PMID- 10449330
OWN - NLM
STAT- MEDLINE
DCOM- 19991110
LR  - 20190915
IS  - 0955-0674 (Print)
IS  - 0955-0674 (Linking)
VI  - 11
IP  - 4
DP  - 1999 Aug
TI  - Membrane tethering in intracellular transport.
PG  - 453-9
AB  - Studies of various membrane trafficking steps over the past year indicate that
      membranes are tethered together prior to the interaction of v-SNAREs and t-SNAREs
      across the membrane junction. The tethering proteins identified to date are quite
      large, being either fibrous proteins or multimeric protein complexes. The
      tethering factors employed at different steps are evolutionarily unrelated, yet
      their function seems to be closely tied to the more highly conserved Rab GTPases.
      Tethering factors may collaborate with Rabs and SNAREs to generate targeting
      specificity in the secretory pathway.
FAU - Waters, M G
AU  - Waters MG
AD  - Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. 
      gwaters@molbio.princeton.edu
FAU - Pfeffer, S R
AU  - Pfeffer SR
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Curr Opin Cell Biol
JT  - Current opinion in cell biology
JID - 8913428
RN  - 0 (Membrane Proteins)
RN  - 0 (SNARE Proteins)
RN  - 0 (Vesicular Transport Proteins)
SB  - IM
MH  - Animals
MH  - Biological Transport
MH  - Endosomes
MH  - Golgi Apparatus/metabolism
MH  - Intracellular Membranes/*metabolism
MH  - Membrane Proteins/*metabolism
MH  - SNARE Proteins
MH  - Saccharomyces cerevisiae
MH  - Vacuoles
MH  - *Vesicular Transport Proteins
RF  - 71
EDAT- 1999/08/17 00:00
MHDA- 1999/08/17 00:01
CRDT- 1999/08/17 00:00
PHST- 1999/08/17 00:00 [pubmed]
PHST- 1999/08/17 00:01 [medline]
PHST- 1999/08/17 00:00 [entrez]
AID - cbb404 [pii]
AID - 10.1016/s0955-0674(99)80065-9 [doi]
PST - ppublish
SO  - Curr Opin Cell Biol. 1999 Aug;11(4):453-9. doi: 10.1016/s0955-0674(99)80065-9.