PMID- 10524214
OWN - NLM
STAT- MEDLINE
DCOM- 19991104
LR  - 20190610
IS  - 0006-3002 (Print)
IS  - 0006-3002 (Linking)
VI  - 1446
IP  - 3
DP  - 1999 Sep 3
TI  - Identification and expression of a cDNA for human hydroxypyruvate/glyoxylate
      reductase.
PG  - 383-8
AB  - The isolation and expression of a human liver cDNA encoding a 40-kDa protein with
      glyoxylate and hydroxypyruvate reductase activities is described. The cDNA (GLXR)
      is 1235 bp and consists of a predicted open reading frame of 987 bp with a 225-bp
      3'-untranslated region. The 328-amino acid protein has partial sequence
      similarity to hydroxypyruvate and glyoxylate reductases from a variety of plant
      and microbial species.
FAU - Rumsby, G
AU  - Rumsby G
AD  - Department of Molecular Pathology, University College London, Windeyer Institute 
      of Medical Sciences, UK. g.rumsby@academic.uclh.nthames.nhs.uk
FAU - Cregeen, D P
AU  - Cregeen DP
LA  - eng
SI  - GENBANK/AF134895
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Biochim Biophys Acta
JT  - Biochimica et biophysica acta
JID - 0217513
RN  - 0 (DNA, Complementary)
RN  - 0 (Recombinant Fusion Proteins)
RN  - EC 1.1.- (Alcohol Oxidoreductases)
RN  - EC 1.1.- (Carbohydrate Dehydrogenases)
RN  - EC 1.1.1.26 (glyoxylate reductase)
RN  - EC 1.1.1.29 (Glycerate dehydrogenase)
RN  - EC 1.1.1.81 (Hydroxypyruvate Reductase)
RN  - EC 1.1.3.15 (glycollate oxidase)
RN  - EC 2.6.1.- (Transaminases)
RN  - EC 2.6.1.44 (Alanine-glyoxylate transaminase)
SB  - IM
MH  - Alcohol Oxidoreductases/*genetics/metabolism
MH  - Amino Acid Sequence
MH  - Base Sequence
MH  - Carbohydrate Dehydrogenases/genetics
MH  - Cell Line
MH  - Cytosol/metabolism
MH  - DNA, Complementary/*chemistry
MH  - Gene Expression
MH  - Humans
MH  - Hydroxypyruvate Reductase
MH  - Hyperoxaluria, Primary/enzymology/genetics
MH  - Liver/*enzymology
MH  - Molecular Sequence Data
MH  - Peroxisomes/metabolism
MH  - Polymerase Chain Reaction
MH  - Recombinant Fusion Proteins/*genetics
MH  - Sequence Alignment
MH  - Transaminases/metabolism
MH  - Transfection
EDAT- 1999/10/19 00:00
MHDA- 1999/10/19 00:01
CRDT- 1999/10/19 00:00
PHST- 1999/10/19 00:00 [pubmed]
PHST- 1999/10/19 00:01 [medline]
PHST- 1999/10/19 00:00 [entrez]
AID - S0167-4781(99)00105-0 [pii]
AID - 10.1016/s0167-4781(99)00105-0 [doi]
PST - ppublish
SO  - Biochim Biophys Acta. 1999 Sep 3;1446(3):383-8. doi:
      10.1016/s0167-4781(99)00105-0.