==== Front Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igaa057.2014 igaa057.2014 Abstracts Session 5625 (Symposium) AcademicSubjects/SOC02600 Evaluating Daily Versus Global Stress Appraisals’ Sensitivity to Mild Cognitive Impairment Cerino Eric 1 Scott Stacey 2 Zhaoyang Ruixue 3 Lipton Richard 4 Sliwinski Martin 5 1 Pennsylvania State University, University Park, Pennsylvania, United States 2 Stony Brook University, Stony Brook, New York, United States 3 The Pennsylvania State University, University Park, Pennsylvania, United States 4 Albert Einstein College of Medicine, Bronx, New York, United States 5 Penn State University, University Park, Pennsylvania, United States 2020 16 12 2020 16 12 2020 4 Suppl 1 Program Abstracts from The GSA 2020 Annual Scientific Meeting “Turning 75: Why Age Matters”598 599 © The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America.2020This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.Abstract Stress is an important correlate of cognitive aging that manifests in everyday life. Infrequent trait-based stress measures may not be as sensitive to mild cognitive impairment (MCI) as ecological momentary assessments (EMA). We compared EMA to global trait-based stress measures in discriminating MCI. A sample of 248 adults from the Einstein Aging Study (Mage=77.33 years, SD=5.04; 68 with MCI) were prompted to report whether a stressor occurred and to rate the severity up to four times daily for 14 days. Global perceived stress and neuroticism were assessed at baseline. Although MCI status was unrelated to stressor frequency (p>.05), individuals with MCI appraised their daily stressors as more severe than cognitively intact participants (p=.03). No MCI-related differences emerged on global stress or neuroticism assessments (ps>.05). Results suggest everyday stress markers may be more sensitive to differentiating MCI than global assessments and point toward their utility for early identification of pathological declines.