==== Front Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igaa057.1277 igaa057.1277 Abstracts Session 2953 (Poster) Social Determinants of Health AcademicSubjects/SOC02600 Opioid Literacy in an Immigrant Group in Rural Area: Use of Social Determinant of Health Framework Lee Hee Yun 1 Choi Eun Young 2 Song Jieun 3 Gajos Jamie 4 Luo Yan 1 1 University of Alabama, Tuscaloosa, Alabama, United States 2 Leonard Davis School of Gerontology, Los Angeles, California, United States 3 Waisman center, Madison, Wisconsin, United States 4 The University of Alabama, Tuscaloosa, Alabama, United States 2020 16 12 2020 16 12 2020 4 Suppl 1 Program Abstracts from The GSA 2020 Annual Scientific Meeting “Turning 75: Why Age Matters”397 397 © The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America.2020This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.Abstract Opioid overdose risk is particularly high in immigrant communities partly due to limited English proficiency (Guarino et al., 2015). Previous studies reported that social determinants of health (SDH) have been associated with risk for opioid overdose (Dasgupta et al., 2018). The current study examines the association between SDH and literacy of opioid overdose risk among the immigrant population living in a rural area. Specifically, we examine the association in various age groups including young adults (aged 20 to 34), middle-aged (aged 35 to 49), and older adults (ages 50 to 75). Data were drawn from a sample of Korean American immigrants residing in rural Alabama (N=225). The participants administered the Brief Opioid Knowledge (BOOK) Questionnaire (Dunn et al., 2016). Multiple regression analyses were conducted for three age groups to identify predictors of opioid literacy. Overall, older adults had lower levels of opioid literacy relative to their younger counterparts. Among young adults, low English proficiency, more chronic conditions, and greater depressive symptoms were significant predictors of limited opioid literacy. For the middle-aged adults, lower levels of health literacy and more pain symptoms were associated with limited opioid literacy. Among older adults, women, those with higher English proficiency, and lower health literacy had lower levels of opioid literacy. The findings demonstrated a greater vulnerability of older immigrants to limited opioid literacy. Different predictors based on SDH of limited opioid literacy across age groups have implications for tailored health promotion strategies to reduce opioid overdose risk.