PMID- 10543404
OWN - NLM
STAT- MEDLINE
DCOM- 19991110
LR  - 20190722
IS  - 0340-6717 (Print)
IS  - 0340-6717 (Linking)
VI  - 105
IP  - 4
DP  - 1999 Oct
TI  - Chromosomal localization of three human poly(A)-binding protein genes and four
      related pseudogenes.
PG  - 347-53
AB  - In humans, the poly(A)-binding proteins (PABPs) comprise a small nuclear isoform 
      and a conserved gene family that displays at least three functional proteins:
      PABP1, inducible PABP (iPABP), and PABP3, plus four pseudogenes (1, 2, 3, and
      PABP4). In situ hybridization of PABP3 cDNA as the probe on metaphasic
      chromosomes have revealed five possible loci for this gene family at 2q21-q22,
      13q11-q12, 12q13.3-q15, 8q22, and 3q24-q25. Amplifications of specific DNA
      fragments from a human-rodent somatic cell hybrid panel have allowed us to
      associate PABP1 and PABP3 with 8q22 and 13q11-q12, respectively. The iPABP gene
      has been assigned to chromosome 1. This result, compared with radiation hybrid
      database information, strengthens the location of this gene to 1p32-p36. The
      pseudogenes PABP4, 1, and 2 have been assigned to chromosomes 15, 4, and 14,
      respectively. Three loci detected on chromosome spreads are not associated with
      any amplified fragment. They might represent other related PABP genes not yet
      identified.
FAU - Feral, C
AU  - Feral C
AD  - Unite INSERM U99, Hopital H Mondor, Creteil, France.
FAU - Mattei, M G
AU  - Mattei MG
FAU - Pawlak, A
AU  - Pawlak A
FAU - Guellaen, G
AU  - Guellaen G
LA  - eng
SI  - GENBANK/G49185
SI  - GENBANK/G49186
SI  - GENBANK/G49187
SI  - GENBANK/G49188
SI  - GENBANK/G49189
SI  - GENBANK/G49190
SI  - GENBANK/G49191
SI  - GENBANK/U60801
SI  - GENBANK/U63542
SI  - GENBANK/U64661
SI  - GENBANK/U64662
SI  - GENBANK/Z48501
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Hum Genet
JT  - Human genetics
JID - 7613873
RN  - 0 (DNA Primers)
RN  - 0 (Poly(A)-Binding Proteins)
RN  - 0 (RNA-Binding Proteins)
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Blotting, Southern
MH  - Chromosome Mapping
MH  - Chromosomes, Human/genetics
MH  - DNA/genetics
MH  - DNA Primers/genetics
MH  - Humans
MH  - Hybrid Cells
MH  - In Situ Hybridization
MH  - Molecular Sequence Data
MH  - *Multigene Family
MH  - Poly(A)-Binding Proteins
MH  - Polymerase Chain Reaction
MH  - *Pseudogenes
MH  - RNA-Binding Proteins/*genetics
PMC - PMC1865476
MID - HALMS56829
OID - NLM: HALMS56829
EDAT- 1999/10/30 00:00
MHDA- 1999/10/30 00:01
CRDT- 1999/10/30 00:00
PHST- 1999/10/30 00:00 [pubmed]
PHST- 1999/10/30 00:01 [medline]
PHST- 1999/10/30 00:00 [entrez]
AID - 10.1007/s004399900148 [doi]
PST - ppublish
SO  - Hum Genet. 1999 Oct;105(4):347-53. doi: 10.1007/s004399900148.