PMID- 10424889
OWN - NLM
STAT- MEDLINE
DCOM- 19990908
LR  - 20170214
IS  - 0022-1554 (Print)
IS  - 0022-1554 (Linking)
VI  - 47
IP  - 8
DP  - 1999 Aug
TI  - Ultrastructural distribution of 36-kD microfibril-associated glycoprotein
      (MAGP-36) in human and bovine tissues.
PG  - 1049-56
AB  - We observed the ultrastructural distribution of MAGP-36 by immunoelectron
      microscopy in human and bovine tissues. MAGP-36 was present in microfibrils
      associated with tropoelastin in skin, aorta, and spleen. It was not detected in
      microfibrils from the ocular zonule and kidney mesangium that were not associated
      with tropoelastin. In skin, MAGP-36 was present in both early immature elastic
      fibers and mature elastic fibers. In mature elastic fibers, MAGP-36 was localized
      around amorphous elastic cores at the elastin-microfibril interface and in
      electron-dense bundles. Localization of MAGP-36 in elastic fibers coincided with 
      the distribution of lysyl oxidase, an enzyme that plays a pivotal role in the
      deposition of tropoelastin. These findings suggest that MAGP-36 may be involved
      in elastogenesis.
FAU - Toyoshima, T
AU  - Toyoshima T
AD  - Department of Biology, Kagawa Medical University, Kagawa, Japan.
FAU - Yamashita, K
AU  - Yamashita K
FAU - Furuichi, H
AU  - Furuichi H
FAU - Shishibori, T
AU  - Shishibori T
FAU - Itano, T
AU  - Itano T
FAU - Kobayashi, R
AU  - Kobayashi R
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Histochem Cytochem
JT  - The journal of histochemistry and cytochemistry : official journal of the
      Histochemistry Society
JID - 9815334
RN  - 0 (Contractile Proteins)
RN  - 0 (Glycoproteins)
RN  - 0 (MAGP-36 protein, human)
RN  - 0 (Tropoelastin)
SB  - IM
MH  - Animals
MH  - Antibody Specificity
MH  - Aorta/*metabolism
MH  - Cattle
MH  - Cicatrix, Hypertrophic/metabolism
MH  - Contractile Proteins/immunology/*metabolism
MH  - Glycoproteins
MH  - Humans
MH  - Kidney/metabolism
MH  - Microscopy, Immunoelectron
MH  - Skin/*metabolism
MH  - Spleen/metabolism
MH  - Tropoelastin/metabolism
EDAT- 1999/07/29 00:00
MHDA- 1999/07/29 00:01
CRDT- 1999/07/29 00:00
PHST- 1999/07/29 00:00 [pubmed]
PHST- 1999/07/29 00:01 [medline]
PHST- 1999/07/29 00:00 [entrez]
AID - 10.1177/002215549904700809 [doi]
PST - ppublish
SO  - J Histochem Cytochem. 1999 Aug;47(8):1049-56. doi: 10.1177/002215549904700809.