PMID- 10556517
OWN - NLM
STAT- MEDLINE
DCOM- 19991222
LR  - 20190621
IS  - 0014-5793 (Print)
IS  - 0014-5793 (Linking)
VI  - 460
IP  - 3
DP  - 1999 Nov 5
TI  - Cloning and characterization of B delta, a novel regulatory subunit of protein
      phosphatase 2A.
PG  - 462-6
AB  - Variable regulatory subunits of protein phosphatase 2A (PP2A) modulate activity, 
      substrate selectivity and subcellular targeting of the enzyme. We have cloned a
      novel member of the B type regulatory subunit family, B delta, which is most
      highly related to B alpha. B delta shares with B alpha epitopes previously used
      to generate subunit-specific antibodies. Like B alpha, but unlike B beta and B
      gamma which are highly brain-enriched, B delta mRNA and protein expression in
      tissues is widespread. B delta is a cytosolic subunit of PP2A with a subcellular 
      localization different from B alpha and may therefore target a pool of PP2A
      holoenzymes to specific substrates.
FAU - Strack, S
AU  - Strack S
AD  - Department of Molecular Physiology and Biophysics, Vanderbilt University Medical 
      Center, Nashville, TN 37232, USA.
FAU - Chang, D
AU  - Chang D
FAU - Zaucha, J A
AU  - Zaucha JA
FAU - Colbran, R J
AU  - Colbran RJ
FAU - Wadzinski, B E
AU  - Wadzinski BE
LA  - eng
SI  - GENBANK/AF180350
GR  - CA68485/CA/NCI NIH HHS/United States
GR  - GM47973/GM/NIGMS NIH HHS/United States
GR  - GM51366/GM/NIGMS NIH HHS/United States
GR  - etc.
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - England
TA  - FEBS Lett
JT  - FEBS letters
JID - 0155157
RN  - 0 (Peptide Fragments)
RN  - 0 (RNA, Messenger)
RN  - EC 3.1.3.16 (Phosphoprotein Phosphatases)
RN  - EC 3.1.3.16 (Protein Phosphatase 2)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Brain/enzymology
MH  - COS Cells
MH  - Cell Membrane/enzymology
MH  - Cloning, Molecular
MH  - Cytosol/enzymology
MH  - Molecular Sequence Data
MH  - Organ Specificity/genetics
MH  - Peptide Fragments/biosynthesis/chemistry/*genetics
MH  - Phosphoprotein Phosphatases/biosynthesis/*chemistry/*genetics
MH  - Protein Phosphatase 2
MH  - RNA, Messenger/biosynthesis
MH  - Rats
MH  - Signal Transduction
EDAT- 1999/11/11 00:00
MHDA- 1999/11/11 00:01
CRDT- 1999/11/11 00:00
PHST- 1999/11/11 00:00 [pubmed]
PHST- 1999/11/11 00:01 [medline]
PHST- 1999/11/11 00:00 [entrez]
AID - S0014-5793(99)01377-0 [pii]
AID - 10.1016/s0014-5793(99)01377-0 [doi]
PST - ppublish
SO  - FEBS Lett. 1999 Nov 5;460(3):462-6. doi: 10.1016/s0014-5793(99)01377-0.