PMID- 10518929
OWN - NLM
STAT- MEDLINE
DCOM- 19991028
LR  - 20190621
IS  - 0014-5793 (Print)
IS  - 0014-5793 (Linking)
VI  - 458
IP  - 1
DP  - 1999 Sep 10
TI  - Molecular cloning of mXCR1, the murine SCM-1/lymphotactin receptor.
PG  - 37-40
AB  - Single C motif-1 (SCM-1)/lymphotactin is a C-type member of the chemokine
      superfamily. Previously, we identified its specific receptor XCR1. Here we
      isolated the murine homologue of XCR1 (mXCR1). To demonstrate its biological
      activity, we produced recombinant mouse SCM-1 by the baculovirus expression
      system. B300-19 murine pre-B cells expressing mXCR1 responded to mSCM-1 in
      chemotactic and calcium-mobilization assays. mXCR1 mRNA was weakly expressed in
      spleen and lung of normal C57BL/6 mice. In spleen, CD8+ cells and NK1.1+ cells
      were found to express mXCR1. Identification of mXCR1 will now allow us to study
      the role of this unique cytokine system in the mouse models of inflammation and
      immunity.
FAU - Yoshida, T
AU  - Yoshida T
AD  - Shionogi Institute for Medical Science, Osaka, Japan.
FAU - Izawa, D
AU  - Izawa D
FAU - Nakayama, T
AU  - Nakayama T
FAU - Nakahara, K
AU  - Nakahara K
FAU - Kakizaki, M
AU  - Kakizaki M
FAU - Imai, T
AU  - Imai T
FAU - Suzuki, R
AU  - Suzuki R
FAU - Miyasaka, M
AU  - Miyasaka M
FAU - Yoshie, O
AU  - Yoshie O
LA  - eng
SI  - GENBANK/AB028459
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - FEBS Lett
JT  - FEBS letters
JID - 0155157
RN  - 0 (Membrane Proteins)
RN  - 0 (Receptors, Cell Surface)
RN  - 0 (Receptors, Chemokine)
RN  - 0 (Receptors, G-Protein-Coupled)
RN  - 0 (Recombinant Proteins)
RN  - 0 (XC chemokine receptor 1, mouse)
RN  - 0 (XCR1 protein, human)
RN  - SY7Q814VUP (Calcium)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Calcium/metabolism
MH  - Cell Fractionation
MH  - Cell Line
MH  - Chemotaxis
MH  - Chromatography, High Pressure Liquid
MH  - Cloning, Molecular
MH  - Dose-Response Relationship, Drug
MH  - Female
MH  - Gene Expression
MH  - *Membrane Proteins
MH  - Mice
MH  - Mice, Inbred C57BL
MH  - Molecular Sequence Data
MH  - Receptors, Cell Surface/*genetics/*physiology
MH  - Receptors, Chemokine/*genetics/*physiology
MH  - *Receptors, G-Protein-Coupled
MH  - Recombinant Proteins/biosynthesis
MH  - Reverse Transcriptase Polymerase Chain Reaction
MH  - Sequence Homology, Amino Acid
MH  - Spleen/metabolism
MH  - Time Factors
MH  - Tissue Distribution
EDAT- 1999/10/16 00:00
MHDA- 1999/10/16 00:01
CRDT- 1999/10/16 00:00
PHST- 1999/10/16 00:00 [pubmed]
PHST- 1999/10/16 00:01 [medline]
PHST- 1999/10/16 00:00 [entrez]
AID - S0014-5793(99)01114-X [pii]
AID - 10.1016/s0014-5793(99)01114-x [doi]
PST - ppublish
SO  - FEBS Lett. 1999 Sep 10;458(1):37-40. doi: 10.1016/s0014-5793(99)01114-x.