PMID- 10434059
OWN - NLM
STAT- MEDLINE
DCOM- 19990927
LR  - 20191210
IS  - 0006-3002 (Print)
IS  - 0006-3002 (Linking)
VI  - 1428
IP  - 2-3
DP  - 1999 Aug 5
TI  - Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes 
      in the mouse.
PG  - 397-405
AB  - The plasma membrane calcium ATPases are critical components in the regulation of 
      cellular calcium homeostasis and signaling. In mammals, there are 4 Pmca genes,
      and information on the cellular and tissue distribution of their expression
      during development will provide insight into the regulation and possible function
      of each Pmca isoform. Using specific probes and in situ hybridization, we found
      that the four Pmca genes are expressed in spatially overlapping but distinct
      patterns in the mouse embryo. The dynamic temporal patterns of expression
      indicate that the individual isoforms are subject to both positive and negative
      regulation. The differential and restricted expression of Pmca genes supports the
      notion that they play unique functional roles in mammalian development.
FAU - Zacharias, D A
AU  - Zacharias DA
AD  - Department of Biochemistry and Molecular Biology, Samuel C. Johnson Medical
      Research Center, Mayo Clinic Scottsdale, 13400 E. Shea Boulevard, Scottsdale, AZ 
      85259, USA.
FAU - Kappen, C
AU  - Kappen C
LA  - eng
GR  - 5-T32GM08288-08/GM/NIGMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Biochim Biophys Acta
JT  - Biochimica et biophysica acta
JID - 0217513
RN  - 0 (Cation Transport Proteins)
RN  - 0 (Coloring Agents)
RN  - 0 (DNA, Complementary)
RN  - 0 (RNA, Messenger)
RN  - EC 3.6.3.8 (Plasma Membrane Calcium-Transporting ATPases)
RN  - EC 7.2.2.10 (Calcium-Transporting ATPases)
SB  - IM
MH  - Animals
MH  - Calcium-Transporting ATPases/*genetics
MH  - Cation Transport Proteins
MH  - Cells, Cultured
MH  - Coloring Agents
MH  - DNA Fragmentation
MH  - DNA, Complementary/metabolism
MH  - Embryo, Mammalian
MH  - Female
MH  - Gene Expression Regulation, Developmental
MH  - Gene Expression Regulation, Enzymologic
MH  - In Situ Hybridization
MH  - Liver/embryology
MH  - Male
MH  - Mice
MH  - Nervous System/embryology
MH  - Plasma Membrane Calcium-Transporting ATPases
MH  - RNA, Messenger/metabolism
MH  - Stem Cells/metabolism
MH  - Time Factors
MH  - Urinary Bladder/embryology
EDAT- 1999/08/06 00:00
MHDA- 1999/08/06 00:01
CRDT- 1999/08/06 00:00
PHST- 1999/08/06 00:00 [pubmed]
PHST- 1999/08/06 00:01 [medline]
PHST- 1999/08/06 00:00 [entrez]
AID - S0304-4165(99)00058-6 [pii]
AID - 10.1016/s0304-4165(99)00058-6 [doi]
PST - ppublish
SO  - Biochim Biophys Acta. 1999 Aug 5;1428(2-3):397-405. doi:
      10.1016/s0304-4165(99)00058-6.