PMID- 10542397
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 1879-3061 (Electronic)
IS  - 1043-2760 (Linking)
VI  - 10
IP  - 10
DP  - 1999 Dec
TI  - Multimeric Coactivator Complexes for Steroid/Nuclear Receptors.
PG  - 403-407
AB  - Nuclear receptors regulate transcription in direct response to their cognate
      hormonal ligands. Ligand binding leads to the dissociation of corepressors and
      the recruitment of coactivators. Many of these factors, acting in large
      complexes, have emerged as chromatin remodelers through intrinsic
      histone-modifying activities or through other novel functions. In addition, other
      ligand-recruited complexes appear to act more directly on the transcriptional
      apparatus, suggesting that transcriptional regulation by nuclear receptors might 
      involve a process of both chromatin alterations and direct recruitment of key
      initiation components at regulated promoters.
FAU - Freedman
AU  - Freedman LP
AD  - Cell Biology Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue,
      New York, NY 10021, USA.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Trends Endocrinol Metab
JT  - Trends in endocrinology and metabolism: TEM
JID - 9001516
EDAT- 1999/11/05 00:00
MHDA- 1999/11/05 00:01
CRDT- 1999/11/05 00:00
PHST- 1999/11/05 00:00 [pubmed]
PHST- 1999/11/05 00:01 [medline]
PHST- 1999/11/05 00:00 [entrez]
AID - S1043-2760(99)00208-8 [pii]
AID - 10.1016/s1043-2760(99)00208-8 [doi]
PST - ppublish
SO  - Trends Endocrinol Metab. 1999 Dec;10(10):403-407. doi:
      10.1016/s1043-2760(99)00208-8.