A 1 308 ? 50.492 35.603 134.752 1.00 20.48 ? 388 SER N O 1 ATOM 2400 C CB . SER A 1 308 ? 49.886 35.559 137.574 1.00 19.23 ? 388 SER N CB 1 ATOM 2401 O OG . SER A 1 308 ? 48.813 34.717 137.967 1.00 17.59 ? 388 SER N OG 1 ATOM 2402 N N . LYS A 1 309 ? 50.885 37.773 134.957 1.00 18.91 ? 389 LYS N N 1 ATOM 2403 C CA . LYS A 1 309 ? 51.787 37.786 133.818 1.00 18.64 ? 389 LYS N CA 1 ATOM 2404 C C . LYS A 1 309 ? 53.239 37.767 134.317 1.00 16.83 ? 389 LYS N C 1 ATOM 2405 O O . LYS A 1 309 ? 53.424 38.144 135.472 1.00 19.89 ? 389 LYS N O 1 ATOM 2406 C CB . LYS A 1 309 ? 51.474 39.044 132.966 1.00 21.19 ? 389 LYS N CB 1 ATOM 2407 C CG . LYS A 1 309 ? 50.156 39.081 132.121 1.00 24.86 ? 389 LYS N CG 1 ATOM 2408 C CD . LYS A 1 309 ? 49.920 37.829 131.232 1.00 29.73 ? 389 LYS N CD 1 ATOM 2409 C CE . LYS A 1 309 ? 48.837 37.999 130.154 1.00 34.02 ? 389 LYS N CE 1 ATOM 2410 N NZ . LYS A 1 309 ? 49.347 38.442 128.862 1.00 35.62 ? 389 LYS N NZ 1 ATOM 2411 N N . PRO A 1 310 ? 54.304 37.358 133.611 1.00 13.02 ? 390 PRO N N 1 ATOM 2412 C CA . PRO A 1 310 ? 55.668 37.190 134.130 1.00 11.58 ? 390 PRO N CA 1 ATOM 2413 C C . PRO A 1 310 ? 56.426 38.429 134.569 1.00 10.77 ? 390 PRO N C 1 ATOM 2414 O O . PRO A 1 310 ? 56.112 39.512 134.082 1.00 13.72 ? 390 PRO N O 1 ATOM 2415 C CB . PRO A 1 310 ? 56.385 36.451 133.018 1.00 10.79 ? 390 PRO N CB 1 ATOM 2416 C CG . PRO A 1 310 ? 55.684 37.011 131.813 1.00 10.52 ? 390 PRO N CG 1 ATOM 2417 C CD . PRO A 1 310 ? 54.257 36.846 132.266 1.00 11.30 ? 390 PRO N CD 1 ATOM 2418 N N . THR A 1 311 ? 57.465 38.324 135.404 1.00 8.39 ? 391 THR N N 1 ATOM 2419 C CA . THR A 1 311 ? 58.233 39.496 135.821 1.00 6.65 ? 391 THR N CA 1 ATOM 2420 C C . THR A 1 311 ? 59.739 39.364 135.639 1.00 8.46 ? 391 THR N C 1 ATOM 2421 O O . THR A 1 311 ? 60.481 40.308 135.888 1.00 10.96 ? 391 THR N O 1 ATOM 2422 C CB . THR A 1 311 ? 58.001 39.887 137.335 1.00 5.97 ? 391 THR N CB 1 ATOM 2423 O OG1 . THR A 1 311 ? 57.683 38.726 138.090 1.00 4.86 ? 391 THR N OG1 1 ATOM 2424 C CG2 . THR A 1 311 ? 56.865 40.886 137.469 1.00 10.43 ? 391 THR N CG2 1 ATOM 2425 N N . GLN A 1 312 ? 60.232 38.219 135.183 1.00 7.56 ? 392 GLN N N 1 ATOM 2426 C CA . GLN A 1 312 ? 61.648 37.953 135.002 1.00 5.11 ? 392 GLN N CA 1 ATOM 2427 C C . GLN A 1 312 ? 61.649 36.658 134.214 1.00 5.25 ? 392 GLN N C 1 ATOM 2428 O O . GLN A 1 312 ? 60.701 35.863 134.358 1.00 3.40 ? 392 GLN N O 1 ATOM 2429 C CB . GLN A 1 312 ? 62.362 37.687 136.315 1.00 7.99 ? 392 GLN N CB 1 ATOM 2430 C CG . GLN A 1 312 ? 63.832 37.947 136.091 1.00 11.36 ? 392 GLN N CG 1 ATOM 2431 C CD . GLN A 1 312 ? 64.806 37.397 137.113 1.00 12.32 ? 392 GLN N CD 1 ATOM 2432 O OE1 . GLN A 1 312 ? 65.555 36.455 136.873 1.00 15.68 ? 392 GLN N OE1 1 ATOM 2433 N NE2 . GLN A 1 312 ? 64.924 37.983 138.267 1.00 10.80 ? 392 GLN N NE2 1 ATOM 2434 N N . GLY A 1 313 ? 62.634 36.413 133.359 1.00 5.98 ? 394 GLY N N 1 ATOM 2435 C CA . GLY A 1 313 ? 62.663 35.146 132.658 1.00 6.23 ? 394 GLY N CA 1 ATOM 2436 C C . GLY A 1 313 ? 64.081 34.673 132.473 1.00 6.38 ? 394 GLY N C 1 ATOM 2437 O O . GLY A 1 313 ? 65.010 35.295 132.985 1.00 6.18 ? 394 GLY N O 1 ATOM 2438 N N . GLN A 1 314 ? 64.238 33.553 131.775 1.00 6.64 ? 395 GLN N N 1 ATOM 2439 C CA . GLN A 1 314 ? 65.513 32.970 131.436 1.00 7.50 ? 395 GLN N CA 1 ATOM 2440 C C . GLN A 1 314 ? 65.265 31.969 130.334 1.00 8.58 ? 395 GLN N C 1 ATOM 2441 O O . GLN A 1 314 ? 64.269 31.238 130.373 1.00 13.28 ? 395 GLN N O 1 ATOM 2442 C CB . GLN A 1 314 ? 66.144 32.213 132.583 1.00 6.16 ? 395 GLN N CB 1 ATOM 2443 C CG . GLN A 1 314 ? 67.358 32.949 133.029 1.00 7.59 ? 395 GLN N CG 1 ATOM 2444 C CD . GLN A 1 314 ? 68.466 32.059 133.474 1.00 6.23 ? 395 GLN N CD 1 ATOM 2445 O OE1 . GLN A 1 314 ? 69.066 31.297 132.752 1.00 8.60 ? 395 GLN N OE1 1 ATOM 2446 N NE2 . GLN A 1 314 ? 68.792 32.160 134.717 1.00 8.12 ? 395 GLN N NE2 1 ATOM 2447 N N . THR A 1 315 ? 66.186 31.972 129.367 1.00 8.47 ? 396 THR N N 1 ATOM 2448 C CA . THR A 1 315 ? 66.114 31.108 128.201 1.00 10.00 ? 396 THR N CA 1 ATOM 2449 C C . THR A 1 315 ? 67.069 29.966 128.417 1.00 10.49 ? 396 THR N C 1 ATOM 2450 O O . THR A 1 315 ? 68.223 30.106 128.853 1.00 9.97 ? 396 THR N O 1 ATOM 2451 C CB . THR A 1 315 ? 66.502 31.861 126.988 1.00 10.47 ? 396 THR N CB 1 ATOM 2452 O OG1 . THR A 1 315 ? 65.714 33.044 127.060 1.00 12.19 ? 396 THR N OG1 1 ATOM 2453 C CG2 . THR A 1 315 ? 66.242 31.128 125.710 1.00 9.44 ? 396 THR N CG2 1 ATOM 2454 N N . ILE A 1 316 ? 66.447 28.835 128.166 1.00 10.13 ? 397 ILE N N 1 ATOM 2455 C CA . ILE A 1 316 ? 67.151 27.617 128.378 1.00 9.25 ? 397 ILE N CA 1 ATOM 2456 C C . ILE A 1 316 ? 67.516 27.018 127.031 1.00 8.90 ? 397 ILE N C 1 ATOM 2457 O O . ILE A 1 316 ? 68.672 26.649 126.827 1.00 10.85 ? 397 ILE N O 1 ATOM 2458 C CB . ILE A 1 316 ? 66.259 26.679 129.214 1.00 9.05 ? 397 ILE N CB 1 ATOM 2459 C CG1 . ILE A 1 316 ? 65.777 27.366 130.479 1.00 7.77 ? 397 ILE N CG1 1 ATOM 2460 C CG2 . ILE A 1 316 ? 67.060 25.399 129.500 1.00 8.21 ? 397 ILE N CG2 1 ATOM 2461 C CD1 . ILE A 1 316 ? 66.896 27.718 131.465 1.00 2.10 ? 397 ILE N CD1 1 ATOM 2462 N N . VAL A 1 317 ? 66.578 26.865 126.093 1.00 7.33 ? 398 VAL N N 1 ATOM 2463 C CA . VAL A 1 317 ? 66.844 26.235 124.814 1.00 4.73 ? 398 VAL N CA 1 ATOM 2464 C C . VAL A 1 317 ? 66.290 27.261 123.854 1.00 6.23 ? 398 VAL N C 1 ATOM 2465 O O . VAL A 1 317 ? 65.176 27.723 124.125 1.00 11.50 ? 398 VAL N O 1 ATOM 2466 C CB . VAL A 1 317 ? 66.068 24.913 124.744 1.00 3.54 ? 398 VAL N CB 1 ATOM 2467 C CG1 . VAL A 1 317 ? 65.889 24.435 123.307 1.00 2.03 ? 398 VAL N CG1 1 ATOM 2468 C CG2 . VAL A 1 317 ? 66.851 23.863 125.494 1.00 2.73 ? 398 VAL N CG2 1 ATOM 2469 N N . LEU A 1 318 ? 66.980 27.703 122.789 1.00 6.84 ? 399 LEU N N 1 ATOM 2470 C CA . LEU A 1 318 ? 66.387 28.666 121.856 1.00 5.34 ? 399 LEU N CA 1 ATOM 2471 C C . LEU A 1 318 ? 65.187 28.117 121.090 1.00 8.30 ? 399 LEU N C 1 ATOM 2472 O O . LEU A 1 318 ? 65.038 26.888 120.999 1.00 16.55 ? 399 LEU N O 1 ATOM 2473 C CB . LEU A 1 318 ? 67.361 29.081 120.842 1.00 3.14 ? 399 LEU N CB 1 ATOM 2474 C CG . LEU A 1 318 ? 68.472 29.902 121.267 1.00 2.79 ? 399 LEU N CG 1 ATOM 2475 C CD1 . LEU A 1 318 ? 69.173 30.171 120.006 1.00 4.50 ? 399 LEU N CD1 1 ATOM 2476 C CD2 . LEU A 1 318 ? 68.082 31.227 121.902 1.00 2.00 ? 399 LEU N CD2 1 ATOM 2477 N N . ASN A 1 319 ? 64.317 28.956 120.503 1.00 3.95 ? 400 ASN N N 1 ATOM 2478 C CA . ASN A 1 319 ? 63.207 28.417 119.708 1.00 3.39 ? 400 ASN N CA 1 ATOM 2479 C C . ASN A 1 319 ? 63.623 27.702 118.429 1.00 3.74 ? 400 ASN N C 1 ATOM 2480 O O . ASN A 1 319 ? 62.891 26.853 117.927 1.00 4.88 ? 400 ASN N O 1 ATOM 2481 C CB . ASN A 1 319 ? 62.261 29.557 119.403 1.00 4.54 ? 400 ASN N CB 1 ATOM 2482 C CG . ASN A 1 319 ? 60.983 29.167 118.682 1.00 3.05 ? 400 ASN N CG 1 ATOM 2483 O OD1 . ASN A 1 319 ? 60.260 28.237 119.039 1.00 7.64 ? 400 ASN N OD1 1 ATOM 2484 N ND2 . ASN A 1 319 ? 60.694 29.934 117.652 1.00 2.00 ? 400 ASN N ND2 1 ATOM 2485 N N . THR A 1 320 ? 64.837 28.004 117.936 1.00 3.97 ? 401 THR N N 1 ATOM 2486 C CA . THR A 1 320 ? 65.463 27.308 116.812 1.00 3.35 ? 401 THR N CA 1 ATOM 2487 C C . THR A 1 320 ? 66.077 25.962 117.250 1.00 6.10 ? 401 THR N C 1 ATOM 2488 O O . THR A 1 320 ? 66.701 25.319 116.405 1.00 10.96 ? 401 THR N O 1 ATOM 2489 C CB . THR A 1 320 ? 66.623 28.177 116.116 1.00 2.05 ? 401 THR N CB 1 ATOM 2490 O OG1 . THR A 1 320 ? 67.702 28.462 117.037 1.00 2.00 ? 401 THR N OG1 1 ATOM 2491 C CG2 . THR A 1 320 ? 66.030 29.479 115.561 1.00 2.00 ? 401 THR N CG2 1 ATOM 2492 N N . ASP A 1 321 ? 65.941 25.463 118.486 1.00 4.99 ? 402 ASP N N 1 ATOM 2493 C CA . ASP A 1 321 ? 66.519 24.195 118.910 1.00 4.63 ? 402 ASP N CA 1 ATOM 2494 C C . ASP A 1 321 ? 65.418 23.253 119.417 1.00 2.64 ? 402 ASP N C 1 ATOM 2495 O O . ASP A 1 321 ? 64.329 23.797 119.645 1.00 2.28 ? 402 ASP N O 1 ATOM 2496 C CB . ASP A 1 321 ? 67.535 24.483 119.982 1.00 7.72 ? 402 ASP N CB 1 ATOM 2497 C CG . ASP A 1 321 ? 68.949 24.564 119.434 1.00 8.80 ? 402 ASP N CG 1 ATOM 2498 O OD1 . ASP A 1 321 ? 69.404 23.574 118.832 1.00 9.81 ? 402 ASP N OD1 1 ATOM 2499 O OD2 . ASP A 1 321 ? 69.597 25.595 119.621 1.00 11.58 ? 402 ASP N OD2 1 ATOM 2500 N N . TRP A 1 322 ? 65.524 21.924 119.656 1.00 2.41 ? 403 TRP N N 1 ATOM 2501 C CA . TRP A 1 322 ? 64.340 21.159 120.018 1.00 2.00 ? 403 TRP N CA 1 ATOM 2502 C C . TRP A 1 322 ? 64.360 20.869 121.488 1.00 2.92 ? 403 TRP N C 1 ATOM 2503 O O . TRP A 1 322 ? 65.407 20.818 122.102 1.00 4.33 ? 403 TRP N O 1 ATOM 2504 C CB . TRP A 1 322 ? 64.253 19.833 119.313 1.00 2.00 ? 403 TRP N CB 1 ATOM 2505 C CG . TRP A 1 322 ? 64.015 19.839 117.807 1.00 3.27 ? 403 TRP N CG 1 ATOM 2506 C CD1 . TRP A 1 322 ? 64.977 19.275 117.013 1.00 2.12 ? 403 TRP N CD1 1 ATOM 2507 C CD2 . TRP A 1 322 ? 62.908 20.260 117.082 1.00 3.07 ? 403 TRP N CD2 1 ATOM 2508 N NE1 . TRP A 1 322 ? 64.503 19.313 115.793 1.00 2.00 ? 403 TRP N NE1 1 ATOM 2509 C CE2 . TRP A 1 322 ? 63.273 19.889 115.792 1.00 3.29 ? 403 TRP N CE2 1 ATOM 2510 C CE3 . TRP A 1 322 ? 61.667 20.871 117.266 1.00 2.14 ? 403 TRP N CE3 1 ATOM 2511 C CZ2 . TRP A 1 322 ? 62.417 20.123 114.726 1.00 4.25 ? 403 TRP N CZ2 1 ATOM 2512 C CZ3 . TRP A 1 322 ? 60.819 21.091 116.189 1.00 2.01 ? 403 TRP N CZ3 1 ATOM 2513 C CH2 . TRP A 1 322 ? 61.193 20.726 114.924 1.00 2.00 ? 403 TRP N CH2 1 ATOM 2514 N N . SER A 1 323 ? 63.220 20.712 122.098 1.00 3.17 ? 404 SER N N 1 ATOM 2515 C CA . SER A 1 323 ? 63.166 20.453 123.490 1.00 2.07 ? 404 SER N CA 1 ATOM 2516 C C . SER A 1 323 ? 62.303 19.239 123.691 1.00 3.32 ? 404 SER N C 1 ATOM 2517 O O . SER A 1 323 ? 62.510 18.264 122.971 1.00 5.78 ? 404 SER N O 1 ATOM 2518 C CB . SER A 1 323 ? 62.637 21.687 124.182 1.00 2.08 ? 404 SER N CB 1 ATOM 2519 O OG . SER A 1 323 ? 61.556 22.308 123.531 1.00 4.81 ? 404 SER N OG 1 ATOM 2520 N N . GLY A 1 324 ? 61.375 19.190 124.641 1.00 2.00 ? 405 GLY N N 1 ATOM 2521 C CA . GLY A 1 324 ? 60.598 18.006 124.879 1.00 2.07 ? 405 GLY N CA 1 ATOM 2522 C C . GLY A 1 324 ? 60.036 18.041 126.260 1.00 4.56 ? 405 GLY N C 1 ATOM 2523 O O . GLY A 1 324 ? 59.541 19.063 126.734 1.00 8.67 ? 405 GLY N O 1 ATOM 2524 N N . TYR A 1 325 ? 60.066 16.880 126.868 1.00 4.85 ? 406 TYR N N 1 ATOM 2525 C CA . TYR A 1 325 ? 59.605 16.705 128.222 1.00 4.41 ? 406 TYR N CA 1 ATOM 2526 C C . TYR A 1 325 ? 60.360 17.494 129.262 1.00 6.36 ? 406 TYR N C 1 ATOM 2527 O O . TYR A 1 325 ? 61.555 17.710 129.067 1.00 5.61 ? 406 TYR N O 1 ATOM 2528 C CB . TYR A 1 325 ? 59.702 15.255 128.533 1.00 4.15 ? 406 TYR N CB 1 ATOM 2529 C CG . TYR A 1 325 ? 58.557 14.417 128.029 1.00 5.60 ? 406 TYR N CG 1 ATOM 2530 C CD1 . TYR A 1 325 ? 57.849 14.746 126.914 1.00 2.39 ? 406 TYR N CD1 1 ATOM 2531 C CD2 . TYR A 1 325 ? 58.155 13.381 128.817 1.00 5.80 ? 406 TYR N CD2 1 ATOM 2532 C CE1 . TYR A 1 325 ? 56.707 14.041 126.614 1.00 4.65 ? 406 TYR N CE1 1 ATOM 2533 C CE2 . TYR A 1 325 ? 57.029 12.672 128.519 1.00 6.91 ? 406 TYR N CE2 1 ATOM 2534 C CZ . TYR A 1 325 ? 56.299 13.009 127.424 1.00 6.46 ? 406 TYR N CZ 1 ATOM 2535 O OH . TYR A 1 325 ? 55.139 12.316 127.159 1.00 8.37 ? 406 TYR N OH 1 ATOM 2536 N N . SER A 1 326 ? 59.766 17.991 130.339 1.00 8.77 ? 407 SER N N 1 ATOM 2537 C CA . SER A 1 326 ? 60.576 18.534 131.435 1.00 8.18 ? 407 SER N CA 1 ATOM 2538 C C . SER A 1 326 ? 60.002 18.112 132.771 1.00 6.46 ? 407 SER N C 1 ATOM 2539 O O . SER A 1 326 ? 58.856 17.685 132.795 1.00 5.73 ? 407 SER N O 1 ATOM 2540 C CB . SER A 1 326 ? 60.637 20.039 131.361 1.00 9.91 ? 407 SER N CB 1 ATOM 2541 O OG . SER A 1 326 ? 59.387 20.506 130.908 1.00 12.75 ? 407 SER N OG 1 ATOM 2542 N N . GLY A 1 327 ? 60.687 18.162 133.897 1.00 7.39 ? 408 GLY N N 1 ATOM 2543 C CA . GLY A 1 327 ? 60.140 17.769 135.189 1.00 7.26 ? 408 GLY N CA 1 ATOM 2544 C C . GLY A 1 327 ? 61.045 18.322 136.278 1.00 8.28 ? 408 GLY N C 1 ATOM 2545 O O . GLY A 1 327 ? 62.143 18.850 136.025 1.00 9.03 ? 408 GLY N O 1 ATOM 2546 N N . SER A 1 328 ? 60.566 18.276 137.498 1.00 8.69 ? 409 SER N N 1 ATOM 2547 C CA . SER A 1 328 ? 61.301 18.730 138.655 1.00 6.63 ? 409 SER N CA 1 ATOM 2548 C C . SER A 1 328 ? 61.931 17.550 139.339 1.00 6.19 ? 409 SER N C 1 ATOM 2549 O O . SER A 1 328 ? 61.395 16.431 139.310 1.00 2.01 ? 409 SER N O 1 ATOM 2550 C CB . SER A 1 328 ? 60.369 19.410 139.605 1.00 6.75 ? 409 SER N CB 1 ATOM 2551 O OG . SER A 1 328 ? 59.159 18.654 139.653 1.00 6.10 ? 409 SER N OG 1 ATOM 2552 N N . PHE A 1 329 ? 63.078 17.913 139.933 1.00 6.32 ? 410 PHE N N 1 ATOM 2553 C CA . PHE A 1 329 ? 63.871 17.081 140.856 1.00 7.24 ? 410 PHE N CA 1 ATOM 2554 C C . PHE A 1 329 ? 64.604 18.042 141.828 1.00 7.18 ? 410 PHE N C 1 ATOM 2555 O O . PHE A 1 329 ? 64.738 19.220 141.488 1.00 8.77 ? 410 PHE N O 1 ATOM 2556 C CB . PHE A 1 329 ? 64.896 16.221 140.103 1.00 4.74 ? 410 PHE N CB 1 ATOM 2557 C CG . PHE A 1 329 ? 66.147 16.917 139.562 1.00 3.42 ? 410 PHE N CG 1 ATOM 2558 C CD1 . PHE A 1 329 ? 67.229 17.175 140.377 1.00 2.00 ? 410 PHE N CD1 1 ATOM 2559 C CD2 . PHE A 1 329 ? 66.223 17.240 138.239 1.00 2.57 ? 410 PHE N CD2 1 ATOM 2560 C CE1 . PHE A 1 329 ? 68.373 17.733 139.898 1.00 2.00 ? 410 PHE N CE1 1 ATOM 2561 C CE2 . PHE A 1 329 ? 67.381 17.802 137.747 1.00 2.09 ? 410 PHE N CE2 1 ATOM 2562 C CZ . PHE A 1 329 ? 68.455 18.049 138.571 1.00 2.03 ? 410 PHE N CZ 1 ATOM 2563 N N . MET A 1 330 ? 65.126 17.609 142.987 1.00 6.39 ? 411 MET N N 1 ATOM 2564 C CA . MET A 1 330 ? 65.809 18.427 144.011 1.00 3.73 ? 411 MET N CA 1 ATOM 2565 C C . MET A 1 330 ? 66.794 17.490 144.732 1.00 2.01 ? 411 MET N C 1 ATOM 2566 O O . MET A 1 330 ? 66.607 16.244 144.751 1.00 2.00 ? 411 MET N O 1 ATOM 2567 C CB . MET A 1 330 ? 64.869 18.963 145.115 1.00 2.87 ? 411 MET N CB 1 ATOM 2568 C CG . MET A 1 330 ? 63.727 19.826 144.647 1.00 3.10 ? 411 MET N CG 1 ATOM 2569 S SD . MET A 1 330 ? 63.569 21.435 145.459 1.00 5.89 ? 411 MET N SD 1 ATOM 2570 C CE . MET A 1 330 ? 62.202 21.011 146.511 1.00 6.95 ? 411 MET N CE 1 ATOM 2571 N N . ASP A 1 331 ? 67.853 17.993 145.375 1.00 2.96 ? 412 ASP N N 1 ATOM 2572 C CA . ASP A 1 331 ? 68.692 17.087 146.132 1.00 3.40 ? 412 ASP N CA 1 ATOM 2573 C C . ASP A 1 331 ? 68.246 17.276 147.563 1.00 2.40 ? 412 ASP N C 1 ATOM 2574 O O . ASP A 1 331 ? 68.709 18.169 148.285 1.00 2.01 ? 412 ASP N O 1 ATOM 2575 C CB . ASP A 1 331 ? 70.148 17.463 145.948 1.00 5.69 ? 412 ASP N CB 1 ATOM 2576 C CG . ASP A 1 331 ? 71.246 16.641 146.707 1.00 7.72 ? 412 ASP N CG 1 ATOM 2577 O OD1 . ASP A 1 331 ? 70.991 15.656 147.436 1.00 6.86 ? 412 ASP N OD1 1 ATOM 2578 O OD2 . ASP A 1 331 ? 72.409 17.025 146.571 1.00 10.63 ? 412 ASP N OD2 1 ATOM 2579 N N . TYR A 1 332 A 67.349 16.419 148.021 1.00 3.09 ? 412 TYR N N 1 ATOM 2580 C CA . TYR A 1 332 A 66.872 16.493 149.401 1.00 3.77 ? 412 TYR N CA 1 ATOM 2581 C C . TYR A 1 332 A 67.936 16.316 150.481 1.00 4.46 ? 412 TYR N C 1 ATOM 2582 O O . TYR A 1 332 A 67.753 16.729 151.631 1.00 4.90 ? 412 TYR N O 1 ATOM 2583 C CB . TYR A 1 332 A 65.788 15.474 149.532 1.00 3.91 ? 412 TYR N CB 1 ATOM 2584 C CG . TYR A 1 332 A 64.661 15.924 148.629 1.00 5.21 ? 412 TYR N CG 1 ATOM 2585 C CD1 . TYR A 1 332 A 63.952 17.053 148.936 1.00 7.17 ? 412 TYR N CD1 1 ATOM 2586 C CD2 . TYR A 1 332 A 64.350 15.227 147.474 1.00 5.29 ? 412 TYR N CD2 1 ATOM 2587 C CE1 . TYR A 1 332 A 62.947 17.486 148.085 1.00 7.65 ? 412 TYR N CE1 1 ATOM 2588 C CE2 . TYR A 1 332 A 63.346 15.658 146.613 1.00 8.23 ? 412 TYR N CE2 1 ATOM 2589 C CZ . TYR A 1 332 A 62.638 16.796 146.927 1.00 8.83 ? 412 TYR N CZ 1 ATOM 2590 O OH . TYR A 1 332 A 61.625 17.268 146.115 1.00 12.75 ? 412 TYR N OH 1 ATOM 2591 N N . TRP A 1 333 B 69.097 15.771 150.097 1.00 3.88 ? 412 TRP N N 1 ATOM 2592 C CA . TRP A 1 333 B 70.172 15.527 151.037 1.00 5.29 ? 412 TRP N CA 1 ATOM 2593 C C . TRP A 1 333 B 71.292 16.528 150.814 1.00 6.67 ? 412 TRP N C 1 ATOM 2594 O O . TRP A 1 333 B 72.443 16.335 151.222 1.00 5.99 ? 412 TRP N O 1 ATOM 2595 C CB . TRP A 1 333 B 70.620 14.094 150.839 1.00 3.96 ? 412 TRP N CB 1 ATOM 2596 C CG . TRP A 1 333 B 69.463 13.113 151.007 1.00 2.43 ? 412 TRP N CG 1 ATOM 2597 C CD1 . TRP A 1 333 B 69.234 12.536 152.227 1.00 2.02 ? 412 TRP N CD1 1 ATOM 2598 C CD2 . TRP A 1 333 B 68.558 12.708 150.057 1.00 3.32 ? 412 TRP N CD2 1 ATOM 2599 N NE1 . TRP A 1 333 B 68.185 11.769 152.091 1.00 2.92 ? 412 TRP N NE1 1 ATOM 2600 C CE2 . TRP A 1 333 B 67.766 11.850 150.816 1.00 2.48 ? 412 TRP N CE2 1 ATOM 2601 C CE3 . TRP A 1 333 B 68.274 12.922 148.740 1.00 2.00 ? 412 TRP N CE3 1 ATOM 2602 C CZ2 . TRP A 1 333 B 66.682 11.189 150.292 1.00 2.00 ? 412 TRP N CZ2 1 ATOM 2603 C CZ3 . TRP A 1 333 B 67.199 12.251 148.243 1.00 2.00 ? 412 TRP N CZ3 1 ATOM 2604 C CH2 . TRP A 1 333 B 66.411 11.408 148.986 1.00 2.00 ? 412 TRP N CH2 1 ATOM 2605 N N . ALA A 1 334 ? 70.972 17.618 150.105 1.00 9.84 ? 413 ALA N N 1 ATOM 2606 C CA . ALA A 1 334 ? 71.933 18.665 149.910 1.00 11.11 ? 413 ALA N CA 1 ATOM 2607 C C . ALA A 1 334 ? 71.835 19.552 151.139 1.00 14.38 ? 413 ALA N C 1 ATOM 2608 O O . ALA A 1 334 ? 70.750 20.048 151.534 1.00 17.39 ? 413 ALA N O 1 ATOM 2609 C CB . ALA A 1 334 ? 71.586 19.490 148.743 1.00 8.92 ? 413 ALA N CB 1 ATOM 2610 N N . GLU A 1 335 ? 73.025 19.642 151.756 1.00 16.38 ? 414 GLU N N 1 ATOM 2611 C CA . GLU A 1 335 ? 73.260 20.494 152.918 1.00 16.54 ? 414 GLU N CA 1 ATOM 2612 C C . GLU A 1 335 ? 72.996 21.967 152.567 1.00 15.99 ? 414 GLU N C 1 ATOM 2613 O O . GLU A 1 335 ? 73.584 22.533 151.637 1.00 15.63 ? 414 GLU N O 1 ATOM 2614 C CB . GLU A 1 335 ? 74.695 20.299 153.381 1.00 17.52 ? 414 GLU N CB 1 ATOM 2615 C CG . GLU A 1 335 ? 74.990 18.854 153.755 1.00 18.60 ? 414 GLU N CG 1 ATOM 2616 C CD . GLU A 1 335 ? 76.391 18.657 154.308 1.00 19.36 ? 414 GLU N CD 1 ATOM 2617 O OE1 . GLU A 1 335 ? 76.564 18.796 155.519 1.00 20.16 ? 414 GLU N OE1 1 ATOM 2618 O OE2 . GLU A 1 335 ? 77.303 18.373 153.529 1.00 20.45 ? 414 GLU N OE2 1 ATOM 2619 N N . GLY A 1 336 ? 72.048 22.575 153.277 1.00 16.52 ? 415 GLY N N 1 ATOM 2620 C CA . GLY A 1 336 ? 71.698 23.973 153.085 1.00 16.85 ? 415 GLY N CA 1 ATOM 2621 C C . GLY A 1 336 ? 70.729 24.449 154.152 1.00 14.72 ? 415 GLY N C 1 ATOM 2622 O O . GLY A 1 336 ? 70.537 23.780 155.146 1.00 15.50 ? 415 GLY N O 1 ATOM 2623 N N . GLU A 1 337 ? 70.157 25.633 153.979 1.00 13.63 ? 416 GLU N N 1 ATOM 2624 C CA . GLU A 1 337 ? 69.101 26.168 154.818 1.00 13.30 ? 416 GLU N CA 1 ATOM 2625 C C . GLU A 1 337 ? 67.837 25.802 154.058 1.00 13.29 ? 416 GLU N C 1 ATOM 2626 O O . GLU A 1 337 ? 66.752 25.716 154.630 1.00 16.39 ? 416 GLU N O 1 ATOM 2627 C CB . GLU A 1 337 ? 69.218 27.691 154.925 1.00 15.90 ? 416 GLU N CB 1 ATOM 2628 C CG . GLU A 1 337 ? 70.517 28.199 155.547 1.00 17.94 ? 416 GLU N CG 1 ATOM 2629 C CD . GLU A 1 337 ? 70.669 27.882 157.028 1.00 19.08 ? 416 GLU N CD 1 ATOM 2630 O OE1 . GLU A 1 337 ? 70.175 28.662 157.839 1.00 19.10 ? 416 GLU N OE1 1 ATOM 2631 O OE2 . GLU A 1 337 ? 71.281 26.869 157.367 1.00 20.06 ? 416 GLU N OE2 1 ATOM 2632 N N . CYS A 1 338 ? 67.951 25.439 152.780 1.00 12.33 ? 417 CYS N N 1 ATOM 2633 C CA . CYS A 1 338 ? 66.804 25.315 151.909 1.00 9.14 ? 417 CYS N CA 1 ATOM 2634 C C . CYS A 1 338 ? 67.067 24.412 150.725 1.00 8.58 ? 417 CYS N C 1 ATOM 2635 O O . CYS A 1 338 ? 68.197 23.984 150.451 1.00 7.92 ? 417 CYS N O 1 ATOM 2636 C CB . CYS A 1 338 ? 66.431 26.699 151.434 1.00 8.11 ? 417 CYS N CB 1 ATOM 2637 S SG . CYS A 1 338 ? 67.832 27.537 150.649 1.00 7.77 ? 417 CYS N SG 1 ATOM 2638 N N . TYR A 1 339 ? 65.966 24.167 150.018 1.00 10.09 ? 418 TYR N N 1 ATOM 2639 C CA . TYR A 1 339 ? 65.950 23.307 148.855 1.00 8.96 ? 418 TYR N CA 1 ATOM 2640 C C . TYR A 1 339 ? 66.166 24.169 147.626 1.00 10.53 ? 418 TYR N C 1 ATOM 2641 O O . TYR A 1 339 ? 65.496 25.180 147.397 1.00 12.30 ? 418 TYR N O 1 ATOM 2642 C CB . TYR A 1 339 ? 64.597 22.514 148.782 1.00 7.55 ? 418 TYR N CB 1 ATOM 2643 C CG . TYR A 1 339 ? 64.472 21.395 149.839 1.00 4.60 ? 418 TYR N CG 1 ATOM 2644 C CD1 . TYR A 1 339 ? 65.550 20.548 150.065 1.00 5.15 ? 418 TYR N CD1 1 ATOM 2645 C CD2 . TYR A 1 339 ? 63.321 21.233 150.612 1.00 4.32 ? 418 TYR N CD2 1 ATOM 2646 C CE1 . TYR A 1 339 ? 65.493 19.566 151.035 1.00 5.10 ? 418 TYR N CE1 1 ATOM 2647 C CE2 . TYR A 1 339 ? 63.254 20.251 151.586 1.00 3.69 ? 418 TYR N CE2 1 ATOM 2648 C CZ . TYR A 1 339 ? 64.343 19.430 151.782 1.00 4.73 ? 418 TYR N CZ 1 ATOM 2649 O OH . TYR A 1 339 ? 64.300 18.440 152.748 1.00 6.31 ? 418 TYR N OH 1 ATOM 2650 N N . ARG A 1 340 ? 67.268 23.780 146.974 1.00 10.33 ? 419 ARG N N 1 ATOM 2651 C CA . ARG A 1 340 ? 67.758 24.257 145.677 1.00 10.54 ? 419 ARG N CA 1 ATOM 2652 C C . ARG A 1 340 ? 66.733 23.793 144.640 1.00 10.33 ? 419 ARG N C 1 ATOM 2653 O O . ARG A 1 340 ? 66.458 22.585 144.577 1.00 11.70 ? 419 ARG N O 1 ATOM 2654 C CB . ARG A 1 340 ? 69.113 23.599 145.409 1.00 10.01 ? 419 ARG N CB 1 ATOM 2655 C CG . ARG A 1 340 ? 69.961 23.894 144.181 1.00 8.88 ? 419 ARG N CG 1 ATOM 2656 C CD . ARG A 1 340 ? 70.720 25.151 144.492 1.00 9.65 ? 419 ARG N CD 1 ATOM 2657 N NE . ARG A 1 340 ? 71.996 25.282 143.821 1.00 10.30 ? 419 ARG N NE 1 ATOM 2658 C CZ . ARG A 1 340 ? 72.981 25.935 144.445 1.00 9.96 ? 419 ARG N CZ 1 ATOM 2659 N NH1 . ARG A 1 340 ? 72.916 26.247 145.727 1.00 9.08 ? 419 ARG N NH1 1 ATOM 2660 N NH2 . ARG A 1 340 ? 74.138 26.190 143.868 1.00 8.96 ? 419 ARG N NH2 1 ATOM 2661 N N . ALA A 1 341 ? 66.133 24.640 143.810 1.00 8.82 ? 420 ALA N N 1 ATOM 2662 C CA . ALA A 1 341 ? 65.150 24.095 142.895 1.00 7.48 ? 420 ALA N CA 1 ATOM 2663 C C . ALA A 1 341 ? 65.760 23.784 141.512 1.00 7.94 ? 420 ALA N C 1 ATOM 2664 O O . ALA A 1 341 ? 66.444 24.620 140.890 1.00 9.60 ? 420 ALA N O 1 ATOM 2665 C CB . ALA A 1 341 ? 63.987 25.102 142.810 1.00 9.56 ? 420 ALA N CB 1 ATOM 2666 N N . CYS A 1 342 ? 65.546 22.538 141.064 1.00 6.46 ? 421 CYS N N 1 ATOM 2667 C CA . CYS A 1 342 ? 66.063 22.022 139.799 1.00 4.51 ? 421 CYS N CA 1 ATOM 2668 C C . CYS A 1 342 ? 65.008 21.392 138.910 1.00 3.37 ? 421 CYS N C 1 ATOM 2669 O O . CYS A 1 342 ? 63.966 20.861 139.319 1.00 2.00 ? 421 CYS N O 1 ATOM 2670 C CB . CYS A 1 342 ? 67.140 20.940 139.984 1.00 4.61 ? 421 CYS N CB 1 ATOM 2671 S SG . CYS A 1 342 ? 68.354 21.217 141.262 1.00 3.97 ? 421 CYS N SG 1 ATOM 2672 N N . PHE A 1 343 ? 65.393 21.378 137.657 1.00 2.01 ? 422 PHE N N 1 ATOM 2673 C CA . PHE A 1 343 ? 64.545 20.822 136.646 1.00 2.40 ? 422 PHE N CA 1 ATOM 2674 C C . PHE A 1 343 ? 65.417 20.213 135.599 1.00 3.51 ? 422 PHE N C 1 ATOM 2675 O O . PHE A 1 343 ? 66.607 20.565 135.549 1.00 5.25 ? 422 PHE N O 1 ATOM 2676 C CB . PHE A 1 343 ? 63.717 21.879 135.997 1.00 2.00 ? 422 PHE N CB 1 ATOM 2677 C CG . PHE A 1 343 ? 64.408 22.922 135.116 1.00 2.04 ? 422 PHE N CG 1 ATOM 2678 C CD1 . PHE A 1 343 ? 64.579 22.699 133.761 1.00 2.00 ? 422 PHE N CD1 1 ATOM 2679 C CD2 . PHE A 1 343 ? 64.836 24.109 135.644 1.00 2.04 ? 422 PHE N CD2 1 ATOM 2680 C CE1 . PHE A 1 343 ? 65.176 23.627 132.933 1.00 2.00 ? 422 PHE N CE1 1 ATOM 2681 C CE2 . PHE A 1 343 ? 65.428 25.046 134.825 1.00 3.41 ? 422 PHE N CE2 1 ATOM 2682 C CZ . PHE A 1 343 ? 65.606 24.822 133.465 1.00 4.15 ? 422 PHE N CZ 1 ATOM 2683 N N . TYR A 1 344 ? 64.823 19.365 134.756 1.00 4.27 ? 423 TYR N N 1 ATOM 2684 C CA . TYR A 1 344 ? 65.565 18.866 133.615 1.00 5.36 ? 423 TYR N CA 1 ATOM 2685 C C . TYR A 1 344 ? 64.772 19.152 132.356 1.00 2.92 ? 423 TYR N C 1 ATOM 2686 O O . TYR A 1 344 ? 63.548 19.296 132.469 1.00 5.48 ? 423 TYR N O 1 ATOM 2687 C CB . TYR A 1 344 ? 65.806 17.367 133.738 1.00 4.66 ? 423 TYR N CB 1 ATOM 2688 C CG . TYR A 1 344 ? 64.582 16.502 133.619 1.00 3.40 ? 423 TYR N CG 1 ATOM 2689 C CD1 . TYR A 1 344 ? 63.804 16.248 134.705 1.00 4.70 ? 423 TYR N CD1 1 ATOM 2690 C CD2 . TYR A 1 344 ? 64.259 15.998 132.387 1.00 2.64 ? 423 TYR N CD2 1 ATOM 2691 C CE1 . TYR A 1 344 ? 62.686 15.497 134.568 1.00 4.32 ? 423 TYR N CE1 1 ATOM 2692 C CE2 . TYR A 1 344 ? 63.129 15.250 132.263 1.00 2.06 ? 423 TYR N CE2 1 ATOM 2693 C CZ . TYR A 1 344 ? 62.367 15.012 133.353 1.00 3.41 ? 423 TYR N CZ 1 ATOM 2694 O OH . TYR A 1 344 ? 61.250 14.293 133.130 1.00 3.65 ? 423 TYR N OH 1 ATOM 2695 N N . VAL A 1 345 ? 65.402 19.272 131.179 1.00 3.75 ? 424 VAL N N 1 ATOM 2696 C CA . VAL A 1 345 ? 64.680 19.323 129.924 1.00 2.71 ? 424 VAL N CA 1 ATOM 2697 C C . VAL A 1 345 ? 65.341 18.254 129.094 1.00 2.88 ? 424 VAL N C 1 ATOM 2698 O O . VAL A 1 345 ? 66.566 18.160 129.028 1.00 5.15 ? 424 VAL N O 1 ATOM 2699 C CB . VAL A 1 345 ? 64.829 20.627 129.189 1.00 2.22 ? 424 VAL N CB 1 ATOM 2700 C CG1 . VAL A 1 345 ? 63.918 20.678 127.964 1.00 2.03 ? 424 VAL N CG1 1 ATOM 2701 C CG2 . VAL A 1 345 ? 64.444 21.726 130.138 1.00 2.00 ? 424 VAL N CG2 1 ATOM 2702 N N . GLU A 1 346 ? 64.463 17.428 128.565 1.00 2.01 ? 425 GLU N N 1 ATOM 2703 C CA . GLU A 1 346 ? 64.747 16.392 127.596 1.00 2.10 ? 425 GLU N CA 1 ATOM 2704 C C . GLU A 1 346 ? 64.916 17.025 126.213 1.00 2.03 ? 425 GLU N C 1 ATOM 2705 O O . GLU A 1 346 ? 64.117 17.877 125.838 1.00 2.00 ? 425 GLU N O 1 ATOM 2706 C CB . GLU A 1 346 ? 63.603 15.447 127.525 1.00 3.96 ? 425 GLU N CB 1 ATOM 2707 C CG . GLU A 1 346 ? 63.689 14.512 126.329 1.00 8.28 ? 425 GLU N CG 1 ATOM 2708 C CD . GLU A 1 346 ? 62.404 13.781 126.131 1.00 10.90 ? 425 GLU N CD 1 ATOM 2709 O OE1 . GLU A 1 346 ? 61.402 14.446 125.915 1.00 13.73 ? 425 GLU N OE1 1 ATOM 2710 O OE2 . GLU A 1 346 ? 62.380 12.572 126.206 1.00 13.83 ? 425 GLU N OE2 1 ATOM 2711 N N . LEU A 1 347 ? 65.849 16.636 125.359 1.00 3.62 ? 426 LEU N N 1 ATOM 2712 C CA . LEU A 1 347 ? 66.028 17.300 124.085 1.00 2.64 ? 426 LEU N CA 1 ATOM 2713 C C . LEU A 1 347 ? 65.888 16.221 123.032 1.00 2.00 ? 426 LEU N C 1 ATOM 2714 O O . LEU A 1 347 ? 66.812 15.441 122.787 1.00 2.70 ? 426 LEU N O 1 ATOM 2715 C CB . LEU A 1 347 ? 67.407 17.950 124.094 1.00 2.13 ? 426 LEU N CB 1 ATOM 2716 C CG . LEU A 1 347 ? 67.590 18.936 125.224 1.00 2.00 ? 426 LEU N CG 1 ATOM 2717 C CD1 . LEU A 1 347 ? 69.016 19.347 125.336 1.00 2.01 ? 426 LEU N CD1 1 ATOM 2718 C CD2 . LEU A 1 347 ? 66.761 20.149 124.960 1.00 2.00 ? 426 LEU N CD2 1 ATOM 2719 N N . ILE A 1 348 ? 64.679 16.097 122.473 1.00 2.92 ? 427 ILE N N 1 ATOM 2720 C CA . ILE A 1 348 ? 64.364 15.057 121.507 1.00 2.12 ? 427 ILE N CA 1 ATOM 2721 C C . ILE A 1 348 ? 65.083 15.308 120.208 1.00 2.95 ? 427 ILE N C 1 ATOM 2722 O O . ILE A 1 348 ? 65.243 16.449 119.779 1.00 2.00 ? 427 ILE N O 1 ATOM 2723 C CB . ILE A 1 348 ? 62.865 15.008 121.254 1.00 2.00 ? 427 ILE N CB 1 ATOM 2724 C CG1 . ILE A 1 348 ? 62.054 14.991 122.548 1.00 2.00 ? 427 ILE N CG1 1 ATOM 2725 C CG2 . ILE A 1 348 ? 62.585 13.745 120.468 1.00 2.00 ? 427 ILE N CG2 1 ATOM 2726 C CD1 . ILE A 1 348 ? 60.528 14.962 122.397 1.00 2.00 ? 427 ILE N CD1 1 ATOM 2727 N N . ARG A 1 349 ? 65.616 14.252 119.612 1.00 5.15 ? 428 ARG N N 1 ATOM 2728 C CA . ARG A 1 349 ? 66.176 14.285 118.271 1.00 4.93 ? 428 ARG N CA 1 ATOM 2729 C C . ARG A 1 349 ? 65.707 13.044 117.562 1.00 5.89 ? 428 ARG N C 1 ATOM 2730 O O . ARG A 1 349 ? 65.687 11.969 118.151 1.00 9.65 ? 428 ARG N O 1 ATOM 2731 C CB . ARG A 1 349 ? 67.688 14.226 118.207 1.00 6.02 ? 428 ARG N CB 1 ATOM 2732 C CG . ARG A 1 349 ? 68.422 15.324 118.902 1.00 10.15 ? 428 ARG N CG 1 ATOM 2733 C CD . ARG A 1 349 ? 67.998 16.685 118.408 1.00 12.50 ? 428 ARG N CD 1 ATOM 2734 N NE . ARG A 1 349 ? 68.308 16.933 117.019 1.00 12.88 ? 428 ARG N NE 1 ATOM 2735 C CZ . ARG A 1 349 ? 69.489 17.315 116.621 1.00 14.27 ? 428 ARG N CZ 1 ATOM 2736 N NH1 . ARG A 1 349 ? 70.502 17.422 117.461 1.00 17.96 ? 428 ARG N NH1 1 ATOM 2737 N NH2 . ARG A 1 349 ? 69.662 17.545 115.340 1.00 14.70 ? 428 ARG N NH2 1 ATOM 2738 N N . GLY A 1 350 ? 65.267 13.210 116.315 1.00 5.87 ? 429 GLY N N 1 ATOM 2739 C CA . GLY A 1 350 ? 64.885 12.103 115.457 1.00 6.85 ? 429 GLY N CA 1 ATOM 2740 C C . GLY A 1 350 ? 63.516 12.322 114.867 1.00 9.95 ? 429 GLY N C 1 ATOM 2741 O O . GLY A 1 350 ? 63.024 13.424 114.581 1.00 10.85 ? 429 GLY N O 1 ATOM 2742 N N . ARG A 1 351 ? 62.897 11.188 114.680 1.00 11.85 ? 430 ARG N N 1 ATOM 2743 C CA . ARG A 1 351 ? 61.548 11.162 114.175 1.00 12.43 ? 430 ARG N CA 1 ATOM 2744 C C . ARG A 1 351 ? 60.536 11.644 115.190 1.00 10.96 ? 430 ARG N C 1 ATOM 2745 O O . ARG A 1 351 ? 60.679 11.284 116.361 1.00 10.34 ? 430 ARG N O 1 ATOM 2746 C CB . ARG A 1 351 ? 61.285 9.761 113.755 1.00 17.21 ? 430 ARG N CB 1 ATOM 2747 C CG . ARG A 1 351 ? 61.988 9.607 112.445 1.00 20.39 ? 430 ARG N CG 1 ATOM 2748 C CD . ARG A 1 351 ? 61.646 8.265 111.842 1.00 21.92 ? 430 ARG N CD 1 ATOM 2749 N NE . ARG A 1 351 ? 62.096 8.155 110.457 1.00 28.35 ? 430 ARG N NE 1 ATOM 2750 C CZ . ARG A 1 351 ? 61.242 8.076 109.452 1.00 31.21 ? 430 ARG N CZ 1 ATOM 2751 N NH1 . ARG A 1 351 ? 59.926 8.175 109.673 1.00 36.07 ? 430 ARG N NH1 1 ATOM 2752 N NH2 . ARG A 1 351 ? 61.728 7.956 108.210 1.00 30.58 ? 430 ARG N NH2 1 ATOM 2753 N N . PRO A 1 352 ? 59.479 12.373 114.805 1.00 9.45 ? 431 PRO N N 1 ATOM 2754 C CA . PRO A 1 352 ? 59.059 12.579 113.438 1.00 7.74 ? 431 PRO N CA 1 ATOM 2755 C C . PRO A 1 352 ? 59.623 13.762 112.701 1.00 7.98 ? 431 PRO N C 1 ATOM 2756 O O . PRO A 1 352 ? 59.660 13.693 111.470 1.00 10.19 ? 431 PRO N O 1 ATOM 2757 C CB . PRO A 1 352 ? 57.555 12.601 113.561 1.00 8.67 ? 431 PRO N CB 1 ATOM 2758 C CG . PRO A 1 352 ? 57.324 13.391 114.796 1.00 6.60 ? 431 PRO N CG 1 ATOM 2759 C CD . PRO A 1 352 ? 58.392 12.771 115.702 1.00 7.48 ? 431 PRO N CD 1 ATOM 2760 N N . LYS A 1 353 ? 60.106 14.808 113.379 1.00 8.16 ? 432 LYS N N 1 ATOM 2761 C CA . LYS A 1 353 ? 60.519 16.032 112.689 1.00 10.17 ? 432 LYS N CA 1 ATOM 2762 C C . LYS A 1 353 ? 61.835 16.006 111.912 1.00 11.11 ? 432 LYS N C 1 ATOM 2763 O O . LYS A 1 353 ? 62.038 16.805 111.008 1.00 13.87 ? 432 LYS N O 1 ATOM 2764 C CB . LYS A 1 353 ? 60.582 17.140 113.705 1.00 9.60 ? 432 LYS N CB 1 ATOM 2765 C CG . LYS A 1 353 ? 59.260 17.425 114.315 1.00 10.64 ? 432 LYS N CG 1 ATOM 2766 C CD . LYS A 1 353 ? 58.520 18.470 113.494 1.00 12.18 ? 432 LYS N CD 1 ATOM 2767 C CE . LYS A 1 353 ? 57.086 18.620 113.982 1.00 13.05 ? 432 LYS N CE 1 ATOM 2768 N NZ . LYS A 1 353 ? 56.528 19.865 113.491 1.00 16.23 ? 432 LYS N NZ 1 ATOM 2769 N N . GLU A 1 354 ? 62.758 15.100 112.244 1.00 12.31 ? 433 GLU N N 1 ATOM 2770 C CA . GLU A 1 354 ? 64.052 14.931 111.624 1.00 15.87 ? 433 GLU N CA 1 ATOM 2771 C C . GLU A 1 354 ? 63.944 13.491 111.134 1.00 17.77 ? 433 GLU N C 1 ATOM 2772 O O . GLU A 1 354 ? 64.601 12.551 111.598 1.00 18.97 ? 433 GLU N O 1 ATOM 2773 C CB . GLU A 1 354 ? 65.163 15.044 112.651 1.00 16.90 ? 433 GLU N CB 1 ATOM 2774 C CG . GLU A 1 354 ? 65.218 16.400 113.322 1.00 20.19 ? 433 GLU N CG 1 ATOM 2775 C CD . GLU A 1 354 ? 66.287 16.501 114.384 1.00 22.04 ? 433 GLU N CD 1 ATOM 2776 O OE1 . GLU A 1 354 ? 66.327 15.663 115.270 1.00 22.71 ? 433 GLU N OE1 1 ATOM 2777 O OE2 . GLU A 1 354 ? 67.063 17.449 114.342 1.00 22.48 ? 433 GLU N OE2 1 ATOM 2778 N N . ASP A 1 355 ? 63.115 13.289 110.122 1.00 18.80 ? 434 ASP N N 1 ATOM 2779 C CA . ASP A 1 355 ? 62.848 11.923 109.703 1.00 17.95 ? 434 ASP N CA 1 ATOM 2780 C C . ASP A 1 355 ? 63.855 11.386 108.704 1.00 16.72 ? 434 ASP N C 1 ATOM 2781 O O . ASP A 1 355 ? 63.666 10.326 108.118 1.00 15.79 ? 434 ASP N O 1 ATOM 2782 C CB . ASP A 1 355 ? 61.408 11.857 109.151 1.00 19.34 ? 434 ASP N CB 1 ATOM 2783 C CG . ASP A 1 355 ? 61.183 12.533 107.809 1.00 21.25 ? 434 ASP N CG 1 ATOM 2784 O OD1 . ASP A 1 355 ? 61.885 13.506 107.505 1.00 23.77 ? 434 ASP N OD1 1 ATOM 2785 O OD2 . ASP A 1 355 ? 60.312 12.056 107.057 1.00 19.54 ? 434 ASP N OD2 1 ATOM 2786 N N . LYS A 1 356 ? 64.928 12.139 108.458 1.00 16.00 ? 435 LYS N N 1 ATOM 2787 C CA . LYS A 1 356 ? 66.004 11.662 107.628 1.00 16.57 ? 435 LYS N CA 1 ATOM 2788 C C . LYS A 1 356 ? 66.751 10.502 108.289 1.00 13.48 ? 435 LYS N C 1 ATOM 2789 O O . LYS A 1 356 ? 67.572 9.810 107.673 1.00 13.86 ? 435 LYS N O 1 ATOM 2790 C CB . LYS A 1 356 ? 66.893 12.829 107.382 1.00 22.03 ? 435 LYS N CB 1 ATOM 2791 C CG . LYS A 1 356 ? 66.867 12.971 105.886 1.00 28.03 ? 435 LYS N CG 1 ATOM 2792 C CD . LYS A 1 356 ? 67.199 14.382 105.453 1.00 32.29 ? 435 LYS N CD 1 ATOM 2793 C CE . LYS A 1 356 ? 67.201 14.438 103.927 1.00 37.01 ? 435 LYS N CE 1 ATOM 2794 N NZ . LYS A 1 356 ? 68.382 13.769 103.389 1.00 39.53 ? 435 LYS N NZ 1 ATOM 2795 N N . VAL A 1 357 ? 66.505 10.301 109.581 1.00 9.99 ? 436 VAL N N 1 ATOM 2796 C CA . VAL A 1 357 ? 67.047 9.177 110.294 1.00 5.54 ? 436 VAL N CA 1 ATOM 2797 C C . VAL A 1 357 ? 65.786 8.442 110.662 1.00 3.92 ? 436 VAL N C 1 ATOM 2798 O O . VAL A 1 357 ? 64.724 9.042 110.724 1.00 4.79 ? 436 VAL N O 1 ATOM 2799 C CB . VAL A 1 357 ? 67.830 9.623 111.567 1.00 4.41 ? 436 VAL N CB 1 ATOM 2800 C CG1 . VAL A 1 357 ? 68.988 10.505 111.117 1.00 4.08 ? 436 VAL N CG1 1 ATOM 2801 C CG2 . VAL A 1 357 ? 66.928 10.329 112.594 1.00 2.03 ? 436 VAL N CG2 1 ATOM 2802 N N . TRP A 1 358 ? 65.904 7.173 110.959 1.00 3.65 ? 437 TRP N N 1 ATOM 2803 C CA . TRP A 1 358 ? 64.758 6.390 111.341 1.00 3.22 ? 437 TRP N CA 1 ATOM 2804 C C . TRP A 1 358 ? 64.680 6.162 112.870 1.00 3.04 ? 437 TRP N C 1 ATOM 2805 O O . TRP A 1 358 ? 63.875 5.351 113.336 1.00 2.04 ? 437 TRP N O 1 ATOM 2806 C CB . TRP A 1 358 ? 64.806 5.034 110.583 1.00 7.82 ? 437 TRP N CB 1 ATOM 2807 C CG . TRP A 1 358 ? 64.623 5.044 109.065 1.00 10.70 ? 437 TRP N CG 1 ATOM 2808 C CD1 . TRP A 1 358 ? 65.695 5.281 108.225 1.00 11.73 ? 437 TRP N CD1 1 ATOM 2809 C CD2 . TRP A 1 358 ? 63.446 4.919 108.349 1.00 12.16 ? 437 TRP N CD2 1 ATOM 2810 N NE1 . TRP A 1 358 ? 65.223 5.332 106.996 1.00 12.98 ? 437 TRP N NE1 1 ATOM 2811 C CE2 . TRP A 1 358 ? 63.892 5.120 107.032 1.00 12.92 ? 437 TRP N CE2 1 ATOM 2812 C CE3 . TRP A 1 358 ? 62.097 4.690 108.556 1.00 11.58 ? 437 TRP N CE3 1 ATOM 2813 C CZ2 . TRP A 1 358 ? 63.041 5.107 105.942 1.00 12.74 ? 437 TRP N CZ2 1 ATOM 2814 C CZ3 . TRP A 1 358 ? 61.231 4.676 107.465 1.00 10.83 ? 437 TRP N CZ3 1 ATOM 2815 C CH2 . TRP A 1 358 ? 61.700 4.883 106.174 1.00 12.42 ? 437 TRP N CH2 1 ATOM 2816 N N . TRP A 1 359 ? 65.443 6.831 113.742 1.00 2.01 ? 438 TRP N N 1 ATOM 2817 C CA . TRP A 1 359 ? 65.429 6.588 115.170 1.00 2.03 ? 438 TRP N CA 1 ATOM 2818 C C . TRP A 1 359 ? 64.920 7.834 115.831 1.00 4.19 ? 438 TRP N C 1 ATOM 2819 O O . TRP A 1 359 ? 65.012 8.907 115.222 1.00 6.24 ? 438 TRP N O 1 ATOM 2820 C CB . TRP A 1 359 ? 66.813 6.308 115.727 1.00 2.06 ? 438 TRP N CB 1 ATOM 2821 C CG . TRP A 1 359 ? 67.989 7.217 115.321 1.00 2.73 ? 438 TRP N CG 1 ATOM 2822 C CD1 . TRP A 1 359 ? 68.804 6.734 114.366 1.00 2.12 ? 438 TRP N CD1 1 ATOM 2823 C CD2 . TRP A 1 359 ? 68.377 8.467 115.801 1.00 3.02 ? 438 TRP N CD2 1 ATOM 2824 N NE1 . TRP A 1 359 ? 69.692 7.648 114.225 1.00 2.00 ? 438 TRP N NE1 1 ATOM 2825 C CE2 . TRP A 1 359 ? 69.506 8.687 115.043 1.00 2.72 ? 438 TRP N CE2 1 ATOM 2826 C CE3 . TRP A 1 359 ? 68.025 9.462 116.726 1.00 2.44 ? 438 TRP N CE3 1 ATOM 2827 C CZ2 . TRP A 1 359 ? 70.277 9.849 115.193 1.00 2.00 ? 438 TRP N CZ2 1 ATOM 2828 C CZ3 . TRP A 1 359 ? 68.778 10.619 116.892 1.00 2.00 ? 438 TRP N CZ3 1 ATOM 2829 C CH2 . TRP A 1 359 ? 69.902 10.810 116.122 1.00 2.45 ? 438 TRP N CH2 1 ATOM 2830 N N . THR A 1 360 ? 64.324 7.772 116.996 1.00 6.09 ? 439 THR N N 1 ATOM 2831 C CA . THR A 1 360 ? 64.060 8.980 117.756 1.00 6.78 ? 439 THR N CA 1 ATOM 2832 C C . THR A 1 360 ? 65.047 8.827 118.921 1.00 6.06 ? 439 THR N C 1 ATOM 2833 O O . THR A 1 360 ? 65.466 7.693 119.172 1.00 9.99 ? 439 THR N O 1 ATOM 2834 C CB . THR A 1 360 ? 62.611 8.976 118.220 1.00 7.07 ? 439 THR N CB 1 ATOM 2835 O OG1 . THR A 1 360 ? 61.808 8.811 117.044 1.00 7.39 ? 439 THR N OG1 1 ATOM 2836 C CG2 . THR A 1 360 ? 62.243 10.263 118.940 1.00 6.02 ? 439 THR N CG2 1 ATOM 2837 N N . SER A 1 361 ? 65.495 9.860 119.645 1.00 3.74 ? 440 SER N N 1 ATOM 2838 C CA . SER A 1 361 ? 66.369 9.704 120.791 1.00 3.43 ? 440 SER N CA 1 ATOM 2839 C C . SER A 1 361 ? 66.409 11.040 121.473 1.00 3.67 ? 440 SER N C 1 ATOM 2840 O O . SER A 1 361 ? 65.621 11.914 121.124 1.00 4.77 ? 440 SER N O 1 ATOM 2841 C CB . SER A 1 361 ? 67.787 9.349 120.417 1.00 3.48 ? 440 SER N CB 1 ATOM 2842 O OG . SER A 1 361 ? 68.387 8.756 121.574 1.00 4.56 ? 440 SER N OG 1 ATOM 2843 N N . ASN A 1 362 ? 67.289 11.250 122.445 1.00 3.24 ? 441 ASN N N 1 ATOM 2844 C CA . ASN A 1 362 ? 67.329 12.512 123.121 1.00 4.69 ? 441 ASN N CA 1 ATOM 2845 C C . ASN A 1 362 ? 68.605 12.606 123.912 1.00 4.79 ? 441 ASN N C 1 ATOM 2846 O O . ASN A 1 362 ? 69.387 11.657 124.014 1.00 6.58 ? 441 ASN N O 1 ATOM 2847 C CB . ASN A 1 362 ? 66.134 12.647 124.063 1.00 5.32 ? 441 ASN N CB 1 ATOM 2848 C CG . ASN A 1 362 ? 66.198 11.687 125.226 1.00 5.52 ? 441 ASN N CG 1 ATOM 2849 O OD1 . ASN A 1 362 ? 66.274 12.112 126.375 1.00 6.20 ? 441 ASN N OD1 1 ATOM 2850 N ND2 . ASN A 1 362 ? 66.184 10.369 125.009 1.00 4.96 ? 441 ASN N ND2 1 ATOM 2851 N N . SER A 1 363 ? 68.871 13.819 124.348 1.00 2.13 ? 442 SER N N 1 ATOM 2852 C CA . SER A 1 363 ? 69.877 14.096 125.356 1.00 2.85 ? 442 SER N CA 1 ATOM 2853 C C . SER A 1 363 ? 69.149 14.850 126.478 1.00 4.07 ? 442 SER N C 1 ATOM 2854 O O . SER A 1 363 ? 67.927 14.940 126.444 1.00 8.13 ? 442 SER N O 1 ATOM 2855 C CB . SER A 1 363 ? 71.009 14.929 124.775 1.00 3.78 ? 442 SER N CB 1 ATOM 2856 O OG . SER A 1 363 ? 70.654 16.244 124.443 1.00 8.78 ? 442 SER N OG 1 ATOM 2857 N N . ILE A 1 364 ? 69.858 15.420 127.453 1.00 3.01 ? 443 ILE N N 1 ATOM 2858 C CA . ILE A 1 364 ? 69.354 16.048 128.661 1.00 2.56 ? 443 ILE N CA 1 ATOM 2859 C C . ILE A 1 364 ? 70.165 17.311 128.972 1.00 2.84 ? 443 ILE N C 1 ATOM 2860 O O . ILE A 1 364 ? 71.375 17.353 128.738 1.00 3.87 ? 443 ILE N O 1 ATOM 2861 C CB . ILE A 1 364 ? 69.490 15.082 129.824 1.00 2.00 ? 443 ILE N CB 1 ATOM 2862 C CG1 . ILE A 1 364 ? 68.814 13.774 129.521 1.00 2.05 ? 443 ILE N CG1 1 ATOM 2863 C CG2 . ILE A 1 364 ? 68.849 15.705 131.047 1.00 2.00 ? 443 ILE N CG2 1 ATOM 2864 C CD1 . ILE A 1 364 ? 69.215 12.711 130.544 1.00 2.08 ? 443 ILE N CD1 1 ATOM 2865 N N . VAL A 1 365 ? 69.491 18.316 129.518 1.00 2.00 ? 444 VAL N N 1 ATOM 2866 C CA . VAL A 1 365 ? 70.098 19.531 130.069 1.00 2.06 ? 444 VAL N CA 1 ATOM 2867 C C . VAL A 1 365 ? 69.468 19.552 131.456 1.00 2.32 ? 444 VAL N C 1 ATOM 2868 O O . VAL A 1 365 ? 68.298 19.114 131.545 1.00 3.96 ? 444 VAL N O 1 ATOM 2869 C CB . VAL A 1 365 ? 69.663 20.899 129.537 1.00 2.00 ? 444 VAL N CB 1 ATOM 2870 C CG1 . VAL A 1 365 ? 70.884 21.681 129.183 1.00 2.00 ? 444 VAL N CG1 1 ATOM 2871 C CG2 . VAL A 1 365 ? 68.700 20.760 128.434 1.00 2.06 ? 444 VAL N CG2 1 ATOM 2872 N N . SER A 1 366 ? 70.095 20.014 132.545 1.00 3.23 ? 445 SER N N 1 ATOM 2873 C CA . SER A 1 366 ? 69.365 20.183 133.775 1.00 5.02 ? 445 SER N CA 1 ATOM 2874 C C . SER A 1 366 ? 69.976 21.422 134.379 1.00 5.95 ? 445 SER N C 1 ATOM 2875 O O . SER A 1 366 ? 71.159 21.715 134.146 1.00 9.60 ? 445 SER N O 1 ATOM 2876 C CB . SER A 1 366 ? 69.507 18.975 134.741 1.00 4.81 ? 445 SER N CB 1 ATOM 2877 O OG . SER A 1 366 ? 70.653 18.152 134.594 1.00 9.31 ? 445 SER N OG 1 ATOM 2878 N N . MET A 1 367 ? 69.159 22.138 135.141 1.00 3.42 ? 446 MET N N 1 ATOM 2879 C CA . MET A 1 367 ? 69.506 23.371 135.845 1.00 3.02 ? 446 MET N CA 1 ATOM 2880 C C . MET A 1 367 ? 69.086 23.243 137.282 1.00 2.61 ? 446 MET N C 1 ATOM 2881 O O . MET A 1 367 ? 68.153 22.491 137.592 1.00 8.00 ? 446 MET N O 1 ATOM 2882 C CB . MET A 1 367 ? 68.729 24.543 135.418 1.00 3.48 ? 446 MET N CB 1 ATOM 2883 C CG . MET A 1 367 ? 69.416 25.584 134.630 1.00 3.71 ? 446 MET N CG 1 ATOM 2884 S SD . MET A 1 367 ? 69.676 24.895 133.027 1.00 7.11 ? 446 MET N SD 1 ATOM 2885 C CE . MET A 1 367 ? 70.698 26.296 132.695 1.00 2.10 ? 446 MET N CE 1 ATOM 2886 N N . CYS A 1 368 ? 69.727 24.022 138.132 1.00 2.01 ? 447 CYS N N 1 ATOM 2887 C CA . CYS A 1 368 ? 69.277 24.168 139.498 1.00 2.00 ? 447 CYS N CA 1 ATOM 2888 C C . CYS A 1 368 ? 69.247 25.660 139.721 1.00 3.97 ? 447 CYS N C 1 ATOM 2889 O O . CYS A 1 368 ? 69.749 26.380 138.839 1.00 6.95 ? 447 CYS N O 1 ATOM 2890 C CB . CYS A 1 368 ? 70.237 23.483 140.452 1.00 2.05 ? 447 CYS N CB 1 ATOM 2891 S SG . CYS A 1 368 ? 70.115 21.688 140.367 1.00 4.04 ? 447 CYS N SG 1 ATOM 2892 N N . SER A 1 369 ? 68.705 26.188 140.821 1.00 3.45 ? 448 SER N N 1 ATOM 2893 C CA . SER A 1 369 ? 68.593 27.618 140.963 1.00 2.00 ? 448 SER N CA 1 ATOM 2894 C C . SER A 1 369 ? 69.678 28.221 141.770 1.00 2.37 ? 448 SER N C 1 ATOM 2895 O O . SER A 1 369 ? 70.229 27.596 142.645 1.00 6.32 ? 448 SER N O 1 ATOM 2896 C CB . SER A 1 369 ? 67.271 27.996 141.589 1.00 2.03 ? 448 SER N CB 1 ATOM 2897 O OG . SER A 1 369 ? 67.116 27.966 143.010 1.00 5.74 ? 448 SER N OG 1 ATOM 2898 N N . SER A 1 370 ? 69.928 29.462 141.464 1.00 2.00 ? 449 SER N N 1 ATOM 2899 C CA . SER A 1 370 ? 70.882 30.298 142.141 1.00 2.11 ? 449 SER N CA 1 ATOM 2900 C C . SER A 1 370 ? 70.125 31.525 142.611 1.00 2.12 ? 449 SER N C 1 ATOM 2901 O O . SER A 1 370 ? 69.141 31.938 142.011 1.00 4.73 ? 449 SER N O 1 ATOM 2902 C CB . SER A 1 370 ? 71.983 30.707 141.191 1.00 5.30 ? 449 SER N CB 1 ATOM 2903 O OG . SER A 1 370 ? 72.717 31.824 141.683 1.00 11.37 ? 449 SER N OG 1 ATOM 2904 N N . THR A 1 371 ? 70.593 32.154 143.661 1.00 5.11 ? 450 THR N N 1 ATOM 2905 C CA . THR A 1 371 ? 70.008 33.352 144.245 1.00 8.30 ? 450 THR N CA 1 ATOM 2906 C C . THR A 1 371 ? 70.649 34.622 143.648 1.00 13.19 ? 450 THR N C 1 ATOM 2907 O O . THR A 1 371 ? 70.188 35.767 143.740 1.00 18.05 ? 450 THR N O 1 ATOM 2908 C CB . THR A 1 371 ? 70.237 33.240 145.740 1.00 7.61 ? 450 THR N CB 1 ATOM 2909 O OG1 . THR A 1 371 ? 71.634 32.979 145.912 1.00 5.95 ? 450 THR N OG1 1 ATOM 2910 C CG2 . THR A 1 371 ? 69.420 32.133 146.388 1.00 5.39 ? 450 THR N CG2 1 ATOM 2911 N N . GLU A 1 372 ? 71.848 34.439 143.082 1.00 14.76 ? 451 GLU N N 1 ATOM 2912 C CA . GLU A 1 372 ? 72.563 35.463 142.350 1.00 15.80 ? 451 GLU N CA 1 ATOM 2913 C C . GLU A 1 372 ? 71.732 35.606 141.108 1.00 12.71 ? 451 GLU N C 1 ATOM 2914 O O . GLU A 1 372 ? 71.000 34.666 140.748 1.00 14.36 ? 451 GLU N O 1 ATOM 2915 C CB . GLU A 1 372 ? 73.899 34.994 141.895 1.00 20.86 ? 451 GLU N CB 1 ATOM 2916 C CG . GLU A 1 372 ? 74.947 34.936 142.985 1.00 28.85 ? 451 GLU N CG 1 ATOM 2917 C CD . GLU A 1 372 ? 75.536 36.304 143.316 1.00 34.05 ? 451 GLU N CD 1 ATOM 2918 O OE1 . GLU A 1 372 ? 75.744 37.107 142.386 1.00 36.98 ? 451 GLU N OE1 1 ATOM 2919 O OE2 . GLU A 1 372 ? 75.780 36.547 144.512 1.00 37.48 ? 451 GLU N OE2 1 ATOM 2920 N N . PHE A 1 373 ? 71.870 36.711 140.378 1.00 9.74 ? 452 PHE N N 1 ATOM 2921 C CA . PHE A 1 373 ? 71.116 36.811 139.146 1.00 8.27 ? 452 PHE N CA 1 ATOM 2922 C C . PHE A 1 373 ? 72.113 36.542 138.039 1.00 9.32 ? 452 PHE N C 1 ATOM 2923 O O . PHE A 1 373 ? 72.644 37.473 137.444 1.00 12.56 ? 452 PHE N O 1 ATOM 2924 C CB . PHE A 1 373 ? 70.521 38.194 138.993 1.00 5.02 ? 452 PHE N CB 1 ATOM 2925 C CG . PHE A 1 373 ? 69.287 38.482 139.815 1.00 3.77 ? 452 PHE N CG 1 ATOM 2926 C CD1 . PHE A 1 373 ? 69.384 38.677 141.160 1.00 4.42 ? 452 PHE N CD1 1 ATOM 2927 C CD2 . PHE A 1 373 ? 68.079 38.609 139.193 1.00 3.00 ? 452 PHE N CD2 1 ATOM 2928 C CE1 . PHE A 1 373 ? 68.277 39.003 141.914 1.00 2.60 ? 452 PHE N CE1 1 ATOM 2929 C CE2 . PHE A 1 373 ? 66.986 38.949 139.944 1.00 2.08 ? 452 PHE N CE2 1 ATOM 2930 C CZ . PHE A 1 373 ? 67.071 39.149 141.308 1.00 2.00 ? 452 PHE N CZ 1 ATOM 2931 N N . LEU A 1 374 ? 72.431 35.285 137.772 1.00 7.23 ? 453 LEU N N 1 ATOM 2932 C CA . LEU A 1 374 ? 73.423 34.966 136.772 1.00 5.16 ? 453 LEU N CA 1 ATOM 2933 C C . LEU A 1 374 ? 72.995 35.199 135.338 1.00 5.78 ? 453 LEU N C 1 ATOM 2934 O O . LEU A 1 374 ? 71.803 35.302 135.039 1.00 7.67 ? 453 LEU N O 1 ATOM 2935 C CB . LEU A 1 374 ? 73.813 33.550 136.944 1.00 3.66 ? 453 LEU N CB 1 ATOM 2936 C CG . LEU A 1 374 ? 74.273 33.222 138.315 1.00 2.02 ? 453 LEU N CG 1 ATOM 2937 C CD1 . LEU A 1 374 ? 74.135 31.730 138.445 1.00 2.04 ? 453 LEU N CD1 1 ATOM 2938 C CD2 . LEU A 1 374 ? 75.659 33.766 138.572 1.00 2.01 ? 453 LEU N CD2 1 ATOM 2939 N N . GLY A 1 375 ? 73.990 35.300 134.457 1.00 5.21 ? 454 GLY N N 1 ATOM 2940 C CA . GLY A 1 375 ? 73.773 35.471 133.039 1.00 6.77 ? 454 GLY N CA 1 ATOM 2941 C C . GLY A 1 375 ? 73.209 34.197 132.477 1.00 6.49 ? 454 GLY N C 1 ATOM 2942 O O . GLY A 1 375 ? 73.346 33.132 133.064 1.00 10.67 ? 454 GLY N O 1 ATOM 2943 N N . GLN A 1 376 ? 72.539 34.259 131.351 1.00 5.51 ? 455 GLN N N 1 ATOM 2944 C CA . GLN A 1 376 ? 71.969 33.066 130.702 1.00 4.45 ? 455 GLN N CA 1 ATOM 2945 C C . GLN A 1 376 ? 72.705 32.634 129.433 1.00 5.11 ? 455 GLN N C 1 ATOM 2946 O O . GLN A 1 376 ? 73.317 33.468 128.751 1.00 8.31 ? 455 GLN N O 1 ATOM 2947 C CB . GLN A 1 376 ? 70.491 33.300 130.340 1.00 6.79 ? 455 GLN N CB 1 ATOM 2948 C CG . GLN A 1 376 ? 70.229 34.604 129.588 1.00 8.27 ? 455 GLN N CG 1 ATOM 2949 C CD . GLN A 1 376 ? 68.794 34.858 129.176 1.00 7.90 ? 455 GLN N CD 1 ATOM 2950 O OE1 . GLN A 1 376 ? 68.568 35.511 128.173 1.00 8.92 ? 455 GLN N OE1 1 ATOM 2951 N NE2 . GLN A 1 376 ? 67.718 34.532 129.855 1.00 6.52 ? 455 GLN N NE2 1 ATOM 2952 N N . TRP A 1 377 ? 72.736 31.325 129.156 1.00 3.73 ? 456 TRP N N 1 ATOM 2953 C CA . TRP A 1 377 ? 73.211 30.838 127.877 1.00 2.46 ? 456 TRP N CA 1 ATOM 2954 C C . TRP A 1 377 ? 72.060 29.996 127.364 1.00 3.01 ? 456 TRP N C 1 ATOM 2955 O O . TRP A 1 377 ? 71.040 29.880 128.050 1.00 2.00 ? 456 TRP N O 1 ATOM 2956 C CB . TRP A 1 377 ? 74.465 29.973 128.028 1.00 2.01 ? 456 TRP N CB 1 ATOM 2957 C CG . TRP A 1 377 ? 75.402 29.917 126.825 1.00 2.00 ? 456 TRP N CG 1 ATOM 2958 C CD1 . TRP A 1 377 ? 75.102 30.596 125.677 1.00 2.00 ? 456 TRP N CD1 1 ATOM 2959 C CD2 . TRP A 1 377 ? 76.601 29.247 126.741 1.00 3.28 ? 456 TRP N CD2 1 ATOM 2960 N NE1 . TRP A 1 377 ? 76.096 30.395 124.859 1.00 2.18 ? 456 TRP N NE1 1 ATOM 2961 C CE2 . TRP A 1 377 ? 77.002 29.606 125.453 1.00 3.38 ? 456 TRP N CE2 1 ATOM 2962 C CE3 . TRP A 1 377 ? 77.459 28.433 127.483 1.00 2.03 ? 456 TRP N CE3 1 ATOM 2963 C CZ2 . TRP A 1 377 ? 78.201 29.167 124.899 1.00 2.12 ? 456 TRP N CZ2 1 ATOM 2964 C CZ3 . TRP A 1 377 ? 78.666 27.990 126.926 1.00 2.05 ? 456 TRP N CZ3 1 ATOM 2965 C CH2 . TRP A 1 377 ? 79.029 28.364 125.642 1.00 2.00 ? 456 TRP N CH2 1 ATOM 2966 N N . ASN A 1 378 ? 72.160 29.417 126.199 1.00 4.50 ? 457 ASN N N 1 ATOM 2967 C CA . ASN A 1 378 ? 71.111 28.586 125.632 1.00 6.23 ? 457 ASN N CA 1 ATOM 2968 C C . ASN A 1 378 ? 71.838 27.333 125.215 1.00 6.69 ? 457 ASN N C 1 ATOM 2969 O O . ASN A 1 378 ? 73.000 27.437 124.803 1.00 8.29 ? 457 ASN N O 1 ATOM 2970 C CB . ASN A 1 378 ? 70.448 29.219 124.428 1.00 7.50 ? 457 ASN N CB 1 ATOM 2971 C CG . ASN A 1 378 ? 71.399 29.599 123.340 1.00 9.18 ? 457 ASN N CG 1 ATOM 2972 O OD1 . ASN A 1 378 ? 71.456 28.990 122.288 1.00 9.57 ? 457 ASN N OD1 1 ATOM 2973 N ND2 . ASN A 1 378 ? 72.318 30.238 123.804 1.00 2.21 ? 457 ASN N ND2 1 ATOM 2974 N N . TRP A 1 379 ? 71.412 26.146 125.523 1.00 5.65 ? 458 TRP N N 1 ATOM 2975 C CA . TRP A 1 379 ? 72.002 24.793 125.600 1.00 4.61 ? 458 TRP N CA 1 ATOM 2976 C C . TRP A 1 379 ? 71.328 23.766 124.659 1.00 4.83 ? 458 TRP N C 1 ATOM 2977 O O . TRP A 1 379 ? 70.409 23.058 125.076 1.00 2.88 ? 458 TRP N O 1 ATOM 2978 C CB . TRP A 1 379 ? 71.904 24.307 127.064 1.00 2.61 ? 458 TRP N CB 1 ATOM 2979 C CG . TRP A 1 379 ? 72.572 25.299 128.016 1.00 4.69 ? 458 TRP N CG 1 ATOM 2980 C CD1 . TRP A 1 379 ? 71.981 26.356 128.585 1.00 5.28 ? 458 TRP N CD1 1 ATOM 2981 C CD2 . TRP A 1 379 ? 73.922 25.240 128.421 1.00 6.54 ? 458 TRP N CD2 1 ATOM 2982 N NE1 . TRP A 1 379 ? 72.967 27.008 129.334 1.00 3.58 ? 458 TRP N NE1 1 ATOM 2983 C CE2 . TRP A 1 379 ? 74.108 26.348 129.224 1.00 6.13 ? 458 TRP N CE2 1 ATOM 2984 C CE3 . TRP A 1 379 ? 75.007 24.375 128.175 1.00 4.68 ? 458 TRP N CE3 1 ATOM 2985 C CZ2 . TRP A 1 379 ? 75.334 26.665 129.792 1.00 7.91 ? 458 TRP N CZ2 1 ATOM 2986 C CZ3 . TRP A 1 379 ? 76.239 24.701 128.764 1.00 2.00 ? 458 TRP N CZ3 1 ATOM 2987 C CH2 . TRP A 1 379 ? 76.391 25.797 129.533 1.00 5.16 ? 458 TRP N CH2 1 ATOM 2988 N N . PRO A 1 380 ? 71.839 23.779 123.428 1.00 6.18 ? 459 PRO N N 1 ATOM 2989 C CA . PRO A 1 380 ? 71.513 22.864 122.324 1.00 8.09 ? 459 PRO N CA 1 ATOM 2990 C C . PRO A 1 380 ? 71.975 21.443 122.530 1.00 11.24 ? 459 PRO N C 1 ATOM 2991 O O . PRO A 1 380 ? 73.101 21.215 123.062 1.00 12.67 ? 459 PRO N O 1 ATOM 2992 C CB . PRO A 1 380 ? 72.341 23.359 121.153 1.00 7.98 ? 459 PRO N CB 1 ATOM 2993 C CG . PRO A 1 380 ? 73.137 24.554 121.639 1.00 10.11 ? 459 PRO N CG 1 ATOM 2994 C CD . PRO A 1 380 ? 72.787 24.817 123.067 1.00 8.82 ? 459 PRO N CD 1 ATOM 2995 N N . ASP A 1 381 ? 71.146 20.504 122.101 1.00 15.76 ? 460 ASP N N 1 ATOM 2996 C CA . ASP A 1 381 ? 71.542 19.094 122.098 1.00 17.40 ? 460 ASP N CA 1 ATOM 2997 C C . ASP A 1 381 ? 72.901 19.068 121.418 1.00 21.23 ? 460 ASP N C 1 ATOM 2998 O O . ASP A 1 381 ? 73.909 18.599 121.970 1.00 28.00 ? 460 ASP N O 1 ATOM 2999 C CB . ASP A 1 381 ? 70.536 18.279 121.286 1.00 15.25 ? 460 ASP N CB 1 ATOM 3000 C CG . ASP A 1 381 ? 71.052 16.910 120.874 1.00 11.01 ? 460 ASP N CG 1 ATOM 3001 O OD1 . ASP A 1 381 ? 71.109 15.969 121.754 1.00 11.35 ? 460 ASP N OD1 1 ATOM 3002 O OD2 . ASP A 1 381 ? 71.419 16.722 119.643 1.00 7.50 ? 460 ASP N OD2 1 ATOM 3003 N N . GLY A 1 382 ? 72.881 19.566 120.202 1.00 26.00 ? 461 GLY N N 1 ATOM 3004 C CA . GLY A 1 382 ? 74.110 19.745 119.452 1.00 30.40 ? 461 GLY N CA 1 ATOM 3005 C C . GLY A 1 382 ? 74.404 18.818 118.257 1.00 34.40 ? 461 GLY N C 1 ATOM 3006 O O . GLY A 1 382 ? 75.289 19.086 117.453 1.00 36.01 ? 461 GLY N O 1 ATOM 3007 N N . ALA A 1 383 ? 73.751 17.729 118.023 1.00 32.75 ? 462 ALA N N 1 ATOM 3008 C CA . ALA A 1 383 ? 74.206 16.898 116.883 1.00 28.95 ? 462 ALA N CA 1 ATOM 3009 C C . ALA A 1 383 ? 73.694 17.365 115.516 1.00 28.33 ? 462 ALA N C 1 ATOM 3010 O O . ALA A 1 383 ? 72.678 18.046 115.394 1.00 30.33 ? 462 ALA N O 1 ATOM 3011 C CB . ALA A 1 383 ? 73.724 15.479 117.066 1.00 32.71 ? 462 ALA N CB 1 ATOM 3012 N N . LYS A 1 384 ? 74.422 16.974 114.492 1.00 26.80 ? 463 LYS N N 1 ATOM 3013 C CA . LYS A 1 384 ? 74.055 17.301 113.104 1.00 28.13 ? 463 LYS N CA 1 ATOM 3014 C C . LYS A 1 384 ? 73.466 16.041 112.457 1.00 26.15 ? 463 LYS N C 1 ATOM 3015 O O . LYS A 1 384 ? 74.196 15.083 112.165 1.00 23.42 ? 463 LYS N O 1 ATOM 3016 C CB . LYS A 1 384 ? 75.307 17.792 112.320 1.00 29.83 ? 463 LYS N CB 1 ATOM 3017 C CG . LYS A 1 384 ? 76.257 18.620 113.210 1.00 31.67 ? 463 LYS N CG 1 ATOM 3018 C CD . LYS A 1 384 ? 76.389 20.159 112.932 1.00 35.13 ? 463 LYS N CD 1 ATOM 3019 C CE . LYS A 1 384 ? 75.295 20.905 113.791 1.00 37.62 ? 463 LYS N CE 1 ATOM 3020 N NZ . LYS A 1 384 ? 75.228 22.396 113.712 1.00 42.22 ? 463 LYS N NZ 1 ATOM 3021 N N . ILE A 1 385 ? 72.141 16.069 112.242 1.00 24.85 ? 464 ILE N N 1 ATOM 3022 C CA . ILE A 1 385 ? 71.427 14.905 111.675 1.00 24.62 ? 464 ILE N CA 1 ATOM 3023 C C . ILE A 1 385 ? 72.063 14.478 110.372 1.00 23.58 ? 464 ILE N C 1 ATOM 3024 O O . ILE A 1 385 ? 71.723 13.433 109.793 1.00 26.70 ? 464 ILE N O 1 ATOM 3025 C CB . ILE A 1 385 ? 69.929 15.184 111.481 1.00 25.46 ? 464 ILE N CB 1 ATOM 3026 C CG1 . ILE A 1 385 ? 69.122 14.786 112.716 1.00 25.65 ? 464 ILE N CG1 1 ATOM 3027 C CG2 . ILE A 1 385 ? 69.304 14.399 110.320 1.00 27.16 ? 464 ILE N CG2 1 ATOM 3028 C CD1 . ILE A 1 385 ? 69.099 13.268 112.940 1.00 24.07 ? 464 ILE N CD1 1 ATOM 3029 N N . GLU A 1 386 ? 73.003 15.246 109.901 1.00 20.79 ? 465 GLU N N 1 ATOM 3030 C CA . GLU A 1 386 ? 73.605 14.879 108.649 1.00 20.95 ? 465 GLU N CA 1 ATOM 3031 C C . GLU A 1 386 ? 74.835 14.034 108.825 1.00 22.06 ? 465 GLU N C 1 ATOM 3032 O O . GLU A 1 386 ? 75.426 13.534 107.861 1.00 21.88 ? 465 GLU N O 1 ATOM 3033 C CB . GLU A 1 386 ? 73.890 16.097 107.820 1.00 18.26 ? 465 GLU N CB 1 ATOM 3034 C CG . GLU A 1 386 ? 72.620 16.461 107.047 1.00 14.60 ? 465 GLU N CG 1 ATOM 3035 C CD . GLU A 1 386 ? 72.855 16.934 105.629 1.00 13.07 ? 465 GLU N CD 1 ATOM 3036 O OE1 . GLU A 1 386 ? 74.049 16.967 105.153 1.00 13.04 ? 465 GLU N OE1 1 ATOM 3037 O OE2 . GLU A 1 386 ? 71.851 17.302 104.908 1.00 11.64 ? 465 GLU N OE2 1 ATOM 3038 N N . TYR A 1 387 ? 75.299 13.800 109.992 1.00 21.69 ? 466 TYR N N 1 ATOM 3039 C CA . TYR A 1 387 ? 76.447 12.912 110.016 1.00 20.16 ? 466 TYR N CA 1 ATOM 3040 C C . TYR A 1 387 ? 76.033 11.479 110.310 1.00 21.23 ? 466 TYR N C 1 ATOM 3041 O O . TYR A 1 387 ? 76.848 10.604 110.578 1.00 20.86 ? 466 TYR N O 1 ATOM 3042 C CB . TYR A 1 387 ? 77.449 13.210 111.122 1.00 19.01 ? 466 TYR N CB 1 ATOM 3043 C CG . TYR A 1 387 ? 78.156 14.567 111.116 1.00 19.19 ? 466 TYR N CG 1 ATOM 3044 C CD1 . TYR A 1 387 ? 78.506 15.222 109.922 1.00 22.13 ? 466 TYR N CD1 1 ATOM 3045 C CD2 . TYR A 1 387 ? 78.464 15.147 112.348 1.00 20.67 ? 466 TYR N CD2 1 ATOM 3046 C CE1 . TYR A 1 387 ? 79.173 16.463 109.979 1.00 21.81 ? 466 TYR N CE1 1 ATOM 3047 C CE2 . TYR A 1 387 ? 79.126 16.378 112.402 1.00 19.63 ? 466 TYR N CE2 1 ATOM 3048 C CZ . TYR A 1 387 ? 79.483 17.037 111.223 1.00 21.02 ? 466 TYR N CZ 1 ATOM 3049 O OH . TYR A 1 387 ? 80.132 18.232 111.281 1.00 24.69 ? 466 TYR N OH 1 ATOM 3050 N N . PHE A 1 388 ? 74.813 11.207 110.289 1.00 22.49 ? 467 PHE N N 1 ATOM 3051 C CA . PHE A 1 388 ? 74.368 9.872 110.619 1.00 23.05 ? 467 PHE N CA 1 ATOM 3052 C C . PHE A 1 388 ? 73.858 9.155 109.402 1.00 27.95 ? 467 PHE N C 1 ATOM 3053 O O . PHE A 1 388 ? 73.336 8.051 109.533 1.00 29.04 ? 467 PHE N O 1 ATOM 3054 C CB . PHE A 1 388 ? 73.202 9.956 111.581 1.00 16.73 ? 467 PHE N CB 1 ATOM 3055 C CG . PHE A 1 388 ? 73.609 10.417 112.947 1.00 14.83 ? 467 PHE N CG 1 ATOM 3056 C CD1 . PHE A 1 388 ? 73.750 11.775 113.189 1.00 14.93 ? 467 PHE N CD1 1 ATOM 3057 C CD2 . PHE A 1 388 ? 73.840 9.475 113.938 1.00 11.20 ? 467 PHE N CD2 1 ATOM 3058 C CE1 . PHE A 1 388 ? 74.136 12.200 114.452 1.00 9.12 ? 467 PHE N CE1 1 ATOM 3059 C CE2 . PHE A 1 388 ? 74.223 9.895 115.198 1.00 8.45 ? 467 PHE N CE2 1 ATOM 3060 C CZ . PHE A 1 388 ? 74.373 11.258 115.458 1.00 7.90 ? 467 PHE N CZ 1 ATOM 3061 N N . LEU A 1 389 ? 74.015 9.870 108.282 1.00 31.62 ? 468 LEU N N 1 ATOM 3062 C CA . LEU A 1 389 ? 73.568 9.476 106.923 1.00 32.13 ? 468 LEU N CA 1 ATOM 3063 C C . LEU A 1 389 ? 74.750 8.938 106.116 1.00 36.14 ? 468 LEU N C 1 ATOM 3064 O O . LEU A 1 389 ? 74.350 8.033 105.427 1.00 40.78 ? 468 LEU N O 1 ATOM 3065 C CB . LEU A 1 389 ? 73.016 10.709 106.159 1.00 28.86 ? 468 LEU N CB 1 ATOM 3066 C CG . LEU A 1 389 ? 71.873 11.509 106.806 1.00 25.08 ? 468 LEU N CG 1 ATOM 3067 C CD1 . LEU A 1 389 ? 71.761 12.905 106.180 1.00 22.70 ? 468 LEU N CD1 1 ATOM 3068 C CD2 . LEU A 1 389 ? 70.503 10.841 106.639 1.00 24.40 ? 468 LEU N CD2 1 ATOM 3069 O OXT . LEU A 1 389 ? 75.714 9.665 106.244 1.00 40.55 ? 468 LEU N OXT 1 ATOM 3070 N N . ASP B 2 1 ? 57.004 12.372 100.943 1.00 26.22 ? 1 ASP L N 1 ATOM 3071 C CA . ASP B 2 1 ? 56.360 13.634 101.238 1.00 22.31 ? 1 ASP L CA 1 ATOM 3072 C C . ASP B 2 1 ? 54.903 13.262 101.438 1.00 22.24 ? 1 ASP L C 1 ATOM 3073 O O . ASP B 2 1 ? 54.415 12.311 100.818 1.00 23.65 ? 1 ASP L O 1 ATOM 3074 C CB . ASP B 2 1 ? 56.421 14.613 100.075 1.00 21.61 ? 1 ASP L CB 1 ATOM 3075 C CG . ASP B 2 1 ? 57.791 15.118 99.636 1.00 20.64 ? 1 ASP L CG 1 ATOM 3076 O OD1 . ASP B 2 1 ? 58.818 14.493 99.910 1.00 18.72 ? 1 ASP L OD1 1 ATOM 3077 O OD2 . ASP B 2 1 ? 57.826 16.169 98.995 1.00 22.11 ? 1 ASP L OD2 1 ATOM 3078 N N . ILE B 2 2 ? 54.253 14.047 102.280 1.00 20.90 ? 2 ILE L N 1 ATOM 3079 C CA . ILE B 2 2 ? 52.863 13.827 102.651 1.00 20.50 ? 2 ILE L CA 1 ATOM 3080 C C . ILE B 2 2 ? 52.193 14.652 101.569 1.00 21.43 ? 2 ILE L C 1 ATOM 3081 O O . ILE B 2 2 ? 52.790 15.630 101.092 1.00 21.55 ? 2 ILE L O 1 ATOM 3082 C CB . ILE B 2 2 ? 52.520 14.404 104.052 1.00 20.52 ? 2 ILE L CB 1 ATOM 3083 C CG1 . ILE B 2 2 ? 53.657 14.308 105.100 1.00 20.11 ? 2 ILE L CG1 1 ATOM 3084 C CG2 . ILE B 2 2 ? 51.345 13.599 104.528 1.00 21.73 ? 2 ILE L CG2 1 ATOM 3085 C CD1 . ILE B 2 2 ? 54.945 15.217 104.914 1.00 22.26 ? 2 ILE L CD1 1 ATOM 3086 N N . VAL B 2 3 ? 50.961 14.341 101.200 1.00 22.18 ? 3 VAL L N 1 ATOM 3087 C CA . VAL B 2 3 ? 50.303 14.930 100.049 1.00 22.70 ? 3 VAL L CA 1 ATOM 3088 C C . VAL B 2 3 ? 48.905 15.286 100.500 1.00 22.87 ? 3 VAL L C 1 ATOM 3089 O O . VAL B 2 3 ? 48.156 14.408 100.970 1.00 23.30 ? 3 VAL L O 1 ATOM 3090 C CB . VAL B 2 3 ? 50.277 13.890 98.942 1.00 22.66 ? 3 VAL L CB 1 ATOM 3091 C CG1 . VAL B 2 3 ? 49.437 14.406 97.788 1.00 20.64 ? 3 VAL L CG1 1 ATOM 3092 C CG2 . VAL B 2 3 ? 51.698 13.588 98.474 1.00 24.24 ? 3 VAL L CG2 1 ATOM 3093 N N . MET B 2 4 ? 48.665 16.599 100.419 1.00 22.31 ? 4 MET L N 1 ATOM 3094 C CA . MET B 2 4 ? 47.403 17.208 100.818 1.00 20.94 ? 4 MET L CA 1 ATOM 3095 C C . MET B 2 4 ? 46.624 17.410 99.551 1.00 21.84 ? 4 MET L C 1 ATOM 3096 O O . MET B 2 4 ? 47.108 17.994 98.570 1.00 21.31 ? 4 MET L O 1 ATOM 3097 C CB . MET B 2 4 ? 47.540 18.580 101.468 1.00 19.26 ? 4 MET L CB 1 ATOM 3098 C CG . MET B 2 4 ? 48.376 18.649 102.726 1.00 16.10 ? 4 MET L CG 1 ATOM 3099 S SD . MET B 2 4 ? 48.275 17.106 103.659 1.00 12.88 ? 4 MET L SD 1 ATOM 3100 C CE . MET B 2 4 ? 47.151 17.634 104.922 1.00 14.36 ? 4 MET L CE 1 ATOM 3101 N N . THR B 2 5 ? 45.387 16.956 99.596 1.00 23.52 ? 5 THR L N 1 ATOM 3102 C CA . THR B 2 5 ? 44.591 16.926 98.400 1.00 24.46 ? 5 THR L CA 1 ATOM 3103 C C . THR B 2 5 ? 43.350 17.746 98.790 1.00 24.93 ? 5 THR L C 1 ATOM 3104 O O . THR B 2 5 ? 42.741 17.575 99.859 1.00 25.38 ? 5 THR L O 1 ATOM 3105 C CB . THR B 2 5 ? 44.341 15.392 98.053 1.00 24.58 ? 5 THR L CB 1 ATOM 3106 O OG1 . THR B 2 5 ? 45.385 14.536 98.557 1.00 23.69 ? 5 THR L OG1 1 ATOM 3107 C CG2 . THR B 2 5 ? 44.350 15.217 96.552 1.00 24.16 ? 5 THR L CG2 1 ATOM 3108 N N . GLN B 2 6 ? 43.053 18.762 97.982 1.00 25.68 ? 6 GLN L N 1 ATOM 3109 C CA . GLN B 2 6 ? 41.898 19.601 98.236 1.00 26.96 ? 6 GLN L CA 1 ATOM 3110 C C . GLN B 2 6 ? 40.957 19.518 97.059 1.00 29.31 ? 6 GLN L C 1 ATOM 3111 O O . GLN B 2 6 ? 41.306 19.774 95.890 1.00 31.78 ? 6 GLN L O 1 ATOM 3112 C CB . GLN B 2 6 ? 42.307 21.029 98.415 1.00 23.55 ? 6 GLN L CB 1 ATOM 3113 C CG . GLN B 2 6 ? 42.310 21.344 99.879 1.00 22.37 ? 6 GLN L CG 1 ATOM 3114 C CD . GLN B 2 6 ? 42.838 22.724 100.146 1.00 21.73 ? 6 GLN L CD 1 ATOM 3115 O OE1 . GLN B 2 6 ? 44.054 22.957 100.180 1.00 19.90 ? 6 GLN L OE1 1 ATOM 3116 N NE2 . GLN B 2 6 ? 41.912 23.662 100.283 1.00 25.23 ? 6 GLN L NE2 1 ATOM 3117 N N . SER B 2 7 ? 39.766 19.085 97.396 1.00 31.22 ? 7 SER L N 1 ATOM 3118 C CA . SER B 2 7 ? 38.738 18.900 96.407 1.00 33.12 ? 7 SER L CA 1 ATOM 3119 C C . SER B 2 7 ? 37.476 19.072 97.228 1.00 34.17 ? 7 SER L C 1 ATOM 3120 O O . SER B 2 7 ? 37.344 18.415 98.286 1.00 36.33 ? 7 SER L O 1 ATOM 3121 C CB . SER B 2 7 ? 38.820 17.496 95.800 1.00 32.71 ? 7 SER L CB 1 ATOM 3122 O OG . SER B 2 7 ? 39.088 16.504 96.792 1.00 36.43 ? 7 SER L OG 1 ATOM 3123 N N . PRO B 2 8 ? 36.516 19.906 96.795 1.00 32.72 ? 8 PRO L N 1 ATOM 3124 C CA . PRO B 2 8 ? 36.641 20.704 95.573 1.00 31.88 ? 8 PRO L CA 1 ATOM 3125 C C . PRO B 2 8 ? 37.495 21.990 95.597 1.00 30.58 ? 8 PRO L C 1 ATOM 3126 O O . PRO B 2 8 ? 37.925 22.507 96.627 1.00 28.70 ? 8 PRO L O 1 ATOM 3127 C CB . PRO B 2 8 ? 35.153 20.898 95.200 1.00 31.77 ? 8 PRO L CB 1 ATOM 3128 C CG . PRO B 2 8 ? 34.402 19.760 95.880 1.00 30.97 ? 8 PRO L CG 1 ATOM 3129 C CD . PRO B 2 8 ? 35.108 19.805 97.227 1.00 30.79 ? 8 PRO L CD 1 ATOM 3130 N N . LYS B 2 9 ? 37.780 22.423 94.375 1.00 32.92 ? 9 LYS L N 1 ATOM 3131 C CA . LYS B 2 9 ? 38.524 23.628 94.050 1.00 34.72 ? 9 LYS L CA 1 ATOM 3132 C C . LYS B 2 9 ? 37.744 24.955 94.166 1.00 33.52 ? 9 LYS L C 1 ATOM 3133 O O . LYS B 2 9 ? 38.330 26.026 94.378 1.00 32.87 ? 9 LYS L O 1 ATOM 3134 C CB . LYS B 2 9 ? 39.064 23.469 92.622 1.00 38.54 ? 9 LYS L CB 1 ATOM 3135 C CG . LYS B 2 9 ? 40.302 24.306 92.263 1.00 41.61 ? 9 LYS L CG 1 ATOM 3136 C CD . LYS B 2 9 ? 40.621 24.246 90.770 1.00 44.65 ? 9 LYS L CD 1 ATOM 3137 C CE . LYS B 2 9 ? 41.952 24.932 90.478 1.00 46.35 ? 9 LYS L CE 1 ATOM 3138 N NZ . LYS B 2 9 ? 42.034 25.274 89.067 1.00 51.35 ? 9 LYS L NZ 1 ATOM 3139 N N . PHE B 2 10 ? 36.415 24.964 94.029 1.00 33.01 ? 10 PHE L N 1 ATOM 3140 C CA . PHE B 2 10 ? 35.622 26.180 94.113 1.00 33.37 ? 10 PHE L CA 1 ATOM 3141 C C . PHE B 2 10 ? 34.430 25.865 95.011 1.00 32.29 ? 10 PHE L C 1 ATOM 3142 O O . PHE B 2 10 ? 33.992 24.711 95.087 1.00 32.17 ? 10 PHE L O 1 ATOM 3143 C CB . PHE B 2 10 ? 35.261 26.499 92.694 1.00 36.21 ? 10 PHE L CB 1 ATOM 3144 C CG . PHE B 2 10 ? 34.219 27.572 92.458 1.00 40.11 ? 10 PHE L CG 1 ATOM 3145 C CD1 . PHE B 2 10 ? 34.610 28.904 92.368 1.00 41.85 ? 10 PHE L CD1 1 ATOM 3146 C CD2 . PHE B 2 10 ? 32.881 27.207 92.286 1.00 42.19 ? 10 PHE L CD2 1 ATOM 3147 C CE1 . PHE B 2 10 ? 33.656 29.878 92.093 1.00 43.51 ? 10 PHE L CE1 1 ATOM 3148 C CE2 . PHE B 2 10 ? 31.939 28.192 92.010 1.00 43.42 ? 10 PHE L CE2 1 ATOM 3149 C CZ . PHE B 2 10 ? 32.325 29.526 91.915 1.00 44.22 ? 10 PHE L CZ 1 ATOM 3150 N N . MET B 2 11 ? 33.933 26.852 95.742 1.00 30.81 ? 11 MET L N 1 ATOM 3151 C CA . MET B 2 11 ? 32.820 26.657 96.635 1.00 29.44 ? 11 MET L CA 1 ATOM 3152 C C . MET B 2 11 ? 31.964 27.891 96.617 1.00 29.24 ? 11 MET L C 1 ATOM 3153 O O . MET B 2 11 ? 32.477 29.002 96.650 1.00 29.36 ? 11 MET L O 1 ATOM 3154 C CB . MET B 2 11 ? 33.300 26.447 98.010 1.00 28.76 ? 11 MET L CB 1 ATOM 3155 C CG . MET B 2 11 ? 32.347 25.414 98.471 1.00 29.86 ? 11 MET L CG 1 ATOM 3156 S SD . MET B 2 11 ? 33.316 24.086 99.180 1.00 31.91 ? 11 MET L SD 1 ATOM 3157 C CE . MET B 2 11 ? 33.693 23.156 97.730 1.00 32.69 ? 11 MET L CE 1 ATOM 3158 N N . SER B 2 12 ? 30.672 27.764 96.546 1.00 29.53 ? 12 SER L N 1 ATOM 3159 C CA . SER B 2 12 ? 29.862 28.943 96.575 1.00 29.87 ? 12 SER L CA 1 ATOM 3160 C C . SER B 2 12 ? 28.923 28.685 97.722 1.00 29.76 ? 12 SER L C 1 ATOM 3161 O O . SER B 2 12 ? 28.449 27.545 97.870 1.00 31.50 ? 12 SER L O 1 ATOM 3162 C CB . SER B 2 12 ? 29.123 29.080 95.254 1.00 32.51 ? 12 SER L CB 1 ATOM 3163 O OG . SER B 2 12 ? 30.004 29.379 94.165 1.00 34.87 ? 12 SER L OG 1 ATOM 3164 N N . THR B 2 13 ? 28.744 29.725 98.545 1.00 27.58 ? 13 THR L N 1 ATOM 3165 C CA . THR B 2 13 ? 27.819 29.740 99.672 1.00 25.22 ? 13 THR L CA 1 ATOM 3166 C C . THR B 2 13 ? 27.265 31.137 99.731 1.00 24.63 ? 13 THR L C 1 ATOM 3167 O O . THR B 2 13 ? 27.865 32.081 99.232 1.00 24.80 ? 13 THR L O 1 ATOM 3168 C CB . THR B 2 13 ? 28.595 29.393 100.930 1.00 24.68 ? 13 THR L CB 1 ATOM 3169 O OG1 . THR B 2 13 ? 28.562 27.980 100.893 1.00 23.97 ? 13 THR L OG1 1 ATOM 3170 C CG2 . THR B 2 13 ? 28.100 29.990 102.245 1.00 24.56 ? 13 THR L CG2 1 ATOM 3171 N N . SER B 2 14 ? 26.089 31.275 100.274 1.00 23.77 ? 14 SER L N 1 ATOM 3172 C CA . SER B 2 14 ? 25.431 32.550 100.440 1.00 21.57 ? 14 SER L CA 1 ATOM 3173 C C . SER B 2 14 ? 25.815 33.255 101.740 1.00 19.67 ? 14 SER L C 1 ATOM 3174 O O . SER B 2 14 ? 26.295 32.624 102.687 1.00 18.18 ? 14 SER L O 1 ATOM 3175 C CB . SER B 2 14 ? 23.964 32.226 100.340 1.00 21.67 ? 14 SER L CB 1 ATOM 3176 O OG . SER B 2 14 ? 23.698 30.908 100.866 1.00 23.97 ? 14 SER L OG 1 ATOM 3177 N N . VAL B 2 15 ? 25.540 34.552 101.841 1.00 18.87 ? 15 VAL L N 1 ATOM 3178 C CA . VAL B 2 15 ? 25.996 35.407 102.937 1.00 18.90 ? 15 VAL L CA 1 ATOM 3179 C C . VAL B 2 15 ? 25.245 35.048 104.187 1.00 20.44 ? 15 VAL L C 1 ATOM 3180 O O . VAL B 2 15 ? 24.033 35.164 104.213 1.00 19.66 ? 15 VAL L O 1 ATOM 3181 C CB . VAL B 2 15 ? 25.771 36.888 102.479 1.00 18.43 ? 15 VAL L CB 1 ATOM 3182 C CG1 . VAL B 2 15 ? 25.789 37.914 103.591 1.00 15.66 ? 15 VAL L CG1 1 ATOM 3183 C CG2 . VAL B 2 15 ? 26.920 37.245 101.588 1.00 18.33 ? 15 VAL L CG2 1 ATOM 3184 N N . GLY B 2 16 ? 25.880 34.558 105.220 1.00 22.02 ? 16 GLY L N 1 ATOM 3185 C CA . GLY B 2 16 ? 25.131 34.199 106.402 1.00 23.77 ? 16 GLY L CA 1 ATOM 3186 C C . GLY B 2 16 ? 25.081 32.696 106.567 1.00 25.09 ? 16 GLY L C 1 ATOM 3187 O O . GLY B 2 16 ? 24.831 32.191 107.663 1.00 28.96 ? 16 GLY L O 1 ATOM 3188 N N . ASP B 2 17 ? 25.408 31.951 105.538 1.00 25.90 ? 17 ASP L N 1 ATOM 3189 C CA . ASP B 2 17 ? 25.394 30.522 105.639 1.00 28.47 ? 17 ASP L CA 1 ATOM 3190 C C . ASP B 2 17 ? 26.710 29.894 106.021 1.00 28.69 ? 17 ASP L C 1 ATOM 3191 O O . ASP B 2 17 ? 27.626 30.604 106.456 1.00 28.38 ? 17 ASP L O 1 ATOM 3192 C CB . ASP B 2 17 ? 24.912 29.978 104.332 1.00 30.87 ? 17 ASP L CB 1 ATOM 3193 C CG . ASP B 2 17 ? 23.403 29.833 104.416 1.00 33.91 ? 17 ASP L CG 1 ATOM 3194 O OD1 . ASP B 2 17 ? 22.939 28.992 105.211 1.00 36.00 ? 17 ASP L OD1 1 ATOM 3195 O OD2 . ASP B 2 17 ? 22.706 30.571 103.708 1.00 35.86 ? 17 ASP L OD2 1 ATOM 3196 N N . ARG B 2 18 ? 26.704 28.553 105.925 1.00 29.25 ? 18 ARG L N 1 ATOM 3197 C CA . ARG B 2 18 ? 27.817 27.669 106.217 1.00 30.40 ? 18 ARG L CA 1 ATOM 3198 C C . ARG B 2 18 ? 28.478 27.220 104.937 1.00 27.44 ? 18 ARG L C 1 ATOM 3199 O O . ARG B 2 18 ? 27.812 27.046 103.917 1.00 26.51 ? 18 ARG L O 1 ATOM 3200 C CB . ARG B 2 18 ? 27.393 26.389 106.904 1.00 36.85 ? 18 ARG L CB 1 ATOM 3201 C CG . ARG B 2 18 ? 26.877 26.695 108.266 1.00 44.23 ? 18 ARG L CG 1 ATOM 3202 C CD . ARG B 2 18 ? 26.561 25.467 109.067 1.00 50.38 ? 18 ARG L CD 1 ATOM 3203 N NE . ARG B 2 18 ? 26.367 25.955 110.426 1.00 57.02 ? 18 ARG L NE 1 ATOM 3204 C CZ . ARG B 2 18 ? 26.596 25.220 111.515 1.00 61.19 ? 18 ARG L CZ 1 ATOM 3205 N NH1 . ARG B 2 18 ? 26.955 23.937 111.416 1.00 63.37 ? 18 ARG L NH1 1 ATOM 3206 N NH2 . ARG B 2 18 ? 26.444 25.779 112.722 1.00 64.38 ? 18 ARG L NH2 1 ATOM 3207 N N . VAL B 2 19 ? 29.774 27.001 104.977 1.00 23.20 ? 19 VAL L N 1 ATOM 3208 C CA . VAL B 2 19 ? 30.531 26.374 103.910 1.00 18.29 ? 19 VAL L CA 1 ATOM 3209 C C . VAL B 2 19 ? 31.506 25.504 104.688 1.00 17.34 ? 19 VAL L C 1 ATOM 3210 O O . VAL B 2 19 ? 31.690 25.638 105.912 1.00 16.91 ? 19 VAL L O 1 ATOM 3211 C CB . VAL B 2 19 ? 31.290 27.404 103.053 1.00 16.73 ? 19 VAL L CB 1 ATOM 3212 C CG1 . VAL B 2 19 ? 32.302 28.179 103.870 1.00 17.48 ? 19 VAL L CG1 1 ATOM 3213 C CG2 . VAL B 2 19 ? 31.984 26.660 101.919 1.00 16.78 ? 19 VAL L CG2 1 ATOM 3214 N N . THR B 2 20 ? 32.131 24.556 104.047 1.00 15.85 ? 20 THR L N 1 ATOM 3215 C CA . THR B 2 20 ? 33.066 23.735 104.741 1.00 15.19 ? 20 THR L CA 1 ATOM 3216 C C . THR B 2 20 ? 34.069 23.382 103.668 1.00 15.19 ? 20 THR L C 1 ATOM 3217 O O . THR B 2 20 ? 33.727 23.303 102.481 1.00 17.62 ? 20 THR L O 1 ATOM 3218 C CB . THR B 2 20 ? 32.199 22.642 105.298 1.00 14.79 ? 20 THR L CB 1 ATOM 3219 O OG1 . THR B 2 20 ? 33.069 22.048 106.208 1.00 17.23 ? 20 THR L OG1 1 ATOM 3220 C CG2 . THR B 2 20 ? 31.571 21.712 104.303 1.00 13.84 ? 20 THR L CG2 1 ATOM 3221 N N . ILE B 2 21 ? 35.332 23.390 104.011 1.00 14.12 ? 21 ILE L N 1 ATOM 3222 C CA . ILE B 2 21 ? 36.324 23.097 103.014 1.00 14.88 ? 21 ILE L CA 1 ATOM 3223 C C . ILE B 2 21 ? 36.974 21.804 103.432 1.00 17.32 ? 21 ILE L C 1 ATOM 3224 O O . ILE B 2 21 ? 37.370 21.670 104.590 1.00 20.27 ? 21 ILE L O 1 ATOM 3225 C CB . ILE B 2 21 ? 37.329 24.274 102.926 1.00 14.32 ? 21 ILE L CB 1 ATOM 3226 C CG1 . ILE B 2 21 ? 36.751 25.428 102.106 1.00 13.85 ? 21 ILE L CG1 1 ATOM 3227 C CG2 . ILE B 2 21 ? 38.589 23.803 102.219 1.00 13.63 ? 21 ILE L CG2 1 ATOM 3228 C CD1 . ILE B 2 21 ? 35.876 26.446 102.844 1.00 14.78 ? 21 ILE L CD1 1 ATOM 3229 N N . THR B 2 22 ? 37.084 20.831 102.543 1.00 18.91 ? 22 THR L N 1 ATOM 3230 C CA . THR B 2 22 ? 37.667 19.540 102.872 1.00 20.04 ? 22 THR L CA 1 ATOM 3231 C C . THR B 2 22 ? 39.107 19.413 102.389 1.00 19.85 ? 22 THR L C 1 ATOM 3232 O O . THR B 2 22 ? 39.424 19.704 101.221 1.00 22.35 ? 22 THR L O 1 ATOM 3233 C CB . THR B 2 22 ? 36.821 18.388 102.244 1.00 21.83 ? 22 THR L CB 1 ATOM 3234 O OG1 . THR B 2 22 ? 35.496 18.881 101.962 1.00 24.15 ? 22 THR L OG1 1 ATOM 3235 C CG2 . THR B 2 22 ? 36.787 17.176 103.195 1.00 23.32 ? 22 THR L CG2 1 ATOM 3236 N N . CYS B 2 23 ? 39.940 18.922 103.322 1.00 18.39 ? 23 CYS L N 1 ATOM 3237 C CA . CYS B 2 23 ? 41.347 18.648 103.051 1.00 16.33 ? 23 CYS L CA 1 ATOM 3238 C C . CYS B 2 23 ? 41.658 17.223 103.478 1.00 15.79 ? 23 CYS L C 1 ATOM 3239 O O . CYS B 2 23 ? 41.067 16.690 104.436 1.00 13.75 ? 23 CYS L O 1 ATOM 3240 C CB . CYS B 2 23 ? 42.217 19.563 103.828 1.00 12.48 ? 23 CYS L CB 1 ATOM 3241 S SG . CYS B 2 23 ? 44.009 19.374 103.585 1.00 9.07 ? 23 CYS L SG 1 ATOM 3242 N N . LYS B 2 24 ? 42.587 16.612 102.750 1.00 17.89 ? 24 LYS L N 1 ATOM 3243 C CA . LYS B 2 24 ? 42.986 15.260 103.068 1.00 19.92 ? 24 LYS L CA 1 ATOM 3244 C C . LYS B 2 24 ? 44.441 14.992 102.688 1.00 19.09 ? 24 LYS L C 1 ATOM 3245 O O . LYS B 2 24 ? 44.967 15.415 101.663 1.00 16.40 ? 24 LYS L O 1 ATOM 3246 C CB . LYS B 2 24 ? 42.020 14.246 102.374 1.00 23.91 ? 24 LYS L CB 1 ATOM 3247 C CG . LYS B 2 24 ? 42.510 13.482 101.150 1.00 28.29 ? 24 LYS L CG 1 ATOM 3248 C CD . LYS B 2 24 ? 41.592 12.314 100.785 1.00 32.34 ? 24 LYS L CD 1 ATOM 3249 C CE . LYS B 2 24 ? 42.043 11.655 99.450 1.00 34.35 ? 24 LYS L CE 1 ATOM 3250 N NZ . LYS B 2 24 ? 43.320 10.945 99.538 1.00 35.36 ? 24 LYS L NZ 1 ATOM 3251 N N . ALA B 2 25 ? 45.079 14.292 103.608 1.00 19.58 ? 25 ALA L N 1 ATOM 3252 C CA . ALA B 2 25 ? 46.476 13.908 103.531 1.00 20.97 ? 25 ALA L CA 1 ATOM 3253 C C . ALA B 2 25 ? 46.567 12.466 103.046 1.00 21.75 ? 25 ALA L C 1 ATOM 3254 O O . ALA B 2 25 ? 45.579 11.704 103.102 1.00 20.89 ? 25 ALA L O 1 ATOM 3255 C CB . ALA B 2 25 ? 47.165 13.951 104.902 1.00 20.69 ? 25 ALA L CB 1 ATOM 3256 N N . SER B 2 26 ? 47.771 12.104 102.591 1.00 22.09 ? 26 SER L N 1 ATOM 3257 C CA . SER B 2 26 ? 48.044 10.744 102.182 1.00 23.92 ? 26 SER L CA 1 ATOM 3258 C C . SER B 2 26 ? 48.526 9.733 103.239 1.00 25.28 ? 26 SER L C 1 ATOM 3259 O O . SER B 2 26 ? 49.075 8.672 102.914 1.00 25.52 ? 26 SER L O 1 ATOM 3260 C CB . SER B 2 26 ? 49.017 10.855 101.027 1.00 24.45 ? 26 SER L CB 1 ATOM 3261 O OG . SER B 2 26 ? 50.137 11.667 101.342 1.00 29.08 ? 26 SER L OG 1 ATOM 3262 N N . GLN B 2 27 ? 48.404 10.045 104.530 1.00 28.50 ? 27 GLN L N 1 ATOM 3263 C CA . GLN B 2 27 ? 48.625 9.112 105.640 1.00 30.85 ? 27 GLN L CA 1 ATOM 3264 C C . GLN B 2 27 ? 48.200 9.853 106.886 1.00 31.85 ? 27 GLN L C 1 ATOM 3265 O O . GLN B 2 27 ? 48.045 11.076 106.790 1.00 33.98 ? 27 GLN L O 1 ATOM 3266 C CB . GLN B 2 27 ? 50.066 8.721 105.859 1.00 31.84 ? 27 GLN L CB 1 ATOM 3267 C CG . GLN B 2 27 ? 50.988 9.875 106.159 1.00 34.36 ? 27 GLN L CG 1 ATOM 3268 C CD . GLN B 2 27 ? 52.173 9.918 105.225 1.00 36.98 ? 27 GLN L CD 1 ATOM 3269 O OE1 . GLN B 2 27 ? 52.934 10.888 105.263 1.00 39.63 ? 27 GLN L OE1 1 ATOM 3270 N NE2 . GLN B 2 27 ? 52.378 8.939 104.330 1.00 37.70 ? 27 GLN L NE2 1 ATOM 3271 N N . ASP B 2 28 ? 47.948 9.152 108.000 1.00 30.60 ? 28 ASP L N 1 ATOM 3272 C CA . ASP B 2 28 ? 47.589 9.804 109.259 1.00 28.59 ? 28 ASP L CA 1 ATOM 3273 C C . ASP B 2 28 ? 48.693 10.786 109.628 1.00 27.59 ? 28 ASP L C 1 ATOM 3274 O O . ASP B 2 28 ? 49.832 10.420 109.913 1.00 27.94 ? 28 ASP L O 1 ATOM 3275 C CB . ASP B 2 28 ? 47.399 8.754 110.379 1.00 31.74 ? 28 ASP L CB 1 ATOM 3276 C CG . ASP B 2 28 ? 47.073 9.272 111.793 1.00 35.33 ? 28 ASP L CG 1 ATOM 3277 O OD1 . ASP B 2 28 ? 46.483 10.346 111.967 1.00 37.48 ? 28 ASP L OD1 1 ATOM 3278 O OD2 . ASP B 2 28 ? 47.402 8.579 112.755 1.00 36.76 ? 28 ASP L OD2 1 ATOM 3279 N N . VAL B 2 29 ? 48.285 12.050 109.571 1.00 26.14 ? 29 VAL L N 1 ATOM 3280 C CA . VAL B 2 29 ? 49.140 13.190 109.853 1.00 25.58 ? 29 VAL L CA 1 ATOM 3281 C C . VAL B 2 29 ? 48.897 13.685 111.293 1.00 25.34 ? 29 VAL L C 1 ATOM 3282 O O . VAL B 2 29 ? 49.302 14.747 111.775 1.00 28.20 ? 29 VAL L O 1 ATOM 3283 C CB . VAL B 2 29 ? 48.795 14.147 108.678 1.00 25.56 ? 29 VAL L CB 1 ATOM 3284 C CG1 . VAL B 2 29 ? 48.428 15.558 109.075 1.00 25.27 ? 29 VAL L CG1 1 ATOM 3285 C CG2 . VAL B 2 29 ? 50.022 14.153 107.811 1.00 26.85 ? 29 VAL L CG2 1 ATOM 3286 N N . SER B 2 30 ? 48.270 12.805 112.058 1.00 23.40 ? 30 SER L N 1 ATOM 3287 C CA . SER B 2 30 ? 47.970 13.022 113.460 1.00 23.17 ? 30 SER L CA 1 ATOM 3288 C C . SER B 2 30 ? 47.587 14.430 113.950 1.00 22.47 ? 30 SER L C 1 ATOM 3289 O O . SER B 2 30 ? 48.047 14.954 114.978 1.00 26.26 ? 30 SER L O 1 ATOM 3290 C CB . SER B 2 30 ? 49.167 12.465 114.265 1.00 22.09 ? 30 SER L CB 1 ATOM 3291 O OG . SER B 2 30 ? 48.771 12.144 115.593 1.00 25.41 ? 30 SER L OG 1 ATOM 3292 N N . THR B 2 31 ? 46.635 14.961 113.168 1.00 21.06 ? 31 THR L N 1 ATOM 3293 C CA . THR B 2 31 ? 46.003 16.245 113.415 1.00 17.41 ? 31 THR L CA 1 ATOM 3294 C C . THR B 2 31 ? 46.878 17.470 113.175 1.00 13.46 ? 31 THR L C 1 ATOM 3295 O O . THR B 2 31 ? 46.413 18.609 113.253 1.00 12.55 ? 31 THR L O 1 ATOM 3296 C CB . THR B 2 31 ? 45.431 16.076 114.860 1.00 17.53 ? 31 THR L CB 1 ATOM 3297 O OG1 . THR B 2 31 ? 44.333 15.181 114.676 1.00 18.77 ? 31 THR L OG1 1 ATOM 3298 C CG2 . THR B 2 31 ? 45.073 17.328 115.581 1.00 18.05 ? 31 THR L CG2 1 ATOM 3299 N N . ALA B 2 32 ? 48.132 17.332 112.770 1.00 11.89 ? 32 ALA L N 1 ATOM 3300 C CA . ALA B 2 32 ? 48.994 18.472 112.509 1.00 10.53 ? 32 ALA L CA 1 ATOM 3301 C C . ALA B 2 32 ? 48.593 19.103 111.165 1.00 9.55 ? 32 ALA L C 1 ATOM 3302 O O . ALA B 2 32 ? 49.235 18.911 110.136 1.00 9.62 ? 32 ALA L O 1 ATOM 3303 C CB . ALA B 2 32 ? 50.441 17.957 112.508 1.00 10.38 ? 32 ALA L CB 1 ATOM 3304 N N . VAL B 2 33 ? 47.471 19.841 111.152 1.00 6.24 ? 33 VAL L N 1 ATOM 3305 C CA . VAL B 2 33 ? 46.909 20.562 110.004 1.00 6.69 ? 33 VAL L CA 1 ATOM 3306 C C . VAL B 2 33 ? 46.720 22.050 110.354 1.00 6.92 ? 33 VAL L C 1 ATOM 3307 O O . VAL B 2 33 ? 46.263 22.437 111.442 1.00 10.05 ? 33 VAL L O 1 ATOM 3308 C CB . VAL B 2 33 ? 45.575 19.917 109.623 1.00 5.26 ? 33 VAL L CB 1 ATOM 3309 C CG1 . VAL B 2 33 ? 44.784 20.775 108.655 1.00 6.36 ? 33 VAL L CG1 1 ATOM 3310 C CG2 . VAL B 2 33 ? 45.868 18.609 108.937 1.00 2.04 ? 33 VAL L CG2 1 ATOM 3311 N N . VAL B 2 34 ? 47.159 22.903 109.434 1.00 6.22 ? 34 VAL L N 1 ATOM 3312 C CA . VAL B 2 34 ? 47.119 24.357 109.555 1.00 6.44 ? 34 VAL L CA 1 ATOM 3313 C C . VAL B 2 34 ? 46.213 24.728 108.384 1.00 7.30 ? 34 VAL L C 1 ATOM 3314 O O . VAL B 2 34 ? 46.261 24.054 107.331 1.00 8.24 ? 34 VAL L O 1 ATOM 3315 C CB . VAL B 2 34 ? 48.469 25.056 109.255 1.00 7.05 ? 34 VAL L CB 1 ATOM 3316 C CG1 . VAL B 2 34 ? 48.336 26.549 109.472 1.00 5.87 ? 34 VAL L CG1 1 ATOM 3317 C CG2 . VAL B 2 34 ? 49.562 24.522 110.117 1.00 8.67 ? 34 VAL L CG2 1 ATOM 3318 N N . TRP B 2 35 ? 45.449 25.823 108.530 1.00 5.62 ? 35 TRP L N 1 ATOM 3319 C CA . TRP B 2 35 ? 44.644 26.374 107.444 1.00 4.42 ? 35 TRP L CA 1 ATOM 3320 C C . TRP B 2 35 ? 45.036 27.819 107.167 1.00 5.14 ? 35 TRP L C 1 ATOM 3321 O O . TRP B 2 35 ? 45.050 28.618 108.101 1.00 5.61 ? 35 TRP L O 1 ATOM 3322 C CB . TRP B 2 35 ? 43.128 26.314 107.783 1.00 3.76 ? 35 TRP L CB 1 ATOM 3323 C CG . TRP B 2 35 ? 42.513 24.911 107.646 1.00 5.03 ? 35 TRP L CG 1 ATOM 3324 C CD1 . TRP B 2 35 ? 42.290 24.138 108.751 1.00 6.06 ? 35 TRP L CD1 1 ATOM 3325 C CD2 . TRP B 2 35 ? 42.139 24.269 106.483 1.00 5.03 ? 35 TRP L CD2 1 ATOM 3326 N NE1 . TRP B 2 35 ? 41.799 23.028 108.289 1.00 5.80 ? 35 TRP L NE1 1 ATOM 3327 C CE2 . TRP B 2 35 ? 41.697 23.050 106.972 1.00 4.07 ? 35 TRP L CE2 1 ATOM 3328 C CE3 . TRP B 2 35 ? 42.154 24.544 105.126 1.00 4.04 ? 35 TRP L CE3 1 ATOM 3329 C CZ2 . TRP B 2 35 ? 41.210 22.094 106.151 1.00 2.04 ? 35 TRP L CZ2 1 ATOM 3330 C CZ3 . TRP B 2 35 ? 41.669 23.577 104.298 1.00 3.21 ? 35 TRP L CZ3 1 ATOM 3331 C CH2 . TRP B 2 35 ? 41.229 22.383 104.813 1.00 3.08 ? 35 TRP L CH2 1 ATOM 3332 N N . TYR B 2 36 ? 45.457 28.229 105.979 1.00 5.67 ? 36 TYR L N 1 ATOM 3333 C CA . TYR B 2 36 ? 45.657 29.641 105.714 1.00 5.62 ? 36 TYR L CA 1 ATOM 3334 C C . TYR B 2 36 ? 44.497 30.064 104.803 1.00 8.50 ? 36 TYR L C 1 ATOM 3335 O O . TYR B 2 36 ? 43.808 29.295 104.115 1.00 11.82 ? 36 TYR L O 1 ATOM 3336 C CB . TYR B 2 36 ? 46.992 29.918 104.988 1.00 3.28 ? 36 TYR L CB 1 ATOM 3337 C CG . TYR B 2 36 ? 48.255 29.438 105.660 1.00 4.54 ? 36 TYR L CG 1 ATOM 3338 C CD1 . TYR B 2 36 ? 48.943 30.225 106.548 1.00 6.54 ? 36 TYR L CD1 1 ATOM 3339 C CD2 . TYR B 2 36 ? 48.689 28.165 105.372 1.00 4.61 ? 36 TYR L CD2 1 ATOM 3340 C CE1 . TYR B 2 36 ? 50.052 29.687 107.162 1.00 7.07 ? 36 TYR L CE1 1 ATOM 3341 C CE2 . TYR B 2 36 ? 49.806 27.624 105.984 1.00 6.48 ? 36 TYR L CE2 1 ATOM 3342 C CZ . TYR B 2 36 ? 50.494 28.391 106.880 1.00 6.68 ? 36 TYR L CZ 1 ATOM 3343 O OH . TYR B 2 36 ? 51.595 27.847 107.540 1.00 10.36 ? 36 TYR L OH 1 ATOM 3344 N N . GLN B 2 37 ? 44.359 31.371 104.797 1.00 8.93 ? 37 GLN L N 1 ATOM 3345 C CA . GLN B 2 37 ? 43.375 32.070 104.021 1.00 10.26 ? 37 GLN L CA 1 ATOM 3346 C C . GLN B 2 37 ? 44.180 33.051 103.201 1.00 13.47 ? 37 GLN L C 1 ATOM 3347 O O . GLN B 2 37 ? 45.035 33.729 103.765 1.00 15.56 ? 37 GLN L O 1 ATOM 3348 C CB . GLN B 2 37 ? 42.467 32.811 104.944 1.00 8.70 ? 37 GLN L CB 1 ATOM 3349 C CG . GLN B 2 37 ? 41.373 33.630 104.316 1.00 8.80 ? 37 GLN L CG 1 ATOM 3350 C CD . GLN B 2 37 ? 40.841 34.698 105.239 1.00 10.27 ? 37 GLN L CD 1 ATOM 3351 O OE1 . GLN B 2 37 ? 41.601 35.597 105.628 1.00 7.45 ? 37 GLN L OE1 1 ATOM 3352 N NE2 . GLN B 2 37 ? 39.560 34.650 105.602 1.00 10.72 ? 37 GLN L NE2 1 ATOM 3353 N N . GLN B 2 38 ? 44.006 33.153 101.899 1.00 13.62 ? 38 GLN L N 1 ATOM 3354 C CA . GLN B 2 38 ? 44.720 34.153 101.152 1.00 15.11 ? 38 GLN L CA 1 ATOM 3355 C C . GLN B 2 38 ? 43.675 35.029 100.507 1.00 17.63 ? 38 GLN L C 1 ATOM 3356 O O . GLN B 2 38 ? 42.917 34.613 99.612 1.00 13.90 ? 38 GLN L O 1 ATOM 3357 C CB . GLN B 2 38 ? 45.576 33.537 100.081 1.00 15.29 ? 38 GLN L CB 1 ATOM 3358 C CG . GLN B 2 38 ? 46.435 34.637 99.474 1.00 15.69 ? 38 GLN L CG 1 ATOM 3359 C CD . GLN B 2 38 ? 47.516 34.109 98.562 1.00 16.27 ? 38 GLN L CD 1 ATOM 3360 O OE1 . GLN B 2 38 ? 47.437 33.020 97.985 1.00 16.49 ? 38 GLN L OE1 1 ATOM 3361 N NE2 . GLN B 2 38 ? 48.592 34.872 98.421 1.00 16.68 ? 38 GLN L NE2 1 ATOM 3362 N N . LYS B 2 39 ? 43.632 36.244 101.043 1.00 22.38 ? 39 LYS L N 1 ATOM 3363 C CA . LYS B 2 39 ? 42.689 37.270 100.585 1.00 23.94 ? 39 LYS L CA 1 ATOM 3364 C C . LYS B 2 39 ? 43.140 37.789 99.210 1.00 24.84 ? 39 LYS L C 1 ATOM 3365 O O . LYS B 2 39 ? 44.351 37.834 98.946 1.00 23.04 ? 39 LYS L O 1 ATOM 3366 C CB . LYS B 2 39 ? 42.688 38.367 101.643 1.00 23.94 ? 39 LYS L CB 1 ATOM 3367 C CG . LYS B 2 39 ? 41.348 38.945 102.031 1.00 23.28 ? 39 LYS L CG 1 ATOM 3368 C CD . LYS B 2 39 ? 40.671 38.139 103.134 1.00 22.17 ? 39 LYS L CD 1 ATOM 3369 C CE . LYS B 2 39 ? 39.721 39.118 103.847 1.00 23.23 ? 39 LYS L CE 1 ATOM 3370 N NZ . LYS B 2 39 ? 38.762 38.487 104.745 1.00 25.09 ? 39 LYS L NZ 1 ATOM 3371 N N . PRO B 2 40 ? 42.286 38.162 98.246 1.00 26.77 ? 40 PRO L N 1 ATOM 3372 C CA . PRO B 2 40 ? 42.717 38.382 96.860 1.00 27.63 ? 40 PRO L CA 1 ATOM 3373 C C . PRO B 2 40 ? 43.545 39.659 96.849 1.00 27.49 ? 40 PRO L C 1 ATOM 3374 O O . PRO B 2 40 ? 43.204 40.711 97.402 1.00 25.82 ? 40 PRO L O 1 ATOM 3375 C CB . PRO B 2 40 ? 41.416 38.411 96.069 1.00 27.64 ? 40 PRO L CB 1 ATOM 3376 C CG . PRO B 2 40 ? 40.414 38.983 97.048 1.00 27.33 ? 40 PRO L CG 1 ATOM 3377 C CD . PRO B 2 40 ? 40.849 38.405 98.417 1.00 27.64 ? 40 PRO L CD 1 ATOM 3378 N N . GLY B 2 41 ? 44.751 39.318 96.386 1.00 28.78 ? 41 GLY L N 1 ATOM 3379 C CA . GLY B 2 41 ? 45.863 40.242 96.290 1.00 28.27 ? 41 GLY L CA 1 ATOM 3380 C C . GLY B 2 41 ? 46.354 40.611 97.684 1.00 27.81 ? 41 GLY L C 1 ATOM 3381 O O . GLY B 2 41 ? 46.430 41.789 98.052 1.00 28.49 ? 41 GLY L O 1 ATOM 3382 N N . GLN B 2 42 ? 46.642 39.593 98.498 1.00 26.93 ? 42 GLN L N 1 ATOM 3383 C CA . GLN B 2 42 ? 47.158 39.766 99.850 1.00 24.30 ? 42 GLN L CA 1 ATOM 3384 C C . GLN B 2 42 ? 47.946 38.518 100.145 1.00 21.91 ? 42 GLN L C 1 ATOM 3385 O O . GLN B 2 42 ? 47.998 37.552 99.365 1.00 20.11 ? 42 GLN L O 1 ATOM 3386 C CB . GLN B 2 42 ? 46.034 39.883 100.858 1.00 27.97 ? 42 GLN L CB 1 ATOM 3387 C CG . GLN B 2 42 ? 45.539 41.302 101.032 1.00 32.39 ? 42 GLN L CG 1 ATOM 3388 C CD . GLN B 2 42 ? 44.322 41.433 101.932 1.00 35.83 ? 42 GLN L CD 1 ATOM 3389 O OE1 . GLN B 2 42 ? 44.238 40.976 103.073 1.00 39.60 ? 42 GLN L OE1 1 ATOM 3390 N NE2 . GLN B 2 42 ? 43.293 42.051 101.390 1.00 37.07 ? 42 GLN L NE2 1 ATOM 3391 N N . SER B 2 43 ? 48.560 38.546 101.303 1.00 20.25 ? 43 SER L N 1 ATOM 3392 C CA . SER B 2 43 ? 49.345 37.425 101.780 1.00 19.21 ? 43 SER L CA 1 ATOM 3393 C C . SER B 2 43 ? 48.413 36.502 102.563 1.00 16.75 ? 43 SER L C 1 ATOM 3394 O O . SER B 2 43 ? 47.325 36.937 102.985 1.00 16.36 ? 43 SER L O 1 ATOM 3395 C CB . SER B 2 43 ? 50.446 37.982 102.655 1.00 20.25 ? 43 SER L CB 1 ATOM 3396 O OG . SER B 2 43 ? 51.042 39.076 101.961 1.00 21.54 ? 43 SER L OG 1 ATOM 3397 N N . PRO B 2 44 ? 48.764 35.234 102.751 1.00 13.10 ? 44 PRO L N 1 ATOM 3398 C CA . PRO B 2 44 ? 48.054 34.366 103.666 1.00 10.31 ? 44 PRO L CA 1 ATOM 3399 C C . PRO B 2 44 ? 48.125 34.793 105.141 1.00 12.54 ? 44 PRO L C 1 ATOM 3400 O O . PRO B 2 44 ? 49.121 35.355 105.642 1.00 12.68 ? 44 PRO L O 1 ATOM 3401 C CB . PRO B 2 44 ? 48.645 33.009 103.429 1.00 8.40 ? 44 PRO L CB 1 ATOM 3402 C CG . PRO B 2 44 ? 49.364 33.147 102.135 1.00 6.97 ? 44 PRO L CG 1 ATOM 3403 C CD . PRO B 2 44 ? 49.876 34.562 102.134 1.00 10.16 ? 44 PRO L CD 1 ATOM 3404 N N . LYS B 2 45 ? 47.029 34.494 105.837 1.00 12.95 ? 45 LYS L N 1 ATOM 3405 C CA . LYS B 2 45 ? 46.857 34.673 107.263 1.00 11.10 ? 45 LYS L CA 1 ATOM 3406 C C . LYS B 2 45 ? 46.610 33.219 107.697 1.00 10.98 ? 45 LYS L C 1 ATOM 3407 O O . LYS B 2 45 ? 45.929 32.406 107.044 1.00 9.97 ? 45 LYS L O 1 ATOM 3408 C CB . LYS B 2 45 ? 45.625 35.559 107.519 1.00 11.86 ? 45 LYS L CB 1 ATOM 3409 C CG . LYS B 2 45 ? 45.336 35.931 108.977 1.00 11.71 ? 45 LYS L CG 1 ATOM 3410 C CD . LYS B 2 45 ? 44.139 36.879 109.125 1.00 11.94 ? 45 LYS L CD 1 ATOM 3411 C CE . LYS B 2 45 ? 43.871 37.165 110.608 1.00 12.12 ? 45 LYS L CE 1 ATOM 3412 N NZ . LYS B 2 45 ? 42.748 38.068 110.824 1.00 12.53 ? 45 LYS L NZ 1 ATOM 3413 N N . LEU B 2 46 ? 47.290 32.863 108.773 1.00 12.70 ? 46 LEU L N 1 ATOM 3414 C CA . LEU B 2 46 ? 47.154 31.583 109.456 1.00 13.05 ? 46 LEU L CA 1 ATOM 3415 C C . LEU B 2 46 ? 45.860 31.701 110.269 1.00 13.41 ? 46 LEU L C 1 ATOM 3416 O O . LEU B 2 46 ? 45.685 32.599 111.100 1.00 13.62 ? 46 LEU L O 1 ATOM 3417 C CB . LEU B 2 46 ? 48.392 31.441 110.325 1.00 14.14 ? 46 LEU L CB 1 ATOM 3418 C CG . LEU B 2 46 ? 48.766 30.249 111.129 1.00 15.48 ? 46 LEU L CG 1 ATOM 3419 C CD1 . LEU B 2 46 ? 49.999 30.672 111.816 1.00 14.39 ? 46 LEU L CD1 1 ATOM 3420 C CD2 . LEU B 2 46 ? 47.748 29.822 112.178 1.00 16.86 ? 46 LEU L CD2 1 ATOM 3421 N N . LEU B 2 47 ? 44.923 30.809 110.055 1.00 13.52 ? 47 LEU L N 1 ATOM 3422 C CA . LEU B 2 47 ? 43.663 30.869 110.763 1.00 11.34 ? 47 LEU L CA 1 ATOM 3423 C C . LEU B 2 47 ? 43.695 29.886 111.920 1.00 9.97 ? 47 LEU L C 1 ATOM 3424 O O . LEU B 2 47 ? 43.441 30.210 113.080 1.00 10.13 ? 47 LEU L O 1 ATOM 3425 C CB . LEU B 2 47 ? 42.546 30.512 109.813 1.00 10.68 ? 47 LEU L CB 1 ATOM 3426 C CG . LEU B 2 47 ? 41.872 31.533 108.943 1.00 9.38 ? 47 LEU L CG 1 ATOM 3427 C CD1 . LEU B 2 47 ? 42.887 32.472 108.398 1.00 9.94 ? 47 LEU L CD1 1 ATOM 3428 C CD2 . LEU B 2 47 ? 41.162 30.841 107.779 1.00 7.67 ? 47 LEU L CD2 1 ATOM 3429 N N . ILE B 2 48 ? 44.022 28.639 111.600 1.00 8.15 ? 48 ILE L N 1 ATOM 3430 C CA . ILE B 2 48 ? 43.977 27.517 112.511 1.00 7.09 ? 48 ILE L CA 1 ATOM 3431 C C . ILE B 2 48 ? 45.277 26.727 112.345 1.00 7.81 ? 48 ILE L C 1 ATOM 3432 O O . ILE B 2 48 ? 45.931 26.765 111.305 1.00 9.16 ? 48 ILE L O 1 ATOM 3433 C CB . ILE B 2 48 ? 42.660 26.774 112.116 1.00 7.11 ? 48 ILE L CB 1 ATOM 3434 C CG1 . ILE B 2 48 ? 41.480 27.519 112.726 1.00 6.45 ? 48 ILE L CG1 1 ATOM 3435 C CG2 . ILE B 2 48 ? 42.673 25.357 112.551 1.00 5.99 ? 48 ILE L CG2 1 ATOM 3436 C CD1 . ILE B 2 48 ? 40.077 27.283 112.151 1.00 8.75 ? 48 ILE L CD1 1 ATOM 3437 N N . TYR B 2 49 ? 45.723 26.093 113.412 1.00 8.53 ? 49 TYR L N 1 ATOM 3438 C CA . TYR B 2 49 ? 46.839 25.181 113.438 1.00 7.13 ? 49 TYR L CA 1 ATOM 3439 C C . TYR B 2 49 ? 46.321 23.988 114.237 1.00 7.19 ? 49 TYR L C 1 ATOM 3440 O O . TYR B 2 49 ? 45.275 24.080 114.878 1.00 4.86 ? 49 TYR L O 1 ATOM 3441 C CB . TYR B 2 49 ? 48.069 25.802 114.133 1.00 5.47 ? 49 TYR L CB 1 ATOM 3442 C CG . TYR B 2 49 ? 47.964 26.480 115.509 1.00 6.64 ? 49 TYR L CG 1 ATOM 3443 C CD1 . TYR B 2 49 ? 47.582 27.803 115.604 1.00 6.56 ? 49 TYR L CD1 1 ATOM 3444 C CD2 . TYR B 2 49 ? 48.310 25.830 116.678 1.00 5.80 ? 49 TYR L CD2 1 ATOM 3445 C CE1 . TYR B 2 49 ? 47.583 28.481 116.818 1.00 5.14 ? 49 TYR L CE1 1 ATOM 3446 C CE2 . TYR B 2 49 ? 48.317 26.508 117.896 1.00 5.51 ? 49 TYR L CE2 1 ATOM 3447 C CZ . TYR B 2 49 ? 47.944 27.838 117.987 1.00 5.16 ? 49 TYR L CZ 1 ATOM 3448 O OH . TYR B 2 49 ? 48.009 28.546 119.185 1.00 6.03 ? 49 TYR L OH 1 ATOM 3449 N N . TRP B 2 50 ? 47.022 22.854 114.262 1.00 7.38 ? 50 TRP L N 1 ATOM 3450 C CA . TRP B 2 50 ? 46.661 21.617 114.928 1.00 6.85 ? 50 TRP L CA 1 ATOM 3451 C C . TRP B 2 50 ? 45.229 21.201 114.723 1.00 6.24 ? 50 TRP L C 1 ATOM 3452 O O . TRP B 2 50 ? 44.511 20.831 115.652 1.00 8.99 ? 50 TRP L O 1 ATOM 3453 C CB . TRP B 2 50 ? 46.956 21.752 116.385 1.00 6.14 ? 50 TRP L CB 1 ATOM 3454 C CG . TRP B 2 50 ? 48.357 21.255 116.692 1.00 6.18 ? 50 TRP L CG 1 ATOM 3455 C CD1 . TRP B 2 50 ? 49.302 22.107 117.195 1.00 5.79 ? 50 TRP L CD1 1 ATOM 3456 C CD2 . TRP B 2 50 ? 48.825 19.971 116.556 1.00 4.65 ? 50 TRP L CD2 1 ATOM 3457 N NE1 . TRP B 2 50 ? 50.357 21.367 117.387 1.00 3.76 ? 50 TRP L NE1 1 ATOM 3458 C CE2 . TRP B 2 50 ? 50.117 20.098 117.028 1.00 5.31 ? 50 TRP L CE2 1 ATOM 3459 C CE3 . TRP B 2 50 ? 48.375 18.741 116.130 1.00 6.07 ? 50 TRP L CE3 1 ATOM 3460 C CZ2 . TRP B 2 50 ? 50.967 19.004 117.072 1.00 6.36 ? 50 TRP L CZ2 1 ATOM 3461 C CZ3 . TRP B 2 50 ? 49.226 17.647 116.175 1.00 6.74 ? 50 TRP L CZ3 1 ATOM 3462 C CH2 . TRP B 2 50 ? 50.515 17.772 116.638 1.00 6.17 ? 50 TRP L CH2 1 ATOM 3463 N N . ALA B 2 51 ? 44.805 21.398 113.469 1.00 5.30 ? 51 ALA L N 1 ATOM 3464 C CA . ALA B 2 51 ? 43.484 21.115 112.918 1.00 6.06 ? 51 ALA L CA 1 ATOM 3465 C C . ALA B 2 51 ? 42.371 22.061 113.397 1.00 8.16 ? 51 ALA L C 1 ATOM 3466 O O . ALA B 2 51 ? 41.627 22.625 112.570 1.00 7.92 ? 51 ALA L O 1 ATOM 3467 C CB . ALA B 2 51 ? 43.031 19.711 113.250 1.00 4.80 ? 51 ALA L CB 1 ATOM 3468 N N . SER B 2 52 ? 42.338 22.346 114.700 1.00 9.80 ? 52 SER L N 1 ATOM 3469 C CA . SER B 2 52 ? 41.338 23.170 115.320 1.00 11.74 ? 52 SER L CA 1 ATOM 3470 C C . SER B 2 52 ? 41.736 24.297 116.210 1.00 13.73 ? 52 SER L C 1 ATOM 3471 O O . SER B 2 52 ? 40.828 24.888 116.778 1.00 17.45 ? 52 SER L O 1 ATOM 3472 C CB . SER B 2 52 ? 40.463 22.298 116.126 1.00 12.44 ? 52 SER L CB 1 ATOM 3473 O OG . SER B 2 52 ? 40.024 21.382 115.140 1.00 15.54 ? 52 SER L OG 1 ATOM 3474 N N . THR B 2 53 ? 42.986 24.674 116.429 1.00 12.07 ? 53 THR L N 1 ATOM 3475 C CA . THR B 2 53 ? 43.224 25.780 117.330 1.00 10.81 ? 53 THR L CA 1 ATOM 3476 C C . THR B 2 53 ? 43.387 27.072 116.542 1.00 10.54 ? 53 THR L C 1 ATOM 3477 O O . THR B 2 53 ? 44.220 27.163 115.642 1.00 11.74 ? 53 THR L O 1 ATOM 3478 C CB . THR B 2 53 ? 44.476 25.453 118.194 1.00 10.56 ? 53 THR L CB 1 ATOM 3479 O OG1 . THR B 2 53 ? 44.127 24.469 119.229 1.00 9.51 ? 53 THR L OG1 1 ATOM 3480 C CG2 . THR B 2 53 ? 44.961 26.715 118.905 1.00 10.32 ? 53 THR L CG2 1 ATOM 3481 N N . ARG B 2 54 ? 42.555 28.081 116.825 1.00 8.54 ? 54 ARG L N 1 ATOM 3482 C CA . ARG B 2 54 ? 42.684 29.378 116.177 1.00 7.21 ? 54 ARG L CA 1 ATOM 3483 C C . ARG B 2 54 ? 43.872 30.212 116.596 1.00 6.96 ? 54 ARG L C 1 ATOM 3484 O O . ARG B 2 54 ? 44.301 30.291 117.747 1.00 7.52 ? 54 ARG L O 1 ATOM 3485 C CB . ARG B 2 54 ? 41.404 30.160 116.413 1.00 9.17 ? 54 ARG L CB 1 ATOM 3486 C CG . ARG B 2 54 ? 40.229 29.467 115.684 1.00 11.66 ? 54 ARG L CG 1 ATOM 3487 C CD . ARG B 2 54 ? 38.868 30.195 115.705 1.00 13.34 ? 54 ARG L CD 1 ATOM 3488 N NE . ARG B 2 54 ? 38.390 30.317 117.080 1.00 13.18 ? 54 ARG L NE 1 ATOM 3489 C CZ . ARG B 2 54 ? 37.573 29.412 117.642 1.00 14.48 ? 54 ARG L CZ 1 ATOM 3490 N NH1 . ARG B 2 54 ? 37.045 28.328 116.995 1.00 13.61 ? 54 ARG L NH1 1 ATOM 3491 N NH2 . ARG B 2 54 ? 37.286 29.680 118.913 1.00 16.20 ? 54 ARG L NH2 1 ATOM 3492 N N . HIS B 2 55 ? 44.423 30.853 115.594 1.00 6.83 ? 55 HIS L N 1 ATOM 3493 C CA . HIS B 2 55 ? 45.573 31.711 115.829 1.00 9.82 ? 55 HIS L CA 1 ATOM 3494 C C . HIS B 2 55 ? 45.000 33.020 116.369 1.00 13.26 ? 55 HIS L C 1 ATOM 3495 O O . HIS B 2 55 ? 43.776 33.245 116.381 1.00 13.93 ? 55 HIS L O 1 ATOM 3496 C CB . HIS B 2 55 ? 46.350 31.933 114.542 1.00 8.33 ? 55 HIS L CB 1 ATOM 3497 C CG . HIS B 2 55 ? 47.660 32.659 114.752 1.00 10.29 ? 55 HIS L CG 1 ATOM 3498 N ND1 . HIS B 2 55 ? 47.953 33.884 114.353 1.00 10.56 ? 55 HIS L ND1 1 ATOM 3499 C CD2 . HIS B 2 55 ? 48.755 32.171 115.438 1.00 10.11 ? 55 HIS L CD2 1 ATOM 3500 C CE1 . HIS B 2 55 ? 49.171 34.163 114.760 1.00 12.61 ? 55 HIS L CE1 1 ATOM 3501 N NE2 . HIS B 2 55 ? 49.658 33.134 115.411 1.00 12.08 ? 55 HIS L NE2 1 ATOM 3502 N N . ILE B 2 56 ? 45.898 33.921 116.781 1.00 16.35 ? 56 ILE L N 1 ATOM 3503 C CA . ILE B 2 56 ? 45.489 35.032 117.603 1.00 18.09 ? 56 ILE L CA 1 ATOM 3504 C C . ILE B 2 56 ? 44.727 36.028 116.768 1.00 19.26 ? 56 ILE L C 1 ATOM 3505 O O . ILE B 2 56 ? 45.201 36.656 115.836 1.00 17.81 ? 56 ILE L O 1 ATOM 3506 C CB . ILE B 2 56 ? 46.795 35.623 118.389 1.00 18.20 ? 56 ILE L CB 1 ATOM 3507 C CG1 . ILE B 2 56 ? 46.417 36.924 119.076 1.00 17.86 ? 56 ILE L CG1 1 ATOM 3508 C CG2 . ILE B 2 56 ? 47.976 35.856 117.510 1.00 20.33 ? 56 ILE L CG2 1 ATOM 3509 C CD1 . ILE B 2 56 ? 47.277 37.176 120.329 1.00 17.40 ? 56 ILE L CD1 1 ATOM 3510 N N . GLY B 2 57 ? 43.438 35.862 116.991 1.00 23.35 ? 57 GLY L N 1 ATOM 3511 C CA . GLY B 2 57 ? 42.460 36.801 116.501 1.00 24.80 ? 57 GLY L CA 1 ATOM 3512 C C . GLY B 2 57 ? 41.687 36.324 115.285 1.00 25.53 ? 57 GLY L C 1 ATOM 3513 O O . GLY B 2 57 ? 41.158 37.181 114.575 1.00 25.90 ? 57 GLY L O 1 ATOM 3514 N N . VAL B 2 58 ? 41.593 35.032 114.956 1.00 25.22 ? 58 VAL L N 1 ATOM 3515 C CA . VAL B 2 58 ? 40.710 34.705 113.856 1.00 23.56 ? 58 VAL L CA 1 ATOM 3516 C C . VAL B 2 58 ? 39.403 34.441 114.583 1.00 25.66 ? 58 VAL L C 1 ATOM 3517 O O . VAL B 2 58 ? 39.359 33.606 115.493 1.00 27.90 ? 58 VAL L O 1 ATOM 3518 C CB . VAL B 2 58 ? 41.222 33.463 112.966 1.00 20.50 ? 58 VAL L CB 1 ATOM 3519 C CG1 . VAL B 2 58 ? 42.720 33.326 113.226 1.00 18.17 ? 58 VAL L CG1 1 ATOM 3520 C CG2 . VAL B 2 58 ? 40.369 32.205 113.129 1.00 18.57 ? 58 VAL L CG2 1 ATOM 3521 N N . PRO B 2 59 ? 38.353 35.247 114.326 1.00 26.98 ? 59 PRO L N 1 ATOM 3522 C CA . PRO B 2 59 ? 37.085 35.140 115.043 1.00 28.03 ? 59 PRO L CA 1 ATOM 3523 C C . PRO B 2 59 ? 36.428 33.774 114.880 1.00 28.37 ? 59 PRO L C 1 ATOM 3524 O O . PRO B 2 59 ? 36.342 33.252 113.761 1.00 29.49 ? 59 PRO L O 1 ATOM 3525 C CB . PRO B 2 59 ? 36.263 36.311 114.509 1.00 28.25 ? 59 PRO L CB 1 ATOM 3526 C CG . PRO B 2 59 ? 36.928 36.796 113.234 1.00 27.34 ? 59 PRO L CG 1 ATOM 3527 C CD . PRO B 2 59 ? 38.376 36.413 113.427 1.00 26.44 ? 59 PRO L CD 1 ATOM 3528 N N . ASP B 2 60 ? 35.968 33.198 115.996 1.00 31.42 ? 60 ASP L N 1 ATOM 3529 C CA . ASP B 2 60 ? 35.309 31.889 116.089 1.00 33.49 ? 60 ASP L CA 1 ATOM 3530 C C . ASP B 2 60 ? 34.348 31.383 115.008 1.00 31.39 ? 60 ASP L C 1 ATOM 3531 O O . ASP B 2 60 ? 33.767 30.310 115.120 1.00 32.46 ? 60 ASP L O 1 ATOM 3532 C CB . ASP B 2 60 ? 34.576 31.807 117.449 1.00 37.62 ? 60 ASP L CB 1 ATOM 3533 C CG . ASP B 2 60 ? 33.896 33.100 117.916 1.00 41.67 ? 60 ASP L CG 1 ATOM 3534 O OD1 . ASP B 2 60 ? 33.067 33.675 117.200 1.00 44.98 ? 60 ASP L OD1 1 ATOM 3535 O OD2 . ASP B 2 60 ? 34.222 33.543 119.013 1.00 44.71 ? 60 ASP L OD2 1 ATOM 3536 N N . ARG B 2 61 ? 34.067 32.129 113.953 1.00 28.48 ? 61 ARG L N 1 ATOM 3537 C CA . ARG B 2 61 ? 33.297 31.642 112.826 1.00 24.49 ? 61 ARG L CA 1 ATOM 3538 C C . ARG B 2 61 ? 33.930 30.460 112.148 1.00 23.98 ? 61 ARG L C 1 ATOM 3539 O O . ARG B 2 61 ? 33.216 29.670 111.525 1.00 26.46 ? 61 ARG L O 1 ATOM 3540 C CB . ARG B 2 61 ? 33.149 32.665 111.750 1.00 22.82 ? 61 ARG L CB 1 ATOM 3541 C CG . ARG B 2 61 ? 32.116 33.694 112.021 1.00 22.29 ? 61 ARG L CG 1 ATOM 3542 C CD . ARG B 2 61 ? 32.720 35.091 112.128 1.00 21.66 ? 61 ARG L CD 1 ATOM 3543 N NE . ARG B 2 61 ? 33.497 35.543 110.988 1.00 22.59 ? 61 ARG L NE 1 ATOM 3544 C CZ . ARG B 2 61 ? 33.071 35.537 109.726 1.00 24.23 ? 61 ARG L CZ 1 ATOM 3545 N NH1 . ARG B 2 61 ? 31.868 35.100 109.346 1.00 27.00 ? 61 ARG L NH1 1 ATOM 3546 N NH2 . ARG B 2 61 ? 33.891 36.044 108.818 1.00 25.24 ? 61 ARG L NH2 1 ATOM 3547 N N . PHE B 2 62 ? 35.267 30.479 112.208 1.00 22.00 ? 62 PHE L N 1 ATOM 3548 C CA . PHE B 2 62 ? 36.157 29.512 111.582 1.00 17.02 ? 62 PHE L CA 1 ATOM 3549 C C . PHE B 2 62 ? 36.395 28.424 112.584 1.00 15.01 ? 62 PHE L C 1 ATOM 3550 O O . PHE B 2 62 ? 36.922 28.616 113.684 1.00 13.41 ? 62 PHE L O 1 ATOM 3551 C CB . PHE B 2 62 ? 37.511 30.086 111.234 1.00 17.58 ? 62 PHE L CB 1 ATOM 3552 C CG . PHE B 2 62 ? 37.411 31.253 110.278 1.00 17.16 ? 62 PHE L CG 1 ATOM 3553 C CD1 . PHE B 2 62 ? 36.778 32.415 110.646 1.00 18.63 ? 62 PHE L CD1 1 ATOM 3554 C CD2 . PHE B 2 62 ? 37.956 31.159 109.028 1.00 18.01 ? 62 PHE L CD2 1 ATOM 3555 C CE1 . PHE B 2 62 ? 36.687 33.465 109.781 1.00 20.81 ? 62 PHE L CE1 1 ATOM 3556 C CE2 . PHE B 2 62 ? 37.861 32.213 108.165 1.00 20.90 ? 62 PHE L CE2 1 ATOM 3557 C CZ . PHE B 2 62 ? 37.232 33.363 108.541 1.00 22.51 ? 62 PHE L CZ 1 ATOM 3558 N N . ALA B 2 63 ? 36.025 27.247 112.140 1.00 14.46 ? 63 ALA L N 1 ATOM 3559 C CA . ALA B 2 63 ? 36.065 26.062 112.957 1.00 15.44 ? 63 ALA L CA 1 ATOM 3560 C C . ALA B 2 63 ? 36.833 24.995 112.198 1.00 16.58 ? 63 ALA L C 1 ATOM 3561 O O . ALA B 2 63 ? 36.415 24.446 111.164 1.00 16.28 ? 63 ALA L O 1 ATOM 3562 C CB . ALA B 2 63 ? 34.632 25.615 113.228 1.00 16.39 ? 63 ALA L CB 1 ATOM 3563 N N . GLY B 2 64 ? 38.042 24.803 112.699 1.00 17.79 ? 64 GLY L N 1 ATOM 3564 C CA . GLY B 2 64 ? 38.853 23.725 112.170 1.00 17.33 ? 64 GLY L CA 1 ATOM 3565 C C . GLY B 2 64 ? 38.381 22.392 112.714 1.00 18.33 ? 64 GLY L C 1 ATOM 3566 O O . GLY B 2 64 ? 37.777 22.365 113.791 1.00 18.47 ? 64 GLY L O 1 ATOM 3567 N N . SER B 2 65 ? 38.654 21.301 112.002 1.00 19.06 ? 65 SER L N 1 ATOM 3568 C CA . SER B 2 65 ? 38.345 19.944 112.426 1.00 20.04 ? 65 SER L CA 1 ATOM 3569 C C . SER B 2 65 ? 39.085 18.805 111.723 1.00 19.19 ? 65 SER L C 1 ATOM 3570 O O . SER B 2 65 ? 39.896 18.977 110.788 1.00 20.47 ? 65 SER L O 1 ATOM 3571 C CB . SER B 2 65 ? 36.869 19.687 112.263 1.00 22.18 ? 65 SER L CB 1 ATOM 3572 O OG . SER B 2 65 ? 36.418 19.692 113.597 1.00 27.53 ? 65 SER L OG 1 ATOM 3573 N N . GLY B 2 66 ? 38.837 17.602 112.226 1.00 19.59 ? 66 GLY L N 1 ATOM 3574 C CA . GLY B 2 66 ? 39.330 16.434 111.541 1.00 21.68 ? 66 GLY L CA 1 ATOM 3575 C C . GLY B 2 66 ? 40.200 15.545 112.396 1.00 23.64 ? 66 GLY L C 1 ATOM 3576 O O . GLY B 2 66 ? 40.409 15.797 113.582 1.00 25.44 ? 66 GLY L O 1 ATOM 3577 N N . SER B 2 67 ? 40.727 14.544 111.696 1.00 25.44 ? 67 SER L N 1 ATOM 3578 C CA . SER B 2 67 ? 41.471 13.444 112.259 1.00 25.84 ? 67 SER L CA 1 ATOM 3579 C C . SER B 2 67 ? 42.158 12.662 111.139 1.00 25.89 ? 67 SER L C 1 ATOM 3580 O O . SER B 2 67 ? 41.794 12.834 109.972 1.00 26.83 ? 67 SER L O 1 ATOM 3581 C CB . SER B 2 67 ? 40.449 12.601 112.981 1.00 26.84 ? 67 SER L CB 1 ATOM 3582 O OG . SER B 2 67 ? 40.874 11.348 113.499 1.00 28.38 ? 67 SER L OG 1 ATOM 3583 N N . GLY B 2 68 ? 43.137 11.801 111.447 1.00 24.97 ? 68 GLY L N 1 ATOM 3584 C CA . GLY B 2 68 ? 43.692 10.855 110.482 1.00 21.74 ? 68 GLY L CA 1 ATOM 3585 C C . GLY B 2 68 ? 44.158 11.473 109.189 1.00 21.75 ? 68 GLY L C 1 ATOM 3586 O O . GLY B 2 68 ? 45.109 12.241 109.236 1.00 20.95 ? 68 GLY L O 1 ATOM 3587 N N . THR B 2 69 ? 43.562 11.090 108.060 1.00 22.11 ? 69 THR L N 1 ATOM 3588 C CA . THR B 2 69 ? 43.837 11.662 106.740 1.00 20.74 ? 69 THR L CA 1 ATOM 3589 C C . THR B 2 69 ? 42.727 12.617 106.305 1.00 19.86 ? 69 THR L C 1 ATOM 3590 O O . THR B 2 69 ? 42.835 13.168 105.204 1.00 19.61 ? 69 THR L O 1 ATOM 3591 C CB . THR B 2 69 ? 43.934 10.612 105.580 1.00 21.17 ? 69 THR L CB 1 ATOM 3592 O OG1 . THR B 2 69 ? 43.010 9.549 105.792 1.00 21.81 ? 69 THR L OG1 1 ATOM 3593 C CG2 . THR B 2 69 ? 45.280 10.019 105.506 1.00 21.61 ? 69 THR L CG2 1 ATOM 3594 N N . ASP B 2 70 ? 41.664 12.816 107.097 1.00 20.80 ? 70 ASP L N 1 ATOM 3595 C CA . ASP B 2 70 ? 40.534 13.614 106.669 1.00 21.46 ? 70 ASP L CA 1 ATOM 3596 C C . ASP B 2 70 ? 40.205 14.718 107.662 1.00 19.68 ? 70 ASP L C 1 ATOM 3597 O O . ASP B 2 70 ? 39.842 14.504 108.819 1.00 21.09 ? 70 ASP L O 1 ATOM 3598 C CB . ASP B 2 70 ? 39.337 12.653 106.429 1.00 22.76 ? 70 ASP L CB 1 ATOM 3599 C CG . ASP B 2 70 ? 39.295 12.062 105.003 1.00 24.28 ? 70 ASP L CG 1 ATOM 3600 O OD1 . ASP B 2 70 ? 40.130 11.213 104.667 1.00 24.12 ? 70 ASP L OD1 1 ATOM 3601 O OD2 . ASP B 2 70 ? 38.433 12.450 104.210 1.00 26.63 ? 70 ASP L OD2 1 ATOM 3602 N N . TYR B 2 71 ? 40.329 15.942 107.157 1.00 17.27 ? 71 TYR L N 1 ATOM 3603 C CA . TYR B 2 71 ? 40.175 17.175 107.899 1.00 14.11 ? 71 TYR L CA 1 ATOM 3604 C C . TYR B 2 71 ? 39.208 18.060 107.137 1.00 13.32 ? 71 TYR L C 1 ATOM 3605 O O . TYR B 2 71 ? 39.005 17.861 105.926 1.00 12.63 ? 71 TYR L O 1 ATOM 3606 C CB . TYR B 2 71 ? 41.544 17.851 108.009 1.00 10.96 ? 71 TYR L CB 1 ATOM 3607 C CG . TYR B 2 71 ? 42.552 16.996 108.809 1.00 9.53 ? 71 TYR L CG 1 ATOM 3608 C CD1 . TYR B 2 71 ? 42.555 17.068 110.204 1.00 9.58 ? 71 TYR L CD1 1 ATOM 3609 C CD2 . TYR B 2 71 ? 43.418 16.099 108.160 1.00 7.57 ? 71 TYR L CD2 1 ATOM 3610 C CE1 . TYR B 2 71 ? 43.394 16.253 110.931 1.00 8.64 ? 71 TYR L CE1 1 ATOM 3611 C CE2 . TYR B 2 71 ? 44.261 15.286 108.905 1.00 7.07 ? 71 TYR L CE2 1 ATOM 3612 C CZ . TYR B 2 71 ? 44.226 15.373 110.283 1.00 7.39 ? 71 TYR L CZ 1 ATOM 3613 O OH . TYR B 2 71 ? 44.972 14.503 111.049 1.00 10.29 ? 71 TYR L OH 1 ATOM 3614 N N . THR B 2 72 ? 38.623 19.070 107.792 1.00 13.40 ? 72 THR L N 1 ATOM 3615 C CA . THR B 2 72 ? 37.699 20.012 107.154 1.00 13.83 ? 72 THR L CA 1 ATOM 3616 C C . THR B 2 72 ? 37.687 21.382 107.860 1.00 11.42 ? 72 THR L C 1 ATOM 3617 O O . THR B 2 72 ? 37.944 21.405 109.071 1.00 11.47 ? 72 THR L O 1 ATOM 3618 C CB . THR B 2 72 ? 36.302 19.279 107.109 1.00 14.33 ? 72 THR L CB 1 ATOM 3619 O OG1 . THR B 2 72 ? 35.505 20.119 106.264 1.00 17.28 ? 72 THR L OG1 1 ATOM 3620 C CG2 . THR B 2 72 ? 35.667 18.969 108.470 1.00 16.66 ? 72 THR L CG2 1 ATOM 3621 N N . LEU B 2 73 ? 37.539 22.525 107.178 1.00 10.45 ? 73 LEU L N 1 ATOM 3622 C CA . LEU B 2 73 ? 37.442 23.834 107.827 1.00 8.64 ? 73 LEU L CA 1 ATOM 3623 C C . LEU B 2 73 ? 36.065 24.416 107.614 1.00 8.48 ? 73 LEU L C 1 ATOM 3624 O O . LEU B 2 73 ? 35.731 24.760 106.486 1.00 7.19 ? 73 LEU L O 1 ATOM 3625 C CB . LEU B 2 73 ? 38.407 24.892 107.272 1.00 6.11 ? 73 LEU L CB 1 ATOM 3626 C CG . LEU B 2 73 ? 38.275 26.380 107.723 1.00 3.12 ? 73 LEU L CG 1 ATOM 3627 C CD1 . LEU B 2 73 ? 39.111 26.650 108.935 1.00 2.03 ? 73 LEU L CD1 1 ATOM 3628 C CD2 . LEU B 2 73 ? 38.826 27.297 106.669 1.00 2.03 ? 73 LEU L CD2 1 ATOM 3629 N N . THR B 2 74 ? 35.248 24.546 108.632 1.00 11.59 ? 74 THR L N 1 ATOM 3630 C CA . THR B 2 74 ? 33.925 25.135 108.514 1.00 15.55 ? 74 THR L CA 1 ATOM 3631 C C . THR B 2 74 ? 33.928 26.687 108.737 1.00 16.62 ? 74 THR L C 1 ATOM 3632 O O . THR B 2 74 ? 34.702 27.210 109.561 1.00 18.96 ? 74 THR L O 1 ATOM 3633 C CB . THR B 2 74 ? 33.044 24.333 109.546 1.00 16.24 ? 74 THR L CB 1 ATOM 3634 O OG1 . THR B 2 74 ? 33.428 22.945 109.477 1.00 19.03 ? 74 THR L OG1 1 ATOM 3635 C CG2 . THR B 2 74 ? 31.542 24.440 109.254 1.00 15.77 ? 74 THR L CG2 1 ATOM 3636 N N . ILE B 2 75 ? 33.132 27.504 108.014 1.00 18.08 ? 75 ILE L N 1 ATOM 3637 C CA . ILE B 2 75 ? 33.021 28.944 108.258 1.00 18.54 ? 75 ILE L CA 1 ATOM 3638 C C . ILE B 2 75 ? 31.520 29.113 108.346 1.00 21.50 ? 75 ILE L C 1 ATOM 3639 O O . ILE B 2 75 ? 30.811 28.481 107.549 1.00 22.62 ? 75 ILE L O 1 ATOM 3640 C CB . ILE B 2 75 ? 33.480 29.849 107.090 1.00 17.48 ? 75 ILE L CB 1 ATOM 3641 C CG1 . ILE B 2 75 ? 34.859 29.472 106.614 1.00 15.64 ? 75 ILE L CG1 1 ATOM 3642 C CG2 . ILE B 2 75 ? 33.457 31.299 107.571 1.00 14.96 ? 75 ILE L CG2 1 ATOM 3643 C CD1 . ILE B 2 75 ? 35.261 30.175 105.339 1.00 14.31 ? 75 ILE L CD1 1 ATOM 3644 N N . SER B 2 76 ? 31.035 29.902 109.327 1.00 25.51 ? 76 SER L N 1 ATOM 3645 C CA . SER B 2 76 ? 29.606 30.250 109.448 1.00 27.85 ? 76 SER L CA 1 ATOM 3646 C C . SER B 2 76 ? 29.368 31.755 109.316 1.00 28.50 ? 76 SER L C 1 ATOM 3647 O O . SER B 2 76 ? 30.296 32.563 109.386 1.00 29.16 ? 76 SER L O 1 ATOM 3648 C CB . SER B 2 76 ? 29.034 29.826 110.794 1.00 30.62 ? 76 SER L CB 1 ATOM 3649 O OG . SER B 2 76 ? 29.491 28.518 111.108 1.00 31.30 ? 76 SER L OG 1 ATOM 3650 N N . SER B 2 77 ? 28.108 32.139 109.128 1.00 27.59 ? 77 SER L N 1 ATOM 3651 C CA . SER B 2 77 ? 27.714 33.520 108.923 1.00 26.41 ? 77 SER L CA 1 ATOM 3652 C C . SER B 2 77 ? 28.602 34.285 107.938 1.00 24.65 ? 77 SER L C 1 ATOM 3653 O O . SER B 2 77 ? 28.925 35.479 108.069 1.00 25.11 ? 77 SER L O 1 ATOM 3654 C CB . SER B 2 77 ? 27.667 34.240 110.267 1.00 27.34 ? 77 SER L CB 1 ATOM 3655 O OG . SER B 2 77 ? 26.311 34.394 110.701 1.00 30.50 ? 77 SER L OG 1 ATOM 3656 N N . VAL B 2 78 ? 28.812 33.538 106.843 1.00 21.29 ? 78 VAL L N 1 ATOM 3657 C CA . VAL B 2 78 ? 29.682 33.956 105.778 1.00 20.41 ? 78 VAL L CA 1 ATOM 3658 C C . VAL B 2 78 ? 29.370 35.370 105.276 1.00 21.74 ? 78 VAL L C 1 ATOM 3659 O O . VAL B 2 78 ? 28.260 35.815 104.983 1.00 22.63 ? 78 VAL L O 1 ATOM 3660 C CB . VAL B 2 78 ? 29.578 32.868 104.694 1.00 18.09 ? 78 VAL L CB 1 ATOM 3661 C CG1 . VAL B 2 78 ? 30.441 33.226 103.503 1.00 17.41 ? 78 VAL L CG1 1 ATOM 3662 C CG2 . VAL B 2 78 ? 30.127 31.567 105.230 1.00 17.98 ? 78 VAL L CG2 1 ATOM 3663 N N . GLN B 2 79 ? 30.487 36.070 105.330 1.00 22.09 ? 79 GLN L N 1 ATOM 3664 C CA . GLN B 2 79 ? 30.612 37.490 105.126 1.00 25.41 ? 79 GLN L CA 1 ATOM 3665 C C . GLN B 2 79 ? 30.988 37.732 103.671 1.00 25.57 ? 79 GLN L C 1 ATOM 3666 O O . GLN B 2 79 ? 31.736 36.935 103.082 1.00 24.81 ? 79 GLN L O 1 ATOM 3667 C CB . GLN B 2 79 ? 31.693 37.910 106.107 1.00 26.61 ? 79 GLN L CB 1 ATOM 3668 C CG . GLN B 2 79 ? 31.630 39.322 106.620 1.00 30.09 ? 79 GLN L CG 1 ATOM 3669 C CD . GLN B 2 79 ? 31.920 39.380 108.115 1.00 31.92 ? 79 GLN L CD 1 ATOM 3670 O OE1 . GLN B 2 79 ? 33.056 39.547 108.542 1.00 32.78 ? 79 GLN L OE1 1 ATOM 3671 N NE2 . GLN B 2 79 ? 30.942 39.278 109.007 1.00 32.21 ? 79 GLN L NE2 1 ATOM 3672 N N . ALA B 2 80 ? 30.566 38.820 103.035 1.00 24.81 ? 80 ALA L N 1 ATOM 3673 C CA . ALA B 2 80 ? 31.004 39.087 101.667 1.00 23.71 ? 80 ALA L CA 1 ATOM 3674 C C . ALA B 2 80 ? 32.503 39.294 101.627 1.00 24.24 ? 80 ALA L C 1 ATOM 3675 O O . ALA B 2 80 ? 33.076 39.278 100.549 1.00 24.71 ? 80 ALA L O 1 ATOM 3676 C CB . ALA B 2 80 ? 30.369 40.341 101.093 1.00 23.14 ? 80 ALA L CB 1 ATOM 3677 N N . GLU B 2 81 ? 33.190 39.484 102.755 1.00 25.65 ? 81 GLU L N 1 ATOM 3678 C CA . GLU B 2 81 ? 34.626 39.613 102.697 1.00 28.19 ? 81 GLU L CA 1 ATOM 3679 C C . GLU B 2 81 ? 35.248 38.261 103.050 1.00 27.26 ? 81 GLU L C 1 ATOM 3680 O O . GLU B 2 81 ? 36.398 38.190 103.472 1.00 28.65 ? 81 GLU L O 1 ATOM 3681 C CB . GLU B 2 81 ? 35.050 40.760 103.671 1.00 32.41 ? 81 GLU L CB 1 ATOM 3682 C CG . GLU B 2 81 ? 36.366 41.537 103.322 1.00 37.89 ? 81 GLU L CG 1 ATOM 3683 C CD . GLU B 2 81 ? 36.289 43.008 102.799 1.00 41.76 ? 81 GLU L CD 1 ATOM 3684 O OE1 . GLU B 2 81 ? 35.689 43.868 103.475 1.00 42.50 ? 81 GLU L OE1 1 ATOM 3685 O OE2 . GLU B 2 81 ? 36.868 43.310 101.735 1.00 44.53 ? 81 GLU L OE2 1 ATOM 3686 N N . ASP B 2 82 ? 34.544 37.135 102.911 1.00 24.54 ? 82 ASP L N 1 ATOM 3687 C CA . ASP B 2 82 ? 35.186 35.869 103.226 1.00 20.32 ? 82 ASP L CA 1 ATOM 3688 C C . ASP B 2 82 ? 35.841 35.167 102.067 1.00 20.56 ? 82 ASP L C 1 ATOM 3689 O O . ASP B 2 82 ? 36.516 34.136 102.206 1.00 21.96 ? 82 ASP L O 1 ATOM 3690 C CB . ASP B 2 82 ? 34.204 34.928 103.849 1.00 17.78 ? 82 ASP L CB 1 ATOM 3691 C CG . ASP B 2 82 ? 34.087 35.142 105.345 1.00 16.62 ? 82 ASP L CG 1 ATOM 3692 O OD1 . ASP B 2 82 ? 34.968 35.766 105.954 1.00 12.44 ? 82 ASP L OD1 1 ATOM 3693 O OD2 . ASP B 2 82 ? 33.118 34.651 105.919 1.00 19.92 ? 82 ASP L OD2 1 ATOM 3694 N N . LEU B 2 83 ? 35.628 35.856 100.947 1.00 18.10 ? 83 LEU L N 1 ATOM 3695 C CA . LEU B 2 83 ? 36.091 35.496 99.646 1.00 16.21 ? 83 LEU L CA 1 ATOM 3696 C C . LEU B 2 83 ? 37.591 35.495 99.716 1.00 16.77 ? 83 LEU L C 1 ATOM 3697 O O . LEU B 2 83 ? 38.209 36.522 100.011 1.00 20.06 ? 83 LEU L O 1 ATOM 3698 C CB . LEU B 2 83 ? 35.568 36.538 98.670 1.00 18.23 ? 83 LEU L CB 1 ATOM 3699 C CG . LEU B 2 83 ? 36.269 36.782 97.343 1.00 19.74 ? 83 LEU L CG 1 ATOM 3700 C CD1 . LEU B 2 83 ? 35.626 35.950 96.264 1.00 20.39 ? 83 LEU L CD1 1 ATOM 3701 C CD2 . LEU B 2 83 ? 36.239 38.262 97.058 1.00 21.59 ? 83 LEU L CD2 1 ATOM 3702 N N . ALA B 2 84 ? 38.114 34.310 99.441 1.00 15.40 ? 84 ALA L N 1 ATOM 3703 C CA . ALA B 2 84 ? 39.532 34.090 99.456 1.00 13.36 ? 84 ALA L CA 1 ATOM 3704 C C . ALA B 2 84 ? 39.766 32.653 99.047 1.00 12.63 ? 84 ALA L C 1 ATOM 3705 O O . ALA B 2 84 ? 38.819 31.872 98.869 1.00 9.49 ? 84 ALA L O 1 ATOM 3706 C CB . ALA B 2 84 ? 40.077 34.278 100.848 1.00 12.12 ? 84 ALA L CB 1 ATOM 3707 N N . LEU B 2 85 ? 41.069 32.401 98.872 1.00 12.66 ? 85 LEU L N 1 ATOM 3708 C CA . LEU B 2 85 ? 41.627 31.104 98.564 1.00 11.98 ? 85 LEU L CA 1 ATOM 3709 C C . LEU B 2 85 ? 42.098 30.485 99.856 1.00 12.72 ? 85 LEU L C 1 ATOM 3710 O O . LEU B 2 85 ? 42.953 31.069 100.515 1.00 14.01 ? 85 LEU L O 1 ATOM 3711 C CB . LEU B 2 85 ? 42.760 31.314 97.619 1.00 12.52 ? 85 LEU L CB 1 ATOM 3712 C CG . LEU B 2 85 ? 42.409 30.904 96.210 1.00 11.90 ? 85 LEU L CG 1 ATOM 3713 C CD1 . LEU B 2 85 ? 43.521 31.427 95.293 1.00 12.15 ? 85 LEU L CD1 1 ATOM 3714 C CD2 . LEU B 2 85 ? 42.151 29.365 96.157 1.00 9.57 ? 85 LEU L CD2 1 ATOM 3715 N N . TYR B 2 86 ? 41.542 29.340 100.221 1.00 12.21 ? 86 TYR L N 1 ATOM 3716 C CA . TYR B 2 86 ? 41.795 28.649 101.474 1.00 13.26 ? 86 TYR L CA 1 ATOM 3717 C C . TYR B 2 86 ? 42.713 27.467 101.234 1.00 13.69 ? 86 TYR L C 1 ATOM 3718 O O . TYR B 2 86 ? 42.401 26.679 100.332 1.00 16.33 ? 86 TYR L O 1 ATOM 3719 C CB . TYR B 2 86 ? 40.470 28.155 102.072 1.00 12.47 ? 86 TYR L CB 1 ATOM 3720 C CG . TYR B 2 86 ? 39.669 29.307 102.644 1.00 14.08 ? 86 TYR L CG 1 ATOM 3721 C CD1 . TYR B 2 86 ? 38.885 30.125 101.860 1.00 14.40 ? 86 TYR L CD1 1 ATOM 3722 C CD2 . TYR B 2 86 ? 39.803 29.600 103.970 1.00 13.33 ? 86 TYR L CD2 1 ATOM 3723 C CE1 . TYR B 2 86 ? 38.260 31.225 102.409 1.00 13.21 ? 86 TYR L CE1 1 ATOM 3724 C CE2 . TYR B 2 86 ? 39.179 30.694 104.516 1.00 12.80 ? 86 TYR L CE2 1 ATOM 3725 C CZ . TYR B 2 86 ? 38.430 31.500 103.735 1.00 12.14 ? 86 TYR L CZ 1 ATOM 3726 O OH . TYR B 2 86 ? 37.935 32.637 104.308 1.00 12.88 ? 86 TYR L OH 1 ATOM 3727 N N . TYR B 2 87 ? 43.805 27.289 101.998 1.00 12.30 ? 87 TYR L N 1 ATOM 3728 C CA . TYR B 2 87 ? 44.777 26.221 101.742 1.00 10.30 ? 87 TYR L CA 1 ATOM 3729 C C . TYR B 2 87 ? 45.024 25.378 102.971 1.00 8.51 ? 87 TYR L C 1 ATOM 3730 O O . TYR B 2 87 ? 45.090 26.034 104.021 1.00 9.36 ? 87 TYR L O 1 ATOM 3731 C CB . TYR B 2 87 ? 46.157 26.752 101.357 1.00 10.77 ? 87 TYR L CB 1 ATOM 3732 C CG . TYR B 2 87 ? 46.233 27.591 100.115 1.00 10.93 ? 87 TYR L CG 1 ATOM 3733 C CD1 . TYR B 2 87 ? 46.347 26.958 98.895 1.00 12.27 ? 87 TYR L CD1 1 ATOM 3734 C CD2 . TYR B 2 87 ? 46.193 28.972 100.219 1.00 11.84 ? 87 TYR L CD2 1 ATOM 3735 C CE1 . TYR B 2 87 ? 46.409 27.723 97.741 1.00 12.23 ? 87 TYR L CE1 1 ATOM 3736 C CE2 . TYR B 2 87 ? 46.259 29.746 99.075 1.00 12.18 ? 87 TYR L CE2 1 ATOM 3737 C CZ . TYR B 2 87 ? 46.375 29.104 97.854 1.00 12.63 ? 87 TYR L CZ 1 ATOM 3738 O OH . TYR B 2 87 ? 46.466 29.838 96.708 1.00 16.59 ? 87 TYR L OH 1 ATOM 3739 N N . CYS B 2 88 ? 45.151 24.040 102.974 1.00 5.93 ? 88 CYS L N 1 ATOM 3740 C CA . CYS B 2 88 ? 45.684 23.454 104.197 1.00 6.67 ? 88 CYS L CA 1 ATOM 3741 C C . CYS B 2 88 ? 47.167 23.151 104.057 1.00 7.14 ? 88 CYS L C 1 ATOM 3742 O O . CYS B 2 88 ? 47.649 22.733 103.005 1.00 9.08 ? 88 CYS L O 1 ATOM 3743 C CB . CYS B 2 88 ? 44.967 22.183 104.573 1.00 5.73 ? 88 CYS L CB 1 ATOM 3744 S SG . CYS B 2 88 ? 44.785 21.171 103.111 1.00 6.34 ? 88 CYS L SG 1 ATOM 3745 N N . GLN B 2 89 ? 47.985 23.512 105.019 1.00 5.90 ? 89 GLN L N 1 ATOM 3746 C CA . GLN B 2 89 ? 49.388 23.099 105.025 1.00 5.31 ? 89 GLN L CA 1 ATOM 3747 C C . GLN B 2 89 ? 49.352 21.943 105.987 1.00 6.39 ? 89 GLN L C 1 ATOM 3748 O O . GLN B 2 89 ? 48.436 21.882 106.828 1.00 8.32 ? 89 GLN L O 1 ATOM 3749 C CB . GLN B 2 89 ? 50.338 24.128 105.627 1.00 2.06 ? 89 GLN L CB 1 ATOM 3750 C CG . GLN B 2 89 ? 51.818 23.751 105.587 1.00 2.68 ? 89 GLN L CG 1 ATOM 3751 C CD . GLN B 2 89 ? 52.654 24.487 106.631 1.00 5.67 ? 89 GLN L CD 1 ATOM 3752 O OE1 . GLN B 2 89 ? 53.031 25.664 106.543 1.00 7.72 ? 89 GLN L OE1 1 ATOM 3753 N NE2 . GLN B 2 89 ? 52.904 23.824 107.734 1.00 6.33 ? 89 GLN L NE2 1 ATOM 3754 N N . GLN B 2 90 ? 50.273 21.015 105.934 1.00 8.41 ? 90 GLN L N 1 ATOM 3755 C CA . GLN B 2 90 ? 50.338 20.036 107.002 1.00 9.18 ? 90 GLN L CA 1 ATOM 3756 C C . GLN B 2 90 ? 51.570 20.403 107.813 1.00 10.78 ? 90 GLN L C 1 ATOM 3757 O O . GLN B 2 90 ? 52.435 21.096 107.248 1.00 10.79 ? 90 GLN L O 1 ATOM 3758 C CB . GLN B 2 90 ? 50.378 18.726 106.284 1.00 10.98 ? 90 GLN L CB 1 ATOM 3759 C CG . GLN B 2 90 ? 51.039 17.491 106.817 1.00 9.36 ? 90 GLN L CG 1 ATOM 3760 C CD . GLN B 2 90 ? 52.533 17.611 106.644 1.00 11.21 ? 90 GLN L CD 1 ATOM 3761 O OE1 . GLN B 2 90 ? 53.151 17.816 107.676 1.00 13.42 ? 90 GLN L OE1 1 ATOM 3762 N NE2 . GLN B 2 90 ? 53.223 17.596 105.508 1.00 6.93 ? 90 GLN L NE2 1 ATOM 3763 N N . HIS B 2 91 ? 51.680 19.987 109.086 1.00 12.07 ? 91 HIS L N 1 ATOM 3764 C CA . HIS B 2 91 ? 52.826 20.341 109.916 1.00 10.57 ? 91 HIS L CA 1 ATOM 3765 C C . HIS B 2 91 ? 53.368 19.263 110.846 1.00 11.41 ? 91 HIS L C 1 ATOM 3766 O O . HIS B 2 91 ? 53.797 19.515 111.963 1.00 8.89 ? 91 HIS L O 1 ATOM 3767 C CB . HIS B 2 91 ? 52.480 21.624 110.728 1.00 11.10 ? 91 HIS L CB 1 ATOM 3768 C CG . HIS B 2 91 ? 51.584 21.632 111.971 1.00 10.19 ? 91 HIS L CG 1 ATOM 3769 N ND1 . HIS B 2 91 ? 51.838 21.401 113.252 1.00 10.15 ? 91 HIS L ND1 1 ATOM 3770 C CD2 . HIS B 2 91 ? 50.287 22.003 111.906 1.00 9.73 ? 91 HIS L CD2 1 ATOM 3771 C CE1 . HIS B 2 91 ? 50.757 21.617 113.936 1.00 9.54 ? 91 HIS L CE1 1 ATOM 3772 N NE2 . HIS B 2 91 ? 49.831 21.979 113.108 1.00 9.11 ? 91 HIS L NE2 1 ATOM 3773 N N . TYR B 2 92 ? 53.327 18.025 110.391 1.00 14.60 ? 92 TYR L N 1 ATOM 3774 C CA . TYR B 2 92 ? 53.812 16.838 111.095 1.00 16.50 ? 92 TYR L CA 1 ATOM 3775 C C . TYR B 2 92 ? 55.272 16.457 110.796 1.00 19.18 ? 92 TYR L C 1 ATOM 3776 O O . TYR B 2 92 ? 56.107 16.322 111.691 1.00 20.44 ? 92 TYR L O 1 ATOM 3777 C CB . TYR B 2 92 ? 52.842 15.680 110.732 1.00 15.14 ? 92 TYR L CB 1 ATOM 3778 C CG . TYR B 2 92 ? 53.181 14.349 111.330 1.00 14.59 ? 92 TYR L CG 1 ATOM 3779 C CD1 . TYR B 2 92 ? 53.469 14.254 112.648 1.00 15.23 ? 92 TYR L CD1 1 ATOM 3780 C CD2 . TYR B 2 92 ? 53.296 13.257 110.543 1.00 14.56 ? 92 TYR L CD2 1 ATOM 3781 C CE1 . TYR B 2 92 ? 53.905 13.057 113.173 1.00 14.15 ? 92 TYR L CE1 1 ATOM 3782 C CE2 . TYR B 2 92 ? 53.727 12.052 111.052 1.00 15.39 ? 92 TYR L CE2 1 ATOM 3783 C CZ . TYR B 2 92 ? 54.048 11.944 112.382 1.00 15.00 ? 92 TYR L CZ 1 ATOM 3784 O OH . TYR B 2 92 ? 54.561 10.768 112.932 1.00 15.55 ? 92 TYR L OH 1 ATOM 3785 N N . SER B 2 93 ? 55.581 16.249 109.524 1.00 19.81 ? 93 SER L N 1 ATOM 3786 C CA . SER B 2 93 ? 56.900 15.821 109.052 1.00 20.59 ? 93 SER L CA 1 ATOM 3787 C C . SER B 2 93 ? 57.418 16.865 108.090 1.00 18.94 ? 93 SER L C 1 ATOM 3788 O O . SER B 2 93 ? 56.599 17.564 107.509 1.00 19.17 ? 93 SER L O 1 ATOM 3789 C CB . SER B 2 93 ? 56.814 14.519 108.297 1.00 21.69 ? 93 SER L CB 1 ATOM 3790 O OG . SER B 2 93 ? 56.094 13.589 109.102 1.00 27.42 ? 93 SER L OG 1 ATOM 3791 N N . PRO B 2 94 ? 58.686 17.104 107.849 1.00 17.45 ? 94 PRO L N 1 ATOM 3792 C CA . PRO B 2 94 ? 59.100 17.870 106.701 1.00 17.17 ? 94 PRO L CA 1 ATOM 3793 C C . PRO B 2 94 ? 58.935 17.050 105.441 1.00 17.55 ? 94 PRO L C 1 ATOM 3794 O O . PRO B 2 94 ? 58.803 15.824 105.556 1.00 18.71 ? 94 PRO L O 1 ATOM 3795 C CB . PRO B 2 94 ? 60.501 18.247 107.026 1.00 16.21 ? 94 PRO L CB 1 ATOM 3796 C CG . PRO B 2 94 ? 60.442 18.390 108.510 1.00 16.92 ? 94 PRO L CG 1 ATOM 3797 C CD . PRO B 2 94 ? 59.735 17.092 108.842 1.00 17.15 ? 94 PRO L CD 1 ATOM 3798 N N . PRO B 2 95 ? 58.883 17.693 104.244 1.00 16.95 ? 95 PRO L N 1 ATOM 3799 C CA . PRO B 2 95 ? 58.688 19.123 104.094 1.00 15.72 ? 95 PRO L CA 1 ATOM 3800 C C . PRO B 2 95 ? 57.209 19.423 104.253 1.00 14.48 ? 95 PRO L C 1 ATOM 3801 O O . PRO B 2 95 ? 56.347 18.563 103.980 1.00 15.67 ? 95 PRO L O 1 ATOM 3802 C CB . PRO B 2 95 ? 59.262 19.398 102.735 1.00 16.01 ? 95 PRO L CB 1 ATOM 3803 C CG . PRO B 2 95 ? 59.079 18.160 101.898 1.00 17.63 ? 95 PRO L CG 1 ATOM 3804 C CD . PRO B 2 95 ? 58.893 17.051 102.913 1.00 15.92 ? 95 PRO L CD 1 ATOM 3805 N N . TRP B 2 96 ? 56.959 20.661 104.685 1.00 10.05 ? 96 TRP L N 1 ATOM 3806 C CA . TRP B 2 96 ? 55.610 21.108 105.001 1.00 9.37 ? 96 TRP L CA 1 ATOM 3807 C C . TRP B 2 96 ? 54.899 21.320 103.652 1.00 10.54 ? 96 TRP L C 1 ATOM 3808 O O . TRP B 2 96 ? 55.264 22.235 102.909 1.00 13.03 ? 96 TRP L O 1 ATOM 3809 C CB . TRP B 2 96 ? 55.718 22.394 105.810 1.00 9.17 ? 96 TRP L CB 1 ATOM 3810 C CG . TRP B 2 96 ? 56.894 22.384 106.796 1.00 7.02 ? 96 TRP L CG 1 ATOM 3811 C CD1 . TRP B 2 96 ? 57.982 23.208 106.641 1.00 5.85 ? 96 TRP L CD1 1 ATOM 3812 C CD2 . TRP B 2 96 ? 57.017 21.606 107.920 1.00 7.15 ? 96 TRP L CD2 1 ATOM 3813 N NE1 . TRP B 2 96 ? 58.784 22.964 107.659 1.00 6.27 ? 96 TRP L NE1 1 ATOM 3814 C CE2 . TRP B 2 96 ? 58.251 22.025 108.430 1.00 7.23 ? 96 TRP L CE2 1 ATOM 3815 C CE3 . TRP B 2 96 ? 56.279 20.629 108.556 1.00 6.59 ? 96 TRP L CE3 1 ATOM 3816 C CZ2 . TRP B 2 96 ? 58.766 21.503 109.583 1.00 8.78 ? 96 TRP L CZ2 1 ATOM 3817 C CZ3 . TRP B 2 96 ? 56.794 20.111 109.716 1.00 6.41 ? 96 TRP L CZ3 1 ATOM 3818 C CH2 . TRP B 2 96 ? 58.014 20.541 110.210 1.00 7.44 ? 96 TRP L CH2 1 ATOM 3819 N N . THR B 2 97 ? 53.988 20.393 103.270 1.00 9.91 ? 97 THR L N 1 ATOM 3820 C CA . THR B 2 97 ? 53.213 20.357 102.022 1.00 9.87 ? 97 THR L CA 1 ATOM 3821 C C . THR B 2 97 ? 51.797 20.997 102.123 1.00 11.57 ? 97 THR L C 1 ATOM 3822 O O . THR B 2 97 ? 51.061 20.854 103.112 1.00 11.85 ? 97 THR L O 1 ATOM 3823 C CB . THR B 2 97 ? 53.192 18.810 101.518 1.00 11.48 ? 97 THR L CB 1 ATOM 3824 O OG1 . THR B 2 97 ? 52.715 17.952 102.554 1.00 13.30 ? 97 THR L OG1 1 ATOM 3825 C CG2 . THR B 2 97 ? 54.599 18.297 101.143 1.00 12.74 ? 97 THR L CG2 1 ATOM 3826 N N . PHE B 2 98 ? 51.410 21.803 101.132 1.00 12.26 ? 98 PHE L N 1 ATOM 3827 C CA . PHE B 2 98 ? 50.146 22.529 101.127 1.00 12.65 ? 98 PHE L CA 1 ATOM 3828 C C . PHE B 2 98 ? 49.066 21.770 100.323 1.00 14.48 ? 98 PHE L C 1 ATOM 3829 O O . PHE B 2 98 ? 49.240 20.631 99.879 1.00 19.19 ? 98 PHE L O 1 ATOM 3830 C CB . PHE B 2 98 ? 50.403 23.948 100.528 1.00 12.10 ? 98 PHE L CB 1 ATOM 3831 C CG . PHE B 2 98 ? 51.275 24.957 101.323 1.00 9.65 ? 98 PHE L CG 1 ATOM 3832 C CD1 . PHE B 2 98 ? 52.655 24.986 101.174 1.00 8.63 ? 98 PHE L CD1 1 ATOM 3833 C CD2 . PHE B 2 98 ? 50.721 25.859 102.215 1.00 10.67 ? 98 PHE L CD2 1 ATOM 3834 C CE1 . PHE B 2 98 ? 53.468 25.861 101.875 1.00 8.21 ? 98 PHE L CE1 1 ATOM 3835 C CE2 . PHE B 2 98 ? 51.539 26.734 102.916 1.00 11.03 ? 98 PHE L CE2 1 ATOM 3836 C CZ . PHE B 2 98 ? 52.911 26.743 102.756 1.00 8.44 ? 98 PHE L CZ 1 ATOM 3837 N N . GLY B 2 99 ? 47.905 22.350 100.129 1.00 13.64 ? 99 GLY L N 1 ATOM 3838 C CA . GLY B 2 99 ? 46.874 21.769 99.307 1.00 13.70 ? 99 GLY L CA 1 ATOM 3839 C C . GLY B 2 99 ? 46.694 22.693 98.091 1.00 15.58 ? 99 GLY L C 1 ATOM 3840 O O . GLY B 2 99 ? 47.307 23.766 97.947 1.00 18.73 ? 99 GLY L O 1 ATOM 3841 N N . GLY B 2 100 ? 45.768 22.339 97.201 1.00 14.78 ? 100 GLY L N 1 ATOM 3842 C CA . GLY B 2 100 ? 45.539 23.123 96.003 1.00 12.39 ? 100 GLY L CA 1 ATOM 3843 C C . GLY B 2 100 ? 44.740 24.408 96.224 1.00 11.48 ? 100 GLY L C 1 ATOM 3844 O O . GLY B 2 100 ? 44.696 25.279 95.332 1.00 12.42 ? 100 GLY L O 1 ATOM 3845 N N . GLY B 2 101 ? 44.165 24.569 97.432 1.00 10.45 ? 101 GLY L N 1 ATOM 3846 C CA . GLY B 2 101 ? 43.281 25.696 97.654 1.00 8.92 ? 101 GLY L CA 1 ATOM 3847 C C . GLY B 2 101 ? 41.852 25.434 97.248 1.00 8.66 ? 101 GLY L C 1 ATOM 3848 O O . GLY B 2 101 ? 41.490 24.460 96.606 1.00 11.45 ? 101 GLY L O 1 ATOM 3849 N N . THR B 2 102 ? 41.021 26.251 97.826 1.00 5.92 ? 102 THR L N 1 ATOM 3850 C CA . THR B 2 102 ? 39.636 26.244 97.478 1.00 5.65 ? 102 THR L CA 1 ATOM 3851 C C . THR B 2 102 ? 39.250 27.730 97.521 1.00 8.38 ? 102 THR L C 1 ATOM 3852 O O . THR B 2 102 ? 39.636 28.494 98.412 1.00 9.46 ? 102 THR L O 1 ATOM 3853 C CB . THR B 2 102 ? 38.869 25.417 98.488 1.00 2.88 ? 102 THR L CB 1 ATOM 3854 O OG1 . THR B 2 102 ? 39.380 24.099 98.471 1.00 2.00 ? 102 THR L OG1 1 ATOM 3855 C CG2 . THR B 2 102 ? 37.417 25.340 98.138 1.00 2.01 ? 102 THR L CG2 1 ATOM 3856 N N . LYS B 2 103 ? 38.610 28.175 96.435 1.00 13.23 ? 103 LYS L N 1 ATOM 3857 C CA . LYS B 2 103 ? 38.165 29.532 96.252 1.00 17.23 ? 103 LYS L CA 1 ATOM 3858 C C . LYS B 2 103 ? 36.781 29.514 96.850 1.00 17.65 ? 103 LYS L C 1 ATOM 3859 O O . LYS B 2 103 ? 35.991 28.671 96.408 1.00 18.52 ? 103 LYS L O 1 ATOM 3860 C CB . LYS B 2 103 ? 38.084 29.804 94.783 1.00 23.51 ? 103 LYS L CB 1 ATOM 3861 C CG . LYS B 2 103 ? 38.971 30.871 94.194 1.00 28.71 ? 103 LYS L CG 1 ATOM 3862 C CD . LYS B 2 103 ? 38.496 32.245 94.610 1.00 33.60 ? 103 LYS L CD 1 ATOM 3863 C CE . LYS B 2 103 ? 39.404 33.278 93.954 1.00 38.43 ? 103 LYS L CE 1 ATOM 3864 N NZ . LYS B 2 103 ? 38.716 34.551 93.821 1.00 40.38 ? 103 LYS L NZ 1 ATOM 3865 N N . LEU B 2 104 ? 36.447 30.334 97.851 1.00 19.20 ? 104 LEU L N 1 ATOM 3866 C CA . LEU B 2 104 ? 35.083 30.391 98.379 1.00 17.91 ? 104 LEU L CA 1 ATOM 3867 C C . LEU B 2 104 ? 34.497 31.646 97.781 1.00 18.83 ? 104 LEU L C 1 ATOM 3868 O O . LEU B 2 104 ? 35.009 32.731 98.102 1.00 18.38 ? 104 LEU L O 1 ATOM 3869 C CB . LEU B 2 104 ? 35.069 30.511 99.885 1.00 17.35 ? 104 LEU L CB 1 ATOM 3870 C CG . LEU B 2 104 ? 33.842 31.068 100.577 1.00 16.46 ? 104 LEU L CG 1 ATOM 3871 C CD1 . LEU B 2 104 ? 32.594 30.188 100.564 1.00 15.98 ? 104 LEU L CD1 1 ATOM 3872 C CD2 . LEU B 2 104 ? 34.336 31.281 101.974 1.00 14.20 ? 104 LEU L CD2 1 ATOM 3873 N N . GLU B 2 105 ? 33.559 31.412 96.840 1.00 19.27 ? 105 GLU L N 1 ATOM 3874 C CA . GLU B 2 105 ? 32.755 32.386 96.118 1.00 18.85 ? 105 GLU L CA 1 ATOM 3875 C C . GLU B 2 105 ? 31.498 32.633 96.946 1.00 19.23 ? 105 GLU L C 1 ATOM 3876 O O . GLU B 2 105 ? 30.994 31.732 97.652 1.00 20.58 ? 105 GLU L O 1 ATOM 3877 C CB . GLU B 2 105 ? 32.327 31.859 94.742 1.00 18.98 ? 105 GLU L CB 1 ATOM 3878 C CG . GLU B 2 105 ? 31.653 32.900 93.849 1.00 18.56 ? 105 GLU L CG 1 ATOM 3879 C CD . GLU B 2 105 ? 30.345 32.471 93.189 1.00 18.31 ? 105 GLU L CD 1 ATOM 3880 O OE1 . GLU B 2 105 ? 29.313 32.483 93.856 1.00 18.11 ? 105 GLU L OE1 1 ATOM 3881 O OE2 . GLU B 2 105 ? 30.361 32.134 92.007 1.00 18.09 ? 105 GLU L OE2 1 ATOM 3882 N N . ILE B 2 106 ? 30.978 33.863 96.860 1.00 18.80 ? 106 ILE L N 1 ATOM 3883 C CA . ILE B 2 106 ? 29.771 34.260 97.570 1.00 21.52 ? 106 ILE L CA 1 ATOM 3884 C C . ILE B 2 106 ? 28.593 34.248 96.600 1.00 22.43 ? 106 ILE L C 1 ATOM 3885 O O . ILE B 2 106 ? 28.590 35.011 95.628 1.00 22.41 ? 106 ILE L O 1 ATOM 3886 C CB . ILE B 2 106 ? 29.899 35.695 98.157 1.00 22.01 ? 106 ILE L CB 1 ATOM 3887 C CG1 . ILE B 2 106 ? 31.193 35.907 98.918 1.00 25.35 ? 106 ILE L CG1 1 ATOM 3888 C CG2 . ILE B 2 106 ? 28.712 35.928 99.056 1.00 21.77 ? 106 ILE L CG2 1 ATOM 3889 C CD1 . ILE B 2 106 ? 31.399 34.927 100.088 1.00 26.01 ? 106 ILE L CD1 1 ATOM 3890 N N . LYS B 2 107 ? 27.608 33.367 96.780 1.00 24.33 ? 107 LYS L N 1 ATOM 3891 C CA . LYS B 2 107 ? 26.358 33.338 96.009 1.00 23.92 ? 107 LYS L CA 1 ATOM 3892 C C . LYS B 2 107 ? 25.566 34.589 96.380 1.00 25.10 ? 107 LYS L C 1 ATOM 3893 O O . LYS B 2 107 ? 25.359 34.874 97.558 1.00 25.66 ? 107 LYS L O 1 ATOM 3894 C CB . LYS B 2 107 ? 25.597 32.089 96.385 1.00 23.34 ? 107 LYS L CB 1 ATOM 3895 C CG . LYS B 2 107 ? 24.469 31.730 95.439 1.00 22.56 ? 107 LYS L CG 1 ATOM 3896 C CD . LYS B 2 107 ? 23.855 30.400 95.877 1.00 22.18 ? 107 LYS L CD 1 ATOM 3897 C CE . LYS B 2 107 ? 24.864 29.256 95.866 1.00 22.07 ? 107 LYS L CE 1 ATOM 3898 N NZ . LYS B 2 107 ? 25.440 29.076 94.546 1.00 21.87 ? 107 LYS L NZ 1 ATOM 3899 N N . ARG B 2 108 ? 25.066 35.302 95.385 1.00 28.24 ? 108 ARG L N 1 ATOM 3900 C CA . ARG B 2 108 ? 24.515 36.656 95.499 1.00 30.99 ? 108 ARG L CA 1 ATOM 3901 C C . ARG B 2 108 ? 23.150 36.628 94.834 1.00 31.03 ? 108 ARG L C 1 ATOM 3902 O O . ARG B 2 108 ? 22.728 35.614 94.291 1.00 31.48 ? 108 ARG L O 1 ATOM 3903 C CB . ARG B 2 108 ? 25.432 37.660 94.735 1.00 32.67 ? 108 ARG L CB 1 ATOM 3904 C CG . ARG B 2 108 ? 25.532 39.093 95.220 1.00 34.24 ? 108 ARG L CG 1 ATOM 3905 C CD . ARG B 2 108 ? 25.563 40.193 94.159 1.00 33.74 ? 108 ARG L CD 1 ATOM 3906 N NE . ARG B 2 108 ? 24.223 40.469 93.672 1.00 36.29 ? 108 ARG L NE 1 ATOM 3907 C CZ . ARG B 2 108 ? 23.597 41.648 93.742 1.00 39.22 ? 108 ARG L CZ 1 ATOM 3908 N NH1 . ARG B 2 108 ? 24.154 42.730 94.281 1.00 41.73 ? 108 ARG L NH1 1 ATOM 3909 N NH2 . ARG B 2 108 ? 22.368 41.756 93.234 1.00 44.30 ? 108 ARG L NH2 1 ATOM 3910 N N . ALA B 2 109 ? 22.396 37.703 94.794 1.00 30.92 ? 109 ALA L N 1 ATOM 3911 C CA . ALA B 2 109 ? 21.163 37.705 94.012 1.00 30.66 ? 109 ALA L CA 1 ATOM 3912 C C . ALA B 2 109 ? 21.554 38.016 92.570 1.00 30.63 ? 109 ALA L C 1 ATOM 3913 O O . ALA B 2 109 ? 22.631 38.579 92.361 1.00 32.47 ? 109 ALA L O 1 ATOM 3914 C CB . ALA B 2 109 ? 20.227 38.791 94.484 1.00 30.46 ? 109 ALA L CB 1 ATOM 3915 N N . ASP B 2 110 ? 20.787 37.692 91.534 1.00 30.03 ? 110 ASP L N 1 ATOM 3916 C CA . ASP B 2 110 ? 21.227 38.069 90.201 1.00 30.73 ? 110 ASP L CA 1 ATOM 3917 C C . ASP B 2 110 ? 21.087 39.566 89.955 1.00 33.10 ? 110 ASP L C 1 ATOM 3918 O O . ASP B 2 110 ? 20.149 40.261 90.378 1.00 36.00 ? 110 ASP L O 1 ATOM 3919 C CB . ASP B 2 110 ? 20.450 37.316 89.139 1.00 31.16 ? 110 ASP L CB 1 ATOM 3920 C CG . ASP B 2 110 ? 20.570 35.785 89.183 1.00 31.19 ? 110 ASP L CG 1 ATOM 3921 O OD1 . ASP B 2 110 ? 21.382 35.210 89.952 1.00 30.65 ? 110 ASP L OD1 1 ATOM 3922 O OD2 . ASP B 2 110 ? 19.798 35.176 88.424 1.00 33.13 ? 110 ASP L OD2 1 ATOM 3923 N N . ALA B 2 111 ? 22.104 40.027 89.238 1.00 34.05 ? 111 ALA L N 1 ATOM 3924 C CA . ALA B 2 111 ? 22.316 41.419 88.933 1.00 35.59 ? 111 ALA L CA 1 ATOM 3925 C C . ALA B 2 111 ? 22.705 41.425 87.486 1.00 35.69 ? 111 ALA L C 1 ATOM 3926 O O . ALA B 2 111 ? 23.390 40.536 86.984 1.00 39.76 ? 111 ALA L O 1 ATOM 3927 C CB . ALA B 2 111 ? 23.462 41.989 89.728 1.00 34.86 ? 111 ALA L CB 1 ATOM 3928 N N . ALA B 2 112 ? 22.258 42.454 86.800 1.00 32.76 ? 112 ALA L N 1 ATOM 3929 C CA . ALA B 2 112 ? 22.436 42.536 85.364 1.00 30.70 ? 112 ALA L CA 1 ATOM 3930 C C . ALA B 2 112 ? 23.435 43.634 85.057 1.00 29.58 ? 112 ALA L C 1 ATOM 3931 O O . ALA B 2 112 ? 23.589 44.609 85.828 1.00 30.04 ? 112 ALA L O 1 ATOM 3932 C CB . ALA B 2 112 ? 21.113 42.864 84.655 1.00 28.81 ? 112 ALA L CB 1 ATOM 3933 N N . PRO B 2 113 ? 24.176 43.406 83.957 1.00 27.48 ? 113 PRO L N 1 ATOM 3934 C CA . PRO B 2 113 ? 25.285 44.256 83.629 1.00 25.30 ? 113 PRO L CA 1 ATOM 3935 C C . PRO B 2 113 ? 24.888 45.675 83.212 1.00 23.65 ? 113 PRO L C 1 ATOM 3936 O O . PRO B 2 113 ? 23.794 45.969 82.715 1.00 24.29 ? 113 PRO L O 1 ATOM 3937 C CB . PRO B 2 113 ? 26.004 43.415 82.588 1.00 26.31 ? 113 PRO L CB 1 ATOM 3938 C CG . PRO B 2 113 ? 24.914 42.676 81.877 1.00 25.70 ? 113 PRO L CG 1 ATOM 3939 C CD . PRO B 2 113 ? 24.123 42.234 83.064 1.00 26.12 ? 113 PRO L CD 1 ATOM 3940 N N . THR B 2 114 ? 25.834 46.566 83.516 1.00 21.99 ? 114 THR L N 1 ATOM 3941 C CA . THR B 2 114 ? 25.845 47.973 83.117 1.00 19.81 ? 114 THR L CA 1 ATOM 3942 C C . THR B 2 114 ? 26.932 48.038 82.042 1.00 18.29 ? 114 THR L C 1 ATOM 3943 O O . THR B 2 114 ? 28.116 47.907 82.350 1.00 17.45 ? 114 THR L O 1 ATOM 3944 C CB . THR B 2 114 ? 26.125 48.696 84.431 1.00 21.03 ? 114 THR L CB 1 ATOM 3945 O OG1 . THR B 2 114 ? 24.919 48.479 85.172 1.00 20.42 ? 114 THR L OG1 1 ATOM 3946 C CG2 . THR B 2 114 ? 26.549 50.153 84.297 1.00 21.31 ? 114 THR L CG2 1 ATOM 3947 N N . VAL B 2 115 ? 26.498 48.208 80.796 1.00 18.08 ? 115 VAL L N 1 ATOM 3948 C CA . VAL B 2 115 ? 27.291 48.044 79.573 1.00 18.64 ? 115 VAL L CA 1 ATOM 3949 C C . VAL B 2 115 ? 27.697 49.406 79.004 1.00 18.80 ? 115 VAL L C 1 ATOM 3950 O O . VAL B 2 115 ? 26.822 50.249 78.811 1.00 18.53 ? 115 VAL L O 1 ATOM 3951 C CB . VAL B 2 115 ? 26.438 47.258 78.528 1.00 17.43 ? 115 VAL L CB 1 ATOM 3952 C CG1 . VAL B 2 115 ? 27.356 46.750 77.457 1.00 19.00 ? 115 VAL L CG1 1 ATOM 3953 C CG2 . VAL B 2 115 ? 25.737 46.059 79.112 1.00 15.80 ? 115 VAL L CG2 1 ATOM 3954 N N . SER B 2 116 ? 28.963 49.655 78.707 1.00 19.52 ? 116 SER L N 1 ATOM 3955 C CA . SER B 2 116 ? 29.400 50.940 78.204 1.00 22.53 ? 116 SER L CA 1 ATOM 3956 C C . SER B 2 116 ? 30.330 50.697 77.056 1.00 24.74 ? 116 SER L C 1 ATOM 3957 O O . SER B 2 116 ? 31.350 50.037 77.248 1.00 27.22 ? 116 SER L O 1 ATOM 3958 C CB . SER B 2 116 ? 30.181 51.747 79.226 1.00 23.68 ? 116 SER L CB 1 ATOM 3959 O OG . SER B 2 116 ? 29.330 52.275 80.236 1.00 27.09 ? 116 SER L OG 1 ATOM 3960 N N . ILE B 2 117 ? 29.994 51.180 75.854 1.00 25.88 ? 117 ILE L N 1 ATOM 3961 C CA . ILE B 2 117 ? 30.842 50.997 74.680 1.00 25.67 ? 117 ILE L CA 1 ATOM 3962 C C . ILE B 2 117 ? 31.503 52.368 74.577 1.00 24.80 ? 117 ILE L C 1 ATOM 3963 O O . ILE B 2 117 ? 30.930 53.422 74.934 1.00 25.13 ? 117 ILE L O 1 ATOM 3964 C CB . ILE B 2 117 ? 29.958 50.611 73.416 1.00 25.00 ? 117 ILE L CB 1 ATOM 3965 C CG1 . ILE B 2 117 ? 30.889 50.400 72.267 1.00 24.93 ? 117 ILE L CG1 1 ATOM 3966 C CG2 . ILE B 2 117 ? 28.901 51.656 73.060 1.00 26.28 ? 117 ILE L CG2 1 ATOM 3967 C CD1 . ILE B 2 117 ? 30.121 49.956 71.021 1.00 24.43 ? 117 ILE L CD1 1 ATOM 3968 N N . PHE B 2 118 ? 32.784 52.319 74.238 1.00 25.28 ? 118 PHE L N 1 ATOM 3969 C CA . PHE B 2 118 ? 33.538 53.544 74.108 1.00 26.68 ? 118 PHE L CA 1 ATOM 3970 C C . PHE B 2 118 ? 34.185 53.603 72.757 1.00 27.59 ? 118 PHE L C 1 ATOM 3971 O O . PHE B 2 118 ? 34.831 52.636 72.356 1.00 29.38 ? 118 PHE L O 1 ATOM 3972 C CB . PHE B 2 118 ? 34.621 53.624 75.126 1.00 27.39 ? 118 PHE L CB 1 ATOM 3973 C CG . PHE B 2 118 ? 34.113 54.009 76.492 1.00 27.20 ? 118 PHE L CG 1 ATOM 3974 C CD1 . PHE B 2 118 ? 33.849 55.342 76.768 1.00 28.21 ? 118 PHE L CD1 1 ATOM 3975 C CD2 . PHE B 2 118 ? 33.972 53.041 77.460 1.00 25.84 ? 118 PHE L CD2 1 ATOM 3976 C CE1 . PHE B 2 118 ? 33.441 55.723 78.025 1.00 27.11 ? 118 PHE L CE1 1 ATOM 3977 C CE2 . PHE B 2 118 ? 33.574 53.436 78.717 1.00 25.26 ? 118 PHE L CE2 1 ATOM 3978 C CZ . PHE B 2 118 ? 33.313 54.766 79.004 1.00 26.50 ? 118 PHE L CZ 1 ATOM 3979 N N . PRO B 2 119 ? 33.979 54.672 71.995 1.00 27.96 ? 119 PRO L N 1 ATOM 3980 C CA . PRO B 2 119 ? 34.813 55.081 70.873 1.00 28.92 ? 119 PRO L CA 1 ATOM 3981 C C . PRO B 2 119 ? 36.326 55.165 71.120 1.00 30.48 ? 119 PRO L C 1 ATOM 3982 O O . PRO B 2 119 ? 36.800 55.542 72.204 1.00 32.04 ? 119 PRO L O 1 ATOM 3983 C CB . PRO B 2 119 ? 34.240 56.401 70.482 1.00 27.73 ? 119 PRO L CB 1 ATOM 3984 C CG . PRO B 2 119 ? 33.764 56.925 71.827 1.00 28.24 ? 119 PRO L CG 1 ATOM 3985 C CD . PRO B 2 119 ? 32.988 55.697 72.268 1.00 28.73 ? 119 PRO L CD 1 ATOM 3986 N N . PRO B 2 120 ? 37.095 54.864 70.074 1.00 29.95 ? 120 PRO L N 1 ATOM 3987 C CA . PRO B 2 120 ? 38.485 55.237 69.948 1.00 29.31 ? 120 PRO L CA 1 ATOM 3988 C C . PRO B 2 120 ? 38.718 56.684 70.272 1.00 28.95 ? 120 PRO L C 1 ATOM 3989 O O . PRO B 2 120 ? 37.983 57.577 69.878 1.00 30.36 ? 120 PRO L O 1 ATOM 3990 C CB . PRO B 2 120 ? 38.817 54.892 68.537 1.00 28.82 ? 120 PRO L CB 1 ATOM 3991 C CG . PRO B 2 120 ? 37.975 53.650 68.311 1.00 28.59 ? 120 PRO L CG 1 ATOM 3992 C CD . PRO B 2 120 ? 36.667 54.035 68.950 1.00 28.40 ? 120 PRO L CD 1 ATOM 3993 N N . SER B 2 121 ? 39.742 56.887 71.065 1.00 29.77 ? 121 SER L N 1 ATOM 3994 C CA . SER B 2 121 ? 40.224 58.195 71.484 1.00 30.68 ? 121 SER L CA 1 ATOM 3995 C C . SER B 2 121 ? 40.848 58.912 70.293 1.00 32.38 ? 121 SER L C 1 ATOM 3996 O O . SER B 2 121 ? 41.601 58.277 69.546 1.00 32.26 ? 121 SER L O 1 ATOM 3997 C CB . SER B 2 121 ? 41.245 57.944 72.595 1.00 30.55 ? 121 SER L CB 1 ATOM 3998 O OG . SER B 2 121 ? 41.926 59.082 73.087 1.00 31.92 ? 121 SER L OG 1 ATOM 3999 N N . SER B 2 122 ? 40.659 60.207 70.098 1.00 33.87 ? 122 SER L N 1 ATOM 4000 C CA . SER B 2 122 ? 41.242 60.867 68.953 1.00 36.01 ? 122 SER L CA 1 ATOM 4001 C C . SER B 2 122 ? 42.756 60.674 68.915 1.00 36.41 ? 122 SER L C 1 ATOM 4002 O O . SER B 2 122 ? 43.330 60.313 67.876 1.00 36.73 ? 122 SER L O 1 ATOM 4003 C CB . SER B 2 122 ? 40.869 62.350 69.014 1.00 37.69 ? 122 SER L CB 1 ATOM 4004 O OG . SER B 2 122 ? 40.542 62.799 70.335 1.00 40.36 ? 122 SER L OG 1 ATOM 4005 N N . GLU B 2 123 ? 43.382 60.767 70.101 1.00 35.99 ? 123 GLU L N 1 ATOM 4006 C CA . GLU B 2 123 ? 44.823 60.601 70.229 1.00 34.10 ? 123 GLU L CA 1 ATOM 4007 C C . GLU B 2 123 ? 45.241 59.191 69.845 1.00 31.21 ? 123 GLU L C 1 ATOM 4008 O O . GLU B 2 123 ? 46.280 59.028 69.194 1.00 29.35 ? 123 GLU L O 1 ATOM 4009 C CB . GLU B 2 123 ? 45.338 60.893 71.655 1.00 36.96 ? 123 GLU L CB 1 ATOM 4010 C CG . GLU B 2 123 ? 44.420 60.734 72.881 1.00 39.70 ? 123 GLU L CG 1 ATOM 4011 C CD . GLU B 2 123 ? 43.579 61.970 73.262 1.00 41.96 ? 123 GLU L CD 1 ATOM 4012 O OE1 . GLU B 2 123 ? 44.188 62.927 73.754 1.00 41.81 ? 123 GLU L OE1 1 ATOM 4013 O OE2 . GLU B 2 123 ? 42.343 61.982 73.090 1.00 43.49 ? 123 GLU L OE2 1 ATOM 4014 N N . GLN B 2 124 ? 44.456 58.150 70.128 1.00 28.21 ? 124 GLN L N 1 ATOM 4015 C CA . GLN B 2 124 ? 44.841 56.835 69.654 1.00 25.47 ? 124 GLN L CA 1 ATOM 4016 C C . GLN B 2 124 ? 44.706 56.787 68.124 1.00 26.28 ? 124 GLN L C 1 ATOM 4017 O O . GLN B 2 124 ? 45.601 56.300 67.406 1.00 25.47 ? 124 GLN L O 1 ATOM 4018 C CB . GLN B 2 124 ? 43.963 55.806 70.275 1.00 22.95 ? 124 GLN L CB 1 ATOM 4019 C CG . GLN B 2 124 ? 44.639 54.494 70.026 1.00 20.24 ? 124 GLN L CG 1 ATOM 4020 C CD . GLN B 2 124 ? 43.774 53.329 70.414 1.00 18.44 ? 124 GLN L CD 1 ATOM 4021 O OE1 . GLN B 2 124 ? 42.563 53.461 70.635 1.00 14.06 ? 124 GLN L OE1 1 ATOM 4022 N NE2 . GLN B 2 124 ? 44.403 52.166 70.526 1.00 18.75 ? 124 GLN L NE2 1 ATOM 4023 N N . LEU B 2 125 ? 43.626 57.407 67.623 1.00 28.05 ? 125 LEU L N 1 ATOM 4024 C CA . LEU B 2 125 ? 43.373 57.491 66.196 1.00 28.42 ? 125 LEU L CA 1 ATOM 4025 C C . LEU B 2 125 ? 44.507 58.196 65.510 1.00 28.67 ? 125 LEU L C 1 ATOM 4026 O O . LEU B 2 125 ? 44.907 57.746 64.447 1.00 28.72 ? 125 LEU L O 1 ATOM 4027 C CB . LEU B 2 125 ? 42.086 58.235 65.904 1.00 29.12 ? 125 LEU L CB 1 ATOM 4028 C CG . LEU B 2 125 ? 40.856 57.356 66.089 1.00 29.55 ? 125 LEU L CG 1 ATOM 4029 C CD1 . LEU B 2 125 ? 39.638 58.257 66.317 1.00 29.84 ? 125 LEU L CD1 1 ATOM 4030 C CD2 . LEU B 2 125 ? 40.747 56.385 64.917 1.00 27.64 ? 125 LEU L CD2 1 ATOM 4031 N N . THR B 2 126 ? 45.111 59.186 66.173 1.00 29.16 ? 126 THR L N 1 ATOM 4032 C CA . THR B 2 126 ? 46.276 59.900 65.657 1.00 31.30 ? 126 THR L CA 1 ATOM 4033 C C . THR B 2 126 ? 47.435 58.926 65.504 1.00 33.47 ? 126 THR L C 1 ATOM 4034 O O . THR B 2 126 ? 48.207 59.015 64.553 1.00 33.43 ? 126 THR L O 1 ATOM 4035 C CB . THR B 2 126 ? 46.672 61.055 66.633 1.00 31.97 ? 126 THR L CB 1 ATOM 4036 O OG1 . THR B 2 126 ? 45.549 61.925 66.577 1.00 32.31 ? 126 THR L OG1 1 ATOM 4037 C CG2 . THR B 2 126 ? 47.950 61.831 66.308 1.00 32.73 ? 126 THR L CG2 1 ATOM 4038 N N . SER B 2 127 ? 47.534 57.934 66.371 1.00 35.04 ? 127 SER L N 1 ATOM 4039 C CA . SER B 2 127 ? 48.636 57.002 66.280 1.00 34.66 ? 127 SER L CA 1 ATOM 4040 C C . SER B 2 127 ? 48.343 55.865 65.305 1.00 33.41 ? 127 SER L C 1 ATOM 4041 O O . SER B 2 127 ? 49.085 54.879 65.214 1.00 34.18 ? 127 SER L O 1 ATOM 4042 C CB . SER B 2 127 ? 48.906 56.518 67.696 1.00 36.61 ? 127 SER L CB 1 ATOM 4043 O OG . SER B 2 127 ? 48.954 57.653 68.576 1.00 38.64 ? 127 SER L OG 1 ATOM 4044 N N . GLY B 2 128 ? 47.239 55.961 64.573 1.00 31.31 ? 128 GLY L N 1 ATOM 4045 C CA . GLY B 2 128 ? 46.969 55.006 63.522 1.00 29.51 ? 128 GLY L CA 1 ATOM 4046 C C . GLY B 2 128 ? 46.292 53.724 63.990 1.00 29.54 ? 128 GLY L C 1 ATOM 4047 O O . GLY B 2 128 ? 46.049 52.823 63.152 1.00 31.79 ? 128 GLY L O 1 ATOM 4048 N N . GLY B 2 129 ? 45.886 53.665 65.278 1.00 27.76 ? 129 GLY L N 1 ATOM 4049 C CA . GLY B 2 129 ? 45.186 52.506 65.824 1.00 25.07 ? 129 GLY L CA 1 ATOM 4050 C C . GLY B 2 129 ? 43.891 52.954 66.468 1.00 23.60 ? 129 GLY L C 1 ATOM 4051 O O . GLY B 2 129 ? 43.792 54.100 66.905 1.00 23.68 ? 129 GLY L O 1 ATOM 4052 N N . ALA B 2 130 ? 42.889 52.096 66.517 1.00 21.90 ? 130 ALA L N 1 ATOM 4053 C CA . ALA B 2 130 ? 41.610 52.396 67.126 1.00 21.38 ? 130 ALA L CA 1 ATOM 4054 C C . ALA B 2 130 ? 41.377 51.334 68.194 1.00 20.98 ? 130 ALA L C 1 ATOM 4055 O O . ALA B 2 130 ? 41.870 50.226 67.999 1.00 20.94 ? 130 ALA L O 1 ATOM 4056 C CB . ALA B 2 130 ? 40.500 52.286 66.091 1.00 20.24 ? 130 ALA L CB 1 ATOM 4057 N N . SER B 2 131 ? 40.722 51.592 69.333 1.00 22.51 ? 131 SER L N 1 ATOM 4058 C CA . SER B 2 131 ? 40.323 50.550 70.259 1.00 21.87 ? 131 SER L CA 1 ATOM 4059 C C . SER B 2 131 ? 38.912 50.854 70.785 1.00 22.21 ? 131 SER L C 1 ATOM 4060 O O . SER B 2 131 ? 38.586 51.942 71.283 1.00 22.08 ? 131 SER L O 1 ATOM 4061 C CB . SER B 2 131 ? 41.323 50.452 71.428 1.00 21.54 ? 131 SER L CB 1 ATOM 4062 O OG . SER B 2 131 ? 42.626 49.963 71.128 1.00 19.06 ? 131 SER L OG 1 ATOM 4063 N N . VAL B 2 132 ? 37.999 49.920 70.611 1.00 23.79 ? 132 VAL L N 1 ATOM 4064 C CA . VAL B 2 132 ? 36.663 50.110 71.115 1.00 24.86 ? 132 VAL L CA 1 ATOM 4065 C C . VAL B 2 132 ? 36.696 49.374 72.460 1.00 25.58 ? 132 VAL L C 1 ATOM 4066 O O . VAL B 2 132 ? 37.244 48.265 72.570 1.00 26.08 ? 132 VAL L O 1 ATOM 4067 C CB . VAL B 2 132 ? 35.668 49.503 70.111 1.00 26.21 ? 132 VAL L CB 1 ATOM 4068 C CG1 . VAL B 2 132 ? 34.255 49.954 70.488 1.00 27.35 ? 132 VAL L CG1 1 ATOM 4069 C CG2 . VAL B 2 132 ? 35.985 49.972 68.682 1.00 26.39 ? 132 VAL L CG2 1 ATOM 4070 N N . VAL B 2 133 ? 36.133 49.957 73.520 1.00 25.04 ? 133 VAL L N 1 ATOM 4071 C CA . VAL B 2 133 ? 36.221 49.438 74.867 1.00 22.90 ? 133 VAL L CA 1 ATOM 4072 C C . VAL B 2 133 ? 34.805 49.351 75.398 1.00 22.51 ? 133 VAL L C 1 ATOM 4073 O O . VAL B 2 133 ? 34.046 50.323 75.507 1.00 19.72 ? 133 VAL L O 1 ATOM 4074 C CB . VAL B 2 133 ? 37.091 50.405 75.678 1.00 22.49 ? 133 VAL L CB 1 ATOM 4075 C CG1 . VAL B 2 133 ? 36.926 50.192 77.157 1.00 21.15 ? 133 VAL L CG1 1 ATOM 4076 C CG2 . VAL B 2 133 ? 38.536 50.130 75.398 1.00 22.40 ? 133 VAL L CG2 1 ATOM 4077 N N . CYS B 2 134 ? 34.453 48.117 75.647 1.00 22.62 ? 134 CYS L N 1 ATOM 4078 C CA . CYS B 2 134 ? 33.181 47.835 76.243 1.00 22.83 ? 134 CYS L CA 1 ATOM 4079 C C . CYS B 2 134 ? 33.467 47.448 77.686 1.00 21.22 ? 134 CYS L C 1 ATOM 4080 O O . CYS B 2 134 ? 34.393 46.655 77.937 1.00 20.05 ? 134 CYS L O 1 ATOM 4081 C CB . CYS B 2 134 ? 32.523 46.695 75.529 1.00 25.30 ? 134 CYS L CB 1 ATOM 4082 S SG . CYS B 2 134 ? 30.768 46.649 75.919 1.00 31.11 ? 134 CYS L SG 1 ATOM 4083 N N . PHE B 2 135 ? 32.722 48.068 78.607 1.00 18.82 ? 135 PHE L N 1 ATOM 4084 C CA . PHE B 2 135 ? 32.753 47.848 80.034 1.00 14.06 ? 135 PHE L CA 1 ATOM 4085 C C . PHE B 2 135 ? 31.464 47.134 80.397 1.00 11.31 ? 135 PHE L C 1 ATOM 4086 O O . PHE B 2 135 ? 30.393 47.503 79.919 1.00 9.84 ? 135 PHE L O 1 ATOM 4087 C CB . PHE B 2 135 ? 32.841 49.185 80.730 1.00 12.26 ? 135 PHE L CB 1 ATOM 4088 C CG . PHE B 2 135 ? 34.239 49.782 80.746 1.00 10.12 ? 135 PHE L CG 1 ATOM 4089 C CD1 . PHE B 2 135 ? 35.369 48.984 80.761 1.00 8.94 ? 135 PHE L CD1 1 ATOM 4090 C CD2 . PHE B 2 135 ? 34.391 51.142 80.791 1.00 9.44 ? 135 PHE L CD2 1 ATOM 4091 C CE1 . PHE B 2 135 ? 36.630 49.539 80.826 1.00 7.09 ? 135 PHE L CE1 1 ATOM 4092 C CE2 . PHE B 2 135 ? 35.660 51.703 80.857 1.00 8.59 ? 135 PHE L CE2 1 ATOM 4093 C CZ . PHE B 2 135 ? 36.784 50.907 80.873 1.00 7.69 ? 135 PHE L CZ 1 ATOM 4094 N N . LEU B 2 136 ? 31.506 46.016 81.100 1.00 12.15 ? 136 LEU L N 1 ATOM 4095 C CA . LEU B 2 136 ? 30.298 45.353 81.595 1.00 14.94 ? 136 LEU L CA 1 ATOM 4096 C C . LEU B 2 136 ? 30.387 45.167 83.118 1.00 15.41 ? 136 LEU L C 1 ATOM 4097 O O . LEU B 2 136 ? 30.932 44.203 83.659 1.00 18.00 ? 136 LEU L O 1 ATOM 4098 C CB . LEU B 2 136 ? 30.159 44.037 80.912 1.00 14.95 ? 136 LEU L CB 1 ATOM 4099 C CG . LEU B 2 136 ? 29.987 44.181 79.426 1.00 16.08 ? 136 LEU L CG 1 ATOM 4100 C CD1 . LEU B 2 136 ? 31.070 43.395 78.681 1.00 16.86 ? 136 LEU L CD1 1 ATOM 4101 C CD2 . LEU B 2 136 ? 28.574 43.755 79.096 1.00 15.89 ? 136 LEU L CD2 1 ATOM 4102 N N . ASN B 2 137 ? 29.883 46.154 83.845 1.00 13.94 ? 137 ASN L N 1 ATOM 4103 C CA . ASN B 2 137 ? 30.034 46.192 85.269 1.00 11.65 ? 137 ASN L CA 1 ATOM 4104 C C . ASN B 2 137 ? 28.854 45.708 86.053 1.00 13.57 ? 137 ASN L C 1 ATOM 4105 O O . ASN B 2 137 ? 27.689 45.895 85.702 1.00 16.89 ? 137 ASN L O 1 ATOM 4106 C CB . ASN B 2 137 ? 30.329 47.598 85.722 1.00 8.61 ? 137 ASN L CB 1 ATOM 4107 C CG . ASN B 2 137 ? 31.411 48.320 84.957 1.00 5.10 ? 137 ASN L CG 1 ATOM 4108 O OD1 . ASN B 2 137 ? 31.095 49.255 84.229 1.00 3.85 ? 137 ASN L OD1 1 ATOM 4109 N ND2 . ASN B 2 137 ? 32.663 47.902 85.088 1.00 4.70 ? 137 ASN L ND2 1 ATOM 4110 N N . ASN B 2 138 ? 29.249 45.090 87.149 1.00 15.81 ? 138 ASN L N 1 ATOM 4111 C CA . ASN B 2 138 ? 28.351 44.672 88.230 1.00 18.65 ? 138 ASN L CA 1 ATOM 4112 C C . ASN B 2 138 ? 27.210 43.700 87.946 1.00 20.06 ? 138 ASN L C 1 ATOM 4113 O O . ASN B 2 138 ? 26.056 43.864 88.353 1.00 22.17 ? 138 ASN L O 1 ATOM 4114 C CB . ASN B 2 138 ? 27.757 45.923 88.905 1.00 19.87 ? 138 ASN L CB 1 ATOM 4115 C CG . ASN B 2 138 ? 28.849 46.778 89.540 1.00 21.52 ? 138 ASN L CG 1 ATOM 4116 O OD1 . ASN B 2 138 ? 29.388 46.516 90.635 1.00 19.73 ? 138 ASN L OD1 1 ATOM 4117 N ND2 . ASN B 2 138 ? 29.179 47.852 88.815 1.00 23.86 ? 138 ASN L ND2 1 ATOM 4118 N N . PHE B 2 139 ? 27.603 42.602 87.309 1.00 19.33 ? 139 PHE L N 1 ATOM 4119 C CA . PHE B 2 139 ? 26.703 41.533 86.954 1.00 18.12 ? 139 PHE L CA 1 ATOM 4120 C C . PHE B 2 139 ? 27.005 40.368 87.900 1.00 16.76 ? 139 PHE L C 1 ATOM 4121 O O . PHE B 2 139 ? 28.099 40.275 88.484 1.00 17.91 ? 139 PHE L O 1 ATOM 4122 C CB . PHE B 2 139 ? 26.932 41.180 85.453 1.00 18.74 ? 139 PHE L CB 1 ATOM 4123 C CG . PHE B 2 139 ? 28.342 40.757 85.051 1.00 19.43 ? 139 PHE L CG 1 ATOM 4124 C CD1 . PHE B 2 139 ? 28.765 39.447 85.237 1.00 19.01 ? 139 PHE L CD1 1 ATOM 4125 C CD2 . PHE B 2 139 ? 29.217 41.695 84.546 1.00 20.68 ? 139 PHE L CD2 1 ATOM 4126 C CE1 . PHE B 2 139 ? 30.053 39.062 84.939 1.00 20.45 ? 139 PHE L CE1 1 ATOM 4127 C CE2 . PHE B 2 139 ? 30.512 41.307 84.244 1.00 22.19 ? 139 PHE L CE2 1 ATOM 4128 C CZ . PHE B 2 139 ? 30.930 40.002 84.440 1.00 22.50 ? 139 PHE L CZ 1 ATOM 4129 N N . TYR B 2 140 ? 26.002 39.496 87.996 1.00 16.96 ? 140 TYR L N 1 ATOM 4130 C CA . TYR B 2 140 ? 25.967 38.319 88.842 1.00 18.11 ? 140 TYR L CA 1 ATOM 4131 C C . TYR B 2 140 ? 24.823 37.466 88.316 1.00 18.30 ? 140 TYR L C 1 ATOM 4132 O O . TYR B 2 140 ? 23.695 37.951 88.271 1.00 18.33 ? 140 TYR L O 1 ATOM 4133 C CB . TYR B 2 140 ? 25.667 38.639 90.321 1.00 18.20 ? 140 TYR L CB 1 ATOM 4134 C CG . TYR B 2 140 ? 25.898 37.368 91.083 1.00 18.90 ? 140 TYR L CG 1 ATOM 4135 C CD1 . TYR B 2 140 ? 27.180 37.062 91.451 1.00 18.66 ? 140 TYR L CD1 1 ATOM 4136 C CD2 . TYR B 2 140 ? 24.862 36.477 91.260 1.00 20.17 ? 140 TYR L CD2 1 ATOM 4137 C CE1 . TYR B 2 140 ? 27.435 35.822 91.982 1.00 19.29 ? 140 TYR L CE1 1 ATOM 4138 C CE2 . TYR B 2 140 ? 25.096 35.245 91.782 1.00 20.30 ? 140 TYR L CE2 1 ATOM 4139 C CZ . TYR B 2 140 ? 26.384 34.933 92.129 1.00 19.73 ? 140 TYR L CZ 1 ATOM 4140 O OH . TYR B 2 140 ? 26.636 33.654 92.583 1.00 21.18 ? 140 TYR L OH 1 ATOM 4141 N N . PRO B 2 141 ? 24.906 36.201 87.913 1.00 20.03 ? 141 PRO L N 1 ATOM 4142 C CA . PRO B 2 141 ? 26.077 35.332 87.846 1.00 21.99 ? 141 PRO L CA 1 ATOM 4143 C C . PRO B 2 141 ? 27.364 35.754 87.179 1.00 24.59 ? 141 PRO L C 1 ATOM 4144 O O . PRO B 2 141 ? 27.500 36.792 86.555 1.00 25.54 ? 141 PRO L O 1 ATOM 4145 C CB . PRO B 2 141 ? 25.551 34.066 87.206 1.00 21.01 ? 141 PRO L CB 1 ATOM 4146 C CG . PRO B 2 141 ? 24.141 34.011 87.707 1.00 22.71 ? 141 PRO L CG 1 ATOM 4147 C CD . PRO B 2 141 ? 23.735 35.456 87.462 1.00 21.42 ? 141 PRO L CD 1 ATOM 4148 N N . LYS B 2 142 ? 28.308 34.850 87.332 1.00 28.54 ? 142 LYS L N 1 ATOM 4149 C CA . LYS B 2 142 ? 29.638 35.004 86.818 1.00 31.99 ? 142 LYS L CA 1 ATOM 4150 C C . LYS B 2 142 ? 29.704 35.110 85.303 1.00 34.43 ? 142 LYS L C 1 ATOM 4151 O O . LYS B 2 142 ? 30.447 35.930 84.786 1.00 36.21 ? 142 LYS L O 1 ATOM 4152 C CB . LYS B 2 142 ? 30.384 33.811 87.340 1.00 31.93 ? 142 LYS L CB 1 ATOM 4153 C CG . LYS B 2 142 ? 31.849 34.036 87.508 1.00 33.35 ? 142 LYS L CG 1 ATOM 4154 C CD . LYS B 2 142 ? 32.706 33.939 86.255 1.00 35.58 ? 142 LYS L CD 1 ATOM 4155 C CE . LYS B 2 142 ? 34.125 33.539 86.689 1.00 37.17 ? 142 LYS L CE 1 ATOM 4156 N NZ . LYS B 2 142 ? 34.155 32.253 87.399 1.00 37.24 ? 142 LYS L NZ 1 ATOM 4157 N N . ASP B 2 143 ? 28.914 34.286 84.615 1.00 36.19 ? 143 ASP L N 1 ATOM 4158 C CA . ASP B 2 143 ? 29.032 34.053 83.179 1.00 37.13 ? 143 ASP L CA 1 ATOM 4159 C C . ASP B 2 143 ? 28.215 34.983 82.288 1.00 36.41 ? 143 ASP L C 1 ATOM 4160 O O . ASP B 2 143 ? 26.981 35.023 82.375 1.00 38.18 ? 143 ASP L O 1 ATOM 4161 C CB . ASP B 2 143 ? 28.644 32.579 82.886 1.00 39.77 ? 143 ASP L CB 1 ATOM 4162 C CG . ASP B 2 143 ? 29.144 31.570 83.934 1.00 41.46 ? 143 ASP L CG 1 ATOM 4163 O OD1 . ASP B 2 143 ? 30.356 31.522 84.189 1.00 42.63 ? 143 ASP L OD1 1 ATOM 4164 O OD2 . ASP B 2 143 ? 28.321 30.844 84.506 1.00 41.97 ? 143 ASP L OD2 1 ATOM 4165 N N . ILE B 2 144 ? 28.919 35.683 81.404 1.00 33.68 ? 144 ILE L N 1 ATOM 4166 C CA . ILE B 2 144 ? 28.316 36.594 80.464 1.00 32.00 ? 144 ILE L CA 1 ATOM 4167 C C . ILE B 2 144 ? 29.118 36.416 79.195 1.00 31.79 ? 144 ILE L C 1 ATOM 4168 O O . ILE B 2 144 ? 30.348 36.417 79.266 1.00 31.49 ? 144 ILE L O 1 ATOM 4169 C CB . ILE B 2 144 ? 28.395 38.052 81.041 1.00 31.03 ? 144 ILE L CB 1 ATOM 4170 C CG1 . ILE B 2 144 ? 27.755 39.023 80.057 1.00 29.93 ? 144 ILE L CG1 1 ATOM 4171 C CG2 . ILE B 2 144 ? 29.833 38.467 81.321 1.00 31.58 ? 144 ILE L CG2 1 ATOM 4172 C CD1 . ILE B 2 144 ? 27.561 40.451 80.614 1.00 28.41 ? 144 ILE L CD1 1 ATOM 4173 N N . ASN B 2 145 ? 28.538 36.153 78.030 1.00 31.99 ? 145 ASN L N 1 ATOM 4174 C CA . ASN B 2 145 ? 29.349 36.076 76.821 1.00 30.76 ? 145 ASN L CA 1 ATOM 4175 C C . ASN B 2 145 ? 29.272 37.416 76.090 1.00 27.96 ? 145 ASN L C 1 ATOM 4176 O O . ASN B 2 145 ? 28.197 38.008 75.963 1.00 28.70 ? 145 ASN L O 1 ATOM 4177 C CB . ASN B 2 145 ? 28.865 34.949 75.887 1.00 33.60 ? 145 ASN L CB 1 ATOM 4178 C CG . ASN B 2 145 ? 29.903 34.649 74.778 1.00 35.98 ? 145 ASN L CG 1 ATOM 4179 O OD1 . ASN B 2 145 ? 30.609 33.631 74.806 1.00 35.92 ? 145 ASN L OD1 1 ATOM 4180 N ND2 . ASN B 2 145 ? 30.050 35.500 73.753 1.00 36.82 ? 145 ASN L ND2 1 ATOM 4181 N N . VAL B 2 146 ? 30.378 37.968 75.620 1.00 25.72 ? 146 VAL L N 1 ATOM 4182 C CA . VAL B 2 146 ? 30.264 39.214 74.911 1.00 25.79 ? 146 VAL L CA 1 ATOM 4183 C C . VAL B 2 146 ? 30.763 38.899 73.488 1.00 27.43 ? 146 VAL L C 1 ATOM 4184 O O . VAL B 2 146 ? 31.715 38.112 73.309 1.00 30.09 ? 146 VAL L O 1 ATOM 4185 C CB . VAL B 2 146 ? 31.111 40.347 75.626 1.00 24.84 ? 146 VAL L CB 1 ATOM 4186 C CG1 . VAL B 2 146 ? 30.765 40.327 77.103 1.00 24.02 ? 146 VAL L CG1 1 ATOM 4187 C CG2 . VAL B 2 146 ? 32.602 40.154 75.563 1.00 25.18 ? 146 VAL L CG2 1 ATOM 4188 N N . LYS B 2 147 ? 30.072 39.367 72.435 1.00 28.79 ? 147 LYS L N 1 ATOM 4189 C CA . LYS B 2 147 ? 30.487 39.203 71.050 1.00 28.25 ? 147 LYS L CA 1 ATOM 4190 C C . LYS B 2 147 ? 30.659 40.606 70.488 1.00 28.44 ? 147 LYS L C 1 ATOM 4191 O O . LYS B 2 147 ? 30.038 41.576 70.957 1.00 29.13 ? 147 LYS L O 1 ATOM 4192 C CB . LYS B 2 147 ? 29.432 38.453 70.238 1.00 27.77 ? 147 LYS L CB 1 ATOM 4193 C CG . LYS B 2 147 ? 29.216 37.030 70.745 1.00 27.17 ? 147 LYS L CG 1 ATOM 4194 C CD . LYS B 2 147 ? 28.412 36.156 69.800 1.00 26.76 ? 147 LYS L CD 1 ATOM 4195 C CE . LYS B 2 147 ? 26.938 36.509 69.692 1.00 26.38 ? 147 LYS L CE 1 ATOM 4196 N NZ . LYS B 2 147 ? 26.305 35.592 68.764 1.00 26.43 ? 147 LYS L NZ 1 ATOM 4197 N N . TRP B 2 148 ? 31.563 40.784 69.541 1.00 28.71 ? 148 TRP L N 1 ATOM 4198 C CA . TRP B 2 148 ? 31.690 42.090 68.920 1.00 28.81 ? 148 TRP L CA 1 ATOM 4199 C C . TRP B 2 148 ? 31.060 42.022 67.544 1.00 30.04 ? 148 TRP L C 1 ATOM 4200 O O . TRP B 2 148 ? 31.038 40.936 66.966 1.00 29.07 ? 148 TRP L O 1 ATOM 4201 C CB . TRP B 2 148 ? 33.146 42.459 68.834 1.00 26.88 ? 148 TRP L CB 1 ATOM 4202 C CG . TRP B 2 148 ? 33.481 43.034 70.184 1.00 25.78 ? 148 TRP L CG 1 ATOM 4203 C CD1 . TRP B 2 148 ? 33.775 42.221 71.225 1.00 25.87 ? 148 TRP L CD1 1 ATOM 4204 C CD2 . TRP B 2 148 ? 33.517 44.366 70.505 1.00 25.23 ? 148 TRP L CD2 1 ATOM 4205 N NE1 . TRP B 2 148 ? 34.003 43.036 72.217 1.00 26.19 ? 148 TRP L NE1 1 ATOM 4206 C CE2 . TRP B 2 148 ? 33.857 44.314 71.832 1.00 24.40 ? 148 TRP L CE2 1 ATOM 4207 C CE3 . TRP B 2 148 ? 33.316 45.588 69.893 1.00 24.72 ? 148 TRP L CE3 1 ATOM 4208 C CZ2 . TRP B 2 148 ? 34.009 45.480 72.549 1.00 23.25 ? 148 TRP L CZ2 1 ATOM 4209 C CZ3 . TRP B 2 148 ? 33.470 46.745 70.619 1.00 23.22 ? 148 TRP L CZ3 1 ATOM 4210 C CH2 . TRP B 2 148 ? 33.810 46.701 71.942 1.00 23.57 ? 148 TRP L CH2 1 ATOM 4211 N N . LYS B 2 149 ? 30.468 43.097 67.025 1.00 31.36 ? 149 LYS L N 1 ATOM 4212 C CA . LYS B 2 149 ? 29.846 43.097 65.713 1.00 31.82 ? 149 LYS L CA 1 ATOM 4213 C C . LYS B 2 149 ? 30.107 44.414 65.060 1.00 32.39 ? 149 LYS L C 1 ATOM 4214 O O . LYS B 2 149 ? 29.583 45.467 65.458 1.00 34.72 ? 149 LYS L O 1 ATOM 4215 C CB . LYS B 2 149 ? 28.348 42.912 65.777 1.00 32.72 ? 149 LYS L CB 1 ATOM 4216 C CG . LYS B 2 149 ? 28.021 41.490 66.099 1.00 34.95 ? 149 LYS L CG 1 ATOM 4217 C CD . LYS B 2 149 ? 26.556 41.217 66.041 1.00 39.73 ? 149 LYS L CD 1 ATOM 4218 C CE . LYS B 2 149 ? 26.482 39.722 66.322 1.00 45.10 ? 149 LYS L CE 1 ATOM 4219 N NZ . LYS B 2 149 ? 25.117 39.233 66.350 1.00 47.44 ? 149 LYS L NZ 1 ATOM 4220 N N . ILE B 2 150 ? 30.964 44.288 64.064 1.00 32.04 ? 150 ILE L N 1 ATOM 4221 C CA . ILE B 2 150 ? 31.362 45.429 63.272 1.00 30.97 ? 150 ILE L CA 1 ATOM 4222 C C . ILE B 2 150 ? 30.511 45.266 62.034 1.00 30.81 ? 150 ILE L C 1 ATOM 4223 O O . ILE B 2 150 ? 30.656 44.301 61.281 1.00 31.32 ? 150 ILE L O 1 ATOM 4224 C CB . ILE B 2 150 ? 32.840 45.427 62.803 1.00 30.44 ? 150 ILE L CB 1 ATOM 4225 C CG1 . ILE B 2 150 ? 33.869 45.210 63.902 1.00 30.47 ? 150 ILE L CG1 1 ATOM 4226 C CG2 . ILE B 2 150 ? 33.015 46.795 62.147 1.00 29.99 ? 150 ILE L CG2 1 ATOM 4227 C CD1 . ILE B 2 150 ? 35.333 45.223 63.383 1.00 30.55 ? 150 ILE L CD1 1 ATOM 4228 N N . ASP B 2 151 ? 29.584 46.196 61.907 1.00 30.49 ? 151 ASP L N 1 ATOM 4229 C CA . ASP B 2 151 ? 28.654 46.231 60.801 1.00 31.09 ? 151 ASP L CA 1 ATOM 4230 C C . ASP B 2 151 ? 27.925 44.888 60.569 1.00 33.17 ? 151 ASP L C 1 ATOM 4231 O O . ASP B 2 151 ? 27.952 44.317 59.468 1.00 36.91 ? 151 ASP L O 1 ATOM 4232 C CB . ASP B 2 151 ? 29.444 46.710 59.533 1.00 28.36 ? 151 ASP L CB 1 ATOM 4233 C CG . ASP B 2 151 ? 29.395 48.219 59.281 1.00 27.07 ? 151 ASP L CG 1 ATOM 4234 O OD1 . ASP B 2 151 ? 28.405 48.682 58.718 1.00 27.79 ? 151 ASP L OD1 1 ATOM 4235 O OD2 . ASP B 2 151 ? 30.320 48.935 59.648 1.00 25.10 ? 151 ASP L OD2 1 ATOM 4236 N N . GLY B 2 152 ? 27.336 44.285 61.627 1.00 34.33 ? 152 GLY L N 1 ATOM 4237 C CA . GLY B 2 152 ? 26.557 43.042 61.530 1.00 35.24 ? 152 GLY L CA 1 ATOM 4238 C C . GLY B 2 152 ? 27.446 41.803 61.488 1.00 36.33 ? 152 GLY L C 1 ATOM 4239 O O . GLY B 2 152 ? 27.080 40.696 61.875 1.00 37.48 ? 152 GLY L O 1 ATOM 4240 N N . SER B 2 153 ? 28.667 41.981 61.027 1.00 37.31 ? 153 SER L N 1 ATOM 4241 C CA . SER B 2 153 ? 29.635 40.924 60.941 1.00 37.24 ? 153 SER L CA 1 ATOM 4242 C C . SER B 2 153 ? 30.156 40.836 62.367 1.00 37.26 ? 153 SER L C 1 ATOM 4243 O O . SER B 2 153 ? 30.602 41.835 62.956 1.00 36.91 ? 153 SER L O 1 ATOM 4244 C CB . SER B 2 153 ? 30.745 41.329 59.950 1.00 37.66 ? 153 SER L CB 1 ATOM 4245 O OG . SER B 2 153 ? 30.256 41.922 58.729 1.00 39.70 ? 153 SER L OG 1 ATOM 4246 N N . GLU B 2 154 ? 29.932 39.643 62.936 1.00 37.65 ? 154 GLU L N 1 ATOM 4247 C CA . GLU B 2 154 ? 30.501 39.249 64.216 1.00 36.21 ? 154 GLU L CA 1 ATOM 4248 C C . GLU B 2 154 ? 32.037 39.386 64.141 1.00 37.89 ? 154 GLU L C 1 ATOM 4249 O O . GLU B 2 154 ? 32.691 38.832 63.247 1.00 39.19 ? 154 GLU L O 1 ATOM 4250 C CB . GLU B 2 154 ? 30.140 37.809 64.502 1.00 33.43 ? 154 GLU L CB 1 ATOM 4251 C CG . GLU B 2 154 ? 29.513 37.653 65.873 1.00 30.56 ? 154 GLU L CG 1 ATOM 4252 C CD . GLU B 2 154 ? 29.078 36.228 66.161 1.00 29.36 ? 154 GLU L CD 1 ATOM 4253 O OE1 . GLU B 2 154 ? 27.941 35.879 65.853 1.00 28.88 ? 154 GLU L OE1 1 ATOM 4254 O OE2 . GLU B 2 154 ? 29.882 35.474 66.707 1.00 28.94 ? 154 GLU L OE2 1 ATOM 4255 N N . ARG B 2 155 ? 32.687 40.180 64.965 1.00 38.79 ? 155 ARG L N 1 ATOM 4256 C CA . ARG B 2 155 ? 34.121 40.211 65.013 1.00 39.39 ? 155 ARG L CA 1 ATOM 4257 C C . ARG B 2 155 ? 34.458 39.121 66.034 1.00 39.52 ? 155 ARG L C 1 ATOM 4258 O O . ARG B 2 155 ? 33.839 39.048 67.112 1.00 41.74 ? 155 ARG L O 1 ATOM 4259 C CB . ARG B 2 155 ? 34.493 41.611 65.443 1.00 39.64 ? 155 ARG L CB 1 ATOM 4260 C CG . ARG B 2 155 ? 35.959 41.888 65.381 1.00 41.69 ? 155 ARG L CG 1 ATOM 4261 C CD . ARG B 2 155 ? 36.493 41.446 64.042 1.00 44.50 ? 155 ARG L CD 1 ATOM 4262 N NE . ARG B 2 155 ? 37.824 41.970 63.923 1.00 48.64 ? 155 ARG L NE 1 ATOM 4263 C CZ . ARG B 2 155 ? 38.150 42.763 62.915 1.00 51.26 ? 155 ARG L CZ 1 ATOM 4264 N NH1 . ARG B 2 155 ? 37.275 43.040 61.937 1.00 53.15 ? 155 ARG L NH1 1 ATOM 4265 N NH2 . ARG B 2 155 ? 39.398 43.215 62.890 1.00 51.17 ? 155 ARG L NH2 1 ATOM 4266 N N . GLN B 2 156 ? 35.337 38.179 65.711 1.00 38.58 ? 156 GLN L N 1 ATOM 4267 C CA . GLN B 2 156 ? 35.681 37.156 66.677 1.00 38.36 ? 156 GLN L CA 1 ATOM 4268 C C . GLN B 2 156 ? 37.174 37.166 66.896 1.00 40.73 ? 156 GLN L C 1 ATOM 4269 O O . GLN B 2 156 ? 37.733 36.349 67.633 1.00 45.15 ? 156 GLN L O 1 ATOM 4270 C CB . GLN B 2 156 ? 35.203 35.797 66.174 1.00 34.45 ? 156 GLN L CB 1 ATOM 4271 C CG . GLN B 2 156 ? 33.901 35.439 66.883 1.00 31.10 ? 156 GLN L CG 1 ATOM 4272 C CD . GLN B 2 156 ? 33.152 34.263 66.282 1.00 29.54 ? 156 GLN L CD 1 ATOM 4273 O OE1 . GLN B 2 156 ? 33.207 33.130 66.744 1.00 28.75 ? 156 GLN L OE1 1 ATOM 4274 N NE2 . GLN B 2 156 ? 32.406 34.489 65.214 1.00 28.82 ? 156 GLN L NE2 1 ATOM 4275 N N . ASN B 2 157 ? 37.869 38.119 66.286 1.00 42.06 ? 157 ASN L N 1 ATOM 4276 C CA . ASN B 2 157 ? 39.318 38.202 66.404 1.00 42.94 ? 157 ASN L CA 1 ATOM 4277 C C . ASN B 2 157 ? 39.745 39.619 66.760 1.00 41.62 ? 157 ASN L C 1 ATOM 4278 O O . ASN B 2 157 ? 39.125 40.559 66.252 1.00 44.84 ? 157 ASN L O 1 ATOM 4279 C CB . ASN B 2 157 ? 40.028 37.775 65.083 1.00 46.95 ? 157 ASN L CB 1 ATOM 4280 C CG . ASN B 2 157 ? 39.268 37.924 63.760 1.00 50.83 ? 157 ASN L CG 1 ATOM 4281 O OD1 . ASN B 2 157 ? 38.095 38.331 63.709 1.00 54.17 ? 157 ASN L OD1 1 ATOM 4282 N ND2 . ASN B 2 157 ? 39.857 37.575 62.628 1.00 52.06 ? 157 ASN L ND2 1 ATOM 4283 N N . GLY B 2 158 ? 40.719 39.760 67.692 1.00 39.62 ? 158 GLY L N 1 ATOM 4284 C CA . GLY B 2 158 ? 41.284 41.063 68.080 1.00 36.80 ? 158 GLY L CA 1 ATOM 4285 C C . GLY B 2 158 ? 40.846 41.627 69.450 1.00 35.73 ? 158 GLY L C 1 ATOM 4286 O O . GLY B 2 158 ? 41.166 42.765 69.833 1.00 36.04 ? 158 GLY L O 1 ATOM 4287 N N . VAL B 2 159 ? 40.208 40.767 70.238 1.00 34.71 ? 159 VAL L N 1 ATOM 4288 C CA . VAL B 2 159 ? 39.563 41.164 71.462 1.00 31.92 ? 159 VAL L CA 1 ATOM 4289 C C . VAL B 2 159 ? 40.314 40.652 72.673 1.00 31.31 ? 159 VAL L C 1 ATOM 4290 O O . VAL B 2 159 ? 40.665 39.469 72.712 1.00 32.16 ? 159 VAL L O 1 ATOM 4291 C CB . VAL B 2 159 ? 38.148 40.620 71.295 1.00 30.39 ? 159 VAL L CB 1 ATOM 4292 C CG1 . VAL B 2 159 ? 37.556 40.048 72.578 1.00 30.50 ? 159 VAL L CG1 1 ATOM 4293 C CG2 . VAL B 2 159 ? 37.334 41.789 70.749 1.00 28.65 ? 159 VAL L CG2 1 ATOM 4294 N N . LEU B 2 160 ? 40.583 41.494 73.657 1.00 31.27 ? 160 LEU L N 1 ATOM 4295 C CA . LEU B 2 160 ? 41.207 41.024 74.868 1.00 29.95 ? 160 LEU L CA 1 ATOM 4296 C C . LEU B 2 160 ? 40.081 41.159 75.873 1.00 29.87 ? 160 LEU L C 1 ATOM 4297 O O . LEU B 2 160 ? 39.301 42.123 75.884 1.00 30.28 ? 160 LEU L O 1 ATOM 4298 C CB . LEU B 2 160 ? 42.381 41.891 75.291 1.00 28.35 ? 160 LEU L CB 1 ATOM 4299 C CG . LEU B 2 160 ? 43.595 42.034 74.407 1.00 27.55 ? 160 LEU L CG 1 ATOM 4300 C CD1 . LEU B 2 160 ? 43.266 42.900 73.176 1.00 28.29 ? 160 LEU L CD1 1 ATOM 4301 C CD2 . LEU B 2 160 ? 44.698 42.669 75.251 1.00 27.35 ? 160 LEU L CD2 1 ATOM 4302 N N . ASN B 2 161 ? 40.019 40.131 76.712 1.00 30.08 ? 161 ASN L N 1 ATOM 4303 C CA . ASN B 2 161 ? 38.937 40.006 77.655 1.00 31.78 ? 161 ASN L CA 1 ATOM 4304 C C . ASN B 2 161 ? 39.381 39.926 79.110 1.00 32.48 ? 161 ASN L C 1 ATOM 4305 O O . ASN B 2 161 ? 39.938 38.889 79.490 1.00 34.95 ? 161 ASN L O 1 ATOM 4306 C CB . ASN B 2 161 ? 38.150 38.775 77.251 1.00 31.32 ? 161 ASN L CB 1 ATOM 4307 C CG . ASN B 2 161 ? 36.991 39.156 76.370 1.00 30.25 ? 161 ASN L CG 1 ATOM 4308 O OD1 . ASN B 2 161 ? 36.393 40.216 76.536 1.00 29.75 ? 161 ASN L OD1 1 ATOM 4309 N ND2 . ASN B 2 161 ? 36.620 38.312 75.415 1.00 31.91 ? 161 ASN L ND2 1 ATOM 4310 N N . SER B 2 162 ? 39.211 40.977 79.929 1.00 32.14 ? 162 SER L N 1 ATOM 4311 C CA . SER B 2 162 ? 39.579 40.947 81.340 1.00 32.55 ? 162 SER L CA 1 ATOM 4312 C C . SER B 2 162 ? 38.383 41.029 82.269 1.00 33.98 ? 162 SER L C 1 ATOM 4313 O O . SER B 2 162 ? 37.469 41.836 82.085 1.00 35.58 ? 162 SER L O 1 ATOM 4314 C CB . SER B 2 162 ? 40.512 42.093 81.653 1.00 30.07 ? 162 SER L CB 1 ATOM 4315 O OG . SER B 2 162 ? 41.151 41.940 82.917 1.00 28.38 ? 162 SER L OG 1 ATOM 4316 N N . TRP B 2 163 ? 38.436 40.201 83.299 1.00 36.95 ? 163 TRP L N 1 ATOM 4317 C CA . TRP B 2 163 ? 37.365 40.100 84.260 1.00 38.16 ? 163 TRP L CA 1 ATOM 4318 C C . TRP B 2 163 ? 37.963 40.513 85.575 1.00 35.98 ? 163 TRP L C 1 ATOM 4319 O O . TRP B 2 163 ? 39.122 40.267 85.888 1.00 36.49 ? 163 TRP L O 1 ATOM 4320 C CB . TRP B 2 163 ? 36.839 38.685 84.487 1.00 43.92 ? 163 TRP L CB 1 ATOM 4321 C CG . TRP B 2 163 ? 36.588 37.796 83.262 1.00 48.80 ? 163 TRP L CG 1 ATOM 4322 C CD1 . TRP B 2 163 ? 35.308 37.532 82.855 1.00 50.11 ? 163 TRP L CD1 1 ATOM 4323 C CD2 . TRP B 2 163 ? 37.541 37.159 82.480 1.00 50.52 ? 163 TRP L CD2 1 ATOM 4324 N NE1 . TRP B 2 163 ? 35.443 36.738 81.820 1.00 51.33 ? 163 TRP L NE1 1 ATOM 4325 C CE2 . TRP B 2 163 ? 36.744 36.490 81.557 1.00 51.63 ? 163 TRP L CE2 1 ATOM 4326 C CE3 . TRP B 2 163 ? 38.929 37.038 82.387 1.00 51.40 ? 163 TRP L CE3 1 ATOM 4327 C CZ2 . TRP B 2 163 ? 37.309 35.705 80.554 1.00 52.58 ? 163 TRP L CZ2 1 ATOM 4328 C CZ3 . TRP B 2 163 ? 39.493 36.249 81.388 1.00 52.88 ? 163 TRP L CZ3 1 ATOM 4329 C CH2 . TRP B 2 163 ? 38.691 35.585 80.478 1.00 53.22 ? 163 TRP L CH2 1 ATOM 4330 N N . THR B 2 164 ? 37.192 41.225 86.345 1.00 32.78 ? 164 THR L N 1 ATOM 4331 C CA . THR B 2 164 ? 37.528 41.538 87.715 1.00 30.33 ? 164 THR L CA 1 ATOM 4332 C C . THR B 2 164 ? 37.257 40.269 88.540 1.00 30.82 ? 164 THR L C 1 ATOM 4333 O O . THR B 2 164 ? 36.461 39.403 88.141 1.00 30.67 ? 164 THR L O 1 ATOM 4334 C CB . THR B 2 164 ? 36.633 42.735 88.059 1.00 29.32 ? 164 THR L CB 1 ATOM 4335 O OG1 . THR B 2 164 ? 37.189 43.812 87.328 1.00 30.32 ? 164 THR L OG1 1 ATOM 4336 C CG2 . THR B 2 164 ? 36.543 43.086 89.526 1.00 30.30 ? 164 THR L CG2 1 ATOM 4337 N N . ASP B 2 165 ? 37.923 40.157 89.699 1.00 32.04 ? 165 ASP L N 1 ATOM 4338 C CA . ASP B 2 165 ? 37.703 39.050 90.632 1.00 32.47 ? 165 ASP L CA 1 ATOM 4339 C C . ASP B 2 165 ? 36.364 39.242 91.338 1.00 31.94 ? 165 ASP L C 1 ATOM 4340 O O . ASP B 2 165 ? 35.678 40.228 91.032 1.00 33.22 ? 165 ASP L O 1 ATOM 4341 C CB . ASP B 2 165 ? 38.814 39.018 91.670 1.00 33.64 ? 165 ASP L CB 1 ATOM 4342 C CG . ASP B 2 165 ? 39.329 37.624 92.020 1.00 36.17 ? 165 ASP L CG 1 ATOM 4343 O OD1 . ASP B 2 165 ? 38.644 36.631 91.744 1.00 36.06 ? 165 ASP L OD1 1 ATOM 4344 O OD2 . ASP B 2 165 ? 40.436 37.544 92.568 1.00 39.56 ? 165 ASP L OD2 1 ATOM 4345 N N . GLN B 2 166 ? 35.925 38.420 92.297 1.00 30.37 ? 166 GLN L N 1 ATOM 4346 C CA . GLN B 2 166 ? 34.600 38.697 92.828 1.00 27.85 ? 166 GLN L CA 1 ATOM 4347 C C . GLN B 2 166 ? 34.763 39.838 93.816 1.00 28.43 ? 166 GLN L C 1 ATOM 4348 O O . GLN B 2 166 ? 35.777 39.946 94.523 1.00 29.57 ? 166 GLN L O 1 ATOM 4349 C CB . GLN B 2 166 ? 33.977 37.490 93.540 1.00 27.57 ? 166 GLN L CB 1 ATOM 4350 C CG . GLN B 2 166 ? 32.524 37.867 93.773 1.00 26.43 ? 166 GLN L CG 1 ATOM 4351 C CD . GLN B 2 166 ? 31.607 36.767 94.233 1.00 25.59 ? 166 GLN L CD 1 ATOM 4352 O OE1 . GLN B 2 166 ? 31.998 35.836 94.946 1.00 27.07 ? 166 GLN L OE1 1 ATOM 4353 N NE2 . GLN B 2 166 ? 30.354 36.891 93.813 1.00 26.00 ? 166 GLN L NE2 1 ATOM 4354 N N . ASP B 2 167 ? 33.804 40.754 93.768 1.00 27.77 ? 167 ASP L N 1 ATOM 4355 C CA . ASP B 2 167 ? 33.812 41.833 94.707 1.00 27.07 ? 167 ASP L CA 1 ATOM 4356 C C . ASP B 2 167 ? 33.316 41.398 96.075 1.00 26.64 ? 167 ASP L C 1 ATOM 4357 O O . ASP B 2 167 ? 32.347 40.668 96.299 1.00 25.73 ? 167 ASP L O 1 ATOM 4358 C CB . ASP B 2 167 ? 32.973 42.975 94.167 1.00 28.63 ? 167 ASP L CB 1 ATOM 4359 C CG . ASP B 2 167 ? 33.069 44.230 95.036 1.00 30.65 ? 167 ASP L CG 1 ATOM 4360 O OD1 . ASP B 2 167 ? 34.169 44.536 95.512 1.00 33.51 ? 167 ASP L OD1 1 ATOM 4361 O OD2 . ASP B 2 167 ? 32.043 44.892 95.253 1.00 30.61 ? 167 ASP L OD2 1 ATOM 4362 N N . SER B 2 168 ? 34.084 41.942 96.995 1.00 25.91 ? 168 SER L N 1 ATOM 4363 C CA . SER B 2 168 ? 33.940 41.733 98.406 1.00 26.35 ? 168 SER L CA 1 ATOM 4364 C C . SER B 2 168 ? 33.189 42.878 99.044 1.00 25.72 ? 168 SER L C 1 ATOM 4365 O O . SER B 2 168 ? 33.540 43.325 100.129 1.00 26.48 ? 168 SER L O 1 ATOM 4366 C CB . SER B 2 168 ? 35.351 41.585 98.958 1.00 27.36 ? 168 SER L CB 1 ATOM 4367 O OG . SER B 2 168 ? 36.197 42.684 98.597 1.00 29.87 ? 168 SER L OG 1 ATOM 4368 N N . LYS B 2 169 ? 32.252 43.498 98.349 1.00 24.42 ? 169 LYS L N 1 ATOM 4369 C CA . LYS B 2 169 ? 31.369 44.467 98.972 1.00 23.98 ? 169 LYS L CA 1 ATOM 4370 C C . LYS B 2 169 ? 30.123 43.987 98.279 1.00 23.17 ? 169 LYS L C 1 ATOM 4371 O O . LYS B 2 169 ? 29.569 43.010 98.778 1.00 22.09 ? 169 LYS L O 1 ATOM 4372 C CB . LYS B 2 169 ? 31.770 45.909 98.612 1.00 25.56 ? 169 LYS L CB 1 ATOM 4373 C CG . LYS B 2 169 ? 32.884 46.335 99.594 1.00 27.94 ? 169 LYS L CG 1 ATOM 4374 C CD . LYS B 2 169 ? 33.599 47.676 99.375 1.00 32.21 ? 169 LYS L CD 1 ATOM 4375 C CE . LYS B 2 169 ? 34.505 47.630 98.145 1.00 35.29 ? 169 LYS L CE 1 ATOM 4376 N NZ . LYS B 2 169 ? 34.007 48.421 97.022 1.00 40.37 ? 169 LYS L NZ 1 ATOM 4377 N N . ASP B 2 170 ? 29.667 44.504 97.145 1.00 23.45 ? 170 ASP L N 1 ATOM 4378 C CA . ASP B 2 170 ? 28.536 43.866 96.499 1.00 22.81 ? 170 ASP L CA 1 ATOM 4379 C C . ASP B 2 170 ? 29.108 42.657 95.786 1.00 21.88 ? 170 ASP L C 1 ATOM 4380 O O . ASP B 2 170 ? 30.030 42.838 94.990 1.00 23.29 ? 170 ASP L O 1 ATOM 4381 C CB . ASP B 2 170 ? 27.863 44.823 95.513 1.00 23.32 ? 170 ASP L CB 1 ATOM 4382 C CG . ASP B 2 170 ? 28.774 45.668 94.631 1.00 23.76 ? 170 ASP L CG 1 ATOM 4383 O OD1 . ASP B 2 170 ? 29.419 45.113 93.738 1.00 23.16 ? 170 ASP L OD1 1 ATOM 4384 O OD2 . ASP B 2 170 ? 28.810 46.888 94.824 1.00 25.38 ? 170 ASP L OD2 1 ATOM 4385 N N . SER B 2 171 ? 28.662 41.434 95.997 1.00 21.67 ? 171 SER L N 1 ATOM 4386 C CA . SER B 2 171 ? 29.371 40.307 95.417 1.00 20.99 ? 171 SER L CA 1 ATOM 4387 C C . SER B 2 171 ? 29.216 40.103 93.895 1.00 21.53 ? 171 SER L C 1 ATOM 4388 O O . SER B 2 171 ? 28.660 39.108 93.427 1.00 22.84 ? 171 SER L O 1 ATOM 4389 C CB . SER B 2 171 ? 28.929 39.131 96.311 1.00 18.99 ? 171 SER L CB 1 ATOM 4390 O OG . SER B 2 171 ? 28.983 39.497 97.702 1.00 18.67 ? 171 SER L OG 1 ATOM 4391 N N . THR B 2 172 ? 29.751 41.009 93.082 1.00 19.91 ? 172 THR L N 1 ATOM 4392 C CA . THR B 2 172 ? 29.538 41.004 91.649 1.00 17.57 ? 172 THR L CA 1 ATOM 4393 C C . THR B 2 172 ? 30.839 40.873 90.852 1.00 18.28 ? 172 THR L C 1 ATOM 4394 O O . THR B 2 172 ? 31.920 40.894 91.460 1.00 19.58 ? 172 THR L O 1 ATOM 4395 C CB . THR B 2 172 ? 28.838 42.300 91.326 1.00 17.04 ? 172 THR L CB 1 ATOM 4396 O OG1 . THR B 2 172 ? 29.825 43.311 91.548 1.00 18.12 ? 172 THR L OG1 1 ATOM 4397 C CG2 . THR B 2 172 ? 27.583 42.543 92.159 1.00 16.12 ? 172 THR L CG2 1 ATOM 4398 N N . TYR B 2 173 ? 30.795 40.723 89.515 1.00 17.84 ? 173 TYR L N 1 ATOM 4399 C CA . TYR B 2 173 ? 32.008 40.705 88.693 1.00 17.67 ? 173 TYR L CA 1 ATOM 4400 C C . TYR B 2 173 ? 31.927 41.809 87.638 1.00 18.11 ? 173 TYR L C 1 ATOM 4401 O O . TYR B 2 173 ? 30.877 42.449 87.502 1.00 17.28 ? 173 TYR L O 1 ATOM 4402 C CB . TYR B 2 173 ? 32.156 39.368 87.987 1.00 17.12 ? 173 TYR L CB 1 ATOM 4403 C CG . TYR B 2 173 ? 31.921 38.171 88.877 1.00 17.68 ? 173 TYR L CG 1 ATOM 4404 C CD1 . TYR B 2 173 ? 30.624 37.807 89.130 1.00 18.38 ? 173 TYR L CD1 1 ATOM 4405 C CD2 . TYR B 2 173 ? 32.991 37.489 89.419 1.00 18.29 ? 173 TYR L CD2 1 ATOM 4406 C CE1 . TYR B 2 173 ? 30.386 36.739 89.943 1.00 18.95 ? 173 TYR L CE1 1 ATOM 4407 C CE2 . TYR B 2 173 ? 32.754 36.408 90.244 1.00 18.53 ? 173 TYR L CE2 1 ATOM 4408 C CZ . TYR B 2 173 ? 31.441 36.031 90.505 1.00 19.55 ? 173 TYR L CZ 1 ATOM 4409 O OH . TYR B 2 173 ? 31.155 34.928 91.322 1.00 21.58 ? 173 TYR L OH 1 ATOM 4410 N N . SER B 2 174 ? 32.962 42.090 86.854 1.00 18.68 ? 174 SER L N 1 ATOM 4411 C CA . SER B 2 174 ? 32.937 43.157 85.871 1.00 21.37 ? 174 SER L CA 1 ATOM 4412 C C . SER B 2 174 ? 33.855 42.788 84.717 1.00 22.49 ? 174 SER L C 1 ATOM 4413 O O . SER B 2 174 ? 34.896 42.196 84.972 1.00 24.56 ? 174 SER L O 1 ATOM 4414 C CB . SER B 2 174 ? 33.370 44.434 86.576 1.00 23.59 ? 174 SER L CB 1 ATOM 4415 O OG . SER B 2 174 ? 32.473 44.839 87.628 1.00 26.35 ? 174 SER L OG 1 ATOM 4416 N N . MET B 2 175 ? 33.592 43.078 83.459 1.00 21.58 ? 175 MET L N 1 ATOM 4417 C CA . MET B 2 175 ? 34.461 42.658 82.368 1.00 20.03 ? 175 MET L CA 1 ATOM 4418 C C . MET B 2 175 ? 34.913 43.814 81.483 1.00 21.02 ? 175 MET L C 1 ATOM 4419 O O . MET B 2 175 ? 34.264 44.871 81.475 1.00 23.02 ? 175 MET L O 1 ATOM 4420 C CB . MET B 2 175 ? 33.713 41.624 81.571 1.00 18.94 ? 175 MET L CB 1 ATOM 4421 C CG . MET B 2 175 ? 34.582 40.892 80.586 1.00 18.27 ? 175 MET L CG 1 ATOM 4422 S SD . MET B 2 175 ? 33.472 40.098 79.405 1.00 20.39 ? 175 MET L SD 1 ATOM 4423 C CE . MET B 2 175 ? 33.143 38.639 80.345 1.00 20.44 ? 175 MET L CE 1 ATOM 4424 N N . SER B 2 176 ? 36.014 43.634 80.753 1.00 19.53 ? 176 SER L N 1 ATOM 4425 C CA . SER B 2 176 ? 36.575 44.664 79.920 1.00 19.98 ? 176 SER L CA 1 ATOM 4426 C C . SER B 2 176 ? 36.947 43.962 78.636 1.00 20.79 ? 176 SER L C 1 ATOM 4427 O O . SER B 2 176 ? 37.878 43.157 78.546 1.00 24.27 ? 176 SER L O 1 ATOM 4428 C CB . SER B 2 176 ? 37.792 45.258 80.587 1.00 18.41 ? 176 SER L CB 1 ATOM 4429 O OG . SER B 2 176 ? 38.200 46.536 80.106 1.00 20.45 ? 176 SER L OG 1 ATOM 4430 N N . SER B 2 177 ? 36.131 44.277 77.647 1.00 20.48 ? 177 SER L N 1 ATOM 4431 C CA . SER B 2 177 ? 36.285 43.714 76.343 1.00 18.35 ? 177 SER L CA 1 ATOM 4432 C C . SER B 2 177 ? 36.868 44.781 75.437 1.00 19.58 ? 177 SER L C 1 ATOM 4433 O O . SER B 2 177 ? 36.291 45.852 75.201 1.00 20.38 ? 177 SER L O 1 ATOM 4434 C CB . SER B 2 177 ? 34.932 43.283 75.949 1.00 16.79 ? 177 SER L CB 1 ATOM 4435 O OG . SER B 2 177 ? 35.209 42.298 74.986 1.00 15.23 ? 177 SER L OG 1 ATOM 4436 N N . THR B 2 178 ? 38.067 44.545 74.957 1.00 20.65 ? 178 THR L N 1 ATOM 4437 C CA . THR B 2 178 ? 38.727 45.536 74.150 1.00 23.52 ? 178 THR L CA 1 ATOM 4438 C C . THR B 2 178 ? 39.099 44.966 72.801 1.00 25.33 ? 178 THR L C 1 ATOM 4439 O O . THR B 2 178 ? 39.840 43.974 72.675 1.00 25.67 ? 178 THR L O 1 ATOM 4440 C CB . THR B 2 178 ? 39.984 46.017 74.828 1.00 24.46 ? 178 THR L CB 1 ATOM 4441 O OG1 . THR B 2 178 ? 39.639 46.157 76.203 1.00 26.18 ? 178 THR L OG1 1 ATOM 4442 C CG2 . THR B 2 178 ? 40.528 47.294 74.208 1.00 24.56 ? 178 THR L CG2 1 ATOM 4443 N N . LEU B 2 179 ? 38.456 45.611 71.828 1.00 25.96 ? 179 LEU L N 1 ATOM 4444 C CA . LEU B 2 179 ? 38.731 45.395 70.430 1.00 25.05 ? 179 LEU L CA 1 ATOM 4445 C C . LEU B 2 179 ? 39.816 46.432 70.094 1.00 27.30 ? 179 LEU L C 1 ATOM 4446 O O . LEU B 2 179 ? 39.666 47.633 70.357 1.00 28.06 ? 179 LEU L O 1 ATOM 4447 C CB . LEU B 2 179 ? 37.429 45.612 69.656 1.00 24.61 ? 179 LEU L CB 1 ATOM 4448 C CG . LEU B 2 179 ? 37.523 45.500 68.135 1.00 25.61 ? 179 LEU L CG 1 ATOM 4449 C CD1 . LEU B 2 179 ? 38.202 44.191 67.770 1.00 24.83 ? 179 LEU L CD1 1 ATOM 4450 C CD2 . LEU B 2 179 ? 36.139 45.556 67.514 1.00 27.29 ? 179 LEU L CD2 1 ATOM 4451 N N . THR B 2 180 ? 40.948 45.972 69.596 1.00 29.81 ? 180 THR L N 1 ATOM 4452 C CA . THR B 2 180 ? 42.010 46.853 69.181 1.00 31.21 ? 180 THR L CA 1 ATOM 4453 C C . THR B 2 180 ? 41.943 46.739 67.643 1.00 33.26 ? 180 THR L C 1 ATOM 4454 O O . THR B 2 180 ? 41.925 45.616 67.126 1.00 34.72 ? 180 THR L O 1 ATOM 4455 C CB . THR B 2 180 ? 43.301 46.302 69.815 1.00 32.60 ? 180 THR L CB 1 ATOM 4456 O OG1 . THR B 2 180 ? 43.145 46.268 71.248 1.00 34.60 ? 180 THR L OG1 1 ATOM 4457 C CG2 . THR B 2 180 ? 44.501 47.177 69.424 1.00 32.02 ? 180 THR L CG2 1 ATOM 4458 N N . LEU B 2 181 ? 41.946 47.824 66.854 1.00 32.95 ? 181 LEU L N 1 ATOM 4459 C CA . LEU B 2 181 ? 41.730 47.822 65.403 1.00 31.36 ? 181 LEU L CA 1 ATOM 4460 C C . LEU B 2 181 ? 42.670 48.805 64.709 1.00 33.01 ? 181 LEU L C 1 ATOM 4461 O O . LEU B 2 181 ? 43.426 49.551 65.344 1.00 34.54 ? 181 LEU L O 1 ATOM 4462 C CB . LEU B 2 181 ? 40.308 48.247 65.067 1.00 28.27 ? 181 LEU L CB 1 ATOM 4463 C CG . LEU B 2 181 ? 39.574 47.530 63.953 1.00 26.72 ? 181 LEU L CG 1 ATOM 4464 C CD1 . LEU B 2 181 ? 39.316 46.101 64.380 1.00 28.61 ? 181 LEU L CD1 1 ATOM 4465 C CD2 . LEU B 2 181 ? 38.228 48.169 63.693 1.00 24.03 ? 181 LEU L CD2 1 ATOM 4466 N N . THR B 2 182 ? 42.648 48.874 63.386 1.00 34.18 ? 182 THR L N 1 ATOM 4467 C CA . THR B 2 182 ? 43.498 49.823 62.681 1.00 34.29 ? 182 THR L CA 1 ATOM 4468 C C . THR B 2 182 ? 42.659 51.043 62.305 1.00 33.45 ? 182 THR L C 1 ATOM 4469 O O . THR B 2 182 ? 41.475 50.878 61.982 1.00 32.00 ? 182 THR L O 1 ATOM 4470 C CB . THR B 2 182 ? 44.113 49.163 61.402 1.00 35.73 ? 182 THR L CB 1 ATOM 4471 O OG1 . THR B 2 182 ? 43.484 47.892 61.195 1.00 38.71 ? 182 THR L OG1 1 ATOM 4472 C CG2 . THR B 2 182 ? 45.623 49.037 61.530 1.00 34.01 ? 182 THR L CG2 1 ATOM 4473 N N . LYS B 2 183 ? 43.282 52.238 62.290 1.00 32.51 ? 183 LYS L N 1 ATOM 4474 C CA . LYS B 2 183 ? 42.632 53.492 61.944 1.00 32.74 ? 183 LYS L CA 1 ATOM 4475 C C . LYS B 2 183 ? 41.797 53.299 60.681 1.00 34.01 ? 183 LYS L C 1 ATOM 4476 O O . LYS B 2 183 ? 40.573 53.419 60.673 1.00 35.55 ? 183 LYS L O 1 ATOM 4477 C CB . LYS B 2 183 ? 43.683 54.535 61.688 1.00 31.96 ? 183 LYS L CB 1 ATOM 4478 C CG . LYS B 2 183 ? 43.290 55.934 62.096 1.00 33.78 ? 183 LYS L CG 1 ATOM 4479 C CD . LYS B 2 183 ? 44.154 56.860 61.231 1.00 35.09 ? 183 LYS L CD 1 ATOM 4480 C CE . LYS B 2 183 ? 44.207 58.340 61.643 1.00 33.99 ? 183 LYS L CE 1 ATOM 4481 N NZ . LYS B 2 183 ? 42.890 58.908 61.856 1.00 36.24 ? 183 LYS L NZ 1 ATOM 4482 N N . ASP B 2 184 ? 42.509 52.774 59.682 1.00 35.42 ? 184 ASP L N 1 ATOM 4483 C CA . ASP B 2 184 ? 41.998 52.523 58.345 1.00 37.56 ? 184 ASP L CA 1 ATOM 4484 C C . ASP B 2 184 ? 40.906 51.478 58.400 1.00 37.03 ? 184 ASP L C 1 ATOM 4485 O O . ASP B 2 184 ? 39.993 51.501 57.587 1.00 39.94 ? 184 ASP L O 1 ATOM 4486 C CB . ASP B 2 184 ? 43.108 52.005 57.421 1.00 40.13 ? 184 ASP L CB 1 ATOM 4487 C CG . ASP B 2 184 ? 44.458 52.749 57.369 1.00 44.19 ? 184 ASP L CG 1 ATOM 4488 O OD1 . ASP B 2 184 ? 45.021 53.145 58.410 1.00 47.53 ? 184 ASP L OD1 1 ATOM 4489 O OD2 . ASP B 2 184 ? 44.968 52.892 56.253 1.00 45.26 ? 184 ASP L OD2 1 ATOM 4490 N N . GLU B 2 185 ? 40.984 50.533 59.333 1.00 35.37 ? 185 GLU L N 1 ATOM 4491 C CA . GLU B 2 185 ? 39.933 49.551 59.458 1.00 33.41 ? 185 GLU L CA 1 ATOM 4492 C C . GLU B 2 185 ? 38.716 50.096 60.172 1.00 32.18 ? 185 GLU L C 1 ATOM 4493 O O . GLU B 2 185 ? 37.576 49.742 59.837 1.00 31.62 ? 185 GLU L O 1 ATOM 4494 C CB . GLU B 2 185 ? 40.420 48.353 60.203 1.00 33.36 ? 185 GLU L CB 1 ATOM 4495 C CG . GLU B 2 185 ? 39.402 47.234 60.060 1.00 33.51 ? 185 GLU L CG 1 ATOM 4496 C CD . GLU B 2 185 ? 39.796 45.856 60.592 1.00 34.43 ? 185 GLU L CD 1 ATOM 4497 O OE1 . GLU B 2 185 ? 40.928 45.639 61.060 1.00 36.49 ? 185 GLU L OE1 1 ATOM 4498 O OE2 . GLU B 2 185 ? 38.930 44.976 60.531 1.00 32.92 ? 185 GLU L OE2 1 ATOM 4499 N N . TYR B 2 186 ? 38.964 51.005 61.115 1.00 31.30 ? 186 TYR L N 1 ATOM 4500 C CA . TYR B 2 186 ? 37.897 51.606 61.874 1.00 32.51 ? 186 TYR L CA 1 ATOM 4501 C C . TYR B 2 186 ? 37.047 52.387 60.863 1.00 32.19 ? 186 TYR L C 1 ATOM 4502 O O . TYR B 2 186 ? 35.845 52.139 60.696 1.00 30.65 ? 186 TYR L O 1 ATOM 4503 C CB . TYR B 2 186 ? 38.545 52.491 62.957 1.00 34.55 ? 186 TYR L CB 1 ATOM 4504 C CG . TYR B 2 186 ? 37.595 53.288 63.855 1.00 35.52 ? 186 TYR L CG 1 ATOM 4505 C CD1 . TYR B 2 186 ? 36.440 52.745 64.386 1.00 34.80 ? 186 TYR L CD1 1 ATOM 4506 C CD2 . TYR B 2 186 ? 37.897 54.614 64.108 1.00 35.93 ? 186 TYR L CD2 1 ATOM 4507 C CE1 . TYR B 2 186 ? 35.593 53.528 65.156 1.00 34.50 ? 186 TYR L CE1 1 ATOM 4508 C CE2 . TYR B 2 186 ? 37.058 55.406 64.881 1.00 35.60 ? 186 TYR L CE2 1 ATOM 4509 C CZ . TYR B 2 186 ? 35.901 54.862 65.403 1.00 35.14 ? 186 TYR L CZ 1 ATOM 4510 O OH . TYR B 2 186 ? 35.039 55.689 66.118 1.00 36.38 ? 186 TYR L OH 1 ATOM 4511 N N . GLU B 2 187 ? 37.747 53.223 60.079 1.00 32.28 ? 187 GLU L N 1 ATOM 4512 C CA . GLU B 2 187 ? 37.162 54.074 59.036 1.00 32.03 ? 187 GLU L CA 1 ATOM 4513 C C . GLU B 2 187 ? 36.567 53.333 57.819 1.00 31.19 ? 187 GLU L C 1 ATOM 4514 O O . GLU B 2 187 ? 35.883 53.931 56.973 1.00 31.40 ? 187 GLU L O 1 ATOM 4515 C CB . GLU B 2 187 ? 38.252 55.083 58.588 1.00 32.66 ? 187 GLU L CB 1 ATOM 4516 C CG . GLU B 2 187 ? 38.667 56.023 59.760 1.00 34.70 ? 187 GLU L CG 1 ATOM 4517 C CD . GLU B 2 187 ? 39.896 56.930 59.591 1.00 36.00 ? 187 GLU L CD 1 ATOM 4518 O OE1 . GLU B 2 187 ? 40.485 56.935 58.505 1.00 37.20 ? 187 GLU L OE1 1 ATOM 4519 O OE2 . GLU B 2 187 ? 40.267 57.644 60.536 1.00 36.48 ? 187 GLU L OE2 1 ATOM 4520 N N . ARG B 2 188 ? 36.806 52.023 57.680 1.00 30.58 ? 188 ARG L N 1 ATOM 4521 C CA . ARG B 2 188 ? 36.189 51.236 56.622 1.00 29.65 ? 188 ARG L CA 1 ATOM 4522 C C . ARG B 2 188 ? 34.772 50.885 57.066 1.00 30.66 ? 188 ARG L C 1 ATOM 4523 O O . ARG B 2 188 ? 33.929 50.479 56.255 1.00 32.25 ? 188 ARG L O 1 ATOM 4524 C CB . ARG B 2 188 ? 36.968 49.949 56.376 1.00 28.21 ? 188 ARG L CB 1 ATOM 4525 C CG . ARG B 2 188 ? 37.874 50.030 55.166 1.00 26.62 ? 188 ARG L CG 1 ATOM 4526 C CD . ARG B 2 188 ? 38.424 48.660 54.814 1.00 24.81 ? 188 ARG L CD 1 ATOM 4527 N NE . ARG B 2 188 ? 39.316 48.153 55.844 1.00 23.92 ? 188 ARG L NE 1 ATOM 4528 C CZ . ARG B 2 188 ? 40.619 48.482 55.894 1.00 23.07 ? 188 ARG L CZ 1 ATOM 4529 N NH1 . ARG B 2 188 ? 41.154 49.406 55.091 1.00 22.69 ? 188 ARG L NH1 1 ATOM 4530 N NH2 . ARG B 2 188 ? 41.383 47.947 56.839 1.00 23.65 ? 188 ARG L NH2 1 ATOM 4531 N N . HIS B 2 189 ? 34.537 50.957 58.379 1.00 32.12 ? 189 HIS L N 1 ATOM 4532 C CA . HIS B 2 189 ? 33.242 50.687 58.951 1.00 34.33 ? 189 HIS L CA 1 ATOM 4533 C C . HIS B 2 189 ? 32.583 51.812 59.723 1.00 35.01 ? 189 HIS L C 1 ATOM 4534 O O . HIS B 2 189 ? 33.029 52.965 59.717 1.00 34.85 ? 189 HIS L O 1 ATOM 4535 C CB . HIS B 2 189 ? 33.428 49.499 59.805 1.00 36.73 ? 189 HIS L CB 1 ATOM 4536 C CG . HIS B 2 189 ? 33.448 48.282 58.903 1.00 38.64 ? 189 HIS L CG 1 ATOM 4537 N ND1 . HIS B 2 189 ? 32.402 47.724 58.293 1.00 40.61 ? 189 HIS L ND1 1 ATOM 4538 C CD2 . HIS B 2 189 ? 34.586 47.579 58.574 1.00 37.23 ? 189 HIS L CD2 1 ATOM 4539 C CE1 . HIS B 2 189 ? 32.855 46.697 57.621 1.00 41.18 ? 189 HIS L CE1 1 ATOM 4540 N NE2 . HIS B 2 189 ? 34.162 46.618 57.796 1.00 38.52 ? 189 HIS L NE2 1 ATOM 4541 N N . ASN B 2 190 ? 31.421 51.530 60.321 1.00 36.64 ? 190 ASN L N 1 ATOM 4542 C CA . ASN B 2 190 ? 30.754 52.502 61.179 1.00 40.22 ? 190 ASN L CA 1 ATOM 4543 C C . ASN B 2 190 ? 29.967 51.858 62.300 1.00 39.66 ? 190 ASN L C 1 ATOM 4544 O O . ASN B 2 190 ? 30.185 52.304 63.423 1.00 40.83 ? 190 ASN L O 1 ATOM 4545 C CB . ASN B 2 190 ? 29.822 53.394 60.384 1.00 44.54 ? 190 ASN L CB 1 ATOM 4546 C CG . ASN B 2 190 ? 29.138 52.606 59.295 1.00 48.36 ? 190 ASN L CG 1 ATOM 4547 O OD1 . ASN B 2 190 ? 28.731 51.454 59.509 1.00 54.18 ? 190 ASN L OD1 1 ATOM 4548 N ND2 . ASN B 2 190 ? 29.083 53.203 58.100 1.00 47.21 ? 190 ASN L ND2 1 ATOM 4549 N N . SER B 2 191 ? 29.076 50.874 62.174 1.00 39.17 ? 191 SER L N 1 ATOM 4550 C CA . SER B 2 191 ? 28.460 50.287 63.370 1.00 38.94 ? 191 SER L CA 1 ATOM 4551 C C . SER B 2 191 ? 29.364 49.323 64.147 1.00 38.28 ? 191 SER L C 1 ATOM 4552 O O . SER B 2 191 ? 29.967 48.372 63.627 1.00 39.41 ? 191 SER L O 1 ATOM 4553 C CB . SER B 2 191 ? 27.179 49.569 62.984 1.00 39.90 ? 191 SER L CB 1 ATOM 4554 O OG . SER B 2 191 ? 27.249 49.008 61.671 1.00 41.65 ? 191 SER L OG 1 ATOM 4555 N N . TYR B 2 192 ? 29.489 49.579 65.433 1.00 36.77 ? 192 TYR L N 1 ATOM 4556 C CA . TYR B 2 192 ? 30.366 48.810 66.281 1.00 33.38 ? 192 TYR L CA 1 ATOM 4557 C C . TYR B 2 192 ? 29.442 48.424 67.379 1.00 33.99 ? 192 TYR L C 1 ATOM 4558 O O . TYR B 2 192 ? 28.663 49.272 67.835 1.00 34.33 ? 192 TYR L O 1 ATOM 4559 C CB . TYR B 2 192 ? 31.510 49.679 66.836 1.00 30.93 ? 192 TYR L CB 1 ATOM 4560 C CG . TYR B 2 192 ? 32.561 49.928 65.768 1.00 30.32 ? 192 TYR L CG 1 ATOM 4561 C CD1 . TYR B 2 192 ? 33.328 48.851 65.344 1.00 29.26 ? 192 TYR L CD1 1 ATOM 4562 C CD2 . TYR B 2 192 ? 32.652 51.160 65.165 1.00 30.31 ? 192 TYR L CD2 1 ATOM 4563 C CE1 . TYR B 2 192 ? 34.193 48.996 64.294 1.00 27.92 ? 192 TYR L CE1 1 ATOM 4564 C CE2 . TYR B 2 192 ? 33.512 51.290 64.110 1.00 30.20 ? 192 TYR L CE2 1 ATOM 4565 C CZ . TYR B 2 192 ? 34.264 50.217 63.675 1.00 28.65 ? 192 TYR L CZ 1 ATOM 4566 O OH . TYR B 2 192 ? 35.061 50.347 62.557 1.00 25.50 ? 192 TYR L OH 1 ATOM 4567 N N . THR B 2 193 ? 29.512 47.160 67.755 1.00 34.51 ? 193 THR L N 1 ATOM 4568 C CA . THR B 2 193 ? 28.649 46.700 68.806 1.00 36.41 ? 193 THR L CA 1 ATOM 4569 C C . THR B 2 193 ? 29.349 45.765 69.769 1.00 37.02 ? 193 THR L C 1 ATOM 4570 O O . THR B 2 193 ? 30.253 45.001 69.421 1.00 39.32 ? 193 THR L O 1 ATOM 4571 C CB . THR B 2 193 ? 27.456 46.025 68.146 1.00 37.21 ? 193 THR L CB 1 ATOM 4572 O OG1 . THR B 2 193 ? 26.897 47.013 67.275 1.00 39.67 ? 193 THR L OG1 1 ATOM 4573 C CG2 . THR B 2 193 ? 26.422 45.495 69.139 1.00 37.38 ? 193 THR L CG2 1 ATOM 4574 N N . CYS B 2 194 ? 28.912 45.915 71.004 1.00 36.85 ? 194 CYS L N 1 ATOM 4575 C CA . CYS B 2 194 ? 29.293 45.089 72.115 1.00 35.43 ? 194 CYS L CA 1 ATOM 4576 C C . CYS B 2 194 ? 27.939 44.483 72.416 1.00 35.99 ? 194 CYS L C 1 ATOM 4577 O O . CYS B 2 194 ? 27.032 45.221 72.813 1.00 36.93 ? 194 CYS L O 1 ATOM 4578 C CB . CYS B 2 194 ? 29.772 45.972 73.252 1.00 33.73 ? 194 CYS L CB 1 ATOM 4579 S SG . CYS B 2 194 ? 30.180 45.092 74.783 1.00 31.99 ? 194 CYS L SG 1 ATOM 4580 N N . GLU B 2 195 ? 27.719 43.204 72.152 1.00 37.08 ? 195 GLU L N 1 ATOM 4581 C CA . GLU B 2 195 ? 26.451 42.555 72.448 1.00 38.66 ? 195 GLU L CA 1 ATOM 4582 C C . GLU B 2 195 ? 26.756 41.529 73.529 1.00 36.76 ? 195 GLU L C 1 ATOM 4583 O O . GLU B 2 195 ? 27.678 40.730 73.337 1.00 36.39 ? 195 GLU L O 1 ATOM 4584 C CB . GLU B 2 195 ? 25.923 41.886 71.180 1.00 42.65 ? 195 GLU L CB 1 ATOM 4585 C CG . GLU B 2 195 ? 24.669 41.005 71.382 1.00 47.48 ? 195 GLU L CG 1 ATOM 4586 C CD . GLU B 2 195 ? 24.839 39.487 71.194 1.00 50.22 ? 195 GLU L CD 1 ATOM 4587 O OE1 . GLU B 2 195 ? 25.480 38.818 72.021 1.00 51.96 ? 195 GLU L OE1 1 ATOM 4588 O OE2 . GLU B 2 195 ? 24.303 38.975 70.211 1.00 50.70 ? 195 GLU L OE2 1 ATOM 4589 N N . ALA B 2 196 ? 26.034 41.483 74.649 1.00 34.88 ? 196 ALA L N 1 ATOM 4590 C CA . ALA B 2 196 ? 26.348 40.601 75.764 1.00 33.76 ? 196 ALA L CA 1 ATOM 4591 C C . ALA B 2 196 ? 25.178 39.734 76.165 1.00 33.95 ? 196 ALA L C 1 ATOM 4592 O O . ALA B 2 196 ? 24.012 40.149 76.236 1.00 34.65 ? 196 ALA L O 1 ATOM 4593 C CB . ALA B 2 196 ? 26.753 41.394 77.017 1.00 33.22 ? 196 ALA L CB 1 ATOM 4594 N N . THR B 2 197 ? 25.483 38.510 76.503 1.00 33.91 ? 197 THR L N 1 ATOM 4595 C CA . THR B 2 197 ? 24.448 37.596 76.891 1.00 34.34 ? 197 THR L CA 1 ATOM 4596 C C . THR B 2 197 ? 24.724 37.087 78.297 1.00 33.86 ? 197 THR L C 1 ATOM 4597 O O . THR B 2 197 ? 25.662 36.318 78.551 1.00 33.66 ? 197 THR L O 1 ATOM 4598 C CB . THR B 2 197 ? 24.423 36.451 75.909 1.00 35.61 ? 197 THR L CB 1 ATOM 4599 O OG1 . THR B 2 197 ? 24.950 36.911 74.655 1.00 36.06 ? 197 THR L OG1 1 ATOM 4600 C CG2 . THR B 2 197 ? 23.010 35.909 75.807 1.00 36.35 ? 197 THR L CG2 1 ATOM 4601 N N . HIS B 2 198 ? 23.906 37.544 79.238 1.00 35.04 ? 198 HIS L N 1 ATOM 4602 C CA . HIS B 2 198 ? 24.032 37.119 80.620 1.00 35.99 ? 198 HIS L CA 1 ATOM 4603 C C . HIS B 2 198 ? 22.659 36.578 81.084 1.00 36.51 ? 198 HIS L C 1 ATOM 4604 O O . HIS B 2 198 ? 21.617 36.952 80.521 1.00 35.79 ? 198 HIS L O 1 ATOM 4605 C CB . HIS B 2 198 ? 24.504 38.338 81.411 1.00 35.41 ? 198 HIS L CB 1 ATOM 4606 C CG . HIS B 2 198 ? 24.691 38.006 82.873 1.00 35.09 ? 198 HIS L CG 1 ATOM 4607 N ND1 . HIS B 2 198 ? 23.723 38.120 83.763 1.00 35.83 ? 198 HIS L ND1 1 ATOM 4608 C CD2 . HIS B 2 198 ? 25.813 37.516 83.494 1.00 34.60 ? 198 HIS L CD2 1 ATOM 4609 C CE1 . HIS B 2 198 ? 24.197 37.720 84.909 1.00 35.71 ? 198 HIS L CE1 1 ATOM 4610 N NE2 . HIS B 2 198 ? 25.447 37.362 84.732 1.00 34.47 ? 198 HIS L NE2 1 ATOM 4611 N N . LYS B 2 199 ? 22.641 35.690 82.092 1.00 37.79 ? 199 LYS L N 1 ATOM 4612 C CA . LYS B 2 199 ? 21.444 35.097 82.719 1.00 38.79 ? 199 LYS L CA 1 ATOM 4613 C C . LYS B 2 199 ? 20.248 36.012 83.006 1.00 38.47 ? 199 LYS L C 1 ATOM 4614 O O . LYS B 2 199 ? 19.088 35.594 82.981 1.00 39.75 ? 199 LYS L O 1 ATOM 4615 C CB . LYS B 2 199 ? 21.864 34.414 84.052 1.00 39.49 ? 199 LYS L CB 1 ATOM 4616 C CG . LYS B 2 199 ? 20.714 33.908 84.926 1.00 40.17 ? 199 LYS L CG 1 ATOM 4617 C CD . LYS B 2 199 ? 21.155 32.983 86.026 1.00 41.70 ? 199 LYS L CD 1 ATOM 4618 C CE . LYS B 2 199 ? 19.889 32.442 86.683 1.00 44.18 ? 199 LYS L CE 1 ATOM 4619 N NZ . LYS B 2 199 ? 20.232 31.661 87.850 1.00 45.34 ? 199 LYS L NZ 1 ATOM 4620 N N . THR B 2 200 ? 20.505 37.277 83.300 1.00 38.78 ? 200 THR L N 1 ATOM 4621 C CA . THR B 2 200 ? 19.444 38.199 83.640 1.00 39.61 ? 200 THR L CA 1 ATOM 4622 C C . THR B 2 200 ? 18.455 38.587 82.538 1.00 40.53 ? 200 THR L C 1 ATOM 4623 O O . THR B 2 200 ? 17.538 39.385 82.801 1.00 43.24 ? 200 THR L O 1 ATOM 4624 C CB . THR B 2 200 ? 20.134 39.438 84.257 1.00 38.91 ? 200 THR L CB 1 ATOM 4625 O OG1 . THR B 2 200 ? 21.383 39.676 83.599 1.00 38.94 ? 200 THR L OG1 1 ATOM 4626 C CG2 . THR B 2 200 ? 20.381 39.213 85.734 1.00 39.11 ? 200 THR L CG2 1 ATOM 4627 N N . SER B 2 201 ? 18.624 38.011 81.333 1.00 39.05 ? 201 SER L N 1 ATOM 4628 C CA . SER B 2 201 ? 17.791 38.326 80.195 1.00 38.80 ? 201 SER L CA 1 ATOM 4629 C C . SER B 2 201 ? 17.520 37.067 79.383 1.00 39.95 ? 201 SER L C 1 ATOM 4630 O O . SER B 2 201 ? 17.659 35.931 79.838 1.00 42.04 ? 201 SER L O 1 ATOM 4631 C CB . SER B 2 201 ? 18.490 39.386 79.334 1.00 37.22 ? 201 SER L CB 1 ATOM 4632 O OG . SER B 2 201 ? 17.491 40.015 78.524 1.00 38.50 ? 201 SER L OG 1 ATOM 4633 N N . THR B 2 202 ? 17.014 37.357 78.188 1.00 40.95 ? 202 THR L N 1 ATOM 4634 C CA . THR B 2 202 ? 16.631 36.454 77.116 1.00 41.75 ? 202 THR L CA 1 ATOM 4635 C C . THR B 2 202 ? 17.240 37.204 75.917 1.00 42.26 ? 202 THR L C 1 ATOM 4636 O O . THR B 2 202 ? 18.146 36.760 75.202 1.00 44.32 ? 202 THR L O 1 ATOM 4637 C CB . THR B 2 202 ? 15.005 36.325 77.100 1.00 42.59 ? 202 THR L CB 1 ATOM 4638 O OG1 . THR B 2 202 ? 14.569 36.469 75.751 1.00 44.80 ? 202 THR L OG1 1 ATOM 4639 C CG2 . THR B 2 202 ? 14.235 37.391 77.926 1.00 42.92 ? 202 THR L CG2 1 ATOM 4640 N N . SER B 2 203 ? 16.738 38.423 75.762 1.00 41.17 ? 203 SER L N 1 ATOM 4641 C CA . SER B 2 203 ? 17.085 39.352 74.714 1.00 40.58 ? 203 SER L CA 1 ATOM 4642 C C . SER B 2 203 ? 18.385 39.992 75.114 1.00 39.48 ? 203 SER L C 1 ATOM 4643 O O . SER B 2 203 ? 18.409 40.648 76.159 1.00 41.05 ? 203 SER L O 1 ATOM 4644 C CB . SER B 2 203 ? 15.987 40.401 74.604 1.00 41.34 ? 203 SER L CB 1 ATOM 4645 O OG . SER B 2 203 ? 14.853 40.054 75.423 1.00 44.49 ? 203 SER L OG 1 ATOM 4646 N N . PRO B 2 204 ? 19.460 39.779 74.354 1.00 38.13 ? 204 PRO L N 1 ATOM 4647 C CA . PRO B 2 204 ? 20.790 40.278 74.591 1.00 37.59 ? 204 PRO L CA 1 ATOM 4648 C C . PRO B 2 204 ? 20.782 41.735 74.934 1.00 36.80 ? 204 PRO L C 1 ATOM 4649 O O . PRO B 2 204 ? 20.002 42.545 74.405 1.00 38.73 ? 204 PRO L O 1 ATOM 4650 C CB . PRO B 2 204 ? 21.552 40.022 73.325 1.00 37.07 ? 204 PRO L CB 1 ATOM 4651 C CG . PRO B 2 204 ? 20.977 38.700 72.935 1.00 37.88 ? 204 PRO L CG 1 ATOM 4652 C CD . PRO B 2 204 ? 19.495 38.998 73.130 1.00 37.96 ? 204 PRO L CD 1 ATOM 4653 N N . ILE B 2 205 ? 21.727 41.970 75.833 1.00 33.86 ? 205 ILE L N 1 ATOM 4654 C CA . ILE B 2 205 ? 22.005 43.318 76.274 1.00 30.95 ? 205 ILE L CA 1 ATOM 4655 C C . ILE B 2 205 ? 22.820 43.825 75.067 1.00 29.80 ? 205 ILE L C 1 ATOM 4656 O O . ILE B 2 205 ? 23.759 43.132 74.651 1.00 29.89 ? 205 ILE L O 1 ATOM 4657 C CB . ILE B 2 205 ? 22.847 43.272 77.575 1.00 30.63 ? 205 ILE L CB 1 ATOM 4658 C CG1 . ILE B 2 205 ? 22.557 42.064 78.497 1.00 28.91 ? 205 ILE L CG1 1 ATOM 4659 C CG2 . ILE B 2 205 ? 22.535 44.610 78.273 1.00 32.01 ? 205 ILE L CG2 1 ATOM 4660 C CD1 . ILE B 2 205 ? 21.214 42.078 79.270 1.00 30.51 ? 205 ILE L CD1 1 ATOM 4661 N N . VAL B 2 206 ? 22.528 44.931 74.380 1.00 29.61 ? 206 VAL L N 1 ATOM 4662 C CA . VAL B 2 206 ? 23.314 45.267 73.198 1.00 29.48 ? 206 VAL L CA 1 ATOM 4663 C C . VAL B 2 206 ? 23.705 46.751 73.185 1.00 29.86 ? 206 VAL L C 1 ATOM 4664 O O . VAL B 2 206 ? 22.801 47.595 73.166 1.00 32.35 ? 206 VAL L O 1 ATOM 4665 C CB . VAL B 2 206 ? 22.488 44.877 71.917 1.00 29.13 ? 206 VAL L CB 1 ATOM 4666 C CG1 . VAL B 2 206 ? 23.381 45.019 70.693 1.00 29.84 ? 206 VAL L CG1 1 ATOM 4667 C CG2 . VAL B 2 206 ? 22.035 43.415 71.936 1.00 29.17 ? 206 VAL L CG2 1 ATOM 4668 N N . LYS B 2 207 ? 24.997 47.138 73.246 1.00 28.45 ? 207 LYS L N 1 ATOM 4669 C CA . LYS B 2 207 ? 25.403 48.549 73.175 1.00 26.58 ? 207 LYS L CA 1 ATOM 4670 C C . LYS B 2 207 ? 26.186 48.814 71.882 1.00 24.79 ? 207 LYS L C 1 ATOM 4671 O O . LYS B 2 207 ? 27.047 48.019 71.502 1.00 23.33 ? 207 LYS L O 1 ATOM 4672 C CB . LYS B 2 207 ? 26.258 48.900 74.401 1.00 26.96 ? 207 LYS L CB 1 ATOM 4673 C CG . LYS B 2 207 ? 25.736 50.084 75.213 1.00 28.02 ? 207 LYS L CG 1 ATOM 4674 C CD . LYS B 2 207 ? 24.411 49.771 75.940 1.00 29.32 ? 207 LYS L CD 1 ATOM 4675 C CE . LYS B 2 207 ? 24.063 50.779 77.101 1.00 30.94 ? 207 LYS L CE 1 ATOM 4676 N NZ . LYS B 2 207 ? 23.475 52.076 76.739 1.00 32.51 ? 207 LYS L NZ 1 ATOM 4677 N N . SER B 2 208 ? 25.935 49.932 71.204 1.00 23.99 ? 208 SER L N 1 ATOM 4678 C CA . SER B 2 208 ? 26.491 50.219 69.883 1.00 24.30 ? 208 SER L CA 1 ATOM 4679 C C . SER B 2 208 ? 26.787 51.693 69.658 1.00 27.48 ? 208 SER L C 1 ATOM 4680 O O . SER B 2 208 ? 26.055 52.526 70.207 1.00 27.49 ? 208 SER L O 1 ATOM 4681 C CB . SER B 2 208 ? 25.507 49.779 68.815 1.00 21.98 ? 208 SER L CB 1 ATOM 4682 O OG . SER B 2 208 ? 25.082 48.427 68.995 1.00 22.66 ? 208 SER L OG 1 ATOM 4683 N N . PHE B 2 209 ? 27.807 52.084 68.877 1.00 32.74 ? 209 PHE L N 1 ATOM 4684 C CA . PHE B 2 209 ? 28.122 53.499 68.720 1.00 35.52 ? 209 PHE L CA 1 ATOM 4685 C C . PHE B 2 209 ? 28.521 53.925 67.322 1.00 37.49 ? 209 PHE L C 1 ATOM 4686 O O . PHE B 2 209 ? 28.859 53.108 66.468 1.00 36.76 ? 209 PHE L O 1 ATOM 4687 C CB . PHE B 2 209 ? 29.293 53.916 69.666 1.00 36.77 ? 209 PHE L CB 1 ATOM 4688 C CG . PHE B 2 209 ? 30.706 53.774 69.081 1.00 36.66 ? 209 PHE L CG 1 ATOM 4689 C CD1 . PHE B 2 209 ? 31.351 52.548 69.082 1.00 38.01 ? 209 PHE L CD1 1 ATOM 4690 C CD2 . PHE B 2 209 ? 31.315 54.880 68.493 1.00 36.76 ? 209 PHE L CD2 1 ATOM 4691 C CE1 . PHE B 2 209 ? 32.591 52.447 68.488 1.00 39.60 ? 209 PHE L CE1 1 ATOM 4692 C CE2 . PHE B 2 209 ? 32.550 54.765 67.898 1.00 37.37 ? 209 PHE L CE2 1 ATOM 4693 C CZ . PHE B 2 209 ? 33.187 53.545 67.897 1.00 38.63 ? 209 PHE L CZ 1 ATOM 4694 N N . ASN B 2 210 ? 28.542 55.251 67.216 1.00 40.76 ? 210 ASN L N 1 ATOM 4695 C CA . ASN B 2 210 ? 29.280 56.042 66.238 1.00 42.99 ? 210 ASN L CA 1 ATOM 4696 C C . ASN B 2 210 ? 28.958 57.521 66.485 1.00 43.28 ? 210 ASN L C 1 ATOM 4697 O O . ASN B 2 210 ? 27.853 57.913 66.903 1.00 44.76 ? 210 ASN L O 1 ATOM 4698 C CB . ASN B 2 210 ? 28.991 55.710 64.782 1.00 44.10 ? 210 ASN L CB 1 ATOM 4699 C CG . ASN B 2 210 ? 30.365 55.979 64.149 1.00 45.93 ? 210 ASN L CG 1 ATOM 4700 O OD1 . ASN B 2 210 ? 30.759 57.127 63.917 1.00 47.78 ? 210 ASN L OD1 1 ATOM 4701 N ND2 . ASN B 2 210 ? 31.221 54.984 63.930 1.00 45.23 ? 210 ASN L ND2 1 ATOM 4702 N N . ARG B 2 211 ? 30.002 58.331 66.320 1.00 42.79 ? 211 ARG L N 1 ATOM 4703 C CA . ARG B 2 211 ? 30.033 59.709 66.774 1.00 42.57 ? 211 ARG L CA 1 ATOM 4704 C C . ARG B 2 211 ? 28.952 60.657 66.297 1.00 43.15 ? 211 ARG L C 1 ATOM 4705 O O . ARG B 2 211 ? 28.812 60.968 65.116 1.00 43.40 ? 211 ARG L O 1 ATOM 4706 C CB . ARG B 2 211 ? 31.395 60.300 66.427 1.00 41.96 ? 211 ARG L CB 1 ATOM 4707 C CG . ARG B 2 211 ? 32.541 59.694 67.222 1.00 41.63 ? 211 ARG L CG 1 ATOM 4708 C CD . ARG B 2 211 ? 33.886 60.059 66.608 1.00 41.09 ? 211 ARG L CD 1 ATOM 4709 N NE . ARG B 2 211 ? 34.152 61.491 66.614 1.00 40.62 ? 211 ARG L NE 1 ATOM 4710 C CZ . ARG B 2 211 ? 34.869 62.083 65.650 1.00 40.22 ? 211 ARG L CZ 1 ATOM 4711 N NH1 . ARG B 2 211 ? 35.291 61.411 64.579 1.00 39.89 ? 211 ARG L NH1 1 ATOM 4712 N NH2 . ARG B 2 211 ? 35.125 63.387 65.721 1.00 40.30 ? 211 ARG L NH2 1 ATOM 4713 N N . ASN B 2 212 ? 28.203 61.131 67.281 1.00 44.06 ? 212 ASN L N 1 ATOM 4714 C CA . ASN B 2 212 ? 27.136 62.092 67.084 1.00 44.98 ? 212 ASN L CA 1 ATOM 4715 C C . ASN B 2 212 ? 27.111 62.917 68.363 1.00 45.40 ? 212 ASN L C 1 ATOM 4716 O O . ASN B 2 212 ? 27.544 62.418 69.408 1.00 45.35 ? 212 ASN L O 1 ATOM 4717 C CB . ASN B 2 212 ? 25.793 61.384 66.900 1.00 45.27 ? 212 ASN L CB 1 ATOM 4718 C CG . ASN B 2 212 ? 24.632 62.330 66.623 1.00 45.40 ? 212 ASN L CG 1 ATOM 4719 O OD1 . ASN B 2 212 ? 24.801 63.493 66.253 1.00 45.55 ? 212 ASN L OD1 1 ATOM 4720 N ND2 . ASN B 2 212 ? 23.398 61.873 66.762 1.00 45.34 ? 212 ASN L ND2 1 ATOM 4721 N N . GLU B 2 213 ? 26.642 64.161 68.290 1.00 45.89 ? 213 GLU L N 1 ATOM 4722 C CA . GLU B 2 213 ? 26.576 65.028 69.455 1.00 46.34 ? 213 GLU L CA 1 ATOM 4723 C C . GLU B 2 213 ? 25.373 64.657 70.300 1.00 46.17 ? 213 GLU L C 1 ATOM 4724 O O . GLU B 2 213 ? 24.481 63.926 69.845 1.00 46.73 ? 213 GLU L O 1 ATOM 4725 C CB . GLU B 2 213 ? 26.452 66.495 69.043 1.00 46.75 ? 213 GLU L CB 1 ATOM 4726 C CG . GLU B 2 213 ? 27.746 67.222 68.683 1.00 47.50 ? 213 GLU L CG 1 ATOM 4727 C CD . GLU B 2 213 ? 28.502 66.658 67.490 1.00 47.91 ? 213 GLU L CD 1 ATOM 4728 O OE1 . GLU B 2 213 ? 28.094 66.904 66.356 1.00 48.22 ? 213 GLU L OE1 1 ATOM 4729 O OE2 . GLU B 2 213 ? 29.503 65.974 67.706 1.00 48.22 ? 213 GLU L OE2 1 ATOM 4730 N N . CYS B 2 214 ? 25.338 65.207 71.507 1.00 45.80 ? 214 CYS L N 1 ATOM 4731 C CA . CYS B 2 214 ? 24.266 64.969 72.447 1.00 45.38 ? 214 CYS L CA 1 ATOM 4732 C C . CYS B 2 214 ? 24.027 66.279 73.196 1.00 45.65 ? 214 CYS L C 1 ATOM 4733 O O . CYS B 2 214 ? 22.883 66.539 73.560 1.00 45.78 ? 214 CYS L O 1 ATOM 4734 C CB . CYS B 2 214 ? 24.671 63.886 73.436 1.00 44.77 ? 214 CYS L CB 1 ATOM 4735 S SG . CYS B 2 214 ? 25.383 62.384 72.715 1.00 43.84 ? 214 CYS L SG 1 ATOM 4736 O OXT . CYS B 2 214 ? 24.977 67.037 73.400 1.00 45.75 ? 214 CYS L OXT 1 ATOM 4737 N N . GLN C 3 1 ? 53.544 46.185 115.044 1.00 35.69 ? 1 GLN H N 1 ATOM 4738 C CA . GLN C 3 1 ? 53.468 44.872 115.643 1.00 35.67 ? 1 GLN H CA 1 ATOM 4739 C C . GLN C 3 1 ? 54.427 44.090 114.764 1.00 33.24 ? 1 GLN H C 1 ATOM 4740 O O . GLN C 3 1 ? 55.503 44.678 114.635 1.00 35.04 ? 1 GLN H O 1 ATOM 4741 C CB . GLN C 3 1 ? 52.041 44.311 115.566 1.00 39.61 ? 1 GLN H CB 1 ATOM 4742 C CG . GLN C 3 1 ? 51.748 43.326 116.723 1.00 43.56 ? 1 GLN H CG 1 ATOM 4743 C CD . GLN C 3 1 ? 51.752 43.970 118.120 1.00 46.24 ? 1 GLN H CD 1 ATOM 4744 O OE1 . GLN C 3 1 ? 52.518 44.897 118.394 1.00 47.66 ? 1 GLN H OE1 1 ATOM 4745 N NE2 . GLN C 3 1 ? 50.913 43.536 119.053 1.00 46.84 ? 1 GLN H NE2 1 ATOM 4746 N N . ILE C 3 2 ? 54.182 42.945 114.093 1.00 27.75 ? 2 ILE H N 1 ATOM 4747 C CA . ILE C 3 2 ? 55.261 42.296 113.345 1.00 22.06 ? 2 ILE H CA 1 ATOM 4748 C C . ILE C 3 2 ? 54.988 42.661 111.916 1.00 23.34 ? 2 ILE H C 1 ATOM 4749 O O . ILE C 3 2 ? 53.835 42.550 111.490 1.00 26.12 ? 2 ILE H O 1 ATOM 4750 C CB . ILE C 3 2 ? 55.225 40.771 113.571 1.00 16.50 ? 2 ILE H CB 1 ATOM 4751 C CG1 . ILE C 3 2 ? 55.838 40.558 114.926 1.00 12.89 ? 2 ILE H CG1 1 ATOM 4752 C CG2 . ILE C 3 2 ? 56.009 39.965 112.555 1.00 14.04 ? 2 ILE H CG2 1 ATOM 4753 C CD1 . ILE C 3 2 ? 55.543 39.172 115.486 1.00 9.33 ? 2 ILE H CD1 1 ATOM 4754 N N . GLN C 3 3 ? 56.017 43.164 111.247 1.00 22.22 ? 3 GLN H N 1 ATOM 4755 C CA . GLN C 3 3 ? 55.901 43.639 109.882 1.00 21.22 ? 3 GLN H CA 1 ATOM 4756 C C . GLN C 3 3 ? 57.098 43.085 109.087 1.00 19.39 ? 3 GLN H C 1 ATOM 4757 O O . GLN C 3 3 ? 58.254 43.076 109.556 1.00 19.77 ? 3 GLN H O 1 ATOM 4758 C CB . GLN C 3 3 ? 55.966 45.195 109.785 1.00 23.06 ? 3 GLN H CB 1 ATOM 4759 C CG . GLN C 3 3 ? 55.467 46.155 110.879 1.00 27.16 ? 3 GLN H CG 1 ATOM 4760 C CD . GLN C 3 3 ? 53.952 46.198 111.124 1.00 30.79 ? 3 GLN H CD 1 ATOM 4761 O OE1 . GLN C 3 3 ? 53.463 46.325 112.275 1.00 35.04 ? 3 GLN H OE1 1 ATOM 4762 N NE2 . GLN C 3 3 ? 53.137 46.085 110.071 1.00 30.81 ? 3 GLN H NE2 1 ATOM 4763 N N . LEU C 3 4 ? 56.897 42.608 107.861 1.00 17.29 ? 4 LEU H N 1 ATOM 4764 C CA . LEU C 3 4 ? 58.003 42.121 107.042 1.00 17.18 ? 4 LEU H CA 1 ATOM 4765 C C . LEU C 3 4 ? 57.656 42.706 105.696 1.00 17.78 ? 4 LEU H C 1 ATOM 4766 O O . LEU C 3 4 ? 56.604 42.423 105.098 1.00 19.86 ? 4 LEU H O 1 ATOM 4767 C CB . LEU C 3 4 ? 58.039 40.598 106.894 1.00 16.32 ? 4 LEU H CB 1 ATOM 4768 C CG . LEU C 3 4 ? 57.874 39.715 108.123 1.00 16.59 ? 4 LEU H CG 1 ATOM 4769 C CD1 . LEU C 3 4 ? 57.899 38.260 107.740 1.00 17.34 ? 4 LEU H CD1 1 ATOM 4770 C CD2 . LEU C 3 4 ? 58.982 39.990 109.080 1.00 17.16 ? 4 LEU H CD2 1 ATOM 4771 N N . VAL C 3 5 ? 58.529 43.614 105.301 1.00 19.90 ? 5 VAL H N 1 ATOM 4772 C CA . VAL C 3 5 ? 58.445 44.317 104.039 1.00 22.03 ? 5 VAL H CA 1 ATOM 4773 C C . VAL C 3 5 ? 59.474 43.613 103.174 1.00 21.61 ? 5 VAL H C 1 ATOM 4774 O O . VAL C 3 5 ? 60.515 43.186 103.707 1.00 24.80 ? 5 VAL H O 1 ATOM 4775 C CB . VAL C 3 5 ? 58.794 45.771 104.304 1.00 23.08 ? 5 VAL H CB 1 ATOM 4776 C CG1 . VAL C 3 5 ? 59.236 46.549 103.064 1.00 24.73 ? 5 VAL H CG1 1 ATOM 4777 C CG2 . VAL C 3 5 ? 57.524 46.371 104.870 1.00 25.14 ? 5 VAL H CG2 1 ATOM 4778 N N . GLN C 3 6 ? 59.188 43.470 101.868 1.00 20.76 ? 6 GLN H N 1 ATOM 4779 C CA . GLN C 3 6 ? 60.098 42.797 100.947 1.00 21.29 ? 6 GLN H CA 1 ATOM 4780 C C . GLN C 3 6 ? 60.519 43.763 99.870 1.00 23.40 ? 6 GLN H C 1 ATOM 4781 O O . GLN C 3 6 ? 60.035 44.905 99.836 1.00 24.70 ? 6 GLN H O 1 ATOM 4782 C CB . GLN C 3 6 ? 59.452 41.623 100.287 1.00 19.86 ? 6 GLN H CB 1 ATOM 4783 C CG . GLN C 3 6 ? 59.530 40.422 101.180 1.00 19.26 ? 6 GLN H CG 1 ATOM 4784 C CD . GLN C 3 6 ? 58.654 39.354 100.624 1.00 19.25 ? 6 GLN H CD 1 ATOM 4785 O OE1 . GLN C 3 6 ? 58.590 39.164 99.439 1.00 17.40 ? 6 GLN H OE1 1 ATOM 4786 N NE2 . GLN C 3 6 ? 57.855 38.619 101.355 1.00 22.50 ? 6 GLN H NE2 1 ATOM 4787 N N . SER C 3 7 ? 61.449 43.366 99.020 1.00 25.64 ? 7 SER H N 1 ATOM 4788 C CA . SER C 3 7 ? 61.874 44.297 98.015 1.00 28.18 ? 7 SER H CA 1 ATOM 4789 C C . SER C 3 7 ? 60.768 44.560 96.975 1.00 29.63 ? 7 SER H C 1 ATOM 4790 O O . SER C 3 7 ? 59.706 43.924 96.900 1.00 29.51 ? 7 SER H O 1 ATOM 4791 C CB . SER C 3 7 ? 63.163 43.736 97.387 1.00 27.91 ? 7 SER H CB 1 ATOM 4792 O OG . SER C 3 7 ? 63.076 42.395 96.904 1.00 32.14 ? 7 SER H OG 1 ATOM 4793 N N . GLY C 3 8 ? 61.026 45.579 96.153 1.00 31.77 ? 8 GLY H N 1 ATOM 4794 C CA . GLY C 3 8 ? 60.134 45.892 95.048 1.00 34.97 ? 8 GLY H CA 1 ATOM 4795 C C . GLY C 3 8 ? 60.330 44.824 93.974 1.00 34.99 ? 8 GLY H C 1 ATOM 4796 O O . GLY C 3 8 ? 61.409 44.208 93.955 1.00 33.41 ? 8 GLY H O 1 ATOM 4797 N N . PRO C 3 9 ? 59.331 44.570 93.115 1.00 35.45 ? 9 PRO H N 1 ATOM 4798 C CA . PRO C 3 9 ? 59.325 43.446 92.183 1.00 36.20 ? 9 PRO H CA 1 ATOM 4799 C C . PRO C 3 9 ? 60.372 43.666 91.099 1.00 37.47 ? 9 PRO H C 1 ATOM 4800 O O . PRO C 3 9 ? 60.641 44.825 90.766 1.00 43.74 ? 9 PRO H O 1 ATOM 4801 C CB . PRO C 3 9 ? 57.885 43.425 91.748 1.00 34.48 ? 9 PRO H CB 1 ATOM 4802 C CG . PRO C 3 9 ? 57.502 44.890 91.686 1.00 33.73 ? 9 PRO H CG 1 ATOM 4803 C CD . PRO C 3 9 ? 58.214 45.480 92.884 1.00 34.63 ? 9 PRO H CD 1 ATOM 4804 N N . GLU C 3 10 ? 60.999 42.615 90.566 1.00 34.47 ? 10 GLU H N 1 ATOM 4805 C CA . GLU C 3 10 ? 62.102 42.805 89.640 1.00 31.58 ? 10 GLU H CA 1 ATOM 4806 C C . GLU C 3 10 ? 61.930 42.181 88.269 1.00 28.46 ? 10 GLU H C 1 ATOM 4807 O O . GLU C 3 10 ? 61.266 41.136 88.143 1.00 30.67 ? 10 GLU H O 1 ATOM 4808 C CB . GLU C 3 10 ? 63.394 42.276 90.294 1.00 32.22 ? 10 GLU H CB 1 ATOM 4809 C CG . GLU C 3 10 ? 64.214 43.436 90.862 1.00 38.67 ? 10 GLU H CG 1 ATOM 4810 C CD . GLU C 3 10 ? 65.302 43.075 91.877 1.00 44.08 ? 10 GLU H CD 1 ATOM 4811 O OE1 . GLU C 3 10 ? 64.971 42.519 92.939 1.00 47.26 ? 10 GLU H OE1 1 ATOM 4812 O OE2 . GLU C 3 10 ? 66.473 43.370 91.612 1.00 47.33 ? 10 GLU H OE2 1 ATOM 4813 N N . LEU C 3 11 ? 62.505 42.864 87.259 1.00 24.81 ? 11 LEU H N 1 ATOM 4814 C CA . LEU C 3 11 ? 62.517 42.311 85.916 1.00 22.07 ? 11 LEU H CA 1 ATOM 4815 C C . LEU C 3 11 ? 63.928 41.823 85.647 1.00 22.38 ? 11 LEU H C 1 ATOM 4816 O O . LEU C 3 11 ? 64.858 42.633 85.755 1.00 22.07 ? 11 LEU H O 1 ATOM 4817 C CB . LEU C 3 11 ? 62.167 43.349 84.830 1.00 20.65 ? 11 LEU H CB 1 ATOM 4818 C CG . LEU C 3 11 ? 62.050 42.930 83.324 1.00 18.01 ? 11 LEU H CG 1 ATOM 4819 C CD1 . LEU C 3 11 ? 61.040 41.790 83.124 1.00 18.61 ? 11 LEU H CD1 1 ATOM 4820 C CD2 . LEU C 3 11 ? 61.625 44.155 82.507 1.00 18.15 ? 11 LEU H CD2 1 ATOM 4821 N N . LYS C 3 12 ? 64.127 40.531 85.364 1.00 23.63 ? 12 LYS H N 1 ATOM 4822 C CA . LYS C 3 12 ? 65.429 39.979 85.022 1.00 24.64 ? 12 LYS H CA 1 ATOM 4823 C C . LYS C 3 12 ? 65.128 39.073 83.848 1.00 23.59 ? 12 LYS H C 1 ATOM 4824 O O . LYS C 3 12 ? 64.084 38.429 83.776 1.00 20.56 ? 12 LYS H O 1 ATOM 4825 C CB . LYS C 3 12 ? 66.034 39.142 86.165 1.00 27.35 ? 12 LYS H CB 1 ATOM 4826 C CG . LYS C 3 12 ? 66.511 39.865 87.435 1.00 29.06 ? 12 LYS H CG 1 ATOM 4827 C CD . LYS C 3 12 ? 67.667 40.838 87.171 1.00 29.92 ? 12 LYS H CD 1 ATOM 4828 C CE . LYS C 3 12 ? 68.165 41.633 88.407 1.00 29.10 ? 12 LYS H CE 1 ATOM 4829 N NZ . LYS C 3 12 ? 67.338 42.764 88.851 1.00 35.97 ? 12 LYS H NZ 1 ATOM 4830 N N . LYS C 3 13 ? 66.051 39.109 82.897 1.00 24.40 ? 13 LYS H N 1 ATOM 4831 C CA . LYS C 3 13 ? 66.061 38.367 81.633 1.00 23.25 ? 13 LYS H CA 1 ATOM 4832 C C . LYS C 3 13 ? 66.709 37.022 81.948 1.00 24.22 ? 13 LYS H C 1 ATOM 4833 O O . LYS C 3 13 ? 67.536 36.964 82.872 1.00 24.08 ? 13 LYS H O 1 ATOM 4834 C CB . LYS C 3 13 ? 66.889 39.175 80.620 1.00 21.77 ? 13 LYS H CB 1 ATOM 4835 C CG . LYS C 3 13 ? 67.157 38.636 79.219 1.00 21.99 ? 13 LYS H CG 1 ATOM 4836 C CD . LYS C 3 13 ? 68.072 39.616 78.503 1.00 21.83 ? 13 LYS H CD 1 ATOM 4837 C CE . LYS C 3 13 ? 68.368 39.193 77.073 1.00 21.05 ? 13 LYS H CE 1 ATOM 4838 N NZ . LYS C 3 13 ? 69.236 40.179 76.458 1.00 19.04 ? 13 LYS H NZ 1 ATOM 4839 N N . PRO C 3 14 ? 66.358 35.924 81.285 1.00 26.34 ? 14 PRO H N 1 ATOM 4840 C CA . PRO C 3 14 ? 66.846 34.585 81.587 1.00 27.93 ? 14 PRO H CA 1 ATOM 4841 C C . PRO C 3 14 ? 68.335 34.434 81.746 1.00 30.07 ? 14 PRO H C 1 ATOM 4842 O O . PRO C 3 14 ? 69.069 34.781 80.822 1.00 31.13 ? 14 PRO H O 1 ATOM 4843 C CB . PRO C 3 14 ? 66.320 33.716 80.485 1.00 27.31 ? 14 PRO H CB 1 ATOM 4844 C CG . PRO C 3 14 ? 64.977 34.370 80.238 1.00 27.51 ? 14 PRO H CG 1 ATOM 4845 C CD . PRO C 3 14 ? 65.298 35.869 80.294 1.00 27.04 ? 14 PRO H CD 1 ATOM 4846 N N . GLY C 3 15 ? 68.763 33.995 82.926 1.00 32.45 ? 15 GLY H N 1 ATOM 4847 C CA . GLY C 3 15 ? 70.159 33.738 83.182 1.00 34.06 ? 15 GLY H CA 1 ATOM 4848 C C . GLY C 3 15 ? 70.735 34.542 84.327 1.00 33.80 ? 15 GLY H C 1 ATOM 4849 O O . GLY C 3 15 ? 71.697 34.119 84.991 1.00 34.02 ? 15 GLY H O 1 ATOM 4850 N N . GLU C 3 16 ? 70.150 35.690 84.644 1.00 34.24 ? 16 GLU H N 1 ATOM 4851 C CA . GLU C 3 16 ? 70.712 36.515 85.703 1.00 36.06 ? 16 GLU H CA 1 ATOM 4852 C C . GLU C 3 16 ? 70.492 35.945 87.109 1.00 35.29 ? 16 GLU H C 1 ATOM 4853 O O . GLU C 3 16 ? 69.959 34.843 87.286 1.00 34.61 ? 16 GLU H O 1 ATOM 4854 C CB . GLU C 3 16 ? 70.117 37.904 85.603 1.00 39.16 ? 16 GLU H CB 1 ATOM 4855 C CG . GLU C 3 16 ? 70.615 38.683 84.399 1.00 43.84 ? 16 GLU H CG 1 ATOM 4856 C CD . GLU C 3 16 ? 69.744 39.890 84.078 1.00 46.25 ? 16 GLU H CD 1 ATOM 4857 O OE1 . GLU C 3 16 ? 68.787 39.711 83.341 1.00 48.79 ? 16 GLU H OE1 1 ATOM 4858 O OE2 . GLU C 3 16 ? 70.007 40.995 84.557 1.00 47.84 ? 16 GLU H OE2 1 ATOM 4859 N N . THR C 3 17 ? 70.952 36.691 88.113 1.00 34.63 ? 17 THR H N 1 ATOM 4860 C CA . THR C 3 17 ? 70.876 36.315 89.507 1.00 33.47 ? 17 THR H CA 1 ATOM 4861 C C . THR C 3 17 ? 70.102 37.424 90.174 1.00 33.39 ? 17 THR H C 1 ATOM 4862 O O . THR C 3 17 ? 70.254 38.586 89.763 1.00 34.03 ? 17 THR H O 1 ATOM 4863 C CB . THR C 3 17 ? 72.290 36.225 90.005 1.00 33.62 ? 17 THR H CB 1 ATOM 4864 O OG1 . THR C 3 17 ? 72.841 35.114 89.308 1.00 35.37 ? 17 THR H OG1 1 ATOM 4865 C CG2 . THR C 3 17 ? 72.413 36.089 91.492 1.00 32.12 ? 17 THR H CG2 1 ATOM 4866 N N . VAL C 3 18 ? 69.324 37.098 91.207 1.00 31.94 ? 18 VAL H N 1 ATOM 4867 C CA . VAL C 3 18 ? 68.456 38.080 91.850 1.00 29.96 ? 18 VAL H CA 1 ATOM 4868 C C . VAL C 3 18 ? 68.380 37.808 93.343 1.00 28.78 ? 18 VAL H C 1 ATOM 4869 O O . VAL C 3 18 ? 68.151 36.669 93.765 1.00 27.57 ? 18 VAL H O 1 ATOM 4870 C CB . VAL C 3 18 ? 67.050 38.009 91.144 1.00 31.12 ? 18 VAL H CB 1 ATOM 4871 C CG1 . VAL C 3 18 ? 66.344 36.662 91.369 1.00 30.66 ? 18 VAL H CG1 1 ATOM 4872 C CG2 . VAL C 3 18 ? 66.249 39.214 91.621 1.00 32.57 ? 18 VAL H CG2 1 ATOM 4873 N N . LYS C 3 19 ? 68.609 38.859 94.125 1.00 26.10 ? 19 LYS H N 1 ATOM 4874 C CA . LYS C 3 19 ? 68.638 38.769 95.565 1.00 24.14 ? 19 LYS H CA 1 ATOM 4875 C C . LYS C 3 19 ? 67.427 39.601 95.986 1.00 23.37 ? 19 LYS H C 1 ATOM 4876 O O . LYS C 3 19 ? 67.347 40.812 95.711 1.00 24.58 ? 19 LYS H O 1 ATOM 4877 C CB . LYS C 3 19 ? 69.944 39.378 96.082 1.00 23.24 ? 19 LYS H CB 1 ATOM 4878 C CG . LYS C 3 19 ? 70.346 38.920 97.480 1.00 22.54 ? 19 LYS H CG 1 ATOM 4879 C CD . LYS C 3 19 ? 71.613 39.638 97.932 1.00 22.06 ? 19 LYS H CD 1 ATOM 4880 C CE . LYS C 3 19 ? 72.136 39.019 99.218 1.00 21.70 ? 19 LYS H CE 1 ATOM 4881 N NZ . LYS C 3 19 ? 73.101 39.883 99.871 1.00 21.15 ? 19 LYS H NZ 1 ATOM 4882 N N . ILE C 3 20 ? 66.439 38.881 96.535 1.00 21.22 ? 20 ILE H N 1 ATOM 4883 C CA . ILE C 3 20 ? 65.237 39.446 97.128 1.00 19.25 ? 20 ILE H CA 1 ATOM 4884 C C . ILE C 3 20 ? 65.526 39.587 98.640 1.00 18.51 ? 20 ILE H C 1 ATOM 4885 O O . ILE C 3 20 ? 66.012 38.655 99.283 1.00 17.17 ? 20 ILE H O 1 ATOM 4886 C CB . ILE C 3 20 ? 64.052 38.483 96.797 1.00 17.88 ? 20 ILE H CB 1 ATOM 4887 C CG1 . ILE C 3 20 ? 63.836 38.507 95.281 1.00 17.60 ? 20 ILE H CG1 1 ATOM 4888 C CG2 . ILE C 3 20 ? 62.784 38.878 97.570 1.00 15.10 ? 20 ILE H CG2 1 ATOM 4889 C CD1 . ILE C 3 20 ? 62.776 37.528 94.743 1.00 16.67 ? 20 ILE H CD1 1 ATOM 4890 N N . SER C 3 21 ? 65.277 40.771 99.212 1.00 18.30 ? 21 SER H N 1 ATOM 4891 C CA . SER C 3 21 ? 65.511 41.178 100.592 1.00 18.31 ? 21 SER H CA 1 ATOM 4892 C C . SER C 3 21 ? 64.185 41.107 101.321 1.00 18.35 ? 21 SER H C 1 ATOM 4893 O O . SER C 3 21 ? 63.227 41.519 100.653 1.00 19.05 ? 21 SER H O 1 ATOM 4894 C CB . SER C 3 21 ? 65.992 42.629 100.645 1.00 19.60 ? 21 SER H CB 1 ATOM 4895 O OG . SER C 3 21 ? 67.409 42.792 100.637 1.00 25.44 ? 21 SER H OG 1 ATOM 4896 N N . CYS C 3 22 ? 64.094 40.680 102.603 1.00 18.04 ? 22 CYS H N 1 ATOM 4897 C CA . CYS C 3 22 ? 62.888 40.647 103.450 1.00 15.41 ? 22 CYS H CA 1 ATOM 4898 C C . CYS C 3 22 ? 63.277 41.245 104.796 1.00 15.52 ? 22 CYS H C 1 ATOM 4899 O O . CYS C 3 22 ? 63.856 40.549 105.620 1.00 14.23 ? 22 CYS H O 1 ATOM 4900 C CB . CYS C 3 22 ? 62.431 39.185 103.562 1.00 13.87 ? 22 CYS H CB 1 ATOM 4901 S SG . CYS C 3 22 ? 61.138 38.922 104.785 1.00 12.32 ? 22 CYS H SG 1 ATOM 4902 N N . LYS C 3 23 ? 63.018 42.522 105.071 1.00 15.22 ? 23 LYS H N 1 ATOM 4903 C CA . LYS C 3 23 ? 63.561 43.232 106.234 1.00 15.36 ? 23 LYS H CA 1 ATOM 4904 C C . LYS C 3 23 ? 62.509 43.044 107.293 1.00 18.32 ? 23 LYS H C 1 ATOM 4905 O O . LYS C 3 23 ? 61.379 43.527 107.144 1.00 17.23 ? 23 LYS H O 1 ATOM 4906 C CB . LYS C 3 23 ? 63.737 44.723 105.936 1.00 15.67 ? 23 LYS H CB 1 ATOM 4907 C CG . LYS C 3 23 ? 64.685 44.997 104.779 1.00 14.99 ? 23 LYS H CG 1 ATOM 4908 C CD . LYS C 3 23 ? 64.862 46.486 104.566 1.00 14.68 ? 23 LYS H CD 1 ATOM 4909 C CE . LYS C 3 23 ? 66.040 46.675 103.630 1.00 14.52 ? 23 LYS H CE 1 ATOM 4910 N NZ . LYS C 3 23 ? 66.212 48.071 103.287 1.00 14.69 ? 23 LYS H NZ 1 ATOM 4911 N N . ALA C 3 24 ? 62.829 42.300 108.354 1.00 21.33 ? 24 ALA H N 1 ATOM 4912 C CA . ALA C 3 24 ? 61.840 41.922 109.374 1.00 22.11 ? 24 ALA H CA 1 ATOM 4913 C C . ALA C 3 24 ? 61.693 42.842 110.567 1.00 23.39 ? 24 ALA H C 1 ATOM 4914 O O . ALA C 3 24 ? 62.695 43.346 111.103 1.00 22.32 ? 24 ALA H O 1 ATOM 4915 C CB . ALA C 3 24 ? 62.165 40.534 109.908 1.00 24.21 ? 24 ALA H CB 1 ATOM 4916 N N . SER C 3 25 ? 60.478 43.059 111.049 1.00 25.56 ? 25 SER H N 1 ATOM 4917 C CA . SER C 3 25 ? 60.305 43.980 112.143 1.00 25.85 ? 25 SER H CA 1 ATOM 4918 C C . SER C 3 25 ? 59.276 43.422 113.088 1.00 23.87 ? 25 SER H C 1 ATOM 4919 O O . SER C 3 25 ? 58.548 42.455 112.833 1.00 23.93 ? 25 SER H O 1 ATOM 4920 C CB . SER C 3 25 ? 59.882 45.304 111.556 1.00 28.49 ? 25 SER H CB 1 ATOM 4921 O OG . SER C 3 25 ? 59.466 46.265 112.517 1.00 31.77 ? 25 SER H OG 1 ATOM 4922 N N . GLY C 3 26 ? 59.251 44.070 114.230 1.00 24.31 ? 26 GLY H N 1 ATOM 4923 C CA . GLY C 3 26 ? 58.303 43.707 115.243 1.00 24.86 ? 26 GLY H CA 1 ATOM 4924 C C . GLY C 3 26 ? 58.724 42.573 116.153 1.00 25.82 ? 26 GLY H C 1 ATOM 4925 O O . GLY C 3 26 ? 58.334 42.603 117.326 1.00 27.21 ? 26 GLY H O 1 ATOM 4926 N N . TYR C 3 27 ? 59.435 41.550 115.690 1.00 25.88 ? 27 TYR H N 1 ATOM 4927 C CA . TYR C 3 27 ? 59.822 40.489 116.601 1.00 25.49 ? 27 TYR H CA 1 ATOM 4928 C C . TYR C 3 27 ? 61.339 40.418 116.851 1.00 25.24 ? 27 TYR H C 1 ATOM 4929 O O . TYR C 3 27 ? 62.051 41.369 116.511 1.00 25.36 ? 27 TYR H O 1 ATOM 4930 C CB . TYR C 3 27 ? 59.237 39.211 116.023 1.00 23.18 ? 27 TYR H CB 1 ATOM 4931 C CG . TYR C 3 27 ? 59.854 38.795 114.729 1.00 21.69 ? 27 TYR H CG 1 ATOM 4932 C CD1 . TYR C 3 27 ? 59.497 39.362 113.539 1.00 21.33 ? 27 TYR H CD1 1 ATOM 4933 C CD2 . TYR C 3 27 ? 60.810 37.825 114.803 1.00 21.02 ? 27 TYR H CD2 1 ATOM 4934 C CE1 . TYR C 3 27 ? 60.125 38.929 112.395 1.00 20.99 ? 27 TYR H CE1 1 ATOM 4935 C CE2 . TYR C 3 27 ? 61.441 37.387 113.670 1.00 20.59 ? 27 TYR H CE2 1 ATOM 4936 C CZ . TYR C 3 27 ? 61.097 37.943 112.473 1.00 20.52 ? 27 TYR H CZ 1 ATOM 4937 O OH . TYR C 3 27 ? 61.759 37.471 111.362 1.00 18.80 ? 27 TYR H OH 1 ATOM 4938 N N . THR C 3 28 ? 61.929 39.390 117.474 1.00 26.14 ? 28 THR H N 1 ATOM 4939 C CA . THR C 3 28 ? 63.378 39.353 117.658 1.00 28.81 ? 28 THR H CA 1 ATOM 4940 C C . THR C 3 28 ? 63.939 38.330 116.690 1.00 28.89 ? 28 THR H C 1 ATOM 4941 O O . THR C 3 28 ? 63.767 37.118 116.868 1.00 29.85 ? 28 THR H O 1 ATOM 4942 C CB . THR C 3 28 ? 63.745 38.932 119.095 1.00 29.07 ? 28 THR H CB 1 ATOM 4943 O OG1 . THR C 3 28 ? 62.896 39.668 120.004 1.00 31.67 ? 28 THR H OG1 1 ATOM 4944 C CG2 . THR C 3 28 ? 65.256 39.119 119.320 1.00 28.53 ? 28 THR H CG2 1 ATOM 4945 N N . PHE C 3 29 ? 64.685 38.819 115.703 1.00 29.30 ? 29 PHE H N 1 ATOM 4946 C CA . PHE C 3 29 ? 65.127 37.996 114.587 1.00 29.92 ? 29 PHE H CA 1 ATOM 4947 C C . PHE C 3 29 ? 65.736 36.625 114.886 1.00 32.16 ? 29 PHE H C 1 ATOM 4948 O O . PHE C 3 29 ? 65.350 35.604 114.316 1.00 34.84 ? 29 PHE H O 1 ATOM 4949 C CB . PHE C 3 29 ? 66.086 38.851 113.808 1.00 28.19 ? 29 PHE H CB 1 ATOM 4950 C CG . PHE C 3 29 ? 66.194 38.503 112.343 1.00 26.03 ? 29 PHE H CG 1 ATOM 4951 C CD1 . PHE C 3 29 ? 65.056 38.419 111.581 1.00 25.06 ? 29 PHE H CD1 1 ATOM 4952 C CD2 . PHE C 3 29 ? 67.443 38.312 111.792 1.00 25.88 ? 29 PHE H CD2 1 ATOM 4953 C CE1 . PHE C 3 29 ? 65.184 38.145 110.247 1.00 25.30 ? 29 PHE H CE1 1 ATOM 4954 C CE2 . PHE C 3 29 ? 67.559 38.045 110.450 1.00 25.47 ? 29 PHE H CE2 1 ATOM 4955 C CZ . PHE C 3 29 ? 66.428 37.959 109.680 1.00 25.49 ? 29 PHE H CZ 1 ATOM 4956 N N . THR C 3 30 ? 66.631 36.673 115.862 1.00 33.85 ? 30 THR H N 1 ATOM 4957 C CA . THR C 3 30 ? 67.419 35.592 116.431 1.00 34.46 ? 30 THR H CA 1 ATOM 4958 C C . THR C 3 30 ? 66.647 34.403 117.008 1.00 33.89 ? 30 THR H C 1 ATOM 4959 O O . THR C 3 30 ? 67.236 33.332 117.212 1.00 34.77 ? 30 THR H O 1 ATOM 4960 C CB . THR C 3 30 ? 68.289 36.272 117.496 1.00 35.09 ? 30 THR H CB 1 ATOM 4961 O OG1 . THR C 3 30 ? 68.700 37.493 116.876 1.00 36.90 ? 30 THR H OG1 1 ATOM 4962 C CG2 . THR C 3 30 ? 69.517 35.504 117.951 1.00 37.48 ? 30 THR H CG2 1 ATOM 4963 N N . ASN C 3 31 ? 65.367 34.581 117.345 1.00 33.04 ? 31 ASN H N 1 ATOM 4964 C CA . ASN C 3 31 ? 64.562 33.520 117.948 1.00 31.81 ? 31 ASN H CA 1 ATOM 4965 C C . ASN C 3 31 ? 63.580 32.799 117.025 1.00 26.92 ? 31 ASN H C 1 ATOM 4966 O O . ASN C 3 31 ? 62.869 31.884 117.452 1.00 27.45 ? 31 ASN H O 1 ATOM 4967 C CB . ASN C 3 31 ? 63.778 34.109 119.099 1.00 36.89 ? 31 ASN H CB 1 ATOM 4968 C CG . ASN C 3 31 ? 63.967 33.388 120.429 1.00 42.28 ? 31 ASN H CG 1 ATOM 4969 O OD1 . ASN C 3 31 ? 64.339 32.207 120.568 1.00 43.94 ? 31 ASN H OD1 1 ATOM 4970 N ND2 . ASN C 3 31 ? 63.676 34.164 121.475 1.00 44.00 ? 31 ASN H ND2 1 ATOM 4971 N N . TYR C 3 32 ? 63.483 33.244 115.758 1.00 21.11 ? 32 TYR H N 1 ATOM 4972 C CA . TYR C 3 32 ? 62.500 32.812 114.773 1.00 16.09 ? 32 TYR H CA 1 ATOM 4973 C C . TYR C 3 32 ? 63.138 32.812 113.399 1.00 14.28 ? 32 TYR H C 1 ATOM 4974 O O . TYR C 3 32 ? 63.468 33.851 112.806 1.00 13.58 ? 32 TYR H O 1 ATOM 4975 C CB . TYR C 3 32 ? 61.317 33.772 114.750 1.00 13.64 ? 32 TYR H CB 1 ATOM 4976 C CG . TYR C 3 32 ? 60.481 33.661 116.002 1.00 13.41 ? 32 TYR H CG 1 ATOM 4977 C CD1 . TYR C 3 32 ? 59.564 32.621 116.113 1.00 12.70 ? 32 TYR H CD1 1 ATOM 4978 C CD2 . TYR C 3 32 ? 60.663 34.557 117.033 1.00 12.02 ? 32 TYR H CD2 1 ATOM 4979 C CE1 . TYR C 3 32 ? 58.817 32.477 117.284 1.00 13.24 ? 32 TYR H CE1 1 ATOM 4980 C CE2 . TYR C 3 32 ? 59.921 34.395 118.178 1.00 12.06 ? 32 TYR H CE2 1 ATOM 4981 C CZ . TYR C 3 32 ? 59.003 33.367 118.315 1.00 12.92 ? 32 TYR H CZ 1 ATOM 4982 O OH . TYR C 3 32 ? 58.267 33.262 119.486 1.00 16.53 ? 32 TYR H OH 1 ATOM 4983 N N . GLY C 3 33 ? 63.310 31.587 112.916 1.00 13.21 ? 33 GLY H N 1 ATOM 4984 C CA . GLY C 3 33 ? 63.900 31.432 111.612 1.00 14.01 ? 33 GLY H CA 1 ATOM 4985 C C . GLY C 3 33 ? 62.959 31.903 110.537 1.00 15.29 ? 33 GLY H C 1 ATOM 4986 O O . GLY C 3 33 ? 61.785 32.157 110.814 1.00 16.87 ? 33 GLY H O 1 ATOM 4987 N N . MET C 3 34 ? 63.450 31.993 109.303 1.00 13.78 ? 34 MET H N 1 ATOM 4988 C CA . MET C 3 34 ? 62.661 32.455 108.152 1.00 10.90 ? 34 MET H CA 1 ATOM 4989 C C . MET C 3 34 ? 62.168 31.369 107.233 1.00 11.81 ? 34 MET H C 1 ATOM 4990 O O . MET C 3 34 ? 62.919 30.436 106.995 1.00 14.92 ? 34 MET H O 1 ATOM 4991 C CB . MET C 3 34 ? 63.425 33.389 107.218 1.00 9.67 ? 34 MET H CB 1 ATOM 4992 C CG . MET C 3 34 ? 63.207 34.876 107.469 1.00 9.49 ? 34 MET H CG 1 ATOM 4993 S SD . MET C 3 34 ? 61.494 35.442 107.275 1.00 6.54 ? 34 MET H SD 1 ATOM 4994 C CE . MET C 3 34 ? 61.695 36.878 108.309 1.00 11.12 ? 34 MET H CE 1 ATOM 4995 N N . ASN C 3 35 ? 60.968 31.466 106.698 1.00 11.02 ? 35 ASN H N 1 ATOM 4996 C CA . ASN C 3 35 ? 60.494 30.539 105.708 1.00 9.82 ? 35 ASN H CA 1 ATOM 4997 C C . ASN C 3 35 ? 60.501 31.363 104.474 1.00 8.90 ? 35 ASN H C 1 ATOM 4998 O O . ASN C 3 35 ? 60.227 32.565 104.548 1.00 11.19 ? 35 ASN H O 1 ATOM 4999 C CB . ASN C 3 35 ? 59.066 30.099 105.878 1.00 12.88 ? 35 ASN H CB 1 ATOM 5000 C CG . ASN C 3 35 ? 58.891 28.841 106.708 1.00 16.87 ? 35 ASN H CG 1 ATOM 5001 O OD1 . ASN C 3 35 ? 59.826 28.220 107.218 1.00 19.07 ? 35 ASN H OD1 1 ATOM 5002 N ND2 . ASN C 3 35 ? 57.660 28.388 106.855 1.00 17.06 ? 35 ASN H ND2 1 ATOM 5003 N N . TRP C 3 36 ? 60.857 30.740 103.365 1.00 7.00 ? 36 TRP H N 1 ATOM 5004 C CA . TRP C 3 36 ? 60.664 31.309 102.032 1.00 5.53 ? 36 TRP H CA 1 ATOM 5005 C C . TRP C 3 36 ? 59.617 30.511 101.255 1.00 7.87 ? 36 TRP H C 1 ATOM 5006 O O . TRP C 3 36 ? 59.745 29.300 101.149 1.00 10.46 ? 36 TRP H O 1 ATOM 5007 C CB . TRP C 3 36 ? 61.953 31.293 101.248 1.00 6.40 ? 36 TRP H CB 1 ATOM 5008 C CG . TRP C 3 36 ? 62.878 32.428 101.641 1.00 7.52 ? 36 TRP H CG 1 ATOM 5009 C CD1 . TRP C 3 36 ? 64.014 32.181 102.347 1.00 8.09 ? 36 TRP H CD1 1 ATOM 5010 C CD2 . TRP C 3 36 ? 62.720 33.756 101.382 1.00 8.61 ? 36 TRP H CD2 1 ATOM 5011 N NE1 . TRP C 3 36 ? 64.574 33.345 102.546 1.00 10.15 ? 36 TRP H NE1 1 ATOM 5012 C CE2 . TRP C 3 36 ? 63.830 34.309 101.993 1.00 8.99 ? 36 TRP H CE2 1 ATOM 5013 C CE3 . TRP C 3 36 ? 61.795 34.532 100.738 1.00 10.60 ? 36 TRP H CE3 1 ATOM 5014 C CZ2 . TRP C 3 36 ? 64.025 35.667 101.960 1.00 10.21 ? 36 TRP H CZ2 1 ATOM 5015 C CZ3 . TRP C 3 36 ? 62.002 35.887 100.711 1.00 10.00 ? 36 TRP H CZ3 1 ATOM 5016 C CH2 . TRP C 3 36 ? 63.097 36.455 101.311 1.00 10.38 ? 36 TRP H CH2 1 ATOM 5017 N N . VAL C 3 37 ? 58.530 31.049 100.722 1.00 10.74 ? 37 VAL H N 1 ATOM 5018 C CA . VAL C 3 37 ? 57.553 30.285 99.951 1.00 10.29 ? 37 VAL H CA 1 ATOM 5019 C C . VAL C 3 37 ? 57.443 30.754 98.470 1.00 12.56 ? 37 VAL H C 1 ATOM 5020 O O . VAL C 3 37 ? 57.801 31.890 98.139 1.00 10.34 ? 37 VAL H O 1 ATOM 5021 C CB . VAL C 3 37 ? 56.259 30.403 100.814 1.00 7.29 ? 37 VAL H CB 1 ATOM 5022 C CG1 . VAL C 3 37 ? 54.982 29.856 100.228 1.00 6.65 ? 37 VAL H CG1 1 ATOM 5023 C CG2 . VAL C 3 37 ? 56.498 29.463 101.978 1.00 2.87 ? 37 VAL H CG2 1 ATOM 5024 N N . LYS C 3 38 ? 57.016 29.895 97.523 1.00 16.75 ? 38 LYS H N 1 ATOM 5025 C CA . LYS C 3 38 ? 56.855 30.219 96.103 1.00 22.66 ? 38 LYS H CA 1 ATOM 5026 C C . LYS C 3 38 ? 55.380 30.218 95.759 1.00 22.76 ? 38 LYS H C 1 ATOM 5027 O O . LYS C 3 38 ? 54.702 29.232 96.003 1.00 24.34 ? 38 LYS H O 1 ATOM 5028 C CB . LYS C 3 38 ? 57.557 29.173 95.225 1.00 26.33 ? 38 LYS H CB 1 ATOM 5029 C CG . LYS C 3 38 ? 57.615 29.345 93.692 1.00 30.75 ? 38 LYS H CG 1 ATOM 5030 C CD . LYS C 3 38 ? 58.273 28.099 93.060 1.00 34.56 ? 38 LYS H CD 1 ATOM 5031 C CE . LYS C 3 38 ? 58.797 28.274 91.620 1.00 35.86 ? 38 LYS H CE 1 ATOM 5032 N NZ . LYS C 3 38 ? 59.539 27.092 91.202 1.00 38.77 ? 38 LYS H NZ 1 ATOM 5033 N N . GLN C 3 39 ? 54.832 31.282 95.220 1.00 24.24 ? 39 GLN H N 1 ATOM 5034 C CA . GLN C 3 39 ? 53.452 31.289 94.809 1.00 26.09 ? 39 GLN H CA 1 ATOM 5035 C C . GLN C 3 39 ? 53.719 31.452 93.349 1.00 27.11 ? 39 GLN H C 1 ATOM 5036 O O . GLN C 3 39 ? 54.190 32.485 92.839 1.00 29.58 ? 39 GLN H O 1 ATOM 5037 C CB . GLN C 3 39 ? 52.656 32.519 95.252 1.00 27.71 ? 39 GLN H CB 1 ATOM 5038 C CG . GLN C 3 39 ? 51.209 32.589 94.781 1.00 32.70 ? 39 GLN H CG 1 ATOM 5039 C CD . GLN C 3 39 ? 50.216 31.813 95.638 1.00 35.24 ? 39 GLN H CD 1 ATOM 5040 O OE1 . GLN C 3 39 ? 50.084 30.590 95.616 1.00 36.15 ? 39 GLN H OE1 1 ATOM 5041 N NE2 . GLN C 3 39 ? 49.459 32.564 96.416 1.00 39.29 ? 39 GLN H NE2 1 ATOM 5042 N N . ALA C 3 40 ? 53.502 30.314 92.723 1.00 29.47 ? 40 ALA H N 1 ATOM 5043 C CA . ALA C 3 40 ? 53.507 30.327 91.271 1.00 30.69 ? 40 ALA H CA 1 ATOM 5044 C C . ALA C 3 40 ? 52.178 30.970 90.917 1.00 31.93 ? 40 ALA H C 1 ATOM 5045 O O . ALA C 3 40 ? 51.302 31.047 91.798 1.00 33.63 ? 40 ALA H O 1 ATOM 5046 C CB . ALA C 3 40 ? 53.472 28.950 90.700 1.00 32.27 ? 40 ALA H CB 1 ATOM 5047 N N . PRO C 3 41 ? 51.903 31.444 89.697 1.00 33.15 ? 41 PRO H N 1 ATOM 5048 C CA . PRO C 3 41 ? 50.523 31.823 89.339 1.00 33.53 ? 41 PRO H CA 1 ATOM 5049 C C . PRO C 3 41 ? 49.600 30.596 89.229 1.00 32.92 ? 41 PRO H C 1 ATOM 5050 O O . PRO C 3 41 ? 48.734 30.371 90.090 1.00 35.66 ? 41 PRO H O 1 ATOM 5051 C CB . PRO C 3 41 ? 50.726 32.630 88.064 1.00 33.82 ? 41 PRO H CB 1 ATOM 5052 C CG . PRO C 3 41 ? 52.101 33.268 88.301 1.00 35.11 ? 41 PRO H CG 1 ATOM 5053 C CD . PRO C 3 41 ? 52.886 32.046 88.793 1.00 34.87 ? 41 PRO H CD 1 ATOM 5054 N N . GLY C 3 42 ? 49.804 29.698 88.273 1.00 31.61 ? 42 GLY H N 1 ATOM 5055 C CA . GLY C 3 42 ? 48.927 28.547 88.166 1.00 29.75 ? 42 GLY H CA 1 ATOM 5056 C C . GLY C 3 42 ? 49.446 27.380 88.985 1.00 29.02 ? 42 GLY H C 1 ATOM 5057 O O . GLY C 3 42 ? 49.912 26.428 88.367 1.00 28.69 ? 42 GLY H O 1 ATOM 5058 N N . LYS C 3 43 ? 49.440 27.411 90.326 1.00 28.17 ? 43 LYS H N 1 ATOM 5059 C CA . LYS C 3 43 ? 49.895 26.271 91.122 1.00 27.32 ? 43 LYS H CA 1 ATOM 5060 C C . LYS C 3 43 ? 49.655 26.373 92.623 1.00 26.89 ? 43 LYS H C 1 ATOM 5061 O O . LYS C 3 43 ? 49.504 25.321 93.246 1.00 27.51 ? 43 LYS H O 1 ATOM 5062 C CB . LYS C 3 43 ? 51.399 26.017 90.935 1.00 27.00 ? 43 LYS H CB 1 ATOM 5063 C CG . LYS C 3 43 ? 51.959 24.614 91.216 1.00 26.48 ? 43 LYS H CG 1 ATOM 5064 C CD . LYS C 3 43 ? 51.775 23.593 90.084 1.00 26.10 ? 43 LYS H CD 1 ATOM 5065 C CE . LYS C 3 43 ? 50.439 22.857 90.103 1.00 25.92 ? 43 LYS H CE 1 ATOM 5066 N NZ . LYS C 3 43 ? 50.351 21.921 88.997 1.00 25.90 ? 43 LYS H NZ 1 ATOM 5067 N N . GLY C 3 44 ? 49.566 27.535 93.275 1.00 26.62 ? 44 GLY H N 1 ATOM 5068 C CA . GLY C 3 44 ? 49.419 27.502 94.734 1.00 25.20 ? 44 GLY H CA 1 ATOM 5069 C C . GLY C 3 44 ? 50.758 27.461 95.500 1.00 23.45 ? 44 GLY H C 1 ATOM 5070 O O . GLY C 3 44 ? 51.841 27.641 94.913 1.00 25.92 ? 44 GLY H O 1 ATOM 5071 N N . LEU C 3 45 ? 50.707 27.159 96.814 1.00 19.89 ? 45 LEU H N 1 ATOM 5072 C CA . LEU C 3 45 ? 51.855 27.384 97.669 1.00 17.31 ? 45 LEU H CA 1 ATOM 5073 C C . LEU C 3 45 ? 52.859 26.256 97.801 1.00 18.51 ? 45 LEU H C 1 ATOM 5074 O O . LEU C 3 45 ? 52.515 25.077 97.880 1.00 19.00 ? 45 LEU H O 1 ATOM 5075 C CB . LEU C 3 45 ? 51.311 27.801 99.000 1.00 12.99 ? 45 LEU H CB 1 ATOM 5076 C CG . LEU C 3 45 ? 50.692 29.199 99.071 1.00 10.44 ? 45 LEU H CG 1 ATOM 5077 C CD1 . LEU C 3 45 ? 50.281 29.504 100.486 1.00 6.37 ? 45 LEU H CD1 1 ATOM 5078 C CD2 . LEU C 3 45 ? 51.705 30.283 98.802 1.00 8.93 ? 45 LEU H CD2 1 ATOM 5079 N N . GLU C 3 46 ? 54.136 26.649 97.798 1.00 20.70 ? 46 GLU H N 1 ATOM 5080 C CA . GLU C 3 46 ? 55.313 25.782 97.850 1.00 23.38 ? 46 GLU H CA 1 ATOM 5081 C C . GLU C 3 46 ? 56.264 26.161 99.004 1.00 22.93 ? 46 GLU H C 1 ATOM 5082 O O . GLU C 3 46 ? 56.719 27.311 98.993 1.00 25.02 ? 46 GLU H O 1 ATOM 5083 C CB . GLU C 3 46 ? 56.057 25.910 96.535 1.00 25.95 ? 46 GLU H CB 1 ATOM 5084 C CG . GLU C 3 46 ? 57.134 24.849 96.360 1.00 30.37 ? 46 GLU H CG 1 ATOM 5085 C CD . GLU C 3 46 ? 56.779 23.639 95.469 1.00 33.26 ? 46 GLU H CD 1 ATOM 5086 O OE1 . GLU C 3 46 ? 55.628 23.517 95.050 1.00 36.37 ? 46 GLU H OE1 1 ATOM 5087 O OE2 . GLU C 3 46 ? 57.653 22.809 95.172 1.00 34.32 ? 46 GLU H OE2 1 ATOM 5088 N N . TRP C 3 47 ? 56.567 25.353 100.042 1.00 21.80 ? 47 TRP H N 1 ATOM 5089 C CA . TRP C 3 47 ? 57.568 25.723 101.038 1.00 19.68 ? 47 TRP H CA 1 ATOM 5090 C C . TRP C 3 47 ? 58.910 25.653 100.299 1.00 18.84 ? 47 TRP H C 1 ATOM 5091 O O . TRP C 3 47 ? 59.175 24.632 99.661 1.00 21.32 ? 47 TRP H O 1 ATOM 5092 C CB . TRP C 3 47 ? 57.514 24.727 102.216 1.00 19.10 ? 47 TRP H CB 1 ATOM 5093 C CG . TRP C 3 47 ? 58.549 24.965 103.326 1.00 20.43 ? 47 TRP H CG 1 ATOM 5094 C CD1 . TRP C 3 47 ? 58.529 26.087 104.108 1.00 20.44 ? 47 TRP H CD1 1 ATOM 5095 C CD2 . TRP C 3 47 ? 59.600 24.151 103.669 1.00 19.50 ? 47 TRP H CD2 1 ATOM 5096 N NE1 . TRP C 3 47 ? 59.549 25.994 104.923 1.00 18.39 ? 47 TRP H NE1 1 ATOM 5097 C CE2 . TRP C 3 47 ? 60.209 24.862 104.689 1.00 19.49 ? 47 TRP H CE2 1 ATOM 5098 C CE3 . TRP C 3 47 ? 60.133 22.937 103.270 1.00 19.27 ? 47 TRP H CE3 1 ATOM 5099 C CZ2 . TRP C 3 47 ? 61.336 24.373 105.323 1.00 21.00 ? 47 TRP H CZ2 1 ATOM 5100 C CZ3 . TRP C 3 47 ? 61.257 22.438 103.899 1.00 19.75 ? 47 TRP H CZ3 1 ATOM 5101 C CH2 . TRP C 3 47 ? 61.861 23.157 104.919 1.00 19.30 ? 47 TRP H CH2 1 ATOM 5102 N N . MET C 3 48 ? 59.727 26.717 100.216 1.00 17.95 ? 48 MET H N 1 ATOM 5103 C CA . MET C 3 48 ? 61.068 26.658 99.608 1.00 17.58 ? 48 MET H CA 1 ATOM 5104 C C . MET C 3 48 ? 62.174 26.193 100.571 1.00 17.52 ? 48 MET H C 1 ATOM 5105 O O . MET C 3 48 ? 63.166 25.544 100.215 1.00 18.73 ? 48 MET H O 1 ATOM 5106 C CB . MET C 3 48 ? 61.495 28.011 99.083 1.00 15.96 ? 48 MET H CB 1 ATOM 5107 C CG . MET C 3 48 ? 60.616 28.760 98.098 1.00 14.13 ? 48 MET H CG 1 ATOM 5108 S SD . MET C 3 48 ? 61.663 30.031 97.329 1.00 16.38 ? 48 MET H SD 1 ATOM 5109 C CE . MET C 3 48 ? 61.975 29.041 95.913 1.00 19.10 ? 48 MET H CE 1 ATOM 5110 N N . GLY C 3 49 ? 62.032 26.589 101.824 1.00 17.60 ? 49 GLY H N 1 ATOM 5111 C CA . GLY C 3 49 ? 62.923 26.209 102.902 1.00 14.76 ? 49 GLY H CA 1 ATOM 5112 C C . GLY C 3 49 ? 62.803 27.163 104.098 1.00 13.45 ? 49 GLY H C 1 ATOM 5113 O O . GLY C 3 49 ? 61.931 28.059 104.151 1.00 15.25 ? 49 GLY H O 1 ATOM 5114 N N . TRP C 3 50 ? 63.761 26.954 105.007 1.00 11.69 ? 50 TRP H N 1 ATOM 5115 C CA . TRP C 3 50 ? 63.858 27.735 106.219 1.00 9.75 ? 50 TRP H CA 1 ATOM 5116 C C . TRP C 3 50 ? 65.313 28.016 106.581 1.00 9.98 ? 50 TRP H C 1 ATOM 5117 O O . TRP C 3 50 ? 66.185 27.195 106.285 1.00 7.07 ? 50 TRP H O 1 ATOM 5118 C CB . TRP C 3 50 ? 63.131 26.959 107.306 1.00 8.51 ? 50 TRP H CB 1 ATOM 5119 C CG . TRP C 3 50 ? 63.211 27.517 108.709 1.00 7.03 ? 50 TRP H CG 1 ATOM 5120 C CD1 . TRP C 3 50 ? 62.376 28.492 109.173 1.00 6.57 ? 50 TRP H CD1 1 ATOM 5121 C CD2 . TRP C 3 50 ? 64.072 27.069 109.659 1.00 6.36 ? 50 TRP H CD2 1 ATOM 5122 N NE1 . TRP C 3 50 ? 62.708 28.643 110.433 1.00 5.98 ? 50 TRP H NE1 1 ATOM 5123 C CE2 . TRP C 3 50 ? 63.703 27.812 110.749 1.00 6.28 ? 50 TRP H CE2 1 ATOM 5124 C CE3 . TRP C 3 50 ? 65.089 26.148 109.747 1.00 3.85 ? 50 TRP H CE3 1 ATOM 5125 C CZ2 . TRP C 3 50 ? 64.330 27.665 111.947 1.00 4.77 ? 50 TRP H CZ2 1 ATOM 5126 C CZ3 . TRP C 3 50 ? 65.728 25.989 110.956 1.00 2.06 ? 50 TRP H CZ3 1 ATOM 5127 C CH2 . TRP C 3 50 ? 65.341 26.738 112.039 1.00 2.31 ? 50 TRP H CH2 1 ATOM 5128 N N . ILE C 3 51 ? 65.618 29.186 107.160 1.00 9.25 ? 51 ILE H N 1 ATOM 5129 C CA . ILE C 3 51 ? 66.952 29.506 107.628 1.00 9.24 ? 51 ILE H CA 1 ATOM 5130 C C . ILE C 3 51 ? 66.997 29.786 109.146 1.00 9.72 ? 51 ILE H C 1 ATOM 5131 O O . ILE C 3 51 ? 66.234 30.583 109.702 1.00 8.65 ? 51 ILE H O 1 ATOM 5132 C CB . ILE C 3 51 ? 67.510 30.703 106.829 1.00 9.16 ? 51 ILE H CB 1 ATOM 5133 C CG1 . ILE C 3 51 ? 68.967 30.857 107.253 1.00 8.00 ? 51 ILE H CG1 1 ATOM 5134 C CG2 . ILE C 3 51 ? 66.749 32.005 107.048 1.00 7.97 ? 51 ILE H CG2 1 ATOM 5135 C CD1 . ILE C 3 51 ? 69.819 31.470 106.127 1.00 7.44 ? 51 ILE H CD1 1 ATOM 5136 N N . ASN C 3 52 ? 67.865 29.106 109.888 1.00 10.26 ? 52 ASN H N 1 ATOM 5137 C CA . ASN C 3 52 ? 68.032 29.314 111.301 1.00 9.43 ? 52 ASN H CA 1 ATOM 5138 C C . ASN C 3 52 ? 68.631 30.719 111.421 1.00 9.07 ? 52 ASN H C 1 ATOM 5139 O O . ASN C 3 52 ? 69.825 30.883 111.192 1.00 10.36 ? 52 ASN H O 1 ATOM 5140 C CB . ASN C 3 52 ? 68.960 28.206 111.764 1.00 9.98 ? 52 ASN H CB 1 ATOM 5141 C CG . ASN C 3 52 ? 69.043 28.068 113.264 1.00 11.67 ? 52 ASN H CG 1 ATOM 5142 O OD1 . ASN C 3 52 ? 69.351 29.036 113.955 1.00 11.22 ? 52 ASN H OD1 1 ATOM 5143 N ND2 . ASN C 3 52 ? 68.759 26.907 113.847 1.00 13.77 ? 52 ASN H ND2 1 ATOM 5144 N N . THR C 3 53 A 67.877 31.773 111.762 1.00 9.96 ? 52 THR H N 1 ATOM 5145 C CA . THR C 3 53 A 68.368 33.145 111.840 1.00 11.91 ? 52 THR H CA 1 ATOM 5146 C C . THR C 3 53 A 69.325 33.330 113.007 1.00 14.79 ? 52 THR H C 1 ATOM 5147 O O . THR C 3 53 A 69.847 34.415 113.293 1.00 17.43 ? 52 THR H O 1 ATOM 5148 C CB . THR C 3 53 A 67.157 34.094 111.960 1.00 11.51 ? 52 THR H CB 1 ATOM 5149 O OG1 . THR C 3 53 A 66.378 33.558 113.014 1.00 15.45 ? 52 THR H OG1 1 ATOM 5150 C CG2 . THR C 3 53 A 66.248 34.155 110.754 1.00 13.55 ? 52 THR H CG2 1 ATOM 5151 N N . ASN C 3 54 ? 69.513 32.251 113.760 1.00 16.94 ? 53 ASN H N 1 ATOM 5152 C CA . ASN C 3 54 ? 70.423 32.220 114.891 1.00 18.99 ? 53 ASN H CA 1 ATOM 5153 C C . ASN C 3 54 ? 71.801 31.659 114.548 1.00 19.08 ? 53 ASN H C 1 ATOM 5154 O O . ASN C 3 54 ? 72.820 32.256 114.896 1.00 18.07 ? 53 ASN H O 1 ATOM 5155 C CB . ASN C 3 54 ? 69.798 31.390 115.997 1.00 20.62 ? 53 ASN H CB 1 ATOM 5156 C CG . ASN C 3 54 ? 70.708 31.411 117.194 1.00 23.63 ? 53 ASN H CG 1 ATOM 5157 O OD1 . ASN C 3 54 ? 71.525 30.521 117.419 1.00 26.47 ? 53 ASN H OD1 1 ATOM 5158 N ND2 . ASN C 3 54 ? 70.550 32.458 117.980 1.00 23.91 ? 53 ASN H ND2 1 ATOM 5159 N N . THR C 3 55 ? 71.815 30.469 113.927 1.00 20.28 ? 54 THR H N 1 ATOM 5160 C CA . THR C 3 55 ? 73.037 29.769 113.526 1.00 18.45 ? 54 THR H CA 1 ATOM 5161 C C . THR C 3 55 ? 73.485 30.090 112.107 1.00 20.80 ? 54 THR H C 1 ATOM 5162 O O . THR C 3 55 ? 74.615 29.793 111.704 1.00 22.29 ? 54 THR H O 1 ATOM 5163 C CB . THR C 3 55 ? 72.883 28.220 113.594 1.00 15.05 ? 54 THR H CB 1 ATOM 5164 O OG1 . THR C 3 55 ? 71.929 27.802 112.620 1.00 12.21 ? 54 THR H OG1 1 ATOM 5165 C CG2 . THR C 3 55 ? 72.383 27.755 114.914 1.00 14.56 ? 54 THR H CG2 1 ATOM 5166 N N . GLY C 3 56 ? 72.505 30.606 111.349 1.00 21.70 ? 55 GLY H N 1 ATOM 5167 C CA . GLY C 3 56 ? 72.617 30.920 109.942 1.00 21.09 ? 55 GLY H CA 1 ATOM 5168 C C . GLY C 3 56 ? 72.392 29.727 109.019 1.00 21.43 ? 55 GLY H C 1 ATOM 5169 O O . GLY C 3 56 ? 72.382 29.948 107.805 1.00 20.41 ? 55 GLY H O 1 ATOM 5170 N N . GLU C 3 57 ? 72.161 28.472 109.450 1.00 21.97 ? 56 GLU H N 1 ATOM 5171 C CA . GLU C 3 57 ? 72.135 27.411 108.450 1.00 22.48 ? 56 GLU H CA 1 ATOM 5172 C C . GLU C 3 57 ? 70.784 26.935 107.985 1.00 20.93 ? 56 GLU H C 1 ATOM 5173 O O . GLU C 3 57 ? 69.852 26.804 108.778 1.00 22.41 ? 56 GLU H O 1 ATOM 5174 C CB . GLU C 3 57 ? 72.978 26.176 108.912 1.00 25.97 ? 56 GLU H CB 1 ATOM 5175 C CG . GLU C 3 57 ? 73.207 25.893 110.395 1.00 31.30 ? 56 GLU H CG 1 ATOM 5176 C CD . GLU C 3 57 ? 72.532 24.631 110.980 1.00 33.35 ? 56 GLU H CD 1 ATOM 5177 O OE1 . GLU C 3 57 ? 72.485 23.602 110.276 1.00 34.16 ? 56 GLU H OE1 1 ATOM 5178 O OE2 . GLU C 3 57 ? 72.074 24.677 112.149 1.00 35.29 ? 56 GLU H OE2 1 ATOM 5179 N N . PRO C 3 58 ? 70.668 26.752 106.661 1.00 19.34 ? 57 PRO H N 1 ATOM 5180 C CA . PRO C 3 58 ? 69.421 26.598 105.924 1.00 17.62 ? 57 PRO H CA 1 ATOM 5181 C C . PRO C 3 58 ? 69.059 25.180 105.529 1.00 16.57 ? 57 PRO H C 1 ATOM 5182 O O . PRO C 3 58 ? 69.912 24.320 105.318 1.00 17.68 ? 57 PRO H O 1 ATOM 5183 C CB . PRO C 3 58 ? 69.597 27.524 104.716 1.00 17.03 ? 57 PRO H CB 1 ATOM 5184 C CG . PRO C 3 58 ? 71.096 27.648 104.460 1.00 16.77 ? 57 PRO H CG 1 ATOM 5185 C CD . PRO C 3 58 ? 71.737 26.914 105.662 1.00 18.68 ? 57 PRO H CD 1 ATOM 5186 N N . THR C 3 59 ? 67.778 24.923 105.440 1.00 15.94 ? 58 THR H N 1 ATOM 5187 C CA . THR C 3 59 ? 67.282 23.644 105.033 1.00 16.11 ? 58 THR H CA 1 ATOM 5188 C C . THR C 3 59 ? 66.582 24.002 103.763 1.00 17.81 ? 58 THR H C 1 ATOM 5189 O O . THR C 3 59 ? 65.714 24.878 103.851 1.00 18.71 ? 58 THR H O 1 ATOM 5190 C CB . THR C 3 59 ? 66.294 23.185 106.016 1.00 13.96 ? 58 THR H CB 1 ATOM 5191 O OG1 . THR C 3 59 ? 66.883 23.419 107.298 1.00 17.81 ? 58 THR H OG1 1 ATOM 5192 C CG2 . THR C 3 59 ? 65.911 21.753 105.817 1.00 13.88 ? 58 THR H CG2 1 ATOM 5193 N N . TYR C 3 60 ? 66.969 23.441 102.607 1.00 17.41 ? 59 TYR H N 1 ATOM 5194 C CA . TYR C 3 60 ? 66.265 23.664 101.334 1.00 15.96 ? 59 TYR H CA 1 ATOM 5195 C C . TYR C 3 60 ? 65.284 22.557 101.025 1.00 16.12 ? 59 TYR H C 1 ATOM 5196 O O . TYR C 3 60 ? 65.371 21.417 101.490 1.00 15.66 ? 59 TYR H O 1 ATOM 5197 C CB . TYR C 3 60 ? 67.213 23.742 100.136 1.00 14.02 ? 59 TYR H CB 1 ATOM 5198 C CG . TYR C 3 60 ? 68.113 24.934 100.331 1.00 12.81 ? 59 TYR H CG 1 ATOM 5199 C CD1 . TYR C 3 60 ? 67.525 26.158 100.376 1.00 12.64 ? 59 TYR H CD1 1 ATOM 5200 C CD2 . TYR C 3 60 ? 69.464 24.822 100.547 1.00 13.05 ? 59 TYR H CD2 1 ATOM 5201 C CE1 . TYR C 3 60 ? 68.269 27.277 100.634 1.00 11.57 ? 59 TYR H CE1 1 ATOM 5202 C CE2 . TYR C 3 60 ? 70.218 25.947 100.812 1.00 14.35 ? 59 TYR H CE2 1 ATOM 5203 C CZ . TYR C 3 60 ? 69.598 27.175 100.867 1.00 12.69 ? 59 TYR H CZ 1 ATOM 5204 O OH . TYR C 3 60 ? 70.257 28.347 101.206 1.00 12.53 ? 59 TYR H OH 1 ATOM 5205 N N . GLY C 3 61 ? 64.253 22.911 100.313 1.00 18.50 ? 60 GLY H N 1 ATOM 5206 C CA . GLY C 3 61 ? 63.404 21.876 99.803 1.00 22.81 ? 60 GLY H CA 1 ATOM 5207 C C . GLY C 3 61 ? 64.169 21.160 98.699 1.00 23.94 ? 60 GLY H C 1 ATOM 5208 O O . GLY C 3 61 ? 65.211 21.596 98.207 1.00 22.58 ? 60 GLY H O 1 ATOM 5209 N N . GLU C 3 62 ? 63.623 20.030 98.296 1.00 26.59 ? 61 GLU H N 1 ATOM 5210 C CA . GLU C 3 62 ? 64.212 19.265 97.219 1.00 28.66 ? 61 GLU H CA 1 ATOM 5211 C C . GLU C 3 62 ? 64.119 19.993 95.886 1.00 27.05 ? 61 GLU H C 1 ATOM 5212 O O . GLU C 3 62 ? 65.101 20.136 95.174 1.00 25.32 ? 61 GLU H O 1 ATOM 5213 C CB . GLU C 3 62 ? 63.495 17.914 97.175 1.00 32.67 ? 61 GLU H CB 1 ATOM 5214 C CG . GLU C 3 62 ? 64.336 16.724 96.732 1.00 37.89 ? 61 GLU H CG 1 ATOM 5215 C CD . GLU C 3 62 ? 65.612 16.639 97.553 1.00 42.31 ? 61 GLU H CD 1 ATOM 5216 O OE1 . GLU C 3 62 ? 65.548 16.222 98.717 1.00 45.93 ? 61 GLU H OE1 1 ATOM 5217 O OE2 . GLU C 3 62 ? 66.666 17.026 97.028 1.00 42.73 ? 61 GLU H OE2 1 ATOM 5218 N N . GLU C 3 63 ? 62.963 20.552 95.554 1.00 26.74 ? 62 GLU H N 1 ATOM 5219 C CA . GLU C 3 63 ? 62.758 21.268 94.304 1.00 27.45 ? 62 GLU H CA 1 ATOM 5220 C C . GLU C 3 63 ? 63.691 22.498 94.243 1.00 27.23 ? 62 GLU H C 1 ATOM 5221 O O . GLU C 3 63 ? 63.617 23.221 93.249 1.00 29.41 ? 62 GLU H O 1 ATOM 5222 C CB . GLU C 3 63 ? 61.240 21.648 94.260 1.00 29.59 ? 62 GLU H CB 1 ATOM 5223 C CG . GLU C 3 63 ? 60.448 21.637 92.927 1.00 33.62 ? 62 GLU H CG 1 ATOM 5224 C CD . GLU C 3 63 ? 60.215 22.943 92.104 1.00 35.93 ? 62 GLU H CD 1 ATOM 5225 O OE1 . GLU C 3 63 ? 61.161 23.530 91.564 1.00 37.24 ? 62 GLU H OE1 1 ATOM 5226 O OE2 . GLU C 3 63 ? 59.062 23.381 91.959 1.00 37.95 ? 62 GLU H OE2 1 ATOM 5227 N N . PHE C 3 64 ? 64.641 22.805 95.158 1.00 24.07 ? 63 PHE H N 1 ATOM 5228 C CA . PHE C 3 64 ? 65.309 24.110 95.160 1.00 21.00 ? 63 PHE H CA 1 ATOM 5229 C C . PHE C 3 64 ? 66.767 24.144 95.621 1.00 22.79 ? 63 PHE H C 1 ATOM 5230 O O . PHE C 3 64 ? 67.407 25.224 95.668 1.00 23.60 ? 63 PHE H O 1 ATOM 5231 C CB . PHE C 3 64 ? 64.560 25.097 96.074 1.00 18.63 ? 63 PHE H CB 1 ATOM 5232 C CG . PHE C 3 64 ? 63.086 25.324 95.784 1.00 17.10 ? 63 PHE H CG 1 ATOM 5233 C CD1 . PHE C 3 64 ? 62.681 25.900 94.594 1.00 16.53 ? 63 PHE H CD1 1 ATOM 5234 C CD2 . PHE C 3 64 ? 62.162 24.909 96.714 1.00 18.05 ? 63 PHE H CD2 1 ATOM 5235 C CE1 . PHE C 3 64 ? 61.350 26.053 94.325 1.00 16.63 ? 63 PHE H CE1 1 ATOM 5236 C CE2 . PHE C 3 64 ? 60.831 25.065 96.422 1.00 18.08 ? 63 PHE H CE2 1 ATOM 5237 C CZ . PHE C 3 64 ? 60.426 25.635 95.241 1.00 17.49 ? 63 PHE H CZ 1 ATOM 5238 N N . LYS C 3 65 ? 67.357 22.986 95.939 1.00 24.43 ? 64 LYS H N 1 ATOM 5239 C CA . LYS C 3 65 ? 68.685 22.971 96.568 1.00 24.68 ? 64 LYS H CA 1 ATOM 5240 C C . LYS C 3 65 ? 69.625 23.268 95.408 1.00 25.83 ? 64 LYS H C 1 ATOM 5241 O O . LYS C 3 65 ? 69.632 22.421 94.500 1.00 28.99 ? 64 LYS H O 1 ATOM 5242 C CB . LYS C 3 65 ? 68.893 21.578 97.167 1.00 23.47 ? 64 LYS H CB 1 ATOM 5243 C CG . LYS C 3 65 ? 70.098 21.365 98.070 1.00 22.04 ? 64 LYS H CG 1 ATOM 5244 C CD . LYS C 3 65 ? 70.035 19.924 98.571 1.00 21.28 ? 64 LYS H CD 1 ATOM 5245 C CE . LYS C 3 65 ? 71.086 19.606 99.625 1.00 21.01 ? 64 LYS H CE 1 ATOM 5246 N NZ . LYS C 3 65 ? 70.951 18.231 100.076 1.00 20.85 ? 64 LYS H NZ 1 ATOM 5247 N N . GLY C 3 66 ? 70.353 24.397 95.260 1.00 23.91 ? 65 GLY H N 1 ATOM 5248 C CA . GLY C 3 66 ? 71.208 24.501 94.053 1.00 21.92 ? 65 GLY H CA 1 ATOM 5249 C C . GLY C 3 66 ? 71.163 25.771 93.195 1.00 22.70 ? 65 GLY H C 1 ATOM 5250 O O . GLY C 3 66 ? 72.175 26.132 92.586 1.00 23.44 ? 65 GLY H O 1 ATOM 5251 N N . ARG C 3 67 ? 70.026 26.437 93.015 1.00 23.71 ? 66 ARG H N 1 ATOM 5252 C CA . ARG C 3 67 ? 70.025 27.748 92.357 1.00 21.93 ? 66 ARG H CA 1 ATOM 5253 C C . ARG C 3 67 ? 69.555 28.770 93.364 1.00 21.29 ? 66 ARG H C 1 ATOM 5254 O O . ARG C 3 67 ? 69.745 29.963 93.147 1.00 20.55 ? 66 ARG H O 1 ATOM 5255 C CB . ARG C 3 67 ? 69.071 27.837 91.158 1.00 23.39 ? 66 ARG H CB 1 ATOM 5256 C CG . ARG C 3 67 ? 69.581 27.253 89.853 1.00 24.02 ? 66 ARG H CG 1 ATOM 5257 C CD . ARG C 3 67 ? 68.833 27.806 88.650 1.00 23.58 ? 66 ARG H CD 1 ATOM 5258 N NE . ARG C 3 67 ? 67.520 27.227 88.433 1.00 23.40 ? 66 ARG H NE 1 ATOM 5259 C CZ . ARG C 3 67 ? 66.396 27.924 88.636 1.00 22.66 ? 66 ARG H CZ 1 ATOM 5260 N NH1 . ARG C 3 67 ? 66.437 29.181 89.076 1.00 23.97 ? 66 ARG H NH1 1 ATOM 5261 N NH2 . ARG C 3 67 ? 65.202 27.357 88.406 1.00 22.59 ? 66 ARG H NH2 1 ATOM 5262 N N . PHE C 3 68 ? 68.888 28.300 94.425 1.00 22.37 ? 67 PHE H N 1 ATOM 5263 C CA . PHE C 3 68 ? 68.380 29.174 95.454 1.00 22.65 ? 67 PHE H CA 1 ATOM 5264 C C . PHE C 3 68 ? 69.370 28.986 96.564 1.00 23.13 ? 67 PHE H C 1 ATOM 5265 O O . PHE C 3 68 ? 69.894 27.866 96.778 1.00 23.29 ? 67 PHE H O 1 ATOM 5266 C CB . PHE C 3 68 ? 67.045 28.752 95.971 1.00 23.50 ? 67 PHE H CB 1 ATOM 5267 C CG . PHE C 3 68 ? 66.101 28.684 94.813 1.00 23.59 ? 67 PHE H CG 1 ATOM 5268 C CD1 . PHE C 3 68 ? 66.001 27.528 94.098 1.00 23.29 ? 67 PHE H CD1 1 ATOM 5269 C CD2 . PHE C 3 68 ? 65.374 29.794 94.473 1.00 24.19 ? 67 PHE H CD2 1 ATOM 5270 C CE1 . PHE C 3 68 ? 65.157 27.499 93.023 1.00 24.88 ? 67 PHE H CE1 1 ATOM 5271 C CE2 . PHE C 3 68 ? 64.524 29.760 93.389 1.00 24.91 ? 67 PHE H CE2 1 ATOM 5272 C CZ . PHE C 3 68 ? 64.413 28.607 92.660 1.00 24.85 ? 67 PHE H CZ 1 ATOM 5273 N N . ALA C 3 69 ? 69.551 30.152 97.201 1.00 22.85 ? 68 ALA H N 1 ATOM 5274 C CA . ALA C 3 69 ? 70.461 30.352 98.313 1.00 21.01 ? 68 ALA H CA 1 ATOM 5275 C C . ALA C 3 69 ? 69.924 31.431 99.244 1.00 19.20 ? 68 ALA H C 1 ATOM 5276 O O . ALA C 3 69 ? 69.783 32.602 98.865 1.00 19.91 ? 68 ALA H O 1 ATOM 5277 C CB . ALA C 3 69 ? 71.832 30.820 97.842 1.00 21.79 ? 68 ALA H CB 1 ATOM 5278 N N . PHE C 3 70 ? 69.650 31.002 100.487 1.00 19.03 ? 69 PHE H N 1 ATOM 5279 C CA . PHE C 3 70 ? 69.126 31.841 101.553 1.00 18.31 ? 69 PHE H CA 1 ATOM 5280 C C . PHE C 3 70 ? 70.360 32.267 102.303 1.00 19.43 ? 69 PHE H C 1 ATOM 5281 O O . PHE C 3 70 ? 71.348 31.538 102.389 1.00 20.86 ? 69 PHE H O 1 ATOM 5282 C CB . PHE C 3 70 ? 68.264 31.118 102.583 1.00 17.44 ? 69 PHE H CB 1 ATOM 5283 C CG . PHE C 3 70 ? 67.135 30.274 102.045 1.00 16.79 ? 69 PHE H CG 1 ATOM 5284 C CD1 . PHE C 3 70 ? 66.582 30.538 100.813 1.00 17.77 ? 69 PHE H CD1 1 ATOM 5285 C CD2 . PHE C 3 70 ? 66.703 29.213 102.805 1.00 15.85 ? 69 PHE H CD2 1 ATOM 5286 C CE1 . PHE C 3 70 ? 65.596 29.742 100.325 1.00 18.00 ? 69 PHE H CE1 1 ATOM 5287 C CE2 . PHE C 3 70 ? 65.710 28.417 102.306 1.00 16.10 ? 69 PHE H CE2 1 ATOM 5288 C CZ . PHE C 3 70 ? 65.163 28.685 101.070 1.00 16.59 ? 69 PHE H CZ 1 ATOM 5289 N N . SER C 3 71 ? 70.266 33.452 102.861 1.00 22.53 ? 70 SER H N 1 ATOM 5290 C CA . SER C 3 71 ? 71.334 34.093 103.592 1.00 25.46 ? 70 SER H CA 1 ATOM 5291 C C . SER C 3 71 ? 70.632 35.177 104.384 1.00 26.79 ? 70 SER H C 1 ATOM 5292 O O . SER C 3 71 ? 69.404 35.255 104.301 1.00 29.23 ? 70 SER H O 1 ATOM 5293 C CB . SER C 3 71 ? 72.335 34.675 102.578 1.00 26.74 ? 70 SER H CB 1 ATOM 5294 O OG . SER C 3 71 ? 71.762 35.385 101.469 1.00 28.14 ? 70 SER H OG 1 ATOM 5295 N N . LEU C 3 72 ? 71.305 36.024 105.163 1.00 25.41 ? 71 LEU H N 1 ATOM 5296 C CA . LEU C 3 72 ? 70.645 37.080 105.914 1.00 26.94 ? 71 LEU H CA 1 ATOM 5297 C C . LEU C 3 72 ? 71.599 38.150 106.375 1.00 27.93 ? 71 LEU H C 1 ATOM 5298 O O . LEU C 3 72 ? 72.766 37.816 106.473 1.00 30.76 ? 71 LEU H O 1 ATOM 5299 C CB . LEU C 3 72 ? 69.936 36.478 107.134 1.00 27.96 ? 71 LEU H CB 1 ATOM 5300 C CG . LEU C 3 72 ? 70.364 35.114 107.682 1.00 27.88 ? 71 LEU H CG 1 ATOM 5301 C CD1 . LEU C 3 72 ? 71.708 35.220 108.392 1.00 29.75 ? 71 LEU H CD1 1 ATOM 5302 C CD2 . LEU C 3 72 ? 69.278 34.606 108.581 1.00 27.20 ? 71 LEU H CD2 1 ATOM 5303 N N . GLU C 3 73 ? 71.205 39.408 106.604 1.00 30.17 ? 72 GLU H N 1 ATOM 5304 C CA . GLU C 3 73 ? 72.051 40.441 107.181 1.00 33.93 ? 72 GLU H CA 1 ATOM 5305 C C . GLU C 3 73 ? 71.392 40.682 108.515 1.00 35.38 ? 72 GLU H C 1 ATOM 5306 O O . GLU C 3 73 ? 70.591 41.596 108.722 1.00 36.19 ? 72 GLU H O 1 ATOM 5307 C CB . GLU C 3 73 ? 72.025 41.760 106.430 1.00 36.00 ? 72 GLU H CB 1 ATOM 5308 C CG . GLU C 3 73 ? 72.614 41.697 105.037 1.00 39.54 ? 72 GLU H CG 1 ATOM 5309 C CD . GLU C 3 73 ? 71.681 42.103 103.888 1.00 42.39 ? 72 GLU H CD 1 ATOM 5310 O OE1 . GLU C 3 73 ? 70.557 42.572 104.118 1.00 43.61 ? 72 GLU H OE1 1 ATOM 5311 O OE2 . GLU C 3 73 ? 72.084 41.955 102.733 1.00 44.99 ? 72 GLU H OE2 1 ATOM 5312 N N . THR C 3 74 ? 71.735 39.823 109.448 1.00 36.30 ? 73 THR H N 1 ATOM 5313 C CA . THR C 3 74 ? 71.218 39.822 110.810 1.00 37.79 ? 73 THR H CA 1 ATOM 5314 C C . THR C 3 74 ? 71.260 41.171 111.472 1.00 38.23 ? 73 THR H C 1 ATOM 5315 O O . THR C 3 74 ? 70.348 41.509 112.204 1.00 38.83 ? 73 THR H O 1 ATOM 5316 C CB . THR C 3 74 ? 72.013 38.800 111.654 1.00 37.73 ? 73 THR H CB 1 ATOM 5317 O OG1 . THR C 3 74 ? 73.287 38.645 111.000 1.00 39.57 ? 73 THR H OG1 1 ATOM 5318 C CG2 . THR C 3 74 ? 71.282 37.458 111.823 1.00 37.94 ? 73 THR H CG2 1 ATOM 5319 N N . SER C 3 75 ? 72.296 41.939 111.157 1.00 38.34 ? 74 SER H N 1 ATOM 5320 C CA . SER C 3 75 ? 72.535 43.308 111.602 1.00 38.01 ? 74 SER H CA 1 ATOM 5321 C C . SER C 3 75 ? 71.405 44.304 111.324 1.00 36.19 ? 74 SER H C 1 ATOM 5322 O O . SER C 3 75 ? 71.246 45.358 111.950 1.00 35.10 ? 74 SER H O 1 ATOM 5323 C CB . SER C 3 75 ? 73.820 43.800 110.924 1.00 39.45 ? 74 SER H CB 1 ATOM 5324 O OG . SER C 3 75 ? 74.840 42.791 110.898 1.00 38.53 ? 74 SER H OG 1 ATOM 5325 N N . ALA C 3 76 ? 70.644 43.949 110.303 1.00 34.05 ? 75 ALA H N 1 ATOM 5326 C CA . ALA C 3 76 ? 69.520 44.729 109.844 1.00 31.92 ? 75 ALA H CA 1 ATOM 5327 C C . ALA C 3 76 ? 68.281 43.843 109.899 1.00 30.58 ? 75 ALA H C 1 ATOM 5328 O O . ALA C 3 76 ? 67.220 44.180 109.349 1.00 30.72 ? 75 ALA H O 1 ATOM 5329 C CB . ALA C 3 76 ? 69.812 45.141 108.418 1.00 32.36 ? 75 ALA H CB 1 ATOM 5330 N N . SER C 3 77 ? 68.433 42.682 110.566 1.00 26.30 ? 76 SER H N 1 ATOM 5331 C CA . SER C 3 77 ? 67.404 41.660 110.631 1.00 22.76 ? 76 SER H CA 1 ATOM 5332 C C . SER C 3 77 ? 66.872 41.309 109.212 1.00 20.76 ? 76 SER H C 1 ATOM 5333 O O . SER C 3 77 ? 65.713 40.919 109.046 1.00 20.57 ? 76 SER H O 1 ATOM 5334 C CB . SER C 3 77 ? 66.296 42.211 111.549 1.00 23.95 ? 76 SER H CB 1 ATOM 5335 O OG . SER C 3 77 ? 66.734 43.252 112.444 1.00 27.00 ? 76 SER H OG 1 ATOM 5336 N N . THR C 3 78 ? 67.623 41.449 108.102 1.00 18.59 ? 77 THR H N 1 ATOM 5337 C CA . THR C 3 78 ? 67.068 41.167 106.782 1.00 19.83 ? 77 THR H CA 1 ATOM 5338 C C . THR C 3 78 ? 67.402 39.733 106.377 1.00 18.90 ? 77 THR H C 1 ATOM 5339 O O . THR C 3 78 ? 68.524 39.313 106.656 1.00 20.40 ? 77 THR H O 1 ATOM 5340 C CB . THR C 3 78 ? 67.663 42.204 105.798 1.00 21.09 ? 77 THR H CB 1 ATOM 5341 O OG1 . THR C 3 78 ? 67.534 43.497 106.419 1.00 23.26 ? 77 THR H OG1 1 ATOM 5342 C CG2 . THR C 3 78 ? 66.972 42.168 104.433 1.00 22.78 ? 77 THR H CG2 1 ATOM 5343 N N . ALA C 3 79 ? 66.455 38.943 105.838 1.00 18.60 ? 78 ALA H N 1 ATOM 5344 C CA . ALA C 3 79 ? 66.739 37.611 105.334 1.00 19.91 ? 78 ALA H CA 1 ATOM 5345 C C . ALA C 3 79 ? 66.621 37.835 103.862 1.00 22.30 ? 78 ALA H C 1 ATOM 5346 O O . ALA C 3 79 ? 65.741 38.581 103.428 1.00 22.88 ? 78 ALA H O 1 ATOM 5347 C CB . ALA C 3 79 ? 65.699 36.608 105.692 1.00 18.78 ? 78 ALA H CB 1 ATOM 5348 N N . ASN C 3 80 ? 67.485 37.219 103.079 1.00 22.03 ? 79 ASN H N 1 ATOM 5349 C CA . ASN C 3 80 ? 67.557 37.494 101.657 1.00 20.73 ? 79 ASN H CA 1 ATOM 5350 C C . ASN C 3 80 ? 67.537 36.174 100.941 1.00 21.29 ? 79 ASN H C 1 ATOM 5351 O O . ASN C 3 80 ? 68.100 35.207 101.467 1.00 22.14 ? 79 ASN H O 1 ATOM 5352 C CB . ASN C 3 80 ? 68.848 38.149 101.235 1.00 18.55 ? 79 ASN H CB 1 ATOM 5353 C CG . ASN C 3 80 ? 69.226 39.404 101.972 1.00 18.73 ? 79 ASN H CG 1 ATOM 5354 O OD1 . ASN C 3 80 ? 68.874 39.610 103.112 1.00 21.42 ? 79 ASN H OD1 1 ATOM 5355 N ND2 . ASN C 3 80 ? 69.969 40.342 101.429 1.00 17.15 ? 79 ASN H ND2 1 ATOM 5356 N N . LEU C 3 81 ? 66.868 36.052 99.810 1.00 19.85 ? 80 LEU H N 1 ATOM 5357 C CA . LEU C 3 81 ? 66.920 34.852 99.014 1.00 19.23 ? 80 LEU H CA 1 ATOM 5358 C C . LEU C 3 81 ? 67.453 35.279 97.687 1.00 20.93 ? 80 LEU H C 1 ATOM 5359 O O . LEU C 3 81 ? 67.011 36.283 97.133 1.00 20.77 ? 80 LEU H O 1 ATOM 5360 C CB . LEU C 3 81 ? 65.536 34.261 98.837 1.00 18.50 ? 80 LEU H CB 1 ATOM 5361 C CG . LEU C 3 81 ? 65.042 33.659 97.532 1.00 18.68 ? 80 LEU H CG 1 ATOM 5362 C CD1 . LEU C 3 81 ? 64.833 32.163 97.705 1.00 20.11 ? 80 LEU H CD1 1 ATOM 5363 C CD2 . LEU C 3 81 ? 63.759 34.362 97.114 1.00 20.06 ? 80 LEU H CD2 1 ATOM 5364 N N . GLN C 3 82 ? 68.396 34.506 97.195 1.00 22.95 ? 81 GLN H N 1 ATOM 5365 C CA . GLN C 3 82 ? 68.940 34.742 95.880 1.00 24.82 ? 81 GLN H CA 1 ATOM 5366 C C . GLN C 3 82 ? 68.751 33.559 94.910 1.00 23.92 ? 81 GLN H C 1 ATOM 5367 O O . GLN C 3 82 ? 68.884 32.383 95.290 1.00 21.86 ? 81 GLN H O 1 ATOM 5368 C CB . GLN C 3 82 ? 70.398 35.091 96.073 1.00 27.56 ? 81 GLN H CB 1 ATOM 5369 C CG . GLN C 3 82 ? 71.078 35.378 94.758 1.00 30.31 ? 81 GLN H CG 1 ATOM 5370 C CD . GLN C 3 82 ? 72.497 35.881 94.908 1.00 32.76 ? 81 GLN H CD 1 ATOM 5371 O OE1 . GLN C 3 82 ? 72.710 37.023 95.330 1.00 34.98 ? 81 GLN H OE1 1 ATOM 5372 N NE2 . GLN C 3 82 ? 73.488 35.073 94.519 1.00 32.99 ? 81 GLN H NE2 1 ATOM 5373 N N . ILE C 3 83 ? 68.415 33.850 93.645 1.00 25.13 ? 82 ILE H N 1 ATOM 5374 C CA . ILE C 3 83 ? 68.197 32.823 92.638 1.00 25.98 ? 82 ILE H CA 1 ATOM 5375 C C . ILE C 3 83 ? 69.174 33.175 91.555 1.00 28.19 ? 82 ILE H C 1 ATOM 5376 O O . ILE C 3 83 ? 69.230 34.324 91.096 1.00 27.01 ? 82 ILE H O 1 ATOM 5377 C CB . ILE C 3 83 ? 66.784 32.874 92.092 1.00 26.85 ? 82 ILE H CB 1 ATOM 5378 C CG1 . ILE C 3 83 ? 65.702 32.924 93.166 1.00 27.07 ? 82 ILE H CG1 1 ATOM 5379 C CG2 . ILE C 3 83 ? 66.623 31.596 91.333 1.00 25.38 ? 82 ILE H CG2 1 ATOM 5380 C CD1 . ILE C 3 83 ? 64.589 34.002 93.064 1.00 26.88 ? 82 ILE H CD1 1 ATOM 5381 N N . ASN C 3 84 A 70.032 32.186 91.326 1.00 30.56 ? 82 ASN H N 1 ATOM 5382 C CA . ASN C 3 84 A 71.085 32.235 90.313 1.00 32.50 ? 82 ASN H CA 1 ATOM 5383 C C . ASN C 3 84 A 70.609 31.607 88.999 1.00 32.82 ? 82 ASN H C 1 ATOM 5384 O O . ASN C 3 84 A 69.745 30.725 89.076 1.00 33.54 ? 82 ASN H O 1 ATOM 5385 C CB . ASN C 3 84 A 72.334 31.488 90.819 1.00 32.84 ? 82 ASN H CB 1 ATOM 5386 C CG . ASN C 3 84 A 73.173 32.359 91.757 1.00 33.16 ? 82 ASN H CG 1 ATOM 5387 O OD1 . ASN C 3 84 A 72.951 32.448 92.977 1.00 33.52 ? 82 ASN H OD1 1 ATOM 5388 N ND2 . ASN C 3 84 A 74.154 33.113 91.262 1.00 32.51 ? 82 ASN H ND2 1 ATOM 5389 N N . ASN C 3 85 B 71.146 31.972 87.808 1.00 31.96 ? 82 ASN H N 1 ATOM 5390 C CA . ASN C 3 85 B 70.692 31.481 86.498 1.00 31.71 ? 82 ASN H CA 1 ATOM 5391 C C . ASN C 3 85 B 69.160 31.418 86.357 1.00 30.93 ? 82 ASN H C 1 ATOM 5392 O O . ASN C 3 85 B 68.475 30.376 86.418 1.00 28.80 ? 82 ASN H O 1 ATOM 5393 C CB . ASN C 3 85 B 71.290 30.089 86.208 1.00 33.47 ? 82 ASN H CB 1 ATOM 5394 C CG . ASN C 3 85 B 70.593 29.449 84.996 1.00 36.62 ? 82 ASN H CG 1 ATOM 5395 O OD1 . ASN C 3 85 B 70.581 29.981 83.881 1.00 38.17 ? 82 ASN H OD1 1 ATOM 5396 N ND2 . ASN C 3 85 B 69.849 28.363 85.190 1.00 38.98 ? 82 ASN H ND2 1 ATOM 5397 N N . LEU C 3 86 C 68.566 32.588 86.198 1.00 31.28 ? 82 LEU H N 1 ATOM 5398 C CA . LEU C 3 86 C 67.121 32.604 86.216 1.00 31.14 ? 82 LEU H CA 1 ATOM 5399 C C . LEU C 3 86 C 66.556 31.930 85.000 1.00 31.15 ? 82 LEU H C 1 ATOM 5400 O O . LEU C 3 86 C 66.828 32.321 83.869 1.00 32.23 ? 82 LEU H O 1 ATOM 5401 C CB . LEU C 3 86 C 66.620 34.049 86.328 1.00 30.51 ? 82 LEU H CB 1 ATOM 5402 C CG . LEU C 3 86 C 66.679 34.647 87.760 1.00 29.66 ? 82 LEU H CG 1 ATOM 5403 C CD1 . LEU C 3 86 C 66.829 36.162 87.681 1.00 26.89 ? 82 LEU H CD1 1 ATOM 5404 C CD2 . LEU C 3 86 C 65.447 34.187 88.561 1.00 29.60 ? 82 LEU H CD2 1 ATOM 5405 N N . LYS C 3 87 ? 65.929 30.803 85.274 1.00 31.06 ? 83 LYS H N 1 ATOM 5406 C CA . LYS C 3 87 ? 65.127 30.122 84.286 1.00 32.23 ? 83 LYS H CA 1 ATOM 5407 C C . LYS C 3 87 ? 63.784 30.813 84.319 1.00 32.75 ? 83 LYS H C 1 ATOM 5408 O O . LYS C 3 87 ? 63.276 31.097 85.394 1.00 30.75 ? 83 LYS H O 1 ATOM 5409 C CB . LYS C 3 87 ? 64.992 28.706 84.680 1.00 33.26 ? 83 LYS H CB 1 ATOM 5410 C CG . LYS C 3 87 ? 66.359 28.139 84.390 1.00 35.25 ? 83 LYS H CG 1 ATOM 5411 C CD . LYS C 3 87 ? 66.787 26.975 85.281 1.00 37.78 ? 83 LYS H CD 1 ATOM 5412 C CE . LYS C 3 87 ? 66.104 25.615 85.047 1.00 37.60 ? 83 LYS H CE 1 ATOM 5413 N NZ . LYS C 3 87 ? 64.646 25.651 85.122 1.00 39.31 ? 83 LYS H NZ 1 ATOM 5414 N N . ASN C 3 88 ? 63.152 31.147 83.200 1.00 36.39 ? 84 ASN H N 1 ATOM 5415 C CA . ASN C 3 88 ? 61.833 31.793 83.162 1.00 39.88 ? 84 ASN H CA 1 ATOM 5416 C C . ASN C 3 88 ? 60.766 31.072 83.977 1.00 40.01 ? 84 ASN H C 1 ATOM 5417 O O . ASN C 3 88 ? 59.862 31.715 84.501 1.00 42.32 ? 84 ASN H O 1 ATOM 5418 C CB . ASN C 3 88 ? 61.321 31.933 81.699 1.00 42.12 ? 84 ASN H CB 1 ATOM 5419 C CG . ASN C 3 88 ? 60.969 30.631 80.960 1.00 43.76 ? 84 ASN H CG 1 ATOM 5420 O OD1 . ASN C 3 88 ? 61.182 29.495 81.428 1.00 45.49 ? 84 ASN H OD1 1 ATOM 5421 N ND2 . ASN C 3 88 ? 60.431 30.762 79.750 1.00 43.77 ? 84 ASN H ND2 1 ATOM 5422 N N . GLU C 3 89 ? 60.882 29.754 84.157 1.00 37.93 ? 85 GLU H N 1 ATOM 5423 C CA . GLU C 3 89 ? 59.977 29.052 85.032 1.00 34.54 ? 85 GLU H CA 1 ATOM 5424 C C . GLU C 3 89 ? 60.098 29.503 86.502 1.00 33.86 ? 85 GLU H C 1 ATOM 5425 O O . GLU C 3 89 ? 59.443 28.930 87.372 1.00 34.13 ? 85 GLU H O 1 ATOM 5426 C CB . GLU C 3 89 ? 60.210 27.547 84.913 1.00 34.45 ? 85 GLU H CB 1 ATOM 5427 C CG . GLU C 3 89 ? 61.590 27.014 85.247 1.00 33.85 ? 85 GLU H CG 1 ATOM 5428 C CD . GLU C 3 89 ? 61.602 25.501 85.414 1.00 33.65 ? 85 GLU H CD 1 ATOM 5429 O OE1 . GLU C 3 89 ? 61.522 24.786 84.417 1.00 33.52 ? 85 GLU H OE1 1 ATOM 5430 O OE2 . GLU C 3 89 ? 61.705 25.040 86.551 1.00 33.63 ? 85 GLU H OE2 1 ATOM 5431 N N . ASP C 3 90 ? 60.879 30.534 86.865 1.00 32.89 ? 86 ASP H N 1 ATOM 5432 C CA . ASP C 3 90 ? 60.912 31.107 88.213 1.00 30.47 ? 86 ASP H CA 1 ATOM 5433 C C . ASP C 3 90 ? 59.984 32.326 88.285 1.00 30.99 ? 86 ASP H C 1 ATOM 5434 O O . ASP C 3 90 ? 60.115 33.200 89.149 1.00 31.61 ? 86 ASP H O 1 ATOM 5435 C CB . ASP C 3 90 ? 62.321 31.569 88.599 1.00 28.93 ? 86 ASP H CB 1 ATOM 5436 C CG . ASP C 3 90 ? 63.423 30.520 88.501 1.00 27.85 ? 86 ASP H CG 1 ATOM 5437 O OD1 . ASP C 3 90 ? 63.137 29.322 88.693 1.00 26.08 ? 86 ASP H OD1 1 ATOM 5438 O OD2 . ASP C 3 90 ? 64.555 30.949 88.227 1.00 27.04 ? 86 ASP H OD2 1 ATOM 5439 N N . LYS C 3 91 ? 59.064 32.454 87.332 1.00 30.94 ? 87 LYS H N 1 ATOM 5440 C CA . LYS C 3 91 ? 58.064 33.497 87.349 1.00 29.86 ? 87 LYS H CA 1 ATOM 5441 C C . LYS C 3 91 ? 57.025 33.330 88.465 1.00 27.18 ? 87 LYS H C 1 ATOM 5442 O O . LYS C 3 91 ? 56.063 32.540 88.373 1.00 26.47 ? 87 LYS H O 1 ATOM 5443 C CB . LYS C 3 91 ? 57.445 33.477 85.996 1.00 31.11 ? 87 LYS H CB 1 ATOM 5444 C CG . LYS C 3 91 ? 58.203 34.553 85.274 1.00 33.87 ? 87 LYS H CG 1 ATOM 5445 C CD . LYS C 3 91 ? 57.251 35.377 84.416 1.00 37.66 ? 87 LYS H CD 1 ATOM 5446 C CE . LYS C 3 91 ? 55.918 35.762 85.122 1.00 38.63 ? 87 LYS H CE 1 ATOM 5447 N NZ . LYS C 3 91 ? 56.067 36.250 86.495 1.00 39.55 ? 87 LYS H NZ 1 ATOM 5448 N N . ALA C 3 92 ? 57.174 34.066 89.552 1.00 23.47 ? 88 ALA H N 1 ATOM 5449 C CA . ALA C 3 92 ? 56.309 33.819 90.683 1.00 21.25 ? 88 ALA H CA 1 ATOM 5450 C C . ALA C 3 92 ? 56.416 34.980 91.639 1.00 20.86 ? 88 ALA H C 1 ATOM 5451 O O . ALA C 3 92 ? 57.012 36.023 91.314 1.00 21.52 ? 88 ALA H O 1 ATOM 5452 C CB . ALA C 3 92 ? 56.751 32.536 91.365 1.00 18.83 ? 88 ALA H CB 1 ATOM 5453 N N . THR C 3 93 ? 55.850 34.782 92.819 1.00 19.12 ? 89 THR H N 1 ATOM 5454 C CA . THR C 3 93 ? 55.913 35.784 93.852 1.00 17.80 ? 89 THR H CA 1 ATOM 5455 C C . THR C 3 93 ? 56.403 35.027 95.048 1.00 18.38 ? 89 THR H C 1 ATOM 5456 O O . THR C 3 93 ? 55.685 34.193 95.594 1.00 20.03 ? 89 THR H O 1 ATOM 5457 C CB . THR C 3 93 ? 54.557 36.332 94.157 1.00 15.71 ? 89 THR H CB 1 ATOM 5458 O OG1 . THR C 3 93 ? 53.769 36.325 92.944 1.00 16.16 ? 89 THR H OG1 1 ATOM 5459 C CG2 . THR C 3 93 ? 54.719 37.711 94.748 1.00 15.67 ? 89 THR H CG2 1 ATOM 5460 N N . PHE C 3 94 ? 57.634 35.274 95.454 1.00 17.13 ? 90 PHE H N 1 ATOM 5461 C CA . PHE C 3 94 ? 58.241 34.555 96.573 1.00 15.34 ? 90 PHE H CA 1 ATOM 5462 C C . PHE C 3 94 ? 57.934 35.311 97.855 1.00 14.73 ? 90 PHE H C 1 ATOM 5463 O O . PHE C 3 94 ? 58.001 36.545 97.890 1.00 14.08 ? 90 PHE H O 1 ATOM 5464 C CB . PHE C 3 94 ? 59.746 34.461 96.316 1.00 16.92 ? 90 PHE H CB 1 ATOM 5465 C CG . PHE C 3 94 ? 59.988 33.800 94.963 1.00 16.33 ? 90 PHE H CG 1 ATOM 5466 C CD1 . PHE C 3 94 ? 60.080 32.420 94.913 1.00 15.95 ? 90 PHE H CD1 1 ATOM 5467 C CD2 . PHE C 3 94 ? 60.067 34.566 93.810 1.00 16.60 ? 90 PHE H CD2 1 ATOM 5468 C CE1 . PHE C 3 94 ? 60.247 31.814 93.691 1.00 14.33 ? 90 PHE H CE1 1 ATOM 5469 C CE2 . PHE C 3 94 ? 60.235 33.929 92.609 1.00 16.23 ? 90 PHE H CE2 1 ATOM 5470 C CZ . PHE C 3 94 ? 60.325 32.564 92.539 1.00 14.19 ? 90 PHE H CZ 1 ATOM 5471 N N . PHE C 3 95 ? 57.517 34.598 98.890 1.00 14.03 ? 91 PHE H N 1 ATOM 5472 C CA . PHE C 3 95 ? 57.136 35.199 100.154 1.00 11.16 ? 91 PHE H CA 1 ATOM 5473 C C . PHE C 3 95 ? 58.144 34.921 101.213 1.00 10.72 ? 91 PHE H C 1 ATOM 5474 O O . PHE C 3 95 ? 58.735 33.857 101.188 1.00 13.93 ? 91 PHE H O 1 ATOM 5475 C CB . PHE C 3 95 ? 55.868 34.656 100.713 1.00 8.11 ? 91 PHE H CB 1 ATOM 5476 C CG . PHE C 3 95 ? 54.655 35.015 99.915 1.00 6.11 ? 91 PHE H CG 1 ATOM 5477 C CD1 . PHE C 3 95 ? 54.052 36.223 100.151 1.00 8.23 ? 91 PHE H CD1 1 ATOM 5478 C CD2 . PHE C 3 95 ? 54.196 34.145 98.949 1.00 6.07 ? 91 PHE H CD2 1 ATOM 5479 C CE1 . PHE C 3 95 ? 52.961 36.578 99.403 1.00 9.00 ? 91 PHE H CE1 1 ATOM 5480 C CE2 . PHE C 3 95 ? 53.104 34.514 98.202 1.00 5.91 ? 91 PHE H CE2 1 ATOM 5481 C CZ . PHE C 3 95 ? 52.488 35.729 98.430 1.00 7.65 ? 91 PHE H CZ 1 ATOM 5482 N N . CYS C 3 96 ? 58.406 35.811 102.131 1.00 7.55 ? 92 CYS H N 1 ATOM 5483 C CA . CYS C 3 96 ? 59.172 35.425 103.286 1.00 5.59 ? 92 CYS H CA 1 ATOM 5484 C C . CYS C 3 96 ? 58.076 35.310 104.299 1.00 4.74 ? 92 CYS H C 1 ATOM 5485 O O . CYS C 3 96 ? 57.140 36.115 104.173 1.00 3.98 ? 92 CYS H O 1 ATOM 5486 C CB . CYS C 3 96 ? 60.137 36.494 103.745 1.00 7.36 ? 92 CYS H CB 1 ATOM 5487 S SG . CYS C 3 96 ? 59.457 38.149 103.998 1.00 9.08 ? 92 CYS H SG 1 ATOM 5488 N N . ALA C 3 97 ? 58.111 34.387 105.257 1.00 4.97 ? 93 ALA H N 1 ATOM 5489 C CA . ALA C 3 97 ? 57.090 34.248 106.306 1.00 5.69 ? 93 ALA H CA 1 ATOM 5490 C C . ALA C 3 97 ? 57.808 33.694 107.545 1.00 6.19 ? 93 ALA H C 1 ATOM 5491 O O . ALA C 3 97 ? 58.767 32.906 107.419 1.00 5.11 ? 93 ALA H O 1 ATOM 5492 C CB . ALA C 3 97 ? 55.974 33.266 105.867 1.00 6.23 ? 93 ALA H CB 1 ATOM 5493 N N . ARG C 3 98 ? 57.417 34.131 108.736 1.00 7.55 ? 94 ARG H N 1 ATOM 5494 C CA . ARG C 3 98 ? 58.127 33.733 109.933 1.00 5.16 ? 94 ARG H CA 1 ATOM 5495 C C . ARG C 3 98 ? 57.885 32.292 110.387 1.00 4.65 ? 94 ARG H C 1 ATOM 5496 O O . ARG C 3 98 ? 56.753 31.805 110.492 1.00 3.24 ? 94 ARG H O 1 ATOM 5497 C CB . ARG C 3 98 ? 57.744 34.749 110.985 1.00 4.47 ? 94 ARG H CB 1 ATOM 5498 C CG . ARG C 3 98 ? 58.283 34.687 112.385 1.00 3.29 ? 94 ARG H CG 1 ATOM 5499 C CD . ARG C 3 98 ? 57.532 35.847 112.942 1.00 3.61 ? 94 ARG H CD 1 ATOM 5500 N NE . ARG C 3 98 ? 57.786 36.004 114.339 1.00 3.49 ? 94 ARG H NE 1 ATOM 5501 C CZ . ARG C 3 98 ? 56.857 35.802 115.263 1.00 2.06 ? 94 ARG H CZ 1 ATOM 5502 N NH1 . ARG C 3 98 ? 55.676 35.299 114.982 1.00 4.16 ? 94 ARG H NH1 1 ATOM 5503 N NH2 . ARG C 3 98 ? 57.135 36.019 116.545 1.00 2.12 ? 94 ARG H NH2 1 ATOM 5504 N N . GLY C 3 99 ? 58.966 31.556 110.614 1.00 6.49 ? 95 GLY H N 1 ATOM 5505 C CA . GLY C 3 99 ? 58.849 30.226 111.153 1.00 7.43 ? 95 GLY H CA 1 ATOM 5506 C C . GLY C 3 99 ? 58.505 30.337 112.631 1.00 8.89 ? 95 GLY H C 1 ATOM 5507 O O . GLY C 3 99 ? 59.399 30.574 113.438 1.00 10.83 ? 95 GLY H O 1 ATOM 5508 N N . GLU C 3 100 ? 57.236 30.212 113.028 1.00 9.03 ? 96 GLU H N 1 ATOM 5509 C CA . GLU C 3 100 ? 56.801 30.227 114.426 1.00 8.23 ? 96 GLU H CA 1 ATOM 5510 C C . GLU C 3 100 ? 57.619 29.306 115.319 1.00 8.81 ? 96 GLU H C 1 ATOM 5511 O O . GLU C 3 100 ? 57.920 29.596 116.468 1.00 11.20 ? 96 GLU H O 1 ATOM 5512 C CB . GLU C 3 100 ? 55.324 29.814 114.492 1.00 8.00 ? 96 GLU H CB 1 ATOM 5513 C CG . GLU C 3 100 ? 54.573 29.952 115.826 1.00 10.18 ? 96 GLU H CG 1 ATOM 5514 C CD . GLU C 3 100 ? 54.892 28.930 116.934 1.00 10.32 ? 96 GLU H CD 1 ATOM 5515 O OE1 . GLU C 3 100 ? 54.907 27.730 116.614 1.00 8.02 ? 96 GLU H OE1 1 ATOM 5516 O OE2 . GLU C 3 100 ? 55.145 29.324 118.090 1.00 14.94 ? 96 GLU H OE2 1 ATOM 5517 N N . ASP C 3 101 ? 57.927 28.133 114.825 1.00 8.80 ? 97 ASP H N 1 ATOM 5518 C CA . ASP C 3 101 ? 58.677 27.137 115.552 1.00 8.65 ? 97 ASP H CA 1 ATOM 5519 C C . ASP C 3 101 ? 59.958 26.849 114.775 1.00 8.19 ? 97 ASP H C 1 ATOM 5520 O O . ASP C 3 101 ? 60.151 27.362 113.667 1.00 10.27 ? 97 ASP H O 1 ATOM 5521 C CB . ASP C 3 101 ? 57.846 25.874 115.658 1.00 8.65 ? 97 ASP H CB 1 ATOM 5522 C CG . ASP C 3 101 ? 57.402 25.336 114.311 1.00 8.50 ? 97 ASP H CG 1 ATOM 5523 O OD1 . ASP C 3 101 ? 56.646 26.016 113.614 1.00 7.20 ? 97 ASP H OD1 1 ATOM 5524 O OD2 . ASP C 3 101 ? 57.851 24.248 113.963 1.00 12.89 ? 97 ASP H OD2 1 ATOM 5525 N N . ASN C 3 102 ? 60.846 26.034 115.348 1.00 7.11 ? 98 ASN H N 1 ATOM 5526 C CA . ASN C 3 102 ? 62.026 25.489 114.673 1.00 6.76 ? 98 ASN H CA 1 ATOM 5527 C C . ASN C 3 102 ? 61.604 24.674 113.461 1.00 10.05 ? 98 ASN H C 1 ATOM 5528 O O . ASN C 3 102 ? 60.723 23.829 113.577 1.00 10.31 ? 98 ASN H O 1 ATOM 5529 C CB . ASN C 3 102 ? 62.761 24.582 115.627 1.00 6.08 ? 98 ASN H CB 1 ATOM 5530 C CG . ASN C 3 102 ? 64.086 24.041 115.131 1.00 3.19 ? 98 ASN H CG 1 ATOM 5531 O OD1 . ASN C 3 102 ? 64.853 24.661 114.380 1.00 4.96 ? 98 ASN H OD1 1 ATOM 5532 N ND2 . ASN C 3 102 ? 64.348 22.831 115.580 1.00 2.13 ? 98 ASN H ND2 1 ATOM 5533 N N . PHE C 3 103 ? 62.211 24.913 112.315 1.00 12.32 ? 99 PHE H N 1 ATOM 5534 C CA . PHE C 3 103 ? 61.931 24.308 111.016 1.00 16.74 ? 99 PHE H CA 1 ATOM 5535 C C . PHE C 3 103 ? 60.773 24.919 110.265 1.00 16.15 ? 99 PHE H C 1 ATOM 5536 O O . PHE C 3 103 ? 60.603 24.585 109.098 1.00 22.11 ? 99 PHE H O 1 ATOM 5537 C CB . PHE C 3 103 ? 61.624 22.782 111.051 1.00 20.39 ? 99 PHE H CB 1 ATOM 5538 C CG . PHE C 3 103 ? 62.873 21.973 110.868 1.00 24.74 ? 99 PHE H CG 1 ATOM 5539 C CD1 . PHE C 3 103 ? 63.699 21.730 111.931 1.00 25.91 ? 99 PHE H CD1 1 ATOM 5540 C CD2 . PHE C 3 103 ? 63.184 21.554 109.606 1.00 28.79 ? 99 PHE H CD2 1 ATOM 5541 C CE1 . PHE C 3 103 ? 64.869 21.062 111.733 1.00 28.01 ? 99 PHE H CE1 1 ATOM 5542 C CE2 . PHE C 3 103 ? 64.354 20.886 109.403 1.00 31.65 ? 99 PHE H CE2 1 ATOM 5543 C CZ . PHE C 3 103 ? 65.186 20.647 110.466 1.00 30.46 ? 99 PHE H CZ 1 ATOM 5544 N N . GLY C 3 104 ? 59.932 25.773 110.843 1.00 13.46 ? 100 GLY H N 1 ATOM 5545 C CA . GLY C 3 104 ? 58.863 26.413 110.109 1.00 10.80 ? 100 GLY H CA 1 ATOM 5546 C C . GLY C 3 104 ? 57.603 25.606 109.901 1.00 10.49 ? 100 GLY H C 1 ATOM 5547 O O . GLY C 3 104 ? 56.984 25.730 108.865 1.00 15.82 ? 100 GLY H O 1 ATOM 5548 N N . SER C 3 105 A 57.073 24.828 110.824 1.00 10.19 ? 100 SER H N 1 ATOM 5549 C CA . SER C 3 105 A 55.825 24.129 110.562 1.00 10.76 ? 100 SER H CA 1 ATOM 5550 C C . SER C 3 105 A 54.584 25.015 110.555 1.00 12.15 ? 100 SER H C 1 ATOM 5551 O O . SER C 3 105 A 53.473 24.593 110.277 1.00 14.40 ? 100 SER H O 1 ATOM 5552 C CB . SER C 3 105 A 55.651 22.985 111.600 1.00 12.51 ? 100 SER H CB 1 ATOM 5553 O OG . SER C 3 105 A 55.469 23.289 112.973 1.00 14.19 ? 100 SER H OG 1 ATOM 5554 N N . LEU C 3 106 B 54.715 26.282 110.837 1.00 13.42 ? 100 LEU H N 1 ATOM 5555 C CA . LEU C 3 106 B 53.606 27.173 110.996 1.00 12.03 ? 100 LEU H CA 1 ATOM 5556 C C . LEU C 3 106 B 54.208 28.482 110.570 1.00 11.26 ? 100 LEU H C 1 ATOM 5557 O O . LEU C 3 106 B 55.205 28.949 111.150 1.00 12.51 ? 100 LEU H O 1 ATOM 5558 C CB . LEU C 3 106 B 53.185 27.277 112.450 1.00 10.72 ? 100 LEU H CB 1 ATOM 5559 C CG . LEU C 3 106 B 51.909 26.649 112.981 1.00 13.42 ? 100 LEU H CG 1 ATOM 5560 C CD1 . LEU C 3 106 B 51.989 25.147 113.185 1.00 12.59 ? 100 LEU H CD1 1 ATOM 5561 C CD2 . LEU C 3 106 B 51.711 27.243 114.357 1.00 13.54 ? 100 LEU H CD2 1 ATOM 5562 N N . SER C 3 107 C 53.672 29.042 109.511 1.00 11.76 ? 100 SER H N 1 ATOM 5563 C CA . SER C 3 107 C 54.172 30.336 109.185 1.00 11.52 ? 100 SER H CA 1 ATOM 5564 C C . SER C 3 107 C 53.088 31.278 109.718 1.00 12.91 ? 100 SER H C 1 ATOM 5565 O O . SER C 3 107 C 51.937 31.305 109.252 1.00 14.65 ? 100 SER H O 1 ATOM 5566 C CB . SER C 3 107 C 54.359 30.357 107.683 1.00 10.93 ? 100 SER H CB 1 ATOM 5567 O OG . SER C 3 107 C 55.176 29.275 107.252 1.00 9.06 ? 100 SER H OG 1 ATOM 5568 N N . ASP C 3 108 ? 53.325 31.902 110.866 1.00 14.03 ? 101 ASP H N 1 ATOM 5569 C CA . ASP C 3 108 ? 52.427 32.948 111.348 1.00 16.16 ? 101 ASP H CA 1 ATOM 5570 C C . ASP C 3 108 ? 53.019 34.244 110.841 1.00 18.18 ? 101 ASP H C 1 ATOM 5571 O O . ASP C 3 108 ? 54.239 34.302 110.754 1.00 21.18 ? 101 ASP H O 1 ATOM 5572 C CB . ASP C 3 108 ? 52.365 32.972 112.864 1.00 16.00 ? 101 ASP H CB 1 ATOM 5573 C CG . ASP C 3 108 ? 53.657 33.198 113.668 1.00 16.08 ? 101 ASP H CG 1 ATOM 5574 O OD1 . ASP C 3 108 ? 54.766 33.251 113.110 1.00 16.99 ? 101 ASP H OD1 1 ATOM 5575 O OD2 . ASP C 3 108 ? 53.540 33.309 114.905 1.00 14.50 ? 101 ASP H OD2 1 ATOM 5576 N N . TYR C 3 109 ? 52.315 35.293 110.457 1.00 17.17 ? 102 TYR H N 1 ATOM 5577 C CA . TYR C 3 109 ? 52.975 36.502 109.917 1.00 16.17 ? 102 TYR H CA 1 ATOM 5578 C C . TYR C 3 109 ? 53.897 36.324 108.678 1.00 13.43 ? 102 TYR H C 1 ATOM 5579 O O . TYR C 3 109 ? 55.066 35.930 108.695 1.00 9.20 ? 102 TYR H O 1 ATOM 5580 C CB . TYR C 3 109 ? 53.757 37.218 111.067 1.00 20.48 ? 102 TYR H CB 1 ATOM 5581 C CG . TYR C 3 109 ? 52.905 37.336 112.329 1.00 24.36 ? 102 TYR H CG 1 ATOM 5582 C CD1 . TYR C 3 109 ? 51.548 37.661 112.304 1.00 25.17 ? 102 TYR H CD1 1 ATOM 5583 C CD2 . TYR C 3 109 ? 53.468 36.982 113.534 1.00 26.62 ? 102 TYR H CD2 1 ATOM 5584 C CE1 . TYR C 3 109 ? 50.767 37.607 113.452 1.00 24.99 ? 102 TYR H CE1 1 ATOM 5585 C CE2 . TYR C 3 109 ? 52.696 36.926 114.684 1.00 26.65 ? 102 TYR H CE2 1 ATOM 5586 C CZ . TYR C 3 109 ? 51.353 37.235 114.646 1.00 25.30 ? 102 TYR H CZ 1 ATOM 5587 O OH . TYR C 3 109 ? 50.612 37.132 115.817 1.00 26.97 ? 102 TYR H OH 1 ATOM 5588 N N . TRP C 3 110 ? 53.316 36.642 107.522 1.00 12.03 ? 103 TRP H N 1 ATOM 5589 C CA . TRP C 3 110 ? 53.954 36.535 106.208 1.00 10.25 ? 103 TRP H CA 1 ATOM 5590 C C . TRP C 3 110 ? 54.341 37.905 105.685 1.00 11.91 ? 103 TRP H C 1 ATOM 5591 O O . TRP C 3 110 ? 53.785 38.942 106.059 1.00 14.66 ? 103 TRP H O 1 ATOM 5592 C CB . TRP C 3 110 ? 53.031 35.927 105.153 1.00 7.71 ? 103 TRP H CB 1 ATOM 5593 C CG . TRP C 3 110 ? 52.638 34.482 105.355 1.00 6.27 ? 103 TRP H CG 1 ATOM 5594 C CD1 . TRP C 3 110 ? 52.002 34.055 106.483 1.00 5.23 ? 103 TRP H CD1 1 ATOM 5595 C CD2 . TRP C 3 110 ? 52.786 33.495 104.403 1.00 4.85 ? 103 TRP H CD2 1 ATOM 5596 N NE1 . TRP C 3 110 ? 51.726 32.803 106.251 1.00 3.50 ? 103 TRP H NE1 1 ATOM 5597 C CE2 . TRP C 3 110 ? 52.163 32.412 105.029 1.00 3.72 ? 103 TRP H CE2 1 ATOM 5598 C CE3 . TRP C 3 110 ? 53.327 33.338 103.123 1.00 5.18 ? 103 TRP H CE3 1 ATOM 5599 C CZ2 . TRP C 3 110 ? 52.083 31.174 104.368 1.00 2.99 ? 103 TRP H CZ2 1 ATOM 5600 C CZ3 . TRP C 3 110 ? 53.239 32.114 102.485 1.00 2.35 ? 103 TRP H CZ3 1 ATOM 5601 C CH2 . TRP C 3 110 ? 52.622 31.038 103.098 1.00 2.02 ? 103 TRP H CH2 1 ATOM 5602 N N . GLY C 3 111 ? 55.275 37.934 104.773 1.00 14.64 ? 104 GLY H N 1 ATOM 5603 C CA . GLY C 3 111 ? 55.664 39.202 104.224 1.00 16.96 ? 104 GLY H CA 1 ATOM 5604 C C . GLY C 3 111 ? 54.850 39.440 102.966 1.00 19.40 ? 104 GLY H C 1 ATOM 5605 O O . GLY C 3 111 ? 54.294 38.507 102.399 1.00 19.85 ? 104 GLY H O 1 ATOM 5606 N N . GLN C 3 112 ? 54.851 40.680 102.485 1.00 20.73 ? 105 GLN H N 1 ATOM 5607 C CA . GLN C 3 112 ? 54.154 41.100 101.272 1.00 21.47 ? 105 GLN H CA 1 ATOM 5608 C C . GLN C 3 112 ? 54.333 40.401 99.925 1.00 19.19 ? 105 GLN H C 1 ATOM 5609 O O . GLN C 3 112 ? 53.476 40.662 99.098 1.00 20.25 ? 105 GLN H O 1 ATOM 5610 C CB . GLN C 3 112 ? 54.434 42.552 101.036 1.00 25.73 ? 105 GLN H CB 1 ATOM 5611 C CG . GLN C 3 112 ? 55.905 42.789 101.133 1.00 33.52 ? 105 GLN H CG 1 ATOM 5612 C CD . GLN C 3 112 ? 56.271 44.022 100.376 1.00 38.88 ? 105 GLN H CD 1 ATOM 5613 O OE1 . GLN C 3 112 ? 56.446 45.091 100.956 1.00 44.07 ? 105 GLN H OE1 1 ATOM 5614 N NE2 . GLN C 3 112 ? 56.433 43.861 99.070 1.00 42.30 ? 105 GLN H NE2 1 ATOM 5615 N N . GLY C 3 113 ? 55.358 39.586 99.601 1.00 17.15 ? 106 GLY H N 1 ATOM 5616 C CA . GLY C 3 113 ? 55.477 38.917 98.307 1.00 14.86 ? 106 GLY H CA 1 ATOM 5617 C C . GLY C 3 113 ? 56.308 39.795 97.389 1.00 13.29 ? 106 GLY H C 1 ATOM 5618 O O . GLY C 3 113 ? 56.194 41.027 97.476 1.00 13.94 ? 106 GLY H O 1 ATOM 5619 N N . THR C 3 114 ? 57.280 39.213 96.662 1.00 12.31 ? 107 THR H N 1 ATOM 5620 C CA . THR C 3 114 ? 58.063 39.918 95.651 1.00 11.77 ? 107 THR H CA 1 ATOM 5621 C C . THR C 3 114 ? 57.901 39.137 94.354 1.00 14.27 ? 107 THR H C 1 ATOM 5622 O O . THR C 3 114 ? 58.084 37.912 94.264 1.00 15.49 ? 107 THR H O 1 ATOM 5623 C CB . THR C 3 114 ? 59.537 39.976 96.090 1.00 11.20 ? 107 THR H CB 1 ATOM 5624 O OG1 . THR C 3 114 ? 59.558 40.967 97.090 1.00 7.97 ? 107 THR H OG1 1 ATOM 5625 C CG2 . THR C 3 114 ? 60.538 40.428 95.047 1.00 10.11 ? 107 THR H CG2 1 ATOM 5626 N N . THR C 3 115 ? 57.508 39.874 93.328 1.00 15.05 ? 108 THR H N 1 ATOM 5627 C CA . THR C 3 115 ? 57.219 39.328 92.019 1.00 16.40 ? 108 THR H CA 1 ATOM 5628 C C . THR C 3 115 ? 58.359 39.377 91.027 1.00 19.49 ? 108 THR H C 1 ATOM 5629 O O . THR C 3 115 ? 59.089 40.363 90.848 1.00 22.98 ? 108 THR H O 1 ATOM 5630 C CB . THR C 3 115 ? 56.037 40.066 91.456 1.00 15.55 ? 108 THR H CB 1 ATOM 5631 O OG1 . THR C 3 115 ? 55.291 40.620 92.563 1.00 16.31 ? 108 THR H OG1 1 ATOM 5632 C CG2 . THR C 3 115 ? 55.240 39.117 90.568 1.00 17.76 ? 108 THR H CG2 1 ATOM 5633 N N . LEU C 3 116 ? 58.446 38.263 90.341 1.00 20.25 ? 109 LEU H N 1 ATOM 5634 C CA . LEU C 3 116 ? 59.554 38.059 89.490 1.00 21.81 ? 109 LEU H CA 1 ATOM 5635 C C . LEU C 3 116 ? 59.016 37.561 88.184 1.00 24.64 ? 109 LEU H C 1 ATOM 5636 O O . LEU C 3 116 ? 58.302 36.547 88.068 1.00 25.42 ? 109 LEU H O 1 ATOM 5637 C CB . LEU C 3 116 ? 60.441 37.058 90.151 1.00 20.58 ? 109 LEU H CB 1 ATOM 5638 C CG . LEU C 3 116 ? 61.786 36.986 89.536 1.00 19.57 ? 109 LEU H CG 1 ATOM 5639 C CD1 . LEU C 3 116 ? 62.417 38.390 89.485 1.00 17.66 ? 109 LEU H CD1 1 ATOM 5640 C CD2 . LEU C 3 116 ? 62.575 35.964 90.309 1.00 18.15 ? 109 LEU H CD2 1 ATOM 5641 N N . THR C 3 117 ? 59.445 38.363 87.226 1.00 28.01 ? 110 THR H N 1 ATOM 5642 C CA . THR C 3 117 ? 59.088 38.170 85.845 1.00 29.87 ? 110 THR H CA 1 ATOM 5643 C C . THR C 3 117 ? 60.453 37.948 85.222 1.00 29.29 ? 110 THR H C 1 ATOM 5644 O O . THR C 3 117 ? 61.325 38.839 85.305 1.00 28.44 ? 110 THR H O 1 ATOM 5645 C CB . THR C 3 117 ? 58.378 39.461 85.356 1.00 31.56 ? 110 THR H CB 1 ATOM 5646 O OG1 . THR C 3 117 ? 57.372 39.779 86.324 1.00 32.55 ? 110 THR H OG1 1 ATOM 5647 C CG2 . THR C 3 117 ? 57.730 39.306 83.989 1.00 32.51 ? 110 THR H CG2 1 ATOM 5648 N N . VAL C 3 118 ? 60.679 36.742 84.682 1.00 28.95 ? 111 VAL H N 1 ATOM 5649 C CA . VAL C 3 118 ? 61.936 36.506 84.016 1.00 27.53 ? 111 VAL H CA 1 ATOM 5650 C C . VAL C 3 118 ? 61.564 36.601 82.551 1.00 27.57 ? 111 VAL H C 1 ATOM 5651 O O . VAL C 3 118 ? 60.946 35.663 82.021 1.00 28.36 ? 111 VAL H O 1 ATOM 5652 C CB . VAL C 3 118 ? 62.529 35.119 84.290 1.00 28.07 ? 111 VAL H CB 1 ATOM 5653 C CG1 . VAL C 3 118 ? 63.998 35.287 84.041 1.00 27.79 ? 111 VAL H CG1 1 ATOM 5654 C CG2 . VAL C 3 118 ? 62.323 34.589 85.696 1.00 29.20 ? 111 VAL H CG2 1 ATOM 5655 N N . SER C 3 119 ? 61.856 37.751 81.914 1.00 27.10 ? 112 SER H N 1 ATOM 5656 C CA . SER C 3 119 ? 61.556 37.971 80.506 1.00 27.62 ? 112 SER H CA 1 ATOM 5657 C C . SER C 3 119 ? 62.674 38.750 79.829 1.00 28.07 ? 112 SER H C 1 ATOM 5658 O O . SER C 3 119 ? 63.424 39.549 80.394 1.00 28.18 ? 112 SER H O 1 ATOM 5659 C CB . SER C 3 119 ? 60.224 38.750 80.331 1.00 28.48 ? 112 SER H CB 1 ATOM 5660 O OG . SER C 3 119 ? 59.703 38.870 78.987 1.00 30.90 ? 112 SER H OG 1 ATOM 5661 N N . SER C 3 120 ? 62.762 38.437 78.544 1.00 29.08 ? 113 SER H N 1 ATOM 5662 C CA . SER C 3 120 ? 63.680 39.078 77.620 1.00 28.88 ? 113 SER H CA 1 ATOM 5663 C C . SER C 3 120 ? 63.060 40.353 77.037 1.00 27.76 ? 113 SER H C 1 ATOM 5664 O O . SER C 3 120 ? 63.745 41.145 76.378 1.00 26.06 ? 113 SER H O 1 ATOM 5665 C CB . SER C 3 120 ? 64.030 38.071 76.505 1.00 28.38 ? 113 SER H CB 1 ATOM 5666 O OG . SER C 3 120 ? 63.354 36.803 76.595 1.00 29.52 ? 113 SER H OG 1 ATOM 5667 N N . ALA C 3 121 ? 61.745 40.533 77.234 1.00 27.48 ? 114 ALA H N 1 ATOM 5668 C CA . ALA C 3 121 ? 61.038 41.685 76.717 1.00 27.44 ? 114 ALA H CA 1 ATOM 5669 C C . ALA C 3 121 ? 61.593 42.994 77.279 1.00 29.17 ? 114 ALA H C 1 ATOM 5670 O O . ALA C 3 121 ? 62.115 43.077 78.398 1.00 32.72 ? 114 ALA H O 1 ATOM 5671 C CB . ALA C 3 121 ? 59.552 41.565 77.063 1.00 26.33 ? 114 ALA H CB 1 ATOM 5672 N N . LYS C 3 122 ? 61.485 44.004 76.411 1.00 29.98 ? 115 LYS H N 1 ATOM 5673 C CA . LYS C 3 122 ? 61.970 45.340 76.684 1.00 30.23 ? 115 LYS H CA 1 ATOM 5674 C C . LYS C 3 122 ? 60.941 46.075 77.540 1.00 31.81 ? 115 LYS H C 1 ATOM 5675 O O . LYS C 3 122 ? 59.713 45.900 77.432 1.00 31.39 ? 115 LYS H O 1 ATOM 5676 C CB . LYS C 3 122 ? 62.165 46.114 75.385 1.00 29.64 ? 115 LYS H CB 1 ATOM 5677 C CG . LYS C 3 122 ? 63.175 45.508 74.417 1.00 29.13 ? 115 LYS H CG 1 ATOM 5678 C CD . LYS C 3 122 ? 63.182 46.239 73.072 1.00 28.86 ? 115 LYS H CD 1 ATOM 5679 C CE . LYS C 3 122 ? 63.586 47.705 73.175 1.00 28.70 ? 115 LYS H CE 1 ATOM 5680 N NZ . LYS C 3 122 ? 64.905 47.842 73.758 1.00 28.49 ? 115 LYS H NZ 1 ATOM 5681 N N . THR C 3 123 ? 61.462 46.921 78.414 1.00 33.76 ? 116 THR H N 1 ATOM 5682 C CA . THR C 3 123 ? 60.625 47.804 79.196 1.00 35.98 ? 116 THR H CA 1 ATOM 5683 C C . THR C 3 123 ? 60.080 48.815 78.196 1.00 35.43 ? 116 THR H C 1 ATOM 5684 O O . THR C 3 123 ? 60.812 49.435 77.415 1.00 36.28 ? 116 THR H O 1 ATOM 5685 C CB . THR C 3 123 ? 61.465 48.504 80.227 1.00 37.22 ? 116 THR H CB 1 ATOM 5686 O OG1 . THR C 3 123 ? 62.178 47.425 80.833 1.00 38.68 ? 116 THR H OG1 1 ATOM 5687 C CG2 . THR C 3 123 ? 60.673 49.430 81.173 1.00 38.24 ? 116 THR H CG2 1 ATOM 5688 N N . THR C 3 124 ? 58.767 48.922 78.220 1.00 36.27 ? 117 THR H N 1 ATOM 5689 C CA . THR C 3 124 ? 58.068 49.807 77.334 1.00 36.37 ? 117 THR H CA 1 ATOM 5690 C C . THR C 3 124 ? 57.145 50.639 78.211 1.00 35.73 ? 117 THR H C 1 ATOM 5691 O O . THR C 3 124 ? 56.481 50.115 79.117 1.00 35.02 ? 117 THR H O 1 ATOM 5692 C CB . THR C 3 124 ? 57.305 48.964 76.367 1.00 36.97 ? 117 THR H CB 1 ATOM 5693 O OG1 . THR C 3 124 ? 58.196 47.978 75.840 1.00 38.67 ? 117 THR H OG1 1 ATOM 5694 C CG2 . THR C 3 124 ? 56.706 49.838 75.290 1.00 36.44 ? 117 THR H CG2 1 ATOM 5695 N N . ALA C 3 125 ? 57.146 51.955 77.988 1.00 35.63 ? 118 ALA H N 1 ATOM 5696 C CA . ALA C 3 125 ? 56.264 52.843 78.733 1.00 34.30 ? 118 ALA H CA 1 ATOM 5697 C C . ALA C 3 125 ? 54.813 52.653 78.255 1.00 33.67 ? 118 ALA H C 1 ATOM 5698 O O . ALA C 3 125 ? 54.657 52.068 77.181 1.00 33.62 ? 118 ALA H O 1 ATOM 5699 C CB . ALA C 3 125 ? 56.731 54.268 78.495 1.00 34.49 ? 118 ALA H CB 1 ATOM 5700 N N . PRO C 3 126 ? 53.726 53.013 78.959 1.00 33.15 ? 119 PRO H N 1 ATOM 5701 C CA . PRO C 3 126 ? 52.372 52.916 78.447 1.00 32.27 ? 119 PRO H CA 1 ATOM 5702 C C . PRO C 3 126 ? 51.953 54.181 77.699 1.00 30.99 ? 119 PRO H C 1 ATOM 5703 O O . PRO C 3 126 ? 52.601 55.247 77.756 1.00 32.58 ? 119 PRO H O 1 ATOM 5704 C CB . PRO C 3 126 ? 51.584 52.642 79.683 1.00 32.60 ? 119 PRO H CB 1 ATOM 5705 C CG . PRO C 3 126 ? 52.268 53.461 80.775 1.00 33.30 ? 119 PRO H CG 1 ATOM 5706 C CD . PRO C 3 126 ? 53.729 53.535 80.333 1.00 33.07 ? 119 PRO H CD 1 ATOM 5707 N N . SER C 3 127 ? 50.848 54.043 76.982 1.00 29.53 ? 120 SER H N 1 ATOM 5708 C CA . SER C 3 127 ? 50.243 55.164 76.302 1.00 29.08 ? 120 SER H CA 1 ATOM 5709 C C . SER C 3 127 ? 48.819 55.152 76.828 1.00 28.32 ? 120 SER H C 1 ATOM 5710 O O . SER C 3 127 ? 48.115 54.138 76.784 1.00 28.57 ? 120 SER H O 1 ATOM 5711 C CB . SER C 3 127 ? 50.337 54.953 74.786 1.00 29.87 ? 120 SER H CB 1 ATOM 5712 O OG . SER C 3 127 ? 51.691 55.170 74.353 1.00 30.25 ? 120 SER H OG 1 ATOM 5713 N N . VAL C 3 128 ? 48.467 56.277 77.451 1.00 26.66 ? 121 VAL H N 1 ATOM 5714 C CA . VAL C 3 128 ? 47.226 56.395 78.189 1.00 25.67 ? 121 VAL H CA 1 ATOM 5715 C C . VAL C 3 128 ? 46.224 57.196 77.369 1.00 26.86 ? 121 VAL H C 1 ATOM 5716 O O . VAL C 3 128 ? 46.601 58.168 76.702 1.00 25.81 ? 121 VAL H O 1 ATOM 5717 C CB . VAL C 3 128 ? 47.590 57.054 79.535 1.00 24.68 ? 121 VAL H CB 1 ATOM 5718 C CG1 . VAL C 3 128 ? 46.346 57.235 80.346 1.00 23.12 ? 121 VAL H CG1 1 ATOM 5719 C CG2 . VAL C 3 128 ? 48.581 56.183 80.307 1.00 21.56 ? 121 VAL H CG2 1 ATOM 5720 N N . TYR C 3 129 ? 44.972 56.725 77.349 1.00 28.49 ? 122 TYR H N 1 ATOM 5721 C CA . TYR C 3 129 ? 43.870 57.372 76.631 1.00 29.03 ? 122 TYR H CA 1 ATOM 5722 C C . TYR C 3 129 ? 42.680 57.598 77.568 1.00 28.77 ? 122 TYR H C 1 ATOM 5723 O O . TYR C 3 129 ? 42.394 56.705 78.388 1.00 27.72 ? 122 TYR H O 1 ATOM 5724 C CB . TYR C 3 129 ? 43.414 56.495 75.458 1.00 30.26 ? 122 TYR H CB 1 ATOM 5725 C CG . TYR C 3 129 ? 44.581 56.195 74.557 1.00 30.62 ? 122 TYR H CG 1 ATOM 5726 C CD1 . TYR C 3 129 ? 45.329 57.244 74.071 1.00 29.97 ? 122 TYR H CD1 1 ATOM 5727 C CD2 . TYR C 3 129 ? 44.910 54.889 74.271 1.00 31.14 ? 122 TYR H CD2 1 ATOM 5728 C CE1 . TYR C 3 129 ? 46.435 56.993 73.283 1.00 30.07 ? 122 TYR H CE1 1 ATOM 5729 C CE2 . TYR C 3 129 ? 46.016 54.629 73.477 1.00 31.35 ? 122 TYR H CE2 1 ATOM 5730 C CZ . TYR C 3 129 ? 46.780 55.685 72.986 1.00 30.55 ? 122 TYR H CZ 1 ATOM 5731 O OH . TYR C 3 129 ? 47.887 55.445 72.178 1.00 31.27 ? 122 TYR H OH 1 ATOM 5732 N N . PRO C 3 130 ? 41.995 58.768 77.526 1.00 28.94 ? 123 PRO H N 1 ATOM 5733 C CA . PRO C 3 130 ? 40.753 59.048 78.242 1.00 28.95 ? 123 PRO H CA 1 ATOM 5734 C C . PRO C 3 130 ? 39.566 58.581 77.430 1.00 27.66 ? 123 PRO H C 1 ATOM 5735 O O . PRO C 3 130 ? 39.350 58.974 76.273 1.00 28.48 ? 123 PRO H O 1 ATOM 5736 C CB . PRO C 3 130 ? 40.806 60.545 78.484 1.00 29.09 ? 123 PRO H CB 1 ATOM 5737 C CG . PRO C 3 130 ? 41.437 61.066 77.230 1.00 30.00 ? 123 PRO H CG 1 ATOM 5738 C CD . PRO C 3 130 ? 42.476 59.987 76.904 1.00 28.98 ? 123 PRO H CD 1 ATOM 5739 N N . LEU C 3 131 ? 38.796 57.707 78.037 1.00 26.80 ? 124 LEU H N 1 ATOM 5740 C CA . LEU C 3 131 ? 37.720 57.099 77.306 1.00 27.20 ? 124 LEU H CA 1 ATOM 5741 C C . LEU C 3 131 ? 36.446 57.797 77.709 1.00 26.88 ? 124 LEU H C 1 ATOM 5742 O O . LEU C 3 131 ? 35.816 57.443 78.704 1.00 25.76 ? 124 LEU H O 1 ATOM 5743 C CB . LEU C 3 131 ? 37.699 55.618 77.635 1.00 28.26 ? 124 LEU H CB 1 ATOM 5744 C CG . LEU C 3 131 ? 38.997 54.832 77.477 1.00 29.39 ? 124 LEU H CG 1 ATOM 5745 C CD1 . LEU C 3 131 ? 38.625 53.383 77.685 1.00 29.62 ? 124 LEU H CD1 1 ATOM 5746 C CD2 . LEU C 3 131 ? 39.678 55.075 76.125 1.00 29.89 ? 124 LEU H CD2 1 ATOM 5747 N N . ALA C 3 132 ? 36.135 58.866 76.970 1.00 28.24 ? 125 ALA H N 1 ATOM 5748 C CA . ALA C 3 132 ? 34.920 59.639 77.189 1.00 29.73 ? 125 ALA H CA 1 ATOM 5749 C C . ALA C 3 132 ? 33.827 58.885 76.469 1.00 31.08 ? 125 ALA H C 1 ATOM 5750 O O . ALA C 3 132 ? 34.139 58.070 75.594 1.00 30.63 ? 125 ALA H O 1 ATOM 5751 C CB . ALA C 3 132 ? 34.999 61.022 76.584 1.00 31.18 ? 125 ALA H CB 1 ATOM 5752 N N . PRO C 3 133 ? 32.556 59.016 76.834 1.00 32.88 ? 126 PRO H N 1 ATOM 5753 C CA . PRO C 3 133 ? 31.489 58.332 76.132 1.00 34.88 ? 126 PRO H CA 1 ATOM 5754 C C . PRO C 3 133 ? 30.903 59.200 75.028 1.00 38.14 ? 126 PRO H C 1 ATOM 5755 O O . PRO C 3 133 ? 31.022 60.433 75.016 1.00 39.56 ? 126 PRO H O 1 ATOM 5756 C CB . PRO C 3 133 ? 30.542 57.996 77.241 1.00 33.40 ? 126 PRO H CB 1 ATOM 5757 C CG . PRO C 3 133 ? 30.600 59.252 78.086 1.00 33.10 ? 126 PRO H CG 1 ATOM 5758 C CD . PRO C 3 133 ? 32.071 59.641 78.070 1.00 32.53 ? 126 PRO H CD 1 ATOM 5759 N N . VAL C 3 134 ? 30.235 58.557 74.073 1.00 39.69 ? 127 VAL H N 1 ATOM 5760 C CA . VAL C 3 134 ? 29.453 59.238 73.047 1.00 41.78 ? 127 VAL H CA 1 ATOM 5761 C C . VAL C 3 134 ? 28.128 59.483 73.820 1.00 43.24 ? 127 VAL H C 1 ATOM 5762 O O . VAL C 3 134 ? 27.070 58.887 73.590 1.00 45.16 ? 127 VAL H O 1 ATOM 5763 C CB . VAL C 3 134 ? 29.417 58.225 71.823 1.00 41.90 ? 127 VAL H CB 1 ATOM 5764 C CG1 . VAL C 3 134 ? 28.801 56.854 72.174 1.00 42.94 ? 127 VAL H CG1 1 ATOM 5765 C CG2 . VAL C 3 134 ? 28.643 58.908 70.687 1.00 43.42 ? 127 VAL H CG2 1 ATOM 5766 N N . CYS C 3 135 ? 28.237 60.375 74.812 1.00 42.72 ? 128 CYS H N 1 ATOM 5767 C CA . CYS C 3 135 ? 27.261 60.611 75.875 1.00 42.58 ? 128 CYS H CA 1 ATOM 5768 C C . CYS C 3 135 ? 26.701 59.309 76.459 1.00 42.41 ? 128 CYS H C 1 ATOM 5769 O O . CYS C 3 135 ? 27.525 58.571 76.992 1.00 42.57 ? 128 CYS H O 1 ATOM 5770 C CB . CYS C 3 135 ? 26.120 61.517 75.381 1.00 42.64 ? 128 CYS H CB 1 ATOM 5771 S SG . CYS C 3 135 ? 24.966 60.977 74.098 1.00 43.17 ? 128 CYS H SG 1 ATOM 5772 N N . GLY C 3 136 ? 25.425 58.906 76.425 1.00 42.33 ? 129 GLY H N 1 ATOM 5773 C CA . GLY C 3 136 ? 24.989 57.636 77.000 1.00 42.42 ? 129 GLY H CA 1 ATOM 5774 C C . GLY C 3 136 ? 24.981 57.596 78.527 1.00 42.94 ? 129 GLY H C 1 ATOM 5775 O O . GLY C 3 136 ? 25.915 57.116 79.172 1.00 43.18 ? 129 GLY H O 1 ATOM 5776 N N . ASP C 3 137 ? 23.883 58.060 79.130 1.00 43.50 ? 130 ASP H N 1 ATOM 5777 C CA . ASP C 3 137 ? 23.733 58.062 80.581 1.00 44.28 ? 130 ASP H CA 1 ATOM 5778 C C . ASP C 3 137 ? 23.710 56.610 81.051 1.00 44.65 ? 130 ASP H C 1 ATOM 5779 O O . ASP C 3 137 ? 22.788 55.837 80.762 1.00 45.50 ? 130 ASP H O 1 ATOM 5780 C CB . ASP C 3 137 ? 22.432 58.784 80.951 1.00 44.43 ? 130 ASP H CB 1 ATOM 5781 C CG . ASP C 3 137 ? 22.228 59.050 82.439 1.00 44.80 ? 130 ASP H CG 1 ATOM 5782 O OD1 . ASP C 3 137 ? 23.094 59.663 83.070 1.00 45.75 ? 130 ASP H OD1 1 ATOM 5783 O OD2 . ASP C 3 137 ? 21.188 58.658 82.967 1.00 44.63 ? 130 ASP H OD2 1 ATOM 5784 N N . THR C 3 138 ? 24.799 56.217 81.696 1.00 44.95 ? 133 THR H N 1 ATOM 5785 C CA . THR C 3 138 ? 24.983 54.860 82.144 1.00 45.14 ? 133 THR H CA 1 ATOM 5786 C C . THR C 3 138 ? 24.179 54.617 83.412 1.00 44.67 ? 133 THR H C 1 ATOM 5787 O O . THR C 3 138 ? 24.641 54.794 84.544 1.00 44.99 ? 133 THR H O 1 ATOM 5788 C CB . THR C 3 138 ? 26.484 54.608 82.393 1.00 45.58 ? 133 THR H CB 1 ATOM 5789 O OG1 . THR C 3 138 ? 27.270 55.596 81.719 1.00 45.41 ? 133 THR H OG1 1 ATOM 5790 C CG2 . THR C 3 138 ? 26.835 53.217 81.910 1.00 46.21 ? 133 THR H CG2 1 ATOM 5791 N N . THR C 3 139 ? 22.943 54.174 83.181 1.00 44.06 ? 134 THR H N 1 ATOM 5792 C CA . THR C 3 139 ? 21.962 53.821 84.205 1.00 43.72 ? 134 THR H CA 1 ATOM 5793 C C . THR C 3 139 ? 21.454 55.113 84.867 1.00 42.93 ? 134 THR H C 1 ATOM 5794 O O . THR C 3 139 ? 21.651 56.202 84.316 1.00 42.58 ? 134 THR H O 1 ATOM 5795 C CB . THR C 3 139 ? 22.592 52.834 85.258 1.00 44.02 ? 134 THR H CB 1 ATOM 5796 O OG1 . THR C 3 139 ? 23.552 52.024 84.584 1.00 44.27 ? 134 THR H OG1 1 ATOM 5797 C CG2 . THR C 3 139 ? 21.557 51.912 85.891 1.00 44.45 ? 134 THR H CG2 1 ATOM 5798 N N . GLY C 3 140 ? 20.778 55.094 86.021 1.00 42.41 ? 135 GLY H N 1 ATOM 5799 C CA . GLY C 3 140 ? 20.203 56.289 86.621 1.00 41.13 ? 135 GLY H CA 1 ATOM 5800 C C . GLY C 3 140 ? 21.229 57.344 87.000 1.00 40.25 ? 135 GLY H C 1 ATOM 5801 O O . GLY C 3 140 ? 22.100 57.089 87.832 1.00 39.68 ? 135 GLY H O 1 ATOM 5802 N N . SER C 3 141 ? 21.149 58.479 86.302 1.00 39.30 ? 136 SER H N 1 ATOM 5803 C CA . SER C 3 141 ? 21.951 59.674 86.536 1.00 38.71 ? 136 SER H CA 1 ATOM 5804 C C . SER C 3 141 ? 23.430 59.490 86.865 1.00 38.42 ? 136 SER H C 1 ATOM 5805 O O . SER C 3 141 ? 24.056 60.189 87.673 1.00 37.68 ? 136 SER H O 1 ATOM 5806 C CB . SER C 3 141 ? 21.258 60.470 87.633 1.00 38.37 ? 136 SER H CB 1 ATOM 5807 O OG . SER C 3 141 ? 19.948 60.847 87.220 1.00 38.50 ? 136 SER H OG 1 ATOM 5808 N N . SER C 3 142 ? 23.997 58.563 86.126 1.00 39.51 ? 137 SER H N 1 ATOM 5809 C CA . SER C 3 142 ? 25.374 58.173 86.275 1.00 38.23 ? 137 SER H CA 1 ATOM 5810 C C . SER C 3 142 ? 25.985 58.090 84.877 1.00 35.75 ? 137 SER H C 1 ATOM 5811 O O . SER C 3 142 ? 25.360 57.703 83.875 1.00 36.34 ? 137 SER H O 1 ATOM 5812 C CB . SER C 3 142 ? 25.446 56.809 87.000 1.00 41.06 ? 137 SER H CB 1 ATOM 5813 O OG . SER C 3 142 ? 24.956 56.794 88.358 1.00 44.24 ? 137 SER H OG 1 ATOM 5814 N N . VAL C 3 143 ? 27.211 58.573 84.806 1.00 31.85 ? 138 VAL H N 1 ATOM 5815 C CA . VAL C 3 143 ? 27.992 58.566 83.605 1.00 28.13 ? 138 VAL H CA 1 ATOM 5816 C C . VAL C 3 143 ? 29.202 57.753 84.030 1.00 26.43 ? 138 VAL H C 1 ATOM 5817 O O . VAL C 3 143 ? 29.696 57.868 85.164 1.00 27.24 ? 138 VAL H O 1 ATOM 5818 C CB . VAL C 3 143 ? 28.296 60.007 83.258 1.00 27.26 ? 138 VAL H CB 1 ATOM 5819 C CG1 . VAL C 3 143 ? 29.355 60.671 84.097 1.00 24.87 ? 138 VAL H CG1 1 ATOM 5820 C CG2 . VAL C 3 143 ? 28.732 59.941 81.829 1.00 29.47 ? 138 VAL H CG2 1 ATOM 5821 N N . THR C 3 144 ? 29.665 56.877 83.163 1.00 24.41 ? 139 THR H N 1 ATOM 5822 C CA . THR C 3 144 ? 30.797 56.029 83.494 1.00 23.54 ? 139 THR H CA 1 ATOM 5823 C C . THR C 3 144 ? 31.823 56.473 82.470 1.00 22.81 ? 139 THR H C 1 ATOM 5824 O O . THR C 3 144 ? 31.484 56.676 81.301 1.00 23.64 ? 139 THR H O 1 ATOM 5825 C CB . THR C 3 144 ? 30.461 54.535 83.305 1.00 23.70 ? 139 THR H CB 1 ATOM 5826 O OG1 . THR C 3 144 ? 29.535 54.143 84.299 1.00 25.66 ? 139 THR H OG1 1 ATOM 5827 C CG2 . THR C 3 144 ? 31.689 53.666 83.412 1.00 24.07 ? 139 THR H CG2 1 ATOM 5828 N N . LEU C 3 145 ? 33.058 56.696 82.861 1.00 22.32 ? 140 LEU H N 1 ATOM 5829 C CA . LEU C 3 145 ? 34.049 57.112 81.924 1.00 24.53 ? 140 LEU H CA 1 ATOM 5830 C C . LEU C 3 145 ? 35.268 56.357 82.363 1.00 23.51 ? 140 LEU H C 1 ATOM 5831 O O . LEU C 3 145 ? 35.359 55.841 83.480 1.00 25.29 ? 140 LEU H O 1 ATOM 5832 C CB . LEU C 3 145 ? 34.167 58.634 81.992 1.00 26.31 ? 140 LEU H CB 1 ATOM 5833 C CG . LEU C 3 145 ? 34.485 59.500 83.203 1.00 28.43 ? 140 LEU H CG 1 ATOM 5834 C CD1 . LEU C 3 145 ? 34.099 60.879 82.748 1.00 28.59 ? 140 LEU H CD1 1 ATOM 5835 C CD2 . LEU C 3 145 ? 33.649 59.282 84.438 1.00 30.99 ? 140 LEU H CD2 1 ATOM 5836 N N . GLY C 3 146 ? 36.114 56.150 81.381 1.00 21.32 ? 141 GLY H N 1 ATOM 5837 C CA . GLY C 3 146 ? 37.242 55.279 81.575 1.00 21.73 ? 141 GLY H CA 1 ATOM 5838 C C . GLY C 3 146 ? 38.565 55.877 81.181 1.00 21.54 ? 141 GLY H C 1 ATOM 5839 O O . GLY C 3 146 ? 38.666 57.046 80.790 1.00 21.82 ? 141 GLY H O 1 ATOM 5840 N N . CYS C 3 147 ? 39.566 55.021 81.333 1.00 21.93 ? 142 CYS H N 1 ATOM 5841 C CA . CYS C 3 147 ? 40.946 55.342 81.042 1.00 22.76 ? 142 CYS H CA 1 ATOM 5842 C C . CYS C 3 147 ? 41.613 54.032 80.700 1.00 23.90 ? 142 CYS H C 1 ATOM 5843 O O . CYS C 3 147 ? 41.483 53.043 81.434 1.00 24.47 ? 142 CYS H O 1 ATOM 5844 C CB . CYS C 3 147 ? 41.536 55.979 82.271 1.00 22.53 ? 142 CYS H CB 1 ATOM 5845 S SG . CYS C 3 147 ? 43.306 56.362 82.271 1.00 22.93 ? 142 CYS H SG 1 ATOM 5846 N N . LEU C 3 148 ? 42.226 54.022 79.522 1.00 25.08 ? 143 LEU H N 1 ATOM 5847 C CA . LEU C 3 148 ? 42.894 52.847 78.997 1.00 24.69 ? 143 LEU H CA 1 ATOM 5848 C C . LEU C 3 148 ? 44.393 53.121 78.951 1.00 23.62 ? 143 LEU H C 1 ATOM 5849 O O . LEU C 3 148 ? 44.885 54.075 78.320 1.00 24.23 ? 143 LEU H O 1 ATOM 5850 C CB . LEU C 3 148 ? 42.428 52.526 77.584 1.00 24.61 ? 143 LEU H CB 1 ATOM 5851 C CG . LEU C 3 148 ? 42.775 51.165 77.032 1.00 24.97 ? 143 LEU H CG 1 ATOM 5852 C CD1 . LEU C 3 148 ? 41.782 50.142 77.549 1.00 26.33 ? 143 LEU H CD1 1 ATOM 5853 C CD2 . LEU C 3 148 ? 42.712 51.205 75.524 1.00 25.00 ? 143 LEU H CD2 1 ATOM 5854 N N . VAL C 3 149 ? 45.101 52.225 79.645 1.00 20.52 ? 144 VAL H N 1 ATOM 5855 C CA . VAL C 3 149 ? 46.540 52.254 79.734 1.00 21.73 ? 144 VAL H CA 1 ATOM 5856 C C . VAL C 3 149 ? 46.961 51.160 78.754 1.00 22.46 ? 144 VAL H C 1 ATOM 5857 O O . VAL C 3 149 ? 46.666 49.976 78.977 1.00 25.25 ? 144 VAL H O 1 ATOM 5858 C CB . VAL C 3 149 ? 46.923 51.929 81.155 1.00 21.16 ? 144 VAL H CB 1 ATOM 5859 C CG1 . VAL C 3 149 ? 48.445 51.928 81.213 1.00 20.11 ? 144 VAL H CG1 1 ATOM 5860 C CG2 . VAL C 3 149 ? 46.293 52.892 82.127 1.00 21.19 ? 144 VAL H CG2 1 ATOM 5861 N N . LYS C 3 150 ? 47.597 51.532 77.651 1.00 23.33 ? 145 LYS H N 1 ATOM 5862 C CA . LYS C 3 150 ? 47.926 50.563 76.620 1.00 23.90 ? 145 LYS H CA 1 ATOM 5863 C C . LYS C 3 150 ? 49.416 50.397 76.319 1.00 23.30 ? 145 LYS H C 1 ATOM 5864 O O . LYS C 3 150 ? 50.181 51.371 76.366 1.00 21.23 ? 145 LYS H O 1 ATOM 5865 C CB . LYS C 3 150 ? 47.222 50.944 75.327 1.00 24.11 ? 145 LYS H CB 1 ATOM 5866 C CG . LYS C 3 150 ? 46.555 49.758 74.655 1.00 24.13 ? 145 LYS H CG 1 ATOM 5867 C CD . LYS C 3 150 ? 46.656 49.869 73.126 1.00 24.11 ? 145 LYS H CD 1 ATOM 5868 C CE . LYS C 3 150 ? 45.958 48.712 72.388 1.00 25.37 ? 145 LYS H CE 1 ATOM 5869 N NZ . LYS C 3 150 ? 46.389 47.398 72.837 1.00 25.20 ? 145 LYS H NZ 1 ATOM 5870 N N . GLY C 3 151 ? 49.779 49.141 76.009 1.00 23.55 ? 146 GLY H N 1 ATOM 5871 C CA . GLY C 3 151 ? 51.110 48.713 75.578 1.00 25.15 ? 146 GLY H CA 1 ATOM 5872 C C . GLY C 3 151 ? 52.342 49.115 76.390 1.00 25.70 ? 146 GLY H C 1 ATOM 5873 O O . GLY C 3 151 ? 53.122 49.951 75.944 1.00 28.57 ? 146 GLY H O 1 ATOM 5874 N N . TYR C 3 152 ? 52.587 48.479 77.527 1.00 25.08 ? 147 TYR H N 1 ATOM 5875 C CA . TYR C 3 152 ? 53.753 48.766 78.357 1.00 24.48 ? 147 TYR H CA 1 ATOM 5876 C C . TYR C 3 152 ? 54.403 47.452 78.772 1.00 24.03 ? 147 TYR H C 1 ATOM 5877 O O . TYR C 3 152 ? 53.793 46.391 78.556 1.00 22.63 ? 147 TYR H O 1 ATOM 5878 C CB . TYR C 3 152 ? 53.345 49.556 79.633 1.00 26.65 ? 147 TYR H CB 1 ATOM 5879 C CG . TYR C 3 152 ? 52.294 48.946 80.567 1.00 29.21 ? 147 TYR H CG 1 ATOM 5880 C CD1 . TYR C 3 152 ? 50.947 49.166 80.316 1.00 29.35 ? 147 TYR H CD1 1 ATOM 5881 C CD2 . TYR C 3 152 ? 52.669 48.174 81.657 1.00 28.84 ? 147 TYR H CD2 1 ATOM 5882 C CE1 . TYR C 3 152 ? 49.983 48.619 81.146 1.00 29.73 ? 147 TYR H CE1 1 ATOM 5883 C CE2 . TYR C 3 152 ? 51.710 47.619 82.488 1.00 28.96 ? 147 TYR H CE2 1 ATOM 5884 C CZ . TYR C 3 152 ? 50.370 47.845 82.226 1.00 29.60 ? 147 TYR H CZ 1 ATOM 5885 O OH . TYR C 3 152 ? 49.394 47.286 83.032 1.00 29.55 ? 147 TYR H OH 1 ATOM 5886 N N . PHE C 3 153 ? 55.577 47.482 79.413 1.00 23.03 ? 148 PHE H N 1 ATOM 5887 C CA . PHE C 3 153 ? 56.202 46.303 79.993 1.00 21.29 ? 148 PHE H CA 1 ATOM 5888 C C . PHE C 3 153 ? 57.190 46.852 80.997 1.00 20.89 ? 148 PHE H C 1 ATOM 5889 O O . PHE C 3 153 ? 57.953 47.756 80.668 1.00 20.59 ? 148 PHE H O 1 ATOM 5890 C CB . PHE C 3 153 ? 57.001 45.456 78.994 1.00 19.79 ? 148 PHE H CB 1 ATOM 5891 C CG . PHE C 3 153 ? 57.235 44.024 79.501 1.00 19.51 ? 148 PHE H CG 1 ATOM 5892 C CD1 . PHE C 3 153 ? 56.164 43.122 79.513 1.00 18.91 ? 148 PHE H CD1 1 ATOM 5893 C CD2 . PHE C 3 153 ? 58.500 43.614 79.955 1.00 19.13 ? 148 PHE H CD2 1 ATOM 5894 C CE1 . PHE C 3 153 ? 56.363 41.818 79.937 1.00 18.59 ? 148 PHE H CE1 1 ATOM 5895 C CE2 . PHE C 3 153 ? 58.693 42.303 80.373 1.00 18.21 ? 148 PHE H CE2 1 ATOM 5896 C CZ . PHE C 3 153 ? 57.618 41.421 80.374 1.00 19.64 ? 148 PHE H CZ 1 ATOM 5897 N N . PRO C 3 154 ? 57.283 46.354 82.210 1.00 20.34 ? 149 PRO H N 1 ATOM 5898 C CA . PRO C 3 154 ? 56.475 45.258 82.705 1.00 22.63 ? 149 PRO H CA 1 ATOM 5899 C C . PRO C 3 154 ? 55.324 45.722 83.619 1.00 25.56 ? 149 PRO H C 1 ATOM 5900 O O . PRO C 3 154 ? 55.034 46.916 83.749 1.00 26.03 ? 149 PRO H O 1 ATOM 5901 C CB . PRO C 3 154 ? 57.539 44.403 83.361 1.00 21.55 ? 149 PRO H CB 1 ATOM 5902 C CG . PRO C 3 154 ? 58.422 45.461 84.045 1.00 18.33 ? 149 PRO H CG 1 ATOM 5903 C CD . PRO C 3 154 ? 58.346 46.698 83.156 1.00 18.83 ? 149 PRO H CD 1 ATOM 5904 N N . GLU C 3 155 ? 54.628 44.731 84.205 1.00 30.14 ? 150 GLU H N 1 ATOM 5905 C CA . GLU C 3 155 ? 53.620 44.989 85.216 1.00 34.63 ? 150 GLU H CA 1 ATOM 5906 C C . GLU C 3 155 ? 54.469 45.441 86.392 1.00 31.95 ? 150 GLU H C 1 ATOM 5907 O O . GLU C 3 155 ? 55.568 44.874 86.521 1.00 31.41 ? 150 GLU H O 1 ATOM 5908 C CB . GLU C 3 155 ? 52.904 43.698 85.530 1.00 38.27 ? 150 GLU H CB 1 ATOM 5909 C CG . GLU C 3 155 ? 51.556 43.712 84.884 1.00 44.15 ? 150 GLU H CG 1 ATOM 5910 C CD . GLU C 3 155 ? 50.577 44.584 85.648 1.00 48.44 ? 150 GLU H CD 1 ATOM 5911 O OE1 . GLU C 3 155 ? 50.051 44.099 86.643 1.00 49.75 ? 150 GLU H OE1 1 ATOM 5912 O OE2 . GLU C 3 155 ? 50.334 45.730 85.264 1.00 53.40 ? 150 GLU H OE2 1 ATOM 5913 N N . PRO C 3 156 ? 54.091 46.385 87.255 1.00 29.83 ? 151 PRO H N 1 ATOM 5914 C CA . PRO C 3 156 ? 52.802 47.062 87.289 1.00 30.80 ? 151 PRO H CA 1 ATOM 5915 C C . PRO C 3 156 ? 52.669 48.503 86.795 1.00 30.99 ? 151 PRO H C 1 ATOM 5916 O O . PRO C 3 156 ? 53.619 49.210 86.441 1.00 34.18 ? 151 PRO H O 1 ATOM 5917 C CB . PRO C 3 156 ? 52.442 46.916 88.725 1.00 31.14 ? 151 PRO H CB 1 ATOM 5918 C CG . PRO C 3 156 ? 53.763 47.320 89.370 1.00 31.63 ? 151 PRO H CG 1 ATOM 5919 C CD . PRO C 3 156 ? 54.807 46.637 88.501 1.00 31.44 ? 151 PRO H CD 1 ATOM 5920 N N . VAL C 3 157 ? 51.434 48.976 86.889 1.00 30.42 ? 152 VAL H N 1 ATOM 5921 C CA . VAL C 3 157 ? 51.133 50.364 86.648 1.00 29.87 ? 152 VAL H CA 1 ATOM 5922 C C . VAL C 3 157 ? 50.171 50.722 87.766 1.00 28.39 ? 152 VAL H C 1 ATOM 5923 O O . VAL C 3 157 ? 49.376 49.892 88.228 1.00 30.84 ? 152 VAL H O 1 ATOM 5924 C CB . VAL C 3 157 ? 50.488 50.512 85.288 1.00 29.87 ? 152 VAL H CB 1 ATOM 5925 C CG1 . VAL C 3 157 ? 49.804 51.870 85.172 1.00 30.27 ? 152 VAL H CG1 1 ATOM 5926 C CG2 . VAL C 3 157 ? 51.575 50.457 84.235 1.00 31.51 ? 152 VAL H CG2 1 ATOM 5927 N N . THR C 3 158 ? 50.231 51.971 88.195 1.00 26.59 ? 153 THR H N 1 ATOM 5928 C CA . THR C 3 158 ? 49.446 52.455 89.309 1.00 26.07 ? 153 THR H CA 1 ATOM 5929 C C . THR C 3 158 ? 48.456 53.460 88.715 1.00 26.19 ? 153 THR H C 1 ATOM 5930 O O . THR C 3 158 ? 48.818 54.595 88.358 1.00 26.87 ? 153 THR H O 1 ATOM 5931 C CB . THR C 3 158 ? 50.541 53.016 90.283 1.00 25.37 ? 153 THR H CB 1 ATOM 5932 O OG1 . THR C 3 158 ? 51.232 51.852 90.724 1.00 25.56 ? 153 THR H OG1 1 ATOM 5933 C CG2 . THR C 3 158 ? 50.070 53.789 91.477 1.00 23.76 ? 153 THR H CG2 1 ATOM 5934 N N . LEU C 3 159 ? 47.239 52.969 88.477 1.00 25.11 ? 154 LEU H N 1 ATOM 5935 C CA . LEU C 3 159 ? 46.144 53.813 88.013 1.00 24.32 ? 154 LEU H CA 1 ATOM 5936 C C . LEU C 3 159 ? 45.351 54.283 89.250 1.00 25.80 ? 154 LEU H C 1 ATOM 5937 O O . LEU C 3 159 ? 45.031 53.486 90.149 1.00 26.11 ? 154 LEU H O 1 ATOM 5938 C CB . LEU C 3 159 ? 45.231 53.026 87.067 1.00 23.22 ? 154 LEU H CB 1 ATOM 5939 C CG . LEU C 3 159 ? 44.383 53.852 86.116 1.00 21.78 ? 154 LEU H CG 1 ATOM 5940 C CD1 . LEU C 3 159 ? 44.023 52.998 84.940 1.00 21.48 ? 154 LEU H CD1 1 ATOM 5941 C CD2 . LEU C 3 159 ? 43.141 54.375 86.809 1.00 24.34 ? 154 LEU H CD2 1 ATOM 5942 N N . THR C 3 160 ? 45.076 55.590 89.352 1.00 27.65 ? 156 THR H N 1 ATOM 5943 C CA . THR C 3 160 ? 44.260 56.157 90.414 1.00 27.63 ? 156 THR H CA 1 ATOM 5944 C C . THR C 3 160 ? 43.337 57.168 89.706 1.00 27.90 ? 156 THR H C 1 ATOM 5945 O O . THR C 3 160 ? 43.739 57.779 88.696 1.00 26.99 ? 156 THR H O 1 ATOM 5946 C CB . THR C 3 160 ? 45.216 56.813 91.524 1.00 28.04 ? 156 THR H CB 1 ATOM 5947 O OG1 . THR C 3 160 ? 44.632 58.062 91.903 1.00 28.47 ? 156 THR H OG1 1 ATOM 5948 C CG2 . THR C 3 160 ? 46.675 56.997 91.073 1.00 26.88 ? 156 THR H CG2 1 ATOM 5949 N N . TRP C 3 161 ? 42.071 57.342 90.139 1.00 28.56 ? 157 TRP H N 1 ATOM 5950 C CA . TRP C 3 161 ? 41.258 58.415 89.563 1.00 28.43 ? 157 TRP H CA 1 ATOM 5951 C C . TRP C 3 161 ? 41.215 59.431 90.663 1.00 27.77 ? 157 TRP H C 1 ATOM 5952 O O . TRP C 3 161 ? 41.140 59.194 91.879 1.00 25.14 ? 157 TRP H O 1 ATOM 5953 C CB . TRP C 3 161 ? 39.807 58.100 89.263 1.00 29.38 ? 157 TRP H CB 1 ATOM 5954 C CG . TRP C 3 161 ? 39.676 57.125 88.131 1.00 30.34 ? 157 TRP H CG 1 ATOM 5955 C CD1 . TRP C 3 161 ? 39.842 55.791 88.361 1.00 30.23 ? 157 TRP H CD1 1 ATOM 5956 C CD2 . TRP C 3 161 ? 39.391 57.414 86.835 1.00 30.38 ? 157 TRP H CD2 1 ATOM 5957 N NE1 . TRP C 3 161 ? 39.653 55.221 87.202 1.00 29.72 ? 157 TRP H NE1 1 ATOM 5958 C CE2 . TRP C 3 161 ? 39.377 56.147 86.272 1.00 29.69 ? 157 TRP H CE2 1 ATOM 5959 C CE3 . TRP C 3 161 ? 39.134 58.517 86.073 1.00 31.49 ? 157 TRP H CE3 1 ATOM 5960 C CZ2 . TRP C 3 161 ? 39.113 55.930 84.937 1.00 29.83 ? 157 TRP H CZ2 1 ATOM 5961 C CZ3 . TRP C 3 161 ? 38.870 58.307 84.736 1.00 32.12 ? 157 TRP H CZ3 1 ATOM 5962 C CH2 . TRP C 3 161 ? 38.854 57.040 84.178 1.00 30.94 ? 157 TRP H CH2 1 ATOM 5963 N N . ASN C 3 162 ? 41.461 60.567 90.047 1.00 29.17 ? 162 ASN H N 1 ATOM 5964 C CA . ASN C 3 162 ? 41.552 61.845 90.690 1.00 30.72 ? 162 ASN H CA 1 ATOM 5965 C C . ASN C 3 162 ? 42.299 61.893 91.997 1.00 31.49 ? 162 ASN H C 1 ATOM 5966 O O . ASN C 3 162 ? 41.809 62.269 93.076 1.00 31.97 ? 162 ASN H O 1 ATOM 5967 C CB . ASN C 3 162 ? 40.174 62.427 90.880 1.00 29.28 ? 162 ASN H CB 1 ATOM 5968 C CG . ASN C 3 162 ? 40.076 63.361 89.696 1.00 28.57 ? 162 ASN H CG 1 ATOM 5969 O OD1 . ASN C 3 162 ? 39.299 63.084 88.807 1.00 27.53 ? 162 ASN H OD1 1 ATOM 5970 N ND2 . ASN C 3 162 ? 40.840 64.420 89.457 1.00 28.83 ? 162 ASN H ND2 1 ATOM 5971 N N . SER C 3 163 ? 43.554 61.454 91.793 1.00 31.95 ? 163 SER H N 1 ATOM 5972 C CA . SER C 3 163 ? 44.593 61.516 92.812 1.00 31.40 ? 163 SER H CA 1 ATOM 5973 C C . SER C 3 163 ? 44.133 60.755 94.083 1.00 32.09 ? 163 SER H C 1 ATOM 5974 O O . SER C 3 163 ? 44.411 61.119 95.236 1.00 33.33 ? 163 SER H O 1 ATOM 5975 C CB . SER C 3 163 ? 44.866 63.076 92.993 1.00 30.62 ? 163 SER H CB 1 ATOM 5976 O OG . SER C 3 163 ? 44.605 63.909 91.818 1.00 32.04 ? 163 SER H OG 1 ATOM 5977 N N . GLY C 3 164 ? 43.373 59.678 93.877 1.00 32.88 ? 164 GLY H N 1 ATOM 5978 C CA . GLY C 3 164 ? 42.885 58.914 94.989 1.00 32.61 ? 164 GLY H CA 1 ATOM 5979 C C . GLY C 3 164 ? 41.469 59.306 95.360 1.00 31.85 ? 164 GLY H C 1 ATOM 5980 O O . GLY C 3 164 ? 40.691 58.402 95.662 1.00 31.77 ? 164 GLY H O 1 ATOM 5981 N N . SER C 3 165 ? 41.047 60.579 95.337 1.00 30.09 ? 165 SER H N 1 ATOM 5982 C CA . SER C 3 165 ? 39.672 60.994 95.712 1.00 30.64 ? 165 SER H CA 1 ATOM 5983 C C . SER C 3 165 ? 38.490 60.223 95.076 1.00 30.58 ? 165 SER H C 1 ATOM 5984 O O . SER C 3 165 ? 37.389 60.124 95.647 1.00 33.59 ? 165 SER H O 1 ATOM 5985 C CB . SER C 3 165 ? 39.438 62.476 95.378 1.00 29.57 ? 165 SER H CB 1 ATOM 5986 O OG . SER C 3 165 ? 40.527 63.310 95.751 1.00 31.05 ? 165 SER H OG 1 ATOM 5987 N N . LEU C 3 166 ? 38.675 59.638 93.890 1.00 28.21 ? 166 LEU H N 1 ATOM 5988 C CA . LEU C 3 166 ? 37.604 58.946 93.272 1.00 28.50 ? 166 LEU H CA 1 ATOM 5989 C C . LEU C 3 166 ? 38.046 57.539 93.573 1.00 28.94 ? 166 LEU H C 1 ATOM 5990 O O . LEU C 3 166 ? 38.971 56.977 92.990 1.00 29.30 ? 166 LEU H O 1 ATOM 5991 C CB . LEU C 3 166 ? 37.638 59.357 91.845 1.00 27.05 ? 166 LEU H CB 1 ATOM 5992 C CG . LEU C 3 166 ? 36.300 59.550 91.166 1.00 26.05 ? 166 LEU H CG 1 ATOM 5993 C CD1 . LEU C 3 166 ? 35.502 60.673 91.782 1.00 27.03 ? 166 LEU H CD1 1 ATOM 5994 C CD2 . LEU C 3 166 ? 36.569 59.971 89.746 1.00 24.76 ? 166 LEU H CD2 1 ATOM 5995 N N . SER C 3 167 ? 37.497 57.105 94.704 1.00 29.54 ? 167 SER H N 1 ATOM 5996 C CA . SER C 3 167 ? 37.699 55.742 95.162 1.00 30.80 ? 167 SER H CA 1 ATOM 5997 C C . SER C 3 167 ? 36.459 54.872 95.001 1.00 31.35 ? 167 SER H C 1 ATOM 5998 O O . SER C 3 167 ? 36.574 53.671 94.768 1.00 33.24 ? 167 SER H O 1 ATOM 5999 C CB . SER C 3 167 ? 38.108 55.727 96.633 1.00 32.13 ? 167 SER H CB 1 ATOM 6000 O OG . SER C 3 167 ? 38.972 56.805 96.990 1.00 35.30 ? 167 SER H OG 1 ATOM 6001 N N . SER C 3 168 ? 35.238 55.360 95.132 1.00 31.95 ? 168 SER H N 1 ATOM 6002 C CA . SER C 3 168 ? 34.094 54.497 94.881 1.00 32.59 ? 168 SER H CA 1 ATOM 6003 C C . SER C 3 168 ? 33.757 54.666 93.418 1.00 30.32 ? 168 SER H C 1 ATOM 6004 O O . SER C 3 168 ? 34.029 55.696 92.782 1.00 28.12 ? 168 SER H O 1 ATOM 6005 C CB . SER C 3 168 ? 32.870 54.901 95.740 1.00 36.05 ? 168 SER H CB 1 ATOM 6006 O OG . SER C 3 168 ? 33.030 54.798 97.166 1.00 38.97 ? 168 SER H OG 1 ATOM 6007 N N . GLY C 3 169 ? 33.200 53.607 92.863 1.00 28.46 ? 169 GLY H N 1 ATOM 6008 C CA . GLY C 3 169 ? 32.743 53.678 91.466 1.00 26.32 ? 169 GLY H CA 1 ATOM 6009 C C . GLY C 3 169 ? 33.742 53.118 90.446 1.00 23.43 ? 169 GLY H C 1 ATOM 6010 O O . GLY C 3 169 ? 33.459 52.853 89.265 1.00 19.74 ? 169 GLY H O 1 ATOM 6011 N N . VAL C 3 170 ? 34.930 52.889 90.986 1.00 22.15 ? 171 VAL H N 1 ATOM 6012 C CA . VAL C 3 170 ? 36.044 52.415 90.229 1.00 20.98 ? 171 VAL H CA 1 ATOM 6013 C C . VAL C 3 170 ? 36.062 50.895 90.160 1.00 21.09 ? 171 VAL H C 1 ATOM 6014 O O . VAL C 3 170 ? 35.695 50.214 91.122 1.00 22.82 ? 171 VAL H O 1 ATOM 6015 C CB . VAL C 3 170 ? 37.339 52.945 90.882 1.00 19.96 ? 171 VAL H CB 1 ATOM 6016 C CG1 . VAL C 3 170 ? 38.352 53.008 89.740 1.00 20.50 ? 171 VAL H CG1 1 ATOM 6017 C CG2 . VAL C 3 170 ? 37.188 54.312 91.572 1.00 20.31 ? 171 VAL H CG2 1 ATOM 6018 N N . HIS C 3 171 ? 36.451 50.392 88.989 1.00 21.51 ? 172 HIS H N 1 ATOM 6019 C CA . HIS C 3 171 ? 36.752 48.995 88.729 1.00 20.45 ? 172 HIS H CA 1 ATOM 6020 C C . HIS C 3 171 ? 38.008 49.106 87.914 1.00 18.48 ? 172 HIS H C 1 ATOM 6021 O O . HIS C 3 171 ? 37.959 49.717 86.850 1.00 19.04 ? 172 HIS H O 1 ATOM 6022 C CB . HIS C 3 171 ? 35.821 48.271 87.809 1.00 22.99 ? 172 HIS H CB 1 ATOM 6023 C CG . HIS C 3 171 ? 34.450 47.999 88.375 1.00 27.10 ? 172 HIS H CG 1 ATOM 6024 N ND1 . HIS C 3 171 ? 34.092 47.132 89.320 1.00 29.58 ? 172 HIS H ND1 1 ATOM 6025 C CD2 . HIS C 3 171 ? 33.313 48.626 87.928 1.00 28.88 ? 172 HIS H CD2 1 ATOM 6026 C CE1 . HIS C 3 171 ? 32.787 47.214 89.454 1.00 29.56 ? 172 HIS H CE1 1 ATOM 6027 N NE2 . HIS C 3 171 ? 32.327 48.111 88.612 1.00 29.20 ? 172 HIS H NE2 1 ATOM 6028 N N . THR C 3 172 ? 39.151 48.637 88.372 1.00 15.18 ? 173 THR H N 1 ATOM 6029 C CA . THR C 3 172 ? 40.336 48.634 87.533 1.00 14.85 ? 173 THR H CA 1 ATOM 6030 C C . THR C 3 172 ? 40.413 47.172 87.081 1.00 14.69 ? 173 THR H C 1 ATOM 6031 O O . THR C 3 172 ? 40.488 46.265 87.912 1.00 16.09 ? 173 THR H O 1 ATOM 6032 C CB . THR C 3 172 ? 41.552 49.089 88.394 1.00 15.01 ? 173 THR H CB 1 ATOM 6033 O OG1 . THR C 3 172 ? 41.259 50.354 88.984 1.00 15.25 ? 173 THR H OG1 1 ATOM 6034 C CG2 . THR C 3 172 ? 42.768 49.281 87.571 1.00 17.31 ? 173 THR H CG2 1 ATOM 6035 N N . PHE C 3 173 ? 40.284 46.838 85.807 1.00 12.58 ? 174 PHE H N 1 ATOM 6036 C CA . PHE C 3 173 ? 40.370 45.446 85.383 1.00 9.06 ? 174 PHE H CA 1 ATOM 6037 C C . PHE C 3 173 ? 41.803 44.919 85.370 1.00 9.32 ? 174 PHE H C 1 ATOM 6038 O O . PHE C 3 173 ? 42.699 45.666 84.998 1.00 9.60 ? 174 PHE H O 1 ATOM 6039 C CB . PHE C 3 173 ? 39.782 45.334 84.014 1.00 6.48 ? 174 PHE H CB 1 ATOM 6040 C CG . PHE C 3 173 ? 38.319 45.695 84.052 1.00 5.23 ? 174 PHE H CG 1 ATOM 6041 C CD1 . PHE C 3 173 ? 37.417 44.681 84.331 1.00 4.33 ? 174 PHE H CD1 1 ATOM 6042 C CD2 . PHE C 3 173 ? 37.945 47.011 83.862 1.00 4.04 ? 174 PHE H CD2 1 ATOM 6043 C CE1 . PHE C 3 173 ? 36.096 44.974 84.455 1.00 4.91 ? 174 PHE H CE1 1 ATOM 6044 C CE2 . PHE C 3 173 ? 36.613 47.297 83.995 1.00 3.22 ? 174 PHE H CE2 1 ATOM 6045 C CZ . PHE C 3 173 ? 35.707 46.282 84.283 1.00 6.18 ? 174 PHE H CZ 1 ATOM 6046 N N . PRO C 3 174 ? 42.133 43.696 85.748 1.00 9.06 ? 175 PRO H N 1 ATOM 6047 C CA . PRO C 3 174 ? 43.466 43.097 85.581 1.00 9.83 ? 175 PRO H CA 1 ATOM 6048 C C . PRO C 3 174 ? 44.167 43.344 84.234 1.00 12.65 ? 175 PRO H C 1 ATOM 6049 O O . PRO C 3 174 ? 43.566 43.305 83.144 1.00 13.56 ? 175 PRO H O 1 ATOM 6050 C CB . PRO C 3 174 ? 43.226 41.637 85.810 1.00 9.21 ? 175 PRO H CB 1 ATOM 6051 C CG . PRO C 3 174 ? 42.056 41.655 86.750 1.00 9.08 ? 175 PRO H CG 1 ATOM 6052 C CD . PRO C 3 174 ? 41.152 42.703 86.136 1.00 8.62 ? 175 PRO H CD 1 ATOM 6053 N N . ALA C 3 175 ? 45.466 43.633 84.334 1.00 15.52 ? 176 ALA H N 1 ATOM 6054 C CA . ALA C 3 175 ? 46.263 43.838 83.138 1.00 19.03 ? 176 ALA H CA 1 ATOM 6055 C C . ALA C 3 175 ? 46.497 42.466 82.485 1.00 20.01 ? 176 ALA H C 1 ATOM 6056 O O . ALA C 3 175 ? 46.633 41.415 83.138 1.00 19.81 ? 176 ALA H O 1 ATOM 6057 C CB . ALA C 3 175 ? 47.606 44.479 83.503 1.00 20.75 ? 176 ALA H CB 1 ATOM 6058 N N . VAL C 3 176 ? 46.524 42.481 81.152 1.00 22.28 ? 177 VAL H N 1 ATOM 6059 C CA . VAL C 3 176 ? 46.662 41.271 80.352 1.00 25.04 ? 177 VAL H CA 1 ATOM 6060 C C . VAL C 3 176 ? 47.822 41.456 79.353 1.00 27.34 ? 177 VAL H C 1 ATOM 6061 O O . VAL C 3 176 ? 48.045 42.556 78.806 1.00 28.91 ? 177 VAL H O 1 ATOM 6062 C CB . VAL C 3 176 ? 45.241 41.001 79.694 1.00 23.21 ? 177 VAL H CB 1 ATOM 6063 C CG1 . VAL C 3 176 ? 44.724 42.271 79.035 1.00 24.98 ? 177 VAL H CG1 1 ATOM 6064 C CG2 . VAL C 3 176 ? 45.317 39.862 78.671 1.00 24.12 ? 177 VAL H CG2 1 ATOM 6065 N N . LEU C 3 177 ? 48.643 40.405 79.183 1.00 28.19 ? 178 LEU H N 1 ATOM 6066 C CA . LEU C 3 177 ? 49.785 40.471 78.291 1.00 28.09 ? 178 LEU H CA 1 ATOM 6067 C C . LEU C 3 177 ? 49.360 39.998 76.926 1.00 29.18 ? 178 LEU H C 1 ATOM 6068 O O . LEU C 3 177 ? 49.015 38.819 76.789 1.00 28.99 ? 178 LEU H O 1 ATOM 6069 C CB . LEU C 3 177 ? 50.919 39.579 78.773 1.00 27.14 ? 178 LEU H CB 1 ATOM 6070 C CG . LEU C 3 177 ? 52.239 39.662 78.028 1.00 26.55 ? 178 LEU H CG 1 ATOM 6071 C CD1 . LEU C 3 177 ? 53.070 40.875 78.407 1.00 24.74 ? 178 LEU H CD1 1 ATOM 6072 C CD2 . LEU C 3 177 ? 53.032 38.460 78.422 1.00 27.06 ? 178 LEU H CD2 1 ATOM 6073 N N . GLN C 3 178 ? 49.320 40.891 75.938 1.00 32.38 ? 179 GLN H N 1 ATOM 6074 C CA . GLN C 3 178 ? 49.067 40.469 74.570 1.00 35.16 ? 179 GLN H CA 1 ATOM 6075 C C . GLN C 3 178 ? 50.485 40.237 74.018 1.00 32.75 ? 179 GLN H C 1 ATOM 6076 O O . GLN C 3 178 ? 51.214 41.133 73.561 1.00 35.69 ? 179 GLN H O 1 ATOM 6077 C CB . GLN C 3 178 ? 48.298 41.581 73.832 1.00 40.64 ? 179 GLN H CB 1 ATOM 6078 C CG . GLN C 3 178 ? 47.503 41.202 72.547 1.00 46.55 ? 179 GLN H CG 1 ATOM 6079 C CD . GLN C 3 178 ? 46.679 42.365 71.948 1.00 50.46 ? 179 GLN H CD 1 ATOM 6080 O OE1 . GLN C 3 178 ? 46.972 43.539 72.167 1.00 52.14 ? 179 GLN H OE1 1 ATOM 6081 N NE2 . GLN C 3 178 ? 45.591 42.161 71.197 1.00 54.49 ? 179 GLN H NE2 1 ATOM 6082 N N . SER C 3 179 ? 50.945 39.001 74.226 1.00 30.42 ? 180 SER H N 1 ATOM 6083 C CA . SER C 3 179 ? 52.266 38.526 73.826 1.00 27.69 ? 180 SER H CA 1 ATOM 6084 C C . SER C 3 179 ? 53.479 39.299 74.358 1.00 27.56 ? 180 SER H C 1 ATOM 6085 O O . SER C 3 179 ? 54.132 38.804 75.277 1.00 26.47 ? 180 SER H O 1 ATOM 6086 C CB . SER C 3 179 ? 52.313 38.468 72.293 1.00 26.43 ? 180 SER H CB 1 ATOM 6087 O OG . SER C 3 179 ? 51.255 37.639 71.836 1.00 26.23 ? 180 SER H OG 1 ATOM 6088 N N . ASP C 3 180 ? 53.824 40.497 73.877 1.00 29.05 ? 183 ASP H N 1 ATOM 6089 C CA . ASP C 3 180 ? 55.003 41.205 74.347 1.00 29.41 ? 183 ASP H CA 1 ATOM 6090 C C . ASP C 3 180 ? 54.633 42.344 75.328 1.00 30.04 ? 183 ASP H C 1 ATOM 6091 O O . ASP C 3 180 ? 55.510 42.777 76.092 1.00 30.41 ? 183 ASP H O 1 ATOM 6092 C CB . ASP C 3 180 ? 55.731 41.723 73.098 1.00 28.02 ? 183 ASP H CB 1 ATOM 6093 C CG . ASP C 3 180 ? 57.146 42.257 73.296 1.00 26.69 ? 183 ASP H CG 1 ATOM 6094 O OD1 . ASP C 3 180 ? 58.076 41.460 73.429 1.00 25.13 ? 183 ASP H OD1 1 ATOM 6095 O OD2 . ASP C 3 180 ? 57.317 43.475 73.294 1.00 24.99 ? 183 ASP H OD2 1 ATOM 6096 N N . LEU C 3 181 ? 53.371 42.841 75.404 1.00 28.84 ? 184 LEU H N 1 ATOM 6097 C CA . LEU C 3 181 ? 53.053 43.996 76.255 1.00 28.16 ? 184 LEU H CA 1 ATOM 6098 C C . LEU C 3 181 ? 51.669 43.894 76.869 1.00 27.12 ? 184 LEU H C 1 ATOM 6099 O O . LEU C 3 181 ? 50.820 43.098 76.462 1.00 27.75 ? 184 LEU H O 1 ATOM 6100 C CB . LEU C 3 181 ? 53.091 45.325 75.479 1.00 29.36 ? 184 LEU H CB 1 ATOM 6101 C CG . LEU C 3 181 ? 54.178 45.513 74.432 1.00 29.92 ? 184 LEU H CG 1 ATOM 6102 C CD1 . LEU C 3 181 ? 53.473 45.792 73.119 1.00 32.99 ? 184 LEU H CD1 1 ATOM 6103 C CD2 . LEU C 3 181 ? 55.175 46.573 74.841 1.00 29.85 ? 184 LEU H CD2 1 ATOM 6104 N N . TYR C 3 182 ? 51.470 44.779 77.833 1.00 25.34 ? 185 TYR H N 1 ATOM 6105 C CA . TYR C 3 182 ? 50.284 44.866 78.667 1.00 25.85 ? 185 TYR H CA 1 ATOM 6106 C C . TYR C 3 182 ? 49.164 45.856 78.364 1.00 27.46 ? 185 TYR H C 1 ATOM 6107 O O . TYR C 3 182 ? 49.484 47.016 78.073 1.00 30.61 ? 185 TYR H O 1 ATOM 6108 C CB . TYR C 3 182 ? 50.738 45.132 80.088 1.00 23.09 ? 185 TYR H CB 1 ATOM 6109 C CG . TYR C 3 182 ? 51.382 43.939 80.743 1.00 21.31 ? 185 TYR H CG 1 ATOM 6110 C CD1 . TYR C 3 182 ? 50.613 42.825 80.948 1.00 21.06 ? 185 TYR H CD1 1 ATOM 6111 C CD2 . TYR C 3 182 ? 52.705 43.975 81.117 1.00 21.67 ? 185 TYR H CD2 1 ATOM 6112 C CE1 . TYR C 3 182 ? 51.169 41.728 81.536 1.00 19.39 ? 185 TYR H CE1 1 ATOM 6113 C CE2 . TYR C 3 182 ? 53.273 42.869 81.716 1.00 18.55 ? 185 TYR H CE2 1 ATOM 6114 C CZ . TYR C 3 182 ? 52.492 41.752 81.926 1.00 19.49 ? 185 TYR H CZ 1 ATOM 6115 O OH . TYR C 3 182 ? 53.008 40.648 82.605 1.00 19.50 ? 185 TYR H OH 1 ATOM 6116 N N . THR C 3 183 ? 47.883 45.478 78.492 1.00 28.36 ? 186 THR H N 1 ATOM 6117 C CA . THR C 3 183 ? 46.793 46.439 78.354 1.00 30.40 ? 186 THR H CA 1 ATOM 6118 C C . THR C 3 183 ? 45.965 46.407 79.645 1.00 30.20 ? 186 THR H C 1 ATOM 6119 O O . THR C 3 183 ? 45.703 45.331 80.205 1.00 30.40 ? 186 THR H O 1 ATOM 6120 C CB . THR C 3 183 ? 45.877 46.117 77.123 1.00 32.06 ? 186 THR H CB 1 ATOM 6121 O OG1 . THR C 3 183 ? 46.684 45.938 75.945 1.00 33.62 ? 186 THR H OG1 1 ATOM 6122 C CG2 . THR C 3 183 ? 44.939 47.296 76.825 1.00 31.67 ? 186 THR H CG2 1 ATOM 6123 N N . LEU C 3 184 ? 45.611 47.613 80.110 1.00 30.00 ? 187 LEU H N 1 ATOM 6124 C CA . LEU C 3 184 ? 44.917 47.856 81.361 1.00 28.25 ? 187 LEU H CA 1 ATOM 6125 C C . LEU C 3 184 ? 43.764 48.835 81.127 1.00 27.66 ? 187 LEU H C 1 ATOM 6126 O O . LEU C 3 184 ? 43.805 49.597 80.154 1.00 27.89 ? 187 LEU H O 1 ATOM 6127 C CB . LEU C 3 184 ? 45.943 48.419 82.368 1.00 27.79 ? 187 LEU H CB 1 ATOM 6128 C CG . LEU C 3 184 ? 45.582 48.765 83.823 1.00 28.13 ? 187 LEU H CG 1 ATOM 6129 C CD1 . LEU C 3 184 ? 45.026 47.587 84.550 1.00 26.12 ? 187 LEU H CD1 1 ATOM 6130 C CD2 . LEU C 3 184 ? 46.842 49.157 84.562 1.00 29.13 ? 187 LEU H CD2 1 ATOM 6131 N N . SER C 3 185 ? 42.753 48.842 81.995 1.00 25.49 ? 188 SER H N 1 ATOM 6132 C CA . SER C 3 185 ? 41.586 49.705 81.895 1.00 22.80 ? 188 SER H CA 1 ATOM 6133 C C . SER C 3 185 ? 40.862 49.837 83.247 1.00 21.49 ? 188 SER H C 1 ATOM 6134 O O . SER C 3 185 ? 40.843 48.915 84.083 1.00 20.36 ? 188 SER H O 1 ATOM 6135 C CB . SER C 3 185 ? 40.634 49.109 80.859 1.00 22.82 ? 188 SER H CB 1 ATOM 6136 O OG . SER C 3 185 ? 40.470 47.725 81.150 1.00 22.45 ? 188 SER H OG 1 ATOM 6137 N N . SER C 3 186 ? 40.347 51.019 83.561 1.00 21.55 ? 189 SER H N 1 ATOM 6138 C CA . SER C 3 186 ? 39.429 51.100 84.669 1.00 23.96 ? 189 SER H CA 1 ATOM 6139 C C . SER C 3 186 ? 38.320 52.015 84.253 1.00 24.16 ? 189 SER H C 1 ATOM 6140 O O . SER C 3 186 ? 38.469 52.856 83.350 1.00 24.72 ? 189 SER H O 1 ATOM 6141 C CB . SER C 3 186 ? 40.068 51.643 85.929 1.00 26.38 ? 189 SER H CB 1 ATOM 6142 O OG . SER C 3 186 ? 40.774 52.838 85.728 1.00 28.11 ? 189 SER H OG 1 ATOM 6143 N N . SER C 3 187 ? 37.186 51.727 84.866 1.00 24.42 ? 190 SER H N 1 ATOM 6144 C CA . SER C 3 187 ? 35.990 52.517 84.657 1.00 22.92 ? 190 SER H CA 1 ATOM 6145 C C . SER C 3 187 ? 35.764 53.286 85.942 1.00 21.85 ? 190 SER H C 1 ATOM 6146 O O . SER C 3 187 ? 36.363 52.941 86.965 1.00 20.04 ? 190 SER H O 1 ATOM 6147 C CB . SER C 3 187 ? 34.769 51.603 84.357 1.00 22.99 ? 190 SER H CB 1 ATOM 6148 O OG . SER C 3 187 ? 34.279 50.635 85.298 1.00 26.36 ? 190 SER H OG 1 ATOM 6149 N N . VAL C 3 188 ? 34.995 54.359 85.903 1.00 21.18 ? 191 VAL H N 1 ATOM 6150 C CA . VAL C 3 188 ? 34.529 54.983 87.101 1.00 21.34 ? 191 VAL H CA 1 ATOM 6151 C C . VAL C 3 188 ? 33.193 55.551 86.678 1.00 21.16 ? 191 VAL H C 1 ATOM 6152 O O . VAL C 3 188 ? 32.980 55.949 85.535 1.00 22.29 ? 191 VAL H O 1 ATOM 6153 C CB . VAL C 3 188 ? 35.523 56.055 87.597 1.00 20.03 ? 191 VAL H CB 1 ATOM 6154 C CG1 . VAL C 3 188 ? 35.687 57.226 86.661 1.00 19.69 ? 191 VAL H CG1 1 ATOM 6155 C CG2 . VAL C 3 188 ? 35.024 56.461 88.972 1.00 18.69 ? 191 VAL H CG2 1 ATOM 6156 N N . THR C 3 189 ? 32.258 55.440 87.601 1.00 20.68 ? 192 THR H N 1 ATOM 6157 C CA . THR C 3 189 ? 30.890 55.851 87.420 1.00 19.16 ? 192 THR H CA 1 ATOM 6158 C C . THR C 3 189 ? 30.704 57.021 88.377 1.00 19.52 ? 192 THR H C 1 ATOM 6159 O O . THR C 3 189 ? 31.069 56.879 89.554 1.00 17.14 ? 192 THR H O 1 ATOM 6160 C CB . THR C 3 189 ? 30.055 54.644 87.782 1.00 19.30 ? 192 THR H CB 1 ATOM 6161 O OG1 . THR C 3 189 ? 30.554 53.542 87.011 1.00 19.68 ? 192 THR H OG1 1 ATOM 6162 C CG2 . THR C 3 189 ? 28.581 54.910 87.547 1.00 17.66 ? 192 THR H CG2 1 ATOM 6163 N N . VAL C 3 190 ? 30.209 58.168 87.911 1.00 20.00 ? 193 VAL H N 1 ATOM 6164 C CA . VAL C 3 190 ? 29.965 59.330 88.741 1.00 20.77 ? 193 VAL H CA 1 ATOM 6165 C C . VAL C 3 190 ? 28.597 59.809 88.356 1.00 21.74 ? 193 VAL H C 1 ATOM 6166 O O . VAL C 3 190 ? 28.046 59.475 87.304 1.00 21.98 ? 193 VAL H O 1 ATOM 6167 C CB . VAL C 3 190 ? 30.895 60.575 88.538 1.00 19.21 ? 193 VAL H CB 1 ATOM 6168 C CG1 . VAL C 3 190 ? 32.232 60.249 89.126 1.00 18.99 ? 193 VAL H CG1 1 ATOM 6169 C CG2 . VAL C 3 190 ? 31.083 60.961 87.077 1.00 20.54 ? 193 VAL H CG2 1 ATOM 6170 N N . THR C 3 191 ? 28.041 60.600 89.248 1.00 21.31 ? 194 THR H N 1 ATOM 6171 C CA . THR C 3 191 ? 26.756 61.186 88.992 1.00 20.22 ? 194 THR H CA 1 ATOM 6172 C C . THR C 3 191 ? 26.987 62.306 88.018 1.00 21.21 ? 194 THR H C 1 ATOM 6173 O O . THR C 3 191 ? 28.043 62.940 87.944 1.00 20.87 ? 194 THR H O 1 ATOM 6174 C CB . THR C 3 191 ? 26.153 61.665 90.333 1.00 19.55 ? 194 THR H CB 1 ATOM 6175 O OG1 . THR C 3 191 ? 27.209 62.023 91.224 1.00 21.01 ? 194 THR H OG1 1 ATOM 6176 C CG2 . THR C 3 191 ? 25.325 60.539 90.969 1.00 17.93 ? 194 THR H CG2 1 ATOM 6177 N N . SER C 3 192 ? 25.915 62.534 87.316 1.00 23.84 ? 195 SER H N 1 ATOM 6178 C CA . SER C 3 192 ? 25.869 63.560 86.314 1.00 26.98 ? 195 SER H CA 1 ATOM 6179 C C . SER C 3 192 ? 26.227 64.942 86.859 1.00 26.80 ? 195 SER H C 1 ATOM 6180 O O . SER C 3 192 ? 26.861 65.760 86.192 1.00 28.63 ? 195 SER H O 1 ATOM 6181 C CB . SER C 3 192 ? 24.475 63.456 85.776 1.00 30.45 ? 195 SER H CB 1 ATOM 6182 O OG . SER C 3 192 ? 24.141 62.070 85.598 1.00 35.69 ? 195 SER H OG 1 ATOM 6183 N N . SER C 3 193 ? 25.915 65.242 88.117 1.00 25.89 ? 196 SER H N 1 ATOM 6184 C CA . SER C 3 193 ? 26.220 66.563 88.664 1.00 24.90 ? 196 SER H CA 1 ATOM 6185 C C . SER C 3 193 ? 27.741 66.841 88.700 1.00 25.56 ? 196 SER H C 1 ATOM 6186 O O . SER C 3 193 ? 28.267 67.936 88.430 1.00 24.79 ? 196 SER H O 1 ATOM 6187 C CB . SER C 3 193 ? 25.579 66.600 90.045 1.00 25.40 ? 196 SER H CB 1 ATOM 6188 O OG . SER C 3 193 ? 24.342 65.886 89.994 1.00 25.29 ? 196 SER H OG 1 ATOM 6189 N N . THR C 3 194 ? 28.429 65.729 88.971 1.00 25.58 ? 198 THR H N 1 ATOM 6190 C CA . THR C 3 194 ? 29.864 65.675 89.132 1.00 26.40 ? 198 THR H CA 1 ATOM 6191 C C . THR C 3 194 ? 30.596 65.872 87.824 1.00 26.15 ? 198 THR H C 1 ATOM 6192 O O . THR C 3 194 ? 31.681 66.437 87.864 1.00 26.95 ? 198 THR H O 1 ATOM 6193 C CB . THR C 3 194 ? 30.258 64.315 89.731 1.00 27.20 ? 198 THR H CB 1 ATOM 6194 O OG1 . THR C 3 194 ? 29.148 63.972 90.555 1.00 30.38 ? 198 THR H OG1 1 ATOM 6195 C CG2 . THR C 3 194 ? 31.565 64.307 90.523 1.00 27.78 ? 198 THR H CG2 1 ATOM 6196 N N . TRP C 3 195 ? 30.090 65.489 86.659 1.00 23.38 ? 199 TRP H N 1 ATOM 6197 C CA . TRP C 3 195 ? 30.900 65.529 85.465 1.00 20.78 ? 199 TRP H CA 1 ATOM 6198 C C . TRP C 3 195 ? 29.975 65.941 84.330 1.00 20.73 ? 199 TRP H C 1 ATOM 6199 O O . TRP C 3 195 ? 28.864 65.422 84.246 1.00 20.18 ? 199 TRP H O 1 ATOM 6200 C CB . TRP C 3 195 ? 31.559 64.109 85.223 1.00 18.03 ? 199 TRP H CB 1 ATOM 6201 C CG . TRP C 3 195 ? 32.541 64.128 84.028 1.00 15.55 ? 199 TRP H CG 1 ATOM 6202 C CD1 . TRP C 3 195 ? 33.849 64.562 84.144 1.00 15.02 ? 199 TRP H CD1 1 ATOM 6203 C CD2 . TRP C 3 195 ? 32.192 63.935 82.705 1.00 14.68 ? 199 TRP H CD2 1 ATOM 6204 N NE1 . TRP C 3 195 ? 34.297 64.672 82.921 1.00 14.63 ? 199 TRP H NE1 1 ATOM 6205 C CE2 . TRP C 3 195 ? 33.349 64.310 82.041 1.00 14.73 ? 199 TRP H CE2 1 ATOM 6206 C CE3 . TRP C 3 195 ? 31.069 63.522 82.014 1.00 14.88 ? 199 TRP H CE3 1 ATOM 6207 C CZ2 . TRP C 3 195 ? 33.387 64.298 80.664 1.00 14.71 ? 199 TRP H CZ2 1 ATOM 6208 C CZ3 . TRP C 3 195 ? 31.113 63.516 80.634 1.00 14.86 ? 199 TRP H CZ3 1 ATOM 6209 C CH2 . TRP C 3 195 ? 32.263 63.890 79.964 1.00 14.32 ? 199 TRP H CH2 1 ATOM 6210 N N . PRO C 3 196 ? 30.337 66.800 83.362 1.00 22.03 ? 200 PRO H N 1 ATOM 6211 C CA . PRO C 3 196 ? 31.672 67.387 83.150 1.00 21.58 ? 200 PRO H CA 1 ATOM 6212 C C . PRO C 3 196 ? 32.058 68.586 84.008 1.00 21.75 ? 200 PRO H C 1 ATOM 6213 O O . PRO C 3 196 ? 32.990 69.326 83.710 1.00 20.77 ? 200 PRO H O 1 ATOM 6214 C CB . PRO C 3 196 ? 31.701 67.724 81.671 1.00 21.35 ? 200 PRO H CB 1 ATOM 6215 C CG . PRO C 3 196 ? 30.473 67.054 81.098 1.00 22.74 ? 200 PRO H CG 1 ATOM 6216 C CD . PRO C 3 196 ? 29.473 67.123 82.229 1.00 22.79 ? 200 PRO H CD 1 ATOM 6217 N N . SER C 3 197 ? 31.294 68.801 85.061 1.00 24.21 ? 202 SER H N 1 ATOM 6218 C CA . SER C 3 197 ? 31.427 69.929 85.954 1.00 27.73 ? 202 SER H CA 1 ATOM 6219 C C . SER C 3 197 ? 32.695 69.839 86.827 1.00 29.43 ? 202 SER H C 1 ATOM 6220 O O . SER C 3 197 ? 33.517 70.748 86.829 1.00 29.49 ? 202 SER H O 1 ATOM 6221 C CB . SER C 3 197 ? 30.092 69.902 86.701 1.00 28.61 ? 202 SER H CB 1 ATOM 6222 O OG . SER C 3 197 ? 29.043 69.331 85.875 1.00 29.76 ? 202 SER H OG 1 ATOM 6223 N N . GLN C 3 198 ? 32.929 68.801 87.624 1.00 30.79 ? 203 GLN H N 1 ATOM 6224 C CA . GLN C 3 198 ? 34.183 68.660 88.345 1.00 31.75 ? 203 GLN H CA 1 ATOM 6225 C C . GLN C 3 198 ? 35.179 68.059 87.346 1.00 32.27 ? 203 GLN H C 1 ATOM 6226 O O . GLN C 3 198 ? 34.819 67.465 86.319 1.00 32.15 ? 203 GLN H O 1 ATOM 6227 C CB . GLN C 3 198 ? 34.049 67.715 89.528 1.00 31.99 ? 203 GLN H CB 1 ATOM 6228 C CG . GLN C 3 198 ? 33.220 68.298 90.656 1.00 31.64 ? 203 GLN H CG 1 ATOM 6229 C CD . GLN C 3 198 ? 33.835 69.544 91.268 1.00 31.66 ? 203 GLN H CD 1 ATOM 6230 O OE1 . GLN C 3 198 ? 34.919 69.515 91.838 1.00 30.73 ? 203 GLN H OE1 1 ATOM 6231 N NE2 . GLN C 3 198 ? 33.178 70.687 91.177 1.00 32.27 ? 203 GLN H NE2 1 ATOM 6232 N N . SER C 3 199 ? 36.456 68.100 87.667 1.00 32.87 ? 204 SER H N 1 ATOM 6233 C CA . SER C 3 199 ? 37.502 67.715 86.743 1.00 34.33 ? 204 SER H CA 1 ATOM 6234 C C . SER C 3 199 ? 38.008 66.293 86.899 1.00 33.18 ? 204 SER H C 1 ATOM 6235 O O . SER C 3 199 ? 38.982 66.054 87.619 1.00 34.68 ? 204 SER H O 1 ATOM 6236 C CB . SER C 3 199 ? 38.584 68.770 86.941 1.00 36.50 ? 204 SER H CB 1 ATOM 6237 O OG . SER C 3 199 ? 38.611 69.250 88.306 1.00 39.11 ? 204 SER H OG 1 ATOM 6238 N N . ILE C 3 200 ? 37.355 65.323 86.263 1.00 31.87 ? 205 ILE H N 1 ATOM 6239 C CA . ILE C 3 200 ? 37.817 63.938 86.373 1.00 28.03 ? 205 ILE H CA 1 ATOM 6240 C C . ILE C 3 200 ? 39.125 63.724 85.607 1.00 26.80 ? 205 ILE H C 1 ATOM 6241 O O . ILE C 3 200 ? 39.323 64.201 84.473 1.00 28.45 ? 205 ILE H O 1 ATOM 6242 C CB . ILE C 3 200 ? 36.721 62.937 85.861 1.00 26.61 ? 205 ILE H CB 1 ATOM 6243 C CG1 . ILE C 3 200 ? 35.410 63.137 86.630 1.00 25.23 ? 205 ILE H CG1 1 ATOM 6244 C CG2 . ILE C 3 200 ? 37.176 61.482 86.072 1.00 25.89 ? 205 ILE H CG2 1 ATOM 6245 C CD1 . ILE C 3 200 ? 35.511 63.361 88.155 1.00 25.14 ? 205 ILE H CD1 1 ATOM 6246 N N . THR C 3 201 ? 40.001 62.982 86.287 1.00 25.88 ? 206 THR H N 1 ATOM 6247 C CA . THR C 3 201 ? 41.343 62.663 85.866 1.00 26.00 ? 206 THR H CA 1 ATOM 6248 C C . THR C 3 201 ? 41.801 61.251 86.265 1.00 25.26 ? 206 THR H C 1 ATOM 6249 O O . THR C 3 201 ? 41.445 60.656 87.296 1.00 25.38 ? 206 THR H O 1 ATOM 6250 C CB . THR C 3 201 ? 42.251 63.792 86.437 1.00 26.15 ? 206 THR H CB 1 ATOM 6251 O OG1 . THR C 3 201 ? 42.062 64.849 85.502 1.00 24.31 ? 206 THR H OG1 1 ATOM 6252 C CG2 . THR C 3 201 ? 43.754 63.469 86.604 1.00 26.77 ? 206 THR H CG2 1 ATOM 6253 N N . CYS C 3 202 ? 42.601 60.760 85.320 1.00 24.52 ? 208 CYS H N 1 ATOM 6254 C CA . CYS C 3 202 ? 43.253 59.479 85.401 1.00 25.29 ? 208 CYS H CA 1 ATOM 6255 C C . CYS C 3 202 ? 44.732 59.725 85.700 1.00 25.37 ? 208 CYS H C 1 ATOM 6256 O O . CYS C 3 202 ? 45.389 60.421 84.926 1.00 27.76 ? 208 CYS H O 1 ATOM 6257 C CB . CYS C 3 202 ? 43.038 58.787 84.057 1.00 24.20 ? 208 CYS H CB 1 ATOM 6258 S SG . CYS C 3 202 ? 43.387 57.005 84.172 1.00 24.79 ? 208 CYS H SG 1 ATOM 6259 N N . ASN C 3 203 ? 45.341 59.273 86.786 1.00 26.24 ? 209 ASN H N 1 ATOM 6260 C CA . ASN C 3 203 ? 46.769 59.479 86.978 1.00 25.58 ? 209 ASN H CA 1 ATOM 6261 C C . ASN C 3 203 ? 47.336 58.082 86.832 1.00 26.12 ? 209 ASN H C 1 ATOM 6262 O O . ASN C 3 203 ? 46.880 57.174 87.544 1.00 26.10 ? 209 ASN H O 1 ATOM 6263 C CB . ASN C 3 203 ? 47.129 59.982 88.370 1.00 26.99 ? 209 ASN H CB 1 ATOM 6264 C CG . ASN C 3 203 ? 46.111 60.890 89.059 1.00 28.99 ? 209 ASN H CG 1 ATOM 6265 O OD1 . ASN C 3 203 ? 45.011 60.463 89.432 1.00 32.06 ? 209 ASN H OD1 1 ATOM 6266 N ND2 . ASN C 3 203 ? 46.370 62.157 89.361 1.00 29.66 ? 209 ASN H ND2 1 ATOM 6267 N N . VAL C 3 204 ? 48.301 57.877 85.929 1.00 27.55 ? 210 VAL H N 1 ATOM 6268 C CA . VAL C 3 204 ? 48.888 56.572 85.661 1.00 30.03 ? 210 VAL H CA 1 ATOM 6269 C C . VAL C 3 204 ? 50.401 56.632 85.855 1.00 31.98 ? 210 VAL H C 1 ATOM 6270 O O . VAL C 3 204 ? 51.068 57.471 85.235 1.00 33.41 ? 210 VAL H O 1 ATOM 6271 C CB . VAL C 3 204 ? 48.536 56.141 84.212 1.00 29.60 ? 210 VAL H CB 1 ATOM 6272 C CG1 . VAL C 3 204 ? 49.413 55.037 83.606 1.00 28.62 ? 210 VAL H CG1 1 ATOM 6273 C CG2 . VAL C 3 204 ? 47.118 55.623 84.309 1.00 29.58 ? 210 VAL H CG2 1 ATOM 6274 N N . ALA C 3 205 ? 50.935 55.796 86.760 1.00 31.35 ? 211 ALA H N 1 ATOM 6275 C CA . ALA C 3 205 ? 52.380 55.668 86.970 1.00 29.83 ? 211 ALA H CA 1 ATOM 6276 C C . ALA C 3 205 ? 52.943 54.301 86.594 1.00 27.90 ? 211 ALA H C 1 ATOM 6277 O O . ALA C 3 205 ? 52.478 53.254 87.076 1.00 28.50 ? 211 ALA H O 1 ATOM 6278 C CB . ALA C 3 205 ? 52.775 55.876 88.417 1.00 29.95 ? 211 ALA H CB 1 ATOM 6279 N N . HIS C 3 206 ? 53.923 54.309 85.690 1.00 26.95 ? 212 HIS H N 1 ATOM 6280 C CA . HIS C 3 206 ? 54.622 53.112 85.275 1.00 27.96 ? 212 HIS H CA 1 ATOM 6281 C C . HIS C 3 206 ? 56.043 53.394 85.701 1.00 30.04 ? 212 HIS H C 1 ATOM 6282 O O . HIS C 3 206 ? 56.794 54.086 85.012 1.00 29.75 ? 212 HIS H O 1 ATOM 6283 C CB . HIS C 3 206 ? 54.605 52.891 83.783 1.00 25.41 ? 212 HIS H CB 1 ATOM 6284 C CG . HIS C 3 206 ? 55.311 51.603 83.361 1.00 23.32 ? 212 HIS H CG 1 ATOM 6285 N ND1 . HIS C 3 206 ? 56.002 51.386 82.243 1.00 23.08 ? 212 HIS H ND1 1 ATOM 6286 C CD2 . HIS C 3 206 ? 55.372 50.430 84.084 1.00 24.54 ? 212 HIS H CD2 1 ATOM 6287 C CE1 . HIS C 3 206 ? 56.477 50.160 82.252 1.00 22.33 ? 212 HIS H CE1 1 ATOM 6288 N NE2 . HIS C 3 206 ? 56.090 49.595 83.369 1.00 23.91 ? 212 HIS H NE2 1 ATOM 6289 N N . PRO C 3 207 ? 56.462 52.900 86.872 1.00 32.70 ? 213 PRO H N 1 ATOM 6290 C CA . PRO C 3 207 ? 57.733 53.274 87.476 1.00 33.64 ? 213 PRO H CA 1 ATOM 6291 C C . PRO C 3 207 ? 58.929 52.612 86.803 1.00 34.99 ? 213 PRO H C 1 ATOM 6292 O O . PRO C 3 207 ? 60.060 53.072 86.937 1.00 34.94 ? 213 PRO H O 1 ATOM 6293 C CB . PRO C 3 207 ? 57.545 52.907 88.935 1.00 34.22 ? 213 PRO H CB 1 ATOM 6294 C CG . PRO C 3 207 ? 56.682 51.659 88.860 1.00 34.14 ? 213 PRO H CG 1 ATOM 6295 C CD . PRO C 3 207 ? 55.701 51.987 87.743 1.00 33.68 ? 213 PRO H CD 1 ATOM 6296 N N . ALA C 3 208 ? 58.691 51.520 86.087 1.00 35.17 ? 214 ALA H N 1 ATOM 6297 C CA . ALA C 3 208 ? 59.749 50.915 85.317 1.00 35.44 ? 214 ALA H CA 1 ATOM 6298 C C . ALA C 3 208 ? 60.329 51.901 84.312 1.00 35.39 ? 214 ALA H C 1 ATOM 6299 O O . ALA C 3 208 ? 61.543 52.067 84.234 1.00 33.72 ? 214 ALA H O 1 ATOM 6300 C CB . ALA C 3 208 ? 59.215 49.735 84.556 1.00 37.33 ? 214 ALA H CB 1 ATOM 6301 N N . SER C 3 209 ? 59.484 52.562 83.517 1.00 36.27 ? 215 SER H N 1 ATOM 6302 C CA . SER C 3 209 ? 59.990 53.553 82.581 1.00 36.15 ? 215 SER H CA 1 ATOM 6303 C C . SER C 3 209 ? 60.432 54.858 83.230 1.00 38.11 ? 215 SER H C 1 ATOM 6304 O O . SER C 3 209 ? 61.402 55.485 82.782 1.00 40.80 ? 215 SER H O 1 ATOM 6305 C CB . SER C 3 209 ? 58.932 53.856 81.549 1.00 34.78 ? 215 SER H CB 1 ATOM 6306 O OG . SER C 3 209 ? 57.639 53.804 82.126 1.00 31.68 ? 215 SER H OG 1 ATOM 6307 N N . SER C 3 210 ? 59.676 55.159 84.303 1.00 39.00 ? 216 SER H N 1 ATOM 6308 C CA . SER C 3 210 ? 59.716 56.332 85.178 1.00 39.06 ? 216 SER H CA 1 ATOM 6309 C C . SER C 3 210 ? 58.701 57.245 84.505 1.00 39.08 ? 216 SER H C 1 ATOM 6310 O O . SER C 3 210 ? 58.993 58.306 83.935 1.00 40.99 ? 216 SER H O 1 ATOM 6311 C CB . SER C 3 210 ? 61.101 57.038 85.227 1.00 38.95 ? 216 SER H CB 1 ATOM 6312 O OG . SER C 3 210 ? 62.164 56.179 85.636 1.00 42.23 ? 216 SER H OG 1 ATOM 6313 N N . THR C 3 211 ? 57.453 56.783 84.517 1.00 38.72 ? 217 THR H N 1 ATOM 6314 C CA . THR C 3 211 ? 56.391 57.493 83.841 1.00 37.91 ? 217 THR H CA 1 ATOM 6315 C C . THR C 3 211 ? 55.285 57.857 84.799 1.00 38.09 ? 217 THR H C 1 ATOM 6316 O O . THR C 3 211 ? 54.875 56.985 85.572 1.00 37.56 ? 217 THR H O 1 ATOM 6317 C CB . THR C 3 211 ? 55.900 56.582 82.702 1.00 37.86 ? 217 THR H CB 1 ATOM 6318 O OG1 . THR C 3 211 ? 57.068 56.294 81.912 1.00 38.33 ? 217 THR H OG1 1 ATOM 6319 C CG2 . THR C 3 211 ? 54.778 57.204 81.859 1.00 37.25 ? 217 THR H CG2 1 ATOM 6320 N N . LYS C 3 212 ? 54.882 59.137 84.792 1.00 38.91 ? 218 LYS H N 1 ATOM 6321 C CA . LYS C 3 212 ? 53.736 59.634 85.558 1.00 38.71 ? 218 LYS H CA 1 ATOM 6322 C C . LYS C 3 212 ? 52.871 60.457 84.614 1.00 37.75 ? 218 LYS H C 1 ATOM 6323 O O . LYS C 3 212 ? 53.303 61.505 84.154 1.00 38.05 ? 218 LYS H O 1 ATOM 6324 C CB . LYS C 3 212 ? 54.158 60.523 86.744 1.00 39.34 ? 218 LYS H CB 1 ATOM 6325 C CG . LYS C 3 212 ? 54.560 59.762 88.036 1.00 41.52 ? 218 LYS H CG 1 ATOM 6326 C CD . LYS C 3 212 ? 55.931 59.067 87.930 1.00 44.03 ? 218 LYS H CD 1 ATOM 6327 C CE . LYS C 3 212 ? 56.072 57.872 88.888 1.00 45.88 ? 218 LYS H CE 1 ATOM 6328 N NZ . LYS C 3 212 ? 56.778 56.761 88.255 1.00 46.17 ? 218 LYS H NZ 1 ATOM 6329 N N . VAL C 3 213 ? 51.657 60.001 84.310 1.00 35.99 ? 219 VAL H N 1 ATOM 6330 C CA . VAL C 3 213 ? 50.749 60.545 83.300 1.00 34.31 ? 219 VAL H CA 1 ATOM 6331 C C . VAL C 3 213 ? 49.494 61.000 84.014 1.00 32.53 ? 219 VAL H C 1 ATOM 6332 O O . VAL C 3 213 ? 49.155 60.364 85.019 1.00 32.09 ? 219 VAL H O 1 ATOM 6333 C CB . VAL C 3 213 ? 50.420 59.426 82.294 1.00 34.86 ? 219 VAL H CB 1 ATOM 6334 C CG1 . VAL C 3 213 ? 49.242 59.766 81.394 1.00 33.28 ? 219 VAL H CG1 1 ATOM 6335 C CG2 . VAL C 3 213 ? 51.661 59.209 81.457 1.00 36.45 ? 219 VAL H CG2 1 ATOM 6336 N N . ASP C 3 214 ? 48.819 62.059 83.543 1.00 31.98 ? 220 ASP H N 1 ATOM 6337 C CA . ASP C 3 214 ? 47.575 62.562 84.128 1.00 30.99 ? 220 ASP H CA 1 ATOM 6338 C C . ASP C 3 214 ? 46.637 62.964 82.996 1.00 29.53 ? 220 ASP H C 1 ATOM 6339 O O . ASP C 3 214 ? 46.870 63.978 82.325 1.00 30.32 ? 220 ASP H O 1 ATOM 6340 C CB . ASP C 3 214 ? 47.819 63.795 84.993 1.00 32.44 ? 220 ASP H CB 1 ATOM 6341 C CG . ASP C 3 214 ? 48.260 63.560 86.438 1.00 34.10 ? 220 ASP H CG 1 ATOM 6342 O OD1 . ASP C 3 214 ? 49.418 63.193 86.682 1.00 35.42 ? 220 ASP H OD1 1 ATOM 6343 O OD2 . ASP C 3 214 ? 47.434 63.778 87.333 1.00 37.69 ? 220 ASP H OD2 1 ATOM 6344 N N . LYS C 3 215 ? 45.590 62.200 82.706 1.00 29.21 ? 221 LYS H N 1 ATOM 6345 C CA . LYS C 3 215 ? 44.695 62.481 81.590 1.00 27.95 ? 221 LYS H CA 1 ATOM 6346 C C . LYS C 3 215 ? 43.365 63.039 82.002 1.00 27.08 ? 221 LYS H C 1 ATOM 6347 O O . LYS C 3 215 ? 42.688 62.391 82.802 1.00 28.42 ? 221 LYS H O 1 ATOM 6348 C CB . LYS C 3 215 ? 44.395 61.236 80.766 1.00 29.18 ? 221 LYS H CB 1 ATOM 6349 C CG . LYS C 3 215 ? 45.581 60.790 79.943 1.00 31.91 ? 221 LYS H CG 1 ATOM 6350 C CD . LYS C 3 215 ? 46.165 61.964 79.179 1.00 34.80 ? 221 LYS H CD 1 ATOM 6351 C CE . LYS C 3 215 ? 45.178 62.518 78.172 1.00 37.52 ? 221 LYS H CE 1 ATOM 6352 N NZ . LYS C 3 215 ? 45.019 61.576 77.087 1.00 38.50 ? 221 LYS H NZ 1 ATOM 6353 N N . LYS C 3 216 ? 42.968 64.220 81.517 1.00 26.49 ? 222 LYS H N 1 ATOM 6354 C CA . LYS C 3 216 ? 41.643 64.732 81.837 1.00 25.26 ? 222 LYS H CA 1 ATOM 6355 C C . LYS C 3 216 ? 40.664 63.980 80.950 1.00 25.74 ? 222 LYS H C 1 ATOM 6356 O O . LYS C 3 216 ? 40.934 63.748 79.761 1.00 28.24 ? 222 LYS H O 1 ATOM 6357 C CB . LYS C 3 216 ? 41.532 66.218 81.554 1.00 23.48 ? 222 LYS H CB 1 ATOM 6358 C CG . LYS C 3 216 ? 41.906 67.043 82.774 1.00 22.74 ? 222 LYS H CG 1 ATOM 6359 C CD . LYS C 3 216 ? 41.498 68.481 82.523 1.00 22.53 ? 222 LYS H CD 1 ATOM 6360 C CE . LYS C 3 216 ? 41.571 69.298 83.799 1.00 22.57 ? 222 LYS H CE 1 ATOM 6361 N NZ . LYS C 3 216 ? 41.145 70.653 83.523 1.00 22.21 ? 222 LYS H NZ 1 ATOM 6362 N N . ILE C 3 217 ? 39.555 63.484 81.486 1.00 26.16 ? 223 ILE H N 1 ATOM 6363 C CA . ILE C 3 217 ? 38.593 62.821 80.628 1.00 26.32 ? 223 ILE H CA 1 ATOM 6364 C C . ILE C 3 217 ? 37.629 63.993 80.501 1.00 29.07 ? 223 ILE H C 1 ATOM 6365 O O . ILE C 3 217 ? 36.837 64.319 81.401 1.00 30.38 ? 223 ILE H O 1 ATOM 6366 C CB . ILE C 3 217 ? 37.994 61.566 81.337 1.00 23.74 ? 223 ILE H CB 1 ATOM 6367 C CG1 . ILE C 3 217 ? 38.998 60.428 81.479 1.00 22.55 ? 223 ILE H CG1 1 ATOM 6368 C CG2 . ILE C 3 217 ? 36.915 60.978 80.445 1.00 23.30 ? 223 ILE H CG2 1 ATOM 6369 C CD1 . ILE C 3 217 ? 40.242 60.633 82.340 1.00 23.58 ? 223 ILE H CD1 1 ATOM 6370 N N . GLU C 3 218 ? 37.929 64.713 79.405 1.00 31.78 ? 224 GLU H N 1 ATOM 6371 C CA . GLU C 3 218 ? 37.257 65.940 78.987 1.00 32.19 ? 224 GLU H CA 1 ATOM 6372 C C . GLU C 3 218 ? 36.217 65.528 77.952 1.00 34.83 ? 224 GLU H C 1 ATOM 6373 O O . GLU C 3 218 ? 36.507 64.603 77.197 1.00 33.54 ? 224 GLU H O 1 ATOM 6374 C CB . GLU C 3 218 ? 38.389 66.849 78.466 1.00 30.67 ? 224 GLU H CB 1 ATOM 6375 C CG . GLU C 3 218 ? 38.157 68.020 77.512 1.00 27.05 ? 224 GLU H CG 1 ATOM 6376 C CD . GLU C 3 218 ? 38.166 67.635 76.037 1.00 25.18 ? 224 GLU H CD 1 ATOM 6377 O OE1 . GLU C 3 218 ? 39.243 67.635 75.438 1.00 23.40 ? 224 GLU H OE1 1 ATOM 6378 O OE2 . GLU C 3 218 ? 37.111 67.336 75.484 1.00 23.26 ? 224 GLU H OE2 1 ATOM 6379 N N . PRO C 3 219 ? 35.027 66.120 77.777 1.00 36.56 ? 225 PRO H N 1 ATOM 6380 C CA . PRO C 3 219 ? 33.839 65.439 77.295 1.00 40.19 ? 225 PRO H CA 1 ATOM 6381 C C . PRO C 3 219 ? 33.742 64.915 75.882 1.00 41.71 ? 225 PRO H C 1 ATOM 6382 O O . PRO C 3 219 ? 32.691 64.350 75.609 1.00 46.04 ? 225 PRO H O 1 ATOM 6383 C CB . PRO C 3 219 ? 32.726 66.423 77.595 1.00 39.96 ? 225 PRO H CB 1 ATOM 6384 C CG . PRO C 3 219 ? 33.404 67.724 77.272 1.00 42.00 ? 225 PRO H CG 1 ATOM 6385 C CD . PRO C 3 219 ? 34.721 67.524 78.012 1.00 40.47 ? 225 PRO H CD 1 ATOM 6386 N N . ARG C 3 220 ? 34.760 64.999 75.018 1.00 39.95 ? 226 ARG H N 1 ATOM 6387 C CA . ARG C 3 220 ? 34.670 64.653 73.591 1.00 39.90 ? 226 ARG H CA 1 ATOM 6388 C C . ARG C 3 220 ? 33.571 63.748 72.975 1.00 41.35 ? 226 ARG H C 1 ATOM 6389 O O . ARG C 3 220 ? 33.723 62.561 72.619 1.00 42.95 ? 226 ARG H O 1 ATOM 6390 C CB . ARG C 3 220 ? 36.051 64.104 73.172 1.00 38.14 ? 226 ARG H CB 1 ATOM 6391 C CG . ARG C 3 220 ? 36.533 62.865 73.918 1.00 40.23 ? 226 ARG H CG 1 ATOM 6392 C CD . ARG C 3 220 ? 37.727 62.215 73.238 1.00 40.78 ? 226 ARG H CD 1 ATOM 6393 N NE . ARG C 3 220 ? 37.500 60.783 73.113 1.00 39.39 ? 226 ARG H NE 1 ATOM 6394 C CZ . ARG C 3 220 ? 36.964 60.240 72.013 1.00 37.13 ? 226 ARG H CZ 1 ATOM 6395 N NH1 . ARG C 3 220 ? 36.661 60.968 70.936 1.00 35.96 ? 226 ARG H NH1 1 ATOM 6396 N NH2 . ARG C 3 220 ? 36.755 58.929 71.980 1.00 35.67 ? 226 ARG H NH2 1 ATOM 6397 N N . GLY C 3 221 ? 32.470 64.476 72.832 1.00 40.92 ? 227 GLY H N 1 ATOM 6398 C CA . GLY C 3 221 ? 31.232 64.073 72.200 1.00 40.13 ? 227 GLY H CA 1 ATOM 6399 C C . GLY C 3 221 ? 30.499 65.349 71.768 1.00 39.50 ? 227 GLY H C 1 ATOM 6400 O O . GLY C 3 221 ? 30.893 66.448 72.179 1.00 37.56 ? 227 GLY H O 1 ATOM 6401 O OXT . GLY C 3 221 ? 29.542 65.262 71.007 1.00 37.50 ? 227 GLY H OXT 1 HETATM 6402 C C1 . NAG D 4 . A 44.911 -10.760 130.542 1.00 11.04 ? 469 NAG N C1 1 HETATM 6403 C C2 . NAG D 4 . A 44.147 -11.570 129.548 1.00 12.34 ? 469 NAG N C2 1 HETATM 6404 C C3 . NAG D 4 . A 43.572 -12.867 130.192 1.00 11.64 ? 469 NAG N C3 1 HETATM 6405 C C4 . NAG D 4 . A 44.690 -13.649 130.882 1.00 9.67 ? 469 NAG N C4 1 HETATM 6406 C C5 . NAG D 4 . A 45.347 -12.733 131.908 1.00 7.75 ? 469 NAG N C5 1 HETATM 6407 C C6 . NAG D 4 . A 46.423 -13.366 132.792 1.00 6.63 ? 469 NAG N C6 1 HETATM 6408 C C7 . NAG D 4 . A 42.954 -10.261 127.847 1.00 23.19 ? 469 NAG N C7 1 HETATM 6409 C C8 . NAG D 4 . A 41.719 -9.398 127.575 1.00 24.22 ? 469 NAG N C8 1 HETATM 6410 N N2 . NAG D 4 . A 43.076 -10.695 129.119 1.00 18.17 ? 469 NAG N N2 1 HETATM 6411 O O3 . NAG D 4 . A 42.952 -13.715 129.251 1.00 15.11 ? 469 NAG N O3 1 HETATM 6412 O O4 . NAG D 4 . A 44.156 -14.832 131.506 1.00 11.54 ? 469 NAG N O4 1 HETATM 6413 O O5 . NAG D 4 . A 45.912 -11.602 131.172 1.00 8.21 ? 469 NAG N O5 1 HETATM 6414 O O6 . NAG D 4 . A 47.441 -14.095 132.121 1.00 5.84 ? 469 NAG N O6 1 HETATM 6415 O O7 . NAG D 4 . A 43.808 -10.451 126.956 1.00 23.98 ? 469 NAG N O7 1 HETATM 6416 C C1 . NAG E 4 . B 44.899 -16.058 131.342 1.00 12.18 ? 470 NAG N C1 1 HETATM 6417 C C2 . NAG E 4 . B 44.373 -17.111 132.272 1.00 12.88 ? 470 NAG N C2 1 HETATM 6418 C C3 . NAG E 4 . B 44.991 -18.460 131.985 1.00 14.36 ? 470 NAG N C3 1 HETATM 6419 C C4 . NAG E 4 . B 44.858 -18.783 130.475 1.00 13.81 ? 470 NAG N C4 1 HETATM 6420 C C5 . NAG E 4 . B 45.427 -17.675 129.652 1.00 13.93 ? 470 NAG N C5 1 HETATM 6421 C C6 . NAG E 4 . B 45.263 -17.920 128.165 1.00 15.31 ? 470 NAG N C6 1 HETATM 6422 C C7 . NAG E 4 . B 44.061 -15.957 134.446 1.00 15.16 ? 470 NAG N C7 1 HETATM 6423 C C8 . NAG E 4 . B 44.553 -15.623 135.839 1.00 15.95 ? 470 NAG N C8 1 HETATM 6424 N N2 . NAG E 4 . B 44.753 -16.755 133.633 1.00 13.88 ? 470 NAG N N2 1 HETATM 6425 O O3 . NAG E 4 . B 44.397 -19.455 132.783 1.00 14.93 ? 470 NAG N O3 1 HETATM 6426 O O4 . NAG E 4 . B 45.603 -19.965 130.146 1.00 14.26 ? 470 NAG N O4 1 HETATM 6427 O O5 . NAG E 4 . B 44.756 -16.462 130.000 1.00 12.12 ? 470 NAG N O5 1 HETATM 6428 O O6 . NAG E 4 . B 43.986 -17.406 127.791 1.00 20.77 ? 470 NAG N O6 1 HETATM 6429 O O7 . NAG E 4 . B 42.987 -15.507 134.058 1.00 16.86 ? 470 NAG N O7 1 HETATM 6430 C C1 . BMA F 5 . C 44.895 -21.170 129.848 1.00 11.79 ? 471 BMA N C1 1 HETATM 6431 C C2 . BMA F 5 . C 45.922 -22.020 129.125 1.00 10.71 ? 471 BMA N C2 1 HETATM 6432 C C3 . BMA F 5 . C 45.457 -23.510 129.078 1.00 10.25 ? 471 BMA N C3 1 HETATM 6433 C C4 . BMA F 5 . C 44.810 -23.962 130.380 1.00 12.54 ? 471 BMA N C4 1 HETATM 6434 C C5 . BMA F 5 . C 43.763 -22.986 130.907 1.00 13.27 ? 471 BMA N C5 1 HETATM 6435 C C6 . BMA F 5 . C 43.009 -23.358 132.226 1.00 13.38 ? 471 BMA N C6 1 HETATM 6436 O O2 . BMA F 5 . C 47.180 -21.884 129.766 1.00 8.78 ? 471 BMA N O2 1 HETATM 6437 O O3 . BMA F 5 . C 46.558 -24.442 128.816 1.00 9.28 ? 471 BMA N O3 1 HETATM 6438 O O4 . BMA F 5 . C 44.163 -25.154 130.050 1.00 13.92 ? 471 BMA N O4 1 HETATM 6439 O O5 . BMA F 5 . C 44.466 -21.772 131.062 1.00 12.72 ? 471 BMA N O5 1 HETATM 6440 O O6 . BMA F 5 . C 41.621 -23.003 132.229 1.00 13.97 ? 471 BMA N O6 1 HETATM 6441 C C1 . MAN G 6 . D 46.420 -25.359 127.715 1.00 10.39 ? 472 MAN N C1 1 HETATM 6442 C C2 . MAN G 6 . D 47.569 -26.361 127.540 1.00 11.14 ? 472 MAN N C2 1 HETATM 6443 C C3 . MAN G 6 . D 48.749 -25.671 126.843 1.00 11.34 ? 472 MAN N C3 1 HETATM 6444 C C4 . MAN G 6 . D 48.347 -24.994 125.586 1.00 11.93 ? 472 MAN N C4 1 HETATM 6445 C C5 . MAN G 6 . D 47.331 -23.959 125.941 1.00 12.50 ? 472 MAN N C5 1 HETATM 6446 C C6 . MAN G 6 . D 46.858 -23.137 124.757 1.00 14.32 ? 472 MAN N C6 1 HETATM 6447 O O2 . MAN G 6 . D 46.969 -27.360 126.686 1.00 13.18 ? 472 MAN N O2 1 HETATM 6448 O O3 . MAN G 6 . D 49.764 -26.547 126.480 1.00 11.44 ? 472 MAN N O3 1 HETATM 6449 O O4 . MAN G 6 . D 49.461 -24.442 124.968 1.00 10.15 ? 472 MAN N O4 1 HETATM 6450 O O5 . MAN G 6 . D 46.197 -24.627 126.502 1.00 9.44 ? 472 MAN N O5 1 HETATM 6451 O O6 . MAN G 6 . D 45.609 -22.577 125.141 1.00 19.96 ? 472 MAN N O6 1 HETATM 6452 C C1 . MAN H 6 . E 47.610 -28.593 126.280 1.00 15.47 ? 473 MAN N C1 1 HETATM 6453 C C2 . MAN H 6 . E 46.656 -29.153 125.189 1.00 16.25 ? 473 MAN N C2 1 HETATM 6454 C C3 . MAN H 6 . E 45.363 -29.783 125.856 1.00 18.21 ? 473 MAN N C3 1 HETATM 6455 C C4 . MAN H 6 . E 45.695 -30.624 127.129 1.00 18.43 ? 473 MAN N C4 1 HETATM 6456 C C5 . MAN H 6 . E 46.621 -29.892 128.059 1.00 17.99 ? 473 MAN N C5 1 HETATM 6457 C C6 . MAN H 6 . E 46.960 -30.762 129.263 1.00 18.21 ? 473 MAN N C6 1 HETATM 6458 O O2 . MAN H 6 . E 47.310 -30.152 124.404 1.00 14.34 ? 473 MAN N O2 1 HETATM 6459 O O3 . MAN H 6 . E 44.633 -30.669 124.973 1.00 19.50 ? 473 MAN N O3 1 HETATM 6460 O O4 . MAN H 6 . E 44.488 -30.903 127.843 1.00 19.13 ? 473 MAN N O4 1 HETATM 6461 O O5 . MAN H 6 . E 47.825 -29.550 127.357 1.00 17.75 ? 473 MAN N O5 1 HETATM 6462 O O6 . MAN H 6 . E 47.473 -32.035 128.970 1.00 14.24 ? 473 MAN N O6 1 HETATM 6463 C C1 . MAN I 6 . F 48.106 -29.835 123.281 1.00 13.75 ? 474 MAN N C1 1 HETATM 6464 C C2 . MAN I 6 . F 48.685 -31.167 122.731 1.00 12.61 ? 474 MAN N C2 1 HETATM 6465 C C3 . MAN I 6 . F 49.799 -31.603 123.602 1.00 11.79 ? 474 MAN N C3 1 HETATM 6466 C C4 . MAN I 6 . F 50.905 -30.598 123.589 1.00 13.16 ? 474 MAN N C4 1 HETATM 6467 C C5 . MAN I 6 . F 50.396 -29.297 124.209 1.00 14.80 ? 474 MAN N C5 1 HETATM 6468 C C6 . MAN I 6 . F 51.383 -28.145 123.978 1.00 16.58 ? 474 MAN N C6 1 HETATM 6469 O O2 . MAN I 6 . F 49.170 -31.035 121.433 1.00 12.70 ? 474 MAN N O2 1 HETATM 6470 O O3 . MAN I 6 . F 50.320 -32.803 123.182 1.00 11.28 ? 474 MAN N O3 1 HETATM 6471 O O4 . MAN I 6 . F 51.961 -31.174 124.309 1.00 14.59 ? 474 MAN N O4 1 HETATM 6472 O O5 . MAN I 6 . F 49.128 -28.883 123.606 1.00 15.31 ? 474 MAN N O5 1 HETATM 6473 O O6 . MAN I 6 . F 51.220 -27.585 122.683 1.00 14.54 ? 474 MAN N O6 1 HETATM 6474 C C1 . NAG J 4 . A 59.628 12.664 160.488 1.00 37.50 ? 475 NAG N C1 1 HETATM 6475 C C2 . NAG J 4 . A 60.249 12.519 161.883 1.00 40.50 ? 475 NAG N C2 1 HETATM 6476 C C3 . NAG J 4 . A 59.255 11.676 162.730 1.00 40.98 ? 475 NAG N C3 1 HETATM 6477 C C4 . NAG J 4 . A 57.914 12.448 162.832 1.00 39.95 ? 475 NAG N C4 1 HETATM 6478 C C5 . NAG J 4 . A 57.349 12.555 161.394 1.00 39.17 ? 475 NAG N C5 1 HETATM 6479 C C6 . NAG J 4 . A 56.018 13.303 161.244 1.00 38.67 ? 475 NAG N C6 1 HETATM 6480 C C7 . NAG J 4 . A 62.709 12.676 161.686 1.00 44.14 ? 475 NAG N C7 1 HETATM 6481 C C8 . NAG J 4 . A 64.107 12.077 161.719 1.00 43.62 ? 475 NAG N C8 1 HETATM 6482 N N2 . NAG J 4 . A 61.599 11.931 161.872 1.00 42.86 ? 475 NAG N N2 1 HETATM 6483 O O3 . NAG J 4 . A 59.751 11.401 164.036 1.00 42.26 ? 475 NAG N O3 1 HETATM 6484 O O4 . NAG J 4 . A 57.027 11.782 163.729 1.00 41.47 ? 475 NAG N O4 1 HETATM 6485 O O5 . NAG J 4 . A 58.310 13.236 160.574 1.00 38.51 ? 475 NAG N O5 1 HETATM 6486 O O6 . NAG J 4 . A 55.769 13.494 159.860 1.00 39.20 ? 475 NAG N O6 1 HETATM 6487 O O7 . NAG J 4 . A 62.577 13.884 161.474 1.00 46.52 ? 475 NAG N O7 1 HETATM 6488 C C1 . NAG K 4 . A 63.777 0.406 109.092 1.00 41.83 ? 476 NAG N C1 1 HETATM 6489 C C2 . NAG K 4 . A 62.377 0.939 108.738 1.00 46.08 ? 476 NAG N C2 1 HETATM 6490 C C3 . NAG K 4 . A 62.147 0.538 107.273 1.00 46.92 ? 476 NAG N C3 1 HETATM 6491 C C4 . NAG K 4 . A 63.220 1.333 106.467 1.00 47.82 ? 476 NAG N C4 1 HETATM 6492 C C5 . NAG K 4 . A 64.637 1.005 106.969 1.00 46.27 ? 476 NAG N C5 1 HETATM 6493 C C6 . NAG K 4 . A 65.814 1.745 106.414 1.00 46.64 ? 476 NAG N C6 1 HETATM 6494 C C7 . NAG K 4 . A 61.216 -0.634 110.242 1.00 53.11 ? 476 NAG N C7 1 HETATM 6495 C C8 . NAG K 4 . A 60.113 -0.748 111.297 1.00 52.42 ? 476 NAG N C8 1 HETATM 6496 N N2 . NAG K 4 . A 61.297 0.540 109.632 1.00 50.35 ? 476 NAG N N2 1 HETATM 6497 O O3 . NAG K 4 . A 60.815 0.841 106.927 1.00 48.94 ? 476 NAG N O3 1 HETATM 6498 O O4 . NAG K 4 . A 63.193 1.037 105.061 1.00 50.87 ? 476 NAG N O4 1 HETATM 6499 O O5 . NAG K 4 . A 64.731 1.192 108.376 1.00 43.00 ? 476 NAG N O5 1 HETATM 6500 O O6 . NAG K 4 . A 66.944 1.302 107.138 1.00 46.32 ? 476 NAG N O6 1 HETATM 6501 O O7 . NAG K 4 . A 61.955 -1.577 109.927 1.00 57.42 ? 476 NAG N O7 1 HETATM 6502 C C1 . NAG L 4 . B 62.243 1.697 104.198 1.00 54.19 ? 477 NAG N C1 1 HETATM 6503 C C2 . NAG L 4 . B 62.751 1.534 102.714 1.00 56.39 ? 477 NAG N C2 1 HETATM 6504 C C3 . NAG L 4 . B 61.618 1.580 101.712 1.00 57.37 ? 477 NAG N C3 1 HETATM 6505 C C4 . NAG L 4 . B 60.537 0.599 102.154 1.00 57.52 ? 477 NAG N C4 1 HETATM 6506 C C5 . NAG L 4 . B 59.973 1.143 103.462 1.00 56.81 ? 477 NAG N C5 1 HETATM 6507 C C6 . NAG L 4 . B 58.716 0.473 104.008 1.00 57.12 ? 477 NAG N C6 1 HETATM 6508 C C7 . NAG L 4 . B 64.464 3.424 102.804 1.00 59.06 ? 477 NAG N C7 1 HETATM 6509 C C8 . NAG L 4 . B 65.329 4.357 101.970 1.00 56.55 ? 477 NAG N C8 1 HETATM 6510 N N2 . NAG L 4 . B 63.718 2.505 102.160 1.00 57.93 ? 477 NAG N N2 1 HETATM 6511 O O3 . NAG L 4 . B 62.066 1.272 100.393 1.00 57.66 ? 477 NAG N O3 1 HETATM 6512 O O4 . NAG L 4 . B 59.596 0.538 101.107 1.00 59.68 ? 477 NAG N O4 1 HETATM 6513 O O5 . NAG L 4 . B 60.994 1.023 104.431 1.00 55.08 ? 477 NAG N O5 1 HETATM 6514 O O6 . NAG L 4 . B 58.347 1.133 105.206 1.00 58.05 ? 477 NAG N O6 1 HETATM 6515 O O7 . NAG L 4 . B 64.498 3.517 104.030 1.00 61.84 ? 477 NAG N O7 1 HETATM 6516 CA CA . CA M 7 . ? 46.294 19.879 126.235 1.00 20.50 ? 0 CA N CA 1 HETATM 6517 O O . HOH N 8 . ? 59.124 11.495 119.462 1.00 23.16 ? 478 HOH N O 1 HETATM 6518 O O . HOH N 8 . ? 73.126 22.357 146.997 1.00 17.93 ? 479 HOH N O 1 HETATM 6519 O O . HOH N 8 . ? 64.165 0.362 154.488 1.00 32.49 ? 480 HOH N O 1 HETATM 6520 O O . HOH N 8 . ? 45.383 34.612 122.145 1.00 26.11 ? 481 HOH N O 1 HETATM 6521 O O . HOH N 8 . ? 79.083 35.622 144.654 1.00 40.25 ? 482 HOH N O 1 HETATM 6522 O O . HOH N 8 . ? 72.472 19.708 144.156 1.00 39.75 ? 483 HOH N O 1 HETATM 6523 O O . HOH N 8 . ? 42.542 29.586 143.003 1.00 39.94 ? 484 HOH N O 1 HETATM 6524 O O . HOH N 8 . ? 71.387 3.581 148.045 1.00 37.88 ? 485 HOH N O 1 HETATM 6525 O O . HOH N 8 . ? 52.165 30.004 142.539 1.00 38.14 ? 486 HOH N O 1 HETATM 6526 O O . HOH N 8 . ? 81.795 9.736 130.847 1.00 25.83 ? 487 HOH N O 1 HETATM 6527 O O . HOH N 8 . ? 80.652 11.766 128.512 1.00 17.95 ? 488 HOH N O 1 HETATM 6528 O O . HOH N 8 . ? 75.598 4.511 118.634 1.00 4.14 ? 489 HOH N O 1 HETATM 6529 O O . HOH N 8 . ? 48.046 20.532 130.655 1.00 20.70 ? 490 HOH N O 1 HETATM 6530 O O . HOH N 8 . ? 54.535 7.378 126.399 1.00 42.08 ? 491 HOH N O 1 HETATM 6531 O O . HOH N 8 . ? 62.195 -0.517 121.409 1.00 45.06 ? 492 HOH N O 1 HETATM 6532 O O . HOH N 8 . ? 74.985 16.775 143.022 1.00 38.73 ? 493 HOH N O 1 HETATM 6533 O O . HOH N 8 . ? 46.155 -1.371 130.546 1.00 23.71 ? 494 HOH N O 1 HETATM 6534 O O . HOH N 8 . ? 69.138 21.549 148.005 1.00 37.12 ? 495 HOH N O 1 HETATM 6535 O O . HOH N 8 . ? 70.684 8.817 122.839 1.00 15.60 ? 496 HOH N O 1 HETATM 6536 O O . HOH N 8 . ? 71.223 29.189 145.294 1.00 22.03 ? 497 HOH N O 1 HETATM 6537 O O . HOH N 8 . ? 60.008 12.699 131.212 1.00 24.82 ? 498 HOH N O 1 HETATM 6538 O O . HOH N 8 . ? 62.169 13.929 138.292 1.00 37.24 ? 499 HOH N O 1 HETATM 6539 O O . HOH N 8 . ? 51.801 28.791 145.048 1.00 45.87 ? 500 HOH N O 1 HETATM 6540 O O . HOH N 8 . ? 64.810 10.469 145.491 1.00 35.04 ? 501 HOH N O 1 HETATM 6541 O O . HOH N 8 . ? 67.050 36.256 134.101 1.00 13.75 ? 502 HOH N O 1 HETATM 6542 O O . HOH N 8 . ? 60.277 6.888 133.169 1.00 11.17 ? 503 HOH N O 1 HETATM 6543 O O . HOH N 8 . ? 50.374 9.474 133.260 1.00 30.23 ? 504 HOH N O 1 HETATM 6544 O O . HOH N 8 . ? 54.325 11.936 123.840 1.00 40.75 ? 505 HOH N O 1 HETATM 6545 O O . HOH N 8 . ? 76.262 10.394 139.906 1.00 25.04 ? 506 HOH N O 1 HETATM 6546 O O . HOH N 8 . ? 77.728 3.537 135.959 1.00 32.42 ? 507 HOH N O 1 HETATM 6547 O O . HOH N 8 . ? 77.193 17.896 135.506 1.00 51.62 ? 508 HOH N O 1 HETATM 6548 O O . HOH N 8 . ? 71.299 -2.950 116.310 1.00 24.20 ? 509 HOH N O 1 HETATM 6549 O O . HOH N 8 . ? 71.763 -1.948 118.761 1.00 14.57 ? 510 HOH N O 1 HETATM 6550 O O . HOH N 8 . ? 58.477 8.889 120.564 1.00 29.06 ? 511 HOH N O 1 HETATM 6551 O O . HOH N 8 . ? 58.443 -3.252 128.468 1.00 36.45 ? 512 HOH N O 1 HETATM 6552 O O . HOH N 8 . ? 57.564 -4.403 135.270 1.00 31.68 ? 513 HOH N O 1 HETATM 6553 O O . HOH N 8 . ? 60.168 -5.234 136.245 1.00 31.75 ? 514 HOH N O 1 HETATM 6554 O O . HOH N 8 . ? 53.274 -7.176 130.903 1.00 40.45 ? 515 HOH N O 1 HETATM 6555 O O . HOH N 8 . ? 50.682 -7.502 132.523 1.00 15.08 ? 516 HOH N O 1 HETATM 6556 O O . HOH N 8 . ? 40.086 11.959 133.800 1.00 67.78 ? 517 HOH N O 1 HETATM 6557 O O . HOH N 8 . ? 42.737 11.650 134.171 1.00 33.45 ? 518 HOH N O 1 HETATM 6558 O O . HOH N 8 . ? 69.147 10.362 127.617 1.00 36.80 ? 519 HOH N O 1 HETATM 6559 O O . HOH N 8 . ? 82.505 2.467 118.973 1.00 38.70 ? 520 HOH N O 1 HETATM 6560 O O . HOH N 8 . ? 68.200 5.031 111.533 1.00 27.27 ? 521 HOH N O 1 HETATM 6561 O O . HOH N 8 . ? 62.165 11.392 148.666 1.00 6.55 ? 522 HOH N O 1 HETATM 6562 O O . HOH N 8 . ? 62.564 12.013 145.965 1.00 23.45 ? 523 HOH N O 1 HETATM 6563 O O . HOH N 8 . ? 62.394 12.816 150.947 1.00 36.73 ? 524 HOH N O 1 HETATM 6564 O O . HOH N 8 . ? 55.282 11.545 143.472 1.00 36.92 ? 525 HOH N O 1 HETATM 6565 O O . HOH N 8 . ? 61.746 16.934 143.374 1.00 27.15 ? 526 HOH N O 1 HETATM 6566 O O . HOH N 8 . ? 54.408 10.590 156.624 1.00 23.69 ? 527 HOH N O 1 HETATM 6567 O O . HOH N 8 . ? 50.974 10.639 136.157 1.00 30.72 ? 528 HOH N O 1 HETATM 6568 O O . HOH N 8 . ? 58.437 20.534 128.474 1.00 23.63 ? 529 HOH N O 1 HETATM 6569 O O . HOH N 8 . ? 56.413 20.797 139.386 1.00 44.43 ? 530 HOH N O 1 HETATM 6570 O O . HOH N 8 . ? 49.447 27.512 133.077 1.00 26.53 ? 531 HOH N O 1 HETATM 6571 O O . HOH N 8 . ? 46.978 28.550 133.305 1.00 49.54 ? 532 HOH N O 1 HETATM 6572 O O . HOH N 8 . ? 56.026 21.506 129.239 1.00 11.44 ? 533 HOH N O 1 HETATM 6573 O O . HOH N 8 . ? 55.924 23.674 127.609 1.00 32.86 ? 534 HOH N O 1 HETATM 6574 O O . HOH N 8 . ? 58.438 14.880 119.259 1.00 43.73 ? 535 HOH N O 1 HETATM 6575 O O . HOH N 8 . ? 63.028 34.299 128.249 1.00 30.40 ? 536 HOH N O 1 HETATM 6576 O O . HOH N 8 . ? 71.642 29.006 130.329 1.00 37.25 ? 537 HOH N O 1 HETATM 6577 O O . HOH N 8 . ? 60.574 15.199 117.041 1.00 43.15 ? 538 HOH N O 1 HETATM 6578 O O . HOH N 8 . ? 69.244 35.026 134.636 1.00 22.10 ? 539 HOH N O 1 HETATM 6579 O O . HOH N 8 . ? 60.751 6.786 121.924 1.00 45.82 ? 540 HOH N O 1 HETATM 6580 O O . HOH O 8 . ? 41.641 20.983 110.276 1.00 20.92 ? 215 HOH L O 1 HETATM 6581 O O . HOH O 8 . ? 29.374 50.360 82.521 1.00 14.85 ? 216 HOH L O 1 HETATM 6582 O O . HOH P 8 . ? 67.082 33.842 103.806 1.00 43.46 ? 228 HOH H O 1 HETATM 6583 O O . HOH P 8 . ? 49.800 34.888 109.273 1.00 35.77 ? 229 HOH H O 1 HETATM 6584 O O . HOH P 8 . ? 56.719 38.824 76.372 1.00 48.76 ? 230 HOH H O 1 HETATM 6585 O O . HOH P 8 . ? 50.449 37.209 119.464 1.00 38.27 ? 231 HOH H O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ILE 1 81 81 ILE ILE N . n A 1 2 ARG 2 82 82 ARG ARG N . n A 1 3 GLU 3 83 83 GLU GLU N . n A 1 4 PHE 4 84 84 PHE PHE N . n A 1 5 ASN 5 85 85 ASN ASN N . n A 1 6 ASN 6 86 86 ASN ASN N . n A 1 7 LEU 7 87 87 LEU LEU N . n A 1 8 THR 8 88 88 THR THR N . n A 1 9 LYS 9 89 89 LYS LYS N . n A 1 10 GLY 10 90 90 GLY GLY N . n A 1 11 LEU 11 91 91 LEU LEU N . n A 1 12 CYS 12 92 92 CYS CYS N . n A 1 13 THR 13 93 93 THR THR N . n A 1 14 ILE 14 94 94 ILE ILE N . n A 1 15 ASN 15 95 95 ASN ASN N . n A 1 16 SER 16 96 96 SER SER N . n A 1 17 TRP 17 97 97 TRP TRP N . n A 1 18 HIS 18 98 98 HIS HIS N . n A 1 19 ILE 19 99 99 ILE ILE N . n A 1 20 TYR 20 100 100 TYR TYR N . n A 1 21 GLY 21 101 101 GLY GLY N . n A 1 22 LYS 22 102 102 LYS LYS N . n A 1 23 ASP 23 103 103 ASP ASP N . n A 1 24 ASN 24 104 104 ASN ASN N . n A 1 25 ALA 25 105 105 ALA ALA N . n A 1 26 VAL 26 106 106 VAL VAL N . n A 1 27 ARG 27 107 107 ARG ARG N . n A 1 28 ILE 28 108 108 ILE ILE N . n A 1 29 GLY 29 109 109 GLY GLY N . n A 1 30 GLU 30 110 110 GLU GLU N . n A 1 31 ASP 31 111 111 ASP ASP N . n A 1 32 SER 32 112 112 SER SER N . n A 1 33 ASP 33 113 113 ASP ASP N . n A 1 34 VAL 34 114 114 VAL VAL N . n A 1 35 LEU 35 115 115 LEU LEU N . n A 1 36 VAL 36 116 116 VAL VAL N . n A 1 37 THR 37 117 117 THR THR N . n A 1 38 ARG 38 118 118 ARG ARG N . n A 1 39 GLU 39 119 119 GLU GLU N . n A 1 40 PRO 40 120 120 PRO PRO N . n A 1 41 TYR 41 121 121 TYR TYR N . n A 1 42 VAL 42 122 122 VAL VAL N . n A 1 43 SER 43 123 123 SER SER N . n A 1 44 CYS 44 124 124 CYS CYS N . n A 1 45 ASP 45 125 125 ASP ASP N . n A 1 46 PRO 46 126 126 PRO PRO N . n A 1 47 ASP 47 127 127 ASP ASP N . n A 1 48 GLU 48 128 128 GLU GLU N . n A 1 49 CYS 49 129 129 CYS CYS N . n A 1 50 ARG 50 130 130 ARG ARG N . n A 1 51 PHE 51 131 131 PHE PHE N . n A 1 52 TYR 52 132 132 TYR TYR N . n A 1 53 ALA 53 133 133 ALA ALA N . n A 1 54 LEU 54 134 134 LEU LEU N . n A 1 55 SER 55 135 135 SER SER N . n A 1 56 GLN 56 136 136 GLN GLN N . n A 1 57 GLY 57 137 137 GLY GLY N . n A 1 58 THR 58 138 138 THR THR N . n A 1 59 THR 59 139 139 THR THR N . n A 1 60 ILE 60 140 140 ILE ILE N . n A 1 61 ARG 61 141 141 ARG ARG N . n A 1 62 GLY 62 142 142 GLY GLY N . n A 1 63 LYS 63 143 143 LYS LYS N . n A 1 64 HIS 64 144 144 HIS HIS N . n A 1 65 SER 65 145 145 SER SER N . n A 1 66 ASN 66 146 146 ASN ASN N . n A 1 67 GLY 67 147 147 GLY GLY N . n A 1 68 THR 68 148 148 THR THR N . n A 1 69 ILE 69 149 149 ILE ILE N . n A 1 70 HIS 70 150 150 HIS HIS N . n A 1 71 ASP 71 151 151 ASP ASP N . n A 1 72 ARG 72 152 152 ARG ARG N . n A 1 73 SER 73 153 153 SER SER N . n A 1 74 GLN 74 154 154 GLN GLN N . n A 1 75 TYR 75 155 155 TYR TYR N . n A 1 76 ARG 76 156 156 ARG ARG N . n A 1 77 ASP 77 157 157 ASP ASP N . n A 1 78 LEU 78 158 158 LEU LEU N . n A 1 79 ILE 79 159 159 ILE ILE N . n A 1 80 SER 80 160 160 SER SER N . n A 1 81 TRP 81 161 161 TRP TRP N . n A 1 82 PRO 82 162 162 PRO PRO N . n A 1 83 LEU 83 163 163 LEU LEU N . n A 1 84 SER 84 164 164 SER SER N . n A 1 85 SER 85 165 165 SER SER N . n A 1 86 PRO 86 166 166 PRO PRO N . n A 1 87 PRO 87 167 167 PRO PRO N . n A 1 88 THR 88 168 168 THR THR N . n A 1 89 VAL 89 169 169 VAL VAL N . n A 1 90 TYR 90 169 169 TYR TYR N A n A 1 91 ASN 91 170 170 ASN ASN N . n A 1 92 SER 92 171 171 SER SER N . n A 1 93 ARG 93 172 172 ARG ARG N . n A 1 94 VAL 94 173 173 VAL VAL N . n A 1 95 GLU 95 174 174 GLU GLU N . n A 1 96 CYS 96 175 175 CYS CYS N . n A 1 97 ILE 97 176 176 ILE ILE N . n A 1 98 GLY 98 177 177 GLY GLY N . n A 1 99 TRP 99 178 178 TRP TRP N . n A 1 100 SER 100 179 179 SER SER N . n A 1 101 SER 101 180 180 SER SER N . n A 1 102 THR 102 181 181 THR THR N . n A 1 103 SER 103 182 182 SER SER N . n A 1 104 CYS 104 183 183 CYS CYS N . n A 1 105 HIS 105 184 184 HIS HIS N . n A 1 106 ASP 106 185 185 ASP ASP N . n A 1 107 GLY 107 186 186 GLY GLY N . n A 1 108 ARG 108 187 187 ARG ARG N . n A 1 109 ALA 109 188 188 ALA ALA N . n A 1 110 ARG 110 189 189 ARG ARG N . n A 1 111 MET 111 190 190 MET MET N . n A 1 112 SER 112 191 191 SER SER N . n A 1 113 ILE 113 192 192 ILE ILE N . n A 1 114 CYS 114 193 193 CYS CYS N . n A 1 115 ILE 115 194 194 ILE ILE N . n A 1 116 SER 116 195 195 SER SER N . n A 1 117 GLY 117 196 196 GLY GLY N . n A 1 118 PRO 118 197 197 PRO PRO N . n A 1 119 ASN 119 198 198 ASN ASN N . n A 1 120 ASN 120 199 199 ASN ASN N . n A 1 121 ASN 121 200 200 ASN ASN N . n A 1 122 ALA 122 201 201 ALA ALA N . n A 1 123 SER 123 202 202 SER SER N . n A 1 124 ALA 124 203 203 ALA ALA N . n A 1 125 VAL 125 204 204 VAL VAL N . n A 1 126 ILE 126 205 205 ILE ILE N . n A 1 127 TRP 127 206 206 TRP TRP N . n A 1 128 TYR 128 207 207 TYR TYR N . n A 1 129 ASN 129 208 208 ASN ASN N . n A 1 130 ARG 130 209 209 ARG ARG N . n A 1 131 ARG 131 210 210 ARG ARG N . n A 1 132 PRO 132 211 211 PRO PRO N . n A 1 133 VAL 133 212 212 VAL VAL N . n A 1 134 THR 134 213 213 THR THR N . n A 1 135 GLU 135 214 214 GLU GLU N . n A 1 136 ILE 136 215 215 ILE ILE N . n A 1 137 ASN 137 216 216 ASN ASN N . n A 1 138 THR 138 217 217 THR THR N . n A 1 139 TRP 139 218 218 TRP TRP N . n A 1 140 ALA 140 219 219 ALA ALA N . n A 1 141 ARG 141 220 220 ARG ARG N . n A 1 142 ASN 142 221 221 ASN ASN N . n A 1 143 ILE 143 222 222 ILE ILE N . n A 1 144 LEU 144 223 223 LEU LEU N . n A 1 145 ARG 145 224 224 ARG ARG N . n A 1 146 THR 146 225 225 THR THR N . n A 1 147 GLN 147 226 226 GLN GLN N . n A 1 148 GLU 148 227 227 GLU GLU N . n A 1 149 SER 149 228 228 SER SER N . n A 1 150 GLU 150 229 229 GLU GLU N . n A 1 151 CYS 151 230 230 CYS CYS N . n A 1 152 VAL 152 231 231 VAL VAL N . n A 1 153 CYS 153 232 232 CYS CYS N . n A 1 154 GLN 154 233 233 GLN GLN N . n A 1 155 ASN 155 234 234 ASN ASN N . n A 1 156 GLY 156 235 235 GLY GLY N . n A 1 157 VAL 157 236 236 VAL VAL N . n A 1 158 CYS 158 237 237 CYS CYS N . n A 1 159 PRO 159 238 238 PRO PRO N . n A 1 160 VAL 160 239 239 VAL VAL N . n A 1 161 VAL 161 240 240 VAL VAL N . n A 1 162 PHE 162 241 241 PHE PHE N . n A 1 163 THR 163 242 242 THR THR N . n A 1 164 ASP 164 243 243 ASP ASP N . n A 1 165 GLY 165 244 244 GLY GLY N . n A 1 166 SER 166 245 245 SER SER N . n A 1 167 ALA 167 246 246 ALA ALA N . n A 1 168 THR 168 247 247 THR THR N . n A 1 169 GLY 169 248 248 GLY GLY N . n A 1 170 PRO 170 249 249 PRO PRO N . n A 1 171 ALA 171 250 250 ALA ALA N . n A 1 172 GLU 172 251 251 GLU GLU N . n A 1 173 THR 173 252 252 THR THR N . n A 1 174 ARG 174 253 253 ARG ARG N . n A 1 175 ILE 175 254 254 ILE ILE N . n A 1 176 TYR 176 255 255 TYR TYR N . n A 1 177 TYR 177 256 256 TYR TYR N . n A 1 178 PHE 178 257 257 PHE PHE N . n A 1 179 LYS 179 258 258 LYS LYS N . n A 1 180 GLU 180 259 259 GLU GLU N . n A 1 181 GLY 181 260 260 GLY GLY N . n A 1 182 LYS 182 261 261 LYS LYS N . n A 1 183 ILE 183 262 262 ILE ILE N . n A 1 184 LEU 184 263 263 LEU LEU N . n A 1 185 LYS 185 264 264 LYS LYS N . n A 1 186 TRP 186 265 265 TRP TRP N . n A 1 187 GLU 187 266 266 GLU GLU N . n A 1 188 PRO 188 267 267 PRO PRO N . n A 1 189 LEU 189 268 268 LEU LEU N . n A 1 190 THR 190 269 269 THR THR N . n A 1 191 GLY 191 270 270 GLY GLY N . n A 1 192 THR 192 271 271 THR THR N . n A 1 193 ALA 193 272 272 ALA ALA N . n A 1 194 LYS 194 273 273 LYS LYS N . n A 1 195 HIS 195 274 274 HIS HIS N . n A 1 196 ILE 196 275 275 ILE ILE N . n A 1 197 GLU 197 276 276 GLU GLU N . n A 1 198 GLU 198 277 277 GLU GLU N . n A 1 199 CYS 199 278 278 CYS CYS N . n A 1 200 SER 200 279 279 SER SER N . n A 1 201 CYS 201 280 280 CYS CYS N . n A 1 202 TYR 202 281 281 TYR TYR N . n A 1 203 GLY 203 282 282 GLY GLY N . n A 1 204 GLU 204 283 283 GLU GLU N . n A 1 205 GLN 205 284 284 GLN GLN N . n A 1 206 ALA 206 285 285 ALA ALA N . n A 1 207 GLY 207 286 286 GLY GLY N . n A 1 208 VAL 208 287 287 VAL VAL N . n A 1 209 THR 209 288 288 THR THR N . n A 1 210 CYS 210 289 289 CYS CYS N . n A 1 211 THR 211 290 290 THR THR N . n A 1 212 CYS 212 291 291 CYS CYS N . n A 1 213 ARG 213 292 292 ARG ARG N . n A 1 214 ASP 214 293 293 ASP ASP N . n A 1 215 ASN 215 294 294 ASN ASN N . n A 1 216 TRP 216 295 295 TRP TRP N . n A 1 217 GLN 217 296 296 GLN GLN N . n A 1 218 GLY 218 297 297 GLY GLY N . n A 1 219 SER 219 298 298 SER SER N . n A 1 220 ASN 220 299 299 ASN ASN N . n A 1 221 ARG 221 300 300 ARG ARG N . n A 1 222 PRO 222 301 301 PRO PRO N . n A 1 223 VAL 223 302 302 VAL VAL N . n A 1 224 ILE 224 303 303 ILE ILE N . n A 1 225 GLN 225 304 304 GLN GLN N . n A 1 226 ILE 226 305 305 ILE ILE N . n A 1 227 ASP 227 306 306 ASP ASP N . n A 1 228 PRO 228 307 307 PRO PRO N . n A 1 229 VAL 229 308 308 VAL VAL N . n A 1 230 ALA 230 309 309 ALA ALA N . n A 1 231 MET 231 310 310 MET MET N . n A 1 232 THR 232 311 311 THR THR N . n A 1 233 HIS 233 312 312 HIS HIS N . n A 1 234 THR 234 313 313 THR THR N . n A 1 235 SER 235 314 314 SER SER N . n A 1 236 GLN 236 315 315 GLN GLN N . n A 1 237 TYR 237 316 316 TYR TYR N . n A 1 238 ILE 238 317 317 ILE ILE N . n A 1 239 CYS 239 318 318 CYS CYS N . n A 1 240 SER 240 319 319 SER SER N . n A 1 241 PRO 241 320 320 PRO PRO N . n A 1 242 VAL 242 321 321 VAL VAL N . n A 1 243 LEU 243 322 322 LEU LEU N . n A 1 244 THR 244 323 323 THR THR N . n A 1 245 ASP 245 324 324 ASP ASP N . n A 1 246 ASN 246 325 325 ASN ASN N . n A 1 247 PRO 247 326 326 PRO PRO N . n A 1 248 ARG 248 327 327 ARG ARG N . n A 1 249 PRO 249 328 328 PRO PRO N . n A 1 250 ASN 250 329 329 ASN ASN N . n A 1 251 ASP 251 330 330 ASP ASP N . n A 1 252 PRO 252 331 331 PRO PRO N . n A 1 253 THR 253 332 332 THR THR N . n A 1 254 VAL 254 333 333 VAL VAL N . n A 1 255 GLY 255 335 335 GLY GLY N . n A 1 256 LYS 256 336 336 LYS LYS N . n A 1 257 CYS 257 337 337 CYS CYS N . n A 1 258 ASN 258 338 338 ASN ASN N . n A 1 259 ASP 259 339 339 ASP ASP N . n A 1 260 PRO 260 340 340 PRO PRO N . n A 1 261 TYR 261 341 341 TYR TYR N . n A 1 262 PRO 262 342 342 PRO PRO N . n A 1 263 GLY 263 343 343 GLY GLY N . n A 1 264 ASN 264 344 344 ASN ASN N . n A 1 265 ASN 265 345 345 ASN ASN N . n A 1 266 ASN 266 346 346 ASN ASN N . n A 1 267 ASN 267 347 347 ASN ASN N . n A 1 268 GLY 268 348 348 GLY GLY N . n A 1 269 VAL 269 349 349 VAL VAL N . n A 1 270 LYS 270 350 350 LYS LYS N . n A 1 271 GLY 271 351 351 GLY GLY N . n A 1 272 PHE 272 352 352 PHE PHE N . n A 1 273 SER 273 353 353 SER SER N . n A 1 274 TYR 274 354 354 TYR TYR N . n A 1 275 LEU 275 355 355 LEU LEU N . n A 1 276 ASP 276 356 356 ASP ASP N . n A 1 277 GLY 277 357 357 GLY GLY N . n A 1 278 GLY 278 358 358 GLY GLY N . n A 1 279 ASN 279 359 359 ASN ASN N . n A 1 280 THR 280 360 360 THR THR N . n A 1 281 TRP 281 361 361 TRP TRP N . n A 1 282 LEU 282 362 362 LEU LEU N . n A 1 283 GLY 283 363 363 GLY GLY N . n A 1 284 ARG 284 364 364 ARG ARG N . n A 1 285 THR 285 365 365 THR THR N . n A 1 286 ILE 286 366 366 ILE ILE N . n A 1 287 SER 287 367 367 SER SER N . n A 1 288 ILE 288 368 368 ILE ILE N . n A 1 289 ALA 289 369 369 ALA ALA N . n A 1 290 SER 290 370 370 SER SER N . n A 1 291 ARG 291 371 371 ARG ARG N . n A 1 292 SER 292 372 372 SER SER N . n A 1 293 GLY 293 373 373 GLY GLY N . n A 1 294 TYR 294 374 374 TYR TYR N . n A 1 295 GLU 295 375 375 GLU GLU N . n A 1 296 MET 296 376 376 MET MET N . n A 1 297 LEU 297 377 377 LEU LEU N . n A 1 298 LYS 298 378 378 LYS LYS N . n A 1 299 VAL 299 379 379 VAL VAL N . n A 1 300 PRO 300 380 380 PRO PRO N . n A 1 301 ASN 301 381 381 ASN ASN N . n A 1 302 ALA 302 382 382 ALA ALA N . n A 1 303 LEU 303 383 383 LEU LEU N . n A 1 304 THR 304 384 384 THR THR N . n A 1 305 ASP 305 385 385 ASP ASP N . n A 1 306 ASP 306 386 386 ASP ASP N . n A 1 307 ARG 307 387 387 ARG ARG N . n A 1 308 SER 308 388 388 SER SER N . n A 1 309 LYS 309 389 389 LYS LYS N . n A 1 310 PRO 310 390 390 PRO PRO N . n A 1 311 THR 311 391 391 THR THR N . n A 1 312 GLN 312 392 392 GLN GLN N . n A 1 313 GLY 313 394 394 GLY GLY N . n A 1 314 GLN 314 395 395 GLN GLN N . n A 1 315 THR 315 396 396 THR THR N . n A 1 316 ILE 316 397 397 ILE ILE N . n A 1 317 VAL 317 398 398 VAL VAL N . n A 1 318 LEU 318 399 399 LEU LEU N . n A 1 319 ASN 319 400 400 ASN ASN N . n A 1 320 THR 320 401 401 THR THR N . n A 1 321 ASP 321 402 402 ASP ASP N . n A 1 322 TRP 322 403 403 TRP TRP N . n A 1 323 SER 323 404 404 SER SER N . n A 1 324 GLY 324 405 405 GLY GLY N . n A 1 325 TYR 325 406 406 TYR TYR N . n A 1 326 SER 326 407 407 SER SER N . n A 1 327 GLY 327 408 408 GLY GLY N . n A 1 328 SER 328 409 409 SER SER N . n A 1 329 PHE 329 410 410 PHE PHE N . n A 1 330 MET 330 411 411 MET MET N . n A 1 331 ASP 331 412 412 ASP ASP N . n A 1 332 TYR 332 412 412 TYR TYR N A n A 1 333 TRP 333 412 412 TRP TRP N B n A 1 334 ALA 334 413 413 ALA ALA N . n A 1 335 GLU 335 414 414 GLU GLU N . n A 1 336 GLY 336 415 415 GLY GLY N . n A 1 337 GLU 337 416 416 GLU GLU N . n A 1 338 CYS 338 417 417 CYS CYS N . n A 1 339 TYR 339 418 418 TYR TYR N . n A 1 340 ARG 340 419 419 ARG ARG N . n A 1 341 ALA 341 420 420 ALA ALA N . n A 1 342 CYS 342 421 421 CYS CYS N . n A 1 343 PHE 343 422 422 PHE PHE N . n A 1 344 TYR 344 423 423 TYR TYR N . n A 1 345 VAL 345 424 424 VAL VAL N . n A 1 346 GLU 346 425 425 GLU GLU N . n A 1 347 LEU 347 426 426 LEU LEU N . n A 1 348 ILE 348 427 427 ILE ILE N . n A 1 349 ARG 349 428 428 ARG ARG N . n A 1 350 GLY 350 429 429 GLY GLY N . n A 1 351 ARG 351 430 430 ARG ARG N . n A 1 352 PRO 352 431 431 PRO PRO N . n A 1 353 LYS 353 432 432 LYS LYS N . n A 1 354 GLU 354 433 433 GLU GLU N . n A 1 355 ASP 355 434 434 ASP ASP N . n A 1 356 LYS 356 435 435 LYS LYS N . n A 1 357 VAL 357 436 436 VAL VAL N . n A 1 358 TRP 358 437 437 TRP TRP N . n A 1 359 TRP 359 438 438 TRP TRP N . n A 1 360 THR 360 439 439 THR THR N . n A 1 361 SER 361 440 440 SER SER N . n A 1 362 ASN 362 441 441 ASN ASN N . n A 1 363 SER 363 442 442 SER SER N . n A 1 364 ILE 364 443 443 ILE ILE N . n A 1 365 VAL 365 444 444 VAL VAL N . n A 1 366 SER 366 445 445 SER SER N . n A 1 367 MET 367 446 446 MET MET N . n A 1 368 CYS 368 447 447 CYS CYS N . n A 1 369 SER 369 448 448 SER SER N . n A 1 370 SER 370 449 449 SER SER N . n A 1 371 THR 371 450 450 THR THR N . n A 1 372 GLU 372 451 451 GLU GLU N . n A 1 373 PHE 373 452 452 PHE PHE N . n A 1 374 LEU 374 453 453 LEU LEU N . n A 1 375 GLY 375 454 454 GLY GLY N . n A 1 376 GLN 376 455 455 GLN GLN N . n A 1 377 TRP 377 456 456 TRP TRP N . n A 1 378 ASN 378 457 457 ASN ASN N . n A 1 379 TRP 379 458 458 TRP TRP N . n A 1 380 PRO 380 459 459 PRO PRO N . n A 1 381 ASP 381 460 460 ASP ASP N . n A 1 382 GLY 382 461 461 GLY GLY N . n A 1 383 ALA 383 462 462 ALA ALA N . n A 1 384 LYS 384 463 463 LYS LYS N . n A 1 385 ILE 385 464 464 ILE ILE N . n A 1 386 GLU 386 465 465 GLU GLU N . n A 1 387 TYR 387 466 466 TYR TYR N . n A 1 388 PHE 388 467 467 PHE PHE N . n A 1 389 LEU 389 468 468 LEU LEU N . n B 2 1 ASP 1 1 1 ASP ASP L . n B 2 2 ILE 2 2 2 ILE ILE L . n B 2 3 VAL 3 3 3 VAL VAL L . n B 2 4 MET 4 4 4 MET MET L . n B 2 5 THR 5 5 5 THR THR L . n B 2 6 GLN 6 6 6 GLN GLN L . n B 2 7 SER 7 7 7 SER SER L . n B 2 8 PRO 8 8 8 PRO PRO L . n B 2 9 LYS 9 9 9 LYS LYS L . n B 2 10 PHE 10 10 10 PHE PHE L . n B 2 11 MET 11 11 11 MET MET L . n B 2 12 SER 12 12 12 SER SER L . n B 2 13 THR 13 13 13 THR THR L . n B 2 14 SER 14 14 14 SER SER L . n B 2 15 VAL 15 15 15 VAL VAL L . n B 2 16 GLY 16 16 16 GLY GLY L . n B 2 17 ASP 17 17 17 ASP ASP L . n B 2 18 ARG 18 18 18 ARG ARG L . n B 2 19 VAL 19 19 19 VAL VAL L . n B 2 20 THR 20 20 20 THR THR L . n B 2 21 ILE 21 21 21 ILE ILE L . n B 2 22 THR 22 22 22 THR THR L . n B 2 23 CYS 23 23 23 CYS CYS L . n B 2 24 LYS 24 24 24 LYS LYS L . n B 2 25 ALA 25 25 25 ALA ALA L . n B 2 26 SER 26 26 26 SER SER L . n B 2 27 GLN 27 27 27 GLN GLN L . n B 2 28 ASP 28 28 28 ASP ASP L . n B 2 29 VAL 29 29 29 VAL VAL L . n B 2 30 SER 30 30 30 SER SER L . n B 2 31 THR 31 31 31 THR THR L . n B 2 32 ALA 32 32 32 ALA ALA L . n B 2 33 VAL 33 33 33 VAL VAL L . n B 2 34 VAL 34 34 34 VAL VAL L . n B 2 35 TRP 35 35 35 TRP TRP L . n B 2 36 TYR 36 36 36 TYR TYR L . n B 2 37 GLN 37 37 37 GLN GLN L . n B 2 38 GLN 38 38 38 GLN GLN L . n B 2 39 LYS 39 39 39 LYS LYS L . n B 2 40 PRO 40 40 40 PRO PRO L . n B 2 41 GLY 41 41 41 GLY GLY L . n B 2 42 GLN 42 42 42 GLN GLN L . n B 2 43 SER 43 43 43 SER SER L . n B 2 44 PRO 44 44 44 PRO PRO L . n B 2 45 LYS 45 45 45 LYS LYS L . n B 2 46 LEU 46 46 46 LEU LEU L . n B 2 47 LEU 47 47 47 LEU LEU L . n B 2 48 ILE 48 48 48 ILE ILE L . n B 2 49 TYR 49 49 49 TYR TYR L . n B 2 50 TRP 50 50 50 TRP TRP L . n B 2 51 ALA 51 51 51 ALA ALA L . n B 2 52 SER 52 52 52 SER SER L . n B 2 53 THR 53 53 53 THR THR L . n B 2 54 ARG 54 54 54 ARG ARG L . n B 2 55 HIS 55 55 55 HIS HIS L . n B 2 56 ILE 56 56 56 ILE ILE L . n B 2 57 GLY 57 57 57 GLY GLY L . n B 2 58 VAL 58 58 58 VAL VAL L . n B 2 59 PRO 59 59 59 PRO PRO L . n B 2 60 ASP 60 60 60 ASP ASP L . n B 2 61 ARG 61 61 61 ARG ARG L . n B 2 62 PHE 62 62 62 PHE PHE L . n B 2 63 ALA 63 63 63 ALA ALA L . n B 2 64 GLY 64 64 64 GLY GLY L . n B 2 65 SER 65 65 65 SER SER L . n B 2 66 GLY 66 66 66 GLY GLY L . n B 2 67 SER 67 67 67 SER SER L . n B 2 68 GLY 68 68 68 GLY GLY L . n B 2 69 THR 69 69 69 THR THR L . n B 2 70 ASP 70 70 70 ASP ASP L . n B 2 71 TYR 71 71 71 TYR TYR L . n B 2 72 THR 72 72 72 THR THR L . n B 2 73 LEU 73 73 73 LEU LEU L . n B 2 74 THR 74 74 74 THR THR L . n B 2 75 ILE 75 75 75 ILE ILE L . n B 2 76 SER 76 76 76 SER SER L . n B 2 77 SER 77 77 77 SER SER L . n B 2 78 VAL 78 78 78 VAL VAL L . n B 2 79 GLN 79 79 79 GLN GLN L . n B 2 80 ALA 80 80 80 ALA ALA L . n B 2 81 GLU 81 81 81 GLU GLU L . n B 2 82 ASP 82 82 82 ASP ASP L . n B 2 83 LEU 83 83 83 LEU LEU L . n B 2 84 ALA 84 84 84 ALA ALA L . n B 2 85 LEU 85 85 85 LEU LEU L . n B 2 86 TYR 86 86 86 TYR TYR L . n B 2 87 TYR 87 87 87 TYR TYR L . n B 2 88 CYS 88 88 88 CYS CYS L . n B 2 89 GLN 89 89 89 GLN GLN L . n B 2 90 GLN 90 90 90 GLN GLN L . n B 2 91 HIS 91 91 91 HIS HIS L . n B 2 92 TYR 92 92 92 TYR TYR L . n B 2 93 SER 93 93 93 SER SER L . n B 2 94 PRO 94 94 94 PRO PRO L . n B 2 95 PRO 95 95 95 PRO PRO L . n B 2 96 TRP 96 96 96 TRP TRP L . n B 2 97 THR 97 97 97 THR THR L . n B 2 98 PHE 98 98 98 PHE PHE L . n B 2 99 GLY 99 99 99 GLY GLY L . n B 2 100 GLY 100 100 100 GLY GLY L . n B 2 101 GLY 101 101 101 GLY GLY L . n B 2 102 THR 102 102 102 THR THR L . n B 2 103 LYS 103 103 103 LYS LYS L . n B 2 104 LEU 104 104 104 LEU LEU L . n B 2 105 GLU 105 105 105 GLU GLU L . n B 2 106 ILE 106 106 106 ILE ILE L . n B 2 107 LYS 107 107 107 LYS LYS L . n B 2 108 ARG 108 108 108 ARG ARG L . n B 2 109 ALA 109 109 109 ALA ALA L . n B 2 110 ASP 110 110 110 ASP ASP L . n B 2 111 ALA 111 111 111 ALA ALA L . n B 2 112 ALA 112 112 112 ALA ALA L . n B 2 113 PRO 113 113 113 PRO PRO L . n B 2 114 THR 114 114 114 THR THR L . n B 2 115 VAL 115 115 115 VAL VAL L . n B 2 116 SER 116 116 116 SER SER L . n B 2 117 ILE 117 117 117 ILE ILE L . n B 2 118 PHE 118 118 118 PHE PHE L . n B 2 119 PRO 119 119 119 PRO PRO L . n B 2 120 PRO 120 120 120 PRO PRO L . n B 2 121 SER 121 121 121 SER SER L . n B 2 122 SER 122 122 122 SER SER L . n B 2 123 GLU 123 123 123 GLU GLU L . n B 2 124 GLN 124 124 124 GLN GLN L . n B 2 125 LEU 125 125 125 LEU LEU L . n B 2 126 THR 126 126 126 THR THR L . n B 2 127 SER 127 127 127 SER SER L . n B 2 128 GLY 128 128 128 GLY GLY L . n B 2 129 GLY 129 129 129 GLY GLY L . n B 2 130 ALA 130 130 130 ALA ALA L . n B 2 131 SER 131 131 131 SER SER L . n B 2 132 VAL 132 132 132 VAL VAL L . n B 2 133 VAL 133 133 133 VAL VAL L . n B 2 134 CYS 134 134 134 CYS CYS L . n B 2 135 PHE 135 135 135 PHE PHE L . n B 2 136 LEU 136 136 136 LEU LEU L . n B 2 137 ASN 137 137 137 ASN ASN L . n B 2 138 ASN 138 138 138 ASN ASN L . n B 2 139 PHE 139 139 139 PHE PHE L . n B 2 140 TYR 140 140 140 TYR TYR L . n B 2 141 PRO 141 141 141 PRO PRO L . n B 2 142 LYS 142 142 142 LYS LYS L . n B 2 143 ASP 143 143 143 ASP ASP L . n B 2 144 ILE 144 144 144 ILE ILE L . n B 2 145 ASN 145 145 145 ASN ASN L . n B 2 146 VAL 146 146 146 VAL VAL L . n B 2 147 LYS 147 147 147 LYS LYS L . n B 2 148 TRP 148 148 148 TRP TRP L . n B 2 149 LYS 149 149 149 LYS LYS L . n B 2 150 ILE 150 150 150 ILE ILE L . n B 2 151 ASP 151 151 151 ASP ASP L . n B 2 152 GLY 152 152 152 GLY GLY L . n B 2 153 SER 153 153 153 SER SER L . n B 2 154 GLU 154 154 154 GLU GLU L . n B 2 155 ARG 155 155 155 ARG ARG L . n B 2 156 GLN 156 156 156 GLN GLN L . n B 2 157 ASN 157 157 157 ASN ASN L . n B 2 158 GLY 158 158 158 GLY GLY L . n B 2 159 VAL 159 159 159 VAL VAL L . n B 2 160 LEU 160 160 160 LEU LEU L . n B 2 161 ASN 161 161 161 ASN ASN L . n B 2 162 SER 162 162 162 SER SER L . n B 2 163 TRP 163 163 163 TRP TRP L . n B 2 164 THR 164 164 164 THR THR L . n B 2 165 ASP 165 165 165 ASP ASP L . n B 2 166 GLN 166 166 166 GLN GLN L . n B 2 167 ASP 167 167 167 ASP ASP L . n B 2 168 SER 168 168 168 SER SER L . n B 2 169 LYS 169 169 169 LYS LYS L . n B 2 170 ASP 170 170 170 ASP ASP L . n B 2 171 SER 171 171 171 SER SER L . n B 2 172 THR 172 172 172 THR THR L . n B 2 173 TYR 173 173 173 TYR TYR L . n B 2 174 SER 174 174 174 SER SER L . n B 2 175 MET 175 175 175 MET MET L . n B 2 176 SER 176 176 176 SER SER L . n B 2 177 SER 177 177 177 SER SER L . n B 2 178 THR 178 178 178 THR THR L . n B 2 179 LEU 179 179 179 LEU LEU L . n B 2 180 THR 180 180 180 THR THR L . n B 2 181 LEU 181 181 181 LEU LEU L . n B 2 182 THR 182 182 182 THR THR L . n B 2 183 LYS 183 183 183 LYS LYS L . n B 2 184 ASP 184 184 184 ASP ASP L . n B 2 185 GLU 185 185 185 GLU GLU L . n B 2 186 TYR 186 186 186 TYR TYR L . n B 2 187 GLU 187 187 187 GLU GLU L . n B 2 188 ARG 188 188 188 ARG ARG L . n B 2 189 HIS 189 189 189 HIS HIS L . n B 2 190 ASN 190 190 190 ASN ASN L . n B 2 191 SER 191 191 191 SER SER L . n B 2 192 TYR 192 192 192 TYR TYR L . n B 2 193 THR 193 193 193 THR THR L . n B 2 194 CYS 194 194 194 CYS CYS L . n B 2 195 GLU 195 195 195 GLU GLU L . n B 2 196 ALA 196 196 196 ALA ALA L . n B 2 197 THR 197 197 197 THR THR L . n B 2 198 HIS 198 198 198 HIS HIS L . n B 2 199 LYS 199 199 199 LYS LYS L . n B 2 200 THR 200 200 200 THR THR L . n B 2 201 SER 201 201 201 SER SER L . n B 2 202 THR 202 202 202 THR THR L . n B 2 203 SER 203 203 203 SER SER L . n B 2 204 PRO 204 204 204 PRO PRO L . n B 2 205 ILE 205 205 205 ILE ILE L . n B 2 206 VAL 206 206 206 VAL VAL L . n B 2 207 LYS 207 207 207 LYS LYS L . n B 2 208 SER 208 208 208 SER SER L . n B 2 209 PHE 209 209 209 PHE PHE L . n B 2 210 ASN 210 210 210 ASN ASN L . n B 2 211 ARG 211 211 211 ARG ARG L . n B 2 212 ASN 212 212 212 ASN ASN L . n B 2 213 GLU 213 213 213 GLU GLU L . n B 2 214 CYS 214 214 214 CYS CYS L . n C 3 1 GLN 1 1 1 GLN GLN H . n C 3 2 ILE 2 2 2 ILE ILE H . n C 3 3 GLN 3 3 3 GLN GLN H . n C 3 4 LEU 4 4 4 LEU LEU H . n C 3 5 VAL 5 5 5 VAL VAL H . n C 3 6 GLN 6 6 6 GLN GLN H . n C 3 7 SER 7 7 7 SER SER H . n C 3 8 GLY 8 8 8 GLY GLY H . n C 3 9 PRO 9 9 9 PRO PRO H . n C 3 10 GLU 10 10 10 GLU GLU H . n C 3 11 LEU 11 11 11 LEU LEU H . n C 3 12 LYS 12 12 12 LYS LYS H . n C 3 13 LYS 13 13 13 LYS LYS H . n C 3 14 PRO 14 14 14 PRO PRO H . n C 3 15 GLY 15 15 15 GLY GLY H . n C 3 16 GLU 16 16 16 GLU GLU H . n C 3 17 THR 17 17 17 THR THR H . n C 3 18 VAL 18 18 18 VAL VAL H . n C 3 19 LYS 19 19 19 LYS LYS H . n C 3 20 ILE 20 20 20 ILE ILE H . n C 3 21 SER 21 21 21 SER SER H . n C 3 22 CYS 22 22 22 CYS CYS H . n C 3 23 LYS 23 23 23 LYS LYS H . n C 3 24 ALA 24 24 24 ALA ALA H . n C 3 25 SER 25 25 25 SER SER H . n C 3 26 GLY 26 26 26 GLY GLY H . n C 3 27 TYR 27 27 27 TYR TYR H . n C 3 28 THR 28 28 28 THR THR H . n C 3 29 PHE 29 29 29 PHE PHE H . n C 3 30 THR 30 30 30 THR THR H . n C 3 31 ASN 31 31 31 ASN ASN H . n C 3 32 TYR 32 32 32 TYR TYR H . n C 3 33 GLY 33 33 33 GLY GLY H . n C 3 34 MET 34 34 34 MET MET H . n C 3 35 ASN 35 35 35 ASN ASN H . n C 3 36 TRP 36 36 36 TRP TRP H . n C 3 37 VAL 37 37 37 VAL VAL H . n C 3 38 LYS 38 38 38 LYS LYS H . n C 3 39 GLN 39 39 39 GLN GLN H . n C 3 40 ALA 40 40 40 ALA ALA H . n C 3 41 PRO 41 41 41 PRO PRO H . n C 3 42 GLY 42 42 42 GLY GLY H . n C 3 43 LYS 43 43 43 LYS LYS H . n C 3 44 GLY 44 44 44 GLY GLY H . n C 3 45 LEU 45 45 45 LEU LEU H . n C 3 46 GLU 46 46 46 GLU GLU H . n C 3 47 TRP 47 47 47 TRP TRP H . n C 3 48 MET 48 48 48 MET MET H . n C 3 49 GLY 49 49 49 GLY GLY H . n C 3 50 TRP 50 50 50 TRP TRP H . n C 3 51 ILE 51 51 51 ILE ILE H . n C 3 52 ASN 52 52 52 ASN ASN H . n C 3 53 THR 53 52 52 THR THR H A n C 3 54 ASN 54 53 53 ASN ASN H . n C 3 55 THR 55 54 54 THR THR H . n C 3 56 GLY 56 55 55 GLY GLY H . n C 3 57 GLU 57 56 56 GLU GLU H . n C 3 58 PRO 58 57 57 PRO PRO H . n C 3 59 THR 59 58 58 THR THR H . n C 3 60 TYR 60 59 59 TYR TYR H . n C 3 61 GLY 61 60 60 GLY GLY H . n C 3 62 GLU 62 61 61 GLU GLU H . n C 3 63 GLU 63 62 62 GLU GLU H . n C 3 64 PHE 64 63 63 PHE PHE H . n C 3 65 LYS 65 64 64 LYS LYS H . n C 3 66 GLY 66 65 65 GLY GLY H . n C 3 67 ARG 67 66 66 ARG ARG H . n C 3 68 PHE 68 67 67 PHE PHE H . n C 3 69 ALA 69 68 68 ALA ALA H . n C 3 70 PHE 70 69 69 PHE PHE H . n C 3 71 SER 71 70 70 SER SER H . n C 3 72 LEU 72 71 71 LEU LEU H . n C 3 73 GLU 73 72 72 GLU GLU H . n C 3 74 THR 74 73 73 THR THR H . n C 3 75 SER 75 74 74 SER SER H . n C 3 76 ALA 76 75 75 ALA ALA H . n C 3 77 SER 77 76 76 SER SER H . n C 3 78 THR 78 77 77 THR THR H . n C 3 79 ALA 79 78 78 ALA ALA H . n C 3 80 ASN 80 79 79 ASN ASN H . n C 3 81 LEU 81 80 80 LEU LEU H . n C 3 82 GLN 82 81 81 GLN GLN H . n C 3 83 ILE 83 82 82 ILE ILE H . n C 3 84 ASN 84 82 82 ASN ASN H A n C 3 85 ASN 85 82 82 ASN ASN H B n C 3 86 LEU 86 82 82 LEU LEU H C n C 3 87 LYS 87 83 83 LYS LYS H . n C 3 88 ASN 88 84 84 ASN ASN H . n C 3 89 GLU 89 85 85 GLU GLU H . n C 3 90 ASP 90 86 86 ASP ASP H . n C 3 91 LYS 91 87 87 LYS LYS H . n C 3 92 ALA 92 88 88 ALA ALA H . n C 3 93 THR 93 89 89 THR THR H . n C 3 94 PHE 94 90 90 PHE PHE H . n C 3 95 PHE 95 91 91 PHE PHE H . n C 3 96 CYS 96 92 92 CYS CYS H . n C 3 97 ALA 97 93 93 ALA ALA H . n C 3 98 ARG 98 94 94 ARG ARG H . n C 3 99 GLY 99 95 95 GLY GLY H . n C 3 100 GLU 100 96 96 GLU GLU H . n C 3 101 ASP 101 97 97 ASP ASP H . n C 3 102 ASN 102 98 98 ASN ASN H . n C 3 103 PHE 103 99 99 PHE PHE H . n C 3 104 GLY 104 100 100 GLY GLY H . n C 3 105 SER 105 100 100 SER SER H A n C 3 106 LEU 106 100 100 LEU LEU H B n C 3 107 SER 107 100 100 SER SER H C n C 3 108 ASP 108 101 101 ASP ASP H . n C 3 109 TYR 109 102 102 TYR TYR H . n C 3 110 TRP 110 103 103 TRP TRP H . n C 3 111 GLY 111 104 104 GLY GLY H . n C 3 112 GLN 112 105 105 GLN GLN H . n C 3 113 GLY 113 106 106 GLY GLY H . n C 3 114 THR 114 107 107 THR THR H . n C 3 115 THR 115 108 108 THR THR H . n C 3 116 LEU 116 109 109 LEU LEU H . n C 3 117 THR 117 110 110 THR THR H . n C 3 118 VAL 118 111 111 VAL VAL H . n C 3 119 SER 119 112 112 SER SER H . n C 3 120 SER 120 113 113 SER SER H . n C 3 121 ALA 121 114 114 ALA ALA H . n C 3 122 LYS 122 115 115 LYS LYS H . n C 3 123 THR 123 116 116 THR THR H . n C 3 124 THR 124 117 117 THR THR H . n C 3 125 ALA 125 118 118 ALA ALA H . n C 3 126 PRO 126 119 119 PRO PRO H . n C 3 127 SER 127 120 120 SER SER H . n C 3 128 VAL 128 121 121 VAL VAL H . n C 3 129 TYR 129 122 122 TYR TYR H . n C 3 130 PRO 130 123 123 PRO PRO H . n C 3 131 LEU 131 124 124 LEU LEU H . n C 3 132 ALA 132 125 125 ALA ALA H . n C 3 133 PRO 133 126 126 PRO PRO H . n C 3 134 VAL 134 127 127 VAL VAL H . n C 3 135 CYS 135 128 128 CYS CYS H . n C 3 136 GLY 136 129 129 GLY GLY H . n C 3 137 ASP 137 130 130 ASP ASP H . n C 3 138 THR 138 133 133 THR THR H . n C 3 139 THR 139 134 134 THR THR H . n C 3 140 GLY 140 135 135 GLY GLY H . n C 3 141 SER 141 136 136 SER SER H . n C 3 142 SER 142 137 137 SER SER H . n C 3 143 VAL 143 138 138 VAL VAL H . n C 3 144 THR 144 139 139 THR THR H . n C 3 145 LEU 145 140 140 LEU LEU H . n C 3 146 GLY 146 141 141 GLY GLY H . n C 3 147 CYS 147 142 142 CYS CYS H . n C 3 148 LEU 148 143 143 LEU LEU H . n C 3 149 VAL 149 144 144 VAL VAL H . n C 3 150 LYS 150 145 145 LYS LYS H . n C 3 151 GLY 151 146 146 GLY GLY H . n C 3 152 TYR 152 147 147 TYR TYR H . n C 3 153 PHE 153 148 148 PHE PHE H . n C 3 154 PRO 154 149 149 PRO PRO H . n C 3 155 GLU 155 150 150 GLU GLU H . n C 3 156 PRO 156 151 151 PRO PRO H . n C 3 157 VAL 157 152 152 VAL VAL H . n C 3 158 THR 158 153 153 THR THR H . n C 3 159 LEU 159 154 154 LEU LEU H . n C 3 160 THR 160 156 156 THR THR H . n C 3 161 TRP 161 157 157 TRP TRP H . n C 3 162 ASN 162 162 162 ASN ASN H . n C 3 163 SER 163 163 163 SER SER H . n C 3 164 GLY 164 164 164 GLY GLY H . n C 3 165 SER 165 165 165 SER SER H . n C 3 166 LEU 166 166 166 LEU LEU H . n C 3 167 SER 167 167 167 SER SER H . n C 3 168 SER 168 168 168 SER SER H . n C 3 169 GLY 169 169 169 GLY GLY H . n C 3 170 VAL 170 171 171 VAL VAL H . n C 3 171 HIS 171 172 172 HIS HIS H . n C 3 172 THR 172 173 173 THR THR H . n C 3 173 PHE 173 174 174 PHE PHE H . n C 3 174 PRO 174 175 175 PRO PRO H . n C 3 175 ALA 175 176 176 ALA ALA H . n C 3 176 VAL 176 177 177 VAL VAL H . n C 3 177 LEU 177 178 178 LEU LEU H . n C 3 178 GLN 178 179 179 GLN GLN H . n C 3 179 SER 179 180 180 SER SER H . n C 3 180 ASP 180 183 183 ASP ASP H . n C 3 181 LEU 181 184 184 LEU LEU H . n C 3 182 TYR 182 185 185 TYR TYR H . n C 3 183 THR 183 186 186 THR THR H . n C 3 184 LEU 184 187 187 LEU LEU H . n C 3 185 SER 185 188 188 SER SER H . n C 3 186 SER 186 189 189 SER SER H . n C 3 187 SER 187 190 190 SER SER H . n C 3 188 VAL 188 191 191 VAL VAL H . n C 3 189 THR 189 192 192 THR THR H . n C 3 190 VAL 190 193 193 VAL VAL H . n C 3 191 THR 191 194 194 THR THR H . n C 3 192 SER 192 195 195 SER SER H . n C 3 193 SER 193 196 196 SER SER H . n C 3 194 THR 194 198 198 THR THR H . n C 3 195 TRP 195 199 199 TRP TRP H . n C 3 196 PRO 196 200 200 PRO PRO H . n C 3 197 SER 197 202 202 SER SER H . n C 3 198 GLN 198 203 203 GLN GLN H . n C 3 199 SER 199 204 204 SER SER H . n C 3 200 ILE 200 205 205 ILE ILE H . n C 3 201 THR 201 206 206 THR THR H . n C 3 202 CYS 202 208 208 CYS CYS H . n C 3 203 ASN 203 209 209 ASN ASN H . n C 3 204 VAL 204 210 210 VAL VAL H . n C 3 205 ALA 205 211 211 ALA ALA H . n C 3 206 HIS 206 212 212 HIS HIS H . n C 3 207 PRO 207 213 213 PRO PRO H . n C 3 208 ALA 208 214 214 ALA ALA H . n C 3 209 SER 209 215 215 SER SER H . n C 3 210 SER 210 216 216 SER SER H . n C 3 211 THR 211 217 217 THR THR H . n C 3 212 LYS 212 218 218 LYS LYS H . n C 3 213 VAL 213 219 219 VAL VAL H . n C 3 214 ASP 214 220 220 ASP ASP H . n C 3 215 LYS 215 221 221 LYS LYS H . n C 3 216 LYS 216 222 222 LYS LYS H . n C 3 217 ILE 217 223 223 ILE ILE H . n C 3 218 GLU 218 224 224 GLU GLU H . n C 3 219 PRO 219 225 225 PRO PRO H . n C 3 220 ARG 220 226 226 ARG ARG H . n C 3 221 GLY 221 227 227 GLY GLY H . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code D 4 NAG 1 469 200 NAG NAG N A E 4 NAG 2 470 200 NAG NAG N B F 5 BMA 3 471 200 BMA MAN N C G 6 MAN 4 472 200 MAN MAN N D H 6 MAN 5 473 200 MAN MAN N E I 6 MAN 6 474 200 MAN MAN N F J 4 NAG 1 475 86 NAG NAG N A K 4 NAG 1 476 146 NAG NAG N A L 4 NAG 2 477 146 NAG NAG N B M 7 CA 1 0 0 CA CA N . N 8 HOH 1 478 53 HOH HOH N . N 8 HOH 2 479 103 HOH HOH N . N 8 HOH 3 480 104 HOH HOH N . N 8 HOH 4 481 108 HOH HOH N . N 8 HOH 5 482 110 HOH HOH N . N 8 HOH 6 483 120 HOH HOH N . N 8 HOH 7 484 131 HOH HOH N . N 8 HOH 8 485 148 HOH HOH N . N 8 HOH 9 486 203 HOH HOH N . N 8 HOH 10 487 204 HOH HOH N . N 8 HOH 11 488 205 HOH HOH N . N 8 HOH 12 489 206 HOH HOH N . N 8 HOH 13 490 207 HOH HOH N . N 8 HOH 14 491 211 HOH HOH N . N 8 HOH 15 492 212 HOH HOH N . N 8 HOH 16 493 213 HOH HOH N . N 8 HOH 17 494 217 HOH HOH N . N 8 HOH 18 495 224 HOH HOH N . N 8 HOH 19 496 226 HOH HOH N . N 8 HOH 20 497 228 HOH HOH N . N 8 HOH 21 498 229 HOH HOH N . N 8 HOH 22 499 231 HOH HOH N . N 8 HOH 23 500 232 HOH HOH N . N 8 HOH 24 501 235 HOH HOH N . N 8 HOH 25 502 236 HOH HOH N . N 8 HOH 26 503 237 HOH HOH N . N 8 HOH 27 504 241 HOH HOH N . N 8 HOH 28 505 242 HOH HOH N . N 8 HOH 29 506 243 HOH HOH N . N 8 HOH 30 507 250 HOH HOH N . N 8 HOH 31 508 251 HOH HOH N . N 8 HOH 32 509 253 HOH HOH N . N 8 HOH 33 510 254 HOH HOH N . N 8 HOH 34 511 256 HOH HOH N . N 8 HOH 35 512 259 HOH HOH N . N 8 HOH 36 513 261 HOH HOH N . N 8 HOH 37 514 263 HOH HOH N . N 8 HOH 38 515 266 HOH HOH N . N 8 HOH 39 516 268 HOH HOH N . N 8 HOH 40 517 269 HOH HOH N . N 8 HOH 41 518 270 HOH HOH N . N 8 HOH 42 519 271 HOH HOH N . N 8 HOH 43 520 274 HOH HOH N . N 8 HOH 44 521 275 HOH HOH N . N 8 HOH 45 522 276 HOH HOH N . N 8 HOH 46 523 277 HOH HOH N . N 8 HOH 47 524 278 HOH HOH N . N 8 HOH 48 525 280 HOH HOH N . N 8 HOH 49 526 281 HOH HOH N . N 8 HOH 50 527 283 HOH HOH N . N 8 HOH 51 528 284 HOH HOH N . N 8 HOH 52 529 286 HOH HOH N . N 8 HOH 53 530 289 HOH HOH N . N 8 HOH 54 531 290 HOH HOH N . N 8 HOH 55 532 291 HOH HOH N . N 8 HOH 56 533 292 HOH HOH N . N 8 HOH 57 534 293 HOH HOH N . N 8 HOH 58 535 295 HOH HOH N . N 8 HOH 59 536 298 HOH HOH N . N 8 HOH 60 537 299 HOH HOH N . N 8 HOH 61 538 301 HOH HOH N . N 8 HOH 62 539 302 HOH HOH N . N 8 HOH 63 540 311 HOH HOH N . O 8 HOH 1 215 1 HOH HOH L . O 8 HOH 2 216 86 HOH HOH L . P 8 HOH 1 228 14 HOH HOH H . P 8 HOH 2 229 15 HOH HOH H . P 8 HOH 3 230 66 HOH HOH H . P 8 HOH 4 231 113 HOH HOH H . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 6 N ASN 86 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 66 N ASN 146 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 121 N ASN 200 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details dodecameric _pdbx_struct_assembly.oligomeric_count 12 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1,2,3,4 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P # loop_ _pdbx_struct_oper_list.id _pdbx_struct_oper_list.type _pdbx_struct_oper_list.name _pdbx_struct_oper_list.symmetry_operation _pdbx_struct_oper_list.matrix[1][1] _pdbx_struct_oper_list.matrix[1][2] _pdbx_struct_oper_list.matrix[1][3] _pdbx_struct_oper_list.vector[1] _pdbx_struct_oper_list.matrix[2][1] _pdbx_struct_oper_list.matrix[2][2] _pdbx_struct_oper_list.matrix[2][3] _pdbx_struct_oper_list.vector[2] _pdbx_struct_oper_list.matrix[3][1] _pdbx_struct_oper_list.matrix[3][2] _pdbx_struct_oper_list.matrix[3][3] _pdbx_struct_oper_list.vector[3] 1 'identity operation' 1_555 x,y,z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 2 'crystal symmetry operation' 4_555 y+1/2,-x+1/2,z 0.0000000000 1.0000000000 0.0000000000 83.5000000000 -1.0000000000 0.0000000000 0.0000000000 83.5000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 3 'crystal symmetry operation' 3_545 -y+1/2,x-1/2,z 0.0000000000 -1.0000000000 0.0000000000 83.5000000000 1.0000000000 0.0000000000 0.0000000000 -83.5000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 4 'crystal symmetry operation' 2_655 -x+1,-y,z -1.0000000000 0.0000000000 0.0000000000 167.0000000000 0.0000000000 -1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 O ? A ASN 215 ? N ASN 294 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 OD2 ? A ASP 245 ? N ASP 324 ? 1_555 119.8 ? 2 O ? A ASN 215 ? N ASN 294 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A GLY 218 ? N GLY 297 ? 1_555 114.9 ? 3 OD2 ? A ASP 245 ? N ASP 324 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A GLY 218 ? N GLY 297 ? 1_555 72.4 ? 4 O ? A ASN 215 ? N ASN 294 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASP 214 ? N ASP 293 ? 1_555 56.6 ? 5 OD2 ? A ASP 245 ? N ASP 324 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASP 214 ? N ASP 293 ? 1_555 69.4 ? 6 O ? A GLY 218 ? N GLY 297 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASP 214 ? N ASP 293 ? 1_555 77.1 ? 7 O ? A ASN 215 ? N ASN 294 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASN 267 ? N ASN 347 ? 1_555 67.8 ? 8 OD2 ? A ASP 245 ? N ASP 324 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASN 267 ? N ASN 347 ? 1_555 90.7 ? 9 O ? A GLY 218 ? N GLY 297 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASN 267 ? N ASN 347 ? 1_555 162.1 ? 10 O ? A ASP 214 ? N ASP 293 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASN 267 ? N ASN 347 ? 1_555 91.5 ? 11 O ? A ASN 215 ? N ASN 294 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASN 264 ? N ASN 344 ? 1_555 94.2 ? 12 OD2 ? A ASP 245 ? N ASP 324 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASN 264 ? N ASN 344 ? 1_555 145.6 ? 13 O ? A GLY 218 ? N GLY 297 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASN 264 ? N ASN 344 ? 1_555 99.8 ? 14 O ? A ASP 214 ? N ASP 293 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASN 264 ? N ASN 344 ? 1_555 143.1 ? 15 O ? A ASN 267 ? N ASN 347 ? 1_555 CA ? M CA . ? N CA 0 ? 1_555 O ? A ASN 264 ? N ASN 344 ? 1_555 97.5 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 1994-01-31 2 'Structure model' 1 1 2008-03-24 3 'Structure model' 1 2 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Source and taxonomy' 3 3 'Structure model' 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal X-PLOR 'model building' . ? 1 X-PLOR refinement . ? 2 X-PLOR phasing . ? 3 # _pdbx_entry_details.entry_id 1NCD _pdbx_entry_details.compound_details ? _pdbx_entry_details.source_details ? _pdbx_entry_details.nonpolymer_details ? _pdbx_entry_details.sequence_details ;THE SEQUENCE OF THE FOLLOWING RESIDUES DIFFERS FROM THE CHEMICAL SEQUENCE: LYS H 46 WAS REFINED AS GLU THR H 87 WAS REFINED AS LYS VAL H 109 WAS REFINED AS LEU SER N 81 WAS REFINED AS ILE ; # loop_ _pdbx_validate_rmsd_bond.id _pdbx_validate_rmsd_bond.PDB_model_num _pdbx_validate_rmsd_bond.auth_atom_id_1 _pdbx_validate_rmsd_bond.auth_asym_id_1 _pdbx_validate_rmsd_bond.auth_comp_id_1 _pdbx_validate_rmsd_bond.auth_seq_id_1 _pdbx_validate_rmsd_bond.PDB_ins_code_1 _pdbx_validate_rmsd_bond.label_alt_id_1 _pdbx_validate_rmsd_bond.auth_atom_id_2 _pdbx_validate_rmsd_bond.auth_asym_id_2 _pdbx_validate_rmsd_bond.auth_comp_id_2 _pdbx_validate_rmsd_bond.auth_seq_id_2 _pdbx_validate_rmsd_bond.PDB_ins_code_2 _pdbx_validate_rmsd_bond.label_alt_id_2 _pdbx_validate_rmsd_bond.bond_value _pdbx_validate_rmsd_bond.bond_target_value _pdbx_validate_rmsd_bond.bond_deviation _pdbx_validate_rmsd_bond.bond_standard_deviation _pdbx_validate_rmsd_bond.linker_flag 1 1 NE2 N HIS 144 ? ? CD2 N HIS 144 ? ? 1.297 1.373 -0.076 0.011 N 2 1 NE2 N HIS 150 ? ? CD2 N HIS 150 ? ? 1.302 1.373 -0.071 0.011 N 3 1 NE2 N HIS 184 ? ? CD2 N HIS 184 ? ? 1.295 1.373 -0.078 0.011 N 4 1 NE2 N HIS 274 ? ? CD2 N HIS 274 ? ? 1.305 1.373 -0.068 0.011 N 5 1 NE2 N HIS 312 ? ? CD2 N HIS 312 ? ? 1.301 1.373 -0.072 0.011 N 6 1 NE2 L HIS 91 ? ? CD2 L HIS 91 ? ? 1.286 1.373 -0.087 0.011 N 7 1 NE2 L HIS 198 ? ? CD2 L HIS 198 ? ? 1.300 1.373 -0.073 0.011 N 8 1 NE2 H HIS 172 ? ? CD2 H HIS 172 ? ? 1.306 1.373 -0.067 0.011 N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CD1 N TRP 97 ? ? CG N TRP 97 ? ? CD2 N TRP 97 ? ? 112.55 106.30 6.25 0.80 N 2 1 CB N TRP 97 ? ? CG N TRP 97 ? ? CD1 N TRP 97 ? ? 118.96 127.00 -8.04 1.30 N 3 1 CE2 N TRP 97 ? ? CD2 N TRP 97 ? ? CG N TRP 97 ? ? 100.96 107.30 -6.34 0.80 N 4 1 CG N TRP 97 ? ? CD2 N TRP 97 ? ? CE3 N TRP 97 ? ? 140.61 133.90 6.71 0.90 N 5 1 CB N ILE 99 ? ? CA N ILE 99 ? ? C N ILE 99 ? ? 99.54 111.60 -12.06 2.00 N 6 1 CB N TYR 100 ? ? CG N TYR 100 ? ? CD2 N TYR 100 ? ? 116.33 121.00 -4.67 0.60 N 7 1 NE N ARG 107 ? ? CZ N ARG 107 ? ? NH1 N ARG 107 ? ? 125.43 120.30 5.13 0.50 N 8 1 NE N ARG 118 ? ? CZ N ARG 118 ? ? NH1 N ARG 118 ? ? 124.52 120.30 4.22 0.50 N 9 1 CG N GLN 136 ? ? CD N GLN 136 ? ? NE2 N GLN 136 ? ? 132.93 116.70 16.23 2.40 N 10 1 NE N ARG 141 ? ? CZ N ARG 141 ? ? NH1 N ARG 141 ? ? 124.57 120.30 4.27 0.50 N 11 1 NE N ARG 156 ? ? CZ N ARG 156 ? ? NH1 N ARG 156 ? ? 124.49 120.30 4.19 0.50 N 12 1 NE N ARG 156 ? ? CZ N ARG 156 ? ? NH2 N ARG 156 ? ? 115.77 120.30 -4.53 0.50 N 13 1 CA N ASP 157 ? ? CB N ASP 157 ? ? CG N ASP 157 ? ? 126.95 113.40 13.55 2.20 N 14 1 CD1 N TRP 161 ? ? CG N TRP 161 ? ? CD2 N TRP 161 ? ? 112.52 106.30 6.22 0.80 N 15 1 CB N TRP 161 ? ? CG N TRP 161 ? ? CD1 N TRP 161 ? ? 118.97 127.00 -8.03 1.30 N 16 1 CE2 N TRP 161 ? ? CD2 N TRP 161 ? ? CG N TRP 161 ? ? 100.93 107.30 -6.37 0.80 N 17 1 CG N TRP 161 ? ? CD2 N TRP 161 ? ? CE3 N TRP 161 ? ? 140.13 133.90 6.23 0.90 N 18 1 NE N ARG 172 ? ? CZ N ARG 172 ? ? NH1 N ARG 172 ? ? 123.65 120.30 3.35 0.50 N 19 1 CA N CYS 175 ? ? CB N CYS 175 ? ? SG N CYS 175 ? ? 120.97 114.20 6.77 1.10 N 20 1 CD1 N TRP 178 ? ? CG N TRP 178 ? ? CD2 N TRP 178 ? ? 112.04 106.30 5.74 0.80 N 21 1 CE2 N TRP 178 ? ? CD2 N TRP 178 ? ? CG N TRP 178 ? ? 100.82 107.30 -6.48 0.80 N 22 1 CD1 N TRP 206 ? ? CG N TRP 206 ? ? CD2 N TRP 206 ? ? 112.63 106.30 6.33 0.80 N 23 1 CE2 N TRP 206 ? ? CD2 N TRP 206 ? ? CG N TRP 206 ? ? 101.84 107.30 -5.46 0.80 N 24 1 NE N ARG 210 ? ? CZ N ARG 210 ? ? NH2 N ARG 210 ? ? 115.47 120.30 -4.83 0.50 N 25 1 CD1 N TRP 218 ? ? CG N TRP 218 ? ? CD2 N TRP 218 ? ? 112.97 106.30 6.67 0.80 N 26 1 CE2 N TRP 218 ? ? CD2 N TRP 218 ? ? CG N TRP 218 ? ? 101.12 107.30 -6.18 0.80 N 27 1 NE N ARG 224 ? ? CZ N ARG 224 ? ? NH1 N ARG 224 ? ? 125.45 120.30 5.15 0.50 N 28 1 N N GLN 226 ? ? CA N GLN 226 ? ? C N GLN 226 ? ? 128.79 111.00 17.79 2.70 N 29 1 NE N ARG 253 ? ? CZ N ARG 253 ? ? NH2 N ARG 253 ? ? 116.84 120.30 -3.46 0.50 N 30 1 CD1 N TRP 265 ? ? CG N TRP 265 ? ? CD2 N TRP 265 ? ? 112.84 106.30 6.54 0.80 N 31 1 CG N TRP 265 ? ? CD1 N TRP 265 ? ? NE1 N TRP 265 ? ? 103.58 110.10 -6.52 1.00 N 32 1 CE2 N TRP 265 ? ? CD2 N TRP 265 ? ? CG N TRP 265 ? ? 102.17 107.30 -5.13 0.80 N 33 1 CB N TYR 281 ? ? CG N TYR 281 ? ? CD2 N TYR 281 ? ? 115.91 121.00 -5.09 0.60 N 34 1 NE N ARG 292 ? ? CZ N ARG 292 ? ? NH1 N ARG 292 ? ? 124.35 120.30 4.05 0.50 N 35 1 CD1 N TRP 295 ? ? CG N TRP 295 ? ? CD2 N TRP 295 ? ? 112.36 106.30 6.06 0.80 N 36 1 CE2 N TRP 295 ? ? CD2 N TRP 295 ? ? CG N TRP 295 ? ? 101.73 107.30 -5.57 0.80 N 37 1 CG N TRP 295 ? ? CD2 N TRP 295 ? ? CE3 N TRP 295 ? ? 139.58 133.90 5.68 0.90 N 38 1 CA N GLY 297 ? ? C N GLY 297 ? ? N N SER 298 ? ? 100.91 117.20 -16.29 2.20 Y 39 1 NE N ARG 300 ? ? CZ N ARG 300 ? ? NH1 N ARG 300 ? ? 125.23 120.30 4.93 0.50 N 40 1 NE N ARG 300 ? ? CZ N ARG 300 ? ? NH2 N ARG 300 ? ? 115.87 120.30 -4.43 0.50 N 41 1 NE N ARG 327 ? ? CZ N ARG 327 ? ? NH1 N ARG 327 ? ? 124.51 120.30 4.21 0.50 N 42 1 CD1 N TRP 361 ? ? CG N TRP 361 ? ? CD2 N TRP 361 ? ? 112.10 106.30 5.80 0.80 N 43 1 CE2 N TRP 361 ? ? CD2 N TRP 361 ? ? CG N TRP 361 ? ? 101.94 107.30 -5.36 0.80 N 44 1 NE N ARG 364 ? ? CZ N ARG 364 ? ? NH1 N ARG 364 ? ? 124.74 120.30 4.44 0.50 N 45 1 NE N ARG 387 ? ? CZ N ARG 387 ? ? NH1 N ARG 387 ? ? 123.47 120.30 3.17 0.50 N 46 1 CD1 N TRP 403 ? ? CG N TRP 403 ? ? CD2 N TRP 403 ? ? 112.48 106.30 6.18 0.80 N 47 1 CB N TRP 403 ? ? CG N TRP 403 ? ? CD1 N TRP 403 ? ? 117.49 127.00 -9.51 1.30 N 48 1 CE2 N TRP 403 ? ? CD2 N TRP 403 ? ? CG N TRP 403 ? ? 101.19 107.30 -6.11 0.80 N 49 1 CG N TRP 403 ? ? CD2 N TRP 403 ? ? CE3 N TRP 403 ? ? 140.61 133.90 6.71 0.90 N 50 1 CB N TYR 406 ? ? CG N TYR 406 ? ? CD2 N TYR 406 ? ? 117.00 121.00 -4.00 0.60 N 51 1 CD1 N TRP 412 B ? CG N TRP 412 B ? CD2 N TRP 412 B ? 112.46 106.30 6.16 0.80 N 52 1 CE2 N TRP 412 B ? CD2 N TRP 412 B ? CG N TRP 412 B ? 100.34 107.30 -6.96 0.80 N 53 1 CG N TRP 412 B ? CD2 N TRP 412 B ? CE3 N TRP 412 B ? 139.36 133.90 5.46 0.90 N 54 1 CD1 N TRP 437 ? ? CG N TRP 437 ? ? CD2 N TRP 437 ? ? 111.15 106.30 4.85 0.80 N 55 1 CE2 N TRP 437 ? ? CD2 N TRP 437 ? ? CG N TRP 437 ? ? 101.66 107.30 -5.64 0.80 N 56 1 CG N TRP 437 ? ? CD2 N TRP 437 ? ? CE3 N TRP 437 ? ? 140.08 133.90 6.18 0.90 N 57 1 CD1 N TRP 438 ? ? CG N TRP 438 ? ? CD2 N TRP 438 ? ? 113.44 106.30 7.14 0.80 N 58 1 CB N TRP 438 ? ? CG N TRP 438 ? ? CD1 N TRP 438 ? ? 115.95 127.00 -11.05 1.30 N 59 1 CG N TRP 438 ? ? CD1 N TRP 438 ? ? NE1 N TRP 438 ? ? 103.99 110.10 -6.11 1.00 N 60 1 CE2 N TRP 438 ? ? CD2 N TRP 438 ? ? CG N TRP 438 ? ? 100.48 107.30 -6.82 0.80 N 61 1 CG N TRP 438 ? ? CD2 N TRP 438 ? ? CE3 N TRP 438 ? ? 142.45 133.90 8.55 0.90 N 62 1 CG N MET 446 ? ? SD N MET 446 ? ? CE N MET 446 ? ? 86.92 100.20 -13.28 1.60 N 63 1 CD1 N TRP 456 ? ? CG N TRP 456 ? ? CD2 N TRP 456 ? ? 112.44 106.30 6.14 0.80 N 64 1 CE2 N TRP 456 ? ? CD2 N TRP 456 ? ? CG N TRP 456 ? ? 100.45 107.30 -6.85 0.80 N 65 1 CG N TRP 456 ? ? CD2 N TRP 456 ? ? CE3 N TRP 456 ? ? 141.90 133.90 8.00 0.90 N 66 1 CA L MET 11 ? ? CB L MET 11 ? ? CG L MET 11 ? ? 100.41 113.30 -12.89 1.70 N 67 1 CD1 L TRP 35 ? ? CG L TRP 35 ? ? CD2 L TRP 35 ? ? 111.96 106.30 5.66 0.80 N 68 1 CE2 L TRP 35 ? ? CD2 L TRP 35 ? ? CG L TRP 35 ? ? 101.44 107.30 -5.86 0.80 N 69 1 CD1 L TRP 50 ? ? CG L TRP 50 ? ? CD2 L TRP 50 ? ? 112.53 106.30 6.23 0.80 N 70 1 CE2 L TRP 50 ? ? CD2 L TRP 50 ? ? CG L TRP 50 ? ? 101.47 107.30 -5.83 0.80 N 71 1 NE L ARG 54 ? ? CZ L ARG 54 ? ? NH1 L ARG 54 ? ? 124.81 120.30 4.51 0.50 N 72 1 NE L ARG 54 ? ? CZ L ARG 54 ? ? NH2 L ARG 54 ? ? 113.29 120.30 -7.01 0.50 N 73 1 NE L ARG 61 ? ? CZ L ARG 61 ? ? NH1 L ARG 61 ? ? 124.01 120.30 3.71 0.50 N 74 1 NE L ARG 61 ? ? CZ L ARG 61 ? ? NH2 L ARG 61 ? ? 116.73 120.30 -3.57 0.50 N 75 1 CA L HIS 91 ? ? CB L HIS 91 ? ? CG L HIS 91 ? ? 123.86 113.60 10.26 1.70 N 76 1 CD1 L TRP 96 ? ? CG L TRP 96 ? ? CD2 L TRP 96 ? ? 111.19 106.30 4.89 0.80 N 77 1 CE2 L TRP 96 ? ? CD2 L TRP 96 ? ? CG L TRP 96 ? ? 101.99 107.30 -5.31 0.80 N 78 1 CD1 L TRP 148 ? ? CG L TRP 148 ? ? CD2 L TRP 148 ? ? 113.45 106.30 7.15 0.80 N 79 1 CE2 L TRP 148 ? ? CD2 L TRP 148 ? ? CG L TRP 148 ? ? 101.32 107.30 -5.98 0.80 N 80 1 NE L ARG 155 ? ? CZ L ARG 155 ? ? NH2 L ARG 155 ? ? 116.74 120.30 -3.56 0.50 N 81 1 CD1 L TRP 163 ? ? CG L TRP 163 ? ? CD2 L TRP 163 ? ? 112.71 106.30 6.41 0.80 N 82 1 CE2 L TRP 163 ? ? CD2 L TRP 163 ? ? CG L TRP 163 ? ? 101.61 107.30 -5.69 0.80 N 83 1 CG L TRP 163 ? ? CD2 L TRP 163 ? ? CE3 L TRP 163 ? ? 139.46 133.90 5.56 0.90 N 84 1 CB H TYR 27 ? ? CG H TYR 27 ? ? CD2 H TYR 27 ? ? 116.16 121.00 -4.84 0.60 N 85 1 CD1 H TRP 36 ? ? CG H TRP 36 ? ? CD2 H TRP 36 ? ? 111.88 106.30 5.58 0.80 N 86 1 CE2 H TRP 36 ? ? CD2 H TRP 36 ? ? CG H TRP 36 ? ? 102.29 107.30 -5.01 0.80 N 87 1 CE2 H TRP 47 ? ? CD2 H TRP 47 ? ? CG H TRP 47 ? ? 102.49 107.30 -4.81 0.80 N 88 1 CD1 H TRP 50 ? ? CG H TRP 50 ? ? CD2 H TRP 50 ? ? 112.68 106.30 6.38 0.80 N 89 1 CE2 H TRP 50 ? ? CD2 H TRP 50 ? ? CG H TRP 50 ? ? 101.94 107.30 -5.36 0.80 N 90 1 CB H TYR 59 ? ? CG H TYR 59 ? ? CD1 H TYR 59 ? ? 117.30 121.00 -3.70 0.60 N 91 1 CD1 H TRP 103 ? ? CG H TRP 103 ? ? CD2 H TRP 103 ? ? 113.39 106.30 7.09 0.80 N 92 1 CE2 H TRP 103 ? ? CD2 H TRP 103 ? ? CG H TRP 103 ? ? 101.39 107.30 -5.91 0.80 N 93 1 CA H CYS 128 ? ? CB H CYS 128 ? ? SG H CYS 128 ? ? 121.69 114.20 7.49 1.10 N 94 1 CD1 H TRP 157 ? ? CG H TRP 157 ? ? CD2 H TRP 157 ? ? 113.24 106.30 6.94 0.80 N 95 1 CE2 H TRP 157 ? ? CD2 H TRP 157 ? ? CG H TRP 157 ? ? 101.25 107.30 -6.05 0.80 N 96 1 CA H TRP 157 ? ? C H TRP 157 ? ? N H ASN 162 ? ? 103.68 117.20 -13.52 2.20 Y 97 1 CD1 H TRP 199 ? ? CG H TRP 199 ? ? CD2 H TRP 199 ? ? 111.29 106.30 4.99 0.80 N 98 1 CE2 H TRP 199 ? ? CD2 H TRP 199 ? ? CG H TRP 199 ? ? 102.13 107.30 -5.17 0.80 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 SER N 96 ? ? -170.11 -169.58 2 1 ARG N 118 ? ? 178.12 159.45 3 1 GLU N 119 ? ? 56.05 82.60 4 1 PRO N 167 ? ? -66.34 92.30 5 1 ASN N 170 ? ? -152.77 3.18 6 1 CYS N 175 ? ? 174.83 174.31 7 1 CYS N 183 ? ? -172.25 149.63 8 1 ARG N 187 ? ? -105.12 -66.60 9 1 ASN N 200 ? ? -154.13 46.84 10 1 ARG N 220 ? ? 46.74 25.34 11 1 ILE N 222 ? ? 45.21 102.28 12 1 GLN N 226 ? ? -27.03 -55.68 13 1 GLU N 251 ? ? -119.49 78.21 14 1 GLU N 277 ? ? 31.66 63.61 15 1 CYS N 291 ? ? -114.79 -150.09 16 1 TRP N 295 ? ? -35.46 -97.83 17 1 VAL N 321 ? ? -68.84 98.44 18 1 PRO N 331 ? ? -66.08 -168.69 19 1 ASP N 356 ? ? -151.79 50.47 20 1 ASN N 359 ? ? -102.67 50.93 21 1 ASP N 386 ? ? -78.58 23.66 22 1 SER N 404 ? ? -128.39 -135.39 23 1 SER N 442 ? ? -123.94 -169.72 24 1 ILE N 464 ? ? -54.38 -6.73 25 1 SER L 30 ? ? 36.08 49.02 26 1 THR L 31 ? ? 71.23 -0.16 27 1 ALA L 51 ? ? 71.47 -44.46 28 1 ASP L 60 ? ? -37.16 -0.89 29 1 HIS L 91 ? ? -140.82 35.56 30 1 PRO L 141 ? ? -50.37 175.14 31 1 SER L 168 ? ? -98.70 32.69 32 1 LYS L 169 ? ? -137.92 -93.51 33 1 ASN L 190 ? ? -148.44 -50.47 34 1 THR L 200 ? ? -67.85 1.72 35 1 THR L 202 ? ? -135.82 -60.30 36 1 ASN L 210 ? ? 178.28 141.93 37 1 TYR H 27 ? ? -112.93 -168.61 38 1 LYS H 43 ? ? -171.95 -26.65 39 1 GLU H 62 ? ? -62.28 5.29 40 1 ASN H 82 B ? 42.59 74.67 41 1 GLU H 85 ? ? -63.86 6.12 42 1 ALA H 88 ? ? -165.55 -169.19 43 1 PHE H 99 ? ? 81.62 -11.46 44 1 TYR H 102 ? ? 56.90 99.22 45 1 CYS H 128 ? ? 43.42 -117.35 46 1 THR H 134 ? ? 72.35 -165.17 47 1 SER H 180 ? ? 56.76 -74.45 48 1 SER H 216 ? ? 92.23 64.79 49 1 PRO H 225 ? ? -67.42 2.84 50 1 ARG H 226 ? ? -20.06 79.01 # loop_ _pdbx_validate_peptide_omega.id _pdbx_validate_peptide_omega.PDB_model_num _pdbx_validate_peptide_omega.auth_comp_id_1 _pdbx_validate_peptide_omega.auth_asym_id_1 _pdbx_validate_peptide_omega.auth_seq_id_1 _pdbx_validate_peptide_omega.PDB_ins_code_1 _pdbx_validate_peptide_omega.label_alt_id_1 _pdbx_validate_peptide_omega.auth_comp_id_2 _pdbx_validate_peptide_omega.auth_asym_id_2 _pdbx_validate_peptide_omega.auth_seq_id_2 _pdbx_validate_peptide_omega.PDB_ins_code_2 _pdbx_validate_peptide_omega.label_alt_id_2 _pdbx_validate_peptide_omega.omega 1 1 GLY N 196 ? ? PRO N 197 ? ? 149.64 2 1 GLY N 248 ? ? PRO N 249 ? ? 144.28 # _pdbx_validate_planes.id 1 _pdbx_validate_planes.PDB_model_num 1 _pdbx_validate_planes.auth_comp_id TYR _pdbx_validate_planes.auth_asym_id L _pdbx_validate_planes.auth_seq_id 140 _pdbx_validate_planes.PDB_ins_code ? _pdbx_validate_planes.label_alt_id ? _pdbx_validate_planes.rmsd 0.068 _pdbx_validate_planes.type 'SIDE CHAIN' # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 4 N-ACETYL-D-GLUCOSAMINE NAG 5 BETA-D-MANNOSE BMA 6 ALPHA-D-MANNOSE MAN 7 'CALCIUM ION' CA 8 water HOH #