PMID- 10525310
OWN - NLM
STAT- MEDLINE
DCOM- 19991105
LR  - 20120605
IS  - 1043-4666 (Print)
IS  - 1043-4666 (Linking)
VI  - 11
IP  - 10
DP  - 1999 Oct
TI  - FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4.
PG  - 729-35
AB  - We have identified a novel fibroblast growth factor, FGF-19, the most distant
      member of the FGF family described to date. FGF-19 is a high affinity, heparin
      dependent ligand for FGFR4 and is the first member of the FGF family to show
      exclusive binding to FGFR4. Human FGF-19 maps to chromosome 11 q13.1, a region
      associated with an osteoporosis-pseudoglioma syndrome of skeletal and retinal
      defects. FGF-19 message is expressed in several tissues including fetal
      cartilage, skin, and retina, as well as adult gall bladder and is overexpressed
      in a colon adenocarcinoma cell line.
CI  - Copyright 1999 Academic Press.
FAU - Xie, M H
AU  - Xie MH
AD  - Department of Molecular Biology, Genentech Inc., 1 DNA Way, South San Francisco, 
      CA 94080, USA.
FAU - Holcomb, I
AU  - Holcomb I
FAU - Deuel, B
AU  - Deuel B
FAU - Dowd, P
AU  - Dowd P
FAU - Huang, A
AU  - Huang A
FAU - Vagts, A
AU  - Vagts A
FAU - Foster, J
AU  - Foster J
FAU - Liang, J
AU  - Liang J
FAU - Brush, J
AU  - Brush J
FAU - Gu, Q
AU  - Gu Q
FAU - Hillan, K
AU  - Hillan K
FAU - Goddard, A
AU  - Goddard A
FAU - Gurney, A L
AU  - Gurney AL
LA  - eng
SI  - GENBANK/AF110400
PT  - Journal Article
PL  - England
TA  - Cytokine
JT  - Cytokine
JID - 9005353
RN  - 0 (FGF19 protein, human)
RN  - 0 (Protein Sorting Signals)
RN  - 0 (RNA, Messenger)
RN  - 0 (Receptors, Fibroblast Growth Factor)
RN  - 0 (Recombinant Fusion Proteins)
RN  - 62031-54-3 (Fibroblast Growth Factors)
RN  - 9005-49-6 (Heparin)
RN  - EC 2.7.10.1 (FGFR4 protein, human)
RN  - EC 2.7.10.1 (Receptor, Fibroblast Growth Factor, Type 4)
SB  - IM
MH  - Adenocarcinoma
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Cell Division
MH  - Cell Line
MH  - Chromosomes, Human, Pair 11/genetics
MH  - Cloning, Molecular
MH  - Colorectal Neoplasms
MH  - Fibroblast Growth Factors/chemistry/*genetics/*metabolism
MH  - Gene Expression
MH  - Heparin/pharmacology
MH  - Humans
MH  - Molecular Sequence Data
MH  - Phylogeny
MH  - Physical Chromosome Mapping
MH  - Protein Binding/drug effects
MH  - Protein Sorting Signals
MH  - RNA, Messenger/analysis/genetics
MH  - Receptor, Fibroblast Growth Factor, Type 4
MH  - Receptors, Fibroblast Growth Factor/genetics/*metabolism
MH  - Recombinant Fusion Proteins/chemistry/metabolism
MH  - Retina/embryology/metabolism
MH  - Sequence Alignment
MH  - Syndrome
MH  - Tumor Cells, Cultured
EDAT- 1999/10/20 00:00
MHDA- 1999/10/20 00:01
CRDT- 1999/10/20 00:00
PHST- 1999/10/20 00:00 [pubmed]
PHST- 1999/10/20 00:01 [medline]
PHST- 1999/10/20 00:00 [entrez]
AID - 10.1006/cyto.1999.0485 [doi]
AID - S1043-4666(99)90485-4 [pii]
PST - ppublish
SO  - Cytokine. 1999 Oct;11(10):729-35. doi: 10.1006/cyto.1999.0485.