PMID- 10452948
OWN - NLM
STAT- MEDLINE
DCOM- 19990923
LR  - 20190707
IS  - 0378-1119 (Print)
IS  - 0378-1119 (Linking)
VI  - 236
IP  - 2
DP  - 1999 Aug 20
TI  - Small subfamily of olfactory receptor genes: structural features, expression
      pattern and genomic organization.
PG  - 281-91
AB  - Olfactory receptors of the OR37 subfamily are characterized by distinct sequence 
      features and are expressed in neurons segregated in a restricted area of the
      olfactory epithelium. In the present study, we have characterized the complement 
      of OR37-like genes in the mouse. Five OR37-like genes were identified. They
      reside within only 60kb of DNA on chromosome 4. About 70kb distant from this
      cluster, two additional olfactory receptor genes are located, which are members
      of distinct receptor subfamilies. Phylogenetic analysis demonstrated that the two
      physically linked receptors are closely related to the OR37 subfamily. Studies of
      gene expression showed that both genes are also expressed in clustered neuron
      populations located in the typical OR37 region of the epithelium. These data
      suggest the involvement of locus-dependent mechanisms for the spatial control of 
      OR gene expression.
FAU - Strotmann, J
AU  - Strotmann J
AD  - Institute of Physiology, University Stuttgart-Hohenheim, Garbenstrasse 30,
      D-70593, Stuttgart, Germany.
FAU - Hoppe, R
AU  - Hoppe R
FAU - Conzelmann, S
AU  - Conzelmann S
FAU - Feinstein, P
AU  - Feinstein P
FAU - Mombaerts, P
AU  - Mombaerts P
FAU - Breer, H
AU  - Breer H
LA  - eng
SI  - GENBANK/AJ133424
SI  - GENBANK/AJ133425
SI  - GENBANK/AJ133426
SI  - GENBANK/AJ133427
SI  - GENBANK/AJ133428
SI  - GENBANK/AJ133429
SI  - GENBANK/AJ133430
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Gene
JT  - Gene
JID - 7706761
RN  - 0 (Amino Acids)
RN  - 0 (Receptors, Odorant)
SB  - IM
MH  - Amino Acids/analysis
MH  - Animals
MH  - Base Sequence
MH  - Chromosome Mapping
MH  - Gene Library
MH  - In Situ Hybridization
MH  - In Situ Hybridization, Fluorescence
MH  - Mice
MH  - Models, Genetic
MH  - Molecular Sequence Data
MH  - Multigene Family
MH  - Nasal Cavity/anatomy & histology
MH  - Phylogeny
MH  - Receptors, Odorant/*genetics
MH  - Reverse Transcriptase Polymerase Chain Reaction
MH  - Tissue Distribution
EDAT- 1999/08/24 00:00
MHDA- 1999/08/24 00:01
CRDT- 1999/08/24 00:00
PHST- 1999/08/24 00:00 [pubmed]
PHST- 1999/08/24 00:01 [medline]
PHST- 1999/08/24 00:00 [entrez]
AID - S0378111999002759 [pii]
AID - 10.1016/s0378-1119(99)00275-9 [doi]
PST - ppublish
SO  - Gene. 1999 Aug 20;236(2):281-91. doi: 10.1016/s0378-1119(99)00275-9.