PMID- 10556532
OWN - NLM
STAT- MEDLINE
DCOM- 19991222
LR  - 20191210
IS  - 0014-5793 (Print)
IS  - 0014-5793 (Linking)
VI  - 460
IP  - 3
DP  - 1999 Nov 5
TI  - Molecular cloning of a novel CC chemokine, interleukin-11 receptor alpha-locus
      chemokine (ILC), which is located on chromosome 9p13 and a potential homologue of
      a CC chemokine encoded by molluscum contagiosum virus.
PG  - 544-8
AB  - Molluscum contagiosum virus (MCV) encodes a CC chemokine MC148R which is likely
      to have been acquired from the host. By a homology search employing MC148R as a
      probe, we have identified a novel CC chemokine whose gene exists next to the
      IL-11 receptor alpha (IL-11Ralpha) gene in both humans and mice. Thus, this
      chemokine maps to chromosome 9p13 in humans where IL-11Ralpha has been assigned. 
      We term this novel chemokine IL-11Ralpha-locus chemokine (ILC). ILC has the
      highest homology to MC148R among the known human CC chemokines. Furthermore, ILC 
      is strongly and selectively expressed in the skin where infection of MCV also
      takes place. Thus, ILC is likely to be the original chemokine of MC148R.
FAU - Ishikawa-Mochizuki, I
AU  - Ishikawa-Mochizuki I
AD  - Shionogi Institute for Medical Science, Osaka, Japan.
FAU - Kitaura, M
AU  - Kitaura M
FAU - Baba, M
AU  - Baba M
FAU - Nakayama, T
AU  - Nakayama T
FAU - Izawa, D
AU  - Izawa D
FAU - Imai, T
AU  - Imai T
FAU - Yamada, H
AU  - Yamada H
FAU - Hieshima, K
AU  - Hieshima K
FAU - Suzuki, R
AU  - Suzuki R
FAU - Nomiyama, H
AU  - Nomiyama H
FAU - Yoshie, O
AU  - Yoshie O
LA  - eng
SI  - GENBANK/AB010445
SI  - GENBANK/AB013398
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - FEBS Lett
JT  - FEBS letters
JID - 0155157
RN  - 0 (CCL27 protein, human)
RN  - 0 (Ccl27a protein, mouse)
RN  - 0 (Chemokine CCL27)
RN  - 0 (Chemokines, CC)
RN  - 0 (DNA, Complementary)
RN  - 0 (IL11RA protein, human)
RN  - 0 (Il11ra1 protein, mouse)
RN  - 0 (Il11ra2 protein, mouse)
RN  - 0 (Interleukin-11)
RN  - 0 (Interleukin-11 Receptor alpha Subunit)
RN  - 0 (Receptors, Interleukin)
RN  - 0 (Receptors, Interleukin-11)
RN  - 0 (Recombinant Proteins)
RN  - 0 (Viral Proteins)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Chemokine CCL27
MH  - Chemokines, CC/biosynthesis/*genetics/isolation & purification
MH  - Chromosomes, Human, Pair 9/*genetics
MH  - Cloning, Molecular
MH  - DNA, Complementary/isolation & purification
MH  - Humans
MH  - Interleukin-11/*metabolism
MH  - Interleukin-11 Receptor alpha Subunit
MH  - Mice
MH  - Molecular Sequence Data
MH  - Molluscum contagiosum virus/*genetics
MH  - Organ Specificity/genetics
MH  - Receptors, Interleukin/*metabolism
MH  - Receptors, Interleukin-11
MH  - Recombinant Proteins/biosynthesis/chemistry/pharmacology
MH  - Sequence Alignment
MH  - *Sequence Homology, Amino Acid
MH  - Viral Proteins/*genetics
EDAT- 1999/11/11 00:00
MHDA- 1999/11/11 00:01
CRDT- 1999/11/11 00:00
PHST- 1999/11/11 00:00 [pubmed]
PHST- 1999/11/11 00:01 [medline]
PHST- 1999/11/11 00:00 [entrez]
AID - S0014-5793(99)01406-4 [pii]
AID - 10.1016/s0014-5793(99)01406-4 [doi]
PST - ppublish
SO  - FEBS Lett. 1999 Nov 5;460(3):544-8. doi: 10.1016/s0014-5793(99)01406-4.