==== Front Rev Bras Ginecol Obstet Rev Bras Ginecol Obstet 10.1055/s-00030576 RBGO Gynecology & Obstetrics 0100-7203 1806-9339 Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil 30142670 10.1055/s-0038-1668532 18021502 Letter to the Editor Answer – Abortion and Zika Virus Congenital Infection Mota Vivian Maria Ribeiro 1 Delfino Alanna dos Santos 3 Lopes Thayse Elaine Costa Figueiredo 4 Pessoa André Luiz Santos 5 Ribeiro Erlane Marques 4 Cavalcanti Luciano Pamplona de Góes 2 1 Universidade de Fortaleza, Fortaleza, CE, Brazil 2 Universidade Federal do Ceará, Fortaleza, CE, Brazil 3 Universidade Estadual do Ceará, Fortaleza, CE, Brazil 4 Faculty of Medicine, Centro Universitário Christus, Fortaleza, CE, Brazil 5 Hospital Infantil Albert Sabin, Fortaleza, CE, Brazil Address for correspondence Vivian Maria Ribeiro Mota, MD Universidade de Fortaleza, Rua Vasco de Ataíde 89560841-395, Fortaleza, CEBrazilvivianmariaribeiromota@gmail.com 8 2018 1 8 2018 40 8 498498 https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ==== Body pmcWe would like to thank for the comments of the letter to the editor about our article “Abortion in Cases of Zika Virus Congenital Infection.”1 Intrauterine consequences have become a focus of concern when it comes to Zika virus infection.2 As for the first statement: “There is still no evidence that Zika virus infection in pregnant women is the cause of abortion,” in fact, there are records in the scientific literature that strongly suggest this association and report intrauterine fetal death and spontaneous abortion,3 4 both precocious4 and late,2 caused by the Zika virus and confirmed by serological tests on the fetus and the placenta. We agree with our colleagues about the statement that not all cases of maternal infection by the Zika virus have as a result a fetus with microcephaly. This was initially demonstrated by a series of cases of babies born with normal cephalic perimeter, despite the confirmation of infection of the mother.5 In view of these findings, there is no doubt that the maternal infection by the Zika virus is not a reliable evidence of fetal infection. However, in our article,1 we present data that indicate that pregnant women throughout the world, due to the psychological distress and the epidemiology of fetal infection, may be deciding whether to undergo an induced abortion after being infected by the Zika virus Thus, we reinforce the statement that: “Early diagnosis may be useful for some purposes such as epidemiological monitoring, but should not be the presumptive data for the decision on abortion for the pregnant woman infected with zika virus.” We believe that an early diagnosis provides the woman with a better understanding of the fetal situation, which empowers and enables her to decide what would be the best for her and the fetus, according to the law of each country. Conflicts of Interest None to declare. ==== Refs References 1 Mota V MR Cavalcanti L PG Delfino A DS Lopes T ECF Pessoa A LS Ribeiro E M Abortion in cases of Zika virus congenital infection Rev Bras Ginecol Obstet 2018 Jun 2910.1055/s-0038-1648219 2 Schaub B Monthieux A Najihoullah F Late miscarriage: another Zika concern Eur J Obstet Gynecol Reprod Biol 2016 207 240 241. doi: 10.1016/j.ejogrb.2016.10.04127837933 3 Goncé A Martínez M J Marbán-Castro E Spontaneous abortion associated with Zika virus infection and persistent viremia Emerg Infect Dis 2018 24 933 935. doi: 10.3201/eid2405.17147929664372 4 van der Eijk A A van Genderen P J Verdijk R M Miscarriage associated with Zika virus infection N Engl J Med 2016 375 1002 1004. doi: 10.1056/NEJMc160589827463941 5 van der Linden V Pessoa A Dobyns W Description of 13 infants born during October 2015–January 2016 with congenital Zika virus infection without microcephaly at birth - Brazil MMWR Morb Mortal Wkly Rep 2016 65 1343 1348. doi: 10.15585/mmwr.mm6547e227906905