
==== Front
JCEM Case Rep
JCEM Case Rep
jcemcr
JCEM Case Reports
2755-1520
Oxford University Press US

10.1210/jcemcr/luae162
luae162
Image in Endocrinology
AcademicSubjects/MED00010
AcademicSubjects/MED00160
AcademicSubjects/MED00250
AcademicSubjects/MED00300
AcademicSubjects/MED00905
Adrenal Hemangioma
Elsayes Ahmed K Department of Radiology, University of Texas Medical Branch Galveston, Galveston, TX 77555, USA

Waguespack Steven G Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA

Matta Eduardo J Department of Diagnostic and Interventional Imaging, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA

https://orcid.org/0000-0002-3457-9327
Wang Mindy X Department of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA

Correspondence: Mindy X. Wang, MD, Department of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1461, Houston, TX 77030, USA. Email: mxwang@mdanderson.org.
9 2024
16 9 2024
16 9 2024
2 9 luae16210 6 2024
24 8 2024
16 9 2024
© The Author(s) 2024. Published by Oxford University Press on behalf of the Endocrine Society.
2024
https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com. See the journal About page for additional terms.

adrenal gland neoplasms
hemangioma
pheochromocytoma
incidentaloma
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pmcImage Legend

A 69-year-old man with treated melanoma and prostate cancer presented for cancer restaging. Magnetic resonance imaging demonstrated a markedly enhancing, well-circumscribed 2.3-cm left adrenal mass (Fig. 1A). The mass retained contrast on venous and delayed phases (Fig. 1B and 1C), which is atypical for a benign adenoma. Thus, the lesion was considered indeterminate and suspicious for metastasis given the history of malignancy. After a negative hormonal evaluation, tissue biopsy revealed a hemangioma, with collections of small blood vessels within loose myxoid stroma. The patient had no biopsy-related complications, including bleeding. Retrospectively, some imaging features were characteristic of hemangioma: enhancement pattern following the blood pool and markedly increased signal intensity on T2-weighted images (Fig. 1D). Adrenal hemangioma is a rare, benign tumor representing less than 1% of adrenal tumors. They can be misdiagnosed as pheochromocytoma or metastasis (1, 2). Adrenal hemangiomas are usually nonfunctional and asymptomatic but can rarely present with symptoms of mass effect or hemorrhage (2). The diagnosis is usually made after tissue sampling or surgical resection, which may be necessary for symptomatic treatment, diagnostic purposes, or treatment of endocrine hyperfunction. In conclusion, adrenal hemangioma may portray classic imaging features; its diagnosis should be considered depending on the clinical context.

Funding

No public or commercial funding.

Disclosures

S.G.W. is an editorial board member for JCEM Case Reports and played no role in the journal's evaluation of the manuscript. All other authors: none declared.

Informed Patient Consent for Publication

Signed informed consent could not be obtained from the patient or a proxy but has been approved by the treating institution.

Data Availability Statement

Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study.
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References

1 Zuo  Y, Liang  Z, Yang  S, et al  Clinical characteristics of adrenal hemangioma. J Endocr Soc. 2024;8 (5 ):bvae041.38533349
2 Huang  T, Yang  Q, Hu  Y, Wu  H-X. Adrenal cavernous hemangioma misdiagnosed as pheochromocytoma: a case report. BMC Surg. 2021;21 (1 ):210.33902538
