==== Front Indian J OphthalmolIndian J OphthalmolIJOIndian Journal of Ophthalmology0301-47381998-3689Medknow Publications & Media Pvt Ltd India 30038159IJO-66-114110.4103/ijo.IJO_792_18CommentaryCommentary: Office-based vitrectomy using topical anesthesia in an Indian setting Mohan Ashwin Venkatesh Ramesh Narayana Nethralya, Bangalore, Karnataka, India Correspondence to: Dr. Ashwin Mohan, 121/c 1st Block Rajajinagar, Bangalore - 560 010, Karnataka, India. E-mail: drashwinm@gmail.com8 2018 66 8 1141 1142 Copyright: © 2018 Indian Journal of Ophthalmology2018This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.Feasibility and safety of vitrectomy under topical anesthesia in an office-based setting ==== Body One of the earliest reports of office-based vitrectomy date back to the 1980s for selected diseases in rural Guatemala.[1] Office-based topical vitrectomy promises to be cost-effective,[2] avoids block-related complications, and offers better patient comfort while maintaining comparable visual outcomes. We feel that it would be better to analyze this in two separate parts: the topical anesthesia and the office-based setup. Modern cataract surgery has evolved from the intracapsular cataract extraction to the topical clear corneal phacoemulsification. Patients used to be patched overnight after the cataract surgery, however now they can see and are ambulatory a few hours after the operation. This is possible due to topical anesthesia and the smaller incisions and less surgical trauma. The visual outcomes are excellent and topical phacoemulsification is now the standard of care. Can vitrectomy too evolve to a topical approach? The answer to this lies in careful case selection. A few cases such as vitrectomy for floaters, epiretinal membrane peeling, macular hole surgeries, and vitrectomies for uncomplicated cases of vitreous hemorrhage are cases amenable to topical vitrectomy. Office-based vitrectomy, however, can offer prompt intervention in sight-threatening conditions such as endophthalmitis. Office-based vitrectomy can also be very useful for vitreous biopsies in conditions such as endophthalmitis and uveitic conditions where laboratory tests yield no clear diagnosis and vitreous biopsies for possible malignancies.[3] Other cases such as clearing of postoperative bleeding in diabetic cases are also good candidates. Cases involving steps other than three-port vitrectomy such as conjunctival dissection, buckle insertion, cryotherapy, or external subretinal fluid drainage would be better suited with local anesthesia that offers akinesia in addition to deeper anesthesia. More complicated cases involving peeling of tractional membranes in advanced vascular disease or chronic rhegmatogenous retinal detachments and subretinal bands would also be better suited with local anesthesia. Hence, we see that careful case selection is paramount for topical anesthesia. The patients are likely to face less pain with trocar insertion than during administration of the local anesthesia injections. However, during local anesthesia, maximum pain is felt during the first injection, and the following injections are subsequently less painful. With trocar insertions, however, each insertion would elicit the same degree of pain. Sanchez et al.[4] reported a case series of 34 eyes which underwent office-based vitrectomy under topical anesthesia. The patients comfort was evaluated using a questionnaire and > 75% of the patients were extremely comfortable during the surgery; about 18% of the patients experienced severe pain. One clear advantage of office-based vitrectomy would be the avoidance of anesthesia-related complications such as retrobulbar hemorrhage, globe perforation, optic nerve damage, and ptosis. An interesting point to consider is that patients under topical anesthesia would be more prone to squeezing of the eyelids and the rectus muscles. This could increase the intraocular pressure. Sudden decompression while removing the instruments out of the ports may predispose to choroidal hemorrhage. Hence, adequate care must be taken to never allow more than one port to be left open. In the study by Sanchez et al.,[4] the surgeons reported that > 85% of the cases were extremely comfortable. Endophthalmitis is a dreaded complication and every precaution must be taken to avoid it. Office-based intravitreal injections such as antivascular endothelial growth factor are routinely given in the West; however, it is still not practiced in India. This is because India being more densely populated developing nation, not only is the overall air quality poor and fraught with more particulate matter, the bacterial and viral loads also are more that would predispose to more airborne infections. This implies that sterility of the air would be paramount in the operative environment. It is thus essential to ensure that filtered sterilized air is maintained with adequate positive pressure to ensure that air only flows out of the doors of the room and not inward. Patient safety is top priority and the team in the office must be capable of providing first aid for adverse cardiovascular events. Supplemental oxygen, a pulse oximeter, and a sphygmomanometer should be available.[2] The office-based cutters though are far more portable and also cost-effective as compared to the conventional operation theater-based vitrectomies and hence may help reach far and wide where setting up of a full-fledged operation theater would be a challenge. However, it must be kept in mind that a well-informed and cooperative patient is important when such an office-based procedure is undertaken. India being a developing country the population at large is illiterate and thus patient cooperation must be thoroughly assessed before the procedure. If topical anesthesia is used, the surgery would be more challenging due to the absence of akinesia and possible patient noncooperation and hence a surgeon well experienced in pars plana vitrectomy in an operation theater-based setting would be better suited than a relatively inexperienced surgeon. In summary, office-based vitrectomy with topical anesthesia can be an excellent tool for prompt cost-effective intervention; however, careful patient selection, air sterility, and basic life support and first aid are a must. ==== Refs 1 Kingham JD Poirier RH Annel M Erickson D Use of portable vitrectomy instrumentation (VISC X) in the rural guatemalan highlands Br J Ophthalmol 1982 66 569 72 7104276 2 Shevchenko L Westhouse SJ Aaberg TM When Office-Based Vitrectomy Makes Sense. Retinal Physician Last accessed on 2018 May 10 Available from: https://www.retinalphysician.com/issues/2014/april-2014/when-office-based-vitrectomy-makes-sense 3 Hilton GF Josephberg RG Halperin LS Madreperla SA Brinton DA Lee SS Office-based sutureless transconjunctival pars plana vitrectomy Retina 2002 22 725 32 12476098 4 Trujillo-Sanchez GP Gonzalez-De La Rosa A Navarro-Partida J Haro-Morlett L Altamirano-Vallejo JC Santos A Feasibility and safety of vitrectomy under topical anesthesia in an office-based setting Indian J Ophthalmol 2018 66 1136 40 30038158