data_1IGF # _entry.id 1IGF # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 1IGF WWPDB D_1000174149 # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 1IGF _pdbx_database_status.recvd_initial_deposition_date 1991-03-21 _pdbx_database_status.deposit_site ? _pdbx_database_status.process_site ? _pdbx_database_status.SG_entry . _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_mr ? _pdbx_database_status.status_code_sf ? _pdbx_database_status.status_code_cs ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Stanfield, R.L.' 1 'Wilson, I.A.' 2 # loop_ _citation.id _citation.title _citation.journal_abbrev _citation.journal_volume _citation.page_first _citation.page_last _citation.year _citation.journal_id_ASTM _citation.country _citation.journal_id_ISSN _citation.journal_id_CSD _citation.book_publisher _citation.pdbx_database_id_PubMed _citation.pdbx_database_id_DOI primary 'Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A.' Science 248 712 719 1990 SCIEAS US 0036-8075 0038 ? 2333521 ? 1 ;Preliminary Crystallographic Data and Primary Sequence for Anti-Peptide Fab' B13I2 and its Complex with the C-Helix Peptide from Myohemerythrin ; J.Biol.Chem. 264 15721 ? 1989 JBCHA3 US 0021-9258 0071 ? ? ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Stanfield, R.L.' 1 primary 'Fieser, T.M.' 2 primary 'Lerner, R.A.' 3 primary 'Wilson, I.A.' 4 1 'Stura, E.A.' 5 1 'Stanfield, R.L.' 6 1 'Fieser, T.M.' 7 1 'Balderas, R.S.' 8 1 'Smith, L.R.' 9 1 'Lerner, R.A.' 10 1 'Wilson, I.A.' 11 # _cell.entry_id 1IGF _cell.length_a 98.000 _cell.length_b 151.700 _cell.length_c 80.800 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 8 _cell.pdbx_unique_axis ? # _symmetry.entry_id 1IGF _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 19 # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'IGG1-KAPPA B13I2 FAB (LIGHT CHAIN)' 24148.803 2 ? ? ? ? 2 polymer man 'IGG1-KAPPA B13I2 FAB (HEAVY CHAIN)' 23807.738 2 ? ? ? ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;DVLMTQTPLSLPVSLGDQASISCRSNQTILLSDGDTYLEWYLQKPGQSPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKI SRVEAEDLGVYYCFQGSHVPPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSER QNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC ; ;DVLMTQTPLSLPVSLGDQASISCRSNQTILLSDGDTYLEWYLQKPGQSPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKI SRVEAEDLGVYYCFQGSHVPPTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSER QNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC ; L,M ? 2 'polypeptide(L)' no no ;EVQLVESGGDLVKPGGSLKLSCAASGFTFSRCAMSWVRQTPEKRLEWVAGISSGGSYTFYPDTVKGRFIISRNNARNTLS LQMSSLRSEDTAIYYCTRYSSDPFYFDYWGQGTTLTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTW NSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTCNVAHPASSTKVDKKIVPRDC ; ;EVQLVESGGDLVKPGGSLKLSCAASGFTFSRCAMSWVRQTPEKRLEWVAGISSGGSYTFYPDTVKGRFIISRNNARNTLS LQMSSLRSEDTAIYYCTRYSSDPFYFDYWGQGTTLTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTW NSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTCNVAHPASSTKVDKKIVPRDC ; H,J ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ASP n 1 2 VAL n 1 3 LEU n 1 4 MET n 1 5 THR n 1 6 GLN n 1 7 THR n 1 8 PRO n 1 9 LEU n 1 10 SER n 1 11 LEU n 1 12 PRO n 1 13 VAL n 1 14 SER n 1 15 LEU n 1 16 GLY n 1 17 ASP n 1 18 GLN n 1 19 ALA n 1 20 SER n 1 21 ILE n 1 22 SER n 1 23 CYS n 1 24 ARG n 1 25 SER n 1 26 ASN n 1 27 GLN n 1 28 THR n 1 29 ILE n 1 30 LEU n 1 31 LEU n 1 32 SER n 1 33 ASP n 1 34 GLY n 1 35 ASP n 1 36 THR n 1 37 TYR n 1 38 LEU n 1 39 GLU n 1 40 TRP n 1 41 TYR n 1 42 LEU n 1 43 GLN n 1 44 LYS n 1 45 PRO n 1 46 GLY n 1 47 GLN n 1 48 SER n 1 49 PRO n 1 50 LYS n 1 51 LEU n 1 52 LEU n 1 53 ILE n 1 54 TYR n 1 55 LYS n 1 56 VAL n 1 57 SER n 1 58 ASN n 1 59 ARG n 1 60 PHE n 1 61 SER n 1 62 GLY n 1 63 VAL n 1 64 PRO n 1 65 ASP n 1 66 ARG n 1 67 PHE n 1 68 SER n 1 69 GLY n 1 70 SER n 1 71 GLY n 1 72 SER n 1 73 GLY n 1 74 THR n 1 75 ASP n 1 76 PHE n 1 77 THR n 1 78 LEU n 1 79 LYS n 1 80 ILE n 1 81 SER n 1 82 ARG n 1 83 VAL n 1 84 GLU n 1 85 ALA n 1 86 GLU n 1 87 ASP n 1 88 LEU n 1 89 GLY n 1 90 VAL n 1 91 TYR n 1 92 TYR n 1 93 CYS n 1 94 PHE n 1 95 GLN n 1 96 GLY n 1 97 SER n 1 98 HIS n 1 99 VAL n 1 100 PRO n 1 101 PRO n 1 102 THR n 1 103 PHE n 1 104 GLY n 1 105 GLY n 1 106 GLY n 1 107 THR n 1 108 LYS n 1 109 LEU n 1 110 GLU n 1 111 ILE n 1 112 LYS n 1 113 ARG n 1 114 ALA n 1 115 ASP n 1 116 ALA n 1 117 ALA n 1 118 PRO n 1 119 THR n 1 120 VAL n 1 121 SER n 1 122 ILE n 1 123 PHE n 1 124 PRO n 1 125 PRO n 1 126 SER n 1 127 SER n 1 128 GLU n 1 129 GLN n 1 130 LEU n 1 131 THR n 1 132 SER n 1 133 GLY n 1 134 GLY n 1 135 ALA n 1 136 SER n 1 137 VAL n 1 138 VAL n 1 139 CYS n 1 140 PHE n 1 141 LEU n 1 142 ASN n 1 143 ASN n 1 144 PHE n 1 145 TYR n 1 146 PRO n 1 147 LYS n 1 148 ASP n 1 149 ILE n 1 150 ASN n 1 151 VAL n 1 152 LYS n 1 153 TRP n 1 154 LYS n 1 155 ILE n 1 156 ASP n 1 157 GLY n 1 158 SER n 1 159 GLU n 1 160 ARG n 1 161 GLN n 1 162 ASN n 1 163 GLY n 1 164 VAL n 1 165 LEU n 1 166 ASN n 1 167 SER n 1 168 TRP n 1 169 THR n 1 170 ASP n 1 171 GLN n 1 172 ASP n 1 173 SER n 1 174 LYS n 1 175 ASP n 1 176 SER n 1 177 THR n 1 178 TYR n 1 179 SER n 1 180 MET n 1 181 SER n 1 182 SER n 1 183 THR n 1 184 LEU n 1 185 THR n 1 186 LEU n 1 187 THR n 1 188 LYS n 1 189 ASP n 1 190 GLU n 1 191 TYR n 1 192 GLU n 1 193 ARG n 1 194 HIS n 1 195 ASN n 1 196 SER n 1 197 TYR n 1 198 THR n 1 199 CYS n 1 200 GLU n 1 201 ALA n 1 202 THR n 1 203 HIS n 1 204 LYS n 1 205 THR n 1 206 SER n 1 207 THR n 1 208 SER n 1 209 PRO n 1 210 ILE n 1 211 VAL n 1 212 LYS n 1 213 SER n 1 214 PHE n 1 215 ASN n 1 216 ARG n 1 217 ASN n 1 218 GLU n 1 219 CYS n 2 1 GLU n 2 2 VAL n 2 3 GLN n 2 4 LEU n 2 5 VAL n 2 6 GLU n 2 7 SER n 2 8 GLY n 2 9 GLY n 2 10 ASP n 2 11 LEU n 2 12 VAL n 2 13 LYS n 2 14 PRO n 2 15 GLY n 2 16 GLY n 2 17 SER n 2 18 LEU n 2 19 LYS n 2 20 LEU n 2 21 SER n 2 22 CYS n 2 23 ALA n 2 24 ALA n 2 25 SER n 2 26 GLY n 2 27 PHE n 2 28 THR n 2 29 PHE n 2 30 SER n 2 31 ARG n 2 32 CYS n 2 33 ALA n 2 34 MET n 2 35 SER n 2 36 TRP n 2 37 VAL n 2 38 ARG n 2 39 GLN n 2 40 THR n 2 41 PRO n 2 42 GLU n 2 43 LYS n 2 44 ARG n 2 45 LEU n 2 46 GLU n 2 47 TRP n 2 48 VAL n 2 49 ALA n 2 50 GLY n 2 51 ILE n 2 52 SER n 2 53 SER n 2 54 GLY n 2 55 GLY n 2 56 SER n 2 57 TYR n 2 58 THR n 2 59 PHE n 2 60 TYR n 2 61 PRO n 2 62 ASP n 2 63 THR n 2 64 VAL n 2 65 LYS n 2 66 GLY n 2 67 ARG n 2 68 PHE n 2 69 ILE n 2 70 ILE n 2 71 SER n 2 72 ARG n 2 73 ASN n 2 74 ASN n 2 75 ALA n 2 76 ARG n 2 77 ASN n 2 78 THR n 2 79 LEU n 2 80 SER n 2 81 LEU n 2 82 GLN n 2 83 MET n 2 84 SER n 2 85 SER n 2 86 LEU n 2 87 ARG n 2 88 SER n 2 89 GLU n 2 90 ASP n 2 91 THR n 2 92 ALA n 2 93 ILE n 2 94 TYR n 2 95 TYR n 2 96 CYS n 2 97 THR n 2 98 ARG n 2 99 TYR n 2 100 SER n 2 101 SER n 2 102 ASP n 2 103 PRO n 2 104 PHE n 2 105 TYR n 2 106 PHE n 2 107 ASP n 2 108 TYR n 2 109 TRP n 2 110 GLY n 2 111 GLN n 2 112 GLY n 2 113 THR n 2 114 THR n 2 115 LEU n 2 116 THR n 2 117 VAL n 2 118 SER n 2 119 SER n 2 120 ALA n 2 121 LYS n 2 122 THR n 2 123 THR n 2 124 PRO n 2 125 PRO n 2 126 SER n 2 127 VAL n 2 128 TYR n 2 129 PRO n 2 130 LEU n 2 131 ALA n 2 132 PRO n 2 133 GLY n 2 134 SER n 2 135 ALA n 2 136 ALA n 2 137 GLN n 2 138 THR n 2 139 ASN n 2 140 SER n 2 141 MET n 2 142 VAL n 2 143 THR n 2 144 LEU n 2 145 GLY n 2 146 CYS n 2 147 LEU n 2 148 VAL n 2 149 LYS n 2 150 GLY n 2 151 TYR n 2 152 PHE n 2 153 PRO n 2 154 GLU n 2 155 PRO n 2 156 VAL n 2 157 THR n 2 158 VAL n 2 159 THR n 2 160 TRP n 2 161 ASN n 2 162 SER n 2 163 GLY n 2 164 SER n 2 165 LEU n 2 166 SER n 2 167 SER n 2 168 GLY n 2 169 VAL n 2 170 HIS n 2 171 THR n 2 172 PHE n 2 173 PRO n 2 174 ALA n 2 175 VAL n 2 176 LEU n 2 177 GLN n 2 178 SER n 2 179 ASP n 2 180 LEU n 2 181 TYR n 2 182 THR n 2 183 LEU n 2 184 SER n 2 185 SER n 2 186 SER n 2 187 VAL n 2 188 THR n 2 189 VAL n 2 190 PRO n 2 191 SER n 2 192 SER n 2 193 PRO n 2 194 ARG n 2 195 PRO n 2 196 SER n 2 197 GLU n 2 198 THR n 2 199 VAL n 2 200 THR n 2 201 CYS n 2 202 ASN n 2 203 VAL n 2 204 ALA n 2 205 HIS n 2 206 PRO n 2 207 ALA n 2 208 SER n 2 209 SER n 2 210 THR n 2 211 LYS n 2 212 VAL n 2 213 ASP n 2 214 LYS n 2 215 LYS n 2 216 ILE n 2 217 VAL n 2 218 PRO n 2 219 ARG n 2 220 ASP n 2 221 CYS n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample ? ? ? 'house mouse' ? ? ? A/J ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 2 1 sample ? ? ? 'house mouse' ? ? ? A/J ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.entity_id _struct_ref.pdbx_db_accession _struct_ref.pdbx_align_begin _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_db_isoform 1 PIR PC4203 1 PC4203 1 ;DVLMTQTPLSLPVSLGDQASISCRSSQSIVHTNGNTYLEWYLQKPGQSPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKI SRVEAEDLGVYYCFQGSHVPRTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSER QNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC ; ? 2 PIR S38864 2 S38864 1 ;QVKLLESGGDLVKPGGSLKLSCAASGLTFSSYGMSWVRQIPDKRLEWVATISSGGTYTYYPDSVKGRFTISRDNAKNTLY LQMSSLKSEDTAMYYCARQGVSTMIRFAYWGQGTLVTVSAGKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVT WNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCIVPEVSSVFIFPP KPKDVLTRSTIQLYCFIYGHILNDVSVSWLMDDREITDTLAQTVLIKEEGKLASTCSKLNITEQQWMSESTFTCKVTSQG VDYLAHTRRCPDHEPRGVITYLIPPSPLDLYQNGAPKLTCLVVDLESEKNVNVTWNQEKKTSVSASQWYTKHHNNATTSI TSILPVVAKDWIEGYGYQCIVDHPDFPKPIVRSITKTPGQRSAPEVYVFPPPEEESEDKRTLTCLIQNFFPEDISVQWLG DGKLISNSQHSTTTPLKSNGSNRGFFIFSRLEVAKTLWTQRKQFTCQVIHEALQKPRKLEKTISTSTS ; ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 1IGF L 1 ? 219 ? PC4203 1 ? 219 ? 1 214 2 2 1IGF H 2 ? 221 ? S38864 2 ? 222 ? 2 230 3 1 1IGF M 1 ? 219 ? PC4203 1 ? 219 ? 1 214 4 2 1IGF J 2 ? 221 ? S38864 2 ? 222 ? 2 230 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 1IGF ASN L 26 ? PIR PC4203 SER 26 CONFLICT 26 1 1 1IGF THR L 28 A PIR PC4203 SER 28 CONFLICT 27 2 1 1IGF LEU L 30 C PIR PC4203 VAL 30 CONFLICT 27 3 1 1IGF LEU L 31 D PIR PC4203 HIS 31 CONFLICT 27 4 1 1IGF SER L 32 E PIR PC4203 THR 32 CONFLICT 27 5 1 1IGF ASP L 33 ? PIR PC4203 ASN 33 CONFLICT 28 6 1 1IGF ASP L 35 ? PIR PC4203 ASN 35 CONFLICT 30 7 1 1IGF PRO L 101 ? PIR PC4203 ARG 101 CONFLICT 96 8 2 1IGF GLN H 3 ? PIR S38864 LYS 3 CONFLICT 3 9 2 1IGF VAL H 5 ? PIR S38864 LEU 5 CONFLICT 5 10 2 1IGF PHE H 27 ? PIR S38864 LEU 27 CONFLICT 27 11 2 1IGF ARG H 31 ? PIR S38864 SER 31 CONFLICT 31 12 2 1IGF CYS H 32 ? PIR S38864 TYR 32 CONFLICT 32 13 2 1IGF ALA H 33 ? PIR S38864 GLY 33 CONFLICT 33 14 2 1IGF THR H 40 ? PIR S38864 ILE 40 CONFLICT 40 15 2 1IGF GLU H 42 ? PIR S38864 ASP 42 CONFLICT 42 16 2 1IGF GLY H 50 ? PIR S38864 THR 50 CONFLICT 50 17 2 1IGF SER H 56 ? PIR S38864 THR 56 CONFLICT 55 18 2 1IGF PHE H 59 ? PIR S38864 TYR 59 CONFLICT 58 19 2 1IGF THR H 63 ? PIR S38864 SER 63 CONFLICT 62 20 2 1IGF ILE H 69 ? PIR S38864 THR 69 CONFLICT 68 21 2 1IGF ASN H 73 ? PIR S38864 ASP 73 CONFLICT 72 22 2 1IGF ARG H 76 ? PIR S38864 LYS 76 CONFLICT 75 23 2 1IGF SER H 80 ? PIR S38864 TYR 80 CONFLICT 79 24 2 1IGF ARG H 87 ? PIR S38864 LYS 87 CONFLICT 83 25 2 1IGF ILE H 93 ? PIR S38864 MET 93 CONFLICT 89 26 2 1IGF THR H 97 ? PIR S38864 ALA 97 CONFLICT 93 27 2 1IGF ? H ? ? PIR S38864 GLN 99 DELETION ? 28 2 1IGF TYR H 99 ? PIR S38864 GLY 100 CONFLICT 95 29 2 1IGF SER H 100 ? PIR S38864 VAL 101 CONFLICT 96 30 2 1IGF ASP H 102 ? PIR S38864 THR 103 CONFLICT 98 31 2 1IGF PRO H 103 ? PIR S38864 MET 104 CONFLICT 99 32 2 1IGF PHE H 104 ? PIR S38864 ILE 105 CONFLICT 100 33 2 1IGF TYR H 105 B PIR S38864 ARG 106 CONFLICT 100 34 2 1IGF ASP H 107 ? PIR S38864 ALA 108 CONFLICT 101 35 2 1IGF THR H 114 ? PIR S38864 LEU 115 CONFLICT 108 36 2 1IGF LEU H 115 ? PIR S38864 VAL 116 CONFLICT 109 37 2 1IGF SER H 119 ? PIR S38864 ALA 120 CONFLICT 113 38 2 1IGF ALA H 120 ? PIR S38864 GLY 121 CONFLICT 114 39 2 1IGF PRO H 193 ? PIR S38864 THR 194 CONFLICT 198 40 2 1IGF ARG H 194 ? PIR S38864 TRP 195 CONFLICT 199 41 3 1IGF ASN M 26 ? PIR PC4203 SER 26 CONFLICT 26 42 3 1IGF THR M 28 A PIR PC4203 SER 28 CONFLICT 27 43 3 1IGF LEU M 30 C PIR PC4203 VAL 30 CONFLICT 27 44 3 1IGF LEU M 31 D PIR PC4203 HIS 31 CONFLICT 27 45 3 1IGF SER M 32 E PIR PC4203 THR 32 CONFLICT 27 46 3 1IGF ASP M 33 ? PIR PC4203 ASN 33 CONFLICT 28 47 3 1IGF ASP M 35 ? PIR PC4203 ASN 35 CONFLICT 30 48 3 1IGF PRO M 101 ? PIR PC4203 ARG 101 CONFLICT 96 49 4 1IGF GLN J 3 ? PIR S38864 LYS 3 CONFLICT 3 50 4 1IGF VAL J 5 ? PIR S38864 LEU 5 CONFLICT 5 51 4 1IGF PHE J 27 ? PIR S38864 LEU 27 CONFLICT 27 52 4 1IGF ARG J 31 ? PIR S38864 SER 31 CONFLICT 31 53 4 1IGF CYS J 32 ? PIR S38864 TYR 32 CONFLICT 32 54 4 1IGF ALA J 33 ? PIR S38864 GLY 33 CONFLICT 33 55 4 1IGF THR J 40 ? PIR S38864 ILE 40 CONFLICT 40 56 4 1IGF GLU J 42 ? PIR S38864 ASP 42 CONFLICT 42 57 4 1IGF GLY J 50 ? PIR S38864 THR 50 CONFLICT 50 58 4 1IGF SER J 56 ? PIR S38864 THR 56 CONFLICT 55 59 4 1IGF PHE J 59 ? PIR S38864 TYR 59 CONFLICT 58 60 4 1IGF THR J 63 ? PIR S38864 SER 63 CONFLICT 62 61 4 1IGF ILE J 69 ? PIR S38864 THR 69 CONFLICT 68 62 4 1IGF ASN J 73 ? PIR S38864 ASP 73 CONFLICT 72 63 4 1IGF ARG J 76 ? PIR S38864 LYS 76 CONFLICT 75 64 4 1IGF SER J 80 ? PIR S38864 TYR 80 CONFLICT 79 65 4 1IGF ARG J 87 ? PIR S38864 LYS 87 CONFLICT 83 66 4 1IGF ILE J 93 ? PIR S38864 MET 93 CONFLICT 89 67 4 1IGF THR J 97 ? PIR S38864 ALA 97 CONFLICT 93 68 4 1IGF ? J ? ? PIR S38864 GLN 99 DELETION ? 69 4 1IGF TYR J 99 ? PIR S38864 GLY 100 CONFLICT 95 70 4 1IGF SER J 100 ? PIR S38864 VAL 101 CONFLICT 96 71 4 1IGF ASP J 102 ? PIR S38864 THR 103 CONFLICT 98 72 4 1IGF PRO J 103 ? PIR S38864 MET 104 CONFLICT 99 73 4 1IGF PHE J 104 ? PIR S38864 ILE 105 CONFLICT 100 74 4 1IGF TYR J 105 B PIR S38864 ARG 106 CONFLICT 100 75 4 1IGF ASP J 107 ? PIR S38864 ALA 108 CONFLICT 101 76 4 1IGF THR J 114 ? PIR S38864 LEU 115 CONFLICT 108 77 4 1IGF LEU J 115 ? PIR S38864 VAL 116 CONFLICT 109 78 4 1IGF SER J 119 ? PIR S38864 ALA 120 CONFLICT 113 79 4 1IGF ALA J 120 ? PIR S38864 GLY 121 CONFLICT 114 80 4 1IGF PRO J 193 ? PIR S38864 THR 194 CONFLICT 198 81 4 1IGF ARG J 194 ? PIR S38864 TRP 195 CONFLICT 199 82 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 1IGF _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number ? # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 3.13 _exptl_crystal.density_percent_sol 60.69 _exptl_crystal.description ? # _diffrn.id 1 _diffrn.ambient_temp ? _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l ? _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol ? _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength . _diffrn_radiation_wavelength.wt 1.0 # _refine.entry_id 1IGF _refine.ls_number_reflns_obs ? _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 8.0 _refine.ls_d_res_high 2.8 _refine.ls_percent_reflns_obs ? _refine.ls_R_factor_obs ? _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.18 _refine.ls_R_factor_R_free ? _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free ? _refine.ls_number_reflns_R_free ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.B_iso_mean ? _refine.aniso_B[1][1] ? _refine.aniso_B[2][2] ? _refine.aniso_B[3][3] ? _refine.aniso_B[1][2] ? _refine.aniso_B[1][3] ? _refine.aniso_B[2][3] ? _refine.solvent_model_details ? _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_ls_cross_valid_method ? _refine.details ? _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct ? _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values ? _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details ? _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_overall_phase_error ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6686 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 14 _refine_hist.number_atoms_solvent 0 _refine_hist.number_atoms_total 6700 _refine_hist.d_res_high 2.8 _refine_hist.d_res_low 8.0 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function x_bond_d 0.015 ? ? ? 'X-RAY DIFFRACTION' ? x_bond_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_bond_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_deg 3.71 ? ? ? 'X-RAY DIFFRACTION' ? x_angle_deg_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_angle_deg_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_dihedral_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? x_dihedral_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_dihedral_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_improper_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? x_improper_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? x_improper_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? x_mcbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? x_mcangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? x_scbond_it ? ? ? ? 'X-RAY DIFFRACTION' ? x_scangle_it ? ? ? ? 'X-RAY DIFFRACTION' ? # _struct_ncs_oper.id 1 _struct_ncs_oper.code given _struct_ncs_oper.details ? _struct_ncs_oper.matrix[1][1] 0.246000 _struct_ncs_oper.matrix[1][2] 0.126140 _struct_ncs_oper.matrix[1][3] -0.961030 _struct_ncs_oper.matrix[2][1] -0.043090 _struct_ncs_oper.matrix[2][2] 0.991940 _struct_ncs_oper.matrix[2][3] 0.119160 _struct_ncs_oper.matrix[3][1] 0.968310 _struct_ncs_oper.matrix[3][2] 0.012090 _struct_ncs_oper.matrix[3][3] 0.249460 _struct_ncs_oper.vector[1] 5.20720 _struct_ncs_oper.vector[2] 16.41404 _struct_ncs_oper.vector[3] 4.87641 # _struct.entry_id 1IGF _struct.title 'CRYSTAL STRUCTURES OF AN ANTIBODY TO A PEPTIDE AND ITS COMPLEX WITH PEPTIDE ANTIGEN AT 2.8 ANGSTROMS' _struct.pdbx_descriptor ;IGG1 FAB' FRAGMENT (B13I2) ; _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 1IGF _struct_keywords.pdbx_keywords IMMUNOGLOBULIN _struct_keywords.text IMMUNOGLOBULIN # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 1 ? D N N 2 ? E N N 3 ? # _struct_biol.id 1 _struct_biol.details ;THE TWO FAB' HEAVY CHAINS (RESIDUES 1-227) OF THE ASYMMETRIC UNIT HAVE BEEN ASSIGNED CHAIN INDICATORS *H* AND *J*. THERE ARE TWO FAB MOLECULES PER ASYMMETRIC UNIT. THE NON-CRYSTALLOGRAPHIC TRANSFORMATION PRESENTED ON THE *MTRIX* RECORDS BELOW YIELDS APPROXIMATE COORDINATES FOR MOLECULE 2 WHEN APPLIED TO MOLECULE 1 (COORDINATES OF CHAIN *M* FROM CHAIN *L* AND COORDINATES OF CHAIN *J* FROM CHAIN *H*). ; _struct_biol.pdbx_parent_biol_id ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 GLU A 84 ? LEU A 88 ? GLU L 79 LEU L 83 5 ? 5 HELX_P HELX_P2 2 SER A 126 ? SER A 132 ? SER L 121 SER L 127 1 ? 7 HELX_P HELX_P3 3 LYS A 188 ? HIS A 194 ? LYS L 183 HIS L 189 1 ? 7 HELX_P HELX_P4 4 THR B 28 ? CYS B 32 ? THR H 28 CYS H 32 5 ? 5 HELX_P HELX_P5 5 ARG B 87 ? THR B 91 ? ARG H 83 THR H 87 5 ? 5 HELX_P HELX_P6 6 SER B 162 ? SER B 164 ? SER H 163 SER H 165 5 ? 3 HELX_P HELX_P7 7 SER B 192 ? GLU B 197 ? SER H 196 GLU H 203 1 ? 6 HELX_P HELX_P8 8 PRO B 206 ? SER B 209 ? PRO H 213 SER H 216 5 ? 4 HELX_P HELX_P9 9 GLU C 84 ? LEU C 88 ? GLU M 79 LEU M 83 5 ? 5 HELX_P HELX_P10 10 SER C 126 ? SER C 132 ? SER M 121 SER M 127 1 ? 7 HELX_P HELX_P11 11 LYS C 188 ? GLU C 192 ? LYS M 183 GLU M 187 1 ? 5 HELX_P HELX_P12 12 ARG D 87 ? THR D 91 ? ARG J 83 THR J 87 5 ? 5 HELX_P HELX_P13 13 SER D 162 ? SER D 164 ? SER J 163 SER J 165 5 ? 3 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 23 SG ? ? ? 1_555 A CYS 93 SG ? ? L CYS 23 L CYS 88 1_555 ? ? ? ? ? ? ? 2.011 ? disulf2 disulf ? ? A CYS 139 SG ? ? ? 1_555 A CYS 199 SG ? ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.011 ? disulf3 disulf ? ? B CYS 22 SG ? ? ? 1_555 B CYS 96 SG ? ? H CYS 22 H CYS 92 1_555 ? ? ? ? ? ? ? 1.991 ? disulf4 disulf ? ? B CYS 146 SG ? ? ? 1_555 B CYS 201 SG ? ? H CYS 142 H CYS 208 1_555 ? ? ? ? ? ? ? 2.007 ? disulf5 disulf ? ? C CYS 23 SG ? ? ? 1_555 C CYS 93 SG ? ? M CYS 23 M CYS 88 1_555 ? ? ? ? ? ? ? 2.022 ? disulf6 disulf ? ? C CYS 139 SG ? ? ? 1_555 C CYS 199 SG ? ? M CYS 134 M CYS 194 1_555 ? ? ? ? ? ? ? 2.021 ? disulf7 disulf ? ? D CYS 22 SG ? ? ? 1_555 D CYS 96 SG ? ? J CYS 22 J CYS 92 1_555 ? ? ? ? ? ? ? 2.032 ? disulf8 disulf ? ? D CYS 146 SG ? ? ? 1_555 D CYS 201 SG ? ? J CYS 142 J CYS 208 1_555 ? ? ? ? ? ? ? 2.014 ? covale1 covale ? ? A ASN 26 ND2 ? ? ? 1_555 E NAG . C1 ? ? L ASN 26 L NAG 901 1_555 ? ? ? ? ? ? ? 1.471 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 THR 7 A . ? THR 7 L PRO 8 A ? PRO 8 L 1 -5.08 2 VAL 99 A . ? VAL 94 L PRO 100 A ? PRO 95 L 1 -6.32 3 TYR 145 A . ? TYR 140 L PRO 146 A ? PRO 141 L 1 -11.09 4 PHE 152 B . ? PHE 148 H PRO 153 B ? PRO 149 H 1 -25.27 5 GLU 154 B . ? GLU 150 H PRO 155 B ? PRO 151 H 1 17.00 6 THR 7 C . ? THR 7 M PRO 8 C ? PRO 8 M 1 0.79 7 TYR 145 C . ? TYR 140 M PRO 146 C ? PRO 141 M 1 -12.62 8 PHE 152 D . ? PHE 148 J PRO 153 D ? PRO 149 J 1 -14.74 9 GLU 154 D . ? GLU 150 J PRO 155 D ? PRO 151 J 1 -6.84 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 4 ? B ? 5 ? C ? 6 ? D ? 4 ? E ? 4 ? F ? 4 ? G ? 5 ? H ? 6 ? I ? 4 ? J ? 4 ? K ? 3 ? L ? 4 ? M ? 5 ? N ? 6 ? O ? 4 ? P ? 3 ? Q ? 4 ? R ? 4 ? S ? 5 ? T ? 6 ? U ? 4 ? V ? 4 ? W ? 3 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel B 4 5 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel C 3 4 ? anti-parallel C 4 5 ? anti-parallel C 5 6 ? parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel G 1 2 ? anti-parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel H 5 6 ? parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel L 1 2 ? anti-parallel L 2 3 ? anti-parallel L 3 4 ? anti-parallel M 1 2 ? anti-parallel M 2 3 ? anti-parallel M 3 4 ? anti-parallel M 4 5 ? anti-parallel N 1 2 ? anti-parallel N 2 3 ? anti-parallel N 3 4 ? anti-parallel N 4 5 ? anti-parallel N 5 6 ? parallel O 1 2 ? anti-parallel O 2 3 ? anti-parallel O 3 4 ? anti-parallel P 1 2 ? anti-parallel P 2 3 ? anti-parallel Q 1 2 ? anti-parallel Q 2 3 ? anti-parallel Q 3 4 ? anti-parallel R 1 2 ? anti-parallel R 2 3 ? anti-parallel R 3 4 ? anti-parallel S 1 2 ? anti-parallel S 2 3 ? anti-parallel S 3 4 ? anti-parallel T 1 2 ? anti-parallel T 2 3 ? anti-parallel T 3 4 ? anti-parallel T 4 5 ? anti-parallel T 5 6 ? parallel U 1 2 ? anti-parallel U 2 3 ? anti-parallel U 3 4 ? anti-parallel V 1 2 ? anti-parallel V 2 3 ? anti-parallel V 3 4 ? anti-parallel W 1 2 ? anti-parallel W 2 3 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 MET A 4 ? THR A 7 ? MET L 4 THR L 7 A 2 ALA A 19 ? SER A 25 ? ALA L 19 SER L 25 A 3 ASP A 75 ? ILE A 80 ? ASP L 70 ILE L 75 A 4 PHE A 67 ? SER A 72 ? PHE L 62 SER L 67 B 1 ASN A 58 ? ARG A 59 ? ASN L 53 ARG L 54 B 2 LYS A 50 ? TYR A 54 ? LYS L 45 TYR L 49 B 3 LEU A 38 ? GLN A 43 ? LEU L 33 GLN L 38 B 4 GLY A 89 ? GLN A 95 ? GLY L 84 GLN L 90 B 5 THR A 102 ? PHE A 103 ? THR L 97 PHE L 98 C 1 ASN A 58 ? ARG A 59 ? ASN L 53 ARG L 54 C 2 LYS A 50 ? TYR A 54 ? LYS L 45 TYR L 49 C 3 LEU A 38 ? GLN A 43 ? LEU L 33 GLN L 38 C 4 GLY A 89 ? GLN A 95 ? GLY L 84 GLN L 90 C 5 THR A 107 ? ILE A 111 ? THR L 102 ILE L 106 C 6 SER A 10 ? VAL A 13 ? SER L 10 VAL L 13 D 1 THR A 119 ? PHE A 123 ? THR L 114 PHE L 118 D 2 GLY A 134 ? PHE A 144 ? GLY L 129 PHE L 139 D 3 TYR A 178 ? THR A 187 ? TYR L 173 THR L 182 D 4 VAL A 164 ? TRP A 168 ? VAL L 159 TRP L 163 E 1 GLU A 159 ? GLN A 161 ? GLU L 154 GLN L 156 E 2 ASN A 150 ? ILE A 155 ? ASN L 145 ILE L 150 E 3 SER A 196 ? THR A 202 ? SER L 191 THR L 197 E 4 ILE A 210 ? ASN A 215 ? ILE L 205 ASN L 210 F 1 GLN B 3 ? SER B 7 ? GLN H 3 SER H 7 F 2 LEU B 18 ? SER B 25 ? LEU H 18 SER H 25 F 3 THR B 78 ? MET B 83 ? THR H 77 MET H 82 F 4 PHE B 68 ? SER B 71 ? PHE H 67 SER H 70 G 1 THR B 58 ? PHE B 59 ? THR H 57 PHE H 58 G 2 LEU B 45 ? ILE B 51 ? LEU H 45 ILE H 51 G 3 MET B 34 ? GLN B 39 ? MET H 34 GLN H 39 G 4 ALA B 92 ? TYR B 99 ? ALA H 88 TYR H 95 H 1 THR B 58 ? PHE B 59 ? THR H 57 PHE H 58 H 2 LEU B 45 ? ILE B 51 ? LEU H 45 ILE H 51 H 3 MET B 34 ? GLN B 39 ? MET H 34 GLN H 39 H 4 ALA B 92 ? TYR B 99 ? ALA H 88 TYR H 95 H 5 THR B 113 ? VAL B 117 ? THR H 107 VAL H 111 H 6 LEU B 11 ? VAL B 12 ? LEU H 11 VAL H 12 I 1 SER B 126 ? LEU B 130 ? SER H 120 LEU H 124 I 2 MET B 141 ? TYR B 151 ? MET H 137 TYR H 147 I 3 TYR B 181 ? PRO B 190 ? TYR H 185 PRO H 194 I 4 GLY B 168 ? THR B 171 ? GLY H 169 THR H 173 J 1 SER B 126 ? LEU B 130 ? SER H 120 LEU H 124 J 2 MET B 141 ? TYR B 151 ? MET H 137 TYR H 147 J 3 TYR B 181 ? PRO B 190 ? TYR H 185 PRO H 194 J 4 VAL B 175 ? LEU B 176 ? VAL H 177 LEU H 178 K 1 THR B 157 ? TRP B 160 ? THR H 153 TRP H 157 K 2 VAL B 199 ? HIS B 205 ? VAL H 205 HIS H 212 K 3 THR B 210 ? ILE B 216 ? THR H 217 ILE H 223 L 1 THR C 5 ? THR C 7 ? THR M 5 THR M 7 L 2 ALA C 19 ? ARG C 24 ? ALA M 19 ARG M 24 L 3 ASP C 75 ? ILE C 80 ? ASP M 70 ILE M 75 L 4 PHE C 67 ? SER C 72 ? PHE M 62 SER M 67 M 1 ASN C 58 ? ARG C 59 ? ASN M 53 ARG M 54 M 2 LYS C 50 ? TYR C 54 ? LYS M 45 TYR M 49 M 3 LEU C 38 ? GLN C 43 ? LEU M 33 GLN M 38 M 4 GLY C 89 ? GLN C 95 ? GLY M 84 GLN M 90 M 5 THR C 102 ? PHE C 103 ? THR M 97 PHE M 98 N 1 ASN C 58 ? ARG C 59 ? ASN M 53 ARG M 54 N 2 LYS C 50 ? TYR C 54 ? LYS M 45 TYR M 49 N 3 LEU C 38 ? GLN C 43 ? LEU M 33 GLN M 38 N 4 GLY C 89 ? GLN C 95 ? GLY M 84 GLN M 90 N 5 THR C 107 ? ILE C 111 ? THR M 102 ILE M 106 N 6 SER C 10 ? VAL C 13 ? SER M 10 VAL M 13 O 1 THR C 119 ? PHE C 123 ? THR M 114 PHE M 118 O 2 GLY C 134 ? PHE C 144 ? GLY M 129 PHE M 139 O 3 TYR C 178 ? THR C 187 ? TYR M 173 THR M 182 O 4 VAL C 164 ? TRP C 168 ? VAL M 159 TRP M 163 P 1 ASN C 150 ? ILE C 155 ? ASN M 145 ILE M 150 P 2 SER C 196 ? THR C 202 ? SER M 191 THR M 197 P 3 ILE C 210 ? ASN C 215 ? ILE M 205 ASN M 210 Q 1 GLN D 3 ? SER D 7 ? GLN J 3 SER J 7 Q 2 LEU D 18 ? SER D 25 ? LEU J 18 SER J 25 Q 3 THR D 78 ? MET D 83 ? THR J 77 MET J 82 Q 4 PHE D 68 ? ILE D 69 ? PHE J 67 ILE J 68 R 1 GLN D 3 ? SER D 7 ? GLN J 3 SER J 7 R 2 LEU D 18 ? SER D 25 ? LEU J 18 SER J 25 R 3 THR D 78 ? MET D 83 ? THR J 77 MET J 82 R 4 ARG D 72 ? ASN D 73 ? ARG J 71 ASN J 72 S 1 THR D 58 ? PHE D 59 ? THR J 57 PHE J 58 S 2 LEU D 45 ? ILE D 51 ? LEU J 45 ILE J 51 S 3 MET D 34 ? GLN D 39 ? MET J 34 GLN J 39 S 4 ALA D 92 ? TYR D 99 ? ALA J 88 TYR J 95 T 1 THR D 58 ? PHE D 59 ? THR J 57 PHE J 58 T 2 LEU D 45 ? ILE D 51 ? LEU J 45 ILE J 51 T 3 MET D 34 ? GLN D 39 ? MET J 34 GLN J 39 T 4 ALA D 92 ? TYR D 99 ? ALA J 88 TYR J 95 T 5 THR D 113 ? VAL D 117 ? THR J 107 VAL J 111 T 6 LEU D 11 ? VAL D 12 ? LEU J 11 VAL J 12 U 1 SER D 126 ? LEU D 130 ? SER J 120 LEU J 124 U 2 MET D 141 ? TYR D 151 ? MET J 137 TYR J 147 U 3 TYR D 181 ? PRO D 190 ? TYR J 185 PRO J 194 U 4 HIS D 170 ? THR D 171 ? HIS J 172 THR J 173 V 1 SER D 126 ? LEU D 130 ? SER J 120 LEU J 124 V 2 MET D 141 ? TYR D 151 ? MET J 137 TYR J 147 V 3 TYR D 181 ? PRO D 190 ? TYR J 185 PRO J 194 V 4 VAL D 175 ? LEU D 176 ? VAL J 177 LEU J 178 W 1 THR D 157 ? TRP D 160 ? THR J 153 TRP J 157 W 2 VAL D 199 ? HIS D 205 ? VAL J 205 HIS J 212 W 3 THR D 210 ? ILE D 216 ? THR J 217 ILE J 223 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N THR A 7 ? N THR L 7 O SER A 22 ? O SER L 22 A 2 3 N CYS A 23 ? N CYS L 23 O PHE A 76 ? O PHE L 71 A 3 4 N LYS A 79 ? N LYS L 74 O SER A 68 ? O SER L 63 B 1 2 O ASN A 58 ? O ASN L 53 N TYR A 54 ? N TYR L 49 B 2 3 N LEU A 52 ? N LEU L 47 O TRP A 40 ? O TRP L 35 B 3 4 N GLN A 43 ? N GLN L 38 O VAL A 90 ? O VAL L 85 B 4 5 N GLN A 95 ? N GLN L 90 O THR A 102 ? O THR L 97 C 1 2 O ASN A 58 ? O ASN L 53 N TYR A 54 ? N TYR L 49 C 2 3 N LEU A 52 ? N LEU L 47 O TRP A 40 ? O TRP L 35 C 3 4 N GLN A 43 ? N GLN L 38 O VAL A 90 ? O VAL L 85 C 4 5 N TYR A 91 ? N TYR L 86 O THR A 107 ? O THR L 102 C 5 6 O LYS A 108 ? O LYS L 103 N LEU A 11 ? N LEU L 11 D 1 2 N PHE A 123 ? N PHE L 118 O VAL A 138 ? O VAL L 133 D 2 3 N PHE A 144 ? N PHE L 139 O TYR A 178 ? O TYR L 173 D 3 4 N THR A 183 ? N THR L 178 O LEU A 165 ? O LEU L 160 E 1 2 N GLN A 161 ? N GLN L 156 O TRP A 153 ? O TRP L 148 E 2 3 N LYS A 154 ? N LYS L 149 O THR A 198 ? O THR L 193 E 3 4 N ALA A 201 ? N ALA L 196 O ILE A 210 ? O ILE L 205 F 1 2 O SER B 7 ? O SER H 7 N SER B 21 ? N SER H 21 F 2 3 N CYS B 22 ? N CYS H 22 O LEU B 79 ? O LEU H 78 F 3 4 O GLN B 82 ? O GLN H 81 N ILE B 69 ? N ILE H 68 G 1 2 N PHE B 59 ? N PHE H 58 O GLY B 50 ? O GLY H 50 G 2 3 N ILE B 51 ? N ILE H 51 O MET B 34 ? O MET H 34 G 3 4 O GLN B 39 ? O GLN H 39 N ILE B 93 ? N ILE H 89 H 1 2 N PHE B 59 ? N PHE H 58 O GLY B 50 ? O GLY H 50 H 2 3 N ILE B 51 ? N ILE H 51 O MET B 34 ? O MET H 34 H 3 4 O GLN B 39 ? O GLN H 39 N ILE B 93 ? N ILE H 89 H 4 5 N TYR B 94 ? N TYR H 90 O THR B 113 ? O THR H 107 H 5 6 O THR B 116 ? O THR H 110 N VAL B 12 ? N VAL H 12 I 1 2 N LEU B 130 ? N LEU H 124 O GLY B 145 ? O GLY H 141 I 2 3 O TYR B 151 ? O TYR H 147 N TYR B 181 ? N TYR H 185 I 3 4 N THR B 188 ? N THR H 192 O GLY B 168 ? O GLY H 169 J 1 2 N LEU B 130 ? N LEU H 124 O GLY B 145 ? O GLY H 141 J 2 3 O TYR B 151 ? O TYR H 147 N TYR B 181 ? N TYR H 185 J 3 4 O THR B 182 ? O THR H 186 N VAL B 175 ? N VAL H 177 K 1 2 O THR B 159 ? O THR H 156 N ASN B 202 ? N ASN H 209 K 2 3 N HIS B 205 ? N HIS H 212 O THR B 210 ? O THR H 217 L 1 2 O THR C 7 ? O THR M 7 N SER C 22 ? N SER M 22 L 2 3 N CYS C 23 ? N CYS M 23 O PHE C 76 ? O PHE M 71 L 3 4 N LYS C 79 ? N LYS M 74 O SER C 68 ? O SER M 63 M 1 2 O ASN C 58 ? O ASN M 53 N TYR C 54 ? N TYR M 49 M 2 3 N LEU C 52 ? N LEU M 47 O TRP C 40 ? O TRP M 35 M 3 4 N GLN C 43 ? N GLN M 38 O VAL C 90 ? O VAL M 85 M 4 5 N GLN C 95 ? N GLN M 90 O THR C 102 ? O THR M 97 N 1 2 O ASN C 58 ? O ASN M 53 N TYR C 54 ? N TYR M 49 N 2 3 N LEU C 52 ? N LEU M 47 O TRP C 40 ? O TRP M 35 N 3 4 N GLN C 43 ? N GLN M 38 O VAL C 90 ? O VAL M 85 N 4 5 N TYR C 91 ? N TYR M 86 O THR C 107 ? O THR M 102 N 5 6 N GLU C 110 ? N GLU M 105 O LEU C 11 ? O LEU M 11 O 1 2 N PHE C 123 ? N PHE M 118 O VAL C 138 ? O VAL M 133 O 2 3 O PHE C 144 ? O PHE M 139 N TYR C 178 ? N TYR M 173 O 3 4 O THR C 183 ? O THR M 178 N LEU C 165 ? N LEU M 160 P 1 2 O LYS C 154 ? O LYS M 149 N THR C 198 ? N THR M 193 P 2 3 O ALA C 201 ? O ALA M 196 N ILE C 210 ? N ILE M 205 Q 1 2 N SER D 7 ? N SER J 7 O SER D 21 ? O SER J 21 Q 2 3 O CYS D 22 ? O CYS J 22 N LEU D 79 ? N LEU J 78 Q 3 4 N GLN D 82 ? N GLN J 81 O ILE D 69 ? O ILE J 68 R 1 2 N SER D 7 ? N SER J 7 O SER D 21 ? O SER J 21 R 2 3 O CYS D 22 ? O CYS J 22 N LEU D 79 ? N LEU J 78 R 3 4 O THR D 78 ? O THR J 77 N ASN D 73 ? N ASN J 72 S 1 2 N PHE D 59 ? N PHE J 58 O GLY D 50 ? O GLY J 50 S 2 3 N ILE D 51 ? N ILE J 51 O MET D 34 ? O MET J 34 S 3 4 O GLN D 39 ? O GLN J 39 N ILE D 93 ? N ILE J 89 T 1 2 N PHE D 59 ? N PHE J 58 O GLY D 50 ? O GLY J 50 T 2 3 N ILE D 51 ? N ILE J 51 O MET D 34 ? O MET J 34 T 3 4 O GLN D 39 ? O GLN J 39 N ILE D 93 ? N ILE J 89 T 4 5 N TYR D 94 ? N TYR J 90 O THR D 113 ? O THR J 107 T 5 6 O THR D 116 ? O THR J 110 N VAL D 12 ? N VAL J 12 U 1 2 N LEU D 130 ? N LEU J 124 O GLY D 145 ? O GLY J 141 U 2 3 O TYR D 151 ? O TYR J 147 N TYR D 181 ? N TYR J 185 U 3 4 N SER D 186 ? N SER J 190 O HIS D 170 ? O HIS J 172 V 1 2 N LEU D 130 ? N LEU J 124 O GLY D 145 ? O GLY J 141 V 2 3 O TYR D 151 ? O TYR J 147 N TYR D 181 ? N TYR J 185 V 3 4 O THR D 182 ? O THR J 186 N VAL D 175 ? N VAL J 177 W 1 2 O THR D 159 ? O THR J 156 N ASN D 202 ? N ASN J 209 W 2 3 O HIS D 205 ? O HIS J 212 N THR D 210 ? N THR J 217 # _struct_site.id AC1 _struct_site.pdbx_evidence_code Software _struct_site.pdbx_auth_asym_id ? _struct_site.pdbx_auth_comp_id ? _struct_site.pdbx_auth_seq_id ? _struct_site.pdbx_auth_ins_code ? _struct_site.pdbx_num_residues 4 _struct_site.details 'BINDING SITE FOR RESIDUE NAG L 901' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 4 ASP A 1 ? ASP L 1 . ? 1_555 ? 2 AC1 4 LEU A 3 ? LEU L 3 . ? 1_555 ? 3 AC1 4 ASN A 26 ? ASN L 26 . ? 1_555 ? 4 AC1 4 GLN A 27 ? GLN L 27 . ? 1_555 ? # _database_PDB_matrix.entry_id 1IGF _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 1IGF _atom_sites.fract_transf_matrix[1][1] 0.010204 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.006592 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.012376 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # _atom_sites_footnote.id 1 _atom_sites_footnote.text 'RESIDUES 8, 95, AND 141 OF THE *L* AND *M* CHAINS AND RESIDUES 149 AND 151 OF THE *H* AND *J* CHAINS ARE CIS PROLINES.' # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ASP A 1 1 ? -15.625 -0.305 41.305 1.00 23.99 ? 1 ASP L N 1 ATOM 2 C CA . ASP A 1 1 ? -14.604 0.292 42.151 1.00 29.35 ? 1 ASP L CA 1 ATOM 3 C C . ASP A 1 1 ? -15.496 1.385 42.674 1.00 23.54 ? 1 ASP L C 1 ATOM 4 O O . ASP A 1 1 ? -16.099 2.044 41.841 1.00 17.53 ? 1 ASP L O 1 ATOM 5 C CB . ASP A 1 1 ? -13.451 0.976 41.394 1.00 41.04 ? 1 ASP L CB 1 ATOM 6 C CG . ASP A 1 1 ? -12.898 0.311 40.132 1.00 50.73 ? 1 ASP L CG 1 ATOM 7 O OD1 . ASP A 1 1 ? -13.063 -0.898 39.932 1.00 53.08 ? 1 ASP L OD1 1 ATOM 8 O OD2 . ASP A 1 1 ? -12.297 1.033 39.332 1.00 57.26 ? 1 ASP L OD2 1 ATOM 9 N N . VAL A 1 2 ? -15.625 1.572 43.973 1.00 22.07 ? 2 VAL L N 1 ATOM 10 C CA . VAL A 1 2 ? -16.606 2.501 44.500 1.00 18.02 ? 2 VAL L CA 1 ATOM 11 C C . VAL A 1 2 ? -16.296 3.915 44.027 1.00 13.27 ? 2 VAL L C 1 ATOM 12 O O . VAL A 1 2 ? -15.145 4.341 44.102 1.00 15.12 ? 2 VAL L O 1 ATOM 13 C CB . VAL A 1 2 ? -16.595 2.403 46.036 1.00 20.78 ? 2 VAL L CB 1 ATOM 14 C CG1 . VAL A 1 2 ? -17.959 2.891 46.488 1.00 26.23 ? 2 VAL L CG1 1 ATOM 15 C CG2 . VAL A 1 2 ? -16.388 0.984 46.575 1.00 23.05 ? 2 VAL L CG2 1 ATOM 16 N N . LEU A 1 3 ? -17.258 4.565 43.396 1.00 5.91 ? 3 LEU L N 1 ATOM 17 C CA . LEU A 1 3 ? -17.106 5.925 42.941 1.00 10.90 ? 3 LEU L CA 1 ATOM 18 C C . LEU A 1 3 ? -17.405 6.748 44.163 1.00 21.50 ? 3 LEU L C 1 ATOM 19 O O . LEU A 1 3 ? -18.335 6.430 44.917 1.00 22.46 ? 3 LEU L O 1 ATOM 20 C CB . LEU A 1 3 ? -18.088 6.167 41.824 1.00 12.23 ? 3 LEU L CB 1 ATOM 21 C CG . LEU A 1 3 ? -18.591 7.470 41.229 1.00 11.98 ? 3 LEU L CG 1 ATOM 22 C CD1 . LEU A 1 3 ? -19.683 8.003 42.155 1.00 15.89 ? 3 LEU L CD1 1 ATOM 23 C CD2 . LEU A 1 3 ? -17.438 8.425 40.963 1.00 13.88 ? 3 LEU L CD2 1 ATOM 24 N N . MET A 1 4 ? -16.595 7.796 44.370 1.00 24.98 ? 4 MET L N 1 ATOM 25 C CA . MET A 1 4 ? -16.744 8.645 45.538 1.00 22.35 ? 4 MET L CA 1 ATOM 26 C C . MET A 1 4 ? -16.843 10.077 45.056 1.00 28.74 ? 4 MET L C 1 ATOM 27 O O . MET A 1 4 ? -15.844 10.683 44.631 1.00 30.19 ? 4 MET L O 1 ATOM 28 C CB . MET A 1 4 ? -15.560 8.509 46.439 1.00 13.48 ? 4 MET L CB 1 ATOM 29 C CG . MET A 1 4 ? -15.331 7.096 46.871 1.00 12.05 ? 4 MET L CG 1 ATOM 30 S SD . MET A 1 4 ? -16.172 6.927 48.444 1.00 25.25 ? 4 MET L SD 1 ATOM 31 C CE . MET A 1 4 ? -14.758 7.301 49.421 1.00 20.31 ? 4 MET L CE 1 ATOM 32 N N . THR A 1 5 ? -18.080 10.598 45.019 1.00 35.68 ? 5 THR L N 1 ATOM 33 C CA . THR A 1 5 ? -18.341 11.969 44.621 1.00 35.35 ? 5 THR L CA 1 ATOM 34 C C . THR A 1 5 ? -18.225 12.880 45.810 1.00 34.40 ? 5 THR L C 1 ATOM 35 O O . THR A 1 5 ? -18.873 12.690 46.848 1.00 34.54 ? 5 THR L O 1 ATOM 36 C CB . THR A 1 5 ? -19.714 12.186 44.094 1.00 36.23 ? 5 THR L CB 1 ATOM 37 O OG1 . THR A 1 5 ? -20.106 11.008 43.410 1.00 44.72 ? 5 THR L OG1 1 ATOM 38 C CG2 . THR A 1 5 ? -19.724 13.412 43.186 1.00 41.34 ? 5 THR L CG2 1 ATOM 39 N N . GLN A 1 6 ? -17.392 13.887 45.587 1.00 32.53 ? 6 GLN L N 1 ATOM 40 C CA . GLN A 1 6 ? -17.133 14.877 46.602 1.00 30.33 ? 6 GLN L CA 1 ATOM 41 C C . GLN A 1 6 ? -17.732 16.161 46.086 1.00 28.48 ? 6 GLN L C 1 ATOM 42 O O . GLN A 1 6 ? -17.809 16.330 44.857 1.00 30.77 ? 6 GLN L O 1 ATOM 43 C CB . GLN A 1 6 ? -15.652 15.051 46.780 1.00 27.32 ? 6 GLN L CB 1 ATOM 44 C CG . GLN A 1 6 ? -15.280 14.977 48.235 1.00 20.50 ? 6 GLN L CG 1 ATOM 45 C CD . GLN A 1 6 ? -13.808 15.226 48.398 1.00 17.65 ? 6 GLN L CD 1 ATOM 46 O OE1 . GLN A 1 6 ? -12.923 14.477 47.964 1.00 18.93 ? 6 GLN L OE1 1 ATOM 47 N NE2 . GLN A 1 6 ? -13.516 16.333 49.022 1.00 12.12 ? 6 GLN L NE2 1 ATOM 48 N N . THR A 1 7 ? -18.247 16.971 47.000 1.00 23.87 ? 7 THR L N 1 ATOM 49 C CA . THR A 1 7 ? -18.651 18.319 46.667 1.00 24.65 ? 7 THR L CA 1 ATOM 50 C C . THR A 1 7 ? -18.651 19.115 47.939 1.00 21.36 ? 7 THR L C 1 ATOM 51 O O . THR A 1 7 ? -18.933 18.568 49.011 1.00 21.59 ? 7 THR L O 1 ATOM 52 C CB . THR A 1 7 ? -20.086 18.518 46.058 1.00 29.39 ? 7 THR L CB 1 ATOM 53 O OG1 . THR A 1 7 ? -20.954 17.583 46.659 1.00 27.58 ? 7 THR L OG1 1 ATOM 54 C CG2 . THR A 1 7 ? -20.048 18.475 44.516 1.00 32.24 ? 7 THR L CG2 1 ATOM 55 N N . PRO A 1 8 ? -18.356 20.400 47.865 1.00 21.07 ? 8 PRO L N 1 ATOM 56 C CA . PRO A 1 8 ? -17.928 21.102 46.675 1.00 26.50 ? 8 PRO L CA 1 ATOM 57 C C . PRO A 1 8 ? -16.494 20.993 46.171 1.00 30.53 ? 8 PRO L C 1 ATOM 58 O O . PRO A 1 8 ? -15.536 20.492 46.752 1.00 25.84 ? 8 PRO L O 1 ATOM 59 C CB . PRO A 1 8 ? -18.329 22.514 46.977 1.00 28.36 ? 8 PRO L CB 1 ATOM 60 C CG . PRO A 1 8 ? -18.006 22.641 48.425 1.00 27.46 ? 8 PRO L CG 1 ATOM 61 C CD . PRO A 1 8 ? -18.688 21.359 48.904 1.00 27.76 ? 8 PRO L CD 1 ATOM 62 N N . LEU A 1 9 ? -16.448 21.443 44.940 1.00 32.40 ? 9 LEU L N 1 ATOM 63 C CA . LEU A 1 9 ? -15.215 21.586 44.220 1.00 37.17 ? 9 LEU L CA 1 ATOM 64 C C . LEU A 1 9 ? -14.322 22.513 45.036 1.00 34.75 ? 9 LEU L C 1 ATOM 65 O O . LEU A 1 9 ? -13.160 22.207 45.297 1.00 37.37 ? 9 LEU L O 1 ATOM 66 C CB . LEU A 1 9 ? -15.597 22.121 42.820 1.00 50.18 ? 9 LEU L CB 1 ATOM 67 C CG . LEU A 1 9 ? -16.625 23.281 42.362 1.00 59.91 ? 9 LEU L CG 1 ATOM 68 C CD1 . LEU A 1 9 ? -18.069 22.974 42.838 1.00 58.40 ? 9 LEU L CD1 1 ATOM 69 C CD2 . LEU A 1 9 ? -16.144 24.660 42.859 1.00 58.95 ? 9 LEU L CD2 1 ATOM 70 N N . SER A 1 10 ? -14.890 23.599 45.546 1.00 28.91 ? 10 SER L N 1 ATOM 71 C CA . SER A 1 10 ? -14.125 24.534 46.330 1.00 31.71 ? 10 SER L CA 1 ATOM 72 C C . SER A 1 10 ? -15.052 25.166 47.317 1.00 32.23 ? 10 SER L C 1 ATOM 73 O O . SER A 1 10 ? -16.166 25.563 46.980 1.00 40.41 ? 10 SER L O 1 ATOM 74 C CB . SER A 1 10 ? -13.543 25.625 45.487 1.00 32.99 ? 10 SER L CB 1 ATOM 75 O OG . SER A 1 10 ? -12.632 25.033 44.593 1.00 41.11 ? 10 SER L OG 1 ATOM 76 N N . LEU A 1 11 ? -14.613 25.308 48.538 1.00 27.49 ? 11 LEU L N 1 ATOM 77 C CA . LEU A 1 11 ? -15.482 25.841 49.548 1.00 27.60 ? 11 LEU L CA 1 ATOM 78 C C . LEU A 1 11 ? -14.812 27.111 50.008 1.00 26.19 ? 11 LEU L C 1 ATOM 79 O O . LEU A 1 11 ? -13.706 27.074 50.543 1.00 25.20 ? 11 LEU L O 1 ATOM 80 C CB . LEU A 1 11 ? -15.563 24.787 50.592 1.00 26.90 ? 11 LEU L CB 1 ATOM 81 C CG . LEU A 1 11 ? -16.621 24.794 51.620 1.00 24.61 ? 11 LEU L CG 1 ATOM 82 C CD1 . LEU A 1 11 ? -16.507 23.436 52.233 1.00 27.56 ? 11 LEU L CD1 1 ATOM 83 C CD2 . LEU A 1 11 ? -16.476 25.888 52.655 1.00 27.34 ? 11 LEU L CD2 1 ATOM 84 N N . PRO A 1 12 ? -15.391 28.266 49.753 1.00 29.86 ? 12 PRO L N 1 ATOM 85 C CA . PRO A 1 12 ? -14.758 29.542 50.071 1.00 29.58 ? 12 PRO L CA 1 ATOM 86 C C . PRO A 1 12 ? -15.184 29.949 51.464 1.00 26.40 ? 12 PRO L C 1 ATOM 87 O O . PRO A 1 12 ? -16.249 30.529 51.618 1.00 33.46 ? 12 PRO L O 1 ATOM 88 C CB . PRO A 1 12 ? -15.241 30.445 48.949 1.00 29.75 ? 12 PRO L CB 1 ATOM 89 C CG . PRO A 1 12 ? -15.707 29.470 47.886 1.00 32.70 ? 12 PRO L CG 1 ATOM 90 C CD . PRO A 1 12 ? -16.434 28.455 48.761 1.00 32.53 ? 12 PRO L CD 1 ATOM 91 N N . VAL A 1 13 ? -14.440 29.681 52.513 1.00 24.95 ? 13 VAL L N 1 ATOM 92 C CA . VAL A 1 13 ? -14.933 29.941 53.850 1.00 20.86 ? 13 VAL L CA 1 ATOM 93 C C . VAL A 1 13 ? -14.186 31.147 54.375 1.00 18.98 ? 13 VAL L C 1 ATOM 94 O O . VAL A 1 13 ? -13.106 31.461 53.869 1.00 18.37 ? 13 VAL L O 1 ATOM 95 C CB . VAL A 1 13 ? -14.674 28.658 54.647 1.00 21.62 ? 13 VAL L CB 1 ATOM 96 C CG1 . VAL A 1 13 ? -13.171 28.472 54.868 1.00 26.42 ? 13 VAL L CG1 1 ATOM 97 C CG2 . VAL A 1 13 ? -15.370 28.725 55.973 1.00 23.54 ? 13 VAL L CG2 1 ATOM 98 N N . SER A 1 14 ? -14.695 31.892 55.338 1.00 21.21 ? 14 SER L N 1 ATOM 99 C CA . SER A 1 14 ? -13.861 32.934 55.939 1.00 27.40 ? 14 SER L CA 1 ATOM 100 C C . SER A 1 14 ? -13.306 32.338 57.214 1.00 27.02 ? 14 SER L C 1 ATOM 101 O O . SER A 1 14 ? -13.826 31.332 57.724 1.00 32.44 ? 14 SER L O 1 ATOM 102 C CB . SER A 1 14 ? -14.632 34.213 56.323 1.00 29.10 ? 14 SER L CB 1 ATOM 103 O OG . SER A 1 14 ? -15.014 35.040 55.227 1.00 31.28 ? 14 SER L OG 1 ATOM 104 N N . LEU A 1 15 ? -12.236 32.944 57.720 1.00 23.88 ? 15 LEU L N 1 ATOM 105 C CA . LEU A 1 15 ? -11.651 32.510 58.958 1.00 19.56 ? 15 LEU L CA 1 ATOM 106 C C . LEU A 1 15 ? -12.702 32.696 60.036 1.00 28.80 ? 15 LEU L C 1 ATOM 107 O O . LEU A 1 15 ? -13.410 33.707 59.982 1.00 39.77 ? 15 LEU L O 1 ATOM 108 C CB . LEU A 1 15 ? -10.455 33.352 59.260 1.00 18.71 ? 15 LEU L CB 1 ATOM 109 C CG . LEU A 1 15 ? -9.259 33.185 58.361 1.00 21.86 ? 15 LEU L CG 1 ATOM 110 C CD1 . LEU A 1 15 ? -8.013 33.751 59.012 1.00 22.33 ? 15 LEU L CD1 1 ATOM 111 C CD2 . LEU A 1 15 ? -9.020 31.707 58.143 1.00 24.69 ? 15 LEU L CD2 1 ATOM 112 N N . GLY A 1 16 ? -12.896 31.741 60.952 1.00 27.98 ? 16 GLY L N 1 ATOM 113 C CA . GLY A 1 16 ? -13.882 31.885 61.990 1.00 20.60 ? 16 GLY L CA 1 ATOM 114 C C . GLY A 1 16 ? -15.121 31.145 61.609 1.00 16.68 ? 16 GLY L C 1 ATOM 115 O O . GLY A 1 16 ? -15.877 30.789 62.486 1.00 20.71 ? 16 GLY L O 1 ATOM 116 N N . ASP A 1 17 ? -15.425 30.887 60.362 1.00 20.56 ? 17 ASP L N 1 ATOM 117 C CA . ASP A 1 17 ? -16.605 30.106 60.112 1.00 26.39 ? 17 ASP L CA 1 ATOM 118 C C . ASP A 1 17 ? -16.297 28.642 60.128 1.00 26.70 ? 17 ASP L C 1 ATOM 119 O O . ASP A 1 17 ? -15.130 28.237 60.161 1.00 24.51 ? 17 ASP L O 1 ATOM 120 C CB . ASP A 1 17 ? -17.190 30.492 58.793 1.00 36.97 ? 17 ASP L CB 1 ATOM 121 C CG . ASP A 1 17 ? -17.879 31.846 58.844 1.00 48.34 ? 17 ASP L CG 1 ATOM 122 O OD1 . ASP A 1 17 ? -18.166 32.341 59.946 1.00 53.62 ? 17 ASP L OD1 1 ATOM 123 O OD2 . ASP A 1 17 ? -18.132 32.399 57.767 1.00 50.70 ? 17 ASP L OD2 1 ATOM 124 N N . GLN A 1 18 ? -17.433 27.956 60.116 1.00 23.45 ? 18 GLN L N 1 ATOM 125 C CA . GLN A 1 18 ? -17.564 26.518 60.104 1.00 26.44 ? 18 GLN L CA 1 ATOM 126 C C . GLN A 1 18 ? -17.648 26.155 58.657 1.00 24.22 ? 18 GLN L C 1 ATOM 127 O O . GLN A 1 18 ? -18.185 26.952 57.885 1.00 23.66 ? 18 GLN L O 1 ATOM 128 C CB . GLN A 1 18 ? -18.834 26.042 60.814 1.00 37.57 ? 18 GLN L CB 1 ATOM 129 C CG . GLN A 1 18 ? -20.070 26.978 60.858 1.00 58.26 ? 18 GLN L CG 1 ATOM 130 C CD . GLN A 1 18 ? -19.984 28.255 61.728 1.00 66.91 ? 18 GLN L CD 1 ATOM 131 O OE1 . GLN A 1 18 ? -19.640 28.229 62.910 1.00 67.68 ? 18 GLN L OE1 1 ATOM 132 N NE2 . GLN A 1 18 ? -20.314 29.440 61.197 1.00 69.68 ? 18 GLN L NE2 1 ATOM 133 N N . ALA A 1 19 ? -17.141 24.996 58.264 1.00 25.33 ? 19 ALA L N 1 ATOM 134 C CA . ALA A 1 19 ? -17.115 24.590 56.862 1.00 31.15 ? 19 ALA L CA 1 ATOM 135 C C . ALA A 1 19 ? -17.471 23.113 56.729 1.00 29.43 ? 19 ALA L C 1 ATOM 136 O O . ALA A 1 19 ? -17.046 22.315 57.572 1.00 30.85 ? 19 ALA L O 1 ATOM 137 C CB . ALA A 1 19 ? -15.707 24.804 56.243 1.00 25.31 ? 19 ALA L CB 1 ATOM 138 N N . SER A 1 20 ? -18.219 22.693 55.714 1.00 22.70 ? 20 SER L N 1 ATOM 139 C CA . SER A 1 20 ? -18.518 21.290 55.650 1.00 21.07 ? 20 SER L CA 1 ATOM 140 C C . SER A 1 20 ? -18.336 20.954 54.214 1.00 24.11 ? 20 SER L C 1 ATOM 141 O O . SER A 1 20 ? -18.672 21.726 53.306 1.00 15.22 ? 20 SER L O 1 ATOM 142 C CB . SER A 1 20 ? -19.929 21.001 56.034 1.00 24.81 ? 20 SER L CB 1 ATOM 143 O OG . SER A 1 20 ? -20.296 21.919 57.053 1.00 35.43 ? 20 SER L OG 1 ATOM 144 N N . ILE A 1 21 ? -17.679 19.811 54.148 1.00 28.18 ? 21 ILE L N 1 ATOM 145 C CA . ILE A 1 21 ? -17.319 19.130 52.926 1.00 28.76 ? 21 ILE L CA 1 ATOM 146 C C . ILE A 1 21 ? -18.099 17.827 53.020 1.00 28.85 ? 21 ILE L C 1 ATOM 147 O O . ILE A 1 21 ? -18.146 17.196 54.086 1.00 28.52 ? 21 ILE L O 1 ATOM 148 C CB . ILE A 1 21 ? -15.792 18.882 52.920 1.00 27.82 ? 21 ILE L CB 1 ATOM 149 C CG1 . ILE A 1 21 ? -15.072 20.223 52.903 1.00 25.35 ? 21 ILE L CG1 1 ATOM 150 C CG2 . ILE A 1 21 ? -15.401 17.998 51.732 1.00 26.36 ? 21 ILE L CG2 1 ATOM 151 C CD1 . ILE A 1 21 ? -13.582 20.110 53.260 1.00 29.19 ? 21 ILE L CD1 1 ATOM 152 N N . SER A 1 22 ? -18.705 17.432 51.921 1.00 28.56 ? 22 SER L N 1 ATOM 153 C CA . SER A 1 22 ? -19.462 16.204 51.862 1.00 31.62 ? 22 SER L CA 1 ATOM 154 C C . SER A 1 22 ? -18.898 15.283 50.799 1.00 31.01 ? 22 SER L C 1 ATOM 155 O O . SER A 1 22 ? -18.370 15.732 49.762 1.00 35.20 ? 22 SER L O 1 ATOM 156 C CB . SER A 1 22 ? -20.885 16.580 51.584 1.00 33.15 ? 22 SER L CB 1 ATOM 157 O OG . SER A 1 22 ? -20.914 17.762 50.779 1.00 45.60 ? 22 SER L OG 1 ATOM 158 N N . CYS A 1 23 ? -19.043 13.987 51.041 1.00 25.53 ? 23 CYS L N 1 ATOM 159 C CA . CYS A 1 23 ? -18.438 12.956 50.222 1.00 22.07 ? 23 CYS L CA 1 ATOM 160 C C . CYS A 1 23 ? -19.436 11.849 50.169 1.00 21.11 ? 23 CYS L C 1 ATOM 161 O O . CYS A 1 23 ? -19.976 11.463 51.214 1.00 19.65 ? 23 CYS L O 1 ATOM 162 C CB . CYS A 1 23 ? -17.170 12.509 50.907 1.00 25.99 ? 23 CYS L CB 1 ATOM 163 S SG . CYS A 1 23 ? -16.302 11.021 50.366 1.00 25.72 ? 23 CYS L SG 1 ATOM 164 N N . ARG A 1 24 ? -19.658 11.318 48.987 1.00 23.98 ? 24 ARG L N 1 ATOM 165 C CA . ARG A 1 24 ? -20.656 10.290 48.828 1.00 37.24 ? 24 ARG L CA 1 ATOM 166 C C . ARG A 1 24 ? -20.092 9.121 48.032 1.00 39.28 ? 24 ARG L C 1 ATOM 167 O O . ARG A 1 24 ? -19.421 9.299 47.017 1.00 41.96 ? 24 ARG L O 1 ATOM 168 C CB . ARG A 1 24 ? -21.875 10.865 48.109 1.00 44.13 ? 24 ARG L CB 1 ATOM 169 C CG . ARG A 1 24 ? -22.824 11.781 48.903 1.00 50.96 ? 24 ARG L CG 1 ATOM 170 C CD . ARG A 1 24 ? -23.327 12.902 47.964 1.00 58.60 ? 24 ARG L CD 1 ATOM 171 N NE . ARG A 1 24 ? -22.192 13.749 47.595 1.00 59.20 ? 24 ARG L NE 1 ATOM 172 C CZ . ARG A 1 24 ? -21.870 14.826 48.304 1.00 54.95 ? 24 ARG L CZ 1 ATOM 173 N NH1 . ARG A 1 24 ? -22.696 15.276 49.243 1.00 60.11 ? 24 ARG L NH1 1 ATOM 174 N NH2 . ARG A 1 24 ? -20.746 15.477 48.035 1.00 47.28 ? 24 ARG L NH2 1 ATOM 175 N N . SER A 1 25 ? -20.362 7.909 48.484 1.00 36.56 ? 25 SER L N 1 ATOM 176 C CA . SER A 1 25 ? -19.888 6.690 47.850 1.00 35.58 ? 25 SER L CA 1 ATOM 177 C C . SER A 1 25 ? -20.963 6.128 46.947 1.00 40.44 ? 25 SER L C 1 ATOM 178 O O . SER A 1 25 ? -22.084 6.083 47.451 1.00 47.61 ? 25 SER L O 1 ATOM 179 C CB . SER A 1 25 ? -19.601 5.737 48.924 1.00 31.71 ? 25 SER L CB 1 ATOM 180 O OG . SER A 1 25 ? -20.657 5.829 49.880 1.00 32.50 ? 25 SER L OG 1 ATOM 181 N N . ASN A 1 26 ? -20.813 5.651 45.703 1.00 39.34 ? 26 ASN L N 1 ATOM 182 C CA . ASN A 1 26 ? -21.974 5.166 44.953 1.00 35.50 ? 26 ASN L CA 1 ATOM 183 C C . ASN A 1 26 ? -22.337 3.734 45.319 1.00 36.43 ? 26 ASN L C 1 ATOM 184 O O . ASN A 1 26 ? -23.156 3.124 44.641 1.00 41.86 ? 26 ASN L O 1 ATOM 185 C CB . ASN A 1 26 ? -21.753 5.206 43.442 1.00 34.28 ? 26 ASN L CB 1 ATOM 186 C CG . ASN A 1 26 ? -20.756 4.171 42.954 1.00 39.23 ? 26 ASN L CG 1 ATOM 187 O OD1 . ASN A 1 26 ? -19.856 3.775 43.698 1.00 41.91 ? 26 ASN L OD1 1 ATOM 188 N ND2 . ASN A 1 26 ? -20.884 3.762 41.684 1.00 41.93 ? 26 ASN L ND2 1 ATOM 189 N N . GLN A 1 27 ? -21.746 3.168 46.361 1.00 38.62 ? 27 GLN L N 1 ATOM 190 C CA . GLN A 1 27 ? -21.975 1.817 46.874 1.00 39.17 ? 27 GLN L CA 1 ATOM 191 C C . GLN A 1 27 ? -21.641 1.983 48.354 1.00 40.08 ? 27 GLN L C 1 ATOM 192 O O . GLN A 1 27 ? -20.968 2.951 48.698 1.00 49.48 ? 27 GLN L O 1 ATOM 193 C CB . GLN A 1 27 ? -21.010 0.833 46.239 1.00 38.43 ? 27 GLN L CB 1 ATOM 194 C CG . GLN A 1 27 ? -21.286 -0.648 46.441 1.00 38.40 ? 27 GLN L CG 1 ATOM 195 C CD . GLN A 1 27 ? -20.046 -1.532 46.328 1.00 41.56 ? 27 GLN L CD 1 ATOM 196 O OE1 . GLN A 1 27 ? -19.321 -1.651 45.330 1.00 38.71 ? 27 GLN L OE1 1 ATOM 197 N NE2 . GLN A 1 27 ? -19.772 -2.196 47.443 1.00 37.77 ? 27 GLN L NE2 1 ATOM 198 N N . THR A 1 28 A -21.942 1.118 49.298 1.00 37.24 ? 27 THR L N 1 ATOM 199 C CA . THR A 1 28 A -21.714 1.509 50.682 1.00 42.30 ? 27 THR L CA 1 ATOM 200 C C . THR A 1 28 A -20.359 1.091 51.186 1.00 39.16 ? 27 THR L C 1 ATOM 201 O O . THR A 1 28 A -19.796 0.066 50.806 1.00 41.97 ? 27 THR L O 1 ATOM 202 C CB . THR A 1 28 A -22.878 0.955 51.610 1.00 52.14 ? 27 THR L CB 1 ATOM 203 O OG1 . THR A 1 28 A -22.323 0.499 52.852 1.00 57.22 ? 27 THR L OG1 1 ATOM 204 C CG2 . THR A 1 28 A -23.662 -0.174 50.949 1.00 57.15 ? 27 THR L CG2 1 ATOM 205 N N . ILE A 1 29 B -19.909 1.900 52.127 1.00 40.56 ? 27 ILE L N 1 ATOM 206 C CA . ILE A 1 29 B -18.620 1.783 52.785 1.00 39.77 ? 27 ILE L CA 1 ATOM 207 C C . ILE A 1 29 B -18.751 1.119 54.155 1.00 39.79 ? 27 ILE L C 1 ATOM 208 O O . ILE A 1 29 B -17.759 0.914 54.865 1.00 33.68 ? 27 ILE L O 1 ATOM 209 C CB . ILE A 1 29 B -18.045 3.236 52.813 1.00 38.32 ? 27 ILE L CB 1 ATOM 210 C CG1 . ILE A 1 29 B -17.993 3.724 51.383 1.00 39.66 ? 27 ILE L CG1 1 ATOM 211 C CG2 . ILE A 1 29 B -16.630 3.330 53.321 1.00 40.41 ? 27 ILE L CG2 1 ATOM 212 C CD1 . ILE A 1 29 B -17.446 2.710 50.319 1.00 42.18 ? 27 ILE L CD1 1 ATOM 213 N N . LEU A 1 30 C -19.978 0.802 54.588 1.00 44.26 ? 27 LEU L N 1 ATOM 214 C CA . LEU A 1 30 C -20.208 0.036 55.811 1.00 50.88 ? 27 LEU L CA 1 ATOM 215 C C . LEU A 1 30 C -19.832 -1.399 55.564 1.00 52.74 ? 27 LEU L C 1 ATOM 216 O O . LEU A 1 30 C -20.306 -2.118 54.682 1.00 50.59 ? 27 LEU L O 1 ATOM 217 C CB . LEU A 1 30 C -21.666 0.083 56.261 1.00 52.57 ? 27 LEU L CB 1 ATOM 218 C CG . LEU A 1 30 C -22.282 -0.858 57.301 1.00 52.33 ? 27 LEU L CG 1 ATOM 219 C CD1 . LEU A 1 30 C -21.433 -1.161 58.543 1.00 49.09 ? 27 LEU L CD1 1 ATOM 220 C CD2 . LEU A 1 30 C -23.552 -0.130 57.684 1.00 55.01 ? 27 LEU L CD2 1 ATOM 221 N N . LEU A 1 31 D -18.929 -1.790 56.417 1.00 56.87 ? 27 LEU L N 1 ATOM 222 C CA . LEU A 1 31 D -18.412 -3.107 56.270 1.00 60.00 ? 27 LEU L CA 1 ATOM 223 C C . LEU A 1 31 D -19.134 -3.848 57.365 1.00 65.89 ? 27 LEU L C 1 ATOM 224 O O . LEU A 1 31 D -19.185 -3.377 58.507 1.00 72.75 ? 27 LEU L O 1 ATOM 225 C CB . LEU A 1 31 D -16.934 -2.998 56.467 1.00 53.99 ? 27 LEU L CB 1 ATOM 226 C CG . LEU A 1 31 D -16.065 -4.030 55.845 1.00 50.82 ? 27 LEU L CG 1 ATOM 227 C CD1 . LEU A 1 31 D -16.343 -4.113 54.362 1.00 51.64 ? 27 LEU L CD1 1 ATOM 228 C CD2 . LEU A 1 31 D -14.623 -3.646 56.093 1.00 53.26 ? 27 LEU L CD2 1 ATOM 229 N N . SER A 1 32 E -19.708 -4.985 56.995 1.00 66.31 ? 27 SER L N 1 ATOM 230 C CA . SER A 1 32 E -20.414 -5.891 57.886 1.00 68.25 ? 27 SER L CA 1 ATOM 231 C C . SER A 1 32 E -19.678 -6.309 59.157 1.00 71.66 ? 27 SER L C 1 ATOM 232 O O . SER A 1 32 E -20.299 -6.586 60.180 1.00 74.33 ? 27 SER L O 1 ATOM 233 C CB . SER A 1 32 E -20.799 -7.127 57.070 1.00 68.56 ? 27 SER L CB 1 ATOM 234 O OG . SER A 1 32 E -20.159 -7.194 55.783 1.00 68.24 ? 27 SER L OG 1 ATOM 235 N N . ASP A 1 33 ? -18.340 -6.286 59.097 1.00 71.28 ? 28 ASP L N 1 ATOM 236 C CA . ASP A 1 33 ? -17.430 -6.692 60.163 1.00 72.51 ? 28 ASP L CA 1 ATOM 237 C C . ASP A 1 33 ? -17.551 -5.984 61.512 1.00 70.81 ? 28 ASP L C 1 ATOM 238 O O . ASP A 1 33 ? -16.925 -6.391 62.494 1.00 72.71 ? 28 ASP L O 1 ATOM 239 C CB . ASP A 1 33 ? -15.998 -6.496 59.677 1.00 78.59 ? 28 ASP L CB 1 ATOM 240 C CG . ASP A 1 33 ? -15.528 -5.031 59.715 1.00 86.12 ? 28 ASP L CG 1 ATOM 241 O OD1 . ASP A 1 33 ? -16.278 -4.121 59.348 1.00 89.57 ? 28 ASP L OD1 1 ATOM 242 O OD2 . ASP A 1 33 ? -14.405 -4.790 60.151 1.00 88.38 ? 28 ASP L OD2 1 ATOM 243 N N . GLY A 1 34 ? -18.248 -4.855 61.527 1.00 66.81 ? 29 GLY L N 1 ATOM 244 C CA . GLY A 1 34 ? -18.284 -3.997 62.687 1.00 67.37 ? 29 GLY L CA 1 ATOM 245 C C . GLY A 1 34 ? -18.500 -2.581 62.184 1.00 67.93 ? 29 GLY L C 1 ATOM 246 O O . GLY A 1 34 ? -19.408 -1.928 62.695 1.00 66.04 ? 29 GLY L O 1 ATOM 247 N N . ASP A 1 35 ? -17.675 -2.075 61.242 1.00 68.08 ? 30 ASP L N 1 ATOM 248 C CA . ASP A 1 35 ? -17.944 -0.810 60.564 1.00 65.18 ? 30 ASP L CA 1 ATOM 249 C C . ASP A 1 35 ? -16.947 -0.466 59.455 1.00 55.33 ? 30 ASP L C 1 ATOM 250 O O . ASP A 1 35 ? -16.101 -1.278 59.080 1.00 47.31 ? 30 ASP L O 1 ATOM 251 C CB . ASP A 1 35 ? -18.001 0.381 61.589 1.00 71.81 ? 30 ASP L CB 1 ATOM 252 C CG . ASP A 1 35 ? -19.333 1.166 61.533 1.00 74.31 ? 30 ASP L CG 1 ATOM 253 O OD1 . ASP A 1 35 ? -19.490 2.018 60.658 1.00 73.64 ? 30 ASP L OD1 1 ATOM 254 O OD2 . ASP A 1 35 ? -20.225 0.935 62.359 1.00 76.47 ? 30 ASP L OD2 1 ATOM 255 N N . THR A 1 36 ? -17.235 0.736 58.936 1.00 47.90 ? 31 THR L N 1 ATOM 256 C CA . THR A 1 36 ? -16.621 1.577 57.913 1.00 41.45 ? 31 THR L CA 1 ATOM 257 C C . THR A 1 36 ? -15.193 2.117 58.061 1.00 42.05 ? 31 THR L C 1 ATOM 258 O O . THR A 1 36 ? -14.765 2.541 59.140 1.00 49.49 ? 31 THR L O 1 ATOM 259 C CB . THR A 1 36 ? -17.584 2.758 57.744 1.00 36.78 ? 31 THR L CB 1 ATOM 260 O OG1 . THR A 1 36 ? -18.874 2.180 57.625 1.00 38.76 ? 31 THR L OG1 1 ATOM 261 C CG2 . THR A 1 36 ? -17.277 3.651 56.562 1.00 33.79 ? 31 THR L CG2 1 ATOM 262 N N . TYR A 1 37 ? -14.455 2.253 56.960 1.00 38.16 ? 32 TYR L N 1 ATOM 263 C CA . TYR A 1 37 ? -13.153 2.896 57.019 1.00 31.61 ? 32 TYR L CA 1 ATOM 264 C C . TYR A 1 37 ? -13.144 3.957 55.931 1.00 25.10 ? 32 TYR L C 1 ATOM 265 O O . TYR A 1 37 ? -12.591 3.794 54.843 1.00 14.62 ? 32 TYR L O 1 ATOM 266 C CB . TYR A 1 37 ? -11.987 1.948 56.742 1.00 36.93 ? 32 TYR L CB 1 ATOM 267 C CG . TYR A 1 37 ? -11.712 0.743 57.641 1.00 38.36 ? 32 TYR L CG 1 ATOM 268 C CD1 . TYR A 1 37 ? -12.537 -0.367 57.578 1.00 39.54 ? 32 TYR L CD1 1 ATOM 269 C CD2 . TYR A 1 37 ? -10.581 0.722 58.434 1.00 37.51 ? 32 TYR L CD2 1 ATOM 270 C CE1 . TYR A 1 37 ? -12.227 -1.501 58.284 1.00 34.54 ? 32 TYR L CE1 1 ATOM 271 C CE2 . TYR A 1 37 ? -10.269 -0.410 59.140 1.00 34.28 ? 32 TYR L CE2 1 ATOM 272 C CZ . TYR A 1 37 ? -11.096 -1.497 59.050 1.00 32.82 ? 32 TYR L CZ 1 ATOM 273 O OH . TYR A 1 37 ? -10.781 -2.642 59.717 1.00 36.29 ? 32 TYR L OH 1 ATOM 274 N N . LEU A 1 38 ? -13.827 5.042 56.266 1.00 25.05 ? 33 LEU L N 1 ATOM 275 C CA . LEU A 1 38 ? -13.932 6.248 55.463 1.00 19.43 ? 33 LEU L CA 1 ATOM 276 C C . LEU A 1 38 ? -13.035 7.187 56.215 1.00 17.48 ? 33 LEU L C 1 ATOM 277 O O . LEU A 1 38 ? -13.214 7.343 57.436 1.00 16.99 ? 33 LEU L O 1 ATOM 278 C CB . LEU A 1 38 ? -15.325 6.824 55.474 1.00 14.60 ? 33 LEU L CB 1 ATOM 279 C CG . LEU A 1 38 ? -15.784 7.991 54.573 1.00 13.69 ? 33 LEU L CG 1 ATOM 280 C CD1 . LEU A 1 38 ? -15.412 9.304 55.201 1.00 12.36 ? 33 LEU L CD1 1 ATOM 281 C CD2 . LEU A 1 38 ? -15.237 7.823 53.173 1.00 4.48 ? 33 LEU L CD2 1 ATOM 282 N N . GLU A 1 39 ? -12.076 7.700 55.449 1.00 15.11 ? 34 GLU L N 1 ATOM 283 C CA . GLU A 1 39 ? -11.051 8.619 55.895 1.00 19.15 ? 34 GLU L CA 1 ATOM 284 C C . GLU A 1 39 ? -11.114 10.024 55.287 1.00 20.42 ? 34 GLU L C 1 ATOM 285 O O . GLU A 1 39 ? -11.808 10.257 54.288 1.00 24.91 ? 34 GLU L O 1 ATOM 286 C CB . GLU A 1 39 ? -9.726 8.030 55.578 1.00 19.42 ? 34 GLU L CB 1 ATOM 287 C CG . GLU A 1 39 ? -9.288 6.954 56.524 1.00 26.44 ? 34 GLU L CG 1 ATOM 288 C CD . GLU A 1 39 ? -10.074 5.681 56.439 1.00 29.72 ? 34 GLU L CD 1 ATOM 289 O OE1 . GLU A 1 39 ? -10.267 5.171 55.340 1.00 35.50 ? 34 GLU L OE1 1 ATOM 290 O OE2 . GLU A 1 39 ? -10.508 5.218 57.484 1.00 35.31 ? 34 GLU L OE2 1 ATOM 291 N N . TRP A 1 40 ? -10.389 10.983 55.851 1.00 13.91 ? 35 TRP L N 1 ATOM 292 C CA . TRP A 1 40 ? -10.331 12.330 55.337 1.00 11.61 ? 35 TRP L CA 1 ATOM 293 C C . TRP A 1 40 ? -8.874 12.704 55.464 1.00 16.99 ? 35 TRP L C 1 ATOM 294 O O . TRP A 1 40 ? -8.316 12.630 56.569 1.00 18.72 ? 35 TRP L O 1 ATOM 295 C CB . TRP A 1 40 ? -11.156 13.257 56.182 1.00 12.00 ? 35 TRP L CB 1 ATOM 296 C CG . TRP A 1 40 ? -12.651 13.101 56.000 1.00 15.18 ? 35 TRP L CG 1 ATOM 297 C CD1 . TRP A 1 40 ? -13.432 12.486 56.934 1.00 12.67 ? 35 TRP L CD1 1 ATOM 298 C CD2 . TRP A 1 40 ? -13.382 13.539 54.928 1.00 20.23 ? 35 TRP L CD2 1 ATOM 299 N NE1 . TRP A 1 40 ? -14.661 12.524 56.466 1.00 12.85 ? 35 TRP L NE1 1 ATOM 300 C CE2 . TRP A 1 40 ? -14.671 13.135 55.276 1.00 15.36 ? 35 TRP L CE2 1 ATOM 301 C CE3 . TRP A 1 40 ? -13.139 14.213 53.739 1.00 21.68 ? 35 TRP L CE3 1 ATOM 302 C CZ2 . TRP A 1 40 ? -15.720 13.394 54.434 1.00 12.97 ? 35 TRP L CZ2 1 ATOM 303 C CZ3 . TRP A 1 40 ? -14.207 14.477 52.899 1.00 17.02 ? 35 TRP L CZ3 1 ATOM 304 C CH2 . TRP A 1 40 ? -15.476 14.067 53.250 1.00 14.38 ? 35 TRP L CH2 1 ATOM 305 N N . TYR A 1 41 ? -8.246 13.037 54.337 1.00 20.93 ? 36 TYR L N 1 ATOM 306 C CA . TYR A 1 41 ? -6.839 13.414 54.205 1.00 18.90 ? 36 TYR L CA 1 ATOM 307 C C . TYR A 1 41 ? -6.790 14.853 53.744 1.00 17.39 ? 36 TYR L C 1 ATOM 308 O O . TYR A 1 41 ? -7.592 15.229 52.868 1.00 16.78 ? 36 TYR L O 1 ATOM 309 C CB . TYR A 1 41 ? -6.089 12.627 53.129 1.00 20.51 ? 36 TYR L CB 1 ATOM 310 C CG . TYR A 1 41 ? -5.874 11.181 53.463 1.00 19.81 ? 36 TYR L CG 1 ATOM 311 C CD1 . TYR A 1 41 ? -4.906 10.838 54.382 1.00 23.98 ? 36 TYR L CD1 1 ATOM 312 C CD2 . TYR A 1 41 ? -6.664 10.236 52.862 1.00 19.12 ? 36 TYR L CD2 1 ATOM 313 C CE1 . TYR A 1 41 ? -4.739 9.511 54.710 1.00 29.04 ? 36 TYR L CE1 1 ATOM 314 C CE2 . TYR A 1 41 ? -6.505 8.906 53.190 1.00 26.33 ? 36 TYR L CE2 1 ATOM 315 C CZ . TYR A 1 41 ? -5.539 8.553 54.112 1.00 30.16 ? 36 TYR L CZ 1 ATOM 316 O OH . TYR A 1 41 ? -5.373 7.218 54.436 1.00 32.08 ? 36 TYR L OH 1 ATOM 317 N N . LEU A 1 42 ? -5.834 15.615 54.295 1.00 13.62 ? 37 LEU L N 1 ATOM 318 C CA . LEU A 1 42 ? -5.645 17.037 53.976 1.00 14.02 ? 37 LEU L CA 1 ATOM 319 C C . LEU A 1 42 ? -4.352 17.149 53.237 1.00 14.71 ? 37 LEU L C 1 ATOM 320 O O . LEU A 1 42 ? -3.398 16.508 53.668 1.00 17.09 ? 37 LEU L O 1 ATOM 321 C CB . LEU A 1 42 ? -5.515 17.930 55.225 1.00 12.52 ? 37 LEU L CB 1 ATOM 322 C CG . LEU A 1 42 ? -4.917 19.353 55.146 1.00 13.06 ? 37 LEU L CG 1 ATOM 323 C CD1 . LEU A 1 42 ? -5.769 20.215 54.243 1.00 15.36 ? 37 LEU L CD1 1 ATOM 324 C CD2 . LEU A 1 42 ? -4.882 20.010 56.502 1.00 5.02 ? 37 LEU L CD2 1 ATOM 325 N N . GLN A 1 43 ? -4.271 17.912 52.149 1.00 20.98 ? 38 GLN L N 1 ATOM 326 C CA . GLN A 1 43 ? -2.991 18.137 51.485 1.00 24.60 ? 38 GLN L CA 1 ATOM 327 C C . GLN A 1 43 ? -2.687 19.625 51.378 1.00 20.55 ? 38 GLN L C 1 ATOM 328 O O . GLN A 1 43 ? -3.108 20.317 50.446 1.00 20.65 ? 38 GLN L O 1 ATOM 329 C CB . GLN A 1 43 ? -3.005 17.506 50.101 1.00 22.98 ? 38 GLN L CB 1 ATOM 330 C CG . GLN A 1 43 ? -1.603 17.511 49.500 1.00 22.78 ? 38 GLN L CG 1 ATOM 331 C CD . GLN A 1 43 ? -1.490 16.748 48.192 1.00 25.26 ? 38 GLN L CD 1 ATOM 332 O OE1 . GLN A 1 43 ? -2.347 16.786 47.303 1.00 19.72 ? 38 GLN L OE1 1 ATOM 333 N NE2 . GLN A 1 43 ? -0.405 16.005 48.052 1.00 27.16 ? 38 GLN L NE2 1 ATOM 334 N N . LYS A 1 44 ? -1.996 20.121 52.405 1.00 22.74 ? 39 LYS L N 1 ATOM 335 C CA . LYS A 1 44 ? -1.649 21.539 52.482 1.00 24.61 ? 39 LYS L CA 1 ATOM 336 C C . LYS A 1 44 ? -0.640 21.762 51.385 1.00 22.89 ? 39 LYS L C 1 ATOM 337 O O . LYS A 1 44 ? 0.061 20.831 51.013 1.00 19.15 ? 39 LYS L O 1 ATOM 338 C CB . LYS A 1 44 ? -1.016 21.916 53.840 1.00 25.48 ? 39 LYS L CB 1 ATOM 339 C CG . LYS A 1 44 ? -1.840 21.845 55.119 1.00 21.80 ? 39 LYS L CG 1 ATOM 340 C CD . LYS A 1 44 ? -1.266 22.929 56.035 1.00 31.71 ? 39 LYS L CD 1 ATOM 341 C CE . LYS A 1 44 ? -1.652 22.890 57.548 1.00 41.26 ? 39 LYS L CE 1 ATOM 342 N NZ . LYS A 1 44 ? -0.839 22.024 58.413 1.00 35.58 ? 39 LYS L NZ 1 ATOM 343 N N . PRO A 1 45 ? -0.544 22.916 50.777 1.00 31.24 ? 40 PRO L N 1 ATOM 344 C CA . PRO A 1 45 ? 0.000 23.036 49.428 1.00 37.12 ? 40 PRO L CA 1 ATOM 345 C C . PRO A 1 45 ? 1.519 22.802 49.327 1.00 38.81 ? 40 PRO L C 1 ATOM 346 O O . PRO A 1 45 ? 2.301 23.391 50.074 1.00 38.97 ? 40 PRO L O 1 ATOM 347 C CB . PRO A 1 45 ? -0.487 24.420 49.022 1.00 38.29 ? 40 PRO L CB 1 ATOM 348 C CG . PRO A 1 45 ? -0.402 25.192 50.329 1.00 39.38 ? 40 PRO L CG 1 ATOM 349 C CD . PRO A 1 45 ? -0.917 24.190 51.364 1.00 33.59 ? 40 PRO L CD 1 ATOM 350 N N . GLY A 1 46 ? 1.964 21.928 48.413 1.00 41.49 ? 41 GLY L N 1 ATOM 351 C CA . GLY A 1 46 ? 3.381 21.596 48.302 1.00 43.92 ? 41 GLY L CA 1 ATOM 352 C C . GLY A 1 46 ? 3.835 20.624 49.407 1.00 46.30 ? 41 GLY L C 1 ATOM 353 O O . GLY A 1 46 ? 5.015 20.551 49.786 1.00 48.32 ? 41 GLY L O 1 ATOM 354 N N . GLN A 1 47 ? 2.903 19.835 49.956 1.00 39.46 ? 42 GLN L N 1 ATOM 355 C CA . GLN A 1 47 ? 3.223 18.863 50.982 1.00 26.83 ? 42 GLN L CA 1 ATOM 356 C C . GLN A 1 47 ? 2.467 17.624 50.586 1.00 18.63 ? 42 GLN L C 1 ATOM 357 O O . GLN A 1 47 ? 1.550 17.690 49.762 1.00 19.64 ? 42 GLN L O 1 ATOM 358 C CB . GLN A 1 47 ? 2.751 19.313 52.349 1.00 28.24 ? 42 GLN L CB 1 ATOM 359 C CG . GLN A 1 47 ? 3.292 20.654 52.788 1.00 32.44 ? 42 GLN L CG 1 ATOM 360 C CD . GLN A 1 47 ? 3.384 20.821 54.297 1.00 36.88 ? 42 GLN L CD 1 ATOM 361 O OE1 . GLN A 1 47 ? 3.624 21.907 54.812 1.00 46.31 ? 42 GLN L OE1 1 ATOM 362 N NE2 . GLN A 1 47 ? 3.247 19.826 55.146 1.00 37.23 ? 42 GLN L NE2 1 ATOM 363 N N . SER A 1 48 ? 2.839 16.484 51.138 1.00 15.87 ? 43 SER L N 1 ATOM 364 C CA . SER A 1 48 ? 2.182 15.213 50.873 1.00 10.59 ? 43 SER L CA 1 ATOM 365 C C . SER A 1 48 ? 0.984 15.069 51.775 1.00 4.92 ? 43 SER L C 1 ATOM 366 O O . SER A 1 48 ? 0.941 15.683 52.831 1.00 8.44 ? 43 SER L O 1 ATOM 367 C CB . SER A 1 48 ? 3.168 14.113 51.128 1.00 17.60 ? 43 SER L CB 1 ATOM 368 O OG . SER A 1 48 ? 4.241 14.490 51.996 1.00 29.56 ? 43 SER L OG 1 ATOM 369 N N . PRO A 1 49 ? -0.030 14.316 51.451 1.00 3.20 ? 44 PRO L N 1 ATOM 370 C CA . PRO A 1 49 ? -1.220 14.231 52.263 1.00 4.27 ? 44 PRO L CA 1 ATOM 371 C C . PRO A 1 49 ? -0.969 13.727 53.692 1.00 9.18 ? 44 PRO L C 1 ATOM 372 O O . PRO A 1 49 ? 0.025 13.021 53.916 1.00 14.55 ? 44 PRO L O 1 ATOM 373 C CB . PRO A 1 49 ? -2.082 13.349 51.436 1.00 3.32 ? 44 PRO L CB 1 ATOM 374 C CG . PRO A 1 49 ? -1.611 13.561 50.032 1.00 4.72 ? 44 PRO L CG 1 ATOM 375 C CD . PRO A 1 49 ? -0.120 13.515 50.260 1.00 4.29 ? 44 PRO L CD 1 ATOM 376 N N . LYS A 1 50 ? -1.851 14.085 54.655 1.00 8.91 ? 45 LYS L N 1 ATOM 377 C CA . LYS A 1 50 ? -1.829 13.659 56.055 1.00 3.52 ? 45 LYS L CA 1 ATOM 378 C C . LYS A 1 50 ? -3.236 13.279 56.492 1.00 3.52 ? 45 LYS L C 1 ATOM 379 O O . LYS A 1 50 ? -4.227 13.874 56.098 1.00 9.52 ? 45 LYS L O 1 ATOM 380 C CB . LYS A 1 50 ? -1.339 14.765 56.967 1.00 6.80 ? 45 LYS L CB 1 ATOM 381 C CG . LYS A 1 50 ? 0.200 14.954 56.938 1.00 23.74 ? 45 LYS L CG 1 ATOM 382 C CD . LYS A 1 50 ? 0.765 16.343 56.477 1.00 27.22 ? 45 LYS L CD 1 ATOM 383 C CE . LYS A 1 50 ? 2.261 16.297 56.046 1.00 30.01 ? 45 LYS L CE 1 ATOM 384 N NZ . LYS A 1 50 ? 3.241 16.412 57.121 1.00 32.08 ? 45 LYS L NZ 1 ATOM 385 N N . LEU A 1 51 ? -3.376 12.214 57.252 1.00 6.63 ? 46 LEU L N 1 ATOM 386 C CA . LEU A 1 51 ? -4.631 11.722 57.787 1.00 10.24 ? 46 LEU L CA 1 ATOM 387 C C . LEU A 1 51 ? -5.280 12.630 58.836 1.00 15.35 ? 46 LEU L C 1 ATOM 388 O O . LEU A 1 51 ? -4.695 12.841 59.901 1.00 14.89 ? 46 LEU L O 1 ATOM 389 C CB . LEU A 1 51 ? -4.351 10.371 58.400 1.00 7.74 ? 46 LEU L CB 1 ATOM 390 C CG . LEU A 1 51 ? -5.496 9.498 58.842 1.00 8.46 ? 46 LEU L CG 1 ATOM 391 C CD1 . LEU A 1 51 ? -6.341 9.128 57.620 1.00 6.13 ? 46 LEU L CD1 1 ATOM 392 C CD2 . LEU A 1 51 ? -4.954 8.236 59.481 1.00 2.00 ? 46 LEU L CD2 1 ATOM 393 N N . LEU A 1 52 ? -6.470 13.181 58.631 1.00 15.43 ? 47 LEU L N 1 ATOM 394 C CA . LEU A 1 52 ? -7.102 13.952 59.692 1.00 14.19 ? 47 LEU L CA 1 ATOM 395 C C . LEU A 1 52 ? -8.006 13.019 60.473 1.00 13.41 ? 47 LEU L C 1 ATOM 396 O O . LEU A 1 52 ? -7.954 12.937 61.692 1.00 10.91 ? 47 LEU L O 1 ATOM 397 C CB . LEU A 1 52 ? -7.975 15.072 59.170 1.00 14.43 ? 47 LEU L CB 1 ATOM 398 C CG . LEU A 1 52 ? -7.415 16.085 58.199 1.00 15.59 ? 47 LEU L CG 1 ATOM 399 C CD1 . LEU A 1 52 ? -8.557 16.957 57.795 1.00 14.58 ? 47 LEU L CD1 1 ATOM 400 C CD2 . LEU A 1 52 ? -6.317 16.931 58.801 1.00 13.50 ? 47 LEU L CD2 1 ATOM 401 N N . ILE A 1 53 ? -8.832 12.255 59.771 1.00 18.95 ? 48 ILE L N 1 ATOM 402 C CA . ILE A 1 53 ? -9.864 11.417 60.374 1.00 16.46 ? 48 ILE L CA 1 ATOM 403 C C . ILE A 1 53 ? -9.904 10.008 59.766 1.00 21.01 ? 48 ILE L C 1 ATOM 404 O O . ILE A 1 53 ? -9.860 9.822 58.537 1.00 22.51 ? 48 ILE L O 1 ATOM 405 C CB . ILE A 1 53 ? -11.172 12.241 60.188 1.00 6.16 ? 48 ILE L CB 1 ATOM 406 C CG1 . ILE A 1 53 ? -11.471 12.832 61.492 1.00 4.95 ? 48 ILE L CG1 1 ATOM 407 C CG2 . ILE A 1 53 ? -12.370 11.478 59.817 1.00 6.52 ? 48 ILE L CG2 1 ATOM 408 C CD1 . ILE A 1 53 ? -11.473 14.337 61.254 1.00 8.72 ? 48 ILE L CD1 1 ATOM 409 N N . TYR A 1 54 ? -9.974 8.995 60.618 1.00 20.18 ? 49 TYR L N 1 ATOM 410 C CA . TYR A 1 54 ? -10.076 7.637 60.152 1.00 20.86 ? 49 TYR L CA 1 ATOM 411 C C . TYR A 1 54 ? -11.265 6.996 60.840 1.00 25.48 ? 49 TYR L C 1 ATOM 412 O O . TYR A 1 54 ? -11.629 7.359 61.969 1.00 29.23 ? 49 TYR L O 1 ATOM 413 C CB . TYR A 1 54 ? -8.794 6.883 60.467 1.00 14.26 ? 49 TYR L CB 1 ATOM 414 C CG . TYR A 1 54 ? -8.549 6.674 61.925 1.00 10.31 ? 49 TYR L CG 1 ATOM 415 C CD1 . TYR A 1 54 ? -7.908 7.634 62.645 1.00 17.54 ? 49 TYR L CD1 1 ATOM 416 C CD2 . TYR A 1 54 ? -9.026 5.533 62.511 1.00 20.25 ? 49 TYR L CD2 1 ATOM 417 C CE1 . TYR A 1 54 ? -7.745 7.449 63.991 1.00 24.63 ? 49 TYR L CE1 1 ATOM 418 C CE2 . TYR A 1 54 ? -8.879 5.330 63.856 1.00 23.68 ? 49 TYR L CE2 1 ATOM 419 C CZ . TYR A 1 54 ? -8.240 6.303 64.567 1.00 25.18 ? 49 TYR L CZ 1 ATOM 420 O OH . TYR A 1 54 ? -8.118 6.120 65.906 1.00 32.31 ? 49 TYR L OH 1 ATOM 421 N N . LYS A 1 55 ? -11.870 6.016 60.154 1.00 26.89 ? 50 LYS L N 1 ATOM 422 C CA . LYS A 1 55 ? -13.065 5.313 60.607 1.00 24.46 ? 50 LYS L CA 1 ATOM 423 C C . LYS A 1 55 ? -14.133 6.328 61.013 1.00 26.91 ? 50 LYS L C 1 ATOM 424 O O . LYS A 1 55 ? -14.761 6.281 62.076 1.00 30.47 ? 50 LYS L O 1 ATOM 425 C CB . LYS A 1 55 ? -12.682 4.392 61.760 1.00 15.51 ? 50 LYS L CB 1 ATOM 426 C CG . LYS A 1 55 ? -11.663 3.487 61.141 1.00 17.73 ? 50 LYS L CG 1 ATOM 427 C CD . LYS A 1 55 ? -11.980 2.044 61.345 1.00 23.74 ? 50 LYS L CD 1 ATOM 428 C CE . LYS A 1 55 ? -11.507 1.588 62.705 1.00 31.73 ? 50 LYS L CE 1 ATOM 429 N NZ . LYS A 1 55 ? -11.423 0.136 62.722 1.00 37.36 ? 50 LYS L NZ 1 ATOM 430 N N . VAL A 1 56 ? -14.225 7.302 60.097 1.00 24.35 ? 51 VAL L N 1 ATOM 431 C CA . VAL A 1 56 ? -15.127 8.439 60.050 1.00 27.20 ? 51 VAL L CA 1 ATOM 432 C C . VAL A 1 56 ? -15.224 9.403 61.243 1.00 25.23 ? 51 VAL L C 1 ATOM 433 O O . VAL A 1 56 ? -15.295 10.620 61.038 1.00 26.82 ? 51 VAL L O 1 ATOM 434 C CB . VAL A 1 56 ? -16.526 7.828 59.601 1.00 32.30 ? 51 VAL L CB 1 ATOM 435 C CG1 . VAL A 1 56 ? -17.375 7.223 60.699 1.00 32.64 ? 51 VAL L CG1 1 ATOM 436 C CG2 . VAL A 1 56 ? -17.286 8.959 58.968 1.00 37.77 ? 51 VAL L CG2 1 ATOM 437 N N . SER A 1 57 ? -15.143 9.003 62.490 1.00 23.40 ? 52 SER L N 1 ATOM 438 C CA . SER A 1 57 ? -15.244 9.938 63.597 1.00 27.51 ? 52 SER L CA 1 ATOM 439 C C . SER A 1 57 ? -13.920 10.364 64.238 1.00 26.13 ? 52 SER L C 1 ATOM 440 O O . SER A 1 57 ? -13.797 11.487 64.743 1.00 19.46 ? 52 SER L O 1 ATOM 441 C CB . SER A 1 57 ? -16.116 9.313 64.668 1.00 35.15 ? 52 SER L CB 1 ATOM 442 O OG . SER A 1 57 ? -17.086 8.383 64.159 1.00 49.70 ? 52 SER L OG 1 ATOM 443 N N . ASN A 1 58 ? -12.918 9.465 64.205 1.00 21.40 ? 53 ASN L N 1 ATOM 444 C CA . ASN A 1 58 ? -11.715 9.648 65.009 1.00 27.09 ? 53 ASN L CA 1 ATOM 445 C C . ASN A 1 58 ? -10.562 10.348 64.371 1.00 28.57 ? 53 ASN L C 1 ATOM 446 O O . ASN A 1 58 ? -10.059 9.960 63.310 1.00 29.08 ? 53 ASN L O 1 ATOM 447 C CB . ASN A 1 58 ? -11.107 8.358 65.491 1.00 30.34 ? 53 ASN L CB 1 ATOM 448 C CG . ASN A 1 58 ? -12.160 7.385 65.942 1.00 31.20 ? 53 ASN L CG 1 ATOM 449 O OD1 . ASN A 1 58 ? -12.534 7.289 67.114 1.00 33.06 ? 53 ASN L OD1 1 ATOM 450 N ND2 . ASN A 1 58 ? -12.694 6.693 64.948 1.00 27.37 ? 53 ASN L ND2 1 ATOM 451 N N . ARG A 1 59 ? -10.108 11.342 65.112 1.00 25.65 ? 54 ARG L N 1 ATOM 452 C CA . ARG A 1 59 ? -8.993 12.119 64.643 1.00 23.98 ? 54 ARG L CA 1 ATOM 453 C C . ARG A 1 59 ? -7.654 11.430 64.890 1.00 21.71 ? 54 ARG L C 1 ATOM 454 O O . ARG A 1 59 ? -7.372 10.785 65.904 1.00 19.88 ? 54 ARG L O 1 ATOM 455 C CB . ARG A 1 59 ? -9.045 13.455 65.318 1.00 23.00 ? 54 ARG L CB 1 ATOM 456 C CG . ARG A 1 59 ? -10.312 14.199 64.953 1.00 27.26 ? 54 ARG L CG 1 ATOM 457 C CD . ARG A 1 59 ? -10.270 15.561 65.619 1.00 31.72 ? 54 ARG L CD 1 ATOM 458 N NE . ARG A 1 59 ? -10.612 15.408 67.011 1.00 32.99 ? 54 ARG L NE 1 ATOM 459 C CZ . ARG A 1 59 ? -11.886 15.503 67.408 1.00 39.98 ? 54 ARG L CZ 1 ATOM 460 N NH1 . ARG A 1 59 ? -12.887 15.846 66.577 1.00 36.33 ? 54 ARG L NH1 1 ATOM 461 N NH2 . ARG A 1 59 ? -12.156 15.289 68.698 1.00 45.62 ? 54 ARG L NH2 1 ATOM 462 N N . PHE A 1 60 ? -6.801 11.500 63.898 1.00 19.83 ? 55 PHE L N 1 ATOM 463 C CA . PHE A 1 60 ? -5.496 10.956 64.047 1.00 20.02 ? 55 PHE L CA 1 ATOM 464 C C . PHE A 1 60 ? -4.834 11.852 65.086 1.00 22.92 ? 55 PHE L C 1 ATOM 465 O O . PHE A 1 60 ? -5.320 12.937 65.428 1.00 19.59 ? 55 PHE L O 1 ATOM 466 C CB . PHE A 1 60 ? -4.815 11.021 62.701 1.00 20.23 ? 55 PHE L CB 1 ATOM 467 C CG . PHE A 1 60 ? -3.494 10.254 62.627 1.00 19.34 ? 55 PHE L CG 1 ATOM 468 C CD1 . PHE A 1 60 ? -3.483 8.877 62.691 1.00 17.63 ? 55 PHE L CD1 1 ATOM 469 C CD2 . PHE A 1 60 ? -2.308 10.933 62.438 1.00 18.95 ? 55 PHE L CD2 1 ATOM 470 C CE1 . PHE A 1 60 ? -2.298 8.193 62.558 1.00 17.92 ? 55 PHE L CE1 1 ATOM 471 C CE2 . PHE A 1 60 ? -1.126 10.243 62.302 1.00 18.97 ? 55 PHE L CE2 1 ATOM 472 C CZ . PHE A 1 60 ? -1.116 8.874 62.361 1.00 16.37 ? 55 PHE L CZ 1 ATOM 473 N N . SER A 1 61 ? -3.711 11.410 65.630 1.00 28.46 ? 56 SER L N 1 ATOM 474 C CA . SER A 1 61 ? -3.049 12.194 66.659 1.00 35.95 ? 56 SER L CA 1 ATOM 475 C C . SER A 1 61 ? -2.481 13.501 66.088 1.00 31.50 ? 56 SER L C 1 ATOM 476 O O . SER A 1 61 ? -1.981 13.527 64.961 1.00 31.99 ? 56 SER L O 1 ATOM 477 C CB . SER A 1 61 ? -1.970 11.290 67.292 1.00 38.87 ? 56 SER L CB 1 ATOM 478 O OG . SER A 1 61 ? -1.241 10.607 66.281 1.00 44.70 ? 56 SER L OG 1 ATOM 479 N N . GLY A 1 62 ? -2.606 14.619 66.800 1.00 26.63 ? 57 GLY L N 1 ATOM 480 C CA . GLY A 1 62 ? -2.096 15.880 66.298 1.00 22.91 ? 57 GLY L CA 1 ATOM 481 C C . GLY A 1 62 ? -3.277 16.746 65.932 1.00 21.55 ? 57 GLY L C 1 ATOM 482 O O . GLY A 1 62 ? -3.436 17.848 66.467 1.00 22.27 ? 57 GLY L O 1 ATOM 483 N N . VAL A 1 63 ? -4.119 16.149 65.073 1.00 17.75 ? 58 VAL L N 1 ATOM 484 C CA . VAL A 1 63 ? -5.365 16.732 64.570 1.00 14.93 ? 58 VAL L CA 1 ATOM 485 C C . VAL A 1 63 ? -6.216 17.343 65.675 1.00 16.81 ? 58 VAL L C 1 ATOM 486 O O . VAL A 1 63 ? -6.483 16.634 66.629 1.00 25.60 ? 58 VAL L O 1 ATOM 487 C CB . VAL A 1 63 ? -6.203 15.669 63.863 1.00 10.69 ? 58 VAL L CB 1 ATOM 488 C CG1 . VAL A 1 63 ? -7.404 16.294 63.185 1.00 11.81 ? 58 VAL L CG1 1 ATOM 489 C CG2 . VAL A 1 63 ? -5.373 15.028 62.788 1.00 14.50 ? 58 VAL L CG2 1 ATOM 490 N N . PRO A 1 64 ? -6.657 18.598 65.660 1.00 20.51 ? 59 PRO L N 1 ATOM 491 C CA . PRO A 1 64 ? -7.441 19.192 66.730 1.00 20.23 ? 59 PRO L CA 1 ATOM 492 C C . PRO A 1 64 ? -8.929 19.056 66.574 1.00 16.28 ? 59 PRO L C 1 ATOM 493 O O . PRO A 1 64 ? -9.487 18.992 65.485 1.00 15.72 ? 59 PRO L O 1 ATOM 494 C CB . PRO A 1 64 ? -7.021 20.622 66.760 1.00 26.45 ? 59 PRO L CB 1 ATOM 495 C CG . PRO A 1 64 ? -6.877 20.898 65.253 1.00 26.98 ? 59 PRO L CG 1 ATOM 496 C CD . PRO A 1 64 ? -6.243 19.623 64.699 1.00 22.66 ? 59 PRO L CD 1 ATOM 497 N N . ASP A 1 65 ? -9.590 19.049 67.707 1.00 25.62 ? 60 ASP L N 1 ATOM 498 C CA . ASP A 1 65 ? -11.035 19.003 67.734 1.00 34.74 ? 60 ASP L CA 1 ATOM 499 C C . ASP A 1 65 ? -11.363 20.400 67.309 1.00 31.89 ? 60 ASP L C 1 ATOM 500 O O . ASP A 1 65 ? -10.850 21.397 67.809 1.00 39.33 ? 60 ASP L O 1 ATOM 501 C CB . ASP A 1 65 ? -11.545 18.673 69.153 1.00 47.14 ? 60 ASP L CB 1 ATOM 502 C CG . ASP A 1 65 ? -11.099 19.479 70.379 1.00 54.45 ? 60 ASP L CG 1 ATOM 503 O OD1 . ASP A 1 65 ? -9.926 19.870 70.487 1.00 56.71 ? 60 ASP L OD1 1 ATOM 504 O OD2 . ASP A 1 65 ? -11.957 19.681 71.245 1.00 56.55 ? 60 ASP L OD2 1 ATOM 505 N N . ARG A 1 66 ? -11.949 20.280 66.146 1.00 27.30 ? 61 ARG L N 1 ATOM 506 C CA . ARG A 1 66 ? -12.286 21.379 65.263 1.00 19.87 ? 61 ARG L CA 1 ATOM 507 C C . ARG A 1 66 ? -12.617 20.595 64.021 1.00 17.69 ? 61 ARG L C 1 ATOM 508 O O . ARG A 1 66 ? -13.598 20.861 63.336 1.00 20.87 ? 61 ARG L O 1 ATOM 509 C CB . ARG A 1 66 ? -11.121 22.265 64.923 1.00 15.01 ? 61 ARG L CB 1 ATOM 510 C CG . ARG A 1 66 ? -11.251 23.612 65.566 1.00 14.15 ? 61 ARG L CG 1 ATOM 511 C CD . ARG A 1 66 ? -10.020 24.437 65.258 1.00 16.62 ? 61 ARG L CD 1 ATOM 512 N NE . ARG A 1 66 ? -9.910 24.667 63.831 1.00 22.42 ? 61 ARG L NE 1 ATOM 513 C CZ . ARG A 1 66 ? -8.740 24.883 63.240 1.00 23.33 ? 61 ARG L CZ 1 ATOM 514 N NH1 . ARG A 1 66 ? -7.613 25.050 63.917 1.00 21.48 ? 61 ARG L NH1 1 ATOM 515 N NH2 . ARG A 1 66 ? -8.712 24.976 61.931 1.00 19.85 ? 61 ARG L NH2 1 ATOM 516 N N . PHE A 1 67 ? -11.761 19.638 63.700 1.00 16.15 ? 62 PHE L N 1 ATOM 517 C CA . PHE A 1 67 ? -12.024 18.744 62.605 1.00 16.99 ? 62 PHE L CA 1 ATOM 518 C C . PHE A 1 67 ? -12.956 17.681 63.148 1.00 20.40 ? 62 PHE L C 1 ATOM 519 O O . PHE A 1 67 ? -12.671 17.165 64.234 1.00 20.78 ? 62 PHE L O 1 ATOM 520 C CB . PHE A 1 67 ? -10.711 18.184 62.156 1.00 8.57 ? 62 PHE L CB 1 ATOM 521 C CG . PHE A 1 67 ? -9.975 19.229 61.348 1.00 5.67 ? 62 PHE L CG 1 ATOM 522 C CD1 . PHE A 1 67 ? -10.205 19.313 59.991 1.00 9.16 ? 62 PHE L CD1 1 ATOM 523 C CD2 . PHE A 1 67 ? -9.044 20.034 61.953 1.00 4.12 ? 62 PHE L CD2 1 ATOM 524 C CE1 . PHE A 1 67 ? -9.478 20.206 59.237 1.00 12.15 ? 62 PHE L CE1 1 ATOM 525 C CE2 . PHE A 1 67 ? -8.326 20.923 61.192 1.00 5.37 ? 62 PHE L CE2 1 ATOM 526 C CZ . PHE A 1 67 ? -8.537 21.010 59.838 1.00 9.22 ? 62 PHE L CZ 1 ATOM 527 N N . SER A 1 68 ? -14.093 17.414 62.492 1.00 20.85 ? 63 SER L N 1 ATOM 528 C CA . SER A 1 68 ? -15.026 16.405 62.955 1.00 28.49 ? 63 SER L CA 1 ATOM 529 C C . SER A 1 68 ? -15.597 15.665 61.751 1.00 31.42 ? 63 SER L C 1 ATOM 530 O O . SER A 1 68 ? -16.059 16.302 60.801 1.00 32.49 ? 63 SER L O 1 ATOM 531 C CB . SER A 1 68 ? -16.128 17.094 63.745 1.00 32.42 ? 63 SER L CB 1 ATOM 532 O OG . SER A 1 68 ? -15.596 18.046 64.670 1.00 40.23 ? 63 SER L OG 1 ATOM 533 N N . GLY A 1 69 ? -15.556 14.326 61.753 1.00 33.89 ? 64 GLY L N 1 ATOM 534 C CA . GLY A 1 69 ? -15.997 13.522 60.617 1.00 33.70 ? 64 GLY L CA 1 ATOM 535 C C . GLY A 1 69 ? -17.375 12.964 60.890 1.00 32.13 ? 64 GLY L C 1 ATOM 536 O O . GLY A 1 69 ? -17.805 13.087 62.033 1.00 36.17 ? 64 GLY L O 1 ATOM 537 N N . SER A 1 70 ? -18.100 12.337 59.962 1.00 30.38 ? 65 SER L N 1 ATOM 538 C CA . SER A 1 70 ? -19.459 11.879 60.202 1.00 22.94 ? 65 SER L CA 1 ATOM 539 C C . SER A 1 70 ? -20.127 11.244 58.991 1.00 28.80 ? 65 SER L C 1 ATOM 540 O O . SER A 1 70 ? -19.674 11.344 57.837 1.00 24.51 ? 65 SER L O 1 ATOM 541 C CB . SER A 1 70 ? -20.344 13.024 60.619 1.00 26.25 ? 65 SER L CB 1 ATOM 542 O OG . SER A 1 70 ? -20.483 12.914 62.011 1.00 38.49 ? 65 SER L OG 1 ATOM 543 N N . GLY A 1 71 ? -21.286 10.674 59.323 1.00 30.94 ? 66 GLY L N 1 ATOM 544 C CA . GLY A 1 71 ? -22.144 9.966 58.402 1.00 29.58 ? 66 GLY L CA 1 ATOM 545 C C . GLY A 1 71 ? -22.031 8.494 58.777 1.00 28.86 ? 66 GLY L C 1 ATOM 546 O O . GLY A 1 71 ? -21.601 8.150 59.888 1.00 28.34 ? 66 GLY L O 1 ATOM 547 N N . SER A 1 72 ? -22.348 7.631 57.826 1.00 29.34 ? 67 SER L N 1 ATOM 548 C CA . SER A 1 72 ? -22.328 6.186 58.000 1.00 32.67 ? 67 SER L CA 1 ATOM 549 C C . SER A 1 72 ? -22.749 5.594 56.669 1.00 34.77 ? 67 SER L C 1 ATOM 550 O O . SER A 1 72 ? -23.432 6.293 55.889 1.00 37.36 ? 67 SER L O 1 ATOM 551 C CB . SER A 1 72 ? -23.328 5.774 59.058 1.00 32.49 ? 67 SER L CB 1 ATOM 552 O OG . SER A 1 72 ? -24.530 6.539 58.946 1.00 33.16 ? 67 SER L OG 1 ATOM 553 N N . GLY A 1 73 ? -22.392 4.350 56.361 1.00 27.25 ? 68 GLY L N 1 ATOM 554 C CA . GLY A 1 73 ? -22.914 3.748 55.139 1.00 26.93 ? 68 GLY L CA 1 ATOM 555 C C . GLY A 1 73 ? -22.634 4.460 53.816 1.00 27.23 ? 68 GLY L C 1 ATOM 556 O O . GLY A 1 73 ? -21.710 4.051 53.120 1.00 36.18 ? 68 GLY L O 1 ATOM 557 N N . THR A 1 74 ? -23.324 5.511 53.408 1.00 26.27 ? 69 THR L N 1 ATOM 558 C CA . THR A 1 74 ? -23.045 6.082 52.106 1.00 31.38 ? 69 THR L CA 1 ATOM 559 C C . THR A 1 74 ? -22.781 7.589 52.037 1.00 35.10 ? 69 THR L C 1 ATOM 560 O O . THR A 1 74 ? -21.999 8.027 51.172 1.00 34.32 ? 69 THR L O 1 ATOM 561 C CB . THR A 1 74 ? -24.242 5.546 51.244 1.00 31.09 ? 69 THR L CB 1 ATOM 562 O OG1 . THR A 1 74 ? -23.858 4.174 51.070 1.00 32.71 ? 69 THR L OG1 1 ATOM 563 C CG2 . THR A 1 74 ? -24.530 6.189 49.886 1.00 27.51 ? 69 THR L CG2 1 ATOM 564 N N . ASP A 1 75 ? -23.365 8.395 52.940 1.00 39.97 ? 70 ASP L N 1 ATOM 565 C CA . ASP A 1 75 ? -23.133 9.841 52.983 1.00 46.42 ? 70 ASP L CA 1 ATOM 566 C C . ASP A 1 75 ? -22.077 10.072 54.053 1.00 45.27 ? 70 ASP L C 1 ATOM 567 O O . ASP A 1 75 ? -22.206 9.471 55.135 1.00 47.89 ? 70 ASP L O 1 ATOM 568 C CB . ASP A 1 75 ? -24.388 10.641 53.395 1.00 56.06 ? 70 ASP L CB 1 ATOM 569 C CG . ASP A 1 75 ? -24.134 12.095 53.850 1.00 64.10 ? 70 ASP L CG 1 ATOM 570 O OD1 . ASP A 1 75 ? -23.817 12.327 55.031 1.00 64.76 ? 70 ASP L OD1 1 ATOM 571 O OD2 . ASP A 1 75 ? -24.260 12.997 53.016 1.00 68.36 ? 70 ASP L OD2 1 ATOM 572 N N . PHE A 1 76 ? -21.075 10.928 53.812 1.00 38.11 ? 71 PHE L N 1 ATOM 573 C CA . PHE A 1 76 ? -20.051 11.207 54.803 1.00 30.59 ? 71 PHE L CA 1 ATOM 574 C C . PHE A 1 76 ? -19.775 12.699 54.820 1.00 24.40 ? 71 PHE L C 1 ATOM 575 O O . PHE A 1 76 ? -19.833 13.330 53.767 1.00 25.46 ? 71 PHE L O 1 ATOM 576 C CB . PHE A 1 76 ? -18.827 10.357 54.435 1.00 26.28 ? 71 PHE L CB 1 ATOM 577 C CG . PHE A 1 76 ? -19.106 8.879 54.722 1.00 20.49 ? 71 PHE L CG 1 ATOM 578 C CD1 . PHE A 1 76 ? -19.119 8.425 56.038 1.00 16.86 ? 71 PHE L CD1 1 ATOM 579 C CD2 . PHE A 1 76 ? -19.381 7.997 53.685 1.00 18.55 ? 71 PHE L CD2 1 ATOM 580 C CE1 . PHE A 1 76 ? -19.404 7.103 56.343 1.00 13.83 ? 71 PHE L CE1 1 ATOM 581 C CE2 . PHE A 1 76 ? -19.668 6.673 53.998 1.00 22.31 ? 71 PHE L CE2 1 ATOM 582 C CZ . PHE A 1 76 ? -19.682 6.225 55.322 1.00 18.39 ? 71 PHE L CZ 1 ATOM 583 N N . THR A 1 77 ? -19.544 13.327 55.963 1.00 20.70 ? 72 THR L N 1 ATOM 584 C CA . THR A 1 77 ? -19.352 14.774 56.098 1.00 28.16 ? 72 THR L CA 1 ATOM 585 C C . THR A 1 77 ? -18.070 15.130 56.898 1.00 32.21 ? 72 THR L C 1 ATOM 586 O O . THR A 1 77 ? -17.601 14.296 57.696 1.00 39.45 ? 72 THR L O 1 ATOM 587 C CB . THR A 1 77 ? -20.635 15.266 56.773 1.00 31.56 ? 72 THR L CB 1 ATOM 588 O OG1 . THR A 1 77 ? -21.609 15.046 55.775 1.00 37.46 ? 72 THR L OG1 1 ATOM 589 C CG2 . THR A 1 77 ? -20.688 16.719 57.212 1.00 34.65 ? 72 THR L CG2 1 ATOM 590 N N . LEU A 1 78 ? -17.444 16.300 56.739 1.00 27.09 ? 73 LEU L N 1 ATOM 591 C CA . LEU A 1 78 ? -16.273 16.691 57.516 1.00 20.98 ? 73 LEU L CA 1 ATOM 592 C C . LEU A 1 78 ? -16.549 18.131 57.781 1.00 22.91 ? 73 LEU L C 1 ATOM 593 O O . LEU A 1 78 ? -16.822 18.921 56.865 1.00 32.55 ? 73 LEU L O 1 ATOM 594 C CB . LEU A 1 78 ? -14.997 16.648 56.744 1.00 22.81 ? 73 LEU L CB 1 ATOM 595 C CG . LEU A 1 78 ? -13.771 17.096 57.493 1.00 22.45 ? 73 LEU L CG 1 ATOM 596 C CD1 . LEU A 1 78 ? -13.449 16.160 58.646 1.00 18.20 ? 73 LEU L CD1 1 ATOM 597 C CD2 . LEU A 1 78 ? -12.652 17.161 56.484 1.00 23.15 ? 73 LEU L CD2 1 ATOM 598 N N . LYS A 1 79 ? -16.510 18.485 59.028 1.00 20.70 ? 74 LYS L N 1 ATOM 599 C CA . LYS A 1 79 ? -16.918 19.809 59.378 1.00 24.91 ? 74 LYS L CA 1 ATOM 600 C C . LYS A 1 79 ? -15.702 20.328 60.063 1.00 23.84 ? 74 LYS L C 1 ATOM 601 O O . LYS A 1 79 ? -15.132 19.583 60.863 1.00 26.11 ? 74 LYS L O 1 ATOM 602 C CB . LYS A 1 79 ? -18.166 19.723 60.297 1.00 33.66 ? 74 LYS L CB 1 ATOM 603 C CG . LYS A 1 79 ? -19.448 19.286 59.524 1.00 42.20 ? 74 LYS L CG 1 ATOM 604 C CD . LYS A 1 79 ? -20.595 18.670 60.351 1.00 50.85 ? 74 LYS L CD 1 ATOM 605 C CE . LYS A 1 79 ? -21.693 19.628 60.865 1.00 58.11 ? 74 LYS L CE 1 ATOM 606 N NZ . LYS A 1 79 ? -22.679 19.968 59.847 1.00 58.67 ? 74 LYS L NZ 1 ATOM 607 N N . ILE A 1 80 ? -15.228 21.502 59.644 1.00 25.44 ? 75 ILE L N 1 ATOM 608 C CA . ILE A 1 80 ? -14.110 22.193 60.297 1.00 30.29 ? 75 ILE L CA 1 ATOM 609 C C . ILE A 1 80 ? -14.864 23.277 61.060 1.00 30.84 ? 75 ILE L C 1 ATOM 610 O O . ILE A 1 80 ? -15.559 24.086 60.445 1.00 36.87 ? 75 ILE L O 1 ATOM 611 C CB . ILE A 1 80 ? -13.093 22.836 59.271 1.00 27.06 ? 75 ILE L CB 1 ATOM 612 C CG1 . ILE A 1 80 ? -12.684 21.843 58.173 1.00 29.43 ? 75 ILE L CG1 1 ATOM 613 C CG2 . ILE A 1 80 ? -11.817 23.194 60.008 1.00 23.77 ? 75 ILE L CG2 1 ATOM 614 C CD1 . ILE A 1 80 ? -11.683 22.359 57.117 1.00 27.91 ? 75 ILE L CD1 1 ATOM 615 N N . SER A 1 81 ? -14.806 23.322 62.377 1.00 32.31 ? 76 SER L N 1 ATOM 616 C CA . SER A 1 81 ? -15.653 24.218 63.127 1.00 30.91 ? 76 SER L CA 1 ATOM 617 C C . SER A 1 81 ? -15.330 25.670 63.015 1.00 27.87 ? 76 SER L C 1 ATOM 618 O O . SER A 1 81 ? -16.261 26.437 62.865 1.00 33.76 ? 76 SER L O 1 ATOM 619 C CB . SER A 1 81 ? -15.654 23.828 64.599 1.00 35.48 ? 76 SER L CB 1 ATOM 620 O OG . SER A 1 81 ? -14.330 23.683 65.127 1.00 44.72 ? 76 SER L OG 1 ATOM 621 N N . ARG A 1 82 ? -14.105 26.134 63.141 1.00 28.18 ? 77 ARG L N 1 ATOM 622 C CA . ARG A 1 82 ? -13.888 27.560 62.989 1.00 34.16 ? 77 ARG L CA 1 ATOM 623 C C . ARG A 1 82 ? -12.480 27.648 62.474 1.00 31.21 ? 77 ARG L C 1 ATOM 624 O O . ARG A 1 82 ? -11.489 27.252 63.107 1.00 30.54 ? 77 ARG L O 1 ATOM 625 C CB . ARG A 1 82 ? -14.114 28.300 64.338 1.00 38.51 ? 77 ARG L CB 1 ATOM 626 C CG . ARG A 1 82 ? -13.662 27.686 65.655 1.00 48.41 ? 77 ARG L CG 1 ATOM 627 C CD . ARG A 1 82 ? -14.672 27.931 66.804 1.00 48.29 ? 77 ARG L CD 1 ATOM 628 N NE . ARG A 1 82 ? -15.196 26.659 67.304 1.00 50.15 ? 77 ARG L NE 1 ATOM 629 C CZ . ARG A 1 82 ? -14.471 25.805 68.050 1.00 51.56 ? 77 ARG L CZ 1 ATOM 630 N NH1 . ARG A 1 82 ? -13.243 26.124 68.485 1.00 56.18 ? 77 ARG L NH1 1 ATOM 631 N NH2 . ARG A 1 82 ? -15.000 24.626 68.401 1.00 50.66 ? 77 ARG L NH2 1 ATOM 632 N N . VAL A 1 83 ? -12.557 28.023 61.189 1.00 22.31 ? 78 VAL L N 1 ATOM 633 C CA . VAL A 1 83 ? -11.424 27.951 60.306 1.00 13.54 ? 78 VAL L CA 1 ATOM 634 C C . VAL A 1 83 ? -10.356 28.942 60.649 1.00 15.06 ? 78 VAL L C 1 ATOM 635 O O . VAL A 1 83 ? -10.630 30.092 60.957 1.00 17.96 ? 78 VAL L O 1 ATOM 636 C CB . VAL A 1 83 ? -11.931 28.123 58.868 1.00 8.06 ? 78 VAL L CB 1 ATOM 637 C CG1 . VAL A 1 83 ? -10.819 27.989 57.841 1.00 2.08 ? 78 VAL L CG1 1 ATOM 638 C CG2 . VAL A 1 83 ? -12.863 26.971 58.573 1.00 8.50 ? 78 VAL L CG2 1 ATOM 639 N N . GLU A 1 84 ? -9.150 28.406 60.743 1.00 19.32 ? 79 GLU L N 1 ATOM 640 C CA . GLU A 1 84 ? -7.919 29.145 60.966 1.00 16.97 ? 79 GLU L CA 1 ATOM 641 C C . GLU A 1 84 ? -7.224 29.216 59.636 1.00 17.25 ? 79 GLU L C 1 ATOM 642 O O . GLU A 1 84 ? -7.444 28.396 58.723 1.00 13.71 ? 79 GLU L O 1 ATOM 643 C CB . GLU A 1 84 ? -7.018 28.432 61.946 1.00 17.39 ? 79 GLU L CB 1 ATOM 644 C CG . GLU A 1 84 ? -7.302 28.915 63.350 1.00 22.73 ? 79 GLU L CG 1 ATOM 645 C CD . GLU A 1 84 ? -6.574 28.157 64.426 1.00 30.38 ? 79 GLU L CD 1 ATOM 646 O OE1 . GLU A 1 84 ? -5.381 27.860 64.286 1.00 34.22 ? 79 GLU L OE1 1 ATOM 647 O OE2 . GLU A 1 84 ? -7.230 27.861 65.416 1.00 31.18 ? 79 GLU L OE2 1 ATOM 648 N N . ALA A 1 85 ? -6.316 30.181 59.562 1.00 15.33 ? 80 ALA L N 1 ATOM 649 C CA . ALA A 1 85 ? -5.704 30.465 58.284 1.00 13.07 ? 80 ALA L CA 1 ATOM 650 C C . ALA A 1 85 ? -4.909 29.346 57.704 1.00 14.23 ? 80 ALA L C 1 ATOM 651 O O . ALA A 1 85 ? -4.763 29.222 56.492 1.00 22.46 ? 80 ALA L O 1 ATOM 652 C CB . ALA A 1 85 ? -4.788 31.616 58.390 1.00 21.58 ? 80 ALA L CB 1 ATOM 653 N N . GLU A 1 86 ? -4.476 28.436 58.545 1.00 10.52 ? 81 GLU L N 1 ATOM 654 C CA . GLU A 1 86 ? -3.617 27.420 58.026 1.00 16.18 ? 81 GLU L CA 1 ATOM 655 C C . GLU A 1 86 ? -4.433 26.144 57.897 1.00 15.63 ? 81 GLU L C 1 ATOM 656 O O . GLU A 1 86 ? -4.096 25.065 58.381 1.00 18.78 ? 81 GLU L O 1 ATOM 657 C CB . GLU A 1 86 ? -2.404 27.293 58.962 1.00 25.60 ? 81 GLU L CB 1 ATOM 658 C CG . GLU A 1 86 ? -2.161 28.395 60.025 1.00 36.10 ? 81 GLU L CG 1 ATOM 659 C CD . GLU A 1 86 ? -3.101 28.351 61.251 1.00 47.09 ? 81 GLU L CD 1 ATOM 660 O OE1 . GLU A 1 86 ? -3.430 27.266 61.760 1.00 48.92 ? 81 GLU L OE1 1 ATOM 661 O OE2 . GLU A 1 86 ? -3.513 29.421 61.713 1.00 53.47 ? 81 GLU L OE2 1 ATOM 662 N N . ASP A 1 87 ? -5.602 26.269 57.275 1.00 17.21 ? 82 ASP L N 1 ATOM 663 C CA . ASP A 1 87 ? -6.394 25.086 56.944 1.00 16.81 ? 82 ASP L CA 1 ATOM 664 C C . ASP A 1 87 ? -6.485 24.845 55.458 1.00 13.29 ? 82 ASP L C 1 ATOM 665 O O . ASP A 1 87 ? -6.923 23.783 55.044 1.00 13.67 ? 82 ASP L O 1 ATOM 666 C CB . ASP A 1 87 ? -7.794 25.200 57.464 1.00 18.97 ? 82 ASP L CB 1 ATOM 667 C CG . ASP A 1 87 ? -7.887 25.332 58.974 1.00 18.42 ? 82 ASP L CG 1 ATOM 668 O OD1 . ASP A 1 87 ? -6.991 24.907 59.718 1.00 13.47 ? 82 ASP L OD1 1 ATOM 669 O OD2 . ASP A 1 87 ? -8.901 25.887 59.387 1.00 16.32 ? 82 ASP L OD2 1 ATOM 670 N N . LEU A 1 88 ? -6.123 25.870 54.680 1.00 12.80 ? 83 LEU L N 1 ATOM 671 C CA . LEU A 1 88 ? -5.968 25.878 53.224 1.00 13.87 ? 83 LEU L CA 1 ATOM 672 C C . LEU A 1 88 ? -5.233 24.612 52.703 1.00 15.58 ? 83 LEU L C 1 ATOM 673 O O . LEU A 1 88 ? -4.085 24.274 53.049 1.00 14.67 ? 83 LEU L O 1 ATOM 674 C CB . LEU A 1 88 ? -5.200 27.149 52.961 1.00 16.11 ? 83 LEU L CB 1 ATOM 675 C CG . LEU A 1 88 ? -5.089 28.010 51.733 1.00 14.60 ? 83 LEU L CG 1 ATOM 676 C CD1 . LEU A 1 88 ? -4.129 29.135 52.111 1.00 20.70 ? 83 LEU L CD1 1 ATOM 677 C CD2 . LEU A 1 88 ? -4.513 27.296 50.555 1.00 17.55 ? 83 LEU L CD2 1 ATOM 678 N N . GLY A 1 89 ? -5.896 23.916 51.798 1.00 15.64 ? 84 GLY L N 1 ATOM 679 C CA . GLY A 1 89 ? -5.390 22.686 51.232 1.00 13.29 ? 84 GLY L CA 1 ATOM 680 C C . GLY A 1 89 ? -6.545 21.991 50.524 1.00 14.79 ? 84 GLY L C 1 ATOM 681 O O . GLY A 1 89 ? -7.637 22.553 50.303 1.00 18.82 ? 84 GLY L O 1 ATOM 682 N N . VAL A 1 90 ? -6.319 20.762 50.110 1.00 6.37 ? 85 VAL L N 1 ATOM 683 C CA . VAL A 1 90 ? -7.367 20.051 49.435 1.00 8.27 ? 85 VAL L CA 1 ATOM 684 C C . VAL A 1 90 ? -7.683 18.861 50.313 1.00 10.97 ? 85 VAL L C 1 ATOM 685 O O . VAL A 1 90 ? -6.795 18.139 50.781 1.00 13.22 ? 85 VAL L O 1 ATOM 686 C CB . VAL A 1 90 ? -6.849 19.634 48.073 1.00 11.79 ? 85 VAL L CB 1 ATOM 687 C CG1 . VAL A 1 90 ? -7.911 18.906 47.314 1.00 13.60 ? 85 VAL L CG1 1 ATOM 688 C CG2 . VAL A 1 90 ? -6.420 20.848 47.309 1.00 14.03 ? 85 VAL L CG2 1 ATOM 689 N N . TYR A 1 91 ? -8.950 18.656 50.590 1.00 9.50 ? 86 TYR L N 1 ATOM 690 C CA . TYR A 1 91 ? -9.373 17.555 51.410 1.00 6.39 ? 86 TYR L CA 1 ATOM 691 C C . TYR A 1 91 ? -9.796 16.426 50.482 1.00 13.28 ? 86 TYR L C 1 ATOM 692 O O . TYR A 1 91 ? -10.524 16.666 49.503 1.00 11.50 ? 86 TYR L O 1 ATOM 693 C CB . TYR A 1 91 ? -10.514 18.054 52.278 1.00 7.18 ? 86 TYR L CB 1 ATOM 694 C CG . TYR A 1 91 ? -10.021 19.029 53.335 1.00 9.75 ? 86 TYR L CG 1 ATOM 695 C CD1 . TYR A 1 91 ? -9.740 20.352 52.974 1.00 12.25 ? 86 TYR L CD1 1 ATOM 696 C CD2 . TYR A 1 91 ? -9.808 18.577 54.624 1.00 2.00 ? 86 TYR L CD2 1 ATOM 697 C CE1 . TYR A 1 91 ? -9.230 21.238 53.899 1.00 3.97 ? 86 TYR L CE1 1 ATOM 698 C CE2 . TYR A 1 91 ? -9.303 19.455 55.546 1.00 4.40 ? 86 TYR L CE2 1 ATOM 699 C CZ . TYR A 1 91 ? -9.021 20.759 55.172 1.00 8.25 ? 86 TYR L CZ 1 ATOM 700 O OH . TYR A 1 91 ? -8.480 21.608 56.096 1.00 14.42 ? 86 TYR L OH 1 ATOM 701 N N . TYR A 1 92 ? -9.333 15.201 50.705 1.00 14.03 ? 87 TYR L N 1 ATOM 702 C CA . TYR A 1 92 ? -9.779 14.075 49.924 1.00 10.37 ? 87 TYR L CA 1 ATOM 703 C C . TYR A 1 92 ? -10.363 13.107 50.927 1.00 11.05 ? 87 TYR L C 1 ATOM 704 O O . TYR A 1 92 ? -9.700 12.852 51.923 1.00 14.61 ? 87 TYR L O 1 ATOM 705 C CB . TYR A 1 92 ? -8.657 13.380 49.287 1.00 5.42 ? 87 TYR L CB 1 ATOM 706 C CG . TYR A 1 92 ? -7.805 14.179 48.357 1.00 7.99 ? 87 TYR L CG 1 ATOM 707 C CD1 . TYR A 1 92 ? -8.258 14.400 47.079 1.00 7.52 ? 87 TYR L CD1 1 ATOM 708 C CD2 . TYR A 1 92 ? -6.554 14.592 48.755 1.00 9.76 ? 87 TYR L CD2 1 ATOM 709 C CE1 . TYR A 1 92 ? -7.451 15.026 46.161 1.00 2.00 ? 87 TYR L CE1 1 ATOM 710 C CE2 . TYR A 1 92 ? -5.746 15.212 47.832 1.00 6.01 ? 87 TYR L CE2 1 ATOM 711 C CZ . TYR A 1 92 ? -6.206 15.418 46.547 1.00 2.00 ? 87 TYR L CZ 1 ATOM 712 O OH . TYR A 1 92 ? -5.390 15.991 45.605 1.00 2.00 ? 87 TYR L OH 1 ATOM 713 N N . CYS A 1 93 ? -11.584 12.618 50.786 1.00 13.36 ? 88 CYS L N 1 ATOM 714 C CA . CYS A 1 93 ? -12.131 11.563 51.631 1.00 13.94 ? 88 CYS L CA 1 ATOM 715 C C . CYS A 1 93 ? -11.644 10.301 50.962 1.00 18.47 ? 88 CYS L C 1 ATOM 716 O O . CYS A 1 93 ? -11.362 10.337 49.744 1.00 20.79 ? 88 CYS L O 1 ATOM 717 C CB . CYS A 1 93 ? -13.648 11.484 51.618 1.00 17.51 ? 88 CYS L CB 1 ATOM 718 S SG . CYS A 1 93 ? -14.403 11.547 49.962 1.00 24.49 ? 88 CYS L SG 1 ATOM 719 N N . PHE A 1 94 ? -11.629 9.177 51.689 1.00 15.30 ? 89 PHE L N 1 ATOM 720 C CA . PHE A 1 94 ? -11.090 7.934 51.145 1.00 15.80 ? 89 PHE L CA 1 ATOM 721 C C . PHE A 1 94 ? -11.871 6.817 51.708 1.00 16.02 ? 89 PHE L C 1 ATOM 722 O O . PHE A 1 94 ? -12.433 7.002 52.775 1.00 18.03 ? 89 PHE L O 1 ATOM 723 C CB . PHE A 1 94 ? -9.632 7.776 51.558 1.00 19.53 ? 89 PHE L CB 1 ATOM 724 C CG . PHE A 1 94 ? -8.956 6.435 51.406 1.00 12.46 ? 89 PHE L CG 1 ATOM 725 C CD1 . PHE A 1 94 ? -8.490 6.038 50.178 1.00 13.64 ? 89 PHE L CD1 1 ATOM 726 C CD2 . PHE A 1 94 ? -8.829 5.642 52.520 1.00 9.70 ? 89 PHE L CD2 1 ATOM 727 C CE1 . PHE A 1 94 ? -7.879 4.810 50.075 1.00 16.05 ? 89 PHE L CE1 1 ATOM 728 C CE2 . PHE A 1 94 ? -8.221 4.419 52.405 1.00 11.70 ? 89 PHE L CE2 1 ATOM 729 C CZ . PHE A 1 94 ? -7.744 4.000 51.182 1.00 11.82 ? 89 PHE L CZ 1 ATOM 730 N N . GLN A 1 95 ? -11.840 5.673 51.045 1.00 24.95 ? 90 GLN L N 1 ATOM 731 C CA . GLN A 1 95 ? -12.491 4.468 51.544 1.00 26.35 ? 90 GLN L CA 1 ATOM 732 C C . GLN A 1 95 ? -11.528 3.294 51.443 1.00 20.48 ? 90 GLN L C 1 ATOM 733 O O . GLN A 1 95 ? -10.885 3.046 50.417 1.00 12.49 ? 90 GLN L O 1 ATOM 734 C CB . GLN A 1 95 ? -13.793 4.188 50.736 1.00 25.59 ? 90 GLN L CB 1 ATOM 735 C CG . GLN A 1 95 ? -13.683 3.860 49.235 1.00 29.09 ? 90 GLN L CG 1 ATOM 736 C CD . GLN A 1 95 ? -13.420 2.388 49.030 1.00 30.10 ? 90 GLN L CD 1 ATOM 737 O OE1 . GLN A 1 95 ? -13.723 1.603 49.939 1.00 40.02 ? 90 GLN L OE1 1 ATOM 738 N NE2 . GLN A 1 95 ? -12.821 1.954 47.941 1.00 23.14 ? 90 GLN L NE2 1 ATOM 739 N N . GLY A 1 96 ? -11.411 2.604 52.548 1.00 22.03 ? 91 GLY L N 1 ATOM 740 C CA . GLY A 1 96 ? -10.573 1.448 52.581 1.00 28.33 ? 91 GLY L CA 1 ATOM 741 C C . GLY A 1 96 ? -11.402 0.207 52.720 1.00 33.01 ? 91 GLY L C 1 ATOM 742 O O . GLY A 1 96 ? -10.867 -0.881 52.526 1.00 42.86 ? 91 GLY L O 1 ATOM 743 N N . SER A 1 97 ? -12.699 0.291 53.032 1.00 31.43 ? 92 SER L N 1 ATOM 744 C CA . SER A 1 97 ? -13.461 -0.932 53.239 1.00 32.36 ? 92 SER L CA 1 ATOM 745 C C . SER A 1 97 ? -13.695 -1.778 51.975 1.00 30.10 ? 92 SER L C 1 ATOM 746 O O . SER A 1 97 ? -14.149 -2.914 52.095 1.00 33.92 ? 92 SER L O 1 ATOM 747 C CB . SER A 1 97 ? -14.801 -0.572 53.902 1.00 32.21 ? 92 SER L CB 1 ATOM 748 O OG . SER A 1 97 ? -15.756 0.103 53.084 1.00 33.99 ? 92 SER L OG 1 ATOM 749 N N . HIS A 1 98 ? -13.453 -1.361 50.727 1.00 26.36 ? 93 HIS L N 1 ATOM 750 C CA . HIS A 1 98 ? -13.681 -2.215 49.563 1.00 24.62 ? 93 HIS L CA 1 ATOM 751 C C . HIS A 1 98 ? -12.588 -2.190 48.490 1.00 28.19 ? 93 HIS L C 1 ATOM 752 O O . HIS A 1 98 ? -12.383 -1.154 47.848 1.00 33.04 ? 93 HIS L O 1 ATOM 753 C CB . HIS A 1 98 ? -15.007 -1.837 48.905 1.00 28.63 ? 93 HIS L CB 1 ATOM 754 C CG . HIS A 1 98 ? -16.235 -2.204 49.734 1.00 36.07 ? 93 HIS L CG 1 ATOM 755 N ND1 . HIS A 1 98 ? -16.593 -3.390 50.240 1.00 35.78 ? 93 HIS L ND1 1 ATOM 756 C CD2 . HIS A 1 98 ? -17.199 -1.289 50.095 1.00 38.83 ? 93 HIS L CD2 1 ATOM 757 C CE1 . HIS A 1 98 ? -17.727 -3.213 50.886 1.00 38.73 ? 93 HIS L CE1 1 ATOM 758 N NE2 . HIS A 1 98 ? -18.081 -1.955 50.792 1.00 37.40 ? 93 HIS L NE2 1 ATOM 759 N N . VAL A 1 99 ? -11.890 -3.320 48.236 1.00 22.70 ? 94 VAL L N 1 ATOM 760 C CA . VAL A 1 99 ? -10.802 -3.411 47.249 1.00 13.06 ? 94 VAL L CA 1 ATOM 761 C C . VAL A 1 99 ? -11.188 -3.116 45.800 1.00 17.76 ? 94 VAL L C 1 ATOM 762 O O . VAL A 1 99 ? -12.129 -3.751 45.321 1.00 23.20 ? 94 VAL L O 1 ATOM 763 C CB . VAL A 1 99 ? -10.183 -4.806 47.288 1.00 3.40 ? 94 VAL L CB 1 ATOM 764 C CG1 . VAL A 1 99 ? -9.041 -4.909 46.290 1.00 6.15 ? 94 VAL L CG1 1 ATOM 765 C CG2 . VAL A 1 99 ? -9.577 -5.079 48.645 1.00 2.00 ? 94 VAL L CG2 1 ATOM 766 N N . PRO A 1 100 ? -10.489 -2.280 45.014 1.00 18.50 ? 95 PRO L N 1 ATOM 767 C CA . PRO A 1 100 ? -9.363 -1.430 45.401 1.00 12.23 ? 95 PRO L CA 1 ATOM 768 C C . PRO A 1 100 ? -9.808 -0.146 46.049 1.00 14.21 ? 95 PRO L C 1 ATOM 769 O O . PRO A 1 100 ? -10.825 0.413 45.613 1.00 16.53 ? 95 PRO L O 1 ATOM 770 C CB . PRO A 1 100 ? -8.629 -1.197 44.130 1.00 11.63 ? 95 PRO L CB 1 ATOM 771 C CG . PRO A 1 100 ? -9.696 -1.164 43.081 1.00 10.89 ? 95 PRO L CG 1 ATOM 772 C CD . PRO A 1 100 ? -10.639 -2.268 43.561 1.00 17.58 ? 95 PRO L CD 1 ATOM 773 N N . PRO A 1 101 ? -9.067 0.337 47.062 1.00 13.73 ? 96 PRO L N 1 ATOM 774 C CA . PRO A 1 101 ? -9.433 1.475 47.894 1.00 7.53 ? 96 PRO L CA 1 ATOM 775 C C . PRO A 1 101 ? -9.583 2.696 47.012 1.00 9.50 ? 96 PRO L C 1 ATOM 776 O O . PRO A 1 101 ? -8.881 2.786 45.999 1.00 3.21 ? 96 PRO L O 1 ATOM 777 C CB . PRO A 1 101 ? -8.307 1.607 48.842 1.00 8.14 ? 96 PRO L CB 1 ATOM 778 C CG . PRO A 1 101 ? -7.539 0.319 48.751 1.00 8.50 ? 96 PRO L CG 1 ATOM 779 C CD . PRO A 1 101 ? -7.656 0.063 47.282 1.00 9.60 ? 96 PRO L CD 1 ATOM 780 N N . THR A 1 102 ? -10.422 3.677 47.316 1.00 16.38 ? 97 THR L N 1 ATOM 781 C CA . THR A 1 102 ? -10.497 4.800 46.412 1.00 16.85 ? 97 THR L CA 1 ATOM 782 C C . THR A 1 102 ? -10.764 6.109 47.111 1.00 17.13 ? 97 THR L C 1 ATOM 783 O O . THR A 1 102 ? -11.283 6.159 48.230 1.00 22.63 ? 97 THR L O 1 ATOM 784 C CB . THR A 1 102 ? -11.555 4.510 45.322 1.00 17.83 ? 97 THR L CB 1 ATOM 785 O OG1 . THR A 1 102 ? -12.303 3.358 45.636 1.00 16.21 ? 97 THR L OG1 1 ATOM 786 C CG2 . THR A 1 102 ? -10.858 4.298 43.993 1.00 19.50 ? 97 THR L CG2 1 ATOM 787 N N . PHE A 1 103 ? -10.267 7.146 46.449 1.00 13.58 ? 98 PHE L N 1 ATOM 788 C CA . PHE A 1 103 ? -10.295 8.488 46.966 1.00 11.91 ? 98 PHE L CA 1 ATOM 789 C C . PHE A 1 103 ? -11.274 9.353 46.192 1.00 14.78 ? 98 PHE L C 1 ATOM 790 O O . PHE A 1 103 ? -11.542 9.165 44.985 1.00 9.72 ? 98 PHE L O 1 ATOM 791 C CB . PHE A 1 103 ? -8.944 9.193 46.840 1.00 6.82 ? 98 PHE L CB 1 ATOM 792 C CG . PHE A 1 103 ? -7.753 8.719 47.640 1.00 2.00 ? 98 PHE L CG 1 ATOM 793 C CD1 . PHE A 1 103 ? -7.058 7.605 47.250 1.00 2.20 ? 98 PHE L CD1 1 ATOM 794 C CD2 . PHE A 1 103 ? -7.350 9.463 48.707 1.00 2.00 ? 98 PHE L CD2 1 ATOM 795 C CE1 . PHE A 1 103 ? -5.943 7.227 47.924 1.00 2.18 ? 98 PHE L CE1 1 ATOM 796 C CE2 . PHE A 1 103 ? -6.239 9.098 49.387 1.00 2.00 ? 98 PHE L CE2 1 ATOM 797 C CZ . PHE A 1 103 ? -5.539 7.981 48.994 1.00 8.84 ? 98 PHE L CZ 1 ATOM 798 N N . GLY A 1 104 ? -11.690 10.363 46.970 1.00 13.44 ? 99 GLY L N 1 ATOM 799 C CA . GLY A 1 104 ? -12.477 11.443 46.442 1.00 9.10 ? 99 GLY L CA 1 ATOM 800 C C . GLY A 1 104 ? -11.642 12.267 45.459 1.00 10.34 ? 99 GLY L C 1 ATOM 801 O O . GLY A 1 104 ? -10.415 12.201 45.347 1.00 16.88 ? 99 GLY L O 1 ATOM 802 N N . GLY A 1 105 ? -12.316 13.042 44.656 1.00 7.81 ? 100 GLY L N 1 ATOM 803 C CA . GLY A 1 105 ? -11.646 13.976 43.790 1.00 14.04 ? 100 GLY L CA 1 ATOM 804 C C . GLY A 1 105 ? -11.104 15.205 44.520 1.00 19.85 ? 100 GLY L C 1 ATOM 805 O O . GLY A 1 105 ? -10.310 15.940 43.924 1.00 29.61 ? 100 GLY L O 1 ATOM 806 N N . GLY A 1 106 ? -11.492 15.537 45.747 1.00 15.53 ? 101 GLY L N 1 ATOM 807 C CA . GLY A 1 106 ? -10.933 16.743 46.351 1.00 15.81 ? 101 GLY L CA 1 ATOM 808 C C . GLY A 1 106 ? -11.907 17.892 46.564 1.00 10.53 ? 101 GLY L C 1 ATOM 809 O O . GLY A 1 106 ? -12.960 17.962 45.937 1.00 13.01 ? 101 GLY L O 1 ATOM 810 N N . THR A 1 107 ? -11.643 18.704 47.583 1.00 4.26 ? 102 THR L N 1 ATOM 811 C CA . THR A 1 107 ? -12.372 19.937 47.808 1.00 11.80 ? 102 THR L CA 1 ATOM 812 C C . THR A 1 107 ? -11.238 20.835 48.246 1.00 15.67 ? 102 THR L C 1 ATOM 813 O O . THR A 1 107 ? -10.433 20.432 49.114 1.00 11.25 ? 102 THR L O 1 ATOM 814 C CB . THR A 1 107 ? -13.374 19.808 48.940 1.00 15.70 ? 102 THR L CB 1 ATOM 815 O OG1 . THR A 1 107 ? -14.225 18.735 48.551 1.00 18.54 ? 102 THR L OG1 1 ATOM 816 C CG2 . THR A 1 107 ? -14.126 21.101 49.241 1.00 10.51 ? 102 THR L CG2 1 ATOM 817 N N . LYS A 1 108 ? -11.159 21.982 47.553 1.00 18.38 ? 103 LYS L N 1 ATOM 818 C CA . LYS A 1 108 ? -10.141 23.001 47.774 1.00 17.46 ? 103 LYS L CA 1 ATOM 819 C C . LYS A 1 108 ? -10.812 23.999 48.691 1.00 13.24 ? 103 LYS L C 1 ATOM 820 O O . LYS A 1 108 ? -11.889 24.502 48.351 1.00 9.64 ? 103 LYS L O 1 ATOM 821 C CB . LYS A 1 108 ? -9.765 23.625 46.429 1.00 23.39 ? 103 LYS L CB 1 ATOM 822 C CG . LYS A 1 108 ? -9.267 25.069 46.348 1.00 31.30 ? 103 LYS L CG 1 ATOM 823 C CD . LYS A 1 108 ? -7.916 25.295 47.024 1.00 43.75 ? 103 LYS L CD 1 ATOM 824 C CE . LYS A 1 108 ? -7.654 26.803 47.246 1.00 46.23 ? 103 LYS L CE 1 ATOM 825 N NZ . LYS A 1 108 ? -6.353 27.016 47.858 1.00 42.33 ? 103 LYS L NZ 1 ATOM 826 N N . LEU A 1 109 ? -10.209 24.231 49.858 1.00 8.09 ? 104 LEU L N 1 ATOM 827 C CA . LEU A 1 109 ? -10.707 25.137 50.874 1.00 8.75 ? 104 LEU L CA 1 ATOM 828 C C . LEU A 1 109 ? -9.993 26.453 50.552 1.00 15.17 ? 104 LEU L C 1 ATOM 829 O O . LEU A 1 109 ? -8.758 26.521 50.518 1.00 19.72 ? 104 LEU L O 1 ATOM 830 C CB . LEU A 1 109 ? -10.315 24.479 52.180 1.00 7.94 ? 104 LEU L CB 1 ATOM 831 C CG . LEU A 1 109 ? -10.463 24.852 53.654 1.00 8.83 ? 104 LEU L CG 1 ATOM 832 C CD1 . LEU A 1 109 ? -9.804 26.201 53.904 1.00 8.37 ? 104 LEU L CD1 1 ATOM 833 C CD2 . LEU A 1 109 ? -11.908 24.721 54.049 1.00 2.00 ? 104 LEU L CD2 1 ATOM 834 N N . GLU A 1 110 ? -10.762 27.502 50.273 1.00 15.25 ? 105 GLU L N 1 ATOM 835 C CA . GLU A 1 110 ? -10.222 28.803 49.962 1.00 12.08 ? 105 GLU L CA 1 ATOM 836 C C . GLU A 1 110 ? -10.556 29.715 51.132 1.00 11.17 ? 105 GLU L C 1 ATOM 837 O O . GLU A 1 110 ? -11.709 29.809 51.570 1.00 9.69 ? 105 GLU L O 1 ATOM 838 C CB . GLU A 1 110 ? -10.869 29.288 48.718 1.00 17.26 ? 105 GLU L CB 1 ATOM 839 C CG . GLU A 1 110 ? -10.575 30.723 48.269 1.00 24.98 ? 105 GLU L CG 1 ATOM 840 C CD . GLU A 1 110 ? -11.304 31.103 46.982 1.00 32.93 ? 105 GLU L CD 1 ATOM 841 O OE1 . GLU A 1 110 ? -12.300 30.460 46.642 1.00 40.63 ? 105 GLU L OE1 1 ATOM 842 O OE2 . GLU A 1 110 ? -10.889 32.045 46.302 1.00 36.44 ? 105 GLU L OE2 1 ATOM 843 N N . ILE A 1 111 ? -9.538 30.359 51.679 1.00 7.91 ? 106 ILE L N 1 ATOM 844 C CA . ILE A 1 111 ? -9.712 31.277 52.781 1.00 12.95 ? 106 ILE L CA 1 ATOM 845 C C . ILE A 1 111 ? -10.248 32.537 52.157 1.00 12.97 ? 106 ILE L C 1 ATOM 846 O O . ILE A 1 111 ? -9.530 33.045 51.292 1.00 16.78 ? 106 ILE L O 1 ATOM 847 C CB . ILE A 1 111 ? -8.360 31.592 53.465 1.00 14.82 ? 106 ILE L CB 1 ATOM 848 C CG1 . ILE A 1 111 ? -7.754 30.331 54.056 1.00 15.00 ? 106 ILE L CG1 1 ATOM 849 C CG2 . ILE A 1 111 ? -8.568 32.669 54.521 1.00 9.81 ? 106 ILE L CG2 1 ATOM 850 C CD1 . ILE A 1 111 ? -8.607 29.514 55.036 1.00 10.94 ? 106 ILE L CD1 1 ATOM 851 N N . LYS A 1 112 ? -11.388 33.116 52.518 1.00 11.48 ? 107 LYS L N 1 ATOM 852 C CA . LYS A 1 112 ? -11.725 34.338 51.842 1.00 14.53 ? 107 LYS L CA 1 ATOM 853 C C . LYS A 1 112 ? -11.507 35.551 52.703 1.00 18.16 ? 107 LYS L C 1 ATOM 854 O O . LYS A 1 112 ? -12.101 35.749 53.783 1.00 20.81 ? 107 LYS L O 1 ATOM 855 C CB . LYS A 1 112 ? -13.147 34.314 51.342 1.00 14.29 ? 107 LYS L CB 1 ATOM 856 C CG . LYS A 1 112 ? -14.324 34.255 52.246 1.00 15.44 ? 107 LYS L CG 1 ATOM 857 C CD . LYS A 1 112 ? -15.400 35.131 51.595 1.00 23.21 ? 107 LYS L CD 1 ATOM 858 C CE . LYS A 1 112 ? -15.874 34.534 50.265 1.00 27.49 ? 107 LYS L CE 1 ATOM 859 N NZ . LYS A 1 112 ? -16.977 35.277 49.693 1.00 34.85 ? 107 LYS L NZ 1 ATOM 860 N N . ARG A 1 113 ? -10.432 36.180 52.184 1.00 18.55 ? 108 ARG L N 1 ATOM 861 C CA . ARG A 1 113 ? -9.914 37.452 52.678 1.00 17.66 ? 108 ARG L CA 1 ATOM 862 C C . ARG A 1 113 ? -10.690 38.587 52.057 1.00 17.85 ? 108 ARG L C 1 ATOM 863 O O . ARG A 1 113 ? -11.609 38.302 51.286 1.00 20.39 ? 108 ARG L O 1 ATOM 864 C CB . ARG A 1 113 ? -8.432 37.684 52.348 1.00 14.53 ? 108 ARG L CB 1 ATOM 865 C CG . ARG A 1 113 ? -7.936 37.420 50.948 1.00 12.10 ? 108 ARG L CG 1 ATOM 866 C CD . ARG A 1 113 ? -7.172 38.572 50.389 1.00 12.34 ? 108 ARG L CD 1 ATOM 867 N NE . ARG A 1 113 ? -6.074 39.147 51.129 1.00 10.12 ? 108 ARG L NE 1 ATOM 868 C CZ . ARG A 1 113 ? -6.096 40.463 51.452 1.00 20.34 ? 108 ARG L CZ 1 ATOM 869 N NH1 . ARG A 1 113 ? -7.180 41.254 51.332 1.00 20.02 ? 108 ARG L NH1 1 ATOM 870 N NH2 . ARG A 1 113 ? -5.028 41.011 52.038 1.00 23.58 ? 108 ARG L NH2 1 ATOM 871 N N . ALA A 1 114 ? -10.396 39.850 52.437 1.00 20.54 ? 109 ALA L N 1 ATOM 872 C CA . ALA A 1 114 ? -11.060 41.035 51.870 1.00 16.37 ? 109 ALA L CA 1 ATOM 873 C C . ALA A 1 114 ? -10.609 41.172 50.439 1.00 15.81 ? 109 ALA L C 1 ATOM 874 O O . ALA A 1 114 ? -9.560 40.616 50.099 1.00 17.36 ? 109 ALA L O 1 ATOM 875 C CB . ALA A 1 114 ? -10.632 42.291 52.530 1.00 15.12 ? 109 ALA L CB 1 ATOM 876 N N . ASP A 1 115 ? -11.353 41.888 49.607 1.00 11.16 ? 110 ASP L N 1 ATOM 877 C CA . ASP A 1 115 ? -10.936 42.102 48.226 1.00 11.10 ? 110 ASP L CA 1 ATOM 878 C C . ASP A 1 115 ? -9.579 42.775 48.095 1.00 11.36 ? 110 ASP L C 1 ATOM 879 O O . ASP A 1 115 ? -9.297 43.712 48.850 1.00 10.06 ? 110 ASP L O 1 ATOM 880 C CB . ASP A 1 115 ? -11.928 42.952 47.524 1.00 11.73 ? 110 ASP L CB 1 ATOM 881 C CG . ASP A 1 115 ? -13.233 42.225 47.413 1.00 24.18 ? 110 ASP L CG 1 ATOM 882 O OD1 . ASP A 1 115 ? -13.406 41.525 46.424 1.00 27.58 ? 110 ASP L OD1 1 ATOM 883 O OD2 . ASP A 1 115 ? -14.059 42.353 48.321 1.00 34.25 ? 110 ASP L OD2 1 ATOM 884 N N . ALA A 1 116 ? -8.722 42.329 47.176 1.00 8.92 ? 111 ALA L N 1 ATOM 885 C CA . ALA A 1 116 ? -7.434 42.978 47.007 1.00 13.44 ? 111 ALA L CA 1 ATOM 886 C C . ALA A 1 116 ? -7.269 43.097 45.519 1.00 14.45 ? 111 ALA L C 1 ATOM 887 O O . ALA A 1 116 ? -7.718 42.250 44.739 1.00 20.56 ? 111 ALA L O 1 ATOM 888 C CB . ALA A 1 116 ? -6.278 42.161 47.530 1.00 14.25 ? 111 ALA L CB 1 ATOM 889 N N . ALA A 1 117 ? -6.661 44.188 45.114 1.00 10.59 ? 112 ALA L N 1 ATOM 890 C CA . ALA A 1 117 ? -6.617 44.539 43.725 1.00 6.10 ? 112 ALA L CA 1 ATOM 891 C C . ALA A 1 117 ? -5.213 44.235 43.267 1.00 5.78 ? 112 ALA L C 1 ATOM 892 O O . ALA A 1 117 ? -4.316 44.438 44.092 1.00 3.48 ? 112 ALA L O 1 ATOM 893 C CB . ALA A 1 117 ? -6.940 46.014 43.599 1.00 2.00 ? 112 ALA L CB 1 ATOM 894 N N . PRO A 1 118 ? -5.038 43.708 42.027 1.00 3.47 ? 113 PRO L N 1 ATOM 895 C CA . PRO A 1 118 ? -3.781 43.391 41.399 1.00 2.00 ? 113 PRO L CA 1 ATOM 896 C C . PRO A 1 118 ? -2.866 44.558 41.338 1.00 4.76 ? 113 PRO L C 1 ATOM 897 O O . PRO A 1 118 ? -3.270 45.689 41.114 1.00 14.36 ? 113 PRO L O 1 ATOM 898 C CB . PRO A 1 118 ? -4.095 42.928 40.013 1.00 4.71 ? 113 PRO L CB 1 ATOM 899 C CG . PRO A 1 118 ? -5.368 43.633 39.691 1.00 2.00 ? 113 PRO L CG 1 ATOM 900 C CD . PRO A 1 118 ? -6.085 43.490 41.026 1.00 6.15 ? 113 PRO L CD 1 ATOM 901 N N . THR A 1 119 ? -1.610 44.224 41.402 1.00 8.16 ? 114 THR L N 1 ATOM 902 C CA . THR A 1 119 ? -0.558 45.185 41.279 1.00 10.55 ? 114 THR L CA 1 ATOM 903 C C . THR A 1 119 ? -0.037 44.756 39.934 1.00 11.87 ? 114 THR L C 1 ATOM 904 O O . THR A 1 119 ? 0.560 43.665 39.894 1.00 17.94 ? 114 THR L O 1 ATOM 905 C CB . THR A 1 119 ? 0.429 44.932 42.387 1.00 17.06 ? 114 THR L CB 1 ATOM 906 O OG1 . THR A 1 119 ? -0.218 45.131 43.657 1.00 26.82 ? 114 THR L OG1 1 ATOM 907 C CG2 . THR A 1 119 ? 1.654 45.790 42.144 1.00 18.47 ? 114 THR L CG2 1 ATOM 908 N N . VAL A 1 120 ? -0.268 45.533 38.869 1.00 2.21 ? 115 VAL L N 1 ATOM 909 C CA . VAL A 1 120 ? 0.076 45.082 37.532 1.00 2.00 ? 115 VAL L CA 1 ATOM 910 C C . VAL A 1 120 ? 1.423 45.617 37.063 1.00 3.03 ? 115 VAL L C 1 ATOM 911 O O . VAL A 1 120 ? 1.662 46.790 37.317 1.00 2.21 ? 115 VAL L O 1 ATOM 912 C CB . VAL A 1 120 ? -1.035 45.522 36.614 1.00 7.10 ? 115 VAL L CB 1 ATOM 913 C CG1 . VAL A 1 120 ? -0.863 44.970 35.202 1.00 11.92 ? 115 VAL L CG1 1 ATOM 914 C CG2 . VAL A 1 120 ? -2.333 44.997 37.187 1.00 14.20 ? 115 VAL L CG2 1 ATOM 915 N N . SER A 1 121 ? 2.321 44.845 36.416 1.00 8.53 ? 116 SER L N 1 ATOM 916 C CA . SER A 1 121 ? 3.630 45.279 35.907 1.00 8.55 ? 116 SER L CA 1 ATOM 917 C C . SER A 1 121 ? 3.859 44.631 34.554 1.00 9.40 ? 116 SER L C 1 ATOM 918 O O . SER A 1 121 ? 3.625 43.423 34.444 1.00 12.81 ? 116 SER L O 1 ATOM 919 C CB . SER A 1 121 ? 4.771 44.837 36.787 1.00 7.85 ? 116 SER L CB 1 ATOM 920 O OG . SER A 1 121 ? 4.327 44.375 38.058 1.00 24.78 ? 116 SER L OG 1 ATOM 921 N N . ILE A 1 122 ? 4.365 45.363 33.544 1.00 13.79 ? 117 ILE L N 1 ATOM 922 C CA . ILE A 1 122 ? 4.540 44.864 32.161 1.00 13.06 ? 117 ILE L CA 1 ATOM 923 C C . ILE A 1 122 ? 5.987 44.983 31.746 1.00 11.05 ? 117 ILE L C 1 ATOM 924 O O . ILE A 1 122 ? 6.625 46.015 31.986 1.00 12.03 ? 117 ILE L O 1 ATOM 925 C CB . ILE A 1 122 ? 3.644 45.671 31.133 1.00 11.03 ? 117 ILE L CB 1 ATOM 926 C CG1 . ILE A 1 122 ? 3.853 45.223 29.691 1.00 3.97 ? 117 ILE L CG1 1 ATOM 927 C CG2 . ILE A 1 122 ? 3.962 47.153 31.272 1.00 9.84 ? 117 ILE L CG2 1 ATOM 928 C CD1 . ILE A 1 122 ? 2.832 45.825 28.718 1.00 2.00 ? 117 ILE L CD1 1 ATOM 929 N N . PHE A 1 123 ? 6.485 43.961 31.079 1.00 11.92 ? 118 PHE L N 1 ATOM 930 C CA . PHE A 1 123 ? 7.881 43.897 30.677 1.00 8.19 ? 118 PHE L CA 1 ATOM 931 C C . PHE A 1 123 ? 7.934 43.839 29.165 1.00 7.69 ? 118 PHE L C 1 ATOM 932 O O . PHE A 1 123 ? 7.160 43.085 28.565 1.00 13.32 ? 118 PHE L O 1 ATOM 933 C CB . PHE A 1 123 ? 8.527 42.649 31.316 1.00 5.89 ? 118 PHE L CB 1 ATOM 934 C CG . PHE A 1 123 ? 8.532 42.797 32.826 1.00 6.69 ? 118 PHE L CG 1 ATOM 935 C CD1 . PHE A 1 123 ? 7.399 42.467 33.562 1.00 3.87 ? 118 PHE L CD1 1 ATOM 936 C CD2 . PHE A 1 123 ? 9.634 43.363 33.445 1.00 9.89 ? 118 PHE L CD2 1 ATOM 937 C CE1 . PHE A 1 123 ? 7.371 42.721 34.915 1.00 6.69 ? 118 PHE L CE1 1 ATOM 938 C CE2 . PHE A 1 123 ? 9.591 43.614 34.813 1.00 12.39 ? 118 PHE L CE2 1 ATOM 939 C CZ . PHE A 1 123 ? 8.460 43.296 35.547 1.00 8.38 ? 118 PHE L CZ 1 ATOM 940 N N . PRO A 1 124 ? 8.706 44.717 28.511 1.00 8.40 ? 119 PRO L N 1 ATOM 941 C CA . PRO A 1 124 ? 9.285 44.501 27.176 1.00 5.16 ? 119 PRO L CA 1 ATOM 942 C C . PRO A 1 124 ? 10.102 43.233 26.974 1.00 5.57 ? 119 PRO L C 1 ATOM 943 O O . PRO A 1 124 ? 10.657 42.753 27.960 1.00 8.19 ? 119 PRO L O 1 ATOM 944 C CB . PRO A 1 124 ? 10.084 45.739 26.940 1.00 2.87 ? 119 PRO L CB 1 ATOM 945 C CG . PRO A 1 124 ? 10.192 46.395 28.307 1.00 9.13 ? 119 PRO L CG 1 ATOM 946 C CD . PRO A 1 124 ? 8.856 46.107 28.927 1.00 8.72 ? 119 PRO L CD 1 ATOM 947 N N . PRO A 1 125 ? 10.249 42.612 25.790 1.00 6.21 ? 120 PRO L N 1 ATOM 948 C CA . PRO A 1 125 ? 11.086 41.448 25.603 1.00 5.67 ? 120 PRO L CA 1 ATOM 949 C C . PRO A 1 125 ? 12.558 41.782 25.833 1.00 14.13 ? 120 PRO L C 1 ATOM 950 O O . PRO A 1 125 ? 12.993 42.921 25.618 1.00 19.83 ? 120 PRO L O 1 ATOM 951 C CB . PRO A 1 125 ? 10.753 41.017 24.194 1.00 2.00 ? 120 PRO L CB 1 ATOM 952 C CG . PRO A 1 125 ? 10.498 42.295 23.493 1.00 2.00 ? 120 PRO L CG 1 ATOM 953 C CD . PRO A 1 125 ? 9.630 42.992 24.526 1.00 6.00 ? 120 PRO L CD 1 ATOM 954 N N . SER A 1 126 ? 13.361 40.836 26.323 1.00 18.97 ? 121 SER L N 1 ATOM 955 C CA . SER A 1 126 ? 14.798 41.062 26.468 1.00 19.14 ? 121 SER L CA 1 ATOM 956 C C . SER A 1 126 ? 15.474 41.005 25.101 1.00 19.75 ? 121 SER L C 1 ATOM 957 O O . SER A 1 126 ? 15.101 40.188 24.246 1.00 12.18 ? 121 SER L O 1 ATOM 958 C CB . SER A 1 126 ? 15.412 39.990 27.348 1.00 20.45 ? 121 SER L CB 1 ATOM 959 O OG . SER A 1 126 ? 15.081 38.713 26.791 1.00 31.04 ? 121 SER L OG 1 ATOM 960 N N . SER A 1 127 ? 16.524 41.808 24.944 1.00 22.88 ? 122 SER L N 1 ATOM 961 C CA . SER A 1 127 ? 17.385 41.831 23.767 1.00 24.65 ? 122 SER L CA 1 ATOM 962 C C . SER A 1 127 ? 17.952 40.462 23.510 1.00 23.36 ? 122 SER L C 1 ATOM 963 O O . SER A 1 127 ? 18.089 40.108 22.359 1.00 22.51 ? 122 SER L O 1 ATOM 964 C CB . SER A 1 127 ? 18.575 42.745 23.940 1.00 27.38 ? 122 SER L CB 1 ATOM 965 O OG . SER A 1 127 ? 19.185 42.381 25.180 1.00 38.06 ? 122 SER L OG 1 ATOM 966 N N . GLU A 1 128 ? 18.287 39.709 24.561 1.00 23.11 ? 123 GLU L N 1 ATOM 967 C CA . GLU A 1 128 ? 18.781 38.360 24.400 1.00 20.88 ? 123 GLU L CA 1 ATOM 968 C C . GLU A 1 128 ? 17.709 37.531 23.689 1.00 21.70 ? 123 GLU L C 1 ATOM 969 O O . GLU A 1 128 ? 18.011 36.835 22.700 1.00 24.03 ? 123 GLU L O 1 ATOM 970 C CB . GLU A 1 128 ? 19.074 37.753 25.742 1.00 26.10 ? 123 GLU L CB 1 ATOM 971 C CG . GLU A 1 128 ? 19.930 38.632 26.655 1.00 39.29 ? 123 GLU L CG 1 ATOM 972 C CD . GLU A 1 128 ? 20.587 37.896 27.834 1.00 48.18 ? 123 GLU L CD 1 ATOM 973 O OE1 . GLU A 1 128 ? 21.299 36.904 27.608 1.00 56.05 ? 123 GLU L OE1 1 ATOM 974 O OE2 . GLU A 1 128 ? 20.404 38.329 28.976 1.00 44.32 ? 123 GLU L OE2 1 ATOM 975 N N . GLN A 1 129 ? 16.430 37.661 24.102 1.00 12.40 ? 124 GLN L N 1 ATOM 976 C CA . GLN A 1 129 ? 15.397 36.854 23.465 1.00 15.01 ? 124 GLN L CA 1 ATOM 977 C C . GLN A 1 129 ? 15.196 37.303 22.040 1.00 19.09 ? 124 GLN L C 1 ATOM 978 O O . GLN A 1 129 ? 14.993 36.527 21.102 1.00 21.22 ? 124 GLN L O 1 ATOM 979 C CB . GLN A 1 129 ? 14.049 36.972 24.155 1.00 17.56 ? 124 GLN L CB 1 ATOM 980 C CG . GLN A 1 129 ? 13.134 35.905 23.546 1.00 20.88 ? 124 GLN L CG 1 ATOM 981 C CD . GLN A 1 129 ? 11.718 35.834 24.071 1.00 22.04 ? 124 GLN L CD 1 ATOM 982 O OE1 . GLN A 1 129 ? 11.035 34.823 23.891 1.00 21.19 ? 124 GLN L OE1 1 ATOM 983 N NE2 . GLN A 1 129 ? 11.195 36.884 24.691 1.00 14.52 ? 124 GLN L NE2 1 ATOM 984 N N . LEU A 1 130 ? 15.298 38.615 21.928 1.00 22.40 ? 125 LEU L N 1 ATOM 985 C CA . LEU A 1 130 ? 15.038 39.272 20.691 1.00 22.15 ? 125 LEU L CA 1 ATOM 986 C C . LEU A 1 130 ? 16.121 38.931 19.722 1.00 30.51 ? 125 LEU L C 1 ATOM 987 O O . LEU A 1 130 ? 15.757 38.641 18.583 1.00 30.94 ? 125 LEU L O 1 ATOM 988 C CB . LEU A 1 130 ? 14.952 40.734 20.976 1.00 18.69 ? 125 LEU L CB 1 ATOM 989 C CG . LEU A 1 130 ? 13.913 41.502 20.215 1.00 18.09 ? 125 LEU L CG 1 ATOM 990 C CD1 . LEU A 1 130 ? 12.638 40.719 20.109 1.00 22.75 ? 125 LEU L CD1 1 ATOM 991 C CD2 . LEU A 1 130 ? 13.623 42.789 20.956 1.00 18.43 ? 125 LEU L CD2 1 ATOM 992 N N . THR A 1 131 ? 17.390 38.800 20.138 1.00 38.75 ? 126 THR L N 1 ATOM 993 C CA . THR A 1 131 ? 18.451 38.515 19.187 1.00 47.87 ? 126 THR L CA 1 ATOM 994 C C . THR A 1 131 ? 18.465 37.070 18.749 1.00 51.90 ? 126 THR L C 1 ATOM 995 O O . THR A 1 131 ? 19.190 36.686 17.811 1.00 58.64 ? 126 THR L O 1 ATOM 996 C CB . THR A 1 131 ? 19.851 38.873 19.726 1.00 47.66 ? 126 THR L CB 1 ATOM 997 O OG1 . THR A 1 131 ? 19.908 38.629 21.122 1.00 50.98 ? 126 THR L OG1 1 ATOM 998 C CG2 . THR A 1 131 ? 20.171 40.319 19.385 1.00 49.07 ? 126 THR L CG2 1 ATOM 999 N N . SER A 1 132 ? 17.636 36.256 19.393 1.00 49.00 ? 127 SER L N 1 ATOM 1000 C CA . SER A 1 132 ? 17.447 34.963 18.815 1.00 50.56 ? 127 SER L CA 1 ATOM 1001 C C . SER A 1 132 ? 16.040 34.702 18.306 1.00 45.35 ? 127 SER L C 1 ATOM 1002 O O . SER A 1 132 ? 15.502 33.608 18.408 1.00 46.75 ? 127 SER L O 1 ATOM 1003 C CB . SER A 1 132 ? 17.938 33.966 19.848 1.00 58.59 ? 127 SER L CB 1 ATOM 1004 O OG . SER A 1 132 ? 19.371 33.983 19.700 1.00 66.53 ? 127 SER L OG 1 ATOM 1005 N N . GLY A 1 133 ? 15.454 35.755 17.728 1.00 43.89 ? 128 GLY L N 1 ATOM 1006 C CA . GLY A 1 133 ? 14.230 35.688 16.943 1.00 37.85 ? 128 GLY L CA 1 ATOM 1007 C C . GLY A 1 133 ? 12.886 35.758 17.646 1.00 39.05 ? 128 GLY L C 1 ATOM 1008 O O . GLY A 1 133 ? 11.863 35.832 16.941 1.00 41.62 ? 128 GLY L O 1 ATOM 1009 N N . GLY A 1 134 ? 12.781 35.798 18.974 1.00 39.88 ? 129 GLY L N 1 ATOM 1010 C CA . GLY A 1 134 ? 11.465 35.712 19.587 1.00 35.03 ? 129 GLY L CA 1 ATOM 1011 C C . GLY A 1 134 ? 11.148 36.920 20.419 1.00 28.87 ? 129 GLY L C 1 ATOM 1012 O O . GLY A 1 134 ? 12.020 37.716 20.754 1.00 27.87 ? 129 GLY L O 1 ATOM 1013 N N . ALA A 1 135 ? 9.893 37.076 20.774 1.00 24.71 ? 130 ALA L N 1 ATOM 1014 C CA . ALA A 1 135 ? 9.531 38.160 21.640 1.00 20.10 ? 130 ALA L CA 1 ATOM 1015 C C . ALA A 1 135 ? 8.435 37.691 22.591 1.00 17.07 ? 130 ALA L C 1 ATOM 1016 O O . ALA A 1 135 ? 7.389 37.229 22.137 1.00 14.66 ? 130 ALA L O 1 ATOM 1017 C CB . ALA A 1 135 ? 9.062 39.302 20.773 1.00 17.66 ? 130 ALA L CB 1 ATOM 1018 N N . SER A 1 136 ? 8.634 37.720 23.906 1.00 6.42 ? 131 SER L N 1 ATOM 1019 C CA . SER A 1 136 ? 7.562 37.373 24.814 1.00 8.32 ? 131 SER L CA 1 ATOM 1020 C C . SER A 1 136 ? 7.472 38.641 25.627 1.00 9.20 ? 131 SER L C 1 ATOM 1021 O O . SER A 1 136 ? 8.497 39.107 26.157 1.00 16.92 ? 131 SER L O 1 ATOM 1022 C CB . SER A 1 136 ? 7.887 36.206 25.784 1.00 12.58 ? 131 SER L CB 1 ATOM 1023 O OG . SER A 1 136 ? 8.080 34.921 25.232 1.00 17.26 ? 131 SER L OG 1 ATOM 1024 N N . VAL A 1 137 ? 6.304 39.255 25.687 1.00 2.00 ? 132 VAL L N 1 ATOM 1025 C CA . VAL A 1 137 ? 6.170 40.472 26.466 1.00 4.57 ? 132 VAL L CA 1 ATOM 1026 C C . VAL A 1 137 ? 5.342 39.942 27.621 1.00 2.00 ? 132 VAL L C 1 ATOM 1027 O O . VAL A 1 137 ? 4.387 39.210 27.364 1.00 2.00 ? 132 VAL L O 1 ATOM 1028 C CB . VAL A 1 137 ? 5.523 41.584 25.528 1.00 3.63 ? 132 VAL L CB 1 ATOM 1029 C CG1 . VAL A 1 137 ? 4.729 40.987 24.366 1.00 2.00 ? 132 VAL L CG1 1 ATOM 1030 C CG2 . VAL A 1 137 ? 4.650 42.478 26.377 1.00 2.00 ? 132 VAL L CG2 1 ATOM 1031 N N . VAL A 1 138 ? 5.730 40.159 28.883 1.00 4.89 ? 133 VAL L N 1 ATOM 1032 C CA . VAL A 1 138 ? 5.043 39.491 29.993 1.00 6.14 ? 133 VAL L CA 1 ATOM 1033 C C . VAL A 1 138 ? 4.536 40.480 31.028 1.00 6.27 ? 133 VAL L C 1 ATOM 1034 O O . VAL A 1 138 ? 5.126 41.510 31.375 1.00 6.47 ? 133 VAL L O 1 ATOM 1035 C CB . VAL A 1 138 ? 5.960 38.340 30.697 1.00 2.00 ? 133 VAL L CB 1 ATOM 1036 C CG1 . VAL A 1 138 ? 7.265 38.116 29.938 1.00 2.00 ? 133 VAL L CG1 1 ATOM 1037 C CG2 . VAL A 1 138 ? 6.305 38.683 32.117 1.00 2.00 ? 133 VAL L CG2 1 ATOM 1038 N N . CYS A 1 139 ? 3.350 40.118 31.474 1.00 8.22 ? 134 CYS L N 1 ATOM 1039 C CA . CYS A 1 139 ? 2.590 40.947 32.353 1.00 8.97 ? 134 CYS L CA 1 ATOM 1040 C C . CYS A 1 139 ? 2.349 40.134 33.597 1.00 9.07 ? 134 CYS L C 1 ATOM 1041 O O . CYS A 1 139 ? 1.900 38.978 33.537 1.00 11.26 ? 134 CYS L O 1 ATOM 1042 C CB . CYS A 1 139 ? 1.303 41.303 31.659 1.00 8.18 ? 134 CYS L CB 1 ATOM 1043 S SG . CYS A 1 139 ? 0.588 42.710 32.526 1.00 16.63 ? 134 CYS L SG 1 ATOM 1044 N N . PHE A 1 140 ? 2.711 40.725 34.717 1.00 5.68 ? 135 PHE L N 1 ATOM 1045 C CA . PHE A 1 140 ? 2.543 40.091 36.004 1.00 9.10 ? 135 PHE L CA 1 ATOM 1046 C C . PHE A 1 140 ? 1.402 40.839 36.667 1.00 14.80 ? 135 PHE L C 1 ATOM 1047 O O . PHE A 1 140 ? 1.424 42.075 36.646 1.00 20.99 ? 135 PHE L O 1 ATOM 1048 C CB . PHE A 1 140 ? 3.788 40.249 36.856 1.00 10.75 ? 135 PHE L CB 1 ATOM 1049 C CG . PHE A 1 140 ? 4.984 39.411 36.435 1.00 10.96 ? 135 PHE L CG 1 ATOM 1050 C CD1 . PHE A 1 140 ? 4.861 38.063 36.208 1.00 10.14 ? 135 PHE L CD1 1 ATOM 1051 C CD2 . PHE A 1 140 ? 6.210 40.012 36.281 1.00 10.36 ? 135 PHE L CD2 1 ATOM 1052 C CE1 . PHE A 1 140 ? 5.967 37.338 35.828 1.00 11.54 ? 135 PHE L CE1 1 ATOM 1053 C CE2 . PHE A 1 140 ? 7.307 39.270 35.900 1.00 8.22 ? 135 PHE L CE2 1 ATOM 1054 C CZ . PHE A 1 140 ? 7.189 37.929 35.672 1.00 6.40 ? 135 PHE L CZ 1 ATOM 1055 N N . LEU A 1 141 ? 0.360 40.191 37.192 1.00 13.70 ? 136 LEU L N 1 ATOM 1056 C CA . LEU A 1 141 ? -0.721 40.888 37.873 1.00 10.03 ? 136 LEU L CA 1 ATOM 1057 C C . LEU A 1 141 ? -0.612 40.228 39.225 1.00 9.70 ? 136 LEU L C 1 ATOM 1058 O O . LEU A 1 141 ? -0.911 39.035 39.365 1.00 9.85 ? 136 LEU L O 1 ATOM 1059 C CB . LEU A 1 141 ? -2.065 40.593 37.230 1.00 10.69 ? 136 LEU L CB 1 ATOM 1060 C CG . LEU A 1 141 ? -2.486 41.179 35.864 1.00 12.70 ? 136 LEU L CG 1 ATOM 1061 C CD1 . LEU A 1 141 ? -1.770 40.562 34.683 1.00 12.90 ? 136 LEU L CD1 1 ATOM 1062 C CD2 . LEU A 1 141 ? -3.925 40.809 35.646 1.00 7.06 ? 136 LEU L CD2 1 ATOM 1063 N N . ASN A 1 142 ? -0.047 40.922 40.216 1.00 7.81 ? 137 ASN L N 1 ATOM 1064 C CA . ASN A 1 142 ? 0.234 40.263 41.490 1.00 12.82 ? 137 ASN L CA 1 ATOM 1065 C C . ASN A 1 142 ? -0.633 40.658 42.642 1.00 9.36 ? 137 ASN L C 1 ATOM 1066 O O . ASN A 1 142 ? -1.177 41.757 42.647 1.00 13.38 ? 137 ASN L O 1 ATOM 1067 C CB . ASN A 1 142 ? 1.671 40.492 41.965 1.00 13.51 ? 137 ASN L CB 1 ATOM 1068 C CG . ASN A 1 142 ? 2.750 39.974 41.029 1.00 15.65 ? 137 ASN L CG 1 ATOM 1069 O OD1 . ASN A 1 142 ? 3.931 39.976 41.367 1.00 20.12 ? 137 ASN L OD1 1 ATOM 1070 N ND2 . ASN A 1 142 ? 2.477 39.486 39.831 1.00 12.50 ? 137 ASN L ND2 1 ATOM 1071 N N . ASN A 1 143 ? -0.812 39.718 43.561 1.00 6.72 ? 138 ASN L N 1 ATOM 1072 C CA . ASN A 1 143 ? -1.451 39.969 44.851 1.00 14.73 ? 138 ASN L CA 1 ATOM 1073 C C . ASN A 1 143 ? -2.880 40.483 44.844 1.00 18.11 ? 138 ASN L C 1 ATOM 1074 O O . ASN A 1 143 ? -3.147 41.637 45.204 1.00 21.00 ? 138 ASN L O 1 ATOM 1075 C CB . ASN A 1 143 ? -0.608 40.957 45.661 1.00 17.90 ? 138 ASN L CB 1 ATOM 1076 C CG . ASN A 1 143 ? 0.644 40.456 46.366 1.00 17.33 ? 138 ASN L CG 1 ATOM 1077 O OD1 . ASN A 1 143 ? 1.615 39.936 45.819 1.00 19.29 ? 138 ASN L OD1 1 ATOM 1078 N ND2 . ASN A 1 143 ? 0.703 40.665 47.664 1.00 29.37 ? 138 ASN L ND2 1 ATOM 1079 N N . PHE A 1 144 ? -3.839 39.620 44.501 1.00 13.17 ? 139 PHE L N 1 ATOM 1080 C CA . PHE A 1 144 ? -5.213 40.072 44.433 1.00 10.29 ? 139 PHE L CA 1 ATOM 1081 C C . PHE A 1 144 ? -6.144 39.030 44.965 1.00 12.42 ? 139 PHE L C 1 ATOM 1082 O O . PHE A 1 144 ? -5.720 37.899 45.170 1.00 18.42 ? 139 PHE L O 1 ATOM 1083 C CB . PHE A 1 144 ? -5.603 40.384 43.011 1.00 10.87 ? 139 PHE L CB 1 ATOM 1084 C CG . PHE A 1 144 ? -5.386 39.294 41.954 1.00 16.37 ? 139 PHE L CG 1 ATOM 1085 C CD1 . PHE A 1 144 ? -6.390 38.390 41.653 1.00 15.69 ? 139 PHE L CD1 1 ATOM 1086 C CD2 . PHE A 1 144 ? -4.200 39.240 41.228 1.00 18.76 ? 139 PHE L CD2 1 ATOM 1087 C CE1 . PHE A 1 144 ? -6.205 37.467 40.644 1.00 16.89 ? 139 PHE L CE1 1 ATOM 1088 C CE2 . PHE A 1 144 ? -4.023 38.310 40.216 1.00 17.87 ? 139 PHE L CE2 1 ATOM 1089 C CZ . PHE A 1 144 ? -5.027 37.424 39.924 1.00 18.63 ? 139 PHE L CZ 1 ATOM 1090 N N . TYR A 1 145 ? -7.385 39.405 45.210 1.00 13.42 ? 140 TYR L N 1 ATOM 1091 C CA . TYR A 1 145 ? -8.435 38.516 45.669 1.00 14.73 ? 140 TYR L CA 1 ATOM 1092 C C . TYR A 1 145 ? -9.710 39.200 45.195 1.00 15.79 ? 140 TYR L C 1 ATOM 1093 O O . TYR A 1 145 ? -9.771 40.431 45.266 1.00 22.90 ? 140 TYR L O 1 ATOM 1094 C CB . TYR A 1 145 ? -8.516 38.397 47.199 1.00 11.63 ? 140 TYR L CB 1 ATOM 1095 C CG . TYR A 1 145 ? -9.406 37.239 47.619 1.00 9.45 ? 140 TYR L CG 1 ATOM 1096 C CD1 . TYR A 1 145 ? -10.754 37.426 47.694 1.00 10.83 ? 140 TYR L CD1 1 ATOM 1097 C CD2 . TYR A 1 145 ? -8.897 35.965 47.795 1.00 11.06 ? 140 TYR L CD2 1 ATOM 1098 C CE1 . TYR A 1 145 ? -11.597 36.358 47.913 1.00 12.47 ? 140 TYR L CE1 1 ATOM 1099 C CE2 . TYR A 1 145 ? -9.738 34.892 48.022 1.00 7.77 ? 140 TYR L CE2 1 ATOM 1100 C CZ . TYR A 1 145 ? -11.093 35.103 48.068 1.00 9.32 ? 140 TYR L CZ 1 ATOM 1101 O OH . TYR A 1 145 ? -11.990 34.071 48.216 1.00 15.23 ? 140 TYR L OH 1 ATOM 1102 N N . PRO A 1 146 ? -10.762 38.551 44.701 1.00 12.16 ? 141 PRO L N 1 ATOM 1103 C CA . PRO A 1 146 ? -10.771 37.147 44.329 1.00 15.03 ? 141 PRO L CA 1 ATOM 1104 C C . PRO A 1 146 ? -9.966 36.800 43.108 1.00 17.04 ? 141 PRO L C 1 ATOM 1105 O O . PRO A 1 146 ? -9.517 37.696 42.392 1.00 16.09 ? 141 PRO L O 1 ATOM 1106 C CB . PRO A 1 146 ? -12.235 36.819 44.201 1.00 18.62 ? 141 PRO L CB 1 ATOM 1107 C CG . PRO A 1 146 ? -12.966 38.135 44.017 1.00 12.23 ? 141 PRO L CG 1 ATOM 1108 C CD . PRO A 1 146 ? -12.118 39.066 44.836 1.00 11.09 ? 141 PRO L CD 1 ATOM 1109 N N . LYS A 1 147 ? -9.794 35.484 42.949 1.00 16.29 ? 142 LYS L N 1 ATOM 1110 C CA . LYS A 1 147 ? -8.983 34.910 41.890 1.00 17.62 ? 142 LYS L CA 1 ATOM 1111 C C . LYS A 1 147 ? -9.388 35.294 40.480 1.00 23.03 ? 142 LYS L C 1 ATOM 1112 O O . LYS A 1 147 ? -8.588 35.302 39.546 1.00 31.72 ? 142 LYS L O 1 ATOM 1113 C CB . LYS A 1 147 ? -9.057 33.443 42.105 1.00 17.04 ? 142 LYS L CB 1 ATOM 1114 C CG . LYS A 1 147 ? -8.436 32.536 41.084 1.00 23.78 ? 142 LYS L CG 1 ATOM 1115 C CD . LYS A 1 147 ? -8.769 31.105 41.471 1.00 32.76 ? 142 LYS L CD 1 ATOM 1116 C CE . LYS A 1 147 ? -10.263 30.889 41.778 1.00 38.84 ? 142 LYS L CE 1 ATOM 1117 N NZ . LYS A 1 147 ? -11.115 31.338 40.681 1.00 44.97 ? 142 LYS L NZ 1 ATOM 1118 N N . ASP A 1 148 ? -10.677 35.540 40.318 1.00 26.99 ? 143 ASP L N 1 ATOM 1119 C CA . ASP A 1 148 ? -11.254 35.958 39.055 1.00 30.53 ? 143 ASP L CA 1 ATOM 1120 C C . ASP A 1 148 ? -10.812 37.293 38.491 1.00 31.82 ? 143 ASP L C 1 ATOM 1121 O O . ASP A 1 148 ? -11.025 38.376 39.082 1.00 33.34 ? 143 ASP L O 1 ATOM 1122 C CB . ASP A 1 148 ? -12.729 35.979 39.216 1.00 36.81 ? 143 ASP L CB 1 ATOM 1123 C CG . ASP A 1 148 ? -13.192 34.562 39.303 1.00 43.43 ? 143 ASP L CG 1 ATOM 1124 O OD1 . ASP A 1 148 ? -12.909 33.826 38.359 1.00 52.36 ? 143 ASP L OD1 1 ATOM 1125 O OD2 . ASP A 1 148 ? -13.806 34.210 40.308 1.00 46.25 ? 143 ASP L OD2 1 ATOM 1126 N N . ILE A 1 149 ? -10.263 37.174 37.285 1.00 18.07 ? 144 ILE L N 1 ATOM 1127 C CA . ILE A 1 149 ? -9.681 38.324 36.652 1.00 9.61 ? 144 ILE L CA 1 ATOM 1128 C C . ILE A 1 149 ? -9.621 38.049 35.178 1.00 9.19 ? 144 ILE L C 1 ATOM 1129 O O . ILE A 1 149 ? -9.563 36.874 34.801 1.00 14.37 ? 144 ILE L O 1 ATOM 1130 C CB . ILE A 1 149 ? -8.321 38.530 37.320 1.00 3.15 ? 144 ILE L CB 1 ATOM 1131 C CG1 . ILE A 1 149 ? -7.716 39.774 36.787 1.00 4.33 ? 144 ILE L CG1 1 ATOM 1132 C CG2 . ILE A 1 149 ? -7.449 37.307 37.145 1.00 2.00 ? 144 ILE L CG2 1 ATOM 1133 C CD1 . ILE A 1 149 ? -6.531 40.090 37.694 1.00 13.44 ? 144 ILE L CD1 1 ATOM 1134 N N . ASN A 1 150 ? -9.702 39.094 34.347 1.00 9.13 ? 145 ASN L N 1 ATOM 1135 C CA . ASN A 1 150 ? -9.644 38.924 32.904 1.00 14.26 ? 145 ASN L CA 1 ATOM 1136 C C . ASN A 1 150 ? -8.495 39.779 32.404 1.00 16.81 ? 145 ASN L C 1 ATOM 1137 O O . ASN A 1 150 ? -8.392 40.937 32.833 1.00 21.61 ? 145 ASN L O 1 ATOM 1138 C CB . ASN A 1 150 ? -10.888 39.417 32.208 1.00 23.91 ? 145 ASN L CB 1 ATOM 1139 C CG . ASN A 1 150 ? -12.219 38.747 32.542 1.00 33.64 ? 145 ASN L CG 1 ATOM 1140 O OD1 . ASN A 1 150 ? -12.486 37.604 32.167 1.00 38.66 ? 145 ASN L OD1 1 ATOM 1141 N ND2 . ASN A 1 150 ? -13.156 39.434 33.198 1.00 38.44 ? 145 ASN L ND2 1 ATOM 1142 N N . VAL A 1 151 ? -7.578 39.269 31.579 1.00 8.64 ? 146 VAL L N 1 ATOM 1143 C CA . VAL A 1 151 ? -6.559 40.132 31.020 1.00 5.80 ? 146 VAL L CA 1 ATOM 1144 C C . VAL A 1 151 ? -6.710 40.104 29.513 1.00 11.21 ? 146 VAL L C 1 ATOM 1145 O O . VAL A 1 151 ? -7.112 39.080 28.953 1.00 13.73 ? 146 VAL L O 1 ATOM 1146 C CB . VAL A 1 151 ? -5.196 39.649 31.318 1.00 3.11 ? 146 VAL L CB 1 ATOM 1147 C CG1 . VAL A 1 151 ? -4.152 40.655 30.883 1.00 6.28 ? 146 VAL L CG1 1 ATOM 1148 C CG2 . VAL A 1 151 ? -5.072 39.528 32.778 1.00 8.62 ? 146 VAL L CG2 1 ATOM 1149 N N . LYS A 1 152 ? -6.436 41.193 28.806 1.00 15.79 ? 147 LYS L N 1 ATOM 1150 C CA . LYS A 1 152 ? -6.410 41.159 27.346 1.00 11.75 ? 147 LYS L CA 1 ATOM 1151 C C . LYS A 1 152 ? -5.182 41.951 26.903 1.00 12.53 ? 147 LYS L C 1 ATOM 1152 O O . LYS A 1 152 ? -4.724 42.913 27.553 1.00 11.84 ? 147 LYS L O 1 ATOM 1153 C CB . LYS A 1 152 ? -7.718 41.740 26.740 1.00 2.00 ? 147 LYS L CB 1 ATOM 1154 C CG . LYS A 1 152 ? -8.031 43.190 26.829 1.00 2.00 ? 147 LYS L CG 1 ATOM 1155 C CD . LYS A 1 152 ? -9.520 43.398 26.794 1.00 4.55 ? 147 LYS L CD 1 ATOM 1156 C CE . LYS A 1 152 ? -9.850 44.135 25.523 1.00 9.58 ? 147 LYS L CE 1 ATOM 1157 N NZ . LYS A 1 152 ? -11.180 44.712 25.605 1.00 10.05 ? 147 LYS L NZ 1 ATOM 1158 N N . TRP A 1 153 ? -4.575 41.364 25.878 1.00 7.88 ? 148 TRP L N 1 ATOM 1159 C CA . TRP A 1 153 ? -3.398 41.916 25.281 1.00 7.99 ? 148 TRP L CA 1 ATOM 1160 C C . TRP A 1 153 ? -3.731 42.879 24.142 1.00 11.75 ? 148 TRP L C 1 ATOM 1161 O O . TRP A 1 153 ? -4.382 42.485 23.165 1.00 13.06 ? 148 TRP L O 1 ATOM 1162 C CB . TRP A 1 153 ? -2.568 40.753 24.794 1.00 6.69 ? 148 TRP L CB 1 ATOM 1163 C CG . TRP A 1 153 ? -1.809 40.229 25.977 1.00 5.89 ? 148 TRP L CG 1 ATOM 1164 C CD1 . TRP A 1 153 ? -2.220 39.144 26.686 1.00 5.90 ? 148 TRP L CD1 1 ATOM 1165 C CD2 . TRP A 1 153 ? -0.703 40.808 26.488 1.00 2.06 ? 148 TRP L CD2 1 ATOM 1166 N NE1 . TRP A 1 153 ? -1.370 39.038 27.677 1.00 3.42 ? 148 TRP L NE1 1 ATOM 1167 C CE2 . TRP A 1 153 ? -0.453 40.004 27.578 1.00 3.58 ? 148 TRP L CE2 1 ATOM 1168 C CE3 . TRP A 1 153 ? 0.087 41.881 26.168 1.00 3.13 ? 148 TRP L CE3 1 ATOM 1169 C CZ2 . TRP A 1 153 ? 0.618 40.267 28.387 1.00 5.48 ? 148 TRP L CZ2 1 ATOM 1170 C CZ3 . TRP A 1 153 ? 1.166 42.155 26.979 1.00 2.00 ? 148 TRP L CZ3 1 ATOM 1171 C CH2 . TRP A 1 153 ? 1.424 41.354 28.077 1.00 3.75 ? 148 TRP L CH2 1 ATOM 1172 N N . LYS A 1 154 ? -3.370 44.149 24.174 1.00 11.55 ? 149 LYS L N 1 ATOM 1173 C CA . LYS A 1 154 ? -3.586 44.921 22.978 1.00 6.01 ? 149 LYS L CA 1 ATOM 1174 C C . LYS A 1 154 ? -2.280 45.242 22.299 1.00 4.55 ? 149 LYS L C 1 ATOM 1175 O O . LYS A 1 154 ? -1.326 45.696 22.929 1.00 2.00 ? 149 LYS L O 1 ATOM 1176 C CB . LYS A 1 154 ? -4.309 46.230 23.251 1.00 5.23 ? 149 LYS L CB 1 ATOM 1177 C CG . LYS A 1 154 ? -5.719 46.038 23.795 1.00 7.30 ? 149 LYS L CG 1 ATOM 1178 C CD . LYS A 1 154 ? -6.397 47.374 23.877 1.00 5.37 ? 149 LYS L CD 1 ATOM 1179 C CE . LYS A 1 154 ? -7.691 47.225 24.622 1.00 6.02 ? 149 LYS L CE 1 ATOM 1180 N NZ . LYS A 1 154 ? -8.187 48.566 24.890 1.00 6.58 ? 149 LYS L NZ 1 ATOM 1181 N N . ILE A 1 155 ? -2.150 44.885 21.035 1.00 5.18 ? 150 ILE L N 1 ATOM 1182 C CA . ILE A 1 155 ? -1.036 45.345 20.223 1.00 9.94 ? 150 ILE L CA 1 ATOM 1183 C C . ILE A 1 155 ? -1.549 46.568 19.422 1.00 13.71 ? 150 ILE L C 1 ATOM 1184 O O . ILE A 1 155 ? -2.571 46.425 18.748 1.00 23.00 ? 150 ILE L O 1 ATOM 1185 C CB . ILE A 1 155 ? -0.621 44.201 19.295 1.00 7.32 ? 150 ILE L CB 1 ATOM 1186 C CG1 . ILE A 1 155 ? -0.202 42.977 20.058 1.00 2.00 ? 150 ILE L CG1 1 ATOM 1187 C CG2 . ILE A 1 155 ? 0.515 44.688 18.431 1.00 5.61 ? 150 ILE L CG2 1 ATOM 1188 C CD1 . ILE A 1 155 ? -0.027 41.923 18.974 1.00 2.00 ? 150 ILE L CD1 1 ATOM 1189 N N . ASP A 1 156 ? -0.991 47.800 19.441 1.00 11.50 ? 151 ASP L N 1 ATOM 1190 C CA . ASP A 1 156 ? -1.423 48.980 18.644 1.00 6.94 ? 151 ASP L CA 1 ATOM 1191 C C . ASP A 1 156 ? -2.867 49.335 18.843 1.00 11.63 ? 151 ASP L C 1 ATOM 1192 O O . ASP A 1 156 ? -3.613 49.723 17.940 1.00 15.34 ? 151 ASP L O 1 ATOM 1193 C CB . ASP A 1 156 ? -1.259 48.792 17.144 1.00 9.69 ? 151 ASP L CB 1 ATOM 1194 C CG . ASP A 1 156 ? 0.119 49.083 16.545 1.00 18.01 ? 151 ASP L CG 1 ATOM 1195 O OD1 . ASP A 1 156 ? 0.942 49.704 17.219 1.00 16.84 ? 151 ASP L OD1 1 ATOM 1196 O OD2 . ASP A 1 156 ? 0.364 48.711 15.386 1.00 18.57 ? 151 ASP L OD2 1 ATOM 1197 N N . GLY A 1 157 ? -3.254 49.002 20.070 1.00 13.34 ? 152 GLY L N 1 ATOM 1198 C CA . GLY A 1 157 ? -4.587 49.160 20.600 1.00 11.16 ? 152 GLY L CA 1 ATOM 1199 C C . GLY A 1 157 ? -5.644 48.312 19.914 1.00 15.38 ? 152 GLY L C 1 ATOM 1200 O O . GLY A 1 157 ? -6.733 48.050 20.442 1.00 12.46 ? 152 GLY L O 1 ATOM 1201 N N . SER A 1 158 ? -5.296 47.836 18.739 1.00 19.71 ? 153 SER L N 1 ATOM 1202 C CA . SER A 1 158 ? -6.321 47.363 17.883 1.00 32.73 ? 153 SER L CA 1 ATOM 1203 C C . SER A 1 158 ? -6.366 45.965 18.270 1.00 31.17 ? 153 SER L C 1 ATOM 1204 O O . SER A 1 158 ? -7.306 45.472 18.882 1.00 35.65 ? 153 SER L O 1 ATOM 1205 C CB . SER A 1 158 ? -5.930 47.539 16.422 1.00 44.37 ? 153 SER L CB 1 ATOM 1206 O OG . SER A 1 158 ? -7.047 47.161 15.615 1.00 58.82 ? 153 SER L OG 1 ATOM 1207 N N . GLU A 1 159 ? -5.198 45.420 17.986 1.00 40.68 ? 154 GLU L N 1 ATOM 1208 C CA . GLU A 1 159 ? -5.033 44.032 18.212 1.00 44.61 ? 154 GLU L CA 1 ATOM 1209 C C . GLU A 1 159 ? -5.218 43.935 19.702 1.00 37.27 ? 154 GLU L C 1 ATOM 1210 O O . GLU A 1 159 ? -4.627 44.664 20.478 1.00 27.06 ? 154 GLU L O 1 ATOM 1211 C CB . GLU A 1 159 ? -3.623 43.492 17.845 1.00 50.19 ? 154 GLU L CB 1 ATOM 1212 C CG . GLU A 1 159 ? -3.186 43.355 16.377 1.00 55.61 ? 154 GLU L CG 1 ATOM 1213 C CD . GLU A 1 159 ? -2.534 44.560 15.686 1.00 60.39 ? 154 GLU L CD 1 ATOM 1214 O OE1 . GLU A 1 159 ? -2.437 45.665 16.225 1.00 61.30 ? 154 GLU L OE1 1 ATOM 1215 O OE2 . GLU A 1 159 ? -2.107 44.378 14.552 1.00 65.41 ? 154 GLU L OE2 1 ATOM 1216 N N . ARG A 1 160 ? -6.385 43.363 19.914 1.00 24.86 ? 155 ARG L N 1 ATOM 1217 C CA . ARG A 1 160 ? -6.510 42.618 21.110 1.00 21.07 ? 155 ARG L CA 1 ATOM 1218 C C . ARG A 1 160 ? -5.928 41.375 20.415 1.00 21.25 ? 155 ARG L C 1 ATOM 1219 O O . ARG A 1 160 ? -6.349 41.026 19.297 1.00 25.04 ? 155 ARG L O 1 ATOM 1220 C CB . ARG A 1 160 ? -7.938 42.439 21.484 1.00 16.40 ? 155 ARG L CB 1 ATOM 1221 C CG . ARG A 1 160 ? -8.468 43.762 21.873 1.00 15.88 ? 155 ARG L CG 1 ATOM 1222 C CD . ARG A 1 160 ? -9.489 44.069 20.863 1.00 19.82 ? 155 ARG L CD 1 ATOM 1223 N NE . ARG A 1 160 ? -9.734 45.480 20.840 1.00 24.36 ? 155 ARG L NE 1 ATOM 1224 C CZ . ARG A 1 160 ? -10.279 46.104 21.875 1.00 33.51 ? 155 ARG L CZ 1 ATOM 1225 N NH1 . ARG A 1 160 ? -10.662 45.443 22.964 1.00 29.12 ? 155 ARG L NH1 1 ATOM 1226 N NH2 . ARG A 1 160 ? -10.469 47.426 21.795 1.00 44.61 ? 155 ARG L NH2 1 ATOM 1227 N N . GLN A 1 161 ? -4.834 40.784 20.879 1.00 18.79 ? 156 GLN L N 1 ATOM 1228 C CA . GLN A 1 161 ? -4.378 39.590 20.223 1.00 24.56 ? 156 GLN L CA 1 ATOM 1229 C C . GLN A 1 161 ? -4.625 38.303 21.026 1.00 29.56 ? 156 GLN L C 1 ATOM 1230 O O . GLN A 1 161 ? -4.814 38.314 22.255 1.00 24.83 ? 156 GLN L O 1 ATOM 1231 C CB . GLN A 1 161 ? -2.903 39.749 19.918 1.00 26.65 ? 156 GLN L CB 1 ATOM 1232 C CG . GLN A 1 161 ? -2.765 38.944 18.657 1.00 37.47 ? 156 GLN L CG 1 ATOM 1233 C CD . GLN A 1 161 ? -1.364 38.703 18.173 1.00 46.13 ? 156 GLN L CD 1 ATOM 1234 O OE1 . GLN A 1 161 ? -0.924 39.305 17.193 1.00 51.51 ? 156 GLN L OE1 1 ATOM 1235 N NE2 . GLN A 1 161 ? -0.647 37.782 18.807 1.00 47.61 ? 156 GLN L NE2 1 ATOM 1236 N N . ASN A 1 162 ? -4.683 37.181 20.286 1.00 36.24 ? 157 ASN L N 1 ATOM 1237 C CA . ASN A 1 162 ? -4.591 35.871 20.907 1.00 32.02 ? 157 ASN L CA 1 ATOM 1238 C C . ASN A 1 162 ? -3.525 34.853 20.420 1.00 24.00 ? 157 ASN L C 1 ATOM 1239 O O . ASN A 1 162 ? -3.665 34.309 19.328 1.00 19.48 ? 157 ASN L O 1 ATOM 1240 C CB . ASN A 1 162 ? -5.927 35.247 20.834 1.00 34.02 ? 157 ASN L CB 1 ATOM 1241 C CG . ASN A 1 162 ? -5.954 34.694 22.224 1.00 46.46 ? 157 ASN L CG 1 ATOM 1242 O OD1 . ASN A 1 162 ? -5.129 33.862 22.628 1.00 52.28 ? 157 ASN L OD1 1 ATOM 1243 N ND2 . ASN A 1 162 ? -6.837 35.248 23.038 1.00 54.71 ? 157 ASN L ND2 1 ATOM 1244 N N . GLY A 1 163 ? -2.458 34.684 21.253 1.00 22.53 ? 158 GLY L N 1 ATOM 1245 C CA . GLY A 1 163 ? -1.218 33.840 21.180 1.00 14.13 ? 158 GLY L CA 1 ATOM 1246 C C . GLY A 1 163 ? -0.501 33.821 22.594 1.00 17.38 ? 158 GLY L C 1 ATOM 1247 O O . GLY A 1 163 ? 0.723 33.901 22.773 1.00 19.51 ? 158 GLY L O 1 ATOM 1248 N N . VAL A 1 164 ? -1.247 33.659 23.694 1.00 13.25 ? 159 VAL L N 1 ATOM 1249 C CA . VAL A 1 164 ? -0.835 34.033 25.037 1.00 7.34 ? 159 VAL L CA 1 ATOM 1250 C C . VAL A 1 164 ? -1.044 32.954 26.068 1.00 8.80 ? 159 VAL L C 1 ATOM 1251 O O . VAL A 1 164 ? -2.098 32.330 26.057 1.00 12.92 ? 159 VAL L O 1 ATOM 1252 C CB . VAL A 1 164 ? -1.633 35.357 25.440 1.00 7.94 ? 159 VAL L CB 1 ATOM 1253 C CG1 . VAL A 1 164 ? -3.027 35.406 24.816 1.00 2.00 ? 159 VAL L CG1 1 ATOM 1254 C CG2 . VAL A 1 164 ? -1.980 35.381 26.920 1.00 6.13 ? 159 VAL L CG2 1 ATOM 1255 N N . LEU A 1 165 ? -0.116 32.864 27.021 1.00 7.46 ? 160 LEU L N 1 ATOM 1256 C CA . LEU A 1 165 ? -0.126 31.879 28.092 1.00 6.50 ? 160 LEU L CA 1 ATOM 1257 C C . LEU A 1 165 ? -0.454 32.528 29.413 1.00 7.84 ? 160 LEU L C 1 ATOM 1258 O O . LEU A 1 165 ? 0.043 33.629 29.701 1.00 9.26 ? 160 LEU L O 1 ATOM 1259 C CB . LEU A 1 165 ? 1.244 31.222 28.220 1.00 13.52 ? 160 LEU L CB 1 ATOM 1260 C CG . LEU A 1 165 ? 1.641 29.917 27.532 1.00 16.05 ? 160 LEU L CG 1 ATOM 1261 C CD1 . LEU A 1 165 ? 0.961 29.661 26.185 1.00 19.90 ? 160 LEU L CD1 1 ATOM 1262 C CD2 . LEU A 1 165 ? 3.141 30.023 27.393 1.00 18.96 ? 160 LEU L CD2 1 ATOM 1263 N N . ASN A 1 166 ? -1.256 31.906 30.259 1.00 3.26 ? 161 ASN L N 1 ATOM 1264 C CA . ASN A 1 166 ? -1.552 32.521 31.537 1.00 9.75 ? 161 ASN L CA 1 ATOM 1265 C C . ASN A 1 166 ? -1.228 31.523 32.618 1.00 13.79 ? 161 ASN L C 1 ATOM 1266 O O . ASN A 1 166 ? -1.200 30.318 32.322 1.00 18.18 ? 161 ASN L O 1 ATOM 1267 C CB . ASN A 1 166 ? -3.010 32.884 31.694 1.00 8.80 ? 161 ASN L CB 1 ATOM 1268 C CG . ASN A 1 166 ? -3.514 34.031 30.834 1.00 15.80 ? 161 ASN L CG 1 ATOM 1269 O OD1 . ASN A 1 166 ? -4.717 34.292 30.799 1.00 22.42 ? 161 ASN L OD1 1 ATOM 1270 N ND2 . ASN A 1 166 ? -2.719 34.772 30.083 1.00 9.09 ? 161 ASN L ND2 1 ATOM 1271 N N . SER A 1 167 ? -0.977 31.996 33.843 1.00 10.31 ? 162 SER L N 1 ATOM 1272 C CA . SER A 1 167 ? -0.698 31.111 34.942 1.00 8.87 ? 162 SER L CA 1 ATOM 1273 C C . SER A 1 167 ? -1.004 31.769 36.277 1.00 10.65 ? 162 SER L C 1 ATOM 1274 O O . SER A 1 167 ? -0.645 32.916 36.523 1.00 11.72 ? 162 SER L O 1 ATOM 1275 C CB . SER A 1 167 ? 0.757 30.685 34.881 1.00 4.48 ? 162 SER L CB 1 ATOM 1276 O OG . SER A 1 167 ? 1.135 29.718 35.862 1.00 9.81 ? 162 SER L OG 1 ATOM 1277 N N . TRP A 1 168 ? -1.751 31.038 37.101 1.00 11.37 ? 163 TRP L N 1 ATOM 1278 C CA . TRP A 1 168 ? -2.079 31.484 38.423 1.00 14.32 ? 163 TRP L CA 1 ATOM 1279 C C . TRP A 1 168 ? -1.355 30.669 39.480 1.00 12.16 ? 163 TRP L C 1 ATOM 1280 O O . TRP A 1 168 ? -0.920 29.547 39.276 1.00 14.93 ? 163 TRP L O 1 ATOM 1281 C CB . TRP A 1 168 ? -3.565 31.379 38.704 1.00 16.66 ? 163 TRP L CB 1 ATOM 1282 C CG . TRP A 1 168 ? -4.501 32.330 37.946 1.00 24.60 ? 163 TRP L CG 1 ATOM 1283 C CD1 . TRP A 1 168 ? -5.086 33.484 38.474 1.00 23.48 ? 163 TRP L CD1 1 ATOM 1284 C CD2 . TRP A 1 168 ? -4.924 32.072 36.683 1.00 26.27 ? 163 TRP L CD2 1 ATOM 1285 N NE1 . TRP A 1 168 ? -5.892 33.941 37.537 1.00 20.33 ? 163 TRP L NE1 1 ATOM 1286 C CE2 . TRP A 1 168 ? -5.820 33.122 36.455 1.00 28.75 ? 163 TRP L CE2 1 ATOM 1287 C CE3 . TRP A 1 168 ? -4.629 31.065 35.781 1.00 28.03 ? 163 TRP L CE3 1 ATOM 1288 C CZ2 . TRP A 1 168 ? -6.453 33.143 35.231 1.00 36.43 ? 163 TRP L CZ2 1 ATOM 1289 C CZ3 . TRP A 1 168 ? -5.267 31.096 34.566 1.00 34.05 ? 163 TRP L CZ3 1 ATOM 1290 C CH2 . TRP A 1 168 ? -6.166 32.128 34.307 1.00 39.32 ? 163 TRP L CH2 1 ATOM 1291 N N . THR A 1 169 ? -1.131 31.232 40.640 1.00 13.04 ? 164 THR L N 1 ATOM 1292 C CA . THR A 1 169 ? -0.572 30.458 41.697 1.00 13.40 ? 164 THR L CA 1 ATOM 1293 C C . THR A 1 169 ? -1.780 29.992 42.489 1.00 14.46 ? 164 THR L C 1 ATOM 1294 O O . THR A 1 169 ? -2.947 30.316 42.225 1.00 18.15 ? 164 THR L O 1 ATOM 1295 C CB . THR A 1 169 ? 0.379 31.352 42.502 1.00 15.67 ? 164 THR L CB 1 ATOM 1296 O OG1 . THR A 1 169 ? -0.339 32.442 43.058 1.00 21.27 ? 164 THR L OG1 1 ATOM 1297 C CG2 . THR A 1 169 ? 1.491 31.856 41.596 1.00 12.26 ? 164 THR L CG2 1 ATOM 1298 N N . ASP A 1 170 ? -1.491 29.170 43.483 1.00 17.30 ? 165 ASP L N 1 ATOM 1299 C CA . ASP A 1 170 ? -2.513 28.725 44.402 1.00 21.95 ? 165 ASP L CA 1 ATOM 1300 C C . ASP A 1 170 ? -2.655 29.922 45.311 1.00 20.96 ? 165 ASP L C 1 ATOM 1301 O O . ASP A 1 170 ? -1.883 30.897 45.202 1.00 23.64 ? 165 ASP L O 1 ATOM 1302 C CB . ASP A 1 170 ? -2.061 27.549 45.244 1.00 31.36 ? 165 ASP L CB 1 ATOM 1303 C CG . ASP A 1 170 ? -1.448 26.346 44.527 1.00 39.12 ? 165 ASP L CG 1 ATOM 1304 O OD1 . ASP A 1 170 ? -1.900 26.017 43.421 1.00 42.00 ? 165 ASP L OD1 1 ATOM 1305 O OD2 . ASP A 1 170 ? -0.519 25.740 45.099 1.00 43.68 ? 165 ASP L OD2 1 ATOM 1306 N N . GLN A 1 171 ? -3.611 29.834 46.228 1.00 15.63 ? 166 GLN L N 1 ATOM 1307 C CA . GLN A 1 171 ? -3.820 30.922 47.148 1.00 13.21 ? 166 GLN L CA 1 ATOM 1308 C C . GLN A 1 171 ? -2.594 30.979 48.046 1.00 13.94 ? 166 GLN L C 1 ATOM 1309 O O . GLN A 1 171 ? -2.164 29.926 48.536 1.00 16.26 ? 166 GLN L O 1 ATOM 1310 C CB . GLN A 1 171 ? -5.061 30.617 47.888 1.00 11.64 ? 166 GLN L CB 1 ATOM 1311 C CG . GLN A 1 171 ? -5.454 31.792 48.690 1.00 8.99 ? 166 GLN L CG 1 ATOM 1312 C CD . GLN A 1 171 ? -6.799 31.559 49.324 1.00 16.77 ? 166 GLN L CD 1 ATOM 1313 O OE1 . GLN A 1 171 ? -7.165 30.447 49.717 1.00 24.30 ? 166 GLN L OE1 1 ATOM 1314 N NE2 . GLN A 1 171 ? -7.559 32.628 49.468 1.00 15.89 ? 166 GLN L NE2 1 ATOM 1315 N N . ASP A 1 172 ? -1.982 32.156 48.208 1.00 11.67 ? 167 ASP L N 1 ATOM 1316 C CA . ASP A 1 172 ? -0.741 32.260 48.950 1.00 21.00 ? 167 ASP L CA 1 ATOM 1317 C C . ASP A 1 172 ? -0.932 32.074 50.430 1.00 24.50 ? 167 ASP L C 1 ATOM 1318 O O . ASP A 1 172 ? -1.455 32.964 51.093 1.00 28.17 ? 167 ASP L O 1 ATOM 1319 C CB . ASP A 1 172 ? -0.073 33.624 48.735 1.00 25.19 ? 167 ASP L CB 1 ATOM 1320 C CG . ASP A 1 172 ? 1.312 33.838 49.377 1.00 27.05 ? 167 ASP L CG 1 ATOM 1321 O OD1 . ASP A 1 172 ? 1.409 33.933 50.607 1.00 21.77 ? 167 ASP L OD1 1 ATOM 1322 O OD2 . ASP A 1 172 ? 2.292 33.946 48.630 1.00 28.39 ? 167 ASP L OD2 1 ATOM 1323 N N . SER A 1 173 ? -0.378 31.000 50.962 1.00 30.45 ? 168 SER L N 1 ATOM 1324 C CA . SER A 1 173 ? -0.425 30.656 52.375 1.00 33.05 ? 168 SER L CA 1 ATOM 1325 C C . SER A 1 173 ? -0.257 31.801 53.371 1.00 33.10 ? 168 SER L C 1 ATOM 1326 O O . SER A 1 173 ? -0.947 31.870 54.388 1.00 33.66 ? 168 SER L O 1 ATOM 1327 C CB . SER A 1 173 ? 0.648 29.607 52.625 1.00 35.09 ? 168 SER L CB 1 ATOM 1328 O OG . SER A 1 173 ? 1.921 30.055 52.155 1.00 39.06 ? 168 SER L OG 1 ATOM 1329 N N . LYS A 1 174 ? 0.684 32.705 53.076 1.00 28.19 ? 169 LYS L N 1 ATOM 1330 C CA . LYS A 1 174 ? 0.943 33.787 53.985 1.00 24.21 ? 169 LYS L CA 1 ATOM 1331 C C . LYS A 1 174 ? -0.020 34.962 53.831 1.00 26.11 ? 169 LYS L C 1 ATOM 1332 O O . LYS A 1 174 ? 0.063 35.836 54.687 1.00 33.10 ? 169 LYS L O 1 ATOM 1333 C CB . LYS A 1 174 ? 2.364 34.248 53.801 1.00 26.44 ? 169 LYS L CB 1 ATOM 1334 C CG . LYS A 1 174 ? 2.983 34.507 55.156 1.00 40.05 ? 169 LYS L CG 1 ATOM 1335 C CD . LYS A 1 174 ? 4.302 35.298 55.094 1.00 49.76 ? 169 LYS L CD 1 ATOM 1336 C CE . LYS A 1 174 ? 4.890 35.619 56.493 1.00 53.87 ? 169 LYS L CE 1 ATOM 1337 N NZ . LYS A 1 174 ? 4.111 36.624 57.198 1.00 52.05 ? 169 LYS L NZ 1 ATOM 1338 N N . ASP A 1 175 ? -0.920 35.134 52.844 1.00 25.50 ? 170 ASP L N 1 ATOM 1339 C CA . ASP A 1 175 ? -1.916 36.228 52.880 1.00 21.39 ? 170 ASP L CA 1 ATOM 1340 C C . ASP A 1 175 ? -3.193 36.051 52.027 1.00 19.16 ? 170 ASP L C 1 ATOM 1341 O O . ASP A 1 175 ? -3.873 37.009 51.663 1.00 17.11 ? 170 ASP L O 1 ATOM 1342 C CB . ASP A 1 175 ? -1.225 37.514 52.482 1.00 21.54 ? 170 ASP L CB 1 ATOM 1343 C CG . ASP A 1 175 ? -0.864 37.585 51.019 1.00 28.12 ? 170 ASP L CG 1 ATOM 1344 O OD1 . ASP A 1 175 ? -0.276 36.641 50.509 1.00 32.77 ? 170 ASP L OD1 1 ATOM 1345 O OD2 . ASP A 1 175 ? -1.190 38.590 50.391 1.00 32.74 ? 170 ASP L OD2 1 ATOM 1346 N N . SER A 1 176 ? -3.556 34.824 51.660 1.00 20.45 ? 171 SER L N 1 ATOM 1347 C CA . SER A 1 176 ? -4.743 34.483 50.889 1.00 19.90 ? 171 SER L CA 1 ATOM 1348 C C . SER A 1 176 ? -5.009 35.157 49.538 1.00 20.24 ? 171 SER L C 1 ATOM 1349 O O . SER A 1 176 ? -6.155 35.155 49.080 1.00 17.55 ? 171 SER L O 1 ATOM 1350 C CB . SER A 1 176 ? -5.950 34.675 51.805 1.00 23.29 ? 171 SER L CB 1 ATOM 1351 O OG . SER A 1 176 ? -5.767 34.062 53.080 1.00 27.99 ? 171 SER L OG 1 ATOM 1352 N N . THR A 1 177 ? -3.989 35.686 48.848 1.00 19.26 ? 172 THR L N 1 ATOM 1353 C CA . THR A 1 177 ? -4.116 36.310 47.524 1.00 13.86 ? 172 THR L CA 1 ATOM 1354 C C . THR A 1 177 ? -3.774 35.377 46.388 1.00 8.94 ? 172 THR L C 1 ATOM 1355 O O . THR A 1 177 ? -3.619 34.184 46.608 1.00 19.92 ? 172 THR L O 1 ATOM 1356 C CB . THR A 1 177 ? -3.213 37.503 47.434 1.00 8.76 ? 172 THR L CB 1 ATOM 1357 O OG1 . THR A 1 177 ? -2.097 37.174 48.218 1.00 12.23 ? 172 THR L OG1 1 ATOM 1358 C CG2 . THR A 1 177 ? -3.802 38.744 47.979 1.00 11.33 ? 172 THR L CG2 1 ATOM 1359 N N . TYR A 1 178 ? -3.698 35.819 45.159 1.00 5.22 ? 173 TYR L N 1 ATOM 1360 C CA . TYR A 1 178 ? -3.273 34.976 44.061 1.00 6.61 ? 173 TYR L CA 1 ATOM 1361 C C . TYR A 1 178 ? -2.355 35.827 43.222 1.00 10.03 ? 173 TYR L C 1 ATOM 1362 O O . TYR A 1 178 ? -2.235 37.058 43.418 1.00 16.07 ? 173 TYR L O 1 ATOM 1363 C CB . TYR A 1 178 ? -4.392 34.569 43.141 1.00 5.55 ? 173 TYR L CB 1 ATOM 1364 C CG . TYR A 1 178 ? -5.424 33.694 43.793 1.00 15.45 ? 173 TYR L CG 1 ATOM 1365 C CD1 . TYR A 1 178 ? -6.478 34.282 44.449 1.00 18.25 ? 173 TYR L CD1 1 ATOM 1366 C CD2 . TYR A 1 178 ? -5.300 32.317 43.716 1.00 21.42 ? 173 TYR L CD2 1 ATOM 1367 C CE1 . TYR A 1 178 ? -7.418 33.470 45.037 1.00 24.97 ? 173 TYR L CE1 1 ATOM 1368 C CE2 . TYR A 1 178 ? -6.237 31.500 44.304 1.00 23.36 ? 173 TYR L CE2 1 ATOM 1369 C CZ . TYR A 1 178 ? -7.292 32.094 44.958 1.00 25.17 ? 173 TYR L CZ 1 ATOM 1370 O OH . TYR A 1 178 ? -8.266 31.305 45.524 1.00 26.84 ? 173 TYR L OH 1 ATOM 1371 N N . SER A 1 179 ? -1.718 35.166 42.281 1.00 2.00 ? 174 SER L N 1 ATOM 1372 C CA . SER A 1 179 ? -0.951 35.883 41.333 1.00 3.39 ? 174 SER L CA 1 ATOM 1373 C C . SER A 1 179 ? -1.198 35.339 39.969 1.00 6.46 ? 174 SER L C 1 ATOM 1374 O O . SER A 1 179 ? -1.742 34.257 39.824 1.00 5.97 ? 174 SER L O 1 ATOM 1375 C CB . SER A 1 179 ? 0.445 35.778 41.721 1.00 2.00 ? 174 SER L CB 1 ATOM 1376 O OG . SER A 1 179 ? 0.544 36.881 42.608 1.00 7.39 ? 174 SER L OG 1 ATOM 1377 N N . MET A 1 180 ? -0.864 36.110 38.970 1.00 8.64 ? 175 MET L N 1 ATOM 1378 C CA . MET A 1 180 ? -1.204 35.707 37.649 1.00 10.03 ? 175 MET L CA 1 ATOM 1379 C C . MET A 1 180 ? -0.096 36.231 36.793 1.00 9.39 ? 175 MET L C 1 ATOM 1380 O O . MET A 1 180 ? 0.516 37.259 37.070 1.00 13.59 ? 175 MET L O 1 ATOM 1381 C CB . MET A 1 180 ? -2.500 36.346 37.292 1.00 17.56 ? 175 MET L CB 1 ATOM 1382 C CG . MET A 1 180 ? -3.313 35.426 36.455 1.00 22.45 ? 175 MET L CG 1 ATOM 1383 S SD . MET A 1 180 ? -3.062 35.514 34.678 1.00 28.59 ? 175 MET L SD 1 ATOM 1384 C CE . MET A 1 180 ? -4.252 36.799 34.606 1.00 20.68 ? 175 MET L CE 1 ATOM 1385 N N . SER A 1 181 ? 0.177 35.527 35.742 1.00 8.52 ? 176 SER L N 1 ATOM 1386 C CA . SER A 1 181 ? 1.165 35.960 34.823 1.00 10.34 ? 176 SER L CA 1 ATOM 1387 C C . SER A 1 181 ? 0.496 35.714 33.496 1.00 13.10 ? 176 SER L C 1 ATOM 1388 O O . SER A 1 181 ? -0.260 34.736 33.373 1.00 13.63 ? 176 SER L O 1 ATOM 1389 C CB . SER A 1 181 ? 2.339 35.100 35.065 1.00 17.82 ? 176 SER L CB 1 ATOM 1390 O OG . SER A 1 181 ? 3.442 35.345 34.218 1.00 32.56 ? 176 SER L OG 1 ATOM 1391 N N . SER A 1 182 ? 0.745 36.605 32.533 1.00 10.06 ? 177 SER L N 1 ATOM 1392 C CA . SER A 1 182 ? 0.278 36.432 31.188 1.00 3.43 ? 177 SER L CA 1 ATOM 1393 C C . SER A 1 182 ? 1.437 36.803 30.260 1.00 3.99 ? 177 SER L C 1 ATOM 1394 O O . SER A 1 182 ? 2.135 37.786 30.458 1.00 5.78 ? 177 SER L O 1 ATOM 1395 C CB . SER A 1 182 ? -0.888 37.307 31.035 1.00 4.84 ? 177 SER L CB 1 ATOM 1396 O OG . SER A 1 182 ? -1.409 36.969 29.769 1.00 5.97 ? 177 SER L OG 1 ATOM 1397 N N . THR A 1 183 ? 1.668 36.047 29.211 1.00 8.42 ? 178 THR L N 1 ATOM 1398 C CA . THR A 1 183 ? 2.851 36.197 28.368 1.00 12.95 ? 178 THR L CA 1 ATOM 1399 C C . THR A 1 183 ? 2.377 36.196 26.919 1.00 16.32 ? 178 THR L C 1 ATOM 1400 O O . THR A 1 183 ? 1.729 35.219 26.487 1.00 17.79 ? 178 THR L O 1 ATOM 1401 C CB . THR A 1 183 ? 3.826 34.988 28.631 1.00 13.86 ? 178 THR L CB 1 ATOM 1402 O OG1 . THR A 1 183 ? 4.177 35.025 30.022 1.00 17.07 ? 178 THR L OG1 1 ATOM 1403 C CG2 . THR A 1 183 ? 5.056 34.998 27.721 1.00 6.99 ? 178 THR L CG2 1 ATOM 1404 N N . LEU A 1 184 ? 2.670 37.255 26.158 1.00 14.59 ? 179 LEU L N 1 ATOM 1405 C CA . LEU A 1 184 ? 2.215 37.328 24.789 1.00 15.06 ? 179 LEU L CA 1 ATOM 1406 C C . LEU A 1 184 ? 3.423 36.880 24.032 1.00 17.23 ? 179 LEU L C 1 ATOM 1407 O O . LEU A 1 184 ? 4.437 37.556 24.219 1.00 23.19 ? 179 LEU L O 1 ATOM 1408 C CB . LEU A 1 184 ? 1.893 38.739 24.439 1.00 10.78 ? 179 LEU L CB 1 ATOM 1409 C CG . LEU A 1 184 ? 0.887 39.060 23.369 1.00 11.50 ? 179 LEU L CG 1 ATOM 1410 C CD1 . LEU A 1 184 ? 0.979 40.562 23.158 1.00 10.76 ? 179 LEU L CD1 1 ATOM 1411 C CD2 . LEU A 1 184 ? 1.157 38.349 22.066 1.00 2.00 ? 179 LEU L CD2 1 ATOM 1412 N N . THR A 1 185 ? 3.409 35.801 23.252 1.00 20.42 ? 180 THR L N 1 ATOM 1413 C CA . THR A 1 185 ? 4.627 35.476 22.522 1.00 27.12 ? 180 THR L CA 1 ATOM 1414 C C . THR A 1 185 ? 4.499 35.744 21.011 1.00 26.84 ? 180 THR L C 1 ATOM 1415 O O . THR A 1 185 ? 3.584 35.283 20.341 1.00 22.33 ? 180 THR L O 1 ATOM 1416 C CB . THR A 1 185 ? 4.966 34.006 22.836 1.00 31.10 ? 180 THR L CB 1 ATOM 1417 O OG1 . THR A 1 185 ? 4.948 33.858 24.258 1.00 30.39 ? 180 THR L OG1 1 ATOM 1418 C CG2 . THR A 1 185 ? 6.339 33.616 22.330 1.00 28.40 ? 180 THR L CG2 1 ATOM 1419 N N . LEU A 1 186 ? 5.386 36.525 20.430 1.00 26.08 ? 181 LEU L N 1 ATOM 1420 C CA . LEU A 1 186 ? 5.360 36.928 19.049 1.00 24.39 ? 181 LEU L CA 1 ATOM 1421 C C . LEU A 1 186 ? 6.749 36.676 18.507 1.00 26.88 ? 181 LEU L C 1 ATOM 1422 O O . LEU A 1 186 ? 7.692 36.351 19.235 1.00 29.55 ? 181 LEU L O 1 ATOM 1423 C CB . LEU A 1 186 ? 5.118 38.393 18.896 1.00 20.12 ? 181 LEU L CB 1 ATOM 1424 C CG . LEU A 1 186 ? 3.915 39.059 19.436 1.00 16.83 ? 181 LEU L CG 1 ATOM 1425 C CD1 . LEU A 1 186 ? 4.034 40.519 19.047 1.00 21.18 ? 181 LEU L CD1 1 ATOM 1426 C CD2 . LEU A 1 186 ? 2.658 38.490 18.855 1.00 11.81 ? 181 LEU L CD2 1 ATOM 1427 N N . THR A 1 187 ? 6.895 36.846 17.198 1.00 25.20 ? 182 THR L N 1 ATOM 1428 C CA . THR A 1 187 ? 8.201 36.721 16.580 1.00 22.74 ? 182 THR L CA 1 ATOM 1429 C C . THR A 1 187 ? 8.782 38.119 16.625 1.00 23.45 ? 182 THR L C 1 ATOM 1430 O O . THR A 1 187 ? 8.012 39.088 16.769 1.00 15.50 ? 182 THR L O 1 ATOM 1431 C CB . THR A 1 187 ? 8.109 36.301 15.117 1.00 22.47 ? 182 THR L CB 1 ATOM 1432 O OG1 . THR A 1 187 ? 7.369 37.316 14.434 1.00 21.13 ? 182 THR L OG1 1 ATOM 1433 C CG2 . THR A 1 187 ? 7.451 34.942 14.956 1.00 21.57 ? 182 THR L CG2 1 ATOM 1434 N N . LYS A 1 188 ? 10.099 38.194 16.391 1.00 20.65 ? 183 LYS L N 1 ATOM 1435 C CA . LYS A 1 188 ? 10.799 39.448 16.284 1.00 17.50 ? 183 LYS L CA 1 ATOM 1436 C C . LYS A 1 188 ? 10.094 40.289 15.209 1.00 22.33 ? 183 LYS L C 1 ATOM 1437 O O . LYS A 1 188 ? 9.658 41.400 15.498 1.00 21.30 ? 183 LYS L O 1 ATOM 1438 C CB . LYS A 1 188 ? 12.249 39.184 15.895 1.00 19.62 ? 183 LYS L CB 1 ATOM 1439 C CG . LYS A 1 188 ? 13.221 40.272 16.343 1.00 25.37 ? 183 LYS L CG 1 ATOM 1440 C CD . LYS A 1 188 ? 14.278 40.637 15.296 1.00 30.04 ? 183 LYS L CD 1 ATOM 1441 C CE . LYS A 1 188 ? 15.442 39.661 15.204 1.00 33.99 ? 183 LYS L CE 1 ATOM 1442 N NZ . LYS A 1 188 ? 16.400 39.844 16.281 1.00 36.29 ? 183 LYS L NZ 1 ATOM 1443 N N . ASP A 1 189 ? 9.804 39.792 14.004 1.00 23.75 ? 184 ASP L N 1 ATOM 1444 C CA . ASP A 1 189 ? 9.213 40.644 12.960 1.00 28.43 ? 184 ASP L CA 1 ATOM 1445 C C . ASP A 1 189 ? 7.894 41.271 13.350 1.00 24.36 ? 184 ASP L C 1 ATOM 1446 O O . ASP A 1 189 ? 7.746 42.493 13.357 1.00 24.72 ? 184 ASP L O 1 ATOM 1447 C CB . ASP A 1 189 ? 8.962 39.878 11.656 1.00 29.79 ? 184 ASP L CB 1 ATOM 1448 C CG . ASP A 1 189 ? 10.221 39.277 11.067 1.00 37.32 ? 184 ASP L CG 1 ATOM 1449 O OD1 . ASP A 1 189 ? 11.067 38.764 11.804 1.00 40.20 ? 184 ASP L OD1 1 ATOM 1450 O OD2 . ASP A 1 189 ? 10.348 39.313 9.849 1.00 44.20 ? 184 ASP L OD2 1 ATOM 1451 N N . GLU A 1 190 ? 6.995 40.391 13.787 1.00 24.32 ? 185 GLU L N 1 ATOM 1452 C CA . GLU A 1 190 ? 5.648 40.730 14.198 1.00 21.32 ? 185 GLU L CA 1 ATOM 1453 C C . GLU A 1 190 ? 5.720 41.812 15.271 1.00 22.47 ? 185 GLU L C 1 ATOM 1454 O O . GLU A 1 190 ? 4.994 42.820 15.213 1.00 19.77 ? 185 GLU L O 1 ATOM 1455 C CB . GLU A 1 190 ? 4.984 39.480 14.750 1.00 32.08 ? 185 GLU L CB 1 ATOM 1456 C CG . GLU A 1 190 ? 3.533 39.200 14.384 1.00 44.96 ? 185 GLU L CG 1 ATOM 1457 C CD . GLU A 1 190 ? 2.592 40.379 14.617 1.00 56.63 ? 185 GLU L CD 1 ATOM 1458 O OE1 . GLU A 1 190 ? 2.437 41.184 13.697 1.00 56.39 ? 185 GLU L OE1 1 ATOM 1459 O OE2 . GLU A 1 190 ? 2.018 40.489 15.705 1.00 65.77 ? 185 GLU L OE2 1 ATOM 1460 N N . TYR A 1 191 ? 6.681 41.558 16.183 1.00 21.71 ? 186 TYR L N 1 ATOM 1461 C CA . TYR A 1 191 ? 6.983 42.362 17.336 1.00 9.60 ? 186 TYR L CA 1 ATOM 1462 C C . TYR A 1 191 ? 7.416 43.685 16.847 1.00 8.01 ? 186 TYR L C 1 ATOM 1463 O O . TYR A 1 191 ? 6.925 44.687 17.337 1.00 14.90 ? 186 TYR L O 1 ATOM 1464 C CB . TYR A 1 191 ? 8.124 41.793 18.193 1.00 5.27 ? 186 TYR L CB 1 ATOM 1465 C CG . TYR A 1 191 ? 8.556 42.792 19.246 1.00 12.15 ? 186 TYR L CG 1 ATOM 1466 C CD1 . TYR A 1 191 ? 7.623 43.268 20.145 1.00 18.72 ? 186 TYR L CD1 1 ATOM 1467 C CD2 . TYR A 1 191 ? 9.837 43.294 19.265 1.00 15.64 ? 186 TYR L CD2 1 ATOM 1468 C CE1 . TYR A 1 191 ? 7.931 44.249 21.063 1.00 16.61 ? 186 TYR L CE1 1 ATOM 1469 C CE2 . TYR A 1 191 ? 10.162 44.279 20.181 1.00 17.20 ? 186 TYR L CE2 1 ATOM 1470 C CZ . TYR A 1 191 ? 9.204 44.740 21.072 1.00 17.04 ? 186 TYR L CZ 1 ATOM 1471 O OH . TYR A 1 191 ? 9.512 45.688 22.018 1.00 17.34 ? 186 TYR L OH 1 ATOM 1472 N N . GLU A 1 192 ? 8.313 43.716 15.897 1.00 10.01 ? 187 GLU L N 1 ATOM 1473 C CA . GLU A 1 192 ? 8.833 45.005 15.550 1.00 21.80 ? 187 GLU L CA 1 ATOM 1474 C C . GLU A 1 192 ? 7.907 45.770 14.619 1.00 25.59 ? 187 GLU L C 1 ATOM 1475 O O . GLU A 1 192 ? 8.180 46.931 14.319 1.00 30.31 ? 187 GLU L O 1 ATOM 1476 C CB . GLU A 1 192 ? 10.226 44.797 14.962 1.00 28.79 ? 187 GLU L CB 1 ATOM 1477 C CG . GLU A 1 192 ? 11.162 44.158 16.000 1.00 32.52 ? 187 GLU L CG 1 ATOM 1478 C CD . GLU A 1 192 ? 12.651 44.250 15.712 1.00 35.92 ? 187 GLU L CD 1 ATOM 1479 O OE1 . GLU A 1 192 ? 13.089 43.831 14.638 1.00 38.70 ? 187 GLU L OE1 1 ATOM 1480 O OE2 . GLU A 1 192 ? 13.372 44.741 16.581 1.00 36.50 ? 187 GLU L OE2 1 ATOM 1481 N N . ARG A 1 193 ? 6.791 45.200 14.157 1.00 24.98 ? 188 ARG L N 1 ATOM 1482 C CA . ARG A 1 193 ? 5.864 45.935 13.292 1.00 28.93 ? 188 ARG L CA 1 ATOM 1483 C C . ARG A 1 193 ? 5.017 47.005 13.977 1.00 31.03 ? 188 ARG L C 1 ATOM 1484 O O . ARG A 1 193 ? 4.461 47.951 13.387 1.00 34.30 ? 188 ARG L O 1 ATOM 1485 C CB . ARG A 1 193 ? 4.857 45.034 12.642 1.00 26.43 ? 188 ARG L CB 1 ATOM 1486 C CG . ARG A 1 193 ? 5.505 43.993 11.818 1.00 26.61 ? 188 ARG L CG 1 ATOM 1487 C CD . ARG A 1 193 ? 4.403 43.132 11.256 1.00 29.07 ? 188 ARG L CD 1 ATOM 1488 N NE . ARG A 1 193 ? 5.026 41.896 10.876 1.00 33.68 ? 188 ARG L NE 1 ATOM 1489 C CZ . ARG A 1 193 ? 5.858 41.835 9.845 1.00 39.80 ? 188 ARG L CZ 1 ATOM 1490 N NH1 . ARG A 1 193 ? 6.064 42.886 9.009 1.00 35.38 ? 188 ARG L NH1 1 ATOM 1491 N NH2 . ARG A 1 193 ? 6.458 40.656 9.677 1.00 41.96 ? 188 ARG L NH2 1 ATOM 1492 N N . HIS A 1 194 ? 4.807 46.742 15.255 1.00 25.01 ? 189 HIS L N 1 ATOM 1493 C CA . HIS A 1 194 ? 3.842 47.523 15.952 1.00 21.00 ? 189 HIS L CA 1 ATOM 1494 C C . HIS A 1 194 ? 4.563 48.476 16.887 1.00 22.87 ? 189 HIS L C 1 ATOM 1495 O O . HIS A 1 194 ? 5.781 48.518 16.837 1.00 26.33 ? 189 HIS L O 1 ATOM 1496 C CB . HIS A 1 194 ? 2.948 46.476 16.572 1.00 21.01 ? 189 HIS L CB 1 ATOM 1497 C CG . HIS A 1 194 ? 2.262 45.508 15.572 1.00 21.33 ? 189 HIS L CG 1 ATOM 1498 N ND1 . HIS A 1 194 ? 2.565 44.235 15.243 1.00 16.73 ? 189 HIS L ND1 1 ATOM 1499 C CD2 . HIS A 1 194 ? 1.121 45.827 14.879 1.00 16.03 ? 189 HIS L CD2 1 ATOM 1500 C CE1 . HIS A 1 194 ? 1.669 43.795 14.420 1.00 11.07 ? 189 HIS L CE1 1 ATOM 1501 N NE2 . HIS A 1 194 ? 0.811 44.757 14.208 1.00 17.45 ? 189 HIS L NE2 1 ATOM 1502 N N . ASN A 1 195 ? 3.923 49.340 17.685 1.00 23.83 ? 190 ASN L N 1 ATOM 1503 C CA . ASN A 1 195 ? 4.642 50.291 18.520 1.00 21.78 ? 190 ASN L CA 1 ATOM 1504 C C . ASN A 1 195 ? 4.127 50.194 19.941 1.00 25.75 ? 190 ASN L C 1 ATOM 1505 O O . ASN A 1 195 ? 4.899 49.906 20.845 1.00 26.00 ? 190 ASN L O 1 ATOM 1506 C CB . ASN A 1 195 ? 4.473 51.702 17.974 1.00 27.94 ? 190 ASN L CB 1 ATOM 1507 C CG . ASN A 1 195 ? 5.247 51.894 16.652 1.00 44.37 ? 190 ASN L CG 1 ATOM 1508 O OD1 . ASN A 1 195 ? 6.282 52.562 16.600 1.00 49.90 ? 190 ASN L OD1 1 ATOM 1509 N ND2 . ASN A 1 195 ? 4.846 51.386 15.479 1.00 47.93 ? 190 ASN L ND2 1 ATOM 1510 N N . SER A 1 196 ? 2.846 50.320 20.256 1.00 26.09 ? 191 SER L N 1 ATOM 1511 C CA . SER A 1 196 ? 2.395 50.287 21.643 1.00 20.69 ? 191 SER L CA 1 ATOM 1512 C C . SER A 1 196 ? 1.895 48.902 21.957 1.00 16.49 ? 191 SER L C 1 ATOM 1513 O O . SER A 1 196 ? 1.220 48.351 21.082 1.00 11.74 ? 191 SER L O 1 ATOM 1514 C CB . SER A 1 196 ? 1.292 51.358 21.808 1.00 28.03 ? 191 SER L CB 1 ATOM 1515 O OG . SER A 1 196 ? 0.847 51.944 20.558 1.00 36.74 ? 191 SER L OG 1 ATOM 1516 N N . TYR A 1 197 ? 2.280 48.337 23.114 1.00 13.63 ? 192 TYR L N 1 ATOM 1517 C CA . TYR A 1 197 ? 1.851 47.025 23.617 1.00 2.10 ? 192 TYR L CA 1 ATOM 1518 C C . TYR A 1 197 ? 1.151 47.201 24.986 1.00 6.41 ? 192 TYR L C 1 ATOM 1519 O O . TYR A 1 197 ? 1.532 48.064 25.804 1.00 2.31 ? 192 TYR L O 1 ATOM 1520 C CB . TYR A 1 197 ? 3.077 46.175 23.712 1.00 3.35 ? 192 TYR L CB 1 ATOM 1521 C CG . TYR A 1 197 ? 3.630 45.721 22.355 1.00 9.93 ? 192 TYR L CG 1 ATOM 1522 C CD1 . TYR A 1 197 ? 4.453 46.512 21.565 1.00 3.76 ? 192 TYR L CD1 1 ATOM 1523 C CD2 . TYR A 1 197 ? 3.257 44.466 21.929 1.00 10.94 ? 192 TYR L CD2 1 ATOM 1524 C CE1 . TYR A 1 197 ? 4.871 46.036 20.352 1.00 3.90 ? 192 TYR L CE1 1 ATOM 1525 C CE2 . TYR A 1 197 ? 3.672 43.985 20.723 1.00 10.37 ? 192 TYR L CE2 1 ATOM 1526 C CZ . TYR A 1 197 ? 4.467 44.782 19.945 1.00 11.79 ? 192 TYR L CZ 1 ATOM 1527 O OH . TYR A 1 197 ? 4.751 44.298 18.688 1.00 16.58 ? 192 TYR L OH 1 ATOM 1528 N N . THR A 1 198 ? 0.129 46.396 25.300 1.00 6.99 ? 193 THR L N 1 ATOM 1529 C CA . THR A 1 198 ? -0.784 46.696 26.390 1.00 9.74 ? 193 THR L CA 1 ATOM 1530 C C . THR A 1 198 ? -1.277 45.469 27.084 1.00 11.64 ? 193 THR L C 1 ATOM 1531 O O . THR A 1 198 ? -1.706 44.489 26.476 1.00 16.25 ? 193 THR L O 1 ATOM 1532 C CB . THR A 1 198 ? -2.024 47.438 25.862 1.00 15.50 ? 193 THR L CB 1 ATOM 1533 O OG1 . THR A 1 198 ? -1.474 48.452 25.022 1.00 25.06 ? 193 THR L OG1 1 ATOM 1534 C CG2 . THR A 1 198 ? -2.959 48.044 26.911 1.00 10.98 ? 193 THR L CG2 1 ATOM 1535 N N . CYS A 1 199 ? -1.338 45.640 28.379 1.00 11.80 ? 194 CYS L N 1 ATOM 1536 C CA . CYS A 1 199 ? -1.752 44.629 29.300 1.00 9.29 ? 194 CYS L CA 1 ATOM 1537 C C . CYS A 1 199 ? -3.041 45.171 29.947 1.00 11.73 ? 194 CYS L C 1 ATOM 1538 O O . CYS A 1 199 ? -2.980 46.138 30.727 1.00 7.73 ? 194 CYS L O 1 ATOM 1539 C CB . CYS A 1 199 ? -0.558 44.513 30.207 1.00 11.80 ? 194 CYS L CB 1 ATOM 1540 S SG . CYS A 1 199 ? -1.002 43.316 31.454 1.00 18.53 ? 194 CYS L SG 1 ATOM 1541 N N . GLU A 1 200 ? -4.253 44.678 29.640 1.00 10.82 ? 195 GLU L N 1 ATOM 1542 C CA . GLU A 1 200 ? -5.469 45.231 30.248 1.00 9.83 ? 195 GLU L CA 1 ATOM 1543 C C . GLU A 1 200 ? -6.187 44.312 31.269 1.00 13.97 ? 195 GLU L C 1 ATOM 1544 O O . GLU A 1 200 ? -6.702 43.224 30.952 1.00 17.01 ? 195 GLU L O 1 ATOM 1545 C CB . GLU A 1 200 ? -6.377 45.602 29.102 1.00 8.31 ? 195 GLU L CB 1 ATOM 1546 C CG . GLU A 1 200 ? -7.499 46.445 29.650 1.00 14.01 ? 195 GLU L CG 1 ATOM 1547 C CD . GLU A 1 200 ? -8.290 47.241 28.652 1.00 15.03 ? 195 GLU L CD 1 ATOM 1548 O OE1 . GLU A 1 200 ? -7.697 47.869 27.772 1.00 21.58 ? 195 GLU L OE1 1 ATOM 1549 O OE2 . GLU A 1 200 ? -9.504 47.237 28.794 1.00 17.40 ? 195 GLU L OE2 1 ATOM 1550 N N . ALA A 1 201 ? -6.256 44.716 32.526 1.00 9.22 ? 196 ALA L N 1 ATOM 1551 C CA . ALA A 1 201 ? -6.840 43.861 33.548 1.00 16.63 ? 196 ALA L CA 1 ATOM 1552 C C . ALA A 1 201 ? -8.273 44.227 33.961 1.00 18.38 ? 196 ALA L C 1 ATOM 1553 O O . ALA A 1 201 ? -8.546 45.398 34.226 1.00 15.48 ? 196 ALA L O 1 ATOM 1554 C CB . ALA A 1 201 ? -5.922 43.907 34.775 1.00 9.47 ? 196 ALA L CB 1 ATOM 1555 N N . THR A 1 202 ? -9.258 43.350 34.027 1.00 21.91 ? 197 THR L N 1 ATOM 1556 C CA . THR A 1 202 ? -10.543 43.753 34.574 1.00 26.59 ? 197 THR L CA 1 ATOM 1557 C C . THR A 1 202 ? -10.867 42.778 35.706 1.00 27.26 ? 197 THR L C 1 ATOM 1558 O O . THR A 1 202 ? -10.779 41.558 35.521 1.00 24.15 ? 197 THR L O 1 ATOM 1559 C CB . THR A 1 202 ? -11.586 43.746 33.437 1.00 26.52 ? 197 THR L CB 1 ATOM 1560 O OG1 . THR A 1 202 ? -10.968 43.517 32.170 1.00 29.55 ? 197 THR L OG1 1 ATOM 1561 C CG2 . THR A 1 202 ? -12.273 45.098 33.434 1.00 19.92 ? 197 THR L CG2 1 ATOM 1562 N N . HIS A 1 203 ? -11.214 43.280 36.904 1.00 29.09 ? 198 HIS L N 1 ATOM 1563 C CA . HIS A 1 203 ? -11.339 42.477 38.136 1.00 32.37 ? 198 HIS L CA 1 ATOM 1564 C C . HIS A 1 203 ? -12.110 43.154 39.281 1.00 34.29 ? 198 HIS L C 1 ATOM 1565 O O . HIS A 1 203 ? -11.630 44.203 39.731 1.00 40.78 ? 198 HIS L O 1 ATOM 1566 C CB . HIS A 1 203 ? -9.906 42.126 38.620 1.00 28.65 ? 198 HIS L CB 1 ATOM 1567 C CG . HIS A 1 203 ? -9.748 41.770 40.077 1.00 17.74 ? 198 HIS L CG 1 ATOM 1568 N ND1 . HIS A 1 203 ? -9.663 42.621 41.077 1.00 13.20 ? 198 HIS L ND1 1 ATOM 1569 C CD2 . HIS A 1 203 ? -9.725 40.517 40.569 1.00 17.81 ? 198 HIS L CD2 1 ATOM 1570 C CE1 . HIS A 1 203 ? -9.607 41.929 42.179 1.00 12.11 ? 198 HIS L CE1 1 ATOM 1571 N NE2 . HIS A 1 203 ? -9.642 40.677 41.858 1.00 21.01 ? 198 HIS L NE2 1 ATOM 1572 N N . LYS A 1 204 ? -13.109 42.502 39.908 1.00 30.31 ? 199 LYS L N 1 ATOM 1573 C CA . LYS A 1 204 ? -14.001 43.091 40.922 1.00 28.13 ? 199 LYS L CA 1 ATOM 1574 C C . LYS A 1 204 ? -13.626 44.326 41.751 1.00 26.52 ? 199 LYS L C 1 ATOM 1575 O O . LYS A 1 204 ? -14.445 45.212 41.927 1.00 22.96 ? 199 LYS L O 1 ATOM 1576 C CB . LYS A 1 204 ? -14.397 41.966 41.850 1.00 29.56 ? 199 LYS L CB 1 ATOM 1577 C CG . LYS A 1 204 ? -15.344 42.388 42.955 1.00 36.67 ? 199 LYS L CG 1 ATOM 1578 C CD . LYS A 1 204 ? -15.839 41.151 43.683 1.00 44.79 ? 199 LYS L CD 1 ATOM 1579 C CE . LYS A 1 204 ? -16.832 41.530 44.795 1.00 47.24 ? 199 LYS L CE 1 ATOM 1580 N NZ . LYS A 1 204 ? -16.190 41.985 46.016 1.00 45.47 ? 199 LYS L NZ 1 ATOM 1581 N N . THR A 1 205 ? -12.416 44.413 42.293 1.00 29.62 ? 200 THR L N 1 ATOM 1582 C CA . THR A 1 205 ? -11.966 45.580 43.032 1.00 33.06 ? 200 THR L CA 1 ATOM 1583 C C . THR A 1 205 ? -12.081 46.917 42.283 1.00 41.66 ? 200 THR L C 1 ATOM 1584 O O . THR A 1 205 ? -12.269 47.960 42.916 1.00 51.06 ? 200 THR L O 1 ATOM 1585 C CB . THR A 1 205 ? -10.493 45.340 43.478 1.00 31.03 ? 200 THR L CB 1 ATOM 1586 O OG1 . THR A 1 205 ? -9.732 44.912 42.336 1.00 27.54 ? 200 THR L OG1 1 ATOM 1587 C CG2 . THR A 1 205 ? -10.437 44.296 44.545 1.00 31.05 ? 200 THR L CG2 1 ATOM 1588 N N . SER A 1 206 ? -11.935 46.968 40.961 1.00 45.40 ? 201 SER L N 1 ATOM 1589 C CA . SER A 1 206 ? -12.014 48.232 40.266 1.00 44.16 ? 201 SER L CA 1 ATOM 1590 C C . SER A 1 206 ? -13.119 48.053 39.279 1.00 43.01 ? 201 SER L C 1 ATOM 1591 O O . SER A 1 206 ? -13.336 46.993 38.688 1.00 43.08 ? 201 SER L O 1 ATOM 1592 C CB . SER A 1 206 ? -10.753 48.572 39.472 1.00 48.01 ? 201 SER L CB 1 ATOM 1593 O OG . SER A 1 206 ? -9.616 48.793 40.288 1.00 54.16 ? 201 SER L OG 1 ATOM 1594 N N . THR A 1 207 ? -13.775 49.182 39.150 1.00 43.65 ? 202 THR L N 1 ATOM 1595 C CA . THR A 1 207 ? -14.805 49.320 38.157 1.00 43.35 ? 202 THR L CA 1 ATOM 1596 C C . THR A 1 207 ? -14.226 49.951 36.868 1.00 39.04 ? 202 THR L C 1 ATOM 1597 O O . THR A 1 207 ? -14.976 50.213 35.930 1.00 40.24 ? 202 THR L O 1 ATOM 1598 C CB . THR A 1 207 ? -15.910 50.111 38.914 1.00 45.97 ? 202 THR L CB 1 ATOM 1599 O OG1 . THR A 1 207 ? -17.124 49.483 38.511 1.00 46.29 ? 202 THR L OG1 1 ATOM 1600 C CG2 . THR A 1 207 ? -15.859 51.633 38.714 1.00 43.01 ? 202 THR L CG2 1 ATOM 1601 N N . SER A 1 208 ? -12.926 50.259 36.744 1.00 35.74 ? 203 SER L N 1 ATOM 1602 C CA . SER A 1 208 ? -12.381 50.591 35.432 1.00 32.84 ? 203 SER L CA 1 ATOM 1603 C C . SER A 1 208 ? -11.320 49.520 35.195 1.00 28.57 ? 203 SER L C 1 ATOM 1604 O O . SER A 1 208 ? -10.788 48.936 36.149 1.00 29.46 ? 203 SER L O 1 ATOM 1605 C CB . SER A 1 208 ? -11.723 51.964 35.384 1.00 33.99 ? 203 SER L CB 1 ATOM 1606 O OG . SER A 1 208 ? -10.466 52.118 36.030 1.00 37.96 ? 203 SER L OG 1 ATOM 1607 N N . PRO A 1 209 ? -11.057 49.143 33.960 1.00 21.57 ? 204 PRO L N 1 ATOM 1608 C CA . PRO A 1 209 ? -9.905 48.353 33.590 1.00 19.55 ? 204 PRO L CA 1 ATOM 1609 C C . PRO A 1 209 ? -8.617 48.862 34.189 1.00 16.83 ? 204 PRO L C 1 ATOM 1610 O O . PRO A 1 209 ? -8.547 50.060 34.402 1.00 25.83 ? 204 PRO L O 1 ATOM 1611 C CB . PRO A 1 209 ? -9.919 48.397 32.096 1.00 19.12 ? 204 PRO L CB 1 ATOM 1612 C CG . PRO A 1 209 ? -11.148 49.201 31.691 1.00 23.17 ? 204 PRO L CG 1 ATOM 1613 C CD . PRO A 1 209 ? -12.042 49.115 32.901 1.00 22.42 ? 204 PRO L CD 1 ATOM 1614 N N . ILE A 1 210 ? -7.604 48.044 34.465 1.00 13.20 ? 205 ILE L N 1 ATOM 1615 C CA . ILE A 1 210 ? -6.333 48.511 34.999 1.00 17.71 ? 205 ILE L CA 1 ATOM 1616 C C . ILE A 1 210 ? -5.443 48.376 33.782 1.00 16.28 ? 205 ILE L C 1 ATOM 1617 O O . ILE A 1 210 ? -5.241 47.234 33.370 1.00 22.24 ? 205 ILE L O 1 ATOM 1618 C CB . ILE A 1 210 ? -5.828 47.603 36.136 1.00 20.05 ? 205 ILE L CB 1 ATOM 1619 C CG1 . ILE A 1 210 ? -6.971 47.338 37.122 1.00 21.71 ? 205 ILE L CG1 1 ATOM 1620 C CG2 . ILE A 1 210 ? -4.609 48.262 36.792 1.00 12.86 ? 205 ILE L CG2 1 ATOM 1621 C CD1 . ILE A 1 210 ? -6.650 46.532 38.389 1.00 23.72 ? 205 ILE L CD1 1 ATOM 1622 N N . VAL A 1 211 ? -4.938 49.435 33.148 1.00 9.63 ? 206 VAL L N 1 ATOM 1623 C CA . VAL A 1 211 ? -4.262 49.252 31.876 1.00 11.72 ? 206 VAL L CA 1 ATOM 1624 C C . VAL A 1 211 ? -2.789 49.511 32.045 1.00 13.30 ? 206 VAL L C 1 ATOM 1625 O O . VAL A 1 211 ? -2.456 50.416 32.806 1.00 22.69 ? 206 VAL L O 1 ATOM 1626 C CB . VAL A 1 211 ? -4.891 50.204 30.847 1.00 11.83 ? 206 VAL L CB 1 ATOM 1627 C CG1 . VAL A 1 211 ? -4.364 50.007 29.444 1.00 8.77 ? 206 VAL L CG1 1 ATOM 1628 C CG2 . VAL A 1 211 ? -6.362 49.872 30.774 1.00 16.46 ? 206 VAL L CG2 1 ATOM 1629 N N . LYS A 1 212 ? -1.883 48.781 31.400 1.00 11.41 ? 207 LYS L N 1 ATOM 1630 C CA . LYS A 1 212 ? -0.464 48.992 31.590 1.00 7.65 ? 207 LYS L CA 1 ATOM 1631 C C . LYS A 1 212 ? 0.148 48.820 30.216 1.00 12.44 ? 207 LYS L C 1 ATOM 1632 O O . LYS A 1 212 ? -0.069 47.783 29.566 1.00 14.41 ? 207 LYS L O 1 ATOM 1633 C CB . LYS A 1 212 ? 0.058 47.962 32.513 1.00 5.62 ? 207 LYS L CB 1 ATOM 1634 C CG . LYS A 1 212 ? 0.935 48.552 33.559 1.00 7.28 ? 207 LYS L CG 1 ATOM 1635 C CD . LYS A 1 212 ? 0.224 49.048 34.805 1.00 4.46 ? 207 LYS L CD 1 ATOM 1636 C CE . LYS A 1 212 ? 1.436 49.600 35.556 1.00 13.69 ? 207 LYS L CE 1 ATOM 1637 N NZ . LYS A 1 212 ? 1.114 50.334 36.766 1.00 20.07 ? 207 LYS L NZ 1 ATOM 1638 N N . SER A 1 213 ? 0.890 49.823 29.740 1.00 12.76 ? 208 SER L N 1 ATOM 1639 C CA . SER A 1 213 ? 1.462 49.804 28.404 1.00 13.36 ? 208 SER L CA 1 ATOM 1640 C C . SER A 1 213 ? 2.860 50.299 28.295 1.00 15.16 ? 208 SER L C 1 ATOM 1641 O O . SER A 1 213 ? 3.286 50.961 29.230 1.00 13.99 ? 208 SER L O 1 ATOM 1642 C CB . SER A 1 213 ? 0.671 50.628 27.459 1.00 12.14 ? 208 SER L CB 1 ATOM 1643 O OG . SER A 1 213 ? -0.257 49.663 27.057 1.00 19.70 ? 208 SER L OG 1 ATOM 1644 N N . PHE A 1 214 ? 3.562 49.944 27.212 1.00 16.68 ? 209 PHE L N 1 ATOM 1645 C CA . PHE A 1 214 ? 4.881 50.468 26.933 1.00 15.23 ? 209 PHE L CA 1 ATOM 1646 C C . PHE A 1 214 ? 4.941 50.739 25.425 1.00 18.10 ? 209 PHE L C 1 ATOM 1647 O O . PHE A 1 214 ? 4.330 49.968 24.664 1.00 20.44 ? 209 PHE L O 1 ATOM 1648 C CB . PHE A 1 214 ? 5.923 49.434 27.402 1.00 13.78 ? 209 PHE L CB 1 ATOM 1649 C CG . PHE A 1 214 ? 6.151 48.160 26.600 1.00 10.46 ? 209 PHE L CG 1 ATOM 1650 C CD1 . PHE A 1 214 ? 7.045 48.141 25.548 1.00 9.64 ? 209 PHE L CD1 1 ATOM 1651 C CD2 . PHE A 1 214 ? 5.526 47.000 26.969 1.00 12.55 ? 209 PHE L CD2 1 ATOM 1652 C CE1 . PHE A 1 214 ? 7.315 46.967 24.877 1.00 10.98 ? 209 PHE L CE1 1 ATOM 1653 C CE2 . PHE A 1 214 ? 5.805 45.833 26.292 1.00 12.79 ? 209 PHE L CE2 1 ATOM 1654 C CZ . PHE A 1 214 ? 6.698 45.803 25.249 1.00 9.96 ? 209 PHE L CZ 1 ATOM 1655 N N . ASN A 1 215 ? 5.564 51.816 24.917 1.00 20.51 ? 210 ASN L N 1 ATOM 1656 C CA . ASN A 1 215 ? 5.657 51.994 23.464 1.00 26.19 ? 210 ASN L CA 1 ATOM 1657 C C . ASN A 1 215 ? 6.966 51.391 23.075 1.00 28.54 ? 210 ASN L C 1 ATOM 1658 O O . ASN A 1 215 ? 7.948 51.669 23.764 1.00 34.77 ? 210 ASN L O 1 ATOM 1659 C CB . ASN A 1 215 ? 5.713 53.410 23.049 1.00 32.73 ? 210 ASN L CB 1 ATOM 1660 C CG . ASN A 1 215 ? 4.362 54.053 23.138 1.00 45.05 ? 210 ASN L CG 1 ATOM 1661 O OD1 . ASN A 1 215 ? 3.517 53.665 23.942 1.00 52.62 ? 210 ASN L OD1 1 ATOM 1662 N ND2 . ASN A 1 215 ? 4.102 55.070 22.326 1.00 54.17 ? 210 ASN L ND2 1 ATOM 1663 N N . ARG A 1 216 ? 7.097 50.697 21.965 1.00 23.55 ? 211 ARG L N 1 ATOM 1664 C CA . ARG A 1 216 ? 8.282 49.931 21.742 1.00 21.56 ? 211 ARG L CA 1 ATOM 1665 C C . ARG A 1 216 ? 9.357 50.629 20.974 1.00 29.08 ? 211 ARG L C 1 ATOM 1666 O O . ARG A 1 216 ? 9.831 50.167 19.939 1.00 33.58 ? 211 ARG L O 1 ATOM 1667 C CB . ARG A 1 216 ? 7.901 48.642 21.044 1.00 20.79 ? 211 ARG L CB 1 ATOM 1668 C CG . ARG A 1 216 ? 7.341 48.652 19.648 1.00 12.92 ? 211 ARG L CG 1 ATOM 1669 C CD . ARG A 1 216 ? 7.862 47.453 18.938 1.00 12.03 ? 211 ARG L CD 1 ATOM 1670 N NE . ARG A 1 216 ? 9.265 47.659 18.694 1.00 18.76 ? 211 ARG L NE 1 ATOM 1671 C CZ . ARG A 1 216 ? 9.706 48.137 17.512 1.00 25.93 ? 211 ARG L CZ 1 ATOM 1672 N NH1 . ARG A 1 216 ? 8.880 48.504 16.533 1.00 20.57 ? 211 ARG L NH1 1 ATOM 1673 N NH2 . ARG A 1 216 ? 11.019 48.264 17.291 1.00 29.75 ? 211 ARG L NH2 1 ATOM 1674 N N . ASN A 1 217 ? 9.792 51.750 21.522 1.00 39.19 ? 212 ASN L N 1 ATOM 1675 C CA . ASN A 1 217 ? 10.802 52.620 20.909 1.00 52.32 ? 212 ASN L CA 1 ATOM 1676 C C . ASN A 1 217 ? 10.912 53.955 21.618 1.00 56.96 ? 212 ASN L C 1 ATOM 1677 O O . ASN A 1 217 ? 11.824 54.708 21.292 1.00 62.15 ? 212 ASN L O 1 ATOM 1678 C CB . ASN A 1 217 ? 10.525 52.958 19.412 1.00 54.47 ? 212 ASN L CB 1 ATOM 1679 C CG . ASN A 1 217 ? 9.066 53.233 19.042 1.00 60.39 ? 212 ASN L CG 1 ATOM 1680 O OD1 . ASN A 1 217 ? 8.163 53.405 19.873 1.00 61.58 ? 212 ASN L OD1 1 ATOM 1681 N ND2 . ASN A 1 217 ? 8.788 53.209 17.754 1.00 62.81 ? 212 ASN L ND2 1 ATOM 1682 N N . GLU A 1 218 ? 10.048 54.282 22.583 1.00 61.56 ? 213 GLU L N 1 ATOM 1683 C CA . GLU A 1 218 ? 10.059 55.569 23.266 1.00 68.36 ? 213 GLU L CA 1 ATOM 1684 C C . GLU A 1 218 ? 11.366 55.960 23.957 1.00 75.63 ? 213 GLU L C 1 ATOM 1685 O O . GLU A 1 218 ? 11.878 55.309 24.881 1.00 73.44 ? 213 GLU L O 1 ATOM 1686 C CB . GLU A 1 218 ? 8.960 55.588 24.272 1.00 64.67 ? 213 GLU L CB 1 ATOM 1687 C CG . GLU A 1 218 ? 8.114 56.798 24.031 1.00 63.50 ? 213 GLU L CG 1 ATOM 1688 C CD . GLU A 1 218 ? 7.275 57.030 25.252 1.00 66.67 ? 213 GLU L CD 1 ATOM 1689 O OE1 . GLU A 1 218 ? 6.311 56.289 25.450 1.00 70.57 ? 213 GLU L OE1 1 ATOM 1690 O OE2 . GLU A 1 218 ? 7.613 57.934 26.014 1.00 69.71 ? 213 GLU L OE2 1 ATOM 1691 N N . CYS A 1 219 ? 11.755 57.144 23.488 1.00 83.39 ? 214 CYS L N 1 ATOM 1692 C CA . CYS A 1 219 ? 13.074 57.727 23.652 1.00 87.63 ? 214 CYS L CA 1 ATOM 1693 C C . CYS A 1 219 ? 13.088 59.079 24.375 1.00 87.40 ? 214 CYS L C 1 ATOM 1694 O O . CYS A 1 219 ? 13.862 59.264 25.316 1.00 84.20 ? 214 CYS L O 1 ATOM 1695 C CB . CYS A 1 219 ? 13.646 57.798 22.213 1.00 90.00 ? 214 CYS L CB 1 ATOM 1696 S SG . CYS A 1 219 ? 12.394 57.966 20.885 1.00 88.93 ? 214 CYS L SG 1 ATOM 1697 O OXT . CYS A 1 219 ? 12.298 59.940 23.989 1.00 89.14 ? 214 CYS L OXT 1 ATOM 1698 N N . GLU B 2 1 ? 9.926 9.922 64.703 1.00 64.95 ? 1 GLU H N 1 ATOM 1699 C CA . GLU B 2 1 ? 9.879 10.546 63.398 1.00 66.58 ? 1 GLU H CA 1 ATOM 1700 C C . GLU B 2 1 ? 9.604 9.327 62.525 1.00 60.52 ? 1 GLU H C 1 ATOM 1701 O O . GLU B 2 1 ? 10.306 8.342 62.715 1.00 60.19 ? 1 GLU H O 1 ATOM 1702 C CB . GLU B 2 1 ? 11.254 11.210 63.058 1.00 73.81 ? 1 GLU H CB 1 ATOM 1703 C CG . GLU B 2 1 ? 12.645 10.543 63.376 1.00 84.47 ? 1 GLU H CG 1 ATOM 1704 C CD . GLU B 2 1 ? 13.152 9.289 62.616 1.00 91.43 ? 1 GLU H CD 1 ATOM 1705 O OE1 . GLU B 2 1 ? 12.781 9.056 61.464 1.00 94.99 ? 1 GLU H OE1 1 ATOM 1706 O OE2 . GLU B 2 1 ? 13.941 8.524 63.181 1.00 93.53 ? 1 GLU H OE2 1 ATOM 1707 N N . VAL B 2 2 ? 8.539 9.227 61.752 1.00 49.93 ? 2 VAL H N 1 ATOM 1708 C CA . VAL B 2 2 ? 8.439 8.122 60.821 1.00 38.73 ? 2 VAL H CA 1 ATOM 1709 C C . VAL B 2 2 ? 8.869 8.912 59.601 1.00 36.40 ? 2 VAL H C 1 ATOM 1710 O O . VAL B 2 2 ? 8.640 10.129 59.549 1.00 36.06 ? 2 VAL H O 1 ATOM 1711 C CB . VAL B 2 2 ? 6.978 7.603 60.755 1.00 38.32 ? 2 VAL H CB 1 ATOM 1712 C CG1 . VAL B 2 2 ? 6.675 6.853 59.472 1.00 37.61 ? 2 VAL H CG1 1 ATOM 1713 C CG2 . VAL B 2 2 ? 6.797 6.570 61.870 1.00 33.14 ? 2 VAL H CG2 1 ATOM 1714 N N . GLN B 2 3 ? 9.588 8.279 58.684 1.00 36.16 ? 3 GLN H N 1 ATOM 1715 C CA . GLN B 2 3 ? 10.104 8.949 57.502 1.00 34.97 ? 3 GLN H CA 1 ATOM 1716 C C . GLN B 2 3 ? 9.936 8.020 56.322 1.00 31.12 ? 3 GLN H C 1 ATOM 1717 O O . GLN B 2 3 ? 10.270 6.849 56.501 1.00 38.73 ? 3 GLN H O 1 ATOM 1718 C CB . GLN B 2 3 ? 11.569 9.238 57.662 1.00 39.00 ? 3 GLN H CB 1 ATOM 1719 C CG . GLN B 2 3 ? 11.884 10.662 57.212 1.00 51.21 ? 3 GLN H CG 1 ATOM 1720 C CD . GLN B 2 3 ? 12.419 11.573 58.318 1.00 54.83 ? 3 GLN H CD 1 ATOM 1721 O OE1 . GLN B 2 3 ? 12.431 12.783 58.133 1.00 56.18 ? 3 GLN H OE1 1 ATOM 1722 N NE2 . GLN B 2 3 ? 12.918 11.128 59.475 1.00 52.32 ? 3 GLN H NE2 1 ATOM 1723 N N . LEU B 2 4 ? 9.415 8.386 55.157 1.00 18.69 ? 4 LEU H N 1 ATOM 1724 C CA . LEU B 2 4 ? 9.373 7.456 54.054 1.00 9.73 ? 4 LEU H CA 1 ATOM 1725 C C . LEU B 2 4 ? 10.012 8.296 52.965 1.00 8.59 ? 4 LEU H C 1 ATOM 1726 O O . LEU B 2 4 ? 9.467 9.346 52.642 1.00 17.54 ? 4 LEU H O 1 ATOM 1727 C CB . LEU B 2 4 ? 7.920 7.068 53.708 1.00 12.63 ? 4 LEU H CB 1 ATOM 1728 C CG . LEU B 2 4 ? 7.121 5.993 54.473 1.00 6.60 ? 4 LEU H CG 1 ATOM 1729 C CD1 . LEU B 2 4 ? 7.954 4.735 54.576 1.00 12.00 ? 4 LEU H CD1 1 ATOM 1730 C CD2 . LEU B 2 4 ? 6.869 6.369 55.878 1.00 2.00 ? 4 LEU H CD2 1 ATOM 1731 N N . VAL B 2 5 ? 11.170 7.957 52.402 1.00 8.81 ? 5 VAL H N 1 ATOM 1732 C CA . VAL B 2 5 ? 11.893 8.799 51.455 1.00 7.55 ? 5 VAL H CA 1 ATOM 1733 C C . VAL B 2 5 ? 11.974 7.997 50.154 1.00 11.54 ? 5 VAL H C 1 ATOM 1734 O O . VAL B 2 5 ? 12.545 6.900 50.129 1.00 22.64 ? 5 VAL H O 1 ATOM 1735 C CB . VAL B 2 5 ? 13.275 9.102 52.071 1.00 4.73 ? 5 VAL H CB 1 ATOM 1736 C CG1 . VAL B 2 5 ? 14.052 10.043 51.169 1.00 8.27 ? 5 VAL H CG1 1 ATOM 1737 C CG2 . VAL B 2 5 ? 13.132 9.832 53.390 1.00 8.45 ? 5 VAL H CG2 1 ATOM 1738 N N . GLU B 2 6 ? 11.406 8.472 49.056 1.00 5.16 ? 6 GLU H N 1 ATOM 1739 C CA . GLU B 2 6 ? 11.324 7.704 47.837 1.00 5.67 ? 6 GLU H CA 1 ATOM 1740 C C . GLU B 2 6 ? 12.466 8.146 46.967 1.00 7.31 ? 6 GLU H C 1 ATOM 1741 O O . GLU B 2 6 ? 12.981 9.263 47.132 1.00 13.47 ? 6 GLU H O 1 ATOM 1742 C CB . GLU B 2 6 ? 10.040 7.968 47.083 1.00 10.89 ? 6 GLU H CB 1 ATOM 1743 C CG . GLU B 2 6 ? 8.756 7.620 47.800 1.00 13.68 ? 6 GLU H CG 1 ATOM 1744 C CD . GLU B 2 6 ? 8.199 8.667 48.748 1.00 15.97 ? 6 GLU H CD 1 ATOM 1745 O OE1 . GLU B 2 6 ? 8.934 9.285 49.492 1.00 14.19 ? 6 GLU H OE1 1 ATOM 1746 O OE2 . GLU B 2 6 ? 6.993 8.872 48.770 1.00 20.68 ? 6 GLU H OE2 1 ATOM 1747 N N . SER B 2 7 ? 12.738 7.319 45.970 1.00 4.15 ? 7 SER H N 1 ATOM 1748 C CA . SER B 2 7 ? 13.890 7.477 45.113 1.00 9.41 ? 7 SER H CA 1 ATOM 1749 C C . SER B 2 7 ? 13.560 6.786 43.811 1.00 12.11 ? 7 SER H C 1 ATOM 1750 O O . SER B 2 7 ? 12.813 5.808 43.846 1.00 14.29 ? 7 SER H O 1 ATOM 1751 C CB . SER B 2 7 ? 15.096 6.784 45.720 1.00 15.12 ? 7 SER H CB 1 ATOM 1752 O OG . SER B 2 7 ? 14.980 6.530 47.130 1.00 31.26 ? 7 SER H OG 1 ATOM 1753 N N . GLY B 2 8 ? 13.967 7.244 42.621 1.00 13.78 ? 8 GLY H N 1 ATOM 1754 C CA . GLY B 2 8 ? 13.781 6.406 41.452 1.00 13.02 ? 8 GLY H CA 1 ATOM 1755 C C . GLY B 2 8 ? 13.193 7.011 40.217 1.00 12.17 ? 8 GLY H C 1 ATOM 1756 O O . GLY B 2 8 ? 13.592 6.713 39.089 1.00 18.32 ? 8 GLY H O 1 ATOM 1757 N N . GLY B 2 9 ? 12.190 7.831 40.420 1.00 14.59 ? 9 GLY H N 1 ATOM 1758 C CA . GLY B 2 9 ? 11.514 8.439 39.274 1.00 17.66 ? 9 GLY H CA 1 ATOM 1759 C C . GLY B 2 9 ? 12.439 9.243 38.394 1.00 9.18 ? 9 GLY H C 1 ATOM 1760 O O . GLY B 2 9 ? 13.356 9.866 38.908 1.00 12.44 ? 9 GLY H O 1 ATOM 1761 N N . ASP B 2 10 ? 12.178 9.236 37.105 1.00 9.68 ? 10 ASP H N 1 ATOM 1762 C CA . ASP B 2 10 ? 13.053 9.828 36.121 1.00 7.88 ? 10 ASP H CA 1 ATOM 1763 C C . ASP B 2 10 ? 12.177 9.948 34.884 1.00 7.23 ? 10 ASP H C 1 ATOM 1764 O O . ASP B 2 10 ? 10.987 9.607 34.907 1.00 7.97 ? 10 ASP H O 1 ATOM 1765 C CB . ASP B 2 10 ? 14.185 8.836 35.997 1.00 13.32 ? 10 ASP H CB 1 ATOM 1766 C CG . ASP B 2 10 ? 15.370 9.100 35.080 1.00 23.75 ? 10 ASP H CG 1 ATOM 1767 O OD1 . ASP B 2 10 ? 15.246 8.997 33.865 1.00 32.68 ? 10 ASP H OD1 1 ATOM 1768 O OD2 . ASP B 2 10 ? 16.467 9.329 35.577 1.00 29.72 ? 10 ASP H OD2 1 ATOM 1769 N N . LEU B 2 11 ? 12.693 10.450 33.777 1.00 8.42 ? 11 LEU H N 1 ATOM 1770 C CA . LEU B 2 11 ? 11.919 10.473 32.549 1.00 17.19 ? 11 LEU H CA 1 ATOM 1771 C C . LEU B 2 11 ? 12.175 9.172 31.795 1.00 22.66 ? 11 LEU H C 1 ATOM 1772 O O . LEU B 2 11 ? 13.325 8.754 31.601 1.00 23.72 ? 11 LEU H O 1 ATOM 1773 C CB . LEU B 2 11 ? 12.323 11.641 31.661 1.00 16.65 ? 11 LEU H CB 1 ATOM 1774 C CG . LEU B 2 11 ? 11.735 11.776 30.257 1.00 16.31 ? 11 LEU H CG 1 ATOM 1775 C CD1 . LEU B 2 11 ? 10.229 11.868 30.250 1.00 23.55 ? 11 LEU H CD1 1 ATOM 1776 C CD2 . LEU B 2 11 ? 12.195 13.054 29.683 1.00 20.13 ? 11 LEU H CD2 1 ATOM 1777 N N . VAL B 2 12 ? 11.105 8.514 31.356 1.00 29.01 ? 12 VAL H N 1 ATOM 1778 C CA . VAL B 2 12 ? 11.204 7.261 30.630 1.00 30.38 ? 12 VAL H CA 1 ATOM 1779 C C . VAL B 2 12 ? 10.341 7.389 29.378 1.00 27.68 ? 12 VAL H C 1 ATOM 1780 O O . VAL B 2 12 ? 9.249 7.972 29.367 1.00 21.33 ? 12 VAL H O 1 ATOM 1781 C CB . VAL B 2 12 ? 10.700 6.059 31.530 1.00 33.13 ? 12 VAL H CB 1 ATOM 1782 C CG1 . VAL B 2 12 ? 10.950 4.755 30.803 1.00 34.37 ? 12 VAL H CG1 1 ATOM 1783 C CG2 . VAL B 2 12 ? 11.449 5.960 32.856 1.00 28.96 ? 12 VAL H CG2 1 ATOM 1784 N N . LYS B 2 13 ? 10.870 6.853 28.285 1.00 30.99 ? 13 LYS H N 1 ATOM 1785 C CA . LYS B 2 13 ? 10.120 6.765 27.035 1.00 33.31 ? 13 LYS H CA 1 ATOM 1786 C C . LYS B 2 13 ? 9.053 5.670 27.170 1.00 33.53 ? 13 LYS H C 1 ATOM 1787 O O . LYS B 2 13 ? 9.289 4.640 27.809 1.00 33.36 ? 13 LYS H O 1 ATOM 1788 C CB . LYS B 2 13 ? 11.027 6.408 25.853 1.00 28.86 ? 13 LYS H CB 1 ATOM 1789 C CG . LYS B 2 13 ? 12.145 7.404 25.636 1.00 33.32 ? 13 LYS H CG 1 ATOM 1790 C CD . LYS B 2 13 ? 12.824 7.220 24.286 1.00 38.31 ? 13 LYS H CD 1 ATOM 1791 C CE . LYS B 2 13 ? 11.934 7.742 23.145 1.00 41.35 ? 13 LYS H CE 1 ATOM 1792 N NZ . LYS B 2 13 ? 12.416 8.986 22.562 1.00 39.72 ? 13 LYS H NZ 1 ATOM 1793 N N . PRO B 2 14 ? 7.902 5.804 26.517 1.00 31.59 ? 14 PRO H N 1 ATOM 1794 C CA . PRO B 2 14 ? 6.703 4.998 26.713 1.00 31.47 ? 14 PRO H CA 1 ATOM 1795 C C . PRO B 2 14 ? 6.619 3.469 26.674 1.00 28.89 ? 14 PRO H C 1 ATOM 1796 O O . PRO B 2 14 ? 5.520 2.901 26.706 1.00 32.27 ? 14 PRO H O 1 ATOM 1797 C CB . PRO B 2 14 ? 5.733 5.631 25.740 1.00 33.85 ? 14 PRO H CB 1 ATOM 1798 C CG . PRO B 2 14 ? 6.145 7.065 25.713 1.00 32.23 ? 14 PRO H CG 1 ATOM 1799 C CD . PRO B 2 14 ? 7.632 6.886 25.583 1.00 31.53 ? 14 PRO H CD 1 ATOM 1800 N N . GLY B 2 15 ? 7.686 2.711 26.561 1.00 22.90 ? 15 GLY H N 1 ATOM 1801 C CA . GLY B 2 15 ? 7.558 1.268 26.721 1.00 20.88 ? 15 GLY H CA 1 ATOM 1802 C C . GLY B 2 15 ? 8.506 0.814 27.818 1.00 23.07 ? 15 GLY H C 1 ATOM 1803 O O . GLY B 2 15 ? 8.480 -0.323 28.300 1.00 24.30 ? 15 GLY H O 1 ATOM 1804 N N . GLY B 2 16 ? 9.312 1.774 28.277 1.00 22.16 ? 16 GLY H N 1 ATOM 1805 C CA . GLY B 2 16 ? 10.407 1.515 29.173 1.00 17.59 ? 16 GLY H CA 1 ATOM 1806 C C . GLY B 2 16 ? 9.961 0.968 30.491 1.00 16.54 ? 16 GLY H C 1 ATOM 1807 O O . GLY B 2 16 ? 8.778 0.774 30.820 1.00 16.53 ? 16 GLY H O 1 ATOM 1808 N N . SER B 2 17 ? 11.019 0.723 31.223 1.00 21.54 ? 17 SER H N 1 ATOM 1809 C CA . SER B 2 17 ? 10.822 0.086 32.495 1.00 32.43 ? 17 SER H CA 1 ATOM 1810 C C . SER B 2 17 ? 11.717 0.760 33.500 1.00 32.78 ? 17 SER H C 1 ATOM 1811 O O . SER B 2 17 ? 12.828 1.179 33.138 1.00 34.11 ? 17 SER H O 1 ATOM 1812 C CB . SER B 2 17 ? 11.154 -1.380 32.313 1.00 39.90 ? 17 SER H CB 1 ATOM 1813 O OG . SER B 2 17 ? 10.378 -1.953 31.245 1.00 50.87 ? 17 SER H OG 1 ATOM 1814 N N . LEU B 2 18 ? 11.197 0.854 34.728 1.00 30.13 ? 18 LEU H N 1 ATOM 1815 C CA . LEU B 2 18 ? 11.847 1.569 35.805 1.00 23.64 ? 18 LEU H CA 1 ATOM 1816 C C . LEU B 2 18 ? 11.440 0.919 37.114 1.00 17.76 ? 18 LEU H C 1 ATOM 1817 O O . LEU B 2 18 ? 10.281 0.556 37.308 1.00 13.85 ? 18 LEU H O 1 ATOM 1818 C CB . LEU B 2 18 ? 11.398 3.065 35.800 1.00 24.10 ? 18 LEU H CB 1 ATOM 1819 C CG . LEU B 2 18 ? 12.185 4.176 36.540 1.00 19.49 ? 18 LEU H CG 1 ATOM 1820 C CD1 . LEU B 2 18 ? 13.456 4.564 35.790 1.00 17.16 ? 18 LEU H CD1 1 ATOM 1821 C CD2 . LEU B 2 18 ? 11.315 5.386 36.635 1.00 13.96 ? 18 LEU H CD2 1 ATOM 1822 N N . LYS B 2 19 ? 12.394 0.732 38.012 1.00 18.02 ? 19 LYS H N 1 ATOM 1823 C CA . LYS B 2 19 ? 12.084 0.293 39.355 1.00 18.34 ? 19 LYS H CA 1 ATOM 1824 C C . LYS B 2 19 ? 12.191 1.540 40.270 1.00 19.79 ? 19 LYS H C 1 ATOM 1825 O O . LYS B 2 19 ? 13.227 2.210 40.327 1.00 24.01 ? 19 LYS H O 1 ATOM 1826 C CB . LYS B 2 19 ? 13.078 -0.790 39.734 1.00 20.51 ? 19 LYS H CB 1 ATOM 1827 C CG . LYS B 2 19 ? 13.027 -1.276 41.183 1.00 33.47 ? 19 LYS H CG 1 ATOM 1828 C CD . LYS B 2 19 ? 14.225 -2.166 41.535 1.00 45.05 ? 19 LYS H CD 1 ATOM 1829 C CE . LYS B 2 19 ? 14.238 -3.460 40.682 1.00 54.17 ? 19 LYS H CE 1 ATOM 1830 N NZ . LYS B 2 19 ? 15.377 -4.351 40.903 1.00 55.70 ? 19 LYS H NZ 1 ATOM 1831 N N . LEU B 2 20 ? 11.109 1.970 40.915 1.00 15.54 ? 20 LEU H N 1 ATOM 1832 C CA . LEU B 2 20 ? 11.149 3.048 41.880 1.00 8.89 ? 20 LEU H CA 1 ATOM 1833 C C . LEU B 2 20 ? 11.494 2.383 43.180 1.00 6.61 ? 20 LEU H C 1 ATOM 1834 O O . LEU B 2 20 ? 11.289 1.177 43.307 1.00 9.57 ? 20 LEU H O 1 ATOM 1835 C CB . LEU B 2 20 ? 9.802 3.723 42.086 1.00 9.52 ? 20 LEU H CB 1 ATOM 1836 C CG . LEU B 2 20 ? 9.087 4.405 40.935 1.00 4.21 ? 20 LEU H CG 1 ATOM 1837 C CD1 . LEU B 2 20 ? 8.120 5.420 41.508 1.00 2.00 ? 20 LEU H CD1 1 ATOM 1838 C CD2 . LEU B 2 20 ? 10.049 5.201 40.081 1.00 3.77 ? 20 LEU H CD2 1 ATOM 1839 N N . SER B 2 21 ? 11.909 3.131 44.188 1.00 10.39 ? 21 SER H N 1 ATOM 1840 C CA . SER B 2 21 ? 12.252 2.556 45.475 1.00 13.25 ? 21 SER H CA 1 ATOM 1841 C C . SER B 2 21 ? 11.930 3.493 46.641 1.00 13.03 ? 21 SER H C 1 ATOM 1842 O O . SER B 2 21 ? 11.832 4.703 46.467 1.00 15.87 ? 21 SER H O 1 ATOM 1843 C CB . SER B 2 21 ? 13.735 2.194 45.454 1.00 12.04 ? 21 SER H CB 1 ATOM 1844 O OG . SER B 2 21 ? 14.187 1.729 46.727 1.00 15.48 ? 21 SER H OG 1 ATOM 1845 N N . CYS B 2 22 ? 11.709 2.963 47.834 1.00 13.14 ? 22 CYS H N 1 ATOM 1846 C CA . CYS B 2 22 ? 11.360 3.733 49.000 1.00 11.83 ? 22 CYS H CA 1 ATOM 1847 C C . CYS B 2 22 ? 12.133 3.129 50.149 1.00 17.00 ? 22 CYS H C 1 ATOM 1848 O O . CYS B 2 22 ? 12.372 1.914 50.152 1.00 22.80 ? 22 CYS H O 1 ATOM 1849 C CB . CYS B 2 22 ? 9.897 3.611 49.302 1.00 12.75 ? 22 CYS H CB 1 ATOM 1850 S SG . CYS B 2 22 ? 9.533 4.067 51.021 1.00 22.61 ? 22 CYS H SG 1 ATOM 1851 N N . ALA B 2 23 ? 12.555 3.920 51.136 1.00 16.71 ? 23 ALA H N 1 ATOM 1852 C CA . ALA B 2 23 ? 13.245 3.387 52.298 1.00 13.42 ? 23 ALA H CA 1 ATOM 1853 C C . ALA B 2 23 ? 12.552 3.913 53.535 1.00 10.81 ? 23 ALA H C 1 ATOM 1854 O O . ALA B 2 23 ? 12.199 5.086 53.558 1.00 9.37 ? 23 ALA H O 1 ATOM 1855 C CB . ALA B 2 23 ? 14.691 3.842 52.321 1.00 10.08 ? 23 ALA H CB 1 ATOM 1856 N N . ALA B 2 24 ? 12.341 3.114 54.557 1.00 8.47 ? 24 ALA H N 1 ATOM 1857 C CA . ALA B 2 24 ? 11.604 3.594 55.689 1.00 13.79 ? 24 ALA H CA 1 ATOM 1858 C C . ALA B 2 24 ? 12.446 3.652 56.948 1.00 19.71 ? 24 ALA H C 1 ATOM 1859 O O . ALA B 2 24 ? 13.517 3.038 57.010 1.00 22.64 ? 24 ALA H O 1 ATOM 1860 C CB . ALA B 2 24 ? 10.438 2.686 55.895 1.00 14.10 ? 24 ALA H CB 1 ATOM 1861 N N . SER B 2 25 ? 11.962 4.407 57.934 1.00 23.02 ? 25 SER H N 1 ATOM 1862 C CA . SER B 2 25 ? 12.646 4.600 59.195 1.00 30.00 ? 25 SER H CA 1 ATOM 1863 C C . SER B 2 25 ? 11.785 5.201 60.289 1.00 28.60 ? 25 SER H C 1 ATOM 1864 O O . SER B 2 25 ? 10.754 5.844 60.068 1.00 31.64 ? 25 SER H O 1 ATOM 1865 C CB . SER B 2 25 ? 13.854 5.496 59.015 1.00 35.05 ? 25 SER H CB 1 ATOM 1866 O OG . SER B 2 25 ? 14.962 4.623 59.208 1.00 47.22 ? 25 SER H OG 1 ATOM 1867 N N . GLY B 2 26 ? 12.182 4.932 61.512 1.00 20.61 ? 26 GLY H N 1 ATOM 1868 C CA . GLY B 2 26 ? 11.422 5.453 62.606 1.00 22.52 ? 26 GLY H CA 1 ATOM 1869 C C . GLY B 2 26 ? 10.419 4.461 63.115 1.00 20.83 ? 26 GLY H C 1 ATOM 1870 O O . GLY B 2 26 ? 10.071 4.530 64.296 1.00 28.42 ? 26 GLY H O 1 ATOM 1871 N N . PHE B 2 27 ? 9.975 3.514 62.304 1.00 17.68 ? 27 PHE H N 1 ATOM 1872 C CA . PHE B 2 27 ? 9.014 2.541 62.793 1.00 21.73 ? 27 PHE H CA 1 ATOM 1873 C C . PHE B 2 27 ? 9.519 1.126 62.619 1.00 26.90 ? 27 PHE H C 1 ATOM 1874 O O . PHE B 2 27 ? 10.551 0.867 61.994 1.00 33.47 ? 27 PHE H O 1 ATOM 1875 C CB . PHE B 2 27 ? 7.658 2.702 62.067 1.00 16.27 ? 27 PHE H CB 1 ATOM 1876 C CG . PHE B 2 27 ? 7.684 2.590 60.560 1.00 10.83 ? 27 PHE H CG 1 ATOM 1877 C CD1 . PHE B 2 27 ? 8.093 3.651 59.792 1.00 12.77 ? 27 PHE H CD1 1 ATOM 1878 C CD2 . PHE B 2 27 ? 7.322 1.417 59.968 1.00 6.55 ? 27 PHE H CD2 1 ATOM 1879 C CE1 . PHE B 2 27 ? 8.147 3.537 58.424 1.00 11.12 ? 27 PHE H CE1 1 ATOM 1880 C CE2 . PHE B 2 27 ? 7.380 1.319 58.604 1.00 7.42 ? 27 PHE H CE2 1 ATOM 1881 C CZ . PHE B 2 27 ? 7.789 2.367 57.828 1.00 7.77 ? 27 PHE H CZ 1 ATOM 1882 N N . THR B 2 28 ? 8.756 0.190 63.155 1.00 31.15 ? 28 THR H N 1 ATOM 1883 C CA . THR B 2 28 ? 9.057 -1.232 63.124 1.00 29.06 ? 28 THR H CA 1 ATOM 1884 C C . THR B 2 28 ? 8.639 -1.789 61.768 1.00 23.18 ? 28 THR H C 1 ATOM 1885 O O . THR B 2 28 ? 7.585 -2.422 61.685 1.00 18.23 ? 28 THR H O 1 ATOM 1886 C CB . THR B 2 28 ? 8.263 -1.859 64.269 1.00 35.21 ? 28 THR H CB 1 ATOM 1887 O OG1 . THR B 2 28 ? 7.929 -0.891 65.294 1.00 44.99 ? 28 THR H OG1 1 ATOM 1888 C CG2 . THR B 2 28 ? 9.095 -3.005 64.776 1.00 37.05 ? 28 THR H CG2 1 ATOM 1889 N N . PHE B 2 29 ? 9.440 -1.655 60.712 1.00 22.64 ? 29 PHE H N 1 ATOM 1890 C CA . PHE B 2 29 ? 9.003 -1.934 59.336 1.00 22.51 ? 29 PHE H CA 1 ATOM 1891 C C . PHE B 2 29 ? 8.076 -3.116 59.083 1.00 25.30 ? 29 PHE H C 1 ATOM 1892 O O . PHE B 2 29 ? 6.982 -2.943 58.561 1.00 29.83 ? 29 PHE H O 1 ATOM 1893 C CB . PHE B 2 29 ? 10.253 -2.057 58.461 1.00 19.69 ? 29 PHE H CB 1 ATOM 1894 C CG . PHE B 2 29 ? 10.047 -1.922 56.956 1.00 22.73 ? 29 PHE H CG 1 ATOM 1895 C CD1 . PHE B 2 29 ? 9.396 -0.841 56.406 1.00 26.36 ? 29 PHE H CD1 1 ATOM 1896 C CD2 . PHE B 2 29 ? 10.552 -2.880 56.094 1.00 25.43 ? 29 PHE H CD2 1 ATOM 1897 C CE1 . PHE B 2 29 ? 9.264 -0.733 55.023 1.00 26.49 ? 29 PHE H CE1 1 ATOM 1898 C CE2 . PHE B 2 29 ? 10.419 -2.764 54.718 1.00 23.67 ? 29 PHE H CE2 1 ATOM 1899 C CZ . PHE B 2 29 ? 9.772 -1.686 54.172 1.00 19.98 ? 29 PHE H CZ 1 ATOM 1900 N N . SER B 2 30 ? 8.409 -4.288 59.599 1.00 27.83 ? 30 SER H N 1 ATOM 1901 C CA . SER B 2 30 ? 7.658 -5.505 59.334 1.00 28.74 ? 30 SER H CA 1 ATOM 1902 C C . SER B 2 30 ? 6.285 -5.479 59.973 1.00 26.41 ? 30 SER H C 1 ATOM 1903 O O . SER B 2 30 ? 5.314 -5.942 59.402 1.00 24.25 ? 30 SER H O 1 ATOM 1904 C CB . SER B 2 30 ? 8.471 -6.675 59.850 1.00 30.76 ? 30 SER H CB 1 ATOM 1905 O OG . SER B 2 30 ? 9.841 -6.283 60.103 1.00 34.16 ? 30 SER H OG 1 ATOM 1906 N N . ARG B 2 31 ? 6.104 -4.863 61.130 1.00 27.43 ? 31 ARG H N 1 ATOM 1907 C CA . ARG B 2 31 ? 4.794 -4.861 61.741 1.00 34.59 ? 31 ARG H CA 1 ATOM 1908 C C . ARG B 2 31 ? 3.848 -4.139 60.831 1.00 34.36 ? 31 ARG H C 1 ATOM 1909 O O . ARG B 2 31 ? 2.652 -4.382 60.892 1.00 43.31 ? 31 ARG H O 1 ATOM 1910 C CB . ARG B 2 31 ? 4.712 -4.109 63.059 1.00 46.77 ? 31 ARG H CB 1 ATOM 1911 C CG . ARG B 2 31 ? 5.643 -4.616 64.144 1.00 59.47 ? 31 ARG H CG 1 ATOM 1912 C CD . ARG B 2 31 ? 5.075 -4.374 65.543 1.00 70.18 ? 31 ARG H CD 1 ATOM 1913 N NE . ARG B 2 31 ? 4.986 -5.684 66.180 1.00 83.93 ? 31 ARG H NE 1 ATOM 1914 C CZ . ARG B 2 31 ? 3.900 -6.484 66.109 1.00 91.75 ? 31 ARG H CZ 1 ATOM 1915 N NH1 . ARG B 2 31 ? 2.734 -6.091 65.569 1.00 95.93 ? 31 ARG H NH1 1 ATOM 1916 N NH2 . ARG B 2 31 ? 3.965 -7.709 66.645 1.00 94.42 ? 31 ARG H NH2 1 ATOM 1917 N N . CYS B 2 32 ? 4.373 -3.319 59.927 1.00 27.75 ? 32 CYS H N 1 ATOM 1918 C CA . CYS B 2 32 ? 3.549 -2.434 59.185 1.00 17.59 ? 32 CYS H CA 1 ATOM 1919 C C . CYS B 2 32 ? 3.517 -2.770 57.701 1.00 15.00 ? 32 CYS H C 1 ATOM 1920 O O . CYS B 2 32 ? 4.530 -3.109 57.099 1.00 10.22 ? 32 CYS H O 1 ATOM 1921 C CB . CYS B 2 32 ? 4.132 -1.095 59.596 1.00 10.77 ? 32 CYS H CB 1 ATOM 1922 S SG . CYS B 2 32 ? 3.333 -0.544 61.126 1.00 28.90 ? 32 CYS H SG 1 ATOM 1923 N N . ALA B 2 33 ? 2.305 -2.740 57.127 1.00 13.29 ? 33 ALA H N 1 ATOM 1924 C CA . ALA B 2 33 ? 2.060 -3.015 55.710 1.00 5.51 ? 33 ALA H CA 1 ATOM 1925 C C . ALA B 2 33 ? 2.334 -1.789 54.877 1.00 12.39 ? 33 ALA H C 1 ATOM 1926 O O . ALA B 2 33 ? 2.136 -0.679 55.374 1.00 19.15 ? 33 ALA H O 1 ATOM 1927 C CB . ALA B 2 33 ? 0.625 -3.350 55.479 1.00 2.61 ? 33 ALA H CB 1 ATOM 1928 N N . MET B 2 34 ? 2.628 -1.899 53.593 1.00 15.15 ? 34 MET H N 1 ATOM 1929 C CA . MET B 2 34 ? 2.992 -0.738 52.795 1.00 10.86 ? 34 MET H CA 1 ATOM 1930 C C . MET B 2 34 ? 2.225 -0.563 51.486 1.00 12.40 ? 34 MET H C 1 ATOM 1931 O O . MET B 2 34 ? 1.541 -1.484 51.019 1.00 14.53 ? 34 MET H O 1 ATOM 1932 C CB . MET B 2 34 ? 4.457 -0.834 52.482 1.00 11.25 ? 34 MET H CB 1 ATOM 1933 C CG . MET B 2 34 ? 5.375 -0.586 53.650 1.00 16.81 ? 34 MET H CG 1 ATOM 1934 S SD . MET B 2 34 ? 5.341 1.085 54.351 1.00 12.68 ? 34 MET H SD 1 ATOM 1935 C CE . MET B 2 34 ? 5.533 0.276 55.898 1.00 4.53 ? 34 MET H CE 1 ATOM 1936 N N . SER B 2 35 ? 2.418 0.578 50.813 1.00 13.90 ? 35 SER H N 1 ATOM 1937 C CA . SER B 2 35 ? 1.738 0.905 49.588 1.00 9.08 ? 35 SER H CA 1 ATOM 1938 C C . SER B 2 35 ? 2.452 1.884 48.685 1.00 6.19 ? 35 SER H C 1 ATOM 1939 O O . SER B 2 35 ? 3.364 2.588 49.114 1.00 13.31 ? 35 SER H O 1 ATOM 1940 C CB . SER B 2 35 ? 0.410 1.489 49.908 1.00 12.37 ? 35 SER H CB 1 ATOM 1941 O OG . SER B 2 35 ? -0.348 1.115 48.772 1.00 21.46 ? 35 SER H OG 1 ATOM 1942 N N . TRP B 2 36 ? 2.080 1.899 47.427 1.00 2.00 ? 36 TRP H N 1 ATOM 1943 C CA . TRP B 2 36 ? 2.501 2.966 46.574 1.00 2.28 ? 36 TRP H CA 1 ATOM 1944 C C . TRP B 2 36 ? 1.177 3.569 46.108 1.00 10.80 ? 36 TRP H C 1 ATOM 1945 O O . TRP B 2 36 ? 0.247 2.807 45.791 1.00 16.71 ? 36 TRP H O 1 ATOM 1946 C CB . TRP B 2 36 ? 3.268 2.434 45.418 1.00 6.75 ? 36 TRP H CB 1 ATOM 1947 C CG . TRP B 2 36 ? 4.723 2.116 45.734 1.00 15.41 ? 36 TRP H CG 1 ATOM 1948 C CD1 . TRP B 2 36 ? 5.116 0.848 46.059 1.00 16.30 ? 36 TRP H CD1 1 ATOM 1949 C CD2 . TRP B 2 36 ? 5.767 3.022 45.748 1.00 19.49 ? 36 TRP H CD2 1 ATOM 1950 N NE1 . TRP B 2 36 ? 6.402 0.947 46.289 1.00 20.06 ? 36 TRP H NE1 1 ATOM 1951 C CE2 . TRP B 2 36 ? 6.832 2.214 46.121 1.00 18.34 ? 36 TRP H CE2 1 ATOM 1952 C CE3 . TRP B 2 36 ? 5.957 4.385 45.510 1.00 19.14 ? 36 TRP H CE3 1 ATOM 1953 C CZ2 . TRP B 2 36 ? 8.096 2.766 46.259 1.00 19.11 ? 36 TRP H CZ2 1 ATOM 1954 C CZ3 . TRP B 2 36 ? 7.220 4.928 45.650 1.00 14.55 ? 36 TRP H CZ3 1 ATOM 1955 C CH2 . TRP B 2 36 ? 8.279 4.122 46.020 1.00 16.52 ? 36 TRP H CH2 1 ATOM 1956 N N . VAL B 2 37 ? 0.996 4.893 46.085 1.00 8.21 ? 37 VAL H N 1 ATOM 1957 C CA . VAL B 2 37 ? -0.196 5.579 45.583 1.00 5.68 ? 37 VAL H CA 1 ATOM 1958 C C . VAL B 2 37 ? 0.351 6.771 44.761 1.00 10.58 ? 37 VAL H C 1 ATOM 1959 O O . VAL B 2 37 ? 1.438 7.297 45.033 1.00 6.73 ? 37 VAL H O 1 ATOM 1960 C CB . VAL B 2 37 ? -1.086 5.976 46.814 1.00 5.14 ? 37 VAL H CB 1 ATOM 1961 C CG1 . VAL B 2 37 ? -0.261 6.672 47.830 1.00 14.20 ? 37 VAL H CG1 1 ATOM 1962 C CG2 . VAL B 2 37 ? -2.153 6.974 46.464 1.00 4.32 ? 37 VAL H CG2 1 ATOM 1963 N N . ARG B 2 38 ? -0.300 7.167 43.663 1.00 14.14 ? 38 ARG H N 1 ATOM 1964 C CA . ARG B 2 38 ? 0.216 8.166 42.719 1.00 13.97 ? 38 ARG H CA 1 ATOM 1965 C C . ARG B 2 38 ? -0.753 9.325 42.626 1.00 18.30 ? 38 ARG H C 1 ATOM 1966 O O . ARG B 2 38 ? -1.967 9.153 42.799 1.00 23.59 ? 38 ARG H O 1 ATOM 1967 C CB . ARG B 2 38 ? 0.408 7.599 41.281 1.00 5.79 ? 38 ARG H CB 1 ATOM 1968 C CG . ARG B 2 38 ? -0.720 6.692 40.939 1.00 6.69 ? 38 ARG H CG 1 ATOM 1969 C CD . ARG B 2 38 ? -1.199 6.802 39.548 1.00 10.52 ? 38 ARG H CD 1 ATOM 1970 N NE . ARG B 2 38 ? -0.481 5.854 38.744 1.00 19.99 ? 38 ARG H NE 1 ATOM 1971 C CZ . ARG B 2 38 ? -1.060 5.174 37.751 1.00 20.14 ? 38 ARG H CZ 1 ATOM 1972 N NH1 . ARG B 2 38 ? -2.336 5.287 37.410 1.00 18.60 ? 38 ARG H NH1 1 ATOM 1973 N NH2 . ARG B 2 38 ? -0.307 4.349 37.057 1.00 21.80 ? 38 ARG H NH2 1 ATOM 1974 N N . GLN B 2 39 ? -0.235 10.520 42.389 1.00 13.94 ? 39 GLN H N 1 ATOM 1975 C CA . GLN B 2 39 ? -1.085 11.675 42.248 1.00 8.84 ? 39 GLN H CA 1 ATOM 1976 C C . GLN B 2 39 ? -0.841 12.132 40.830 1.00 8.95 ? 39 GLN H C 1 ATOM 1977 O O . GLN B 2 39 ? 0.314 12.376 40.459 1.00 15.70 ? 39 GLN H O 1 ATOM 1978 C CB . GLN B 2 39 ? -0.625 12.645 43.264 1.00 9.43 ? 39 GLN H CB 1 ATOM 1979 C CG . GLN B 2 39 ? -1.551 13.820 43.316 1.00 14.54 ? 39 GLN H CG 1 ATOM 1980 C CD . GLN B 2 39 ? -1.441 14.558 44.633 1.00 12.47 ? 39 GLN H CD 1 ATOM 1981 O OE1 . GLN B 2 39 ? -0.350 14.697 45.201 1.00 11.49 ? 39 GLN H OE1 1 ATOM 1982 N NE2 . GLN B 2 39 ? -2.568 15.033 45.148 1.00 5.53 ? 39 GLN H NE2 1 ATOM 1983 N N . THR B 2 40 ? -1.827 12.184 39.963 1.00 6.80 ? 40 THR H N 1 ATOM 1984 C CA . THR B 2 40 ? -1.537 12.562 38.597 1.00 11.94 ? 40 THR H CA 1 ATOM 1985 C C . THR B 2 40 ? -1.519 14.071 38.410 1.00 19.85 ? 40 THR H C 1 ATOM 1986 O O . THR B 2 40 ? -1.994 14.770 39.297 1.00 18.99 ? 40 THR H O 1 ATOM 1987 C CB . THR B 2 40 ? -2.599 11.929 37.675 1.00 16.02 ? 40 THR H CB 1 ATOM 1988 O OG1 . THR B 2 40 ? -3.943 12.235 38.095 1.00 16.64 ? 40 THR H OG1 1 ATOM 1989 C CG2 . THR B 2 40 ? -2.345 10.466 37.649 1.00 19.19 ? 40 THR H CG2 1 ATOM 1990 N N . PRO B 2 41 ? -1.158 14.604 37.235 1.00 25.66 ? 41 PRO H N 1 ATOM 1991 C CA . PRO B 2 41 ? -1.770 15.751 36.581 1.00 26.91 ? 41 PRO H CA 1 ATOM 1992 C C . PRO B 2 41 ? -2.967 16.444 37.195 1.00 34.05 ? 41 PRO H C 1 ATOM 1993 O O . PRO B 2 41 ? -2.629 17.385 37.898 1.00 35.76 ? 41 PRO H O 1 ATOM 1994 C CB . PRO B 2 41 ? -2.027 15.217 35.206 1.00 29.36 ? 41 PRO H CB 1 ATOM 1995 C CG . PRO B 2 41 ? -0.681 14.592 34.956 1.00 29.25 ? 41 PRO H CG 1 ATOM 1996 C CD . PRO B 2 41 ? -0.253 13.977 36.289 1.00 27.76 ? 41 PRO H CD 1 ATOM 1997 N N . GLU B 2 42 ? -4.300 16.170 37.073 1.00 41.35 ? 42 GLU H N 1 ATOM 1998 C CA . GLU B 2 42 ? -5.267 17.015 37.810 1.00 44.61 ? 42 GLU H CA 1 ATOM 1999 C C . GLU B 2 42 ? -5.516 16.507 39.220 1.00 36.47 ? 42 GLU H C 1 ATOM 2000 O O . GLU B 2 42 ? -6.628 16.158 39.606 1.00 36.85 ? 42 GLU H O 1 ATOM 2001 C CB . GLU B 2 42 ? -6.653 17.143 37.074 1.00 53.54 ? 42 GLU H CB 1 ATOM 2002 C CG . GLU B 2 42 ? -7.722 18.161 37.658 1.00 62.20 ? 42 GLU H CG 1 ATOM 2003 C CD . GLU B 2 42 ? -7.376 19.659 37.896 1.00 69.10 ? 42 GLU H CD 1 ATOM 2004 O OE1 . GLU B 2 42 ? -6.504 20.233 37.225 1.00 70.20 ? 42 GLU H OE1 1 ATOM 2005 O OE2 . GLU B 2 42 ? -8.007 20.275 38.768 1.00 69.26 ? 42 GLU H OE2 1 ATOM 2006 N N . LYS B 2 43 ? -4.418 16.419 39.962 1.00 32.50 ? 43 LYS H N 1 ATOM 2007 C CA . LYS B 2 43 ? -4.359 15.996 41.348 1.00 34.63 ? 43 LYS H CA 1 ATOM 2008 C C . LYS B 2 43 ? -5.190 14.815 41.820 1.00 29.82 ? 43 LYS H C 1 ATOM 2009 O O . LYS B 2 43 ? -5.346 14.662 43.020 1.00 28.15 ? 43 LYS H O 1 ATOM 2010 C CB . LYS B 2 43 ? -4.659 17.207 42.243 1.00 41.17 ? 43 LYS H CB 1 ATOM 2011 C CG . LYS B 2 43 ? -3.479 18.200 42.255 1.00 50.72 ? 43 LYS H CG 1 ATOM 2012 C CD . LYS B 2 43 ? -3.464 19.191 43.452 1.00 58.86 ? 43 LYS H CD 1 ATOM 2013 C CE . LYS B 2 43 ? -3.541 18.500 44.840 1.00 59.27 ? 43 LYS H CE 1 ATOM 2014 N NZ . LYS B 2 43 ? -3.097 19.332 45.945 1.00 56.36 ? 43 LYS H NZ 1 ATOM 2015 N N . ARG B 2 44 ? -5.660 13.930 40.932 1.00 26.31 ? 44 ARG H N 1 ATOM 2016 C CA . ARG B 2 44 ? -6.413 12.765 41.322 1.00 23.54 ? 44 ARG H CA 1 ATOM 2017 C C . ARG B 2 44 ? -5.418 11.787 41.943 1.00 20.84 ? 44 ARG H C 1 ATOM 2018 O O . ARG B 2 44 ? -4.283 11.628 41.474 1.00 25.56 ? 44 ARG H O 1 ATOM 2019 C CB . ARG B 2 44 ? -7.116 12.202 40.069 1.00 30.72 ? 44 ARG H CB 1 ATOM 2020 C CG . ARG B 2 44 ? -8.630 12.602 40.067 1.00 47.11 ? 44 ARG H CG 1 ATOM 2021 C CD . ARG B 2 44 ? -9.645 12.023 39.000 1.00 61.05 ? 44 ARG H CD 1 ATOM 2022 N NE . ARG B 2 44 ? -9.793 10.551 38.925 1.00 70.31 ? 44 ARG H NE 1 ATOM 2023 C CZ . ARG B 2 44 ? -10.471 9.865 37.964 1.00 69.59 ? 44 ARG H CZ 1 ATOM 2024 N NH1 . ARG B 2 44 ? -11.167 10.464 36.982 1.00 67.99 ? 44 ARG H NH1 1 ATOM 2025 N NH2 . ARG B 2 44 ? -10.464 8.521 37.997 1.00 65.76 ? 44 ARG H NH2 1 ATOM 2026 N N . LEU B 2 45 ? -5.779 11.190 43.065 1.00 11.83 ? 45 LEU H N 1 ATOM 2027 C CA . LEU B 2 45 ? -4.902 10.262 43.758 1.00 15.99 ? 45 LEU H CA 1 ATOM 2028 C C . LEU B 2 45 ? -5.232 8.794 43.480 1.00 21.38 ? 45 LEU H C 1 ATOM 2029 O O . LEU B 2 45 ? -6.263 8.342 43.974 1.00 31.41 ? 45 LEU H O 1 ATOM 2030 C CB . LEU B 2 45 ? -4.995 10.475 45.260 1.00 6.65 ? 45 LEU H CB 1 ATOM 2031 C CG . LEU B 2 45 ? -4.388 11.647 45.985 1.00 4.89 ? 45 LEU H CG 1 ATOM 2032 C CD1 . LEU B 2 45 ? -4.982 11.644 47.385 1.00 2.00 ? 45 LEU H CD1 1 ATOM 2033 C CD2 . LEU B 2 45 ? -2.864 11.546 46.069 1.00 2.99 ? 45 LEU H CD2 1 ATOM 2034 N N . GLU B 2 46 ? -4.488 7.960 42.749 1.00 24.34 ? 46 GLU H N 1 ATOM 2035 C CA . GLU B 2 46 ? -4.830 6.545 42.579 1.00 22.77 ? 46 GLU H CA 1 ATOM 2036 C C . GLU B 2 46 ? -4.051 5.627 43.502 1.00 21.46 ? 46 GLU H C 1 ATOM 2037 O O . GLU B 2 46 ? -2.847 5.852 43.634 1.00 19.18 ? 46 GLU H O 1 ATOM 2038 C CB . GLU B 2 46 ? -4.530 6.055 41.212 1.00 21.20 ? 46 GLU H CB 1 ATOM 2039 C CG . GLU B 2 46 ? -5.412 6.639 40.163 1.00 31.89 ? 46 GLU H CG 1 ATOM 2040 C CD . GLU B 2 46 ? -5.136 6.066 38.778 1.00 39.37 ? 46 GLU H CD 1 ATOM 2041 O OE1 . GLU B 2 46 ? -4.895 4.853 38.646 1.00 41.13 ? 46 GLU H OE1 1 ATOM 2042 O OE2 . GLU B 2 46 ? -5.183 6.856 37.827 1.00 42.86 ? 46 GLU H OE2 1 ATOM 2043 N N . TRP B 2 47 ? -4.624 4.628 44.191 1.00 21.57 ? 47 TRP H N 1 ATOM 2044 C CA . TRP B 2 47 ? -3.801 3.640 44.901 1.00 23.61 ? 47 TRP H CA 1 ATOM 2045 C C . TRP B 2 47 ? -3.216 2.776 43.800 1.00 25.82 ? 47 TRP H C 1 ATOM 2046 O O . TRP B 2 47 ? -3.879 2.528 42.783 1.00 24.93 ? 47 TRP H O 1 ATOM 2047 C CB . TRP B 2 47 ? -4.616 2.743 45.814 1.00 23.78 ? 47 TRP H CB 1 ATOM 2048 C CG . TRP B 2 47 ? -4.013 1.449 46.375 1.00 21.66 ? 47 TRP H CG 1 ATOM 2049 C CD1 . TRP B 2 47 ? -3.098 1.480 47.371 1.00 22.52 ? 47 TRP H CD1 1 ATOM 2050 C CD2 . TRP B 2 47 ? -4.383 0.160 46.055 1.00 22.21 ? 47 TRP H CD2 1 ATOM 2051 N NE1 . TRP B 2 47 ? -2.910 0.232 47.705 1.00 22.00 ? 47 TRP H NE1 1 ATOM 2052 C CE2 . TRP B 2 47 ? -3.646 -0.580 46.948 1.00 22.07 ? 47 TRP H CE2 1 ATOM 2053 C CE3 . TRP B 2 47 ? -5.230 -0.495 45.176 1.00 19.67 ? 47 TRP H CE3 1 ATOM 2054 C CZ2 . TRP B 2 47 ? -3.750 -1.957 46.964 1.00 24.33 ? 47 TRP H CZ2 1 ATOM 2055 C CZ3 . TRP B 2 47 ? -5.341 -1.872 45.185 1.00 13.75 ? 47 TRP H CZ3 1 ATOM 2056 C CH2 . TRP B 2 47 ? -4.604 -2.600 46.075 1.00 18.40 ? 47 TRP H CH2 1 ATOM 2057 N N . VAL B 2 48 ? -1.979 2.339 43.970 1.00 22.86 ? 48 VAL H N 1 ATOM 2058 C CA . VAL B 2 48 ? -1.437 1.527 42.931 1.00 16.37 ? 48 VAL H CA 1 ATOM 2059 C C . VAL B 2 48 ? -0.885 0.205 43.453 1.00 20.16 ? 48 VAL H C 1 ATOM 2060 O O . VAL B 2 48 ? -0.857 -0.710 42.643 1.00 23.75 ? 48 VAL H O 1 ATOM 2061 C CB . VAL B 2 48 ? -0.440 2.461 42.189 1.00 9.56 ? 48 VAL H CB 1 ATOM 2062 C CG1 . VAL B 2 48 ? 0.817 2.825 42.891 1.00 9.57 ? 48 VAL H CG1 1 ATOM 2063 C CG2 . VAL B 2 48 ? 0.036 1.679 41.025 1.00 18.64 ? 48 VAL H CG2 1 ATOM 2064 N N . ALA B 2 49 ? -0.497 -0.087 44.699 1.00 20.47 ? 49 ALA H N 1 ATOM 2065 C CA . ALA B 2 49 ? -0.020 -1.436 45.043 1.00 20.43 ? 49 ALA H CA 1 ATOM 2066 C C . ALA B 2 49 ? 0.099 -1.633 46.537 1.00 21.03 ? 49 ALA H C 1 ATOM 2067 O O . ALA B 2 49 ? 0.774 -0.852 47.219 1.00 22.53 ? 49 ALA H O 1 ATOM 2068 C CB . ALA B 2 49 ? 1.378 -1.752 44.485 1.00 14.50 ? 49 ALA H CB 1 ATOM 2069 N N . GLY B 2 50 ? -0.556 -2.628 47.102 1.00 20.45 ? 50 GLY H N 1 ATOM 2070 C CA . GLY B 2 50 ? -0.452 -2.842 48.535 1.00 18.85 ? 50 GLY H CA 1 ATOM 2071 C C . GLY B 2 50 ? 0.288 -4.139 48.756 1.00 16.46 ? 50 GLY H C 1 ATOM 2072 O O . GLY B 2 50 ? 0.183 -5.041 47.908 1.00 12.00 ? 50 GLY H O 1 ATOM 2073 N N . ILE B 2 51 ? 1.062 -4.264 49.822 1.00 11.02 ? 51 ILE H N 1 ATOM 2074 C CA . ILE B 2 51 ? 1.687 -5.543 50.091 1.00 11.54 ? 51 ILE H CA 1 ATOM 2075 C C . ILE B 2 51 ? 1.613 -5.639 51.587 1.00 15.43 ? 51 ILE H C 1 ATOM 2076 O O . ILE B 2 51 ? 1.699 -4.631 52.319 1.00 11.88 ? 51 ILE H O 1 ATOM 2077 C CB . ILE B 2 51 ? 3.173 -5.632 49.634 1.00 10.13 ? 51 ILE H CB 1 ATOM 2078 C CG1 . ILE B 2 51 ? 3.697 -7.023 49.926 1.00 7.58 ? 51 ILE H CG1 1 ATOM 2079 C CG2 . ILE B 2 51 ? 4.052 -4.622 50.381 1.00 11.30 ? 51 ILE H CG2 1 ATOM 2080 C CD1 . ILE B 2 51 ? 4.971 -7.324 49.134 1.00 13.82 ? 51 ILE H CD1 1 ATOM 2081 N N . SER B 2 52 ? 1.382 -6.903 51.935 1.00 21.62 ? 52 SER H N 1 ATOM 2082 C CA . SER B 2 52 ? 1.224 -7.348 53.304 1.00 26.71 ? 52 SER H CA 1 ATOM 2083 C C . SER B 2 52 ? 2.491 -7.129 54.085 1.00 24.45 ? 52 SER H C 1 ATOM 2084 O O . SER B 2 52 ? 3.548 -6.964 53.473 1.00 28.52 ? 52 SER H O 1 ATOM 2085 C CB . SER B 2 52 ? 0.876 -8.825 53.301 1.00 30.86 ? 52 SER H CB 1 ATOM 2086 O OG . SER B 2 52 ? 1.877 -9.679 52.739 1.00 35.00 ? 52 SER H OG 1 ATOM 2087 N N . SER B 2 53 A 2.439 -7.215 55.409 1.00 24.29 ? 52 SER H N 1 ATOM 2088 C CA . SER B 2 53 A 3.654 -7.088 56.214 1.00 24.85 ? 52 SER H CA 1 ATOM 2089 C C . SER B 2 53 A 4.697 -8.145 55.920 1.00 24.89 ? 52 SER H C 1 ATOM 2090 O O . SER B 2 53 A 5.882 -7.896 56.092 1.00 30.26 ? 52 SER H O 1 ATOM 2091 C CB . SER B 2 53 A 3.344 -7.205 57.671 1.00 20.93 ? 52 SER H CB 1 ATOM 2092 O OG . SER B 2 53 A 2.337 -6.290 58.023 1.00 24.39 ? 52 SER H OG 1 ATOM 2093 N N . GLY B 2 54 ? 4.263 -9.355 55.539 1.00 21.38 ? 53 GLY H N 1 ATOM 2094 C CA . GLY B 2 54 ? 5.206 -10.412 55.278 1.00 17.67 ? 53 GLY H CA 1 ATOM 2095 C C . GLY B 2 54 ? 5.419 -10.573 53.796 1.00 17.91 ? 53 GLY H C 1 ATOM 2096 O O . GLY B 2 54 ? 5.947 -11.590 53.390 1.00 18.00 ? 53 GLY H O 1 ATOM 2097 N N . GLY B 2 55 ? 4.950 -9.695 52.923 1.00 22.66 ? 54 GLY H N 1 ATOM 2098 C CA . GLY B 2 55 ? 5.199 -9.837 51.505 1.00 21.80 ? 54 GLY H CA 1 ATOM 2099 C C . GLY B 2 55 ? 4.567 -11.078 50.942 1.00 23.03 ? 54 GLY H C 1 ATOM 2100 O O . GLY B 2 55 ? 4.919 -11.518 49.857 1.00 29.75 ? 54 GLY H O 1 ATOM 2101 N N . SER B 2 56 ? 3.626 -11.637 51.701 1.00 23.80 ? 55 SER H N 1 ATOM 2102 C CA . SER B 2 56 ? 2.905 -12.870 51.376 1.00 22.37 ? 55 SER H CA 1 ATOM 2103 C C . SER B 2 56 ? 1.782 -12.602 50.361 1.00 20.18 ? 55 SER H C 1 ATOM 2104 O O . SER B 2 56 ? 1.737 -13.218 49.289 1.00 20.06 ? 55 SER H O 1 ATOM 2105 C CB . SER B 2 56 ? 2.379 -13.426 52.700 1.00 25.03 ? 55 SER H CB 1 ATOM 2106 O OG . SER B 2 56 ? 2.687 -12.571 53.827 1.00 34.46 ? 55 SER H OG 1 ATOM 2107 N N . TYR B 2 57 ? 0.865 -11.675 50.677 1.00 12.46 ? 56 TYR H N 1 ATOM 2108 C CA . TYR B 2 57 ? -0.207 -11.331 49.776 1.00 14.22 ? 56 TYR H CA 1 ATOM 2109 C C . TYR B 2 57 ? 0.160 -9.942 49.337 1.00 12.93 ? 56 TYR H C 1 ATOM 2110 O O . TYR B 2 57 ? 0.555 -9.096 50.135 1.00 12.25 ? 56 TYR H O 1 ATOM 2111 C CB . TYR B 2 57 ? -1.594 -11.251 50.438 1.00 15.76 ? 56 TYR H CB 1 ATOM 2112 C CG . TYR B 2 57 ? -1.804 -12.392 51.390 1.00 14.76 ? 56 TYR H CG 1 ATOM 2113 C CD1 . TYR B 2 57 ? -1.901 -13.700 50.973 1.00 19.64 ? 56 TYR H CD1 1 ATOM 2114 C CD2 . TYR B 2 57 ? -1.789 -12.090 52.709 1.00 19.86 ? 56 TYR H CD2 1 ATOM 2115 C CE1 . TYR B 2 57 ? -1.954 -14.729 51.897 1.00 23.24 ? 56 TYR H CE1 1 ATOM 2116 C CE2 . TYR B 2 57 ? -1.849 -13.108 53.630 1.00 27.71 ? 56 TYR H CE2 1 ATOM 2117 C CZ . TYR B 2 57 ? -1.924 -14.426 53.240 1.00 25.78 ? 56 TYR H CZ 1 ATOM 2118 O OH . TYR B 2 57 ? -1.928 -15.407 54.227 1.00 24.02 ? 56 TYR H OH 1 ATOM 2119 N N . THR B 2 58 ? -0.105 -9.748 48.063 1.00 19.69 ? 57 THR H N 1 ATOM 2120 C CA . THR B 2 58 ? 0.155 -8.539 47.332 1.00 21.87 ? 57 THR H CA 1 ATOM 2121 C C . THR B 2 58 ? -1.050 -8.221 46.451 1.00 26.13 ? 57 THR H C 1 ATOM 2122 O O . THR B 2 58 ? -1.665 -9.115 45.858 1.00 33.31 ? 57 THR H O 1 ATOM 2123 C CB . THR B 2 58 ? 1.438 -8.881 46.645 1.00 21.96 ? 57 THR H CB 1 ATOM 2124 O OG1 . THR B 2 58 ? 2.315 -8.167 47.486 1.00 27.28 ? 57 THR H OG1 1 ATOM 2125 C CG2 . THR B 2 58 ? 1.595 -8.586 45.182 1.00 21.48 ? 57 THR H CG2 1 ATOM 2126 N N . PHE B 2 59 ? -1.368 -6.931 46.382 1.00 26.09 ? 58 PHE H N 1 ATOM 2127 C CA . PHE B 2 59 ? -2.616 -6.467 45.830 1.00 24.73 ? 58 PHE H CA 1 ATOM 2128 C C . PHE B 2 59 ? -2.460 -5.456 44.694 1.00 22.33 ? 58 PHE H C 1 ATOM 2129 O O . PHE B 2 59 ? -1.514 -4.685 44.748 1.00 20.17 ? 58 PHE H O 1 ATOM 2130 C CB . PHE B 2 59 ? -3.361 -5.915 47.027 1.00 23.17 ? 58 PHE H CB 1 ATOM 2131 C CG . PHE B 2 59 ? -3.638 -6.864 48.208 1.00 28.00 ? 58 PHE H CG 1 ATOM 2132 C CD1 . PHE B 2 59 ? -4.796 -7.632 48.261 1.00 30.86 ? 58 PHE H CD1 1 ATOM 2133 C CD2 . PHE B 2 59 ? -2.773 -6.915 49.290 1.00 29.11 ? 58 PHE H CD2 1 ATOM 2134 C CE1 . PHE B 2 59 ? -5.078 -8.420 49.370 1.00 30.90 ? 58 PHE H CE1 1 ATOM 2135 C CE2 . PHE B 2 59 ? -3.062 -7.706 50.394 1.00 29.48 ? 58 PHE H CE2 1 ATOM 2136 C CZ . PHE B 2 59 ? -4.211 -8.459 50.441 1.00 29.33 ? 58 PHE H CZ 1 ATOM 2137 N N . TYR B 2 60 ? -3.291 -5.377 43.652 1.00 23.58 ? 59 TYR H N 1 ATOM 2138 C CA . TYR B 2 60 ? -3.126 -4.413 42.554 1.00 29.53 ? 59 TYR H CA 1 ATOM 2139 C C . TYR B 2 60 ? -4.472 -3.989 41.968 1.00 31.66 ? 59 TYR H C 1 ATOM 2140 O O . TYR B 2 60 ? -5.408 -4.796 41.991 1.00 34.33 ? 59 TYR H O 1 ATOM 2141 C CB . TYR B 2 60 ? -2.331 -4.978 41.378 1.00 25.14 ? 59 TYR H CB 1 ATOM 2142 C CG . TYR B 2 60 ? -0.944 -5.354 41.811 1.00 28.94 ? 59 TYR H CG 1 ATOM 2143 C CD1 . TYR B 2 60 ? 0.072 -4.424 41.907 1.00 29.25 ? 59 TYR H CD1 1 ATOM 2144 C CD2 . TYR B 2 60 ? -0.706 -6.659 42.127 1.00 31.24 ? 59 TYR H CD2 1 ATOM 2145 C CE1 . TYR B 2 60 ? 1.336 -4.803 42.323 1.00 25.17 ? 59 TYR H CE1 1 ATOM 2146 C CE2 . TYR B 2 60 ? 0.551 -7.034 42.533 1.00 28.19 ? 59 TYR H CE2 1 ATOM 2147 C CZ . TYR B 2 60 ? 1.550 -6.114 42.626 1.00 21.90 ? 59 TYR H CZ 1 ATOM 2148 O OH . TYR B 2 60 ? 2.772 -6.553 43.035 1.00 25.08 ? 59 TYR H OH 1 ATOM 2149 N N . PRO B 2 61 ? -4.666 -2.776 41.436 1.00 30.61 ? 60 PRO H N 1 ATOM 2150 C CA . PRO B 2 61 ? -5.766 -2.433 40.551 1.00 28.37 ? 60 PRO H CA 1 ATOM 2151 C C . PRO B 2 61 ? -5.405 -2.931 39.194 1.00 23.87 ? 60 PRO H C 1 ATOM 2152 O O . PRO B 2 61 ? -4.248 -2.894 38.805 1.00 28.95 ? 60 PRO H O 1 ATOM 2153 C CB . PRO B 2 61 ? -5.886 -0.952 40.532 1.00 28.77 ? 60 PRO H CB 1 ATOM 2154 C CG . PRO B 2 61 ? -5.123 -0.567 41.771 1.00 33.47 ? 60 PRO H CG 1 ATOM 2155 C CD . PRO B 2 61 ? -3.970 -1.564 41.810 1.00 31.82 ? 60 PRO H CD 1 ATOM 2156 N N . ASP B 2 62 ? -6.430 -3.228 38.433 1.00 24.75 ? 61 ASP H N 1 ATOM 2157 C CA . ASP B 2 62 ? -6.308 -3.776 37.108 1.00 29.13 ? 61 ASP H CA 1 ATOM 2158 C C . ASP B 2 62 ? -5.421 -3.005 36.159 1.00 30.65 ? 61 ASP H C 1 ATOM 2159 O O . ASP B 2 62 ? -4.768 -3.599 35.312 1.00 36.55 ? 61 ASP H O 1 ATOM 2160 C CB . ASP B 2 62 ? -7.711 -3.906 36.548 1.00 35.88 ? 61 ASP H CB 1 ATOM 2161 C CG . ASP B 2 62 ? -8.578 -4.973 37.232 1.00 40.67 ? 61 ASP H CG 1 ATOM 2162 O OD1 . ASP B 2 62 ? -8.342 -5.342 38.387 1.00 43.44 ? 61 ASP H OD1 1 ATOM 2163 O OD2 . ASP B 2 62 ? -9.520 -5.440 36.591 1.00 46.79 ? 61 ASP H OD2 1 ATOM 2164 N N . THR B 2 63 ? -5.313 -1.701 36.348 1.00 30.83 ? 62 THR H N 1 ATOM 2165 C CA . THR B 2 63 ? -4.478 -0.800 35.550 1.00 34.09 ? 62 THR H CA 1 ATOM 2166 C C . THR B 2 63 ? -2.984 -1.096 35.548 1.00 31.78 ? 62 THR H C 1 ATOM 2167 O O . THR B 2 63 ? -2.208 -0.699 34.680 1.00 31.51 ? 62 THR H O 1 ATOM 2168 C CB . THR B 2 63 ? -4.719 0.614 36.078 1.00 38.35 ? 62 THR H CB 1 ATOM 2169 O OG1 . THR B 2 63 ? -6.141 0.677 36.180 1.00 41.81 ? 62 THR H OG1 1 ATOM 2170 C CG2 . THR B 2 63 ? -4.128 1.755 35.233 1.00 44.03 ? 62 THR H CG2 1 ATOM 2171 N N . VAL B 2 64 ? -2.566 -1.686 36.643 1.00 27.41 ? 63 VAL H N 1 ATOM 2172 C CA . VAL B 2 64 ? -1.173 -1.943 36.821 1.00 29.84 ? 63 VAL H CA 1 ATOM 2173 C C . VAL B 2 64 ? -0.884 -3.406 37.079 1.00 32.86 ? 63 VAL H C 1 ATOM 2174 O O . VAL B 2 64 ? 0.299 -3.781 37.129 1.00 36.28 ? 63 VAL H O 1 ATOM 2175 C CB . VAL B 2 64 ? -0.681 -1.052 37.983 1.00 27.80 ? 63 VAL H CB 1 ATOM 2176 C CG1 . VAL B 2 64 ? -0.887 0.389 37.538 1.00 21.89 ? 63 VAL H CG1 1 ATOM 2177 C CG2 . VAL B 2 64 ? -1.377 -1.397 39.307 1.00 17.32 ? 63 VAL H CG2 1 ATOM 2178 N N . LYS B 2 65 ? -1.940 -4.226 37.224 1.00 34.98 ? 64 LYS H N 1 ATOM 2179 C CA . LYS B 2 65 ? -1.790 -5.636 37.557 1.00 35.39 ? 64 LYS H CA 1 ATOM 2180 C C . LYS B 2 65 ? -1.026 -6.275 36.401 1.00 36.93 ? 64 LYS H C 1 ATOM 2181 O O . LYS B 2 65 ? -1.252 -6.042 35.203 1.00 33.92 ? 64 LYS H O 1 ATOM 2182 C CB . LYS B 2 65 ? -3.148 -6.362 37.726 1.00 29.29 ? 64 LYS H CB 1 ATOM 2183 C CG . LYS B 2 65 ? -2.966 -7.701 38.491 1.00 28.96 ? 64 LYS H CG 1 ATOM 2184 C CD . LYS B 2 65 ? -4.241 -8.462 38.813 1.00 28.37 ? 64 LYS H CD 1 ATOM 2185 C CE . LYS B 2 65 ? -5.056 -7.777 39.924 1.00 37.56 ? 64 LYS H CE 1 ATOM 2186 N NZ . LYS B 2 65 ? -6.503 -7.829 39.700 1.00 40.52 ? 64 LYS H NZ 1 ATOM 2187 N N . GLY B 2 66 ? 0.024 -6.980 36.807 1.00 39.27 ? 65 GLY H N 1 ATOM 2188 C CA . GLY B 2 66 ? 0.851 -7.607 35.814 1.00 42.77 ? 65 GLY H CA 1 ATOM 2189 C C . GLY B 2 66 ? 1.964 -6.687 35.358 1.00 43.25 ? 65 GLY H C 1 ATOM 2190 O O . GLY B 2 66 ? 3.096 -7.157 35.391 1.00 51.37 ? 65 GLY H O 1 ATOM 2191 N N . ARG B 2 67 ? 1.785 -5.429 34.944 1.00 38.80 ? 66 ARG H N 1 ATOM 2192 C CA . ARG B 2 67 ? 2.975 -4.671 34.568 1.00 34.86 ? 66 ARG H CA 1 ATOM 2193 C C . ARG B 2 67 ? 3.744 -3.949 35.692 1.00 32.50 ? 66 ARG H C 1 ATOM 2194 O O . ARG B 2 67 ? 4.784 -3.327 35.418 1.00 32.89 ? 66 ARG H O 1 ATOM 2195 C CB . ARG B 2 67 ? 2.585 -3.695 33.454 1.00 32.73 ? 66 ARG H CB 1 ATOM 2196 C CG . ARG B 2 67 ? 1.336 -2.898 33.680 1.00 33.85 ? 66 ARG H CG 1 ATOM 2197 C CD . ARG B 2 67 ? 1.196 -1.841 32.600 1.00 36.61 ? 66 ARG H CD 1 ATOM 2198 N NE . ARG B 2 67 ? 0.281 -0.835 33.128 1.00 40.02 ? 66 ARG H NE 1 ATOM 2199 C CZ . ARG B 2 67 ? 0.607 0.447 33.270 1.00 34.70 ? 66 ARG H CZ 1 ATOM 2200 N NH1 . ARG B 2 67 ? 1.763 0.909 32.803 1.00 34.34 ? 66 ARG H NH1 1 ATOM 2201 N NH2 . ARG B 2 67 ? -0.272 1.268 33.843 1.00 34.32 ? 66 ARG H NH2 1 ATOM 2202 N N . PHE B 2 68 ? 3.290 -3.965 36.953 1.00 24.52 ? 67 PHE H N 1 ATOM 2203 C CA . PHE B 2 68 ? 3.999 -3.358 38.077 1.00 21.34 ? 67 PHE H CA 1 ATOM 2204 C C . PHE B 2 68 ? 4.067 -4.442 39.101 1.00 20.34 ? 67 PHE H C 1 ATOM 2205 O O . PHE B 2 68 ? 3.097 -5.190 39.248 1.00 31.68 ? 67 PHE H O 1 ATOM 2206 C CB . PHE B 2 68 ? 3.278 -2.224 38.802 1.00 22.52 ? 67 PHE H CB 1 ATOM 2207 C CG . PHE B 2 68 ? 3.028 -0.928 38.046 1.00 23.97 ? 67 PHE H CG 1 ATOM 2208 C CD1 . PHE B 2 68 ? 3.257 -0.804 36.687 1.00 24.51 ? 67 PHE H CD1 1 ATOM 2209 C CD2 . PHE B 2 68 ? 2.529 0.134 38.752 1.00 23.13 ? 67 PHE H CD2 1 ATOM 2210 C CE1 . PHE B 2 68 ? 2.980 0.372 36.039 1.00 24.76 ? 67 PHE H CE1 1 ATOM 2211 C CE2 . PHE B 2 68 ? 2.256 1.310 38.094 1.00 25.04 ? 67 PHE H CE2 1 ATOM 2212 C CZ . PHE B 2 68 ? 2.477 1.432 36.743 1.00 24.20 ? 67 PHE H CZ 1 ATOM 2213 N N . ILE B 2 69 ? 5.156 -4.545 39.833 1.00 16.42 ? 68 ILE H N 1 ATOM 2214 C CA . ILE B 2 69 ? 5.355 -5.573 40.848 1.00 17.60 ? 68 ILE H CA 1 ATOM 2215 C C . ILE B 2 69 ? 5.662 -4.747 42.083 1.00 23.04 ? 68 ILE H C 1 ATOM 2216 O O . ILE B 2 69 ? 6.268 -3.691 41.896 1.00 30.78 ? 68 ILE H O 1 ATOM 2217 C CB . ILE B 2 69 ? 6.579 -6.499 40.519 1.00 14.32 ? 68 ILE H CB 1 ATOM 2218 C CG1 . ILE B 2 69 ? 6.183 -7.688 39.703 1.00 11.79 ? 68 ILE H CG1 1 ATOM 2219 C CG2 . ILE B 2 69 ? 7.157 -7.099 41.775 1.00 13.25 ? 68 ILE H CG2 1 ATOM 2220 C CD1 . ILE B 2 69 ? 5.896 -7.449 38.228 1.00 14.31 ? 68 ILE H CD1 1 ATOM 2221 N N . ILE B 2 70 ? 5.252 -5.111 43.302 1.00 19.21 ? 69 ILE H N 1 ATOM 2222 C CA . ILE B 2 70 ? 5.712 -4.425 44.498 1.00 20.87 ? 69 ILE H CA 1 ATOM 2223 C C . ILE B 2 70 ? 6.633 -5.437 45.220 1.00 23.88 ? 69 ILE H C 1 ATOM 2224 O O . ILE B 2 70 ? 6.559 -6.621 44.886 1.00 29.75 ? 69 ILE H O 1 ATOM 2225 C CB . ILE B 2 70 ? 4.468 -3.975 45.325 1.00 16.88 ? 69 ILE H CB 1 ATOM 2226 C CG1 . ILE B 2 70 ? 4.940 -3.159 46.526 1.00 11.33 ? 69 ILE H CG1 1 ATOM 2227 C CG2 . ILE B 2 70 ? 3.650 -5.162 45.766 1.00 17.94 ? 69 ILE H CG2 1 ATOM 2228 C CD1 . ILE B 2 70 ? 3.821 -2.412 47.268 1.00 4.54 ? 69 ILE H CD1 1 ATOM 2229 N N . SER B 2 71 ? 7.555 -5.079 46.128 1.00 16.33 ? 70 SER H N 1 ATOM 2230 C CA . SER B 2 71 ? 8.484 -5.999 46.786 1.00 13.59 ? 70 SER H CA 1 ATOM 2231 C C . SER B 2 71 ? 8.799 -5.341 48.100 1.00 14.65 ? 70 SER H C 1 ATOM 2232 O O . SER B 2 71 ? 8.770 -4.117 48.120 1.00 23.49 ? 70 SER H O 1 ATOM 2233 C CB . SER B 2 71 ? 9.845 -6.114 46.137 1.00 17.24 ? 70 SER H CB 1 ATOM 2234 O OG . SER B 2 71 ? 9.885 -6.300 44.733 1.00 28.03 ? 70 SER H OG 1 ATOM 2235 N N . ARG B 2 72 ? 9.155 -5.967 49.207 1.00 16.07 ? 71 ARG H N 1 ATOM 2236 C CA . ARG B 2 72 ? 9.475 -5.192 50.392 1.00 24.02 ? 71 ARG H CA 1 ATOM 2237 C C . ARG B 2 72 ? 10.683 -5.799 51.076 1.00 31.49 ? 71 ARG H C 1 ATOM 2238 O O . ARG B 2 72 ? 10.591 -6.683 51.922 1.00 39.95 ? 71 ARG H O 1 ATOM 2239 C CB . ARG B 2 72 ? 8.278 -5.164 51.325 1.00 20.87 ? 71 ARG H CB 1 ATOM 2240 C CG . ARG B 2 72 ? 7.667 -6.481 51.752 1.00 12.31 ? 71 ARG H CG 1 ATOM 2241 C CD . ARG B 2 72 ? 6.861 -6.109 52.928 1.00 10.91 ? 71 ARG H CD 1 ATOM 2242 N NE . ARG B 2 72 ? 7.694 -5.651 54.030 1.00 12.40 ? 71 ARG H NE 1 ATOM 2243 C CZ . ARG B 2 72 ? 7.123 -4.955 55.033 1.00 16.86 ? 71 ARG H CZ 1 ATOM 2244 N NH1 . ARG B 2 72 ? 5.821 -4.637 55.001 1.00 12.14 ? 71 ARG H NH1 1 ATOM 2245 N NH2 . ARG B 2 72 ? 7.864 -4.556 56.077 1.00 17.36 ? 71 ARG H NH2 1 ATOM 2246 N N . ASN B 2 73 ? 11.870 -5.270 50.768 1.00 35.31 ? 72 ASN H N 1 ATOM 2247 C CA . ASN B 2 73 ? 13.167 -5.846 51.144 1.00 28.68 ? 72 ASN H CA 1 ATOM 2248 C C . ASN B 2 73 ? 13.532 -5.794 52.620 1.00 23.40 ? 72 ASN H C 1 ATOM 2249 O O . ASN B 2 73 ? 14.706 -5.787 52.986 1.00 17.44 ? 72 ASN H O 1 ATOM 2250 C CB . ASN B 2 73 ? 14.234 -5.150 50.291 1.00 36.49 ? 72 ASN H CB 1 ATOM 2251 C CG . ASN B 2 73 ? 15.538 -5.872 49.965 1.00 38.36 ? 72 ASN H CG 1 ATOM 2252 O OD1 . ASN B 2 73 ? 16.054 -5.736 48.851 1.00 36.93 ? 72 ASN H OD1 1 ATOM 2253 N ND2 . ASN B 2 73 ? 16.152 -6.642 50.848 1.00 34.68 ? 72 ASN H ND2 1 ATOM 2254 N N . ASN B 2 74 ? 12.499 -5.687 53.448 1.00 19.53 ? 73 ASN H N 1 ATOM 2255 C CA . ASN B 2 74 ? 12.426 -5.915 54.878 1.00 23.51 ? 73 ASN H CA 1 ATOM 2256 C C . ASN B 2 74 ? 13.650 -6.229 55.734 1.00 25.96 ? 73 ASN H C 1 ATOM 2257 O O . ASN B 2 74 ? 13.712 -5.892 56.917 1.00 26.47 ? 73 ASN H O 1 ATOM 2258 C CB . ASN B 2 74 ? 11.382 -7.013 55.056 1.00 24.32 ? 73 ASN H CB 1 ATOM 2259 C CG . ASN B 2 74 ? 10.456 -6.881 56.260 1.00 27.28 ? 73 ASN H CG 1 ATOM 2260 O OD1 . ASN B 2 74 ? 9.236 -6.969 56.120 1.00 19.93 ? 73 ASN H OD1 1 ATOM 2261 N ND2 . ASN B 2 74 ? 10.988 -6.682 57.476 1.00 28.29 ? 73 ASN H ND2 1 ATOM 2262 N N . ALA B 2 75 ? 14.642 -6.923 55.216 1.00 29.06 ? 74 ALA H N 1 ATOM 2263 C CA . ALA B 2 75 ? 15.891 -7.111 55.919 1.00 25.09 ? 74 ALA H CA 1 ATOM 2264 C C . ALA B 2 75 ? 16.523 -5.743 55.877 1.00 25.55 ? 74 ALA H C 1 ATOM 2265 O O . ALA B 2 75 ? 16.665 -5.129 56.914 1.00 25.78 ? 74 ALA H O 1 ATOM 2266 C CB . ALA B 2 75 ? 16.752 -8.069 55.162 1.00 31.79 ? 74 ALA H CB 1 ATOM 2267 N N . ARG B 2 76 ? 16.749 -5.177 54.683 1.00 25.46 ? 75 ARG H N 1 ATOM 2268 C CA . ARG B 2 76 ? 17.384 -3.876 54.547 1.00 30.59 ? 75 ARG H CA 1 ATOM 2269 C C . ARG B 2 76 ? 16.449 -2.663 54.706 1.00 30.13 ? 75 ARG H C 1 ATOM 2270 O O . ARG B 2 76 ? 16.826 -1.525 54.477 1.00 24.66 ? 75 ARG H O 1 ATOM 2271 C CB . ARG B 2 76 ? 18.080 -3.907 53.199 1.00 39.47 ? 75 ARG H CB 1 ATOM 2272 C CG . ARG B 2 76 ? 19.324 -4.778 53.332 1.00 54.25 ? 75 ARG H CG 1 ATOM 2273 C CD . ARG B 2 76 ? 20.063 -5.125 52.024 1.00 66.92 ? 75 ARG H CD 1 ATOM 2274 N NE . ARG B 2 76 ? 21.346 -5.768 52.344 1.00 81.07 ? 75 ARG H NE 1 ATOM 2275 C CZ . ARG B 2 76 ? 21.966 -6.725 51.616 1.00 86.33 ? 75 ARG H CZ 1 ATOM 2276 N NH1 . ARG B 2 76 ? 21.464 -7.238 50.478 1.00 87.30 ? 75 ARG H NH1 1 ATOM 2277 N NH2 . ARG B 2 76 ? 23.144 -7.192 52.067 1.00 87.76 ? 75 ARG H NH2 1 ATOM 2278 N N . ASN B 2 77 ? 15.202 -2.888 55.144 1.00 29.57 ? 76 ASN H N 1 ATOM 2279 C CA . ASN B 2 77 ? 14.117 -1.922 55.314 1.00 23.26 ? 76 ASN H CA 1 ATOM 2280 C C . ASN B 2 77 ? 13.739 -1.070 54.122 1.00 22.03 ? 76 ASN H C 1 ATOM 2281 O O . ASN B 2 77 ? 13.189 0.012 54.222 1.00 30.94 ? 76 ASN H O 1 ATOM 2282 C CB . ASN B 2 77 ? 14.410 -1.016 56.524 1.00 23.00 ? 76 ASN H CB 1 ATOM 2283 C CG . ASN B 2 77 ? 13.879 -1.528 57.875 1.00 28.66 ? 76 ASN H CG 1 ATOM 2284 O OD1 . ASN B 2 77 ? 13.611 -0.773 58.804 1.00 31.29 ? 76 ASN H OD1 1 ATOM 2285 N ND2 . ASN B 2 77 ? 13.665 -2.793 58.205 1.00 32.12 ? 76 ASN H ND2 1 ATOM 2286 N N . THR B 2 78 ? 13.972 -1.599 52.948 1.00 21.05 ? 77 THR H N 1 ATOM 2287 C CA . THR B 2 78 ? 13.561 -1.089 51.646 1.00 25.21 ? 77 THR H CA 1 ATOM 2288 C C . THR B 2 78 ? 12.128 -1.577 51.341 1.00 25.04 ? 77 THR H C 1 ATOM 2289 O O . THR B 2 78 ? 11.660 -2.568 51.905 1.00 30.90 ? 77 THR H O 1 ATOM 2290 C CB . THR B 2 78 ? 14.604 -1.672 50.634 1.00 35.64 ? 77 THR H CB 1 ATOM 2291 O OG1 . THR B 2 78 ? 15.780 -0.932 50.899 1.00 39.91 ? 77 THR H OG1 1 ATOM 2292 C CG2 . THR B 2 78 ? 14.205 -1.678 49.147 1.00 38.09 ? 77 THR H CG2 1 ATOM 2293 N N . LEU B 2 79 ? 11.485 -0.985 50.341 1.00 25.95 ? 78 LEU H N 1 ATOM 2294 C CA . LEU B 2 79 ? 10.202 -1.335 49.719 1.00 17.53 ? 78 LEU H CA 1 ATOM 2295 C C . LEU B 2 79 ? 10.380 -0.886 48.232 1.00 16.95 ? 78 LEU H C 1 ATOM 2296 O O . LEU B 2 79 ? 10.974 0.173 47.993 1.00 22.45 ? 78 LEU H O 1 ATOM 2297 C CB . LEU B 2 79 ? 9.104 -0.561 50.426 1.00 7.63 ? 78 LEU H CB 1 ATOM 2298 C CG . LEU B 2 79 ? 7.793 -0.384 49.712 1.00 11.17 ? 78 LEU H CG 1 ATOM 2299 C CD1 . LEU B 2 79 ? 6.988 -1.660 49.785 1.00 15.45 ? 78 LEU H CD1 1 ATOM 2300 C CD2 . LEU B 2 79 ? 7.023 0.748 50.366 1.00 12.88 ? 78 LEU H CD2 1 ATOM 2301 N N . SER B 2 80 ? 9.969 -1.540 47.151 1.00 11.26 ? 79 SER H N 1 ATOM 2302 C CA . SER B 2 80 ? 10.306 -1.079 45.816 1.00 12.12 ? 79 SER H CA 1 ATOM 2303 C C . SER B 2 80 ? 9.150 -1.353 44.896 1.00 13.72 ? 79 SER H C 1 ATOM 2304 O O . SER B 2 80 ? 8.348 -2.226 45.227 1.00 16.59 ? 79 SER H O 1 ATOM 2305 C CB . SER B 2 80 ? 11.551 -1.813 45.351 1.00 17.12 ? 79 SER H CB 1 ATOM 2306 O OG . SER B 2 80 ? 12.630 -1.676 46.285 1.00 22.09 ? 79 SER H OG 1 ATOM 2307 N N . LEU B 2 81 ? 8.990 -0.650 43.781 1.00 12.64 ? 80 LEU H N 1 ATOM 2308 C CA . LEU B 2 81 ? 7.850 -0.856 42.905 1.00 14.84 ? 80 LEU H CA 1 ATOM 2309 C C . LEU B 2 81 ? 8.542 -1.110 41.570 1.00 19.35 ? 80 LEU H C 1 ATOM 2310 O O . LEU B 2 81 ? 9.188 -0.201 41.063 1.00 27.36 ? 80 LEU H O 1 ATOM 2311 C CB . LEU B 2 81 ? 6.945 0.416 42.864 1.00 9.55 ? 80 LEU H CB 1 ATOM 2312 C CG . LEU B 2 81 ? 5.636 0.339 42.054 1.00 8.12 ? 80 LEU H CG 1 ATOM 2313 C CD1 . LEU B 2 81 ? 4.749 -0.647 42.770 1.00 12.09 ? 80 LEU H CD1 1 ATOM 2314 C CD2 . LEU B 2 81 ? 4.943 1.688 41.899 1.00 2.00 ? 80 LEU H CD2 1 ATOM 2315 N N . GLN B 2 82 ? 8.522 -2.309 40.975 1.00 22.09 ? 81 GLN H N 1 ATOM 2316 C CA . GLN B 2 82 ? 9.282 -2.616 39.777 1.00 21.97 ? 81 GLN H CA 1 ATOM 2317 C C . GLN B 2 82 ? 8.251 -2.473 38.690 1.00 22.81 ? 81 GLN H C 1 ATOM 2318 O O . GLN B 2 82 ? 7.309 -3.262 38.746 1.00 29.89 ? 81 GLN H O 1 ATOM 2319 C CB . GLN B 2 82 ? 9.809 -4.046 39.919 1.00 24.14 ? 81 GLN H CB 1 ATOM 2320 C CG . GLN B 2 82 ? 11.119 -4.330 39.193 1.00 30.44 ? 81 GLN H CG 1 ATOM 2321 C CD . GLN B 2 82 ? 11.037 -4.149 37.680 1.00 36.49 ? 81 GLN H CD 1 ATOM 2322 O OE1 . GLN B 2 82 ? 10.133 -4.697 37.069 1.00 41.44 ? 81 GLN H OE1 1 ATOM 2323 N NE2 . GLN B 2 82 ? 11.889 -3.417 36.962 1.00 38.29 ? 81 GLN H NE2 1 ATOM 2324 N N . MET B 2 83 ? 8.331 -1.531 37.748 1.00 18.97 ? 82 MET H N 1 ATOM 2325 C CA . MET B 2 83 ? 7.262 -1.363 36.774 1.00 19.63 ? 82 MET H CA 1 ATOM 2326 C C . MET B 2 83 ? 7.742 -1.416 35.356 1.00 21.46 ? 82 MET H C 1 ATOM 2327 O O . MET B 2 83 ? 8.874 -1.016 35.081 1.00 25.28 ? 82 MET H O 1 ATOM 2328 C CB . MET B 2 83 ? 6.541 -0.045 36.945 1.00 19.16 ? 82 MET H CB 1 ATOM 2329 C CG . MET B 2 83 ? 7.204 0.995 37.838 1.00 20.78 ? 82 MET H CG 1 ATOM 2330 S SD . MET B 2 83 ? 6.298 2.557 38.059 1.00 17.42 ? 82 MET H SD 1 ATOM 2331 C CE . MET B 2 83 ? 7.880 3.304 37.985 1.00 19.78 ? 82 MET H CE 1 ATOM 2332 N N . SER B 2 84 A 6.873 -1.829 34.444 1.00 21.45 ? 82 SER H N 1 ATOM 2333 C CA . SER B 2 84 A 7.264 -2.023 33.068 1.00 22.57 ? 82 SER H CA 1 ATOM 2334 C C . SER B 2 84 A 6.207 -1.625 32.054 1.00 24.60 ? 82 SER H C 1 ATOM 2335 O O . SER B 2 84 A 5.032 -1.586 32.437 1.00 28.49 ? 82 SER H O 1 ATOM 2336 C CB . SER B 2 84 A 7.620 -3.486 32.938 1.00 22.83 ? 82 SER H CB 1 ATOM 2337 O OG . SER B 2 84 A 6.603 -4.339 33.438 1.00 24.77 ? 82 SER H OG 1 ATOM 2338 N N . SER B 2 85 B 6.536 -1.370 30.780 1.00 22.04 ? 82 SER H N 1 ATOM 2339 C CA . SER B 2 85 B 5.545 -1.069 29.731 1.00 24.73 ? 82 SER H CA 1 ATOM 2340 C C . SER B 2 85 B 4.800 0.170 30.206 1.00 19.22 ? 82 SER H C 1 ATOM 2341 O O . SER B 2 85 B 3.572 0.253 30.285 1.00 22.24 ? 82 SER H O 1 ATOM 2342 C CB . SER B 2 85 B 4.491 -2.263 29.478 1.00 25.80 ? 82 SER H CB 1 ATOM 2343 O OG . SER B 2 85 B 4.918 -3.639 29.291 1.00 21.40 ? 82 SER H OG 1 ATOM 2344 N N . LEU B 2 86 C 5.605 1.138 30.605 1.00 17.99 ? 82 LEU H N 1 ATOM 2345 C CA . LEU B 2 86 C 5.030 2.350 31.146 1.00 23.52 ? 82 LEU H CA 1 ATOM 2346 C C . LEU B 2 86 C 4.337 3.200 30.079 1.00 28.94 ? 82 LEU H C 1 ATOM 2347 O O . LEU B 2 86 C 4.978 3.920 29.320 1.00 36.52 ? 82 LEU H O 1 ATOM 2348 C CB . LEU B 2 86 C 6.108 3.203 31.824 1.00 14.02 ? 82 LEU H CB 1 ATOM 2349 C CG . LEU B 2 86 C 6.874 2.637 32.959 1.00 2.00 ? 82 LEU H CG 1 ATOM 2350 C CD1 . LEU B 2 86 C 8.281 3.203 32.988 1.00 2.00 ? 82 LEU H CD1 1 ATOM 2351 C CD2 . LEU B 2 86 C 6.075 2.913 34.189 1.00 6.63 ? 82 LEU H CD2 1 ATOM 2352 N N . ARG B 2 87 ? 3.025 3.127 29.956 1.00 27.35 ? 83 ARG H N 1 ATOM 2353 C CA . ARG B 2 87 ? 2.305 4.055 29.103 1.00 29.09 ? 83 ARG H CA 1 ATOM 2354 C C . ARG B 2 87 ? 2.213 5.426 29.781 1.00 27.85 ? 83 ARG H C 1 ATOM 2355 O O . ARG B 2 87 ? 2.390 5.548 30.992 1.00 28.40 ? 83 ARG H O 1 ATOM 2356 C CB . ARG B 2 87 ? 0.926 3.462 28.809 1.00 36.33 ? 83 ARG H CB 1 ATOM 2357 C CG . ARG B 2 87 ? 0.312 2.623 29.910 1.00 42.18 ? 83 ARG H CG 1 ATOM 2358 C CD . ARG B 2 87 ? -0.459 1.446 29.355 1.00 48.42 ? 83 ARG H CD 1 ATOM 2359 N NE . ARG B 2 87 ? -1.877 1.640 29.634 1.00 55.59 ? 83 ARG H NE 1 ATOM 2360 C CZ . ARG B 2 87 ? -2.538 1.001 30.624 1.00 57.27 ? 83 ARG H CZ 1 ATOM 2361 N NH1 . ARG B 2 87 ? -1.967 0.073 31.401 1.00 53.15 ? 83 ARG H NH1 1 ATOM 2362 N NH2 . ARG B 2 87 ? -3.832 1.284 30.821 1.00 59.72 ? 83 ARG H NH2 1 ATOM 2363 N N . SER B 2 88 ? 1.881 6.525 29.111 1.00 30.31 ? 84 SER H N 1 ATOM 2364 C CA . SER B 2 88 ? 1.832 7.860 29.714 1.00 28.56 ? 84 SER H CA 1 ATOM 2365 C C . SER B 2 88 ? 0.855 8.088 30.878 1.00 25.17 ? 84 SER H C 1 ATOM 2366 O O . SER B 2 88 ? 0.995 9.052 31.639 1.00 20.45 ? 84 SER H O 1 ATOM 2367 C CB . SER B 2 88 ? 1.521 8.854 28.630 1.00 26.24 ? 84 SER H CB 1 ATOM 2368 O OG . SER B 2 88 ? 0.208 8.520 28.192 1.00 33.50 ? 84 SER H OG 1 ATOM 2369 N N . GLU B 2 89 ? -0.181 7.273 31.084 1.00 22.44 ? 85 GLU H N 1 ATOM 2370 C CA . GLU B 2 89 ? -0.995 7.467 32.281 1.00 25.71 ? 85 GLU H CA 1 ATOM 2371 C C . GLU B 2 89 ? -0.195 7.151 33.559 1.00 22.82 ? 85 GLU H C 1 ATOM 2372 O O . GLU B 2 89 ? -0.730 7.266 34.663 1.00 25.41 ? 85 GLU H O 1 ATOM 2373 C CB . GLU B 2 89 ? -2.257 6.585 32.310 1.00 32.15 ? 85 GLU H CB 1 ATOM 2374 C CG . GLU B 2 89 ? -3.133 6.736 31.089 1.00 41.19 ? 85 GLU H CG 1 ATOM 2375 C CD . GLU B 2 89 ? -2.859 5.608 30.114 1.00 47.35 ? 85 GLU H CD 1 ATOM 2376 O OE1 . GLU B 2 89 ? -1.908 5.725 29.328 1.00 44.87 ? 85 GLU H OE1 1 ATOM 2377 O OE2 . GLU B 2 89 ? -3.594 4.612 30.176 1.00 49.49 ? 85 GLU H OE2 1 ATOM 2378 N N . ASP B 2 90 ? 1.079 6.746 33.503 1.00 15.65 ? 86 ASP H N 1 ATOM 2379 C CA . ASP B 2 90 ? 1.794 6.535 34.745 1.00 17.78 ? 86 ASP H CA 1 ATOM 2380 C C . ASP B 2 90 ? 2.509 7.789 35.192 1.00 20.36 ? 86 ASP H C 1 ATOM 2381 O O . ASP B 2 90 ? 3.069 7.845 36.297 1.00 20.50 ? 86 ASP H O 1 ATOM 2382 C CB . ASP B 2 90 ? 2.765 5.405 34.552 1.00 15.80 ? 86 ASP H CB 1 ATOM 2383 C CG . ASP B 2 90 ? 1.972 4.198 34.104 1.00 13.35 ? 86 ASP H CG 1 ATOM 2384 O OD1 . ASP B 2 90 ? 1.164 3.704 34.877 1.00 17.16 ? 86 ASP H OD1 1 ATOM 2385 O OD2 . ASP B 2 90 ? 2.124 3.783 32.967 1.00 10.30 ? 86 ASP H OD2 1 ATOM 2386 N N . THR B 2 91 ? 2.498 8.791 34.300 1.00 16.74 ? 87 THR H N 1 ATOM 2387 C CA . THR B 2 91 ? 3.115 10.074 34.573 1.00 13.95 ? 87 THR H CA 1 ATOM 2388 C C . THR B 2 91 ? 2.427 10.633 35.795 1.00 13.93 ? 87 THR H C 1 ATOM 2389 O O . THR B 2 91 ? 1.217 10.901 35.738 1.00 22.98 ? 87 THR H O 1 ATOM 2390 C CB . THR B 2 91 ? 2.904 10.991 33.414 1.00 9.21 ? 87 THR H CB 1 ATOM 2391 O OG1 . THR B 2 91 ? 3.299 10.287 32.262 1.00 11.58 ? 87 THR H OG1 1 ATOM 2392 C CG2 . THR B 2 91 ? 3.786 12.183 33.479 1.00 10.37 ? 87 THR H CG2 1 ATOM 2393 N N . ALA B 2 92 ? 3.173 10.770 36.880 1.00 5.99 ? 88 ALA H N 1 ATOM 2394 C CA . ALA B 2 92 ? 2.552 11.149 38.127 1.00 13.06 ? 88 ALA H CA 1 ATOM 2395 C C . ALA B 2 92 ? 3.641 11.218 39.182 1.00 17.63 ? 88 ALA H C 1 ATOM 2396 O O . ALA B 2 92 ? 4.825 11.009 38.885 1.00 18.00 ? 88 ALA H O 1 ATOM 2397 C CB . ALA B 2 92 ? 1.519 10.080 38.537 1.00 14.09 ? 88 ALA H CB 1 ATOM 2398 N N . ILE B 2 93 ? 3.250 11.476 40.427 1.00 18.55 ? 89 ILE H N 1 ATOM 2399 C CA . ILE B 2 93 ? 4.172 11.492 41.553 1.00 20.05 ? 89 ILE H CA 1 ATOM 2400 C C . ILE B 2 93 ? 3.851 10.265 42.420 1.00 16.73 ? 89 ILE H C 1 ATOM 2401 O O . ILE B 2 93 ? 2.683 10.081 42.818 1.00 17.31 ? 89 ILE H O 1 ATOM 2402 C CB . ILE B 2 93 ? 3.936 12.820 42.274 1.00 24.69 ? 89 ILE H CB 1 ATOM 2403 C CG1 . ILE B 2 93 ? 3.977 13.951 41.239 1.00 25.29 ? 89 ILE H CG1 1 ATOM 2404 C CG2 . ILE B 2 93 ? 4.944 12.964 43.409 1.00 23.61 ? 89 ILE H CG2 1 ATOM 2405 C CD1 . ILE B 2 93 ? 3.596 15.354 41.710 1.00 32.07 ? 89 ILE H CD1 1 ATOM 2406 N N . TYR B 2 94 ? 4.811 9.402 42.745 1.00 6.28 ? 90 TYR H N 1 ATOM 2407 C CA . TYR B 2 94 ? 4.496 8.170 43.438 1.00 4.08 ? 90 TYR H CA 1 ATOM 2408 C C . TYR B 2 94 ? 4.896 8.322 44.856 1.00 5.78 ? 90 TYR H C 1 ATOM 2409 O O . TYR B 2 94 ? 6.016 8.725 45.139 1.00 9.56 ? 90 TYR H O 1 ATOM 2410 C CB . TYR B 2 94 ? 5.242 6.979 42.812 1.00 10.36 ? 90 TYR H CB 1 ATOM 2411 C CG . TYR B 2 94 ? 4.707 6.577 41.435 1.00 11.34 ? 90 TYR H CG 1 ATOM 2412 C CD1 . TYR B 2 94 ? 5.042 7.302 40.325 1.00 11.49 ? 90 TYR H CD1 1 ATOM 2413 C CD2 . TYR B 2 94 ? 3.823 5.524 41.311 1.00 19.64 ? 90 TYR H CD2 1 ATOM 2414 C CE1 . TYR B 2 94 ? 4.496 6.994 39.102 1.00 19.31 ? 90 TYR H CE1 1 ATOM 2415 C CE2 . TYR B 2 94 ? 3.267 5.205 40.087 1.00 20.53 ? 90 TYR H CE2 1 ATOM 2416 C CZ . TYR B 2 94 ? 3.613 5.951 38.994 1.00 22.84 ? 90 TYR H CZ 1 ATOM 2417 O OH . TYR B 2 94 ? 3.088 5.644 37.763 1.00 28.84 ? 90 TYR H OH 1 ATOM 2418 N N . TYR B 2 95 ? 3.966 8.064 45.750 1.00 8.89 ? 91 TYR H N 1 ATOM 2419 C CA . TYR B 2 95 ? 4.179 8.220 47.162 1.00 12.06 ? 91 TYR H CA 1 ATOM 2420 C C . TYR B 2 95 ? 4.185 6.900 47.900 1.00 18.66 ? 91 TYR H C 1 ATOM 2421 O O . TYR B 2 95 ? 3.231 6.127 47.869 1.00 22.43 ? 91 TYR H O 1 ATOM 2422 C CB . TYR B 2 95 ? 3.107 9.007 47.836 1.00 12.90 ? 91 TYR H CB 1 ATOM 2423 C CG . TYR B 2 95 ? 2.935 10.471 47.502 1.00 12.50 ? 91 TYR H CG 1 ATOM 2424 C CD1 . TYR B 2 95 ? 3.782 11.400 48.020 1.00 10.79 ? 91 TYR H CD1 1 ATOM 2425 C CD2 . TYR B 2 95 ? 1.878 10.850 46.727 1.00 9.36 ? 91 TYR H CD2 1 ATOM 2426 C CE1 . TYR B 2 95 ? 3.547 12.719 47.748 1.00 15.93 ? 91 TYR H CE1 1 ATOM 2427 C CE2 . TYR B 2 95 ? 1.641 12.159 46.459 1.00 13.14 ? 91 TYR H CE2 1 ATOM 2428 C CZ . TYR B 2 95 ? 2.481 13.098 46.972 1.00 18.56 ? 91 TYR H CZ 1 ATOM 2429 O OH . TYR B 2 95 ? 2.257 14.441 46.701 1.00 23.51 ? 91 TYR H OH 1 ATOM 2430 N N . CYS B 2 96 ? 5.302 6.615 48.537 1.00 18.67 ? 92 CYS H N 1 ATOM 2431 C CA . CYS B 2 96 ? 5.433 5.497 49.442 1.00 15.84 ? 92 CYS H CA 1 ATOM 2432 C C . CYS B 2 96 ? 4.500 5.758 50.638 1.00 13.58 ? 92 CYS H C 1 ATOM 2433 O O . CYS B 2 96 ? 4.571 6.774 51.332 1.00 7.78 ? 92 CYS H O 1 ATOM 2434 C CB . CYS B 2 96 ? 6.934 5.434 49.828 1.00 21.22 ? 92 CYS H CB 1 ATOM 2435 S SG . CYS B 2 96 ? 7.545 4.137 50.936 1.00 22.17 ? 92 CYS H SG 1 ATOM 2436 N N . THR B 2 97 ? 3.583 4.859 50.910 1.00 20.37 ? 93 THR H N 1 ATOM 2437 C CA . THR B 2 97 ? 2.659 5.011 52.004 1.00 17.78 ? 93 THR H CA 1 ATOM 2438 C C . THR B 2 97 ? 2.727 3.815 52.912 1.00 17.47 ? 93 THR H C 1 ATOM 2439 O O . THR B 2 97 ? 3.105 2.717 52.485 1.00 17.92 ? 93 THR H O 1 ATOM 2440 C CB . THR B 2 97 ? 1.302 5.142 51.435 1.00 16.21 ? 93 THR H CB 1 ATOM 2441 O OG1 . THR B 2 97 ? 1.375 6.101 50.387 1.00 21.65 ? 93 THR H OG1 1 ATOM 2442 C CG2 . THR B 2 97 ? 0.366 5.679 52.437 1.00 15.24 ? 93 THR H CG2 1 ATOM 2443 N N . ARG B 2 98 ? 2.396 4.021 54.181 1.00 17.83 ? 94 ARG H N 1 ATOM 2444 C CA . ARG B 2 98 ? 2.289 2.901 55.095 1.00 18.22 ? 94 ARG H CA 1 ATOM 2445 C C . ARG B 2 98 ? 0.881 2.883 55.690 1.00 22.89 ? 94 ARG H C 1 ATOM 2446 O O . ARG B 2 98 ? 0.303 3.945 56.018 1.00 24.73 ? 94 ARG H O 1 ATOM 2447 C CB . ARG B 2 98 ? 3.294 2.984 56.235 1.00 7.64 ? 94 ARG H CB 1 ATOM 2448 C CG . ARG B 2 98 ? 2.838 3.548 57.550 1.00 4.73 ? 94 ARG H CG 1 ATOM 2449 C CD . ARG B 2 98 ? 3.552 2.608 58.454 1.00 8.09 ? 94 ARG H CD 1 ATOM 2450 N NE . ARG B 2 98 ? 4.250 3.260 59.551 1.00 14.55 ? 94 ARG H NE 1 ATOM 2451 C CZ . ARG B 2 98 ? 3.651 3.943 60.546 1.00 16.96 ? 94 ARG H CZ 1 ATOM 2452 N NH1 . ARG B 2 98 ? 2.346 4.221 60.625 1.00 7.54 ? 94 ARG H NH1 1 ATOM 2453 N NH2 . ARG B 2 98 ? 4.423 4.397 61.517 1.00 24.82 ? 94 ARG H NH2 1 ATOM 2454 N N . TYR B 2 99 ? 0.374 1.645 55.764 1.00 17.65 ? 95 TYR H N 1 ATOM 2455 C CA . TYR B 2 99 ? -0.915 1.384 56.340 1.00 14.71 ? 95 TYR H CA 1 ATOM 2456 C C . TYR B 2 99 ? -0.814 1.374 57.840 1.00 17.53 ? 95 TYR H C 1 ATOM 2457 O O . TYR B 2 99 ? 0.285 1.308 58.415 1.00 21.83 ? 95 TYR H O 1 ATOM 2458 C CB . TYR B 2 99 ? -1.432 0.062 55.981 1.00 11.63 ? 95 TYR H CB 1 ATOM 2459 C CG . TYR B 2 99 ? -1.847 -0.068 54.556 1.00 6.90 ? 95 TYR H CG 1 ATOM 2460 C CD1 . TYR B 2 99 ? -0.851 -0.337 53.648 1.00 5.20 ? 95 TYR H CD1 1 ATOM 2461 C CD2 . TYR B 2 99 ? -3.188 0.007 54.213 1.00 2.00 ? 95 TYR H CD2 1 ATOM 2462 C CE1 . TYR B 2 99 ? -1.209 -0.562 52.345 1.00 7.74 ? 95 TYR H CE1 1 ATOM 2463 C CE2 . TYR B 2 99 ? -3.539 -0.223 52.896 1.00 6.75 ? 95 TYR H CE2 1 ATOM 2464 C CZ . TYR B 2 99 ? -2.540 -0.517 51.964 1.00 7.12 ? 95 TYR H CZ 1 ATOM 2465 O OH . TYR B 2 99 ? -2.828 -0.876 50.651 1.00 8.93 ? 95 TYR H OH 1 ATOM 2466 N N . SER B 2 100 ? -1.972 1.454 58.475 1.00 18.08 ? 96 SER H N 1 ATOM 2467 C CA . SER B 2 100 ? -1.966 1.366 59.910 1.00 25.21 ? 96 SER H CA 1 ATOM 2468 C C . SER B 2 100 ? -2.072 -0.106 60.245 1.00 25.80 ? 96 SER H C 1 ATOM 2469 O O . SER B 2 100 ? -2.353 -0.926 59.362 1.00 24.46 ? 96 SER H O 1 ATOM 2470 C CB . SER B 2 100 ? -3.150 2.124 60.468 1.00 29.77 ? 96 SER H CB 1 ATOM 2471 O OG . SER B 2 100 ? -4.349 1.568 59.935 1.00 35.34 ? 96 SER H OG 1 ATOM 2472 N N . SER B 2 101 ? -2.046 -0.415 61.564 1.00 29.38 ? 97 SER H N 1 ATOM 2473 C CA . SER B 2 101 ? -2.152 -1.773 62.122 1.00 25.94 ? 97 SER H CA 1 ATOM 2474 C C . SER B 2 101 ? -3.424 -2.436 61.723 1.00 27.70 ? 97 SER H C 1 ATOM 2475 O O . SER B 2 101 ? -3.647 -3.612 61.933 1.00 38.54 ? 97 SER H O 1 ATOM 2476 C CB . SER B 2 101 ? -2.147 -1.778 63.611 1.00 24.55 ? 97 SER H CB 1 ATOM 2477 O OG . SER B 2 101 ? -1.118 -0.902 64.051 1.00 34.68 ? 97 SER H OG 1 ATOM 2478 N N . ASP B 2 102 ? -4.298 -1.627 61.187 1.00 29.63 ? 98 ASP H N 1 ATOM 2479 C CA . ASP B 2 102 ? -5.540 -2.079 60.690 1.00 33.72 ? 98 ASP H CA 1 ATOM 2480 C C . ASP B 2 102 ? -5.401 -1.853 59.184 1.00 31.09 ? 98 ASP H C 1 ATOM 2481 O O . ASP B 2 102 ? -5.818 -0.824 58.654 1.00 33.58 ? 98 ASP H O 1 ATOM 2482 C CB . ASP B 2 102 ? -6.512 -1.194 61.408 1.00 42.27 ? 98 ASP H CB 1 ATOM 2483 C CG . ASP B 2 102 ? -7.942 -1.643 61.320 1.00 45.85 ? 98 ASP H CG 1 ATOM 2484 O OD1 . ASP B 2 102 ? -8.246 -2.470 60.465 1.00 45.97 ? 98 ASP H OD1 1 ATOM 2485 O OD2 . ASP B 2 102 ? -8.739 -1.148 62.117 1.00 51.22 ? 98 ASP H OD2 1 ATOM 2486 N N . PRO B 2 103 ? -4.788 -2.746 58.439 1.00 25.67 ? 99 PRO H N 1 ATOM 2487 C CA . PRO B 2 103 ? -4.330 -2.475 57.088 1.00 23.00 ? 99 PRO H CA 1 ATOM 2488 C C . PRO B 2 103 ? -5.328 -2.194 55.970 1.00 19.19 ? 99 PRO H C 1 ATOM 2489 O O . PRO B 2 103 ? -5.257 -2.819 54.909 1.00 17.59 ? 99 PRO H O 1 ATOM 2490 C CB . PRO B 2 103 ? -3.433 -3.668 56.814 1.00 24.48 ? 99 PRO H CB 1 ATOM 2491 C CG . PRO B 2 103 ? -4.115 -4.780 57.579 1.00 30.20 ? 99 PRO H CG 1 ATOM 2492 C CD . PRO B 2 103 ? -4.444 -4.085 58.886 1.00 26.84 ? 99 PRO H CD 1 ATOM 2493 N N . PHE B 2 104 ? -6.263 -1.257 56.126 1.00 18.38 ? 100 PHE H N 1 ATOM 2494 C CA . PHE B 2 104 ? -7.192 -0.936 55.056 1.00 20.68 ? 100 PHE H CA 1 ATOM 2495 C C . PHE B 2 104 ? -7.072 0.533 54.772 1.00 18.00 ? 100 PHE H C 1 ATOM 2496 O O . PHE B 2 104 ? -7.778 0.942 53.856 1.00 15.46 ? 100 PHE H O 1 ATOM 2497 C CB . PHE B 2 104 ? -8.676 -1.246 55.418 1.00 30.81 ? 100 PHE H CB 1 ATOM 2498 C CG . PHE B 2 104 ? -8.680 -2.652 55.969 1.00 41.32 ? 100 PHE H CG 1 ATOM 2499 C CD1 . PHE B 2 104 ? -8.603 -3.729 55.108 1.00 41.34 ? 100 PHE H CD1 1 ATOM 2500 C CD2 . PHE B 2 104 ? -8.559 -2.830 57.328 1.00 43.23 ? 100 PHE H CD2 1 ATOM 2501 C CE1 . PHE B 2 104 ? -8.377 -4.987 55.611 1.00 42.96 ? 100 PHE H CE1 1 ATOM 2502 C CE2 . PHE B 2 104 ? -8.333 -4.093 57.815 1.00 46.92 ? 100 PHE H CE2 1 ATOM 2503 C CZ . PHE B 2 104 ? -8.237 -5.168 56.963 1.00 46.63 ? 100 PHE H CZ 1 ATOM 2504 N N . TYR B 2 105 B -6.266 1.345 55.501 1.00 15.90 ? 100 TYR H N 1 ATOM 2505 C CA . TYR B 2 105 B -6.113 2.776 55.224 1.00 18.65 ? 100 TYR H CA 1 ATOM 2506 C C . TYR B 2 105 B -4.712 3.246 55.596 1.00 22.63 ? 100 TYR H C 1 ATOM 2507 O O . TYR B 2 105 B -4.077 2.667 56.494 1.00 28.51 ? 100 TYR H O 1 ATOM 2508 C CB . TYR B 2 105 B -7.123 3.636 56.000 1.00 14.35 ? 100 TYR H CB 1 ATOM 2509 C CG . TYR B 2 105 B -6.910 3.639 57.500 1.00 17.27 ? 100 TYR H CG 1 ATOM 2510 C CD1 . TYR B 2 105 B -6.066 4.582 58.025 1.00 16.92 ? 100 TYR H CD1 1 ATOM 2511 C CD2 . TYR B 2 105 B -7.548 2.733 58.323 1.00 17.84 ? 100 TYR H CD2 1 ATOM 2512 C CE1 . TYR B 2 105 B -5.848 4.625 59.368 1.00 22.27 ? 100 TYR H CE1 1 ATOM 2513 C CE2 . TYR B 2 105 B -7.339 2.778 59.689 1.00 21.22 ? 100 TYR H CE2 1 ATOM 2514 C CZ . TYR B 2 105 B -6.481 3.738 60.211 1.00 24.27 ? 100 TYR H CZ 1 ATOM 2515 O OH . TYR B 2 105 B -6.228 3.870 61.583 1.00 23.85 ? 100 TYR H OH 1 ATOM 2516 N N . PHE B 2 106 C -4.300 4.360 54.987 1.00 16.34 ? 100 PHE H N 1 ATOM 2517 C CA . PHE B 2 106 C -2.945 4.859 55.101 1.00 7.59 ? 100 PHE H CA 1 ATOM 2518 C C . PHE B 2 106 C -2.730 5.868 56.241 1.00 5.17 ? 100 PHE H C 1 ATOM 2519 O O . PHE B 2 106 C -3.584 6.718 56.457 1.00 4.82 ? 100 PHE H O 1 ATOM 2520 C CB . PHE B 2 106 C -2.589 5.507 53.803 1.00 2.00 ? 100 PHE H CB 1 ATOM 2521 C CG . PHE B 2 106 C -3.006 4.842 52.505 1.00 2.00 ? 100 PHE H CG 1 ATOM 2522 C CD1 . PHE B 2 106 C -2.422 3.679 52.054 1.00 3.20 ? 100 PHE H CD1 1 ATOM 2523 C CD2 . PHE B 2 106 C -3.988 5.440 51.739 1.00 5.31 ? 100 PHE H CD2 1 ATOM 2524 C CE1 . PHE B 2 106 C -2.814 3.111 50.846 1.00 2.00 ? 100 PHE H CE1 1 ATOM 2525 C CE2 . PHE B 2 106 C -4.371 4.870 50.539 1.00 9.11 ? 100 PHE H CE2 1 ATOM 2526 C CZ . PHE B 2 106 C -3.789 3.702 50.084 1.00 4.47 ? 100 PHE H CZ 1 ATOM 2527 N N . ASP B 2 107 ? -1.655 5.906 57.018 1.00 5.22 ? 101 ASP H N 1 ATOM 2528 C CA . ASP B 2 107 ? -1.478 6.966 58.004 1.00 10.53 ? 101 ASP H CA 1 ATOM 2529 C C . ASP B 2 107 ? -0.168 7.761 57.886 1.00 16.49 ? 101 ASP H C 1 ATOM 2530 O O . ASP B 2 107 ? 0.065 8.676 58.671 1.00 13.91 ? 101 ASP H O 1 ATOM 2531 C CB . ASP B 2 107 ? -1.597 6.374 59.396 1.00 8.96 ? 101 ASP H CB 1 ATOM 2532 C CG . ASP B 2 107 ? -0.522 5.388 59.825 1.00 15.79 ? 101 ASP H CG 1 ATOM 2533 O OD1 . ASP B 2 107 ? 0.156 4.777 58.967 1.00 13.55 ? 101 ASP H OD1 1 ATOM 2534 O OD2 . ASP B 2 107 ? -0.386 5.248 61.052 1.00 19.39 ? 101 ASP H OD2 1 ATOM 2535 N N . TYR B 2 108 ? 0.737 7.433 56.939 1.00 24.34 ? 102 TYR H N 1 ATOM 2536 C CA . TYR B 2 108 ? 1.960 8.187 56.631 1.00 21.88 ? 102 TYR H CA 1 ATOM 2537 C C . TYR B 2 108 ? 2.379 8.115 55.155 1.00 25.39 ? 102 TYR H C 1 ATOM 2538 O O . TYR B 2 108 ? 2.412 7.015 54.572 1.00 29.77 ? 102 TYR H O 1 ATOM 2539 C CB . TYR B 2 108 ? 3.118 7.696 57.486 1.00 14.30 ? 102 TYR H CB 1 ATOM 2540 C CG . TYR B 2 108 ? 2.946 8.310 58.856 1.00 16.15 ? 102 TYR H CG 1 ATOM 2541 C CD1 . TYR B 2 108 ? 3.208 9.647 59.035 1.00 19.11 ? 102 TYR H CD1 1 ATOM 2542 C CD2 . TYR B 2 108 ? 2.472 7.547 59.898 1.00 20.55 ? 102 TYR H CD2 1 ATOM 2543 C CE1 . TYR B 2 108 ? 2.982 10.225 60.261 1.00 24.72 ? 102 TYR H CE1 1 ATOM 2544 C CE2 . TYR B 2 108 ? 2.245 8.108 61.129 1.00 24.06 ? 102 TYR H CE2 1 ATOM 2545 C CZ . TYR B 2 108 ? 2.507 9.444 61.300 1.00 29.48 ? 102 TYR H CZ 1 ATOM 2546 O OH . TYR B 2 108 ? 2.313 10.010 62.547 1.00 37.75 ? 102 TYR H OH 1 ATOM 2547 N N . TRP B 2 109 ? 2.627 9.292 54.540 1.00 20.49 ? 103 TRP H N 1 ATOM 2548 C CA . TRP B 2 109 ? 3.078 9.437 53.161 1.00 10.20 ? 103 TRP H CA 1 ATOM 2549 C C . TRP B 2 109 ? 4.520 9.991 53.126 1.00 10.52 ? 103 TRP H C 1 ATOM 2550 O O . TRP B 2 109 ? 5.008 10.781 53.955 1.00 10.29 ? 103 TRP H O 1 ATOM 2551 C CB . TRP B 2 109 ? 2.172 10.396 52.386 1.00 10.76 ? 103 TRP H CB 1 ATOM 2552 C CG . TRP B 2 109 ? 0.679 10.063 52.291 1.00 12.60 ? 103 TRP H CG 1 ATOM 2553 C CD1 . TRP B 2 109 ? -0.116 9.825 53.391 1.00 9.92 ? 103 TRP H CD1 1 ATOM 2554 C CD2 . TRP B 2 109 ? -0.030 10.001 51.117 1.00 9.14 ? 103 TRP H CD2 1 ATOM 2555 N NE1 . TRP B 2 109 ? -1.321 9.622 52.904 1.00 10.66 ? 103 TRP H NE1 1 ATOM 2556 C CE2 . TRP B 2 109 ? -1.310 9.719 51.562 1.00 9.75 ? 103 TRP H CE2 1 ATOM 2557 C CE3 . TRP B 2 109 ? 0.229 10.135 49.774 1.00 5.40 ? 103 TRP H CE3 1 ATOM 2558 C CZ2 . TRP B 2 109 ? -2.348 9.576 50.659 1.00 8.26 ? 103 TRP H CZ2 1 ATOM 2559 C CZ3 . TRP B 2 109 ? -0.804 9.990 48.871 1.00 4.00 ? 103 TRP H CZ3 1 ATOM 2560 C CH2 . TRP B 2 109 ? -2.082 9.717 49.302 1.00 4.21 ? 103 TRP H CH2 1 ATOM 2561 N N . GLY B 2 110 ? 5.276 9.482 52.167 1.00 11.64 ? 104 GLY H N 1 ATOM 2562 C CA . GLY B 2 110 ? 6.638 9.900 51.999 1.00 6.15 ? 104 GLY H CA 1 ATOM 2563 C C . GLY B 2 110 ? 6.606 11.180 51.254 1.00 14.25 ? 104 GLY H C 1 ATOM 2564 O O . GLY B 2 110 ? 5.545 11.779 51.099 1.00 19.32 ? 104 GLY H O 1 ATOM 2565 N N . GLN B 2 111 ? 7.763 11.569 50.744 1.00 18.47 ? 105 GLN H N 1 ATOM 2566 C CA . GLN B 2 111 ? 7.908 12.795 49.964 1.00 21.05 ? 105 GLN H CA 1 ATOM 2567 C C . GLN B 2 111 ? 7.313 12.757 48.552 1.00 19.69 ? 105 GLN H C 1 ATOM 2568 O O . GLN B 2 111 ? 6.793 13.769 48.094 1.00 20.33 ? 105 GLN H O 1 ATOM 2569 C CB . GLN B 2 111 ? 9.405 13.161 49.877 1.00 27.51 ? 105 GLN H CB 1 ATOM 2570 C CG . GLN B 2 111 ? 9.923 13.930 51.103 1.00 44.52 ? 105 GLN H CG 1 ATOM 2571 C CD . GLN B 2 111 ? 10.128 13.186 52.439 1.00 53.19 ? 105 GLN H CD 1 ATOM 2572 O OE1 . GLN B 2 111 ? 10.850 12.186 52.528 1.00 55.98 ? 105 GLN H OE1 1 ATOM 2573 N NE2 . GLN B 2 111 ? 9.546 13.675 53.534 1.00 52.17 ? 105 GLN H NE2 1 ATOM 2574 N N . GLY B 2 112 ? 7.432 11.642 47.821 1.00 18.52 ? 106 GLY H N 1 ATOM 2575 C CA . GLY B 2 112 ? 6.891 11.481 46.476 1.00 12.36 ? 106 GLY H CA 1 ATOM 2576 C C . GLY B 2 112 ? 8.035 11.494 45.490 1.00 9.97 ? 106 GLY H C 1 ATOM 2577 O O . GLY B 2 112 ? 9.057 12.070 45.841 1.00 13.62 ? 106 GLY H O 1 ATOM 2578 N N . THR B 2 113 ? 7.989 10.855 44.321 1.00 11.07 ? 107 THR H N 1 ATOM 2579 C CA . THR B 2 113 ? 9.046 10.925 43.302 1.00 6.25 ? 107 THR H CA 1 ATOM 2580 C C . THR B 2 113 ? 8.269 11.134 42.074 1.00 10.40 ? 107 THR H C 1 ATOM 2581 O O . THR B 2 113 ? 7.120 10.670 42.018 1.00 17.01 ? 107 THR H O 1 ATOM 2582 C CB . THR B 2 113 ? 9.789 9.671 42.961 1.00 8.98 ? 107 THR H CB 1 ATOM 2583 O OG1 . THR B 2 113 ? 9.255 8.642 43.781 1.00 18.72 ? 107 THR H OG1 1 ATOM 2584 C CG2 . THR B 2 113 ? 11.276 9.821 43.183 1.00 14.58 ? 107 THR H CG2 1 ATOM 2585 N N . THR B 2 114 ? 8.795 11.829 41.097 1.00 9.30 ? 108 THR H N 1 ATOM 2586 C CA . THR B 2 114 ? 7.948 11.982 39.950 1.00 11.99 ? 108 THR H CA 1 ATOM 2587 C C . THR B 2 114 ? 8.486 11.062 38.896 1.00 15.27 ? 108 THR H C 1 ATOM 2588 O O . THR B 2 114 ? 9.614 10.588 39.001 1.00 15.90 ? 108 THR H O 1 ATOM 2589 C CB . THR B 2 114 ? 7.949 13.441 39.562 1.00 5.70 ? 108 THR H CB 1 ATOM 2590 O OG1 . THR B 2 114 ? 9.267 13.909 39.648 1.00 22.70 ? 108 THR H OG1 1 ATOM 2591 C CG2 . THR B 2 114 ? 7.249 14.282 40.584 1.00 9.52 ? 108 THR H CG2 1 ATOM 2592 N N . LEU B 2 115 ? 7.604 10.718 37.973 1.00 19.04 ? 109 LEU H N 1 ATOM 2593 C CA . LEU B 2 115 ? 7.913 9.909 36.837 1.00 16.81 ? 109 LEU H CA 1 ATOM 2594 C C . LEU B 2 115 ? 7.192 10.595 35.683 1.00 13.23 ? 109 LEU H C 1 ATOM 2595 O O . LEU B 2 115 ? 6.033 11.009 35.790 1.00 6.33 ? 109 LEU H O 1 ATOM 2596 C CB . LEU B 2 115 ? 7.389 8.497 37.096 1.00 23.86 ? 109 LEU H CB 1 ATOM 2597 C CG . LEU B 2 115 ? 7.442 7.540 35.913 1.00 29.63 ? 109 LEU H CG 1 ATOM 2598 C CD1 . LEU B 2 115 ? 8.876 7.402 35.475 1.00 28.52 ? 109 LEU H CD1 1 ATOM 2599 C CD2 . LEU B 2 115 ? 6.814 6.212 36.279 1.00 31.21 ? 109 LEU H CD2 1 ATOM 2600 N N . THR B 2 116 ? 7.897 10.754 34.578 1.00 15.14 ? 110 THR H N 1 ATOM 2601 C CA . THR B 2 116 ? 7.352 11.358 33.391 1.00 13.15 ? 110 THR H CA 1 ATOM 2602 C C . THR B 2 116 ? 7.650 10.264 32.374 1.00 16.62 ? 110 THR H C 1 ATOM 2603 O O . THR B 2 116 ? 8.773 9.747 32.310 1.00 11.47 ? 110 THR H O 1 ATOM 2604 C CB . THR B 2 116 ? 8.110 12.624 32.964 1.00 15.88 ? 110 THR H CB 1 ATOM 2605 O OG1 . THR B 2 116 ? 8.436 13.409 34.107 1.00 16.45 ? 110 THR H OG1 1 ATOM 2606 C CG2 . THR B 2 116 ? 7.272 13.418 31.964 1.00 12.54 ? 110 THR H CG2 1 ATOM 2607 N N . VAL B 2 117 ? 6.638 9.915 31.592 1.00 14.86 ? 111 VAL H N 1 ATOM 2608 C CA . VAL B 2 117 ? 6.760 8.907 30.588 1.00 16.87 ? 111 VAL H CA 1 ATOM 2609 C C . VAL B 2 117 ? 6.502 9.569 29.245 1.00 24.93 ? 111 VAL H C 1 ATOM 2610 O O . VAL B 2 117 ? 5.331 9.743 28.870 1.00 30.18 ? 111 VAL H O 1 ATOM 2611 C CB . VAL B 2 117 ? 5.739 7.806 30.870 1.00 16.67 ? 111 VAL H CB 1 ATOM 2612 C CG1 . VAL B 2 117 ? 5.711 6.778 29.762 1.00 15.90 ? 111 VAL H CG1 1 ATOM 2613 C CG2 . VAL B 2 117 ? 6.132 7.101 32.146 1.00 20.98 ? 111 VAL H CG2 1 ATOM 2614 N N . SER B 2 118 ? 7.496 10.013 28.484 1.00 24.74 ? 112 SER H N 1 ATOM 2615 C CA . SER B 2 118 ? 7.202 10.496 27.150 1.00 23.67 ? 112 SER H CA 1 ATOM 2616 C C . SER B 2 118 ? 8.443 10.331 26.344 1.00 29.41 ? 112 SER H C 1 ATOM 2617 O O . SER B 2 118 ? 9.568 10.358 26.851 1.00 28.51 ? 112 SER H O 1 ATOM 2618 C CB . SER B 2 118 ? 6.838 11.958 27.091 1.00 23.10 ? 112 SER H CB 1 ATOM 2619 O OG . SER B 2 118 ? 7.791 12.744 27.790 1.00 30.31 ? 112 SER H OG 1 ATOM 2620 N N . SER B 2 119 ? 8.130 10.166 25.070 1.00 33.90 ? 113 SER H N 1 ATOM 2621 C CA . SER B 2 119 ? 9.096 10.117 23.988 1.00 39.20 ? 113 SER H CA 1 ATOM 2622 C C . SER B 2 119 ? 10.021 11.356 23.920 1.00 43.81 ? 113 SER H C 1 ATOM 2623 O O . SER B 2 119 ? 11.230 11.249 23.695 1.00 43.50 ? 113 SER H O 1 ATOM 2624 C CB . SER B 2 119 ? 8.238 9.915 22.726 1.00 39.77 ? 113 SER H CB 1 ATOM 2625 O OG . SER B 2 119 ? 6.877 10.362 22.918 1.00 37.32 ? 113 SER H OG 1 ATOM 2626 N N . ALA B 2 120 ? 9.391 12.538 24.138 1.00 45.57 ? 114 ALA H N 1 ATOM 2627 C CA . ALA B 2 120 ? 9.982 13.890 24.121 1.00 40.88 ? 114 ALA H CA 1 ATOM 2628 C C . ALA B 2 120 ? 11.333 14.112 24.766 1.00 38.23 ? 114 ALA H C 1 ATOM 2629 O O . ALA B 2 120 ? 11.537 13.755 25.918 1.00 41.75 ? 114 ALA H O 1 ATOM 2630 C CB . ALA B 2 120 ? 9.045 14.868 24.790 1.00 42.12 ? 114 ALA H CB 1 ATOM 2631 N N . LYS B 2 121 ? 12.243 14.773 24.061 1.00 40.51 ? 115 LYS H N 1 ATOM 2632 C CA . LYS B 2 121 ? 13.612 14.922 24.537 1.00 39.09 ? 115 LYS H CA 1 ATOM 2633 C C . LYS B 2 121 ? 13.748 15.988 25.597 1.00 38.19 ? 115 LYS H C 1 ATOM 2634 O O . LYS B 2 121 ? 13.167 17.075 25.519 1.00 44.61 ? 115 LYS H O 1 ATOM 2635 C CB . LYS B 2 121 ? 14.568 15.280 23.402 1.00 40.39 ? 115 LYS H CB 1 ATOM 2636 C CG . LYS B 2 121 ? 14.168 16.558 22.656 1.00 51.07 ? 115 LYS H CG 1 ATOM 2637 C CD . LYS B 2 121 ? 15.235 17.096 21.704 1.00 55.72 ? 115 LYS H CD 1 ATOM 2638 C CE . LYS B 2 121 ? 16.528 17.487 22.423 1.00 58.59 ? 115 LYS H CE 1 ATOM 2639 N NZ . LYS B 2 121 ? 16.320 18.536 23.403 1.00 58.14 ? 115 LYS H NZ 1 ATOM 2640 N N . THR B 2 122 ? 14.521 15.645 26.615 1.00 32.79 ? 116 THR H N 1 ATOM 2641 C CA . THR B 2 122 ? 14.848 16.591 27.664 1.00 33.41 ? 116 THR H CA 1 ATOM 2642 C C . THR B 2 122 ? 15.528 17.798 26.969 1.00 37.31 ? 116 THR H C 1 ATOM 2643 O O . THR B 2 122 ? 16.376 17.622 26.083 1.00 36.19 ? 116 THR H O 1 ATOM 2644 C CB . THR B 2 122 ? 15.769 15.879 28.777 1.00 34.46 ? 116 THR H CB 1 ATOM 2645 O OG1 . THR B 2 122 ? 16.979 16.614 28.933 1.00 32.52 ? 116 THR H OG1 1 ATOM 2646 C CG2 . THR B 2 122 ? 16.108 14.429 28.450 1.00 36.83 ? 116 THR H CG2 1 ATOM 2647 N N . THR B 2 123 ? 15.136 19.030 27.311 1.00 37.33 ? 117 THR H N 1 ATOM 2648 C CA . THR B 2 123 ? 15.653 20.228 26.686 1.00 31.71 ? 117 THR H CA 1 ATOM 2649 C C . THR B 2 123 ? 16.099 21.241 27.767 1.00 32.51 ? 117 THR H C 1 ATOM 2650 O O . THR B 2 123 ? 15.289 21.504 28.665 1.00 37.80 ? 117 THR H O 1 ATOM 2651 C CB . THR B 2 123 ? 14.501 20.701 25.793 1.00 32.95 ? 117 THR H CB 1 ATOM 2652 O OG1 . THR B 2 123 ? 14.025 19.673 24.900 1.00 34.15 ? 117 THR H OG1 1 ATOM 2653 C CG2 . THR B 2 123 ? 15.020 21.845 24.989 1.00 39.10 ? 117 THR H CG2 1 ATOM 2654 N N . PRO B 2 124 ? 17.326 21.808 27.872 1.00 30.45 ? 118 PRO H N 1 ATOM 2655 C CA . PRO B 2 124 ? 17.706 22.772 28.903 1.00 28.26 ? 118 PRO H CA 1 ATOM 2656 C C . PRO B 2 124 ? 17.029 24.115 28.633 1.00 29.22 ? 118 PRO H C 1 ATOM 2657 O O . PRO B 2 124 ? 16.758 24.407 27.462 1.00 31.01 ? 118 PRO H O 1 ATOM 2658 C CB . PRO B 2 124 ? 19.210 22.811 28.812 1.00 26.29 ? 118 PRO H CB 1 ATOM 2659 C CG . PRO B 2 124 ? 19.441 22.736 27.337 1.00 22.18 ? 118 PRO H CG 1 ATOM 2660 C CD . PRO B 2 124 ? 18.439 21.658 26.929 1.00 28.03 ? 118 PRO H CD 1 ATOM 2661 N N . PRO B 2 125 ? 16.746 24.941 29.658 1.00 24.79 ? 119 PRO H N 1 ATOM 2662 C CA . PRO B 2 125 ? 15.972 26.176 29.562 1.00 22.30 ? 119 PRO H CA 1 ATOM 2663 C C . PRO B 2 125 ? 16.722 27.312 28.906 1.00 24.56 ? 119 PRO H C 1 ATOM 2664 O O . PRO B 2 125 ? 17.952 27.246 28.814 1.00 28.74 ? 119 PRO H O 1 ATOM 2665 C CB . PRO B 2 125 ? 15.651 26.507 30.955 1.00 19.89 ? 119 PRO H CB 1 ATOM 2666 C CG . PRO B 2 125 ? 16.957 26.159 31.642 1.00 14.94 ? 119 PRO H CG 1 ATOM 2667 C CD . PRO B 2 125 ? 17.293 24.830 30.999 1.00 18.50 ? 119 PRO H CD 1 ATOM 2668 N N . SER B 2 126 ? 16.025 28.372 28.497 1.00 25.09 ? 120 SER H N 1 ATOM 2669 C CA . SER B 2 126 ? 16.700 29.607 28.104 1.00 25.96 ? 120 SER H CA 1 ATOM 2670 C C . SER B 2 126 ? 16.119 30.665 29.046 1.00 21.84 ? 120 SER H C 1 ATOM 2671 O O . SER B 2 126 ? 14.914 30.774 29.289 1.00 24.44 ? 120 SER H O 1 ATOM 2672 C CB . SER B 2 126 ? 16.416 29.814 26.615 1.00 31.80 ? 120 SER H CB 1 ATOM 2673 O OG . SER B 2 126 ? 17.209 28.925 25.815 1.00 35.09 ? 120 SER H OG 1 ATOM 2674 N N . VAL B 2 127 ? 16.979 31.389 29.718 1.00 17.37 ? 121 VAL H N 1 ATOM 2675 C CA . VAL B 2 127 ? 16.521 32.182 30.829 1.00 19.36 ? 121 VAL H CA 1 ATOM 2676 C C . VAL B 2 127 ? 16.641 33.600 30.337 1.00 23.45 ? 121 VAL H C 1 ATOM 2677 O O . VAL B 2 127 ? 17.677 33.953 29.776 1.00 30.15 ? 121 VAL H O 1 ATOM 2678 C CB . VAL B 2 127 ? 17.447 31.845 32.015 1.00 21.24 ? 121 VAL H CB 1 ATOM 2679 C CG1 . VAL B 2 127 ? 17.102 32.666 33.217 1.00 20.14 ? 121 VAL H CG1 1 ATOM 2680 C CG2 . VAL B 2 127 ? 17.272 30.397 32.426 1.00 20.11 ? 121 VAL H CG2 1 ATOM 2681 N N . TYR B 2 128 ? 15.608 34.409 30.507 1.00 20.33 ? 122 TYR H N 1 ATOM 2682 C CA . TYR B 2 128 ? 15.605 35.761 30.009 1.00 14.01 ? 122 TYR H CA 1 ATOM 2683 C C . TYR B 2 128 ? 15.310 36.750 31.103 1.00 14.00 ? 122 TYR H C 1 ATOM 2684 O O . TYR B 2 128 ? 14.283 36.638 31.767 1.00 16.58 ? 122 TYR H O 1 ATOM 2685 C CB . TYR B 2 128 ? 14.568 35.880 28.931 1.00 12.55 ? 122 TYR H CB 1 ATOM 2686 C CG . TYR B 2 128 ? 14.867 34.964 27.750 1.00 14.91 ? 122 TYR H CG 1 ATOM 2687 C CD1 . TYR B 2 128 ? 16.073 35.112 27.101 1.00 16.09 ? 122 TYR H CD1 1 ATOM 2688 C CD2 . TYR B 2 128 ? 13.944 34.030 27.291 1.00 16.71 ? 122 TYR H CD2 1 ATOM 2689 C CE1 . TYR B 2 128 ? 16.375 34.344 25.992 1.00 15.64 ? 122 TYR H CE1 1 ATOM 2690 C CE2 . TYR B 2 128 ? 14.233 33.256 26.168 1.00 17.45 ? 122 TYR H CE2 1 ATOM 2691 C CZ . TYR B 2 128 ? 15.459 33.429 25.534 1.00 15.21 ? 122 TYR H CZ 1 ATOM 2692 O OH . TYR B 2 128 ? 15.823 32.691 24.436 1.00 6.89 ? 122 TYR H OH 1 ATOM 2693 N N . PRO B 2 129 ? 16.176 37.717 31.346 1.00 13.39 ? 123 PRO H N 1 ATOM 2694 C CA . PRO B 2 129 ? 16.024 38.750 32.352 1.00 15.28 ? 123 PRO H CA 1 ATOM 2695 C C . PRO B 2 129 ? 14.874 39.649 32.020 1.00 20.91 ? 123 PRO H C 1 ATOM 2696 O O . PRO B 2 129 ? 14.796 40.104 30.876 1.00 22.48 ? 123 PRO H O 1 ATOM 2697 C CB . PRO B 2 129 ? 17.303 39.484 32.342 1.00 17.33 ? 123 PRO H CB 1 ATOM 2698 C CG . PRO B 2 129 ? 17.673 39.373 30.879 1.00 16.87 ? 123 PRO H CG 1 ATOM 2699 C CD . PRO B 2 129 ? 17.388 37.919 30.590 1.00 16.49 ? 123 PRO H CD 1 ATOM 2700 N N . LEU B 2 130 ? 14.025 39.950 32.994 1.00 22.66 ? 124 LEU H N 1 ATOM 2701 C CA . LEU B 2 130 ? 12.852 40.764 32.746 1.00 23.26 ? 124 LEU H CA 1 ATOM 2702 C C . LEU B 2 130 ? 12.998 42.031 33.538 1.00 22.51 ? 124 LEU H C 1 ATOM 2703 O O . LEU B 2 130 ? 12.652 42.133 34.717 1.00 29.71 ? 124 LEU H O 1 ATOM 2704 C CB . LEU B 2 130 ? 11.615 40.004 33.180 1.00 21.75 ? 124 LEU H CB 1 ATOM 2705 C CG . LEU B 2 130 ? 10.641 39.395 32.198 1.00 17.95 ? 124 LEU H CG 1 ATOM 2706 C CD1 . LEU B 2 130 ? 11.355 38.769 31.005 1.00 9.36 ? 124 LEU H CD1 1 ATOM 2707 C CD2 . LEU B 2 130 ? 9.784 38.434 32.991 1.00 15.25 ? 124 LEU H CD2 1 ATOM 2708 N N . ALA B 2 131 ? 13.609 42.996 32.895 1.00 23.62 ? 125 ALA H N 1 ATOM 2709 C CA . ALA B 2 131 ? 13.887 44.272 33.530 1.00 19.48 ? 125 ALA H CA 1 ATOM 2710 C C . ALA B 2 131 ? 12.764 45.205 33.167 1.00 18.60 ? 125 ALA H C 1 ATOM 2711 O O . ALA B 2 131 ? 12.233 45.144 32.061 1.00 23.45 ? 125 ALA H O 1 ATOM 2712 C CB . ALA B 2 131 ? 15.190 44.864 33.025 1.00 15.31 ? 125 ALA H CB 1 ATOM 2713 N N . PRO B 2 132 ? 12.318 46.036 34.075 1.00 21.45 ? 126 PRO H N 1 ATOM 2714 C CA . PRO B 2 132 ? 11.182 46.875 33.868 1.00 26.95 ? 126 PRO H CA 1 ATOM 2715 C C . PRO B 2 132 ? 11.490 47.864 32.783 1.00 39.38 ? 126 PRO H C 1 ATOM 2716 O O . PRO B 2 132 ? 12.617 48.335 32.630 1.00 36.46 ? 126 PRO H O 1 ATOM 2717 C CB . PRO B 2 132 ? 10.954 47.492 35.192 1.00 26.39 ? 126 PRO H CB 1 ATOM 2718 C CG . PRO B 2 132 ? 12.362 47.629 35.702 1.00 27.49 ? 126 PRO H CG 1 ATOM 2719 C CD . PRO B 2 132 ? 12.920 46.271 35.367 1.00 26.21 ? 126 PRO H CD 1 ATOM 2720 N N . GLY B 2 133 ? 10.412 48.094 32.048 1.00 53.74 ? 127 GLY H N 1 ATOM 2721 C CA . GLY B 2 133 ? 10.370 49.045 30.962 1.00 66.07 ? 127 GLY H CA 1 ATOM 2722 C C . GLY B 2 133 ? 9.108 49.799 31.305 1.00 76.17 ? 127 GLY H C 1 ATOM 2723 O O . GLY B 2 133 ? 9.149 50.870 31.910 1.00 80.60 ? 127 GLY H O 1 ATOM 2724 N N . SER B 2 134 ? 7.985 49.152 30.975 1.00 81.16 ? 128 SER H N 1 ATOM 2725 C CA . SER B 2 134 ? 6.664 49.626 31.390 1.00 85.60 ? 128 SER H CA 1 ATOM 2726 C C . SER B 2 134 ? 6.233 51.057 30.987 1.00 85.35 ? 128 SER H C 1 ATOM 2727 O O . SER B 2 134 ? 6.780 51.694 30.075 1.00 81.13 ? 128 SER H O 1 ATOM 2728 C CB . SER B 2 134 ? 6.597 49.447 32.953 1.00 87.94 ? 128 SER H CB 1 ATOM 2729 O OG . SER B 2 134 ? 7.132 48.227 33.490 1.00 83.47 ? 128 SER H OG 1 ATOM 2730 N N . ALA B 2 135 ? 5.062 51.378 31.553 1.00 89.22 ? 129 ALA H N 1 ATOM 2731 C CA . ALA B 2 135 ? 4.481 52.716 31.681 1.00 93.26 ? 129 ALA H CA 1 ATOM 2732 C C . ALA B 2 135 ? 4.434 52.819 33.210 1.00 94.78 ? 129 ALA H C 1 ATOM 2733 O O . ALA B 2 135 ? 4.720 51.842 33.922 1.00 97.31 ? 129 ALA H O 1 ATOM 2734 C CB . ALA B 2 135 ? 3.006 52.892 31.262 1.00 91.59 ? 129 ALA H CB 1 ATOM 2735 N N . ALA B 2 136 ? 3.919 53.956 33.701 1.00 92.41 ? 130 ALA H N 1 ATOM 2736 C CA . ALA B 2 136 ? 3.914 54.344 35.107 1.00 91.31 ? 130 ALA H CA 1 ATOM 2737 C C . ALA B 2 136 ? 5.342 54.709 35.556 1.00 90.63 ? 130 ALA H C 1 ATOM 2738 O O . ALA B 2 136 ? 6.292 54.679 34.769 1.00 91.10 ? 130 ALA H O 1 ATOM 2739 C CB . ALA B 2 136 ? 3.361 53.225 36.023 1.00 92.21 ? 130 ALA H CB 1 ATOM 2740 N N . GLN B 2 137 ? 5.499 55.111 36.815 1.00 89.53 ? 133 GLN H N 1 ATOM 2741 C CA . GLN B 2 137 ? 6.721 55.759 37.291 1.00 87.64 ? 133 GLN H CA 1 ATOM 2742 C C . GLN B 2 137 ? 7.677 54.832 38.063 1.00 86.02 ? 133 GLN H C 1 ATOM 2743 O O . GLN B 2 137 ? 7.940 53.714 37.625 1.00 86.03 ? 133 GLN H O 1 ATOM 2744 C CB . GLN B 2 137 ? 6.214 56.965 38.127 1.00 86.80 ? 133 GLN H CB 1 ATOM 2745 C CG . GLN B 2 137 ? 5.165 57.903 37.484 1.00 81.49 ? 133 GLN H CG 1 ATOM 2746 C CD . GLN B 2 137 ? 5.718 59.171 36.861 1.00 77.57 ? 133 GLN H CD 1 ATOM 2747 O OE1 . GLN B 2 137 ? 6.675 59.186 36.090 1.00 72.78 ? 133 GLN H OE1 1 ATOM 2748 N NE2 . GLN B 2 137 ? 5.095 60.285 37.217 1.00 77.98 ? 133 GLN H NE2 1 ATOM 2749 N N . THR B 2 138 ? 8.202 55.303 39.206 1.00 82.57 ? 134 THR H N 1 ATOM 2750 C CA . THR B 2 138 ? 8.998 54.562 40.179 1.00 75.71 ? 134 THR H CA 1 ATOM 2751 C C . THR B 2 138 ? 8.828 55.393 41.467 1.00 72.63 ? 134 THR H C 1 ATOM 2752 O O . THR B 2 138 ? 8.807 56.638 41.423 1.00 73.07 ? 134 THR H O 1 ATOM 2753 C CB . THR B 2 138 ? 10.501 54.485 39.728 1.00 73.36 ? 134 THR H CB 1 ATOM 2754 O OG1 . THR B 2 138 ? 10.547 53.458 38.754 1.00 71.93 ? 134 THR H OG1 1 ATOM 2755 C CG2 . THR B 2 138 ? 11.504 54.152 40.818 1.00 71.25 ? 134 THR H CG2 1 ATOM 2756 N N . ASN B 2 139 ? 8.584 54.694 42.586 1.00 65.42 ? 135 ASN H N 1 ATOM 2757 C CA . ASN B 2 139 ? 8.483 55.215 43.952 1.00 53.05 ? 135 ASN H CA 1 ATOM 2758 C C . ASN B 2 139 ? 8.168 53.993 44.806 1.00 42.57 ? 135 ASN H C 1 ATOM 2759 O O . ASN B 2 139 ? 7.589 53.045 44.282 1.00 31.70 ? 135 ASN H O 1 ATOM 2760 C CB . ASN B 2 139 ? 7.360 56.285 44.086 1.00 58.82 ? 135 ASN H CB 1 ATOM 2761 C CG . ASN B 2 139 ? 6.012 55.902 44.701 1.00 62.40 ? 135 ASN H CG 1 ATOM 2762 O OD1 . ASN B 2 139 ? 5.442 54.834 44.470 1.00 61.97 ? 135 ASN H OD1 1 ATOM 2763 N ND2 . ASN B 2 139 ? 5.425 56.788 45.503 1.00 62.26 ? 135 ASN H ND2 1 ATOM 2764 N N . SER B 2 140 ? 8.491 53.976 46.105 1.00 42.30 ? 136 SER H N 1 ATOM 2765 C CA . SER B 2 140 ? 8.371 52.802 46.961 1.00 33.71 ? 136 SER H CA 1 ATOM 2766 C C . SER B 2 140 ? 9.082 51.592 46.332 1.00 32.44 ? 136 SER H C 1 ATOM 2767 O O . SER B 2 140 ? 10.272 51.385 46.624 1.00 31.72 ? 136 SER H O 1 ATOM 2768 C CB . SER B 2 140 ? 6.904 52.417 47.193 1.00 37.68 ? 136 SER H CB 1 ATOM 2769 O OG . SER B 2 140 ? 5.986 53.489 47.334 1.00 43.68 ? 136 SER H OG 1 ATOM 2770 N N . MET B 2 141 ? 8.487 50.837 45.366 1.00 30.71 ? 137 MET H N 1 ATOM 2771 C CA . MET B 2 141 ? 8.920 49.507 44.875 1.00 27.27 ? 137 MET H CA 1 ATOM 2772 C C . MET B 2 141 ? 9.065 49.233 43.376 1.00 23.49 ? 137 MET H C 1 ATOM 2773 O O . MET B 2 141 ? 8.486 49.918 42.537 1.00 29.89 ? 137 MET H O 1 ATOM 2774 C CB . MET B 2 141 ? 7.970 48.463 45.466 1.00 25.34 ? 137 MET H CB 1 ATOM 2775 C CG . MET B 2 141 ? 8.428 48.384 46.901 1.00 26.98 ? 137 MET H CG 1 ATOM 2776 S SD . MET B 2 141 ? 7.476 47.478 48.122 1.00 28.16 ? 137 MET H SD 1 ATOM 2777 C CE . MET B 2 141 ? 9.008 46.610 48.383 1.00 23.56 ? 137 MET H CE 1 ATOM 2778 N N . VAL B 2 142 ? 9.831 48.226 42.991 1.00 15.39 ? 138 VAL H N 1 ATOM 2779 C CA . VAL B 2 142 ? 10.071 47.910 41.590 1.00 9.87 ? 138 VAL H CA 1 ATOM 2780 C C . VAL B 2 142 ? 9.883 46.391 41.556 1.00 14.01 ? 138 VAL H C 1 ATOM 2781 O O . VAL B 2 142 ? 9.991 45.709 42.584 1.00 16.79 ? 138 VAL H O 1 ATOM 2782 C CB . VAL B 2 142 ? 11.536 48.347 41.187 1.00 7.75 ? 138 VAL H CB 1 ATOM 2783 C CG1 . VAL B 2 142 ? 12.602 47.424 41.796 1.00 15.44 ? 138 VAL H CG1 1 ATOM 2784 C CG2 . VAL B 2 142 ? 11.733 48.243 39.708 1.00 7.11 ? 138 VAL H CG2 1 ATOM 2785 N N . THR B 2 143 ? 9.605 45.816 40.399 1.00 10.56 ? 139 THR H N 1 ATOM 2786 C CA . THR B 2 143 ? 9.436 44.401 40.310 1.00 7.20 ? 139 THR H CA 1 ATOM 2787 C C . THR B 2 143 ? 10.026 44.042 38.970 1.00 8.14 ? 139 THR H C 1 ATOM 2788 O O . THR B 2 143 ? 9.779 44.745 37.979 1.00 13.54 ? 139 THR H O 1 ATOM 2789 C CB . THR B 2 143 ? 7.919 44.070 40.479 1.00 3.55 ? 139 THR H CB 1 ATOM 2790 O OG1 . THR B 2 143 ? 7.678 43.065 39.514 1.00 3.14 ? 139 THR H OG1 1 ATOM 2791 C CG2 . THR B 2 143 ? 6.970 45.254 40.392 1.00 3.73 ? 139 THR H CG2 1 ATOM 2792 N N . LEU B 2 144 ? 10.873 43.010 39.095 1.00 9.15 ? 140 LEU H N 1 ATOM 2793 C CA . LEU B 2 144 ? 11.711 42.453 38.046 1.00 10.77 ? 140 LEU H CA 1 ATOM 2794 C C . LEU B 2 144 ? 11.392 40.982 37.812 1.00 14.51 ? 140 LEU H C 1 ATOM 2795 O O . LEU B 2 144 ? 10.618 40.380 38.584 1.00 16.45 ? 140 LEU H O 1 ATOM 2796 C CB . LEU B 2 144 ? 13.167 42.498 38.399 1.00 12.53 ? 140 LEU H CB 1 ATOM 2797 C CG . LEU B 2 144 ? 13.864 43.629 39.127 1.00 11.81 ? 140 LEU H CG 1 ATOM 2798 C CD1 . LEU B 2 144 ? 13.486 45.005 38.611 1.00 12.71 ? 140 LEU H CD1 1 ATOM 2799 C CD2 . LEU B 2 144 ? 13.475 43.486 40.554 1.00 14.70 ? 140 LEU H CD2 1 ATOM 2800 N N . GLY B 2 145 ? 11.995 40.325 36.810 1.00 14.30 ? 141 GLY H N 1 ATOM 2801 C CA . GLY B 2 145 ? 11.630 38.939 36.532 1.00 19.61 ? 141 GLY H CA 1 ATOM 2802 C C . GLY B 2 145 ? 12.647 38.099 35.756 1.00 20.49 ? 141 GLY H C 1 ATOM 2803 O O . GLY B 2 145 ? 13.737 38.534 35.387 1.00 19.96 ? 141 GLY H O 1 ATOM 2804 N N . CYS B 2 146 ? 12.233 36.879 35.470 1.00 20.05 ? 142 CYS H N 1 ATOM 2805 C CA . CYS B 2 146 ? 13.037 35.924 34.766 1.00 14.22 ? 142 CYS H CA 1 ATOM 2806 C C . CYS B 2 146 ? 12.041 35.095 33.968 1.00 10.83 ? 142 CYS H C 1 ATOM 2807 O O . CYS B 2 146 ? 11.057 34.627 34.574 1.00 8.26 ? 142 CYS H O 1 ATOM 2808 C CB . CYS B 2 146 ? 13.725 35.154 35.828 1.00 19.19 ? 142 CYS H CB 1 ATOM 2809 S SG . CYS B 2 146 ? 15.497 35.070 35.573 1.00 27.17 ? 142 CYS H SG 1 ATOM 2810 N N . LEU B 2 147 ? 12.179 34.940 32.636 1.00 7.97 ? 143 LEU H N 1 ATOM 2811 C CA . LEU B 2 147 ? 11.274 34.106 31.820 1.00 8.47 ? 143 LEU H CA 1 ATOM 2812 C C . LEU B 2 147 ? 12.142 32.884 31.510 1.00 12.37 ? 143 LEU H C 1 ATOM 2813 O O . LEU B 2 147 ? 13.175 33.013 30.840 1.00 17.99 ? 143 LEU H O 1 ATOM 2814 C CB . LEU B 2 147 ? 10.877 34.852 30.537 1.00 5.32 ? 143 LEU H CB 1 ATOM 2815 C CG . LEU B 2 147 ? 9.543 34.793 29.750 1.00 3.28 ? 143 LEU H CG 1 ATOM 2816 C CD1 . LEU B 2 147 ? 9.755 33.990 28.510 1.00 2.00 ? 143 LEU H CD1 1 ATOM 2817 C CD2 . LEU B 2 147 ? 8.431 34.171 30.548 1.00 2.56 ? 143 LEU H CD2 1 ATOM 2818 N N . VAL B 2 148 ? 11.832 31.728 32.121 1.00 8.17 ? 144 VAL H N 1 ATOM 2819 C CA . VAL B 2 148 ? 12.599 30.509 31.965 1.00 8.45 ? 144 VAL H CA 1 ATOM 2820 C C . VAL B 2 148 ? 11.812 29.797 30.878 1.00 9.12 ? 144 VAL H C 1 ATOM 2821 O O . VAL B 2 148 ? 10.899 29.012 31.151 1.00 14.33 ? 144 VAL H O 1 ATOM 2822 C CB . VAL B 2 148 ? 12.625 29.704 33.300 1.00 2.82 ? 144 VAL H CB 1 ATOM 2823 C CG1 . VAL B 2 148 ? 13.471 28.428 33.227 1.00 2.00 ? 144 VAL H CG1 1 ATOM 2824 C CG2 . VAL B 2 148 ? 13.318 30.542 34.328 1.00 2.00 ? 144 VAL H CG2 1 ATOM 2825 N N . LYS B 2 149 ? 12.153 30.109 29.638 1.00 4.69 ? 145 LYS H N 1 ATOM 2826 C CA . LYS B 2 149 ? 11.430 29.609 28.500 1.00 9.27 ? 145 LYS H CA 1 ATOM 2827 C C . LYS B 2 149 ? 11.987 28.342 27.835 1.00 13.06 ? 145 LYS H C 1 ATOM 2828 O O . LYS B 2 149 ? 13.214 28.205 27.662 1.00 19.82 ? 145 LYS H O 1 ATOM 2829 C CB . LYS B 2 149 ? 11.353 30.801 27.533 1.00 11.96 ? 145 LYS H CB 1 ATOM 2830 C CG . LYS B 2 149 ? 10.443 30.626 26.333 1.00 11.89 ? 145 LYS H CG 1 ATOM 2831 C CD . LYS B 2 149 ? 9.911 31.932 25.809 1.00 14.15 ? 145 LYS H CD 1 ATOM 2832 C CE . LYS B 2 149 ? 8.836 31.690 24.756 1.00 26.86 ? 145 LYS H CE 1 ATOM 2833 N NZ . LYS B 2 149 ? 7.692 30.919 25.252 1.00 31.19 ? 145 LYS H NZ 1 ATOM 2834 N N . GLY B 2 150 ? 11.072 27.422 27.480 1.00 8.16 ? 146 GLY H N 1 ATOM 2835 C CA . GLY B 2 150 ? 11.347 26.229 26.669 1.00 14.82 ? 146 GLY H CA 1 ATOM 2836 C C . GLY B 2 150 ? 12.206 25.080 27.234 1.00 21.96 ? 146 GLY H C 1 ATOM 2837 O O . GLY B 2 150 ? 13.320 24.783 26.774 1.00 22.29 ? 146 GLY H O 1 ATOM 2838 N N . TYR B 2 151 ? 11.682 24.302 28.165 1.00 21.28 ? 147 TYR H N 1 ATOM 2839 C CA . TYR B 2 151 ? 12.504 23.288 28.758 1.00 16.53 ? 147 TYR H CA 1 ATOM 2840 C C . TYR B 2 151 ? 11.723 22.007 28.856 1.00 18.00 ? 147 TYR H C 1 ATOM 2841 O O . TYR B 2 151 ? 10.491 22.055 28.802 1.00 24.63 ? 147 TYR H O 1 ATOM 2842 C CB . TYR B 2 151 ? 12.960 23.800 30.128 1.00 16.54 ? 147 TYR H CB 1 ATOM 2843 C CG . TYR B 2 151 ? 11.932 24.086 31.238 1.00 16.14 ? 147 TYR H CG 1 ATOM 2844 C CD1 . TYR B 2 151 ? 11.313 25.302 31.365 1.00 18.19 ? 147 TYR H CD1 1 ATOM 2845 C CD2 . TYR B 2 151 ? 11.648 23.123 32.163 1.00 17.00 ? 147 TYR H CD2 1 ATOM 2846 C CE1 . TYR B 2 151 ? 10.432 25.541 32.397 1.00 19.25 ? 147 TYR H CE1 1 ATOM 2847 C CE2 . TYR B 2 151 ? 10.770 23.350 33.191 1.00 18.68 ? 147 TYR H CE2 1 ATOM 2848 C CZ . TYR B 2 151 ? 10.160 24.557 33.307 1.00 19.03 ? 147 TYR H CZ 1 ATOM 2849 O OH . TYR B 2 151 ? 9.228 24.745 34.313 1.00 19.99 ? 147 TYR H OH 1 ATOM 2850 N N . PHE B 2 152 ? 12.379 20.851 28.939 1.00 17.54 ? 148 PHE H N 1 ATOM 2851 C CA . PHE B 2 152 ? 11.693 19.600 29.236 1.00 19.68 ? 148 PHE H CA 1 ATOM 2852 C C . PHE B 2 152 ? 12.708 18.754 29.975 1.00 16.27 ? 148 PHE H C 1 ATOM 2853 O O . PHE B 2 152 ? 13.905 18.970 29.816 1.00 11.86 ? 148 PHE H O 1 ATOM 2854 C CB . PHE B 2 152 ? 11.260 18.833 27.989 1.00 25.14 ? 148 PHE H CB 1 ATOM 2855 C CG . PHE B 2 152 ? 10.250 17.701 28.276 1.00 27.47 ? 148 PHE H CG 1 ATOM 2856 C CD1 . PHE B 2 152 ? 8.903 18.008 28.418 1.00 24.68 ? 148 PHE H CD1 1 ATOM 2857 C CD2 . PHE B 2 152 ? 10.666 16.374 28.378 1.00 24.30 ? 148 PHE H CD2 1 ATOM 2858 C CE1 . PHE B 2 152 ? 7.969 17.016 28.655 1.00 19.00 ? 148 PHE H CE1 1 ATOM 2859 C CE2 . PHE B 2 152 ? 9.731 15.389 28.615 1.00 21.08 ? 148 PHE H CE2 1 ATOM 2860 C CZ . PHE B 2 152 ? 8.390 15.711 28.751 1.00 21.87 ? 148 PHE H CZ 1 ATOM 2861 N N . PRO B 2 153 ? 12.367 17.843 30.863 1.00 18.19 ? 149 PRO H N 1 ATOM 2862 C CA . PRO B 2 153 ? 11.138 17.835 31.647 1.00 22.17 ? 149 PRO H CA 1 ATOM 2863 C C . PRO B 2 153 ? 11.211 18.734 32.878 1.00 19.03 ? 149 PRO H C 1 ATOM 2864 O O . PRO B 2 153 ? 12.230 19.395 33.137 1.00 13.06 ? 149 PRO H O 1 ATOM 2865 C CB . PRO B 2 153 ? 10.974 16.374 31.974 1.00 23.72 ? 149 PRO H CB 1 ATOM 2866 C CG . PRO B 2 153 ? 12.412 15.999 32.287 1.00 19.36 ? 149 PRO H CG 1 ATOM 2867 C CD . PRO B 2 153 ? 13.181 16.676 31.160 1.00 18.93 ? 149 PRO H CD 1 ATOM 2868 N N . GLU B 2 154 ? 10.100 18.702 33.618 1.00 19.45 ? 150 GLU H N 1 ATOM 2869 C CA . GLU B 2 154 ? 10.001 19.414 34.886 1.00 20.38 ? 150 GLU H CA 1 ATOM 2870 C C . GLU B 2 154 ? 10.818 18.640 35.868 1.00 17.33 ? 150 GLU H C 1 ATOM 2871 O O . GLU B 2 154 ? 10.730 17.429 35.763 1.00 22.01 ? 150 GLU H O 1 ATOM 2872 C CB . GLU B 2 154 ? 8.587 19.435 35.405 1.00 28.21 ? 150 GLU H CB 1 ATOM 2873 C CG . GLU B 2 154 ? 7.696 20.498 34.779 1.00 30.47 ? 150 GLU H CG 1 ATOM 2874 C CD . GLU B 2 154 ? 7.338 21.604 35.745 1.00 27.29 ? 150 GLU H CD 1 ATOM 2875 O OE1 . GLU B 2 154 ? 8.212 22.451 36.010 1.00 22.50 ? 150 GLU H OE1 1 ATOM 2876 O OE2 . GLU B 2 154 ? 6.186 21.579 36.209 1.00 24.12 ? 150 GLU H OE2 1 ATOM 2877 N N . PRO B 2 155 ? 11.519 19.140 36.869 1.00 24.74 ? 151 PRO H N 1 ATOM 2878 C CA . PRO B 2 155 ? 11.376 20.467 37.431 1.00 26.94 ? 151 PRO H CA 1 ATOM 2879 C C . PRO B 2 155 ? 12.485 21.414 36.983 1.00 27.49 ? 151 PRO H C 1 ATOM 2880 O O . PRO B 2 155 ? 13.412 21.016 36.250 1.00 30.24 ? 151 PRO H O 1 ATOM 2881 C CB . PRO B 2 155 ? 11.376 20.152 38.893 1.00 26.16 ? 151 PRO H CB 1 ATOM 2882 C CG . PRO B 2 155 ? 12.565 19.193 38.977 1.00 28.72 ? 151 PRO H CG 1 ATOM 2883 C CD . PRO B 2 155 ? 12.438 18.360 37.703 1.00 29.32 ? 151 PRO H CD 1 ATOM 2884 N N . VAL B 2 156 ? 12.350 22.647 37.478 1.00 21.96 ? 152 VAL H N 1 ATOM 2885 C CA . VAL B 2 156 ? 13.379 23.647 37.366 1.00 12.82 ? 152 VAL H CA 1 ATOM 2886 C C . VAL B 2 156 ? 13.272 24.430 38.682 1.00 11.16 ? 152 VAL H C 1 ATOM 2887 O O . VAL B 2 156 ? 12.180 24.615 39.228 1.00 8.63 ? 152 VAL H O 1 ATOM 2888 C CB . VAL B 2 156 ? 13.068 24.445 36.108 1.00 11.90 ? 152 VAL H CB 1 ATOM 2889 C CG1 . VAL B 2 156 ? 12.301 25.732 36.304 1.00 12.39 ? 152 VAL H CG1 1 ATOM 2890 C CG2 . VAL B 2 156 ? 14.407 24.752 35.555 1.00 11.56 ? 152 VAL H CG2 1 ATOM 2891 N N . THR B 2 157 ? 14.397 24.822 39.237 1.00 14.98 ? 153 THR H N 1 ATOM 2892 C CA . THR B 2 157 ? 14.509 25.578 40.479 1.00 20.13 ? 153 THR H CA 1 ATOM 2893 C C . THR B 2 157 ? 14.854 27.057 40.246 1.00 18.41 ? 153 THR H C 1 ATOM 2894 O O . THR B 2 157 ? 15.863 27.337 39.575 1.00 20.43 ? 153 THR H O 1 ATOM 2895 C CB . THR B 2 157 ? 15.580 24.827 41.306 1.00 24.74 ? 153 THR H CB 1 ATOM 2896 O OG1 . THR B 2 157 ? 14.855 23.672 41.710 1.00 28.45 ? 153 THR H OG1 1 ATOM 2897 C CG2 . THR B 2 157 ? 16.241 25.596 42.447 1.00 23.96 ? 153 THR H CG2 1 ATOM 2898 N N . VAL B 2 158 ? 14.047 27.994 40.767 1.00 11.53 ? 154 VAL H N 1 ATOM 2899 C CA . VAL B 2 158 ? 14.284 29.418 40.611 1.00 13.24 ? 154 VAL H CA 1 ATOM 2900 C C . VAL B 2 158 ? 14.399 29.906 42.041 1.00 14.92 ? 154 VAL H C 1 ATOM 2901 O O . VAL B 2 158 ? 13.548 29.555 42.867 1.00 21.72 ? 154 VAL H O 1 ATOM 2902 C CB . VAL B 2 158 ? 13.102 30.093 39.895 1.00 15.43 ? 154 VAL H CB 1 ATOM 2903 C CG1 . VAL B 2 158 ? 13.223 31.593 39.926 1.00 21.56 ? 154 VAL H CG1 1 ATOM 2904 C CG2 . VAL B 2 158 ? 13.154 29.773 38.422 1.00 19.44 ? 154 VAL H CG2 1 ATOM 2905 N N . THR B 2 159 ? 15.453 30.683 42.285 1.00 15.33 ? 156 THR H N 1 ATOM 2906 C CA . THR B 2 159 ? 15.848 31.286 43.549 1.00 12.11 ? 156 THR H CA 1 ATOM 2907 C C . THR B 2 159 ? 16.387 32.655 43.128 1.00 15.07 ? 156 THR H C 1 ATOM 2908 O O . THR B 2 159 ? 16.987 32.773 42.045 1.00 18.28 ? 156 THR H O 1 ATOM 2909 C CB . THR B 2 159 ? 16.968 30.440 44.229 1.00 16.24 ? 156 THR H CB 1 ATOM 2910 O OG1 . THR B 2 159 ? 17.268 31.083 45.476 1.00 24.07 ? 156 THR H OG1 1 ATOM 2911 C CG2 . THR B 2 159 ? 18.260 30.337 43.411 1.00 13.43 ? 156 THR H CG2 1 ATOM 2912 N N . TRP B 2 160 ? 16.155 33.698 43.924 1.00 14.27 ? 157 TRP H N 1 ATOM 2913 C CA . TRP B 2 160 ? 16.546 35.049 43.556 1.00 15.98 ? 157 TRP H CA 1 ATOM 2914 C C . TRP B 2 160 ? 17.731 35.366 44.414 1.00 19.51 ? 157 TRP H C 1 ATOM 2915 O O . TRP B 2 160 ? 17.645 35.263 45.644 1.00 23.10 ? 157 TRP H O 1 ATOM 2916 C CB . TRP B 2 160 ? 15.427 36.090 43.852 1.00 15.52 ? 157 TRP H CB 1 ATOM 2917 C CG . TRP B 2 160 ? 14.370 36.028 42.778 1.00 12.92 ? 157 TRP H CG 1 ATOM 2918 C CD1 . TRP B 2 160 ? 13.301 35.186 42.854 1.00 8.31 ? 157 TRP H CD1 1 ATOM 2919 C CD2 . TRP B 2 160 ? 14.447 36.681 41.583 1.00 10.42 ? 157 TRP H CD2 1 ATOM 2920 N NE1 . TRP B 2 160 ? 12.721 35.279 41.685 1.00 7.60 ? 157 TRP H NE1 1 ATOM 2921 C CE2 . TRP B 2 160 ? 13.371 36.162 40.906 1.00 5.65 ? 157 TRP H CE2 1 ATOM 2922 C CE3 . TRP B 2 160 ? 15.286 37.618 41.026 1.00 10.89 ? 157 TRP H CE3 1 ATOM 2923 C CZ2 . TRP B 2 160 ? 13.128 36.591 39.640 1.00 3.44 ? 157 TRP H CZ2 1 ATOM 2924 C CZ3 . TRP B 2 160 ? 15.038 38.044 39.763 1.00 2.75 ? 157 TRP H CZ3 1 ATOM 2925 C CH2 . TRP B 2 160 ? 13.968 37.527 39.087 1.00 4.62 ? 157 TRP H CH2 1 ATOM 2926 N N . ASN B 2 161 ? 18.853 35.709 43.798 1.00 20.05 ? 162 ASN H N 1 ATOM 2927 C CA . ASN B 2 161 ? 20.046 36.102 44.536 1.00 21.68 ? 162 ASN H CA 1 ATOM 2928 C C . ASN B 2 161 ? 20.444 35.042 45.538 1.00 22.51 ? 162 ASN H C 1 ATOM 2929 O O . ASN B 2 161 ? 20.459 35.230 46.761 1.00 14.80 ? 162 ASN H O 1 ATOM 2930 C CB . ASN B 2 161 ? 19.809 37.409 45.280 1.00 24.19 ? 162 ASN H CB 1 ATOM 2931 C CG . ASN B 2 161 ? 20.240 38.676 44.564 1.00 27.12 ? 162 ASN H CG 1 ATOM 2932 O OD1 . ASN B 2 161 ? 20.494 38.740 43.356 1.00 30.26 ? 162 ASN H OD1 1 ATOM 2933 N ND2 . ASN B 2 161 ? 20.336 39.768 45.305 1.00 32.17 ? 162 ASN H ND2 1 ATOM 2934 N N . SER B 2 162 ? 20.559 33.846 44.949 1.00 25.70 ? 163 SER H N 1 ATOM 2935 C CA . SER B 2 162 ? 20.966 32.632 45.638 1.00 26.90 ? 163 SER H CA 1 ATOM 2936 C C . SER B 2 162 ? 20.216 32.234 46.917 1.00 23.74 ? 163 SER H C 1 ATOM 2937 O O . SER B 2 162 ? 20.584 31.222 47.514 1.00 28.75 ? 163 SER H O 1 ATOM 2938 C CB . SER B 2 162 ? 22.481 32.750 45.894 1.00 27.86 ? 163 SER H CB 1 ATOM 2939 O OG . SER B 2 162 ? 23.161 32.797 44.632 1.00 27.99 ? 163 SER H OG 1 ATOM 2940 N N . GLY B 2 163 ? 19.155 32.904 47.363 1.00 17.82 ? 164 GLY H N 1 ATOM 2941 C CA . GLY B 2 163 ? 18.397 32.481 48.522 1.00 18.86 ? 164 GLY H CA 1 ATOM 2942 C C . GLY B 2 163 ? 18.243 33.631 49.487 1.00 19.73 ? 164 GLY H C 1 ATOM 2943 O O . GLY B 2 163 ? 17.465 33.581 50.439 1.00 22.47 ? 164 GLY H O 1 ATOM 2944 N N . SER B 2 164 ? 18.969 34.702 49.238 1.00 18.38 ? 165 SER H N 1 ATOM 2945 C CA . SER B 2 164 ? 18.924 35.855 50.105 1.00 26.05 ? 165 SER H CA 1 ATOM 2946 C C . SER B 2 164 ? 17.697 36.723 49.881 1.00 29.71 ? 165 SER H C 1 ATOM 2947 O O . SER B 2 164 ? 17.367 37.588 50.704 1.00 38.23 ? 165 SER H O 1 ATOM 2948 C CB . SER B 2 164 ? 20.166 36.671 49.863 1.00 30.33 ? 165 SER H CB 1 ATOM 2949 O OG . SER B 2 164 ? 21.232 35.806 49.452 1.00 42.67 ? 165 SER H OG 1 ATOM 2950 N N . LEU B 2 165 ? 16.966 36.542 48.787 1.00 24.14 ? 166 LEU H N 1 ATOM 2951 C CA . LEU B 2 165 ? 15.914 37.471 48.469 1.00 17.40 ? 166 LEU H CA 1 ATOM 2952 C C . LEU B 2 165 ? 14.800 36.510 48.308 1.00 21.41 ? 166 LEU H C 1 ATOM 2953 O O . LEU B 2 165 ? 14.819 35.639 47.453 1.00 26.75 ? 166 LEU H O 1 ATOM 2954 C CB . LEU B 2 165 ? 16.330 38.175 47.202 1.00 14.70 ? 166 LEU H CB 1 ATOM 2955 C CG . LEU B 2 165 ? 15.590 39.315 46.583 1.00 13.17 ? 166 LEU H CG 1 ATOM 2956 C CD1 . LEU B 2 165 ? 14.798 40.077 47.603 1.00 22.28 ? 166 LEU H CD1 1 ATOM 2957 C CD2 . LEU B 2 165 ? 16.607 40.228 45.957 1.00 7.13 ? 166 LEU H CD2 1 ATOM 2958 N N . SER B 2 166 ? 13.913 36.654 49.266 1.00 28.17 ? 167 SER H N 1 ATOM 2959 C CA . SER B 2 166 ? 12.758 35.784 49.431 1.00 31.36 ? 167 SER H CA 1 ATOM 2960 C C . SER B 2 166 ? 11.504 36.570 49.798 1.00 34.87 ? 167 SER H C 1 ATOM 2961 O O . SER B 2 166 ? 10.469 35.974 50.081 1.00 33.73 ? 167 SER H O 1 ATOM 2962 C CB . SER B 2 166 ? 13.102 34.809 50.526 1.00 32.16 ? 167 SER H CB 1 ATOM 2963 O OG . SER B 2 166 ? 13.799 35.579 51.514 1.00 40.58 ? 167 SER H OG 1 ATOM 2964 N N . SER B 2 167 ? 11.626 37.912 49.789 1.00 38.92 ? 168 SER H N 1 ATOM 2965 C CA . SER B 2 167 ? 10.579 38.849 50.164 1.00 40.94 ? 168 SER H CA 1 ATOM 2966 C C . SER B 2 167 ? 9.365 38.710 49.234 1.00 42.62 ? 168 SER H C 1 ATOM 2967 O O . SER B 2 167 ? 8.351 38.074 49.562 1.00 44.50 ? 168 SER H O 1 ATOM 2968 C CB . SER B 2 167 ? 11.150 40.344 50.141 1.00 46.14 ? 168 SER H CB 1 ATOM 2969 O OG . SER B 2 167 ? 11.865 40.877 48.995 1.00 38.81 ? 168 SER H OG 1 ATOM 2970 N N . GLY B 2 168 ? 9.483 39.232 48.012 1.00 37.74 ? 169 GLY H N 1 ATOM 2971 C CA . GLY B 2 168 ? 8.336 39.237 47.155 1.00 27.74 ? 169 GLY H CA 1 ATOM 2972 C C . GLY B 2 168 ? 8.601 38.347 46.006 1.00 21.55 ? 169 GLY H C 1 ATOM 2973 O O . GLY B 2 168 ? 8.762 38.866 44.916 1.00 27.93 ? 169 GLY H O 1 ATOM 2974 N N . VAL B 2 169 ? 8.712 37.053 46.204 1.00 16.88 ? 171 VAL H N 1 ATOM 2975 C CA . VAL B 2 169 ? 8.898 36.207 45.060 1.00 14.04 ? 171 VAL H CA 1 ATOM 2976 C C . VAL B 2 169 ? 7.537 35.598 44.694 1.00 13.36 ? 171 VAL H C 1 ATOM 2977 O O . VAL B 2 169 ? 6.603 35.589 45.500 1.00 14.52 ? 171 VAL H O 1 ATOM 2978 C CB . VAL B 2 169 ? 9.949 35.144 45.408 1.00 9.85 ? 171 VAL H CB 1 ATOM 2979 C CG1 . VAL B 2 169 ? 10.258 34.391 44.116 1.00 14.66 ? 171 VAL H CG1 1 ATOM 2980 C CG2 . VAL B 2 169 ? 11.269 35.752 45.885 1.00 6.41 ? 171 VAL H CG2 1 ATOM 2981 N N . HIS B 2 170 ? 7.265 35.253 43.445 1.00 7.90 ? 172 HIS H N 1 ATOM 2982 C CA . HIS B 2 170 ? 6.135 34.407 43.110 1.00 10.70 ? 172 HIS H CA 1 ATOM 2983 C C . HIS B 2 170 ? 6.753 33.657 41.950 1.00 16.13 ? 172 HIS H C 1 ATOM 2984 O O . HIS B 2 170 ? 7.366 34.324 41.111 1.00 24.46 ? 172 HIS H O 1 ATOM 2985 C CB . HIS B 2 170 ? 4.945 35.141 42.569 1.00 13.54 ? 172 HIS H CB 1 ATOM 2986 C CG . HIS B 2 170 ? 4.409 36.184 43.499 1.00 18.62 ? 172 HIS H CG 1 ATOM 2987 N ND1 . HIS B 2 170 ? 4.845 37.431 43.593 1.00 27.67 ? 172 HIS H ND1 1 ATOM 2988 C CD2 . HIS B 2 170 ? 3.406 35.999 44.396 1.00 18.98 ? 172 HIS H CD2 1 ATOM 2989 C CE1 . HIS B 2 170 ? 4.148 38.027 44.518 1.00 25.18 ? 172 HIS H CE1 1 ATOM 2990 N NE2 . HIS B 2 170 ? 3.292 37.157 44.988 1.00 24.11 ? 172 HIS H NE2 1 ATOM 2991 N N . THR B 2 171 ? 6.755 32.325 41.871 1.00 14.68 ? 173 THR H N 1 ATOM 2992 C CA . THR B 2 171 ? 7.274 31.643 40.691 1.00 11.15 ? 173 THR H CA 1 ATOM 2993 C C . THR B 2 171 ? 6.015 30.965 40.211 1.00 9.38 ? 173 THR H C 1 ATOM 2994 O O . THR B 2 171 ? 5.351 30.252 40.950 1.00 16.54 ? 173 THR H O 1 ATOM 2995 C CB . THR B 2 171 ? 8.362 30.622 41.052 1.00 9.62 ? 173 THR H CB 1 ATOM 2996 O OG1 . THR B 2 171 ? 9.460 31.285 41.721 1.00 13.42 ? 173 THR H OG1 1 ATOM 2997 C CG2 . THR B 2 171 ? 8.834 29.944 39.786 1.00 6.24 ? 173 THR H CG2 1 ATOM 2998 N N . PHE B 2 172 ? 5.583 31.275 39.026 1.00 8.46 ? 174 PHE H N 1 ATOM 2999 C CA . PHE B 2 172 ? 4.314 30.791 38.580 1.00 10.40 ? 174 PHE H CA 1 ATOM 3000 C C . PHE B 2 172 ? 4.441 29.337 38.122 1.00 17.77 ? 174 PHE H C 1 ATOM 3001 O O . PHE B 2 172 ? 5.504 28.928 37.606 1.00 22.49 ? 174 PHE H O 1 ATOM 3002 C CB . PHE B 2 172 ? 3.864 31.700 37.471 1.00 5.74 ? 174 PHE H CB 1 ATOM 3003 C CG . PHE B 2 172 ? 3.721 33.113 37.955 1.00 2.19 ? 174 PHE H CG 1 ATOM 3004 C CD1 . PHE B 2 172 ? 2.533 33.518 38.485 1.00 2.00 ? 174 PHE H CD1 1 ATOM 3005 C CD2 . PHE B 2 172 ? 4.794 33.973 37.870 1.00 5.00 ? 174 PHE H CD2 1 ATOM 3006 C CE1 . PHE B 2 172 ? 2.452 34.808 38.931 1.00 2.00 ? 174 PHE H CE1 1 ATOM 3007 C CE2 . PHE B 2 172 ? 4.690 35.261 38.330 1.00 2.00 ? 174 PHE H CE2 1 ATOM 3008 C CZ . PHE B 2 172 ? 3.518 35.673 38.860 1.00 2.00 ? 174 PHE H CZ 1 ATOM 3009 N N . PRO B 2 173 ? 3.403 28.516 38.333 1.00 16.93 ? 175 PRO H N 1 ATOM 3010 C CA . PRO B 2 173 ? 3.294 27.187 37.770 1.00 18.65 ? 175 PRO H CA 1 ATOM 3011 C C . PRO B 2 173 ? 3.686 27.161 36.281 1.00 26.69 ? 175 PRO H C 1 ATOM 3012 O O . PRO B 2 173 ? 3.311 28.089 35.550 1.00 34.79 ? 175 PRO H O 1 ATOM 3013 C CB . PRO B 2 173 ? 1.860 26.879 38.074 1.00 15.12 ? 175 PRO H CB 1 ATOM 3014 C CG . PRO B 2 173 ? 1.613 27.518 39.407 1.00 14.38 ? 175 PRO H CG 1 ATOM 3015 C CD . PRO B 2 173 ? 2.235 28.853 39.141 1.00 14.74 ? 175 PRO H CD 1 ATOM 3016 N N . ALA B 2 174 ? 4.414 26.151 35.764 1.00 25.68 ? 176 ALA H N 1 ATOM 3017 C CA . ALA B 2 174 ? 4.793 26.150 34.346 1.00 22.35 ? 176 ALA H CA 1 ATOM 3018 C C . ALA B 2 174 ? 3.708 25.648 33.418 1.00 20.12 ? 176 ALA H C 1 ATOM 3019 O O . ALA B 2 174 ? 3.071 24.648 33.764 1.00 22.68 ? 176 ALA H O 1 ATOM 3020 C CB . ALA B 2 174 ? 5.991 25.259 34.099 1.00 22.34 ? 176 ALA H CB 1 ATOM 3021 N N . VAL B 2 175 ? 3.480 26.277 32.259 1.00 22.33 ? 177 VAL H N 1 ATOM 3022 C CA . VAL B 2 175 ? 2.526 25.768 31.249 1.00 18.58 ? 177 VAL H CA 1 ATOM 3023 C C . VAL B 2 175 ? 3.277 25.122 30.104 1.00 21.15 ? 177 VAL H C 1 ATOM 3024 O O . VAL B 2 175 ? 4.447 25.438 29.825 1.00 18.91 ? 177 VAL H O 1 ATOM 3025 C CB . VAL B 2 175 ? 1.670 26.843 30.620 1.00 13.45 ? 177 VAL H CB 1 ATOM 3026 C CG1 . VAL B 2 175 ? 0.738 27.449 31.642 1.00 13.43 ? 177 VAL H CG1 1 ATOM 3027 C CG2 . VAL B 2 175 ? 2.574 27.942 30.111 1.00 16.60 ? 177 VAL H CG2 1 ATOM 3028 N N . LEU B 2 176 ? 2.601 24.246 29.381 1.00 26.16 ? 178 LEU H N 1 ATOM 3029 C CA . LEU B 2 176 ? 3.284 23.501 28.330 1.00 34.32 ? 178 LEU H CA 1 ATOM 3030 C C . LEU B 2 176 ? 2.875 24.012 26.974 1.00 38.44 ? 178 LEU H C 1 ATOM 3031 O O . LEU B 2 176 ? 1.681 24.087 26.704 1.00 45.56 ? 178 LEU H O 1 ATOM 3032 C CB . LEU B 2 176 ? 2.928 22.020 28.472 1.00 35.31 ? 178 LEU H CB 1 ATOM 3033 C CG . LEU B 2 176 ? 3.617 20.825 27.804 1.00 32.38 ? 178 LEU H CG 1 ATOM 3034 C CD1 . LEU B 2 176 ? 5.063 20.603 28.234 1.00 28.56 ? 178 LEU H CD1 1 ATOM 3035 C CD2 . LEU B 2 176 ? 2.856 19.608 28.268 1.00 32.51 ? 178 LEU H CD2 1 ATOM 3036 N N . GLN B 2 177 ? 3.832 24.449 26.155 1.00 46.15 ? 179 GLN H N 1 ATOM 3037 C CA . GLN B 2 177 ? 3.556 24.846 24.783 1.00 47.59 ? 179 GLN H CA 1 ATOM 3038 C C . GLN B 2 177 ? 3.635 23.639 23.850 1.00 50.28 ? 179 GLN H C 1 ATOM 3039 O O . GLN B 2 177 ? 2.763 22.772 23.853 1.00 50.50 ? 179 GLN H O 1 ATOM 3040 C CB . GLN B 2 177 ? 4.552 25.908 24.347 1.00 48.54 ? 179 GLN H CB 1 ATOM 3041 C CG . GLN B 2 177 ? 4.056 27.229 24.885 1.00 53.48 ? 179 GLN H CG 1 ATOM 3042 C CD . GLN B 2 177 ? 4.761 28.472 24.348 1.00 57.70 ? 179 GLN H CD 1 ATOM 3043 O OE1 . GLN B 2 177 ? 5.989 28.625 24.376 1.00 57.08 ? 179 GLN H OE1 1 ATOM 3044 N NE2 . GLN B 2 177 ? 3.942 29.399 23.847 1.00 53.89 ? 179 GLN H NE2 1 ATOM 3045 N N . SER B 2 178 ? 4.677 23.436 23.063 1.00 55.27 ? 180 SER H N 1 ATOM 3046 C CA . SER B 2 178 ? 4.711 22.350 22.096 1.00 59.45 ? 180 SER H CA 1 ATOM 3047 C C . SER B 2 178 ? 5.755 21.399 22.661 1.00 57.43 ? 180 SER H C 1 ATOM 3048 O O . SER B 2 178 ? 6.952 21.621 22.449 1.00 56.31 ? 180 SER H O 1 ATOM 3049 C CB . SER B 2 178 ? 5.101 23.002 20.773 1.00 67.89 ? 180 SER H CB 1 ATOM 3050 O OG . SER B 2 178 ? 4.602 24.349 20.708 1.00 71.67 ? 180 SER H OG 1 ATOM 3051 N N . ASP B 2 179 ? 5.305 20.405 23.444 1.00 49.36 ? 183 ASP H N 1 ATOM 3052 C CA . ASP B 2 179 ? 6.174 19.509 24.196 1.00 47.65 ? 183 ASP H CA 1 ATOM 3053 C C . ASP B 2 179 ? 7.280 20.240 24.983 1.00 43.61 ? 183 ASP H C 1 ATOM 3054 O O . ASP B 2 179 ? 8.305 19.640 25.285 1.00 46.30 ? 183 ASP H O 1 ATOM 3055 C CB . ASP B 2 179 ? 6.815 18.418 23.244 1.00 56.26 ? 183 ASP H CB 1 ATOM 3056 C CG . ASP B 2 179 ? 7.862 18.670 22.116 1.00 63.55 ? 183 ASP H CG 1 ATOM 3057 O OD1 . ASP B 2 179 ? 8.756 19.515 22.231 1.00 65.09 ? 183 ASP H OD1 1 ATOM 3058 O OD2 . ASP B 2 179 ? 7.812 17.963 21.100 1.00 65.18 ? 183 ASP H OD2 1 ATOM 3059 N N . LEU B 2 180 ? 7.109 21.499 25.422 1.00 36.91 ? 184 LEU H N 1 ATOM 3060 C CA . LEU B 2 180 ? 8.153 22.272 26.093 1.00 31.96 ? 184 LEU H CA 1 ATOM 3061 C C . LEU B 2 180 ? 7.521 23.234 27.093 1.00 25.23 ? 184 LEU H C 1 ATOM 3062 O O . LEU B 2 180 ? 6.550 23.926 26.784 1.00 25.59 ? 184 LEU H O 1 ATOM 3063 C CB . LEU B 2 180 ? 8.943 23.044 25.035 1.00 36.85 ? 184 LEU H CB 1 ATOM 3064 C CG . LEU B 2 180 ? 10.446 22.825 24.793 1.00 36.72 ? 184 LEU H CG 1 ATOM 3065 C CD1 . LEU B 2 180 ? 10.770 21.462 24.206 1.00 39.20 ? 184 LEU H CD1 1 ATOM 3066 C CD2 . LEU B 2 180 ? 10.889 23.827 23.756 1.00 37.99 ? 184 LEU H CD2 1 ATOM 3067 N N . TYR B 2 181 ? 8.033 23.275 28.299 1.00 16.26 ? 185 TYR H N 1 ATOM 3068 C CA . TYR B 2 181 ? 7.510 24.070 29.389 1.00 17.29 ? 185 TYR H CA 1 ATOM 3069 C C . TYR B 2 181 ? 8.070 25.476 29.416 1.00 20.28 ? 185 TYR H C 1 ATOM 3070 O O . TYR B 2 181 ? 9.226 25.646 29.024 1.00 22.47 ? 185 TYR H O 1 ATOM 3071 C CB . TYR B 2 181 ? 7.875 23.482 30.730 1.00 25.04 ? 185 TYR H CB 1 ATOM 3072 C CG . TYR B 2 181 ? 7.133 22.244 31.135 1.00 26.54 ? 185 TYR H CG 1 ATOM 3073 C CD1 . TYR B 2 181 ? 5.831 22.382 31.531 1.00 28.66 ? 185 TYR H CD1 1 ATOM 3074 C CD2 . TYR B 2 181 ? 7.729 21.011 31.043 1.00 26.07 ? 185 TYR H CD2 1 ATOM 3075 C CE1 . TYR B 2 181 ? 5.101 21.257 31.821 1.00 30.35 ? 185 TYR H CE1 1 ATOM 3076 C CE2 . TYR B 2 181 ? 6.990 19.886 31.338 1.00 28.25 ? 185 TYR H CE2 1 ATOM 3077 C CZ . TYR B 2 181 ? 5.682 20.025 31.721 1.00 26.88 ? 185 TYR H CZ 1 ATOM 3078 O OH . TYR B 2 181 ? 4.912 18.924 31.979 1.00 32.39 ? 185 TYR H OH 1 ATOM 3079 N N . THR B 2 182 ? 7.315 26.459 29.932 1.00 20.08 ? 186 THR H N 1 ATOM 3080 C CA . THR B 2 182 ? 7.747 27.844 30.142 1.00 15.98 ? 186 THR H CA 1 ATOM 3081 C C . THR B 2 182 ? 7.183 28.322 31.493 1.00 15.86 ? 186 THR H C 1 ATOM 3082 O O . THR B 2 182 ? 5.986 28.116 31.772 1.00 14.00 ? 186 THR H O 1 ATOM 3083 C CB . THR B 2 182 ? 7.217 28.785 29.005 1.00 19.68 ? 186 THR H CB 1 ATOM 3084 O OG1 . THR B 2 182 ? 7.817 28.322 27.788 1.00 16.62 ? 186 THR H OG1 1 ATOM 3085 C CG2 . THR B 2 182 ? 7.507 30.284 29.262 1.00 17.52 ? 186 THR H CG2 1 ATOM 3086 N N . LEU B 2 183 ? 8.030 28.885 32.371 1.00 13.86 ? 187 LEU H N 1 ATOM 3087 C CA . LEU B 2 183 ? 7.568 29.488 33.611 1.00 16.93 ? 187 LEU H CA 1 ATOM 3088 C C . LEU B 2 183 ? 8.302 30.794 33.869 1.00 14.73 ? 187 LEU H C 1 ATOM 3089 O O . LEU B 2 183 ? 9.252 31.129 33.171 1.00 21.64 ? 187 LEU H O 1 ATOM 3090 C CB . LEU B 2 183 ? 7.779 28.549 34.809 1.00 17.99 ? 187 LEU H CB 1 ATOM 3091 C CG . LEU B 2 183 ? 9.092 28.172 35.446 1.00 13.69 ? 187 LEU H CG 1 ATOM 3092 C CD1 . LEU B 2 183 ? 9.675 29.251 36.339 1.00 14.59 ? 187 LEU H CD1 1 ATOM 3093 C CD2 . LEU B 2 183 ? 8.780 27.087 36.413 1.00 10.75 ? 187 LEU H CD2 1 ATOM 3094 N N . SER B 2 184 ? 7.975 31.528 34.902 1.00 10.87 ? 188 SER H N 1 ATOM 3095 C CA . SER B 2 184 ? 8.552 32.827 35.135 1.00 11.70 ? 188 SER H CA 1 ATOM 3096 C C . SER B 2 184 ? 8.319 33.053 36.617 1.00 15.69 ? 188 SER H C 1 ATOM 3097 O O . SER B 2 184 ? 7.426 32.436 37.240 1.00 7.35 ? 188 SER H O 1 ATOM 3098 C CB . SER B 2 184 ? 7.796 33.866 34.335 1.00 18.51 ? 188 SER H CB 1 ATOM 3099 O OG . SER B 2 184 ? 6.364 33.733 34.533 1.00 22.36 ? 188 SER H OG 1 ATOM 3100 N N . SER B 2 185 ? 9.127 33.972 37.125 1.00 14.43 ? 189 SER H N 1 ATOM 3101 C CA . SER B 2 185 ? 9.119 34.318 38.516 1.00 11.67 ? 189 SER H CA 1 ATOM 3102 C C . SER B 2 185 ? 9.243 35.819 38.512 1.00 12.80 ? 189 SER H C 1 ATOM 3103 O O . SER B 2 185 ? 9.976 36.366 37.669 1.00 17.27 ? 189 SER H O 1 ATOM 3104 C CB . SER B 2 185 ? 10.315 33.659 39.197 1.00 8.62 ? 189 SER H CB 1 ATOM 3105 O OG . SER B 2 185 ? 10.316 33.852 40.600 1.00 9.84 ? 189 SER H OG 1 ATOM 3106 N N . SER B 2 186 ? 8.541 36.477 39.410 1.00 8.01 ? 190 SER H N 1 ATOM 3107 C CA . SER B 2 186 ? 8.659 37.902 39.531 1.00 14.74 ? 190 SER H CA 1 ATOM 3108 C C . SER B 2 186 ? 9.203 38.164 40.913 1.00 15.48 ? 190 SER H C 1 ATOM 3109 O O . SER B 2 186 ? 8.889 37.349 41.798 1.00 20.01 ? 190 SER H O 1 ATOM 3110 C CB . SER B 2 186 ? 7.309 38.547 39.435 1.00 22.09 ? 190 SER H CB 1 ATOM 3111 O OG . SER B 2 186 ? 6.417 38.245 40.522 1.00 29.95 ? 190 SER H OG 1 ATOM 3112 N N . VAL B 2 187 ? 9.921 39.265 41.164 1.00 13.61 ? 191 VAL H N 1 ATOM 3113 C CA . VAL B 2 187 ? 10.296 39.597 42.526 1.00 13.24 ? 191 VAL H CA 1 ATOM 3114 C C . VAL B 2 187 ? 10.156 41.094 42.819 1.00 12.76 ? 191 VAL H C 1 ATOM 3115 O O . VAL B 2 187 ? 10.403 41.912 41.941 1.00 14.21 ? 191 VAL H O 1 ATOM 3116 C CB . VAL B 2 187 ? 11.755 39.099 42.799 1.00 12.34 ? 191 VAL H CB 1 ATOM 3117 C CG1 . VAL B 2 187 ? 12.752 39.963 42.084 1.00 18.30 ? 191 VAL H CG1 1 ATOM 3118 C CG2 . VAL B 2 187 ? 12.088 39.168 44.276 1.00 13.66 ? 191 VAL H CG2 1 ATOM 3119 N N . THR B 2 188 ? 9.797 41.495 44.034 1.00 17.14 ? 192 THR H N 1 ATOM 3120 C CA . THR B 2 188 ? 9.763 42.884 44.421 1.00 14.74 ? 192 THR H CA 1 ATOM 3121 C C . THR B 2 188 ? 10.743 43.347 45.466 1.00 13.81 ? 192 THR H C 1 ATOM 3122 O O . THR B 2 188 ? 10.789 42.966 46.630 1.00 22.30 ? 192 THR H O 1 ATOM 3123 C CB . THR B 2 188 ? 8.357 43.149 44.816 1.00 18.00 ? 192 THR H CB 1 ATOM 3124 O OG1 . THR B 2 188 ? 7.952 43.654 43.553 1.00 24.56 ? 192 THR H OG1 1 ATOM 3125 C CG2 . THR B 2 188 ? 8.011 44.079 45.983 1.00 20.20 ? 192 THR H CG2 1 ATOM 3126 N N . VAL B 2 189 ? 11.499 44.246 44.921 1.00 13.50 ? 193 VAL H N 1 ATOM 3127 C CA . VAL B 2 189 ? 12.594 44.900 45.568 1.00 18.92 ? 193 VAL H CA 1 ATOM 3128 C C . VAL B 2 189 ? 12.212 46.378 45.810 1.00 27.58 ? 193 VAL H C 1 ATOM 3129 O O . VAL B 2 189 ? 11.517 46.985 44.975 1.00 30.56 ? 193 VAL H O 1 ATOM 3130 C CB . VAL B 2 189 ? 13.712 44.649 44.566 1.00 20.23 ? 193 VAL H CB 1 ATOM 3131 C CG1 . VAL B 2 189 ? 14.805 45.690 44.705 1.00 20.97 ? 193 VAL H CG1 1 ATOM 3132 C CG2 . VAL B 2 189 ? 14.225 43.219 44.762 1.00 13.60 ? 193 VAL H CG2 1 ATOM 3133 N N . PRO B 2 190 ? 12.636 47.059 46.891 1.00 24.54 ? 194 PRO H N 1 ATOM 3134 C CA . PRO B 2 190 ? 12.567 48.496 47.053 1.00 18.09 ? 194 PRO H CA 1 ATOM 3135 C C . PRO B 2 190 ? 13.205 49.171 45.880 1.00 19.35 ? 194 PRO H C 1 ATOM 3136 O O . PRO B 2 190 ? 14.209 48.662 45.370 1.00 14.80 ? 194 PRO H O 1 ATOM 3137 C CB . PRO B 2 190 ? 13.301 48.778 48.306 1.00 15.47 ? 194 PRO H CB 1 ATOM 3138 C CG . PRO B 2 190 ? 12.938 47.605 49.126 1.00 18.31 ? 194 PRO H CG 1 ATOM 3139 C CD . PRO B 2 190 ? 13.156 46.486 48.110 1.00 23.73 ? 194 PRO H CD 1 ATOM 3140 N N . SER B 2 191 ? 12.641 50.342 45.556 1.00 20.39 ? 195 SER H N 1 ATOM 3141 C CA . SER B 2 191 ? 13.122 51.145 44.461 1.00 17.63 ? 195 SER H CA 1 ATOM 3142 C C . SER B 2 191 ? 14.563 51.498 44.714 1.00 18.21 ? 195 SER H C 1 ATOM 3143 O O . SER B 2 191 ? 15.325 51.423 43.759 1.00 23.31 ? 195 SER H O 1 ATOM 3144 C CB . SER B 2 191 ? 12.319 52.415 44.329 1.00 20.21 ? 195 SER H CB 1 ATOM 3145 O OG . SER B 2 191 ? 10.961 52.171 43.955 1.00 22.09 ? 195 SER H OG 1 ATOM 3146 N N . SER B 2 192 ? 14.979 51.834 45.950 1.00 19.72 ? 196 SER H N 1 ATOM 3147 C CA . SER B 2 192 ? 16.400 52.091 46.240 1.00 22.35 ? 196 SER H CA 1 ATOM 3148 C C . SER B 2 192 ? 17.364 50.992 45.708 1.00 29.29 ? 196 SER H C 1 ATOM 3149 O O . SER B 2 192 ? 18.287 51.388 44.979 1.00 34.54 ? 196 SER H O 1 ATOM 3150 C CB . SER B 2 192 ? 16.595 52.265 47.768 1.00 15.14 ? 196 SER H CB 1 ATOM 3151 O OG . SER B 2 192 ? 15.410 52.759 48.396 1.00 19.27 ? 196 SER H OG 1 ATOM 3152 N N . PRO B 2 193 ? 17.216 49.655 45.955 1.00 31.16 ? 198 PRO H N 1 ATOM 3153 C CA . PRO B 2 193 ? 18.113 48.626 45.492 1.00 28.29 ? 198 PRO H CA 1 ATOM 3154 C C . PRO B 2 193 ? 18.317 48.348 44.052 1.00 29.31 ? 198 PRO H C 1 ATOM 3155 O O . PRO B 2 193 ? 19.358 48.795 43.586 1.00 30.37 ? 198 PRO H O 1 ATOM 3156 C CB . PRO B 2 193 ? 17.688 47.374 46.184 1.00 33.48 ? 198 PRO H CB 1 ATOM 3157 C CG . PRO B 2 193 ? 17.321 47.856 47.543 1.00 34.22 ? 198 PRO H CG 1 ATOM 3158 C CD . PRO B 2 193 ? 16.524 49.059 47.104 1.00 35.34 ? 198 PRO H CD 1 ATOM 3159 N N . ARG B 2 194 ? 17.380 47.705 43.332 1.00 35.03 ? 199 ARG H N 1 ATOM 3160 C CA . ARG B 2 194 ? 17.674 47.164 41.985 1.00 38.46 ? 199 ARG H CA 1 ATOM 3161 C C . ARG B 2 194 ? 18.492 48.020 41.051 1.00 46.03 ? 199 ARG H C 1 ATOM 3162 O O . ARG B 2 194 ? 19.305 47.417 40.356 1.00 54.41 ? 199 ARG H O 1 ATOM 3163 C CB . ARG B 2 194 ? 16.450 46.805 41.150 1.00 24.43 ? 199 ARG H CB 1 ATOM 3164 C CG . ARG B 2 194 ? 16.717 45.835 39.986 1.00 21.65 ? 199 ARG H CG 1 ATOM 3165 C CD . ARG B 2 194 ? 17.493 46.143 38.694 1.00 15.05 ? 199 ARG H CD 1 ATOM 3166 N NE . ARG B 2 194 ? 16.785 46.826 37.636 1.00 22.44 ? 199 ARG H NE 1 ATOM 3167 C CZ . ARG B 2 194 ? 15.838 47.769 37.783 1.00 27.92 ? 199 ARG H CZ 1 ATOM 3168 N NH1 . ARG B 2 194 ? 15.476 48.357 38.911 1.00 24.72 ? 199 ARG H NH1 1 ATOM 3169 N NH2 . ARG B 2 194 ? 15.278 48.262 36.688 1.00 33.86 ? 199 ARG H NH2 1 ATOM 3170 N N . PRO B 2 195 ? 18.389 49.339 40.934 1.00 45.85 ? 200 PRO H N 1 ATOM 3171 C CA . PRO B 2 195 ? 19.431 50.075 40.261 1.00 41.57 ? 200 PRO H CA 1 ATOM 3172 C C . PRO B 2 195 ? 20.854 49.726 40.758 1.00 36.25 ? 200 PRO H C 1 ATOM 3173 O O . PRO B 2 195 ? 21.621 49.053 40.071 1.00 24.61 ? 200 PRO H O 1 ATOM 3174 C CB . PRO B 2 195 ? 18.968 51.509 40.501 1.00 48.95 ? 200 PRO H CB 1 ATOM 3175 C CG . PRO B 2 195 ? 17.454 51.448 40.620 1.00 49.72 ? 200 PRO H CG 1 ATOM 3176 C CD . PRO B 2 195 ? 17.309 50.192 41.442 1.00 45.56 ? 200 PRO H CD 1 ATOM 3177 N N . SER B 2 196 ? 21.144 50.162 41.982 1.00 33.88 ? 202 SER H N 1 ATOM 3178 C CA . SER B 2 196 ? 22.476 50.164 42.523 1.00 40.76 ? 202 SER H CA 1 ATOM 3179 C C . SER B 2 196 ? 22.929 48.837 43.070 1.00 44.21 ? 202 SER H C 1 ATOM 3180 O O . SER B 2 196 ? 24.067 48.414 42.868 1.00 50.07 ? 202 SER H O 1 ATOM 3181 C CB . SER B 2 196 ? 22.533 51.223 43.607 1.00 43.81 ? 202 SER H CB 1 ATOM 3182 O OG . SER B 2 196 ? 21.462 51.059 44.526 1.00 44.41 ? 202 SER H OG 1 ATOM 3183 N N . GLU B 2 197 ? 22.090 48.248 43.911 1.00 43.57 ? 203 GLU H N 1 ATOM 3184 C CA . GLU B 2 197 ? 22.309 46.898 44.379 1.00 39.34 ? 203 GLU H CA 1 ATOM 3185 C C . GLU B 2 197 ? 21.996 46.027 43.192 1.00 35.71 ? 203 GLU H C 1 ATOM 3186 O O . GLU B 2 197 ? 21.517 46.558 42.196 1.00 34.22 ? 203 GLU H O 1 ATOM 3187 C CB . GLU B 2 197 ? 21.354 46.569 45.476 1.00 45.38 ? 203 GLU H CB 1 ATOM 3188 C CG . GLU B 2 197 ? 21.809 47.093 46.817 1.00 53.66 ? 203 GLU H CG 1 ATOM 3189 C CD . GLU B 2 197 ? 23.117 46.429 47.204 1.00 59.45 ? 203 GLU H CD 1 ATOM 3190 O OE1 . GLU B 2 197 ? 23.117 45.214 47.412 1.00 60.96 ? 203 GLU H OE1 1 ATOM 3191 O OE2 . GLU B 2 197 ? 24.135 47.126 47.272 1.00 65.67 ? 203 GLU H OE2 1 ATOM 3192 N N . THR B 2 198 ? 22.220 44.725 43.173 1.00 36.42 ? 204 THR H N 1 ATOM 3193 C CA . THR B 2 198 ? 21.750 43.985 42.018 1.00 40.20 ? 204 THR H CA 1 ATOM 3194 C C . THR B 2 198 ? 21.090 42.703 42.390 1.00 35.14 ? 204 THR H C 1 ATOM 3195 O O . THR B 2 198 ? 21.452 42.104 43.398 1.00 35.68 ? 204 THR H O 1 ATOM 3196 C CB . THR B 2 198 ? 22.864 43.661 41.038 1.00 46.59 ? 204 THR H CB 1 ATOM 3197 O OG1 . THR B 2 198 ? 24.100 43.740 41.757 1.00 48.04 ? 204 THR H OG1 1 ATOM 3198 C CG2 . THR B 2 198 ? 22.718 44.542 39.775 1.00 48.93 ? 204 THR H CG2 1 ATOM 3199 N N . VAL B 2 199 ? 20.083 42.402 41.574 1.00 28.72 ? 205 VAL H N 1 ATOM 3200 C CA . VAL B 2 199 ? 19.239 41.253 41.738 1.00 23.03 ? 205 VAL H CA 1 ATOM 3201 C C . VAL B 2 199 ? 19.625 40.303 40.576 1.00 30.39 ? 205 VAL H C 1 ATOM 3202 O O . VAL B 2 199 ? 19.942 40.782 39.466 1.00 29.82 ? 205 VAL H O 1 ATOM 3203 C CB . VAL B 2 199 ? 17.787 41.825 41.719 1.00 18.38 ? 205 VAL H CB 1 ATOM 3204 C CG1 . VAL B 2 199 ? 16.764 40.724 41.992 1.00 15.71 ? 205 VAL H CG1 1 ATOM 3205 C CG2 . VAL B 2 199 ? 17.642 42.903 42.814 1.00 12.63 ? 205 VAL H CG2 1 ATOM 3206 N N . THR B 2 200 ? 19.616 38.970 40.821 1.00 28.94 ? 206 THR H N 1 ATOM 3207 C CA . THR B 2 200 ? 20.000 37.907 39.887 1.00 22.10 ? 206 THR H CA 1 ATOM 3208 C C . THR B 2 200 ? 19.054 36.684 39.940 1.00 23.17 ? 206 THR H C 1 ATOM 3209 O O . THR B 2 200 ? 18.736 36.301 41.073 1.00 19.96 ? 206 THR H O 1 ATOM 3210 C CB . THR B 2 200 ? 21.403 37.441 40.246 1.00 21.64 ? 206 THR H CB 1 ATOM 3211 O OG1 . THR B 2 200 ? 22.159 38.608 40.554 1.00 28.62 ? 206 THR H OG1 1 ATOM 3212 C CG2 . THR B 2 200 ? 22.033 36.606 39.139 1.00 22.03 ? 206 THR H CG2 1 ATOM 3213 N N . CYS B 2 201 ? 18.536 36.049 38.860 1.00 19.35 ? 208 CYS H N 1 ATOM 3214 C CA . CYS B 2 201 ? 17.840 34.774 38.993 1.00 18.70 ? 208 CYS H CA 1 ATOM 3215 C C . CYS B 2 201 ? 18.823 33.673 38.676 1.00 21.37 ? 208 CYS H C 1 ATOM 3216 O O . CYS B 2 201 ? 19.688 33.757 37.798 1.00 22.86 ? 208 CYS H O 1 ATOM 3217 C CB . CYS B 2 201 ? 16.733 34.483 38.035 1.00 14.75 ? 208 CYS H CB 1 ATOM 3218 S SG . CYS B 2 201 ? 16.359 35.970 37.146 1.00 32.84 ? 208 CYS H SG 1 ATOM 3219 N N . ASN B 2 202 ? 18.692 32.588 39.409 1.00 22.65 ? 209 ASN H N 1 ATOM 3220 C CA . ASN B 2 202 ? 19.593 31.483 39.262 1.00 18.51 ? 209 ASN H CA 1 ATOM 3221 C C . ASN B 2 202 ? 18.597 30.395 38.973 1.00 18.56 ? 209 ASN H C 1 ATOM 3222 O O . ASN B 2 202 ? 17.766 30.148 39.857 1.00 20.39 ? 209 ASN H O 1 ATOM 3223 C CB . ASN B 2 202 ? 20.288 31.264 40.574 1.00 20.96 ? 209 ASN H CB 1 ATOM 3224 C CG . ASN B 2 202 ? 20.696 32.533 41.308 1.00 24.63 ? 209 ASN H CG 1 ATOM 3225 O OD1 . ASN B 2 202 ? 20.063 32.976 42.265 1.00 30.98 ? 209 ASN H OD1 1 ATOM 3226 N ND2 . ASN B 2 202 ? 21.758 33.220 40.940 1.00 26.89 ? 209 ASN H ND2 1 ATOM 3227 N N . VAL B 2 203 ? 18.616 29.828 37.757 1.00 14.82 ? 210 VAL H N 1 ATOM 3228 C CA . VAL B 2 203 ? 17.690 28.785 37.295 1.00 13.14 ? 210 VAL H CA 1 ATOM 3229 C C . VAL B 2 203 ? 18.453 27.492 37.150 1.00 15.02 ? 210 VAL H C 1 ATOM 3230 O O . VAL B 2 203 ? 19.353 27.357 36.312 1.00 20.30 ? 210 VAL H O 1 ATOM 3231 C CB . VAL B 2 203 ? 17.097 29.014 35.901 1.00 16.06 ? 210 VAL H CB 1 ATOM 3232 C CG1 . VAL B 2 203 ? 16.047 27.928 35.619 1.00 18.55 ? 210 VAL H CG1 1 ATOM 3233 C CG2 . VAL B 2 203 ? 16.548 30.411 35.803 1.00 15.84 ? 210 VAL H CG2 1 ATOM 3234 N N . ALA B 2 204 ? 18.072 26.489 37.887 1.00 12.73 ? 211 ALA H N 1 ATOM 3235 C CA . ALA B 2 204 ? 18.801 25.257 37.805 1.00 6.49 ? 211 ALA H CA 1 ATOM 3236 C C . ALA B 2 204 ? 17.896 24.245 37.180 1.00 3.20 ? 211 ALA H C 1 ATOM 3237 O O . ALA B 2 204 ? 16.845 23.948 37.748 1.00 5.83 ? 211 ALA H O 1 ATOM 3238 C CB . ALA B 2 204 ? 19.164 24.811 39.193 1.00 9.57 ? 211 ALA H CB 1 ATOM 3239 N N . HIS B 2 205 ? 18.194 23.707 36.023 1.00 7.65 ? 212 HIS H N 1 ATOM 3240 C CA . HIS B 2 205 ? 17.365 22.647 35.486 1.00 14.64 ? 212 HIS H CA 1 ATOM 3241 C C . HIS B 2 205 ? 18.054 21.311 35.757 1.00 23.65 ? 212 HIS H C 1 ATOM 3242 O O . HIS B 2 205 ? 18.869 20.884 34.933 1.00 33.30 ? 212 HIS H O 1 ATOM 3243 C CB . HIS B 2 205 ? 17.177 22.882 33.999 1.00 11.59 ? 212 HIS H CB 1 ATOM 3244 C CG . HIS B 2 205 ? 16.425 21.806 33.237 1.00 11.69 ? 212 HIS H CG 1 ATOM 3245 N ND1 . HIS B 2 205 ? 16.782 21.281 32.085 1.00 16.19 ? 212 HIS H ND1 1 ATOM 3246 C CD2 . HIS B 2 205 ? 15.238 21.234 33.593 1.00 16.22 ? 212 HIS H CD2 1 ATOM 3247 C CE1 . HIS B 2 205 ? 15.861 20.426 31.729 1.00 15.90 ? 212 HIS H CE1 1 ATOM 3248 N NE2 . HIS B 2 205 ? 14.935 20.406 32.644 1.00 14.93 ? 212 HIS H NE2 1 ATOM 3249 N N . PRO B 2 206 ? 17.720 20.566 36.817 1.00 26.50 ? 213 PRO H N 1 ATOM 3250 C CA . PRO B 2 206 ? 18.387 19.340 37.221 1.00 27.99 ? 213 PRO H CA 1 ATOM 3251 C C . PRO B 2 206 ? 18.578 18.339 36.066 1.00 26.41 ? 213 PRO H C 1 ATOM 3252 O O . PRO B 2 206 ? 19.719 18.003 35.757 1.00 28.49 ? 213 PRO H O 1 ATOM 3253 C CB . PRO B 2 206 ? 17.506 18.799 38.352 1.00 33.40 ? 213 PRO H CB 1 ATOM 3254 C CG . PRO B 2 206 ? 16.682 19.966 38.852 1.00 32.52 ? 213 PRO H CG 1 ATOM 3255 C CD . PRO B 2 206 ? 16.432 20.648 37.514 1.00 33.22 ? 213 PRO H CD 1 ATOM 3256 N N . ALA B 2 207 ? 17.565 17.903 35.307 1.00 21.55 ? 214 ALA H N 1 ATOM 3257 C CA . ALA B 2 207 ? 17.760 16.934 34.229 1.00 25.65 ? 214 ALA H CA 1 ATOM 3258 C C . ALA B 2 207 ? 18.688 17.255 33.022 1.00 34.56 ? 214 ALA H C 1 ATOM 3259 O O . ALA B 2 207 ? 18.515 16.736 31.911 1.00 37.38 ? 214 ALA H O 1 ATOM 3260 C CB . ALA B 2 207 ? 16.369 16.571 33.722 1.00 22.11 ? 214 ALA H CB 1 ATOM 3261 N N . SER B 2 208 ? 19.647 18.184 33.159 1.00 37.20 ? 215 SER H N 1 ATOM 3262 C CA . SER B 2 208 ? 20.675 18.488 32.169 1.00 38.82 ? 215 SER H CA 1 ATOM 3263 C C . SER B 2 208 ? 21.813 19.240 32.864 1.00 43.65 ? 215 SER H C 1 ATOM 3264 O O . SER B 2 208 ? 22.715 19.778 32.211 1.00 48.60 ? 215 SER H O 1 ATOM 3265 C CB . SER B 2 208 ? 20.105 19.353 31.027 1.00 33.94 ? 215 SER H CB 1 ATOM 3266 O OG . SER B 2 208 ? 19.094 20.231 31.497 1.00 27.49 ? 215 SER H OG 1 ATOM 3267 N N . SER B 2 209 ? 21.826 19.265 34.206 1.00 43.37 ? 216 SER H N 1 ATOM 3268 C CA . SER B 2 209 ? 22.807 20.000 35.001 1.00 46.34 ? 216 SER H CA 1 ATOM 3269 C C . SER B 2 209 ? 22.964 21.440 34.550 1.00 44.03 ? 216 SER H C 1 ATOM 3270 O O . SER B 2 209 ? 23.998 22.084 34.748 1.00 51.42 ? 216 SER H O 1 ATOM 3271 C CB . SER B 2 209 ? 24.163 19.321 34.920 1.00 52.21 ? 216 SER H CB 1 ATOM 3272 O OG . SER B 2 209 ? 23.992 17.943 34.589 1.00 63.22 ? 216 SER H OG 1 ATOM 3273 N N . THR B 2 210 ? 21.939 21.973 33.907 1.00 34.28 ? 217 THR H N 1 ATOM 3274 C CA . THR B 2 210 ? 22.021 23.320 33.460 1.00 28.12 ? 217 THR H CA 1 ATOM 3275 C C . THR B 2 210 ? 21.833 24.080 34.741 1.00 29.22 ? 217 THR H C 1 ATOM 3276 O O . THR B 2 210 ? 21.043 23.697 35.614 1.00 28.83 ? 217 THR H O 1 ATOM 3277 C CB . THR B 2 210 ? 20.900 23.669 32.550 1.00 31.71 ? 217 THR H CB 1 ATOM 3278 O OG1 . THR B 2 210 ? 20.163 22.495 32.184 1.00 29.57 ? 217 THR H OG1 1 ATOM 3279 C CG2 . THR B 2 210 ? 21.493 24.406 31.374 1.00 35.68 ? 217 THR H CG2 1 ATOM 3280 N N . LYS B 2 211 ? 22.654 25.086 34.884 1.00 28.79 ? 218 LYS H N 1 ATOM 3281 C CA . LYS B 2 211 ? 22.533 26.026 35.963 1.00 28.93 ? 218 LYS H CA 1 ATOM 3282 C C . LYS B 2 211 ? 22.753 27.295 35.162 1.00 31.41 ? 218 LYS H C 1 ATOM 3283 O O . LYS B 2 211 ? 23.629 27.365 34.287 1.00 34.11 ? 218 LYS H O 1 ATOM 3284 C CB . LYS B 2 211 ? 23.628 25.807 36.989 1.00 32.26 ? 218 LYS H CB 1 ATOM 3285 C CG . LYS B 2 211 ? 23.355 24.580 37.885 1.00 43.97 ? 218 LYS H CG 1 ATOM 3286 C CD . LYS B 2 211 ? 24.546 24.048 38.729 1.00 52.49 ? 218 LYS H CD 1 ATOM 3287 C CE . LYS B 2 211 ? 25.445 22.940 38.076 1.00 58.92 ? 218 LYS H CE 1 ATOM 3288 N NZ . LYS B 2 211 ? 26.365 23.365 37.012 1.00 58.84 ? 218 LYS H NZ 1 ATOM 3289 N N . VAL B 2 212 ? 21.894 28.286 35.312 1.00 28.21 ? 219 VAL H N 1 ATOM 3290 C CA . VAL B 2 212 ? 22.090 29.542 34.622 1.00 22.23 ? 219 VAL H CA 1 ATOM 3291 C C . VAL B 2 212 ? 21.978 30.592 35.696 1.00 20.20 ? 219 VAL H C 1 ATOM 3292 O O . VAL B 2 212 ? 21.242 30.401 36.673 1.00 26.06 ? 219 VAL H O 1 ATOM 3293 C CB . VAL B 2 212 ? 21.003 29.758 33.568 1.00 19.63 ? 219 VAL H CB 1 ATOM 3294 C CG1 . VAL B 2 212 ? 21.127 31.139 32.965 1.00 24.64 ? 219 VAL H CG1 1 ATOM 3295 C CG2 . VAL B 2 212 ? 21.187 28.802 32.422 1.00 16.89 ? 219 VAL H CG2 1 ATOM 3296 N N . ASP B 2 213 ? 22.747 31.659 35.615 1.00 17.53 ? 220 ASP H N 1 ATOM 3297 C CA . ASP B 2 213 ? 22.457 32.782 36.475 1.00 23.32 ? 220 ASP H CA 1 ATOM 3298 C C . ASP B 2 213 ? 22.299 33.943 35.522 1.00 27.14 ? 220 ASP H C 1 ATOM 3299 O O . ASP B 2 213 ? 23.073 34.024 34.563 1.00 30.27 ? 220 ASP H O 1 ATOM 3300 C CB . ASP B 2 213 ? 23.578 33.104 37.412 1.00 25.46 ? 220 ASP H CB 1 ATOM 3301 C CG . ASP B 2 213 ? 23.800 32.147 38.567 1.00 26.90 ? 220 ASP H CG 1 ATOM 3302 O OD1 . ASP B 2 213 ? 23.098 31.152 38.721 1.00 26.97 ? 220 ASP H OD1 1 ATOM 3303 O OD2 . ASP B 2 213 ? 24.697 32.435 39.348 1.00 33.09 ? 220 ASP H OD2 1 ATOM 3304 N N . LYS B 2 214 ? 21.293 34.793 35.692 1.00 27.58 ? 221 LYS H N 1 ATOM 3305 C CA . LYS B 2 214 ? 21.094 35.943 34.838 1.00 29.23 ? 221 LYS H CA 1 ATOM 3306 C C . LYS B 2 214 ? 20.811 37.085 35.780 1.00 30.46 ? 221 LYS H C 1 ATOM 3307 O O . LYS B 2 214 ? 20.017 36.951 36.711 1.00 28.94 ? 221 LYS H O 1 ATOM 3308 C CB . LYS B 2 214 ? 19.924 35.735 33.888 1.00 30.16 ? 221 LYS H CB 1 ATOM 3309 C CG . LYS B 2 214 ? 20.314 34.874 32.684 1.00 32.69 ? 221 LYS H CG 1 ATOM 3310 C CD . LYS B 2 214 ? 21.070 35.718 31.674 1.00 36.34 ? 221 LYS H CD 1 ATOM 3311 C CE . LYS B 2 214 ? 21.643 34.877 30.555 1.00 43.51 ? 221 LYS H CE 1 ATOM 3312 N NZ . LYS B 2 214 ? 20.591 34.207 29.803 1.00 54.23 ? 221 LYS H NZ 1 ATOM 3313 N N . LYS B 2 215 ? 21.621 38.123 35.554 1.00 31.14 ? 222 LYS H N 1 ATOM 3314 C CA . LYS B 2 215 ? 21.693 39.361 36.316 1.00 30.61 ? 222 LYS H CA 1 ATOM 3315 C C . LYS B 2 215 ? 20.682 40.284 35.731 1.00 30.63 ? 222 LYS H C 1 ATOM 3316 O O . LYS B 2 215 ? 20.650 40.414 34.509 1.00 38.33 ? 222 LYS H O 1 ATOM 3317 C CB . LYS B 2 215 ? 23.025 40.017 36.142 1.00 32.71 ? 222 LYS H CB 1 ATOM 3318 C CG . LYS B 2 215 ? 23.268 41.259 36.979 1.00 35.00 ? 222 LYS H CG 1 ATOM 3319 C CD . LYS B 2 215 ? 24.767 41.548 36.909 1.00 44.26 ? 222 LYS H CD 1 ATOM 3320 C CE . LYS B 2 215 ? 25.641 40.389 37.470 1.00 49.18 ? 222 LYS H CE 1 ATOM 3321 N NZ . LYS B 2 215 ? 27.043 40.521 37.094 1.00 48.51 ? 222 LYS H NZ 1 ATOM 3322 N N . ILE B 2 216 ? 19.890 40.976 36.511 1.00 26.77 ? 223 ILE H N 1 ATOM 3323 C CA . ILE B 2 216 ? 18.933 41.830 35.879 1.00 22.04 ? 223 ILE H CA 1 ATOM 3324 C C . ILE B 2 216 ? 19.569 43.181 36.003 1.00 24.27 ? 223 ILE H C 1 ATOM 3325 O O . ILE B 2 216 ? 19.897 43.707 37.069 1.00 25.13 ? 223 ILE H O 1 ATOM 3326 C CB . ILE B 2 216 ? 17.623 41.597 36.623 1.00 20.78 ? 223 ILE H CB 1 ATOM 3327 C CG1 . ILE B 2 216 ? 17.067 40.283 36.063 1.00 20.99 ? 223 ILE H CG1 1 ATOM 3328 C CG2 . ILE B 2 216 ? 16.606 42.704 36.424 1.00 22.21 ? 223 ILE H CG2 1 ATOM 3329 C CD1 . ILE B 2 216 ? 16.442 39.396 37.146 1.00 16.20 ? 223 ILE H CD1 1 ATOM 3330 N N . VAL B 2 217 ? 19.865 43.590 34.778 1.00 31.47 ? 226 VAL H N 1 ATOM 3331 C CA . VAL B 2 217 ? 20.494 44.870 34.467 1.00 34.74 ? 226 VAL H CA 1 ATOM 3332 C C . VAL B 2 217 ? 19.490 45.664 33.614 1.00 36.32 ? 226 VAL H C 1 ATOM 3333 O O . VAL B 2 217 ? 18.711 44.987 32.927 1.00 39.17 ? 226 VAL H O 1 ATOM 3334 C CB . VAL B 2 217 ? 21.844 44.529 33.756 1.00 31.95 ? 226 VAL H CB 1 ATOM 3335 C CG1 . VAL B 2 217 ? 21.640 43.756 32.458 1.00 28.39 ? 226 VAL H CG1 1 ATOM 3336 C CG2 . VAL B 2 217 ? 22.587 45.821 33.537 1.00 31.70 ? 226 VAL H CG2 1 ATOM 3337 N N . PRO B 2 218 ? 19.370 47.007 33.712 1.00 37.36 ? 227 PRO H N 1 ATOM 3338 C CA . PRO B 2 218 ? 18.393 47.811 32.941 1.00 41.56 ? 227 PRO H CA 1 ATOM 3339 C C . PRO B 2 218 ? 18.662 48.105 31.441 1.00 46.87 ? 227 PRO H C 1 ATOM 3340 O O . PRO B 2 218 ? 17.712 48.395 30.684 1.00 42.49 ? 227 PRO H O 1 ATOM 3341 C CB . PRO B 2 218 ? 18.253 49.083 33.783 1.00 33.48 ? 227 PRO H CB 1 ATOM 3342 C CG . PRO B 2 218 ? 18.725 48.657 35.137 1.00 30.93 ? 227 PRO H CG 1 ATOM 3343 C CD . PRO B 2 218 ? 19.919 47.806 34.798 1.00 31.04 ? 227 PRO H CD 1 ATOM 3344 N N . ASP C 1 1 ? -38.327 21.646 -1.127 1.00 53.50 ? 1 ASP M N 1 ATOM 3345 C CA . ASP C 1 1 ? -37.830 22.806 -0.413 1.00 47.24 ? 1 ASP M CA 1 ATOM 3346 C C . ASP C 1 1 ? -38.361 23.876 -1.333 1.00 39.99 ? 1 ASP M C 1 ATOM 3347 O O . ASP C 1 1 ? -37.732 24.162 -2.344 1.00 39.85 ? 1 ASP M O 1 ATOM 3348 C CB . ASP C 1 1 ? -36.311 22.795 -0.396 1.00 46.34 ? 1 ASP M CB 1 ATOM 3349 C CG . ASP C 1 1 ? -35.815 23.997 0.378 1.00 50.88 ? 1 ASP M CG 1 ATOM 3350 O OD1 . ASP C 1 1 ? -35.872 23.929 1.604 1.00 52.72 ? 1 ASP M OD1 1 ATOM 3351 O OD2 . ASP C 1 1 ? -35.409 24.991 -0.233 1.00 51.26 ? 1 ASP M OD2 1 ATOM 3352 N N . VAL C 1 2 ? -39.552 24.378 -1.109 1.00 33.84 ? 2 VAL M N 1 ATOM 3353 C CA . VAL C 1 2 ? -40.101 25.266 -2.128 1.00 38.35 ? 2 VAL M CA 1 ATOM 3354 C C . VAL C 1 2 ? -39.671 26.683 -1.773 1.00 40.19 ? 2 VAL M C 1 ATOM 3355 O O . VAL C 1 2 ? -39.659 26.981 -0.574 1.00 44.77 ? 2 VAL M O 1 ATOM 3356 C CB . VAL C 1 2 ? -41.681 24.995 -2.197 1.00 34.73 ? 2 VAL M CB 1 ATOM 3357 C CG1 . VAL C 1 2 ? -42.240 24.361 -0.904 1.00 29.08 ? 2 VAL M CG1 1 ATOM 3358 C CG2 . VAL C 1 2 ? -42.363 26.300 -2.563 1.00 27.18 ? 2 VAL M CG2 1 ATOM 3359 N N . LEU C 1 3 ? -39.198 27.526 -2.684 1.00 36.05 ? 3 LEU M N 1 ATOM 3360 C CA . LEU C 1 3 ? -38.780 28.802 -2.196 1.00 41.29 ? 3 LEU M CA 1 ATOM 3361 C C . LEU C 1 3 ? -39.696 29.921 -2.597 1.00 47.04 ? 3 LEU M C 1 ATOM 3362 O O . LEU C 1 3 ? -40.063 30.132 -3.754 1.00 50.61 ? 3 LEU M O 1 ATOM 3363 C CB . LEU C 1 3 ? -37.318 29.064 -2.621 1.00 44.55 ? 3 LEU M CB 1 ATOM 3364 C CG . LEU C 1 3 ? -36.253 28.440 -1.616 1.00 47.40 ? 3 LEU M CG 1 ATOM 3365 C CD1 . LEU C 1 3 ? -34.866 28.975 -1.918 1.00 43.80 ? 3 LEU M CD1 1 ATOM 3366 C CD2 . LEU C 1 3 ? -36.483 28.876 -0.164 1.00 45.48 ? 3 LEU M CD2 1 ATOM 3367 N N . MET C 1 4 ? -40.174 30.468 -1.469 1.00 46.81 ? 4 MET M N 1 ATOM 3368 C CA . MET C 1 4 ? -41.038 31.633 -1.423 1.00 38.05 ? 4 MET M CA 1 ATOM 3369 C C . MET C 1 4 ? -40.293 32.940 -1.640 1.00 35.62 ? 4 MET M C 1 ATOM 3370 O O . MET C 1 4 ? -39.202 33.182 -1.104 1.00 39.35 ? 4 MET M O 1 ATOM 3371 C CB . MET C 1 4 ? -41.746 31.719 -0.084 1.00 35.04 ? 4 MET M CB 1 ATOM 3372 C CG . MET C 1 4 ? -43.142 31.190 -0.242 1.00 35.76 ? 4 MET M CG 1 ATOM 3373 S SD . MET C 1 4 ? -43.325 29.506 0.380 1.00 40.19 ? 4 MET M SD 1 ATOM 3374 C CE . MET C 1 4 ? -44.687 30.178 1.269 1.00 41.04 ? 4 MET M CE 1 ATOM 3375 N N . THR C 1 5 ? -40.893 33.816 -2.422 1.00 28.95 ? 5 THR M N 1 ATOM 3376 C CA . THR C 1 5 ? -40.303 35.088 -2.710 1.00 31.49 ? 5 THR M CA 1 ATOM 3377 C C . THR C 1 5 ? -41.254 36.182 -2.253 1.00 37.94 ? 5 THR M C 1 ATOM 3378 O O . THR C 1 5 ? -42.412 36.226 -2.686 1.00 48.27 ? 5 THR M O 1 ATOM 3379 C CB . THR C 1 5 ? -40.049 35.131 -4.206 1.00 30.00 ? 5 THR M CB 1 ATOM 3380 O OG1 . THR C 1 5 ? -39.290 33.961 -4.503 1.00 33.12 ? 5 THR M OG1 1 ATOM 3381 C CG2 . THR C 1 5 ? -39.339 36.403 -4.649 1.00 29.78 ? 5 THR M CG2 1 ATOM 3382 N N . GLN C 1 6 ? -40.830 37.077 -1.355 1.00 37.04 ? 6 GLN M N 1 ATOM 3383 C CA . GLN C 1 6 ? -41.703 38.159 -0.938 1.00 28.08 ? 6 GLN M CA 1 ATOM 3384 C C . GLN C 1 6 ? -41.171 39.431 -1.522 1.00 25.89 ? 6 GLN M C 1 ATOM 3385 O O . GLN C 1 6 ? -39.967 39.649 -1.716 1.00 22.98 ? 6 GLN M O 1 ATOM 3386 C CB . GLN C 1 6 ? -41.748 38.371 0.545 1.00 26.07 ? 6 GLN M CB 1 ATOM 3387 C CG . GLN C 1 6 ? -42.581 37.367 1.284 1.00 24.54 ? 6 GLN M CG 1 ATOM 3388 C CD . GLN C 1 6 ? -42.337 37.559 2.761 1.00 25.95 ? 6 GLN M CD 1 ATOM 3389 O OE1 . GLN C 1 6 ? -41.827 36.675 3.448 1.00 26.30 ? 6 GLN M OE1 1 ATOM 3390 N NE2 . GLN C 1 6 ? -42.595 38.728 3.308 1.00 25.35 ? 6 GLN M NE2 1 ATOM 3391 N N . THR C 1 7 ? -42.204 40.172 -1.839 1.00 26.44 ? 7 THR M N 1 ATOM 3392 C CA . THR C 1 7 ? -42.107 41.477 -2.415 1.00 27.10 ? 7 THR M CA 1 ATOM 3393 C C . THR C 1 7 ? -43.166 42.279 -1.666 1.00 31.75 ? 7 THR M C 1 ATOM 3394 O O . THR C 1 7 ? -44.297 41.804 -1.463 1.00 35.84 ? 7 THR M O 1 ATOM 3395 C CB . THR C 1 7 ? -42.388 41.343 -3.920 1.00 25.34 ? 7 THR M CB 1 ATOM 3396 O OG1 . THR C 1 7 ? -43.448 40.423 -4.142 1.00 26.09 ? 7 THR M OG1 1 ATOM 3397 C CG2 . THR C 1 7 ? -41.151 40.846 -4.636 1.00 26.41 ? 7 THR M CG2 1 ATOM 3398 N N . PRO C 1 8 ? -42.900 43.488 -1.191 1.00 32.56 ? 8 PRO M N 1 ATOM 3399 C CA . PRO C 1 8 ? -41.652 44.217 -1.305 1.00 32.01 ? 8 PRO M CA 1 ATOM 3400 C C . PRO C 1 8 ? -40.665 43.737 -0.275 1.00 31.00 ? 8 PRO M C 1 ATOM 3401 O O . PRO C 1 8 ? -40.858 42.698 0.344 1.00 33.40 ? 8 PRO M O 1 ATOM 3402 C CB . PRO C 1 8 ? -42.040 45.651 -1.084 1.00 32.91 ? 8 PRO M CB 1 ATOM 3403 C CG . PRO C 1 8 ? -43.538 45.637 -1.187 1.00 36.64 ? 8 PRO M CG 1 ATOM 3404 C CD . PRO C 1 8 ? -43.877 44.327 -0.524 1.00 34.53 ? 8 PRO M CD 1 ATOM 3405 N N . LEU C 1 9 ? -39.602 44.501 -0.105 1.00 25.93 ? 9 LEU M N 1 ATOM 3406 C CA . LEU C 1 9 ? -38.746 44.203 0.986 1.00 25.63 ? 9 LEU M CA 1 ATOM 3407 C C . LEU C 1 9 ? -38.836 45.369 1.948 1.00 28.37 ? 9 LEU M C 1 ATOM 3408 O O . LEU C 1 9 ? -38.708 45.140 3.149 1.00 36.13 ? 9 LEU M O 1 ATOM 3409 C CB . LEU C 1 9 ? -37.344 43.970 0.464 1.00 30.29 ? 9 LEU M CB 1 ATOM 3410 C CG . LEU C 1 9 ? -36.848 42.509 0.261 1.00 35.95 ? 9 LEU M CG 1 ATOM 3411 C CD1 . LEU C 1 9 ? -37.885 41.458 0.678 1.00 36.98 ? 9 LEU M CD1 1 ATOM 3412 C CD2 . LEU C 1 9 ? -36.570 42.298 -1.216 1.00 37.87 ? 9 LEU M CD2 1 ATOM 3413 N N . SER C 1 10 ? -39.036 46.625 1.568 1.00 23.68 ? 10 SER M N 1 ATOM 3414 C CA . SER C 1 10 ? -39.253 47.660 2.570 1.00 22.11 ? 10 SER M CA 1 ATOM 3415 C C . SER C 1 10 ? -40.624 48.201 2.178 1.00 26.54 ? 10 SER M C 1 ATOM 3416 O O . SER C 1 10 ? -41.068 47.949 1.049 1.00 35.26 ? 10 SER M O 1 ATOM 3417 C CB . SER C 1 10 ? -38.175 48.745 2.479 1.00 21.86 ? 10 SER M CB 1 ATOM 3418 O OG . SER C 1 10 ? -38.167 49.688 3.556 1.00 23.53 ? 10 SER M OG 1 ATOM 3419 N N . LEU C 1 11 ? -41.361 48.903 3.019 1.00 22.68 ? 11 LEU M N 1 ATOM 3420 C CA . LEU C 1 11 ? -42.681 49.337 2.636 1.00 23.61 ? 11 LEU M CA 1 ATOM 3421 C C . LEU C 1 11 ? -43.030 50.576 3.452 1.00 25.73 ? 11 LEU M C 1 ATOM 3422 O O . LEU C 1 11 ? -43.532 50.499 4.581 1.00 28.63 ? 11 LEU M O 1 ATOM 3423 C CB . LEU C 1 11 ? -43.640 48.185 2.892 1.00 22.91 ? 11 LEU M CB 1 ATOM 3424 C CG . LEU C 1 11 ? -45.058 48.389 2.416 1.00 31.48 ? 11 LEU M CG 1 ATOM 3425 C CD1 . LEU C 1 11 ? -45.167 48.136 0.942 1.00 36.53 ? 11 LEU M CD1 1 ATOM 3426 C CD2 . LEU C 1 11 ? -45.957 47.373 3.061 1.00 37.82 ? 11 LEU M CD2 1 ATOM 3427 N N . PRO C 1 12 ? -42.704 51.764 2.960 1.00 21.31 ? 12 PRO M N 1 ATOM 3428 C CA . PRO C 1 12 ? -43.105 53.014 3.563 1.00 22.79 ? 12 PRO M CA 1 ATOM 3429 C C . PRO C 1 12 ? -44.602 53.154 3.418 1.00 30.21 ? 12 PRO M C 1 ATOM 3430 O O . PRO C 1 12 ? -45.050 53.000 2.280 1.00 40.37 ? 12 PRO M O 1 ATOM 3431 C CB . PRO C 1 12 ? -42.327 54.009 2.797 1.00 21.87 ? 12 PRO M CB 1 ATOM 3432 C CG . PRO C 1 12 ? -41.144 53.233 2.304 1.00 19.98 ? 12 PRO M CG 1 ATOM 3433 C CD . PRO C 1 12 ? -41.829 51.994 1.835 1.00 16.78 ? 12 PRO M CD 1 ATOM 3434 N N . VAL C 1 13 ? -45.443 53.329 4.452 1.00 32.72 ? 13 VAL M N 1 ATOM 3435 C CA . VAL C 1 13 ? -46.874 53.616 4.259 1.00 26.49 ? 13 VAL M CA 1 ATOM 3436 C C . VAL C 1 13 ? -47.193 54.597 5.362 1.00 23.62 ? 13 VAL M C 1 ATOM 3437 O O . VAL C 1 13 ? -46.643 54.549 6.470 1.00 21.84 ? 13 VAL M O 1 ATOM 3438 C CB . VAL C 1 13 ? -47.872 52.385 4.386 1.00 25.75 ? 13 VAL M CB 1 ATOM 3439 C CG1 . VAL C 1 13 ? -47.217 51.113 3.857 1.00 24.61 ? 13 VAL M CG1 1 ATOM 3440 C CG2 . VAL C 1 13 ? -48.275 52.116 5.793 1.00 27.37 ? 13 VAL M CG2 1 ATOM 3441 N N . SER C 1 14 ? -48.030 55.559 5.025 1.00 24.40 ? 14 SER M N 1 ATOM 3442 C CA . SER C 1 14 ? -48.355 56.596 5.985 1.00 22.92 ? 14 SER M CA 1 ATOM 3443 C C . SER C 1 14 ? -49.398 55.984 6.845 1.00 17.84 ? 14 SER M C 1 ATOM 3444 O O . SER C 1 14 ? -50.137 55.124 6.373 1.00 16.65 ? 14 SER M O 1 ATOM 3445 C CB . SER C 1 14 ? -48.953 57.850 5.357 1.00 19.72 ? 14 SER M CB 1 ATOM 3446 O OG . SER C 1 14 ? -47.903 58.507 4.679 1.00 20.74 ? 14 SER M OG 1 ATOM 3447 N N . LEU C 1 15 ? -49.406 56.420 8.092 1.00 17.34 ? 15 LEU M N 1 ATOM 3448 C CA . LEU C 1 15 ? -50.412 55.967 9.007 1.00 19.33 ? 15 LEU M CA 1 ATOM 3449 C C . LEU C 1 15 ? -51.707 56.336 8.331 1.00 21.53 ? 15 LEU M C 1 ATOM 3450 O O . LEU C 1 15 ? -51.833 57.402 7.739 1.00 32.13 ? 15 LEU M O 1 ATOM 3451 C CB . LEU C 1 15 ? -50.234 56.669 10.346 1.00 13.77 ? 15 LEU M CB 1 ATOM 3452 C CG . LEU C 1 15 ? -48.952 56.320 11.110 1.00 13.32 ? 15 LEU M CG 1 ATOM 3453 C CD1 . LEU C 1 15 ? -49.079 56.824 12.543 1.00 2.00 ? 15 LEU M CD1 1 ATOM 3454 C CD2 . LEU C 1 15 ? -48.737 54.788 11.134 1.00 11.99 ? 15 LEU M CD2 1 ATOM 3455 N N . GLY C 1 16 ? -52.537 55.335 8.178 1.00 24.47 ? 16 GLY M N 1 ATOM 3456 C CA . GLY C 1 16 ? -53.809 55.534 7.549 1.00 28.43 ? 16 GLY M CA 1 ATOM 3457 C C . GLY C 1 16 ? -53.860 54.720 6.297 1.00 29.95 ? 16 GLY M C 1 ATOM 3458 O O . GLY C 1 16 ? -54.883 54.100 6.017 1.00 41.38 ? 16 GLY M O 1 ATOM 3459 N N . ASP C 1 17 ? -52.771 54.724 5.551 1.00 24.58 ? 17 ASP M N 1 ATOM 3460 C CA . ASP C 1 17 ? -52.685 53.946 4.334 1.00 29.76 ? 17 ASP M CA 1 ATOM 3461 C C . ASP C 1 17 ? -52.914 52.474 4.537 1.00 28.47 ? 17 ASP M C 1 ATOM 3462 O O . ASP C 1 17 ? -52.826 51.979 5.662 1.00 30.54 ? 17 ASP M O 1 ATOM 3463 C CB . ASP C 1 17 ? -51.329 54.117 3.716 1.00 39.62 ? 17 ASP M CB 1 ATOM 3464 C CG . ASP C 1 17 ? -51.143 55.491 3.111 1.00 49.36 ? 17 ASP M CG 1 ATOM 3465 O OD1 . ASP C 1 17 ? -51.664 56.473 3.649 1.00 52.88 ? 17 ASP M OD1 1 ATOM 3466 O OD2 . ASP C 1 17 ? -50.465 55.570 2.088 1.00 57.12 ? 17 ASP M OD2 1 ATOM 3467 N N . GLN C 1 18 ? -53.232 51.803 3.443 1.00 25.05 ? 18 GLN M N 1 ATOM 3468 C CA . GLN C 1 18 ? -53.356 50.375 3.523 1.00 27.22 ? 18 GLN M CA 1 ATOM 3469 C C . GLN C 1 18 ? -52.036 49.789 3.035 1.00 23.61 ? 18 GLN M C 1 ATOM 3470 O O . GLN C 1 18 ? -51.276 50.536 2.414 1.00 24.75 ? 18 GLN M O 1 ATOM 3471 C CB . GLN C 1 18 ? -54.569 49.969 2.688 1.00 33.26 ? 18 GLN M CB 1 ATOM 3472 C CG . GLN C 1 18 ? -54.506 49.922 1.174 1.00 41.52 ? 18 GLN M CG 1 ATOM 3473 C CD . GLN C 1 18 ? -54.615 48.485 0.687 1.00 47.45 ? 18 GLN M CD 1 ATOM 3474 O OE1 . GLN C 1 18 ? -53.768 47.967 -0.034 1.00 45.09 ? 18 GLN M OE1 1 ATOM 3475 N NE2 . GLN C 1 18 ? -55.685 47.799 1.083 1.00 52.34 ? 18 GLN M NE2 1 ATOM 3476 N N . ALA C 1 19 ? -51.681 48.525 3.268 1.00 17.78 ? 19 ALA M N 1 ATOM 3477 C CA . ALA C 1 19 ? -50.424 47.978 2.789 1.00 17.56 ? 19 ALA M CA 1 ATOM 3478 C C . ALA C 1 19 ? -50.711 46.622 2.214 1.00 22.57 ? 19 ALA M C 1 ATOM 3479 O O . ALA C 1 19 ? -51.542 45.905 2.787 1.00 20.96 ? 19 ALA M O 1 ATOM 3480 C CB . ALA C 1 19 ? -49.446 47.763 3.903 1.00 21.86 ? 19 ALA M CB 1 ATOM 3481 N N . SER C 1 20 ? -50.004 46.228 1.157 1.00 23.85 ? 20 SER M N 1 ATOM 3482 C CA . SER C 1 20 ? -50.278 44.938 0.533 1.00 24.98 ? 20 SER M CA 1 ATOM 3483 C C . SER C 1 20 ? -48.924 44.240 0.392 1.00 22.66 ? 20 SER M C 1 ATOM 3484 O O . SER C 1 20 ? -47.998 44.864 -0.142 1.00 29.33 ? 20 SER M O 1 ATOM 3485 C CB . SER C 1 20 ? -50.939 45.196 -0.834 1.00 30.76 ? 20 SER M CB 1 ATOM 3486 O OG . SER C 1 20 ? -51.511 46.495 -1.080 1.00 33.87 ? 20 SER M OG 1 ATOM 3487 N N . ILE C 1 21 ? -48.710 43.008 0.848 1.00 15.95 ? 21 ILE M N 1 ATOM 3488 C CA . ILE C 1 21 ? -47.389 42.372 0.856 1.00 20.97 ? 21 ILE M CA 1 ATOM 3489 C C . ILE C 1 21 ? -47.684 41.084 0.131 1.00 29.83 ? 21 ILE M C 1 ATOM 3490 O O . ILE C 1 21 ? -48.661 40.436 0.536 1.00 35.33 ? 21 ILE M O 1 ATOM 3491 C CB . ILE C 1 21 ? -46.874 42.038 2.313 1.00 16.45 ? 21 ILE M CB 1 ATOM 3492 C CG1 . ILE C 1 21 ? -46.618 43.294 3.139 1.00 15.51 ? 21 ILE M CG1 1 ATOM 3493 C CG2 . ILE C 1 21 ? -45.570 41.287 2.192 1.00 13.92 ? 21 ILE M CG2 1 ATOM 3494 C CD1 . ILE C 1 21 ? -46.579 43.163 4.658 1.00 14.95 ? 21 ILE M CD1 1 ATOM 3495 N N . SER C 1 22 ? -46.905 40.663 -0.869 1.00 30.32 ? 22 SER M N 1 ATOM 3496 C CA . SER C 1 22 ? -47.253 39.485 -1.634 1.00 27.43 ? 22 SER M CA 1 ATOM 3497 C C . SER C 1 22 ? -46.139 38.489 -1.513 1.00 24.93 ? 22 SER M C 1 ATOM 3498 O O . SER C 1 22 ? -44.966 38.866 -1.479 1.00 23.99 ? 22 SER M O 1 ATOM 3499 C CB . SER C 1 22 ? -47.499 39.896 -3.084 1.00 31.89 ? 22 SER M CB 1 ATOM 3500 O OG . SER C 1 22 ? -46.658 40.965 -3.525 1.00 36.08 ? 22 SER M OG 1 ATOM 3501 N N . CYS C 1 23 ? -46.517 37.227 -1.397 1.00 26.21 ? 23 CYS M N 1 ATOM 3502 C CA . CYS C 1 23 ? -45.598 36.146 -1.112 1.00 28.69 ? 23 CYS M CA 1 ATOM 3503 C C . CYS C 1 23 ? -45.897 35.025 -2.111 1.00 34.79 ? 23 CYS M C 1 ATOM 3504 O O . CYS C 1 23 ? -46.836 34.222 -1.956 1.00 37.48 ? 23 CYS M O 1 ATOM 3505 C CB . CYS C 1 23 ? -45.868 35.797 0.331 1.00 22.09 ? 23 CYS M CB 1 ATOM 3506 S SG . CYS C 1 23 ? -45.623 34.093 0.867 1.00 25.48 ? 23 CYS M SG 1 ATOM 3507 N N . ARG C 1 24 ? -45.176 35.024 -3.237 1.00 35.83 ? 24 ARG M N 1 ATOM 3508 C CA . ARG C 1 24 ? -45.460 34.034 -4.256 1.00 38.67 ? 24 ARG M CA 1 ATOM 3509 C C . ARG C 1 24 ? -44.507 32.909 -4.068 1.00 36.50 ? 24 ARG M C 1 ATOM 3510 O O . ARG C 1 24 ? -43.430 33.059 -3.525 1.00 31.76 ? 24 ARG M O 1 ATOM 3511 C CB . ARG C 1 24 ? -45.348 34.620 -5.694 1.00 44.11 ? 24 ARG M CB 1 ATOM 3512 C CG . ARG C 1 24 ? -44.721 36.009 -5.986 1.00 55.07 ? 24 ARG M CG 1 ATOM 3513 C CD . ARG C 1 24 ? -43.194 35.952 -6.169 1.00 61.37 ? 24 ARG M CD 1 ATOM 3514 N NE . ARG C 1 24 ? -42.656 37.111 -6.884 1.00 62.38 ? 24 ARG M NE 1 ATOM 3515 C CZ . ARG C 1 24 ? -41.463 37.105 -7.503 1.00 60.07 ? 24 ARG M CZ 1 ATOM 3516 N NH1 . ARG C 1 24 ? -40.658 36.042 -7.495 1.00 57.65 ? 24 ARG M NH1 1 ATOM 3517 N NH2 . ARG C 1 24 ? -41.069 38.192 -8.165 1.00 61.70 ? 24 ARG M NH2 1 ATOM 3518 N N . SER C 1 25 ? -44.940 31.748 -4.469 1.00 43.18 ? 25 SER M N 1 ATOM 3519 C CA . SER C 1 25 ? -44.158 30.546 -4.278 1.00 50.82 ? 25 SER M CA 1 ATOM 3520 C C . SER C 1 25 ? -43.568 29.992 -5.558 1.00 55.08 ? 25 SER M C 1 ATOM 3521 O O . SER C 1 25 ? -43.914 30.431 -6.679 1.00 61.68 ? 25 SER M O 1 ATOM 3522 C CB . SER C 1 25 ? -45.050 29.510 -3.674 1.00 47.77 ? 25 SER M CB 1 ATOM 3523 O OG . SER C 1 25 ? -44.179 28.505 -3.164 1.00 46.67 ? 25 SER M OG 1 ATOM 3524 N N . ASN C 1 26 ? -42.643 29.067 -5.473 1.00 52.76 ? 26 ASN M N 1 ATOM 3525 C CA . ASN C 1 26 ? -42.221 28.461 -6.728 1.00 55.32 ? 26 ASN M CA 1 ATOM 3526 C C . ASN C 1 26 ? -42.883 27.091 -6.763 1.00 54.70 ? 26 ASN M C 1 ATOM 3527 O O . ASN C 1 26 ? -42.545 26.277 -7.624 1.00 61.51 ? 26 ASN M O 1 ATOM 3528 C CB . ASN C 1 26 ? -40.695 28.344 -6.849 1.00 59.78 ? 26 ASN M CB 1 ATOM 3529 C CG . ASN C 1 26 ? -39.912 27.302 -6.079 1.00 66.85 ? 26 ASN M CG 1 ATOM 3530 O OD1 . ASN C 1 26 ? -40.381 26.755 -5.094 1.00 70.55 ? 26 ASN M OD1 1 ATOM 3531 N ND2 . ASN C 1 26 ? -38.669 27.077 -6.500 1.00 74.38 ? 26 ASN M ND2 1 ATOM 3532 N N . GLN C 1 27 ? -43.766 26.766 -5.837 1.00 50.82 ? 27 GLN M N 1 ATOM 3533 C CA . GLN C 1 27 ? -44.426 25.512 -5.923 1.00 52.98 ? 27 GLN M CA 1 ATOM 3534 C C . GLN C 1 27 ? -45.784 25.632 -5.300 1.00 54.97 ? 27 GLN M C 1 ATOM 3535 O O . GLN C 1 27 ? -46.039 26.479 -4.445 1.00 57.02 ? 27 GLN M O 1 ATOM 3536 C CB . GLN C 1 27 ? -43.670 24.410 -5.213 1.00 44.31 ? 27 GLN M CB 1 ATOM 3537 C CG . GLN C 1 27 ? -44.154 23.110 -5.683 1.00 43.13 ? 27 GLN M CG 1 ATOM 3538 C CD . GLN C 1 27 ? -43.370 21.974 -5.097 1.00 48.58 ? 27 GLN M CD 1 ATOM 3539 O OE1 . GLN C 1 27 ? -43.923 21.196 -4.320 1.00 46.56 ? 27 GLN M OE1 1 ATOM 3540 N NE2 . GLN C 1 27 ? -42.082 21.822 -5.443 1.00 49.86 ? 27 GLN M NE2 1 ATOM 3541 N N . THR C 1 28 A -46.668 24.789 -5.821 1.00 59.87 ? 27 THR M N 1 ATOM 3542 C CA . THR C 1 28 A -48.040 24.734 -5.408 1.00 65.17 ? 27 THR M CA 1 ATOM 3543 C C . THR C 1 28 A -48.151 24.294 -3.965 1.00 66.48 ? 27 THR M C 1 ATOM 3544 O O . THR C 1 28 A -47.692 23.231 -3.499 1.00 62.27 ? 27 THR M O 1 ATOM 3545 C CB . THR C 1 28 A -48.837 23.797 -6.334 1.00 68.17 ? 27 THR M CB 1 ATOM 3546 O OG1 . THR C 1 28 A -48.054 23.496 -7.507 1.00 72.19 ? 27 THR M OG1 1 ATOM 3547 C CG2 . THR C 1 28 A -50.159 24.470 -6.684 1.00 62.04 ? 27 THR M CG2 1 ATOM 3548 N N . ILE C 1 29 B -48.652 25.351 -3.313 1.00 65.96 ? 27 ILE M N 1 ATOM 3549 C CA . ILE C 1 29 B -48.994 25.322 -1.906 1.00 63.24 ? 27 ILE M CA 1 ATOM 3550 C C . ILE C 1 29 B -50.457 24.960 -1.844 1.00 61.29 ? 27 ILE M C 1 ATOM 3551 O O . ILE C 1 29 B -50.939 24.595 -0.772 1.00 62.77 ? 27 ILE M O 1 ATOM 3552 C CB . ILE C 1 29 B -48.800 26.683 -1.220 1.00 60.42 ? 27 ILE M CB 1 ATOM 3553 C CG1 . ILE C 1 29 B -47.698 27.513 -1.867 1.00 60.58 ? 27 ILE M CG1 1 ATOM 3554 C CG2 . ILE C 1 29 B -48.482 26.369 0.233 1.00 59.85 ? 27 ILE M CG2 1 ATOM 3555 C CD1 . ILE C 1 29 B -47.145 28.669 -1.046 1.00 63.65 ? 27 ILE M CD1 1 ATOM 3556 N N . LEU C 1 30 C -51.206 25.125 -2.947 1.00 59.81 ? 27 LEU M N 1 ATOM 3557 C CA . LEU C 1 30 C -52.582 24.683 -3.023 1.00 60.44 ? 27 LEU M CA 1 ATOM 3558 C C . LEU C 1 30 C -52.526 23.203 -2.772 1.00 56.16 ? 27 LEU M C 1 ATOM 3559 O O . LEU C 1 30 C -51.727 22.462 -3.349 1.00 53.22 ? 27 LEU M O 1 ATOM 3560 C CB . LEU C 1 30 C -53.202 24.934 -4.403 1.00 67.32 ? 27 LEU M CB 1 ATOM 3561 C CG . LEU C 1 30 C -53.918 23.895 -5.300 1.00 76.24 ? 27 LEU M CG 1 ATOM 3562 C CD1 . LEU C 1 30 C -55.273 23.448 -4.722 1.00 75.65 ? 27 LEU M CD1 1 ATOM 3563 C CD2 . LEU C 1 30 C -54.084 24.539 -6.684 1.00 76.65 ? 27 LEU M CD2 1 ATOM 3564 N N . LEU C 1 31 D -53.364 22.856 -1.826 1.00 51.50 ? 27 LEU M N 1 ATOM 3565 C CA . LEU C 1 31 D -53.516 21.482 -1.524 1.00 49.68 ? 27 LEU M CA 1 ATOM 3566 C C . LEU C 1 31 D -54.990 21.272 -1.733 1.00 55.56 ? 27 LEU M C 1 ATOM 3567 O O . LEU C 1 31 D -55.850 22.080 -1.348 1.00 55.31 ? 27 LEU M O 1 ATOM 3568 C CB . LEU C 1 31 D -53.094 21.210 -0.095 1.00 41.84 ? 27 LEU M CB 1 ATOM 3569 C CG . LEU C 1 31 D -51.958 20.197 -0.015 1.00 37.50 ? 27 LEU M CG 1 ATOM 3570 C CD1 . LEU C 1 31 D -50.791 20.725 -0.822 1.00 36.15 ? 27 LEU M CD1 1 ATOM 3571 C CD2 . LEU C 1 31 D -51.512 19.975 1.427 1.00 35.43 ? 27 LEU M CD2 1 ATOM 3572 N N . SER C 1 32 E -55.168 20.166 -2.443 1.00 59.45 ? 27 SER M N 1 ATOM 3573 C CA . SER C 1 32 E -56.442 19.579 -2.797 1.00 60.95 ? 27 SER M CA 1 ATOM 3574 C C . SER C 1 32 E -57.395 19.488 -1.618 1.00 61.77 ? 27 SER M C 1 ATOM 3575 O O . SER C 1 32 E -58.512 19.993 -1.667 1.00 63.41 ? 27 SER M O 1 ATOM 3576 C CB . SER C 1 32 E -56.145 18.202 -3.364 1.00 63.68 ? 27 SER M CB 1 ATOM 3577 O OG . SER C 1 32 E -55.285 17.487 -2.463 1.00 67.95 ? 27 SER M OG 1 ATOM 3578 N N . ASP C 1 33 ? -56.856 18.898 -0.542 1.00 62.45 ? 28 ASP M N 1 ATOM 3579 C CA . ASP C 1 33 ? -57.594 18.594 0.673 1.00 69.22 ? 28 ASP M CA 1 ATOM 3580 C C . ASP C 1 33 ? -58.267 19.815 1.302 1.00 73.79 ? 28 ASP M C 1 ATOM 3581 O O . ASP C 1 33 ? -59.491 19.989 1.381 1.00 68.83 ? 28 ASP M O 1 ATOM 3582 C CB . ASP C 1 33 ? -56.677 17.984 1.762 1.00 68.68 ? 28 ASP M CB 1 ATOM 3583 C CG . ASP C 1 33 ? -55.856 16.722 1.526 1.00 71.61 ? 28 ASP M CG 1 ATOM 3584 O OD1 . ASP C 1 33 ? -55.393 16.461 0.407 1.00 73.55 ? 28 ASP M OD1 1 ATOM 3585 O OD2 . ASP C 1 33 ? -55.654 16.010 2.515 1.00 71.19 ? 28 ASP M OD2 1 ATOM 3586 N N . GLY C 1 34 ? -57.352 20.655 1.772 1.00 81.34 ? 29 GLY M N 1 ATOM 3587 C CA . GLY C 1 34 ? -57.660 21.846 2.527 1.00 87.76 ? 29 GLY M CA 1 ATOM 3588 C C . GLY C 1 34 ? -56.697 22.848 1.955 1.00 88.82 ? 29 GLY M C 1 ATOM 3589 O O . GLY C 1 34 ? -55.465 22.686 2.036 1.00 89.07 ? 29 GLY M O 1 ATOM 3590 N N . ASP C 1 35 ? -57.355 23.778 1.262 1.00 85.94 ? 30 ASP M N 1 ATOM 3591 C CA . ASP C 1 35 ? -56.673 24.813 0.531 1.00 83.60 ? 30 ASP M CA 1 ATOM 3592 C C . ASP C 1 35 ? -55.644 25.606 1.349 1.00 79.83 ? 30 ASP M C 1 ATOM 3593 O O . ASP C 1 35 ? -55.962 26.590 2.018 1.00 85.07 ? 30 ASP M O 1 ATOM 3594 C CB . ASP C 1 35 ? -57.759 25.732 -0.073 1.00 83.96 ? 30 ASP M CB 1 ATOM 3595 C CG . ASP C 1 35 ? -57.527 26.185 -1.521 1.00 86.22 ? 30 ASP M CG 1 ATOM 3596 O OD1 . ASP C 1 35 ? -56.954 25.443 -2.328 1.00 85.55 ? 30 ASP M OD1 1 ATOM 3597 O OD2 . ASP C 1 35 ? -57.948 27.294 -1.848 1.00 86.48 ? 30 ASP M OD2 1 ATOM 3598 N N . THR C 1 36 ? -54.431 25.037 1.362 1.00 67.55 ? 31 THR M N 1 ATOM 3599 C CA . THR C 1 36 ? -53.223 25.694 1.803 1.00 61.13 ? 31 THR M CA 1 ATOM 3600 C C . THR C 1 36 ? -52.872 26.142 3.240 1.00 54.08 ? 31 THR M C 1 ATOM 3601 O O . THR C 1 36 ? -53.413 27.055 3.875 1.00 45.12 ? 31 THR M O 1 ATOM 3602 C CB . THR C 1 36 ? -53.089 26.869 0.795 1.00 64.27 ? 31 THR M CB 1 ATOM 3603 O OG1 . THR C 1 36 ? -53.234 26.339 -0.516 1.00 69.08 ? 31 THR M OG1 1 ATOM 3604 C CG2 . THR C 1 36 ? -51.737 27.511 0.825 1.00 70.67 ? 31 THR M CG2 1 ATOM 3605 N N . TYR C 1 37 ? -51.771 25.505 3.686 1.00 46.50 ? 32 TYR M N 1 ATOM 3606 C CA . TYR C 1 37 ? -51.081 25.803 4.941 1.00 33.69 ? 32 TYR M CA 1 ATOM 3607 C C . TYR C 1 37 ? -50.040 26.914 4.809 1.00 28.46 ? 32 TYR M C 1 ATOM 3608 O O . TYR C 1 37 ? -48.826 26.716 4.954 1.00 22.17 ? 32 TYR M O 1 ATOM 3609 C CB . TYR C 1 37 ? -50.361 24.611 5.447 1.00 34.57 ? 32 TYR M CB 1 ATOM 3610 C CG . TYR C 1 37 ? -51.193 23.628 6.218 1.00 42.18 ? 32 TYR M CG 1 ATOM 3611 C CD1 . TYR C 1 37 ? -52.222 24.039 7.041 1.00 40.93 ? 32 TYR M CD1 1 ATOM 3612 C CD2 . TYR C 1 37 ? -50.843 22.306 6.098 1.00 46.84 ? 32 TYR M CD2 1 ATOM 3613 C CE1 . TYR C 1 37 ? -52.924 23.109 7.757 1.00 38.85 ? 32 TYR M CE1 1 ATOM 3614 C CE2 . TYR C 1 37 ? -51.544 21.375 6.802 1.00 47.38 ? 32 TYR M CE2 1 ATOM 3615 C CZ . TYR C 1 37 ? -52.563 21.793 7.625 1.00 46.77 ? 32 TYR M CZ 1 ATOM 3616 O OH . TYR C 1 37 ? -53.242 20.825 8.321 1.00 53.43 ? 32 TYR M OH 1 ATOM 3617 N N . LEU C 1 38 ? -50.573 28.075 4.456 1.00 25.45 ? 33 LEU M N 1 ATOM 3618 C CA . LEU C 1 38 ? -49.837 29.307 4.308 1.00 19.92 ? 33 LEU M CA 1 ATOM 3619 C C . LEU C 1 38 ? -50.224 30.095 5.566 1.00 24.69 ? 33 LEU M C 1 ATOM 3620 O O . LEU C 1 38 ? -51.370 30.046 6.037 1.00 12.68 ? 33 LEU M O 1 ATOM 3621 C CB . LEU C 1 38 ? -50.318 29.948 3.056 1.00 11.43 ? 33 LEU M CB 1 ATOM 3622 C CG . LEU C 1 38 ? -49.757 31.184 2.432 1.00 14.91 ? 33 LEU M CG 1 ATOM 3623 C CD1 . LEU C 1 38 ? -50.070 32.389 3.310 1.00 26.87 ? 33 LEU M CD1 1 ATOM 3624 C CD2 . LEU C 1 38 ? -48.295 31.006 2.215 1.00 16.24 ? 33 LEU M CD2 1 ATOM 3625 N N . GLU C 1 39 ? -49.240 30.736 6.201 1.00 32.26 ? 34 GLU M N 1 ATOM 3626 C CA . GLU C 1 39 ? -49.427 31.561 7.392 1.00 29.54 ? 34 GLU M CA 1 ATOM 3627 C C . GLU C 1 39 ? -48.583 32.847 7.307 1.00 28.22 ? 34 GLU M C 1 ATOM 3628 O O . GLU C 1 39 ? -47.573 32.934 6.575 1.00 23.57 ? 34 GLU M O 1 ATOM 3629 C CB . GLU C 1 39 ? -49.019 30.816 8.651 1.00 25.26 ? 34 GLU M CB 1 ATOM 3630 C CG . GLU C 1 39 ? -49.869 29.635 9.038 1.00 29.13 ? 34 GLU M CG 1 ATOM 3631 C CD . GLU C 1 39 ? -49.808 28.386 8.153 1.00 30.60 ? 34 GLU M CD 1 ATOM 3632 O OE1 . GLU C 1 39 ? -48.750 28.104 7.608 1.00 30.18 ? 34 GLU M OE1 1 ATOM 3633 O OE2 . GLU C 1 39 ? -50.814 27.687 8.002 1.00 32.76 ? 34 GLU M OE2 1 ATOM 3634 N N . TRP C 1 40 ? -49.023 33.865 8.036 1.00 19.25 ? 35 TRP M N 1 ATOM 3635 C CA . TRP C 1 40 ? -48.327 35.114 8.057 1.00 19.10 ? 35 TRP M CA 1 ATOM 3636 C C . TRP C 1 40 ? -48.043 35.414 9.503 1.00 17.83 ? 35 TRP M C 1 ATOM 3637 O O . TRP C 1 40 ? -48.958 35.339 10.338 1.00 6.00 ? 35 TRP M O 1 ATOM 3638 C CB . TRP C 1 40 ? -49.176 36.215 7.507 1.00 26.70 ? 35 TRP M CB 1 ATOM 3639 C CG . TRP C 1 40 ? -49.358 36.233 6.001 1.00 31.32 ? 35 TRP M CG 1 ATOM 3640 C CD1 . TRP C 1 40 ? -50.337 35.508 5.384 1.00 30.92 ? 35 TRP M CD1 1 ATOM 3641 C CD2 . TRP C 1 40 ? -48.625 37.003 5.140 1.00 32.48 ? 35 TRP M CD2 1 ATOM 3642 N NE1 . TRP C 1 40 ? -50.233 35.831 4.126 1.00 32.60 ? 35 TRP M NE1 1 ATOM 3643 C CE2 . TRP C 1 40 ? -49.233 36.716 3.936 1.00 33.78 ? 35 TRP M CE2 1 ATOM 3644 C CE3 . TRP C 1 40 ? -47.566 37.881 5.224 1.00 31.64 ? 35 TRP M CE3 1 ATOM 3645 C CZ2 . TRP C 1 40 ? -48.774 37.318 2.778 1.00 35.25 ? 35 TRP M CZ2 1 ATOM 3646 C CZ3 . TRP C 1 40 ? -47.118 38.474 4.069 1.00 33.72 ? 35 TRP M CZ3 1 ATOM 3647 C CH2 . TRP C 1 40 ? -47.713 38.197 2.853 1.00 33.64 ? 35 TRP M CH2 1 ATOM 3648 N N . TYR C 1 41 ? -46.752 35.729 9.671 1.00 16.26 ? 36 TYR M N 1 ATOM 3649 C CA . TYR C 1 41 ? -46.074 36.086 10.899 1.00 14.38 ? 36 TYR M CA 1 ATOM 3650 C C . TYR C 1 41 ? -45.649 37.566 11.031 1.00 14.27 ? 36 TYR M C 1 ATOM 3651 O O . TYR C 1 41 ? -45.333 38.242 10.046 1.00 11.95 ? 36 TYR M O 1 ATOM 3652 C CB . TYR C 1 41 ? -44.849 35.196 11.010 1.00 18.26 ? 36 TYR M CB 1 ATOM 3653 C CG . TYR C 1 41 ? -45.186 33.752 11.317 1.00 24.58 ? 36 TYR M CG 1 ATOM 3654 C CD1 . TYR C 1 41 ? -45.493 33.321 12.600 1.00 26.23 ? 36 TYR M CD1 1 ATOM 3655 C CD2 . TYR C 1 41 ? -45.212 32.860 10.276 1.00 29.05 ? 36 TYR M CD2 1 ATOM 3656 C CE1 . TYR C 1 41 ? -45.841 31.998 12.818 1.00 27.62 ? 36 TYR M CE1 1 ATOM 3657 C CE2 . TYR C 1 41 ? -45.553 31.536 10.495 1.00 30.42 ? 36 TYR M CE2 1 ATOM 3658 C CZ . TYR C 1 41 ? -45.865 31.107 11.756 1.00 26.68 ? 36 TYR M CZ 1 ATOM 3659 O OH . TYR C 1 41 ? -46.201 29.782 11.928 1.00 23.04 ? 36 TYR M OH 1 ATOM 3660 N N . LEU C 1 42 ? -45.605 38.111 12.250 1.00 14.58 ? 37 LEU M N 1 ATOM 3661 C CA . LEU C 1 42 ? -45.143 39.471 12.498 1.00 13.14 ? 37 LEU M CA 1 ATOM 3662 C C . LEU C 1 42 ? -44.035 39.410 13.537 1.00 14.80 ? 37 LEU M C 1 ATOM 3663 O O . LEU C 1 42 ? -44.183 38.722 14.566 1.00 11.24 ? 37 LEU M O 1 ATOM 3664 C CB . LEU C 1 42 ? -46.256 40.365 13.050 1.00 8.11 ? 37 LEU M CB 1 ATOM 3665 C CG . LEU C 1 42 ? -45.902 41.752 13.601 1.00 2.00 ? 37 LEU M CG 1 ATOM 3666 C CD1 . LEU C 1 42 ? -44.962 42.510 12.694 1.00 2.00 ? 37 LEU M CD1 1 ATOM 3667 C CD2 . LEU C 1 42 ? -47.176 42.488 13.785 1.00 2.00 ? 37 LEU M CD2 1 ATOM 3668 N N . GLN C 1 43 ? -42.937 40.137 13.257 1.00 12.23 ? 38 GLN M N 1 ATOM 3669 C CA . GLN C 1 43 ? -41.833 40.233 14.195 1.00 11.63 ? 38 GLN M CA 1 ATOM 3670 C C . GLN C 1 43 ? -41.516 41.688 14.506 1.00 18.25 ? 38 GLN M C 1 ATOM 3671 O O . GLN C 1 43 ? -40.757 42.396 13.794 1.00 15.75 ? 38 GLN M O 1 ATOM 3672 C CB . GLN C 1 43 ? -40.562 39.580 13.668 1.00 4.85 ? 38 GLN M CB 1 ATOM 3673 C CG . GLN C 1 43 ? -39.729 39.184 14.880 1.00 2.02 ? 38 GLN M CG 1 ATOM 3674 C CD . GLN C 1 43 ? -38.364 38.627 14.580 1.00 4.48 ? 38 GLN M CD 1 ATOM 3675 O OE1 . GLN C 1 43 ? -37.862 38.707 13.467 1.00 5.04 ? 38 GLN M OE1 1 ATOM 3676 N NE2 . GLN C 1 43 ? -37.674 38.068 15.547 1.00 8.98 ? 38 GLN M NE2 1 ATOM 3677 N N . LYS C 1 44 ? -42.201 42.106 15.594 1.00 20.00 ? 39 LYS M N 1 ATOM 3678 C CA . LYS C 1 44 ? -41.988 43.454 16.099 1.00 27.37 ? 39 LYS M CA 1 ATOM 3679 C C . LYS C 1 44 ? -40.543 43.652 16.588 1.00 31.22 ? 39 LYS M C 1 ATOM 3680 O O . LYS C 1 44 ? -39.931 42.684 17.076 1.00 32.26 ? 39 LYS M O 1 ATOM 3681 C CB . LYS C 1 44 ? -42.988 43.721 17.217 1.00 24.54 ? 39 LYS M CB 1 ATOM 3682 C CG . LYS C 1 44 ? -44.231 44.302 16.579 1.00 22.59 ? 39 LYS M CG 1 ATOM 3683 C CD . LYS C 1 44 ? -45.302 44.496 17.616 1.00 25.27 ? 39 LYS M CD 1 ATOM 3684 C CE . LYS C 1 44 ? -46.615 44.548 16.865 1.00 30.07 ? 39 LYS M CE 1 ATOM 3685 N NZ . LYS C 1 44 ? -47.770 44.514 17.747 1.00 33.05 ? 39 LYS M NZ 1 ATOM 3686 N N . PRO C 1 45 ? -39.920 44.840 16.477 1.00 31.84 ? 40 PRO M N 1 ATOM 3687 C CA . PRO C 1 45 ? -38.501 45.034 16.771 1.00 29.23 ? 40 PRO M CA 1 ATOM 3688 C C . PRO C 1 45 ? -38.270 44.585 18.197 1.00 26.49 ? 40 PRO M C 1 ATOM 3689 O O . PRO C 1 45 ? -38.990 44.971 19.122 1.00 21.27 ? 40 PRO M O 1 ATOM 3690 C CB . PRO C 1 45 ? -38.240 46.513 16.585 1.00 30.25 ? 40 PRO M CB 1 ATOM 3691 C CG . PRO C 1 45 ? -39.475 47.070 15.923 1.00 32.03 ? 40 PRO M CG 1 ATOM 3692 C CD . PRO C 1 45 ? -40.592 46.145 16.417 1.00 32.08 ? 40 PRO M CD 1 ATOM 3693 N N . GLY C 1 46 ? -37.365 43.631 18.312 1.00 36.29 ? 41 GLY M N 1 ATOM 3694 C CA . GLY C 1 46 ? -37.025 43.119 19.632 1.00 46.86 ? 41 GLY M CA 1 ATOM 3695 C C . GLY C 1 46 ? -38.038 42.134 20.230 1.00 48.41 ? 41 GLY M C 1 ATOM 3696 O O . GLY C 1 46 ? -38.118 41.962 21.457 1.00 50.11 ? 41 GLY M O 1 ATOM 3697 N N . GLN C 1 47 ? -38.846 41.460 19.417 1.00 43.78 ? 42 GLN M N 1 ATOM 3698 C CA . GLN C 1 47 ? -39.724 40.449 19.967 1.00 39.13 ? 42 GLN M CA 1 ATOM 3699 C C . GLN C 1 47 ? -39.578 39.177 19.145 1.00 33.07 ? 42 GLN M C 1 ATOM 3700 O O . GLN C 1 47 ? -38.871 39.187 18.132 1.00 37.41 ? 42 GLN M O 1 ATOM 3701 C CB . GLN C 1 47 ? -41.152 40.956 19.930 1.00 42.26 ? 42 GLN M CB 1 ATOM 3702 C CG . GLN C 1 47 ? -41.460 42.081 20.889 1.00 40.80 ? 42 GLN M CG 1 ATOM 3703 C CD . GLN C 1 47 ? -42.943 42.356 20.945 1.00 45.31 ? 42 GLN M CD 1 ATOM 3704 O OE1 . GLN C 1 47 ? -43.779 41.466 21.070 1.00 50.36 ? 42 GLN M OE1 1 ATOM 3705 N NE2 . GLN C 1 47 ? -43.349 43.610 20.882 1.00 49.40 ? 42 GLN M NE2 1 ATOM 3706 N N . SER C 1 48 ? -40.155 38.057 19.568 1.00 28.99 ? 43 SER M N 1 ATOM 3707 C CA . SER C 1 48 ? -40.186 36.811 18.805 1.00 29.59 ? 43 SER M CA 1 ATOM 3708 C C . SER C 1 48 ? -41.317 36.928 17.776 1.00 24.53 ? 43 SER M C 1 ATOM 3709 O O . SER C 1 48 ? -42.169 37.800 17.965 1.00 23.00 ? 43 SER M O 1 ATOM 3710 C CB . SER C 1 48 ? -40.405 35.654 19.809 1.00 33.46 ? 43 SER M CB 1 ATOM 3711 O OG . SER C 1 48 ? -41.199 36.032 20.945 1.00 39.89 ? 43 SER M OG 1 ATOM 3712 N N . PRO C 1 49 ? -41.397 36.201 16.662 1.00 18.87 ? 44 PRO M N 1 ATOM 3713 C CA . PRO C 1 49 ? -42.543 36.236 15.783 1.00 16.60 ? 44 PRO M CA 1 ATOM 3714 C C . PRO C 1 49 ? -43.841 35.831 16.493 1.00 17.44 ? 44 PRO M C 1 ATOM 3715 O O . PRO C 1 49 ? -43.823 35.058 17.462 1.00 18.05 ? 44 PRO M O 1 ATOM 3716 C CB . PRO C 1 49 ? -42.123 35.315 14.666 1.00 20.36 ? 44 PRO M CB 1 ATOM 3717 C CG . PRO C 1 49 ? -40.634 35.473 14.588 1.00 18.94 ? 44 PRO M CG 1 ATOM 3718 C CD . PRO C 1 49 ? -40.316 35.429 16.077 1.00 21.57 ? 44 PRO M CD 1 ATOM 3719 N N . LYS C 1 50 ? -44.958 36.412 16.051 1.00 15.81 ? 45 LYS M N 1 ATOM 3720 C CA . LYS C 1 50 ? -46.291 36.105 16.523 1.00 22.07 ? 45 LYS M CA 1 ATOM 3721 C C . LYS C 1 50 ? -47.095 35.599 15.326 1.00 29.60 ? 45 LYS M C 1 ATOM 3722 O O . LYS C 1 50 ? -46.743 35.976 14.194 1.00 36.07 ? 45 LYS M O 1 ATOM 3723 C CB . LYS C 1 50 ? -46.924 37.365 17.106 1.00 29.39 ? 45 LYS M CB 1 ATOM 3724 C CG . LYS C 1 50 ? -46.442 37.464 18.545 1.00 41.09 ? 45 LYS M CG 1 ATOM 3725 C CD . LYS C 1 50 ? -47.246 38.370 19.477 1.00 47.35 ? 45 LYS M CD 1 ATOM 3726 C CE . LYS C 1 50 ? -46.803 38.147 20.952 1.00 52.05 ? 45 LYS M CE 1 ATOM 3727 N NZ . LYS C 1 50 ? -47.234 36.876 21.532 1.00 48.64 ? 45 LYS M NZ 1 ATOM 3728 N N . LEU C 1 51 ? -48.143 34.760 15.436 1.00 28.36 ? 46 LEU M N 1 ATOM 3729 C CA . LEU C 1 51 ? -48.875 34.308 14.247 1.00 25.54 ? 46 LEU M CA 1 ATOM 3730 C C . LEU C 1 51 ? -49.979 35.282 13.922 1.00 21.12 ? 46 LEU M C 1 ATOM 3731 O O . LEU C 1 51 ? -50.681 35.658 14.842 1.00 21.12 ? 46 LEU M O 1 ATOM 3732 C CB . LEU C 1 51 ? -49.451 32.945 14.533 1.00 31.26 ? 46 LEU M CB 1 ATOM 3733 C CG . LEU C 1 51 ? -50.583 32.390 13.698 1.00 30.03 ? 46 LEU M CG 1 ATOM 3734 C CD1 . LEU C 1 51 ? -50.242 32.337 12.227 1.00 31.66 ? 46 LEU M CD1 1 ATOM 3735 C CD2 . LEU C 1 51 ? -50.868 31.021 14.248 1.00 26.72 ? 46 LEU M CD2 1 ATOM 3736 N N . LEU C 1 52 ? -50.213 35.723 12.701 1.00 24.27 ? 47 LEU M N 1 ATOM 3737 C CA . LEU C 1 52 ? -51.267 36.704 12.434 1.00 24.01 ? 47 LEU M CA 1 ATOM 3738 C C . LEU C 1 52 ? -52.408 36.061 11.695 1.00 26.68 ? 47 LEU M C 1 ATOM 3739 O O . LEU C 1 52 ? -53.564 36.258 12.062 1.00 25.53 ? 47 LEU M O 1 ATOM 3740 C CB . LEU C 1 52 ? -50.858 37.868 11.538 1.00 22.10 ? 47 LEU M CB 1 ATOM 3741 C CG . LEU C 1 52 ? -49.825 38.893 11.933 1.00 23.02 ? 47 LEU M CG 1 ATOM 3742 C CD1 . LEU C 1 52 ? -49.576 39.829 10.777 1.00 18.37 ? 47 LEU M CD1 1 ATOM 3743 C CD2 . LEU C 1 52 ? -50.313 39.668 13.142 1.00 27.60 ? 47 LEU M CD2 1 ATOM 3744 N N . ILE C 1 53 ? -52.101 35.312 10.642 1.00 24.68 ? 48 ILE M N 1 ATOM 3745 C CA . ILE C 1 53 ? -53.115 34.744 9.774 1.00 24.62 ? 48 ILE M CA 1 ATOM 3746 C C . ILE C 1 53 ? -52.657 33.353 9.435 1.00 29.51 ? 48 ILE M C 1 ATOM 3747 O O . ILE C 1 53 ? -51.482 33.213 9.080 1.00 34.56 ? 48 ILE M O 1 ATOM 3748 C CB . ILE C 1 53 ? -53.214 35.624 8.526 1.00 24.33 ? 48 ILE M CB 1 ATOM 3749 C CG1 . ILE C 1 53 ? -54.242 36.689 8.801 1.00 26.55 ? 48 ILE M CG1 1 ATOM 3750 C CG2 . ILE C 1 53 ? -53.579 34.830 7.300 1.00 21.02 ? 48 ILE M CG2 1 ATOM 3751 C CD1 . ILE C 1 53 ? -54.194 37.810 7.780 1.00 25.86 ? 48 ILE M CD1 1 ATOM 3752 N N . TYR C 1 54 ? -53.509 32.340 9.554 1.00 30.77 ? 49 TYR M N 1 ATOM 3753 C CA . TYR C 1 54 ? -53.138 30.980 9.200 1.00 30.80 ? 49 TYR M CA 1 ATOM 3754 C C . TYR C 1 54 ? -53.990 30.456 8.038 1.00 30.57 ? 49 TYR M C 1 ATOM 3755 O O . TYR C 1 54 ? -55.072 31.011 7.778 1.00 34.72 ? 49 TYR M O 1 ATOM 3756 C CB . TYR C 1 54 ? -53.263 30.064 10.476 1.00 36.54 ? 49 TYR M CB 1 ATOM 3757 C CG . TYR C 1 54 ? -54.619 29.839 11.169 1.00 41.86 ? 49 TYR M CG 1 ATOM 3758 C CD1 . TYR C 1 54 ? -55.668 29.323 10.445 1.00 43.91 ? 49 TYR M CD1 1 ATOM 3759 C CD2 . TYR C 1 54 ? -54.830 30.194 12.489 1.00 39.84 ? 49 TYR M CD2 1 ATOM 3760 C CE1 . TYR C 1 54 ? -56.898 29.174 11.000 1.00 41.83 ? 49 TYR M CE1 1 ATOM 3761 C CE2 . TYR C 1 54 ? -56.078 30.047 13.054 1.00 38.35 ? 49 TYR M CE2 1 ATOM 3762 C CZ . TYR C 1 54 ? -57.104 29.551 12.293 1.00 39.97 ? 49 TYR M CZ 1 ATOM 3763 O OH . TYR C 1 54 ? -58.405 29.524 12.747 1.00 46.09 ? 49 TYR M OH 1 ATOM 3764 N N . LYS C 1 55 ? -53.529 29.406 7.345 1.00 24.17 ? 50 LYS M N 1 ATOM 3765 C CA . LYS C 1 55 ? -54.257 28.745 6.272 1.00 23.69 ? 50 LYS M CA 1 ATOM 3766 C C . LYS C 1 55 ? -54.883 29.727 5.323 1.00 22.90 ? 50 LYS M C 1 ATOM 3767 O O . LYS C 1 55 ? -56.084 29.926 5.202 1.00 24.90 ? 50 LYS M O 1 ATOM 3768 C CB . LYS C 1 55 ? -55.311 27.840 6.879 1.00 31.54 ? 50 LYS M CB 1 ATOM 3769 C CG . LYS C 1 55 ? -54.832 26.422 7.214 1.00 34.15 ? 50 LYS M CG 1 ATOM 3770 C CD . LYS C 1 55 ? -55.591 25.821 8.410 1.00 36.76 ? 50 LYS M CD 1 ATOM 3771 C CE . LYS C 1 55 ? -57.129 25.857 8.398 1.00 36.25 ? 50 LYS M CE 1 ATOM 3772 N NZ . LYS C 1 55 ? -57.693 24.975 7.395 1.00 34.37 ? 50 LYS M NZ 1 ATOM 3773 N N . VAL C 1 56 ? -53.932 30.462 4.771 1.00 28.32 ? 51 VAL M N 1 ATOM 3774 C CA . VAL C 1 56 ? -54.091 31.579 3.848 1.00 27.94 ? 51 VAL M CA 1 ATOM 3775 C C . VAL C 1 56 ? -54.786 32.776 4.457 1.00 30.83 ? 51 VAL M C 1 ATOM 3776 O O . VAL C 1 56 ? -54.273 33.886 4.219 1.00 27.82 ? 51 VAL M O 1 ATOM 3777 C CB . VAL C 1 56 ? -54.879 31.238 2.564 1.00 22.93 ? 51 VAL M CB 1 ATOM 3778 C CG1 . VAL C 1 56 ? -54.668 32.360 1.556 1.00 24.61 ? 51 VAL M CG1 1 ATOM 3779 C CG2 . VAL C 1 56 ? -54.384 29.976 1.919 1.00 28.15 ? 51 VAL M CG2 1 ATOM 3780 N N . SER C 1 57 ? -55.945 32.579 5.123 1.00 31.81 ? 52 SER M N 1 ATOM 3781 C CA . SER C 1 57 ? -56.639 33.661 5.782 1.00 39.14 ? 52 SER M CA 1 ATOM 3782 C C . SER C 1 57 ? -57.586 33.336 6.924 1.00 37.50 ? 52 SER M C 1 ATOM 3783 O O . SER C 1 57 ? -58.799 33.330 6.771 1.00 45.91 ? 52 SER M O 1 ATOM 3784 C CB . SER C 1 57 ? -57.441 34.508 4.767 1.00 39.41 ? 52 SER M CB 1 ATOM 3785 O OG . SER C 1 57 ? -57.873 35.779 5.296 1.00 43.62 ? 52 SER M OG 1 ATOM 3786 N N . ASN C 1 58 ? -57.153 32.940 8.092 1.00 35.89 ? 53 ASN M N 1 ATOM 3787 C CA . ASN C 1 58 ? -58.033 33.048 9.236 1.00 39.79 ? 53 ASN M CA 1 ATOM 3788 C C . ASN C 1 58 ? -57.200 33.884 10.170 1.00 42.38 ? 53 ASN M C 1 ATOM 3789 O O . ASN C 1 58 ? -55.981 33.673 10.246 1.00 48.40 ? 53 ASN M O 1 ATOM 3790 C CB . ASN C 1 58 ? -58.276 31.788 9.946 1.00 44.33 ? 53 ASN M CB 1 ATOM 3791 C CG . ASN C 1 58 ? -59.283 30.846 9.357 1.00 49.39 ? 53 ASN M CG 1 ATOM 3792 O OD1 . ASN C 1 58 ? -59.898 30.079 10.099 1.00 56.48 ? 53 ASN M OD1 1 ATOM 3793 N ND2 . ASN C 1 58 ? -59.531 30.814 8.064 1.00 52.29 ? 53 ASN M ND2 1 ATOM 3794 N N . ARG C 1 59 ? -57.770 34.848 10.879 1.00 38.71 ? 54 ARG M N 1 ATOM 3795 C CA . ARG C 1 59 ? -56.935 35.661 11.737 1.00 34.45 ? 54 ARG M CA 1 ATOM 3796 C C . ARG C 1 59 ? -56.795 34.911 13.045 1.00 30.84 ? 54 ARG M C 1 ATOM 3797 O O . ARG C 1 59 ? -57.685 34.146 13.421 1.00 36.13 ? 54 ARG M O 1 ATOM 3798 C CB . ARG C 1 59 ? -57.586 37.037 11.865 1.00 34.63 ? 54 ARG M CB 1 ATOM 3799 C CG . ARG C 1 59 ? -57.318 37.793 10.545 1.00 36.82 ? 54 ARG M CG 1 ATOM 3800 C CD . ARG C 1 59 ? -57.839 39.216 10.539 1.00 42.00 ? 54 ARG M CD 1 ATOM 3801 N NE . ARG C 1 59 ? -59.284 39.280 10.387 1.00 46.13 ? 54 ARG M NE 1 ATOM 3802 C CZ . ARG C 1 59 ? -59.876 39.258 9.183 1.00 53.43 ? 54 ARG M CZ 1 ATOM 3803 N NH1 . ARG C 1 59 ? -59.181 39.183 8.032 1.00 57.65 ? 54 ARG M NH1 1 ATOM 3804 N NH2 . ARG C 1 59 ? -61.211 39.306 9.112 1.00 55.54 ? 54 ARG M NH2 1 ATOM 3805 N N . PHE C 1 60 ? -55.624 34.966 13.658 1.00 24.58 ? 55 PHE M N 1 ATOM 3806 C CA . PHE C 1 60 ? -55.420 34.266 14.891 1.00 22.71 ? 55 PHE M CA 1 ATOM 3807 C C . PHE C 1 60 ? -55.928 35.212 15.978 1.00 29.38 ? 55 PHE M C 1 ATOM 3808 O O . PHE C 1 60 ? -56.286 36.388 15.762 1.00 30.12 ? 55 PHE M O 1 ATOM 3809 C CB . PHE C 1 60 ? -53.922 33.944 15.009 1.00 22.78 ? 55 PHE M CB 1 ATOM 3810 C CG . PHE C 1 60 ? -53.521 33.120 16.234 1.00 22.75 ? 55 PHE M CG 1 ATOM 3811 C CD1 . PHE C 1 60 ? -53.809 31.781 16.305 1.00 24.73 ? 55 PHE M CD1 1 ATOM 3812 C CD2 . PHE C 1 60 ? -52.872 33.710 17.302 1.00 24.91 ? 55 PHE M CD2 1 ATOM 3813 C CE1 . PHE C 1 60 ? -53.452 31.061 17.431 1.00 29.43 ? 55 PHE M CE1 1 ATOM 3814 C CE2 . PHE C 1 60 ? -52.515 32.981 18.428 1.00 27.36 ? 55 PHE M CE2 1 ATOM 3815 C CZ . PHE C 1 60 ? -52.804 31.648 18.499 1.00 27.21 ? 55 PHE M CZ 1 ATOM 3816 N N . SER C 1 61 ? -56.013 34.649 17.181 1.00 30.61 ? 56 SER M N 1 ATOM 3817 C CA . SER C 1 61 ? -56.462 35.341 18.373 1.00 34.48 ? 56 SER M CA 1 ATOM 3818 C C . SER C 1 61 ? -55.916 36.760 18.541 1.00 33.97 ? 56 SER M C 1 ATOM 3819 O O . SER C 1 61 ? -54.712 36.995 18.467 1.00 38.35 ? 56 SER M O 1 ATOM 3820 C CB . SER C 1 61 ? -56.069 34.488 19.591 1.00 40.66 ? 56 SER M CB 1 ATOM 3821 O OG . SER C 1 61 ? -56.428 33.112 19.466 1.00 46.43 ? 56 SER M OG 1 ATOM 3822 N N . GLY C 1 62 ? -56.772 37.754 18.680 1.00 32.30 ? 57 GLY M N 1 ATOM 3823 C CA . GLY C 1 62 ? -56.267 39.076 18.992 1.00 31.51 ? 57 GLY M CA 1 ATOM 3824 C C . GLY C 1 62 ? -55.718 39.804 17.787 1.00 28.86 ? 57 GLY M C 1 ATOM 3825 O O . GLY C 1 62 ? -55.268 40.943 17.927 1.00 31.11 ? 57 GLY M O 1 ATOM 3826 N N . VAL C 1 63 ? -55.751 39.201 16.607 1.00 19.46 ? 58 VAL M N 1 ATOM 3827 C CA . VAL C 1 63 ? -55.320 39.924 15.445 1.00 14.76 ? 58 VAL M CA 1 ATOM 3828 C C . VAL C 1 63 ? -56.496 40.815 15.068 1.00 17.41 ? 58 VAL M C 1 ATOM 3829 O O . VAL C 1 63 ? -57.630 40.334 15.080 1.00 28.82 ? 58 VAL M O 1 ATOM 3830 C CB . VAL C 1 63 ? -55.006 38.921 14.389 1.00 14.85 ? 58 VAL M CB 1 ATOM 3831 C CG1 . VAL C 1 63 ? -54.652 39.571 13.067 1.00 19.71 ? 58 VAL M CG1 1 ATOM 3832 C CG2 . VAL C 1 63 ? -53.829 38.134 14.890 1.00 20.15 ? 58 VAL M CG2 1 ATOM 3833 N N . PRO C 1 64 ? -56.363 42.103 14.774 1.00 13.78 ? 59 PRO M N 1 ATOM 3834 C CA . PRO C 1 64 ? -57.460 42.923 14.314 1.00 10.41 ? 59 PRO M CA 1 ATOM 3835 C C . PRO C 1 64 ? -57.916 42.760 12.873 1.00 17.84 ? 59 PRO M C 1 ATOM 3836 O O . PRO C 1 64 ? -57.126 42.454 11.979 1.00 22.64 ? 59 PRO M O 1 ATOM 3837 C CB . PRO C 1 64 ? -56.970 44.308 14.662 1.00 11.16 ? 59 PRO M CB 1 ATOM 3838 C CG . PRO C 1 64 ? -55.479 44.282 14.589 1.00 6.02 ? 59 PRO M CG 1 ATOM 3839 C CD . PRO C 1 64 ? -55.214 42.915 15.165 1.00 15.19 ? 59 PRO M CD 1 ATOM 3840 N N . ASP C 1 65 ? -59.185 43.105 12.626 1.00 23.43 ? 60 ASP M N 1 ATOM 3841 C CA . ASP C 1 65 ? -59.823 43.071 11.312 1.00 27.25 ? 60 ASP M CA 1 ATOM 3842 C C . ASP C 1 65 ? -58.989 43.663 10.210 1.00 29.23 ? 60 ASP M C 1 ATOM 3843 O O . ASP C 1 65 ? -59.130 43.296 9.051 1.00 35.26 ? 60 ASP M O 1 ATOM 3844 C CB . ASP C 1 65 ? -61.112 43.860 11.262 1.00 36.88 ? 60 ASP M CB 1 ATOM 3845 C CG . ASP C 1 65 ? -62.256 43.338 12.109 1.00 44.98 ? 60 ASP M CG 1 ATOM 3846 O OD1 . ASP C 1 65 ? -61.998 42.688 13.120 1.00 48.19 ? 60 ASP M OD1 1 ATOM 3847 O OD2 . ASP C 1 65 ? -63.411 43.600 11.760 1.00 48.31 ? 60 ASP M OD2 1 ATOM 3848 N N . ARG C 1 66 ? -58.150 44.633 10.580 1.00 24.16 ? 61 ARG M N 1 ATOM 3849 C CA . ARG C 1 66 ? -57.272 45.317 9.637 1.00 21.03 ? 61 ARG M CA 1 ATOM 3850 C C . ARG C 1 66 ? -56.286 44.399 8.917 1.00 19.07 ? 61 ARG M C 1 ATOM 3851 O O . ARG C 1 66 ? -55.573 44.880 8.045 1.00 16.36 ? 61 ARG M O 1 ATOM 3852 C CB . ARG C 1 66 ? -56.477 46.411 10.364 1.00 15.52 ? 61 ARG M CB 1 ATOM 3853 C CG . ARG C 1 66 ? -57.362 47.519 10.877 1.00 15.88 ? 61 ARG M CG 1 ATOM 3854 C CD . ARG C 1 66 ? -56.834 48.090 12.172 1.00 22.51 ? 61 ARG M CD 1 ATOM 3855 N NE . ARG C 1 66 ? -55.556 48.775 12.052 1.00 26.32 ? 61 ARG M NE 1 ATOM 3856 C CZ . ARG C 1 66 ? -54.429 48.298 12.586 1.00 26.39 ? 61 ARG M CZ 1 ATOM 3857 N NH1 . ARG C 1 66 ? -54.352 47.168 13.254 1.00 30.39 ? 61 ARG M NH1 1 ATOM 3858 N NH2 . ARG C 1 66 ? -53.319 48.964 12.458 1.00 26.62 ? 61 ARG M NH2 1 ATOM 3859 N N . PHE C 1 67 ? -56.151 43.138 9.297 1.00 19.49 ? 62 PHE M N 1 ATOM 3860 C CA . PHE C 1 67 ? -55.252 42.226 8.647 1.00 21.01 ? 62 PHE M CA 1 ATOM 3861 C C . PHE C 1 67 ? -56.189 41.400 7.814 1.00 27.99 ? 62 PHE M C 1 ATOM 3862 O O . PHE C 1 67 ? -57.336 41.239 8.244 1.00 31.09 ? 62 PHE M O 1 ATOM 3863 C CB . PHE C 1 67 ? -54.542 41.412 9.722 1.00 18.99 ? 62 PHE M CB 1 ATOM 3864 C CG . PHE C 1 67 ? -53.520 42.346 10.378 1.00 22.02 ? 62 PHE M CG 1 ATOM 3865 C CD1 . PHE C 1 67 ? -52.270 42.517 9.813 1.00 21.95 ? 62 PHE M CD1 1 ATOM 3866 C CD2 . PHE C 1 67 ? -53.846 43.092 11.487 1.00 19.31 ? 62 PHE M CD2 1 ATOM 3867 C CE1 . PHE C 1 67 ? -51.366 43.416 10.340 1.00 18.01 ? 62 PHE M CE1 1 ATOM 3868 C CE2 . PHE C 1 67 ? -52.938 43.991 12.004 1.00 18.79 ? 62 PHE M CE2 1 ATOM 3869 C CZ . PHE C 1 67 ? -51.701 44.160 11.436 1.00 16.80 ? 62 PHE M CZ 1 ATOM 3870 N N . SER C 1 68 ? -55.819 40.953 6.605 1.00 31.47 ? 63 SER M N 1 ATOM 3871 C CA . SER C 1 68 ? -56.638 39.994 5.859 1.00 32.06 ? 63 SER M CA 1 ATOM 3872 C C . SER C 1 68 ? -55.778 39.271 4.842 1.00 34.23 ? 63 SER M C 1 ATOM 3873 O O . SER C 1 68 ? -54.973 39.890 4.141 1.00 38.01 ? 63 SER M O 1 ATOM 3874 C CB . SER C 1 68 ? -57.808 40.702 5.154 1.00 29.85 ? 63 SER M CB 1 ATOM 3875 O OG . SER C 1 68 ? -57.611 42.073 4.817 1.00 28.40 ? 63 SER M OG 1 ATOM 3876 N N . GLY C 1 69 ? -55.828 37.944 4.841 1.00 36.66 ? 64 GLY M N 1 ATOM 3877 C CA . GLY C 1 69 ? -55.002 37.186 3.933 1.00 34.75 ? 64 GLY M CA 1 ATOM 3878 C C . GLY C 1 69 ? -55.779 36.975 2.671 1.00 38.66 ? 64 GLY M C 1 ATOM 3879 O O . GLY C 1 69 ? -57.003 36.854 2.722 1.00 39.88 ? 64 GLY M O 1 ATOM 3880 N N . SER C 1 70 ? -55.120 36.994 1.529 1.00 46.39 ? 65 SER M N 1 ATOM 3881 C CA . SER C 1 70 ? -55.766 36.660 0.275 1.00 48.41 ? 65 SER M CA 1 ATOM 3882 C C . SER C 1 70 ? -54.845 35.747 -0.515 1.00 52.31 ? 65 SER M C 1 ATOM 3883 O O . SER C 1 70 ? -53.697 35.482 -0.128 1.00 55.52 ? 65 SER M O 1 ATOM 3884 C CB . SER C 1 70 ? -56.071 37.937 -0.545 1.00 48.38 ? 65 SER M CB 1 ATOM 3885 O OG . SER C 1 70 ? -55.019 38.875 -0.763 1.00 47.27 ? 65 SER M OG 1 ATOM 3886 N N . GLY C 1 71 ? -55.351 35.303 -1.659 1.00 55.68 ? 66 GLY M N 1 ATOM 3887 C CA . GLY C 1 71 ? -54.596 34.477 -2.577 1.00 49.85 ? 66 GLY M CA 1 ATOM 3888 C C . GLY C 1 71 ? -55.071 33.051 -2.466 1.00 46.62 ? 66 GLY M C 1 ATOM 3889 O O . GLY C 1 71 ? -55.988 32.730 -1.704 1.00 41.12 ? 66 GLY M O 1 ATOM 3890 N N . SER C 1 72 ? -54.465 32.238 -3.315 1.00 49.65 ? 67 SER M N 1 ATOM 3891 C CA . SER C 1 72 ? -54.710 30.812 -3.344 1.00 46.81 ? 67 SER M CA 1 ATOM 3892 C C . SER C 1 72 ? -53.714 30.202 -4.307 1.00 42.44 ? 67 SER M C 1 ATOM 3893 O O . SER C 1 72 ? -53.159 30.867 -5.203 1.00 45.08 ? 67 SER M O 1 ATOM 3894 C CB . SER C 1 72 ? -56.105 30.470 -3.845 1.00 48.28 ? 67 SER M CB 1 ATOM 3895 O OG . SER C 1 72 ? -56.401 29.122 -3.510 1.00 49.94 ? 67 SER M OG 1 ATOM 3896 N N . GLY C 1 73 ? -53.424 28.935 -4.027 1.00 35.90 ? 68 GLY M N 1 ATOM 3897 C CA . GLY C 1 73 ? -52.632 28.133 -4.922 1.00 32.78 ? 68 GLY M CA 1 ATOM 3898 C C . GLY C 1 73 ? -51.134 28.337 -4.842 1.00 34.04 ? 68 GLY M C 1 ATOM 3899 O O . GLY C 1 73 ? -50.415 27.471 -4.323 1.00 30.24 ? 68 GLY M O 1 ATOM 3900 N N . THR C 1 74 ? -50.679 29.449 -5.421 1.00 38.59 ? 69 THR M N 1 ATOM 3901 C CA . THR C 1 74 ? -49.273 29.794 -5.420 1.00 40.66 ? 69 THR M CA 1 ATOM 3902 C C . THR C 1 74 ? -48.991 31.254 -5.039 1.00 46.23 ? 69 THR M C 1 ATOM 3903 O O . THR C 1 74 ? -47.877 31.592 -4.620 1.00 46.83 ? 69 THR M O 1 ATOM 3904 C CB . THR C 1 74 ? -48.789 29.421 -6.810 1.00 38.59 ? 69 THR M CB 1 ATOM 3905 O OG1 . THR C 1 74 ? -47.515 28.857 -6.550 1.00 38.47 ? 69 THR M OG1 1 ATOM 3906 C CG2 . THR C 1 74 ? -48.796 30.563 -7.847 1.00 37.51 ? 69 THR M CG2 1 ATOM 3907 N N . ASP C 1 75 ? -49.966 32.153 -5.185 1.00 49.03 ? 70 ASP M N 1 ATOM 3908 C CA . ASP C 1 75 ? -49.776 33.555 -4.864 1.00 52.68 ? 70 ASP M CA 1 ATOM 3909 C C . ASP C 1 75 ? -50.724 33.845 -3.710 1.00 55.63 ? 70 ASP M C 1 ATOM 3910 O O . ASP C 1 75 ? -51.876 33.381 -3.718 1.00 55.04 ? 70 ASP M O 1 ATOM 3911 C CB . ASP C 1 75 ? -50.120 34.433 -6.074 1.00 52.59 ? 70 ASP M CB 1 ATOM 3912 C CG . ASP C 1 75 ? -50.458 35.911 -5.814 1.00 57.69 ? 70 ASP M CG 1 ATOM 3913 O OD1 . ASP C 1 75 ? -49.874 36.545 -4.928 1.00 60.16 ? 70 ASP M OD1 1 ATOM 3914 O OD2 . ASP C 1 75 ? -51.320 36.448 -6.516 1.00 59.72 ? 70 ASP M OD2 1 ATOM 3915 N N . PHE C 1 76 ? -50.179 34.570 -2.717 1.00 52.93 ? 71 PHE M N 1 ATOM 3916 C CA . PHE C 1 76 ? -50.880 35.007 -1.522 1.00 42.70 ? 71 PHE M CA 1 ATOM 3917 C C . PHE C 1 76 ? -50.535 36.458 -1.186 1.00 36.74 ? 71 PHE M C 1 ATOM 3918 O O . PHE C 1 76 ? -49.389 36.851 -1.450 1.00 32.49 ? 71 PHE M O 1 ATOM 3919 C CB . PHE C 1 76 ? -50.475 34.117 -0.403 1.00 39.58 ? 71 PHE M CB 1 ATOM 3920 C CG . PHE C 1 76 ? -50.723 32.672 -0.732 1.00 36.24 ? 71 PHE M CG 1 ATOM 3921 C CD1 . PHE C 1 76 ? -51.984 32.143 -0.565 1.00 36.95 ? 71 PHE M CD1 1 ATOM 3922 C CD2 . PHE C 1 76 ? -49.662 31.907 -1.158 1.00 34.73 ? 71 PHE M CD2 1 ATOM 3923 C CE1 . PHE C 1 76 ? -52.178 30.803 -0.821 1.00 40.73 ? 71 PHE M CE1 1 ATOM 3924 C CE2 . PHE C 1 76 ? -49.875 30.576 -1.410 1.00 36.23 ? 71 PHE M CE2 1 ATOM 3925 C CZ . PHE C 1 76 ? -51.122 30.021 -1.243 1.00 39.47 ? 71 PHE M CZ 1 ATOM 3926 N N . THR C 1 77 ? -51.456 37.224 -0.579 1.00 28.93 ? 72 THR M N 1 ATOM 3927 C CA . THR C 1 77 ? -51.251 38.635 -0.280 1.00 36.79 ? 72 THR M CA 1 ATOM 3928 C C . THR C 1 77 ? -51.806 39.133 1.075 1.00 41.44 ? 72 THR M C 1 ATOM 3929 O O . THR C 1 77 ? -53.019 39.065 1.309 1.00 44.62 ? 72 THR M O 1 ATOM 3930 C CB . THR C 1 77 ? -51.862 39.440 -1.451 1.00 38.19 ? 72 THR M CB 1 ATOM 3931 O OG1 . THR C 1 77 ? -51.163 39.012 -2.615 1.00 45.29 ? 72 THR M OG1 1 ATOM 3932 C CG2 . THR C 1 77 ? -51.750 40.954 -1.310 1.00 40.31 ? 72 THR M CG2 1 ATOM 3933 N N . LEU C 1 78 ? -50.967 39.596 2.017 1.00 39.98 ? 73 LEU M N 1 ATOM 3934 C CA . LEU C 1 78 ? -51.427 40.169 3.277 1.00 38.69 ? 73 LEU M CA 1 ATOM 3935 C C . LEU C 1 78 ? -51.755 41.619 2.956 1.00 38.58 ? 73 LEU M C 1 ATOM 3936 O O . LEU C 1 78 ? -50.999 42.270 2.220 1.00 35.82 ? 73 LEU M O 1 ATOM 3937 C CB . LEU C 1 78 ? -50.349 40.181 4.369 1.00 36.53 ? 73 LEU M CB 1 ATOM 3938 C CG . LEU C 1 78 ? -50.670 40.607 5.804 1.00 31.46 ? 73 LEU M CG 1 ATOM 3939 C CD1 . LEU C 1 78 ? -51.390 39.501 6.513 1.00 30.19 ? 73 LEU M CD1 1 ATOM 3940 C CD2 . LEU C 1 78 ? -49.418 40.795 6.609 1.00 31.41 ? 73 LEU M CD2 1 ATOM 3941 N N . LYS C 1 79 ? -52.879 42.104 3.482 1.00 39.40 ? 74 LYS M N 1 ATOM 3942 C CA . LYS C 1 79 ? -53.322 43.472 3.289 1.00 40.40 ? 74 LYS M CA 1 ATOM 3943 C C . LYS C 1 79 ? -53.591 44.025 4.674 1.00 36.74 ? 74 LYS M C 1 ATOM 3944 O O . LYS C 1 79 ? -54.296 43.351 5.435 1.00 37.15 ? 74 LYS M O 1 ATOM 3945 C CB . LYS C 1 79 ? -54.601 43.491 2.446 1.00 44.84 ? 74 LYS M CB 1 ATOM 3946 C CG . LYS C 1 79 ? -54.474 44.473 1.290 1.00 47.52 ? 74 LYS M CG 1 ATOM 3947 C CD . LYS C 1 79 ? -55.719 44.436 0.430 1.00 51.19 ? 74 LYS M CD 1 ATOM 3948 C CE . LYS C 1 79 ? -55.444 45.181 -0.872 1.00 52.09 ? 74 LYS M CE 1 ATOM 3949 N NZ . LYS C 1 79 ? -56.657 45.343 -1.652 1.00 54.08 ? 74 LYS M NZ 1 ATOM 3950 N N . ILE C 1 80 ? -53.030 45.199 5.010 1.00 32.78 ? 75 ILE M N 1 ATOM 3951 C CA . ILE C 1 80 ? -53.124 45.806 6.334 1.00 35.05 ? 75 ILE M CA 1 ATOM 3952 C C . ILE C 1 80 ? -53.876 47.116 6.145 1.00 35.42 ? 75 ILE M C 1 ATOM 3953 O O . ILE C 1 80 ? -53.259 48.103 5.766 1.00 42.81 ? 75 ILE M O 1 ATOM 3954 C CB . ILE C 1 80 ? -51.682 46.062 6.919 1.00 35.79 ? 75 ILE M CB 1 ATOM 3955 C CG1 . ILE C 1 80 ? -50.907 44.757 6.942 1.00 35.25 ? 75 ILE M CG1 1 ATOM 3956 C CG2 . ILE C 1 80 ? -51.762 46.642 8.348 1.00 36.37 ? 75 ILE M CG2 1 ATOM 3957 C CD1 . ILE C 1 80 ? -49.483 44.851 7.491 1.00 35.10 ? 75 ILE M CD1 1 ATOM 3958 N N . SER C 1 81 ? -55.176 47.207 6.380 1.00 34.01 ? 76 SER M N 1 ATOM 3959 C CA . SER C 1 81 ? -55.921 48.407 6.055 1.00 31.17 ? 76 SER M CA 1 ATOM 3960 C C . SER C 1 81 ? -55.610 49.765 6.580 1.00 30.94 ? 76 SER M C 1 ATOM 3961 O O . SER C 1 81 ? -55.272 50.622 5.778 1.00 37.31 ? 76 SER M O 1 ATOM 3962 C CB . SER C 1 81 ? -57.373 48.193 6.327 1.00 26.81 ? 76 SER M CB 1 ATOM 3963 O OG . SER C 1 81 ? -57.687 47.239 5.331 1.00 38.32 ? 76 SER M OG 1 ATOM 3964 N N . ARG C 1 82 ? -55.771 50.067 7.838 1.00 29.59 ? 77 ARG M N 1 ATOM 3965 C CA . ARG C 1 82 ? -55.537 51.430 8.233 1.00 29.67 ? 77 ARG M CA 1 ATOM 3966 C C . ARG C 1 82 ? -54.301 51.116 9.033 1.00 29.32 ? 77 ARG M C 1 ATOM 3967 O O . ARG C 1 82 ? -54.388 50.476 10.090 1.00 28.18 ? 77 ARG M O 1 ATOM 3968 C CB . ARG C 1 82 ? -56.691 51.938 9.108 1.00 36.26 ? 77 ARG M CB 1 ATOM 3969 C CG . ARG C 1 82 ? -58.096 52.144 8.496 1.00 41.35 ? 77 ARG M CG 1 ATOM 3970 C CD . ARG C 1 82 ? -59.136 52.036 9.645 1.00 50.43 ? 77 ARG M CD 1 ATOM 3971 N NE . ARG C 1 82 ? -60.491 52.500 9.343 1.00 53.13 ? 77 ARG M NE 1 ATOM 3972 C CZ . ARG C 1 82 ? -61.414 52.706 10.306 1.00 52.78 ? 77 ARG M CZ 1 ATOM 3973 N NH1 . ARG C 1 82 ? -61.172 52.453 11.598 1.00 48.58 ? 77 ARG M NH1 1 ATOM 3974 N NH2 . ARG C 1 82 ? -62.623 53.168 9.963 1.00 52.80 ? 77 ARG M NH2 1 ATOM 3975 N N . VAL C 1 83 ? -53.137 51.428 8.482 1.00 28.26 ? 78 VAL M N 1 ATOM 3976 C CA . VAL C 1 83 ? -51.906 51.175 9.209 1.00 26.61 ? 78 VAL M CA 1 ATOM 3977 C C . VAL C 1 83 ? -51.680 52.117 10.380 1.00 26.98 ? 78 VAL M C 1 ATOM 3978 O O . VAL C 1 83 ? -51.647 53.343 10.253 1.00 33.81 ? 78 VAL M O 1 ATOM 3979 C CB . VAL C 1 83 ? -50.718 51.247 8.248 1.00 23.37 ? 78 VAL M CB 1 ATOM 3980 C CG1 . VAL C 1 83 ? -49.392 51.158 8.990 1.00 28.78 ? 78 VAL M CG1 1 ATOM 3981 C CG2 . VAL C 1 83 ? -50.796 50.046 7.314 1.00 25.17 ? 78 VAL M CG2 1 ATOM 3982 N N . GLU C 1 84 ? -51.576 51.525 11.554 1.00 24.99 ? 79 GLU M N 1 ATOM 3983 C CA . GLU C 1 84 ? -51.226 52.239 12.759 1.00 25.28 ? 79 GLU M CA 1 ATOM 3984 C C . GLU C 1 84 ? -49.766 51.987 13.076 1.00 28.72 ? 79 GLU M C 1 ATOM 3985 O O . GLU C 1 84 ? -49.158 51.001 12.631 1.00 29.02 ? 79 GLU M O 1 ATOM 3986 C CB . GLU C 1 84 ? -52.032 51.757 13.915 1.00 23.43 ? 79 GLU M CB 1 ATOM 3987 C CG . GLU C 1 84 ? -53.495 51.992 13.676 1.00 25.00 ? 79 GLU M CG 1 ATOM 3988 C CD . GLU C 1 84 ? -54.421 51.302 14.657 1.00 30.24 ? 79 GLU M CD 1 ATOM 3989 O OE1 . GLU C 1 84 ? -53.983 50.694 15.642 1.00 32.92 ? 79 GLU M OE1 1 ATOM 3990 O OE2 . GLU C 1 84 ? -55.617 51.382 14.402 1.00 34.54 ? 79 GLU M OE2 1 ATOM 3991 N N . ALA C 1 85 ? -49.267 52.874 13.946 1.00 29.56 ? 80 ALA M N 1 ATOM 3992 C CA . ALA C 1 85 ? -47.894 52.851 14.420 1.00 26.57 ? 80 ALA M CA 1 ATOM 3993 C C . ALA C 1 85 ? -47.411 51.474 14.819 1.00 29.86 ? 80 ALA M C 1 ATOM 3994 O O . ALA C 1 85 ? -46.455 50.938 14.244 1.00 30.01 ? 80 ALA M O 1 ATOM 3995 C CB . ALA C 1 85 ? -47.734 53.740 15.620 1.00 23.89 ? 80 ALA M CB 1 ATOM 3996 N N . GLU C 1 86 ? -48.190 50.820 15.692 1.00 27.21 ? 81 GLU M N 1 ATOM 3997 C CA . GLU C 1 86 ? -47.825 49.504 16.209 1.00 24.39 ? 81 GLU M CA 1 ATOM 3998 C C . GLU C 1 86 ? -47.728 48.387 15.191 1.00 24.11 ? 81 GLU M C 1 ATOM 3999 O O . GLU C 1 86 ? -47.668 47.240 15.620 1.00 29.67 ? 81 GLU M O 1 ATOM 4000 C CB . GLU C 1 86 ? -48.814 49.073 17.271 1.00 26.69 ? 81 GLU M CB 1 ATOM 4001 C CG . GLU C 1 86 ? -48.608 49.749 18.611 1.00 37.95 ? 81 GLU M CG 1 ATOM 4002 C CD . GLU C 1 86 ? -48.579 51.273 18.571 1.00 43.22 ? 81 GLU M CD 1 ATOM 4003 O OE1 . GLU C 1 86 ? -49.557 51.897 18.151 1.00 45.06 ? 81 GLU M OE1 1 ATOM 4004 O OE2 . GLU C 1 86 ? -47.542 51.828 18.937 1.00 50.76 ? 81 GLU M OE2 1 ATOM 4005 N N . ASP C 1 87 ? -47.771 48.651 13.874 1.00 18.61 ? 82 ASP M N 1 ATOM 4006 C CA . ASP C 1 87 ? -47.708 47.598 12.898 1.00 8.90 ? 82 ASP M CA 1 ATOM 4007 C C . ASP C 1 87 ? -46.336 47.577 12.314 1.00 7.12 ? 82 ASP M C 1 ATOM 4008 O O . ASP C 1 87 ? -46.076 46.862 11.349 1.00 12.35 ? 82 ASP M O 1 ATOM 4009 C CB . ASP C 1 87 ? -48.715 47.835 11.807 1.00 17.04 ? 82 ASP M CB 1 ATOM 4010 C CG . ASP C 1 87 ? -50.193 47.906 12.211 1.00 20.47 ? 82 ASP M CG 1 ATOM 4011 O OD1 . ASP C 1 87 ? -50.706 47.099 12.999 1.00 21.98 ? 82 ASP M OD1 1 ATOM 4012 O OD2 . ASP C 1 87 ? -50.838 48.797 11.689 1.00 16.49 ? 82 ASP M OD2 1 ATOM 4013 N N . LEU C 1 88 ? -45.460 48.447 12.803 1.00 4.18 ? 83 LEU M N 1 ATOM 4014 C CA . LEU C 1 88 ? -44.053 48.378 12.461 1.00 6.89 ? 83 LEU M CA 1 ATOM 4015 C C . LEU C 1 88 ? -43.528 46.968 12.708 1.00 10.38 ? 83 LEU M C 1 ATOM 4016 O O . LEU C 1 88 ? -43.755 46.367 13.769 1.00 12.92 ? 83 LEU M O 1 ATOM 4017 C CB . LEU C 1 88 ? -43.191 49.197 13.338 1.00 12.00 ? 83 LEU M CB 1 ATOM 4018 C CG . LEU C 1 88 ? -43.098 50.652 13.255 1.00 19.44 ? 83 LEU M CG 1 ATOM 4019 C CD1 . LEU C 1 88 ? -43.278 51.315 14.631 1.00 22.64 ? 83 LEU M CD1 1 ATOM 4020 C CD2 . LEU C 1 88 ? -41.736 50.929 12.670 1.00 21.22 ? 83 LEU M CD2 1 ATOM 4021 N N . GLY C 1 89 ? -42.732 46.463 11.797 1.00 9.27 ? 84 GLY M N 1 ATOM 4022 C CA . GLY C 1 89 ? -42.076 45.209 12.028 1.00 8.47 ? 84 GLY M CA 1 ATOM 4023 C C . GLY C 1 89 ? -41.721 44.705 10.670 1.00 14.14 ? 84 GLY M C 1 ATOM 4024 O O . GLY C 1 89 ? -41.654 45.440 9.677 1.00 12.86 ? 84 GLY M O 1 ATOM 4025 N N . VAL C 1 90 ? -41.413 43.431 10.656 1.00 17.88 ? 85 VAL M N 1 ATOM 4026 C CA . VAL C 1 90 ? -41.244 42.791 9.387 1.00 16.68 ? 85 VAL M CA 1 ATOM 4027 C C . VAL C 1 90 ? -42.180 41.571 9.474 1.00 18.93 ? 85 VAL M C 1 ATOM 4028 O O . VAL C 1 90 ? -42.531 41.035 10.544 1.00 17.37 ? 85 VAL M O 1 ATOM 4029 C CB . VAL C 1 90 ? -39.689 42.480 9.138 1.00 14.83 ? 85 VAL M CB 1 ATOM 4030 C CG1 . VAL C 1 90 ? -38.818 43.212 10.142 1.00 16.78 ? 85 VAL M CG1 1 ATOM 4031 C CG2 . VAL C 1 90 ? -39.379 41.024 9.241 1.00 15.33 ? 85 VAL M CG2 1 ATOM 4032 N N . TYR C 1 91 ? -42.719 41.234 8.305 1.00 19.66 ? 86 TYR M N 1 ATOM 4033 C CA . TYR C 1 91 ? -43.689 40.158 8.162 1.00 15.85 ? 86 TYR M CA 1 ATOM 4034 C C . TYR C 1 91 ? -43.046 39.017 7.391 1.00 12.10 ? 86 TYR M C 1 ATOM 4035 O O . TYR C 1 91 ? -42.163 39.261 6.576 1.00 14.86 ? 86 TYR M O 1 ATOM 4036 C CB . TYR C 1 91 ? -44.921 40.736 7.442 1.00 16.06 ? 86 TYR M CB 1 ATOM 4037 C CG . TYR C 1 91 ? -45.671 41.819 8.217 1.00 14.01 ? 86 TYR M CG 1 ATOM 4038 C CD1 . TYR C 1 91 ? -45.231 43.125 8.242 1.00 11.62 ? 86 TYR M CD1 1 ATOM 4039 C CD2 . TYR C 1 91 ? -46.783 41.470 8.958 1.00 20.42 ? 86 TYR M CD2 1 ATOM 4040 C CE1 . TYR C 1 91 ? -45.893 44.073 9.005 1.00 14.40 ? 86 TYR M CE1 1 ATOM 4041 C CE2 . TYR C 1 91 ? -47.455 42.416 9.723 1.00 19.04 ? 86 TYR M CE2 1 ATOM 4042 C CZ . TYR C 1 91 ? -47.004 43.716 9.744 1.00 15.01 ? 86 TYR M CZ 1 ATOM 4043 O OH . TYR C 1 91 ? -47.667 44.643 10.514 1.00 7.51 ? 86 TYR M OH 1 ATOM 4044 N N . TYR C 1 92 ? -43.414 37.769 7.561 1.00 16.21 ? 87 TYR M N 1 ATOM 4045 C CA . TYR C 1 92 ? -42.753 36.644 6.915 1.00 20.53 ? 87 TYR M CA 1 ATOM 4046 C C . TYR C 1 92 ? -43.824 35.677 6.472 1.00 18.74 ? 87 TYR M C 1 ATOM 4047 O O . TYR C 1 92 ? -44.626 35.333 7.353 1.00 23.95 ? 87 TYR M O 1 ATOM 4048 C CB . TYR C 1 92 ? -41.843 35.847 7.875 1.00 24.96 ? 87 TYR M CB 1 ATOM 4049 C CG . TYR C 1 92 ? -40.623 36.567 8.423 1.00 27.49 ? 87 TYR M CG 1 ATOM 4050 C CD1 . TYR C 1 92 ? -39.452 36.574 7.705 1.00 24.84 ? 87 TYR M CD1 1 ATOM 4051 C CD2 . TYR C 1 92 ? -40.673 37.174 9.658 1.00 29.04 ? 87 TYR M CD2 1 ATOM 4052 C CE1 . TYR C 1 92 ? -38.320 37.180 8.213 1.00 26.29 ? 87 TYR M CE1 1 ATOM 4053 C CE2 . TYR C 1 92 ? -39.539 37.778 10.169 1.00 30.39 ? 87 TYR M CE2 1 ATOM 4054 C CZ . TYR C 1 92 ? -38.354 37.782 9.449 1.00 27.80 ? 87 TYR M CZ 1 ATOM 4055 O OH . TYR C 1 92 ? -37.204 38.375 9.978 1.00 22.79 ? 87 TYR M OH 1 ATOM 4056 N N . CYS C 1 93 ? -43.942 35.217 5.226 1.00 13.24 ? 88 CYS M N 1 ATOM 4057 C CA . CYS C 1 93 ? -44.955 34.208 4.984 1.00 15.36 ? 88 CYS M CA 1 ATOM 4058 C C . CYS C 1 93 ? -44.368 32.851 5.125 1.00 10.42 ? 88 CYS M C 1 ATOM 4059 O O . CYS C 1 93 ? -43.156 32.734 5.046 1.00 11.31 ? 88 CYS M O 1 ATOM 4060 C CB . CYS C 1 93 ? -45.511 34.304 3.634 1.00 22.56 ? 88 CYS M CB 1 ATOM 4061 S SG . CYS C 1 93 ? -44.257 34.193 2.354 1.00 31.94 ? 88 CYS M SG 1 ATOM 4062 N N . PHE C 1 94 ? -45.134 31.808 5.369 1.00 21.17 ? 89 PHE M N 1 ATOM 4063 C CA . PHE C 1 94 ? -44.565 30.469 5.551 1.00 24.17 ? 89 PHE M CA 1 ATOM 4064 C C . PHE C 1 94 ? -45.503 29.402 4.957 1.00 25.80 ? 89 PHE M C 1 ATOM 4065 O O . PHE C 1 94 ? -46.743 29.494 4.916 1.00 23.90 ? 89 PHE M O 1 ATOM 4066 C CB . PHE C 1 94 ? -44.282 30.302 7.083 1.00 17.27 ? 89 PHE M CB 1 ATOM 4067 C CG . PHE C 1 94 ? -44.360 28.932 7.752 1.00 15.46 ? 89 PHE M CG 1 ATOM 4068 C CD1 . PHE C 1 94 ? -45.569 28.348 8.036 1.00 15.05 ? 89 PHE M CD1 1 ATOM 4069 C CD2 . PHE C 1 94 ? -43.221 28.260 8.097 1.00 15.68 ? 89 PHE M CD2 1 ATOM 4070 C CE1 . PHE C 1 94 ? -45.641 27.115 8.649 1.00 15.77 ? 89 PHE M CE1 1 ATOM 4071 C CE2 . PHE C 1 94 ? -43.300 27.032 8.709 1.00 10.94 ? 89 PHE M CE2 1 ATOM 4072 C CZ . PHE C 1 94 ? -44.499 26.446 8.990 1.00 12.75 ? 89 PHE M CZ 1 ATOM 4073 N N . GLN C 1 95 ? -44.780 28.438 4.405 1.00 23.79 ? 90 GLN M N 1 ATOM 4074 C CA . GLN C 1 95 ? -45.278 27.277 3.700 1.00 24.48 ? 90 GLN M CA 1 ATOM 4075 C C . GLN C 1 95 ? -45.215 26.142 4.713 1.00 26.00 ? 90 GLN M C 1 ATOM 4076 O O . GLN C 1 95 ? -44.104 25.843 5.200 1.00 16.98 ? 90 GLN M O 1 ATOM 4077 C CB . GLN C 1 95 ? -44.316 27.118 2.518 1.00 26.92 ? 90 GLN M CB 1 ATOM 4078 C CG . GLN C 1 95 ? -44.218 25.955 1.563 1.00 20.50 ? 90 GLN M CG 1 ATOM 4079 C CD . GLN C 1 95 ? -44.098 24.652 2.303 1.00 22.15 ? 90 GLN M CD 1 ATOM 4080 O OE1 . GLN C 1 95 ? -45.152 24.027 2.432 1.00 30.07 ? 90 GLN M OE1 1 ATOM 4081 N NE2 . GLN C 1 95 ? -42.985 24.203 2.872 1.00 15.35 ? 90 GLN M NE2 1 ATOM 4082 N N . GLY C 1 96 ? -46.352 25.485 4.946 1.00 25.26 ? 91 GLY M N 1 ATOM 4083 C CA . GLY C 1 96 ? -46.383 24.331 5.849 1.00 37.55 ? 91 GLY M CA 1 ATOM 4084 C C . GLY C 1 96 ? -46.770 22.995 5.189 1.00 39.76 ? 91 GLY M C 1 ATOM 4085 O O . GLY C 1 96 ? -46.474 21.886 5.659 1.00 39.28 ? 91 GLY M O 1 ATOM 4086 N N . SER C 1 97 ? -47.408 23.106 4.019 1.00 41.22 ? 92 SER M N 1 ATOM 4087 C CA . SER C 1 97 ? -47.941 21.987 3.261 1.00 38.04 ? 92 SER M CA 1 ATOM 4088 C C . SER C 1 97 ? -46.869 21.080 2.637 1.00 41.14 ? 92 SER M C 1 ATOM 4089 O O . SER C 1 97 ? -47.161 20.278 1.744 1.00 45.74 ? 92 SER M O 1 ATOM 4090 C CB . SER C 1 97 ? -48.870 22.553 2.143 1.00 36.14 ? 92 SER M CB 1 ATOM 4091 O OG . SER C 1 97 ? -49.270 23.937 2.088 1.00 22.84 ? 92 SER M OG 1 ATOM 4092 N N . HIS C 1 98 ? -45.592 21.138 2.998 1.00 45.06 ? 93 HIS M N 1 ATOM 4093 C CA . HIS C 1 98 ? -44.514 20.404 2.340 1.00 41.86 ? 93 HIS M CA 1 ATOM 4094 C C . HIS C 1 98 ? -43.353 20.299 3.290 1.00 41.03 ? 93 HIS M C 1 ATOM 4095 O O . HIS C 1 98 ? -43.263 21.056 4.256 1.00 45.10 ? 93 HIS M O 1 ATOM 4096 C CB . HIS C 1 98 ? -43.994 21.115 1.074 1.00 36.16 ? 93 HIS M CB 1 ATOM 4097 C CG . HIS C 1 98 ? -44.991 20.960 -0.063 1.00 37.33 ? 93 HIS M CG 1 ATOM 4098 N ND1 . HIS C 1 98 ? -45.902 21.837 -0.500 1.00 35.26 ? 93 HIS M ND1 1 ATOM 4099 C CD2 . HIS C 1 98 ? -45.165 19.784 -0.757 1.00 36.56 ? 93 HIS M CD2 1 ATOM 4100 C CE1 . HIS C 1 98 ? -46.628 21.248 -1.416 1.00 35.19 ? 93 HIS M CE1 1 ATOM 4101 N NE2 . HIS C 1 98 ? -46.171 20.019 -1.554 1.00 38.57 ? 93 HIS M NE2 1 ATOM 4102 N N . VAL C 1 99 ? -42.495 19.311 3.100 1.00 39.17 ? 94 VAL M N 1 ATOM 4103 C CA . VAL C 1 99 ? -41.256 19.324 3.835 1.00 37.05 ? 94 VAL M CA 1 ATOM 4104 C C . VAL C 1 99 ? -40.243 20.019 2.919 1.00 37.42 ? 94 VAL M C 1 ATOM 4105 O O . VAL C 1 99 ? -40.417 20.159 1.699 1.00 38.30 ? 94 VAL M O 1 ATOM 4106 C CB . VAL C 1 99 ? -40.920 17.873 4.184 1.00 36.83 ? 94 VAL M CB 1 ATOM 4107 C CG1 . VAL C 1 99 ? -39.492 17.638 4.660 1.00 40.44 ? 94 VAL M CG1 1 ATOM 4108 C CG2 . VAL C 1 99 ? -41.800 17.549 5.381 1.00 37.49 ? 94 VAL M CG2 1 ATOM 4109 N N . PRO C 1 100 ? -39.221 20.644 3.462 1.00 37.17 ? 95 PRO M N 1 ATOM 4110 C CA . PRO C 1 100 ? -39.294 21.352 4.711 1.00 36.84 ? 95 PRO M CA 1 ATOM 4111 C C . PRO C 1 100 ? -40.232 22.551 4.552 1.00 37.16 ? 95 PRO M C 1 ATOM 4112 O O . PRO C 1 100 ? -40.485 23.003 3.414 1.00 35.62 ? 95 PRO M O 1 ATOM 4113 C CB . PRO C 1 100 ? -37.838 21.685 4.965 1.00 41.81 ? 95 PRO M CB 1 ATOM 4114 C CG . PRO C 1 100 ? -37.042 20.648 4.204 1.00 40.66 ? 95 PRO M CG 1 ATOM 4115 C CD . PRO C 1 100 ? -37.865 20.624 2.939 1.00 40.42 ? 95 PRO M CD 1 ATOM 4116 N N . PRO C 1 101 ? -40.793 22.987 5.703 1.00 35.40 ? 96 PRO M N 1 ATOM 4117 C CA . PRO C 1 101 ? -41.482 24.263 5.904 1.00 32.01 ? 96 PRO M CA 1 ATOM 4118 C C . PRO C 1 101 ? -40.650 25.443 5.419 1.00 27.84 ? 96 PRO M C 1 ATOM 4119 O O . PRO C 1 101 ? -39.448 25.510 5.689 1.00 31.85 ? 96 PRO M O 1 ATOM 4120 C CB . PRO C 1 101 ? -41.746 24.284 7.397 1.00 30.92 ? 96 PRO M CB 1 ATOM 4121 C CG . PRO C 1 101 ? -41.916 22.869 7.808 1.00 28.14 ? 96 PRO M CG 1 ATOM 4122 C CD . PRO C 1 101 ? -40.833 22.221 6.952 1.00 34.94 ? 96 PRO M CD 1 ATOM 4123 N N . THR C 1 102 ? -41.228 26.445 4.803 1.00 24.21 ? 97 THR M N 1 ATOM 4124 C CA . THR C 1 102 ? -40.392 27.471 4.235 1.00 25.11 ? 97 THR M CA 1 ATOM 4125 C C . THR C 1 102 ? -40.910 28.860 4.481 1.00 29.08 ? 97 THR M C 1 ATOM 4126 O O . THR C 1 102 ? -42.062 29.211 4.203 1.00 31.16 ? 97 THR M O 1 ATOM 4127 C CB . THR C 1 102 ? -40.276 27.261 2.770 1.00 29.02 ? 97 THR M CB 1 ATOM 4128 O OG1 . THR C 1 102 ? -40.047 25.873 2.555 1.00 29.64 ? 97 THR M OG1 1 ATOM 4129 C CG2 . THR C 1 102 ? -39.169 28.131 2.199 1.00 36.57 ? 97 THR M CG2 1 ATOM 4130 N N . PHE C 1 103 ? -39.985 29.607 5.058 1.00 29.70 ? 98 PHE M N 1 ATOM 4131 C CA . PHE C 1 103 ? -40.213 30.976 5.442 1.00 20.46 ? 98 PHE M CA 1 ATOM 4132 C C . PHE C 1 103 ? -39.808 31.793 4.260 1.00 17.05 ? 98 PHE M C 1 ATOM 4133 O O . PHE C 1 103 ? -39.106 31.286 3.390 1.00 14.09 ? 98 PHE M O 1 ATOM 4134 C CB . PHE C 1 103 ? -39.356 31.325 6.635 1.00 19.32 ? 98 PHE M CB 1 ATOM 4135 C CG . PHE C 1 103 ? -39.924 30.866 7.984 1.00 15.52 ? 98 PHE M CG 1 ATOM 4136 C CD1 . PHE C 1 103 ? -41.037 31.510 8.523 1.00 15.00 ? 98 PHE M CD1 1 ATOM 4137 C CD2 . PHE C 1 103 ? -39.294 29.839 8.670 1.00 7.92 ? 98 PHE M CD2 1 ATOM 4138 C CE1 . PHE C 1 103 ? -41.505 31.110 9.758 1.00 18.79 ? 98 PHE M CE1 1 ATOM 4139 C CE2 . PHE C 1 103 ? -39.774 29.457 9.902 1.00 12.23 ? 98 PHE M CE2 1 ATOM 4140 C CZ . PHE C 1 103 ? -40.870 30.086 10.448 1.00 17.34 ? 98 PHE M CZ 1 ATOM 4141 N N . GLY C 1 104 ? -40.367 32.995 4.231 1.00 19.87 ? 99 GLY M N 1 ATOM 4142 C CA . GLY C 1 104 ? -40.098 33.983 3.210 1.00 18.00 ? 99 GLY M CA 1 ATOM 4143 C C . GLY C 1 104 ? -38.932 34.862 3.626 1.00 22.13 ? 99 GLY M C 1 ATOM 4144 O O . GLY C 1 104 ? -38.184 34.651 4.594 1.00 25.93 ? 99 GLY M O 1 ATOM 4145 N N . GLY C 1 105 ? -38.819 35.935 2.880 1.00 20.12 ? 100 GLY M N 1 ATOM 4146 C CA . GLY C 1 105 ? -37.693 36.814 3.088 1.00 15.98 ? 100 GLY M CA 1 ATOM 4147 C C . GLY C 1 105 ? -37.986 37.931 4.053 1.00 15.39 ? 100 GLY M C 1 ATOM 4148 O O . GLY C 1 105 ? -37.032 38.524 4.529 1.00 18.25 ? 100 GLY M O 1 ATOM 4149 N N . GLY C 1 106 ? -39.236 38.289 4.349 1.00 14.51 ? 101 GLY M N 1 ATOM 4150 C CA . GLY C 1 106 ? -39.458 39.374 5.285 1.00 13.36 ? 101 GLY M CA 1 ATOM 4151 C C . GLY C 1 106 ? -39.715 40.645 4.532 1.00 10.57 ? 101 GLY M C 1 ATOM 4152 O O . GLY C 1 106 ? -39.094 40.922 3.523 1.00 14.11 ? 101 GLY M O 1 ATOM 4153 N N . THR C 1 107 ? -40.713 41.384 4.969 1.00 14.69 ? 102 THR M N 1 ATOM 4154 C CA . THR C 1 107 ? -41.072 42.664 4.386 1.00 22.90 ? 102 THR M CA 1 ATOM 4155 C C . THR C 1 107 ? -41.024 43.681 5.545 1.00 25.97 ? 102 THR M C 1 ATOM 4156 O O . THR C 1 107 ? -41.694 43.469 6.564 1.00 29.57 ? 102 THR M O 1 ATOM 4157 C CB . THR C 1 107 ? -42.478 42.496 3.771 1.00 24.44 ? 102 THR M CB 1 ATOM 4158 O OG1 . THR C 1 107 ? -42.362 41.460 2.792 1.00 23.81 ? 102 THR M OG1 1 ATOM 4159 C CG2 . THR C 1 107 ? -43.033 43.797 3.192 1.00 26.89 ? 102 THR M CG2 1 ATOM 4160 N N . LYS C 1 108 ? -40.237 44.753 5.489 1.00 23.11 ? 103 LYS M N 1 ATOM 4161 C CA . LYS C 1 108 ? -40.125 45.658 6.598 1.00 23.21 ? 103 LYS M CA 1 ATOM 4162 C C . LYS C 1 108 ? -41.118 46.773 6.340 1.00 19.32 ? 103 LYS M C 1 ATOM 4163 O O . LYS C 1 108 ? -40.979 47.476 5.344 1.00 21.57 ? 103 LYS M O 1 ATOM 4164 C CB . LYS C 1 108 ? -38.689 46.170 6.666 1.00 23.83 ? 103 LYS M CB 1 ATOM 4165 C CG . LYS C 1 108 ? -38.267 46.688 8.046 1.00 32.88 ? 103 LYS M CG 1 ATOM 4166 C CD . LYS C 1 108 ? -38.957 47.963 8.565 1.00 40.80 ? 103 LYS M CD 1 ATOM 4167 C CE . LYS C 1 108 ? -38.693 48.242 10.061 1.00 48.72 ? 103 LYS M CE 1 ATOM 4168 N NZ . LYS C 1 108 ? -39.207 49.533 10.512 1.00 49.29 ? 103 LYS M NZ 1 ATOM 4169 N N . LEU C 1 109 ? -42.105 46.919 7.219 1.00 13.57 ? 104 LEU M N 1 ATOM 4170 C CA . LEU C 1 109 ? -43.131 47.937 7.141 1.00 11.92 ? 104 LEU M CA 1 ATOM 4171 C C . LEU C 1 109 ? -42.444 49.107 7.798 1.00 13.06 ? 104 LEU M C 1 ATOM 4172 O O . LEU C 1 109 ? -42.103 48.979 8.976 1.00 18.50 ? 104 LEU M O 1 ATOM 4173 C CB . LEU C 1 109 ? -44.336 47.519 7.969 1.00 11.90 ? 104 LEU M CB 1 ATOM 4174 C CG . LEU C 1 109 ? -45.750 48.070 7.927 1.00 10.19 ? 104 LEU M CG 1 ATOM 4175 C CD1 . LEU C 1 109 ? -45.763 49.557 7.880 1.00 10.30 ? 104 LEU M CD1 1 ATOM 4176 C CD2 . LEU C 1 109 ? -46.412 47.591 6.670 1.00 16.51 ? 104 LEU M CD2 1 ATOM 4177 N N . GLU C 1 110 ? -42.163 50.228 7.146 1.00 20.74 ? 105 GLU M N 1 ATOM 4178 C CA . GLU C 1 110 ? -41.608 51.343 7.907 1.00 25.89 ? 105 GLU M CA 1 ATOM 4179 C C . GLU C 1 110 ? -42.605 52.472 7.717 1.00 24.75 ? 105 GLU M C 1 ATOM 4180 O O . GLU C 1 110 ? -43.159 52.685 6.628 1.00 24.90 ? 105 GLU M O 1 ATOM 4181 C CB . GLU C 1 110 ? -40.220 51.790 7.426 1.00 25.62 ? 105 GLU M CB 1 ATOM 4182 C CG . GLU C 1 110 ? -40.132 52.372 6.054 1.00 36.10 ? 105 GLU M CG 1 ATOM 4183 C CD . GLU C 1 110 ? -38.775 52.963 5.831 1.00 42.60 ? 105 GLU M CD 1 ATOM 4184 O OE1 . GLU C 1 110 ? -37.865 52.199 5.520 1.00 50.43 ? 105 GLU M OE1 1 ATOM 4185 O OE2 . GLU C 1 110 ? -38.635 54.173 5.979 1.00 46.59 ? 105 GLU M OE2 1 ATOM 4186 N N . ILE C 1 111 ? -42.891 53.175 8.801 1.00 18.80 ? 106 ILE M N 1 ATOM 4187 C CA . ILE C 1 111 ? -43.933 54.172 8.774 1.00 16.26 ? 106 ILE M CA 1 ATOM 4188 C C . ILE C 1 111 ? -43.374 55.434 8.187 1.00 17.97 ? 106 ILE M C 1 ATOM 4189 O O . ILE C 1 111 ? -42.411 55.941 8.750 1.00 21.08 ? 106 ILE M O 1 ATOM 4190 C CB . ILE C 1 111 ? -44.402 54.350 10.202 1.00 14.13 ? 106 ILE M CB 1 ATOM 4191 C CG1 . ILE C 1 111 ? -45.160 53.105 10.569 1.00 8.53 ? 106 ILE M CG1 1 ATOM 4192 C CG2 . ILE C 1 111 ? -45.231 55.606 10.376 1.00 8.16 ? 106 ILE M CG2 1 ATOM 4193 C CD1 . ILE C 1 111 ? -45.174 53.283 12.085 1.00 14.88 ? 106 ILE M CD1 1 ATOM 4194 N N . LYS C 1 112 ? -43.909 55.903 7.056 1.00 20.76 ? 107 LYS M N 1 ATOM 4195 C CA . LYS C 1 112 ? -43.450 57.162 6.496 1.00 25.63 ? 107 LYS M CA 1 ATOM 4196 C C . LYS C 1 112 ? -43.624 58.257 7.541 1.00 23.45 ? 107 LYS M C 1 ATOM 4197 O O . LYS C 1 112 ? -44.457 58.180 8.448 1.00 18.38 ? 107 LYS M O 1 ATOM 4198 C CB . LYS C 1 112 ? -44.231 57.591 5.272 1.00 27.84 ? 107 LYS M CB 1 ATOM 4199 C CG . LYS C 1 112 ? -43.861 56.924 3.992 1.00 33.38 ? 107 LYS M CG 1 ATOM 4200 C CD . LYS C 1 112 ? -44.556 57.753 2.920 1.00 43.68 ? 107 LYS M CD 1 ATOM 4201 C CE . LYS C 1 112 ? -44.446 57.201 1.497 1.00 50.06 ? 107 LYS M CE 1 ATOM 4202 N NZ . LYS C 1 112 ? -43.147 57.434 0.886 1.00 53.61 ? 107 LYS M NZ 1 ATOM 4203 N N . ARG C 1 113 ? -42.885 59.335 7.415 1.00 26.82 ? 108 ARG M N 1 ATOM 4204 C CA . ARG C 1 113 ? -42.872 60.296 8.500 1.00 31.50 ? 108 ARG M CA 1 ATOM 4205 C C . ARG C 1 113 ? -42.518 61.632 7.900 1.00 33.15 ? 108 ARG M C 1 ATOM 4206 O O . ARG C 1 113 ? -41.939 61.714 6.805 1.00 36.54 ? 108 ARG M O 1 ATOM 4207 C CB . ARG C 1 113 ? -41.808 59.868 9.532 1.00 29.40 ? 108 ARG M CB 1 ATOM 4208 C CG . ARG C 1 113 ? -41.769 60.687 10.773 1.00 21.32 ? 108 ARG M CG 1 ATOM 4209 C CD . ARG C 1 113 ? -40.390 60.858 11.296 1.00 15.82 ? 108 ARG M CD 1 ATOM 4210 N NE . ARG C 1 113 ? -40.580 61.516 12.580 1.00 21.47 ? 108 ARG M NE 1 ATOM 4211 C CZ . ARG C 1 113 ? -40.729 62.851 12.750 1.00 23.31 ? 108 ARG M CZ 1 ATOM 4212 N NH1 . ARG C 1 113 ? -40.606 63.711 11.738 1.00 22.99 ? 108 ARG M NH1 1 ATOM 4213 N NH2 . ARG C 1 113 ? -40.942 63.363 13.980 1.00 23.58 ? 108 ARG M NH2 1 ATOM 4214 N N . ALA C 1 114 ? -42.909 62.689 8.617 1.00 33.67 ? 109 ALA M N 1 ATOM 4215 C CA . ALA C 1 114 ? -42.488 64.037 8.260 1.00 37.18 ? 109 ALA M CA 1 ATOM 4216 C C . ALA C 1 114 ? -40.969 63.943 8.224 1.00 36.28 ? 109 ALA M C 1 ATOM 4217 O O . ALA C 1 114 ? -40.416 63.268 9.093 1.00 35.64 ? 109 ALA M O 1 ATOM 4218 C CB . ALA C 1 114 ? -42.891 65.025 9.340 1.00 36.49 ? 109 ALA M CB 1 ATOM 4219 N N . ASP C 1 115 ? -40.269 64.452 7.211 1.00 35.86 ? 110 ASP M N 1 ATOM 4220 C CA . ASP C 1 115 ? -38.811 64.339 7.230 1.00 34.42 ? 110 ASP M CA 1 ATOM 4221 C C . ASP C 1 115 ? -38.287 65.103 8.455 1.00 35.94 ? 110 ASP M C 1 ATOM 4222 O O . ASP C 1 115 ? -38.988 65.973 9.031 1.00 28.98 ? 110 ASP M O 1 ATOM 4223 C CB . ASP C 1 115 ? -38.179 64.922 5.955 1.00 28.18 ? 110 ASP M CB 1 ATOM 4224 C CG . ASP C 1 115 ? -38.827 64.400 4.701 1.00 29.94 ? 110 ASP M CG 1 ATOM 4225 O OD1 . ASP C 1 115 ? -39.839 64.982 4.339 1.00 40.17 ? 110 ASP M OD1 1 ATOM 4226 O OD2 . ASP C 1 115 ? -38.359 63.435 4.098 1.00 22.79 ? 110 ASP M OD2 1 ATOM 4227 N N . ALA C 1 116 ? -37.061 64.688 8.850 1.00 34.31 ? 111 ALA M N 1 ATOM 4228 C CA . ALA C 1 116 ? -36.363 65.278 9.987 1.00 31.01 ? 111 ALA M CA 1 ATOM 4229 C C . ALA C 1 116 ? -34.880 65.203 9.721 1.00 28.81 ? 111 ALA M C 1 ATOM 4230 O O . ALA C 1 116 ? -34.372 64.357 8.967 1.00 28.84 ? 111 ALA M O 1 ATOM 4231 C CB . ALA C 1 116 ? -36.634 64.536 11.288 1.00 30.03 ? 111 ALA M CB 1 ATOM 4232 N N . ALA C 1 117 ? -34.190 66.135 10.349 1.00 29.43 ? 112 ALA M N 1 ATOM 4233 C CA . ALA C 1 117 ? -32.777 66.314 10.093 1.00 27.13 ? 112 ALA M CA 1 ATOM 4234 C C . ALA C 1 117 ? -31.943 65.851 11.278 1.00 24.04 ? 112 ALA M C 1 ATOM 4235 O O . ALA C 1 117 ? -32.325 66.106 12.436 1.00 25.24 ? 112 ALA M O 1 ATOM 4236 C CB . ALA C 1 117 ? -32.517 67.777 9.849 1.00 32.45 ? 112 ALA M CB 1 ATOM 4237 N N . PRO C 1 118 ? -30.817 65.172 11.010 1.00 11.93 ? 113 PRO M N 1 ATOM 4238 C CA . PRO C 1 118 ? -29.955 64.627 12.032 1.00 6.22 ? 113 PRO M CA 1 ATOM 4239 C C . PRO C 1 118 ? -29.343 65.568 13.060 1.00 11.30 ? 113 PRO M C 1 ATOM 4240 O O . PRO C 1 118 ? -28.562 66.455 12.707 1.00 21.04 ? 113 PRO M O 1 ATOM 4241 C CB . PRO C 1 118 ? -28.906 63.871 11.239 1.00 2.00 ? 113 PRO M CB 1 ATOM 4242 C CG . PRO C 1 118 ? -28.791 64.660 9.990 1.00 7.27 ? 113 PRO M CG 1 ATOM 4243 C CD . PRO C 1 118 ? -30.290 64.877 9.695 1.00 8.95 ? 113 PRO M CD 1 ATOM 4244 N N . THR C 1 119 ? -29.648 65.367 14.336 1.00 12.59 ? 114 THR M N 1 ATOM 4245 C CA . THR C 1 119 ? -28.966 66.013 15.449 1.00 16.84 ? 114 THR M CA 1 ATOM 4246 C C . THR C 1 119 ? -27.577 65.354 15.614 1.00 16.45 ? 114 THR M C 1 ATOM 4247 O O . THR C 1 119 ? -27.377 64.299 16.251 1.00 19.72 ? 114 THR M O 1 ATOM 4248 C CB . THR C 1 119 ? -29.898 65.816 16.631 1.00 24.44 ? 114 THR M CB 1 ATOM 4249 O OG1 . THR C 1 119 ? -31.201 66.212 16.189 1.00 37.11 ? 114 THR M OG1 1 ATOM 4250 C CG2 . THR C 1 119 ? -29.480 66.609 17.837 1.00 27.59 ? 114 THR M CG2 1 ATOM 4251 N N . VAL C 1 120 ? -26.586 65.977 14.987 1.00 12.30 ? 115 VAL M N 1 ATOM 4252 C CA . VAL C 1 120 ? -25.242 65.425 14.902 1.00 14.54 ? 115 VAL M CA 1 ATOM 4253 C C . VAL C 1 120 ? -24.336 65.792 16.062 1.00 20.64 ? 115 VAL M C 1 ATOM 4254 O O . VAL C 1 120 ? -24.395 66.932 16.536 1.00 18.76 ? 115 VAL M O 1 ATOM 4255 C CB . VAL C 1 120 ? -24.616 65.896 13.614 1.00 10.26 ? 115 VAL M CB 1 ATOM 4256 C CG1 . VAL C 1 120 ? -23.199 65.374 13.415 1.00 2.00 ? 115 VAL M CG1 1 ATOM 4257 C CG2 . VAL C 1 120 ? -25.565 65.444 12.519 1.00 14.21 ? 115 VAL M CG2 1 ATOM 4258 N N . SER C 1 121 ? -23.500 64.852 16.532 1.00 24.38 ? 116 SER M N 1 ATOM 4259 C CA . SER C 1 121 ? -22.534 65.158 17.574 1.00 20.63 ? 116 SER M CA 1 ATOM 4260 C C . SER C 1 121 ? -21.193 64.473 17.355 1.00 15.58 ? 116 SER M C 1 ATOM 4261 O O . SER C 1 121 ? -21.243 63.283 17.041 1.00 22.58 ? 116 SER M O 1 ATOM 4262 C CB . SER C 1 121 ? -23.123 64.744 18.867 1.00 20.75 ? 116 SER M CB 1 ATOM 4263 O OG . SER C 1 121 ? -22.351 65.500 19.774 1.00 29.92 ? 116 SER M OG 1 ATOM 4264 N N . ILE C 1 122 ? -20.015 65.119 17.478 1.00 10.93 ? 117 ILE M N 1 ATOM 4265 C CA . ILE C 1 122 ? -18.749 64.446 17.178 1.00 10.69 ? 117 ILE M CA 1 ATOM 4266 C C . ILE C 1 122 ? -17.917 64.403 18.446 1.00 15.53 ? 117 ILE M C 1 ATOM 4267 O O . ILE C 1 122 ? -17.875 65.396 19.196 1.00 14.40 ? 117 ILE M O 1 ATOM 4268 C CB . ILE C 1 122 ? -17.985 65.183 16.063 1.00 7.23 ? 117 ILE M CB 1 ATOM 4269 C CG1 . ILE C 1 122 ? -16.817 64.326 15.670 1.00 11.53 ? 117 ILE M CG1 1 ATOM 4270 C CG2 . ILE C 1 122 ? -17.434 66.514 16.497 1.00 3.45 ? 117 ILE M CG2 1 ATOM 4271 C CD1 . ILE C 1 122 ? -15.907 64.929 14.575 1.00 13.58 ? 117 ILE M CD1 1 ATOM 4272 N N . PHE C 1 123 ? -17.240 63.284 18.709 1.00 13.70 ? 118 PHE M N 1 ATOM 4273 C CA . PHE C 1 123 ? -16.524 63.137 19.975 1.00 14.06 ? 118 PHE M CA 1 ATOM 4274 C C . PHE C 1 123 ? -15.099 62.637 19.763 1.00 9.94 ? 118 PHE M C 1 ATOM 4275 O O . PHE C 1 123 ? -14.862 61.699 18.995 1.00 7.48 ? 118 PHE M O 1 ATOM 4276 C CB . PHE C 1 123 ? -17.270 62.165 20.877 1.00 18.10 ? 118 PHE M CB 1 ATOM 4277 C CG . PHE C 1 123 ? -18.688 62.557 21.288 1.00 19.99 ? 118 PHE M CG 1 ATOM 4278 C CD1 . PHE C 1 123 ? -19.755 62.329 20.428 1.00 20.17 ? 118 PHE M CD1 1 ATOM 4279 C CD2 . PHE C 1 123 ? -18.905 63.104 22.541 1.00 17.02 ? 118 PHE M CD2 1 ATOM 4280 C CE1 . PHE C 1 123 ? -21.028 62.653 20.846 1.00 19.74 ? 118 PHE M CE1 1 ATOM 4281 C CE2 . PHE C 1 123 ? -20.178 63.422 22.952 1.00 14.87 ? 118 PHE M CE2 1 ATOM 4282 C CZ . PHE C 1 123 ? -21.238 63.196 22.107 1.00 19.90 ? 118 PHE M CZ 1 ATOM 4283 N N . PRO C 1 124 ? -14.096 63.307 20.306 1.00 11.61 ? 119 PRO M N 1 ATOM 4284 C CA . PRO C 1 124 ? -12.699 62.882 20.237 1.00 14.22 ? 119 PRO M CA 1 ATOM 4285 C C . PRO C 1 124 ? -12.431 61.582 20.997 1.00 15.96 ? 119 PRO M C 1 ATOM 4286 O O . PRO C 1 124 ? -13.299 61.055 21.705 1.00 13.14 ? 119 PRO M O 1 ATOM 4287 C CB . PRO C 1 124 ? -11.905 64.054 20.790 1.00 15.10 ? 119 PRO M CB 1 ATOM 4288 C CG . PRO C 1 124 ? -12.911 64.756 21.672 1.00 19.13 ? 119 PRO M CG 1 ATOM 4289 C CD . PRO C 1 124 ? -14.241 64.609 20.932 1.00 13.88 ? 119 PRO M CD 1 ATOM 4290 N N . PRO C 1 125 ? -11.234 61.004 20.882 1.00 13.86 ? 120 PRO M N 1 ATOM 4291 C CA . PRO C 1 125 ? -10.815 59.857 21.662 1.00 8.85 ? 120 PRO M CA 1 ATOM 4292 C C . PRO C 1 125 ? -10.737 60.220 23.114 1.00 8.41 ? 120 PRO M C 1 ATOM 4293 O O . PRO C 1 125 ? -10.547 61.399 23.447 1.00 8.36 ? 120 PRO M O 1 ATOM 4294 C CB . PRO C 1 125 ? -9.492 59.494 21.095 1.00 9.46 ? 120 PRO M CB 1 ATOM 4295 C CG . PRO C 1 125 ? -9.671 59.853 19.654 1.00 11.20 ? 120 PRO M CG 1 ATOM 4296 C CD . PRO C 1 125 ? -10.289 61.229 19.802 1.00 14.58 ? 120 PRO M CD 1 ATOM 4297 N N . SER C 1 126 ? -10.873 59.238 23.998 1.00 8.40 ? 121 SER M N 1 ATOM 4298 C CA . SER C 1 126 ? -10.645 59.589 25.379 1.00 10.58 ? 121 SER M CA 1 ATOM 4299 C C . SER C 1 126 ? -9.177 59.314 25.729 1.00 18.73 ? 121 SER M C 1 ATOM 4300 O O . SER C 1 126 ? -8.491 58.518 25.067 1.00 23.78 ? 121 SER M O 1 ATOM 4301 C CB . SER C 1 126 ? -11.614 58.792 26.249 1.00 2.00 ? 121 SER M CB 1 ATOM 4302 O OG . SER C 1 126 ? -11.478 57.390 26.096 1.00 11.03 ? 121 SER M OG 1 ATOM 4303 N N . SER C 1 127 ? -8.654 59.944 26.777 1.00 23.51 ? 122 SER M N 1 ATOM 4304 C CA . SER C 1 127 ? -7.326 59.646 27.301 1.00 29.25 ? 122 SER M CA 1 ATOM 4305 C C . SER C 1 127 ? -7.244 58.145 27.592 1.00 28.70 ? 122 SER M C 1 ATOM 4306 O O . SER C 1 127 ? -6.310 57.476 27.151 1.00 29.94 ? 122 SER M O 1 ATOM 4307 C CB . SER C 1 127 ? -7.100 60.443 28.589 1.00 29.66 ? 122 SER M CB 1 ATOM 4308 O OG . SER C 1 127 ? -8.273 60.317 29.396 1.00 38.44 ? 122 SER M OG 1 ATOM 4309 N N . GLU C 1 128 ? -8.315 57.630 28.224 1.00 26.25 ? 123 GLU M N 1 ATOM 4310 C CA . GLU C 1 128 ? -8.401 56.239 28.585 1.00 28.27 ? 123 GLU M CA 1 ATOM 4311 C C . GLU C 1 128 ? -8.138 55.397 27.351 1.00 24.62 ? 123 GLU M C 1 ATOM 4312 O O . GLU C 1 128 ? -7.332 54.469 27.403 1.00 30.44 ? 123 GLU M O 1 ATOM 4313 C CB . GLU C 1 128 ? -9.806 55.870 29.212 1.00 34.48 ? 123 GLU M CB 1 ATOM 4314 C CG . GLU C 1 128 ? -9.567 54.483 29.909 1.00 47.54 ? 123 GLU M CG 1 ATOM 4315 C CD . GLU C 1 128 ? -10.605 53.560 30.595 1.00 51.09 ? 123 GLU M CD 1 ATOM 4316 O OE1 . GLU C 1 128 ? -11.659 53.234 30.034 1.00 48.11 ? 123 GLU M OE1 1 ATOM 4317 O OE2 . GLU C 1 128 ? -10.295 53.100 31.703 1.00 54.47 ? 123 GLU M OE2 1 ATOM 4318 N N . GLN C 1 129 ? -8.644 55.836 26.201 1.00 19.13 ? 124 GLN M N 1 ATOM 4319 C CA . GLN C 1 129 ? -8.501 55.033 25.015 1.00 19.06 ? 124 GLN M CA 1 ATOM 4320 C C . GLN C 1 129 ? -7.088 55.177 24.543 1.00 25.47 ? 124 GLN M C 1 ATOM 4321 O O . GLN C 1 129 ? -6.354 54.198 24.379 1.00 31.87 ? 124 GLN M O 1 ATOM 4322 C CB . GLN C 1 129 ? -9.405 55.489 23.892 1.00 18.83 ? 124 GLN M CB 1 ATOM 4323 C CG . GLN C 1 129 ? -9.328 54.398 22.838 1.00 16.80 ? 124 GLN M CG 1 ATOM 4324 C CD . GLN C 1 129 ? -10.285 54.505 21.673 1.00 15.23 ? 124 GLN M CD 1 ATOM 4325 O OE1 . GLN C 1 129 ? -10.226 53.659 20.794 1.00 11.27 ? 124 GLN M OE1 1 ATOM 4326 N NE2 . GLN C 1 129 ? -11.192 55.471 21.531 1.00 15.91 ? 124 GLN M NE2 1 ATOM 4327 N N . LEU C 1 130 ? -6.689 56.439 24.398 1.00 29.53 ? 125 LEU M N 1 ATOM 4328 C CA . LEU C 1 130 ? -5.381 56.752 23.844 1.00 27.86 ? 125 LEU M CA 1 ATOM 4329 C C . LEU C 1 130 ? -4.197 56.086 24.527 1.00 27.17 ? 125 LEU M C 1 ATOM 4330 O O . LEU C 1 130 ? -3.222 55.706 23.884 1.00 30.21 ? 125 LEU M O 1 ATOM 4331 C CB . LEU C 1 130 ? -5.227 58.236 23.863 1.00 20.46 ? 125 LEU M CB 1 ATOM 4332 C CG . LEU C 1 130 ? -5.914 58.893 22.731 1.00 15.60 ? 125 LEU M CG 1 ATOM 4333 C CD1 . LEU C 1 130 ? -5.685 60.364 22.855 1.00 17.26 ? 125 LEU M CD1 1 ATOM 4334 C CD2 . LEU C 1 130 ? -5.365 58.393 21.413 1.00 16.68 ? 125 LEU M CD2 1 ATOM 4335 N N . THR C 1 131 ? -4.339 55.841 25.812 1.00 20.47 ? 126 THR M N 1 ATOM 4336 C CA . THR C 1 131 ? -3.340 55.171 26.578 1.00 18.04 ? 126 THR M CA 1 ATOM 4337 C C . THR C 1 131 ? -3.244 53.731 26.149 1.00 18.58 ? 126 THR M C 1 ATOM 4338 O O . THR C 1 131 ? -2.116 53.225 26.090 1.00 19.64 ? 126 THR M O 1 ATOM 4339 C CB . THR C 1 131 ? -3.751 55.328 27.999 1.00 21.86 ? 126 THR M CB 1 ATOM 4340 O OG1 . THR C 1 131 ? -3.667 56.749 28.176 1.00 25.50 ? 126 THR M OG1 1 ATOM 4341 C CG2 . THR C 1 131 ? -2.972 54.477 28.991 1.00 17.85 ? 126 THR M CG2 1 ATOM 4342 N N . SER C 1 132 ? -4.347 53.037 25.834 1.00 15.56 ? 127 SER M N 1 ATOM 4343 C CA . SER C 1 132 ? -4.128 51.684 25.363 1.00 18.18 ? 127 SER M CA 1 ATOM 4344 C C . SER C 1 132 ? -3.679 51.706 23.894 1.00 13.31 ? 127 SER M C 1 ATOM 4345 O O . SER C 1 132 ? -3.445 50.668 23.270 1.00 12.72 ? 127 SER M O 1 ATOM 4346 C CB . SER C 1 132 ? -5.401 50.861 25.575 1.00 20.83 ? 127 SER M CB 1 ATOM 4347 O OG . SER C 1 132 ? -6.541 51.292 24.879 1.00 24.29 ? 127 SER M OG 1 ATOM 4348 N N . GLY C 1 133 ? -3.612 52.879 23.270 1.00 8.29 ? 128 GLY M N 1 ATOM 4349 C CA . GLY C 1 133 ? -2.935 52.987 21.998 1.00 12.34 ? 128 GLY M CA 1 ATOM 4350 C C . GLY C 1 133 ? -3.784 52.821 20.759 1.00 15.07 ? 128 GLY M C 1 ATOM 4351 O O . GLY C 1 133 ? -3.308 52.383 19.696 1.00 8.02 ? 128 GLY M O 1 ATOM 4352 N N . GLY C 1 134 ? -5.039 53.212 20.893 1.00 15.01 ? 129 GLY M N 1 ATOM 4353 C CA . GLY C 1 134 ? -5.940 53.196 19.762 1.00 13.06 ? 129 GLY M CA 1 ATOM 4354 C C . GLY C 1 134 ? -6.655 54.525 19.870 1.00 17.69 ? 129 GLY M C 1 ATOM 4355 O O . GLY C 1 134 ? -6.628 55.142 20.966 1.00 16.09 ? 129 GLY M O 1 ATOM 4356 N N . ALA C 1 135 ? -7.243 54.985 18.761 1.00 11.44 ? 130 ALA M N 1 ATOM 4357 C CA . ALA C 1 135 ? -8.033 56.189 18.813 1.00 11.16 ? 130 ALA M CA 1 ATOM 4358 C C . ALA C 1 135 ? -9.279 56.065 17.944 1.00 12.36 ? 130 ALA M C 1 ATOM 4359 O O . ALA C 1 135 ? -9.199 55.839 16.732 1.00 11.72 ? 130 ALA M O 1 ATOM 4360 C CB . ALA C 1 135 ? -7.173 57.346 18.356 1.00 12.35 ? 130 ALA M CB 1 ATOM 4361 N N . SER C 1 136 ? -10.452 56.167 18.576 1.00 9.37 ? 131 SER M N 1 ATOM 4362 C CA . SER C 1 136 ? -11.721 56.124 17.878 1.00 9.96 ? 131 SER M CA 1 ATOM 4363 C C . SER C 1 136 ? -12.504 57.424 18.001 1.00 17.73 ? 131 SER M C 1 ATOM 4364 O O . SER C 1 136 ? -12.919 57.844 19.093 1.00 23.88 ? 131 SER M O 1 ATOM 4365 C CB . SER C 1 136 ? -12.561 55.012 18.422 1.00 10.21 ? 131 SER M CB 1 ATOM 4366 O OG . SER C 1 136 ? -11.931 53.744 18.349 1.00 19.85 ? 131 SER M OG 1 ATOM 4367 N N . VAL C 1 137 ? -12.669 58.093 16.867 1.00 19.52 ? 132 VAL M N 1 ATOM 4368 C CA . VAL C 1 137 ? -13.408 59.346 16.748 1.00 21.02 ? 132 VAL M CA 1 ATOM 4369 C C . VAL C 1 137 ? -14.860 58.918 16.500 1.00 16.31 ? 132 VAL M C 1 ATOM 4370 O O . VAL C 1 137 ? -15.101 58.123 15.581 1.00 16.99 ? 132 VAL M O 1 ATOM 4371 C CB . VAL C 1 137 ? -12.833 60.190 15.536 1.00 22.79 ? 132 VAL M CB 1 ATOM 4372 C CG1 . VAL C 1 137 ? -13.503 61.548 15.623 1.00 21.56 ? 132 VAL M CG1 1 ATOM 4373 C CG2 . VAL C 1 137 ? -11.294 60.354 15.547 1.00 16.27 ? 132 VAL M CG2 1 ATOM 4374 N N . VAL C 1 138 ? -15.844 59.381 17.268 1.00 14.77 ? 133 VAL M N 1 ATOM 4375 C CA . VAL C 1 138 ? -17.226 58.920 17.140 1.00 11.79 ? 133 VAL M CA 1 ATOM 4376 C C . VAL C 1 138 ? -18.149 60.068 16.762 1.00 13.28 ? 133 VAL M C 1 ATOM 4377 O O . VAL C 1 138 ? -18.057 61.202 17.247 1.00 14.79 ? 133 VAL M O 1 ATOM 4378 C CB . VAL C 1 138 ? -17.738 58.281 18.479 1.00 10.93 ? 133 VAL M CB 1 ATOM 4379 C CG1 . VAL C 1 138 ? -19.074 57.622 18.204 1.00 15.47 ? 133 VAL M CG1 1 ATOM 4380 C CG2 . VAL C 1 138 ? -16.816 57.183 19.021 1.00 9.06 ? 133 VAL M CG2 1 ATOM 4381 N N . CYS C 1 139 ? -19.105 59.750 15.923 1.00 12.70 ? 134 CYS M N 1 ATOM 4382 C CA . CYS C 1 139 ? -20.024 60.730 15.460 1.00 13.00 ? 134 CYS M CA 1 ATOM 4383 C C . CYS C 1 139 ? -21.429 60.157 15.532 1.00 12.11 ? 134 CYS M C 1 ATOM 4384 O O . CYS C 1 139 ? -21.700 59.166 14.834 1.00 16.44 ? 134 CYS M O 1 ATOM 4385 C CB . CYS C 1 139 ? -19.594 61.046 14.062 1.00 20.77 ? 134 CYS M CB 1 ATOM 4386 S SG . CYS C 1 139 ? -20.442 62.488 13.381 1.00 31.93 ? 134 CYS M SG 1 ATOM 4387 N N . PHE C 1 140 ? -22.336 60.671 16.368 1.00 6.50 ? 135 PHE M N 1 ATOM 4388 C CA . PHE C 1 140 ? -23.703 60.179 16.381 1.00 9.87 ? 135 PHE M CA 1 ATOM 4389 C C . PHE C 1 140 ? -24.616 60.986 15.473 1.00 16.12 ? 135 PHE M C 1 ATOM 4390 O O . PHE C 1 140 ? -24.733 62.216 15.663 1.00 17.56 ? 135 PHE M O 1 ATOM 4391 C CB . PHE C 1 140 ? -24.340 60.253 17.748 1.00 9.33 ? 135 PHE M CB 1 ATOM 4392 C CG . PHE C 1 140 ? -23.683 59.413 18.808 1.00 8.64 ? 135 PHE M CG 1 ATOM 4393 C CD1 . PHE C 1 140 ? -23.544 58.058 18.626 1.00 3.87 ? 135 PHE M CD1 1 ATOM 4394 C CD2 . PHE C 1 140 ? -23.216 60.041 19.946 1.00 8.98 ? 135 PHE M CD2 1 ATOM 4395 C CE1 . PHE C 1 140 ? -22.922 57.340 19.618 1.00 11.54 ? 135 PHE M CE1 1 ATOM 4396 C CE2 . PHE C 1 140 ? -22.594 59.310 20.930 1.00 7.77 ? 135 PHE M CE2 1 ATOM 4397 C CZ . PHE C 1 140 ? -22.450 57.958 20.765 1.00 11.09 ? 135 PHE M CZ 1 ATOM 4398 N N . LEU C 1 141 ? -25.282 60.337 14.507 1.00 16.52 ? 136 LEU M N 1 ATOM 4399 C CA . LEU C 1 141 ? -26.235 61.041 13.639 1.00 15.98 ? 136 LEU M CA 1 ATOM 4400 C C . LEU C 1 141 ? -27.625 60.708 14.215 1.00 12.77 ? 136 LEU M C 1 ATOM 4401 O O . LEU C 1 141 ? -28.387 59.848 13.764 1.00 8.62 ? 136 LEU M O 1 ATOM 4402 C CB . LEU C 1 141 ? -26.116 60.546 12.178 1.00 17.93 ? 136 LEU M CB 1 ATOM 4403 C CG . LEU C 1 141 ? -24.918 60.732 11.186 1.00 19.37 ? 136 LEU M CG 1 ATOM 4404 C CD1 . LEU C 1 141 ? -24.657 62.186 11.002 1.00 19.62 ? 136 LEU M CD1 1 ATOM 4405 C CD2 . LEU C 1 141 ? -23.627 60.153 11.706 1.00 23.20 ? 136 LEU M CD2 1 ATOM 4406 N N . ASN C 1 142 ? -27.989 61.413 15.268 1.00 12.02 ? 137 ASN M N 1 ATOM 4407 C CA . ASN C 1 142 ? -29.189 61.089 15.992 1.00 14.73 ? 137 ASN M CA 1 ATOM 4408 C C . ASN C 1 142 ? -30.436 61.739 15.477 1.00 14.31 ? 137 ASN M C 1 ATOM 4409 O O . ASN C 1 142 ? -30.432 62.899 15.111 1.00 4.93 ? 137 ASN M O 1 ATOM 4410 C CB . ASN C 1 142 ? -29.025 61.453 17.483 1.00 20.06 ? 137 ASN M CB 1 ATOM 4411 C CG . ASN C 1 142 ? -28.407 60.355 18.365 1.00 22.35 ? 137 ASN M CG 1 ATOM 4412 O OD1 . ASN C 1 142 ? -28.525 59.163 18.075 1.00 26.23 ? 137 ASN M OD1 1 ATOM 4413 N ND2 . ASN C 1 142 ? -27.804 60.636 19.515 1.00 20.75 ? 137 ASN M ND2 1 ATOM 4414 N N . ASN C 1 143 ? -31.483 60.909 15.546 1.00 23.40 ? 138 ASN M N 1 ATOM 4415 C CA . ASN C 1 143 ? -32.927 61.121 15.265 1.00 22.62 ? 138 ASN M CA 1 ATOM 4416 C C . ASN C 1 143 ? -33.344 61.745 13.958 1.00 23.53 ? 138 ASN M C 1 ATOM 4417 O O . ASN C 1 143 ? -33.804 62.886 13.923 1.00 35.17 ? 138 ASN M O 1 ATOM 4418 C CB . ASN C 1 143 ? -33.604 61.964 16.362 1.00 21.56 ? 138 ASN M CB 1 ATOM 4419 C CG . ASN C 1 143 ? -33.727 61.364 17.737 1.00 26.28 ? 138 ASN M CG 1 ATOM 4420 O OD1 . ASN C 1 143 ? -34.425 60.374 17.978 1.00 31.41 ? 138 ASN M OD1 1 ATOM 4421 N ND2 . ASN C 1 143 ? -32.991 61.941 18.688 1.00 31.11 ? 138 ASN M ND2 1 ATOM 4422 N N . PHE C 1 144 ? -33.286 61.040 12.849 1.00 24.28 ? 139 PHE M N 1 ATOM 4423 C CA . PHE C 1 144 ? -33.627 61.649 11.557 1.00 24.32 ? 139 PHE M CA 1 ATOM 4424 C C . PHE C 1 144 ? -34.612 60.820 10.733 1.00 25.49 ? 139 PHE M C 1 ATOM 4425 O O . PHE C 1 144 ? -35.110 59.808 11.206 1.00 31.82 ? 139 PHE M O 1 ATOM 4426 C CB . PHE C 1 144 ? -32.332 61.886 10.755 1.00 19.02 ? 139 PHE M CB 1 ATOM 4427 C CG . PHE C 1 144 ? -31.475 60.655 10.524 1.00 16.25 ? 139 PHE M CG 1 ATOM 4428 C CD1 . PHE C 1 144 ? -31.720 59.832 9.439 1.00 13.98 ? 139 PHE M CD1 1 ATOM 4429 C CD2 . PHE C 1 144 ? -30.435 60.365 11.392 1.00 17.66 ? 139 PHE M CD2 1 ATOM 4430 C CE1 . PHE C 1 144 ? -30.916 58.725 9.227 1.00 14.01 ? 139 PHE M CE1 1 ATOM 4431 C CE2 . PHE C 1 144 ? -29.642 59.249 11.160 1.00 16.15 ? 139 PHE M CE2 1 ATOM 4432 C CZ . PHE C 1 144 ? -29.874 58.427 10.080 1.00 9.14 ? 139 PHE M CZ 1 ATOM 4433 N N . TYR C 1 145 ? -34.939 61.172 9.506 1.00 30.44 ? 140 TYR M N 1 ATOM 4434 C CA . TYR C 1 145 ? -35.859 60.413 8.666 1.00 29.10 ? 140 TYR M CA 1 ATOM 4435 C C . TYR C 1 145 ? -35.689 61.070 7.311 1.00 28.93 ? 140 TYR M C 1 ATOM 4436 O O . TYR C 1 145 ? -35.528 62.306 7.227 1.00 25.10 ? 140 TYR M O 1 ATOM 4437 C CB . TYR C 1 145 ? -37.336 60.560 9.107 1.00 26.73 ? 140 TYR M CB 1 ATOM 4438 C CG . TYR C 1 145 ? -38.248 59.753 8.210 1.00 19.33 ? 140 TYR M CG 1 ATOM 4439 C CD1 . TYR C 1 145 ? -38.483 58.427 8.461 1.00 23.47 ? 140 TYR M CD1 1 ATOM 4440 C CD2 . TYR C 1 145 ? -38.779 60.331 7.095 1.00 17.64 ? 140 TYR M CD2 1 ATOM 4441 C CE1 . TYR C 1 145 ? -39.246 57.685 7.580 1.00 21.52 ? 140 TYR M CE1 1 ATOM 4442 C CE2 . TYR C 1 145 ? -39.533 59.600 6.209 1.00 20.35 ? 140 TYR M CE2 1 ATOM 4443 C CZ . TYR C 1 145 ? -39.754 58.279 6.451 1.00 18.45 ? 140 TYR M CZ 1 ATOM 4444 O OH . TYR C 1 145 ? -40.418 57.541 5.500 1.00 19.81 ? 140 TYR M OH 1 ATOM 4445 N N . PRO C 1 146 ? -35.686 60.333 6.208 1.00 32.58 ? 141 PRO M N 1 ATOM 4446 C CA . PRO C 1 146 ? -35.578 58.878 6.113 1.00 36.74 ? 141 PRO M CA 1 ATOM 4447 C C . PRO C 1 146 ? -34.261 58.312 6.600 1.00 36.12 ? 141 PRO M C 1 ATOM 4448 O O . PRO C 1 146 ? -33.452 59.010 7.218 1.00 33.11 ? 141 PRO M O 1 ATOM 4449 C CB . PRO C 1 146 ? -35.818 58.550 4.642 1.00 37.82 ? 141 PRO M CB 1 ATOM 4450 C CG . PRO C 1 146 ? -36.650 59.718 4.186 1.00 38.72 ? 141 PRO M CG 1 ATOM 4451 C CD . PRO C 1 146 ? -35.978 60.888 4.894 1.00 34.94 ? 141 PRO M CD 1 ATOM 4452 N N . LYS C 1 147 ? -34.146 57.030 6.251 1.00 33.49 ? 142 LYS M N 1 ATOM 4453 C CA . LYS C 1 147 ? -33.037 56.187 6.605 1.00 34.68 ? 142 LYS M CA 1 ATOM 4454 C C . LYS C 1 147 ? -31.758 56.711 5.970 1.00 37.51 ? 142 LYS M C 1 ATOM 4455 O O . LYS C 1 147 ? -30.722 56.849 6.612 1.00 32.79 ? 142 LYS M O 1 ATOM 4456 C CB . LYS C 1 147 ? -33.420 54.786 6.124 1.00 34.15 ? 142 LYS M CB 1 ATOM 4457 C CG . LYS C 1 147 ? -32.410 53.678 6.277 1.00 37.68 ? 142 LYS M CG 1 ATOM 4458 C CD . LYS C 1 147 ? -32.583 52.863 7.536 1.00 43.07 ? 142 LYS M CD 1 ATOM 4459 C CE . LYS C 1 147 ? -31.597 51.684 7.428 1.00 50.24 ? 142 LYS M CE 1 ATOM 4460 N NZ . LYS C 1 147 ? -31.665 50.764 8.558 1.00 52.98 ? 142 LYS M NZ 1 ATOM 4461 N N . ASP C 1 148 ? -31.861 57.001 4.672 1.00 43.64 ? 143 ASP M N 1 ATOM 4462 C CA . ASP C 1 148 ? -30.728 57.405 3.861 1.00 43.10 ? 143 ASP M CA 1 ATOM 4463 C C . ASP C 1 148 ? -30.055 58.637 4.422 1.00 39.76 ? 143 ASP M C 1 ATOM 4464 O O . ASP C 1 148 ? -30.671 59.706 4.564 1.00 42.99 ? 143 ASP M O 1 ATOM 4465 C CB . ASP C 1 148 ? -31.182 57.704 2.431 1.00 51.88 ? 143 ASP M CB 1 ATOM 4466 C CG . ASP C 1 148 ? -30.095 57.587 1.358 1.00 62.42 ? 143 ASP M CG 1 ATOM 4467 O OD1 . ASP C 1 148 ? -29.025 58.195 1.473 1.00 65.12 ? 143 ASP M OD1 1 ATOM 4468 O OD2 . ASP C 1 148 ? -30.334 56.874 0.381 1.00 67.90 ? 143 ASP M OD2 1 ATOM 4469 N N . ILE C 1 149 ? -28.786 58.450 4.742 1.00 30.71 ? 144 ILE M N 1 ATOM 4470 C CA . ILE C 1 149 ? -27.934 59.523 5.179 1.00 22.29 ? 144 ILE M CA 1 ATOM 4471 C C . ILE C 1 149 ? -26.552 59.117 4.683 1.00 26.92 ? 144 ILE M C 1 ATOM 4472 O O . ILE C 1 149 ? -26.320 57.941 4.369 1.00 27.15 ? 144 ILE M O 1 ATOM 4473 C CB . ILE C 1 149 ? -28.045 59.646 6.719 1.00 13.24 ? 144 ILE M CB 1 ATOM 4474 C CG1 . ILE C 1 149 ? -27.346 60.878 7.174 1.00 11.20 ? 144 ILE M CG1 1 ATOM 4475 C CG2 . ILE C 1 149 ? -27.401 58.472 7.405 1.00 18.61 ? 144 ILE M CG2 1 ATOM 4476 C CD1 . ILE C 1 149 ? -27.744 61.200 8.595 1.00 13.50 ? 144 ILE M CD1 1 ATOM 4477 N N . ASN C 1 150 ? -25.629 60.061 4.497 1.00 36.28 ? 145 ASN M N 1 ATOM 4478 C CA . ASN C 1 150 ? -24.281 59.731 4.081 1.00 41.43 ? 145 ASN M CA 1 ATOM 4479 C C . ASN C 1 150 ? -23.272 60.517 4.888 1.00 42.88 ? 145 ASN M C 1 ATOM 4480 O O . ASN C 1 150 ? -23.389 61.746 5.037 1.00 41.48 ? 145 ASN M O 1 ATOM 4481 C CB . ASN C 1 150 ? -24.107 60.011 2.597 1.00 43.42 ? 145 ASN M CB 1 ATOM 4482 C CG . ASN C 1 150 ? -23.754 58.690 1.920 1.00 48.38 ? 145 ASN M CG 1 ATOM 4483 O OD1 . ASN C 1 150 ? -22.734 58.547 1.257 1.00 50.94 ? 145 ASN M OD1 1 ATOM 4484 N ND2 . ASN C 1 150 ? -24.541 57.635 2.076 1.00 51.21 ? 145 ASN M ND2 1 ATOM 4485 N N . VAL C 1 151 ? -22.381 59.704 5.487 1.00 39.04 ? 146 VAL M N 1 ATOM 4486 C CA . VAL C 1 151 ? -21.345 60.143 6.416 1.00 33.72 ? 146 VAL M CA 1 ATOM 4487 C C . VAL C 1 151 ? -19.949 60.103 5.789 1.00 35.16 ? 146 VAL M C 1 ATOM 4488 O O . VAL C 1 151 ? -19.466 59.061 5.338 1.00 35.89 ? 146 VAL M O 1 ATOM 4489 C CB . VAL C 1 151 ? -21.405 59.242 7.682 1.00 28.86 ? 146 VAL M CB 1 ATOM 4490 C CG1 . VAL C 1 151 ? -20.248 59.519 8.646 1.00 21.31 ? 146 VAL M CG1 1 ATOM 4491 C CG2 . VAL C 1 151 ? -22.741 59.495 8.359 1.00 26.43 ? 146 VAL M CG2 1 ATOM 4492 N N . LYS C 1 152 ? -19.285 61.244 5.696 1.00 31.88 ? 147 LYS M N 1 ATOM 4493 C CA . LYS C 1 152 ? -17.944 61.249 5.200 1.00 30.23 ? 147 LYS M CA 1 ATOM 4494 C C . LYS C 1 152 ? -17.116 61.701 6.370 1.00 28.17 ? 147 LYS M C 1 ATOM 4495 O O . LYS C 1 152 ? -17.505 62.597 7.126 1.00 33.32 ? 147 LYS M O 1 ATOM 4496 C CB . LYS C 1 152 ? -17.805 62.210 4.034 1.00 33.88 ? 147 LYS M CB 1 ATOM 4497 C CG . LYS C 1 152 ? -18.653 61.664 2.895 1.00 43.67 ? 147 LYS M CG 1 ATOM 4498 C CD . LYS C 1 152 ? -18.048 61.820 1.512 1.00 48.08 ? 147 LYS M CD 1 ATOM 4499 C CE . LYS C 1 152 ? -18.001 63.256 1.026 1.00 51.97 ? 147 LYS M CE 1 ATOM 4500 N NZ . LYS C 1 152 ? -17.284 63.308 -0.234 1.00 55.00 ? 147 LYS M NZ 1 ATOM 4501 N N . TRP C 1 153 ? -16.016 60.990 6.560 1.00 26.91 ? 148 TRP M N 1 ATOM 4502 C CA . TRP C 1 153 ? -15.015 61.331 7.553 1.00 26.20 ? 148 TRP M CA 1 ATOM 4503 C C . TRP C 1 153 ? -13.942 62.099 6.802 1.00 24.76 ? 148 TRP M C 1 ATOM 4504 O O . TRP C 1 153 ? -13.554 61.677 5.710 1.00 26.48 ? 148 TRP M O 1 ATOM 4505 C CB . TRP C 1 153 ? -14.406 60.049 8.205 1.00 22.48 ? 148 TRP M CB 1 ATOM 4506 C CG . TRP C 1 153 ? -15.203 59.669 9.440 1.00 17.20 ? 148 TRP M CG 1 ATOM 4507 C CD1 . TRP C 1 153 ? -16.107 58.653 9.411 1.00 16.78 ? 148 TRP M CD1 1 ATOM 4508 C CD2 . TRP C 1 153 ? -15.190 60.321 10.651 1.00 16.18 ? 148 TRP M CD2 1 ATOM 4509 N NE1 . TRP C 1 153 ? -16.688 58.665 10.589 1.00 14.33 ? 148 TRP M NE1 1 ATOM 4510 C CE2 . TRP C 1 153 ? -16.167 59.638 11.348 1.00 13.68 ? 148 TRP M CE2 1 ATOM 4511 C CE3 . TRP C 1 153 ? -14.517 61.362 11.242 1.00 13.12 ? 148 TRP M CE3 1 ATOM 4512 C CZ2 . TRP C 1 153 ? -16.485 59.983 12.635 1.00 16.50 ? 148 TRP M CZ2 1 ATOM 4513 C CZ3 . TRP C 1 153 ? -14.837 61.705 12.535 1.00 13.85 ? 148 TRP M CZ3 1 ATOM 4514 C CH2 . TRP C 1 153 ? -15.811 61.024 13.229 1.00 15.76 ? 148 TRP M CH2 1 ATOM 4515 N N . LYS C 1 154 ? -13.519 63.240 7.327 1.00 26.56 ? 149 LYS M N 1 ATOM 4516 C CA . LYS C 1 154 ? -12.435 64.038 6.775 1.00 22.89 ? 149 LYS M CA 1 ATOM 4517 C C . LYS C 1 154 ? -11.387 64.251 7.874 1.00 22.90 ? 149 LYS M C 1 ATOM 4518 O O . LYS C 1 154 ? -11.663 64.615 9.032 1.00 22.60 ? 149 LYS M O 1 ATOM 4519 C CB . LYS C 1 154 ? -12.998 65.378 6.269 1.00 15.82 ? 149 LYS M CB 1 ATOM 4520 C CG . LYS C 1 154 ? -13.173 65.348 4.746 1.00 17.42 ? 149 LYS M CG 1 ATOM 4521 C CD . LYS C 1 154 ? -14.550 65.670 4.171 1.00 14.46 ? 149 LYS M CD 1 ATOM 4522 C CE . LYS C 1 154 ? -14.572 67.020 3.473 1.00 18.98 ? 149 LYS M CE 1 ATOM 4523 N NZ . LYS C 1 154 ? -14.431 68.114 4.429 1.00 19.36 ? 149 LYS M NZ 1 ATOM 4524 N N . ILE C 1 155 ? -10.153 63.919 7.557 1.00 20.70 ? 150 ILE M N 1 ATOM 4525 C CA . ILE C 1 155 ? -9.038 64.125 8.455 1.00 20.39 ? 150 ILE M CA 1 ATOM 4526 C C . ILE C 1 155 ? -8.087 65.041 7.678 1.00 18.33 ? 150 ILE M C 1 ATOM 4527 O O . ILE C 1 155 ? -7.588 64.659 6.616 1.00 12.86 ? 150 ILE M O 1 ATOM 4528 C CB . ILE C 1 155 ? -8.320 62.792 8.786 1.00 23.83 ? 150 ILE M CB 1 ATOM 4529 C CG1 . ILE C 1 155 ? -9.227 61.749 9.348 1.00 25.73 ? 150 ILE M CG1 1 ATOM 4530 C CG2 . ILE C 1 155 ? -7.303 63.046 9.842 1.00 25.02 ? 150 ILE M CG2 1 ATOM 4531 C CD1 . ILE C 1 155 ? -9.782 60.934 8.185 1.00 32.09 ? 150 ILE M CD1 1 ATOM 4532 N N . ASP C 1 156 ? -7.848 66.252 8.188 1.00 14.57 ? 151 ASP M N 1 ATOM 4533 C CA . ASP C 1 156 ? -6.931 67.223 7.599 1.00 20.73 ? 151 ASP M CA 1 ATOM 4534 C C . ASP C 1 156 ? -7.016 67.447 6.109 1.00 26.87 ? 151 ASP M C 1 ATOM 4535 O O . ASP C 1 156 ? -6.243 67.011 5.244 1.00 27.37 ? 151 ASP M O 1 ATOM 4536 C CB . ASP C 1 156 ? -5.480 66.886 7.921 1.00 20.05 ? 151 ASP M CB 1 ATOM 4537 C CG . ASP C 1 156 ? -5.010 67.311 9.306 1.00 28.73 ? 151 ASP M CG 1 ATOM 4538 O OD1 . ASP C 1 156 ? -5.657 68.104 9.999 1.00 29.53 ? 151 ASP M OD1 1 ATOM 4539 O OD2 . ASP C 1 156 ? -3.946 66.841 9.693 1.00 31.58 ? 151 ASP M OD2 1 ATOM 4540 N N . GLY C 1 157 ? -8.083 68.180 5.890 1.00 33.56 ? 152 GLY M N 1 ATOM 4541 C CA . GLY C 1 157 ? -8.370 68.588 4.549 1.00 49.52 ? 152 GLY M CA 1 ATOM 4542 C C . GLY C 1 157 ? -9.336 67.587 3.970 1.00 56.28 ? 152 GLY M C 1 ATOM 4543 O O . GLY C 1 157 ? -9.896 66.784 4.715 1.00 57.00 ? 152 GLY M O 1 ATOM 4544 N N . SER C 1 158 ? -9.547 67.560 2.657 1.00 62.43 ? 153 SER M N 1 ATOM 4545 C CA . SER C 1 158 ? -10.562 66.699 2.076 1.00 68.84 ? 153 SER M CA 1 ATOM 4546 C C . SER C 1 158 ? -10.032 65.274 1.989 1.00 69.70 ? 153 SER M C 1 ATOM 4547 O O . SER C 1 158 ? -10.251 64.528 1.020 1.00 74.94 ? 153 SER M O 1 ATOM 4548 C CB . SER C 1 158 ? -10.945 67.262 0.680 1.00 73.28 ? 153 SER M CB 1 ATOM 4549 O OG . SER C 1 158 ? -12.251 66.929 0.192 1.00 75.33 ? 153 SER M OG 1 ATOM 4550 N N . GLU C 1 159 ? -9.320 64.845 3.017 1.00 62.17 ? 154 GLU M N 1 ATOM 4551 C CA . GLU C 1 159 ? -8.817 63.524 2.967 1.00 63.52 ? 154 GLU M CA 1 ATOM 4552 C C . GLU C 1 159 ? -9.842 62.847 3.829 1.00 55.84 ? 154 GLU M C 1 ATOM 4553 O O . GLU C 1 159 ? -10.233 63.278 4.906 1.00 46.76 ? 154 GLU M O 1 ATOM 4554 C CB . GLU C 1 159 ? -7.379 63.550 3.492 1.00 70.34 ? 154 GLU M CB 1 ATOM 4555 C CG . GLU C 1 159 ? -6.392 64.328 2.554 1.00 74.90 ? 154 GLU M CG 1 ATOM 4556 C CD . GLU C 1 159 ? -6.197 63.870 1.088 1.00 75.08 ? 154 GLU M CD 1 ATOM 4557 O OE1 . GLU C 1 159 ? -7.148 63.921 0.299 1.00 72.67 ? 154 GLU M OE1 1 ATOM 4558 O OE2 . GLU C 1 159 ? -5.075 63.491 0.723 1.00 75.91 ? 154 GLU M OE2 1 ATOM 4559 N N . ARG C 1 160 ? -10.494 62.017 3.034 1.00 55.43 ? 155 ARG M N 1 ATOM 4560 C CA . ARG C 1 160 ? -11.534 61.130 3.513 1.00 58.76 ? 155 ARG M CA 1 ATOM 4561 C C . ARG C 1 160 ? -10.855 59.900 4.145 1.00 58.38 ? 155 ARG M C 1 ATOM 4562 O O . ARG C 1 160 ? -9.610 59.863 4.124 1.00 58.62 ? 155 ARG M O 1 ATOM 4563 C CB . ARG C 1 160 ? -12.423 60.706 2.331 1.00 59.43 ? 155 ARG M CB 1 ATOM 4564 C CG . ARG C 1 160 ? -12.929 61.786 1.363 1.00 59.10 ? 155 ARG M CG 1 ATOM 4565 C CD . ARG C 1 160 ? -14.388 61.577 0.942 1.00 59.31 ? 155 ARG M CD 1 ATOM 4566 N NE . ARG C 1 160 ? -14.681 60.238 0.451 1.00 62.88 ? 155 ARG M NE 1 ATOM 4567 C CZ . ARG C 1 160 ? -15.383 59.330 1.151 1.00 67.43 ? 155 ARG M CZ 1 ATOM 4568 N NH1 . ARG C 1 160 ? -15.854 59.570 2.378 1.00 68.65 ? 155 ARG M NH1 1 ATOM 4569 N NH2 . ARG C 1 160 ? -15.608 58.129 0.620 1.00 70.07 ? 155 ARG M NH2 1 ATOM 4570 N N . GLN C 1 161 ? -11.542 58.893 4.730 1.00 52.38 ? 156 GLN M N 1 ATOM 4571 C CA . GLN C 1 161 ? -10.826 57.700 5.144 1.00 50.35 ? 156 GLN M CA 1 ATOM 4572 C C . GLN C 1 161 ? -11.463 56.323 4.817 1.00 55.10 ? 156 GLN M C 1 ATOM 4573 O O . GLN C 1 161 ? -12.522 56.264 4.172 1.00 52.48 ? 156 GLN M O 1 ATOM 4574 C CB . GLN C 1 161 ? -10.541 57.892 6.625 1.00 43.37 ? 156 GLN M CB 1 ATOM 4575 C CG . GLN C 1 161 ? -9.015 58.020 6.865 1.00 42.10 ? 156 GLN M CG 1 ATOM 4576 C CD . GLN C 1 161 ? -8.221 56.718 6.921 1.00 42.74 ? 156 GLN M CD 1 ATOM 4577 O OE1 . GLN C 1 161 ? -8.262 55.919 5.998 1.00 44.06 ? 156 GLN M OE1 1 ATOM 4578 N NE2 . GLN C 1 161 ? -7.467 56.379 7.952 1.00 40.36 ? 156 GLN M NE2 1 ATOM 4579 N N . ASN C 1 162 ? -10.809 55.222 5.274 1.00 56.08 ? 157 ASN M N 1 ATOM 4580 C CA . ASN C 1 162 ? -11.090 53.793 5.059 1.00 51.93 ? 157 ASN M CA 1 ATOM 4581 C C . ASN C 1 162 ? -10.941 53.045 6.409 1.00 45.57 ? 157 ASN M C 1 ATOM 4582 O O . ASN C 1 162 ? -9.830 52.870 6.889 1.00 39.87 ? 157 ASN M O 1 ATOM 4583 C CB . ASN C 1 162 ? -10.063 53.328 4.040 1.00 59.63 ? 157 ASN M CB 1 ATOM 4584 C CG . ASN C 1 162 ? -10.401 52.101 3.214 1.00 63.90 ? 157 ASN M CG 1 ATOM 4585 O OD1 . ASN C 1 162 ? -10.590 50.980 3.704 1.00 64.17 ? 157 ASN M OD1 1 ATOM 4586 N ND2 . ASN C 1 162 ? -10.470 52.317 1.898 1.00 63.52 ? 157 ASN M ND2 1 ATOM 4587 N N . GLY C 1 163 ? -11.976 52.547 7.092 1.00 43.95 ? 158 GLY M N 1 ATOM 4588 C CA . GLY C 1 163 ? -11.871 52.039 8.483 1.00 39.31 ? 158 GLY M CA 1 ATOM 4589 C C . GLY C 1 163 ? -12.924 52.700 9.441 1.00 35.07 ? 158 GLY M C 1 ATOM 4590 O O . GLY C 1 163 ? -12.701 53.224 10.556 1.00 25.96 ? 158 GLY M O 1 ATOM 4591 N N . VAL C 1 164 ? -14.177 52.626 8.988 1.00 30.08 ? 159 VAL M N 1 ATOM 4592 C CA . VAL C 1 164 ? -15.280 53.325 9.606 1.00 25.08 ? 159 VAL M CA 1 ATOM 4593 C C . VAL C 1 164 ? -16.329 52.252 9.837 1.00 25.47 ? 159 VAL M C 1 ATOM 4594 O O . VAL C 1 164 ? -16.588 51.412 8.968 1.00 28.69 ? 159 VAL M O 1 ATOM 4595 C CB . VAL C 1 164 ? -15.699 54.446 8.596 1.00 21.66 ? 159 VAL M CB 1 ATOM 4596 C CG1 . VAL C 1 164 ? -17.017 55.155 8.893 1.00 16.58 ? 159 VAL M CG1 1 ATOM 4597 C CG2 . VAL C 1 164 ? -14.632 55.514 8.711 1.00 21.88 ? 159 VAL M CG2 1 ATOM 4598 N N . LEU C 1 165 ? -16.924 52.299 11.019 1.00 25.73 ? 160 LEU M N 1 ATOM 4599 C CA . LEU C 1 165 ? -17.930 51.358 11.477 1.00 26.35 ? 160 LEU M CA 1 ATOM 4600 C C . LEU C 1 165 ? -19.213 52.146 11.576 1.00 28.57 ? 160 LEU M C 1 ATOM 4601 O O . LEU C 1 165 ? -19.182 53.169 12.286 1.00 29.52 ? 160 LEU M O 1 ATOM 4602 C CB . LEU C 1 165 ? -17.548 50.849 12.853 1.00 24.45 ? 160 LEU M CB 1 ATOM 4603 C CG . LEU C 1 165 ? -17.500 49.364 13.096 1.00 17.85 ? 160 LEU M CG 1 ATOM 4604 C CD1 . LEU C 1 165 ? -16.583 48.704 12.085 1.00 17.16 ? 160 LEU M CD1 1 ATOM 4605 C CD2 . LEU C 1 165 ? -17.064 49.136 14.529 1.00 15.22 ? 160 LEU M CD2 1 ATOM 4606 N N . ASN C 1 166 ? -20.296 51.711 10.904 1.00 25.55 ? 161 ASN M N 1 ATOM 4607 C CA . ASN C 1 166 ? -21.554 52.462 10.944 1.00 21.87 ? 161 ASN M CA 1 ATOM 4608 C C . ASN C 1 166 ? -22.656 51.556 11.411 1.00 19.24 ? 161 ASN M C 1 ATOM 4609 O O . ASN C 1 166 ? -22.764 50.497 10.783 1.00 25.48 ? 161 ASN M O 1 ATOM 4610 C CB . ASN C 1 166 ? -22.085 52.947 9.610 1.00 18.80 ? 161 ASN M CB 1 ATOM 4611 C CG . ASN C 1 166 ? -21.201 53.893 8.847 1.00 23.29 ? 161 ASN M CG 1 ATOM 4612 O OD1 . ASN C 1 166 ? -20.787 54.961 9.290 1.00 19.34 ? 161 ASN M OD1 1 ATOM 4613 N ND2 . ASN C 1 166 ? -20.883 53.474 7.635 1.00 27.40 ? 161 ASN M ND2 1 ATOM 4614 N N . SER C 1 167 ? -23.469 51.861 12.429 1.00 14.03 ? 162 SER M N 1 ATOM 4615 C CA . SER C 1 167 ? -24.641 51.041 12.716 1.00 21.64 ? 162 SER M CA 1 ATOM 4616 C C . SER C 1 167 ? -25.857 51.919 12.862 1.00 20.90 ? 162 SER M C 1 ATOM 4617 O O . SER C 1 167 ? -25.752 53.043 13.364 1.00 23.08 ? 162 SER M O 1 ATOM 4618 C CB . SER C 1 167 ? -24.491 50.252 13.994 1.00 26.42 ? 162 SER M CB 1 ATOM 4619 O OG . SER C 1 167 ? -23.343 49.429 13.821 1.00 42.02 ? 162 SER M OG 1 ATOM 4620 N N . TRP C 1 168 ? -26.994 51.476 12.341 1.00 19.03 ? 163 TRP M N 1 ATOM 4621 C CA . TRP C 1 168 ? -28.217 52.229 12.494 1.00 19.61 ? 163 TRP M CA 1 ATOM 4622 C C . TRP C 1 168 ? -29.110 51.496 13.457 1.00 16.92 ? 163 TRP M C 1 ATOM 4623 O O . TRP C 1 168 ? -29.070 50.263 13.540 1.00 19.87 ? 163 TRP M O 1 ATOM 4624 C CB . TRP C 1 168 ? -29.045 52.326 11.249 1.00 26.21 ? 163 TRP M CB 1 ATOM 4625 C CG . TRP C 1 168 ? -28.593 53.233 10.129 1.00 31.54 ? 163 TRP M CG 1 ATOM 4626 C CD1 . TRP C 1 168 ? -29.265 54.390 9.852 1.00 32.40 ? 163 TRP M CD1 1 ATOM 4627 C CD2 . TRP C 1 168 ? -27.601 52.966 9.240 1.00 30.64 ? 163 TRP M CD2 1 ATOM 4628 N NE1 . TRP C 1 168 ? -28.717 54.840 8.758 1.00 33.02 ? 163 TRP M NE1 1 ATOM 4629 C CE2 . TRP C 1 168 ? -27.734 54.025 8.362 1.00 31.83 ? 163 TRP M CE2 1 ATOM 4630 C CE3 . TRP C 1 168 ? -26.661 51.982 9.069 1.00 29.65 ? 163 TRP M CE3 1 ATOM 4631 C CZ2 . TRP C 1 168 ? -26.914 54.138 7.274 1.00 32.68 ? 163 TRP M CZ2 1 ATOM 4632 C CZ3 . TRP C 1 168 ? -25.835 52.090 7.976 1.00 31.57 ? 163 TRP M CZ3 1 ATOM 4633 C CH2 . TRP C 1 168 ? -25.960 53.154 7.103 1.00 32.80 ? 163 TRP M CH2 1 ATOM 4634 N N . THR C 1 169 ? -29.908 52.244 14.187 1.00 11.24 ? 164 THR M N 1 ATOM 4635 C CA . THR C 1 169 ? -30.972 51.649 14.953 1.00 12.43 ? 164 THR M CA 1 ATOM 4636 C C . THR C 1 169 ? -32.088 51.285 13.943 1.00 20.26 ? 164 THR M C 1 ATOM 4637 O O . THR C 1 169 ? -32.096 51.816 12.823 1.00 23.01 ? 164 THR M O 1 ATOM 4638 C CB . THR C 1 169 ? -31.357 52.700 15.974 1.00 12.21 ? 164 THR M CB 1 ATOM 4639 O OG1 . THR C 1 169 ? -31.423 53.943 15.291 1.00 22.43 ? 164 THR M OG1 1 ATOM 4640 C CG2 . THR C 1 169 ? -30.330 52.882 17.062 1.00 16.26 ? 164 THR M CG2 1 ATOM 4641 N N . ASP C 1 170 ? -33.029 50.364 14.234 1.00 26.28 ? 165 ASP M N 1 ATOM 4642 C CA . ASP C 1 170 ? -34.157 50.038 13.338 1.00 24.55 ? 165 ASP M CA 1 ATOM 4643 C C . ASP C 1 170 ? -35.146 51.155 13.578 1.00 19.11 ? 165 ASP M C 1 ATOM 4644 O O . ASP C 1 170 ? -34.895 51.933 14.494 1.00 15.02 ? 165 ASP M O 1 ATOM 4645 C CB . ASP C 1 170 ? -34.918 48.769 13.687 1.00 30.98 ? 165 ASP M CB 1 ATOM 4646 C CG . ASP C 1 170 ? -34.112 47.575 14.161 1.00 39.89 ? 165 ASP M CG 1 ATOM 4647 O OD1 . ASP C 1 170 ? -33.416 47.662 15.179 1.00 44.42 ? 165 ASP M OD1 1 ATOM 4648 O OD2 . ASP C 1 170 ? -34.205 46.537 13.517 1.00 43.49 ? 165 ASP M OD2 1 ATOM 4649 N N . GLN C 1 171 ? -36.284 51.277 12.887 1.00 19.06 ? 166 GLN M N 1 ATOM 4650 C CA . GLN C 1 171 ? -37.123 52.449 13.072 1.00 14.12 ? 166 GLN M CA 1 ATOM 4651 C C . GLN C 1 171 ? -37.608 52.577 14.496 1.00 12.20 ? 166 GLN M C 1 ATOM 4652 O O . GLN C 1 171 ? -38.015 51.603 15.127 1.00 16.10 ? 166 GLN M O 1 ATOM 4653 C CB . GLN C 1 171 ? -38.266 52.359 12.115 1.00 9.79 ? 166 GLN M CB 1 ATOM 4654 C CG . GLN C 1 171 ? -39.065 53.640 12.103 1.00 6.64 ? 166 GLN M CG 1 ATOM 4655 C CD . GLN C 1 171 ? -39.949 53.683 10.883 1.00 10.37 ? 166 GLN M CD 1 ATOM 4656 O OE1 . GLN C 1 171 ? -40.245 52.672 10.255 1.00 15.66 ? 166 GLN M OE1 1 ATOM 4657 N NE2 . GLN C 1 171 ? -40.377 54.840 10.436 1.00 12.20 ? 166 GLN M NE2 1 ATOM 4658 N N . ASP C 1 172 ? -37.440 53.777 15.026 1.00 12.25 ? 167 ASP M N 1 ATOM 4659 C CA . ASP C 1 172 ? -37.827 54.059 16.385 1.00 22.46 ? 167 ASP M CA 1 ATOM 4660 C C . ASP C 1 172 ? -39.324 54.061 16.453 1.00 21.30 ? 167 ASP M C 1 ATOM 4661 O O . ASP C 1 172 ? -39.996 54.932 15.929 1.00 21.25 ? 167 ASP M O 1 ATOM 4662 C CB . ASP C 1 172 ? -37.297 55.427 16.865 1.00 28.50 ? 167 ASP M CB 1 ATOM 4663 C CG . ASP C 1 172 ? -37.648 55.755 18.331 1.00 39.80 ? 167 ASP M CG 1 ATOM 4664 O OD1 . ASP C 1 172 ? -38.837 55.929 18.647 1.00 44.66 ? 167 ASP M OD1 1 ATOM 4665 O OD2 . ASP C 1 172 ? -36.734 55.857 19.166 1.00 44.97 ? 167 ASP M OD2 1 ATOM 4666 N N . SER C 1 173 ? -39.779 53.190 17.306 1.00 27.99 ? 168 SER M N 1 ATOM 4667 C CA . SER C 1 173 ? -41.185 52.920 17.521 1.00 35.63 ? 168 SER M CA 1 ATOM 4668 C C . SER C 1 173 ? -42.174 54.077 17.465 1.00 39.08 ? 168 SER M C 1 ATOM 4669 O O . SER C 1 173 ? -42.850 54.324 16.451 1.00 39.22 ? 168 SER M O 1 ATOM 4670 C CB . SER C 1 173 ? -41.239 52.207 18.839 1.00 33.25 ? 168 SER M CB 1 ATOM 4671 O OG . SER C 1 173 ? -40.115 51.322 18.824 1.00 41.62 ? 168 SER M OG 1 ATOM 4672 N N . LYS C 1 174 ? -42.249 54.855 18.528 1.00 37.46 ? 169 LYS M N 1 ATOM 4673 C CA . LYS C 1 174 ? -43.216 55.923 18.502 1.00 40.70 ? 169 LYS M CA 1 ATOM 4674 C C . LYS C 1 174 ? -42.303 57.109 18.734 1.00 34.93 ? 169 LYS M C 1 ATOM 4675 O O . LYS C 1 174 ? -41.637 57.221 19.764 1.00 31.56 ? 169 LYS M O 1 ATOM 4676 C CB . LYS C 1 174 ? -44.205 55.630 19.613 1.00 51.91 ? 169 LYS M CB 1 ATOM 4677 C CG . LYS C 1 174 ? -44.929 54.248 19.554 1.00 57.05 ? 169 LYS M CG 1 ATOM 4678 C CD . LYS C 1 174 ? -45.359 53.785 20.976 1.00 61.19 ? 169 LYS M CD 1 ATOM 4679 C CE . LYS C 1 174 ? -46.347 54.774 21.645 1.00 62.35 ? 169 LYS M CE 1 ATOM 4680 N NZ . LYS C 1 174 ? -46.537 54.525 23.055 1.00 57.29 ? 169 LYS M NZ 1 ATOM 4681 N N . ASP C 1 175 ? -42.185 57.780 17.586 1.00 28.52 ? 170 ASP M N 1 ATOM 4682 C CA . ASP C 1 175 ? -41.335 58.926 17.239 1.00 25.30 ? 170 ASP M CA 1 ATOM 4683 C C . ASP C 1 175 ? -40.959 58.717 15.773 1.00 23.19 ? 170 ASP M C 1 ATOM 4684 O O . ASP C 1 175 ? -40.701 59.647 15.011 1.00 20.55 ? 170 ASP M O 1 ATOM 4685 C CB . ASP C 1 175 ? -40.047 58.999 18.079 1.00 32.51 ? 170 ASP M CB 1 ATOM 4686 C CG . ASP C 1 175 ? -38.785 59.456 17.375 1.00 38.04 ? 170 ASP M CG 1 ATOM 4687 O OD1 . ASP C 1 175 ? -38.556 60.644 17.217 1.00 46.15 ? 170 ASP M OD1 1 ATOM 4688 O OD2 . ASP C 1 175 ? -38.030 58.604 16.945 1.00 45.67 ? 170 ASP M OD2 1 ATOM 4689 N N . SER C 1 176 ? -40.845 57.450 15.380 1.00 19.74 ? 171 SER M N 1 ATOM 4690 C CA . SER C 1 176 ? -40.656 57.048 13.999 1.00 17.93 ? 171 SER M CA 1 ATOM 4691 C C . SER C 1 176 ? -39.401 57.493 13.251 1.00 20.05 ? 171 SER M C 1 ATOM 4692 O O . SER C 1 176 ? -39.331 57.365 12.031 1.00 22.91 ? 171 SER M O 1 ATOM 4693 C CB . SER C 1 176 ? -41.942 57.466 13.325 1.00 20.95 ? 171 SER M CB 1 ATOM 4694 O OG . SER C 1 176 ? -43.004 56.919 14.143 1.00 23.87 ? 171 SER M OG 1 ATOM 4695 N N . THR C 1 177 ? -38.348 57.932 13.952 1.00 18.56 ? 172 THR M N 1 ATOM 4696 C CA . THR C 1 177 ? -37.108 58.290 13.311 1.00 15.11 ? 172 THR M CA 1 ATOM 4697 C C . THR C 1 177 ? -36.125 57.110 13.273 1.00 15.82 ? 172 THR M C 1 ATOM 4698 O O . THR C 1 177 ? -36.421 55.983 13.671 1.00 16.57 ? 172 THR M O 1 ATOM 4699 C CB . THR C 1 177 ? -36.499 59.522 14.053 1.00 15.45 ? 172 THR M CB 1 ATOM 4700 O OG1 . THR C 1 177 ? -36.027 59.128 15.333 1.00 18.59 ? 172 THR M OG1 1 ATOM 4701 C CG2 . THR C 1 177 ? -37.532 60.628 14.161 1.00 11.10 ? 172 THR M CG2 1 ATOM 4702 N N . TYR C 1 178 ? -34.971 57.311 12.657 1.00 12.43 ? 173 TYR M N 1 ATOM 4703 C CA . TYR C 1 178 ? -33.863 56.391 12.659 1.00 6.99 ? 173 TYR M CA 1 ATOM 4704 C C . TYR C 1 178 ? -32.768 57.105 13.450 1.00 10.47 ? 173 TYR M C 1 ATOM 4705 O O . TYR C 1 178 ? -32.953 58.270 13.843 1.00 7.49 ? 173 TYR M O 1 ATOM 4706 C CB . TYR C 1 178 ? -33.438 56.154 11.239 1.00 2.00 ? 173 TYR M CB 1 ATOM 4707 C CG . TYR C 1 178 ? -34.421 55.257 10.513 1.00 8.62 ? 173 TYR M CG 1 ATOM 4708 C CD1 . TYR C 1 178 ? -34.460 53.929 10.866 1.00 15.39 ? 173 TYR M CD1 1 ATOM 4709 C CD2 . TYR C 1 178 ? -35.264 55.729 9.538 1.00 6.39 ? 173 TYR M CD2 1 ATOM 4710 C CE1 . TYR C 1 178 ? -35.323 53.050 10.264 1.00 14.93 ? 173 TYR M CE1 1 ATOM 4711 C CE2 . TYR C 1 178 ? -36.137 54.853 8.929 1.00 13.13 ? 173 TYR M CE2 1 ATOM 4712 C CZ . TYR C 1 178 ? -36.166 53.515 9.295 1.00 19.20 ? 173 TYR M CZ 1 ATOM 4713 O OH . TYR C 1 178 ? -37.055 52.605 8.725 1.00 28.07 ? 173 TYR M OH 1 ATOM 4714 N N . SER C 1 179 ? -31.625 56.457 13.692 1.00 7.30 ? 174 SER M N 1 ATOM 4715 C CA . SER C 1 179 ? -30.442 57.028 14.306 1.00 3.08 ? 174 SER M CA 1 ATOM 4716 C C . SER C 1 179 ? -29.312 56.166 13.815 1.00 7.05 ? 174 SER M C 1 ATOM 4717 O O . SER C 1 179 ? -29.542 54.985 13.558 1.00 9.79 ? 174 SER M O 1 ATOM 4718 C CB . SER C 1 179 ? -30.475 56.942 15.803 1.00 5.79 ? 174 SER M CB 1 ATOM 4719 O OG . SER C 1 179 ? -31.465 57.798 16.374 1.00 9.74 ? 174 SER M OG 1 ATOM 4720 N N . MET C 1 180 ? -28.101 56.701 13.664 1.00 14.21 ? 175 MET M N 1 ATOM 4721 C CA . MET C 1 180 ? -26.958 55.996 13.081 1.00 11.94 ? 175 MET M CA 1 ATOM 4722 C C . MET C 1 180 ? -25.734 56.348 13.904 1.00 9.84 ? 175 MET M C 1 ATOM 4723 O O . MET C 1 180 ? -25.759 57.346 14.627 1.00 18.44 ? 175 MET M O 1 ATOM 4724 C CB . MET C 1 180 ? -26.792 56.457 11.636 1.00 10.21 ? 175 MET M CB 1 ATOM 4725 C CG . MET C 1 180 ? -25.631 55.873 10.888 1.00 14.60 ? 175 MET M CG 1 ATOM 4726 S SD . MET C 1 180 ? -25.081 57.004 9.593 1.00 26.74 ? 175 MET M SD 1 ATOM 4727 C CE . MET C 1 180 ? -24.180 56.012 8.433 1.00 16.51 ? 175 MET M CE 1 ATOM 4728 N N . SER C 1 181 ? -24.648 55.607 13.848 1.00 7.83 ? 176 SER M N 1 ATOM 4729 C CA . SER C 1 181 ? -23.453 55.937 14.596 1.00 13.50 ? 176 SER M CA 1 ATOM 4730 C C . SER C 1 181 ? -22.272 55.478 13.772 1.00 11.52 ? 176 SER M C 1 ATOM 4731 O O . SER C 1 181 ? -22.262 54.334 13.318 1.00 12.81 ? 176 SER M O 1 ATOM 4732 C CB . SER C 1 181 ? -23.488 55.213 15.927 1.00 24.29 ? 176 SER M CB 1 ATOM 4733 O OG . SER C 1 181 ? -22.302 55.289 16.721 1.00 34.87 ? 176 SER M OG 1 ATOM 4734 N N . SER C 1 182 ? -21.321 56.371 13.527 1.00 13.07 ? 177 SER M N 1 ATOM 4735 C CA . SER C 1 182 ? -20.163 56.065 12.709 1.00 14.48 ? 177 SER M CA 1 ATOM 4736 C C . SER C 1 182 ? -18.973 56.290 13.641 1.00 14.02 ? 177 SER M C 1 ATOM 4737 O O . SER C 1 182 ? -18.931 57.292 14.379 1.00 10.50 ? 177 SER M O 1 ATOM 4738 C CB . SER C 1 182 ? -20.175 57.015 11.498 1.00 12.66 ? 177 SER M CB 1 ATOM 4739 O OG . SER C 1 182 ? -19.107 56.832 10.563 1.00 15.58 ? 177 SER M OG 1 ATOM 4740 N N . THR C 1 183 ? -18.035 55.346 13.655 1.00 10.75 ? 178 THR M N 1 ATOM 4741 C CA . THR C 1 183 ? -16.857 55.413 14.492 1.00 12.38 ? 178 THR M CA 1 ATOM 4742 C C . THR C 1 183 ? -15.750 55.214 13.496 1.00 14.60 ? 178 THR M C 1 ATOM 4743 O O . THR C 1 183 ? -15.893 54.339 12.610 1.00 8.12 ? 178 THR M O 1 ATOM 4744 C CB . THR C 1 183 ? -16.838 54.268 15.535 1.00 17.32 ? 178 THR M CB 1 ATOM 4745 O OG1 . THR C 1 183 ? -17.863 54.610 16.440 1.00 19.63 ? 178 THR M OG1 1 ATOM 4746 C CG2 . THR C 1 183 ? -15.538 54.081 16.316 1.00 13.53 ? 178 THR M CG2 1 ATOM 4747 N N . LEU C 1 184 ? -14.688 56.031 13.694 1.00 13.32 ? 179 LEU M N 1 ATOM 4748 C CA . LEU C 1 184 ? -13.504 56.063 12.830 1.00 12.94 ? 179 LEU M CA 1 ATOM 4749 C C . LEU C 1 184 ? -12.402 55.682 13.784 1.00 14.55 ? 179 LEU M C 1 ATOM 4750 O O . LEU C 1 184 ? -12.263 56.354 14.816 1.00 10.06 ? 179 LEU M O 1 ATOM 4751 C CB . LEU C 1 184 ? -13.352 57.478 12.300 1.00 13.08 ? 179 LEU M CB 1 ATOM 4752 C CG . LEU C 1 184 ? -12.216 58.047 11.430 1.00 16.93 ? 179 LEU M CG 1 ATOM 4753 C CD1 . LEU C 1 184 ? -11.319 58.847 12.393 1.00 14.43 ? 179 LEU M CD1 1 ATOM 4754 C CD2 . LEU C 1 184 ? -11.562 56.963 10.547 1.00 2.00 ? 179 LEU M CD2 1 ATOM 4755 N N . THR C 1 185 ? -11.698 54.571 13.505 1.00 20.18 ? 180 THR M N 1 ATOM 4756 C CA . THR C 1 185 ? -10.669 54.081 14.418 1.00 21.33 ? 180 THR M CA 1 ATOM 4757 C C . THR C 1 185 ? -9.354 54.024 13.666 1.00 16.45 ? 180 THR M C 1 ATOM 4758 O O . THR C 1 185 ? -9.198 53.458 12.586 1.00 4.91 ? 180 THR M O 1 ATOM 4759 C CB . THR C 1 185 ? -11.020 52.652 14.997 1.00 26.32 ? 180 THR M CB 1 ATOM 4760 O OG1 . THR C 1 185 ? -12.248 52.723 15.728 1.00 28.96 ? 180 THR M OG1 1 ATOM 4761 C CG2 . THR C 1 185 ? -9.995 52.181 16.005 1.00 29.39 ? 180 THR M CG2 1 ATOM 4762 N N . LEU C 1 186 ? -8.440 54.719 14.305 1.00 18.15 ? 181 LEU M N 1 ATOM 4763 C CA . LEU C 1 186 ? -7.076 54.894 13.881 1.00 18.35 ? 181 LEU M CA 1 ATOM 4764 C C . LEU C 1 186 ? -6.239 54.378 15.068 1.00 15.98 ? 181 LEU M C 1 ATOM 4765 O O . LEU C 1 186 ? -6.725 54.154 16.181 1.00 6.94 ? 181 LEU M O 1 ATOM 4766 C CB . LEU C 1 186 ? -6.775 56.383 13.670 1.00 15.98 ? 181 LEU M CB 1 ATOM 4767 C CG . LEU C 1 186 ? -7.860 57.412 13.348 1.00 18.66 ? 181 LEU M CG 1 ATOM 4768 C CD1 . LEU C 1 186 ? -7.447 58.812 13.841 1.00 18.52 ? 181 LEU M CD1 1 ATOM 4769 C CD2 . LEU C 1 186 ? -8.128 57.361 11.859 1.00 13.28 ? 181 LEU M CD2 1 ATOM 4770 N N . THR C 1 187 ? -4.939 54.241 14.858 1.00 19.12 ? 182 THR M N 1 ATOM 4771 C CA . THR C 1 187 ? -3.992 53.864 15.910 1.00 23.23 ? 182 THR M CA 1 ATOM 4772 C C . THR C 1 187 ? -3.589 55.157 16.646 1.00 26.21 ? 182 THR M C 1 ATOM 4773 O O . THR C 1 187 ? -3.738 56.228 16.040 1.00 29.85 ? 182 THR M O 1 ATOM 4774 C CB . THR C 1 187 ? -2.778 53.188 15.249 1.00 21.97 ? 182 THR M CB 1 ATOM 4775 O OG1 . THR C 1 187 ? -1.980 54.171 14.566 1.00 30.17 ? 182 THR M OG1 1 ATOM 4776 C CG2 . THR C 1 187 ? -3.244 52.198 14.202 1.00 27.14 ? 182 THR M CG2 1 ATOM 4777 N N . LYS C 1 188 ? -3.032 55.180 17.867 1.00 22.48 ? 183 LYS M N 1 ATOM 4778 C CA . LYS C 1 188 ? -2.661 56.433 18.500 1.00 19.05 ? 183 LYS M CA 1 ATOM 4779 C C . LYS C 1 188 ? -1.660 57.197 17.666 1.00 22.51 ? 183 LYS M C 1 ATOM 4780 O O . LYS C 1 188 ? -1.901 58.364 17.430 1.00 31.64 ? 183 LYS M O 1 ATOM 4781 C CB . LYS C 1 188 ? -2.026 56.238 19.854 1.00 15.61 ? 183 LYS M CB 1 ATOM 4782 C CG . LYS C 1 188 ? -1.712 57.550 20.543 1.00 17.48 ? 183 LYS M CG 1 ATOM 4783 C CD . LYS C 1 188 ? -1.299 57.219 21.965 1.00 30.63 ? 183 LYS M CD 1 ATOM 4784 C CE . LYS C 1 188 ? 0.176 57.412 22.307 1.00 35.20 ? 183 LYS M CE 1 ATOM 4785 N NZ . LYS C 1 188 ? 0.452 58.816 22.497 1.00 36.95 ? 183 LYS M NZ 1 ATOM 4786 N N . ASP C 1 189 ? -0.594 56.645 17.118 1.00 22.08 ? 184 ASP M N 1 ATOM 4787 C CA . ASP C 1 189 ? 0.363 57.497 16.460 1.00 29.93 ? 184 ASP M CA 1 ATOM 4788 C C . ASP C 1 189 ? -0.138 58.107 15.153 1.00 35.93 ? 184 ASP M C 1 ATOM 4789 O O . ASP C 1 189 ? 0.337 59.177 14.778 1.00 42.89 ? 184 ASP M O 1 ATOM 4790 C CB . ASP C 1 189 ? 1.641 56.692 16.249 1.00 36.92 ? 184 ASP M CB 1 ATOM 4791 C CG . ASP C 1 189 ? 2.495 56.614 17.509 1.00 40.97 ? 184 ASP M CG 1 ATOM 4792 O OD1 . ASP C 1 189 ? 2.248 55.723 18.326 1.00 44.23 ? 184 ASP M OD1 1 ATOM 4793 O OD2 . ASP C 1 189 ? 3.396 57.447 17.671 1.00 41.14 ? 184 ASP M OD2 1 ATOM 4794 N N . GLU C 1 190 ? -1.119 57.527 14.451 1.00 33.23 ? 185 GLU M N 1 ATOM 4795 C CA . GLU C 1 190 ? -1.679 58.118 13.233 1.00 27.65 ? 185 GLU M CA 1 ATOM 4796 C C . GLU C 1 190 ? -2.696 59.205 13.598 1.00 23.87 ? 185 GLU M C 1 ATOM 4797 O O . GLU C 1 190 ? -2.858 60.201 12.879 1.00 22.35 ? 185 GLU M O 1 ATOM 4798 C CB . GLU C 1 190 ? -2.270 56.948 12.423 1.00 33.17 ? 185 GLU M CB 1 ATOM 4799 C CG . GLU C 1 190 ? -3.276 57.081 11.273 1.00 37.69 ? 185 GLU M CG 1 ATOM 4800 C CD . GLU C 1 190 ? -2.888 57.847 10.016 1.00 44.99 ? 185 GLU M CD 1 ATOM 4801 O OE1 . GLU C 1 190 ? -1.740 58.300 9.900 1.00 52.13 ? 185 GLU M OE1 1 ATOM 4802 O OE2 . GLU C 1 190 ? -3.766 57.993 9.153 1.00 43.91 ? 185 GLU M OE2 1 ATOM 4803 N N . TYR C 1 191 ? -3.367 59.064 14.744 1.00 18.64 ? 186 TYR M N 1 ATOM 4804 C CA . TYR C 1 191 ? -4.277 60.069 15.257 1.00 18.94 ? 186 TYR M CA 1 ATOM 4805 C C . TYR C 1 191 ? -3.471 61.306 15.589 1.00 21.85 ? 186 TYR M C 1 ATOM 4806 O O . TYR C 1 191 ? -3.940 62.443 15.450 1.00 25.53 ? 186 TYR M O 1 ATOM 4807 C CB . TYR C 1 191 ? -4.960 59.613 16.529 1.00 15.41 ? 186 TYR M CB 1 ATOM 4808 C CG . TYR C 1 191 ? -5.765 60.675 17.260 1.00 14.22 ? 186 TYR M CG 1 ATOM 4809 C CD1 . TYR C 1 191 ? -6.941 61.140 16.706 1.00 15.01 ? 186 TYR M CD1 1 ATOM 4810 C CD2 . TYR C 1 191 ? -5.335 61.159 18.485 1.00 16.02 ? 186 TYR M CD2 1 ATOM 4811 C CE1 . TYR C 1 191 ? -7.703 62.087 17.382 1.00 12.40 ? 186 TYR M CE1 1 ATOM 4812 C CE2 . TYR C 1 191 ? -6.092 62.107 19.167 1.00 15.47 ? 186 TYR M CE2 1 ATOM 4813 C CZ . TYR C 1 191 ? -7.277 62.562 18.605 1.00 11.05 ? 186 TYR M CZ 1 ATOM 4814 O OH . TYR C 1 191 ? -8.067 63.484 19.266 1.00 12.11 ? 186 TYR M OH 1 ATOM 4815 N N . GLU C 1 192 ? -2.263 61.062 16.068 1.00 18.45 ? 187 GLU M N 1 ATOM 4816 C CA . GLU C 1 192 ? -1.398 62.156 16.435 1.00 20.88 ? 187 GLU M CA 1 ATOM 4817 C C . GLU C 1 192 ? -0.769 62.727 15.177 1.00 19.07 ? 187 GLU M C 1 ATOM 4818 O O . GLU C 1 192 ? -0.293 63.841 15.165 1.00 20.97 ? 187 GLU M O 1 ATOM 4819 C CB . GLU C 1 192 ? -0.329 61.665 17.379 1.00 23.37 ? 187 GLU M CB 1 ATOM 4820 C CG . GLU C 1 192 ? -0.858 60.783 18.495 1.00 19.37 ? 187 GLU M CG 1 ATOM 4821 C CD . GLU C 1 192 ? -0.710 61.327 19.887 1.00 19.70 ? 187 GLU M CD 1 ATOM 4822 O OE1 . GLU C 1 192 ? -1.568 62.104 20.305 1.00 26.71 ? 187 GLU M OE1 1 ATOM 4823 O OE2 . GLU C 1 192 ? 0.251 60.952 20.549 1.00 12.78 ? 187 GLU M OE2 1 ATOM 4824 N N . ARG C 1 193 ? -0.795 62.068 14.040 1.00 22.15 ? 188 ARG M N 1 ATOM 4825 C CA . ARG C 1 193 ? -0.212 62.623 12.835 1.00 26.03 ? 188 ARG M CA 1 ATOM 4826 C C . ARG C 1 193 ? -1.175 63.608 12.180 1.00 26.33 ? 188 ARG M C 1 ATOM 4827 O O . ARG C 1 193 ? -1.051 63.912 10.987 1.00 27.19 ? 188 ARG M O 1 ATOM 4828 C CB . ARG C 1 193 ? 0.127 61.454 11.870 1.00 30.30 ? 188 ARG M CB 1 ATOM 4829 C CG . ARG C 1 193 ? 1.431 60.752 12.199 1.00 33.63 ? 188 ARG M CG 1 ATOM 4830 C CD . ARG C 1 193 ? 1.612 59.551 11.284 1.00 49.12 ? 188 ARG M CD 1 ATOM 4831 N NE . ARG C 1 193 ? 1.445 58.273 11.979 1.00 62.00 ? 188 ARG M NE 1 ATOM 4832 C CZ . ARG C 1 193 ? 2.417 57.590 12.628 1.00 64.89 ? 188 ARG M CZ 1 ATOM 4833 N NH1 . ARG C 1 193 ? 3.688 57.997 12.751 1.00 65.16 ? 188 ARG M NH1 1 ATOM 4834 N NH2 . ARG C 1 193 ? 2.084 56.430 13.196 1.00 65.41 ? 188 ARG M NH2 1 ATOM 4835 N N . HIS C 1 194 ? -2.223 64.095 12.839 1.00 29.58 ? 189 HIS M N 1 ATOM 4836 C CA . HIS C 1 194 ? -3.245 64.911 12.181 1.00 25.77 ? 189 HIS M CA 1 ATOM 4837 C C . HIS C 1 194 ? -3.904 65.839 13.173 1.00 24.53 ? 189 HIS M C 1 ATOM 4838 O O . HIS C 1 194 ? -3.657 65.752 14.386 1.00 14.66 ? 189 HIS M O 1 ATOM 4839 C CB . HIS C 1 194 ? -4.356 64.090 11.588 1.00 21.35 ? 189 HIS M CB 1 ATOM 4840 C CG . HIS C 1 194 ? -3.876 63.062 10.614 1.00 27.44 ? 189 HIS M CG 1 ATOM 4841 N ND1 . HIS C 1 194 ? -3.742 61.774 10.855 1.00 35.43 ? 189 HIS M ND1 1 ATOM 4842 C CD2 . HIS C 1 194 ? -3.489 63.310 9.328 1.00 31.34 ? 189 HIS M CD2 1 ATOM 4843 C CE1 . HIS C 1 194 ? -3.291 61.226 9.760 1.00 36.18 ? 189 HIS M CE1 1 ATOM 4844 N NE2 . HIS C 1 194 ? -3.143 62.151 8.851 1.00 34.29 ? 189 HIS M NE2 1 ATOM 4845 N N . ASN C 1 195 ? -4.817 66.661 12.640 1.00 19.37 ? 190 ASN M N 1 ATOM 4846 C CA . ASN C 1 195 ? -5.363 67.672 13.505 1.00 27.04 ? 190 ASN M CA 1 ATOM 4847 C C . ASN C 1 195 ? -6.813 68.066 13.305 1.00 26.77 ? 190 ASN M C 1 ATOM 4848 O O . ASN C 1 195 ? -7.431 68.639 14.199 1.00 21.32 ? 190 ASN M O 1 ATOM 4849 C CB . ASN C 1 195 ? -4.384 68.847 13.374 1.00 32.69 ? 190 ASN M CB 1 ATOM 4850 C CG . ASN C 1 195 ? -4.716 70.061 14.212 1.00 36.60 ? 190 ASN M CG 1 ATOM 4851 O OD1 . ASN C 1 195 ? -4.467 70.160 15.414 1.00 34.62 ? 190 ASN M OD1 1 ATOM 4852 N ND2 . ASN C 1 195 ? -5.275 71.038 13.513 1.00 40.59 ? 190 ASN M ND2 1 ATOM 4853 N N . SER C 1 196 ? -7.428 67.772 12.168 1.00 28.24 ? 191 SER M N 1 ATOM 4854 C CA . SER C 1 196 ? -8.837 68.105 12.000 1.00 32.59 ? 191 SER M CA 1 ATOM 4855 C C . SER C 1 196 ? -9.563 66.813 11.665 1.00 31.17 ? 191 SER M C 1 ATOM 4856 O O . SER C 1 196 ? -9.133 66.090 10.748 1.00 32.37 ? 191 SER M O 1 ATOM 4857 C CB . SER C 1 196 ? -9.072 69.084 10.851 1.00 32.98 ? 191 SER M CB 1 ATOM 4858 O OG . SER C 1 196 ? -8.507 70.359 11.103 1.00 39.48 ? 191 SER M OG 1 ATOM 4859 N N . TYR C 1 197 ? -10.596 66.502 12.439 1.00 22.35 ? 192 TYR M N 1 ATOM 4860 C CA . TYR C 1 197 ? -11.391 65.331 12.184 1.00 17.07 ? 192 TYR M CA 1 ATOM 4861 C C . TYR C 1 197 ? -12.757 65.994 12.033 1.00 17.93 ? 192 TYR M C 1 ATOM 4862 O O . TYR C 1 197 ? -13.198 66.796 12.886 1.00 14.12 ? 192 TYR M O 1 ATOM 4863 C CB . TYR C 1 197 ? -11.242 64.400 13.401 1.00 14.27 ? 192 TYR M CB 1 ATOM 4864 C CG . TYR C 1 197 ? -9.852 63.784 13.534 1.00 12.76 ? 192 TYR M CG 1 ATOM 4865 C CD1 . TYR C 1 197 ? -9.592 62.626 12.842 1.00 13.63 ? 192 TYR M CD1 1 ATOM 4866 C CD2 . TYR C 1 197 ? -8.841 64.386 14.277 1.00 14.97 ? 192 TYR M CD2 1 ATOM 4867 C CE1 . TYR C 1 197 ? -8.337 62.063 12.881 1.00 17.99 ? 192 TYR M CE1 1 ATOM 4868 C CE2 . TYR C 1 197 ? -7.572 63.841 14.314 1.00 11.87 ? 192 TYR M CE2 1 ATOM 4869 C CZ . TYR C 1 197 ? -7.334 62.674 13.605 1.00 18.58 ? 192 TYR M CZ 1 ATOM 4870 O OH . TYR C 1 197 ? -6.076 62.094 13.588 1.00 23.49 ? 192 TYR M OH 1 ATOM 4871 N N . THR C 1 198 ? -13.360 65.702 10.882 1.00 14.21 ? 193 THR M N 1 ATOM 4872 C CA . THR C 1 198 ? -14.616 66.284 10.448 1.00 14.66 ? 193 THR M CA 1 ATOM 4873 C C . THR C 1 198 ? -15.562 65.143 10.090 1.00 18.44 ? 193 THR M C 1 ATOM 4874 O O . THR C 1 198 ? -15.280 64.270 9.248 1.00 16.54 ? 193 THR M O 1 ATOM 4875 C CB . THR C 1 198 ? -14.347 67.210 9.197 1.00 18.29 ? 193 THR M CB 1 ATOM 4876 O OG1 . THR C 1 198 ? -13.810 68.443 9.661 1.00 18.60 ? 193 THR M OG1 1 ATOM 4877 C CG2 . THR C 1 198 ? -15.601 67.546 8.392 1.00 18.01 ? 193 THR M CG2 1 ATOM 4878 N N . CYS C 1 199 ? -16.717 65.164 10.744 1.00 23.06 ? 194 CYS M N 1 ATOM 4879 C CA . CYS C 1 199 ? -17.798 64.227 10.476 1.00 21.32 ? 194 CYS M CA 1 ATOM 4880 C C . CYS C 1 199 ? -18.778 65.003 9.586 1.00 18.56 ? 194 CYS M C 1 ATOM 4881 O O . CYS C 1 199 ? -19.300 66.061 9.990 1.00 17.95 ? 194 CYS M O 1 ATOM 4882 C CB . CYS C 1 199 ? -18.406 63.857 11.802 1.00 21.72 ? 194 CYS M CB 1 ATOM 4883 S SG . CYS C 1 199 ? -19.733 62.688 11.499 1.00 29.64 ? 194 CYS M SG 1 ATOM 4884 N N . GLU C 1 200 ? -19.022 64.573 8.361 1.00 11.42 ? 195 GLU M N 1 ATOM 4885 C CA . GLU C 1 200 ? -19.844 65.368 7.491 1.00 19.83 ? 195 GLU M CA 1 ATOM 4886 C C . GLU C 1 200 ? -21.030 64.595 6.968 1.00 25.56 ? 195 GLU M C 1 ATOM 4887 O O . GLU C 1 200 ? -20.913 63.675 6.158 1.00 32.43 ? 195 GLU M O 1 ATOM 4888 C CB . GLU C 1 200 ? -18.951 65.810 6.423 1.00 23.47 ? 195 GLU M CB 1 ATOM 4889 C CG . GLU C 1 200 ? -19.681 66.581 5.385 1.00 32.39 ? 195 GLU M CG 1 ATOM 4890 C CD . GLU C 1 200 ? -18.782 66.777 4.188 1.00 41.03 ? 195 GLU M CD 1 ATOM 4891 O OE1 . GLU C 1 200 ? -17.887 67.621 4.272 1.00 41.96 ? 195 GLU M OE1 1 ATOM 4892 O OE2 . GLU C 1 200 ? -18.981 66.076 3.191 1.00 44.95 ? 195 GLU M OE2 1 ATOM 4893 N N . ALA C 1 201 ? -22.190 64.966 7.464 1.00 29.56 ? 196 ALA M N 1 ATOM 4894 C CA . ALA C 1 201 ? -23.451 64.325 7.150 1.00 29.90 ? 196 ALA M CA 1 ATOM 4895 C C . ALA C 1 201 ? -24.212 64.964 5.987 1.00 32.75 ? 196 ALA M C 1 ATOM 4896 O O . ALA C 1 201 ? -24.371 66.190 5.923 1.00 28.94 ? 196 ALA M O 1 ATOM 4897 C CB . ALA C 1 201 ? -24.320 64.378 8.394 1.00 31.49 ? 196 ALA M CB 1 ATOM 4898 N N . THR C 1 202 ? -24.756 64.157 5.085 1.00 31.93 ? 197 THR M N 1 ATOM 4899 C CA . THR C 1 202 ? -25.507 64.633 3.931 1.00 30.89 ? 197 THR M CA 1 ATOM 4900 C C . THR C 1 202 ? -26.832 63.909 4.002 1.00 31.71 ? 197 THR M C 1 ATOM 4901 O O . THR C 1 202 ? -26.863 62.676 4.002 1.00 32.29 ? 197 THR M O 1 ATOM 4902 C CB . THR C 1 202 ? -24.701 64.256 2.708 1.00 34.16 ? 197 THR M CB 1 ATOM 4903 O OG1 . THR C 1 202 ? -23.546 65.062 2.847 1.00 42.12 ? 197 THR M OG1 1 ATOM 4904 C CG2 . THR C 1 202 ? -25.382 64.443 1.371 1.00 33.89 ? 197 THR M CG2 1 ATOM 4905 N N . HIS C 1 203 ? -27.953 64.598 4.088 1.00 34.93 ? 198 HIS M N 1 ATOM 4906 C CA . HIS C 1 203 ? -29.232 63.931 4.261 1.00 37.39 ? 198 HIS M CA 1 ATOM 4907 C C . HIS C 1 203 ? -30.265 64.647 3.421 1.00 42.94 ? 198 HIS M C 1 ATOM 4908 O O . HIS C 1 203 ? -30.221 65.875 3.433 1.00 48.39 ? 198 HIS M O 1 ATOM 4909 C CB . HIS C 1 203 ? -29.668 63.988 5.726 1.00 28.70 ? 198 HIS M CB 1 ATOM 4910 C CG . HIS C 1 203 ? -30.977 63.252 5.982 1.00 24.46 ? 198 HIS M CG 1 ATOM 4911 N ND1 . HIS C 1 203 ? -31.451 62.153 5.384 1.00 20.35 ? 198 HIS M ND1 1 ATOM 4912 C CD2 . HIS C 1 203 ? -31.869 63.640 6.946 1.00 21.21 ? 198 HIS M CD2 1 ATOM 4913 C CE1 . HIS C 1 203 ? -32.583 61.870 5.962 1.00 20.70 ? 198 HIS M CE1 1 ATOM 4914 N NE2 . HIS C 1 203 ? -32.826 62.765 6.890 1.00 23.00 ? 198 HIS M NE2 1 ATOM 4915 N N . LYS C 1 204 ? -31.243 63.964 2.791 1.00 43.54 ? 199 LYS M N 1 ATOM 4916 C CA . LYS C 1 204 ? -32.287 64.620 1.992 1.00 35.81 ? 199 LYS M CA 1 ATOM 4917 C C . LYS C 1 204 ? -32.957 65.859 2.619 1.00 30.53 ? 199 LYS M C 1 ATOM 4918 O O . LYS C 1 204 ? -33.659 66.530 1.889 1.00 25.98 ? 199 LYS M O 1 ATOM 4919 C CB . LYS C 1 204 ? -33.293 63.514 1.644 1.00 34.52 ? 199 LYS M CB 1 ATOM 4920 C CG . LYS C 1 204 ? -34.375 63.821 0.614 1.00 31.99 ? 199 LYS M CG 1 ATOM 4921 C CD . LYS C 1 204 ? -35.648 64.316 1.292 1.00 28.28 ? 199 LYS M CD 1 ATOM 4922 C CE . LYS C 1 204 ? -36.779 64.211 0.311 1.00 31.35 ? 199 LYS M CE 1 ATOM 4923 N NZ . LYS C 1 204 ? -37.962 63.685 0.970 1.00 36.78 ? 199 LYS M NZ 1 ATOM 4924 N N . THR C 1 205 ? -32.823 66.226 3.911 1.00 27.93 ? 200 THR M N 1 ATOM 4925 C CA . THR C 1 205 ? -33.338 67.483 4.414 1.00 31.87 ? 200 THR M CA 1 ATOM 4926 C C . THR C 1 205 ? -32.340 68.635 4.236 1.00 35.08 ? 200 THR M C 1 ATOM 4927 O O . THR C 1 205 ? -32.543 69.703 4.817 1.00 36.27 ? 200 THR M O 1 ATOM 4928 C CB . THR C 1 205 ? -33.754 67.364 5.941 1.00 33.49 ? 200 THR M CB 1 ATOM 4929 O OG1 . THR C 1 205 ? -32.712 66.857 6.756 1.00 33.25 ? 200 THR M OG1 1 ATOM 4930 C CG2 . THR C 1 205 ? -34.874 66.366 6.088 1.00 38.51 ? 200 THR M CG2 1 ATOM 4931 N N . SER C 1 206 ? -31.253 68.523 3.462 1.00 42.42 ? 201 SER M N 1 ATOM 4932 C CA . SER C 1 206 ? -30.295 69.617 3.257 1.00 49.83 ? 201 SER M CA 1 ATOM 4933 C C . SER C 1 206 ? -29.350 69.358 2.061 1.00 55.96 ? 201 SER M C 1 ATOM 4934 O O . SER C 1 206 ? -28.989 68.222 1.707 1.00 61.29 ? 201 SER M O 1 ATOM 4935 C CB . SER C 1 206 ? -29.451 69.819 4.530 1.00 47.84 ? 201 SER M CB 1 ATOM 4936 O OG . SER C 1 206 ? -29.020 71.161 4.680 1.00 42.96 ? 201 SER M OG 1 ATOM 4937 N N . THR C 1 207 ? -29.025 70.437 1.338 1.00 56.57 ? 202 THR M N 1 ATOM 4938 C CA . THR C 1 207 ? -28.059 70.401 0.230 1.00 53.49 ? 202 THR M CA 1 ATOM 4939 C C . THR C 1 207 ? -26.698 70.776 0.764 1.00 51.63 ? 202 THR M C 1 ATOM 4940 O O . THR C 1 207 ? -25.664 70.519 0.151 1.00 49.59 ? 202 THR M O 1 ATOM 4941 C CB . THR C 1 207 ? -28.398 71.394 -0.845 1.00 53.78 ? 202 THR M CB 1 ATOM 4942 O OG1 . THR C 1 207 ? -28.573 72.669 -0.201 1.00 56.38 ? 202 THR M OG1 1 ATOM 4943 C CG2 . THR C 1 207 ? -29.622 70.943 -1.614 1.00 52.41 ? 202 THR M CG2 1 ATOM 4944 N N . SER C 1 208 ? -26.797 71.519 1.871 1.00 51.37 ? 203 SER M N 1 ATOM 4945 C CA . SER C 1 208 ? -25.681 71.903 2.701 1.00 54.57 ? 203 SER M CA 1 ATOM 4946 C C . SER C 1 208 ? -25.406 70.714 3.630 1.00 55.06 ? 203 SER M C 1 ATOM 4947 O O . SER C 1 208 ? -26.352 70.056 4.091 1.00 54.19 ? 203 SER M O 1 ATOM 4948 C CB . SER C 1 208 ? -26.071 73.147 3.486 1.00 57.20 ? 203 SER M CB 1 ATOM 4949 O OG . SER C 1 208 ? -27.473 73.202 3.756 1.00 59.95 ? 203 SER M OG 1 ATOM 4950 N N . PRO C 1 209 ? -24.144 70.348 3.876 1.00 53.78 ? 204 PRO M N 1 ATOM 4951 C CA . PRO C 1 209 ? -23.793 69.244 4.749 1.00 51.88 ? 204 PRO M CA 1 ATOM 4952 C C . PRO C 1 209 ? -23.870 69.647 6.223 1.00 49.08 ? 204 PRO M C 1 ATOM 4953 O O . PRO C 1 209 ? -23.636 70.814 6.583 1.00 52.66 ? 204 PRO M O 1 ATOM 4954 C CB . PRO C 1 209 ? -22.414 68.875 4.257 1.00 52.00 ? 204 PRO M CB 1 ATOM 4955 C CG . PRO C 1 209 ? -21.782 70.211 3.953 1.00 52.70 ? 204 PRO M CG 1 ATOM 4956 C CD . PRO C 1 209 ? -22.945 70.967 3.308 1.00 55.53 ? 204 PRO M CD 1 ATOM 4957 N N . ILE C 1 210 ? -24.221 68.708 7.108 1.00 39.37 ? 205 ILE M N 1 ATOM 4958 C CA . ILE C 1 210 ? -24.197 68.959 8.536 1.00 27.51 ? 205 ILE M CA 1 ATOM 4959 C C . ILE C 1 210 ? -22.722 68.613 8.717 1.00 26.90 ? 205 ILE M C 1 ATOM 4960 O O . ILE C 1 210 ? -22.268 67.552 8.261 1.00 26.36 ? 205 ILE M O 1 ATOM 4961 C CB . ILE C 1 210 ? -25.056 67.969 9.360 1.00 25.52 ? 205 ILE M CB 1 ATOM 4962 C CG1 . ILE C 1 210 ? -26.405 67.572 8.757 1.00 25.71 ? 205 ILE M CG1 1 ATOM 4963 C CG2 . ILE C 1 210 ? -25.294 68.678 10.655 1.00 21.31 ? 205 ILE M CG2 1 ATOM 4964 C CD1 . ILE C 1 210 ? -27.431 68.678 8.482 1.00 24.77 ? 205 ILE M CD1 1 ATOM 4965 N N . VAL C 1 211 ? -21.931 69.539 9.246 1.00 24.25 ? 206 VAL M N 1 ATOM 4966 C CA . VAL C 1 211 ? -20.508 69.319 9.454 1.00 24.63 ? 206 VAL M CA 1 ATOM 4967 C C . VAL C 1 211 ? -20.253 69.610 10.909 1.00 25.41 ? 206 VAL M C 1 ATOM 4968 O O . VAL C 1 211 ? -20.541 70.706 11.418 1.00 24.13 ? 206 VAL M O 1 ATOM 4969 C CB . VAL C 1 211 ? -19.657 70.253 8.575 1.00 18.38 ? 206 VAL M CB 1 ATOM 4970 C CG1 . VAL C 1 211 ? -18.241 70.422 9.064 1.00 20.72 ? 206 VAL M CG1 1 ATOM 4971 C CG2 . VAL C 1 211 ? -19.488 69.579 7.253 1.00 22.03 ? 206 VAL M CG2 1 ATOM 4972 N N . LYS C 1 212 ? -19.749 68.578 11.567 1.00 22.96 ? 207 LYS M N 1 ATOM 4973 C CA . LYS C 1 212 ? -19.434 68.704 12.963 1.00 25.48 ? 207 LYS M CA 1 ATOM 4974 C C . LYS C 1 212 ? -17.941 68.453 13.026 1.00 24.39 ? 207 LYS M C 1 ATOM 4975 O O . LYS C 1 212 ? -17.457 67.532 12.353 1.00 28.47 ? 207 LYS M O 1 ATOM 4976 C CB . LYS C 1 212 ? -20.300 67.686 13.714 1.00 24.55 ? 207 LYS M CB 1 ATOM 4977 C CG . LYS C 1 212 ? -21.545 68.380 14.325 1.00 32.14 ? 207 LYS M CG 1 ATOM 4978 C CD . LYS C 1 212 ? -21.082 69.268 15.501 1.00 39.53 ? 207 LYS M CD 1 ATOM 4979 C CE . LYS C 1 212 ? -22.145 69.708 16.530 1.00 43.30 ? 207 LYS M CE 1 ATOM 4980 N NZ . LYS C 1 212 ? -21.547 69.967 17.844 1.00 40.28 ? 207 LYS M NZ 1 ATOM 4981 N N . SER C 1 213 ? -17.151 69.245 13.749 1.00 20.90 ? 208 SER M N 1 ATOM 4982 C CA . SER C 1 213 ? -15.723 69.010 13.706 1.00 22.64 ? 208 SER M CA 1 ATOM 4983 C C . SER C 1 213 ? -15.073 69.491 14.971 1.00 21.12 ? 208 SER M C 1 ATOM 4984 O O . SER C 1 213 ? -15.745 70.164 15.754 1.00 22.81 ? 208 SER M O 1 ATOM 4985 C CB . SER C 1 213 ? -15.135 69.741 12.516 1.00 23.98 ? 208 SER M CB 1 ATOM 4986 O OG . SER C 1 213 ? -13.821 69.284 12.212 1.00 30.82 ? 208 SER M OG 1 ATOM 4987 N N . PHE C 1 214 ? -13.818 69.055 15.170 1.00 23.00 ? 209 PHE M N 1 ATOM 4988 C CA . PHE C 1 214 ? -12.946 69.528 16.244 1.00 24.15 ? 209 PHE M CA 1 ATOM 4989 C C . PHE C 1 214 ? -11.499 69.528 15.748 1.00 22.13 ? 209 PHE M C 1 ATOM 4990 O O . PHE C 1 214 ? -11.130 68.926 14.734 1.00 21.96 ? 209 PHE M O 1 ATOM 4991 C CB . PHE C 1 214 ? -13.035 68.650 17.509 1.00 24.99 ? 209 PHE M CB 1 ATOM 4992 C CG . PHE C 1 214 ? -12.568 67.195 17.389 1.00 29.63 ? 209 PHE M CG 1 ATOM 4993 C CD1 . PHE C 1 214 ? -13.274 66.276 16.629 1.00 29.57 ? 209 PHE M CD1 1 ATOM 4994 C CD2 . PHE C 1 214 ? -11.423 66.789 18.051 1.00 27.74 ? 209 PHE M CD2 1 ATOM 4995 C CE1 . PHE C 1 214 ? -12.831 64.976 16.540 1.00 27.61 ? 209 PHE M CE1 1 ATOM 4996 C CE2 . PHE C 1 214 ? -10.992 65.485 17.949 1.00 29.39 ? 209 PHE M CE2 1 ATOM 4997 C CZ . PHE C 1 214 ? -11.695 64.575 17.194 1.00 28.39 ? 209 PHE M CZ 1 ATOM 4998 N N . ASN C 1 215 ? -10.665 70.239 16.469 1.00 25.05 ? 210 ASN M N 1 ATOM 4999 C CA . ASN C 1 215 ? -9.283 70.405 16.085 1.00 34.45 ? 210 ASN M CA 1 ATOM 5000 C C . ASN C 1 215 ? -8.485 69.805 17.231 1.00 33.85 ? 210 ASN M C 1 ATOM 5001 O O . ASN C 1 215 ? -8.651 70.146 18.409 1.00 29.50 ? 210 ASN M O 1 ATOM 5002 C CB . ASN C 1 215 ? -9.008 71.891 15.919 1.00 46.17 ? 210 ASN M CB 1 ATOM 5003 C CG . ASN C 1 215 ? -7.599 72.239 15.481 1.00 55.39 ? 210 ASN M CG 1 ATOM 5004 O OD1 . ASN C 1 215 ? -7.411 72.831 14.419 1.00 55.83 ? 210 ASN M OD1 1 ATOM 5005 N ND2 . ASN C 1 215 ? -6.554 71.945 16.264 1.00 63.13 ? 210 ASN M ND2 1 ATOM 5006 N N . ARG C 1 216 ? -7.520 69.005 16.846 1.00 33.85 ? 211 ARG M N 1 ATOM 5007 C CA . ARG C 1 216 ? -6.807 68.127 17.728 1.00 35.45 ? 211 ARG M CA 1 ATOM 5008 C C . ARG C 1 216 ? -6.172 68.560 19.005 1.00 37.54 ? 211 ARG M C 1 ATOM 5009 O O . ARG C 1 216 ? -5.682 67.689 19.704 1.00 38.97 ? 211 ARG M O 1 ATOM 5010 C CB . ARG C 1 216 ? -5.760 67.443 16.927 1.00 37.58 ? 211 ARG M CB 1 ATOM 5011 C CG . ARG C 1 216 ? -6.033 65.975 16.847 1.00 38.05 ? 211 ARG M CG 1 ATOM 5012 C CD . ARG C 1 216 ? -5.028 65.219 17.694 1.00 32.49 ? 211 ARG M CD 1 ATOM 5013 N NE . ARG C 1 216 ? -3.820 65.125 16.934 1.00 29.35 ? 211 ARG M NE 1 ATOM 5014 C CZ . ARG C 1 216 ? -2.684 65.581 17.410 1.00 29.31 ? 211 ARG M CZ 1 ATOM 5015 N NH1 . ARG C 1 216 ? -2.539 66.008 18.658 1.00 26.44 ? 211 ARG M NH1 1 ATOM 5016 N NH2 . ARG C 1 216 ? -1.654 65.542 16.600 1.00 32.56 ? 211 ARG M NH2 1 ATOM 5017 N N . ASN C 1 217 ? -6.154 69.783 19.465 1.00 51.33 ? 212 ASN M N 1 ATOM 5018 C CA . ASN C 1 217 ? -5.431 70.045 20.704 1.00 64.73 ? 212 ASN M CA 1 ATOM 5019 C C . ASN C 1 217 ? -6.188 70.906 21.702 1.00 72.74 ? 212 ASN M C 1 ATOM 5020 O O . ASN C 1 217 ? -6.623 72.025 21.393 1.00 73.22 ? 212 ASN M O 1 ATOM 5021 C CB . ASN C 1 217 ? -4.068 70.665 20.357 1.00 60.43 ? 212 ASN M CB 1 ATOM 5022 C CG . ASN C 1 217 ? -4.113 71.484 19.084 1.00 61.56 ? 212 ASN M CG 1 ATOM 5023 O OD1 . ASN C 1 217 ? -4.249 70.960 17.980 1.00 52.71 ? 212 ASN M OD1 1 ATOM 5024 N ND2 . ASN C 1 217 ? -4.087 72.799 19.202 1.00 67.65 ? 212 ASN M ND2 1 ATOM 5025 N N . GLU C 1 218 ? -6.422 70.252 22.863 1.00 77.71 ? 213 GLU M N 1 ATOM 5026 C CA . GLU C 1 218 ? -7.052 70.847 24.040 1.00 79.77 ? 213 GLU M CA 1 ATOM 5027 C C . GLU C 1 218 ? -5.970 71.735 24.646 1.00 84.27 ? 213 GLU M C 1 ATOM 5028 O O . GLU C 1 218 ? -4.859 71.297 24.974 1.00 84.00 ? 213 GLU M O 1 ATOM 5029 C CB . GLU C 1 218 ? -7.482 69.747 25.039 1.00 75.41 ? 213 GLU M CB 1 ATOM 5030 C CG . GLU C 1 218 ? -7.531 70.063 26.566 1.00 77.50 ? 213 GLU M CG 1 ATOM 5031 C CD . GLU C 1 218 ? -8.774 70.703 27.197 1.00 78.98 ? 213 GLU M CD 1 ATOM 5032 O OE1 . GLU C 1 218 ? -9.451 71.494 26.538 1.00 81.10 ? 213 GLU M OE1 1 ATOM 5033 O OE2 . GLU C 1 218 ? -9.060 70.409 28.367 1.00 74.35 ? 213 GLU M OE2 1 ATOM 5034 N N . CYS C 1 219 ? -6.358 72.997 24.681 1.00 88.09 ? 214 CYS M N 1 ATOM 5035 C CA . CYS C 1 219 ? -5.564 74.114 25.141 1.00 89.41 ? 214 CYS M CA 1 ATOM 5036 C C . CYS C 1 219 ? -6.620 75.166 25.567 1.00 89.99 ? 214 CYS M C 1 ATOM 5037 O O . CYS C 1 219 ? -7.780 74.794 25.805 1.00 87.93 ? 214 CYS M O 1 ATOM 5038 C CB . CYS C 1 219 ? -4.685 74.640 23.971 1.00 89.96 ? 214 CYS M CB 1 ATOM 5039 S SG . CYS C 1 219 ? -3.685 73.494 22.965 1.00 85.63 ? 214 CYS M SG 1 ATOM 5040 O OXT . CYS C 1 219 ? -6.297 76.356 25.653 1.00 89.55 ? 214 CYS M OXT 1 ATOM 5041 N N . GLU D 2 1 ? -51.656 29.677 29.790 1.00 74.73 ? 1 GLU J N 1 ATOM 5042 C CA . GLU D 2 1 ? -51.089 30.861 29.170 1.00 69.33 ? 1 GLU J CA 1 ATOM 5043 C C . GLU D 2 1 ? -49.854 30.227 28.509 1.00 63.25 ? 1 GLU J C 1 ATOM 5044 O O . GLU D 2 1 ? -49.080 29.645 29.268 1.00 63.73 ? 1 GLU J O 1 ATOM 5045 C CB . GLU D 2 1 ? -50.778 31.887 30.306 1.00 75.60 ? 1 GLU J CB 1 ATOM 5046 C CG . GLU D 2 1 ? -49.931 31.532 31.576 1.00 84.66 ? 1 GLU J CG 1 ATOM 5047 C CD . GLU D 2 1 ? -50.462 30.544 32.641 1.00 87.86 ? 1 GLU J CD 1 ATOM 5048 O OE1 . GLU D 2 1 ? -51.509 30.802 33.248 1.00 86.74 ? 1 GLU J OE1 1 ATOM 5049 O OE2 . GLU D 2 1 ? -49.799 29.528 32.890 1.00 89.27 ? 1 GLU J OE2 1 ATOM 5050 N N . VAL D 2 2 ? -49.686 30.190 27.173 1.00 50.15 ? 2 VAL J N 1 ATOM 5051 C CA . VAL D 2 2 ? -48.586 29.449 26.566 1.00 40.41 ? 2 VAL J CA 1 ATOM 5052 C C . VAL D 2 2 ? -47.296 30.100 27.014 1.00 39.34 ? 2 VAL J C 1 ATOM 5053 O O . VAL D 2 2 ? -47.199 31.310 26.828 1.00 47.74 ? 2 VAL J O 1 ATOM 5054 C CB . VAL D 2 2 ? -48.684 29.495 25.024 1.00 37.57 ? 2 VAL J CB 1 ATOM 5055 C CG1 . VAL D 2 2 ? -47.478 28.825 24.382 1.00 34.36 ? 2 VAL J CG1 1 ATOM 5056 C CG2 . VAL D 2 2 ? -49.906 28.742 24.568 1.00 35.98 ? 2 VAL J CG2 1 ATOM 5057 N N . GLN D 2 3 ? -46.341 29.430 27.641 1.00 35.84 ? 3 GLN J N 1 ATOM 5058 C CA . GLN D 2 3 ? -45.078 30.050 28.001 1.00 33.97 ? 3 GLN J CA 1 ATOM 5059 C C . GLN D 2 3 ? -44.022 29.063 27.511 1.00 30.44 ? 3 GLN J C 1 ATOM 5060 O O . GLN D 2 3 ? -44.209 27.842 27.611 1.00 36.34 ? 3 GLN J O 1 ATOM 5061 C CB . GLN D 2 3 ? -45.007 30.237 29.508 1.00 37.29 ? 3 GLN J CB 1 ATOM 5062 C CG . GLN D 2 3 ? -44.845 31.680 29.975 1.00 41.11 ? 3 GLN J CG 1 ATOM 5063 C CD . GLN D 2 3 ? -43.707 31.818 30.992 1.00 50.23 ? 3 GLN J CD 1 ATOM 5064 O OE1 . GLN D 2 3 ? -42.702 32.490 30.728 1.00 54.91 ? 3 GLN J OE1 1 ATOM 5065 N NE2 . GLN D 2 3 ? -43.751 31.202 32.175 1.00 45.91 ? 3 GLN J NE2 1 ATOM 5066 N N . LEU D 2 4 ? -42.934 29.519 26.897 1.00 19.73 ? 4 LEU J N 1 ATOM 5067 C CA . LEU D 2 4 ? -41.946 28.614 26.335 1.00 17.19 ? 4 LEU J CA 1 ATOM 5068 C C . LEU D 2 4 ? -40.630 29.301 26.544 1.00 17.96 ? 4 LEU J C 1 ATOM 5069 O O . LEU D 2 4 ? -40.445 30.431 26.069 1.00 23.39 ? 4 LEU J O 1 ATOM 5070 C CB . LEU D 2 4 ? -42.152 28.413 24.847 1.00 12.08 ? 4 LEU J CB 1 ATOM 5071 C CG . LEU D 2 4 ? -43.398 27.676 24.417 1.00 11.84 ? 4 LEU J CG 1 ATOM 5072 C CD1 . LEU D 2 4 ? -43.731 27.965 22.950 1.00 11.40 ? 4 LEU J CD1 1 ATOM 5073 C CD2 . LEU D 2 4 ? -43.170 26.221 24.739 1.00 11.74 ? 4 LEU J CD2 1 ATOM 5074 N N . VAL D 2 5 ? -39.705 28.695 27.279 1.00 7.77 ? 5 VAL J N 1 ATOM 5075 C CA . VAL D 2 5 ? -38.503 29.400 27.591 1.00 3.19 ? 5 VAL J CA 1 ATOM 5076 C C . VAL D 2 5 ? -37.291 28.558 27.313 1.00 6.90 ? 5 VAL J C 1 ATOM 5077 O O . VAL D 2 5 ? -37.177 27.447 27.849 1.00 15.03 ? 5 VAL J O 1 ATOM 5078 C CB . VAL D 2 5 ? -38.640 29.802 29.046 1.00 5.58 ? 5 VAL J CB 1 ATOM 5079 C CG1 . VAL D 2 5 ? -37.390 30.518 29.500 1.00 12.03 ? 5 VAL J CG1 1 ATOM 5080 C CG2 . VAL D 2 5 ? -39.786 30.797 29.205 1.00 8.15 ? 5 VAL J CG2 1 ATOM 5081 N N . GLU D 2 6 ? -36.343 29.117 26.563 1.00 2.00 ? 6 GLU J N 1 ATOM 5082 C CA . GLU D 2 6 ? -35.185 28.358 26.107 1.00 7.65 ? 6 GLU J CA 1 ATOM 5083 C C . GLU D 2 6 ? -33.936 28.660 26.919 1.00 6.74 ? 6 GLU J C 1 ATOM 5084 O O . GLU D 2 6 ? -33.857 29.731 27.526 1.00 5.38 ? 6 GLU J O 1 ATOM 5085 C CB . GLU D 2 6 ? -34.853 28.659 24.658 1.00 10.28 ? 6 GLU J CB 1 ATOM 5086 C CG . GLU D 2 6 ? -35.933 28.465 23.608 1.00 13.46 ? 6 GLU J CG 1 ATOM 5087 C CD . GLU D 2 6 ? -36.901 29.608 23.437 1.00 13.76 ? 6 GLU J CD 1 ATOM 5088 O OE1 . GLU D 2 6 ? -37.300 30.240 24.409 1.00 6.76 ? 6 GLU J OE1 1 ATOM 5089 O OE2 . GLU D 2 6 ? -37.250 29.873 22.292 1.00 18.97 ? 6 GLU J OE2 1 ATOM 5090 N N . SER D 2 7 ? -32.929 27.786 26.938 1.00 8.11 ? 7 SER J N 1 ATOM 5091 C CA . SER D 2 7 ? -31.737 27.976 27.753 1.00 2.22 ? 7 SER J CA 1 ATOM 5092 C C . SER D 2 7 ? -30.543 27.255 27.162 1.00 4.08 ? 7 SER J C 1 ATOM 5093 O O . SER D 2 7 ? -30.706 26.376 26.333 1.00 10.65 ? 7 SER J O 1 ATOM 5094 C CB . SER D 2 7 ? -31.968 27.432 29.142 1.00 4.16 ? 7 SER J CB 1 ATOM 5095 O OG . SER D 2 7 ? -33.240 26.775 29.270 1.00 19.63 ? 7 SER J OG 1 ATOM 5096 N N . GLY D 2 8 ? -29.300 27.615 27.467 1.00 12.22 ? 8 GLY J N 1 ATOM 5097 C CA . GLY D 2 8 ? -28.159 26.822 27.063 1.00 5.96 ? 8 GLY J CA 1 ATOM 5098 C C . GLY D 2 8 ? -27.484 27.275 25.811 1.00 10.45 ? 8 GLY J C 1 ATOM 5099 O O . GLY D 2 8 ? -26.497 26.625 25.468 1.00 10.12 ? 8 GLY J O 1 ATOM 5100 N N . GLY D 2 9 ? -27.956 28.323 25.104 1.00 13.29 ? 9 GLY J N 1 ATOM 5101 C CA . GLY D 2 9 ? -27.184 28.862 23.977 1.00 17.23 ? 9 GLY J CA 1 ATOM 5102 C C . GLY D 2 9 ? -25.820 29.326 24.509 1.00 22.46 ? 9 GLY J C 1 ATOM 5103 O O . GLY D 2 9 ? -25.787 29.786 25.665 1.00 26.68 ? 9 GLY J O 1 ATOM 5104 N N . ASP D 2 10 ? -24.684 29.252 23.818 1.00 19.86 ? 10 ASP J N 1 ATOM 5105 C CA . ASP D 2 10 ? -23.438 29.616 24.484 1.00 21.19 ? 10 ASP J CA 1 ATOM 5106 C C . ASP D 2 10 ? -22.386 29.743 23.424 1.00 18.88 ? 10 ASP J C 1 ATOM 5107 O O . ASP D 2 10 ? -22.737 29.644 22.250 1.00 29.43 ? 10 ASP J O 1 ATOM 5108 C CB . ASP D 2 10 ? -23.018 28.542 25.448 1.00 23.59 ? 10 ASP J CB 1 ATOM 5109 C CG . ASP D 2 10 ? -22.247 28.997 26.675 1.00 35.33 ? 10 ASP J CG 1 ATOM 5110 O OD1 . ASP D 2 10 ? -21.383 29.880 26.630 1.00 38.98 ? 10 ASP J OD1 1 ATOM 5111 O OD2 . ASP D 2 10 ? -22.504 28.404 27.718 1.00 45.35 ? 10 ASP J OD2 1 ATOM 5112 N N . LEU D 2 11 ? -21.121 29.960 23.757 1.00 13.01 ? 11 LEU J N 1 ATOM 5113 C CA . LEU D 2 11 ? -20.092 30.067 22.757 1.00 15.56 ? 11 LEU J CA 1 ATOM 5114 C C . LEU D 2 11 ? -19.467 28.681 22.669 1.00 22.73 ? 11 LEU J C 1 ATOM 5115 O O . LEU D 2 11 ? -19.067 28.057 23.673 1.00 18.40 ? 11 LEU J O 1 ATOM 5116 C CB . LEU D 2 11 ? -19.056 31.090 23.174 1.00 10.41 ? 11 LEU J CB 1 ATOM 5117 C CG . LEU D 2 11 ? -17.779 31.144 22.340 1.00 12.38 ? 11 LEU J CG 1 ATOM 5118 C CD1 . LEU D 2 11 ? -18.097 31.455 20.891 1.00 12.32 ? 11 LEU J CD1 1 ATOM 5119 C CD2 . LEU D 2 11 ? -16.848 32.184 22.937 1.00 16.00 ? 11 LEU J CD2 1 ATOM 5120 N N . VAL D 2 12 ? -19.439 28.255 21.407 1.00 22.78 ? 12 VAL J N 1 ATOM 5121 C CA . VAL D 2 12 ? -18.966 26.946 21.024 1.00 25.37 ? 12 VAL J CA 1 ATOM 5122 C C . VAL D 2 12 ? -17.921 27.077 19.911 1.00 27.94 ? 12 VAL J C 1 ATOM 5123 O O . VAL D 2 12 ? -18.116 27.821 18.944 1.00 31.32 ? 12 VAL J O 1 ATOM 5124 C CB . VAL D 2 12 ? -20.171 26.094 20.525 1.00 29.82 ? 12 VAL J CB 1 ATOM 5125 C CG1 . VAL D 2 12 ? -19.721 24.650 20.426 1.00 33.57 ? 12 VAL J CG1 1 ATOM 5126 C CG2 . VAL D 2 12 ? -21.353 26.140 21.468 1.00 27.59 ? 12 VAL J CG2 1 ATOM 5127 N N . LYS D 2 13 ? -16.817 26.338 19.985 1.00 25.52 ? 13 LYS J N 1 ATOM 5128 C CA . LYS D 2 13 ? -15.785 26.349 18.957 1.00 26.36 ? 13 LYS J CA 1 ATOM 5129 C C . LYS D 2 13 ? -16.294 25.530 17.782 1.00 30.80 ? 13 LYS J C 1 ATOM 5130 O O . LYS D 2 13 ? -16.929 24.502 18.025 1.00 36.04 ? 13 LYS J O 1 ATOM 5131 C CB . LYS D 2 13 ? -14.541 25.729 19.531 1.00 28.27 ? 13 LYS J CB 1 ATOM 5132 C CG . LYS D 2 13 ? -14.048 26.582 20.688 1.00 40.59 ? 13 LYS J CG 1 ATOM 5133 C CD . LYS D 2 13 ? -13.394 27.898 20.216 1.00 44.00 ? 13 LYS J CD 1 ATOM 5134 C CE . LYS D 2 13 ? -13.304 29.010 21.270 1.00 40.24 ? 13 LYS J CE 1 ATOM 5135 N NZ . LYS D 2 13 ? -14.478 29.860 21.219 1.00 32.51 ? 13 LYS J NZ 1 ATOM 5136 N N . PRO D 2 14 ? -16.103 25.851 16.513 1.00 32.00 ? 14 PRO J N 1 ATOM 5137 C CA . PRO D 2 14 ? -16.762 25.172 15.415 1.00 33.77 ? 14 PRO J CA 1 ATOM 5138 C C . PRO D 2 14 ? -16.320 23.728 15.307 1.00 39.61 ? 14 PRO J C 1 ATOM 5139 O O . PRO D 2 14 ? -15.218 23.425 14.854 1.00 49.27 ? 14 PRO J O 1 ATOM 5140 C CB . PRO D 2 14 ? -16.418 26.032 14.229 1.00 31.93 ? 14 PRO J CB 1 ATOM 5141 C CG . PRO D 2 14 ? -15.048 26.539 14.551 1.00 30.36 ? 14 PRO J CG 1 ATOM 5142 C CD . PRO D 2 14 ? -15.146 26.829 16.042 1.00 33.42 ? 14 PRO J CD 1 ATOM 5143 N N . GLY D 2 15 ? -17.193 22.841 15.760 1.00 41.32 ? 15 GLY J N 1 ATOM 5144 C CA . GLY D 2 15 ? -16.921 21.420 15.803 1.00 39.92 ? 15 GLY J CA 1 ATOM 5145 C C . GLY D 2 15 ? -17.537 20.834 17.058 1.00 40.37 ? 15 GLY J C 1 ATOM 5146 O O . GLY D 2 15 ? -17.806 19.638 17.132 1.00 45.79 ? 15 GLY J O 1 ATOM 5147 N N . GLY D 2 16 ? -17.834 21.660 18.056 1.00 34.51 ? 16 GLY J N 1 ATOM 5148 C CA . GLY D 2 16 ? -18.407 21.198 19.304 1.00 28.04 ? 16 GLY J CA 1 ATOM 5149 C C . GLY D 2 16 ? -19.831 20.658 19.261 1.00 26.98 ? 16 GLY J C 1 ATOM 5150 O O . GLY D 2 16 ? -20.481 20.403 18.230 1.00 20.43 ? 16 GLY J O 1 ATOM 5151 N N . SER D 2 17 ? -20.267 20.546 20.512 1.00 28.37 ? 17 SER J N 1 ATOM 5152 C CA . SER D 2 17 ? -21.554 19.982 20.831 1.00 33.30 ? 17 SER J CA 1 ATOM 5153 C C . SER D 2 17 ? -22.233 20.788 21.937 1.00 33.90 ? 17 SER J C 1 ATOM 5154 O O . SER D 2 17 ? -21.556 21.187 22.899 1.00 35.60 ? 17 SER J O 1 ATOM 5155 C CB . SER D 2 17 ? -21.333 18.544 21.276 1.00 39.33 ? 17 SER J CB 1 ATOM 5156 O OG . SER D 2 17 ? -20.441 17.811 20.429 1.00 50.38 ? 17 SER J OG 1 ATOM 5157 N N . LEU D 2 18 ? -23.545 21.025 21.834 1.00 30.37 ? 18 LEU J N 1 ATOM 5158 C CA . LEU D 2 18 ? -24.299 21.766 22.833 1.00 28.42 ? 18 LEU J CA 1 ATOM 5159 C C . LEU D 2 18 ? -25.756 21.315 22.849 1.00 28.22 ? 18 LEU J C 1 ATOM 5160 O O . LEU D 2 18 ? -26.295 20.985 21.793 1.00 27.29 ? 18 LEU J O 1 ATOM 5161 C CB . LEU D 2 18 ? -24.314 23.244 22.529 1.00 26.43 ? 18 LEU J CB 1 ATOM 5162 C CG . LEU D 2 18 ? -24.047 24.242 23.641 1.00 27.47 ? 18 LEU J CG 1 ATOM 5163 C CD1 . LEU D 2 18 ? -24.520 25.577 23.129 1.00 31.94 ? 18 LEU J CD1 1 ATOM 5164 C CD2 . LEU D 2 18 ? -24.810 23.951 24.922 1.00 33.96 ? 18 LEU J CD2 1 ATOM 5165 N N . LYS D 2 19 ? -26.436 21.310 23.992 1.00 24.37 ? 19 LYS J N 1 ATOM 5166 C CA . LYS D 2 19 ? -27.838 20.976 24.040 1.00 21.37 ? 19 LYS J CA 1 ATOM 5167 C C . LYS D 2 19 ? -28.625 22.139 24.633 1.00 21.64 ? 19 LYS J C 1 ATOM 5168 O O . LYS D 2 19 ? -28.380 22.603 25.764 1.00 23.82 ? 19 LYS J O 1 ATOM 5169 C CB . LYS D 2 19 ? -27.984 19.753 24.873 1.00 29.02 ? 19 LYS J CB 1 ATOM 5170 C CG . LYS D 2 19 ? -29.391 19.433 25.307 1.00 32.10 ? 19 LYS J CG 1 ATOM 5171 C CD . LYS D 2 19 ? -29.101 18.659 26.564 1.00 37.14 ? 19 LYS J CD 1 ATOM 5172 C CE . LYS D 2 19 ? -30.246 18.803 27.539 1.00 47.04 ? 19 LYS J CE 1 ATOM 5173 N NZ . LYS D 2 19 ? -31.412 18.009 27.164 1.00 52.50 ? 19 LYS J NZ 1 ATOM 5174 N N . LEU D 2 20 ? -29.587 22.586 23.839 1.00 13.27 ? 20 LEU J N 1 ATOM 5175 C CA . LEU D 2 20 ? -30.440 23.713 24.176 1.00 6.00 ? 20 LEU J CA 1 ATOM 5176 C C . LEU D 2 20 ? -31.729 23.146 24.758 1.00 11.29 ? 20 LEU J C 1 ATOM 5177 O O . LEU D 2 20 ? -32.316 22.275 24.106 1.00 14.83 ? 20 LEU J O 1 ATOM 5178 C CB . LEU D 2 20 ? -30.754 24.473 22.925 1.00 2.00 ? 20 LEU J CB 1 ATOM 5179 C CG . LEU D 2 20 ? -29.984 25.656 22.302 1.00 6.61 ? 20 LEU J CG 1 ATOM 5180 C CD1 . LEU D 2 20 ? -28.448 25.748 22.478 1.00 2.00 ? 20 LEU J CD1 1 ATOM 5181 C CD2 . LEU D 2 20 ? -30.383 25.480 20.856 1.00 2.00 ? 20 LEU J CD2 1 ATOM 5182 N N . SER D 2 21 ? -32.213 23.478 25.950 1.00 14.43 ? 21 SER J N 1 ATOM 5183 C CA . SER D 2 21 ? -33.508 22.970 26.357 1.00 20.51 ? 21 SER J CA 1 ATOM 5184 C C . SER D 2 21 ? -34.568 24.073 26.240 1.00 23.89 ? 21 SER J C 1 ATOM 5185 O O . SER D 2 21 ? -34.273 25.251 25.968 1.00 20.66 ? 21 SER J O 1 ATOM 5186 C CB . SER D 2 21 ? -33.431 22.413 27.791 1.00 29.80 ? 21 SER J CB 1 ATOM 5187 O OG . SER D 2 21 ? -32.359 22.809 28.654 1.00 41.75 ? 21 SER J OG 1 ATOM 5188 N N . CYS D 2 22 ? -35.833 23.691 26.368 1.00 21.16 ? 22 CYS J N 1 ATOM 5189 C CA . CYS D 2 22 ? -36.925 24.613 26.173 1.00 19.02 ? 22 CYS J CA 1 ATOM 5190 C C . CYS D 2 22 ? -38.012 24.086 27.084 1.00 19.79 ? 22 CYS J C 1 ATOM 5191 O O . CYS D 2 22 ? -38.452 22.942 26.900 1.00 16.67 ? 22 CYS J O 1 ATOM 5192 C CB . CYS D 2 22 ? -37.335 24.588 24.689 1.00 9.66 ? 22 CYS J CB 1 ATOM 5193 S SG . CYS D 2 22 ? -39.102 24.909 24.471 1.00 7.33 ? 22 CYS J SG 1 ATOM 5194 N N . ALA D 2 23 ? -38.377 24.859 28.117 1.00 21.75 ? 23 ALA J N 1 ATOM 5195 C CA . ALA D 2 23 ? -39.416 24.447 29.057 1.00 22.17 ? 23 ALA J CA 1 ATOM 5196 C C . ALA D 2 23 ? -40.763 25.069 28.741 1.00 22.77 ? 23 ALA J C 1 ATOM 5197 O O . ALA D 2 23 ? -40.891 26.301 28.645 1.00 20.97 ? 23 ALA J O 1 ATOM 5198 C CB . ALA D 2 23 ? -39.063 24.843 30.463 1.00 23.91 ? 23 ALA J CB 1 ATOM 5199 N N . ALA D 2 24 ? -41.744 24.180 28.565 1.00 20.81 ? 24 ALA J N 1 ATOM 5200 C CA . ALA D 2 24 ? -43.054 24.590 28.104 1.00 19.13 ? 24 ALA J CA 1 ATOM 5201 C C . ALA D 2 24 ? -43.924 24.620 29.312 1.00 20.44 ? 24 ALA J C 1 ATOM 5202 O O . ALA D 2 24 ? -43.611 23.899 30.260 1.00 18.42 ? 24 ALA J O 1 ATOM 5203 C CB . ALA D 2 24 ? -43.622 23.586 27.148 1.00 19.59 ? 24 ALA J CB 1 ATOM 5204 N N . SER D 2 25 ? -44.968 25.436 29.316 1.00 23.68 ? 25 SER J N 1 ATOM 5205 C CA . SER D 2 25 ? -45.867 25.493 30.444 1.00 27.80 ? 25 SER J CA 1 ATOM 5206 C C . SER D 2 25 ? -47.044 26.335 30.061 1.00 27.96 ? 25 SER J C 1 ATOM 5207 O O . SER D 2 25 ? -47.058 27.009 29.037 1.00 29.49 ? 25 SER J O 1 ATOM 5208 C CB . SER D 2 25 ? -45.225 26.117 31.696 1.00 26.65 ? 25 SER J CB 1 ATOM 5209 O OG . SER D 2 25 ? -45.138 27.535 31.722 1.00 31.37 ? 25 SER J OG 1 ATOM 5210 N N . GLY D 2 26 ? -48.075 26.212 30.881 1.00 33.07 ? 26 GLY J N 1 ATOM 5211 C CA . GLY D 2 26 ? -49.288 26.960 30.685 1.00 33.11 ? 26 GLY J CA 1 ATOM 5212 C C . GLY D 2 26 ? -50.232 26.373 29.657 1.00 33.22 ? 26 GLY J C 1 ATOM 5213 O O . GLY D 2 26 ? -51.238 27.053 29.391 1.00 34.03 ? 26 GLY J O 1 ATOM 5214 N N . PHE D 2 27 ? -49.939 25.198 29.075 1.00 36.81 ? 27 PHE J N 1 ATOM 5215 C CA . PHE D 2 27 ? -50.823 24.445 28.166 1.00 35.94 ? 27 PHE J CA 1 ATOM 5216 C C . PHE D 2 27 ? -50.518 22.968 28.408 1.00 35.27 ? 27 PHE J C 1 ATOM 5217 O O . PHE D 2 27 ? -49.670 22.675 29.266 1.00 28.62 ? 27 PHE J O 1 ATOM 5218 C CB . PHE D 2 27 ? -50.578 24.764 26.667 1.00 32.54 ? 27 PHE J CB 1 ATOM 5219 C CG . PHE D 2 27 ? -49.233 24.333 26.097 1.00 30.29 ? 27 PHE J CG 1 ATOM 5220 C CD1 . PHE D 2 27 ? -48.053 24.660 26.724 1.00 29.14 ? 27 PHE J CD1 1 ATOM 5221 C CD2 . PHE D 2 27 ? -49.212 23.574 24.951 1.00 31.19 ? 27 PHE J CD2 1 ATOM 5222 C CE1 . PHE D 2 27 ? -46.870 24.214 26.195 1.00 31.98 ? 27 PHE J CE1 1 ATOM 5223 C CE2 . PHE D 2 27 ? -48.022 23.133 24.433 1.00 29.36 ? 27 PHE J CE2 1 ATOM 5224 C CZ . PHE D 2 27 ? -46.849 23.451 25.052 1.00 30.09 ? 27 PHE J CZ 1 ATOM 5225 N N . THR D 2 28 ? -51.158 22.037 27.686 1.00 40.71 ? 28 THR J N 1 ATOM 5226 C CA . THR D 2 28 ? -50.948 20.594 27.869 1.00 44.55 ? 28 THR J CA 1 ATOM 5227 C C . THR D 2 28 ? -50.004 20.100 26.795 1.00 43.03 ? 28 THR J C 1 ATOM 5228 O O . THR D 2 28 ? -50.291 20.207 25.597 1.00 43.13 ? 28 THR J O 1 ATOM 5229 C CB . THR D 2 28 ? -52.270 19.870 27.765 1.00 48.19 ? 28 THR J CB 1 ATOM 5230 O OG1 . THR D 2 28 ? -53.068 20.572 26.808 1.00 54.15 ? 28 THR J OG1 1 ATOM 5231 C CG2 . THR D 2 28 ? -52.926 19.767 29.135 1.00 53.22 ? 28 THR J CG2 1 ATOM 5232 N N . PHE D 2 29 ? -48.876 19.546 27.243 1.00 39.21 ? 29 PHE J N 1 ATOM 5233 C CA . PHE D 2 29 ? -47.739 19.292 26.355 1.00 36.74 ? 29 PHE J CA 1 ATOM 5234 C C . PHE D 2 29 ? -47.915 18.250 25.239 1.00 34.81 ? 29 PHE J C 1 ATOM 5235 O O . PHE D 2 29 ? -47.792 18.380 24.017 1.00 26.42 ? 29 PHE J O 1 ATOM 5236 C CB . PHE D 2 29 ? -46.591 18.960 27.322 1.00 33.29 ? 29 PHE J CB 1 ATOM 5237 C CG . PHE D 2 29 ? -45.195 19.183 26.776 1.00 32.89 ? 29 PHE J CG 1 ATOM 5238 C CD1 . PHE D 2 29 ? -44.968 19.999 25.685 1.00 33.56 ? 29 PHE J CD1 1 ATOM 5239 C CD2 . PHE D 2 29 ? -44.151 18.534 27.377 1.00 33.17 ? 29 PHE J CD2 1 ATOM 5240 C CE1 . PHE D 2 29 ? -43.697 20.152 25.197 1.00 31.65 ? 29 PHE J CE1 1 ATOM 5241 C CE2 . PHE D 2 29 ? -42.883 18.697 26.880 1.00 32.91 ? 29 PHE J CE2 1 ATOM 5242 C CZ . PHE D 2 29 ? -42.656 19.499 25.798 1.00 31.33 ? 29 PHE J CZ 1 ATOM 5243 N N . SER D 2 30 ? -48.342 17.173 25.816 1.00 34.40 ? 30 SER J N 1 ATOM 5244 C CA . SER D 2 30 ? -48.622 15.917 25.203 1.00 35.30 ? 30 SER J CA 1 ATOM 5245 C C . SER D 2 30 ? -49.941 16.035 24.492 1.00 35.09 ? 30 SER J C 1 ATOM 5246 O O . SER D 2 30 ? -50.911 15.424 24.917 1.00 44.80 ? 30 SER J O 1 ATOM 5247 C CB . SER D 2 30 ? -48.634 14.980 26.364 1.00 42.53 ? 30 SER J CB 1 ATOM 5248 O OG . SER D 2 30 ? -49.277 15.652 27.464 1.00 52.62 ? 30 SER J OG 1 ATOM 5249 N N . ARG D 2 31 ? -50.020 16.830 23.465 1.00 30.82 ? 31 ARG J N 1 ATOM 5250 C CA . ARG D 2 31 ? -51.226 17.077 22.690 1.00 33.47 ? 31 ARG J CA 1 ATOM 5251 C C . ARG D 2 31 ? -50.715 18.007 21.607 1.00 38.74 ? 31 ARG J C 1 ATOM 5252 O O . ARG D 2 31 ? -51.285 18.108 20.512 1.00 47.22 ? 31 ARG J O 1 ATOM 5253 C CB . ARG D 2 31 ? -52.321 17.851 23.413 1.00 38.70 ? 31 ARG J CB 1 ATOM 5254 C CG . ARG D 2 31 ? -53.159 17.174 24.489 1.00 52.99 ? 31 ARG J CG 1 ATOM 5255 C CD . ARG D 2 31 ? -54.669 17.003 24.220 1.00 64.05 ? 31 ARG J CD 1 ATOM 5256 N NE . ARG D 2 31 ? -55.099 16.331 22.987 1.00 71.80 ? 31 ARG J NE 1 ATOM 5257 C CZ . ARG D 2 31 ? -54.782 15.079 22.613 1.00 73.81 ? 31 ARG J CZ 1 ATOM 5258 N NH1 . ARG D 2 31 ? -53.930 14.292 23.286 1.00 72.98 ? 31 ARG J NH1 1 ATOM 5259 N NH2 . ARG D 2 31 ? -55.325 14.627 21.486 1.00 74.83 ? 31 ARG J NH2 1 ATOM 5260 N N . CYS D 2 32 ? -49.624 18.722 21.916 1.00 32.80 ? 32 CYS J N 1 ATOM 5261 C CA . CYS D 2 32 ? -48.989 19.613 20.996 1.00 24.30 ? 32 CYS J CA 1 ATOM 5262 C C . CYS D 2 32 ? -47.583 19.112 20.612 1.00 25.92 ? 32 CYS J C 1 ATOM 5263 O O . CYS D 2 32 ? -46.786 18.585 21.414 1.00 19.78 ? 32 CYS J O 1 ATOM 5264 C CB . CYS D 2 32 ? -49.061 20.944 21.721 1.00 21.46 ? 32 CYS J CB 1 ATOM 5265 S SG . CYS D 2 32 ? -50.708 21.699 21.496 1.00 29.31 ? 32 CYS J SG 1 ATOM 5266 N N . ALA D 2 33 ? -47.368 19.074 19.291 1.00 20.28 ? 33 ALA J N 1 ATOM 5267 C CA . ALA D 2 33 ? -46.066 18.721 18.744 1.00 18.96 ? 33 ALA J CA 1 ATOM 5268 C C . ALA D 2 33 ? -45.141 19.939 18.848 1.00 26.20 ? 33 ALA J C 1 ATOM 5269 O O . ALA D 2 33 ? -45.616 21.085 18.926 1.00 31.03 ? 33 ALA J O 1 ATOM 5270 C CB . ALA D 2 33 ? -46.204 18.357 17.297 1.00 15.58 ? 33 ALA J CB 1 ATOM 5271 N N . MET D 2 34 ? -43.826 19.818 18.834 1.00 26.35 ? 34 MET J N 1 ATOM 5272 C CA . MET D 2 34 ? -43.020 21.011 18.950 1.00 25.01 ? 34 MET J CA 1 ATOM 5273 C C . MET D 2 34 ? -42.077 21.125 17.771 1.00 30.18 ? 34 MET J C 1 ATOM 5274 O O . MET D 2 34 ? -42.026 20.211 16.926 1.00 30.22 ? 34 MET J O 1 ATOM 5275 C CB . MET D 2 34 ? -42.263 20.967 20.254 1.00 21.34 ? 34 MET J CB 1 ATOM 5276 C CG . MET D 2 34 ? -43.205 21.001 21.462 1.00 23.22 ? 34 MET J CG 1 ATOM 5277 S SD . MET D 2 34 ? -44.416 22.355 21.574 1.00 15.22 ? 34 MET J SD 1 ATOM 5278 C CE . MET D 2 34 ? -43.674 22.906 23.065 1.00 20.57 ? 34 MET J CE 1 ATOM 5279 N N . SER D 2 35 ? -41.357 22.255 17.699 1.00 27.86 ? 35 SER J N 1 ATOM 5280 C CA . SER D 2 35 ? -40.440 22.563 16.620 1.00 17.01 ? 35 SER J CA 1 ATOM 5281 C C . SER D 2 35 ? -39.333 23.423 17.171 1.00 15.79 ? 35 SER J C 1 ATOM 5282 O O . SER D 2 35 ? -39.578 24.066 18.190 1.00 19.25 ? 35 SER J O 1 ATOM 5283 C CB . SER D 2 35 ? -41.183 23.317 15.584 1.00 12.99 ? 35 SER J CB 1 ATOM 5284 O OG . SER D 2 35 ? -40.366 23.810 14.541 1.00 18.94 ? 35 SER J OG 1 ATOM 5285 N N . TRP D 2 36 ? -38.144 23.458 16.561 1.00 9.67 ? 36 TRP J N 1 ATOM 5286 C CA . TRP D 2 36 ? -37.108 24.421 16.912 1.00 9.99 ? 36 TRP J CA 1 ATOM 5287 C C . TRP D 2 36 ? -36.897 25.210 15.627 1.00 14.90 ? 36 TRP J C 1 ATOM 5288 O O . TRP D 2 36 ? -37.040 24.603 14.563 1.00 20.55 ? 36 TRP J O 1 ATOM 5289 C CB . TRP D 2 36 ? -35.823 23.782 17.274 1.00 6.94 ? 36 TRP J CB 1 ATOM 5290 C CG . TRP D 2 36 ? -35.778 23.347 18.726 1.00 13.92 ? 36 TRP J CG 1 ATOM 5291 C CD1 . TRP D 2 36 ? -36.101 22.069 19.031 1.00 18.75 ? 36 TRP J CD1 1 ATOM 5292 C CD2 . TRP D 2 36 ? -35.328 24.043 19.838 1.00 17.81 ? 36 TRP J CD2 1 ATOM 5293 N NE1 . TRP D 2 36 ? -35.833 21.931 20.303 1.00 21.13 ? 36 TRP J NE1 1 ATOM 5294 C CE2 . TRP D 2 36 ? -35.377 23.074 20.817 1.00 19.40 ? 36 TRP J CE2 1 ATOM 5295 C CE3 . TRP D 2 36 ? -34.883 25.297 20.197 1.00 15.40 ? 36 TRP J CE3 1 ATOM 5296 C CZ2 . TRP D 2 36 ? -34.996 23.335 22.112 1.00 20.07 ? 36 TRP J CZ2 1 ATOM 5297 C CZ3 . TRP D 2 36 ? -34.503 25.559 21.487 1.00 11.14 ? 36 TRP J CZ3 1 ATOM 5298 C CH2 . TRP D 2 36 ? -34.557 24.589 22.445 1.00 14.55 ? 36 TRP J CH2 1 ATOM 5299 N N . VAL D 2 37 ? -36.616 26.523 15.596 1.00 15.69 ? 37 VAL J N 1 ATOM 5300 C CA . VAL D 2 37 ? -36.577 27.344 14.380 1.00 10.10 ? 37 VAL J CA 1 ATOM 5301 C C . VAL D 2 37 ? -35.475 28.378 14.595 1.00 10.49 ? 37 VAL J C 1 ATOM 5302 O O . VAL D 2 37 ? -35.220 28.769 15.734 1.00 15.41 ? 37 VAL J O 1 ATOM 5303 C CB . VAL D 2 37 ? -37.964 28.039 14.155 1.00 6.26 ? 37 VAL J CB 1 ATOM 5304 C CG1 . VAL D 2 37 ? -37.987 28.836 12.862 1.00 2.28 ? 37 VAL J CG1 1 ATOM 5305 C CG2 . VAL D 2 37 ? -39.069 27.007 13.965 1.00 7.40 ? 37 VAL J CG2 1 ATOM 5306 N N . ARG D 2 38 ? -34.809 28.844 13.547 1.00 10.76 ? 38 ARG J N 1 ATOM 5307 C CA . ARG D 2 38 ? -33.629 29.680 13.660 1.00 15.29 ? 38 ARG J CA 1 ATOM 5308 C C . ARG D 2 38 ? -33.812 31.022 13.014 1.00 22.96 ? 38 ARG J C 1 ATOM 5309 O O . ARG D 2 38 ? -34.499 31.108 11.989 1.00 25.75 ? 38 ARG J O 1 ATOM 5310 C CB . ARG D 2 38 ? -32.426 29.178 12.931 1.00 17.10 ? 38 ARG J CB 1 ATOM 5311 C CG . ARG D 2 38 ? -31.783 27.949 13.413 1.00 20.89 ? 38 ARG J CG 1 ATOM 5312 C CD . ARG D 2 38 ? -30.407 27.974 12.811 1.00 20.48 ? 38 ARG J CD 1 ATOM 5313 N NE . ARG D 2 38 ? -30.244 27.595 11.425 1.00 19.20 ? 38 ARG J NE 1 ATOM 5314 C CZ . ARG D 2 38 ? -29.289 26.695 11.164 1.00 23.22 ? 38 ARG J CZ 1 ATOM 5315 N NH1 . ARG D 2 38 ? -28.678 25.999 12.124 1.00 26.13 ? 38 ARG J NH1 1 ATOM 5316 N NH2 . ARG D 2 38 ? -28.953 26.407 9.923 1.00 26.21 ? 38 ARG J NH2 1 ATOM 5317 N N . GLN D 2 39 ? -33.090 32.004 13.559 1.00 21.87 ? 39 GLN J N 1 ATOM 5318 C CA . GLN D 2 39 ? -33.010 33.326 12.986 1.00 20.62 ? 39 GLN J CA 1 ATOM 5319 C C . GLN D 2 39 ? -31.516 33.573 12.924 1.00 22.12 ? 39 GLN J C 1 ATOM 5320 O O . GLN D 2 39 ? -30.814 33.675 13.936 1.00 17.60 ? 39 GLN J O 1 ATOM 5321 C CB . GLN D 2 39 ? -33.660 34.372 13.871 1.00 19.52 ? 39 GLN J CB 1 ATOM 5322 C CG . GLN D 2 39 ? -33.734 35.684 13.116 1.00 20.19 ? 39 GLN J CG 1 ATOM 5323 C CD . GLN D 2 39 ? -34.924 36.542 13.500 1.00 21.17 ? 39 GLN J CD 1 ATOM 5324 O OE1 . GLN D 2 39 ? -35.225 36.767 14.672 1.00 21.54 ? 39 GLN J OE1 1 ATOM 5325 N NE2 . GLN D 2 39 ? -35.651 37.051 12.526 1.00 18.64 ? 39 GLN J NE2 1 ATOM 5326 N N . THR D 2 40 ? -31.060 33.574 11.685 1.00 24.59 ? 40 THR J N 1 ATOM 5327 C CA . THR D 2 40 ? -29.670 33.785 11.357 1.00 27.47 ? 40 THR J CA 1 ATOM 5328 C C . THR D 2 40 ? -29.373 35.255 11.605 1.00 31.56 ? 40 THR J C 1 ATOM 5329 O O . THR D 2 40 ? -30.315 36.028 11.787 1.00 38.79 ? 40 THR J O 1 ATOM 5330 C CB . THR D 2 40 ? -29.439 33.422 9.867 1.00 31.65 ? 40 THR J CB 1 ATOM 5331 O OG1 . THR D 2 40 ? -30.119 34.358 9.036 1.00 36.63 ? 40 THR J OG1 1 ATOM 5332 C CG2 . THR D 2 40 ? -30.004 32.064 9.529 1.00 36.93 ? 40 THR J CG2 1 ATOM 5333 N N . PRO D 2 41 ? -28.142 35.754 11.553 1.00 32.67 ? 41 PRO J N 1 ATOM 5334 C CA . PRO D 2 41 ? -27.831 37.179 11.475 1.00 32.43 ? 41 PRO J CA 1 ATOM 5335 C C . PRO D 2 41 ? -28.437 38.037 10.378 1.00 34.05 ? 41 PRO J C 1 ATOM 5336 O O . PRO D 2 41 ? -28.670 39.231 10.619 1.00 30.00 ? 41 PRO J O 1 ATOM 5337 C CB . PRO D 2 41 ? -26.331 37.214 11.455 1.00 31.14 ? 41 PRO J CB 1 ATOM 5338 C CG . PRO D 2 41 ? -25.921 35.804 11.192 1.00 32.97 ? 41 PRO J CG 1 ATOM 5339 C CD . PRO D 2 41 ? -26.959 35.029 11.962 1.00 32.40 ? 41 PRO J CD 1 ATOM 5340 N N . GLU D 2 42 ? -28.746 37.506 9.185 1.00 37.34 ? 42 GLU J N 1 ATOM 5341 C CA . GLU D 2 42 ? -29.412 38.377 8.228 1.00 45.29 ? 42 GLU J CA 1 ATOM 5342 C C . GLU D 2 42 ? -30.925 38.247 8.390 1.00 41.53 ? 42 GLU J C 1 ATOM 5343 O O . GLU D 2 42 ? -31.702 38.375 7.443 1.00 43.64 ? 42 GLU J O 1 ATOM 5344 C CB . GLU D 2 42 ? -28.996 38.033 6.789 1.00 50.58 ? 42 GLU J CB 1 ATOM 5345 C CG . GLU D 2 42 ? -28.609 39.311 5.960 1.00 69.11 ? 42 GLU J CG 1 ATOM 5346 C CD . GLU D 2 42 ? -29.644 40.200 5.210 1.00 76.92 ? 42 GLU J CD 1 ATOM 5347 O OE1 . GLU D 2 42 ? -30.743 40.464 5.711 1.00 80.30 ? 42 GLU J OE1 1 ATOM 5348 O OE2 . GLU D 2 42 ? -29.329 40.665 4.106 1.00 77.83 ? 42 GLU J OE2 1 ATOM 5349 N N . LYS D 2 43 ? -31.356 37.972 9.618 1.00 36.09 ? 43 LYS J N 1 ATOM 5350 C CA . LYS D 2 43 ? -32.741 37.764 9.998 1.00 36.28 ? 43 LYS J CA 1 ATOM 5351 C C . LYS D 2 43 ? -33.542 36.772 9.172 1.00 27.82 ? 43 LYS J C 1 ATOM 5352 O O . LYS D 2 43 ? -34.761 36.818 9.257 1.00 27.10 ? 43 LYS J O 1 ATOM 5353 C CB . LYS D 2 43 ? -33.455 39.139 10.036 1.00 43.85 ? 43 LYS J CB 1 ATOM 5354 C CG . LYS D 2 43 ? -32.814 40.094 11.070 1.00 56.07 ? 43 LYS J CG 1 ATOM 5355 C CD . LYS D 2 43 ? -33.108 39.730 12.553 1.00 66.25 ? 43 LYS J CD 1 ATOM 5356 C CE . LYS D 2 43 ? -31.958 39.948 13.570 1.00 69.45 ? 43 LYS J CE 1 ATOM 5357 N NZ . LYS D 2 43 ? -31.469 41.320 13.607 1.00 74.41 ? 43 LYS J NZ 1 ATOM 5358 N N . ARG D 2 44 ? -32.901 35.823 8.464 1.00 19.56 ? 44 ARG J N 1 ATOM 5359 C CA . ARG D 2 44 ? -33.588 34.818 7.664 1.00 17.18 ? 44 ARG J CA 1 ATOM 5360 C C . ARG D 2 44 ? -34.059 33.789 8.663 1.00 14.12 ? 44 ARG J C 1 ATOM 5361 O O . ARG D 2 44 ? -33.297 33.523 9.615 1.00 6.15 ? 44 ARG J O 1 ATOM 5362 C CB . ARG D 2 44 ? -32.620 34.183 6.630 1.00 26.38 ? 44 ARG J CB 1 ATOM 5363 C CG . ARG D 2 44 ? -32.665 32.688 6.133 1.00 42.61 ? 44 ARG J CG 1 ATOM 5364 C CD . ARG D 2 44 ? -33.898 32.213 5.281 1.00 54.55 ? 44 ARG J CD 1 ATOM 5365 N NE . ARG D 2 44 ? -33.895 30.814 4.771 1.00 58.13 ? 44 ARG J NE 1 ATOM 5366 C CZ . ARG D 2 44 ? -34.978 30.189 4.216 1.00 56.97 ? 44 ARG J CZ 1 ATOM 5367 N NH1 . ARG D 2 44 ? -36.183 30.765 4.127 1.00 55.07 ? 44 ARG J NH1 1 ATOM 5368 N NH2 . ARG D 2 44 ? -34.876 28.935 3.749 1.00 54.32 ? 44 ARG J NH2 1 ATOM 5369 N N . LEU D 2 45 ? -35.296 33.268 8.475 1.00 10.86 ? 45 LEU J N 1 ATOM 5370 C CA . LEU D 2 45 ? -35.804 32.199 9.342 1.00 15.29 ? 45 LEU J CA 1 ATOM 5371 C C . LEU D 2 45 ? -35.707 30.732 8.832 1.00 14.98 ? 45 LEU J C 1 ATOM 5372 O O . LEU D 2 45 ? -35.963 30.444 7.662 1.00 17.12 ? 45 LEU J O 1 ATOM 5373 C CB . LEU D 2 45 ? -37.240 32.555 9.705 1.00 8.34 ? 45 LEU J CB 1 ATOM 5374 C CG . LEU D 2 45 ? -37.470 33.806 10.563 1.00 12.37 ? 45 LEU J CG 1 ATOM 5375 C CD1 . LEU D 2 45 ? -38.953 33.988 10.851 1.00 14.23 ? 45 LEU J CD1 1 ATOM 5376 C CD2 . LEU D 2 45 ? -36.794 33.648 11.920 1.00 13.00 ? 45 LEU J CD2 1 ATOM 5377 N N . GLU D 2 46 ? -35.331 29.715 9.615 1.00 14.73 ? 46 GLU J N 1 ATOM 5378 C CA . GLU D 2 46 ? -35.173 28.360 9.088 1.00 20.15 ? 46 GLU J CA 1 ATOM 5379 C C . GLU D 2 46 ? -35.681 27.342 10.075 1.00 22.79 ? 46 GLU J C 1 ATOM 5380 O O . GLU D 2 46 ? -35.295 27.383 11.244 1.00 28.74 ? 46 GLU J O 1 ATOM 5381 C CB . GLU D 2 46 ? -33.738 27.971 8.845 1.00 29.74 ? 46 GLU J CB 1 ATOM 5382 C CG . GLU D 2 46 ? -32.834 28.882 8.002 1.00 40.92 ? 46 GLU J CG 1 ATOM 5383 C CD . GLU D 2 46 ? -31.386 28.389 7.866 1.00 45.37 ? 46 GLU J CD 1 ATOM 5384 O OE1 . GLU D 2 46 ? -31.124 27.221 8.185 1.00 47.36 ? 46 GLU J OE1 1 ATOM 5385 O OE2 . GLU D 2 46 ? -30.531 29.175 7.429 1.00 45.95 ? 46 GLU J OE2 1 ATOM 5386 N N . TRP D 2 47 ? -36.559 26.434 9.660 1.00 25.81 ? 47 TRP J N 1 ATOM 5387 C CA . TRP D 2 47 ? -37.139 25.415 10.542 1.00 25.00 ? 47 TRP J CA 1 ATOM 5388 C C . TRP D 2 47 ? -36.027 24.413 10.840 1.00 21.61 ? 47 TRP J C 1 ATOM 5389 O O . TRP D 2 47 ? -35.359 24.066 9.866 1.00 29.35 ? 47 TRP J O 1 ATOM 5390 C CB . TRP D 2 47 ? -38.367 24.799 9.771 1.00 28.03 ? 47 TRP J CB 1 ATOM 5391 C CG . TRP D 2 47 ? -38.899 23.507 10.387 1.00 30.75 ? 47 TRP J CG 1 ATOM 5392 C CD1 . TRP D 2 47 ? -39.548 23.530 11.589 1.00 26.77 ? 47 TRP J CD1 1 ATOM 5393 C CD2 . TRP D 2 47 ? -38.667 22.224 9.911 1.00 29.07 ? 47 TRP J CD2 1 ATOM 5394 N NE1 . TRP D 2 47 ? -39.689 22.268 11.898 1.00 31.90 ? 47 TRP J NE1 1 ATOM 5395 C CE2 . TRP D 2 47 ? -39.185 21.454 10.937 1.00 30.56 ? 47 TRP J CE2 1 ATOM 5396 C CE3 . TRP D 2 47 ? -38.096 21.626 8.801 1.00 20.31 ? 47 TRP J CE3 1 ATOM 5397 C CZ2 . TRP D 2 47 ? -39.126 20.073 10.859 1.00 27.02 ? 47 TRP J CZ2 1 ATOM 5398 C CZ3 . TRP D 2 47 ? -38.046 20.262 8.725 1.00 19.57 ? 47 TRP J CZ3 1 ATOM 5399 C CH2 . TRP D 2 47 ? -38.555 19.492 9.748 1.00 26.63 ? 47 TRP J CH2 1 ATOM 5400 N N . VAL D 2 48 ? -35.677 23.932 12.034 1.00 17.44 ? 48 VAL J N 1 ATOM 5401 C CA . VAL D 2 48 ? -34.607 22.917 12.108 1.00 19.90 ? 48 VAL J CA 1 ATOM 5402 C C . VAL D 2 48 ? -34.866 21.566 12.821 1.00 21.14 ? 48 VAL J C 1 ATOM 5403 O O . VAL D 2 48 ? -33.942 20.799 13.118 1.00 23.76 ? 48 VAL J O 1 ATOM 5404 C CB . VAL D 2 48 ? -33.312 23.522 12.726 1.00 15.25 ? 48 VAL J CB 1 ATOM 5405 C CG1 . VAL D 2 48 ? -32.848 24.633 11.813 1.00 13.05 ? 48 VAL J CG1 1 ATOM 5406 C CG2 . VAL D 2 48 ? -33.527 23.944 14.160 1.00 15.60 ? 48 VAL J CG2 1 ATOM 5407 N N . ALA D 2 49 ? -36.106 21.188 13.092 1.00 14.78 ? 49 ALA J N 1 ATOM 5408 C CA . ALA D 2 49 ? -36.412 19.921 13.720 1.00 14.64 ? 49 ALA J CA 1 ATOM 5409 C C . ALA D 2 49 ? -37.894 19.947 13.965 1.00 16.80 ? 49 ALA J C 1 ATOM 5410 O O . ALA D 2 49 ? -38.487 21.025 14.006 1.00 21.35 ? 49 ALA J O 1 ATOM 5411 C CB . ALA D 2 49 ? -35.748 19.726 15.090 1.00 2.60 ? 49 ALA J CB 1 ATOM 5412 N N . GLY D 2 50 ? -38.525 18.803 14.116 1.00 20.84 ? 50 GLY J N 1 ATOM 5413 C CA . GLY D 2 50 ? -39.940 18.734 14.419 1.00 23.59 ? 50 GLY J CA 1 ATOM 5414 C C . GLY D 2 50 ? -40.157 17.436 15.177 1.00 25.74 ? 50 GLY J C 1 ATOM 5415 O O . GLY D 2 50 ? -39.493 16.429 14.885 1.00 28.66 ? 50 GLY J O 1 ATOM 5416 N N . ILE D 2 51 ? -41.022 17.414 16.178 1.00 22.77 ? 51 ILE J N 1 ATOM 5417 C CA . ILE D 2 51 ? -41.276 16.188 16.883 1.00 17.98 ? 51 ILE J CA 1 ATOM 5418 C C . ILE D 2 51 ? -42.758 16.193 17.202 1.00 26.80 ? 51 ILE J C 1 ATOM 5419 O O . ILE D 2 51 ? -43.367 17.182 17.636 1.00 31.01 ? 51 ILE J O 1 ATOM 5420 C CB . ILE D 2 51 ? -40.423 16.154 18.121 1.00 12.01 ? 51 ILE J CB 1 ATOM 5421 C CG1 . ILE D 2 51 ? -40.652 14.838 18.855 1.00 13.75 ? 51 ILE J CG1 1 ATOM 5422 C CG2 . ILE D 2 51 ? -40.761 17.367 18.998 1.00 23.33 ? 51 ILE J CG2 1 ATOM 5423 C CD1 . ILE D 2 51 ? -39.822 14.606 20.130 1.00 3.01 ? 51 ILE J CD1 1 ATOM 5424 N N . SER D 2 52 ? -43.374 15.071 16.889 1.00 33.89 ? 52 SER J N 1 ATOM 5425 C CA . SER D 2 52 ? -44.784 14.889 17.158 1.00 39.38 ? 52 SER J CA 1 ATOM 5426 C C . SER D 2 52 ? -45.020 14.552 18.645 1.00 40.03 ? 52 SER J C 1 ATOM 5427 O O . SER D 2 52 ? -44.291 13.776 19.261 1.00 44.48 ? 52 SER J O 1 ATOM 5428 C CB . SER D 2 52 ? -45.244 13.800 16.210 1.00 36.07 ? 52 SER J CB 1 ATOM 5429 O OG . SER D 2 52 ? -44.277 12.755 16.206 1.00 41.33 ? 52 SER J OG 1 ATOM 5430 N N . SER D 2 53 A -45.979 15.219 19.266 1.00 37.70 ? 52 SER J N 1 ATOM 5431 C CA . SER D 2 53 A -46.447 15.028 20.631 1.00 36.08 ? 52 SER J CA 1 ATOM 5432 C C . SER D 2 53 A -46.075 13.874 21.517 1.00 33.99 ? 52 SER J C 1 ATOM 5433 O O . SER D 2 53 A -45.942 14.065 22.719 1.00 35.67 ? 52 SER J O 1 ATOM 5434 C CB . SER D 2 53 A -47.946 15.077 20.623 1.00 39.38 ? 52 SER J CB 1 ATOM 5435 O OG . SER D 2 53 A -48.380 14.228 19.563 1.00 45.43 ? 52 SER J OG 1 ATOM 5436 N N . GLY D 2 54 ? -45.980 12.662 21.018 1.00 34.12 ? 53 GLY J N 1 ATOM 5437 C CA . GLY D 2 54 ? -45.591 11.560 21.876 1.00 42.61 ? 53 GLY J CA 1 ATOM 5438 C C . GLY D 2 54 ? -44.100 11.286 21.800 1.00 47.65 ? 53 GLY J C 1 ATOM 5439 O O . GLY D 2 54 ? -43.618 10.293 22.357 1.00 52.32 ? 53 GLY J O 1 ATOM 5440 N N . GLY D 2 55 ? -43.359 12.172 21.118 1.00 48.16 ? 54 GLY J N 1 ATOM 5441 C CA . GLY D 2 55 ? -41.958 11.958 20.789 1.00 42.97 ? 54 GLY J CA 1 ATOM 5442 C C . GLY D 2 55 ? -41.848 10.803 19.810 1.00 39.81 ? 54 GLY J C 1 ATOM 5443 O O . GLY D 2 55 ? -40.790 10.211 19.628 1.00 38.94 ? 54 GLY J O 1 ATOM 5444 N N . SER D 2 56 ? -42.945 10.522 19.120 1.00 38.52 ? 55 SER J N 1 ATOM 5445 C CA . SER D 2 56 ? -43.030 9.322 18.329 1.00 43.51 ? 55 SER J CA 1 ATOM 5446 C C . SER D 2 56 ? -42.050 9.387 17.166 1.00 41.25 ? 55 SER J C 1 ATOM 5447 O O . SER D 2 56 ? -41.303 8.439 16.947 1.00 41.42 ? 55 SER J O 1 ATOM 5448 C CB . SER D 2 56 ? -44.492 9.168 17.841 1.00 50.10 ? 55 SER J CB 1 ATOM 5449 O OG . SER D 2 56 ? -45.507 9.394 18.825 1.00 52.70 ? 55 SER J OG 1 ATOM 5450 N N . TYR D 2 57 ? -42.002 10.486 16.415 1.00 38.68 ? 56 TYR J N 1 ATOM 5451 C CA . TYR D 2 57 ? -41.149 10.560 15.240 1.00 38.71 ? 56 TYR J CA 1 ATOM 5452 C C . TYR D 2 57 ? -40.772 12.006 15.027 1.00 31.01 ? 56 TYR J C 1 ATOM 5453 O O . TYR D 2 57 ? -41.605 12.921 15.118 1.00 27.38 ? 56 TYR J O 1 ATOM 5454 C CB . TYR D 2 57 ? -41.828 10.067 13.917 1.00 47.08 ? 56 TYR J CB 1 ATOM 5455 C CG . TYR D 2 57 ? -43.275 9.558 13.959 1.00 52.36 ? 56 TYR J CG 1 ATOM 5456 C CD1 . TYR D 2 57 ? -44.299 10.417 14.286 1.00 55.92 ? 56 TYR J CD1 1 ATOM 5457 C CD2 . TYR D 2 57 ? -43.571 8.228 13.691 1.00 55.18 ? 56 TYR J CD2 1 ATOM 5458 C CE1 . TYR D 2 57 ? -45.593 9.957 14.359 1.00 55.31 ? 56 TYR J CE1 1 ATOM 5459 C CE2 . TYR D 2 57 ? -44.871 7.755 13.754 1.00 54.31 ? 56 TYR J CE2 1 ATOM 5460 C CZ . TYR D 2 57 ? -45.861 8.641 14.093 1.00 55.19 ? 56 TYR J CZ 1 ATOM 5461 O OH . TYR D 2 57 ? -47.162 8.230 14.185 1.00 59.53 ? 56 TYR J OH 1 ATOM 5462 N N . THR D 2 58 ? -39.488 12.124 14.749 1.00 22.92 ? 57 THR J N 1 ATOM 5463 C CA . THR D 2 58 ? -38.796 13.377 14.580 1.00 19.66 ? 57 THR J CA 1 ATOM 5464 C C . THR D 2 58 ? -38.683 13.747 13.121 1.00 20.09 ? 57 THR J C 1 ATOM 5465 O O . THR D 2 58 ? -38.510 12.859 12.300 1.00 20.37 ? 57 THR J O 1 ATOM 5466 C CB . THR D 2 58 ? -37.440 13.209 15.189 1.00 17.87 ? 57 THR J CB 1 ATOM 5467 O OG1 . THR D 2 58 ? -36.888 12.097 14.511 1.00 10.90 ? 57 THR J OG1 1 ATOM 5468 C CG2 . THR D 2 58 ? -37.447 12.884 16.676 1.00 25.74 ? 57 THR J CG2 1 ATOM 5469 N N . PHE D 2 59 ? -38.737 14.990 12.715 1.00 19.59 ? 58 PHE J N 1 ATOM 5470 C CA . PHE D 2 59 ? -38.643 15.371 11.332 1.00 24.39 ? 58 PHE J CA 1 ATOM 5471 C C . PHE D 2 59 ? -37.468 16.355 11.276 1.00 24.49 ? 58 PHE J C 1 ATOM 5472 O O . PHE D 2 59 ? -37.237 17.039 12.260 1.00 32.61 ? 58 PHE J O 1 ATOM 5473 C CB . PHE D 2 59 ? -39.988 15.981 10.959 1.00 30.87 ? 58 PHE J CB 1 ATOM 5474 C CG . PHE D 2 59 ? -41.164 14.986 10.968 1.00 39.05 ? 58 PHE J CG 1 ATOM 5475 C CD1 . PHE D 2 59 ? -41.468 14.176 12.055 1.00 40.25 ? 58 PHE J CD1 1 ATOM 5476 C CD2 . PHE D 2 59 ? -41.959 14.876 9.847 1.00 40.81 ? 58 PHE J CD2 1 ATOM 5477 C CE1 . PHE D 2 59 ? -42.521 13.285 12.039 1.00 43.45 ? 58 PHE J CE1 1 ATOM 5478 C CE2 . PHE D 2 59 ? -43.017 13.981 9.837 1.00 41.50 ? 58 PHE J CE2 1 ATOM 5479 C CZ . PHE D 2 59 ? -43.306 13.184 10.921 1.00 41.69 ? 58 PHE J CZ 1 ATOM 5480 N N . TYR D 2 60 ? -36.635 16.453 10.241 1.00 25.64 ? 59 TYR J N 1 ATOM 5481 C CA . TYR D 2 60 ? -35.457 17.320 10.115 1.00 22.76 ? 59 TYR J CA 1 ATOM 5482 C C . TYR D 2 60 ? -35.383 17.732 8.665 1.00 31.56 ? 59 TYR J C 1 ATOM 5483 O O . TYR D 2 60 ? -35.851 16.993 7.779 1.00 35.40 ? 59 TYR J O 1 ATOM 5484 C CB . TYR D 2 60 ? -34.157 16.643 10.341 1.00 15.01 ? 59 TYR J CB 1 ATOM 5485 C CG . TYR D 2 60 ? -34.080 16.217 11.764 1.00 15.46 ? 59 TYR J CG 1 ATOM 5486 C CD1 . TYR D 2 60 ? -34.564 15.001 12.125 1.00 15.32 ? 59 TYR J CD1 1 ATOM 5487 C CD2 . TYR D 2 60 ? -33.559 17.070 12.692 1.00 21.26 ? 59 TYR J CD2 1 ATOM 5488 C CE1 . TYR D 2 60 ? -34.535 14.607 13.441 1.00 23.05 ? 59 TYR J CE1 1 ATOM 5489 C CE2 . TYR D 2 60 ? -33.524 16.688 14.005 1.00 24.43 ? 59 TYR J CE2 1 ATOM 5490 C CZ . TYR D 2 60 ? -34.015 15.455 14.366 1.00 24.09 ? 59 TYR J CZ 1 ATOM 5491 O OH . TYR D 2 60 ? -33.961 15.068 15.678 1.00 22.49 ? 59 TYR J OH 1 ATOM 5492 N N . PRO D 2 61 ? -34.852 18.916 8.363 1.00 33.59 ? 60 PRO J N 1 ATOM 5493 C CA . PRO D 2 61 ? -34.465 19.263 7.015 1.00 34.62 ? 60 PRO J CA 1 ATOM 5494 C C . PRO D 2 61 ? -33.073 18.673 6.752 1.00 39.31 ? 60 PRO J C 1 ATOM 5495 O O . PRO D 2 61 ? -32.448 18.112 7.666 1.00 40.52 ? 60 PRO J O 1 ATOM 5496 C CB . PRO D 2 61 ? -34.590 20.760 7.049 1.00 29.59 ? 60 PRO J CB 1 ATOM 5497 C CG . PRO D 2 61 ? -34.081 21.120 8.403 1.00 30.41 ? 60 PRO J CG 1 ATOM 5498 C CD . PRO D 2 61 ? -34.612 20.007 9.299 1.00 34.43 ? 60 PRO J CD 1 ATOM 5499 N N . ASP D 2 62 ? -32.505 18.819 5.553 1.00 40.98 ? 61 ASP J N 1 ATOM 5500 C CA . ASP D 2 62 ? -31.256 18.141 5.247 1.00 44.56 ? 61 ASP J CA 1 ATOM 5501 C C . ASP D 2 62 ? -29.989 18.727 5.871 1.00 43.84 ? 61 ASP J C 1 ATOM 5502 O O . ASP D 2 62 ? -29.192 17.993 6.443 1.00 39.51 ? 61 ASP J O 1 ATOM 5503 C CB . ASP D 2 62 ? -31.186 18.065 3.722 1.00 50.10 ? 61 ASP J CB 1 ATOM 5504 C CG . ASP D 2 62 ? -32.268 17.196 3.036 1.00 53.90 ? 61 ASP J CG 1 ATOM 5505 O OD1 . ASP D 2 62 ? -33.304 16.861 3.627 1.00 55.04 ? 61 ASP J OD1 1 ATOM 5506 O OD2 . ASP D 2 62 ? -32.070 16.852 1.872 1.00 51.33 ? 61 ASP J OD2 1 ATOM 5507 N N . THR D 2 63 ? -29.812 20.041 5.891 1.00 46.68 ? 62 THR J N 1 ATOM 5508 C CA . THR D 2 63 ? -28.662 20.704 6.518 1.00 46.68 ? 62 THR J CA 1 ATOM 5509 C C . THR D 2 63 ? -28.316 20.268 7.944 1.00 40.48 ? 62 THR J C 1 ATOM 5510 O O . THR D 2 63 ? -27.164 20.282 8.375 1.00 46.43 ? 62 THR J O 1 ATOM 5511 C CB . THR D 2 63 ? -28.889 22.267 6.514 1.00 51.69 ? 62 THR J CB 1 ATOM 5512 O OG1 . THR D 2 63 ? -30.142 22.615 7.133 1.00 50.31 ? 62 THR J OG1 1 ATOM 5513 C CG2 . THR D 2 63 ? -28.919 22.773 5.081 1.00 54.97 ? 62 THR J CG2 1 ATOM 5514 N N . VAL D 2 64 ? -29.310 19.961 8.755 1.00 27.97 ? 63 VAL J N 1 ATOM 5515 C CA . VAL D 2 64 ? -28.974 19.581 10.103 1.00 22.54 ? 63 VAL J CA 1 ATOM 5516 C C . VAL D 2 64 ? -29.034 18.095 10.165 1.00 21.81 ? 63 VAL J C 1 ATOM 5517 O O . VAL D 2 64 ? -28.512 17.516 11.121 1.00 22.32 ? 63 VAL J O 1 ATOM 5518 C CB . VAL D 2 64 ? -29.949 20.186 11.122 1.00 17.99 ? 63 VAL J CB 1 ATOM 5519 C CG1 . VAL D 2 64 ? -29.995 21.673 10.828 1.00 21.53 ? 63 VAL J CG1 1 ATOM 5520 C CG2 . VAL D 2 64 ? -31.352 19.626 11.021 1.00 17.85 ? 63 VAL J CG2 1 ATOM 5521 N N . LYS D 2 65 ? -29.636 17.475 9.147 1.00 26.46 ? 64 LYS J N 1 ATOM 5522 C CA . LYS D 2 65 ? -29.895 16.060 9.199 1.00 34.00 ? 64 LYS J CA 1 ATOM 5523 C C . LYS D 2 65 ? -28.586 15.364 9.345 1.00 32.00 ? 64 LYS J C 1 ATOM 5524 O O . LYS D 2 65 ? -27.611 15.612 8.660 1.00 36.65 ? 64 LYS J O 1 ATOM 5525 C CB . LYS D 2 65 ? -30.580 15.571 7.948 1.00 41.86 ? 64 LYS J CB 1 ATOM 5526 C CG . LYS D 2 65 ? -31.002 14.096 8.006 1.00 50.16 ? 64 LYS J CG 1 ATOM 5527 C CD . LYS D 2 65 ? -32.380 13.821 7.382 1.00 56.44 ? 64 LYS J CD 1 ATOM 5528 C CE . LYS D 2 65 ? -32.710 14.646 6.119 1.00 60.06 ? 64 LYS J CE 1 ATOM 5529 N NZ . LYS D 2 65 ? -31.681 14.598 5.090 1.00 60.31 ? 64 LYS J NZ 1 ATOM 5530 N N . GLY D 2 66 ? -28.572 14.612 10.415 1.00 31.12 ? 65 GLY J N 1 ATOM 5531 C CA . GLY D 2 66 ? -27.392 13.866 10.726 1.00 32.59 ? 65 GLY J CA 1 ATOM 5532 C C . GLY D 2 66 ? -26.892 14.329 12.056 1.00 35.00 ? 65 GLY J C 1 ATOM 5533 O O . GLY D 2 66 ? -26.775 13.538 13.003 1.00 37.49 ? 65 GLY J O 1 ATOM 5534 N N . ARG D 2 67 ? -26.770 15.659 12.089 1.00 31.91 ? 66 ARG J N 1 ATOM 5535 C CA . ARG D 2 67 ? -26.125 16.370 13.189 1.00 27.06 ? 66 ARG J CA 1 ATOM 5536 C C . ARG D 2 67 ? -26.972 16.676 14.438 1.00 27.43 ? 66 ARG J C 1 ATOM 5537 O O . ARG D 2 67 ? -26.425 16.701 15.562 1.00 33.84 ? 66 ARG J O 1 ATOM 5538 C CB . ARG D 2 67 ? -25.555 17.656 12.615 1.00 21.05 ? 66 ARG J CB 1 ATOM 5539 C CG . ARG D 2 67 ? -25.104 17.616 11.143 1.00 21.83 ? 66 ARG J CG 1 ATOM 5540 C CD . ARG D 2 67 ? -24.926 18.956 10.456 1.00 16.22 ? 66 ARG J CD 1 ATOM 5541 N NE . ARG D 2 67 ? -24.282 19.777 11.455 1.00 20.21 ? 66 ARG J NE 1 ATOM 5542 C CZ . ARG D 2 67 ? -24.641 21.034 11.656 1.00 19.20 ? 66 ARG J CZ 1 ATOM 5543 N NH1 . ARG D 2 67 ? -25.374 21.733 10.778 1.00 10.96 ? 66 ARG J NH1 1 ATOM 5544 N NH2 . ARG D 2 67 ? -24.164 21.583 12.757 1.00 23.87 ? 66 ARG J NH2 1 ATOM 5545 N N . PHE D 2 68 ? -28.274 16.962 14.353 1.00 20.57 ? 67 PHE J N 1 ATOM 5546 C CA . PHE D 2 68 ? -28.981 17.257 15.586 1.00 23.84 ? 67 PHE J CA 1 ATOM 5547 C C . PHE D 2 68 ? -30.158 16.329 15.810 1.00 27.54 ? 67 PHE J C 1 ATOM 5548 O O . PHE D 2 68 ? -30.846 15.950 14.845 1.00 25.35 ? 67 PHE J O 1 ATOM 5549 C CB . PHE D 2 68 ? -29.616 18.624 15.660 1.00 24.60 ? 67 PHE J CB 1 ATOM 5550 C CG . PHE D 2 68 ? -28.880 19.850 15.213 1.00 24.14 ? 67 PHE J CG 1 ATOM 5551 C CD1 . PHE D 2 68 ? -27.516 19.934 15.273 1.00 25.22 ? 67 PHE J CD1 1 ATOM 5552 C CD2 . PHE D 2 68 ? -29.641 20.868 14.700 1.00 22.06 ? 67 PHE J CD2 1 ATOM 5553 C CE1 . PHE D 2 68 ? -26.895 21.058 14.801 1.00 21.59 ? 67 PHE J CE1 1 ATOM 5554 C CE2 . PHE D 2 68 ? -29.014 21.979 14.238 1.00 21.24 ? 67 PHE J CE2 1 ATOM 5555 C CZ . PHE D 2 68 ? -27.646 22.071 14.286 1.00 21.63 ? 67 PHE J CZ 1 ATOM 5556 N N . ILE D 2 69 ? -30.420 16.036 17.090 1.00 24.81 ? 68 ILE J N 1 ATOM 5557 C CA . ILE D 2 69 ? -31.568 15.234 17.457 1.00 29.77 ? 68 ILE J CA 1 ATOM 5558 C C . ILE D 2 69 ? -32.501 15.992 18.394 1.00 24.53 ? 68 ILE J C 1 ATOM 5559 O O . ILE D 2 69 ? -32.058 16.614 19.376 1.00 20.04 ? 68 ILE J O 1 ATOM 5560 C CB . ILE D 2 69 ? -31.077 13.868 18.085 1.00 35.28 ? 68 ILE J CB 1 ATOM 5561 C CG1 . ILE D 2 69 ? -31.780 12.767 17.267 1.00 40.46 ? 68 ILE J CG1 1 ATOM 5562 C CG2 . ILE D 2 69 ? -31.419 13.680 19.583 1.00 36.46 ? 68 ILE J CG2 1 ATOM 5563 C CD1 . ILE D 2 69 ? -31.141 11.339 17.276 1.00 42.95 ? 68 ILE J CD1 1 ATOM 5564 N N . ILE D 2 70 ? -33.806 15.858 18.128 1.00 16.45 ? 69 ILE J N 1 ATOM 5565 C CA . ILE D 2 70 ? -34.766 16.582 18.922 1.00 17.47 ? 69 ILE J CA 1 ATOM 5566 C C . ILE D 2 70 ? -35.564 15.754 19.942 1.00 21.33 ? 69 ILE J C 1 ATOM 5567 O O . ILE D 2 70 ? -36.502 15.043 19.613 1.00 28.69 ? 69 ILE J O 1 ATOM 5568 C CB . ILE D 2 70 ? -35.657 17.322 17.936 1.00 6.05 ? 69 ILE J CB 1 ATOM 5569 C CG1 . ILE D 2 70 ? -36.627 18.168 18.738 1.00 2.00 ? 69 ILE J CG1 1 ATOM 5570 C CG2 . ILE D 2 70 ? -36.299 16.360 16.973 1.00 7.45 ? 69 ILE J CG2 1 ATOM 5571 C CD1 . ILE D 2 70 ? -37.683 18.877 17.892 1.00 4.32 ? 69 ILE J CD1 1 ATOM 5572 N N . SER D 2 71 ? -35.197 15.796 21.217 1.00 21.97 ? 70 SER J N 1 ATOM 5573 C CA . SER D 2 71 ? -35.919 15.063 22.253 1.00 23.86 ? 70 SER J CA 1 ATOM 5574 C C . SER D 2 71 ? -37.216 15.773 22.636 1.00 26.27 ? 70 SER J C 1 ATOM 5575 O O . SER D 2 71 ? -37.641 16.721 21.971 1.00 28.78 ? 70 SER J O 1 ATOM 5576 C CB . SER D 2 71 ? -35.045 14.950 23.476 1.00 26.99 ? 70 SER J CB 1 ATOM 5577 O OG . SER D 2 71 ? -33.781 14.400 23.135 1.00 37.51 ? 70 SER J OG 1 ATOM 5578 N N . ARG D 2 72 ? -37.847 15.279 23.700 1.00 25.72 ? 71 ARG J N 1 ATOM 5579 C CA . ARG D 2 72 ? -38.988 15.861 24.402 1.00 23.96 ? 71 ARG J CA 1 ATOM 5580 C C . ARG D 2 72 ? -39.187 14.945 25.609 1.00 23.89 ? 71 ARG J C 1 ATOM 5581 O O . ARG D 2 72 ? -38.555 13.889 25.724 1.00 29.49 ? 71 ARG J O 1 ATOM 5582 C CB . ARG D 2 72 ? -40.340 15.896 23.623 1.00 19.82 ? 71 ARG J CB 1 ATOM 5583 C CG . ARG D 2 72 ? -41.315 14.718 23.582 1.00 15.92 ? 71 ARG J CG 1 ATOM 5584 C CD . ARG D 2 72 ? -42.749 15.229 23.365 1.00 14.06 ? 71 ARG J CD 1 ATOM 5585 N NE . ARG D 2 72 ? -43.021 15.994 22.156 1.00 14.32 ? 71 ARG J NE 1 ATOM 5586 C CZ . ARG D 2 72 ? -43.999 16.926 22.162 1.00 18.58 ? 71 ARG J CZ 1 ATOM 5587 N NH1 . ARG D 2 72 ? -44.710 17.229 23.260 1.00 20.11 ? 71 ARG J NH1 1 ATOM 5588 N NH2 . ARG D 2 72 ? -44.294 17.599 21.053 1.00 15.19 ? 71 ARG J NH2 1 ATOM 5589 N N . ASN D 2 73 ? -40.005 15.333 26.558 1.00 20.27 ? 72 ASN J N 1 ATOM 5590 C CA . ASN D 2 73 ? -40.235 14.522 27.713 1.00 23.09 ? 72 ASN J CA 1 ATOM 5591 C C . ASN D 2 73 ? -41.525 15.066 28.270 1.00 28.02 ? 72 ASN J C 1 ATOM 5592 O O . ASN D 2 73 ? -41.567 16.071 28.987 1.00 33.02 ? 72 ASN J O 1 ATOM 5593 C CB . ASN D 2 73 ? -39.093 14.702 28.673 1.00 23.12 ? 72 ASN J CB 1 ATOM 5594 C CG . ASN D 2 73 ? -39.339 14.115 30.049 1.00 26.76 ? 72 ASN J CG 1 ATOM 5595 O OD1 . ASN D 2 73 ? -40.480 13.945 30.489 1.00 31.48 ? 72 ASN J OD1 1 ATOM 5596 N ND2 . ASN D 2 73 ? -38.294 13.869 30.835 1.00 24.63 ? 72 ASN J ND2 1 ATOM 5597 N N . ASN D 2 74 ? -42.559 14.303 28.010 1.00 28.12 ? 73 ASN J N 1 ATOM 5598 C CA . ASN D 2 74 ? -43.915 14.657 28.359 1.00 30.32 ? 73 ASN J CA 1 ATOM 5599 C C . ASN D 2 74 ? -44.201 14.616 29.835 1.00 32.56 ? 73 ASN J C 1 ATOM 5600 O O . ASN D 2 74 ? -45.332 14.867 30.241 1.00 35.25 ? 73 ASN J O 1 ATOM 5601 C CB . ASN D 2 74 ? -44.887 13.734 27.676 1.00 33.84 ? 73 ASN J CB 1 ATOM 5602 C CG . ASN D 2 74 ? -44.625 13.698 26.192 1.00 39.12 ? 73 ASN J CG 1 ATOM 5603 O OD1 . ASN D 2 74 ? -43.487 13.537 25.761 1.00 42.96 ? 73 ASN J OD1 1 ATOM 5604 N ND2 . ASN D 2 74 ? -45.613 13.822 25.343 1.00 39.94 ? 73 ASN J ND2 1 ATOM 5605 N N . ALA D 2 75 ? -43.243 14.279 30.678 1.00 26.22 ? 74 ALA J N 1 ATOM 5606 C CA . ALA D 2 75 ? -43.545 14.336 32.079 1.00 31.29 ? 74 ALA J CA 1 ATOM 5607 C C . ALA D 2 75 ? -42.992 15.603 32.726 1.00 36.31 ? 74 ALA J C 1 ATOM 5608 O O . ALA D 2 75 ? -43.685 16.375 33.411 1.00 40.59 ? 74 ALA J O 1 ATOM 5609 C CB . ALA D 2 75 ? -42.956 13.104 32.716 1.00 35.95 ? 74 ALA J CB 1 ATOM 5610 N N . ARG D 2 76 ? -41.703 15.857 32.481 1.00 32.54 ? 75 ARG J N 1 ATOM 5611 C CA . ARG D 2 76 ? -40.998 16.965 33.108 1.00 33.90 ? 75 ARG J CA 1 ATOM 5612 C C . ARG D 2 76 ? -41.195 18.308 32.381 1.00 33.48 ? 75 ARG J C 1 ATOM 5613 O O . ARG D 2 76 ? -40.855 19.383 32.897 1.00 34.45 ? 75 ARG J O 1 ATOM 5614 C CB . ARG D 2 76 ? -39.524 16.528 33.181 1.00 38.02 ? 75 ARG J CB 1 ATOM 5615 C CG . ARG D 2 76 ? -38.917 16.393 34.568 1.00 46.62 ? 75 ARG J CG 1 ATOM 5616 C CD . ARG D 2 76 ? -39.688 15.412 35.458 1.00 55.87 ? 75 ARG J CD 1 ATOM 5617 N NE . ARG D 2 76 ? -39.564 15.765 36.869 1.00 64.25 ? 75 ARG J NE 1 ATOM 5618 C CZ . ARG D 2 76 ? -38.830 15.076 37.756 1.00 68.54 ? 75 ARG J CZ 1 ATOM 5619 N NH1 . ARG D 2 76 ? -38.140 13.971 37.434 1.00 70.12 ? 75 ARG J NH1 1 ATOM 5620 N NH2 . ARG D 2 76 ? -38.796 15.512 39.017 1.00 70.69 ? 75 ARG J NH2 1 ATOM 5621 N N . ASN D 2 77 ? -41.741 18.182 31.165 1.00 26.19 ? 76 ASN J N 1 ATOM 5622 C CA . ASN D 2 77 ? -42.077 19.237 30.226 1.00 27.74 ? 76 ASN J CA 1 ATOM 5623 C C . ASN D 2 77 ? -40.866 19.935 29.727 1.00 28.99 ? 76 ASN J C 1 ATOM 5624 O O . ASN D 2 77 ? -40.436 20.949 30.267 1.00 39.91 ? 76 ASN J O 1 ATOM 5625 C CB . ASN D 2 77 ? -42.964 20.300 30.800 1.00 28.79 ? 76 ASN J CB 1 ATOM 5626 C CG . ASN D 2 77 ? -44.274 19.674 31.159 1.00 33.60 ? 76 ASN J CG 1 ATOM 5627 O OD1 . ASN D 2 77 ? -45.042 19.207 30.304 1.00 30.95 ? 76 ASN J OD1 1 ATOM 5628 N ND2 . ASN D 2 77 ? -44.479 19.636 32.473 1.00 35.39 ? 76 ASN J ND2 1 ATOM 5629 N N . THR D 2 78 ? -40.281 19.353 28.696 1.00 20.27 ? 77 THR J N 1 ATOM 5630 C CA . THR D 2 78 ? -39.031 19.825 28.170 1.00 16.84 ? 77 THR J CA 1 ATOM 5631 C C . THR D 2 78 ? -38.957 19.382 26.735 1.00 16.96 ? 77 THR J C 1 ATOM 5632 O O . THR D 2 78 ? -39.338 18.253 26.460 1.00 17.46 ? 77 THR J O 1 ATOM 5633 C CB . THR D 2 78 ? -37.892 19.170 28.920 1.00 26.38 ? 77 THR J CB 1 ATOM 5634 O OG1 . THR D 2 78 ? -37.964 19.596 30.283 1.00 29.30 ? 77 THR J OG1 1 ATOM 5635 C CG2 . THR D 2 78 ? -36.540 19.467 28.262 1.00 29.32 ? 77 THR J CG2 1 ATOM 5636 N N . LEU D 2 79 ? -38.533 20.249 25.837 1.00 19.59 ? 78 LEU J N 1 ATOM 5637 C CA . LEU D 2 79 ? -38.187 19.923 24.471 1.00 17.35 ? 78 LEU J CA 1 ATOM 5638 C C . LEU D 2 79 ? -36.689 20.191 24.427 1.00 18.08 ? 78 LEU J C 1 ATOM 5639 O O . LEU D 2 79 ? -36.201 20.852 25.356 1.00 25.03 ? 78 LEU J O 1 ATOM 5640 C CB . LEU D 2 79 ? -38.855 20.852 23.524 1.00 18.05 ? 78 LEU J CB 1 ATOM 5641 C CG . LEU D 2 79 ? -38.613 20.490 22.090 1.00 21.29 ? 78 LEU J CG 1 ATOM 5642 C CD1 . LEU D 2 79 ? -39.478 19.289 21.758 1.00 19.13 ? 78 LEU J CD1 1 ATOM 5643 C CD2 . LEU D 2 79 ? -38.919 21.671 21.192 1.00 24.27 ? 78 LEU J CD2 1 ATOM 5644 N N . SER D 2 80 ? -35.868 19.791 23.453 1.00 16.46 ? 79 SER J N 1 ATOM 5645 C CA . SER D 2 80 ? -34.439 20.116 23.488 1.00 17.68 ? 79 SER J CA 1 ATOM 5646 C C . SER D 2 80 ? -33.833 20.045 22.115 1.00 19.83 ? 79 SER J C 1 ATOM 5647 O O . SER D 2 80 ? -34.529 19.647 21.186 1.00 30.60 ? 79 SER J O 1 ATOM 5648 C CB . SER D 2 80 ? -33.659 19.148 24.335 1.00 17.61 ? 79 SER J CB 1 ATOM 5649 O OG . SER D 2 80 ? -34.343 18.815 25.531 1.00 24.28 ? 79 SER J OG 1 ATOM 5650 N N . LEU D 2 81 ? -32.607 20.474 21.924 1.00 20.02 ? 80 LEU J N 1 ATOM 5651 C CA . LEU D 2 81 ? -31.870 20.170 20.720 1.00 19.59 ? 80 LEU J CA 1 ATOM 5652 C C . LEU D 2 81 ? -30.493 19.763 21.194 1.00 28.76 ? 80 LEU J C 1 ATOM 5653 O O . LEU D 2 81 ? -29.918 20.406 22.085 1.00 27.87 ? 80 LEU J O 1 ATOM 5654 C CB . LEU D 2 81 ? -31.616 21.313 19.807 1.00 16.51 ? 80 LEU J CB 1 ATOM 5655 C CG . LEU D 2 81 ? -32.528 21.563 18.661 1.00 17.13 ? 80 LEU J CG 1 ATOM 5656 C CD1 . LEU D 2 81 ? -31.766 22.304 17.578 1.00 18.15 ? 80 LEU J CD1 1 ATOM 5657 C CD2 . LEU D 2 81 ? -32.989 20.275 18.084 1.00 15.93 ? 80 LEU J CD2 1 ATOM 5658 N N . GLN D 2 82 ? -30.042 18.623 20.665 1.00 34.85 ? 81 GLN J N 1 ATOM 5659 C CA . GLN D 2 82 ? -28.701 18.096 20.880 1.00 32.73 ? 81 GLN J CA 1 ATOM 5660 C C . GLN D 2 82 ? -28.059 18.465 19.548 1.00 35.47 ? 81 GLN J C 1 ATOM 5661 O O . GLN D 2 82 ? -28.548 18.105 18.468 1.00 36.80 ? 81 GLN J O 1 ATOM 5662 C CB . GLN D 2 82 ? -28.711 16.584 21.050 1.00 31.86 ? 81 GLN J CB 1 ATOM 5663 C CG . GLN D 2 82 ? -27.332 15.981 21.208 1.00 37.41 ? 81 GLN J CG 1 ATOM 5664 C CD . GLN D 2 82 ? -26.707 16.361 22.541 1.00 48.46 ? 81 GLN J CD 1 ATOM 5665 O OE1 . GLN D 2 82 ? -27.372 16.320 23.581 1.00 55.48 ? 81 GLN J OE1 1 ATOM 5666 N NE2 . GLN D 2 82 ? -25.432 16.737 22.595 1.00 45.14 ? 81 GLN J NE2 1 ATOM 5667 N N . MET D 2 83 ? -27.012 19.273 19.621 1.00 35.66 ? 82 MET J N 1 ATOM 5668 C CA . MET D 2 83 ? -26.309 19.762 18.454 1.00 31.15 ? 82 MET J CA 1 ATOM 5669 C C . MET D 2 83 ? -24.928 19.177 18.616 1.00 28.20 ? 82 MET J C 1 ATOM 5670 O O . MET D 2 83 ? -24.337 19.284 19.708 1.00 17.64 ? 82 MET J O 1 ATOM 5671 C CB . MET D 2 83 ? -26.242 21.294 18.471 1.00 33.15 ? 82 MET J CB 1 ATOM 5672 C CG . MET D 2 83 ? -27.613 21.923 18.692 1.00 37.70 ? 82 MET J CG 1 ATOM 5673 S SD . MET D 2 83 ? -27.642 23.720 18.807 1.00 36.85 ? 82 MET J SD 1 ATOM 5674 C CE . MET D 2 83 ? -27.893 23.877 17.079 1.00 29.19 ? 82 MET J CE 1 ATOM 5675 N N . SER D 2 84 A -24.432 18.521 17.570 1.00 27.68 ? 82 SER J N 1 ATOM 5676 C CA . SER D 2 84 A -23.081 17.990 17.610 1.00 25.82 ? 82 SER J CA 1 ATOM 5677 C C . SER D 2 84 A -22.491 18.378 16.267 1.00 26.19 ? 82 SER J C 1 ATOM 5678 O O . SER D 2 84 A -23.262 18.594 15.313 1.00 25.54 ? 82 SER J O 1 ATOM 5679 C CB . SER D 2 84 A -23.139 16.485 17.780 1.00 26.57 ? 82 SER J CB 1 ATOM 5680 O OG . SER D 2 84 A -24.424 15.938 18.126 1.00 33.82 ? 82 SER J OG 1 ATOM 5681 N N . SER D 2 85 B -21.160 18.489 16.171 1.00 27.09 ? 82 SER J N 1 ATOM 5682 C CA . SER D 2 85 B -20.474 18.864 14.926 1.00 30.39 ? 82 SER J CA 1 ATOM 5683 C C . SER D 2 85 B -21.011 20.162 14.383 1.00 27.98 ? 82 SER J C 1 ATOM 5684 O O . SER D 2 85 B -21.515 20.304 13.267 1.00 29.29 ? 82 SER J O 1 ATOM 5685 C CB . SER D 2 85 B -20.611 17.798 13.814 1.00 33.46 ? 82 SER J CB 1 ATOM 5686 O OG . SER D 2 85 B -19.547 16.839 13.862 1.00 44.85 ? 82 SER J OG 1 ATOM 5687 N N . LEU D 2 86 C -20.912 21.104 15.310 1.00 23.82 ? 82 LEU J N 1 ATOM 5688 C CA . LEU D 2 86 C -21.406 22.424 15.034 1.00 21.10 ? 82 LEU J CA 1 ATOM 5689 C C . LEU D 2 86 C -20.536 23.116 13.989 1.00 22.90 ? 82 LEU J C 1 ATOM 5690 O O . LEU D 2 86 C -19.305 23.068 14.008 1.00 21.69 ? 82 LEU J O 1 ATOM 5691 C CB . LEU D 2 86 C -21.452 23.142 16.383 1.00 17.15 ? 82 LEU J CB 1 ATOM 5692 C CG . LEU D 2 86 C -22.667 22.805 17.239 1.00 12.22 ? 82 LEU J CG 1 ATOM 5693 C CD1 . LEU D 2 86 C -22.422 23.198 18.678 1.00 13.39 ? 82 LEU J CD1 1 ATOM 5694 C CD2 . LEU D 2 86 C -23.887 23.515 16.653 1.00 4.97 ? 82 LEU J CD2 1 ATOM 5695 N N . ARG D 2 87 ? -21.229 23.667 13.011 1.00 25.33 ? 83 ARG J N 1 ATOM 5696 C CA . ARG D 2 87 ? -20.678 24.467 11.920 1.00 32.78 ? 83 ARG J CA 1 ATOM 5697 C C . ARG D 2 87 ? -20.838 25.943 12.268 1.00 33.71 ? 83 ARG J C 1 ATOM 5698 O O . ARG D 2 87 ? -21.791 26.302 12.965 1.00 37.62 ? 83 ARG J O 1 ATOM 5699 C CB . ARG D 2 87 ? -21.453 24.213 10.639 1.00 37.46 ? 83 ARG J CB 1 ATOM 5700 C CG . ARG D 2 87 ? -20.682 24.053 9.343 1.00 45.27 ? 83 ARG J CG 1 ATOM 5701 C CD . ARG D 2 87 ? -20.763 22.617 8.780 1.00 51.22 ? 83 ARG J CD 1 ATOM 5702 N NE . ARG D 2 87 ? -22.114 22.154 8.451 1.00 61.86 ? 83 ARG J NE 1 ATOM 5703 C CZ . ARG D 2 87 ? -22.788 22.538 7.350 1.00 67.75 ? 83 ARG J CZ 1 ATOM 5704 N NH1 . ARG D 2 87 ? -22.286 23.408 6.467 1.00 72.17 ? 83 ARG J NH1 1 ATOM 5705 N NH2 . ARG D 2 87 ? -24.016 22.072 7.129 1.00 68.04 ? 83 ARG J NH2 1 ATOM 5706 N N . SER D 2 88 ? -20.001 26.863 11.793 1.00 30.55 ? 84 SER J N 1 ATOM 5707 C CA . SER D 2 88 ? -20.284 28.273 12.024 1.00 30.53 ? 84 SER J CA 1 ATOM 5708 C C . SER D 2 88 ? -21.633 28.647 11.398 1.00 31.85 ? 84 SER J C 1 ATOM 5709 O O . SER D 2 88 ? -22.332 29.522 11.893 1.00 37.80 ? 84 SER J O 1 ATOM 5710 C CB . SER D 2 88 ? -19.201 29.139 11.421 1.00 26.54 ? 84 SER J CB 1 ATOM 5711 O OG . SER D 2 88 ? -19.092 28.882 10.033 1.00 33.32 ? 84 SER J OG 1 ATOM 5712 N N . GLU D 2 89 ? -22.130 27.946 10.371 1.00 36.70 ? 85 GLU J N 1 ATOM 5713 C CA . GLU D 2 89 ? -23.438 28.249 9.806 1.00 39.69 ? 85 GLU J CA 1 ATOM 5714 C C . GLU D 2 89 ? -24.597 27.839 10.739 1.00 39.71 ? 85 GLU J C 1 ATOM 5715 O O . GLU D 2 89 ? -25.754 27.736 10.320 1.00 43.58 ? 85 GLU J O 1 ATOM 5716 C CB . GLU D 2 89 ? -23.541 27.571 8.393 1.00 45.04 ? 85 GLU J CB 1 ATOM 5717 C CG . GLU D 2 89 ? -23.602 26.041 8.154 1.00 55.96 ? 85 GLU J CG 1 ATOM 5718 C CD . GLU D 2 89 ? -24.980 25.372 7.926 1.00 63.64 ? 85 GLU J CD 1 ATOM 5719 O OE1 . GLU D 2 89 ? -25.493 25.452 6.813 1.00 69.24 ? 85 GLU J OE1 1 ATOM 5720 O OE2 . GLU D 2 89 ? -25.544 24.736 8.825 1.00 64.70 ? 85 GLU J OE2 1 ATOM 5721 N N . ASP D 2 90 ? -24.336 27.558 12.022 1.00 34.58 ? 86 ASP J N 1 ATOM 5722 C CA . ASP D 2 90 ? -25.404 27.329 12.984 1.00 30.47 ? 86 ASP J CA 1 ATOM 5723 C C . ASP D 2 90 ? -25.501 28.475 13.990 1.00 24.58 ? 86 ASP J C 1 ATOM 5724 O O . ASP D 2 90 ? -26.228 28.411 14.988 1.00 24.94 ? 86 ASP J O 1 ATOM 5725 C CB . ASP D 2 90 ? -25.161 26.010 13.716 1.00 33.01 ? 86 ASP J CB 1 ATOM 5726 C CG . ASP D 2 90 ? -25.058 24.837 12.755 1.00 31.74 ? 86 ASP J CG 1 ATOM 5727 O OD1 . ASP D 2 90 ? -26.024 24.480 12.079 1.00 31.12 ? 86 ASP J OD1 1 ATOM 5728 O OD2 . ASP D 2 90 ? -23.975 24.297 12.681 1.00 28.85 ? 86 ASP J OD2 1 ATOM 5729 N N . THR D 2 91 ? -24.758 29.551 13.752 1.00 17.10 ? 87 THR J N 1 ATOM 5730 C CA . THR D 2 91 ? -24.780 30.733 14.577 1.00 14.57 ? 87 THR J CA 1 ATOM 5731 C C . THR D 2 91 ? -26.118 31.424 14.399 1.00 12.02 ? 87 THR J C 1 ATOM 5732 O O . THR D 2 91 ? -26.402 31.938 13.320 1.00 14.59 ? 87 THR J O 1 ATOM 5733 C CB . THR D 2 91 ? -23.544 31.520 14.110 1.00 19.94 ? 87 THR J CB 1 ATOM 5734 O OG1 . THR D 2 91 ? -22.518 30.919 14.899 1.00 21.48 ? 87 THR J OG1 1 ATOM 5735 C CG2 . THR D 2 91 ? -23.569 33.043 14.271 1.00 26.69 ? 87 THR J CG2 1 ATOM 5736 N N . ALA D 2 92 ? -26.980 31.454 15.397 1.00 10.85 ? 88 ALA J N 1 ATOM 5737 C CA . ALA D 2 92 ? -28.326 31.950 15.166 1.00 11.08 ? 88 ALA J CA 1 ATOM 5738 C C . ALA D 2 92 ? -29.052 32.070 16.477 1.00 9.29 ? 88 ALA J C 1 ATOM 5739 O O . ALA D 2 92 ? -28.491 31.611 17.473 1.00 11.84 ? 88 ALA J O 1 ATOM 5740 C CB . ALA D 2 92 ? -29.120 30.977 14.299 1.00 4.36 ? 88 ALA J CB 1 ATOM 5741 N N . ILE D 2 93 ? -30.227 32.708 16.530 1.00 5.85 ? 89 ILE J N 1 ATOM 5742 C CA . ILE D 2 93 ? -31.071 32.655 17.724 1.00 14.18 ? 89 ILE J CA 1 ATOM 5743 C C . ILE D 2 93 ? -31.905 31.379 17.509 1.00 17.42 ? 89 ILE J C 1 ATOM 5744 O O . ILE D 2 93 ? -32.444 31.215 16.401 1.00 25.49 ? 89 ILE J O 1 ATOM 5745 C CB . ILE D 2 93 ? -32.057 33.845 17.824 1.00 15.26 ? 89 ILE J CB 1 ATOM 5746 C CG1 . ILE D 2 93 ? -31.351 35.166 17.753 1.00 18.06 ? 89 ILE J CG1 1 ATOM 5747 C CG2 . ILE D 2 93 ? -32.744 33.825 19.166 1.00 13.03 ? 89 ILE J CG2 1 ATOM 5748 C CD1 . ILE D 2 93 ? -32.382 36.306 17.534 1.00 19.98 ? 89 ILE J CD1 1 ATOM 5749 N N . TYR D 2 94 ? -32.026 30.464 18.490 1.00 14.87 ? 90 TYR J N 1 ATOM 5750 C CA . TYR D 2 94 ? -32.821 29.244 18.395 1.00 7.30 ? 90 TYR J CA 1 ATOM 5751 C C . TYR D 2 94 ? -34.075 29.416 19.223 1.00 8.68 ? 90 TYR J C 1 ATOM 5752 O O . TYR D 2 94 ? -34.007 29.582 20.455 1.00 4.41 ? 90 TYR J O 1 ATOM 5753 C CB . TYR D 2 94 ? -32.049 28.033 18.919 1.00 2.00 ? 90 TYR J CB 1 ATOM 5754 C CG . TYR D 2 94 ? -31.054 27.568 17.884 1.00 5.55 ? 90 TYR J CG 1 ATOM 5755 C CD1 . TYR D 2 94 ? -29.867 28.253 17.768 1.00 10.04 ? 90 TYR J CD1 1 ATOM 5756 C CD2 . TYR D 2 94 ? -31.334 26.511 17.022 1.00 10.49 ? 90 TYR J CD2 1 ATOM 5757 C CE1 . TYR D 2 94 ? -28.948 27.908 16.804 1.00 13.01 ? 90 TYR J CE1 1 ATOM 5758 C CE2 . TYR D 2 94 ? -30.421 26.153 16.046 1.00 9.60 ? 90 TYR J CE2 1 ATOM 5759 C CZ . TYR D 2 94 ? -29.228 26.868 15.956 1.00 16.64 ? 90 TYR J CZ 1 ATOM 5760 O OH . TYR D 2 94 ? -28.262 26.542 15.027 1.00 18.60 ? 90 TYR J OH 1 ATOM 5761 N N . TYR D 2 95 ? -35.194 29.478 18.501 1.00 3.97 ? 91 TYR J N 1 ATOM 5762 C CA . TYR D 2 95 ? -36.508 29.515 19.115 1.00 10.91 ? 91 TYR J CA 1 ATOM 5763 C C . TYR D 2 95 ? -37.085 28.137 19.324 1.00 17.28 ? 91 TYR J C 1 ATOM 5764 O O . TYR D 2 95 ? -36.797 27.254 18.503 1.00 21.91 ? 91 TYR J O 1 ATOM 5765 C CB . TYR D 2 95 ? -37.535 30.206 18.274 1.00 7.17 ? 91 TYR J CB 1 ATOM 5766 C CG . TYR D 2 95 ? -37.145 31.629 18.097 1.00 11.23 ? 91 TYR J CG 1 ATOM 5767 C CD1 . TYR D 2 95 ? -37.337 32.541 19.118 1.00 8.86 ? 91 TYR J CD1 1 ATOM 5768 C CD2 . TYR D 2 95 ? -36.569 31.965 16.915 1.00 8.66 ? 91 TYR J CD2 1 ATOM 5769 C CE1 . TYR D 2 95 ? -36.950 33.830 18.914 1.00 9.66 ? 91 TYR J CE1 1 ATOM 5770 C CE2 . TYR D 2 95 ? -36.181 33.260 16.715 1.00 13.01 ? 91 TYR J CE2 1 ATOM 5771 C CZ . TYR D 2 95 ? -36.364 34.181 17.713 1.00 14.02 ? 91 TYR J CZ 1 ATOM 5772 O OH . TYR D 2 95 ? -35.968 35.494 17.484 1.00 24.38 ? 91 TYR J OH 1 ATOM 5773 N N . CYS D 2 96 ? -37.884 27.867 20.355 1.00 17.85 ? 92 CYS J N 1 ATOM 5774 C CA . CYS D 2 96 ? -38.630 26.621 20.285 1.00 14.54 ? 92 CYS J CA 1 ATOM 5775 C C . CYS D 2 96 ? -40.059 27.087 20.068 1.00 12.79 ? 92 CYS J C 1 ATOM 5776 O O . CYS D 2 96 ? -40.407 28.197 20.493 1.00 17.96 ? 92 CYS J O 1 ATOM 5777 C CB . CYS D 2 96 ? -38.484 25.809 21.560 1.00 9.25 ? 92 CYS J CB 1 ATOM 5778 S SG . CYS D 2 96 ? -39.627 26.085 22.899 1.00 15.21 ? 92 CYS J SG 1 ATOM 5779 N N . THR D 2 97 ? -40.864 26.411 19.270 1.00 10.09 ? 93 THR J N 1 ATOM 5780 C CA . THR D 2 97 ? -42.218 26.856 19.080 1.00 7.15 ? 93 THR J CA 1 ATOM 5781 C C . THR D 2 97 ? -43.155 25.753 19.481 1.00 6.06 ? 93 THR J C 1 ATOM 5782 O O . THR D 2 97 ? -42.794 24.650 19.872 1.00 9.37 ? 93 THR J O 1 ATOM 5783 C CB . THR D 2 97 ? -42.466 27.178 17.655 1.00 2.00 ? 93 THR J CB 1 ATOM 5784 O OG1 . THR D 2 97 ? -42.215 25.987 16.944 1.00 12.85 ? 93 THR J OG1 1 ATOM 5785 C CG2 . THR D 2 97 ? -41.584 28.247 17.151 1.00 9.12 ? 93 THR J CG2 1 ATOM 5786 N N . ARG D 2 98 ? -44.396 26.074 19.301 1.00 6.53 ? 94 ARG J N 1 ATOM 5787 C CA . ARG D 2 98 ? -45.427 25.149 19.542 1.00 8.17 ? 94 ARG J CA 1 ATOM 5788 C C . ARG D 2 98 ? -46.080 25.079 18.184 1.00 14.73 ? 94 ARG J C 1 ATOM 5789 O O . ARG D 2 98 ? -46.200 26.112 17.466 1.00 16.34 ? 94 ARG J O 1 ATOM 5790 C CB . ARG D 2 98 ? -46.300 25.732 20.544 1.00 7.86 ? 94 ARG J CB 1 ATOM 5791 C CG . ARG D 2 98 ? -47.094 24.594 20.994 1.00 17.08 ? 94 ARG J CG 1 ATOM 5792 C CD . ARG D 2 98 ? -48.121 25.228 21.831 1.00 24.51 ? 94 ARG J CD 1 ATOM 5793 N NE . ARG D 2 98 ? -49.157 25.754 20.982 1.00 24.20 ? 94 ARG J NE 1 ATOM 5794 C CZ . ARG D 2 98 ? -50.325 26.081 21.511 1.00 24.71 ? 94 ARG J CZ 1 ATOM 5795 N NH1 . ARG D 2 98 ? -50.623 25.790 22.802 1.00 21.94 ? 94 ARG J NH1 1 ATOM 5796 N NH2 . ARG D 2 98 ? -51.198 26.671 20.698 1.00 17.77 ? 94 ARG J NH2 1 ATOM 5797 N N . TYR D 2 99 ? -46.436 23.822 17.872 1.00 16.87 ? 95 TYR J N 1 ATOM 5798 C CA . TYR D 2 99 ? -47.084 23.473 16.614 1.00 19.17 ? 95 TYR J CA 1 ATOM 5799 C C . TYR D 2 99 ? -48.570 23.470 16.831 1.00 18.01 ? 95 TYR J C 1 ATOM 5800 O O . TYR D 2 99 ? -48.953 23.065 17.933 1.00 22.41 ? 95 TYR J O 1 ATOM 5801 C CB . TYR D 2 99 ? -46.628 22.099 16.188 1.00 19.34 ? 95 TYR J CB 1 ATOM 5802 C CG . TYR D 2 99 ? -45.696 22.038 14.979 1.00 20.05 ? 95 TYR J CG 1 ATOM 5803 C CD1 . TYR D 2 99 ? -46.194 22.413 13.741 1.00 13.25 ? 95 TYR J CD1 1 ATOM 5804 C CD2 . TYR D 2 99 ? -44.385 21.558 15.116 1.00 17.87 ? 95 TYR J CD2 1 ATOM 5805 C CE1 . TYR D 2 99 ? -45.373 22.287 12.634 1.00 21.56 ? 95 TYR J CE1 1 ATOM 5806 C CE2 . TYR D 2 99 ? -43.558 21.439 14.005 1.00 17.60 ? 95 TYR J CE2 1 ATOM 5807 C CZ . TYR D 2 99 ? -44.071 21.806 12.768 1.00 24.50 ? 95 TYR J CZ 1 ATOM 5808 O OH . TYR D 2 99 ? -43.306 21.701 11.619 1.00 30.38 ? 95 TYR J OH 1 ATOM 5809 N N . SER D 2 100 ? -49.444 23.916 15.923 1.00 21.92 ? 96 SER J N 1 ATOM 5810 C CA . SER D 2 100 ? -50.872 23.791 16.226 1.00 31.98 ? 96 SER J CA 1 ATOM 5811 C C . SER D 2 100 ? -51.371 22.355 16.086 1.00 34.12 ? 96 SER J C 1 ATOM 5812 O O . SER D 2 100 ? -50.640 21.479 15.625 1.00 33.67 ? 96 SER J O 1 ATOM 5813 C CB . SER D 2 100 ? -51.716 24.711 15.307 1.00 32.74 ? 96 SER J CB 1 ATOM 5814 O OG . SER D 2 100 ? -51.184 24.850 14.005 1.00 34.62 ? 96 SER J OG 1 ATOM 5815 N N . SER D 2 101 ? -52.631 22.088 16.429 1.00 40.53 ? 97 SER J N 1 ATOM 5816 C CA . SER D 2 101 ? -53.215 20.763 16.267 1.00 46.42 ? 97 SER J CA 1 ATOM 5817 C C . SER D 2 101 ? -52.956 20.139 14.912 1.00 46.19 ? 97 SER J C 1 ATOM 5818 O O . SER D 2 101 ? -52.421 19.036 14.917 1.00 49.36 ? 97 SER J O 1 ATOM 5819 C CB . SER D 2 101 ? -54.710 20.781 16.442 1.00 51.40 ? 97 SER J CB 1 ATOM 5820 O OG . SER D 2 101 ? -55.099 21.150 17.761 1.00 64.99 ? 97 SER J OG 1 ATOM 5821 N N . ASP D 2 102 ? -53.290 20.754 13.761 1.00 36.75 ? 98 ASP J N 1 ATOM 5822 C CA . ASP D 2 102 ? -52.905 20.161 12.488 1.00 31.94 ? 98 ASP J CA 1 ATOM 5823 C C . ASP D 2 102 ? -51.427 20.461 12.526 1.00 28.09 ? 98 ASP J C 1 ATOM 5824 O O . ASP D 2 102 ? -51.080 21.638 12.390 1.00 23.16 ? 98 ASP J O 1 ATOM 5825 C CB . ASP D 2 102 ? -53.406 20.876 11.270 1.00 39.51 ? 98 ASP J CB 1 ATOM 5826 C CG . ASP D 2 102 ? -54.753 21.565 11.325 1.00 47.10 ? 98 ASP J CG 1 ATOM 5827 O OD1 . ASP D 2 102 ? -55.746 20.890 11.623 1.00 52.57 ? 98 ASP J OD1 1 ATOM 5828 O OD2 . ASP D 2 102 ? -54.785 22.771 11.037 1.00 47.74 ? 98 ASP J OD2 1 ATOM 5829 N N . PRO D 2 103 ? -50.505 19.559 12.802 1.00 27.49 ? 99 PRO J N 1 ATOM 5830 C CA . PRO D 2 103 ? -49.211 19.962 13.278 1.00 28.47 ? 99 PRO J CA 1 ATOM 5831 C C . PRO D 2 103 ? -48.433 20.213 12.008 1.00 26.99 ? 99 PRO J C 1 ATOM 5832 O O . PRO D 2 103 ? -47.644 19.369 11.588 1.00 25.88 ? 99 PRO J O 1 ATOM 5833 C CB . PRO D 2 103 ? -48.746 18.787 14.125 1.00 28.90 ? 99 PRO J CB 1 ATOM 5834 C CG . PRO D 2 103 ? -49.907 17.806 14.107 1.00 30.65 ? 99 PRO J CG 1 ATOM 5835 C CD . PRO D 2 103 ? -50.613 18.114 12.789 1.00 25.99 ? 99 PRO J CD 1 ATOM 5836 N N . PHE D 2 104 ? -48.719 21.348 11.359 1.00 29.59 ? 100 PHE J N 1 ATOM 5837 C CA . PHE D 2 104 ? -48.089 21.719 10.104 1.00 39.68 ? 100 PHE J CA 1 ATOM 5838 C C . PHE D 2 104 ? -47.720 23.220 10.005 1.00 39.74 ? 100 PHE J C 1 ATOM 5839 O O . PHE D 2 104 ? -47.177 23.674 8.988 1.00 39.34 ? 100 PHE J O 1 ATOM 5840 C CB . PHE D 2 104 ? -49.054 21.256 8.953 1.00 45.83 ? 100 PHE J CB 1 ATOM 5841 C CG . PHE D 2 104 ? -49.431 19.752 8.991 1.00 47.41 ? 100 PHE J CG 1 ATOM 5842 C CD1 . PHE D 2 104 ? -48.462 18.765 8.828 1.00 48.42 ? 100 PHE J CD1 1 ATOM 5843 C CD2 . PHE D 2 104 ? -50.714 19.360 9.307 1.00 42.54 ? 100 PHE J CD2 1 ATOM 5844 C CE1 . PHE D 2 104 ? -48.771 17.430 9.000 1.00 45.31 ? 100 PHE J CE1 1 ATOM 5845 C CE2 . PHE D 2 104 ? -51.012 18.032 9.472 1.00 40.34 ? 100 PHE J CE2 1 ATOM 5846 C CZ . PHE D 2 104 ? -50.050 17.064 9.325 1.00 40.94 ? 100 PHE J CZ 1 ATOM 5847 N N . TYR D 2 105 B -47.957 24.012 11.072 1.00 33.97 ? 100 TYR J N 1 ATOM 5848 C CA . TYR D 2 105 B -47.644 25.434 11.144 1.00 25.60 ? 100 TYR J CA 1 ATOM 5849 C C . TYR D 2 105 B -47.489 25.812 12.608 1.00 25.47 ? 100 TYR J C 1 ATOM 5850 O O . TYR D 2 105 B -48.049 25.096 13.457 1.00 28.32 ? 100 TYR J O 1 ATOM 5851 C CB . TYR D 2 105 B -48.762 26.229 10.509 1.00 28.78 ? 100 TYR J CB 1 ATOM 5852 C CG . TYR D 2 105 B -50.164 26.284 11.138 1.00 29.54 ? 100 TYR J CG 1 ATOM 5853 C CD1 . TYR D 2 105 B -51.157 25.385 10.804 1.00 33.44 ? 100 TYR J CD1 1 ATOM 5854 C CD2 . TYR D 2 105 B -50.489 27.311 11.983 1.00 28.84 ? 100 TYR J CD2 1 ATOM 5855 C CE1 . TYR D 2 105 B -52.449 25.518 11.303 1.00 31.80 ? 100 TYR J CE1 1 ATOM 5856 C CE2 . TYR D 2 105 B -51.766 27.449 12.478 1.00 30.51 ? 100 TYR J CE2 1 ATOM 5857 C CZ . TYR D 2 105 B -52.745 26.561 12.140 1.00 31.51 ? 100 TYR J CZ 1 ATOM 5858 O OH . TYR D 2 105 B -54.016 26.745 12.642 1.00 33.09 ? 100 TYR J OH 1 ATOM 5859 N N . PHE D 2 106 C -46.760 26.881 12.968 1.00 24.26 ? 100 PHE J N 1 ATOM 5860 C CA . PHE D 2 106 C -46.510 27.191 14.392 1.00 24.63 ? 100 PHE J CA 1 ATOM 5861 C C . PHE D 2 106 C -47.387 28.340 14.888 1.00 22.82 ? 100 PHE J C 1 ATOM 5862 O O . PHE D 2 106 C -47.720 29.280 14.135 1.00 14.26 ? 100 PHE J O 1 ATOM 5863 C CB . PHE D 2 106 C -45.059 27.624 14.688 1.00 21.90 ? 100 PHE J CB 1 ATOM 5864 C CG . PHE D 2 106 C -44.031 26.992 13.774 1.00 19.20 ? 100 PHE J CG 1 ATOM 5865 C CD1 . PHE D 2 106 C -43.542 25.724 14.014 1.00 17.56 ? 100 PHE J CD1 1 ATOM 5866 C CD2 . PHE D 2 106 C -43.607 27.688 12.662 1.00 16.35 ? 100 PHE J CD2 1 ATOM 5867 C CE1 . PHE D 2 106 C -42.632 25.169 13.122 1.00 19.86 ? 100 PHE J CE1 1 ATOM 5868 C CE2 . PHE D 2 106 C -42.698 27.108 11.797 1.00 16.72 ? 100 PHE J CE2 1 ATOM 5869 C CZ . PHE D 2 106 C -42.206 25.850 12.009 1.00 16.18 ? 100 PHE J CZ 1 ATOM 5870 N N . ASP D 2 107 ? -47.743 28.311 16.171 1.00 18.15 ? 101 ASP J N 1 ATOM 5871 C CA . ASP D 2 107 ? -48.605 29.373 16.664 1.00 18.39 ? 101 ASP J CA 1 ATOM 5872 C C . ASP D 2 107 ? -48.071 30.182 17.836 1.00 13.75 ? 101 ASP J C 1 ATOM 5873 O O . ASP D 2 107 ? -48.381 31.363 17.970 1.00 12.59 ? 101 ASP J O 1 ATOM 5874 C CB . ASP D 2 107 ? -49.960 28.759 17.000 1.00 24.69 ? 101 ASP J CB 1 ATOM 5875 C CG . ASP D 2 107 ? -50.009 27.560 17.947 1.00 30.23 ? 101 ASP J CG 1 ATOM 5876 O OD1 . ASP D 2 107 ? -49.067 27.342 18.705 1.00 30.04 ? 101 ASP J OD1 1 ATOM 5877 O OD2 . ASP D 2 107 ? -51.025 26.859 17.944 1.00 31.35 ? 101 ASP J OD2 1 ATOM 5878 N N . TYR D 2 108 ? -47.254 29.573 18.674 1.00 6.23 ? 102 TYR J N 1 ATOM 5879 C CA . TYR D 2 108 ? -46.642 30.277 19.752 1.00 15.38 ? 102 TYR J CA 1 ATOM 5880 C C . TYR D 2 108 ? -45.126 30.106 19.699 1.00 19.31 ? 102 TYR J C 1 ATOM 5881 O O . TYR D 2 108 ? -44.666 28.972 19.564 1.00 20.69 ? 102 TYR J O 1 ATOM 5882 C CB . TYR D 2 108 ? -47.193 29.749 21.044 1.00 25.40 ? 102 TYR J CB 1 ATOM 5883 C CG . TYR D 2 108 ? -48.577 30.302 21.342 1.00 34.13 ? 102 TYR J CG 1 ATOM 5884 C CD1 . TYR D 2 108 ? -48.764 31.503 22.009 1.00 31.22 ? 102 TYR J CD1 1 ATOM 5885 C CD2 . TYR D 2 108 ? -49.670 29.584 20.924 1.00 42.00 ? 102 TYR J CD2 1 ATOM 5886 C CE1 . TYR D 2 108 ? -50.048 31.971 22.238 1.00 36.76 ? 102 TYR J CE1 1 ATOM 5887 C CE2 . TYR D 2 108 ? -50.953 30.051 21.152 1.00 45.28 ? 102 TYR J CE2 1 ATOM 5888 C CZ . TYR D 2 108 ? -51.142 31.244 21.807 1.00 40.53 ? 102 TYR J CZ 1 ATOM 5889 O OH . TYR D 2 108 ? -52.438 31.701 21.969 1.00 40.14 ? 102 TYR J OH 1 ATOM 5890 N N . TRP D 2 109 ? -44.313 31.176 19.769 1.00 20.96 ? 103 TRP J N 1 ATOM 5891 C CA . TRP D 2 109 ? -42.862 31.081 19.717 1.00 15.51 ? 103 TRP J CA 1 ATOM 5892 C C . TRP D 2 109 ? -42.297 31.492 21.077 1.00 17.41 ? 103 TRP J C 1 ATOM 5893 O O . TRP D 2 109 ? -42.795 32.401 21.751 1.00 18.86 ? 103 TRP J O 1 ATOM 5894 C CB . TRP D 2 109 ? -42.267 32.017 18.702 1.00 8.28 ? 103 TRP J CB 1 ATOM 5895 C CG . TRP D 2 109 ? -42.692 31.874 17.261 1.00 7.30 ? 103 TRP J CG 1 ATOM 5896 C CD1 . TRP D 2 109 ? -44.004 31.918 16.882 1.00 8.71 ? 103 TRP J CD1 1 ATOM 5897 C CD2 . TRP D 2 109 ? -41.836 31.718 16.192 1.00 12.03 ? 103 TRP J CD2 1 ATOM 5898 N NE1 . TRP D 2 109 ? -43.982 31.791 15.574 1.00 11.38 ? 103 TRP J NE1 1 ATOM 5899 C CE2 . TRP D 2 109 ? -42.725 31.671 15.123 1.00 9.24 ? 103 TRP J CE2 1 ATOM 5900 C CE3 . TRP D 2 109 ? -40.466 31.623 15.988 1.00 13.38 ? 103 TRP J CE3 1 ATOM 5901 C CZ2 . TRP D 2 109 ? -42.275 31.530 13.832 1.00 10.55 ? 103 TRP J CZ2 1 ATOM 5902 C CZ3 . TRP D 2 109 ? -40.014 31.486 14.687 1.00 14.86 ? 103 TRP J CZ3 1 ATOM 5903 C CH2 . TRP D 2 109 ? -40.904 31.439 13.628 1.00 17.27 ? 103 TRP J CH2 1 ATOM 5904 N N . GLY D 2 110 ? -41.286 30.754 21.515 1.00 18.84 ? 104 GLY J N 1 ATOM 5905 C CA . GLY D 2 110 ? -40.581 31.052 22.737 1.00 15.75 ? 104 GLY J CA 1 ATOM 5906 C C . GLY D 2 110 ? -39.713 32.277 22.499 1.00 20.96 ? 104 GLY J C 1 ATOM 5907 O O . GLY D 2 110 ? -39.668 32.836 21.387 1.00 21.55 ? 104 GLY J O 1 ATOM 5908 N N . GLN D 2 111 ? -38.953 32.565 23.570 1.00 19.61 ? 105 GLN J N 1 ATOM 5909 C CA . GLN D 2 111 ? -38.091 33.735 23.675 1.00 22.87 ? 105 GLN J CA 1 ATOM 5910 C C . GLN D 2 111 ? -36.705 33.731 23.017 1.00 22.89 ? 105 GLN J C 1 ATOM 5911 O O . GLN D 2 111 ? -36.155 34.788 22.730 1.00 19.11 ? 105 GLN J O 1 ATOM 5912 C CB . GLN D 2 111 ? -37.987 34.049 25.169 1.00 29.60 ? 105 GLN J CB 1 ATOM 5913 C CG . GLN D 2 111 ? -39.295 34.639 25.723 1.00 40.33 ? 105 GLN J CG 1 ATOM 5914 C CD . GLN D 2 111 ? -39.721 36.000 25.137 1.00 48.72 ? 105 GLN J CD 1 ATOM 5915 O OE1 . GLN D 2 111 ? -39.004 36.700 24.422 1.00 53.38 ? 105 GLN J OE1 1 ATOM 5916 N NE2 . GLN D 2 111 ? -40.900 36.518 25.442 1.00 52.39 ? 105 GLN J NE2 1 ATOM 5917 N N . GLY D 2 112 ? -36.092 32.570 22.792 1.00 22.22 ? 106 GLY J N 1 ATOM 5918 C CA . GLY D 2 112 ? -34.861 32.434 22.013 1.00 24.70 ? 106 GLY J CA 1 ATOM 5919 C C . GLY D 2 112 ? -33.513 32.307 22.741 1.00 22.45 ? 106 GLY J C 1 ATOM 5920 O O . GLY D 2 112 ? -33.303 32.982 23.742 1.00 24.35 ? 106 GLY J O 1 ATOM 5921 N N . THR D 2 113 ? -32.599 31.420 22.303 1.00 15.51 ? 107 THR J N 1 ATOM 5922 C CA . THR D 2 113 ? -31.242 31.443 22.809 1.00 13.53 ? 107 THR J CA 1 ATOM 5923 C C . THR D 2 113 ? -30.257 31.485 21.657 1.00 18.75 ? 107 THR J C 1 ATOM 5924 O O . THR D 2 113 ? -30.362 30.765 20.662 1.00 15.63 ? 107 THR J O 1 ATOM 5925 C CB . THR D 2 113 ? -30.898 30.247 23.637 1.00 12.53 ? 107 THR J CB 1 ATOM 5926 O OG1 . THR D 2 113 ? -31.745 29.171 23.266 1.00 15.08 ? 107 THR J OG1 1 ATOM 5927 C CG2 . THR D 2 113 ? -30.940 30.638 25.089 1.00 15.78 ? 107 THR J CG2 1 ATOM 5928 N N . THR D 2 114 ? -29.324 32.402 21.844 1.00 22.57 ? 108 THR J N 1 ATOM 5929 C CA . THR D 2 114 ? -28.278 32.767 20.917 1.00 24.45 ? 108 THR J CA 1 ATOM 5930 C C . THR D 2 114 ? -27.194 31.698 20.812 1.00 21.64 ? 108 THR J C 1 ATOM 5931 O O . THR D 2 114 ? -26.625 31.345 21.845 1.00 25.61 ? 108 THR J O 1 ATOM 5932 C CB . THR D 2 114 ? -27.751 34.127 21.440 1.00 29.46 ? 108 THR J CB 1 ATOM 5933 O OG1 . THR D 2 114 ? -28.867 34.945 21.817 1.00 28.65 ? 108 THR J OG1 1 ATOM 5934 C CG2 . THR D 2 114 ? -26.974 34.868 20.375 1.00 36.98 ? 108 THR J CG2 1 ATOM 5935 N N . LEU D 2 115 ? -26.855 31.115 19.668 1.00 19.10 ? 109 LEU J N 1 ATOM 5936 C CA . LEU D 2 115 ? -25.763 30.153 19.609 1.00 17.79 ? 109 LEU J CA 1 ATOM 5937 C C . LEU D 2 115 ? -24.725 30.861 18.763 1.00 17.56 ? 109 LEU J C 1 ATOM 5938 O O . LEU D 2 115 ? -25.052 31.332 17.655 1.00 15.61 ? 109 LEU J O 1 ATOM 5939 C CB . LEU D 2 115 ? -26.131 28.891 18.874 1.00 15.33 ? 109 LEU J CB 1 ATOM 5940 C CG . LEU D 2 115 ? -25.718 27.483 19.282 1.00 14.42 ? 109 LEU J CG 1 ATOM 5941 C CD1 . LEU D 2 115 ? -25.581 26.716 17.994 1.00 15.31 ? 109 LEU J CD1 1 ATOM 5942 C CD2 . LEU D 2 115 ? -24.390 27.377 19.945 1.00 15.48 ? 109 LEU J CD2 1 ATOM 5943 N N . THR D 2 116 ? -23.492 30.923 19.267 1.00 14.92 ? 110 THR J N 1 ATOM 5944 C CA . THR D 2 116 ? -22.387 31.536 18.562 1.00 12.86 ? 110 THR J CA 1 ATOM 5945 C C . THR D 2 116 ? -21.320 30.465 18.490 1.00 12.18 ? 110 THR J C 1 ATOM 5946 O O . THR D 2 116 ? -20.802 29.987 19.506 1.00 11.76 ? 110 THR J O 1 ATOM 5947 C CB . THR D 2 116 ? -21.876 32.741 19.339 1.00 18.54 ? 110 THR J CB 1 ATOM 5948 O OG1 . THR D 2 116 ? -22.979 33.426 19.972 1.00 16.06 ? 110 THR J OG1 1 ATOM 5949 C CG2 . THR D 2 116 ? -21.132 33.660 18.370 1.00 19.54 ? 110 THR J CG2 1 ATOM 5950 N N . VAL D 2 117 ? -21.026 30.074 17.259 1.00 12.86 ? 111 VAL J N 1 ATOM 5951 C CA . VAL D 2 117 ? -20.107 28.997 16.981 1.00 16.11 ? 111 VAL J CA 1 ATOM 5952 C C . VAL D 2 117 ? -18.901 29.775 16.505 1.00 19.02 ? 111 VAL J C 1 ATOM 5953 O O . VAL D 2 117 ? -18.962 30.343 15.406 1.00 14.51 ? 111 VAL J O 1 ATOM 5954 C CB . VAL D 2 117 ? -20.593 28.099 15.827 1.00 20.52 ? 111 VAL J CB 1 ATOM 5955 C CG1 . VAL D 2 117 ? -19.730 26.883 15.813 1.00 24.59 ? 111 VAL J CG1 1 ATOM 5956 C CG2 . VAL D 2 117 ? -22.005 27.612 15.991 1.00 23.30 ? 111 VAL J CG2 1 ATOM 5957 N N . SER D 2 118 ? -17.826 29.922 17.271 1.00 25.05 ? 112 SER J N 1 ATOM 5958 C CA . SER D 2 118 ? -16.662 30.646 16.777 1.00 30.49 ? 112 SER J CA 1 ATOM 5959 C C . SER D 2 118 ? -15.415 30.244 17.563 1.00 33.84 ? 112 SER J C 1 ATOM 5960 O O . SER D 2 118 ? -15.485 29.761 18.700 1.00 33.77 ? 112 SER J O 1 ATOM 5961 C CB . SER D 2 118 ? -16.919 32.154 16.893 1.00 27.43 ? 112 SER J CB 1 ATOM 5962 O OG . SER D 2 118 ? -15.972 32.895 16.150 1.00 26.95 ? 112 SER J OG 1 ATOM 5963 N N . SER D 2 119 ? -14.264 30.379 16.884 1.00 31.16 ? 113 SER J N 1 ATOM 5964 C CA . SER D 2 119 ? -12.970 30.027 17.469 1.00 26.78 ? 113 SER J CA 1 ATOM 5965 C C . SER D 2 119 ? -12.427 31.119 18.362 1.00 23.97 ? 113 SER J C 1 ATOM 5966 O O . SER D 2 119 ? -11.428 30.941 19.046 1.00 25.80 ? 113 SER J O 1 ATOM 5967 C CB . SER D 2 119 ? -11.974 29.745 16.366 1.00 24.68 ? 113 SER J CB 1 ATOM 5968 O OG . SER D 2 119 ? -12.153 30.589 15.223 1.00 25.65 ? 113 SER J OG 1 ATOM 5969 N N . ALA D 2 120 ? -13.073 32.278 18.305 1.00 19.86 ? 114 ALA J N 1 ATOM 5970 C CA . ALA D 2 120 ? -12.716 33.422 19.109 1.00 22.33 ? 114 ALA J CA 1 ATOM 5971 C C . ALA D 2 120 ? -12.823 33.100 20.577 1.00 23.50 ? 114 ALA J C 1 ATOM 5972 O O . ALA D 2 120 ? -13.459 32.113 20.932 1.00 23.01 ? 114 ALA J O 1 ATOM 5973 C CB . ALA D 2 120 ? -13.657 34.588 18.829 1.00 25.65 ? 114 ALA J CB 1 ATOM 5974 N N . LYS D 2 121 ? -12.260 33.939 21.446 1.00 27.27 ? 115 LYS J N 1 ATOM 5975 C CA . LYS D 2 121 ? -12.353 33.700 22.882 1.00 24.27 ? 115 LYS J CA 1 ATOM 5976 C C . LYS D 2 121 ? -13.270 34.751 23.467 1.00 19.76 ? 115 LYS J C 1 ATOM 5977 O O . LYS D 2 121 ? -13.512 35.811 22.895 1.00 23.62 ? 115 LYS J O 1 ATOM 5978 C CB . LYS D 2 121 ? -11.025 33.854 23.595 1.00 28.56 ? 115 LYS J CB 1 ATOM 5979 C CG . LYS D 2 121 ? -9.791 33.171 23.036 1.00 34.37 ? 115 LYS J CG 1 ATOM 5980 C CD . LYS D 2 121 ? -9.467 31.822 23.639 1.00 36.39 ? 115 LYS J CD 1 ATOM 5981 C CE . LYS D 2 121 ? -8.021 31.556 23.233 1.00 34.59 ? 115 LYS J CE 1 ATOM 5982 N NZ . LYS D 2 121 ? -7.543 30.329 23.835 1.00 39.51 ? 115 LYS J NZ 1 ATOM 5983 N N . THR D 2 122 ? -13.778 34.440 24.637 1.00 19.87 ? 116 THR J N 1 ATOM 5984 C CA . THR D 2 122 ? -14.577 35.328 25.462 1.00 19.08 ? 116 THR J CA 1 ATOM 5985 C C . THR D 2 122 ? -13.658 36.507 25.791 1.00 23.30 ? 116 THR J C 1 ATOM 5986 O O . THR D 2 122 ? -12.528 36.266 26.218 1.00 33.65 ? 116 THR J O 1 ATOM 5987 C CB . THR D 2 122 ? -14.957 34.488 26.675 1.00 17.64 ? 116 THR J CB 1 ATOM 5988 O OG1 . THR D 2 122 ? -15.657 33.351 26.152 1.00 22.92 ? 116 THR J OG1 1 ATOM 5989 C CG2 . THR D 2 122 ? -15.771 35.223 27.692 1.00 17.66 ? 116 THR J CG2 1 ATOM 5990 N N . THR D 2 123 ? -13.994 37.778 25.601 1.00 23.27 ? 117 THR J N 1 ATOM 5991 C CA . THR D 2 123 ? -13.090 38.882 25.902 1.00 15.25 ? 117 THR J CA 1 ATOM 5992 C C . THR D 2 123 ? -13.975 39.948 26.512 1.00 9.95 ? 117 THR J C 1 ATOM 5993 O O . THR D 2 123 ? -15.114 40.134 26.069 1.00 3.69 ? 117 THR J O 1 ATOM 5994 C CB . THR D 2 123 ? -12.450 39.347 24.591 1.00 23.21 ? 117 THR J CB 1 ATOM 5995 O OG1 . THR D 2 123 ? -12.153 38.161 23.838 1.00 26.91 ? 117 THR J OG1 1 ATOM 5996 C CG2 . THR D 2 123 ? -11.184 40.157 24.811 1.00 22.05 ? 117 THR J CG2 1 ATOM 5997 N N . PRO D 2 124 ? -13.607 40.569 27.624 1.00 12.08 ? 118 PRO J N 1 ATOM 5998 C CA . PRO D 2 124 ? -14.451 41.581 28.301 1.00 14.12 ? 118 PRO J CA 1 ATOM 5999 C C . PRO D 2 124 ? -14.476 42.899 27.515 1.00 15.49 ? 118 PRO J C 1 ATOM 6000 O O . PRO D 2 124 ? -13.552 43.059 26.722 1.00 21.36 ? 118 PRO J O 1 ATOM 6001 C CB . PRO D 2 124 ? -13.824 41.665 29.670 1.00 8.97 ? 118 PRO J CB 1 ATOM 6002 C CG . PRO D 2 124 ? -12.353 41.398 29.386 1.00 8.28 ? 118 PRO J CG 1 ATOM 6003 C CD . PRO D 2 124 ? -12.369 40.300 28.333 1.00 8.62 ? 118 PRO J CD 1 ATOM 6004 N N . PRO D 2 125 ? -15.430 43.835 27.590 1.00 11.19 ? 119 PRO J N 1 ATOM 6005 C CA . PRO D 2 125 ? -15.450 45.028 26.765 1.00 11.31 ? 119 PRO J CA 1 ATOM 6006 C C . PRO D 2 125 ? -14.520 46.075 27.315 1.00 9.38 ? 119 PRO J C 1 ATOM 6007 O O . PRO D 2 125 ? -14.377 46.097 28.534 1.00 17.54 ? 119 PRO J O 1 ATOM 6008 C CB . PRO D 2 125 ? -16.903 45.464 26.782 1.00 7.65 ? 119 PRO J CB 1 ATOM 6009 C CG . PRO D 2 125 ? -17.345 45.124 28.152 1.00 2.06 ? 119 PRO J CG 1 ATOM 6010 C CD . PRO D 2 125 ? -16.689 43.749 28.299 1.00 10.41 ? 119 PRO J CD 1 ATOM 6011 N N . SER D 2 126 ? -13.844 46.907 26.532 1.00 10.68 ? 120 SER J N 1 ATOM 6012 C CA . SER D 2 126 ? -13.184 48.092 27.073 1.00 7.45 ? 120 SER J CA 1 ATOM 6013 C C . SER D 2 126 ? -14.238 49.169 26.953 1.00 4.27 ? 120 SER J C 1 ATOM 6014 O O . SER D 2 126 ? -14.909 49.227 25.931 1.00 7.65 ? 120 SER J O 1 ATOM 6015 C CB . SER D 2 126 ? -12.007 48.549 26.256 1.00 6.25 ? 120 SER J CB 1 ATOM 6016 O OG . SER D 2 126 ? -10.990 47.583 26.082 1.00 6.40 ? 120 SER J OG 1 ATOM 6017 N N . VAL D 2 127 ? -14.513 50.015 27.927 1.00 13.12 ? 121 VAL J N 1 ATOM 6018 C CA . VAL D 2 127 ? -15.540 51.012 27.698 1.00 13.85 ? 121 VAL J CA 1 ATOM 6019 C C . VAL D 2 127 ? -14.884 52.344 28.004 1.00 11.22 ? 121 VAL J C 1 ATOM 6020 O O . VAL D 2 127 ? -14.114 52.548 28.947 1.00 12.57 ? 121 VAL J O 1 ATOM 6021 C CB . VAL D 2 127 ? -16.837 50.746 28.579 1.00 16.38 ? 121 VAL J CB 1 ATOM 6022 C CG1 . VAL D 2 127 ? -17.030 49.221 28.774 1.00 17.22 ? 121 VAL J CG1 1 ATOM 6023 C CG2 . VAL D 2 127 ? -16.777 51.488 29.876 1.00 12.62 ? 121 VAL J CG2 1 ATOM 6024 N N . TYR D 2 128 ? -15.112 53.187 27.037 1.00 7.97 ? 122 TYR J N 1 ATOM 6025 C CA . TYR D 2 128 ? -14.464 54.453 27.009 1.00 6.87 ? 122 TYR J CA 1 ATOM 6026 C C . TYR D 2 128 ? -15.558 55.449 26.963 1.00 13.21 ? 122 TYR J C 1 ATOM 6027 O O . TYR D 2 128 ? -16.485 55.246 26.176 1.00 17.84 ? 122 TYR J O 1 ATOM 6028 C CB . TYR D 2 128 ? -13.723 54.601 25.796 1.00 2.54 ? 122 TYR J CB 1 ATOM 6029 C CG . TYR D 2 128 ? -12.731 53.505 25.595 1.00 8.49 ? 122 TYR J CG 1 ATOM 6030 C CD1 . TYR D 2 128 ? -11.637 53.396 26.436 1.00 4.20 ? 122 TYR J CD1 1 ATOM 6031 C CD2 . TYR D 2 128 ? -12.922 52.681 24.506 1.00 10.34 ? 122 TYR J CD2 1 ATOM 6032 C CE1 . TYR D 2 128 ? -10.678 52.448 26.157 1.00 4.46 ? 122 TYR J CE1 1 ATOM 6033 C CE2 . TYR D 2 128 ? -11.968 51.737 24.233 1.00 14.32 ? 122 TYR J CE2 1 ATOM 6034 C CZ . TYR D 2 128 ? -10.863 51.629 25.061 1.00 13.62 ? 122 TYR J CZ 1 ATOM 6035 O OH . TYR D 2 128 ? -9.911 50.667 24.769 1.00 22.32 ? 122 TYR J OH 1 ATOM 6036 N N . PRO D 2 129 ? -15.540 56.524 27.722 1.00 17.69 ? 123 PRO J N 1 ATOM 6037 C CA . PRO D 2 129 ? -16.657 57.437 27.791 1.00 20.79 ? 123 PRO J CA 1 ATOM 6038 C C . PRO D 2 129 ? -16.620 58.465 26.659 1.00 21.12 ? 123 PRO J C 1 ATOM 6039 O O . PRO D 2 129 ? -15.572 59.111 26.506 1.00 23.09 ? 123 PRO J O 1 ATOM 6040 C CB . PRO D 2 129 ? -16.475 57.949 29.197 1.00 22.87 ? 123 PRO J CB 1 ATOM 6041 C CG . PRO D 2 129 ? -14.983 58.120 29.341 1.00 19.98 ? 123 PRO J CG 1 ATOM 6042 C CD . PRO D 2 129 ? -14.416 56.967 28.533 1.00 18.23 ? 123 PRO J CD 1 ATOM 6043 N N . LEU D 2 130 ? -17.698 58.622 25.857 1.00 16.26 ? 124 LEU J N 1 ATOM 6044 C CA . LEU D 2 130 ? -17.782 59.632 24.789 1.00 12.34 ? 124 LEU J CA 1 ATOM 6045 C C . LEU D 2 130 ? -18.339 60.916 25.371 1.00 8.68 ? 124 LEU J C 1 ATOM 6046 O O . LEU D 2 130 ? -19.526 61.124 25.488 1.00 11.18 ? 124 LEU J O 1 ATOM 6047 C CB . LEU D 2 130 ? -18.707 59.200 23.682 1.00 9.17 ? 124 LEU J CB 1 ATOM 6048 C CG . LEU D 2 130 ? -18.208 58.472 22.476 1.00 9.33 ? 124 LEU J CG 1 ATOM 6049 C CD1 . LEU D 2 130 ? -16.798 57.940 22.676 1.00 8.81 ? 124 LEU J CD1 1 ATOM 6050 C CD2 . LEU D 2 130 ? -19.220 57.402 22.187 1.00 4.70 ? 124 LEU J CD2 1 ATOM 6051 N N . ALA D 2 131 ? -17.451 61.773 25.805 1.00 19.56 ? 125 ALA J N 1 ATOM 6052 C CA . ALA D 2 131 ? -17.722 63.035 26.462 1.00 20.42 ? 125 ALA J CA 1 ATOM 6053 C C . ALA D 2 131 ? -17.651 64.222 25.490 1.00 25.98 ? 125 ALA J C 1 ATOM 6054 O O . ALA D 2 131 ? -16.848 64.293 24.545 1.00 16.45 ? 125 ALA J O 1 ATOM 6055 C CB . ALA D 2 131 ? -16.700 63.229 27.594 1.00 20.87 ? 125 ALA J CB 1 ATOM 6056 N N . PRO D 2 132 ? -18.564 65.169 25.656 1.00 36.27 ? 126 PRO J N 1 ATOM 6057 C CA . PRO D 2 132 ? -18.875 66.121 24.621 1.00 41.00 ? 126 PRO J CA 1 ATOM 6058 C C . PRO D 2 132 ? -17.661 66.985 24.431 1.00 48.90 ? 126 PRO J C 1 ATOM 6059 O O . PRO D 2 132 ? -17.003 67.320 25.408 1.00 53.60 ? 126 PRO J O 1 ATOM 6060 C CB . PRO D 2 132 ? -20.086 66.777 25.182 1.00 38.15 ? 126 PRO J CB 1 ATOM 6061 C CG . PRO D 2 132 ? -19.854 66.796 26.675 1.00 33.30 ? 126 PRO J CG 1 ATOM 6062 C CD . PRO D 2 132 ? -19.275 65.451 26.904 1.00 37.55 ? 126 PRO J CD 1 ATOM 6063 N N . GLY D 2 133 ? -17.323 67.238 23.177 1.00 61.55 ? 127 GLY J N 1 ATOM 6064 C CA . GLY D 2 133 ? -16.196 68.085 22.799 1.00 71.20 ? 127 GLY J CA 1 ATOM 6065 C C . GLY D 2 133 ? -16.781 68.914 21.679 1.00 77.33 ? 127 GLY J C 1 ATOM 6066 O O . GLY D 2 133 ? -17.148 70.088 21.828 1.00 81.13 ? 127 GLY J O 1 ATOM 6067 N N . SER D 2 134 ? -16.952 68.143 20.602 1.00 78.97 ? 128 SER J N 1 ATOM 6068 C CA . SER D 2 134 ? -17.704 68.534 19.423 1.00 82.25 ? 128 SER J CA 1 ATOM 6069 C C . SER D 2 134 ? -17.366 69.885 18.796 1.00 82.30 ? 128 SER J C 1 ATOM 6070 O O . SER D 2 134 ? -16.213 70.334 18.829 1.00 79.83 ? 128 SER J O 1 ATOM 6071 C CB . SER D 2 134 ? -19.183 68.415 19.860 1.00 82.95 ? 128 SER J CB 1 ATOM 6072 O OG . SER D 2 134 ? -19.406 67.206 20.588 1.00 82.60 ? 128 SER J OG 1 ATOM 6073 N N . ALA D 2 135 ? -18.357 70.509 18.157 1.00 84.45 ? 129 ALA J N 1 ATOM 6074 C CA . ALA D 2 135 ? -18.177 71.855 17.679 1.00 92.49 ? 129 ALA J CA 1 ATOM 6075 C C . ALA D 2 135 ? -18.847 72.717 18.758 1.00 97.79 ? 129 ALA J C 1 ATOM 6076 O O . ALA D 2 135 ? -19.901 73.334 18.555 1.00 99.26 ? 129 ALA J O 1 ATOM 6077 C CB . ALA D 2 135 ? -18.873 72.011 16.333 1.00 92.53 ? 129 ALA J CB 1 ATOM 6078 N N . ALA D 2 136 ? -18.215 72.709 19.948 1.00 101.36 ? 130 ALA J N 1 ATOM 6079 C CA . ALA D 2 136 ? -18.644 73.405 21.163 1.00 102.05 ? 130 ALA J CA 1 ATOM 6080 C C . ALA D 2 136 ? -20.090 73.064 21.551 1.00 102.80 ? 130 ALA J C 1 ATOM 6081 O O . ALA D 2 136 ? -20.350 71.899 21.855 1.00 105.18 ? 130 ALA J O 1 ATOM 6082 C CB . ALA D 2 136 ? -18.469 74.923 20.950 1.00 99.74 ? 130 ALA J CB 1 ATOM 6083 N N . GLN D 2 137 ? -21.055 73.996 21.513 1.00 101.92 ? 133 GLN J N 1 ATOM 6084 C CA . GLN D 2 137 ? -22.468 73.808 21.838 1.00 100.21 ? 133 GLN J CA 1 ATOM 6085 C C . GLN D 2 137 ? -22.911 73.378 23.231 1.00 93.24 ? 133 GLN J C 1 ATOM 6086 O O . GLN D 2 137 ? -22.976 72.225 23.655 1.00 92.99 ? 133 GLN J O 1 ATOM 6087 C CB . GLN D 2 137 ? -23.139 72.823 20.831 1.00 106.57 ? 133 GLN J CB 1 ATOM 6088 C CG . GLN D 2 137 ? -24.675 72.675 20.964 1.00 111.17 ? 133 GLN J CG 1 ATOM 6089 C CD . GLN D 2 137 ? -25.219 71.273 21.267 1.00 112.34 ? 133 GLN J CD 1 ATOM 6090 O OE1 . GLN D 2 137 ? -26.121 70.819 20.574 1.00 115.79 ? 133 GLN J OE1 1 ATOM 6091 N NE2 . GLN D 2 137 ? -24.796 70.509 22.269 1.00 110.48 ? 133 GLN J NE2 1 ATOM 6092 N N . THR D 2 138 ? -23.319 74.397 23.948 1.00 86.93 ? 134 THR J N 1 ATOM 6093 C CA . THR D 2 138 ? -24.015 74.195 25.192 1.00 83.88 ? 134 THR J CA 1 ATOM 6094 C C . THR D 2 138 ? -25.293 74.930 24.778 1.00 85.90 ? 134 THR J C 1 ATOM 6095 O O . THR D 2 138 ? -25.301 76.167 24.690 1.00 85.94 ? 134 THR J O 1 ATOM 6096 C CB . THR D 2 138 ? -23.215 74.878 26.285 1.00 81.79 ? 134 THR J CB 1 ATOM 6097 O OG1 . THR D 2 138 ? -21.975 74.177 26.330 1.00 82.37 ? 134 THR J OG1 1 ATOM 6098 C CG2 . THR D 2 138 ? -23.903 74.866 27.646 1.00 79.75 ? 134 THR J CG2 1 ATOM 6099 N N . ASN D 2 139 ? -26.270 74.103 24.335 1.00 81.60 ? 135 ASN J N 1 ATOM 6100 C CA . ASN D 2 139 ? -27.575 74.556 23.831 1.00 71.65 ? 135 ASN J CA 1 ATOM 6101 C C . ASN D 2 139 ? -28.758 74.595 24.823 1.00 64.53 ? 135 ASN J C 1 ATOM 6102 O O . ASN D 2 139 ? -29.266 75.641 25.226 1.00 64.68 ? 135 ASN J O 1 ATOM 6103 C CB . ASN D 2 139 ? -27.954 73.676 22.639 1.00 70.21 ? 135 ASN J CB 1 ATOM 6104 C CG . ASN D 2 139 ? -29.138 74.242 21.870 1.00 73.54 ? 135 ASN J CG 1 ATOM 6105 O OD1 . ASN D 2 139 ? -29.002 75.141 21.044 1.00 73.78 ? 135 ASN J OD1 1 ATOM 6106 N ND2 . ASN D 2 139 ? -30.348 73.756 22.076 1.00 74.21 ? 135 ASN J ND2 1 ATOM 6107 N N . SER D 2 140 ? -29.152 73.426 25.299 1.00 53.62 ? 136 SER J N 1 ATOM 6108 C CA . SER D 2 140 ? -30.316 73.221 26.152 1.00 46.82 ? 136 SER J CA 1 ATOM 6109 C C . SER D 2 140 ? -30.329 71.741 26.450 1.00 42.55 ? 136 SER J C 1 ATOM 6110 O O . SER D 2 140 ? -30.622 71.262 27.532 1.00 43.76 ? 136 SER J O 1 ATOM 6111 C CB . SER D 2 140 ? -31.615 73.550 25.438 1.00 50.58 ? 136 SER J CB 1 ATOM 6112 O OG . SER D 2 140 ? -31.744 72.929 24.160 1.00 52.95 ? 136 SER J OG 1 ATOM 6113 N N . MET D 2 141 ? -29.850 71.016 25.455 1.00 40.10 ? 137 MET J N 1 ATOM 6114 C CA . MET D 2 141 ? -29.805 69.590 25.378 1.00 31.65 ? 137 MET J CA 1 ATOM 6115 C C . MET D 2 141 ? -28.360 69.272 25.023 1.00 29.02 ? 137 MET J C 1 ATOM 6116 O O . MET D 2 141 ? -27.890 69.813 24.013 1.00 30.00 ? 137 MET J O 1 ATOM 6117 C CB . MET D 2 141 ? -30.751 69.210 24.266 1.00 28.86 ? 137 MET J CB 1 ATOM 6118 C CG . MET D 2 141 ? -31.876 68.228 24.510 1.00 31.61 ? 137 MET J CG 1 ATOM 6119 S SD . MET D 2 141 ? -33.261 68.866 25.468 1.00 35.94 ? 137 MET J SD 1 ATOM 6120 C CE . MET D 2 141 ? -32.664 68.216 27.004 1.00 28.09 ? 137 MET J CE 1 ATOM 6121 N N . VAL D 2 142 ? -27.588 68.546 25.835 1.00 28.46 ? 138 VAL J N 1 ATOM 6122 C CA . VAL D 2 142 ? -26.298 68.016 25.379 1.00 27.05 ? 138 VAL J CA 1 ATOM 6123 C C . VAL D 2 142 ? -26.341 66.491 25.371 1.00 18.61 ? 138 VAL J C 1 ATOM 6124 O O . VAL D 2 142 ? -26.999 65.862 26.204 1.00 15.00 ? 138 VAL J O 1 ATOM 6125 C CB . VAL D 2 142 ? -25.089 68.402 26.247 1.00 27.31 ? 138 VAL J CB 1 ATOM 6126 C CG1 . VAL D 2 142 ? -24.886 69.897 26.082 1.00 37.64 ? 138 VAL J CG1 1 ATOM 6127 C CG2 . VAL D 2 142 ? -25.277 67.967 27.685 1.00 25.60 ? 138 VAL J CG2 1 ATOM 6128 N N . THR D 2 143 ? -25.617 65.963 24.399 1.00 12.85 ? 139 THR J N 1 ATOM 6129 C CA . THR D 2 143 ? -25.496 64.552 24.148 1.00 11.51 ? 139 THR J CA 1 ATOM 6130 C C . THR D 2 143 ? -24.134 64.062 24.599 1.00 13.85 ? 139 THR J C 1 ATOM 6131 O O . THR D 2 143 ? -23.086 64.665 24.317 1.00 17.82 ? 139 THR J O 1 ATOM 6132 C CB . THR D 2 143 ? -25.721 64.365 22.655 1.00 10.97 ? 139 THR J CB 1 ATOM 6133 O OG1 . THR D 2 143 ? -27.113 64.660 22.424 1.00 12.90 ? 139 THR J OG1 1 ATOM 6134 C CG2 . THR D 2 143 ? -25.298 63.012 22.160 1.00 4.89 ? 139 THR J CG2 1 ATOM 6135 N N . LEU D 2 144 ? -24.221 62.990 25.368 1.00 13.09 ? 140 LEU J N 1 ATOM 6136 C CA . LEU D 2 144 ? -23.065 62.284 25.880 1.00 13.43 ? 140 LEU J CA 1 ATOM 6137 C C . LEU D 2 144 ? -23.204 60.894 25.315 1.00 11.35 ? 140 LEU J C 1 ATOM 6138 O O . LEU D 2 144 ? -24.207 60.594 24.678 1.00 11.16 ? 140 LEU J O 1 ATOM 6139 C CB . LEU D 2 144 ? -23.078 62.114 27.375 1.00 8.18 ? 140 LEU J CB 1 ATOM 6140 C CG . LEU D 2 144 ? -23.470 63.291 28.210 1.00 12.02 ? 140 LEU J CG 1 ATOM 6141 C CD1 . LEU D 2 144 ? -23.349 62.913 29.649 1.00 6.01 ? 140 LEU J CD1 1 ATOM 6142 C CD2 . LEU D 2 144 ? -22.568 64.464 27.914 1.00 15.97 ? 140 LEU J CD2 1 ATOM 6143 N N . GLY D 2 145 ? -22.256 60.006 25.588 1.00 18.56 ? 141 GLY J N 1 ATOM 6144 C CA . GLY D 2 145 ? -22.352 58.592 25.235 1.00 17.71 ? 141 GLY J CA 1 ATOM 6145 C C . GLY D 2 145 ? -21.206 57.770 25.811 1.00 11.35 ? 141 GLY J C 1 ATOM 6146 O O . GLY D 2 145 ? -20.352 58.310 26.536 1.00 6.40 ? 141 GLY J O 1 ATOM 6147 N N . CYS D 2 146 ? -21.165 56.464 25.590 1.00 5.59 ? 142 CYS J N 1 ATOM 6148 C CA . CYS D 2 146 ? -19.932 55.778 25.905 1.00 10.30 ? 142 CYS J CA 1 ATOM 6149 C C . CYS D 2 146 ? -19.782 54.586 24.987 1.00 2.00 ? 142 CYS J C 1 ATOM 6150 O O . CYS D 2 146 ? -20.798 54.108 24.526 1.00 3.25 ? 142 CYS J O 1 ATOM 6151 C CB . CYS D 2 146 ? -19.932 55.426 27.389 1.00 8.30 ? 142 CYS J CB 1 ATOM 6152 S SG . CYS D 2 146 ? -20.902 54.013 27.867 1.00 17.41 ? 142 CYS J SG 1 ATOM 6153 N N . LEU D 2 147 ? -18.561 54.254 24.568 1.00 2.00 ? 143 LEU J N 1 ATOM 6154 C CA . LEU D 2 147 ? -18.198 53.234 23.561 1.00 10.92 ? 143 LEU J CA 1 ATOM 6155 C C . LEU D 2 147 ? -17.787 51.910 24.252 1.00 11.57 ? 143 LEU J C 1 ATOM 6156 O O . LEU D 2 147 ? -17.035 51.929 25.239 1.00 11.20 ? 143 LEU J O 1 ATOM 6157 C CB . LEU D 2 147 ? -17.009 53.789 22.680 1.00 8.17 ? 143 LEU J CB 1 ATOM 6158 C CG . LEU D 2 147 ? -16.467 53.008 21.489 1.00 2.00 ? 143 LEU J CG 1 ATOM 6159 C CD1 . LEU D 2 147 ? -17.460 53.159 20.382 1.00 8.23 ? 143 LEU J CD1 1 ATOM 6160 C CD2 . LEU D 2 147 ? -15.171 53.527 20.978 1.00 2.00 ? 143 LEU J CD2 1 ATOM 6161 N N . VAL D 2 148 ? -18.226 50.766 23.734 1.00 2.00 ? 144 VAL J N 1 ATOM 6162 C CA . VAL D 2 148 ? -18.024 49.486 24.354 1.00 2.00 ? 144 VAL J CA 1 ATOM 6163 C C . VAL D 2 148 ? -17.367 48.775 23.186 1.00 2.20 ? 144 VAL J C 1 ATOM 6164 O O . VAL D 2 148 ? -18.003 48.343 22.217 1.00 2.02 ? 144 VAL J O 1 ATOM 6165 C CB . VAL D 2 148 ? -19.421 48.937 24.732 1.00 6.45 ? 144 VAL J CB 1 ATOM 6166 C CG1 . VAL D 2 148 ? -19.237 47.579 25.343 1.00 8.30 ? 144 VAL J CG1 1 ATOM 6167 C CG2 . VAL D 2 148 ? -20.151 49.824 25.750 1.00 2.00 ? 144 VAL J CG2 1 ATOM 6168 N N . LYS D 2 149 ? -16.041 48.691 23.255 1.00 5.92 ? 145 LYS J N 1 ATOM 6169 C CA . LYS D 2 149 ? -15.195 48.195 22.183 1.00 5.54 ? 145 LYS J CA 1 ATOM 6170 C C . LYS D 2 149 ? -14.329 47.023 22.609 1.00 5.22 ? 145 LYS J C 1 ATOM 6171 O O . LYS D 2 149 ? -13.701 47.033 23.665 1.00 2.66 ? 145 LYS J O 1 ATOM 6172 C CB . LYS D 2 149 ? -14.352 49.401 21.704 1.00 9.05 ? 145 LYS J CB 1 ATOM 6173 C CG . LYS D 2 149 ? -13.065 49.248 20.878 1.00 11.72 ? 145 LYS J CG 1 ATOM 6174 C CD . LYS D 2 149 ? -13.048 50.070 19.591 1.00 14.02 ? 145 LYS J CD 1 ATOM 6175 C CE . LYS D 2 149 ? -11.629 50.301 19.116 1.00 23.00 ? 145 LYS J CE 1 ATOM 6176 N NZ . LYS D 2 149 ? -10.889 49.055 18.937 1.00 30.97 ? 145 LYS J NZ 1 ATOM 6177 N N . GLY D 2 150 ? -14.355 46.018 21.743 1.00 2.00 ? 146 GLY J N 1 ATOM 6178 C CA . GLY D 2 150 ? -13.553 44.820 21.857 1.00 3.58 ? 146 GLY J CA 1 ATOM 6179 C C . GLY D 2 150 ? -14.118 43.760 22.774 1.00 8.24 ? 146 GLY J C 1 ATOM 6180 O O . GLY D 2 150 ? -13.522 43.476 23.797 1.00 11.08 ? 146 GLY J O 1 ATOM 6181 N N . TYR D 2 151 ? -15.239 43.119 22.444 1.00 15.63 ? 147 TYR J N 1 ATOM 6182 C CA . TYR D 2 151 ? -15.819 42.107 23.323 1.00 15.43 ? 147 TYR J CA 1 ATOM 6183 C C . TYR D 2 151 ? -16.381 40.957 22.530 1.00 14.92 ? 147 TYR J C 1 ATOM 6184 O O . TYR D 2 151 ? -16.741 41.144 21.363 1.00 22.28 ? 147 TYR J O 1 ATOM 6185 C CB . TYR D 2 151 ? -16.934 42.684 24.187 1.00 12.62 ? 147 TYR J CB 1 ATOM 6186 C CG . TYR D 2 151 ? -18.193 43.211 23.512 1.00 15.62 ? 147 TYR J CG 1 ATOM 6187 C CD1 . TYR D 2 151 ? -18.287 44.542 23.123 1.00 16.41 ? 147 TYR J CD1 1 ATOM 6188 C CD2 . TYR D 2 151 ? -19.276 42.372 23.342 1.00 19.75 ? 147 TYR J CD2 1 ATOM 6189 C CE1 . TYR D 2 151 ? -19.442 45.053 22.570 1.00 8.26 ? 147 TYR J CE1 1 ATOM 6190 C CE2 . TYR D 2 151 ? -20.437 42.875 22.792 1.00 17.35 ? 147 TYR J CE2 1 ATOM 6191 C CZ . TYR D 2 151 ? -20.493 44.196 22.416 1.00 10.41 ? 147 TYR J CZ 1 ATOM 6192 O OH . TYR D 2 151 ? -21.634 44.648 21.842 1.00 13.82 ? 147 TYR J OH 1 ATOM 6193 N N . PHE D 2 152 ? -16.427 39.782 23.158 1.00 13.71 ? 148 PHE J N 1 ATOM 6194 C CA . PHE D 2 152 ? -16.900 38.554 22.545 1.00 7.05 ? 148 PHE J CA 1 ATOM 6195 C C . PHE D 2 152 ? -17.464 37.647 23.624 1.00 7.30 ? 148 PHE J C 1 ATOM 6196 O O . PHE D 2 152 ? -16.910 37.574 24.716 1.00 8.84 ? 148 PHE J O 1 ATOM 6197 C CB . PHE D 2 152 ? -15.768 37.848 21.878 1.00 6.64 ? 148 PHE J CB 1 ATOM 6198 C CG . PHE D 2 152 ? -16.339 36.939 20.822 1.00 12.81 ? 148 PHE J CG 1 ATOM 6199 C CD1 . PHE D 2 152 ? -16.656 37.476 19.587 1.00 13.10 ? 148 PHE J CD1 1 ATOM 6200 C CD2 . PHE D 2 152 ? -16.564 35.600 21.088 1.00 12.68 ? 148 PHE J CD2 1 ATOM 6201 C CE1 . PHE D 2 152 ? -17.202 36.667 18.606 1.00 7.41 ? 148 PHE J CE1 1 ATOM 6202 C CE2 . PHE D 2 152 ? -17.111 34.815 20.099 1.00 11.33 ? 148 PHE J CE2 1 ATOM 6203 C CZ . PHE D 2 152 ? -17.428 35.341 18.862 1.00 6.47 ? 148 PHE J CZ 1 ATOM 6204 N N . PRO D 2 153 ? -18.576 36.954 23.487 1.00 10.28 ? 149 PRO J N 1 ATOM 6205 C CA . PRO D 2 153 ? -19.571 37.176 22.445 1.00 11.39 ? 149 PRO J CA 1 ATOM 6206 C C . PRO D 2 153 ? -20.623 38.193 22.843 1.00 12.34 ? 149 PRO J C 1 ATOM 6207 O O . PRO D 2 153 ? -20.440 38.956 23.804 1.00 10.70 ? 149 PRO J O 1 ATOM 6208 C CB . PRO D 2 153 ? -20.094 35.781 22.214 1.00 9.47 ? 149 PRO J CB 1 ATOM 6209 C CG . PRO D 2 153 ? -20.123 35.253 23.617 1.00 3.40 ? 149 PRO J CG 1 ATOM 6210 C CD . PRO D 2 153 ? -18.803 35.698 24.188 1.00 5.22 ? 149 PRO J CD 1 ATOM 6211 N N . GLU D 2 154 ? -21.693 38.253 22.054 1.00 15.83 ? 150 GLU J N 1 ATOM 6212 C CA . GLU D 2 154 ? -22.838 39.095 22.390 1.00 22.07 ? 150 GLU J CA 1 ATOM 6213 C C . GLU D 2 154 ? -23.488 38.465 23.607 1.00 22.08 ? 150 GLU J C 1 ATOM 6214 O O . GLU D 2 154 ? -23.240 37.278 23.808 1.00 28.19 ? 150 GLU J O 1 ATOM 6215 C CB . GLU D 2 154 ? -23.841 39.115 21.242 1.00 30.44 ? 150 GLU J CB 1 ATOM 6216 C CG . GLU D 2 154 ? -23.708 40.227 20.164 1.00 38.82 ? 150 GLU J CG 1 ATOM 6217 C CD . GLU D 2 154 ? -24.054 41.653 20.609 1.00 40.11 ? 150 GLU J CD 1 ATOM 6218 O OE1 . GLU D 2 154 ? -23.308 42.232 21.387 1.00 42.63 ? 150 GLU J OE1 1 ATOM 6219 O OE2 . GLU D 2 154 ? -25.063 42.203 20.169 1.00 41.80 ? 150 GLU J OE2 1 ATOM 6220 N N . PRO D 2 155 ? -24.312 39.078 24.439 1.00 18.19 ? 151 PRO J N 1 ATOM 6221 C CA . PRO D 2 155 ? -24.643 40.487 24.435 1.00 18.33 ? 151 PRO J CA 1 ATOM 6222 C C . PRO D 2 155 ? -23.978 41.286 25.546 1.00 13.55 ? 151 PRO J C 1 ATOM 6223 O O . PRO D 2 155 ? -23.318 40.718 26.408 1.00 22.13 ? 151 PRO J O 1 ATOM 6224 C CB . PRO D 2 155 ? -26.141 40.436 24.524 1.00 21.74 ? 151 PRO J CB 1 ATOM 6225 C CG . PRO D 2 155 ? -26.339 39.418 25.620 1.00 16.95 ? 151 PRO J CG 1 ATOM 6226 C CD . PRO D 2 155 ? -25.329 38.351 25.191 1.00 15.54 ? 151 PRO J CD 1 ATOM 6227 N N . VAL D 2 156 ? -24.233 42.579 25.617 1.00 8.17 ? 152 VAL J N 1 ATOM 6228 C CA . VAL D 2 156 ? -23.660 43.423 26.642 1.00 5.50 ? 152 VAL J CA 1 ATOM 6229 C C . VAL D 2 156 ? -24.854 44.275 27.113 1.00 4.07 ? 152 VAL J C 1 ATOM 6230 O O . VAL D 2 156 ? -25.872 44.356 26.412 1.00 2.00 ? 152 VAL J O 1 ATOM 6231 C CB . VAL D 2 156 ? -22.483 44.163 25.912 1.00 5.71 ? 152 VAL J CB 1 ATOM 6232 C CG1 . VAL D 2 156 ? -22.992 45.355 25.116 1.00 11.88 ? 152 VAL J CG1 1 ATOM 6233 C CG2 . VAL D 2 156 ? -21.478 44.635 26.897 1.00 2.00 ? 152 VAL J CG2 1 ATOM 6234 N N . THR D 2 157 ? -24.871 44.874 28.290 1.00 10.43 ? 153 THR J N 1 ATOM 6235 C CA . THR D 2 157 ? -25.992 45.701 28.688 1.00 18.27 ? 153 THR J CA 1 ATOM 6236 C C . THR D 2 157 ? -25.475 47.051 29.102 1.00 21.70 ? 153 THR J C 1 ATOM 6237 O O . THR D 2 157 ? -24.494 47.170 29.844 1.00 22.70 ? 153 THR J O 1 ATOM 6238 C CB . THR D 2 157 ? -26.749 45.116 29.857 1.00 18.29 ? 153 THR J CB 1 ATOM 6239 O OG1 . THR D 2 157 ? -25.791 44.930 30.892 1.00 26.89 ? 153 THR J OG1 1 ATOM 6240 C CG2 . THR D 2 157 ? -27.472 43.824 29.484 1.00 16.68 ? 153 THR J CG2 1 ATOM 6241 N N . VAL D 2 158 ? -26.135 48.041 28.511 1.00 21.21 ? 154 VAL J N 1 ATOM 6242 C CA . VAL D 2 158 ? -25.802 49.419 28.742 1.00 17.13 ? 154 VAL J CA 1 ATOM 6243 C C . VAL D 2 158 ? -27.097 49.988 29.238 1.00 15.49 ? 154 VAL J C 1 ATOM 6244 O O . VAL D 2 158 ? -28.159 49.750 28.665 1.00 20.47 ? 154 VAL J O 1 ATOM 6245 C CB . VAL D 2 158 ? -25.379 50.108 27.451 1.00 14.96 ? 154 VAL J CB 1 ATOM 6246 C CG1 . VAL D 2 158 ? -24.978 51.541 27.759 1.00 16.79 ? 154 VAL J CG1 1 ATOM 6247 C CG2 . VAL D 2 158 ? -24.195 49.388 26.841 1.00 9.46 ? 154 VAL J CG2 1 ATOM 6248 N N . THR D 2 159 ? -26.991 50.564 30.411 1.00 15.83 ? 156 THR J N 1 ATOM 6249 C CA . THR D 2 159 ? -28.070 51.283 31.046 1.00 17.48 ? 156 THR J CA 1 ATOM 6250 C C . THR D 2 159 ? -27.357 52.572 31.449 1.00 21.53 ? 156 THR J C 1 ATOM 6251 O O . THR D 2 159 ? -26.110 52.637 31.379 1.00 23.11 ? 156 THR J O 1 ATOM 6252 C CB . THR D 2 159 ? -28.619 50.533 32.299 1.00 14.47 ? 156 THR J CB 1 ATOM 6253 O OG1 . THR D 2 159 ? -27.547 50.418 33.228 1.00 18.78 ? 156 THR J OG1 1 ATOM 6254 C CG2 . THR D 2 159 ? -29.197 49.155 31.972 1.00 13.92 ? 156 THR J CG2 1 ATOM 6255 N N . TRP D 2 160 ? -28.057 53.616 31.899 1.00 21.66 ? 157 TRP J N 1 ATOM 6256 C CA . TRP D 2 160 ? -27.377 54.868 32.218 1.00 20.65 ? 157 TRP J CA 1 ATOM 6257 C C . TRP D 2 160 ? -27.870 55.245 33.571 1.00 16.81 ? 157 TRP J C 1 ATOM 6258 O O . TRP D 2 160 ? -29.059 55.057 33.844 1.00 16.83 ? 157 TRP J O 1 ATOM 6259 C CB . TRP D 2 160 ? -27.740 56.004 31.238 1.00 19.44 ? 157 TRP J CB 1 ATOM 6260 C CG . TRP D 2 160 ? -27.123 55.839 29.862 1.00 12.37 ? 157 TRP J CG 1 ATOM 6261 C CD1 . TRP D 2 160 ? -27.698 55.063 28.890 1.00 6.29 ? 157 TRP J CD1 1 ATOM 6262 C CD2 . TRP D 2 160 ? -25.969 56.436 29.470 1.00 11.36 ? 157 TRP J CD2 1 ATOM 6263 N NE1 . TRP D 2 160 ? -26.901 55.178 27.870 1.00 6.57 ? 157 TRP J NE1 1 ATOM 6264 C CE2 . TRP D 2 160 ? -25.861 55.988 28.163 1.00 10.69 ? 157 TRP J CE2 1 ATOM 6265 C CE3 . TRP D 2 160 ? -25.041 57.276 30.044 1.00 11.98 ? 157 TRP J CE3 1 ATOM 6266 C CZ2 . TRP D 2 160 ? -24.785 56.395 27.393 1.00 12.35 ? 157 TRP J CZ2 1 ATOM 6267 C CZ3 . TRP D 2 160 ? -23.971 57.673 29.269 1.00 12.69 ? 157 TRP J CZ3 1 ATOM 6268 C CH2 . TRP D 2 160 ? -23.848 57.237 27.963 1.00 10.76 ? 157 TRP J CH2 1 ATOM 6269 N N . ASN D 2 161 ? -26.978 55.743 34.404 1.00 9.67 ? 162 ASN J N 1 ATOM 6270 C CA . ASN D 2 161 ? -27.301 56.070 35.768 1.00 18.92 ? 162 ASN J CA 1 ATOM 6271 C C . ASN D 2 161 ? -28.139 54.992 36.478 1.00 23.03 ? 162 ASN J C 1 ATOM 6272 O O . ASN D 2 161 ? -29.248 55.120 37.012 1.00 19.99 ? 162 ASN J O 1 ATOM 6273 C CB . ASN D 2 161 ? -27.968 57.441 35.708 1.00 20.40 ? 162 ASN J CB 1 ATOM 6274 C CG . ASN D 2 161 ? -26.913 58.493 36.004 1.00 23.80 ? 162 ASN J CG 1 ATOM 6275 O OD1 . ASN D 2 161 ? -25.789 58.389 35.511 1.00 27.88 ? 162 ASN J OD1 1 ATOM 6276 N ND2 . ASN D 2 161 ? -27.164 59.534 36.783 1.00 22.31 ? 162 ASN J ND2 1 ATOM 6277 N N . SER D 2 162 ? -27.582 53.801 36.374 1.00 26.25 ? 163 SER J N 1 ATOM 6278 C CA . SER D 2 162 ? -28.220 52.619 36.929 1.00 34.83 ? 163 SER J CA 1 ATOM 6279 C C . SER D 2 162 ? -29.650 52.400 36.429 1.00 35.34 ? 163 SER J C 1 ATOM 6280 O O . SER D 2 162 ? -30.427 51.687 37.052 1.00 43.79 ? 163 SER J O 1 ATOM 6281 C CB . SER D 2 162 ? -28.179 52.736 38.474 1.00 34.65 ? 163 SER J CB 1 ATOM 6282 O OG . SER D 2 162 ? -26.902 53.161 38.951 1.00 37.87 ? 163 SER J OG 1 ATOM 6283 N N . GLY D 2 163 ? -30.049 52.952 35.292 1.00 31.55 ? 164 GLY J N 1 ATOM 6284 C CA . GLY D 2 163 ? -31.408 52.767 34.804 1.00 35.44 ? 164 GLY J CA 1 ATOM 6285 C C . GLY D 2 163 ? -32.285 53.963 35.165 1.00 39.38 ? 164 GLY J C 1 ATOM 6286 O O . GLY D 2 163 ? -33.336 54.211 34.570 1.00 44.25 ? 164 GLY J O 1 ATOM 6287 N N . SER D 2 164 ? -31.870 54.809 36.085 1.00 37.93 ? 165 SER J N 1 ATOM 6288 C CA . SER D 2 164 ? -32.655 55.972 36.444 1.00 39.47 ? 165 SER J CA 1 ATOM 6289 C C . SER D 2 164 ? -32.460 57.123 35.435 1.00 40.55 ? 165 SER J C 1 ATOM 6290 O O . SER D 2 164 ? -32.606 58.302 35.771 1.00 46.65 ? 165 SER J O 1 ATOM 6291 C CB . SER D 2 164 ? -32.221 56.324 37.862 1.00 41.92 ? 165 SER J CB 1 ATOM 6292 O OG . SER D 2 164 ? -32.204 55.125 38.662 1.00 50.71 ? 165 SER J OG 1 ATOM 6293 N N . LEU D 2 165 ? -32.096 56.828 34.179 1.00 35.41 ? 166 LEU J N 1 ATOM 6294 C CA . LEU D 2 165 ? -31.868 57.796 33.114 1.00 27.35 ? 166 LEU J CA 1 ATOM 6295 C C . LEU D 2 165 ? -31.969 56.893 31.867 1.00 29.36 ? 166 LEU J C 1 ATOM 6296 O O . LEU D 2 165 ? -31.087 56.199 31.353 1.00 27.56 ? 166 LEU J O 1 ATOM 6297 C CB . LEU D 2 165 ? -30.487 58.436 33.298 1.00 12.06 ? 166 LEU J CB 1 ATOM 6298 C CG . LEU D 2 165 ? -30.291 59.745 32.586 1.00 6.78 ? 166 LEU J CG 1 ATOM 6299 C CD1 . LEU D 2 165 ? -28.830 60.217 32.695 1.00 2.00 ? 166 LEU J CD1 1 ATOM 6300 C CD2 . LEU D 2 165 ? -30.606 59.549 31.121 1.00 6.87 ? 166 LEU J CD2 1 ATOM 6301 N N . SER D 2 166 ? -33.221 56.932 31.482 1.00 32.06 ? 167 SER J N 1 ATOM 6302 C CA . SER D 2 166 ? -33.811 56.135 30.429 1.00 34.62 ? 167 SER J CA 1 ATOM 6303 C C . SER D 2 166 ? -34.512 57.015 29.405 1.00 34.97 ? 167 SER J C 1 ATOM 6304 O O . SER D 2 166 ? -35.223 56.529 28.531 1.00 27.94 ? 167 SER J O 1 ATOM 6305 C CB . SER D 2 166 ? -34.770 55.178 31.140 1.00 39.05 ? 167 SER J CB 1 ATOM 6306 O OG . SER D 2 166 ? -35.242 55.763 32.378 1.00 46.93 ? 167 SER J OG 1 ATOM 6307 N N . SER D 2 167 ? -34.200 58.314 29.531 1.00 39.02 ? 168 SER J N 1 ATOM 6308 C CA . SER D 2 167 ? -34.789 59.402 28.781 1.00 38.51 ? 168 SER J CA 1 ATOM 6309 C C . SER D 2 167 ? -34.670 59.157 27.297 1.00 40.10 ? 168 SER J C 1 ATOM 6310 O O . SER D 2 167 ? -35.529 58.490 26.731 1.00 47.48 ? 168 SER J O 1 ATOM 6311 C CB . SER D 2 167 ? -34.098 60.760 29.162 1.00 39.26 ? 168 SER J CB 1 ATOM 6312 O OG . SER D 2 167 ? -32.686 60.889 28.884 1.00 28.65 ? 168 SER J OG 1 ATOM 6313 N N . GLY D 2 168 ? -33.598 59.634 26.666 1.00 34.46 ? 169 GLY J N 1 ATOM 6314 C CA . GLY D 2 168 ? -33.460 59.518 25.241 1.00 30.56 ? 169 GLY J CA 1 ATOM 6315 C C . GLY D 2 168 ? -32.165 58.813 24.955 1.00 28.72 ? 169 GLY J C 1 ATOM 6316 O O . GLY D 2 168 ? -31.303 59.365 24.257 1.00 31.22 ? 169 GLY J O 1 ATOM 6317 N N . VAL D 2 169 ? -31.997 57.612 25.514 1.00 23.12 ? 171 VAL J N 1 ATOM 6318 C CA . VAL D 2 169 ? -30.752 56.933 25.244 1.00 18.65 ? 171 VAL J CA 1 ATOM 6319 C C . VAL D 2 169 ? -30.954 56.229 23.908 1.00 18.93 ? 171 VAL J C 1 ATOM 6320 O O . VAL D 2 169 ? -32.097 55.921 23.539 1.00 19.78 ? 171 VAL J O 1 ATOM 6321 C CB . VAL D 2 169 ? -30.383 55.930 26.372 1.00 10.24 ? 171 VAL J CB 1 ATOM 6322 C CG1 . VAL D 2 169 ? -30.645 56.647 27.660 1.00 13.38 ? 171 VAL J CG1 1 ATOM 6323 C CG2 . VAL D 2 169 ? -31.190 54.688 26.405 1.00 15.16 ? 171 VAL J CG2 1 ATOM 6324 N N . HIS D 2 170 ? -29.909 56.119 23.088 1.00 14.62 ? 172 HIS J N 1 ATOM 6325 C CA . HIS D 2 170 ? -29.992 55.343 21.876 1.00 10.56 ? 172 HIS J CA 1 ATOM 6326 C C . HIS D 2 170 ? -28.874 54.333 21.943 1.00 11.40 ? 172 HIS J C 1 ATOM 6327 O O . HIS D 2 170 ? -27.714 54.719 22.086 1.00 17.95 ? 172 HIS J O 1 ATOM 6328 C CB . HIS D 2 170 ? -29.764 56.175 20.682 1.00 11.51 ? 172 HIS J CB 1 ATOM 6329 C CG . HIS D 2 170 ? -30.929 57.022 20.259 1.00 12.34 ? 172 HIS J CG 1 ATOM 6330 N ND1 . HIS D 2 170 ? -30.849 58.018 19.396 1.00 14.50 ? 172 HIS J ND1 1 ATOM 6331 C CD2 . HIS D 2 170 ? -32.228 56.876 20.631 1.00 16.90 ? 172 HIS J CD2 1 ATOM 6332 C CE1 . HIS D 2 170 ? -32.044 58.480 19.224 1.00 17.68 ? 172 HIS J CE1 1 ATOM 6333 N NE2 . HIS D 2 170 ? -32.865 57.795 19.964 1.00 22.86 ? 172 HIS J NE2 1 ATOM 6334 N N . THR D 2 171 ? -29.123 53.050 21.880 1.00 9.65 ? 173 THR J N 1 ATOM 6335 C CA . THR D 2 171 ? -28.044 52.095 21.850 1.00 9.78 ? 173 THR J CA 1 ATOM 6336 C C . THR D 2 171 ? -28.096 51.447 20.464 1.00 13.97 ? 173 THR J C 1 ATOM 6337 O O . THR D 2 171 ? -29.140 50.983 19.991 1.00 20.69 ? 173 THR J O 1 ATOM 6338 C CB . THR D 2 171 ? -28.321 51.163 22.976 1.00 10.30 ? 173 THR J CB 1 ATOM 6339 O OG1 . THR D 2 171 ? -28.297 51.982 24.142 1.00 10.03 ? 173 THR J OG1 1 ATOM 6340 C CG2 . THR D 2 171 ? -27.376 49.990 22.995 1.00 16.38 ? 173 THR J CG2 1 ATOM 6341 N N . PHE D 2 172 ? -26.971 51.530 19.779 1.00 9.65 ? 174 PHE J N 1 ATOM 6342 C CA . PHE D 2 172 ? -26.811 51.036 18.436 1.00 6.89 ? 174 PHE J CA 1 ATOM 6343 C C . PHE D 2 172 ? -26.442 49.549 18.438 1.00 13.96 ? 174 PHE J C 1 ATOM 6344 O O . PHE D 2 172 ? -25.913 48.987 19.404 1.00 9.70 ? 174 PHE J O 1 ATOM 6345 C CB . PHE D 2 172 ? -25.739 51.862 17.780 1.00 6.52 ? 174 PHE J CB 1 ATOM 6346 C CG . PHE D 2 172 ? -26.185 53.320 17.762 1.00 12.13 ? 174 PHE J CG 1 ATOM 6347 C CD1 . PHE D 2 172 ? -25.923 54.141 18.861 1.00 10.44 ? 174 PHE J CD1 1 ATOM 6348 C CD2 . PHE D 2 172 ? -26.891 53.805 16.671 1.00 10.10 ? 174 PHE J CD2 1 ATOM 6349 C CE1 . PHE D 2 172 ? -26.373 55.438 18.876 1.00 7.24 ? 174 PHE J CE1 1 ATOM 6350 C CE2 . PHE D 2 172 ? -27.334 55.102 16.696 1.00 13.31 ? 174 PHE J CE2 1 ATOM 6351 C CZ . PHE D 2 172 ? -27.079 55.911 17.791 1.00 14.45 ? 174 PHE J CZ 1 ATOM 6352 N N . PRO D 2 173 ? -26.830 48.822 17.410 1.00 13.47 ? 175 PRO J N 1 ATOM 6353 C CA . PRO D 2 173 ? -26.307 47.500 17.118 1.00 12.25 ? 175 PRO J CA 1 ATOM 6354 C C . PRO D 2 173 ? -24.810 47.274 17.095 1.00 17.61 ? 175 PRO J C 1 ATOM 6355 O O . PRO D 2 173 ? -24.065 48.056 16.514 1.00 25.64 ? 175 PRO J O 1 ATOM 6356 C CB . PRO D 2 173 ? -26.961 47.202 15.837 1.00 7.19 ? 175 PRO J CB 1 ATOM 6357 C CG . PRO D 2 173 ? -28.353 47.614 16.240 1.00 7.63 ? 175 PRO J CG 1 ATOM 6358 C CD . PRO D 2 173 ? -28.145 48.984 16.820 1.00 7.05 ? 175 PRO J CD 1 ATOM 6359 N N . ALA D 2 174 ? -24.385 46.208 17.773 1.00 17.79 ? 176 ALA J N 1 ATOM 6360 C CA . ALA D 2 174 ? -22.996 45.796 17.796 1.00 16.41 ? 176 ALA J CA 1 ATOM 6361 C C . ALA D 2 174 ? -22.613 45.335 16.409 1.00 18.86 ? 176 ALA J C 1 ATOM 6362 O O . ALA D 2 174 ? -23.453 44.714 15.750 1.00 29.30 ? 176 ALA J O 1 ATOM 6363 C CB . ALA D 2 174 ? -22.753 44.606 18.720 1.00 9.49 ? 176 ALA J CB 1 ATOM 6364 N N . VAL D 2 175 ? -21.405 45.597 15.927 1.00 15.13 ? 177 VAL J N 1 ATOM 6365 C CA . VAL D 2 175 ? -20.986 45.060 14.657 1.00 12.23 ? 177 VAL J CA 1 ATOM 6366 C C . VAL D 2 175 ? -19.613 44.436 14.863 1.00 14.48 ? 177 VAL J C 1 ATOM 6367 O O . VAL D 2 175 ? -18.897 44.871 15.768 1.00 19.10 ? 177 VAL J O 1 ATOM 6368 C CB . VAL D 2 175 ? -21.024 46.229 13.620 1.00 11.23 ? 177 VAL J CB 1 ATOM 6369 C CG1 . VAL D 2 175 ? -20.038 47.277 13.961 1.00 8.08 ? 177 VAL J CG1 1 ATOM 6370 C CG2 . VAL D 2 175 ? -20.722 45.693 12.223 1.00 19.61 ? 177 VAL J CG2 1 ATOM 6371 N N . LEU D 2 176 ? -19.281 43.362 14.121 1.00 12.51 ? 178 LEU J N 1 ATOM 6372 C CA . LEU D 2 176 ? -17.995 42.684 14.184 1.00 14.07 ? 178 LEU J CA 1 ATOM 6373 C C . LEU D 2 176 ? -16.876 43.343 13.403 1.00 21.27 ? 178 LEU J C 1 ATOM 6374 O O . LEU D 2 176 ? -17.008 43.688 12.233 1.00 27.10 ? 178 LEU J O 1 ATOM 6375 C CB . LEU D 2 176 ? -18.085 41.317 13.646 1.00 15.09 ? 178 LEU J CB 1 ATOM 6376 C CG . LEU D 2 176 ? -18.821 40.295 14.444 1.00 18.27 ? 178 LEU J CG 1 ATOM 6377 C CD1 . LEU D 2 176 ? -19.818 39.636 13.516 1.00 19.50 ? 178 LEU J CD1 1 ATOM 6378 C CD2 . LEU D 2 176 ? -17.845 39.288 15.055 1.00 16.52 ? 178 LEU J CD2 1 ATOM 6379 N N . GLN D 2 177 ? -15.749 43.549 14.047 1.00 32.83 ? 179 GLN J N 1 ATOM 6380 C CA . GLN D 2 177 ? -14.587 44.141 13.405 1.00 43.81 ? 179 GLN J CA 1 ATOM 6381 C C . GLN D 2 177 ? -13.601 42.959 13.284 1.00 43.51 ? 179 GLN J C 1 ATOM 6382 O O . GLN D 2 177 ? -13.895 41.945 12.642 1.00 39.83 ? 179 GLN J O 1 ATOM 6383 C CB . GLN D 2 177 ? -14.026 45.270 14.311 1.00 51.24 ? 179 GLN J CB 1 ATOM 6384 C CG . GLN D 2 177 ? -14.947 46.215 15.102 1.00 57.60 ? 179 GLN J CG 1 ATOM 6385 C CD . GLN D 2 177 ? -14.175 47.199 15.991 1.00 62.49 ? 179 GLN J CD 1 ATOM 6386 O OE1 . GLN D 2 177 ? -13.737 48.275 15.576 1.00 62.59 ? 179 GLN J OE1 1 ATOM 6387 N NE2 . GLN D 2 177 ? -13.922 46.855 17.247 1.00 65.34 ? 179 GLN J NE2 1 ATOM 6388 N N . SER D 2 178 ? -12.446 42.984 13.972 1.00 39.76 ? 180 SER J N 1 ATOM 6389 C CA . SER D 2 178 ? -11.472 41.908 13.976 1.00 37.19 ? 180 SER J CA 1 ATOM 6390 C C . SER D 2 178 ? -11.988 40.803 14.908 1.00 38.63 ? 180 SER J C 1 ATOM 6391 O O . SER D 2 178 ? -11.620 40.687 16.082 1.00 38.48 ? 180 SER J O 1 ATOM 6392 C CB . SER D 2 178 ? -10.167 42.529 14.441 1.00 40.83 ? 180 SER J CB 1 ATOM 6393 O OG . SER D 2 178 ? -9.874 43.676 13.630 1.00 48.31 ? 180 SER J OG 1 ATOM 6394 N N . ASP D 2 179 ? -12.981 40.084 14.362 1.00 35.60 ? 183 ASP J N 1 ATOM 6395 C CA . ASP D 2 179 ? -13.745 39.026 15.010 1.00 32.51 ? 183 ASP J CA 1 ATOM 6396 C C . ASP D 2 179 ? -14.402 39.380 16.327 1.00 23.28 ? 183 ASP J C 1 ATOM 6397 O O . ASP D 2 179 ? -14.965 38.515 16.975 1.00 22.33 ? 183 ASP J O 1 ATOM 6398 C CB . ASP D 2 179 ? -12.874 37.777 15.238 1.00 41.19 ? 183 ASP J CB 1 ATOM 6399 C CG . ASP D 2 179 ? -13.415 36.553 14.485 1.00 46.81 ? 183 ASP J CG 1 ATOM 6400 O OD1 . ASP D 2 179 ? -14.610 36.242 14.630 1.00 45.80 ? 183 ASP J OD1 1 ATOM 6401 O OD2 . ASP D 2 179 ? -12.635 35.925 13.752 1.00 46.12 ? 183 ASP J OD2 1 ATOM 6402 N N . LEU D 2 180 ? -14.463 40.667 16.648 1.00 17.84 ? 184 LEU J N 1 ATOM 6403 C CA . LEU D 2 180 ? -14.950 41.184 17.904 1.00 17.68 ? 184 LEU J CA 1 ATOM 6404 C C . LEU D 2 180 ? -16.026 42.254 17.782 1.00 18.33 ? 184 LEU J C 1 ATOM 6405 O O . LEU D 2 180 ? -16.057 43.032 16.837 1.00 20.21 ? 184 LEU J O 1 ATOM 6406 C CB . LEU D 2 180 ? -13.751 41.709 18.631 1.00 16.29 ? 184 LEU J CB 1 ATOM 6407 C CG . LEU D 2 180 ? -13.096 40.884 19.737 1.00 19.00 ? 184 LEU J CG 1 ATOM 6408 C CD1 . LEU D 2 180 ? -13.399 39.390 19.627 1.00 17.37 ? 184 LEU J CD1 1 ATOM 6409 C CD2 . LEU D 2 180 ? -11.608 41.152 19.652 1.00 9.11 ? 184 LEU J CD2 1 ATOM 6410 N N . TYR D 2 181 ? -16.902 42.331 18.758 1.00 18.49 ? 185 TYR J N 1 ATOM 6411 C CA . TYR D 2 181 ? -18.007 43.250 18.747 1.00 19.78 ? 185 TYR J CA 1 ATOM 6412 C C . TYR D 2 181 ? -17.673 44.680 19.161 1.00 19.50 ? 185 TYR J C 1 ATOM 6413 O O . TYR D 2 181 ? -16.646 44.937 19.805 1.00 18.51 ? 185 TYR J O 1 ATOM 6414 C CB . TYR D 2 181 ? -19.084 42.646 19.656 1.00 22.52 ? 185 TYR J CB 1 ATOM 6415 C CG . TYR D 2 181 ? -19.816 41.476 19.033 1.00 23.87 ? 185 TYR J CG 1 ATOM 6416 C CD1 . TYR D 2 181 ? -20.507 41.668 17.858 1.00 30.95 ? 185 TYR J CD1 1 ATOM 6417 C CD2 . TYR D 2 181 ? -19.755 40.222 19.581 1.00 23.10 ? 185 TYR J CD2 1 ATOM 6418 C CE1 . TYR D 2 181 ? -21.126 40.603 17.229 1.00 34.19 ? 185 TYR J CE1 1 ATOM 6419 C CE2 . TYR D 2 181 ? -20.376 39.154 18.952 1.00 29.83 ? 185 TYR J CE2 1 ATOM 6420 C CZ . TYR D 2 181 ? -21.062 39.340 17.768 1.00 31.54 ? 185 TYR J CZ 1 ATOM 6421 O OH . TYR D 2 181 ? -21.656 38.278 17.089 1.00 33.82 ? 185 TYR J OH 1 ATOM 6422 N N . THR D 2 182 ? -18.519 45.649 18.802 1.00 19.66 ? 186 THR J N 1 ATOM 6423 C CA . THR D 2 182 ? -18.404 47.047 19.193 1.00 16.37 ? 186 THR J CA 1 ATOM 6424 C C . THR D 2 182 ? -19.809 47.661 19.167 1.00 14.71 ? 186 THR J C 1 ATOM 6425 O O . THR D 2 182 ? -20.542 47.506 18.193 1.00 14.05 ? 186 THR J O 1 ATOM 6426 C CB . THR D 2 182 ? -17.498 47.771 18.223 1.00 14.87 ? 186 THR J CB 1 ATOM 6427 O OG1 . THR D 2 182 ? -16.353 46.945 18.040 1.00 16.48 ? 186 THR J OG1 1 ATOM 6428 C CG2 . THR D 2 182 ? -17.086 49.135 18.742 1.00 13.92 ? 186 THR J CG2 1 ATOM 6429 N N . LEU D 2 183 ? -20.167 48.424 20.196 1.00 14.38 ? 187 LEU J N 1 ATOM 6430 C CA . LEU D 2 183 ? -21.509 48.901 20.504 1.00 8.63 ? 187 LEU J CA 1 ATOM 6431 C C . LEU D 2 183 ? -21.255 50.232 21.217 1.00 16.95 ? 187 LEU J C 1 ATOM 6432 O O . LEU D 2 183 ? -20.280 50.352 21.978 1.00 18.47 ? 187 LEU J O 1 ATOM 6433 C CB . LEU D 2 183 ? -22.043 47.820 21.398 1.00 9.15 ? 187 LEU J CB 1 ATOM 6434 C CG . LEU D 2 183 ? -23.259 47.634 22.226 1.00 2.00 ? 187 LEU J CG 1 ATOM 6435 C CD1 . LEU D 2 183 ? -23.506 48.814 23.124 1.00 4.79 ? 187 LEU J CD1 1 ATOM 6436 C CD2 . LEU D 2 183 ? -24.363 47.338 21.275 1.00 8.19 ? 187 LEU J CD2 1 ATOM 6437 N N . SER D 2 184 ? -22.118 51.235 21.033 1.00 18.27 ? 188 SER J N 1 ATOM 6438 C CA . SER D 2 184 ? -21.978 52.567 21.609 1.00 11.32 ? 188 SER J CA 1 ATOM 6439 C C . SER D 2 184 ? -23.371 53.090 21.870 1.00 10.30 ? 188 SER J C 1 ATOM 6440 O O . SER D 2 184 ? -24.293 52.773 21.116 1.00 17.69 ? 188 SER J O 1 ATOM 6441 C CB . SER D 2 184 ? -21.245 53.443 20.619 1.00 18.00 ? 188 SER J CB 1 ATOM 6442 O OG . SER D 2 184 ? -21.582 53.129 19.266 1.00 24.92 ? 188 SER J OG 1 ATOM 6443 N N . SER D 2 185 ? -23.565 53.895 22.888 1.00 5.79 ? 189 SER J N 1 ATOM 6444 C CA . SER D 2 185 ? -24.863 54.327 23.314 1.00 3.11 ? 189 SER J CA 1 ATOM 6445 C C . SER D 2 185 ? -24.820 55.815 23.509 1.00 2.82 ? 189 SER J C 1 ATOM 6446 O O . SER D 2 185 ? -23.862 56.319 24.083 1.00 8.51 ? 189 SER J O 1 ATOM 6447 C CB . SER D 2 185 ? -25.172 53.616 24.623 1.00 3.25 ? 189 SER J CB 1 ATOM 6448 O OG . SER D 2 185 ? -26.371 54.055 25.260 1.00 6.60 ? 189 SER J OG 1 ATOM 6449 N N . SER D 2 186 ? -25.811 56.558 23.092 1.00 7.67 ? 190 SER J N 1 ATOM 6450 C CA . SER D 2 186 ? -25.836 57.975 23.401 1.00 14.77 ? 190 SER J CA 1 ATOM 6451 C C . SER D 2 186 ? -26.958 58.209 24.402 1.00 16.26 ? 190 SER J C 1 ATOM 6452 O O . SER D 2 186 ? -27.777 57.318 24.653 1.00 18.69 ? 190 SER J O 1 ATOM 6453 C CB . SER D 2 186 ? -26.077 58.812 22.149 1.00 16.88 ? 190 SER J CB 1 ATOM 6454 O OG . SER D 2 186 ? -27.142 58.351 21.326 1.00 28.56 ? 190 SER J OG 1 ATOM 6455 N N . VAL D 2 187 ? -26.930 59.367 25.016 1.00 10.71 ? 191 VAL J N 1 ATOM 6456 C CA . VAL D 2 187 ? -27.901 59.807 25.964 1.00 11.08 ? 191 VAL J CA 1 ATOM 6457 C C . VAL D 2 187 ? -27.880 61.326 25.760 1.00 15.69 ? 191 VAL J C 1 ATOM 6458 O O . VAL D 2 187 ? -26.880 61.916 25.343 1.00 19.62 ? 191 VAL J O 1 ATOM 6459 C CB . VAL D 2 187 ? -27.445 59.392 27.360 1.00 10.83 ? 191 VAL J CB 1 ATOM 6460 C CG1 . VAL D 2 187 ? -26.144 60.077 27.752 1.00 20.13 ? 191 VAL J CG1 1 ATOM 6461 C CG2 . VAL D 2 187 ? -28.452 59.864 28.377 1.00 13.19 ? 191 VAL J CG2 1 ATOM 6462 N N . THR D 2 188 ? -28.951 61.983 26.132 1.00 12.97 ? 192 THR J N 1 ATOM 6463 C CA . THR D 2 188 ? -29.128 63.390 25.933 1.00 11.04 ? 192 THR J CA 1 ATOM 6464 C C . THR D 2 188 ? -29.711 63.832 27.244 1.00 9.16 ? 192 THR J C 1 ATOM 6465 O O . THR D 2 188 ? -30.693 63.246 27.726 1.00 12.81 ? 192 THR J O 1 ATOM 6466 C CB . THR D 2 188 ? -30.070 63.520 24.759 1.00 10.59 ? 192 THR J CB 1 ATOM 6467 O OG1 . THR D 2 188 ? -29.268 63.144 23.641 1.00 16.73 ? 192 THR J OG1 1 ATOM 6468 C CG2 . THR D 2 188 ? -30.686 64.871 24.581 1.00 12.18 ? 192 THR J CG2 1 ATOM 6469 N N . VAL D 2 189 ? -29.036 64.792 27.844 1.00 5.10 ? 193 VAL J N 1 ATOM 6470 C CA . VAL D 2 189 ? -29.443 65.343 29.111 1.00 7.61 ? 193 VAL J CA 1 ATOM 6471 C C . VAL D 2 189 ? -29.582 66.832 28.871 1.00 8.42 ? 193 VAL J C 1 ATOM 6472 O O . VAL D 2 189 ? -28.859 67.413 28.054 1.00 12.48 ? 193 VAL J O 1 ATOM 6473 C CB . VAL D 2 189 ? -28.392 65.114 30.273 1.00 10.98 ? 193 VAL J CB 1 ATOM 6474 C CG1 . VAL D 2 189 ? -28.379 63.627 30.547 1.00 12.73 ? 193 VAL J CG1 1 ATOM 6475 C CG2 . VAL D 2 189 ? -26.972 65.618 29.954 1.00 8.98 ? 193 VAL J CG2 1 ATOM 6476 N N . PRO D 2 190 ? -30.488 67.518 29.548 1.00 3.19 ? 194 PRO J N 1 ATOM 6477 C CA . PRO D 2 190 ? -30.464 68.948 29.695 1.00 6.03 ? 194 PRO J CA 1 ATOM 6478 C C . PRO D 2 190 ? -29.106 69.422 30.147 1.00 8.10 ? 194 PRO J C 1 ATOM 6479 O O . PRO D 2 190 ? -28.532 68.934 31.116 1.00 4.52 ? 194 PRO J O 1 ATOM 6480 C CB . PRO D 2 190 ? -31.550 69.268 30.697 1.00 5.64 ? 194 PRO J CB 1 ATOM 6481 C CG . PRO D 2 190 ? -31.653 68.001 31.463 1.00 5.82 ? 194 PRO J CG 1 ATOM 6482 C CD . PRO D 2 190 ? -31.548 66.954 30.344 1.00 3.51 ? 194 PRO J CD 1 ATOM 6483 N N . SER D 2 191 ? -28.682 70.453 29.436 1.00 16.90 ? 195 SER J N 1 ATOM 6484 C CA . SER D 2 191 ? -27.397 71.106 29.585 1.00 20.88 ? 195 SER J CA 1 ATOM 6485 C C . SER D 2 191 ? -27.100 71.520 30.992 1.00 23.99 ? 195 SER J C 1 ATOM 6486 O O . SER D 2 191 ? -25.931 71.555 31.341 1.00 35.60 ? 195 SER J O 1 ATOM 6487 C CB . SER D 2 191 ? -27.360 72.318 28.666 1.00 26.16 ? 195 SER J CB 1 ATOM 6488 O OG . SER D 2 191 ? -27.596 71.932 27.293 1.00 31.53 ? 195 SER J OG 1 ATOM 6489 N N . SER D 2 192 ? -28.103 71.762 31.817 1.00 26.58 ? 196 SER J N 1 ATOM 6490 C CA . SER D 2 192 ? -27.918 72.163 33.189 1.00 28.02 ? 196 SER J CA 1 ATOM 6491 C C . SER D 2 192 ? -27.527 71.055 34.161 1.00 32.95 ? 196 SER J C 1 ATOM 6492 O O . SER D 2 192 ? -26.940 71.363 35.196 1.00 36.66 ? 196 SER J O 1 ATOM 6493 C CB . SER D 2 192 ? -29.203 72.833 33.606 1.00 33.76 ? 196 SER J CB 1 ATOM 6494 O OG . SER D 2 192 ? -30.346 72.345 32.877 1.00 39.60 ? 196 SER J OG 1 ATOM 6495 N N . PRO D 2 193 ? -27.887 69.774 33.978 1.00 34.43 ? 198 PRO J N 1 ATOM 6496 C CA . PRO D 2 193 ? -27.198 68.658 34.605 1.00 32.29 ? 198 PRO J CA 1 ATOM 6497 C C . PRO D 2 193 ? -25.857 68.248 34.083 1.00 29.42 ? 198 PRO J C 1 ATOM 6498 O O . PRO D 2 193 ? -25.085 67.834 34.940 1.00 26.94 ? 198 PRO J O 1 ATOM 6499 C CB . PRO D 2 193 ? -28.107 67.480 34.523 1.00 34.73 ? 198 PRO J CB 1 ATOM 6500 C CG . PRO D 2 193 ? -29.434 68.125 34.683 1.00 36.86 ? 198 PRO J CG 1 ATOM 6501 C CD . PRO D 2 193 ? -29.270 69.342 33.802 1.00 36.17 ? 198 PRO J CD 1 ATOM 6502 N N . ARG D 2 194 ? -25.588 68.436 32.770 1.00 32.39 ? 199 ARG J N 1 ATOM 6503 C CA . ARG D 2 194 ? -24.478 67.838 32.020 1.00 30.37 ? 199 ARG J CA 1 ATOM 6504 C C . ARG D 2 194 ? -23.353 67.666 32.937 1.00 30.39 ? 199 ARG J C 1 ATOM 6505 O O . ARG D 2 194 ? -23.084 66.494 33.159 1.00 34.50 ? 199 ARG J O 1 ATOM 6506 C CB . ARG D 2 194 ? -23.964 68.658 30.786 1.00 34.01 ? 199 ARG J CB 1 ATOM 6507 C CG . ARG D 2 194 ? -22.480 68.594 30.256 1.00 34.39 ? 199 ARG J CG 1 ATOM 6508 C CD . ARG D 2 194 ? -21.848 67.254 29.852 1.00 33.70 ? 199 ARG J CD 1 ATOM 6509 N NE . ARG D 2 194 ? -20.781 66.765 30.715 1.00 28.38 ? 199 ARG J NE 1 ATOM 6510 C CZ . ARG D 2 194 ? -20.907 65.687 31.512 1.00 29.28 ? 199 ARG J CZ 1 ATOM 6511 N NH1 . ARG D 2 194 ? -22.020 64.976 31.664 1.00 24.08 ? 199 ARG J NH1 1 ATOM 6512 N NH2 . ARG D 2 194 ? -19.889 65.303 32.256 1.00 35.26 ? 199 ARG J NH2 1 ATOM 6513 N N . PRO D 2 195 ? -22.777 68.668 33.598 1.00 26.34 ? 200 PRO J N 1 ATOM 6514 C CA . PRO D 2 195 ? -21.667 68.380 34.510 1.00 28.56 ? 200 PRO J CA 1 ATOM 6515 C C . PRO D 2 195 ? -22.007 68.293 36.001 1.00 30.59 ? 200 PRO J C 1 ATOM 6516 O O . PRO D 2 195 ? -21.397 67.533 36.755 1.00 35.24 ? 200 PRO J O 1 ATOM 6517 C CB . PRO D 2 195 ? -20.682 69.466 34.156 1.00 22.87 ? 200 PRO J CB 1 ATOM 6518 C CG . PRO D 2 195 ? -21.416 70.313 33.097 1.00 25.78 ? 200 PRO J CG 1 ATOM 6519 C CD . PRO D 2 195 ? -22.901 70.092 33.353 1.00 20.49 ? 200 PRO J CD 1 ATOM 6520 N N . SER D 2 196 ? -23.000 69.086 36.394 1.00 29.31 ? 202 SER J N 1 ATOM 6521 C CA . SER D 2 196 ? -23.401 69.334 37.757 1.00 33.94 ? 202 SER J CA 1 ATOM 6522 C C . SER D 2 196 ? -24.000 68.131 38.417 1.00 36.75 ? 202 SER J C 1 ATOM 6523 O O . SER D 2 196 ? -24.058 68.050 39.641 1.00 39.74 ? 202 SER J O 1 ATOM 6524 C CB . SER D 2 196 ? -24.409 70.459 37.762 1.00 38.62 ? 202 SER J CB 1 ATOM 6525 O OG . SER D 2 196 ? -24.104 71.345 36.680 1.00 46.81 ? 202 SER J OG 1 ATOM 6526 N N . GLU D 2 197 ? -24.526 67.240 37.607 1.00 38.57 ? 203 GLU J N 1 ATOM 6527 C CA . GLU D 2 197 ? -25.099 66.016 38.089 1.00 37.87 ? 203 GLU J CA 1 ATOM 6528 C C . GLU D 2 197 ? -24.268 65.043 37.280 1.00 33.42 ? 203 GLU J C 1 ATOM 6529 O O . GLU D 2 197 ? -23.887 65.322 36.147 1.00 28.33 ? 203 GLU J O 1 ATOM 6530 C CB . GLU D 2 197 ? -26.597 65.982 37.748 1.00 42.36 ? 203 GLU J CB 1 ATOM 6531 C CG . GLU D 2 197 ? -27.481 66.807 38.714 1.00 43.15 ? 203 GLU J CG 1 ATOM 6532 C CD . GLU D 2 197 ? -28.995 66.542 38.653 1.00 46.52 ? 203 GLU J CD 1 ATOM 6533 O OE1 . GLU D 2 197 ? -29.481 65.558 39.215 1.00 45.94 ? 203 GLU J OE1 1 ATOM 6534 O OE2 . GLU D 2 197 ? -29.712 67.339 38.057 1.00 50.65 ? 203 GLU J OE2 1 ATOM 6535 N N . THR D 2 198 ? -23.909 63.928 37.883 1.00 36.42 ? 204 THR J N 1 ATOM 6536 C CA . THR D 2 198 ? -23.025 62.953 37.263 1.00 38.90 ? 204 THR J CA 1 ATOM 6537 C C . THR D 2 198 ? -23.776 62.003 36.305 1.00 42.61 ? 204 THR J C 1 ATOM 6538 O O . THR D 2 198 ? -24.796 61.437 36.729 1.00 47.63 ? 204 THR J O 1 ATOM 6539 C CB . THR D 2 198 ? -22.321 62.201 38.449 1.00 33.58 ? 204 THR J CB 1 ATOM 6540 O OG1 . THR D 2 198 ? -23.361 61.869 39.363 1.00 30.66 ? 204 THR J OG1 1 ATOM 6541 C CG2 . THR D 2 198 ? -21.270 63.022 39.199 1.00 28.91 ? 204 THR J CG2 1 ATOM 6542 N N . VAL D 2 199 ? -23.378 61.803 35.029 1.00 42.55 ? 205 VAL J N 1 ATOM 6543 C CA . VAL D 2 199 ? -24.007 60.820 34.119 1.00 34.75 ? 205 VAL J CA 1 ATOM 6544 C C . VAL D 2 199 ? -22.973 59.735 33.996 1.00 28.28 ? 205 VAL J C 1 ATOM 6545 O O . VAL D 2 199 ? -21.801 60.023 33.733 1.00 23.83 ? 205 VAL J O 1 ATOM 6546 C CB . VAL D 2 199 ? -24.265 61.281 32.655 1.00 33.42 ? 205 VAL J CB 1 ATOM 6547 C CG1 . VAL D 2 199 ? -25.032 60.182 31.949 1.00 33.96 ? 205 VAL J CG1 1 ATOM 6548 C CG2 . VAL D 2 199 ? -25.087 62.566 32.587 1.00 36.21 ? 205 VAL J CG2 1 ATOM 6549 N N . THR D 2 200 ? -23.389 58.499 34.153 1.00 27.47 ? 206 THR J N 1 ATOM 6550 C CA . THR D 2 200 ? -22.477 57.395 34.098 1.00 24.89 ? 206 THR J CA 1 ATOM 6551 C C . THR D 2 200 ? -23.110 56.244 33.338 1.00 19.98 ? 206 THR J C 1 ATOM 6552 O O . THR D 2 200 ? -24.321 56.015 33.489 1.00 18.55 ? 206 THR J O 1 ATOM 6553 C CB . THR D 2 200 ? -22.148 57.124 35.564 1.00 25.96 ? 206 THR J CB 1 ATOM 6554 O OG1 . THR D 2 200 ? -21.019 56.305 35.454 1.00 30.83 ? 206 THR J OG1 1 ATOM 6555 C CG2 . THR D 2 200 ? -23.192 56.439 36.407 1.00 28.44 ? 206 THR J CG2 1 ATOM 6556 N N . CYS D 2 201 ? -22.394 55.608 32.406 1.00 17.84 ? 208 CYS J N 1 ATOM 6557 C CA . CYS D 2 201 ? -23.002 54.459 31.740 1.00 17.42 ? 208 CYS J CA 1 ATOM 6558 C C . CYS D 2 201 ? -22.384 53.250 32.379 1.00 13.99 ? 208 CYS J C 1 ATOM 6559 O O . CYS D 2 201 ? -21.240 53.234 32.835 1.00 19.22 ? 208 CYS J O 1 ATOM 6560 C CB . CYS D 2 201 ? -22.752 54.412 30.231 1.00 14.16 ? 208 CYS J CB 1 ATOM 6561 S SG . CYS D 2 201 ? -21.014 54.578 29.797 1.00 22.00 ? 208 CYS J SG 1 ATOM 6562 N N . ASN D 2 202 ? -23.183 52.226 32.432 1.00 13.90 ? 209 ASN J N 1 ATOM 6563 C CA . ASN D 2 202 ? -22.815 51.063 33.181 1.00 13.91 ? 209 ASN J CA 1 ATOM 6564 C C . ASN D 2 202 ? -22.829 49.962 32.148 1.00 17.85 ? 209 ASN J C 1 ATOM 6565 O O . ASN D 2 202 ? -23.847 49.814 31.461 1.00 25.59 ? 209 ASN J O 1 ATOM 6566 C CB . ASN D 2 202 ? -23.847 50.739 34.196 1.00 11.13 ? 209 ASN J CB 1 ATOM 6567 C CG . ASN D 2 202 ? -24.400 51.868 35.020 1.00 13.24 ? 209 ASN J CG 1 ATOM 6568 O OD1 . ASN D 2 202 ? -23.732 52.583 35.757 1.00 17.36 ? 209 ASN J OD1 1 ATOM 6569 N ND2 . ASN D 2 202 ? -25.703 52.060 34.923 1.00 12.08 ? 209 ASN J ND2 1 ATOM 6570 N N . VAL D 2 203 ? -21.761 49.205 31.979 1.00 12.32 ? 210 VAL J N 1 ATOM 6571 C CA . VAL D 2 203 ? -21.786 48.160 30.999 1.00 13.94 ? 210 VAL J CA 1 ATOM 6572 C C . VAL D 2 203 ? -21.738 46.850 31.759 1.00 14.89 ? 210 VAL J C 1 ATOM 6573 O O . VAL D 2 203 ? -21.069 46.781 32.799 1.00 15.49 ? 210 VAL J O 1 ATOM 6574 C CB . VAL D 2 203 ? -20.565 48.306 30.070 1.00 13.12 ? 210 VAL J CB 1 ATOM 6575 C CG1 . VAL D 2 203 ? -20.618 47.237 28.997 1.00 10.17 ? 210 VAL J CG1 1 ATOM 6576 C CG2 . VAL D 2 203 ? -20.562 49.661 29.397 1.00 14.96 ? 210 VAL J CG2 1 ATOM 6577 N N . ALA D 2 204 ? -22.410 45.812 31.269 1.00 14.63 ? 211 ALA J N 1 ATOM 6578 C CA . ALA D 2 204 ? -22.225 44.492 31.828 1.00 15.72 ? 211 ALA J CA 1 ATOM 6579 C C . ALA D 2 204 ? -21.994 43.528 30.692 1.00 19.19 ? 211 ALA J C 1 ATOM 6580 O O . ALA D 2 204 ? -22.797 43.506 29.763 1.00 22.56 ? 211 ALA J O 1 ATOM 6581 C CB . ALA D 2 204 ? -23.430 43.980 32.525 1.00 18.63 ? 211 ALA J CB 1 ATOM 6582 N N . HIS D 2 205 ? -20.919 42.748 30.656 1.00 20.22 ? 212 HIS J N 1 ATOM 6583 C CA . HIS D 2 205 ? -20.754 41.722 29.641 1.00 16.48 ? 212 HIS J CA 1 ATOM 6584 C C . HIS D 2 205 ? -21.042 40.489 30.472 1.00 23.41 ? 212 HIS J C 1 ATOM 6585 O O . HIS D 2 205 ? -20.176 40.187 31.288 1.00 25.00 ? 212 HIS J O 1 ATOM 6586 C CB . HIS D 2 205 ? -19.334 41.646 29.161 1.00 15.79 ? 212 HIS J CB 1 ATOM 6587 C CG . HIS D 2 205 ? -19.060 40.664 28.029 1.00 17.10 ? 212 HIS J CG 1 ATOM 6588 N ND1 . HIS D 2 205 ? -18.022 39.847 27.956 1.00 20.51 ? 212 HIS J ND1 1 ATOM 6589 C CD2 . HIS D 2 205 ? -19.816 40.469 26.888 1.00 16.47 ? 212 HIS J CD2 1 ATOM 6590 C CE1 . HIS D 2 205 ? -18.118 39.175 26.829 1.00 16.72 ? 212 HIS J CE1 1 ATOM 6591 N NE2 . HIS D 2 205 ? -19.198 39.552 26.193 1.00 14.58 ? 212 HIS J NE2 1 ATOM 6592 N N . PRO D 2 206 ? -22.151 39.742 30.413 1.00 25.63 ? 213 PRO J N 1 ATOM 6593 C CA . PRO D 2 206 ? -22.314 38.522 31.185 1.00 20.95 ? 213 PRO J CA 1 ATOM 6594 C C . PRO D 2 206 ? -21.295 37.430 30.844 1.00 19.79 ? 213 PRO J C 1 ATOM 6595 O O . PRO D 2 206 ? -20.575 36.992 31.745 1.00 18.65 ? 213 PRO J O 1 ATOM 6596 C CB . PRO D 2 206 ? -23.749 38.169 30.926 1.00 18.08 ? 213 PRO J CB 1 ATOM 6597 C CG . PRO D 2 206 ? -24.382 39.527 30.880 1.00 20.30 ? 213 PRO J CG 1 ATOM 6598 C CD . PRO D 2 206 ? -23.439 40.183 29.895 1.00 25.78 ? 213 PRO J CD 1 ATOM 6599 N N . ALA D 2 207 ? -21.122 37.019 29.583 1.00 15.68 ? 214 ALA J N 1 ATOM 6600 C CA . ALA D 2 207 ? -20.156 35.979 29.242 1.00 15.11 ? 214 ALA J CA 1 ATOM 6601 C C . ALA D 2 207 ? -18.823 35.965 29.980 1.00 19.37 ? 214 ALA J C 1 ATOM 6602 O O . ALA D 2 207 ? -18.273 34.879 30.100 1.00 30.27 ? 214 ALA J O 1 ATOM 6603 C CB . ALA D 2 207 ? -19.815 36.035 27.774 1.00 12.12 ? 214 ALA J CB 1 ATOM 6604 N N . SER D 2 208 ? -18.269 37.099 30.437 1.00 18.90 ? 215 SER J N 1 ATOM 6605 C CA . SER D 2 208 ? -17.055 37.149 31.253 1.00 25.79 ? 215 SER J CA 1 ATOM 6606 C C . SER D 2 208 ? -17.585 38.030 32.345 1.00 29.79 ? 215 SER J C 1 ATOM 6607 O O . SER D 2 208 ? -17.816 39.173 31.984 1.00 40.78 ? 215 SER J O 1 ATOM 6608 C CB . SER D 2 208 ? -15.903 37.872 30.568 1.00 24.77 ? 215 SER J CB 1 ATOM 6609 O OG . SER D 2 208 ? -16.138 39.153 29.943 1.00 25.56 ? 215 SER J OG 1 ATOM 6610 N N . SER D 2 209 ? -17.859 37.643 33.576 1.00 29.94 ? 216 SER J N 1 ATOM 6611 C CA . SER D 2 209 ? -18.528 38.516 34.516 1.00 33.36 ? 216 SER J CA 1 ATOM 6612 C C . SER D 2 209 ? -17.834 39.831 34.791 1.00 32.02 ? 216 SER J C 1 ATOM 6613 O O . SER D 2 209 ? -17.101 40.029 35.757 1.00 37.85 ? 216 SER J O 1 ATOM 6614 C CB . SER D 2 209 ? -18.729 37.729 35.801 1.00 43.32 ? 216 SER J CB 1 ATOM 6615 O OG . SER D 2 209 ? -19.331 36.465 35.510 1.00 49.36 ? 216 SER J OG 1 ATOM 6616 N N . THR D 2 210 ? -18.156 40.749 33.905 1.00 30.03 ? 217 THR J N 1 ATOM 6617 C CA . THR D 2 210 ? -17.585 42.065 33.855 1.00 19.40 ? 217 THR J CA 1 ATOM 6618 C C . THR D 2 210 ? -18.734 43.046 34.051 1.00 20.55 ? 217 THR J C 1 ATOM 6619 O O . THR D 2 210 ? -19.836 42.920 33.485 1.00 22.75 ? 217 THR J O 1 ATOM 6620 C CB . THR D 2 210 ? -16.947 42.187 32.501 1.00 14.59 ? 217 THR J CB 1 ATOM 6621 O OG1 . THR D 2 210 ? -16.061 41.098 32.317 1.00 12.86 ? 217 THR J OG1 1 ATOM 6622 C CG2 . THR D 2 210 ? -16.184 43.471 32.386 1.00 18.96 ? 217 THR J CG2 1 ATOM 6623 N N . LYS D 2 211 ? -18.438 44.058 34.844 1.00 16.08 ? 218 LYS J N 1 ATOM 6624 C CA . LYS D 2 211 ? -19.384 45.085 35.177 1.00 13.74 ? 218 LYS J CA 1 ATOM 6625 C C . LYS D 2 211 ? -18.472 46.278 35.300 1.00 13.03 ? 218 LYS J C 1 ATOM 6626 O O . LYS D 2 211 ? -17.468 46.250 36.021 1.00 20.49 ? 218 LYS J O 1 ATOM 6627 C CB . LYS D 2 211 ? -20.026 44.723 36.486 1.00 17.15 ? 218 LYS J CB 1 ATOM 6628 C CG . LYS D 2 211 ? -21.511 44.938 36.517 1.00 26.95 ? 218 LYS J CG 1 ATOM 6629 C CD . LYS D 2 211 ? -21.719 46.439 36.467 1.00 38.13 ? 218 LYS J CD 1 ATOM 6630 C CE . LYS D 2 211 ? -23.036 46.770 35.804 1.00 40.19 ? 218 LYS J CE 1 ATOM 6631 N NZ . LYS D 2 211 ? -23.111 48.203 35.703 1.00 39.67 ? 218 LYS J NZ 1 ATOM 6632 N N . VAL D 2 212 ? -18.759 47.289 34.523 1.00 7.90 ? 219 VAL J N 1 ATOM 6633 C CA . VAL D 2 212 ? -17.923 48.457 34.469 1.00 5.25 ? 219 VAL J CA 1 ATOM 6634 C C . VAL D 2 212 ? -18.882 49.629 34.583 1.00 11.89 ? 219 VAL J C 1 ATOM 6635 O O . VAL D 2 212 ? -20.050 49.506 34.190 1.00 15.28 ? 219 VAL J O 1 ATOM 6636 C CB . VAL D 2 212 ? -17.208 48.367 33.132 1.00 2.00 ? 219 VAL J CB 1 ATOM 6637 C CG1 . VAL D 2 212 ? -16.530 49.633 32.801 1.00 2.00 ? 219 VAL J CG1 1 ATOM 6638 C CG2 . VAL D 2 212 ? -16.086 47.353 33.206 1.00 2.00 ? 219 VAL J CG2 1 ATOM 6639 N N . ASP D 2 213 ? -18.470 50.758 35.156 1.00 11.40 ? 220 ASP J N 1 ATOM 6640 C CA . ASP D 2 213 ? -19.285 51.963 35.210 1.00 6.43 ? 220 ASP J CA 1 ATOM 6641 C C . ASP D 2 213 ? -18.321 53.031 34.789 1.00 13.17 ? 220 ASP J C 1 ATOM 6642 O O . ASP D 2 213 ? -17.183 53.043 35.290 1.00 21.06 ? 220 ASP J O 1 ATOM 6643 C CB . ASP D 2 213 ? -19.702 52.298 36.577 1.00 7.63 ? 220 ASP J CB 1 ATOM 6644 C CG . ASP D 2 213 ? -20.264 51.100 37.294 1.00 20.12 ? 220 ASP J CG 1 ATOM 6645 O OD1 . ASP D 2 213 ? -21.143 50.435 36.738 1.00 22.31 ? 220 ASP J OD1 1 ATOM 6646 O OD2 . ASP D 2 213 ? -19.795 50.826 38.404 1.00 28.91 ? 220 ASP J OD2 1 ATOM 6647 N N . LYS D 2 214 ? -18.647 53.909 33.846 1.00 12.44 ? 221 LYS J N 1 ATOM 6648 C CA . LYS D 2 214 ? -17.704 54.952 33.492 1.00 13.32 ? 221 LYS J CA 1 ATOM 6649 C C . LYS D 2 214 ? -18.308 56.314 33.754 1.00 16.40 ? 221 LYS J C 1 ATOM 6650 O O . LYS D 2 214 ? -19.391 56.573 33.189 1.00 20.81 ? 221 LYS J O 1 ATOM 6651 C CB . LYS D 2 214 ? -17.369 54.784 32.064 1.00 12.68 ? 221 LYS J CB 1 ATOM 6652 C CG . LYS D 2 214 ? -15.961 54.325 31.986 1.00 18.85 ? 221 LYS J CG 1 ATOM 6653 C CD . LYS D 2 214 ? -15.034 55.508 32.084 1.00 27.82 ? 221 LYS J CD 1 ATOM 6654 C CE . LYS D 2 214 ? -13.659 54.888 32.330 1.00 35.90 ? 221 LYS J CE 1 ATOM 6655 N NZ . LYS D 2 214 ? -12.636 55.903 32.556 1.00 40.55 ? 221 LYS J NZ 1 ATOM 6656 N N . LYS D 2 215 ? -17.750 57.167 34.644 1.00 13.18 ? 222 LYS J N 1 ATOM 6657 C CA . LYS D 2 215 ? -18.331 58.495 34.858 1.00 17.14 ? 222 LYS J CA 1 ATOM 6658 C C . LYS D 2 215 ? -17.993 59.256 33.612 1.00 21.71 ? 222 LYS J C 1 ATOM 6659 O O . LYS D 2 215 ? -16.814 59.220 33.225 1.00 30.33 ? 222 LYS J O 1 ATOM 6660 C CB . LYS D 2 215 ? -17.719 59.346 35.927 1.00 16.33 ? 222 LYS J CB 1 ATOM 6661 C CG . LYS D 2 215 ? -18.440 59.454 37.221 1.00 25.31 ? 222 LYS J CG 1 ATOM 6662 C CD . LYS D 2 215 ? -18.107 58.221 38.052 1.00 39.52 ? 222 LYS J CD 1 ATOM 6663 C CE . LYS D 2 215 ? -18.145 58.508 39.570 1.00 49.29 ? 222 LYS J CE 1 ATOM 6664 N NZ . LYS D 2 215 ? -19.477 58.465 40.170 1.00 55.21 ? 222 LYS J NZ 1 ATOM 6665 N N . ILE D 2 216 ? -18.971 59.877 32.955 1.00 18.08 ? 223 ILE J N 1 ATOM 6666 C CA . ILE D 2 216 ? -18.653 60.686 31.802 1.00 17.80 ? 223 ILE J CA 1 ATOM 6667 C C . ILE D 2 216 ? -18.247 62.014 32.438 1.00 22.31 ? 223 ILE J C 1 ATOM 6668 O O . ILE D 2 216 ? -19.013 62.628 33.194 1.00 21.29 ? 223 ILE J O 1 ATOM 6669 C CB . ILE D 2 216 ? -19.850 60.943 30.898 1.00 16.43 ? 223 ILE J CB 1 ATOM 6670 C CG1 . ILE D 2 216 ? -20.729 59.724 30.710 1.00 16.54 ? 223 ILE J CG1 1 ATOM 6671 C CG2 . ILE D 2 216 ? -19.281 61.409 29.557 1.00 19.28 ? 223 ILE J CG2 1 ATOM 6672 C CD1 . ILE D 2 216 ? -20.396 58.790 29.553 1.00 18.36 ? 223 ILE J CD1 1 ATOM 6673 N N . VAL D 2 217 ? -16.997 62.431 32.257 1.00 25.04 ? 226 VAL J N 1 ATOM 6674 C CA . VAL D 2 217 ? -16.572 63.722 32.770 1.00 27.40 ? 226 VAL J CA 1 ATOM 6675 C C . VAL D 2 217 ? -15.964 64.418 31.557 1.00 30.12 ? 226 VAL J C 1 ATOM 6676 O O . VAL D 2 217 ? -15.573 63.723 30.597 1.00 24.60 ? 226 VAL J O 1 ATOM 6677 C CB . VAL D 2 217 ? -15.510 63.625 33.933 1.00 29.34 ? 226 VAL J CB 1 ATOM 6678 C CG1 . VAL D 2 217 ? -15.913 62.538 34.917 1.00 32.62 ? 226 VAL J CG1 1 ATOM 6679 C CG2 . VAL D 2 217 ? -14.132 63.327 33.411 1.00 34.19 ? 226 VAL J CG2 1 ATOM 6680 N N . PRO D 2 218 ? -16.026 65.764 31.562 1.00 36.59 ? 227 PRO J N 1 ATOM 6681 C CA . PRO D 2 218 ? -15.591 66.608 30.451 1.00 38.21 ? 227 PRO J CA 1 ATOM 6682 C C . PRO D 2 218 ? -14.086 66.611 30.292 1.00 41.55 ? 227 PRO J C 1 ATOM 6683 O O . PRO D 2 218 ? -13.595 66.649 29.146 1.00 44.12 ? 227 PRO J O 1 ATOM 6684 C CB . PRO D 2 218 ? -16.174 67.970 30.795 1.00 38.47 ? 227 PRO J CB 1 ATOM 6685 C CG . PRO D 2 218 ? -16.242 68.010 32.312 1.00 35.13 ? 227 PRO J CG 1 ATOM 6686 C CD . PRO D 2 218 ? -16.660 66.586 32.619 1.00 36.71 ? 227 PRO J CD 1 HETATM 6687 C C1 . NAG E 3 . ? -20.038 2.771 41.001 1.00 34.92 ? 901 NAG L C1 1 HETATM 6688 C C2 . NAG E 3 . ? -20.943 1.838 40.245 1.00 38.79 ? 901 NAG L C2 1 HETATM 6689 C C3 . NAG E 3 . ? -20.049 0.773 39.609 1.00 39.67 ? 901 NAG L C3 1 HETATM 6690 C C4 . NAG E 3 . ? -19.133 1.420 38.569 1.00 39.32 ? 901 NAG L C4 1 HETATM 6691 C C5 . NAG E 3 . ? -18.403 2.644 39.204 1.00 37.31 ? 901 NAG L C5 1 HETATM 6692 C C6 . NAG E 3 . ? -17.828 3.588 38.144 1.00 40.04 ? 901 NAG L C6 1 HETATM 6693 C C7 . NAG E 3 . ? -21.699 0.429 42.065 1.00 48.73 ? 901 NAG L C7 1 HETATM 6694 C C8 . NAG E 3 . ? -22.881 -0.149 42.824 1.00 46.67 ? 901 NAG L C8 1 HETATM 6695 N N2 . NAG E 3 . ? -21.983 1.245 41.058 1.00 41.97 ? 901 NAG L N2 1 HETATM 6696 O O3 . NAG E 3 . ? -20.869 -0.208 38.989 1.00 43.33 ? 901 NAG L O3 1 HETATM 6697 O O4 . NAG E 3 . ? -18.199 0.419 38.110 1.00 36.69 ? 901 NAG L O4 1 HETATM 6698 O O5 . NAG E 3 . ? -19.297 3.434 39.984 1.00 32.70 ? 901 NAG L O5 1 HETATM 6699 O O6 . NAG E 3 . ? -18.885 4.194 37.410 1.00 47.71 ? 901 NAG L O6 1 HETATM 6700 O O7 . NAG E 3 . ? -20.518 0.183 42.373 1.00 54.60 ? 901 NAG L O7 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ASP 1 1 1 ASP ASP L . n A 1 2 VAL 2 2 2 VAL VAL L . n A 1 3 LEU 3 3 3 LEU LEU L . n A 1 4 MET 4 4 4 MET MET L . n A 1 5 THR 5 5 5 THR THR L . n A 1 6 GLN 6 6 6 GLN GLN L . n A 1 7 THR 7 7 7 THR THR L . n A 1 8 PRO 8 8 8 PRO PRO L . n A 1 9 LEU 9 9 9 LEU LEU L . n A 1 10 SER 10 10 10 SER SER L . n A 1 11 LEU 11 11 11 LEU LEU L . n A 1 12 PRO 12 12 12 PRO PRO L . n A 1 13 VAL 13 13 13 VAL VAL L . n A 1 14 SER 14 14 14 SER SER L . n A 1 15 LEU 15 15 15 LEU LEU L . n A 1 16 GLY 16 16 16 GLY GLY L . n A 1 17 ASP 17 17 17 ASP ASP L . n A 1 18 GLN 18 18 18 GLN GLN L . n A 1 19 ALA 19 19 19 ALA ALA L . n A 1 20 SER 20 20 20 SER SER L . n A 1 21 ILE 21 21 21 ILE ILE L . n A 1 22 SER 22 22 22 SER SER L . n A 1 23 CYS 23 23 23 CYS CYS L . n A 1 24 ARG 24 24 24 ARG ARG L . n A 1 25 SER 25 25 25 SER SER L . n A 1 26 ASN 26 26 26 ASN ASN L . n A 1 27 GLN 27 27 27 GLN GLN L . n A 1 28 THR 28 27 27 THR THR L A n A 1 29 ILE 29 27 27 ILE ILE L B n A 1 30 LEU 30 27 27 LEU LEU L C n A 1 31 LEU 31 27 27 LEU LEU L D n A 1 32 SER 32 27 27 SER SER L E n A 1 33 ASP 33 28 28 ASP ASP L . n A 1 34 GLY 34 29 29 GLY GLY L . n A 1 35 ASP 35 30 30 ASP ASP L . n A 1 36 THR 36 31 31 THR THR L . n A 1 37 TYR 37 32 32 TYR TYR L . n A 1 38 LEU 38 33 33 LEU LEU L . n A 1 39 GLU 39 34 34 GLU GLU L . n A 1 40 TRP 40 35 35 TRP TRP L . n A 1 41 TYR 41 36 36 TYR TYR L . n A 1 42 LEU 42 37 37 LEU LEU L . n A 1 43 GLN 43 38 38 GLN GLN L . n A 1 44 LYS 44 39 39 LYS LYS L . n A 1 45 PRO 45 40 40 PRO PRO L . n A 1 46 GLY 46 41 41 GLY GLY L . n A 1 47 GLN 47 42 42 GLN GLN L . n A 1 48 SER 48 43 43 SER SER L . n A 1 49 PRO 49 44 44 PRO PRO L . n A 1 50 LYS 50 45 45 LYS LYS L . n A 1 51 LEU 51 46 46 LEU LEU L . n A 1 52 LEU 52 47 47 LEU LEU L . n A 1 53 ILE 53 48 48 ILE ILE L . n A 1 54 TYR 54 49 49 TYR TYR L . n A 1 55 LYS 55 50 50 LYS LYS L . n A 1 56 VAL 56 51 51 VAL VAL L . n A 1 57 SER 57 52 52 SER SER L . n A 1 58 ASN 58 53 53 ASN ASN L . n A 1 59 ARG 59 54 54 ARG ARG L . n A 1 60 PHE 60 55 55 PHE PHE L . n A 1 61 SER 61 56 56 SER SER L . n A 1 62 GLY 62 57 57 GLY GLY L . n A 1 63 VAL 63 58 58 VAL VAL L . n A 1 64 PRO 64 59 59 PRO PRO L . n A 1 65 ASP 65 60 60 ASP ASP L . n A 1 66 ARG 66 61 61 ARG ARG L . n A 1 67 PHE 67 62 62 PHE PHE L . n A 1 68 SER 68 63 63 SER SER L . n A 1 69 GLY 69 64 64 GLY GLY L . n A 1 70 SER 70 65 65 SER SER L . n A 1 71 GLY 71 66 66 GLY GLY L . n A 1 72 SER 72 67 67 SER SER L . n A 1 73 GLY 73 68 68 GLY GLY L . n A 1 74 THR 74 69 69 THR THR L . n A 1 75 ASP 75 70 70 ASP ASP L . n A 1 76 PHE 76 71 71 PHE PHE L . n A 1 77 THR 77 72 72 THR THR L . n A 1 78 LEU 78 73 73 LEU LEU L . n A 1 79 LYS 79 74 74 LYS LYS L . n A 1 80 ILE 80 75 75 ILE ILE L . n A 1 81 SER 81 76 76 SER SER L . n A 1 82 ARG 82 77 77 ARG ARG L . n A 1 83 VAL 83 78 78 VAL VAL L . n A 1 84 GLU 84 79 79 GLU GLU L . n A 1 85 ALA 85 80 80 ALA ALA L . n A 1 86 GLU 86 81 81 GLU GLU L . n A 1 87 ASP 87 82 82 ASP ASP L . n A 1 88 LEU 88 83 83 LEU LEU L . n A 1 89 GLY 89 84 84 GLY GLY L . n A 1 90 VAL 90 85 85 VAL VAL L . n A 1 91 TYR 91 86 86 TYR TYR L . n A 1 92 TYR 92 87 87 TYR TYR L . n A 1 93 CYS 93 88 88 CYS CYS L . n A 1 94 PHE 94 89 89 PHE PHE L . n A 1 95 GLN 95 90 90 GLN GLN L . n A 1 96 GLY 96 91 91 GLY GLY L . n A 1 97 SER 97 92 92 SER SER L . n A 1 98 HIS 98 93 93 HIS HIS L . n A 1 99 VAL 99 94 94 VAL VAL L . n A 1 100 PRO 100 95 95 PRO PRO L . n A 1 101 PRO 101 96 96 PRO PRO L . n A 1 102 THR 102 97 97 THR THR L . n A 1 103 PHE 103 98 98 PHE PHE L . n A 1 104 GLY 104 99 99 GLY GLY L . n A 1 105 GLY 105 100 100 GLY GLY L . n A 1 106 GLY 106 101 101 GLY GLY L . n A 1 107 THR 107 102 102 THR THR L . n A 1 108 LYS 108 103 103 LYS LYS L . n A 1 109 LEU 109 104 104 LEU LEU L . n A 1 110 GLU 110 105 105 GLU GLU L . n A 1 111 ILE 111 106 106 ILE ILE L . n A 1 112 LYS 112 107 107 LYS LYS L . n A 1 113 ARG 113 108 108 ARG ARG L . n A 1 114 ALA 114 109 109 ALA ALA L . n A 1 115 ASP 115 110 110 ASP ASP L . n A 1 116 ALA 116 111 111 ALA ALA L . n A 1 117 ALA 117 112 112 ALA ALA L . n A 1 118 PRO 118 113 113 PRO PRO L . n A 1 119 THR 119 114 114 THR THR L . n A 1 120 VAL 120 115 115 VAL VAL L . n A 1 121 SER 121 116 116 SER SER L . n A 1 122 ILE 122 117 117 ILE ILE L . n A 1 123 PHE 123 118 118 PHE PHE L . n A 1 124 PRO 124 119 119 PRO PRO L . n A 1 125 PRO 125 120 120 PRO PRO L . n A 1 126 SER 126 121 121 SER SER L . n A 1 127 SER 127 122 122 SER SER L . n A 1 128 GLU 128 123 123 GLU GLU L . n A 1 129 GLN 129 124 124 GLN GLN L . n A 1 130 LEU 130 125 125 LEU LEU L . n A 1 131 THR 131 126 126 THR THR L . n A 1 132 SER 132 127 127 SER SER L . n A 1 133 GLY 133 128 128 GLY GLY L . n A 1 134 GLY 134 129 129 GLY GLY L . n A 1 135 ALA 135 130 130 ALA ALA L . n A 1 136 SER 136 131 131 SER SER L . n A 1 137 VAL 137 132 132 VAL VAL L . n A 1 138 VAL 138 133 133 VAL VAL L . n A 1 139 CYS 139 134 134 CYS CYS L . n A 1 140 PHE 140 135 135 PHE PHE L . n A 1 141 LEU 141 136 136 LEU LEU L . n A 1 142 ASN 142 137 137 ASN ASN L . n A 1 143 ASN 143 138 138 ASN ASN L . n A 1 144 PHE 144 139 139 PHE PHE L . n A 1 145 TYR 145 140 140 TYR TYR L . n A 1 146 PRO 146 141 141 PRO PRO L . n A 1 147 LYS 147 142 142 LYS LYS L . n A 1 148 ASP 148 143 143 ASP ASP L . n A 1 149 ILE 149 144 144 ILE ILE L . n A 1 150 ASN 150 145 145 ASN ASN L . n A 1 151 VAL 151 146 146 VAL VAL L . n A 1 152 LYS 152 147 147 LYS LYS L . n A 1 153 TRP 153 148 148 TRP TRP L . n A 1 154 LYS 154 149 149 LYS LYS L . n A 1 155 ILE 155 150 150 ILE ILE L . n A 1 156 ASP 156 151 151 ASP ASP L . n A 1 157 GLY 157 152 152 GLY GLY L . n A 1 158 SER 158 153 153 SER SER L . n A 1 159 GLU 159 154 154 GLU GLU L . n A 1 160 ARG 160 155 155 ARG ARG L . n A 1 161 GLN 161 156 156 GLN GLN L . n A 1 162 ASN 162 157 157 ASN ASN L . n A 1 163 GLY 163 158 158 GLY GLY L . n A 1 164 VAL 164 159 159 VAL VAL L . n A 1 165 LEU 165 160 160 LEU LEU L . n A 1 166 ASN 166 161 161 ASN ASN L . n A 1 167 SER 167 162 162 SER SER L . n A 1 168 TRP 168 163 163 TRP TRP L . n A 1 169 THR 169 164 164 THR THR L . n A 1 170 ASP 170 165 165 ASP ASP L . n A 1 171 GLN 171 166 166 GLN GLN L . n A 1 172 ASP 172 167 167 ASP ASP L . n A 1 173 SER 173 168 168 SER SER L . n A 1 174 LYS 174 169 169 LYS LYS L . n A 1 175 ASP 175 170 170 ASP ASP L . n A 1 176 SER 176 171 171 SER SER L . n A 1 177 THR 177 172 172 THR THR L . n A 1 178 TYR 178 173 173 TYR TYR L . n A 1 179 SER 179 174 174 SER SER L . n A 1 180 MET 180 175 175 MET MET L . n A 1 181 SER 181 176 176 SER SER L . n A 1 182 SER 182 177 177 SER SER L . n A 1 183 THR 183 178 178 THR THR L . n A 1 184 LEU 184 179 179 LEU LEU L . n A 1 185 THR 185 180 180 THR THR L . n A 1 186 LEU 186 181 181 LEU LEU L . n A 1 187 THR 187 182 182 THR THR L . n A 1 188 LYS 188 183 183 LYS LYS L . n A 1 189 ASP 189 184 184 ASP ASP L . n A 1 190 GLU 190 185 185 GLU GLU L . n A 1 191 TYR 191 186 186 TYR TYR L . n A 1 192 GLU 192 187 187 GLU GLU L . n A 1 193 ARG 193 188 188 ARG ARG L . n A 1 194 HIS 194 189 189 HIS HIS L . n A 1 195 ASN 195 190 190 ASN ASN L . n A 1 196 SER 196 191 191 SER SER L . n A 1 197 TYR 197 192 192 TYR TYR L . n A 1 198 THR 198 193 193 THR THR L . n A 1 199 CYS 199 194 194 CYS CYS L . n A 1 200 GLU 200 195 195 GLU GLU L . n A 1 201 ALA 201 196 196 ALA ALA L . n A 1 202 THR 202 197 197 THR THR L . n A 1 203 HIS 203 198 198 HIS HIS L . n A 1 204 LYS 204 199 199 LYS LYS L . n A 1 205 THR 205 200 200 THR THR L . n A 1 206 SER 206 201 201 SER SER L . n A 1 207 THR 207 202 202 THR THR L . n A 1 208 SER 208 203 203 SER SER L . n A 1 209 PRO 209 204 204 PRO PRO L . n A 1 210 ILE 210 205 205 ILE ILE L . n A 1 211 VAL 211 206 206 VAL VAL L . n A 1 212 LYS 212 207 207 LYS LYS L . n A 1 213 SER 213 208 208 SER SER L . n A 1 214 PHE 214 209 209 PHE PHE L . n A 1 215 ASN 215 210 210 ASN ASN L . n A 1 216 ARG 216 211 211 ARG ARG L . n A 1 217 ASN 217 212 212 ASN ASN L . n A 1 218 GLU 218 213 213 GLU GLU L . n A 1 219 CYS 219 214 214 CYS CYS L . n B 2 1 GLU 1 1 1 GLU GLU H . n B 2 2 VAL 2 2 2 VAL VAL H . n B 2 3 GLN 3 3 3 GLN GLN H . n B 2 4 LEU 4 4 4 LEU LEU H . n B 2 5 VAL 5 5 5 VAL VAL H . n B 2 6 GLU 6 6 6 GLU GLU H . n B 2 7 SER 7 7 7 SER SER H . n B 2 8 GLY 8 8 8 GLY GLY H . n B 2 9 GLY 9 9 9 GLY GLY H . n B 2 10 ASP 10 10 10 ASP ASP H . n B 2 11 LEU 11 11 11 LEU LEU H . n B 2 12 VAL 12 12 12 VAL VAL H . n B 2 13 LYS 13 13 13 LYS LYS H . n B 2 14 PRO 14 14 14 PRO PRO H . n B 2 15 GLY 15 15 15 GLY GLY H . n B 2 16 GLY 16 16 16 GLY GLY H . n B 2 17 SER 17 17 17 SER SER H . n B 2 18 LEU 18 18 18 LEU LEU H . n B 2 19 LYS 19 19 19 LYS LYS H . n B 2 20 LEU 20 20 20 LEU LEU H . n B 2 21 SER 21 21 21 SER SER H . n B 2 22 CYS 22 22 22 CYS CYS H . n B 2 23 ALA 23 23 23 ALA ALA H . n B 2 24 ALA 24 24 24 ALA ALA H . n B 2 25 SER 25 25 25 SER SER H . n B 2 26 GLY 26 26 26 GLY GLY H . n B 2 27 PHE 27 27 27 PHE PHE H . n B 2 28 THR 28 28 28 THR THR H . n B 2 29 PHE 29 29 29 PHE PHE H . n B 2 30 SER 30 30 30 SER SER H . n B 2 31 ARG 31 31 31 ARG ARG H . n B 2 32 CYS 32 32 32 CYS CYS H . n B 2 33 ALA 33 33 33 ALA ALA H . n B 2 34 MET 34 34 34 MET MET H . n B 2 35 SER 35 35 35 SER SER H . n B 2 36 TRP 36 36 36 TRP TRP H . n B 2 37 VAL 37 37 37 VAL VAL H . n B 2 38 ARG 38 38 38 ARG ARG H . n B 2 39 GLN 39 39 39 GLN GLN H . n B 2 40 THR 40 40 40 THR THR H . n B 2 41 PRO 41 41 41 PRO PRO H . n B 2 42 GLU 42 42 42 GLU GLU H . n B 2 43 LYS 43 43 43 LYS LYS H . n B 2 44 ARG 44 44 44 ARG ARG H . n B 2 45 LEU 45 45 45 LEU LEU H . n B 2 46 GLU 46 46 46 GLU GLU H . n B 2 47 TRP 47 47 47 TRP TRP H . n B 2 48 VAL 48 48 48 VAL VAL H . n B 2 49 ALA 49 49 49 ALA ALA H . n B 2 50 GLY 50 50 50 GLY GLY H . n B 2 51 ILE 51 51 51 ILE ILE H . n B 2 52 SER 52 52 52 SER SER H . n B 2 53 SER 53 52 52 SER SER H A n B 2 54 GLY 54 53 53 GLY GLY H . n B 2 55 GLY 55 54 54 GLY GLY H . n B 2 56 SER 56 55 55 SER SER H . n B 2 57 TYR 57 56 56 TYR TYR H . n B 2 58 THR 58 57 57 THR THR H . n B 2 59 PHE 59 58 58 PHE PHE H . n B 2 60 TYR 60 59 59 TYR TYR H . n B 2 61 PRO 61 60 60 PRO PRO H . n B 2 62 ASP 62 61 61 ASP ASP H . n B 2 63 THR 63 62 62 THR THR H . n B 2 64 VAL 64 63 63 VAL VAL H . n B 2 65 LYS 65 64 64 LYS LYS H . n B 2 66 GLY 66 65 65 GLY GLY H . n B 2 67 ARG 67 66 66 ARG ARG H . n B 2 68 PHE 68 67 67 PHE PHE H . n B 2 69 ILE 69 68 68 ILE ILE H . n B 2 70 ILE 70 69 69 ILE ILE H . n B 2 71 SER 71 70 70 SER SER H . n B 2 72 ARG 72 71 71 ARG ARG H . n B 2 73 ASN 73 72 72 ASN ASN H . n B 2 74 ASN 74 73 73 ASN ASN H . n B 2 75 ALA 75 74 74 ALA ALA H . n B 2 76 ARG 76 75 75 ARG ARG H . n B 2 77 ASN 77 76 76 ASN ASN H . n B 2 78 THR 78 77 77 THR THR H . n B 2 79 LEU 79 78 78 LEU LEU H . n B 2 80 SER 80 79 79 SER SER H . n B 2 81 LEU 81 80 80 LEU LEU H . n B 2 82 GLN 82 81 81 GLN GLN H . n B 2 83 MET 83 82 82 MET MET H . n B 2 84 SER 84 82 82 SER SER H A n B 2 85 SER 85 82 82 SER SER H B n B 2 86 LEU 86 82 82 LEU LEU H C n B 2 87 ARG 87 83 83 ARG ARG H . n B 2 88 SER 88 84 84 SER SER H . n B 2 89 GLU 89 85 85 GLU GLU H . n B 2 90 ASP 90 86 86 ASP ASP H . n B 2 91 THR 91 87 87 THR THR H . n B 2 92 ALA 92 88 88 ALA ALA H . n B 2 93 ILE 93 89 89 ILE ILE H . n B 2 94 TYR 94 90 90 TYR TYR H . n B 2 95 TYR 95 91 91 TYR TYR H . n B 2 96 CYS 96 92 92 CYS CYS H . n B 2 97 THR 97 93 93 THR THR H . n B 2 98 ARG 98 94 94 ARG ARG H . n B 2 99 TYR 99 95 95 TYR TYR H . n B 2 100 SER 100 96 96 SER SER H . n B 2 101 SER 101 97 97 SER SER H . n B 2 102 ASP 102 98 98 ASP ASP H . n B 2 103 PRO 103 99 99 PRO PRO H . n B 2 104 PHE 104 100 100 PHE PHE H . n B 2 105 TYR 105 100 100 TYR TYR H B n B 2 106 PHE 106 100 100 PHE PHE H C n B 2 107 ASP 107 101 101 ASP ASP H . n B 2 108 TYR 108 102 102 TYR TYR H . n B 2 109 TRP 109 103 103 TRP TRP H . n B 2 110 GLY 110 104 104 GLY GLY H . n B 2 111 GLN 111 105 105 GLN GLN H . n B 2 112 GLY 112 106 106 GLY GLY H . n B 2 113 THR 113 107 107 THR THR H . n B 2 114 THR 114 108 108 THR THR H . n B 2 115 LEU 115 109 109 LEU LEU H . n B 2 116 THR 116 110 110 THR THR H . n B 2 117 VAL 117 111 111 VAL VAL H . n B 2 118 SER 118 112 112 SER SER H . n B 2 119 SER 119 113 113 SER SER H . n B 2 120 ALA 120 114 114 ALA ALA H . n B 2 121 LYS 121 115 115 LYS LYS H . n B 2 122 THR 122 116 116 THR THR H . n B 2 123 THR 123 117 117 THR THR H . n B 2 124 PRO 124 118 118 PRO PRO H . n B 2 125 PRO 125 119 119 PRO PRO H . n B 2 126 SER 126 120 120 SER SER H . n B 2 127 VAL 127 121 121 VAL VAL H . n B 2 128 TYR 128 122 122 TYR TYR H . n B 2 129 PRO 129 123 123 PRO PRO H . n B 2 130 LEU 130 124 124 LEU LEU H . n B 2 131 ALA 131 125 125 ALA ALA H . n B 2 132 PRO 132 126 126 PRO PRO H . n B 2 133 GLY 133 127 127 GLY GLY H . n B 2 134 SER 134 128 128 SER SER H . n B 2 135 ALA 135 129 129 ALA ALA H . n B 2 136 ALA 136 130 130 ALA ALA H . n B 2 137 GLN 137 133 133 GLN GLN H . n B 2 138 THR 138 134 134 THR THR H . n B 2 139 ASN 139 135 135 ASN ASN H . n B 2 140 SER 140 136 136 SER SER H . n B 2 141 MET 141 137 137 MET MET H . n B 2 142 VAL 142 138 138 VAL VAL H . n B 2 143 THR 143 139 139 THR THR H . n B 2 144 LEU 144 140 140 LEU LEU H . n B 2 145 GLY 145 141 141 GLY GLY H . n B 2 146 CYS 146 142 142 CYS CYS H . n B 2 147 LEU 147 143 143 LEU LEU H . n B 2 148 VAL 148 144 144 VAL VAL H . n B 2 149 LYS 149 145 145 LYS LYS H . n B 2 150 GLY 150 146 146 GLY GLY H . n B 2 151 TYR 151 147 147 TYR TYR H . n B 2 152 PHE 152 148 148 PHE PHE H . n B 2 153 PRO 153 149 149 PRO PRO H . n B 2 154 GLU 154 150 150 GLU GLU H . n B 2 155 PRO 155 151 151 PRO PRO H . n B 2 156 VAL 156 152 152 VAL VAL H . n B 2 157 THR 157 153 153 THR THR H . n B 2 158 VAL 158 154 154 VAL VAL H . n B 2 159 THR 159 156 156 THR THR H . n B 2 160 TRP 160 157 157 TRP TRP H . n B 2 161 ASN 161 162 162 ASN ASN H . n B 2 162 SER 162 163 163 SER SER H . n B 2 163 GLY 163 164 164 GLY GLY H . n B 2 164 SER 164 165 165 SER SER H . n B 2 165 LEU 165 166 166 LEU LEU H . n B 2 166 SER 166 167 167 SER SER H . n B 2 167 SER 167 168 168 SER SER H . n B 2 168 GLY 168 169 169 GLY GLY H . n B 2 169 VAL 169 171 171 VAL VAL H . n B 2 170 HIS 170 172 172 HIS HIS H . n B 2 171 THR 171 173 173 THR THR H . n B 2 172 PHE 172 174 174 PHE PHE H . n B 2 173 PRO 173 175 175 PRO PRO H . n B 2 174 ALA 174 176 176 ALA ALA H . n B 2 175 VAL 175 177 177 VAL VAL H . n B 2 176 LEU 176 178 178 LEU LEU H . n B 2 177 GLN 177 179 179 GLN GLN H . n B 2 178 SER 178 180 180 SER SER H . n B 2 179 ASP 179 183 183 ASP ASP H . n B 2 180 LEU 180 184 184 LEU LEU H . n B 2 181 TYR 181 185 185 TYR TYR H . n B 2 182 THR 182 186 186 THR THR H . n B 2 183 LEU 183 187 187 LEU LEU H . n B 2 184 SER 184 188 188 SER SER H . n B 2 185 SER 185 189 189 SER SER H . n B 2 186 SER 186 190 190 SER SER H . n B 2 187 VAL 187 191 191 VAL VAL H . n B 2 188 THR 188 192 192 THR THR H . n B 2 189 VAL 189 193 193 VAL VAL H . n B 2 190 PRO 190 194 194 PRO PRO H . n B 2 191 SER 191 195 195 SER SER H . n B 2 192 SER 192 196 196 SER SER H . n B 2 193 PRO 193 198 198 PRO PRO H . n B 2 194 ARG 194 199 199 ARG ARG H . n B 2 195 PRO 195 200 200 PRO PRO H . n B 2 196 SER 196 202 202 SER SER H . n B 2 197 GLU 197 203 203 GLU GLU H . n B 2 198 THR 198 204 204 THR THR H . n B 2 199 VAL 199 205 205 VAL VAL H . n B 2 200 THR 200 206 206 THR THR H . n B 2 201 CYS 201 208 208 CYS CYS H . n B 2 202 ASN 202 209 209 ASN ASN H . n B 2 203 VAL 203 210 210 VAL VAL H . n B 2 204 ALA 204 211 211 ALA ALA H . n B 2 205 HIS 205 212 212 HIS HIS H . n B 2 206 PRO 206 213 213 PRO PRO H . n B 2 207 ALA 207 214 214 ALA ALA H . n B 2 208 SER 208 215 215 SER SER H . n B 2 209 SER 209 216 216 SER SER H . n B 2 210 THR 210 217 217 THR THR H . n B 2 211 LYS 211 218 218 LYS LYS H . n B 2 212 VAL 212 219 219 VAL VAL H . n B 2 213 ASP 213 220 220 ASP ASP H . n B 2 214 LYS 214 221 221 LYS LYS H . n B 2 215 LYS 215 222 222 LYS LYS H . n B 2 216 ILE 216 223 223 ILE ILE H . n B 2 217 VAL 217 226 226 VAL VAL H . n B 2 218 PRO 218 227 227 PRO PRO H . n B 2 219 ARG 219 228 ? ? ? H . n B 2 220 ASP 220 229 ? ? ? H . n B 2 221 CYS 221 230 ? ? ? H . n C 1 1 ASP 1 1 1 ASP ASP M . n C 1 2 VAL 2 2 2 VAL VAL M . n C 1 3 LEU 3 3 3 LEU LEU M . n C 1 4 MET 4 4 4 MET MET M . n C 1 5 THR 5 5 5 THR THR M . n C 1 6 GLN 6 6 6 GLN GLN M . n C 1 7 THR 7 7 7 THR THR M . n C 1 8 PRO 8 8 8 PRO PRO M . n C 1 9 LEU 9 9 9 LEU LEU M . n C 1 10 SER 10 10 10 SER SER M . n C 1 11 LEU 11 11 11 LEU LEU M . n C 1 12 PRO 12 12 12 PRO PRO M . n C 1 13 VAL 13 13 13 VAL VAL M . n C 1 14 SER 14 14 14 SER SER M . n C 1 15 LEU 15 15 15 LEU LEU M . n C 1 16 GLY 16 16 16 GLY GLY M . n C 1 17 ASP 17 17 17 ASP ASP M . n C 1 18 GLN 18 18 18 GLN GLN M . n C 1 19 ALA 19 19 19 ALA ALA M . n C 1 20 SER 20 20 20 SER SER M . n C 1 21 ILE 21 21 21 ILE ILE M . n C 1 22 SER 22 22 22 SER SER M . n C 1 23 CYS 23 23 23 CYS CYS M . n C 1 24 ARG 24 24 24 ARG ARG M . n C 1 25 SER 25 25 25 SER SER M . n C 1 26 ASN 26 26 26 ASN ASN M . n C 1 27 GLN 27 27 27 GLN GLN M . n C 1 28 THR 28 27 27 THR THR M A n C 1 29 ILE 29 27 27 ILE ILE M B n C 1 30 LEU 30 27 27 LEU LEU M C n C 1 31 LEU 31 27 27 LEU LEU M D n C 1 32 SER 32 27 27 SER SER M E n C 1 33 ASP 33 28 28 ASP ASP M . n C 1 34 GLY 34 29 29 GLY GLY M . n C 1 35 ASP 35 30 30 ASP ASP M . n C 1 36 THR 36 31 31 THR THR M . n C 1 37 TYR 37 32 32 TYR TYR M . n C 1 38 LEU 38 33 33 LEU LEU M . n C 1 39 GLU 39 34 34 GLU GLU M . n C 1 40 TRP 40 35 35 TRP TRP M . n C 1 41 TYR 41 36 36 TYR TYR M . n C 1 42 LEU 42 37 37 LEU LEU M . n C 1 43 GLN 43 38 38 GLN GLN M . n C 1 44 LYS 44 39 39 LYS LYS M . n C 1 45 PRO 45 40 40 PRO PRO M . n C 1 46 GLY 46 41 41 GLY GLY M . n C 1 47 GLN 47 42 42 GLN GLN M . n C 1 48 SER 48 43 43 SER SER M . n C 1 49 PRO 49 44 44 PRO PRO M . n C 1 50 LYS 50 45 45 LYS LYS M . n C 1 51 LEU 51 46 46 LEU LEU M . n C 1 52 LEU 52 47 47 LEU LEU M . n C 1 53 ILE 53 48 48 ILE ILE M . n C 1 54 TYR 54 49 49 TYR TYR M . n C 1 55 LYS 55 50 50 LYS LYS M . n C 1 56 VAL 56 51 51 VAL VAL M . n C 1 57 SER 57 52 52 SER SER M . n C 1 58 ASN 58 53 53 ASN ASN M . n C 1 59 ARG 59 54 54 ARG ARG M . n C 1 60 PHE 60 55 55 PHE PHE M . n C 1 61 SER 61 56 56 SER SER M . n C 1 62 GLY 62 57 57 GLY GLY M . n C 1 63 VAL 63 58 58 VAL VAL M . n C 1 64 PRO 64 59 59 PRO PRO M . n C 1 65 ASP 65 60 60 ASP ASP M . n C 1 66 ARG 66 61 61 ARG ARG M . n C 1 67 PHE 67 62 62 PHE PHE M . n C 1 68 SER 68 63 63 SER SER M . n C 1 69 GLY 69 64 64 GLY GLY M . n C 1 70 SER 70 65 65 SER SER M . n C 1 71 GLY 71 66 66 GLY GLY M . n C 1 72 SER 72 67 67 SER SER M . n C 1 73 GLY 73 68 68 GLY GLY M . n C 1 74 THR 74 69 69 THR THR M . n C 1 75 ASP 75 70 70 ASP ASP M . n C 1 76 PHE 76 71 71 PHE PHE M . n C 1 77 THR 77 72 72 THR THR M . n C 1 78 LEU 78 73 73 LEU LEU M . n C 1 79 LYS 79 74 74 LYS LYS M . n C 1 80 ILE 80 75 75 ILE ILE M . n C 1 81 SER 81 76 76 SER SER M . n C 1 82 ARG 82 77 77 ARG ARG M . n C 1 83 VAL 83 78 78 VAL VAL M . n C 1 84 GLU 84 79 79 GLU GLU M . n C 1 85 ALA 85 80 80 ALA ALA M . n C 1 86 GLU 86 81 81 GLU GLU M . n C 1 87 ASP 87 82 82 ASP ASP M . n C 1 88 LEU 88 83 83 LEU LEU M . n C 1 89 GLY 89 84 84 GLY GLY M . n C 1 90 VAL 90 85 85 VAL VAL M . n C 1 91 TYR 91 86 86 TYR TYR M . n C 1 92 TYR 92 87 87 TYR TYR M . n C 1 93 CYS 93 88 88 CYS CYS M . n C 1 94 PHE 94 89 89 PHE PHE M . n C 1 95 GLN 95 90 90 GLN GLN M . n C 1 96 GLY 96 91 91 GLY GLY M . n C 1 97 SER 97 92 92 SER SER M . n C 1 98 HIS 98 93 93 HIS HIS M . n C 1 99 VAL 99 94 94 VAL VAL M . n C 1 100 PRO 100 95 95 PRO PRO M . n C 1 101 PRO 101 96 96 PRO PRO M . n C 1 102 THR 102 97 97 THR THR M . n C 1 103 PHE 103 98 98 PHE PHE M . n C 1 104 GLY 104 99 99 GLY GLY M . n C 1 105 GLY 105 100 100 GLY GLY M . n C 1 106 GLY 106 101 101 GLY GLY M . n C 1 107 THR 107 102 102 THR THR M . n C 1 108 LYS 108 103 103 LYS LYS M . n C 1 109 LEU 109 104 104 LEU LEU M . n C 1 110 GLU 110 105 105 GLU GLU M . n C 1 111 ILE 111 106 106 ILE ILE M . n C 1 112 LYS 112 107 107 LYS LYS M . n C 1 113 ARG 113 108 108 ARG ARG M . n C 1 114 ALA 114 109 109 ALA ALA M . n C 1 115 ASP 115 110 110 ASP ASP M . n C 1 116 ALA 116 111 111 ALA ALA M . n C 1 117 ALA 117 112 112 ALA ALA M . n C 1 118 PRO 118 113 113 PRO PRO M . n C 1 119 THR 119 114 114 THR THR M . n C 1 120 VAL 120 115 115 VAL VAL M . n C 1 121 SER 121 116 116 SER SER M . n C 1 122 ILE 122 117 117 ILE ILE M . n C 1 123 PHE 123 118 118 PHE PHE M . n C 1 124 PRO 124 119 119 PRO PRO M . n C 1 125 PRO 125 120 120 PRO PRO M . n C 1 126 SER 126 121 121 SER SER M . n C 1 127 SER 127 122 122 SER SER M . n C 1 128 GLU 128 123 123 GLU GLU M . n C 1 129 GLN 129 124 124 GLN GLN M . n C 1 130 LEU 130 125 125 LEU LEU M . n C 1 131 THR 131 126 126 THR THR M . n C 1 132 SER 132 127 127 SER SER M . n C 1 133 GLY 133 128 128 GLY GLY M . n C 1 134 GLY 134 129 129 GLY GLY M . n C 1 135 ALA 135 130 130 ALA ALA M . n C 1 136 SER 136 131 131 SER SER M . n C 1 137 VAL 137 132 132 VAL VAL M . n C 1 138 VAL 138 133 133 VAL VAL M . n C 1 139 CYS 139 134 134 CYS CYS M . n C 1 140 PHE 140 135 135 PHE PHE M . n C 1 141 LEU 141 136 136 LEU LEU M . n C 1 142 ASN 142 137 137 ASN ASN M . n C 1 143 ASN 143 138 138 ASN ASN M . n C 1 144 PHE 144 139 139 PHE PHE M . n C 1 145 TYR 145 140 140 TYR TYR M . n C 1 146 PRO 146 141 141 PRO PRO M . n C 1 147 LYS 147 142 142 LYS LYS M . n C 1 148 ASP 148 143 143 ASP ASP M . n C 1 149 ILE 149 144 144 ILE ILE M . n C 1 150 ASN 150 145 145 ASN ASN M . n C 1 151 VAL 151 146 146 VAL VAL M . n C 1 152 LYS 152 147 147 LYS LYS M . n C 1 153 TRP 153 148 148 TRP TRP M . n C 1 154 LYS 154 149 149 LYS LYS M . n C 1 155 ILE 155 150 150 ILE ILE M . n C 1 156 ASP 156 151 151 ASP ASP M . n C 1 157 GLY 157 152 152 GLY GLY M . n C 1 158 SER 158 153 153 SER SER M . n C 1 159 GLU 159 154 154 GLU GLU M . n C 1 160 ARG 160 155 155 ARG ARG M . n C 1 161 GLN 161 156 156 GLN GLN M . n C 1 162 ASN 162 157 157 ASN ASN M . n C 1 163 GLY 163 158 158 GLY GLY M . n C 1 164 VAL 164 159 159 VAL VAL M . n C 1 165 LEU 165 160 160 LEU LEU M . n C 1 166 ASN 166 161 161 ASN ASN M . n C 1 167 SER 167 162 162 SER SER M . n C 1 168 TRP 168 163 163 TRP TRP M . n C 1 169 THR 169 164 164 THR THR M . n C 1 170 ASP 170 165 165 ASP ASP M . n C 1 171 GLN 171 166 166 GLN GLN M . n C 1 172 ASP 172 167 167 ASP ASP M . n C 1 173 SER 173 168 168 SER SER M . n C 1 174 LYS 174 169 169 LYS LYS M . n C 1 175 ASP 175 170 170 ASP ASP M . n C 1 176 SER 176 171 171 SER SER M . n C 1 177 THR 177 172 172 THR THR M . n C 1 178 TYR 178 173 173 TYR TYR M . n C 1 179 SER 179 174 174 SER SER M . n C 1 180 MET 180 175 175 MET MET M . n C 1 181 SER 181 176 176 SER SER M . n C 1 182 SER 182 177 177 SER SER M . n C 1 183 THR 183 178 178 THR THR M . n C 1 184 LEU 184 179 179 LEU LEU M . n C 1 185 THR 185 180 180 THR THR M . n C 1 186 LEU 186 181 181 LEU LEU M . n C 1 187 THR 187 182 182 THR THR M . n C 1 188 LYS 188 183 183 LYS LYS M . n C 1 189 ASP 189 184 184 ASP ASP M . n C 1 190 GLU 190 185 185 GLU GLU M . n C 1 191 TYR 191 186 186 TYR TYR M . n C 1 192 GLU 192 187 187 GLU GLU M . n C 1 193 ARG 193 188 188 ARG ARG M . n C 1 194 HIS 194 189 189 HIS HIS M . n C 1 195 ASN 195 190 190 ASN ASN M . n C 1 196 SER 196 191 191 SER SER M . n C 1 197 TYR 197 192 192 TYR TYR M . n C 1 198 THR 198 193 193 THR THR M . n C 1 199 CYS 199 194 194 CYS CYS M . n C 1 200 GLU 200 195 195 GLU GLU M . n C 1 201 ALA 201 196 196 ALA ALA M . n C 1 202 THR 202 197 197 THR THR M . n C 1 203 HIS 203 198 198 HIS HIS M . n C 1 204 LYS 204 199 199 LYS LYS M . n C 1 205 THR 205 200 200 THR THR M . n C 1 206 SER 206 201 201 SER SER M . n C 1 207 THR 207 202 202 THR THR M . n C 1 208 SER 208 203 203 SER SER M . n C 1 209 PRO 209 204 204 PRO PRO M . n C 1 210 ILE 210 205 205 ILE ILE M . n C 1 211 VAL 211 206 206 VAL VAL M . n C 1 212 LYS 212 207 207 LYS LYS M . n C 1 213 SER 213 208 208 SER SER M . n C 1 214 PHE 214 209 209 PHE PHE M . n C 1 215 ASN 215 210 210 ASN ASN M . n C 1 216 ARG 216 211 211 ARG ARG M . n C 1 217 ASN 217 212 212 ASN ASN M . n C 1 218 GLU 218 213 213 GLU GLU M . n C 1 219 CYS 219 214 214 CYS CYS M . n D 2 1 GLU 1 1 1 GLU GLU J . n D 2 2 VAL 2 2 2 VAL VAL J . n D 2 3 GLN 3 3 3 GLN GLN J . n D 2 4 LEU 4 4 4 LEU LEU J . n D 2 5 VAL 5 5 5 VAL VAL J . n D 2 6 GLU 6 6 6 GLU GLU J . n D 2 7 SER 7 7 7 SER SER J . n D 2 8 GLY 8 8 8 GLY GLY J . n D 2 9 GLY 9 9 9 GLY GLY J . n D 2 10 ASP 10 10 10 ASP ASP J . n D 2 11 LEU 11 11 11 LEU LEU J . n D 2 12 VAL 12 12 12 VAL VAL J . n D 2 13 LYS 13 13 13 LYS LYS J . n D 2 14 PRO 14 14 14 PRO PRO J . n D 2 15 GLY 15 15 15 GLY GLY J . n D 2 16 GLY 16 16 16 GLY GLY J . n D 2 17 SER 17 17 17 SER SER J . n D 2 18 LEU 18 18 18 LEU LEU J . n D 2 19 LYS 19 19 19 LYS LYS J . n D 2 20 LEU 20 20 20 LEU LEU J . n D 2 21 SER 21 21 21 SER SER J . n D 2 22 CYS 22 22 22 CYS CYS J . n D 2 23 ALA 23 23 23 ALA ALA J . n D 2 24 ALA 24 24 24 ALA ALA J . n D 2 25 SER 25 25 25 SER SER J . n D 2 26 GLY 26 26 26 GLY GLY J . n D 2 27 PHE 27 27 27 PHE PHE J . n D 2 28 THR 28 28 28 THR THR J . n D 2 29 PHE 29 29 29 PHE PHE J . n D 2 30 SER 30 30 30 SER SER J . n D 2 31 ARG 31 31 31 ARG ARG J . n D 2 32 CYS 32 32 32 CYS CYS J . n D 2 33 ALA 33 33 33 ALA ALA J . n D 2 34 MET 34 34 34 MET MET J . n D 2 35 SER 35 35 35 SER SER J . n D 2 36 TRP 36 36 36 TRP TRP J . n D 2 37 VAL 37 37 37 VAL VAL J . n D 2 38 ARG 38 38 38 ARG ARG J . n D 2 39 GLN 39 39 39 GLN GLN J . n D 2 40 THR 40 40 40 THR THR J . n D 2 41 PRO 41 41 41 PRO PRO J . n D 2 42 GLU 42 42 42 GLU GLU J . n D 2 43 LYS 43 43 43 LYS LYS J . n D 2 44 ARG 44 44 44 ARG ARG J . n D 2 45 LEU 45 45 45 LEU LEU J . n D 2 46 GLU 46 46 46 GLU GLU J . n D 2 47 TRP 47 47 47 TRP TRP J . n D 2 48 VAL 48 48 48 VAL VAL J . n D 2 49 ALA 49 49 49 ALA ALA J . n D 2 50 GLY 50 50 50 GLY GLY J . n D 2 51 ILE 51 51 51 ILE ILE J . n D 2 52 SER 52 52 52 SER SER J . n D 2 53 SER 53 52 52 SER SER J A n D 2 54 GLY 54 53 53 GLY GLY J . n D 2 55 GLY 55 54 54 GLY GLY J . n D 2 56 SER 56 55 55 SER SER J . n D 2 57 TYR 57 56 56 TYR TYR J . n D 2 58 THR 58 57 57 THR THR J . n D 2 59 PHE 59 58 58 PHE PHE J . n D 2 60 TYR 60 59 59 TYR TYR J . n D 2 61 PRO 61 60 60 PRO PRO J . n D 2 62 ASP 62 61 61 ASP ASP J . n D 2 63 THR 63 62 62 THR THR J . n D 2 64 VAL 64 63 63 VAL VAL J . n D 2 65 LYS 65 64 64 LYS LYS J . n D 2 66 GLY 66 65 65 GLY GLY J . n D 2 67 ARG 67 66 66 ARG ARG J . n D 2 68 PHE 68 67 67 PHE PHE J . n D 2 69 ILE 69 68 68 ILE ILE J . n D 2 70 ILE 70 69 69 ILE ILE J . n D 2 71 SER 71 70 70 SER SER J . n D 2 72 ARG 72 71 71 ARG ARG J . n D 2 73 ASN 73 72 72 ASN ASN J . n D 2 74 ASN 74 73 73 ASN ASN J . n D 2 75 ALA 75 74 74 ALA ALA J . n D 2 76 ARG 76 75 75 ARG ARG J . n D 2 77 ASN 77 76 76 ASN ASN J . n D 2 78 THR 78 77 77 THR THR J . n D 2 79 LEU 79 78 78 LEU LEU J . n D 2 80 SER 80 79 79 SER SER J . n D 2 81 LEU 81 80 80 LEU LEU J . n D 2 82 GLN 82 81 81 GLN GLN J . n D 2 83 MET 83 82 82 MET MET J . n D 2 84 SER 84 82 82 SER SER J A n D 2 85 SER 85 82 82 SER SER J B n D 2 86 LEU 86 82 82 LEU LEU J C n D 2 87 ARG 87 83 83 ARG ARG J . n D 2 88 SER 88 84 84 SER SER J . n D 2 89 GLU 89 85 85 GLU GLU J . n D 2 90 ASP 90 86 86 ASP ASP J . n D 2 91 THR 91 87 87 THR THR J . n D 2 92 ALA 92 88 88 ALA ALA J . n D 2 93 ILE 93 89 89 ILE ILE J . n D 2 94 TYR 94 90 90 TYR TYR J . n D 2 95 TYR 95 91 91 TYR TYR J . n D 2 96 CYS 96 92 92 CYS CYS J . n D 2 97 THR 97 93 93 THR THR J . n D 2 98 ARG 98 94 94 ARG ARG J . n D 2 99 TYR 99 95 95 TYR TYR J . n D 2 100 SER 100 96 96 SER SER J . n D 2 101 SER 101 97 97 SER SER J . n D 2 102 ASP 102 98 98 ASP ASP J . n D 2 103 PRO 103 99 99 PRO PRO J . n D 2 104 PHE 104 100 100 PHE PHE J . n D 2 105 TYR 105 100 100 TYR TYR J B n D 2 106 PHE 106 100 100 PHE PHE J C n D 2 107 ASP 107 101 101 ASP ASP J . n D 2 108 TYR 108 102 102 TYR TYR J . n D 2 109 TRP 109 103 103 TRP TRP J . n D 2 110 GLY 110 104 104 GLY GLY J . n D 2 111 GLN 111 105 105 GLN GLN J . n D 2 112 GLY 112 106 106 GLY GLY J . n D 2 113 THR 113 107 107 THR THR J . n D 2 114 THR 114 108 108 THR THR J . n D 2 115 LEU 115 109 109 LEU LEU J . n D 2 116 THR 116 110 110 THR THR J . n D 2 117 VAL 117 111 111 VAL VAL J . n D 2 118 SER 118 112 112 SER SER J . n D 2 119 SER 119 113 113 SER SER J . n D 2 120 ALA 120 114 114 ALA ALA J . n D 2 121 LYS 121 115 115 LYS LYS J . n D 2 122 THR 122 116 116 THR THR J . n D 2 123 THR 123 117 117 THR THR J . n D 2 124 PRO 124 118 118 PRO PRO J . n D 2 125 PRO 125 119 119 PRO PRO J . n D 2 126 SER 126 120 120 SER SER J . n D 2 127 VAL 127 121 121 VAL VAL J . n D 2 128 TYR 128 122 122 TYR TYR J . n D 2 129 PRO 129 123 123 PRO PRO J . n D 2 130 LEU 130 124 124 LEU LEU J . n D 2 131 ALA 131 125 125 ALA ALA J . n D 2 132 PRO 132 126 126 PRO PRO J . n D 2 133 GLY 133 127 127 GLY GLY J . n D 2 134 SER 134 128 128 SER SER J . n D 2 135 ALA 135 129 129 ALA ALA J . n D 2 136 ALA 136 130 130 ALA ALA J . n D 2 137 GLN 137 133 133 GLN GLN J . n D 2 138 THR 138 134 134 THR THR J . n D 2 139 ASN 139 135 135 ASN ASN J . n D 2 140 SER 140 136 136 SER SER J . n D 2 141 MET 141 137 137 MET MET J . n D 2 142 VAL 142 138 138 VAL VAL J . n D 2 143 THR 143 139 139 THR THR J . n D 2 144 LEU 144 140 140 LEU LEU J . n D 2 145 GLY 145 141 141 GLY GLY J . n D 2 146 CYS 146 142 142 CYS CYS J . n D 2 147 LEU 147 143 143 LEU LEU J . n D 2 148 VAL 148 144 144 VAL VAL J . n D 2 149 LYS 149 145 145 LYS LYS J . n D 2 150 GLY 150 146 146 GLY GLY J . n D 2 151 TYR 151 147 147 TYR TYR J . n D 2 152 PHE 152 148 148 PHE PHE J . n D 2 153 PRO 153 149 149 PRO PRO J . n D 2 154 GLU 154 150 150 GLU GLU J . n D 2 155 PRO 155 151 151 PRO PRO J . n D 2 156 VAL 156 152 152 VAL VAL J . n D 2 157 THR 157 153 153 THR THR J . n D 2 158 VAL 158 154 154 VAL VAL J . n D 2 159 THR 159 156 156 THR THR J . n D 2 160 TRP 160 157 157 TRP TRP J . n D 2 161 ASN 161 162 162 ASN ASN J . n D 2 162 SER 162 163 163 SER SER J . n D 2 163 GLY 163 164 164 GLY GLY J . n D 2 164 SER 164 165 165 SER SER J . n D 2 165 LEU 165 166 166 LEU LEU J . n D 2 166 SER 166 167 167 SER SER J . n D 2 167 SER 167 168 168 SER SER J . n D 2 168 GLY 168 169 169 GLY GLY J . n D 2 169 VAL 169 171 171 VAL VAL J . n D 2 170 HIS 170 172 172 HIS HIS J . n D 2 171 THR 171 173 173 THR THR J . n D 2 172 PHE 172 174 174 PHE PHE J . n D 2 173 PRO 173 175 175 PRO PRO J . n D 2 174 ALA 174 176 176 ALA ALA J . n D 2 175 VAL 175 177 177 VAL VAL J . n D 2 176 LEU 176 178 178 LEU LEU J . n D 2 177 GLN 177 179 179 GLN GLN J . n D 2 178 SER 178 180 180 SER SER J . n D 2 179 ASP 179 183 183 ASP ASP J . n D 2 180 LEU 180 184 184 LEU LEU J . n D 2 181 TYR 181 185 185 TYR TYR J . n D 2 182 THR 182 186 186 THR THR J . n D 2 183 LEU 183 187 187 LEU LEU J . n D 2 184 SER 184 188 188 SER SER J . n D 2 185 SER 185 189 189 SER SER J . n D 2 186 SER 186 190 190 SER SER J . n D 2 187 VAL 187 191 191 VAL VAL J . n D 2 188 THR 188 192 192 THR THR J . n D 2 189 VAL 189 193 193 VAL VAL J . n D 2 190 PRO 190 194 194 PRO PRO J . n D 2 191 SER 191 195 195 SER SER J . n D 2 192 SER 192 196 196 SER SER J . n D 2 193 PRO 193 198 198 PRO PRO J . n D 2 194 ARG 194 199 199 ARG ARG J . n D 2 195 PRO 195 200 200 PRO PRO J . n D 2 196 SER 196 202 202 SER SER J . n D 2 197 GLU 197 203 203 GLU GLU J . n D 2 198 THR 198 204 204 THR THR J . n D 2 199 VAL 199 205 205 VAL VAL J . n D 2 200 THR 200 206 206 THR THR J . n D 2 201 CYS 201 208 208 CYS CYS J . n D 2 202 ASN 202 209 209 ASN ASN J . n D 2 203 VAL 203 210 210 VAL VAL J . n D 2 204 ALA 204 211 211 ALA ALA J . n D 2 205 HIS 205 212 212 HIS HIS J . n D 2 206 PRO 206 213 213 PRO PRO J . n D 2 207 ALA 207 214 214 ALA ALA J . n D 2 208 SER 208 215 215 SER SER J . n D 2 209 SER 209 216 216 SER SER J . n D 2 210 THR 210 217 217 THR THR J . n D 2 211 LYS 211 218 218 LYS LYS J . n D 2 212 VAL 212 219 219 VAL VAL J . n D 2 213 ASP 213 220 220 ASP ASP J . n D 2 214 LYS 214 221 221 LYS LYS J . n D 2 215 LYS 215 222 222 LYS LYS J . n D 2 216 ILE 216 223 223 ILE ILE J . n D 2 217 VAL 217 226 226 VAL VAL J . n D 2 218 PRO 218 227 227 PRO PRO J . n D 2 219 ARG 219 228 ? ? ? J . n D 2 220 ASP 220 229 ? ? ? J . n D 2 221 CYS 221 230 ? ? ? J . n # _pdbx_nonpoly_scheme.asym_id E _pdbx_nonpoly_scheme.entity_id 3 _pdbx_nonpoly_scheme.mon_id NAG _pdbx_nonpoly_scheme.ndb_seq_num 1 _pdbx_nonpoly_scheme.pdb_seq_num 901 _pdbx_nonpoly_scheme.auth_seq_num 901 _pdbx_nonpoly_scheme.pdb_mon_id NAG _pdbx_nonpoly_scheme.auth_mon_id NAG _pdbx_nonpoly_scheme.pdb_strand_id L _pdbx_nonpoly_scheme.pdb_ins_code . # _pdbx_struct_mod_residue.id 1 _pdbx_struct_mod_residue.label_asym_id A _pdbx_struct_mod_residue.label_comp_id ASN _pdbx_struct_mod_residue.label_seq_id 26 _pdbx_struct_mod_residue.auth_asym_id L _pdbx_struct_mod_residue.auth_comp_id ASN _pdbx_struct_mod_residue.auth_seq_id 26 _pdbx_struct_mod_residue.PDB_ins_code ? _pdbx_struct_mod_residue.parent_comp_id ASN _pdbx_struct_mod_residue.details 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details tetrameric _pdbx_struct_assembly.oligomeric_count 4 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 1992-04-15 2 'Structure model' 1 1 2008-03-24 3 'Structure model' 1 2 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Non-polymer description' 3 3 'Structure model' 'Version format compliance' # _software.name X-PLOR _software.classification refinement _software.version . _software.citation_id ? _software.pdbx_ordinal 1 # _pdbx_entry_details.entry_id 1IGF _pdbx_entry_details.compound_details ? _pdbx_entry_details.source_details ? _pdbx_entry_details.nonpolymer_details ;NAG N 901 IS LINKED TO ASN L 26 OF THE FIRST FAB' FRAGMENT IN THE ASYMMETRIC UNIT. BECAUSE DENSITY FOR THE CORRESPONDING NAG ON THE SECOND FAB' FRAGMENT IS WEAK, THES NAG COORDINATES ARE NOT INCLUDED. ; _pdbx_entry_details.sequence_details ;THE FAB' FRAGMENT IS NUMBERED BY THE CONVENTION OF E.KABAT (E.A.KABAT,T.T.WU,M.REID-MILLER,H.M.PERRY,K.S.GOTTESMAN, SEQUENCES OF PROTEINS OF IMMUNOLOGICAL INTEREST, 4TH ED., (1987), NATIONAL INSTITUTE OF HEALTH,BETHESDA,MD.). ; # loop_ _pdbx_validate_rmsd_bond.id _pdbx_validate_rmsd_bond.PDB_model_num _pdbx_validate_rmsd_bond.auth_atom_id_1 _pdbx_validate_rmsd_bond.auth_asym_id_1 _pdbx_validate_rmsd_bond.auth_comp_id_1 _pdbx_validate_rmsd_bond.auth_seq_id_1 _pdbx_validate_rmsd_bond.PDB_ins_code_1 _pdbx_validate_rmsd_bond.label_alt_id_1 _pdbx_validate_rmsd_bond.auth_atom_id_2 _pdbx_validate_rmsd_bond.auth_asym_id_2 _pdbx_validate_rmsd_bond.auth_comp_id_2 _pdbx_validate_rmsd_bond.auth_seq_id_2 _pdbx_validate_rmsd_bond.PDB_ins_code_2 _pdbx_validate_rmsd_bond.label_alt_id_2 _pdbx_validate_rmsd_bond.bond_value _pdbx_validate_rmsd_bond.bond_target_value _pdbx_validate_rmsd_bond.bond_deviation _pdbx_validate_rmsd_bond.bond_standard_deviation _pdbx_validate_rmsd_bond.linker_flag 1 1 NE2 L HIS 93 ? ? CD2 L HIS 93 ? ? 1.307 1.373 -0.066 0.011 N 2 1 NE2 L HIS 189 ? ? CD2 L HIS 189 ? ? 1.300 1.373 -0.073 0.011 N 3 1 NE2 L HIS 198 ? ? CD2 L HIS 198 ? ? 1.302 1.373 -0.071 0.011 N 4 1 NE2 H HIS 172 ? ? CD2 H HIS 172 ? ? 1.306 1.373 -0.067 0.011 N 5 1 NE2 H HIS 212 ? ? CD2 H HIS 212 ? ? 1.295 1.373 -0.078 0.011 N 6 1 NE2 M HIS 93 ? ? CD2 M HIS 93 ? ? 1.305 1.373 -0.068 0.011 N 7 1 NE2 M HIS 189 ? ? CD2 M HIS 189 ? ? 1.300 1.373 -0.073 0.011 N 8 1 NE2 M HIS 198 ? ? CD2 M HIS 198 ? ? 1.298 1.373 -0.075 0.011 N 9 1 NE2 J HIS 172 ? ? CD2 J HIS 172 ? ? 1.302 1.373 -0.071 0.011 N 10 1 NE2 J HIS 212 ? ? CD2 J HIS 212 ? ? 1.306 1.373 -0.067 0.011 N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CA L LEU 3 ? ? CB L LEU 3 ? ? CG L LEU 3 ? ? 130.11 115.30 14.81 2.30 N 2 1 CA L LEU 9 ? ? CB L LEU 9 ? ? CG L LEU 9 ? ? 131.44 115.30 16.14 2.30 N 3 1 CA L CYS 23 ? ? CB L CYS 23 ? ? SG L CYS 23 ? ? 120.80 114.20 6.60 1.10 N 4 1 CD1 L TRP 35 ? ? CG L TRP 35 ? ? CD2 L TRP 35 ? ? 112.00 106.30 5.70 0.80 N 5 1 CE2 L TRP 35 ? ? CD2 L TRP 35 ? ? CG L TRP 35 ? ? 101.85 107.30 -5.45 0.80 N 6 1 CA L LEU 83 ? ? CB L LEU 83 ? ? CG L LEU 83 ? ? 131.49 115.30 16.19 2.30 N 7 1 CA L LEU 104 ? ? CB L LEU 104 ? ? CG L LEU 104 ? ? 134.52 115.30 19.22 2.30 N 8 1 NE L ARG 108 ? ? CZ L ARG 108 ? ? NH1 L ARG 108 ? ? 124.19 120.30 3.89 0.50 N 9 1 CD1 L TRP 148 ? ? CG L TRP 148 ? ? CD2 L TRP 148 ? ? 113.13 106.30 6.83 0.80 N 10 1 CE2 L TRP 148 ? ? CD2 L TRP 148 ? ? CG L TRP 148 ? ? 101.42 107.30 -5.88 0.80 N 11 1 N L ARG 155 ? ? CA L ARG 155 ? ? C L ARG 155 ? ? 90.58 111.00 -20.42 2.70 N 12 1 CA L ASN 157 ? ? CB L ASN 157 ? ? CG L ASN 157 ? ? 97.27 113.40 -16.13 2.20 N 13 1 CG1 L VAL 159 ? ? CB L VAL 159 ? ? CG2 L VAL 159 ? ? 100.88 110.90 -10.02 1.60 N 14 1 CD1 L TRP 163 ? ? CG L TRP 163 ? ? CD2 L TRP 163 ? ? 112.23 106.30 5.93 0.80 N 15 1 CE2 L TRP 163 ? ? CD2 L TRP 163 ? ? CG L TRP 163 ? ? 102.04 107.30 -5.26 0.80 N 16 1 CG L MET 175 ? ? SD L MET 175 ? ? CE L MET 175 ? ? 88.95 100.20 -11.25 1.60 N 17 1 NE L ARG 188 ? ? CZ L ARG 188 ? ? NH2 L ARG 188 ? ? 114.89 120.30 -5.41 0.50 N 18 1 CB L TYR 192 ? ? CG L TYR 192 ? ? CD2 L TYR 192 ? ? 116.47 121.00 -4.53 0.60 N 19 1 CG H MET 34 ? ? SD H MET 34 ? ? CE H MET 34 ? ? 85.06 100.20 -15.14 1.60 N 20 1 CD1 H TRP 36 ? ? CG H TRP 36 ? ? CD2 H TRP 36 ? ? 112.86 106.30 6.56 0.80 N 21 1 CE2 H TRP 36 ? ? CD2 H TRP 36 ? ? CG H TRP 36 ? ? 101.58 107.30 -5.72 0.80 N 22 1 NE H ARG 38 ? ? CZ H ARG 38 ? ? NH1 H ARG 38 ? ? 124.41 120.30 4.11 0.50 N 23 1 CD1 H TRP 47 ? ? CG H TRP 47 ? ? CD2 H TRP 47 ? ? 111.95 106.30 5.65 0.80 N 24 1 CE2 H TRP 47 ? ? CD2 H TRP 47 ? ? CG H TRP 47 ? ? 102.05 107.30 -5.25 0.80 N 25 1 CB H TYR 56 ? ? CG H TYR 56 ? ? CD2 H TYR 56 ? ? 116.56 121.00 -4.44 0.60 N 26 1 NE H ARG 75 ? ? CZ H ARG 75 ? ? NH1 H ARG 75 ? ? 123.63 120.30 3.33 0.50 N 27 1 CG H MET 82 ? ? SD H MET 82 ? ? CE H MET 82 ? ? 84.91 100.20 -15.29 1.60 N 28 1 NE H ARG 94 ? ? CZ H ARG 94 ? ? NH1 H ARG 94 ? ? 125.67 120.30 5.37 0.50 N 29 1 NE H ARG 94 ? ? CZ H ARG 94 ? ? NH2 H ARG 94 ? ? 117.21 120.30 -3.09 0.50 N 30 1 CB H TYR 95 ? ? CG H TYR 95 ? ? CD1 H TYR 95 ? ? 116.56 121.00 -4.44 0.60 N 31 1 CD1 H TRP 103 ? ? CG H TRP 103 ? ? CD2 H TRP 103 ? ? 112.14 106.30 5.84 0.80 N 32 1 CE2 H TRP 103 ? ? CD2 H TRP 103 ? ? CG H TRP 103 ? ? 102.23 107.30 -5.07 0.80 N 33 1 CA H MET 137 ? ? CB H MET 137 ? ? CG H MET 137 ? ? 102.39 113.30 -10.91 1.70 N 34 1 CG H MET 137 ? ? SD H MET 137 ? ? CE H MET 137 ? ? 83.65 100.20 -16.55 1.60 N 35 1 CD1 H TRP 157 ? ? CG H TRP 157 ? ? CD2 H TRP 157 ? ? 112.89 106.30 6.59 0.80 N 36 1 CE2 H TRP 157 ? ? CD2 H TRP 157 ? ? CG H TRP 157 ? ? 101.93 107.30 -5.37 0.80 N 37 1 CA H THR 192 ? ? CB H THR 192 ? ? OG1 H THR 192 ? ? 95.57 109.00 -13.43 2.10 N 38 1 CA H THR 192 ? ? CB H THR 192 ? ? CG2 H THR 192 ? ? 121.67 112.40 9.27 1.40 N 39 1 NE H ARG 199 ? ? CZ H ARG 199 ? ? NH1 H ARG 199 ? ? 126.72 120.30 6.42 0.50 N 40 1 CG M MET 4 ? ? SD M MET 4 ? ? CE M MET 4 ? ? 84.05 100.20 -16.15 1.60 N 41 1 N M THR 31 ? ? CA M THR 31 ? ? C M THR 31 ? ? 127.28 111.00 16.28 2.70 N 42 1 CB M TYR 32 ? ? CG M TYR 32 ? ? CD2 M TYR 32 ? ? 116.39 121.00 -4.61 0.60 N 43 1 CD1 M TRP 35 ? ? CG M TRP 35 ? ? CD2 M TRP 35 ? ? 113.49 106.30 7.19 0.80 N 44 1 CE2 M TRP 35 ? ? CD2 M TRP 35 ? ? CG M TRP 35 ? ? 101.31 107.30 -5.99 0.80 N 45 1 NE M ARG 61 ? ? CZ M ARG 61 ? ? NH1 M ARG 61 ? ? 124.03 120.30 3.73 0.50 N 46 1 N M ARG 77 ? ? CA M ARG 77 ? ? C M ARG 77 ? ? 94.70 111.00 -16.30 2.70 N 47 1 CA M GLN 90 ? ? CB M GLN 90 ? ? CG M GLN 90 ? ? 127.54 113.40 14.14 2.20 N 48 1 CD1 M TRP 148 ? ? CG M TRP 148 ? ? CD2 M TRP 148 ? ? 112.28 106.30 5.98 0.80 N 49 1 CE2 M TRP 148 ? ? CD2 M TRP 148 ? ? CG M TRP 148 ? ? 101.73 107.30 -5.57 0.80 N 50 1 CD1 M TRP 163 ? ? CG M TRP 163 ? ? CD2 M TRP 163 ? ? 113.13 106.30 6.83 0.80 N 51 1 CE2 M TRP 163 ? ? CD2 M TRP 163 ? ? CG M TRP 163 ? ? 101.24 107.30 -6.06 0.80 N 52 1 NE M ARG 188 ? ? CZ M ARG 188 ? ? NH1 M ARG 188 ? ? 124.87 120.30 4.57 0.50 N 53 1 NE M ARG 211 ? ? CZ M ARG 211 ? ? NH2 M ARG 211 ? ? 116.44 120.30 -3.86 0.50 N 54 1 CA M CYS 214 ? ? CB M CYS 214 ? ? SG M CYS 214 ? ? 120.83 114.20 6.63 1.10 N 55 1 CB J LEU 20 ? ? CG J LEU 20 ? ? CD2 J LEU 20 ? ? 99.52 111.00 -11.48 1.70 N 56 1 NE J ARG 31 ? ? CZ J ARG 31 ? ? NH1 J ARG 31 ? ? 123.83 120.30 3.53 0.50 N 57 1 NE J ARG 31 ? ? CZ J ARG 31 ? ? NH2 J ARG 31 ? ? 117.12 120.30 -3.18 0.50 N 58 1 CG J MET 34 ? ? SD J MET 34 ? ? CE J MET 34 ? ? 90.26 100.20 -9.94 1.60 N 59 1 CD1 J TRP 36 ? ? CG J TRP 36 ? ? CD2 J TRP 36 ? ? 111.76 106.30 5.46 0.80 N 60 1 CB J TRP 36 ? ? CG J TRP 36 ? ? CD1 J TRP 36 ? ? 118.67 127.00 -8.33 1.30 N 61 1 CE2 J TRP 36 ? ? CD2 J TRP 36 ? ? CG J TRP 36 ? ? 101.84 107.30 -5.46 0.80 N 62 1 CG J TRP 36 ? ? CD2 J TRP 36 ? ? CE3 J TRP 36 ? ? 140.38 133.90 6.48 0.90 N 63 1 CD1 J TRP 47 ? ? CG J TRP 47 ? ? CD2 J TRP 47 ? ? 113.37 106.30 7.07 0.80 N 64 1 CG J TRP 47 ? ? CD1 J TRP 47 ? ? NE1 J TRP 47 ? ? 104.06 110.10 -6.04 1.00 N 65 1 CE2 J TRP 47 ? ? CD2 J TRP 47 ? ? CG J TRP 47 ? ? 101.39 107.30 -5.91 0.80 N 66 1 NE J ARG 66 ? ? CZ J ARG 66 ? ? NH2 J ARG 66 ? ? 115.09 120.30 -5.21 0.50 N 67 1 CB J PHE 67 ? ? CG J PHE 67 ? ? CD2 J PHE 67 ? ? 116.53 120.80 -4.27 0.70 N 68 1 CB J TYR 91 ? ? CG J TYR 91 ? ? CD2 J TYR 91 ? ? 116.88 121.00 -4.12 0.60 N 69 1 NE J ARG 94 ? ? CZ J ARG 94 ? ? NH2 J ARG 94 ? ? 116.38 120.30 -3.92 0.50 N 70 1 CD1 J TRP 103 ? ? CG J TRP 103 ? ? CD2 J TRP 103 ? ? 112.63 106.30 6.33 0.80 N 71 1 CE2 J TRP 103 ? ? CD2 J TRP 103 ? ? CG J TRP 103 ? ? 101.71 107.30 -5.59 0.80 N 72 1 CB J TYR 122 ? ? CG J TYR 122 ? ? CD2 J TYR 122 ? ? 116.96 121.00 -4.04 0.60 N 73 1 CD1 J TRP 157 ? ? CG J TRP 157 ? ? CD2 J TRP 157 ? ? 113.64 106.30 7.34 0.80 N 74 1 CE2 J TRP 157 ? ? CD2 J TRP 157 ? ? CG J TRP 157 ? ? 101.33 107.30 -5.97 0.80 N 75 1 CA J LEU 187 ? ? CB J LEU 187 ? ? CG J LEU 187 ? ? 135.62 115.30 20.32 2.30 N 76 1 NE J ARG 199 ? ? CZ J ARG 199 ? ? NH1 J ARG 199 ? ? 125.04 120.30 4.74 0.50 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP L 30 ? ? -175.49 -177.06 2 1 VAL L 51 ? ? 54.19 -36.60 3 1 ARG L 61 ? ? 167.71 -45.81 4 1 SER L 65 ? ? 177.40 170.94 5 1 GLU L 81 ? ? -104.41 49.50 6 1 ASN L 138 ? ? 59.86 72.46 7 1 SER L 153 ? ? -91.08 -62.60 8 1 ASP L 170 ? ? -157.99 21.21 9 1 ASN L 190 ? ? -129.20 -54.63 10 1 LYS L 199 ? ? -22.42 -44.95 11 1 PRO L 204 ? ? -47.39 150.78 12 1 ARG L 211 ? ? -93.42 58.76 13 1 ASN L 212 ? ? 168.98 -6.96 14 1 PRO H 14 ? ? -53.04 5.80 15 1 PRO H 41 ? ? -2.23 -86.80 16 1 LYS H 43 ? ? 41.91 19.62 17 1 ASN H 72 ? ? -69.93 22.94 18 1 ASN H 73 ? ? 5.52 -33.14 19 1 ALA H 88 ? ? 179.63 -176.06 20 1 PRO H 99 ? ? -65.87 52.21 21 1 SER H 128 ? ? 57.28 -173.93 22 1 ALA H 130 ? ? 71.28 178.74 23 1 GLN H 133 ? ? -100.65 -134.68 24 1 ASN H 135 ? ? 178.85 154.84 25 1 SER H 136 ? ? 52.22 -81.31 26 1 SER H 163 ? ? 52.48 4.76 27 1 SER H 168 ? ? -61.80 -75.64 28 1 GLN H 179 ? ? -87.58 -103.49 29 1 ASP H 183 ? ? 47.37 28.11 30 1 PRO H 198 ? ? -63.32 -74.51 31 1 PRO H 200 ? ? -49.34 -70.83 32 1 ALA H 214 ? ? -60.91 22.52 33 1 SER H 215 ? ? -161.52 12.42 34 1 SER H 216 ? ? 49.73 23.93 35 1 LEU M 11 ? ? -154.95 89.69 36 1 ASP M 30 ? ? -52.34 86.87 37 1 THR M 31 ? ? 67.39 118.40 38 1 VAL M 51 ? ? 65.16 -49.56 39 1 SER M 52 ? ? -156.46 71.62 40 1 ARG M 61 ? ? -59.99 -9.18 41 1 GLU M 81 ? ? -62.90 10.00 42 1 SER M 92 ? ? -69.77 14.05 43 1 ASN M 138 ? ? 51.00 74.31 44 1 PRO M 141 ? ? -64.61 -168.36 45 1 ASP M 151 ? ? 45.79 75.85 46 1 SER M 153 ? ? -79.06 40.16 47 1 SER M 168 ? ? -37.16 -78.51 48 1 ASP M 170 ? ? 145.76 -31.96 49 1 ASN M 190 ? ? -145.92 -18.08 50 1 LYS M 199 ? ? -45.76 -12.24 51 1 ARG M 211 ? ? -51.37 -1.74 52 1 ARG J 31 ? ? -177.32 -25.19 53 1 GLU J 42 ? ? -91.14 30.94 54 1 ALA J 49 ? ? 174.67 158.19 55 1 SER J 52 A ? -10.84 -39.37 56 1 ASN J 72 ? ? -161.25 103.31 57 1 ASN J 76 ? ? 65.96 85.10 58 1 SER J 128 ? ? 50.52 -150.92 59 1 ALA J 130 ? ? 53.59 -113.91 60 1 GLN J 133 ? ? 61.63 99.38 61 1 ASN J 135 ? ? -94.98 -65.03 62 1 SER J 136 ? ? -178.83 -32.19 63 1 LEU J 166 ? ? -161.36 91.88 64 1 SER J 168 ? ? -54.61 -91.36 65 1 GLN J 179 ? ? -108.78 -114.68 66 1 ASP J 183 ? ? 53.96 13.28 67 1 ALA J 214 ? ? -38.34 -29.97 68 1 SER J 216 ? ? -58.00 85.65 # loop_ _pdbx_validate_peptide_omega.id _pdbx_validate_peptide_omega.PDB_model_num _pdbx_validate_peptide_omega.auth_comp_id_1 _pdbx_validate_peptide_omega.auth_asym_id_1 _pdbx_validate_peptide_omega.auth_seq_id_1 _pdbx_validate_peptide_omega.PDB_ins_code_1 _pdbx_validate_peptide_omega.label_alt_id_1 _pdbx_validate_peptide_omega.auth_comp_id_2 _pdbx_validate_peptide_omega.auth_asym_id_2 _pdbx_validate_peptide_omega.auth_seq_id_2 _pdbx_validate_peptide_omega.PDB_ins_code_2 _pdbx_validate_peptide_omega.label_alt_id_2 _pdbx_validate_peptide_omega.omega 1 1 THR H 40 ? ? PRO H 41 ? ? 140.04 2 1 VAL M 94 ? ? PRO M 95 ? ? -35.18 # _pdbx_validate_main_chain_plane.id 1 _pdbx_validate_main_chain_plane.PDB_model_num 1 _pdbx_validate_main_chain_plane.auth_comp_id GLU _pdbx_validate_main_chain_plane.auth_asym_id L _pdbx_validate_main_chain_plane.auth_seq_id 154 _pdbx_validate_main_chain_plane.PDB_ins_code ? _pdbx_validate_main_chain_plane.label_alt_id ? _pdbx_validate_main_chain_plane.improper_torsion_angle 11.35 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 H ARG 228 ? B ARG 219 2 1 Y 1 H ASP 229 ? B ASP 220 3 1 Y 1 H CYS 230 ? B CYS 221 4 1 Y 1 J ARG 228 ? D ARG 219 5 1 Y 1 J ASP 229 ? D ASP 220 6 1 Y 1 J CYS 230 ? D CYS 221 # _pdbx_entity_nonpoly.entity_id 3 _pdbx_entity_nonpoly.name N-ACETYL-D-GLUCOSAMINE _pdbx_entity_nonpoly.comp_id NAG #