PMID- 10580072 OWN - NLM STAT- MEDLINE DCOM- 19991202 LR - 20131121 IS - 0028-4793 (Print) IS - 0028-4793 (Linking) VI - 341 IP - 23 DP - 1999 Dec 2 TI - Leydig-cell tumors caused by an activating mutation of the gene encoding the luteinizing hormone receptor. PG - 1731-6 FAU - Liu, G AU - Liu G AD - Department of Pediatrics, Northwestern University Medical School and Children's Memorial Institute for Education and Research, Chicago, IL 60614, USA. FAU - Duranteau, L AU - Duranteau L FAU - Carel, J C AU - Carel JC FAU - Monroe, J AU - Monroe J FAU - Doyle, D A AU - Doyle DA FAU - Shenker, A AU - Shenker A LA - eng GR - 5T32-DK07169-19A1/DK/NIDDK NIH HHS/United States PT - Case Reports PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - N Engl J Med JT - The New England journal of medicine JID - 0255562 RN - 0 (Inositol Phosphates) RN - 0 (Receptors, LH) RN - E0399OZS9N (Cyclic AMP) SB - IM CIN - N Engl J Med. 1999 Dec 2;341(23):1763-5. PMID: 10580079 MH - Child MH - Cyclic AMP/biosynthesis MH - Humans MH - Inositol Phosphates/biosynthesis MH - Leydig Cell Tumor/complications/*genetics/pathology MH - Male MH - Mutation MH - Puberty, Precocious/*etiology MH - Receptors, LH/*genetics/metabolism MH - Testicular Neoplasms/complications/*genetics/pathology MH - Testis/pathology EDAT- 1999/12/02 00:00 MHDA- 1999/12/02 00:01 CRDT- 1999/12/02 00:00 PHST- 1999/12/02 00:00 [pubmed] PHST- 1999/12/02 00:01 [medline] PHST- 1999/12/02 00:00 [entrez] AID - 10.1056/NEJM199912023412304 [doi] PST - ppublish SO - N Engl J Med. 1999 Dec 2;341(23):1731-6. doi: 10.1056/NEJM199912023412304.