PMID- 10564808
OWN - NLM
STAT- MEDLINE
DCOM- 20000111
LR  - 20190707
IS  - 0378-1119 (Print)
IS  - 0378-1119 (Linking)
VI  - 240
IP  - 1
DP  - 1999 Nov 15
TI  - Characterization of the mouse Kid1 gene and identification of a highly related
      gene, Kid2.
PG  - 13-22
AB  - Kid1 encodes a zinc finger protein that has been implicated in renal cell
      differentiation. Levels of Kid1 mRNA correlate with maturation of kidney tubule
      epithelia in rat post-natal kidney development and during kidney regeneration
      following injury. KID1 is a putative transcriptional repressor, containing a KRAB
      domain at its amino terminus that mediates transcriptional repression in
      transient cell transfection assays when fused to a heterologous DNA-binding
      domain. In this paper, we describe the isolation and characterization of the
      mouse homologue of Kid1 and the identification of a novel highly related mouse
      gene, Kid2, Kid1 and Kid2 are tightly linked on mouse chromosome 11 and show
      conservation across mammals. Both genes are expressed predominantly in the mouse 
      adult kidney and brain, but transcripts are also detected in embryonic brain,
      kidney, gut and lung, suggesting an additional role for these genes during mouse 
      development.
FAU - Tekki-Kessaris, N
AU  - Tekki-Kessaris N
AD  - University of Cambridge, Department of Genetics, Downing Street, Cambridge, UK.
FAU - Bonventre, J V
AU  - Bonventre JV
FAU - Boulter, C A
AU  - Boulter CA
LA  - eng
SI  - GENBANK/AF184111
SI  - GENBANK/AF184112
GR  - DK 39773/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Gene
JT  - Gene
JID - 7706761
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (RNA, Messenger)
RN  - 0 (Transcription Factors)
RN  - 0 (ZNF354A protein, human)
RN  - 0 (Zfp354a protein, mouse)
RN  - 0 (Zfp354b protein, mouse)
RN  - 0 (Znf354a protein, rat)
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Cats
MH  - Chromosome Mapping
MH  - Conserved Sequence
MH  - DNA/chemistry/genetics/isolation & purification
MH  - DNA-Binding Proteins/*genetics
MH  - Embryo, Mammalian/metabolism
MH  - Gene Expression Regulation, Developmental
MH  - Genes/*genetics
MH  - Haplorhini
MH  - Humans
MH  - Male
MH  - Mammals/genetics
MH  - Mice
MH  - Mice, Inbred Strains
MH  - Molecular Sequence Data
MH  - RNA, Messenger/genetics/metabolism
MH  - Rats
MH  - Sequence Alignment
MH  - Sequence Analysis, DNA
MH  - Sequence Homology, Amino Acid
MH  - Sheep
MH  - Tissue Distribution
MH  - Transcription Factors/*genetics
MH  - Zinc Fingers/genetics
EDAT- 1999/11/24 00:00
MHDA- 1999/11/24 00:01
CRDT- 1999/11/24 00:00
PHST- 1999/11/24 00:00 [pubmed]
PHST- 1999/11/24 00:01 [medline]
PHST- 1999/11/24 00:00 [entrez]
AID - S0378-1119(99)00440-0 [pii]
AID - 10.1016/s0378-1119(99)00440-0 [doi]
PST - ppublish
SO  - Gene. 1999 Nov 15;240(1):13-22. doi: 10.1016/s0378-1119(99)00440-0.