PMID- 10390649
OWN - NLM
STAT- MEDLINE
DCOM- 19990817
LR  - 20190915
IS  - 0165-6147 (Print)
IS  - 0165-6147 (Linking)
VI  - 20
IP  - 7
DP  - 1999 Jul
TI  - Neurotensin and neurotensin receptors.
PG  - 302-9
AB  - Neurotensin is a brain and gastrointestinal peptide that fulfils many central and
      peripheral functions through its interaction with specific receptors. Three
      subtypes of neurotensin receptors have been cloned. Two of them belong to the
      family of G protein-coupled receptors, whereas the third one is an entirely new
      type of neuropeptide receptor and is identical to gp95/sortilin, a 100
      kDa-protein with a single transmembrane domain. In this review, the present
      knowledge regarding the molecular and pharmacological properties of the three
      cloned neurotensin receptors is summarized and the relationship between these
      receptors and the known pharmacological effects of neurotensin is discussed.
FAU - Vincent, J P
AU  - Vincent JP
AD  - Institut de Pharmacologie Moleculaire et Cellulaire, Unite Propre de Recherche
      411 du Centre National de la Recherche Scientifique, 660 route des Lucioles,
      Sophia-Antipolis, 06560 Valbonne, France.
FAU - Mazella, J
AU  - Mazella J
FAU - Kitabgi, P
AU  - Kitabgi P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Trends Pharmacol Sci
JT  - Trends in pharmacological sciences
JID - 7906158
RN  - 0 (RNA, Messenger)
RN  - 0 (Receptors, Neurotensin)
RN  - 39379-15-2 (Neurotensin)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Humans
MH  - Molecular Sequence Data
MH  - Neurotensin/genetics/*physiology
MH  - RNA, Messenger/metabolism
MH  - Receptors, Neurotensin/genetics/*physiology
RF  - 67
EDAT- 1999/07/03 00:00
MHDA- 1999/07/03 00:01
CRDT- 1999/07/03 00:00
PHST- 1999/07/03 00:00 [pubmed]
PHST- 1999/07/03 00:01 [medline]
PHST- 1999/07/03 00:00 [entrez]
AID - S0165-6147(99)01357-7 [pii]
AID - 10.1016/s0165-6147(99)01357-7 [doi]
PST - ppublish
SO  - Trends Pharmacol Sci. 1999 Jul;20(7):302-9. doi: 10.1016/s0165-6147(99)01357-7.