==== Front Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igaa057.2626 igaa057.2626 Abstracts Session 6510 (Symposium) AcademicSubjects/SOC02600 Cognitive Aging: New Insights Into How Our Brains Age Murphy Coleen Chair Villeda Saul Discussant 2020 16 12 2020 16 12 2020 4 Suppl 1 Program Abstracts from The GSA 2020 Annual Scientific Meeting “Turning 75: Why Age Matters”738 738 © The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America.2020This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.Abstract Maintaining quality of life with age is as important as slowing human aging. Slowing cognitive decline will be a critical aspect of keeping older adults healthy as we extend lifespan. To that end, identifying the molecular regulators of neuronal health, including learning and memory, in model systems that can later be applied to humans is an important step. In this symposium, we will hear about work on cognitive decline and its prevention being done in a variety of model systems.