
==== Front
BMC Psychiatry
BMC Psychiatry
BMC Psychiatry
1471-244X
BioMed Central London

39223473
6041
10.1186/s12888-024-06041-2
Research
The association between child maltreatment, cognitive reappraisal, negative coping styles, and non-suicidal self-injury in adolescents with major depressive disorder
Li Yinglin 1
Wan Zhiying 2
Gong Xuan 2
Wen Li 1
Sun Ting 1
Liu Jingfang 2
Xie Xiangying 1
Zhang Chunlong 1
Cai Zhongxiang tg20201228@163.com

1
1 https://ror.org/03ekhbz91 grid.412632.0 0000 0004 1758 2270 Department of Nursing, Renmin Hospital of Wuhan University, Wuhan, 430060 China
2 https://ror.org/03ekhbz91 grid.412632.0 0000 0004 1758 2270 Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, 430060 China
2 9 2024
2 9 2024
2024
24 59230 1 2024
22 8 2024
© The Author(s) 2024
2024
https://creativecommons.org/licenses/by-nc-nd/4.0/ Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.
Background

Non-suicidal self-injury (NSSI) is a significant public health concern among adolescents with major depressive disorders (MDD). Although previous research has linked child maltreatment (CM) to NSSI, the precise mechanisms remain unclear. This study aims to investigate the association between CM, cognitive reappraisal (CR), negative coping styles (NC) and NSSI in adolescents with MDD, from the perspectives of both Latent Variable Theory and the Network Theory of Mental Disorder.

Methods

A sample of 651 adolescents with MDD was recruited from January to December 2023. Data on CM, CR, NC, and NSSI were collected through paper-based self-reported questionnaires. Data analysis primarily involved structural equation modeling and network analysis.

Results

The reporting rate of NSSI among adolescents with MDD was 48.2%. CM showed a significant positive correlation with NSSI. NSSI was affected by CM through three paths: the mediating role of CR, the mediating role of NC, and the chain mediating role of both CR and NC. Emotional abuse (EA) was the central node, while NSSI, EA, and “The urge to cry quietly when faced with troubles“(NC10) were the key bridge nodes.

Conclusions

This study is the first to use both structural equation modeling and network analysis to explore the explore the relationship between CM, CR, NC, and NSSI in adolescents with MDD, providing a theoretical basis for future early prevention and targeted interventions for adolescents with MDD.

Supplementary Information

The online version contains supplementary material available at 10.1186/s12888-024-06041-2.

Keywords

Non-suicidal self-injury
Child maltreatment
Negative coping styles
Cognitive reappraisal
Adolescents
Major depressive disorders
Hubei Province Key Laboratory Open Project2021KFH013 2022KFH001 Cross Innovative Talent Project of Renmin Hospital of Wuhan UniversityJCRCGW-2022-010 Wuhan Nursing Association Research ProjectWHHL202202 Wuhan University Clinical Nursing Special Research and Cultivation Fund ProjectLCHL202301 issue-copyright-statement© BioMed Central Ltd., part of Springer Nature 2024
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pmcIntroduction

In recent times, Non-Suicidal Self-Injury (NSSI) has emerged as a significant global public health concern [1]. It is now included in the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) as a condition requiring further study [2]. NSSI is defined as the deliberate act of harming one’s body tissues or organs without suicidal intent [3]. This behavior, while not fatal, is not socially sanctioned. Research indicates that over 66% of adolescents who have attempted suicide have a history of NSSI [4]. The average age of onset for NSSI in non-clinical samples is approximately 13 years [5], and its prevalence is notably high among adolescents [6], with an increasing annual recurrence rate [7, 8]. Globally, the prevalence rates are estimated to be between 18 and 23% [9, 10], posing a serious threat to the psychophysical well-being of adolescents [11]. These include increased risks of social difficulties, psychiatric disorders, and heightened suicidal ideation and attempts [12]. Furthermore, NSSI is prevalently observed within adolescent populations accompanied by major depressive disorder (MDD) and is regarded as one of the prime predictive indicators for suicidal behaviors [13]. MDD is a common, multifactorial, recurrent, and chronic psychological disorder and a leading cause of disability worldwide, considered a major contributor to the global disease burden among adolescents [14, 15]. Previous research has found that roughly 40–60% of adolescents with MDD have a history of NSSI [16, 17]. Therefore, clarifying the pathways of NSSI occurrence in adolescents with MDD is crucial for early identification and prevention of NSSI, as well as for devising targeted intervention strategies. Research indicates that NSSI is influenced by multiple interacting factors [18, 19]. However, the predominant contributing factors remain unconfirmed.

Child maltreatment (CM) is defined as any act or failure to act by parents or other caregivers occurring before the age of 18 [20]. It includes emotional abuse (EA), physical abuse (PA), sexual abuse (SA), emotional neglect (EN), and physical neglect (PN). In a representative sample in the United States, the estimated prevalence of maltreatment by age 18 is 12.5%. In the United Kingdom, the maltreatment rate among children and adolescents aged 11 to 17 is 18.6% [21].Research indicates that CM, particularly EA and EN, serves as distal risk factors for NSSI among adolescents with MDD [22]. A one-year follow-up of outpatients with treatment-resistant depression showed that those with a history of CM had more challenges alleviating depressive symptoms and poorer outcomes [23]. In a retrospective study of 2,232 children, it was reported that those with a history of CM displayed an elevated risk of mental health issues, including depression, anxiety, and self-harm, by age 18 [24]. However, the exact mechanism by which CM influences NSSI remains undetermined at present.

James Gross’s model explains the generation and regulation of emotions in detail, identifying Cognitive Reappraisal (CR) as an adaptive emotion regulation strategy that regulates emotions, reduces perceived threats [25], and mitigates the effects of child maltreatment on adolescent NSSI [26]. CR is an emotion regulation strategy that involves altering one’s emotional response by reinterpreting the initial cognitive assessment of a situation. Specifically, it entails transforming an automatically generated negative thought into a more positive or neutral interpretation, thus changing its emotional impact [27, 28]. Research has discovered a negative correlation between child maltreatment and CR, with maltreated children exhibiting less usage of CR compared to those not maltreated [29]. Some studies have compared CR with Expressive Suppression (ES), which is considered a non-adaptive emotion regulation strategy. Findings from these studies indicate that CR is more effective than ES in reducing both the risk and severity of NSSI [30, 31]. Beyond this, CR has also been demonstrated to enhance individual stress coping mechanisms, subjective well-being, interpersonal relationships, and even alleviate physical discomfort [32]. Among offender populations, CR has been validated to diminish the impact of child maltreatment on NSSI [33]. Therefore, for adolescents who have experienced child maltreatment, effective utilization of CR may serve as a protective factor, aiding in the reduction of the risk associated with NSSI.

Conversely, the coping process model by Compas highlights that negative coping styles (NC), such as avoidance, suppression, and self-blame, may exacerbate negative effects [34]. Particularly for adolescents with a history of maltreatment, these negative strategies may worsen psychological trauma, thereby increasing the risk of NSSI. Coping strategies are cognitive processes and behaviors that an individual employs to manage or prevent harm and loss [35], and can be categorized as either positive or negative [36]. Recent research suggests that NC is associated with an increased risk of NSSI [37], and is significantly and positively correlated with child maltreatment, whereas individuals without a history of child maltreatment are more likely to adopt positive coping strategies [38].

According to the integrative theoretical model by Nock [39], the presence of distal risk factors such as child maltreatment may be associated with individual or interpersonal vulnerability factors for NSSI, such as poorer emotion regulation strategies [29]. A diminished capacity for cognitive reappraisal may exacerbate their reliance on negative coping styles, is associated with individuals adopting excessive or socially non-conforming coping mechanisms in the face of stressful events. Consequently, they may be more likely to resort to NSSI as a means to regulate emotions and navigate social situations.

Based on current research, hypotheses are (see Fig. 1): Child maltreatment is positively associated with NSSI; cognitive reappraisal and negative coping styles mediate the association between child maltreatment and NSSI respectively; cognitive reappraisal and negative coping styles play a chained mediating role in the association between child maltreatment and NSSI.

Despite extensive prior research on the association between child maltreatment and NSSI, no studies have been found to concurrently examine the association among child maltreatment, cognitive reappraisal, negative coping styles, and NSSI from the perspectives of both Latent Variable Theory and the Network Theory of Mental Disorder. Latent Variable Theory posits that some variables (latent variables) cannot be directly observed or measured but can be indirectly inferred and measured through other observable variables (observed variables). While the Structural Equation Model (SEM) is effective in exploring the relationships between multiple latent variables simultaneously, it may overlook individual nuances and dynamic interactions among these variables [40]. In contrast, the Network Theory of Mental Disorder conceptualizes mental disorders as complex systems of interrelated and often mutually reinforcing symptoms [41]. Network analysis (NA) emphasizes direct interactions between individual symptoms and reveals potential complex interaction patterns among variables [42]. This study aims to explore both the associations and potential pathways of child maltreatment on NSSI among adolescents with MDD by using SEM. Concurrently, a symptom network will be established to analyze the interrelationships at the symptom level among child maltreatment, cognitive reappraisal, negative coping styles, and NSSI, identifying key nodes associated with NSSI.

Thus, integrating these methods allows researchers a more comprehensive and nuanced understanding of the relationships involved, presenting a methodological innovation that offers fresh insights into the associations underlying NSSI in adolescents with MDD, thereby aiding in effective and precise prevention and intervention strategies.

Fig. 1 The hypothesis model

Methods

Participants and procedure

Participants for the current study were recruited patients diagnosed with MDD from the psychiatry department of Renmin Hospital of Wuhan University from January to December 2023. To ensure diagnostic rigor, two experienced psychiatrists diagnosed the patients using the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) [43]. Inclusion criteria included: (1) Ages 13–25 (The definition of the age of adolescents by the Chinese Public Security Department); (2) Diagnosis of an MDD based on DSM-5 standards; (3) Written consent from both the patient and their family. Exclusion criteria included: (1) Severe suicidal behavior, refusal to eat, or catatonia; (2) Serious drug side effects or major physical illnesses; (3) A history of brain-related organic disorders; (4) Co-occurrence of other psychiatric disorders.

To ensure a high response rate, researchers distributed paper questionnaires in person, assisted participants during the filling process, and collected them on the spot. Out of 700 questionnaires distributed, after excluding those with numerous missing entries due to participants discontinuing midway for personal reasons, 651 questionnaires remained valid, resulting in an effectiveness rate of 93.0%.

All participants signed a written informed consent form before participating in the study. Those under 18 obtained written permission from their parents. It took participants approximately 20 to 30 min to complete all the questions. The survey was conducted according to the latest version of the Declaration of Helsinki. This study was approved by the Ethics Committee of Renmin Hospital of Wuhan University (NO: 2023K-K165).

Measures

Non-suicidal self-injury (NSSI)

The Adolescent Non suicidal Self-Injury Behavior Questionnaire (ANSAQ) [44] is often used to assess non-suicidal self-injury behavior and functions in Chinese adolescents. The ANSAQ is divided into two sections: a behavior questionnaire and a function questionnaire. This study utilized the behavior questionnaire (Part One) to measure NSSI behavior, consisting of 12 items, scored using a Likert five-point scale ranging from 0 (never) to 4 (always). Higher scores indicate a greater severity of NSSI. Based on DSM-5 diagnostic criteria [45] and a structured interview with two trained psychiatrists, the patients included in the study were divided into groups with and without NSSI. In this study, the scales demonstrated good internal consistency (Cronbach’s alpha = 0.893).

Child maltreatment

The Childhood Trauma Questionnaire Short Form (CTQ-SF) [46] assesses emotional abuse(EA), physical abuse(PA), sexual abuse(SA), physical neglect(PN), and emotional neglect(EN). The CTQ-SF consists of 28 items, using a Likert five-point scale ranging from 1 (never) to 5 (always), with seven items scored in reverse. If the score for any subscale exceeds the relevant threshold, the participant is considered to have experienced child maltreatment: PA (> 9), SA (> 7), EA (> 12), PN (> 9), and EN (> 14) [47]. The Cronbach’s alpha coefficients for EA, PA, SA, PN, and EN were 0.827, 0.836, 0.849, 0.603, and 0.827, respectively. Except for PN, the four dimensions of the CTQ-SF demonstrated good internal consistency in this study. Therefore, the dimension of PN was excluded from subsequent data analyses.

Cognitive reappraisal

The Emotion Regulation Questionnaire (ERQ) [48] assesses emotion regulation strategies. The ERQ is divided into two subscales: cognitive reappraisal and expression suppression, encompassing a total of 10 items. This study utilized the cognitive reappraisal subscale to measure cognitive reappraisal, consisting of 6 items, with a Likert seven-point scale ranging from 1 (strongly disagree) to 7 (strongly agree). Higher scores indicate a higher frequency of employing cognitive reappraisal strategies. In the current sample, good internal consistency was demonstrated (Cronbach’s alpha = 0.866).

Negative coping styles

The Trait Coping Style Questionnaire [49] evaluates participants’ coping styles in response to life events. The questionnaire consists of two subscales: positive coping and negative coping, with a total of 20 items. This study focused on the negative coping subscale, which includes 10 items, utilizing a Likert five-point scale ranging from 1 (definitely no) to 5 (definitely yes). Higher scores indicate a greater intensity of negative coping methods. In the current sample, good internal consistency was exhibited (Cronbach’s alpha = 0.786).

Data analysis

SPSS (version 25.0) was used for descriptive statistics, Pearson correlation analysis, analysis of variance (ANOVA), and common method bias analysis. All data used in the structural equation model and network analysis were continuous variables.

Amos (version 28.0) was used for structural equation modeling analysis. Within this model, CM, represented by EA, PA, EN, and SA, served as the independent variable, while NSSI was the dependent variable. Cognitive reappraisal and negative coping styles functioned as mediating variables. Model fit indices comprised χ2/df (< 5), the comparative fit index (CFI > 0.90), the Tucker-Lewis index (TLI > 0.90), and the root mean square error of approximation (RMSEA < 0.08) [50]. Bootstrap analysis was used to investigate the mediating effects using 5000 bootstrap samples, with direct, indirect, and total effects being concurrently calculated.

R (version 5.4.1) was used for network analysis. In the network, each item (symptom) is represented as a node, and the associations between items are represented as edges. Thicker edges indicate stronger relationships between nodes. Nodes with stronger and more frequent connections are more concentrated in the network, forming dense areas. A community is a group of nodes (symptoms) that are more closely connected to each other than to nodes outside the group. A bridge is an edge that connects nodes from different communities. Edge color indicates the correlation between nodes: red denotes a negative correlation, while purple denotes a positive correlation. The qgraph package (Version 4.2.3) [51] was used for network estimation. Given that all data are derived from Likert scales, approximating continuous variables, partial correlation analysis is employed to calculate the association of each symptom, after controlling for all other variables included in the network [52]. The Least Absolute Shrinkage and Selection Operator (LASSO) method [53] was used to diminish spurious edges in the network, while the Extended Bayesian Information Criterion (EBIC) was used to select the optimal fitting model, with a tuning parameter of 0.5 [54]. Node centrality was applied to quantitatively describe the structural importance of each node in the network, identifying the more influential nodes [55]. Evidence suggests that EI is particularly apt for determining nodes in networks with both positive and negative connections [56]. Centrality metrics were given as z-score values. The networktools package (version 4.2.2) was used to calculate bridge centrality [57], with bridge expected influence (1-step) serving as the bridge centrality in this study. The mgm package (version 1.2–14) [58] was used for estimating the predictability of each node. The bootnet package (Version 1.4.3) [52] was used to assess the accuracy and stability of network estimation through bootstrap methods. Accuracy was estimated by plotting the 95% confidence intervals (CI) of edge weights, while stability was assessed both graphically and quantitatively by calculating the correlation stability coefficient (CS-coefficient). The CS coefficient should not be lower than 0.25 and is preferably above 0.5.

In studying adolescent NSSI, a strong correlation between age and NSSI persists. Therefore, this study controls for age by including it as a covariate. In this study, 95% CI that did not include zero signified significant effects. A two-sided P-value < 0.05 indicated significant differences.

Results

Test of common method bias

To control for the common method bias problem, Harman’s single-factor test was conducted. Results yielded nine factors with eigenvalues > 1, and the first unrotated factor accounted for 21.91% of the variance, falling below the 40% threshold, indicating no significant common method bias in this study [59].

Participant characteristics

The study included 651 participants, aged 13 to 25 years.48.2% (314 participants) reported engaging in NSSI. The detection rates for emotional abuse, emotional neglect, physical abuse, and sexual abuse were 32.7%, 49.9%, 20.1%, and 14.7%, respectively. Table 1 presents details characteristics on age, gender, nation, religion, only child status, birthplace, education, left-behind children status, and first episode for first occurrence of MDD.

Table 1 Characteristics of participants, n(%) (N = 651)

Characteristics	No NSSI	NSSI	χ2	Cramér’s V	p-value	
Age			20.897	0.179	< 0.001**	
 13 ~ 19	136(40.4)	183(58.3)				
 20 ~ 25	201(59.6)	131(41.7)				
Gender	13.802	0.146	< 0.001**	
 male	139(41.2)	86(27.4)				
 female	198(58.8)	228(72.6)				
Nation	0.000	0.001	0.986	
 Han	321(95.3)	299(95.2)				
 minority	16(4.7)	15(4.8)				
Religion	5.471	0.092	0.019*	
 yes	6(1.8)	16(5.1)				
 no	331(98.2)	298(94.9)				
Only children	2.833	0.066	0.092	
 yes	196(58.2)	162(51.6)				
 no	141(41.8)	152(48.4)				
Birthplace	3.554	0.074	0.169	
 urban	141(41.8)	142(45.2)				
 town	98(29.1)	101(32.2)				
 rural	98(29.1)	71(22.6)				
Education			26.554	0.202	< 0.001**	
 middle school and below	33(9.8)	76(24.2)				
 high school	113(33.5)	104(33.1)				
 college	191(56.7)	134(42.7)				
Left-behind children			5.697	0.094	0.017*	
 yes	59(17.5)	79(25.2)				
 no	278(82.5)	235(74.8)				
First episode			2.845	0.066	0.092	
 yes	123(36.5)	95(30.3)				
 no	214(63.5)	219(69.7)				
Age groups are defined per WHO’s adolescent age definition into 10–19 [60] and 20–25 years; Left-behind children [61] defined as those who remain in their hometowns under the care of other relatives such as grandparents, other family members, or guardians, while at least one parent works away from home or is absent for an extended period before the child turns 18. First episode refers to the first occurrence of MDD

*P < 0.05

**P < 0.01

Correlation of child maltreatment, cognitive reappraisal, negative coping styles, and NSSI

The means, standard deviations, and bivariate correlations among the study variables are presented in Table 2. Emotional abuse, physical abuse, sexual abuse, emotional neglect, negative coping styles, and NSSI were all significantly and positively associated with each other (p < 0.05). In contrast, cognitive reappraisal was significantly and negatively associated with the other variables (p < 0.05). Importantly, tolerance values for emotional abuse, physical abuse, sexual abuse, emotional neglect, negative coping styles, and cognitive reappraisal were all above 0.1, and the Variance Inflation Factor (VIF) values were below 5, suggesting no multicollinearity issues.Table 2 Means, standard deviations, and bivariate correlations among study variables (N = 651)

Variables	Emotional Abuse	Emotional Neglect	Physical Abuse	Sexual Abuse	Cognitive Reappraisal	Negative Coping Styles	NSSI	
Emotional Abuse	1							
Emotional Neglect	0.497**	1						
Physical Abuse	0.603**	0.358**	1					
Sexual Abuse	0.279**	0.176**	0.234**	1				
Cognitive Reappraisal	− 0.318**	− 0.224**	− 0.189**	− 0.086*	1			
Negative Coping Styles	0.360**	0.152**	0.213**	0.145**	− 0.378**	1		
NSSI	0.465**	0.183**	0.297**	0.158**	− 0.391**	0.466**	1	
M	10.78	14.17	7.50	6.08	25.29	34.98	7.10	
SD	5.02	5.57	3.63	2.57	7.47	6.68	7.90	
NSSI Non-suicidal self-injury

*P<0.05

**P<0.01

Structural equation Model

Figure 2 illustrates the chain mediation model depicting the association between child maltreatment, cognitive reappraisal, negative coping styles and NSSI. The mediation values of cognitive reappraisal and negative coping styles in these associations are provided in Table 3. The data fit the hypothesized chain mediation model well, as evidenced by the following fit indices: χ2/df = 2.823, p < 0.001; CFI = 0.913; TLI = 0.901; and RMSEA = 0.053. In line with our expectations, both cognitive reappraisal and negative coping styles were significantly associated with the relationship between child maltreatment and NSSI. The model revealed a total effect of child maltreatment on NSSI of 0.466 (p < 0.001, 95% CI [0.388, 0.538]) and a direct effect of 0.288 (p < 0.001, 95% CI [0.203, 0.376]). Mediation accounted for 38.10% of the total effect. The path from child maltreatment to NSSI through cognitive reappraisal is significant (Estimate = 0.048, p = 0.001, 95% CI [0.021, 0.077]), contributing to 10.2% of the total effect. The path from child maltreatment to NSSI through negative coping styles is significant(Estimate = 0.091, p < 0.001, 95% CI [0.062, 0.129]), contributing to 19.5% of the total effect. The path from child maltreatment to NSSI through both cognitive reappraisal and negative coping styles is significant (Estimate = 0.039, p < 0.001, 95% CI [0.024, 0.061]), contributing to 8.4% of the total effect. The difference between the mediating effects of cognitive reappraisal and negative coping styles (DIFF1) was significant (p < 0.05), as was the difference between the mediating effect of negative coping styles and the chain mediating effect (DIFF3) (p < 0.05). However, the difference between the mediating effect of cognitive reappraisal and the chain mediating effect (DIFF2) was not significant. The negative estimate of DIFF1 indicates that cognitive reappraisal has a weaker effect compared to negative coping styles, while the positive estimate of DIFF3 suggests that negative coping styles have a stronger effect than the chain mediating effect.

Fig. 2 The chain mediation model for childhood maltreatment, cognitive reappraisal, negative coping styles and NSSI. *** < 0.001

Table 3 CM and NSSI in the mediation effect analysis

Relationship	Estimate	S.E.	95%CI	p	Ratio of indirect to total effect	
Lower	Upper	
CM→CR	-0.346	0.044	-0.431	-0.258	< 0.001		
CM→NC	0.283	0.043	0.198	0.369	< 0.001		
CR→NC	-0.353	0.049	-0.443	-0.251	< 0.001		
CR→NSSI	-0.138	0.041	-0.214	-0.054	0.002		
NC→NSSI	0.320	0.040	0.237	0.394	< 0.001		
Direct effect	0.288	0.044	0.203	0.376	< 0.001		
Mediating effect of CR	0.048	0.014	0.021	0.077	0.001	10.2%	
The mediating effect of NC	0.091	0.016	0.062	0.129	< 0.001	19.5%	
Chain mediating effect	0.039	0.009	0.024	0.061	< 0.001	8.4%	
Total indirect effect	0.177	0.022	0.139	0.226	< 0.001	38.1%	
Total effect	0.466	0.038	0.388	0.538	< 0.001		
DIFF1	-0.043	0.022	-0.088	-0.001	0.044		
DIFF2	0.008	0.018	-0.033	0.040	0.662		
DIFF3	0.052	0.019	0.017	0.091	0.005		
All variables in the model have been standardized

DIFF1: the difference between the mediating effects of cognitive reappraisal and negative coping styles

DIFF2: the difference between the mediating effect of cognitive reappraisal and the chain mediating effect

DIFF3: the difference between the mediating effect of negative coping styles and the chain mediating effect

Network analysis

The structure of the CM-CR-NC-NSSI network is depicted in Fig. 3. Four strongest edges are between EA-PA (weight = 0.41), EA-EN (weight = 0.29), CR3-CR10 (weight = 0.28) and CR7-CR8 (weight = 0.27). Within the CM community, EA demonstrated the strongest correlation with NSSI (weight = 0.24). In the CR community, CR10 showed the strongest correlation with NSSI (weight = -0.06). Within the NC community, NC17 had the strongest correlation with NSSI (weight = 0.19). Across the CM and CR communities, the strongest correlation was between EA and CR1 (weight = -0.04); between the CM and NC communities, the strongest was between EA and NC19 (weight = 0.05); and between the CR and NC communities, the strongest link was between CR5 and NC6 (weight = -0.09). All edge weights within the CM-CR-NC-NSSI network can be found in Table S1 (in Supplemental Material). The bootstrapped 95%CI for these edges is relatively narrow, indicating a relatively accurate estimation of the edge weights (Fig. S1 in Supplementary Material).

The network’s overall mean predictability is 0.354, meaning the average variance for each node, as explained by its directly connected nodes, is 35.4%. The predictability of all nodes can be found in Table S2 (in Supplemental Material).

Figure 4 depicts the node and bridge centrality, both expressed as z-scores, within the CM-CR-NC-NSSI network. Within this network, EA (EI:1.110) stands out with the highest node centrality, underscoring its dominant influence. NSSI (BEI:0.389) possesses the greatest bridge centrality, suggesting its significant impact on other communities, followed by EA (BEI:0.259) and “The urge to cry quietly when faced with troubles” (NC10; BEI:0.106). NSSI is most closely connected to “Blames and resents oneself for difficulties” (NC17) from other communities, EA and NC10 are most closely connected to NSSI from other communities. The EI and BEI of all nodes can be found in Table S3 (in Supplemental Material). The CS coefficients for both node and bridge expected influences are 0.594 and 0.673, respectively, demonstrating their substantial stability (Fig. S2 and Fig.S3 in Supplementary Material). Fig. S4 and Fig. S5 (in Supplementary Material) present the bootstrapped difference tests for node centrality and edge weights.

Fig. 3 Network structure of CM-CR-NC-NSSI symptoms. Purple edges represent positive correlations, red dashed edges represent negative correlations. The thickness of the edge reflects the magnitude of the correlation. Cut value = 0.05

Fig. 4 The node centrality (EI) and bridge centrality (BEI) of the CM-CR-NC-NSSI network (z-score)

Discussion

This is the first study to explore the association between child maltreatment, cognitive reappraisal, negative coping styles and NSSI in adolescents with MDD from both a macro (Structural Equation Model) and micro (Network Analysis) perspective. In this study, after controlling for age, the associations between variables are as follows: child maltreatment is directly associated with NSSI. Cognitive reappraisal is negatively associated with NSSI and mediates the relationship between child maltreatment and NSSI. Negative coping styles are also directly associated with NSSI and serve as a mediator between child maltreatment and NSSI. Together, cognitive reappraisal and negative coping styles form a serial mediation pathway linking child maltreatment to NSSI. More frequent use of negative coping styles and less frequent use of cognitive reappraisal are associated with a stronger association between child maltreatment and NSSI. Core symptoms identified in the network include emotional abuse (EA); key bridge symptoms at the symptom include NSSI, EA, and “The urge to cry quietly when faced with troubles” (NC10).

In the present study, the prevalence of NSSI among adolescents with MDD was 48.2%, aligning with previous studies where it exceeded 40% [17, 62], underscoring the severity of NSSI in this demographic. Compared to other types of child maltreatment, emotional neglect had the highest prevalence (49.9%), while sexual abuse had the lowest prevalence (14.7%), which is consistent with the study by Yu et al. [63]. However, prevalence rates may vary across studies depending on factors such as research methodology, sample selection criteria (e.g., age and gender distribution), measurement instruments used for assessing child maltreatment as well as regional and cultural differences.

This study validated the association between child maltreatment and NSSI in adolescents with MDD. The results of the network analysis revealed that emotional abuse (EA) was most strongly associated with NSSI in both communities, child maltreatment and NSSI, which is consistent with previous research [64]. Multiple studies have demonstrated that there is a positive correlation between EA and NSSI. Adolescents and adults who have endured EA are more prone to turn to NSSI as a coping strategy to alleviate their psychological distress [65, 66], a behavior that may stem from their attempts to control or escape the negative emotions associated with their abusive experiences. Simultaneously, EA emerges as a central node within the overarching network, significantly influencing the its stability. However, Misiak et al. found sexual abuse to be the most central symptom in their network analysis, a finding inconsistent with this study [67]. This discrepancy may stem from regional or cultural differences. In China, traditional educational approaches often emphasize authority and obedience. High expectations and strict discipline might lead to emotional abuse being overlooked or normalized within family and school settings, exacerbating its impact [68, 69].The prevention of EA, along with subsequent interventions, is crucial in averting long-term psychological damage and fostering recovery.

The current study suggests that cognitive reappraisal may partially mediate the association between child maltreatment and NSSI. When a person experiences a traumatic event, such as child maltreatment, their brain may develop a heightened stress response. This response may be associated with a greater tendency toward negative emotions when faced with stress [70]. To cope with these emotions, they may use different emotion regulation strategies, including cognitive reappraisal. However, not all individuals who have experienced child maltreatment use cognitive reappraisal effectively. Several studies have suggested that abuse experiences may be associated with changes in certain brain areas, such as the prefrontal cortex and amygdala, which are associated with emotion regulation and decision-making [71]. Additionally, Schore’s psychoneurobiological model suggests that individuals with insecure attachments in infancy may be less likely to develop effective emotion regulation skills [72]. Thus, for these individuals, even if they try to use cognitive reappraisal, it may be difficult to effectively regulate emotion, resulting in NSSI. This may be one of the reasons why cognitive reappraisal had a lesser mediating role in the results of this study. Helping infants develop secure attachments may be an effective method for enhancing emotional regulation skills in adolescents. Attachment-based family therapy can enable adolescents to identify and express emotions to their parents, potentially re-establishing secure attachment relationships [73].

The greater association of negative coping styles compared to cognitive reappraisal in mediating the association between child maltreatment and NSSI was evident in both SEM and NA results. Individuals with extensive child maltreatment histories are more likely to rely on negative coping styles such as wishful thinking, problem avoidance, social withdrawal, and self-criticism [74], and elevated levels of negative coping styles have been linked to an increased risk of NSSI [36]. Child maltreatment often imposed by parents or caregivers, creates an unhealthy environmental backdrop where children may develop significant interpersonal trust issues and learned helplessness. Consequently, these individuals might resort to maladaptive coping strategies such as smoking, excessive alcohol consumption, drug dependency, or engaging in NSSI. These behaviors may serve as means to alleviate their profound feelings of emptiness and insecurity [36, 75]. Among the three communities of child maltreatment, negative coping styles, and NSSI, EA is strongly associated with “Preferring to be alone when distressed” (NC19). This tendency to be “alone” may be an avoidance strategy to avoid confronting problems or painful emotions. Excessive solitude may hinder effective problem-solving and restrict access to support or other forms of assistance, potentially leading to chronic low levels of social support and an increased risk of depression. Research indicates that support sources differ by age, with parental support playing a crucial role for children and adolescents [76]. The “Blames and resents oneself for difficulties” (NC17) shows the strongest correlation with NSSI. Such intense self-blame and guilt may be associated with low self-esteem, feelings of helplessness, or diminished self-efficacy, all of which are prevalent in various mental health issues and are linked to an increased risk of NSSI [77, 78].

We also illustrated the potential chain mediation pathway of cognitive reappraisal and negative coping styles in the association between child maltreatment and NSSI, a contribution that may deepen our comprehension of this complex interrelation. When faced with negative life events such as child maltreatment, the failure of cognitive reappraisal as an emotion regulation strategy may result in individuals exhibiting negative coping behaviors, which could be associated with NSSI. This finding is consistent with Nock’s integrative theoretical model [39].

In the network model, a higher bridge EI indicates a greater likelihood of activating the communities connected by the nodes. We identified three key bridge symptoms: NSSI, emotional abuse (EA), and “The urge to cry quietly when faced with troubles” (NC10). Notably absent was a node for cognitive reappraisal, further corroborating the SEM outcomes of this study, which highlighted the mediating effect of negative coping styles as the most substantial among the three intermediary pathways examined. This is consistent with the findings of Voon et al., suggesting that adolescents who engage in NSSI are more likely to use emotion regulation processes that exacerbate negative emotional states compared to their non-NSSI peers, rather than those that could reduce these emotions (i.e., cognitive reappraisal) [31]. Within this framework, prioritizing the prevention of EA and education on appropriate coping strategies becomes particularly critical. Preventing EA requires efforts not just at the individual level, but also a collective commitment from various sectors of society, especially within educational and familial settings. This may involve enhancing awareness of EA, increasing public consciousness of its potential dangers, and establishing effective intervention mechanisms. Additionally, providing essential psychological support to patients who have endured child maltreatment, including counseling, emotion management skills training, and the establishment of support networks, is a crucial step. Concurrently, patients can be taught proper coping techniques through well-established psychological therapies, such as cognitive-behavioral therapy (CBT), coping skills training, and mindfulness practices. These approaches aim to assist patients in developing more adaptive coping mechanisms, bolstering psychological resilience, and thereby maintaining emotional stability when confronted with negative life events [79, 80]. In terms of cognitive reappraisal, due to the association between MDD in adolescents and difficulties with cognitive reassessment, adolescents with MDD report using cognitive reappraisal less frequently [81]. It is crucial to focus on teaching them effective cognitive reappraisal strategies, enabling adolescents with MDD to better and more effectively use cognitive reappraisal strategies. Emotion Regulation Training [82], Cognitive Behavioral Therapy (CBT) and Mindfulness-Based Cognitive Therapy (MBCT) [83] can all be instrumental in this regard.

There are several limitations to this study. First, as a single-center cross-sectional study, it primarily reveals correlations between child maltreatment, cognitive reappraisal, negative coping styles, and NSSI without establishing causality. The findings, therefore, may not be generalizable across different populations or settings. To address this, future research should consider multicenter longitudinal studies. Such studies would not only clarify causality but also offer insights into the temporal dynamics of these relationships and their variation across diverse demographic and cultural backgrounds. Additionally, the questionnaires used in this study were self-reported, and recall bias may occur. A significant limitation was the exclusion of the PN dimension due to poor internal consistency in the measurement tools. This low internal consistency could be attributed to the tools themselves or potentially to issues in the data collection process, such as inconsistencies in how participants understood or responded to the questions. This exclusion limits our understanding of the full spectrum of child maltreatment. Future research should not only focus on developing or identifying more reliable and valid tools to assess the PN dimension but also ensure that the data collection process is rigorous and standardized. This could involve pilot testing the tools to refine questions for clarity and consistency, training researchers to ensure uniform administration of the survey, and employing methodologies that reduce the likelihood of misinterpretation or inconsistent responses. Another significant limitation of our study is its exclusive focus on MDD, intentionally excluding other psychiatric disorders to reduce confounding factors and accentuate the unique characteristics of MDD. However, the high prevalence of comorbidity between MDD and other psychiatric conditions, especially among individuals with a history of trauma, constrains the generalizability of our findings. This methodological decision limits our insights to a narrow subgroup of MDD patients who do not present with additional psychiatric disorders. Future research should include a more diverse sample of psychiatric comorbidities to enhance the generalizability and practical utility of the findings. Finally, regarding the inclusion criteria of this study, the age range for adolescents with MDD was determined based on the standards set by China’s Ministry of Public Security. However, early adulthood (e.g., 21–25 years) is characterized by significantly different neural and cognitive development compared to adolescence (13–15 years), and individuals in these age groups face different challenges and environmental influences. Therefore, a more detailed comparative analysis of MDD patients in middle/high school versus those in university or the workforce would be beneficial. Future research should consider factors such as neural and cognitive development to more accurately define adolescence. This approach will enhance the comparability of findings across different cultural contexts and improve the targeting of prevention and intervention strategies.

Conclusions

This study is the first to use both structural equation modeling and network analysis to explore the association between child maltreatment, cognitive reappraisal, negative coping styles, and NSSI in adolescents with MDD. This study found that in the mediation between child maltreatment and NSSI, the mediating role of negative coping styles is relatively more pronounced. This might be associated with the physiological mechanisms impacted by child maltreatment, which affect the effective use of cognitive reappraisal in adolescents with MDD. Concurrently, the study identified both central symptom (EA) and bridge symptoms (NSSI, EA, and NC10 "The urge to cry quietly when faced with troubles”). The integration of these two approaches, examining both macroscopic and microscopic (symptomatic) perspectives, mutually reinforces their validity, providing a theoretical basis for early prevention and targeted intervention of NSSI in adolescents with MDD. The study emphasizes the importance of incorporating strategies to enhance cognitive reappraisal and reduce negative coping styles in therapeutic interventions for adolescents who have experienced child maltreatment.

Supplementary Information

Supplementary Material 1

Acknowledgements

We thank all the participants for completing the questionnaires.

Authors’ contributions

Yinglin Li: Methodology, Data collection, Formal analysis, Investigation, Writing - original draft. Zhiying Wan: Methodology, Data collection, Formal analysis, Investigation, Writing - original draft. Zhongxiang Cai: Conceptualization, Methodology, Supervision. Xuan Gong: Methodology, Writing - review & editing, Supervision. Li Wen: Conceptualization, Methodology, Supervision. Ting Sun: Investigation, Writing - review & editing. Jingfang Liu: Data collection, Investigation.Xiangying Xie: Data collection, Writing - review & editing, Investigation. Chunlong Zhang: Data collection, Investigation.

Funding

This work was supported by grants from the Hubei Province Key Laboratory Open Project (2021KFH013, 2022KFH001), the Cross Innovative Talent Project of Renmin Hospital of Wuhan University (JCRCGW-2022-010), the Wuhan Nursing Association Research Project (WHHL202202), and Wuhan University Clinical Nursing Special Research and Cultivation Fund Project (LCHL202301).

Availability of data and materials

The datasets generated andanalyzed during the current study are not publicly available but are available from the corresponding author on reasonable request.

Declarations

Ethics approval and consent to participate

We obtained written informed consent from patients or their legal guardians.

The survey was conducted according to the latest version of the Declaration of Helsinki. This study was approved by the Ethics Committee of Renmin Hospital of Wuhan University (NO: 2023K-K165).

Consent for publication

Not applicable.

Competing interests

The authors declare no competing interests.

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Yinglin Li and Zhiying Wan contributed equally to this work.
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