==== Front Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igaa057.3027 igaa057.3027 Abstracts Session 7590 (Symposium) AcademicSubjects/SOC02600 Innovative Approaches to Understanding Resilience Windham B Gwen Chair Griswold Michael Co-Chair 2020 16 12 2020 16 12 2020 4 Suppl 1 Program Abstracts from The GSA 2020 Annual Scientific Meeting “Turning 75: Why Age Matters”828 828 © The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America.2020This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.Abstract Physical resilience, generally defined as the ability to recover or resist functional decline following a stressor, holds promise for clinicians to identify patients who are likely to benefit from a planned stressor (such as an elective procedure) or deteriorate after an unplanned stressor (such as heart failure). This symposium will present innovative research approaches that enhance understanding of the constructs of resilience from human and animal models. The symposium will include presentations from leading experts addressing issues in the study of resilience including choices of definitions, study design, comparator groups, and considerations of underlying latent factors. Data from population-based cohort studies and animal models will be presented to inform the discussions. This interdisciplinary symposium will address recommendations for advancing resilience knowledge through elucidating biologic, clinical and environmental influences and optimizing definitions, designs, and analyses. Epidemiology of Aging Interest Group Sponsored Symposium.