PMID- 10461185
OWN - NLM
STAT- MEDLINE
DCOM- 19991020
LR  - 20191024
IS  - 0962-8924 (Print)
IS  - 0962-8924 (Linking)
VI  - 9
IP  - 9
DP  - 1999 Sep
TI  - Clathrin: anatomy of a coat protein.
PG  - 335-8
AB  - Clathrin is a vesicle coat protein involved in the assembly of membrane and cargo
      into transport vesicles at the plasma membrane and on certain intracellular
      organelles. Recently, crystal structures of two separate parts of the clathrin
      heavy chain, a fragment of the proximal leg and the N-terminal domain, have been 
      analysed, providing the first high-resolution data for a vesicle coat protein.
      Viewing these structures in the context of a hexagonal barrel coat, recently
      determined to 21 A by cryo-electron microscopy, provides new insights into the
      assembly of clathrin coats.
FAU - Smith, C J
AU  - Smith CJ
AD  - MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK CB2 2QH.
FAU - Pearse, B M
AU  - Pearse BM
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Trends Cell Biol
JT  - Trends in cell biology
JID - 9200566
RN  - 0 (Clathrin)
RN  - 0 (Macromolecular Substances)
SB  - IM
MH  - Animals
MH  - Clathrin/*chemistry/ultrastructure
MH  - Coated Pits, Cell-Membrane/chemistry/ultrastructure
MH  - Cryoelectron Microscopy
MH  - Crystallography, X-Ray
MH  - Macromolecular Substances
MH  - *Protein Conformation
MH  - Structure-Activity Relationship
RF  - 32
EDAT- 1999/08/26 00:00
MHDA- 1999/08/26 00:01
CRDT- 1999/08/26 00:00
PHST- 1999/08/26 00:00 [pubmed]
PHST- 1999/08/26 00:01 [medline]
PHST- 1999/08/26 00:00 [entrez]
AID - S0962-8924(99)01631-1 [pii]
AID - 10.1016/s0962-8924(99)01631-1 [doi]
PST - ppublish
SO  - Trends Cell Biol. 1999 Sep;9(9):335-8. doi: 10.1016/s0962-8924(99)01631-1.