PMID- 10548410
OWN - NLM
STAT- MEDLINE
DCOM- 19991206
LR  - 20190701
IS  - 0304-3940 (Print)
IS  - 0304-3940 (Linking)
VI  - 274
IP  - 3
DP  - 1999 Oct 29
TI  - Structure and alternative splicing of the gene encoding alpha1G, a human brain T 
      calcium channel alpha1 subunit.
PG  - 143-6
AB  - The structure of CACNA1G, the gene encoding alpha1G, a human brain T Ca2+ channel
      alpha1 subunit, was determined by comparison of polymerase chain
      reaction-amplified brain cDNA and genomic sequences. The gene consists of at
      least 38 exons, two of them newly-identified, spanning at least 66490 basepairs
      of chromosome 17q22. Alternative splicing of the RNA occurs at six sites:
      cassette exons 14, 26, 34 and 35, an internal donor in exon 25 and protein-coding
      intron 38B. Additionally, the RNA can be polyadenylated at either of two sites.
      Alternative splicing of CACNA1G RNA may lead to expression of as many as 24
      distinct protein products, ranging from 2171 to 2377 amino-acids residues.
FAU - Mittman, S
AU  - Mittman S
AD  - Department of Anesthesiology, The Johns Hopkins University School of Medicine,
      Baltimore, MD 21287, USA. smittman@jhmi.edu
FAU - Guo, J
AU  - Guo J
FAU - Agnew, W S
AU  - Agnew WS
LA  - eng
SI  - GENBANK/AF134985
SI  - GENBANK/AF134986
GR  - K08NS01939/NS/NINDS NIH HHS/United States
GR  - P50HL52307/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
RN  - 0 (Calcium Channels, T-Type)
SB  - IM
MH  - Alternative Splicing/*genetics
MH  - Brain Chemistry/*genetics
MH  - Calcium Channels, T-Type/chemistry/*genetics
MH  - Chromosome Mapping
MH  - Exons/genetics
MH  - Gene Expression Regulation
MH  - Humans
MH  - Molecular Sequence Data
MH  - Protein Structure, Tertiary
EDAT- 1999/11/05 00:00
MHDA- 1999/11/05 00:01
CRDT- 1999/11/05 00:00
PHST- 1999/11/05 00:00 [pubmed]
PHST- 1999/11/05 00:01 [medline]
PHST- 1999/11/05 00:00 [entrez]
AID - S0304394099007168 [pii]
AID - 10.1016/s0304-3940(99)00716-8 [doi]
PST - ppublish
SO  - Neurosci Lett. 1999 Oct 29;274(3):143-6. doi: 10.1016/s0304-3940(99)00716-8.