PMID- 10454592
OWN - NLM
STAT- MEDLINE
DCOM- 19990907
LR  - 20190501
IS  - 1362-4962 (Electronic)
IS  - 0305-1048 (Linking)
VI  - 27
IP  - 15
DP  - 1999 Aug 1
TI  - A tale of three fingers: the family of mammalian Sp/XKLF transcription factors.
PG  - 2991-3000
AB  - One of the most common regulatory elements is the GC box and the related GT/CACC 
      box, which are widely distributed in promoters, enhancers and locus control
      regions of housekeeping as well as tissue-specific genes. For long it was
      generally thought that Sp1 is the major factor acting through these motifs.
      Recent discoveries have shown that Sp1 is only one of many transcription factors 
      binding and acting through these elements. Sp1 simply represents the first
      identified and cloned protein of a family of transcription factors characterised 
      by a highly conserved DNA-binding domain consisting of three zinc fingers.
      Currently this new family of transcription factors has at least 16 different
      mammalian members. Here, we will summarise and discuss recent advances that have 
      been directed towards understanding the biological role of these proteins.
FAU - Philipsen, S
AU  - Philipsen S
AD  - Department of Cell Biology, Erasmus University Rotterdam, PO Box 1738, 3000 DR
      Rotterdam, The Netherlands and.
FAU - Suske, G
AU  - Suske G
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Nucleic Acids Res
JT  - Nucleic acids research
JID - 0411011
RN  - 0 (Sp1 Transcription Factor)
RN  - 0 (Transcription Factors)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Gene Expression Regulation
MH  - Humans
MH  - Molecular Sequence Data
MH  - Sequence Homology, Amino Acid
MH  - Sp1 Transcription Factor/chemistry/classification/*metabolism
MH  - Terminology as Topic
MH  - Transcription Factors/chemistry/classification/*metabolism
MH  - *Zinc Fingers
RF  - 113
PMC - PMC148522
EDAT- 1999/08/24 00:00
MHDA- 1999/08/24 00:01
CRDT- 1999/08/24 00:00
PHST- 1999/08/24 00:00 [pubmed]
PHST- 1999/08/24 00:01 [medline]
PHST- 1999/08/24 00:00 [entrez]
AID - gkc472 [pii]
AID - 10.1093/nar/27.15.2991 [doi]
PST - ppublish
SO  - Nucleic Acids Res. 1999 Aug 1;27(15):2991-3000. doi: 10.1093/nar/27.15.2991.