PMID- 10527841
OWN - NLM
STAT- MEDLINE
DCOM- 19991112
LR  - 20070721
IS  - 0006-291X (Print)
IS  - 0006-291X (Linking)
VI  - 264
IP  - 1
DP  - 1999 Oct 14
TI  - BSMAP, a novel protein expressed specifically in the brain whose gene is
      localized on chromosome 19p12.
PG  - 55-62
AB  - Using the sequence of cosmids derived from chromosome 19p12, we have identified a
      gene encoding a novel protein, BSMAP (brain-specific membrane-anchored protein)
      and cloned cDNA encoding the full-length open reading frame. Northern blot
      analysis revealed that BSMAP mRNA is preferentially expressed at a high level in 
      the brain. BSMAP has a putative transmembrane domain and is predicted to be a
      type-I membrane glycoprotein. Genomic sequence analysis revealed that the gene
      encoding BSMAP consists of eight exons spanning approximately 8 kb and lies 6 kb 
      away from the gene encoding CLF-1 in a reverse orientation. Although no candidate
      genetic disorders were found to map either to this precise region of chromosome
      19 or to the syntenic region of the mouse genome, the highly specific expression 
      of BSMAP mRNA suggests a role for the protein in CNS function.
CI  - Copyright 1999 Academic Press.
FAU - Elson, G C
AU  - Elson GC
AD  - Centre d'Immunologie Pierre Fabre, St. Julien-en-Genevois, France.
      greg.elson@pierre-fabre.com
FAU - de Coignac, A B
AU  - de Coignac AB
FAU - Aubry, J P
AU  - Aubry JP
FAU - Delneste, Y
AU  - Delneste Y
FAU - Magistrelli, G
AU  - Magistrelli G
FAU - Holzwarth, J
AU  - Holzwarth J
FAU - Bonnefoy, J Y
AU  - Bonnefoy JY
FAU - Gauchat, J F
AU  - Gauchat JF
LA  - eng
SI  - GENBANK/AF186264
PT  - Journal Article
PL  - United States
TA  - Biochem Biophys Res Commun
JT  - Biochemical and biophysical research communications
JID - 0372516
RN  - 0 (DNA, Complementary)
RN  - 0 (Membrane Proteins)
RN  - 0 (Nerve Tissue Proteins)
RN  - 0 (Receptors, Cytokine)
RN  - 0 (TMEM59L protein, human)
RN  - 0 (cytokine-like factor-1)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Brain/*physiology
MH  - COS Cells
MH  - Chromosome Mapping
MH  - *Chromosomes, Human, Pair 19
MH  - Cloning, Molecular
MH  - DNA, Complementary/analysis
MH  - Humans
MH  - Membrane Proteins/biosynthesis/*genetics/metabolism
MH  - Molecular Sequence Data
MH  - Nerve Tissue Proteins/biosynthesis/*genetics/metabolism
MH  - Receptors, Cytokine/genetics
MH  - Sequence Homology, Amino Acid
MH  - Tissue Distribution
MH  - Transfection
EDAT- 1999/10/21 00:00
MHDA- 1999/10/21 00:01
CRDT- 1999/10/21 00:00
PHST- 1999/10/21 00:00 [pubmed]
PHST- 1999/10/21 00:01 [medline]
PHST- 1999/10/21 00:00 [entrez]
AID - 10.1006/bbrc.1999.1481 [doi]
AID - S0006-291X(99)91481-X [pii]
PST - ppublish
SO  - Biochem Biophys Res Commun. 1999 Oct 14;264(1):55-62. doi:
      10.1006/bbrc.1999.1481.