PMID- 10580403
OWN - NLM
STAT- MEDLINE
DCOM- 19991217
LR  - 20061115
IS  - 0889-2229 (Print)
IS  - 0889-2229 (Linking)
VI  - 15
IP  - 17
DP  - 1999 Nov 20
TI  - Phylogeny of a novel family of human endogenous retrovirus sequences, HERV-W, in 
      humans and other primates.
PG  - 1529-33
AB  - A novel human endogenous retrovirus, HERV-W, has been characterized on the basis 
      of multiple sclerosis-associated retrovirus (MSRV) probes. We have analyzed the
      phylogenetic distribution of HERV-W in humans and other primate species. As
      HERV-W presents a C/D chimeric nature and is largely composed of deleted
      elements, Southern blots were performed using gag, pol, env, and LTR probes. The 
      relative complexities observed for gag, pol, env, and LTR regions were similar in
      humans, apes, and Old World monkeys, the minimal number of bands observed after
      Southern blot analysis being 25, 50, 10, and at least 100, respectively. The
      HERV-W family entered the genome of catarrhines more than 25 million years ago.
FAU - Voisset, C
AU  - Voisset C
AD  - Unite Mixte de Recherche 103 CNRS-bioMerieux, Ecole Normale Superieure de Lyon,
      France.
FAU - Blancher, A
AU  - Blancher A
FAU - Perron, H
AU  - Perron H
FAU - Mandrand, B
AU  - Mandrand B
FAU - Mallet, F
AU  - Mallet F
FAU - Paranhos-Baccala, G
AU  - Paranhos-Baccala G
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - AIDS Res Hum Retroviruses
JT  - AIDS research and human retroviruses
JID - 8709376
RN  - 0 (DNA Probes)
RN  - 0 (Gene Products, env)
RN  - 0 (Gene Products, gag)
RN  - 0 (Gene Products, pol)
RN  - 0 (RNA, Viral)
SB  - IM
SB  - X
MH  - Animals
MH  - Base Sequence
MH  - Blotting, Southern/veterinary
MH  - DNA Probes/genetics
MH  - Endogenous Retroviruses/*classification/genetics
MH  - Gene Products, env/genetics
MH  - Gene Products, gag/genetics
MH  - Gene Products, pol/genetics
MH  - Genome, Viral
MH  - Humans
MH  - Molecular Sequence Data
MH  - *Phylogeny
MH  - Primates/*virology
MH  - RNA, Viral/analysis
MH  - Terminal Repeat Sequences/genetics
EDAT- 1999/12/02 00:00
MHDA- 1999/12/02 00:01
CRDT- 1999/12/02 00:00
PHST- 1999/12/02 00:00 [pubmed]
PHST- 1999/12/02 00:01 [medline]
PHST- 1999/12/02 00:00 [entrez]
AID - 10.1089/088922299309810 [doi]
PST - ppublish
SO  - AIDS Res Hum Retroviruses. 1999 Nov 20;15(17):1529-33. doi:
      10.1089/088922299309810.