PMID- 10446990
OWN - NLM
STAT- MEDLINE
DCOM- 19990907
LR  - 20190524
IS  - 0008-5472 (Print)
IS  - 0008-5472 (Linking)
VI  - 59
IP  - 15
DP  - 1999 Aug 1
TI  - Bdp, a new member of a family of DNA-binding proteins, associates with the
      retinoblastoma gene product.
PG  - 3741-7
AB  - We have cloned a gene, BDP, encoding a protein with homology to the
      retinoblastoma-binding proteins Rbp1 and Rbp2. It also has homology to
      DNA-binding proteins such as Bright, a B-cell-specific trans-activator, and the
      Drosophila melanogaster dead ringer gene product. Like MyoD, Bdp binds to the
      COOH-terminal region of pRb through its conserved region and to
      hypophosphorylated pRb. It also binds to the MAR of the immunoglobulin
      heavy-chain locus. Thus Bdp may contribute to the transcriptional regulation of
      genes involved in differentiation and tissue-specific expression.
FAU - Numata, S
AU  - Numata S
AD  - Kimmel Cancer Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 
      19107, USA.
FAU - Claudio, P P
AU  - Claudio PP
FAU - Dean, C
AU  - Dean C
FAU - Giordano, A
AU  - Giordano A
FAU - Croce, C M
AU  - Croce CM
LA  - eng
GR  - CA21124/CA/NCI NIH HHS/United States
GR  - CA39880/CA/NCI NIH HHS/United States
GR  - CA51083/CA/NCI NIH HHS/United States
GR  - etc.
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Cancer Res
JT  - Cancer research
JID - 2984705R
RN  - 0 (ARID3A protein, human)
RN  - 0 (ARID3B protein, human)
RN  - 0 (DNA, Complementary)
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (Drosophila Proteins)
RN  - 0 (Homeodomain Proteins)
RN  - 0 (Insect Proteins)
RN  - 0 (Neoplasm Proteins)
RN  - 0 (Nuclear Proteins)
RN  - 0 (Recombinant Fusion Proteins)
RN  - 0 (Retinoblastoma Protein)
RN  - 0 (Retn protein, Drosophila)
RN  - 0 (Trans-Activators)
RN  - 0 (Transcription Factors)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Binding Sites
MH  - Brain Neoplasms/genetics/pathology
MH  - Chromosome Mapping
MH  - Chromosomes, Human, Pair 15/*genetics
MH  - DNA, Complementary/genetics
MH  - DNA-Binding Proteins/chemistry/*genetics/metabolism
MH  - *Drosophila Proteins
MH  - Drosophila melanogaster/genetics
MH  - Expressed Sequence Tags
MH  - Gene Library
MH  - Glioblastoma/genetics/pathology
MH  - HeLa Cells
MH  - Homeodomain Proteins/genetics
MH  - Humans
MH  - Insect Proteins/genetics
MH  - Molecular Sequence Data
MH  - Molecular Weight
MH  - *Multigene Family
MH  - Neoplasm Proteins/*genetics/metabolism
MH  - Nuclear Proteins/genetics/metabolism
MH  - *Oncogenes
MH  - Phosphorylation
MH  - Protein Binding
MH  - Protein Processing, Post-Translational
MH  - Recombinant Fusion Proteins/metabolism
MH  - Retinoblastoma Protein/*metabolism
MH  - Sequence Alignment
MH  - Sequence Homology, Amino Acid
MH  - Trans-Activators/chemistry/genetics
MH  - Transcription Factors
MH  - Transfection
MH  - Tumor Cells, Cultured
EDAT- 1999/08/14 00:00
MHDA- 1999/08/14 00:01
CRDT- 1999/08/14 00:00
PHST- 1999/08/14 00:00 [pubmed]
PHST- 1999/08/14 00:01 [medline]
PHST- 1999/08/14 00:00 [entrez]
PST - ppublish
SO  - Cancer Res. 1999 Aug 1;59(15):3741-7.