PMID- 10518023
OWN - NLM
STAT- MEDLINE
DCOM- 19991124
LR  - 20190621
IS  - 0014-5793 (Print)
IS  - 0014-5793 (Linking)
VI  - 459
IP  - 2
DP  - 1999 Oct 8
TI  - Identification of the cDNA encoding human 6-phosphogluconolactonase, the enzyme
      catalyzing the second step of the pentose phosphate pathway(1).
PG  - 223-6
AB  - We report the sequence of a human cDNA encoding a protein homologous to devB (a
      bacterial gene often found in proximity to the gene encoding glucose-6-phosphate 
      dehydrogenase in bacterial genomes) and to the C-terminal part of human
      hexose-6-phosphate dehydrogenase. The protein was expressed in Escherichia coli, 
      purified and shown to be 6-phosphogluconolactonase, the enzyme catalyzing the
      second step of the pentose phosphate pathway. Sequence analysis indicates that
      bacterial devB proteins, the C-terminal part of hexose-6-phosphate dehydrogenase 
      and yeast Sol1-4 proteins are most likely also 6-phosphogluconolactonases and
      that these proteins are related to glucosamine-6-phosphate isomerases.
FAU - Collard, F
AU  - Collard F
AD  - Laboratory of Physiological Chemistry, Universite catholique de Louvain and
      Christian de Duve Institute of Cellular Pathology, 7539 Avenue Hippocrate,
      B-1200, Brussels, Belgium.
FAU - Collet, J F
AU  - Collet JF
FAU - Gerin, I
AU  - Gerin I
FAU - Veiga-da-Cunha, M
AU  - Veiga-da-Cunha M
FAU - Van Schaftingen, E
AU  - Van Schaftingen E
LA  - eng
SI  - GENBANK/AJ243972
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - FEBS Lett
JT  - FEBS letters
JID - 0155157
RN  - 0 (DNA, Complementary)
RN  - EC 3.1.1.- (Carboxylic Ester Hydrolases)
RN  - EC 3.1.1.31 (6-phosphogluconolactonase)
SB  - IM
MH  - Amino Acid Sequence
MH  - Base Sequence
MH  - Carboxylic Ester Hydrolases/*genetics/metabolism
MH  - Catalysis
MH  - Chromosome Mapping
MH  - Chromosomes, Human, Pair 19
MH  - DNA, Complementary/isolation & purification
MH  - Humans
MH  - Molecular Sequence Data
MH  - Pentose Phosphate Pathway/*genetics
MH  - Sequence Homology, Amino Acid
EDAT- 1999/10/13 00:00
MHDA- 1999/10/13 00:01
CRDT- 1999/10/13 00:00
PHST- 1999/10/13 00:00 [pubmed]
PHST- 1999/10/13 00:01 [medline]
PHST- 1999/10/13 00:00 [entrez]
AID - S0014579399012478 [pii]
AID - 10.1016/s0014-5793(99)01247-8 [doi]
PST - ppublish
SO  - FEBS Lett. 1999 Oct 8;459(2):223-6. doi: 10.1016/s0014-5793(99)01247-8.