
==== Front
Nat Commun
Nat Commun
Nature Communications
2041-1723
Nature Publishing Group UK London

38763986
48568
10.1038/s41467-024-48568-8
Article
RETRACTED ARTICLE: Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats
http://orcid.org/0000-0003-1387-2054
Steinfeldt Jakob 12345
http://orcid.org/0000-0002-7492-8448
Wild Benjamin 6
Buergel Thore 56
http://orcid.org/0000-0003-3437-9963
Pietzner Maik 378
http://orcid.org/0000-0002-0966-4458
Upmeier zu Belzen Julius 6
Vauvelle Andre 9
http://orcid.org/0000-0002-2145-3258
Hegselmann Stefan 1011
Denaxas Spiros 9121314
http://orcid.org/0000-0003-2279-0624
Hemingway Harry 91314
http://orcid.org/0000-0002-5017-7344
Langenberg Claudia 378
http://orcid.org/0000-0002-0214-3203
Landmesser Ulf 1241516
Deanfield John 5
http://orcid.org/0000-0002-0034-4036
Eils Roland roland.eils@charite.de

617
1 https://ror.org/01mmady97 grid.418209.6 0000 0001 0000 0404 Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité (DHZC), Berlin, Germany
2 grid.7468.d 0000 0001 2248 7639 Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Klinik/Centrum, Charitéplatz 1, 10117 Berlin, Germany
3 https://ror.org/001w7jn25 grid.6363.0 0000 0001 2218 4662 Computational Medicine, Berlin Institute of Health (BIH), Charite - University Medicine Berlin, Berlin, Germany
4 https://ror.org/001w7jn25 grid.6363.0 0000 0001 2218 4662 Friede Springer Cardiovascular Prevention Center@Charite, Charite - University Medicine Berlin, Berlin, Germany
5 https://ror.org/02jx3x895 grid.83440.3b 0000 0001 2190 1201 Institute of Cardiovascular Sciences, University College London, London, UK
6 grid.6363.0 0000 0001 2218 4662 Center for Digital Health, Berlin Institute of Health (BIH), Charite - University Medicine Berlin, Berlin, Germany
7 grid.5335.0 0000000121885934 MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK
8 https://ror.org/026zzn846 grid.4868.2 0000 0001 2171 1133 Precision Health University Research Institute, Queen Mary University of London and Barts NHS Trust, London, UK
9 https://ror.org/02jx3x895 grid.83440.3b 0000 0001 2190 1201 Institute of Health Informatics, University College London, London, UK
10 https://ror.org/042nb2s44 grid.116068.8 0000 0001 2341 2786 Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Massachusetts, USA
11 https://ror.org/00pd74e08 grid.5949.1 0000 0001 2172 9288 Pattern Recognition and Image Analysis Lab, University of Münster, Münster, Germany
12 grid.452924.c 0000 0001 0540 7035 British Heart Foundation Data Science Centre, London, UK
13 https://ror.org/04rtjaj74 grid.507332.0 0000 0004 9548 940X Health Data Research UK, London, UK
14 grid.454369.9 National Institute for Health Research, Biomedical Research Centre at University College London Hospitals National Institute for Health Research, Biomedical Research Centre, London, UK
15 https://ror.org/001w7jn25 grid.6363.0 0000 0001 2218 4662 Berlin Institute of Health (BIH), Charite - University Medicine Berlin, Berlin, Germany
16 https://ror.org/031t5w623 grid.452396.f 0000 0004 5937 5237 DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin Berlin, Germany
17 https://ror.org/038t36y30 grid.7700.0 0000 0001 2190 4373 Health Data Science Unit, Heidelberg University Hospital and BioQuant, Heidelberg, Germany
20 5 2024
20 5 2024
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15 425717 11 2023
3 5 2024
© The Author(s) 2024
2024
https://creativecommons.org/licenses/by/4.0/ Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Subject terms

Disease prevention
Statistics
Epidemiology
https://doi.org/10.13039/501100001659 Deutsche Forschungsgemeinschaft (German Research Foundation) Project-ID 437531118 – SFB 1470 Eils Roland We would like to acknowledge the support of the UK Biobank and the All of Us Research Program in providing access to their respective datasets. This research has been conducted using data from the UK Biobank (application number 51157) and the All of Us Research Program (by S.H. UserID 5703). Both studies have received ethical approval from their respective institutional review boards and have obtained informed consent from participants. We are grateful to the participants who generously contributed their time and data to make this research possible. This project has been funded by the Charité - Universitätsmedizin Berlin and the Einstein Foundation Berlin through the Einstein BIH Visiting Fellowship awarded to J.D. The study has been supported by the BMBF-funded Medical Informatics Initiative (HiGHmed, 01ZZ1802A - 01ZZ1802Z) and the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – Project-ID 437531118 – SFB 1470. SD is supported by a) the BHF Data Science Centre led by HDR UK (grant SP/19/3/34678), b) BigData@Heart Consortium, funded by the Innovative Medicines Initiative-2 Joint Undertaking under grant agreement 116074, c) the NIHR Biomedical Research Centre at University College London Hospital NHS Trust (UCLH BRC), d) a BHF Accelerator Award (AA/18/6/24223), e) the CVD-COVID-UK/COVID-IMPACT consortium and f) the Multimorbidity Mechanism and Therapeutic Research Collaborative (MMTRC, grant number MR/V033867/1). HH is supported by Health Data Research UK and the National Institute for Health Research, Biomedical Research Centre at University College London Hospitals.issue-copyright-statement© Springer Nature Limited 2024
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pmcThe authors have retracted this article at the request of the UK Biobank. They had used patient data from the UK Biobank study to assess risk stratification in a range of diseases; however, according to the Control of Patient Information (COPI) notice, primary care data had only been made available for research directly related to COVID-19. Therefore, this article has been retracted and the content removed.

All authors agree with this retraction.
