PMID- 10500249
OWN - NLM
STAT- MEDLINE
DCOM- 19991105
LR  - 20190610
IS  - 0006-3002 (Print)
IS  - 0006-3002 (Linking)
VI  - 1447
IP  - 1
DP  - 1999 Oct 6
TI  - Complete genomic structure of the CLCN6 and CLCN7 putative chloride channel
      genes(1).
PG  - 100-6
AB  - The CLC family of voltage-gated chloride channels comprises nine members in
      mammals. CLCN6 and CLCN7 belong to a novel, poorly characterized subbranch of
      this family. We investigated the genomic organization of the human CLCN6 gene, as
      well as the murine CLCN6 and CLCN7 genes. The human and murine CLCN6 genes both
      consist of 23 exons and share a nearly identical genomic structure. The coding
      region of mouse CLCN7 is composed of 25 exons. Comparison of the genomic
      organization of CLCN6 and CLCN7 genes shows that just eight introns are located
      at corresponding cDNA positions. Moreover, no significant gene structure homology
      to other members of the CLC family could be detected indicating a great
      structural diversity of mammalian CLC genes.
FAU - Kornak, U
AU  - Kornak U
AD  - Zentrum fur Molekulare Neurobiologie Hamburg (ZMNH), Universitat Hamburg,
      Martinistrasse 85, 20246, Hamburg, Germany.
FAU - Bosl, M R
AU  - Bosl MR
FAU - Kubisch, C
AU  - Kubisch C
LA  - eng
SI  - GENBANK/AF009247
SI  - GENBANK/AF009248
SI  - GENBANK/AF009249
SI  - GENBANK/AF009250
SI  - GENBANK/AF009251
SI  - GENBANK/AF009252
SI  - GENBANK/AF009253
SI  - GENBANK/AF009254
SI  - GENBANK/AF009255
SI  - GENBANK/AF009256
SI  - GENBANK/AF009257
SI  - GENBANK/AF030101
SI  - GENBANK/AF030102
SI  - GENBANK/AF030103
SI  - GENBANK/AF030104
SI  - GENBANK/AF030105
SI  - GENBANK/AF030106
SI  - GENBANK/AF063098
SI  - GENBANK/AF063099
SI  - GENBANK/AF063100
SI  - GENBANK/AF063101
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Biochim Biophys Acta
JT  - Biochimica et biophysica acta
JID - 0217513
RN  - 0 (CLCN6 protein, human)
RN  - 0 (CLCN7 protein, human)
RN  - 0 (Chloride Channels)
RN  - 0 (Clcn6 protein, mouse)
RN  - 0 (Clcn7 protein, mouse)
RN  - 0 (DNA, Complementary)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Chloride Channels/chemistry/*genetics
MH  - DNA, Complementary/chemistry
MH  - Exons
MH  - Humans
MH  - Introns
MH  - Mice
MH  - Molecular Sequence Data
MH  - Polymerase Chain Reaction
MH  - Promoter Regions, Genetic
MH  - Sequence Alignment
EDAT- 1999/09/29 00:00
MHDA- 1999/09/29 00:01
CRDT- 1999/09/29 00:00
PHST- 1999/09/29 00:00 [pubmed]
PHST- 1999/09/29 00:01 [medline]
PHST- 1999/09/29 00:00 [entrez]
AID - S0167478199001281 [pii]
AID - 10.1016/s0167-4781(99)00128-1 [doi]
PST - ppublish
SO  - Biochim Biophys Acta. 1999 Oct 6;1447(1):100-6. doi:
      10.1016/s0167-4781(99)00128-1.