PMID- 10495285 OWN - NLM STAT- MEDLINE DCOM- 20000316 LR - 20190910 IS - 0925-4773 (Print) IS - 0925-4773 (Linking) VI - 87 IP - 1-2 DP - 1999 Sep TI - Mml, a mouse Mix-like gene expressed in the primitive streak. PG - 189-92 AB - A mouse Mix-like gene, Mml, related to the Xenopus Mix/Bix homeobox gene family and the chick CMIX gene has been identified. At E5.5, Mml is expressed symmetrically in the visceral endoderm but by E6.0 this expression is noticeably asymmetric. At E6.5, expression is restricted to the nascent primitive streak. Mml expression persists in the primitive streak through E7.5-E9.5, marking those cells fated to form extra-embryonic and lateral mesoderm. FAU - Pearce, J J AU - Pearce JJ AD - Wellcome/CRC Institute and Department of Genetics, Tennis Court Road, Cambridge, UK. jpp27@mole.bio.cam.ac.uk FAU - Evans, M J AU - Evans MJ LA - eng SI - GENBANK/AF135063 GR - Wellcome Trust/United Kingdom PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Ireland TA - Mech Dev JT - Mechanisms of development JID - 9101218 RN - 0 (Avian Proteins) RN - 0 (CMIX protein, chicken) RN - 0 (Homeodomain Proteins) RN - 0 (Mix1 protein, Xenopus) RN - 0 (Mixl1 protein, mouse) RN - 0 (Xenopus Proteins) SB - IM MH - Amino Acid Sequence MH - Animals MH - *Avian Proteins MH - Endoderm/metabolism MH - Gastrula/*metabolism MH - *Gene Expression MH - Homeodomain Proteins/genetics/*metabolism MH - Mesoderm/metabolism MH - Mice MH - Molecular Sequence Data MH - Phylogeny MH - Sequence Homology, Amino Acid MH - Time Factors MH - *Xenopus Proteins EDAT- 1999/09/24 09:00 MHDA- 2000/03/18 09:00 CRDT- 1999/09/24 09:00 PHST- 1999/09/24 09:00 [pubmed] PHST- 2000/03/18 09:00 [medline] PHST- 1999/09/24 09:00 [entrez] AID - S0925-4773(99)00135-5 [pii] AID - 10.1016/s0925-4773(99)00135-5 [doi] PST - ppublish SO - Mech Dev. 1999 Sep;87(1-2):189-92. doi: 10.1016/s0925-4773(99)00135-5.