PMID- 10516439
OWN - NLM
STAT- MEDLINE
DCOM- 19991027
LR  - 20171101
IS  - 0301-0171 (Print)
IS  - 0301-0171 (Linking)
VI  - 86
IP  - 1
DP  - 1999
TI  - Gene structure and chromosome mapping of the human small-conductance
      calcium-activated potassium channel SK1 gene (KCNN1).
PG  - 70-3
AB  - Small-conductance, calcium-activated potassium channels contribute to the
      afterhyperpolarization in central neurons and other cell types. Because these
      channels regulate neuronal excitability, defects in their genes could cause
      excitability disorders. The human cDNA encoding one such channel, SK1 (KCNN1),
      was recently cloned. Here we describe the gene structure of KCNN1 and its
      localization by radiation hybrid mapping to chromosome 19p13.1.
FAU - Litt, M
AU  - Litt M
AD  - Department of Molecular and Medical Genetics, Oregon Health Sciences University, 
      Portland OR (USA).
FAU - LaMorticella, D
AU  - LaMorticella D
FAU - Bond, C T
AU  - Bond CT
FAU - Adelman, J P
AU  - Adelman JP
LA  - eng
SI  - GENBANK/U69883
GR  - 5RO1EY11710/EY/NEI NIH HHS/United States
GR  - GM58259/GM/NIGMS NIH HHS/United States
GR  - NS36800/NS/NINDS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Switzerland
TA  - Cytogenet Cell Genet
JT  - Cytogenetics and cell genetics
JID - 0367735
RN  - 0 (KCNN1 protein, human)
RN  - 0 (Potassium Channels)
RN  - 0 (Potassium Channels, Calcium-Activated)
RN  - 0 (Small-Conductance Calcium-Activated Potassium Channels)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Chromosomes, Human, Pair 19/*genetics
MH  - Cloning, Molecular
MH  - Exons/genetics
MH  - Genomic Library
MH  - Humans
MH  - Hybrid Cells
MH  - Introns/genetics
MH  - Mice
MH  - Molecular Sequence Data
MH  - *Physical Chromosome Mapping
MH  - Polymerase Chain Reaction
MH  - Potassium Channels/*genetics
MH  - *Potassium Channels, Calcium-Activated
MH  - Sequence Homology, Nucleic Acid
MH  - Small-Conductance Calcium-Activated Potassium Channels
EDAT- 1999/10/12 00:00
MHDA- 1999/10/12 00:01
CRDT- 1999/10/12 00:00
PHST- 1999/10/12 00:00 [pubmed]
PHST- 1999/10/12 00:01 [medline]
PHST- 1999/10/12 00:00 [entrez]
AID - 15415 [pii]
AID - 10.1159/000015415 [doi]
PST - ppublish
SO  - Cytogenet Cell Genet. 1999;86(1):70-3. doi: 10.1159/000015415.