PMID- 10570243
OWN - NLM
STAT- MEDLINE
DCOM- 19991230
LR  - 20190610
IS  - 0006-3002 (Print)
IS  - 0006-3002 (Linking)
VI  - 1441
IP  - 2-3
DP  - 1999 Nov 23
TI  - Acyl-coenzyme A binding protein (ACBP).
PG  - 150-61
AB  - Acyl-coenzyme A binding proteins are known from a large group of eukaryote
      species and to bind a long chain length acyl-CoA ester with very high affinity.
      Detailed biochemical mapping of ligand binding properties has been obtained as
      well as in-depth structural studies on the bovine apo-protein and of the complex 
      with palmitoyl-CoA using NMR spectroscopy. In the four alpha-helix bundle
      structure, a set of 21 highly conserved residues present in more that 90% of all 
      known sequences of acyl-coenzyme A binding proteins constitutes three separate
      mini-cores. These residues are predominantly located at the helix-helix
      interfaces. From studies of a large set of mutant proteins the role of the
      conserved residues has been related to structure, function, folding and
      stability.
FAU - Kragelund, B B
AU  - Kragelund BB
AD  - Carlsberg Laboratory, Department of Chemistry, Gl. Carlsberg Vej 10, DK-2500,
      Valby, Denmark.
FAU - Knudsen, J
AU  - Knudsen J
FAU - Poulsen, F M
AU  - Poulsen FM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - Netherlands
TA  - Biochim Biophys Acta
JT  - Biochimica et biophysica acta
JID - 0217513
RN  - 0 (Carrier Proteins)
RN  - 0 (Diazepam Binding Inhibitor)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - *Carrier Proteins/chemistry/genetics/metabolism
MH  - Diazepam Binding Inhibitor
MH  - Humans
MH  - Models, Molecular
MH  - Molecular Sequence Data
MH  - Molecular Structure
MH  - Mutagenesis
MH  - Sequence Alignment
RF  - 31
EDAT- 1999/11/26 00:00
MHDA- 1999/11/26 00:01
CRDT- 1999/11/26 00:00
PHST- 1999/11/26 00:00 [pubmed]
PHST- 1999/11/26 00:01 [medline]
PHST- 1999/11/26 00:00 [entrez]
AID - S1388-1981(99)00151-1 [pii]
AID - 10.1016/s1388-1981(99)00151-1 [doi]
PST - ppublish
SO  - Biochim Biophys Acta. 1999 Nov 23;1441(2-3):150-61. doi:
      10.1016/s1388-1981(99)00151-1.