PMID- 10433813
OWN - NLM
STAT- MEDLINE
DCOM- 19990924
LR  - 20061115
IS  - 1044-7431 (Print)
IS  - 1044-7431 (Linking)
VI  - 14
IP  - 1
DP  - 1999 Jul
TI  - Cloning and expression of mouse Cadherin-7, a type-II cadherin isolated from the 
      developing eye.
PG  - 1-16
AB  - We report the molecular cloning of Cadherin-7 from the embryonic mouse eye. The
      deduced amino acid sequence shows it to be a type-II cadherin similar to Xenopus 
      F-cadherin and chick Cadherin-7. The mouse Cadherin-7 gene maps to chromosome 1, 
      outside the conserved linkage group of cadherin genes on chromosome 8. Cadherin-7
      is expressed throughout the entire period of neural development and mRNA levels
      are developmentally regulated in both the embryonic and the postnatal central
      nervous system (CNS). In adult mice, Cadherin-7 expression is restricted to the
      CNS, with highest levels in the retina. In the developing eye, Cadherin-7 mRNA is
      found only in the neural retina. It is expressed by all retinal neuroblasts from 
      E11 onward, but becomes progressively restricted to neurons in the inner
      neuroblast and developing ganglion cell layers (GCL). In the adult retina it is
      confined to subpopulations of cells in the GCL and to amacrine cells in the inner
      part of the inner nuclear layer. This expression pattern suggests a role for
      Cadherin-7 in mouse retinal development, particularly in the formation and
      maintenance of the GCL.
CI  - Copyright 1999 Academic Press.
FAU - Faulkner-Jones, B E
AU  - Faulkner-Jones BE
AD  - Department of Anatomy and Cell Biology, The Howard Florey Institute, Parkville,
      Victoria, 3052, Australia.
FAU - Godinho, L N
AU  - Godinho LN
FAU - Reese, B E
AU  - Reese BE
FAU - Pasquini, G F
AU  - Pasquini GF
FAU - Ruefli, A
AU  - Ruefli A
FAU - Tan, S S
AU  - Tan SS
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Mol Cell Neurosci
JT  - Molecular and cellular neurosciences
JID - 9100095
RN  - 0 (CDH7 protein, human)
RN  - 0 (Cadherins)
RN  - 0 (RNA, Messenger)
RN  - 0 (Recombinant Proteins)
SB  - IM
MH  - Aging
MH  - Amino Acid Sequence
MH  - Animals
MH  - Brain/embryology/growth & development/*physiology
MH  - Cadherins/biosynthesis/chemistry/*genetics
MH  - *Chromosome Mapping
MH  - Cloning, Molecular
MH  - Embryonic and Fetal Development
MH  - Eye/*embryology/*growth & development
MH  - *Gene Expression Regulation, Developmental
MH  - Head
MH  - Mice
MH  - Molecular Sequence Data
MH  - RNA, Messenger/analysis
MH  - Recombinant Proteins/biosynthesis/chemistry
MH  - Retinal Ganglion Cells/cytology/physiology
MH  - Sequence Alignment
MH  - Sequence Homology, Amino Acid
MH  - Transcription, Genetic
EDAT- 1999/08/06 00:00
MHDA- 1999/08/06 00:01
CRDT- 1999/08/06 00:00
PHST- 1999/08/06 00:00 [pubmed]
PHST- 1999/08/06 00:01 [medline]
PHST- 1999/08/06 00:00 [entrez]
AID - 10.1006/mcne.1999.0764 [doi]
AID - S1044-7431(99)90764-9 [pii]
PST - ppublish
SO  - Mol Cell Neurosci. 1999 Jul;14(1):1-16. doi: 10.1006/mcne.1999.0764.