PMID- 10461187
OWN - NLM
STAT- MEDLINE
DCOM- 19991020
LR  - 20191024
IS  - 0962-8924 (Print)
IS  - 0962-8924 (Linking)
VI  - 9
IP  - 9
DP  - 1999 Sep
TI  - The coronin family of actin-associated proteins.
PG  - 345-50
AB  - Coronin was first isolated from Dictyostelium, but similar proteins have been
      identified in many species and individual cell types. The coronin-like protein in
      yeast promotes actin polymerization and also interacts with microtubules.
      Dictyostelium mutants lacking coronin are impaired in cytokinesis and all
      actin-mediated processes. Analysis of coronin-GFP (green-fluorescent protein)
      fusions and knockout mutants shows that coronin participates in the remodelling
      of the cortical actin cytoskeleton that is responsible for phagocytosis and
      macropinocytosis. Likewise, in mammalian neutrophils, a coronin-like protein is
      also associated with the phagocytic apparatus. The diversity of function in this 
      family of actin-associated proteins is just beginning to be explored.
FAU - de Hostos, E L
AU  - de Hostos EL
AD  - Tropical Disease Research Unit, University of California, San Francisco, VAMC
      113B, 4150 Clement St, San Francisco, CA 94121, USA. hostos@socrates.ucsf.edu
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Review
PL  - England
TA  - Trends Cell Biol
JT  - Trends in cell biology
JID - 9200566
RN  - 0 (Actins)
RN  - 0 (Biopolymers)
RN  - 0 (Fungal Proteins)
RN  - 0 (Helminth Proteins)
RN  - 0 (Microfilament Proteins)
RN  - 145420-64-0 (coronin proteins)
SB  - IM
MH  - Actins/metabolism
MH  - Amino Acid Sequence
MH  - Animals
MH  - Biopolymers
MH  - Dictyostelium/genetics/metabolism
MH  - Endocytosis
MH  - Forecasting
MH  - Fungal Proteins/genetics/isolation & purification/physiology
MH  - Helminth Proteins/chemistry/genetics
MH  - Humans
MH  - Mammals/metabolism
MH  - *Microfilament Proteins/genetics/isolation &
      purification/physiology/ultrastructure
MH  - Microtubules/metabolism
MH  - Molecular Sequence Data
MH  - Phosphorylation
MH  - Protein Processing, Post-Translational
MH  - Sequence Alignment
MH  - Sequence Homology, Amino Acid
RF  - 29
EDAT- 1999/08/26 00:00
MHDA- 1999/08/26 00:01
CRDT- 1999/08/26 00:00
PHST- 1999/08/26 00:00 [pubmed]
PHST- 1999/08/26 00:01 [medline]
PHST- 1999/08/26 00:00 [entrez]
AID - S0962-8924(99)01620-7 [pii]
AID - 10.1016/s0962-8924(99)01620-7 [doi]
PST - ppublish
SO  - Trends Cell Biol. 1999 Sep;9(9):345-50. doi: 10.1016/s0962-8924(99)01620-7.