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Neurooncol Adv
Neurooncol Adv
noa
Neuro-Oncology Advances
2632-2498
Oxford University Press US

10.1093/noajnl/vdae090.120
vdae090.120
Final Category: Supportive Care, Palliative Care and QOL
AcademicSubjects/MED00300
AcademicSubjects/MED00310
QSPC-01 INVESTIGATING DISTRESS LEVELS IN PATIENTS WITH METASTATIC SPINE DISEASE UNDERGOING SURGICAL INTERVENTION
Rowe Dana Duke University School of Medicine, Durham, NC, USA

O’Callaghan Ellen Duke University School of Medicine, Durham, NC, USA

Barrett Connor Duke University School of Medicine, Durham, NC, USA

Owolo Edwin Duke University School of Medicine, Durham, NC, USA

Charles Antoinette Duke University School of Medicine, Durham, NC, USA

Luo Emily Duke University School of Medicine, Durham, NC, USA

Arango Alissa Duke University School of Medicine, Durham, NC, USA

Bishop Brandon Duke University School of Medicine, Durham, NC, USA

Yoo Seeley Duke University School of Medicine, Durham, NC, USA

Johnson Margaret Duke University Hospital, Durham, NC, USA

Erickson Melissa Duke University Hospital, Durham, NC, USA

Goodwin C Rory Duke University Hospital, Durham, NC, USA

8 2024
02 8 2024
02 8 2024
6 Suppl 1 2024 SNO/ASCO CNS Metastases Conference i36i36
© The Author(s) 2024. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.
2024
https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

Abstract

INTRODUCTION

Cancer patients often experience high levels of distress, which are particularly pronounced in the perioperative period. However, there is a dearth of research on distress rates in patients with metastatic spine disease (MSD). This study aims to assess pre-operative and post-operative distress levels in patients with MSD undergoing surgical intervention.

METHODS/STUDY POPULATION

We retrospectively queried electronic medical records from a single institution for demographic and clinical data on patients with metastatic spine disease who underwent surgical intervention between 2015 and 2023. Data also included preoperative (within 60 days of surgery) and postoperative (within 30 days of surgery) National Comprehensive Cancer Network’s Distress Thermometer (NCCN-DT) scores.

RESULTS

We identified 222 patients with complete NCCN-DT questionnaires. Nearly half (46.4%) of the patients were female, with 71.2% identifying as White, and 68.5% being married or partnered. The median age at the time of spine metastasis diagnosis was 62.5 years (IQR: 53.0; 71.5). Preoperatively, the mean distress score was 3.5 (range 0-10), with 103 (46.4%) patients reporting moderate to severe distress (DT ≥ 4). The mean distress score at 30-days postop was 3.2 (range 0-10), with 43.75% of patients reporting moderate to severe distress. At 90-days post-op, the mean distress score was 2.3 (range 0-9) with 23.8% of patients reporting moderate to severe levels.

DISCUSSION/SIGNIFICANCE OF IMPACT

Distress is a common experience among patients with metastatic spine disease undergoing surgical intervention. Preoperatively, nearly half of these patients report moderate to severe distress. While distress rates generally decline postoperatively, a considerable proportion of patients continue to experience high levels of distress. These findings underscore the significance of addressing distress in this patient population.
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