PMID- 10542331
OWN - NLM
STAT- MEDLINE
DCOM- 19991208
LR  - 20190610
IS  - 0006-3002 (Print)
IS  - 0006-3002 (Linking)
VI  - 1447
IP  - 2-3
DP  - 1999 Oct 28
TI  - Identification of the true human orthologue of the mouse Zp1 gene: evidence for
      greater complexity in the mammalian zona pellucida?
PG  - 303-6
AB  - The mammalian zona pellucida is a mixture of glycoproteins, believed to be
      encoded by three distinct genes, ZP1/ZPB, ZP2/ZPA, and ZP3/ZPC. We have now
      determined that the true human orthologue of the mouse Zp1 gene is not ZPB, but
      that there is a distinct human ZP1 gene. Comparison of the human ZP1 and murine
      Zp1 genes indicates significant conservation of nucleotide and amino acid
      sequences, of intron-exon size and organisation, and of regulatory sequences. In 
      addition, the mouse and human ZP1 genes are in a region of conserved synteny
      between human chromosome 11 and mouse chromosome 19.
FAU - Hughes, D C
AU  - Hughes DC
AD  - Reproductive Biology and Genetics Group, Assisted Conception Unit, Birmingham
      Women's Hospital, Birmingham, UK. dhughes@hgmp.mrc.ac.uk
FAU - Barratt, C L
AU  - Barratt CL
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Biochim Biophys Acta
JT  - Biochimica et biophysica acta
JID - 0217513
RN  - 0 (Egg Proteins)
RN  - 0 (Membrane Glycoproteins)
RN  - 0 (Receptors, Cell Surface)
RN  - 0 (ZP1 protein, human)
RN  - 0 (ZP2 protein, human)
RN  - 0 (ZP3 protein, human)
RN  - 0 (Zona Pellucida Glycoproteins)
RN  - 0 (Zp1 protein, mouse)
RN  - 0 (Zp2 protein, mouse)
RN  - 0 (Zp3 protein, mouse)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Chromosome Mapping
MH  - *Chromosomes, Human, Pair 11
MH  - Egg Proteins/*genetics/metabolism
MH  - Female
MH  - Humans
MH  - Membrane Glycoproteins/*genetics/metabolism
MH  - Mice
MH  - Molecular Sequence Data
MH  - *Receptors, Cell Surface
MH  - Sequence Alignment
MH  - Sequence Analysis, DNA
MH  - Zona Pellucida/*metabolism
MH  - Zona Pellucida Glycoproteins
EDAT- 1999/11/05 00:00
MHDA- 1999/11/05 00:01
CRDT- 1999/11/05 00:00
PHST- 1999/11/05 00:00 [pubmed]
PHST- 1999/11/05 00:01 [medline]
PHST- 1999/11/05 00:00 [entrez]
AID - S0167-4781(99)00181-5 [pii]
AID - 10.1016/s0167-4781(99)00181-5 [doi]
PST - ppublish
SO  - Biochim Biophys Acta. 1999 Oct 28;1447(2-3):303-6. doi:
      10.1016/s0167-4781(99)00181-5.