
==== Front
medRxiv
MEDRXIV
medRxiv
Cold Spring Harbor Laboratory

10.1101/2024.08.22.24312434
preprint
1
Article
Staphylococcus aureus Tetracycline Resistance and Co-resistance in a Doxy-PEP-Eligible Population
Mittelstaedt Rachel http://orcid.org/0000-0001-5646-1314

Kanjilal Sanjat http://orcid.org/0000-0002-1221-5725

Helekal David
Robbins Gregory K.
Grad Yonatan H.
22 8 2024
2024.08.22.24312434https://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License, which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.
http://medrxiv.org/lookup/doi/10.1101/2024.08.22.24312434
nihpp-2024.08.22.24312434.pdf
Abstract

In Staphylococcus aureus infections in men eligible for doxycycline post-exposure prophylaxis (doxy-PEP), tetracycline non-susceptibility is more prevalent than in the overall population and is associated with resistance to trimethoprim-sulfamethoxazole and clindamycin. Doxy-PEP may select for S. aureus multi-drug resistance, underscoring the importance of surveillance.
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pmc
