PMID- 10614671
OWN - NLM
STAT- MEDLINE
DCOM- 20000113
LR  - 20111117
IS  - 0013-7227 (Print)
IS  - 0013-7227 (Linking)
VI  - 141
IP  - 1
DP  - 2000 Jan
TI  - Identification, chromosomal mapping, and partial characterization of mouse InsI6:
      a new member of the insulin family.
PG  - 458-61
AB  - A new member of the mouse insulin family, InsI6, was identified from mouse
      expressed sequence tags through the use of bioinformatics. A full length cDNA was
      sequenced and predicts a protein of 191 amino acids. The protein contains a
      signal peptide and has A and B peptides as well as a connecting peptide
      consistent with the contention that it is a member of the insulin family.
      Northern analysis demonstrates that the primary site of expression is the testis,
      but message is also found in the kidney, small bowel, heart, brain and thymus.
      The gene was mapped to mouse chromosome 19 by radiation hybrid mapping. The
      chromosomal location and primary structure of this protein suggest a functional
      relationship to relaxin and relaxin-related proteins.
FAU - Kasik, J
AU  - Kasik J
AD  - Department of Pediatrics, Children's Hospital of Pittsburgh, University of
      Pittsburgh School of Medicine, PA 15213, USA.
FAU - Muglia, L
AU  - Muglia L
FAU - Stephan, D A
AU  - Stephan DA
FAU - Menon, R K
AU  - Menon RK
LA  - eng
GR  - DK49845/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Endocrinology
JT  - Endocrinology
JID - 0375040
RN  - 0 (DNA, Complementary)
RN  - 0 (Insulin)
RN  - 0 (RNA, Messenger)
SB  - AIM
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Blotting, Northern
MH  - Chromosome Mapping
MH  - DNA, Complementary/analysis/genetics
MH  - Gene Amplification
MH  - Humans
MH  - Insulin/*genetics/metabolism
MH  - Mice
MH  - Molecular Sequence Data
MH  - RNA, Messenger/biosynthesis/genetics
MH  - Rats
EDAT- 1999/12/30 00:00
MHDA- 1999/12/30 00:01
CRDT- 1999/12/30 00:00
PHST- 1999/12/30 00:00 [pubmed]
PHST- 1999/12/30 00:01 [medline]
PHST- 1999/12/30 00:00 [entrez]
AID - 10.1210/endo.141.1.7376 [doi]
PST - ppublish
SO  - Endocrinology. 2000 Jan;141(1):458-61. doi: 10.1210/endo.141.1.7376.