==== Front Innov Aging Innov Aging innovateage Innovation in Aging 2399-5300 Oxford University Press US 10.1093/geroni/igaa057.2239 igaa057.2239 Abstracts Session 5890 (Symposium) AcademicSubjects/SOC02600 Overview of REJOIN: A Clinical Trial to Use Exercise to Relieve Joint Pain in Older Breast Cancer Survivors Bluethmann Shirley 1 Truica Cristina 2 Olsen Nancy 1 Sciamanna Christopher 1 Klepin Heidi 3 Chinchilli Vernon 1 Schmitz Kathryn 1 1 Penn State College of Medicine, Hershey, Pennsylvania, United States 2 Penn State Cancer Institute, Hershey, Pennsylvania, United States 3 Wake Forest School of Medicine, Winston-Salem, North Carolina, United States 2020 16 12 2020 16 12 2020 4 Suppl 1 Program Abstracts from The GSA 2020 Annual Scientific Meeting “Turning 75: Why Age Matters”650 650 © The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America.2020This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.Abstract Aromatase Inhibitors (AIs) are recommended for survival in hormone-sensitive breast cancer survivors, yet are underutilized, especially in older survivors. Joint pain is a prevalent AI-related symptom that is associated with low adherence. The aims for this randomized clinical trial (n=76) are to: 1) adapt a self-management (exercise + education) intervention for older survivors planning to take AIs; 2) Test the effect of a pilot intervention on arthralgia; and 3) Test its effect on AI medication adherence behaviors. We will adapt a program for seniors that includes bi-weekly 60-minute sessions of supervised exercise plus 30 minutes of education. The 16-week program includes: 8-weeks in person plus 8-weeks at home with phone counseling. We will conduct geriatric plus baseline assessment of exercise, joint pain, and AI adherence (repeated 4, 6 and 12 months). More research with geriatric survivors is required to address treatment needs and to promote survival. Part of a symposium sponsored by the Cancer and Aging Interest Group.