PMID- 10585774
OWN - NLM
STAT- MEDLINE
DCOM- 20000204
LR  - 20071115
IS  - 0888-7543 (Print)
IS  - 0888-7543 (Linking)
VI  - 62
IP  - 1
DP  - 1999 Nov 15
TI  - Cloning and mapping of a novel human serum/glucocorticoid regulated kinase-like
      gene, SGKL, to chromosome 8q12.3-q13.1.
PG  - 95-7
AB  - Serum/glucocorticoid regulated kinase (sgk) belongs to a newly emerging subfamily
      of the serine/threonine protein kinase family. Although human SGK shares 98%
      amino acid identity with rat sgk, their expression levels are regulated
      differently, which indicates the existence of other SGKs in humans. In this
      paper, we reported the cloning of human SGKL, which encodes a protein sharing 67 
      and 66% amino acid identity with rat sgk and human SGK, respectively. A 4.4-kb
      transcript of human SGKL was detected in 16 human tissues examined and was found 
      to be most abundant in lung. By radiation hybrid mapping, the SGKL gene was
      located to human chromosome 8q12. 1-q13.1 between markers D8S510 and D8S1797.
CI  - Copyright 1999 Academic Press.
FAU - Dai, F
AU  - Dai F
AD  - Institute of Genetics, Fudan University, 220 Handan Road, Shanghai, 200433,
      People's Republic of China.
FAU - Yu, L
AU  - Yu L
FAU - He, H
AU  - He H
FAU - Zhao, Y
AU  - Zhao Y
FAU - Yang, J
AU  - Yang J
FAU - Zhang, X
AU  - Zhang X
FAU - Zhao, S
AU  - Zhao S
LA  - eng
SI  - GENBANK/AF085233
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Genomics
JT  - Genomics
JID - 8800135
RN  - 0 (Helminth Proteins)
RN  - 9002-60-2 (Adrenocorticotropic Hormone)
RN  - EC 2.7.11.1 (Protein-Serine-Threonine Kinases)
RN  - EC 2.7.11.1 (SGK3 protein, human)
SB  - IM
MH  - Adrenocorticotropic Hormone/deficiency
MH  - Amino Acid Sequence
MH  - Animals
MH  - Blotting, Northern
MH  - Caenorhabditis elegans/genetics
MH  - Chromosome Mapping
MH  - Chromosomes, Human, Pair 8/*genetics
MH  - Cloning, Molecular
MH  - Dogfish/genetics
MH  - Expressed Sequence Tags
MH  - *Genes
MH  - Helminth Proteins/genetics
MH  - Humans
MH  - Lod Score
MH  - Molecular Sequence Data
MH  - Organ Specificity
MH  - Protein-Serine-Threonine Kinases/biosynthesis/*genetics
MH  - Rats
MH  - Sequence Alignment
MH  - Sequence Homology, Amino Acid
MH  - Species Specificity
MH  - Xenopus laevis/genetics
EDAT- 1999/12/10 00:00
MHDA- 1999/12/10 00:01
CRDT- 1999/12/10 00:00
PHST- 1999/12/10 00:00 [pubmed]
PHST- 1999/12/10 00:01 [medline]
PHST- 1999/12/10 00:00 [entrez]
AID - 10.1006/geno.1999.5969 [doi]
AID - S0888-7543(99)95969-4 [pii]
PST - ppublish
SO  - Genomics. 1999 Nov 15;62(1):95-7. doi: 10.1006/geno.1999.5969.