PMID- 10445032
OWN - NLM
STAT- MEDLINE
DCOM- 19990830
LR  - 20190915
IS  - 1097-2765 (Print)
IS  - 1097-2765 (Linking)
VI  - 4
IP  - 1
DP  - 1999 Jul
TI  - Lipotransin: a novel docking protein for hormone-sensitive lipase.
PG  - 109-15
AB  - Lipotransin is a novel hormone-sensitive lipase (HSL)-interacting protein that
      appears to translocate HSL to the lipid droplet. The interaction of the two
      proteins depends upon the phosphorylation of HSL by protein kinase A. Once
      formed, the complex is dissociated by ATP hydrolysis, due to the ATPase activity 
      of lipotransin. In 3T3L1 adipocytes, insulin produces a stable complex between
      the proteins, due to a modification of lipotransin. Thus, lipotransin is a novel 
      docking protein that may direct the hormonally regulated redistribution of
      hormone-sensitive lipase.
FAU - Syu, L J
AU  - Syu LJ
AD  - Department of Physiology, University of Michigan School of Medicine, Ann Arbor
      49109, USA.
FAU - Saltiel, A R
AU  - Saltiel AR
LA  - eng
SI  - GENBANK/AF153197
PT  - Journal Article
PL  - United States
TA  - Mol Cell
JT  - Molecular cell
JID - 9802571
RN  - 0 (Carrier Proteins)
RN  - 0 (Insulin)
RN  - 0 (RNA, Messenger)
RN  - 8L70Q75FXE (Adenosine Triphosphate)
RN  - EC 2.7.11.11 (Cyclic AMP-Dependent Protein Kinases)
RN  - EC 3.1.1.13 (Sterol Esterase)
SB  - IM
MH  - 3T3 Cells
MH  - Adenosine Triphosphate/metabolism
MH  - Animals
MH  - Biological Transport
MH  - Carrier Proteins/genetics/*metabolism
MH  - Cyclic AMP-Dependent Protein Kinases/metabolism
MH  - Gene Expression Regulation
MH  - Insulin/pharmacology
MH  - Lipolysis
MH  - Mice
MH  - Molecular Sequence Data
MH  - Phosphorylation
MH  - Protein Binding
MH  - RNA, Messenger/genetics
MH  - Sterol Esterase/genetics/*metabolism
EDAT- 1999/08/13 00:00
MHDA- 1999/08/13 00:01
CRDT- 1999/08/13 00:00
PHST- 1999/08/13 00:00 [pubmed]
PHST- 1999/08/13 00:01 [medline]
PHST- 1999/08/13 00:00 [entrez]
AID - S1097-2765(00)80192-6 [pii]
AID - 10.1016/s1097-2765(00)80192-6 [doi]
PST - ppublish
SO  - Mol Cell. 1999 Jul;4(1):109-15. doi: 10.1016/s1097-2765(00)80192-6.