PMID- 10537137
OWN - NLM
STAT- MEDLINE
DCOM- 19991122
LR  - 20191210
IS  - 0013-7227 (Print)
IS  - 0013-7227 (Linking)
VI  - 140
IP  - 11
DP  - 1999 Nov
TI  - Prolactin (PRL)-like protein J, a novel member of the PRL/growth hormone family, 
      is exclusively expressed in maternal decidua.
PG  - 5095-101
AB  - A search of a nonmouse, nonhuman, expressed sequence tag database for messenger
      RNAs in the PRL/GH family has identified a novel rat complementary DNA clone. The
      encoded protein, designated PRL-like protein J (PLP-J), is predicted to be
      synthesized as a precursor of 211 amino acids, modified by N-linked
      glycosylation, and secreted as a mature glycoprotein of 182 residues. PLP-J
      messenger RNA synthesis is limited to early pregnancy with abundant expression on
      day 7, slightly declining expression on day 9, and no detectable expression by
      day 11. Unlike most other PRL family members, PLP-J does not appear to be
      synthesized by placental trophoblasts but, rather, by decidual cells surrounding 
      the implantation site. By sequence similarity to rat PLP-J, a murine clone was
      identified in a mouse expressed sequence tag database. Mouse PLP-J was used to
      map the gene to a 700-kb region of mouse chromosome 13 that includes other
      members of the PRL/GH family.
FAU - Toft, D J
AU  - Toft DJ
AD  - Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern
      University, Evanston, Illinois 60208, USA.
FAU - Linzer, D I
AU  - Linzer DI
LA  - eng
SI  - GENBANK/AF150740
SI  - GENBANK/AF150741
GR  - HD-24518/HD/NICHD NIH HHS/United States
GR  - HD-29962/HD/NICHD NIH HHS/United States
GR  - P30 HD-28048/HD/NICHD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Endocrinology
JT  - Endocrinology
JID - 0375040
RN  - 0 (DNA, Complementary)
RN  - 0 (Glycoproteins)
RN  - 0 (Intercellular Signaling Peptides and Proteins)
RN  - 0 (Prlpi protein, mouse)
RN  - 0 (Prlpi protein, rat)
RN  - 9002-62-4 (Prolactin)
SB  - AIM
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Chromosome Mapping
MH  - Chromosomes, Artificial, Yeast
MH  - DNA, Complementary/chemistry
MH  - Decidua/*metabolism
MH  - Embryo Implantation
MH  - Female
MH  - *Gene Expression
MH  - Gestational Age
MH  - Glycoproteins/chemistry/*genetics
MH  - Glycosylation
MH  - In Situ Hybridization
MH  - Intercellular Signaling Peptides and Proteins
MH  - Mice
MH  - Molecular Sequence Data
MH  - Pregnancy
MH  - Prolactin
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Sequence Alignment
EDAT- 1999/10/28 00:00
MHDA- 1999/10/28 00:01
CRDT- 1999/10/28 00:00
PHST- 1999/10/28 00:00 [pubmed]
PHST- 1999/10/28 00:01 [medline]
PHST- 1999/10/28 00:00 [entrez]
AID - 10.1210/endo.140.11.7138 [doi]
PST - ppublish
SO  - Endocrinology. 1999 Nov;140(11):5095-101. doi: 10.1210/endo.140.11.7138.