PMID- 10570973
OWN - NLM
STAT- MEDLINE
DCOM- 19991202
LR  - 20200409
IS  - 0378-1119 (Print)
IS  - 0378-1119 (Linking)
VI  - 238
IP  - 2
DP  - 1999 Oct 1
TI  - Cloning and characterization of a putative mouse acetyl-CoA transporter cDNA.
PG  - 455-62
AB  - A mouse acetyl-CoA transporter (Acatn) cDNA was isolated by PCR cloning. Mouse
      Acatn exhibited 92% homology with human sequence on the basis of amino-acid
      sequence. The predicted gene product of Acatn is a 61 kDa hydrophobic protein
      with six to 10 transmembrane domains. Transfection of mouse Acatn cDNA into
      HeLa/GT3+ cells resulted in significant increase in the amount of 9-O-acetylated 
      gangliosides, suggesting that Acatn does play an important role in the
      acetylation of gangliosides. Northern blot analysis of Acatn mRNA suggested that 
      transcript of Acatn is widely distributed in various adult tissues. Expression of
      Acatn was found to be developmentally regulated, with high expression levels
      during early embryonic stages, and then there was a subsequent decrease in
      expression levels in the later embryonic stages.
FAU - Bora, R S
AU  - Bora RS
AD  - Laboratory for Cellular Glycobiology, Frontier Research Program, The Institute of
      Physical and Chemical Research, Wako, Saitama, Japan.
FAU - Kanamori, A
AU  - Kanamori A
FAU - Hirabayashi, Y
AU  - Hirabayashi Y
LA  - eng
SI  - GENBANK/AB016795
SI  - GENBANK/AB037362
SI  - GENBANK/AB037363
SI  - GENBANK/AB037364
SI  - GENBANK/AB037365
SI  - GENBANK/AB037366
SI  - GENBANK/AB037367
SI  - GENBANK/AB037368
SI  - GENBANK/AB039326
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Gene
JT  - Gene
JID - 7706761
RN  - 0 (Carrier Proteins)
RN  - 0 (DNA, Complementary)
RN  - 0 (Gangliosides)
RN  - 0 (Membrane Proteins)
RN  - 0 (Membrane Transport Proteins)
RN  - 0 (RNA, Messenger)
RN  - 0 (SLC33A1 protein, human)
RN  - 0 (Slc33a1 protein, mouse)
SB  - IM
MH  - Acetylation
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Carrier Proteins/*genetics
MH  - Cloning, Molecular
MH  - DNA, Complementary
MH  - Embryonic and Fetal Development/genetics
MH  - Gangliosides/metabolism
MH  - Gene Expression Regulation, Developmental
MH  - HeLa Cells
MH  - Humans
MH  - Membrane Proteins/*genetics
MH  - *Membrane Transport Proteins
MH  - Mice
MH  - Molecular Sequence Data
MH  - Polymerase Chain Reaction
MH  - RNA, Messenger/genetics/metabolism
MH  - Sequence Homology, Amino Acid
PMC - PMC7127759
EDAT- 1999/11/26 00:00
MHDA- 1999/11/26 00:01
CRDT- 1999/11/26 00:00
PHST- 1999/11/26 00:00 [pubmed]
PHST- 1999/11/26 00:01 [medline]
PHST- 1999/11/26 00:00 [entrez]
AID - S0378111999003613 [pii]
AID - 10.1016/s0378-1119(99)00361-3 [doi]
PST - ppublish
SO  - Gene. 1999 Oct 1;238(2):455-62. doi: 10.1016/s0378-1119(99)00361-3.