
==== Front
bioRxiv
BIORXIV
bioRxiv
2692-8205
Cold Spring Harbor Laboratory

10.1101/2024.08.22.609228
preprint
1
Article
Bidirectional locomotion induces unilateral limb adaptations
Hardesty Russell L. http://orcid.org/0000-0001-5065-0157

Motjabavi Helia
Gemoets Darren E.
Wolpaw Jonathan R.
23 8 2024
2024.08.22.609228https://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator.
http://biorxiv.org/lookup/doi/10.1101/2024.08.22.609228
nihpp-2024.08.22.609228.pdf
Abstract

Humans can acquire and maintain motor skills throughout their lives through motor learning. Motor learning and skill acquisition are essential for rehabilitation following neurological disease or injury. Adaptation, the initial stage of motor learning, involves short-term changes in motor performance in response to a new demand in the person’s environment. Repeated adaptation can improve skill performance and result in long-term skill retention. Locomotor adaptation is extensively studied using split-belt treadmill paradigms. In this study we explored whether bidirectional walking (BDW) on a split-belt treadmill can induce short-term gait adaptations. Twelve healthy volunteers participated in our single session, starting with 2 minutes of normal walking (NW), followed by four 5-minute blocks of BDW with a 1-minute passive rest in between blocks, and ending with another 2-minute of NW. We recorded body kinematics and ground reaction forces throughout the experiment. Participants quickly adapted to BDW with both legs showing decreased step lengths. However, only the backward-walking leg exhibited aftereffects upon returning to NW, indicating short-term adaptation. Notable kinematic changes were observed, particularly in hip extension and pelvis tilt, though these varied among participants. Our findings suggest that BDW induces unilateral adaptations despite bilateral changes in gait, offering new insights into locomotor control and spinal CPG organization.

Key Points

Locomotor adaptation extensively studied using split-belt treadmill paradigms with asymmetric belt speeds.

This study examined whether bidirectional walking, i.e. walking with each leg stepping in opposite directions, would induce short-term adaptations in spatiotemporal characteristics of gait.

Volunteers performed bidirectional walking with bilateral changes in step length.

Despite equal but opposite belt speeds, volunteers exhibited a unilateral aftereffect of decreased step length in the leg which performed backwards stepping during bidirectional walking.
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pmc
